{"meta":{"query_hash":"1a1b89dade39","filters":{"topic":"CRISPR and Genetic Engineering"},"cohort_total":2698,"direct_labels_cover":7,"predictions_cover":2698,"exported":2698,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/1a1b89dade39","api":"https://metacan.xera.ac/api/v1/cohort?topic=CRISPR+and+Genetic+Engineering"},"results":[{"id":"W1034687404","doi":"10.1007/978-1-4939-2389-2_6","title":"Somatic Cell Nuclear Transfer and the Creation of Transgenic Large Animal Models","year":2015,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Somatic cell nuclear transfer; Somatic cell; Transgene; Cell biology; Biology; Genetics; Gene; Embryo","score_opus":0.011395236009139225,"score_gpt":0.2445291181008398,"score_spread":0.23313388209170058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1034687404","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.035558574,0.009545605,0.06334137,0.00011396001,0.00007771797,0.00071731914,0.00012204395,0.000025209694,0.8904982],"genre_scores_gemma":[0.94670546,0.0011268512,0.00019469278,0.0000306666,0.0000637001,0.000003544127,0.000051890907,0.000044346973,0.051778864],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994103,0.000009352128,0.00019149436,0.00017834251,0.00010524157,0.00010527733],"domain_scores_gemma":[0.99966973,0.000006681607,0.000023033184,0.00020991133,0.00004704523,0.000043583943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013205958,0.00016332496,0.00020262845,0.000023137653,0.0000230232,0.000008097013,0.00009397323,0.00021576387,0.00010843155],"category_scores_gemma":[0.000002163821,0.000117850504,0.00011530494,0.0000065147415,0.00006807158,0.0000015187966,0.000024336381,0.000077761826,0.0000037831192],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014898946,0.00012886016,0.000006720961,0.0012205227,0.00076350523,0.0000033158872,0.0027749215,0.0033235308,0.6096463,0.37424365,0.0033286246,0.003070115],"study_design_scores_gemma":[0.02386918,0.002692734,0.00006565903,0.00036780772,0.002264915,0.00007779336,0.0007600699,0.05417744,0.30609325,0.037806064,0.56886804,0.0029570635],"about_ca_topic_score_codex":0.0000046159075,"about_ca_topic_score_gemma":0.000013028616,"teacher_disagreement_score":0.9111469,"about_ca_system_score_codex":0.0000034371421,"about_ca_system_score_gemma":0.000023290248,"threshold_uncertainty_score":0.48058042},"labels":[],"label_agreement":null},{"id":"W103580390","doi":"10.1007/3-540-36028-x_11","title":"Gene Therapy: Role in Myocardial Protection","year":2006,"lang":"en","type":"review","venue":"Handbook of experimental pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Heart failure; Genetic enhancement; Disease; Coronary artery disease; Cardiology; Intensive care medicine; Restenosis; Gene delivery; Internal medicine; Bioinformatics; Gene; Biology; Stent","score_opus":0.02283316218999685,"score_gpt":0.3727639665745377,"score_spread":0.34993080438454083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W103580390","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012876929,0.9967102,0.00020531895,0.0000013404228,0.00047893173,0.0009039311,0.00002065374,0.000010001691,0.0003819677],"genre_scores_gemma":[0.0029250784,0.9954908,0.00015513499,0.000028730548,0.0006003225,0.00049114204,0.0001666,0.000052773186,0.000089414505],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987545,0.00010960076,0.000405186,0.00037241305,0.00008298681,0.00027531147],"domain_scores_gemma":[0.99963254,0.000006862058,0.00013318373,0.0001669297,0.000016750895,0.000043757493],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010005709,0.00030014486,0.0006624224,0.0001252864,0.000025872961,0.000005516922,0.00016924994,0.0003271333,0.000054900764],"category_scores_gemma":[0.000002258456,0.00029102745,0.0002912444,0.00008140496,0.0000645243,0.0000019928036,0.00010885086,0.00015489724,0.0000074141944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054266027,0.00015489016,0.0000012453819,0.00025822988,0.00012040368,0.000004842881,0.000021384212,0.000041555024,0.820977,7.605465e-7,0.0007905091,0.17757495],"study_design_scores_gemma":[0.0005130518,0.00019423527,7.3960894e-7,0.00015608908,0.00003317465,0.000017686756,0.0000053356143,0.0000047352114,0.5220388,0.0000010650647,0.47688088,0.00015420809],"about_ca_topic_score_codex":0.00003825724,"about_ca_topic_score_gemma":0.000002563073,"teacher_disagreement_score":0.47609037,"about_ca_system_score_codex":0.000044946075,"about_ca_system_score_gemma":0.0000893112,"threshold_uncertainty_score":0.99995416},"labels":[],"label_agreement":null},{"id":"W1040091980","doi":"","title":"The Protein Inhibitor of Activated Stat 3 (PIAS3) Interacts With the Forkhead Transcription Factor FOXC2 in HTM Cells","year":2008,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"stat; Transcription factor; Chemistry; Cancer research; Cell biology; STAT3; Biology; Signal transduction; Gene; Biochemistry","score_opus":0.022590422851670115,"score_gpt":0.3166459534626406,"score_spread":0.29405553061097045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1040091980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99887675,0.00011117132,0.00007134738,0.00029976474,0.000097373086,0.00042441263,0.000007040099,0.0000056741223,0.00010644077],"genre_scores_gemma":[0.9994317,0.0000105454865,0.00027473844,0.000039187646,0.000036101323,0.00005257267,0.0000037460056,0.000011469319,0.00013988586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878347,0.00010648741,0.00020588696,0.00033791756,0.00022302376,0.00034321175],"domain_scores_gemma":[0.9994129,0.000050612525,0.00010277528,0.00021672186,0.00012897665,0.00008803684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002922639,0.00015949688,0.00013564601,0.000056070687,0.0002436682,0.00001695262,0.00036254272,0.00007763719,0.000005398143],"category_scores_gemma":[0.00013229056,0.00009224766,0.000036090125,0.00042960254,0.0025902959,0.000018621156,0.00007724161,0.00018190002,0.00000183986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085140295,0.000039171788,0.0013413717,0.0000067304977,0.000009845692,0.000010838533,0.0009475413,0.00020611375,0.99716663,0.000007608888,0.000021901711,0.00015707736],"study_design_scores_gemma":[0.00027267323,0.0008118585,0.023966193,0.000030753006,0.0000028003642,0.00006014146,0.0003480038,0.000091641145,0.97408664,0.00004638447,0.00016573477,0.000117195465],"about_ca_topic_score_codex":0.00006815394,"about_ca_topic_score_gemma":0.00003850573,"teacher_disagreement_score":0.023080038,"about_ca_system_score_codex":0.000029240346,"about_ca_system_score_gemma":0.00022591486,"threshold_uncertainty_score":0.95440525},"labels":[],"label_agreement":null},{"id":"W1075307096","doi":"10.1128/microbiolspec.plas-0034-2014","title":"The CRISPR-Cas Immune System and Genetic Transfers: Reaching an Equilibrium","year":2015,"lang":"en","type":"review","venue":"Microbiology Spectrum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Mobile genetic elements; Horizontal gene transfer; Plasmid; Biology; Bacterial conjugation; Genome editing; Transduction (biophysics); Genetics; Gene; DNA; Transformation (genetics); Computational biology; Bacteria; Palindrome; Genome","score_opus":0.01602699189465583,"score_gpt":0.3098588341976816,"score_spread":0.2938318423030258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1075307096","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014140685,0.9954792,0.0014775168,0.000041203642,0.00065781694,0.000602983,0.0001093316,0.000050199185,0.00016765567],"genre_scores_gemma":[0.0044486295,0.9937288,0.00022247154,0.000016042753,0.000621206,0.00006125619,0.0005225972,0.00011188893,0.00026707698],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976594,0.00031788685,0.00060360134,0.00075099774,0.000051333995,0.0006167924],"domain_scores_gemma":[0.99875504,0.000033188844,0.00013693566,0.0008925514,0.000032444685,0.00014981568],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043649087,0.0005592525,0.0009611982,0.00007674764,0.00017134285,0.00007749757,0.0005696058,0.00065527135,0.0000028840495],"category_scores_gemma":[0.000020153744,0.00040014368,0.00028500918,0.000092705974,0.00019812056,0.0000031486052,0.00021336667,0.00039462044,0.000018634873],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011047187,0.000086966254,0.00001819677,0.008817106,0.0014116452,0.00011358132,0.0002787763,0.000058148016,0.20407154,0.00025890765,0.0018969311,0.78287774],"study_design_scores_gemma":[0.00026318143,0.00044376557,0.000006151468,0.0005301113,0.00037465547,0.0024131618,0.000089199944,0.000013256201,0.0040829345,0.000008734995,0.9912428,0.0005320444],"about_ca_topic_score_codex":0.000029556677,"about_ca_topic_score_gemma":0.00008382835,"teacher_disagreement_score":0.98934585,"about_ca_system_score_codex":0.00007342532,"about_ca_system_score_gemma":0.00016028018,"threshold_uncertainty_score":0.999845},"labels":[],"label_agreement":null},{"id":"W1120205611","doi":"10.7202/1044645ar","title":"L’éthique et l’acceptation sociale des innovations technologiques","year":2018,"lang":"fr","type":"article","venue":"Les ateliers de l éthique","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Humanities; Political science; Philosophy","score_opus":0.015173383124758348,"score_gpt":0.3211440815672887,"score_spread":0.30597069844253033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1120205611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.52881765,0.008971693,0.43536708,0.0053402944,0.0006294035,0.00044553925,0.000057632635,0.00016023905,0.020210475],"genre_scores_gemma":[0.95248526,0.0056232736,0.03641028,0.0020400728,0.0007379658,0.0000893932,0.00011346616,0.00005670173,0.0024435807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855494,0.00017126072,0.00031389957,0.00037471563,0.000094914096,0.00049024075],"domain_scores_gemma":[0.9990092,0.000041842093,0.00010151282,0.0003193919,0.00044086718,0.00008718223],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00058886764,0.00025716188,0.00017906724,0.000107530075,0.00025202666,0.000078009674,0.0002416076,0.0013024465,0.00009456859],"category_scores_gemma":[0.0006781858,0.00030383482,0.00010135785,0.00032772886,0.0007270419,0.000015959695,0.00012822385,0.0005280963,0.000035516503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053985765,0.00015945303,0.0052024117,0.00029282056,0.00022002736,0.00001433964,0.0018611215,0.00065359403,0.6505059,0.15637788,0.005990503,0.17866799],"study_design_scores_gemma":[0.00040481845,0.0006597558,0.004333951,0.0001596287,0.000049943075,0.00007258018,0.001263036,0.0005934292,0.8092038,0.025287429,0.15742224,0.0005493631],"about_ca_topic_score_codex":0.00024924567,"about_ca_topic_score_gemma":0.0018346276,"teacher_disagreement_score":0.42366764,"about_ca_system_score_codex":0.00013805623,"about_ca_system_score_gemma":0.00030190838,"threshold_uncertainty_score":0.9999941},"labels":[],"label_agreement":null},{"id":"W1127418603","doi":"10.1017/cbo9780511642364.001","title":"Introduction: gene transfer lost in translation","year":2009,"lang":"en","type":"book-chapter","venue":"Cambridge University Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Translation (biology); Gene transfer; Gene; Computer science; Genetics; Biology","score_opus":0.010673793112769642,"score_gpt":0.21083950828533218,"score_spread":0.20016571517256254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1127418603","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017704077,0.0010094722,0.0091172075,0.00006362646,0.00019697248,0.00030354818,0.00009007356,0.000023052295,0.9874256],"genre_scores_gemma":[0.009718149,0.0005311249,0.0002087854,0.00003282014,0.0007243362,3.7387116e-7,0.00027200617,0.00003287369,0.98847955],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991774,0.000012985953,0.00013668065,0.0004087636,0.00009736841,0.00016682212],"domain_scores_gemma":[0.9995553,0.000003427432,0.00002339231,0.00030915882,0.000043313605,0.00006542334],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000048721988,0.00022833407,0.00018681496,0.00009869085,0.00003363605,0.000010567877,0.00015479018,0.00034853956,0.0000062213285],"category_scores_gemma":[0.0000017135507,0.00029968537,0.00012564458,0.000006615822,0.000050426188,0.0000026703644,0.000027140373,0.00019793282,0.000004674847],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015933557,0.00011812544,0.000013298242,0.00042112317,0.0006596442,0.00053857086,0.00025892566,0.0037355835,0.57323384,0.23545524,0.07319194,0.11078036],"study_design_scores_gemma":[0.0005363055,0.000084507265,0.000033328,0.000022715347,0.00005845669,0.00001812815,0.0000052462383,0.0000324256,0.057857342,0.0000015732855,0.9410447,0.00030528937],"about_ca_topic_score_codex":0.000011235738,"about_ca_topic_score_gemma":0.00000818714,"teacher_disagreement_score":0.86785275,"about_ca_system_score_codex":0.000036424262,"about_ca_system_score_gemma":0.00003769361,"threshold_uncertainty_score":0.9999455},"labels":[],"label_agreement":null},{"id":"W141059169","doi":"10.1016/s0076-6879(10)77014-2","title":"A Wider Context for Gene Trap Mutagenesis","year":2010,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Biology; Gene; Gene targeting; Homologous recombination; Mutagenesis; Embryonic stem cell; Computational biology; Genetics; Context (archaeology); Mutant","score_opus":0.03227608534425306,"score_gpt":0.43908478544334284,"score_spread":0.40680870009908976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W141059169","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.50723594,0.0015069777,0.48620394,0.00034475647,0.0031018734,0.0008245879,0.000035504294,0.000053689633,0.00069272466],"genre_scores_gemma":[0.26295993,0.00014066226,0.73374903,0.0013355425,0.00046092013,0.0006191767,0.000059595568,0.00012479763,0.00055032456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929668,0.0027238356,0.0011889562,0.001622051,0.00014947764,0.0013489133],"domain_scores_gemma":[0.9958212,0.0022181778,0.00025057612,0.0013378755,0.00014190613,0.00023028642],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0063869776,0.00072429347,0.0012095727,0.0006861265,0.00012569164,0.000024552019,0.00087240024,0.0017641126,0.00018833965],"category_scores_gemma":[0.0041234596,0.0007622311,0.00037730107,0.00048718925,0.0005666831,0.000010126919,0.0002833692,0.0011267784,0.000012357952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004166441,0.00028454963,0.0021046982,0.00004531192,0.000096862335,0.000052591637,0.00025406195,0.0007229638,0.87361413,0.0016159919,0.00044851692,0.12034369],"study_design_scores_gemma":[0.0037618533,0.0014462487,0.042745166,0.000023216624,0.00007119794,0.00054488686,0.00022812969,0.00039913543,0.87328637,0.007051262,0.069388285,0.0010542638],"about_ca_topic_score_codex":0.00014358542,"about_ca_topic_score_gemma":0.002017981,"teacher_disagreement_score":0.24754512,"about_ca_system_score_codex":0.00006414543,"about_ca_system_score_gemma":0.00015764483,"threshold_uncertainty_score":0.9995318},"labels":[],"label_agreement":null},{"id":"W1439532443","doi":"10.1089/hgtb.2013.128","title":"Improved Detection of Transgene and Nonviral Vectors in Blood","year":2013,"lang":"en","type":"article","venue":"Human Gene Therapy Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"World Anti-Doping Agency; Australian Government","keywords":"Transgene; Biology; genomic DNA; Gene; Genetic enhancement; Plasmid; Gene delivery; Computational biology; Vector (molecular biology); Molecular biology; Transgenesis; Genetics; Recombinant DNA; Reproductive technology","score_opus":0.015387334261261721,"score_gpt":0.3493493773120764,"score_spread":0.33396204305081467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1439532443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93755347,0.0030043179,0.059156753,0.000005680703,0.000051064537,0.00017874048,0.0000010949163,0.0000064134015,0.000042490752],"genre_scores_gemma":[0.9735699,0.0005900135,0.025639355,0.000019725832,0.00006948658,0.00003277321,0.0000052396335,0.000018724126,0.00005474627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993749,0.000094616466,0.0001711451,0.00018809247,0.00003545063,0.00013579754],"domain_scores_gemma":[0.99972403,0.0000088731895,0.000032396223,0.0001761647,0.000022515236,0.00003601543],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024901787,0.00010736597,0.00013147526,0.000054743432,0.00002418221,0.0000074588374,0.00006780933,0.00008992722,0.00002218551],"category_scores_gemma":[0.000007965423,0.00010276277,0.00004656191,0.00005853695,0.000035352456,0.0000023721154,0.000016446224,0.000053963322,2.2678981e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017325605,0.000028551693,0.00045235144,0.0000088469615,0.000029228004,1.6469764e-7,0.00011874549,0.000035550824,0.950802,0.0000020127302,8.3845583e-7,0.04850438],"study_design_scores_gemma":[0.00075257214,0.00042236308,0.025510756,0.000002538989,0.0000073899237,0.000005408632,0.000023022865,0.00016327284,0.9727755,0.00007727904,0.00014928792,0.000110609886],"about_ca_topic_score_codex":0.00010590809,"about_ca_topic_score_gemma":0.000035009056,"teacher_disagreement_score":0.04839377,"about_ca_system_score_codex":0.0000028278475,"about_ca_system_score_gemma":0.0000067545134,"threshold_uncertainty_score":0.41905442},"labels":[],"label_agreement":null},{"id":"W1454215067","doi":"10.1007/978-1-4939-1053-3_1","title":"Error-Prone PCR and Effective Generation of Gene Variant Libraries for Directed Evolution","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Directed evolution; Gene; Cloning (programming); Computational biology; Genetics; Mutagenesis; Biology; clone (Java method); Sequence (biology); Plasmid; Restriction enzyme; Sequence space; DNA sequencing; Mutation; Computer science","score_opus":0.014271299157466617,"score_gpt":0.3684219783189495,"score_spread":0.3541506791614829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1454215067","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13904487,0.001611014,0.85876197,0.000028557914,0.00014295359,0.00031964044,0.00001045124,0.000010394425,0.00007018129],"genre_scores_gemma":[0.36617455,0.00002339716,0.6334673,0.000036589983,0.00008132607,0.00008897794,0.00010020822,0.000014360058,0.000013314148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988076,0.00046993623,0.00020349726,0.0003177953,0.000028262897,0.00017290664],"domain_scores_gemma":[0.9995758,0.000079607074,0.00006019051,0.00020282633,0.000048916045,0.00003264351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006841184,0.00012676009,0.0002099179,0.0000770943,0.000027613778,0.0000058611204,0.00007723904,0.000224519,0.0000016120381],"category_scores_gemma":[0.0005930855,0.00012395506,0.000046207104,0.000081670936,0.00008538789,0.0000021315343,0.000055355977,0.000058567635,1.2215902e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045556048,0.000017141805,0.0004621662,0.000027306256,0.00003403097,3.457858e-7,0.00003179819,0.0006428965,0.9815953,0.0031524487,0.000012686489,0.013978362],"study_design_scores_gemma":[0.00057976675,0.00044505092,0.0021008502,0.0000057098655,0.000021598407,0.000008479317,0.000009416235,0.013704776,0.9793469,0.002388115,0.0012496498,0.00013970297],"about_ca_topic_score_codex":0.000016472144,"about_ca_topic_score_gemma":0.0000093038525,"teacher_disagreement_score":0.22712967,"about_ca_system_score_codex":0.000009324463,"about_ca_system_score_gemma":0.000020240475,"threshold_uncertainty_score":0.5054741},"labels":[],"label_agreement":null},{"id":"W14581506","doi":"10.1007/978-3-642-34657-6_7","title":"Type II: Streptococcus thermophilus","year":2012,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Trans-activating crRNA; Plasmid; Streptococcus thermophilus; Biology; Gene; Genetics; Cas9; DNA; Bacteria","score_opus":0.011707332716895282,"score_gpt":0.2725092679787005,"score_spread":0.26080193526180523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W14581506","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011155459,0.010020933,0.0005833072,0.000034307814,0.00047011758,0.00021126246,0.000018672023,0.000033570395,0.9875123],"genre_scores_gemma":[0.11705572,0.0010455406,0.0002619256,0.0001261205,0.001207781,0.0000061104515,0.00022991671,0.000088141285,0.8799787],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99928766,0.0000027497824,0.00014667066,0.0002636185,0.00009345237,0.0002058237],"domain_scores_gemma":[0.9993682,0.0000028322863,0.000042632488,0.00044116197,0.000051994593,0.0000932116],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004530622,0.00025023028,0.00015733323,0.000031628068,0.00004337517,0.000010224567,0.00014688715,0.0003815439,0.0019872116],"category_scores_gemma":[0.000006708044,0.00022812879,0.00011330949,0.000008411569,0.000030879244,6.610659e-7,0.00017675787,0.00012336002,0.00016445518],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012576515,0.00009972976,0.00016320408,0.0001707839,0.0010744727,0.000019995985,0.00012385339,0.00023428338,0.64630944,0.055456147,0.121942766,0.17427959],"study_design_scores_gemma":[0.0001143718,0.00016336999,0.000049625083,0.0000144935,0.00003964331,0.000008392201,0.0000024529502,0.000003648966,0.023501953,0.00023822913,0.9755266,0.0003372778],"about_ca_topic_score_codex":0.0000019903316,"about_ca_topic_score_gemma":0.0000051188385,"teacher_disagreement_score":0.85358375,"about_ca_system_score_codex":0.000008397424,"about_ca_system_score_gemma":0.00003451346,"threshold_uncertainty_score":0.9989251},"labels":[],"label_agreement":null},{"id":"W1483456869","doi":"10.1016/s0076-6879(02)50957-5","title":"Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method","year":2002,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2986,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transformation (genetics); Yeast; Transformation efficiency; Oligonucleotide; DNA; Polyethylene glycol; Microtiter plate; Plasmid; Chemistry; Protocol (science); Computational biology; Combinatorial chemistry; Molecular biology; Computer science; Biology; Biochemistry; Chromatography; Gene; Medicine","score_opus":0.028593956938038644,"score_gpt":0.38831660044461636,"score_spread":0.35972264350657773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1483456869","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26097685,0.0032386743,0.72881675,0.00040697205,0.0013568496,0.0008118386,0.00010865657,0.00005907866,0.004224359],"genre_scores_gemma":[0.25584987,0.0004164743,0.74197537,0.00046289852,0.0001515417,0.0001984775,0.000081998514,0.00010514525,0.0007582194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9897115,0.006053773,0.0016184062,0.0012226142,0.00025137007,0.0011422868],"domain_scores_gemma":[0.9972504,0.0010164873,0.00036533014,0.0010294146,0.00012677506,0.00021163099],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.005452508,0.0007114977,0.0013669146,0.00070366805,0.00008322138,0.00001801319,0.00072077976,0.0015139262,0.0003077598],"category_scores_gemma":[0.0013924313,0.0007530555,0.00032568525,0.0007593086,0.00048794918,0.000021520316,0.00016465833,0.000958569,0.000008010611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003501556,0.00044821648,0.00036922825,0.000098614546,0.00011137858,0.000026336022,0.0013848646,0.0018464304,0.91977775,0.00027762,0.0005648554,0.07474454],"study_design_scores_gemma":[0.0032555906,0.0015428305,0.0046073776,0.000054182023,0.00007331061,0.00028372023,0.00034360914,0.0009126748,0.9659796,0.0013890737,0.020813392,0.0007446361],"about_ca_topic_score_codex":0.00013806246,"about_ca_topic_score_gemma":0.00033549164,"teacher_disagreement_score":0.073999904,"about_ca_system_score_codex":0.00011687157,"about_ca_system_score_gemma":0.000059206166,"threshold_uncertainty_score":0.9997823},"labels":[],"label_agreement":null},{"id":"W1500856445","doi":"10.1093/nar/gkv546","title":"The Cas6e ribonuclease is not required for interference and adaptation by the<i>E. coli</i>type I-E CRISPR-Cas system","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Agence Nationale de la Recherche","keywords":"Trans-activating crRNA; CRISPR; Biology; CRISPR interference; RNA; Genetics; DNA; Cas9; Transcription (linguistics); Nuclease; Endoribonuclease; Computational biology; Gene; RNase P","score_opus":0.07560576551895158,"score_gpt":0.38101020896636273,"score_spread":0.30540444344741113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1500856445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96591735,0.0047326805,0.023432327,0.0030662655,0.0003952269,0.0010338069,0.00010189611,0.000033801425,0.0012866436],"genre_scores_gemma":[0.9977566,0.00022783388,0.00031527661,0.00011310431,0.00015970039,0.000068132445,0.000024262774,0.000026208234,0.0013088759],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988068,0.000110391244,0.00017932117,0.00028210887,0.0002754628,0.000345915],"domain_scores_gemma":[0.9988884,0.00009550693,0.00003136361,0.00040155958,0.00043809594,0.00014507328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011371055,0.00010946617,0.000092134374,0.000027771097,0.00033095322,0.00012147941,0.00030685414,0.00010607194,0.0000028428103],"category_scores_gemma":[0.0004315868,0.000073722935,0.00003569235,0.00012660195,0.00018820883,0.000005416121,0.00017772037,0.0001475925,0.000015213046],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014508364,0.00004589615,0.000297457,0.00015216526,0.00010741975,0.000004462607,0.0024649461,0.00009125959,0.6737342,0.0011389186,0.28774795,0.03276447],"study_design_scores_gemma":[0.0015851563,0.0016387488,0.0004618932,0.00006375541,0.000032097567,0.00005207309,0.010748516,0.040319536,0.41404676,0.00018765929,0.5305176,0.0003462222],"about_ca_topic_score_codex":0.00009232795,"about_ca_topic_score_gemma":0.000041362884,"teacher_disagreement_score":0.25968745,"about_ca_system_score_codex":0.00004102706,"about_ca_system_score_gemma":0.000097414326,"threshold_uncertainty_score":0.3006334},"labels":[],"label_agreement":null},{"id":"W1504505784","doi":"10.1002/fes3.60","title":"Challenging regulations: Managing risks in crop biotechnology","year":2015,"lang":"en","type":"editorial","venue":"Food and Energy Security","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Animal and Plant Health Inspection Service; European Food Safety Authority","keywords":"Biotechnology; Crop; Agriculture; Biology; Genomics; Abiotic stress; Business; Agronomy; Genome; Genetics; Ecology","score_opus":0.010225801026610453,"score_gpt":0.28308866301914276,"score_spread":0.2728628619925323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1504505784","genre_codex":"editorial","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.061041333,0.15278018,0.0056396048,0.00070387585,0.77318895,0.0002551941,0.0002750505,0.0002218752,0.005893944],"genre_scores_gemma":[0.7593666,0.010010445,0.00015695777,0.000019306684,0.22934532,0.000036267964,0.00077415485,0.00006414763,0.00022684867],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987697,0.000033838165,0.00022600737,0.00050241797,0.00016287775,0.00030515686],"domain_scores_gemma":[0.9994176,0.000018815797,0.00006463667,0.0003571124,0.0000623333,0.00007950249],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019330338,0.00025851448,0.0002651189,0.00016753782,0.000053484706,0.000026037636,0.00017802085,0.0011200822,0.0000021742676],"category_scores_gemma":[0.000129115,0.00028610913,0.000055113178,0.000104401006,0.000059941885,0.0000030457913,0.00023480768,0.00033134894,7.428048e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015097382,0.00015793243,0.00008083038,0.00045942544,0.000363551,0.000038987117,0.0005138054,0.0051261964,0.006653758,0.0032766243,0.9607201,0.022457805],"study_design_scores_gemma":[0.00045518688,0.00023247064,0.00002263729,0.00006606634,0.00001883949,0.0000047747503,0.000068247355,0.0005251383,0.003795486,0.001596458,0.9928605,0.00035422057],"about_ca_topic_score_codex":0.00030498413,"about_ca_topic_score_gemma":0.0009459144,"teacher_disagreement_score":0.6983252,"about_ca_system_score_codex":0.00002623316,"about_ca_system_score_gemma":0.00006580395,"threshold_uncertainty_score":0.9999591},"labels":[],"label_agreement":null},{"id":"W1506632233","doi":"10.1002/yea.3010","title":"Genome-wide mapping of cellular traits using yeast","year":2014,"lang":"en","type":"article","venue":"Yeast","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Budding yeast; Yeast; Genome; Model organism; Computational biology; Genetics; Saccharomyces cerevisiae; Genetic variation; Allele; Synthetic biology; Evolutionary biology; Gene","score_opus":0.010128485481615254,"score_gpt":0.24259676188489304,"score_spread":0.23246827640327777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1506632233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7929258,0.0003174789,0.20547235,0.000010268606,0.00006943983,0.000048597798,0.0000071929735,0.0000065072745,0.0011423859],"genre_scores_gemma":[0.99693644,0.000008829637,0.002548047,0.000027864764,0.00027567908,0.000001670263,0.000019906622,0.000018074938,0.00016350824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994759,0.000014574925,0.00013163513,0.00015704463,0.00006901615,0.00015180378],"domain_scores_gemma":[0.9997173,0.0000026225262,0.000036238125,0.00016368959,0.000029537463,0.000050646195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008916262,0.000087777036,0.00010217929,0.000033378346,0.000023634986,0.0000064199007,0.000100332625,0.00006183309,0.000017689103],"category_scores_gemma":[0.000029113893,0.00009352632,0.00005957245,0.00005528946,0.000025594203,0.0000011547646,0.000047581285,0.000037293736,0.000006371045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038008545,0.000008264769,0.00086592406,0.00002730109,0.000015270693,4.778786e-7,0.00004602376,0.0016696476,0.99591523,0.000016647211,0.000019268402,0.0014121679],"study_design_scores_gemma":[0.0003339636,0.000062829335,0.034495138,0.000025167155,0.000016361812,0.000008720716,0.000085646876,0.0018040604,0.9229296,0.000019167463,0.040012185,0.00020715264],"about_ca_topic_score_codex":0.0000053926183,"about_ca_topic_score_gemma":0.0000027979033,"teacher_disagreement_score":0.20401064,"about_ca_system_score_codex":0.0000045533275,"about_ca_system_score_gemma":0.000015034956,"threshold_uncertainty_score":0.38138926},"labels":[],"label_agreement":null},{"id":"W1514698762","doi":"10.1074/jbc.m114.624999","title":"Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in β-Thalassemia Induced Pluripotent Stem Cells (iPSCs)","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences","keywords":"Induced pluripotent stem cell; Reprogramming; Biology; Genetics; Copy-number variation; Gene; Point mutation; Mutation; Genome; Embryonic stem cell","score_opus":0.04237944331273126,"score_gpt":0.2849714275140162,"score_spread":0.24259198420128497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1514698762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99805915,0.0013751829,0.00022901763,0.000044399483,0.00012426221,0.0001215406,0.000007781762,0.000011371647,0.000027297308],"genre_scores_gemma":[0.99878466,0.00016962491,0.0006649621,0.00003020974,0.00029914215,0.000005044418,0.000013085931,0.000019325962,0.000013973052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828804,0.00007428546,0.00066859985,0.000408401,0.00019755698,0.0003631254],"domain_scores_gemma":[0.99893594,0.000034863384,0.00027733555,0.00025912555,0.00014415104,0.00034859293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042564567,0.00027528265,0.00040698482,0.0000338673,0.000039144954,0.000040426614,0.00022778951,0.00038602873,0.000012487097],"category_scores_gemma":[0.00023000439,0.00020977692,0.00014091608,0.00008392822,0.000051140698,0.000007856528,0.00021876204,0.0004166754,7.7524396e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119431155,0.00012082909,0.015920509,0.000040263814,0.00004776503,0.00005258392,0.00009133027,0.00009325481,0.98205656,2.613681e-7,0.000010988249,0.0014462194],"study_design_scores_gemma":[0.0008879321,0.00034073455,0.015206317,0.000027328619,0.000016515565,0.000093679024,0.00043325228,0.000051477848,0.98223007,0.000013697201,0.00043765164,0.0002613474],"about_ca_topic_score_codex":0.000007110965,"about_ca_topic_score_gemma":0.0000024919846,"teacher_disagreement_score":0.001205558,"about_ca_system_score_codex":0.0001023841,"about_ca_system_score_gemma":0.000066886896,"threshold_uncertainty_score":0.85544544},"labels":[],"label_agreement":null},{"id":"W1516387975","doi":"10.1038/85808","title":"Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity","year":2001,"lang":"en","type":"article","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Biology; Loss of heterozygosity; Embryonic stem cell; Mutagenesis; Genetics; Transgene; Stem cell; Genome; Gene; Mutation; Cell biology; Allele","score_opus":0.007139536462912204,"score_gpt":0.2791786279113108,"score_spread":0.2720390914483986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1516387975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904796,0.002926298,0.0057819462,0.00006632048,0.00024105715,0.00038650393,0.00005956753,0.0000071479435,0.000051555748],"genre_scores_gemma":[0.99652106,0.0012520949,0.0018107607,0.00006327279,0.00012656937,0.000016061527,0.000043143853,0.000022557544,0.00014450654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998874,0.00003445806,0.00030513701,0.00038204988,0.00011368466,0.00029066985],"domain_scores_gemma":[0.99948287,0.0000192061,0.000067477005,0.0002505695,0.00012919404,0.00005070707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020236969,0.00016796277,0.000210664,0.00010259409,0.00002373831,0.0000069454104,0.00015629851,0.00047462076,0.0000011405679],"category_scores_gemma":[0.000019923553,0.00018460948,0.0000922895,0.00024070662,0.000030305957,0.0000022581144,0.00003433047,0.00024115028,5.150364e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068703544,0.00012863839,0.017719397,0.00008074919,0.000025732821,0.0000068072045,0.00013575128,0.021192156,0.9558182,0.0000041546564,0.0002595873,0.003941817],"study_design_scores_gemma":[0.0017708101,0.0004016105,0.034184895,0.000028121027,0.000015567359,0.000020805383,0.00003839138,0.0015151083,0.9572128,0.00002663082,0.0045725224,0.00021274785],"about_ca_topic_score_codex":0.000013136489,"about_ca_topic_score_gemma":0.00089377665,"teacher_disagreement_score":0.019677049,"about_ca_system_score_codex":0.000030042293,"about_ca_system_score_gemma":0.000045874433,"threshold_uncertainty_score":0.7528156},"labels":[],"label_agreement":null},{"id":"W1523483559","doi":"10.1007/978-1-60327-483-8_8","title":"Cre Recombinase Mediated Alterations of the Mouse Genome Using Embryonic Stem Cells","year":2008,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute","keywords":"Cre recombinase; Recombinase; Cre-Lox recombination; Biology; Homologous recombination; Site-specific recombination; Genetics; Genome; FLP-FRT recombination; DNA; Gene; Embryonic stem cell; Gene targeting; Transgene; Recombination; Genetic recombination; Genetically modified mouse","score_opus":0.042777558780593326,"score_gpt":0.43435618947046845,"score_spread":0.39157863068987514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1523483559","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00047246768,0.7222738,0.27638605,0.00000487884,0.00025317277,0.0004890675,0.000075386044,0.0000070479564,0.00003808813],"genre_scores_gemma":[0.000015231419,0.8808563,0.11849046,0.000038532544,0.000058715323,0.000057219808,0.00021065476,0.00007311054,0.00019981674],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99656934,0.0016720177,0.00072094495,0.00058389077,0.000077918616,0.00037586846],"domain_scores_gemma":[0.99850065,0.00008905248,0.00032641838,0.0009537261,0.00006323248,0.00006691716],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004876616,0.00042585458,0.001044206,0.00018263899,0.000060071467,0.000007847838,0.0006076846,0.0007304733,0.000011998863],"category_scores_gemma":[0.00013197472,0.00033284596,0.0005690072,0.00038740024,0.00016617004,0.0000012673621,0.0003636479,0.0003796468,0.0000022647503],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003510203,0.000049742885,0.0000048394586,0.0008272715,0.00017504078,0.000008647178,0.000021648175,0.0007975749,0.94623023,0.000036845035,0.000028959574,0.05181567],"study_design_scores_gemma":[0.00030202317,0.00012639623,0.0000013759907,0.0003139986,0.00018558296,0.000118962445,0.000011131287,0.00015026059,0.28048867,0.000022220043,0.71776056,0.00051879976],"about_ca_topic_score_codex":0.000015123162,"about_ca_topic_score_gemma":0.000007648749,"teacher_disagreement_score":0.7177316,"about_ca_system_score_codex":0.00005206163,"about_ca_system_score_gemma":0.00028003435,"threshold_uncertainty_score":0.9999124},"labels":[],"label_agreement":null},{"id":"W1523878115","doi":"10.1038/nbt.3231","title":"Oversight of human inheritable genome modification","year":2015,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"","keywords":"Human genome; Genome; Computational biology; Biology; Genetics; Gene","score_opus":0.010424062996771104,"score_gpt":0.29444617432910664,"score_spread":0.2840221113323355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1523878115","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14190727,0.13864626,0.013768369,0.67954904,0.0045675887,0.0026979449,0.0012452471,0.0007220072,0.016896272],"genre_scores_gemma":[0.8257875,0.0018438303,0.005466097,0.13000193,0.008496534,0.000105038765,0.011775949,0.00039037594,0.016132751],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988212,0.00002167071,0.0002321839,0.00047542588,0.00016587485,0.00028366086],"domain_scores_gemma":[0.99887,0.0000044668514,0.00014539945,0.0008193266,0.00013258231,0.000028236986],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00009917094,0.00024818082,0.00029357217,0.00019393885,0.000031917047,0.0000069402026,0.0004813033,0.0069064256,0.000017710365],"category_scores_gemma":[0.000058007343,0.00025580468,0.000101160884,0.00014822348,0.00012688166,0.0000014078528,0.00018118146,0.0016718055,0.000007846756],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000047308317,0.000009851391,0.0000055879677,0.00005615229,0.000050363236,0.0000074317672,0.000004716135,0.000014961631,0.6178759,0.00008774477,0.38173768,0.0001448739],"study_design_scores_gemma":[0.0001547932,0.00015238955,0.000022166527,0.000008739127,0.00002324842,0.00001497063,0.0000058739524,0.000004070208,0.31403363,0.000119449825,0.68527913,0.00018150616],"about_ca_topic_score_codex":0.000010343584,"about_ca_topic_score_gemma":0.0000055399782,"teacher_disagreement_score":0.6838802,"about_ca_system_score_codex":0.000030869833,"about_ca_system_score_gemma":0.00006698977,"threshold_uncertainty_score":0.9999894},"labels":[],"label_agreement":null},{"id":"W1532670577","doi":"10.1038/75452","title":"Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2","year":2000,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Coalition for Research in Women's Health; University of Toronto","funders":"National Cancer Institute","keywords":"Frameshift mutation; Amplicon; Biology; Oligonucleotide; Genetics; Multiplex; Polymerase chain reaction; Multiplex polymerase chain reaction; Molecular biology; Context (archaeology); Population; DNA sequencing; Multiplex ligation-dependent probe amplification; Mutation; DNA; Gene; Exon","score_opus":0.002464149416619745,"score_gpt":0.2231205657012266,"score_spread":0.22065641628460686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1532670577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935884,0.0029298582,0.0027757334,0.00043198068,0.00003633129,0.00007926993,0.0000061620935,0.000017388584,0.0001348716],"genre_scores_gemma":[0.9975874,0.0013469983,0.0009160106,0.000042937107,0.000020120524,0.0000034509371,0.000008047062,0.000006820109,0.00006823209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995886,0.000009550649,0.000086450826,0.00018755268,0.000023042667,0.000104804145],"domain_scores_gemma":[0.99980575,0.0000048307907,0.000015777552,0.00013785866,0.000014215407,0.000021569243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003844053,0.00007224395,0.00008006204,0.00010356861,0.000025554666,0.0000028403183,0.00005552901,0.0006443557,0.000006063157],"category_scores_gemma":[0.000026780106,0.00007651582,0.000016388953,0.00012470795,0.000092941045,0.0000015078866,0.000024102455,0.00021947367,4.98259e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019188947,0.000014388996,0.00035931365,0.000008123717,0.000009983853,9.861415e-7,0.000023576173,0.000032354354,0.97247577,0.00014149552,0.0000076123483,0.026907196],"study_design_scores_gemma":[0.00036841282,0.00015042465,0.012059665,0.000008255672,0.000008648216,0.000044425036,0.000054304,0.000078977944,0.9592898,0.000098665725,0.027745547,0.00009286584],"about_ca_topic_score_codex":0.000021982116,"about_ca_topic_score_gemma":0.0003292888,"teacher_disagreement_score":0.027737934,"about_ca_system_score_codex":0.0000062256636,"about_ca_system_score_gemma":0.000010275457,"threshold_uncertainty_score":0.49698615},"labels":[],"label_agreement":null},{"id":"W1547279309","doi":"10.1034/j.1399-0004.2000.570307.x","title":"A rapid fluorescent multiplexed‐PCR analysis (FMPA) for founder mutations in the <i>BRCA</i>1 and <i>BRCA</i>2 genes","year":2000,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame; McGill University; Coalition for Research in Women's Health; Jewish General Hospital; University of Toronto","funders":"","keywords":"Frameshift mutation; Genetics; Biology; Gene; Mutation; Population; Buccal swab; COLD-PCR; Heteroduplex; Point mutation; Medicine","score_opus":0.03479603682868758,"score_gpt":0.37666661043440397,"score_spread":0.3418705736057164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1547279309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9790731,0.00904898,0.010487605,0.0004130197,0.0001302863,0.00055853603,0.000050582355,0.000013474787,0.00022439013],"genre_scores_gemma":[0.98290175,0.0069723288,0.008324656,0.0008806195,0.00041075447,0.00009054085,0.00016068226,0.000027549075,0.00023112945],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99841136,0.000114249415,0.0005467259,0.00047523843,0.00013570469,0.00031671138],"domain_scores_gemma":[0.9991345,0.00020198344,0.000056000332,0.00043379847,0.00006293966,0.000110798675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054649625,0.00019415758,0.00027202695,0.00005904277,0.00009921363,0.000050278737,0.00026010082,0.00020323145,0.000037471575],"category_scores_gemma":[0.00012424243,0.00015915408,0.00028007783,0.00026627554,0.00016343583,0.000002353335,0.000052029463,0.00013092873,0.0000054431753],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049656717,0.0011983449,0.13880442,0.00013255714,0.0017510889,0.000015520862,0.0009657006,0.05962459,0.082534015,0.00011286542,0.005623261,0.70874107],"study_design_scores_gemma":[0.0055784406,0.0014443459,0.43125513,0.000025155798,0.001597282,0.000028556324,0.0006197483,0.04399377,0.024382388,0.00050030526,0.48943788,0.0011370011],"about_ca_topic_score_codex":0.000008947583,"about_ca_topic_score_gemma":0.00019737214,"teacher_disagreement_score":0.70760405,"about_ca_system_score_codex":0.000005957896,"about_ca_system_score_gemma":0.000040477276,"threshold_uncertainty_score":0.6490115},"labels":[],"label_agreement":null},{"id":"W1560326776","doi":"10.1038/nbt.3227","title":"CRISPR germline engineering—the community speaks","year":2015,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":143,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; Francis Crick Institute","keywords":"CRISPR; Germline; Gene engineering; Biology; Ethical issues; Genome editing; Engineering ethics; Biotechnology; Computational biology; Genetics; Environmental ethics; Engineering; Gene; Philosophy","score_opus":0.008692604092927473,"score_gpt":0.29600580292812484,"score_spread":0.28731319883519735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1560326776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9531105,0.009824025,0.028986862,0.005292681,0.0012095744,0.00026699435,0.000019738218,0.00024216254,0.001047435],"genre_scores_gemma":[0.9966533,0.000091137365,0.0021050524,0.00045133854,0.00029399185,0.000010833942,0.000044948254,0.000025995918,0.00032335793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927497,0.000036170255,0.00013834448,0.00019308415,0.00009921006,0.00025820005],"domain_scores_gemma":[0.99903715,0.00001601681,0.000032801865,0.0007750663,0.00006696668,0.0000719911],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030731855,0.00016195503,0.00012540906,0.00006577833,0.0000699697,0.000012558682,0.00051006436,0.0010118737,0.0000062229315],"category_scores_gemma":[0.00044298085,0.00012670874,0.0000600286,0.00017218747,0.00009315058,0.0000015333856,0.00027518685,0.0012029327,0.000018998933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005277161,0.0000882063,0.0003855099,0.000024611352,0.00009614664,0.000010271051,0.000098134915,0.0014486213,0.95384675,0.0028295848,0.035456974,0.0056623924],"study_design_scores_gemma":[0.00030719917,0.0001789826,0.00062631123,0.000004486652,0.0000115944185,0.00008121853,0.00010002034,0.00025888527,0.54179263,0.000105968626,0.45637074,0.0001619532],"about_ca_topic_score_codex":0.000018786697,"about_ca_topic_score_gemma":0.00004012724,"teacher_disagreement_score":0.42091376,"about_ca_system_score_codex":0.000014864633,"about_ca_system_score_gemma":0.0000330863,"threshold_uncertainty_score":0.7804496},"labels":[],"label_agreement":null},{"id":"W1563923385","doi":"","title":"High-Efficiency Thermal Asymmetric InterLaced (HE-TAIL) PCR for Amplification of Ds Transposon Insertion Sites in Barley","year":2010,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Transposable element; Biology; Genome; Genetics; genomic DNA; Multiple displacement amplification; Polymerase chain reaction; DNA; Molecular biology; Computational biology; Gene; DNA extraction","score_opus":0.007844531036369583,"score_gpt":0.2736301603358195,"score_spread":0.26578562929944993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1563923385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88149524,0.0001043557,0.11776868,0.000060562612,0.00013962017,0.00018814937,0.000007812866,0.000009363386,0.0002262012],"genre_scores_gemma":[0.99530274,0.00002062374,0.0043430724,0.000018762317,0.000065468485,0.000029898738,0.000099665864,0.000012989148,0.00010680334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993847,0.00001046191,0.00020751891,0.00019683554,0.000060136324,0.00014032116],"domain_scores_gemma":[0.99965954,0.000022198168,0.000037846174,0.00019080094,0.000058452482,0.00003115187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015355035,0.000092653354,0.00009908829,0.000108308,0.000017142595,0.000007680274,0.000117016105,0.00012430521,0.000019155057],"category_scores_gemma":[0.000085629836,0.00008565389,0.000058200523,0.00015956981,0.000022370263,0.0000031816746,0.000012591167,0.00006565029,0.0000015024042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005375408,0.000068907815,0.0030494053,0.00002604725,0.000007740635,6.3390225e-8,0.000041946438,0.00064114545,0.99019825,0.00044207112,0.000027197326,0.005443461],"study_design_scores_gemma":[0.00051882735,0.00021619789,0.052910242,0.0000047229582,0.00000899634,7.927407e-7,0.00003596289,0.001728436,0.94408643,0.00003105078,0.00035253805,0.00010580338],"about_ca_topic_score_codex":0.00004027774,"about_ca_topic_score_gemma":0.00018079109,"teacher_disagreement_score":0.11380746,"about_ca_system_score_codex":0.0000047423337,"about_ca_system_score_gemma":0.000016609105,"threshold_uncertainty_score":0.3492864},"labels":[],"label_agreement":null},{"id":"W1567684706","doi":"10.1002/9781118384947.ch2","title":"Concepts and Tools for Recombinant DNA Technology","year":2014,"lang":"en","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Recombinant DNA; Oligonucleotide; DNA; Biology; DNA sequencing; In vitro recombination; Cloning (programming); Polymerase chain reaction; Computational biology; Gene; Molecular cloning; Sequencing by ligation; Plasmid; Applications of PCR; Genetics; Molecular biology; Complementary DNA; Genomic library; Multiplex polymerase chain reaction; Base sequence; Computer science","score_opus":0.0066509412538214435,"score_gpt":0.30313308869328776,"score_spread":0.2964821474394663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1567684706","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004061588,0.017637212,0.33435798,0.000713533,0.0018928854,0.0018584743,0.00008971684,0.0003359006,0.6390527],"genre_scores_gemma":[0.02690209,0.0012503918,0.010279145,0.00019595417,0.0005524484,0.00013126084,0.00021979978,0.00037530225,0.9600936],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99947023,0.0000041789817,0.00008499722,0.00026437323,0.000024974062,0.00015127203],"domain_scores_gemma":[0.9996791,0.0000071983577,0.000034248453,0.00023297998,0.000013548143,0.000032955064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000402879,0.0001427013,0.00015913603,0.00005935723,0.00001386748,0.000016923941,0.00008918193,0.00040181066,0.00009671243],"category_scores_gemma":[0.00005143927,0.00012864206,0.00003847625,0.000021487098,0.000047070844,3.6689403e-7,0.000057914793,0.000039532748,0.000007623467],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009346297,0.000013708534,0.00003445471,0.00013569732,0.00008861791,5.842834e-7,0.0000035139028,0.0000018893824,0.09715615,0.0013649027,0.84718513,0.054006007],"study_design_scores_gemma":[0.00032430192,0.0001610472,0.000008278881,0.000024867659,0.000013553478,0.0000073906517,0.000015861126,0.000013510177,0.047097713,0.00006754776,0.9520861,0.00017985227],"about_ca_topic_score_codex":0.0000034770658,"about_ca_topic_score_gemma":0.000034437966,"teacher_disagreement_score":0.32407883,"about_ca_system_score_codex":0.000001973427,"about_ca_system_score_gemma":0.000011916786,"threshold_uncertainty_score":0.5245871},"labels":[],"label_agreement":null},{"id":"W1577746698","doi":"10.1016/j.cell.2015.06.037","title":"Natural Variation in Gene Expression Modulates the Severity of Mutant Phenotypes","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Phenotype; Mutant; Gene; Genetics; Gene expression; Variation (astronomy)","score_opus":0.006463007406163166,"score_gpt":0.24392035797926687,"score_spread":0.2374573505731037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1577746698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947504,0.0010898605,0.003735289,0.00002202895,0.0001227796,0.00005185081,0.0000020280654,0.0000026204054,0.00022318431],"genre_scores_gemma":[0.99888617,0.00002382304,0.0009193586,0.0000143771595,0.000056848537,0.000002320605,0.00001219637,0.00000457079,0.00008031795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997121,0.000015552301,0.000073905045,0.00008562188,0.00004817313,0.000064624],"domain_scores_gemma":[0.9998011,0.00000399666,0.000021160236,0.00013082489,0.00002561615,0.000017276267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087203065,0.000044169225,0.00004413168,0.000009801049,0.000008718354,0.0000031752402,0.00006663306,0.00003889147,0.0000018920632],"category_scores_gemma":[0.000021190466,0.00003172736,0.000016858054,0.000031639112,0.000010850128,0.0000011316708,0.000038696136,0.00003452162,0.0000010531712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014359609,0.000013846285,0.00040212407,0.0000059627255,0.0000017941516,2.797429e-7,0.00019006498,0.0041682357,0.99498665,0.0000026933749,0.00006038998,0.00015359056],"study_design_scores_gemma":[0.00019360741,0.000022178783,0.008453147,0.000003278166,0.0000024583176,0.0000013219018,0.000040357172,0.0020603612,0.98877245,0.00008135263,0.0003261067,0.00004337507],"about_ca_topic_score_codex":0.00002129075,"about_ca_topic_score_gemma":0.0000074843065,"teacher_disagreement_score":0.008051023,"about_ca_system_score_codex":0.000004408572,"about_ca_system_score_gemma":0.000017751483,"threshold_uncertainty_score":0.12938042},"labels":[],"label_agreement":null},{"id":"W1585879834","doi":"10.1128/microbiolspec.mdna3-0023-2014","title":"Hairpin Telomere Resolvases","year":2014,"lang":"en","type":"review","venue":"Microbiology Spectrum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Telomere; Recombinase; Telomere-binding protein; DNA; Biology; DNA replication; Active site; Genetics; Enzyme; Chemistry; Biochemistry; Recombination; Gene; DNA-binding protein; Transcription factor","score_opus":0.011057662661959804,"score_gpt":0.3224273272770194,"score_spread":0.3113696646150596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1585879834","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000021682798,0.99644834,0.00091467437,0.000035114183,0.0006152646,0.0003099606,0.00012367892,0.00004154208,0.0014897495],"genre_scores_gemma":[0.00008623486,0.9949634,0.00035086786,0.00009975593,0.0009805514,0.000045187076,0.0013630559,0.000092575654,0.0020183676],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99814695,0.00012447228,0.00045038314,0.0007268019,0.000030476082,0.00052094023],"domain_scores_gemma":[0.99896014,0.00002715574,0.00015689149,0.000754211,0.000016191323,0.000085440246],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001590984,0.0005179209,0.001113014,0.00012609002,0.00007194401,0.000019794132,0.00046876923,0.000788372,0.00008901929],"category_scores_gemma":[0.00004865687,0.00044763734,0.00052644836,0.00011013678,0.00012540795,7.420998e-7,0.00025086844,0.0003018358,0.00028770222],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034066587,0.00013644992,0.00002243459,0.013204284,0.0013919075,0.00004928111,0.000020400019,0.00003008146,0.029580433,0.0007999327,0.12064464,0.8340861],"study_design_scores_gemma":[0.00013115507,0.00016889567,7.383499e-7,0.00066525186,0.00017663841,0.00040992867,0.0000023416878,5.001552e-7,0.002922659,0.000018900711,0.9950046,0.0004984115],"about_ca_topic_score_codex":0.0000073409938,"about_ca_topic_score_gemma":0.00004744766,"teacher_disagreement_score":0.87435997,"about_ca_system_score_codex":0.000027870994,"about_ca_system_score_gemma":0.00011408725,"threshold_uncertainty_score":0.9997975},"labels":[],"label_agreement":null},{"id":"W1603695074","doi":"10.1016/s0076-6879(06)20008-9","title":"Gene Trapping in Embryonic Stem Cells","year":2006,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Insertional mutagenesis; Mutagenesis; Gene; Biology; Embryonic stem cell; Genetics; Genome; Computational biology; Gene targeting; Function (biology); Mutation","score_opus":0.025535812039891213,"score_gpt":0.39355709607270956,"score_spread":0.36802128403281836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1603695074","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72912097,0.0048515475,0.26080334,0.00024367604,0.001929809,0.000632643,0.000014667505,0.000060939874,0.0023423964],"genre_scores_gemma":[0.32175967,0.0003510885,0.67569363,0.00053208735,0.00034599716,0.00023657276,0.000038163707,0.000119257704,0.00092352956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9897053,0.00546935,0.0014207888,0.0016740165,0.0001836756,0.0015468169],"domain_scores_gemma":[0.9971352,0.0012346844,0.00026406723,0.0011604199,0.00006463313,0.00014097591],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.006445294,0.00074382295,0.0012759998,0.0011209798,0.0000782361,0.000023288678,0.0008281379,0.0015111441,0.000078067984],"category_scores_gemma":[0.00040895876,0.00082720036,0.00026353932,0.00094652915,0.00038636607,0.000011464183,0.0003543148,0.0012170451,0.00001744372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023249492,0.00036800798,0.004216666,0.000054405482,0.000041456788,0.00023113436,0.00015916758,0.020800596,0.93831927,0.0007673176,0.00031668335,0.034492817],"study_design_scores_gemma":[0.0030093412,0.0009429873,0.06787572,0.000066324676,0.000031421303,0.00034650502,0.00019668273,0.0006504321,0.9084317,0.004294014,0.013086993,0.0010678438],"about_ca_topic_score_codex":0.00035548772,"about_ca_topic_score_gemma":0.0019851932,"teacher_disagreement_score":0.41489032,"about_ca_system_score_codex":0.00020747447,"about_ca_system_score_gemma":0.0001482489,"threshold_uncertainty_score":0.9997851},"labels":[],"label_agreement":null},{"id":"W1612113724","doi":"10.1002/0471142301.ns0122s70","title":"Non‐isotopic RNA In Situ Hybridization on Embryonic Sections","year":2015,"lang":"en","type":"article","venue":"Current Protocols in Neuroscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; Montreal Clinical Research Institute; University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"In situ hybridization; In situ; Embryonic stem cell; RNA; Biology; Chemistry; Cell biology; Molecular biology; Genetics; Messenger RNA; Gene","score_opus":0.04676839852886611,"score_gpt":0.39204179167086023,"score_spread":0.3452733931419941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1612113724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97445786,0.000056982557,0.009670852,0.000060882892,0.00067688944,0.013614416,0.0000023152206,0.000016023212,0.0014437778],"genre_scores_gemma":[0.98978245,0.000014051157,0.00004667904,0.000055942364,0.00007970333,0.00987945,0.0000041629996,0.000008266779,0.00012927744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991668,0.00002571761,0.0001431626,0.00033060083,0.00013391013,0.00019982998],"domain_scores_gemma":[0.999642,0.0000035699018,0.000030713454,0.00023069771,0.000025523359,0.00006747553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016568278,0.00009576196,0.000072897616,0.00009206289,0.000022730195,0.000027557411,0.00019349574,0.000035761554,6.6315897e-7],"category_scores_gemma":[0.00015495563,0.00009737398,0.000021331201,0.0003055704,0.000037859023,0.0000070869364,0.000072143506,0.00012405177,0.0000041887524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024148885,0.00021024862,0.012239487,0.000038578226,3.103491e-7,0.0000037903299,0.00007169782,0.025988616,0.9564424,0.000068635,0.00036630532,0.004545752],"study_design_scores_gemma":[0.0017352375,0.0008827026,0.107681245,0.0002059649,0.0000017828459,0.000012767949,0.00003087396,0.0062061306,0.77699465,0.000075417745,0.10578305,0.000390156],"about_ca_topic_score_codex":0.0000019444246,"about_ca_topic_score_gemma":0.000030014133,"teacher_disagreement_score":0.17944777,"about_ca_system_score_codex":0.000028079843,"about_ca_system_score_gemma":0.0000877077,"threshold_uncertainty_score":0.39707956},"labels":[],"label_agreement":null},{"id":"W1653026469","doi":"10.1071/rdv17n2ab46","title":"46 EFFICIENT TRANSFECTION OF PLASMID DNA INTO CELLS FOR USE AS NUCLEAR DONORS","year":2004,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Transfection; Electroporation; Molecular biology; Somatic cell nuclear transfer; Plasmid; Recombinant DNA; Cell culture; Green fluorescent protein; Biology; Fluorescence microscope; Chemistry; Andrology; DNA; Gene; Fluorescence; Genetics; Medicine; Embryogenesis","score_opus":0.009993008502002214,"score_gpt":0.2557049464989746,"score_spread":0.24571193799697236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1653026469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9654578,0.00015100976,0.033809993,0.00007139301,0.00021828755,0.00025797563,0.0000021389076,0.00001413278,0.000017295797],"genre_scores_gemma":[0.9918054,0.0000592795,0.007997065,0.00001793151,0.000031910597,0.00001426419,0.000018521874,0.000009589075,0.000046068883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999265,0.000008812908,0.00019033182,0.00036078927,0.00007070515,0.00010435269],"domain_scores_gemma":[0.9996757,0.0000038125795,0.000027224412,0.00018493594,0.000063465115,0.00004489265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018210216,0.000089882255,0.00009037467,0.00003194106,0.00008443428,0.000010845208,0.00003155294,0.00006659269,0.0000040606583],"category_scores_gemma":[0.000041224488,0.00009089887,0.000036193258,0.00004456303,0.000035976638,0.0000034791174,0.00002047218,0.000030998322,0.0000021147232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041125334,0.00012757037,0.00022041606,0.00012223874,0.000033905762,1.4096194e-7,0.0008297072,0.011442783,0.9801665,0.000019072482,0.000029593864,0.0065968055],"study_design_scores_gemma":[0.00046149036,0.00013947954,0.012388808,0.000011275344,0.000007671708,0.000003889467,0.00010059026,0.000037148297,0.969608,0.000031096966,0.017106872,0.00010366383],"about_ca_topic_score_codex":0.000030634892,"about_ca_topic_score_gemma":0.000016766495,"teacher_disagreement_score":0.026347596,"about_ca_system_score_codex":0.000027258418,"about_ca_system_score_gemma":0.00005115391,"threshold_uncertainty_score":0.37067485},"labels":[],"label_agreement":null},{"id":"W169680034","doi":"10.1007/978-3-642-04809-8_3","title":"Gene Transfer Methods","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Biology; Mendelian inheritance; Genetics; Introgression; Gene; Genetic variation; Gene mapping; Hybrid; Chromosome; Botany","score_opus":0.012027559931934271,"score_gpt":0.32808422278338295,"score_spread":0.3160566628514487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W169680034","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019004407,0.0018464787,0.37273854,0.000036086432,0.0004262233,0.00012945259,0.000021187016,0.000025176354,0.6245868],"genre_scores_gemma":[0.0020776917,0.00082507683,0.09319891,0.0002242127,0.0008052197,0.000008539068,0.00021084485,0.00010690293,0.9025426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924785,0.0000058685164,0.00016761346,0.000342676,0.00007534589,0.0001606333],"domain_scores_gemma":[0.99941534,0.0000061770293,0.000013244365,0.00043875218,0.00004088735,0.00008562448],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011357334,0.0002504706,0.00018548804,0.000038455844,0.000027342972,0.000011721298,0.00015830199,0.0006574807,0.0008704477],"category_scores_gemma":[0.000007700138,0.0002361253,0.00018538718,0.0000059685412,0.000042843087,3.6871185e-7,0.000051356976,0.00024969756,0.000040593393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007159405,0.0000037666632,6.6175886e-7,0.000014369268,0.00007545158,0.0000023516689,0.0000063182138,0.000009531523,0.9682902,0.002562141,0.0006424801,0.028385557],"study_design_scores_gemma":[0.00007129245,0.00003529911,0.0000025616264,0.0000032555736,0.00002374087,0.000013452296,5.1290795e-7,0.0000030201952,0.50233775,0.00036621836,0.4969621,0.00018077117],"about_ca_topic_score_codex":0.0000027609478,"about_ca_topic_score_gemma":0.00002514842,"teacher_disagreement_score":0.49631962,"about_ca_system_score_codex":0.0000034431807,"about_ca_system_score_gemma":0.000033347413,"threshold_uncertainty_score":0.962891},"labels":[],"label_agreement":null},{"id":"W1714206796","doi":"10.3389/fgene.2015.00293","title":"Efficacy of the porcine species in biomedical research","year":2015,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Ste. Anne's Hospital","funders":"Ciência sem Fronteiras; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Domestication; Biology; Transgenesis; Cloning (programming); Computational biology; Somatic cell; Genome editing; Somatic cell nuclear transfer; Biotechnology; Genome; Bioinformatics; Genetics; Reproductive technology; Computer science; Gene; Blastocyst","score_opus":0.03479789215171608,"score_gpt":0.3534591695067187,"score_spread":0.3186612773550026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1714206796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884885,0.004784943,0.0046971827,0.00023057348,0.0007006187,0.0001873011,0.0000051589473,0.0000024640815,0.00090328377],"genre_scores_gemma":[0.9937913,0.00033466992,0.005170775,0.000019606056,0.00015468788,0.000005985137,0.000011082714,0.000013040887,0.00049888017],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99901175,0.00007826222,0.00021945742,0.00018106427,0.00026386994,0.00024559954],"domain_scores_gemma":[0.99948174,0.0000105673225,0.000023815726,0.00035438722,0.00006071916,0.00006878372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005086709,0.00007935936,0.00012186893,0.00012579553,0.000013980328,0.00000538492,0.00031033545,0.00011726558,0.0000028347022],"category_scores_gemma":[0.00026544303,0.00006438091,0.00003666438,0.00037461138,0.0002042601,7.5089e-7,0.00019005899,0.00015761128,9.416065e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022157667,0.00033950177,0.649746,0.00005310042,0.00003659011,0.000011206195,0.0010413501,0.01096628,0.2340257,0.000060164402,0.09479463,0.008703912],"study_design_scores_gemma":[0.0033274435,0.00045396687,0.4455909,0.00007502999,0.000009816299,0.0000085182255,0.0015729691,0.0021730764,0.3525769,0.00048399295,0.19344671,0.0002806493],"about_ca_topic_score_codex":0.000014377462,"about_ca_topic_score_gemma":0.000037318514,"teacher_disagreement_score":0.20415509,"about_ca_system_score_codex":0.000028886603,"about_ca_system_score_gemma":0.000110372064,"threshold_uncertainty_score":0.26253775},"labels":[],"label_agreement":null},{"id":"W1740564681","doi":"10.1016/j.celrep.2015.05.045","title":"Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health; Alberta Innovates; Alberta Innovates - Health Solutions; Universitair Medisch Centrum Groningen; National Institute of Allergy and Infectious Diseases; European Commission; Crohn's and Colitis Foundation; Wellcome Trust; Leona M. and Harry B. Helmsley Charitable Trust; Crohn's and Colitis Foundation of America","keywords":"Autophagy; ATG16L1; Ubiquitin ligase; Biology; Ubiquitin; Allele; Functional genomics; Cell biology; Genetics; Genomics; Gene; Genome","score_opus":0.007277653453890835,"score_gpt":0.25398804785411977,"score_spread":0.24671039440022893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1740564681","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98999053,0.000943806,0.008102099,0.0000043306245,0.00049731333,0.0002288221,0.00003503393,0.000008027947,0.00019000405],"genre_scores_gemma":[0.9980723,0.00007601396,0.0011645021,0.0000075761186,0.00012354496,0.000020059735,0.00015704783,0.00001936399,0.0003595383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991838,0.000018871464,0.00031965048,0.00025530398,0.00006417792,0.00015820861],"domain_scores_gemma":[0.99936074,0.000005928053,0.00013442972,0.0003042555,0.000086206244,0.000108450055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024804188,0.00010610631,0.0001425735,0.000042279567,0.000015698637,0.000016799611,0.00006710516,0.000077967525,0.0000048880206],"category_scores_gemma":[0.00019158353,0.0001057685,0.00007226138,0.000048487633,0.000025606754,0.0000026851349,0.000054541622,0.000042361695,6.3290076e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026166564,0.0000937365,0.003953936,0.00004987064,0.000020800811,0.00017987068,0.000168274,0.0028164876,0.99101216,0.000003697405,0.0006073576,0.000832166],"study_design_scores_gemma":[0.0006135523,0.000092875955,0.030182436,0.000014414181,0.000040798393,0.00002862112,0.00012376835,0.001283148,0.9506769,0.000334248,0.016423628,0.00018559616],"about_ca_topic_score_codex":0.00009305789,"about_ca_topic_score_gemma":0.00004318885,"teacher_disagreement_score":0.040335223,"about_ca_system_score_codex":0.000016863418,"about_ca_system_score_gemma":0.00018783729,"threshold_uncertainty_score":0.43131143},"labels":[],"label_agreement":null},{"id":"W1751510803","doi":"10.1038/nmeth.3580","title":"Cas9 gRNA engineering for genome editing, activation and repression","year":2015,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":356,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Human Genome Research Institute; University of California, San Diego; National Cancer Institute; National Institutes of Health; Broad Institute; Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University; U.S. Department of Energy","keywords":"Guide RNA; Cas9; CRISPR; Genome editing; Nuclease; Computational biology; RNA editing; Biology; Psychological repression; RNA; Genome engineering; Genome; Genetics; Cell biology; Gene; Gene expression","score_opus":0.015958692495306914,"score_gpt":0.4075014387992125,"score_spread":0.3915427463039056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1751510803","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09826953,0.0033340692,0.8974327,0.00009464568,0.00046215742,0.00015022681,0.0000048157863,0.000020508518,0.00023134741],"genre_scores_gemma":[0.5144603,0.00003537521,0.48407802,0.00008957797,0.0010174611,0.000024808827,0.00005576055,0.000024233503,0.0002144271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999507,0.000024194982,0.00008587173,0.00020413636,0.000055301312,0.00012349559],"domain_scores_gemma":[0.99965155,0.000027071721,0.000028327035,0.00015411148,0.000065919456,0.00007304152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046178765,0.00009009852,0.000083778745,0.00003167175,0.000024904404,0.000013106564,0.000055913817,0.00024273862,0.0000010892786],"category_scores_gemma":[0.0007514483,0.00008443835,0.000030375078,0.000042094234,0.0000074412956,0.0000028294173,0.000048784434,0.00013327635,1.47554e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019157427,0.000004314708,0.000059651196,0.000024609071,0.000013536515,2.584127e-7,0.000055635086,0.0014989591,0.9865194,0.00004738118,0.0006310597,0.011126037],"study_design_scores_gemma":[0.00032381676,0.00007547334,0.0010342725,0.0000109368475,0.000010523857,0.000010981277,0.000032044183,0.0026188742,0.80907255,0.000078860125,0.18661475,0.000116927666],"about_ca_topic_score_codex":0.0000017378137,"about_ca_topic_score_gemma":4.8270505e-7,"teacher_disagreement_score":0.4161908,"about_ca_system_score_codex":0.000008991508,"about_ca_system_score_gemma":0.00001350507,"threshold_uncertainty_score":0.3443296},"labels":[],"label_agreement":null},{"id":"W176120309","doi":"10.1007/978-3-540-75157-1_2","title":"RNAi Pathway in C. elegans: The Argonautes and Collaborators","year":2007,"lang":"en","type":"review","venue":"Current topics in microbiology and immunology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"","keywords":"Caenorhabditis elegans; RNA interference; Argonaute; Biology; Gene silencing; Gene; Computational biology; Genetics; Model organism; RNA","score_opus":0.018419022569554452,"score_gpt":0.3379384525237682,"score_spread":0.31951942995421373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W176120309","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0081839515,0.9904948,0.00006286059,0.000035841593,0.0008027445,0.00032563225,0.000036365233,0.0000047969825,0.00005299087],"genre_scores_gemma":[0.0009580099,0.9984881,0.00004354668,0.00003648288,0.00015197943,0.00004048356,0.00019058664,0.000017380502,0.00007342503],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986358,0.00016808143,0.0004202313,0.00042117015,0.000014893603,0.00033980195],"domain_scores_gemma":[0.9995284,0.000063975705,0.00009125272,0.00027085788,0.000022585788,0.000022900045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029566593,0.00029116124,0.0005962402,0.00015713886,0.0000471908,0.0000117990485,0.00022128546,0.0006427955,0.000004536618],"category_scores_gemma":[0.00007010281,0.00021677047,0.000064580745,0.000171178,0.000302817,0.0000019562585,0.00023799068,0.0005557816,0.0000023896807],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013221904,0.00004532592,0.00037100064,0.0009630315,0.00008059173,0.00000862673,0.0000794758,9.814194e-7,0.00252089,0.00070258864,0.00019448547,0.9950198],"study_design_scores_gemma":[0.00026070437,0.00007753859,0.00013631933,0.00044938127,0.000021409784,0.0001490307,0.000033964363,5.243068e-7,0.00053414336,0.000032388572,0.9980793,0.00022527485],"about_ca_topic_score_codex":0.0000043765403,"about_ca_topic_score_gemma":0.00011916599,"teacher_disagreement_score":0.9978848,"about_ca_system_score_codex":0.000017065571,"about_ca_system_score_gemma":0.00009289629,"threshold_uncertainty_score":0.8839643},"labels":[],"label_agreement":null},{"id":"W1762471142","doi":"10.1002/9780470015902.a0020834.pub2","title":"Biased Gene Conversion and Its Impact on Genome Evolution","year":2014,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Gene conversion; Allele; Genetics; Biology; Mendelian inheritance; Gene; Population; Genome; Homologous recombination","score_opus":0.006993441630664113,"score_gpt":0.2843261490096527,"score_spread":0.2773327073789886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1762471142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5971683,0.035312172,0.0027678667,0.000085985164,0.0011562281,0.0005455119,0.00018310417,0.000055000393,0.36272582],"genre_scores_gemma":[0.9491562,0.007300466,0.00046956903,0.00006550566,0.0009170202,0.0000063839757,0.000063423155,0.00008463901,0.041936774],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99918956,0.000026187443,0.00013000367,0.00031695346,0.00017022093,0.00016706264],"domain_scores_gemma":[0.99961084,0.000012952762,0.00010694086,0.00015297899,0.00001771982,0.00009855914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017848948,0.00016455821,0.00017681632,0.00013559514,0.00003705791,0.0000061227574,0.00017170154,0.00016119122,0.00013148024],"category_scores_gemma":[0.00008435747,0.00013015395,0.00005814414,0.000090225134,0.00010774327,0.0000015590712,0.000055871013,0.000048752543,0.000016985396],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016282214,0.00018692938,0.009789186,0.000681143,0.00030718764,0.0000045787215,0.00017855079,0.008757543,0.7241309,0.00020987606,0.25370565,0.001885627],"study_design_scores_gemma":[0.0014751808,0.0033261967,0.03500567,0.000263733,0.00009887086,0.0000136524695,0.000096083066,0.0015992901,0.0362214,0.00003905756,0.9204675,0.0013933791],"about_ca_topic_score_codex":0.00004068686,"about_ca_topic_score_gemma":0.0000075405424,"teacher_disagreement_score":0.6879095,"about_ca_system_score_codex":0.000006830622,"about_ca_system_score_gemma":0.00010074484,"threshold_uncertainty_score":0.53075236},"labels":[],"label_agreement":null},{"id":"W1765280136","doi":"10.5376/mpb.2015.06.0012","title":"Transformation and Transgenic Expression studies of Glyphosate tolerant and Cane Borer Resistance Genes in Sugarcane (&lt;i&gt;Sccharum officinarum&lt;/i&gt; L.)","year":2015,"lang":"en","type":"article","venue":"Molecular Plant Breeding","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Transformation (genetics); Saccharum officinarum; Glyphosate; Genetically modified crops; Transgene; Gene; Cane; Biotechnology; Herbicide resistance; Genetics; Resistance (ecology); Botany; Agronomy","score_opus":0.017839753506299474,"score_gpt":0.26623313720852887,"score_spread":0.2483933837022294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1765280136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95418674,0.040877644,0.004286094,0.0001614496,0.0000831408,0.00020389612,0.00005566993,0.000010862097,0.00013451456],"genre_scores_gemma":[0.9968399,0.0020866655,0.0008702512,0.000027440276,0.000037519858,0.000014875863,0.00006775958,0.000020907872,0.00003471019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989085,0.000033333694,0.00031768944,0.00029911948,0.0001848706,0.00025647628],"domain_scores_gemma":[0.9996031,0.000013064875,0.00006169049,0.00015731392,0.000062642575,0.0001021779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029047547,0.0001987596,0.0002731575,0.000101312144,0.000042888212,0.000014723662,0.00008935498,0.000112339476,8.4951887e-7],"category_scores_gemma":[0.00003218353,0.00019022504,0.00004066809,0.000094815645,0.00007146362,0.0000096080075,0.000046785462,0.00006774574,1.8910312e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019181374,0.000016576403,0.00015890422,0.00018012026,0.00003722465,0.000018076194,0.0012794422,0.00078794267,0.9962181,0.00010993865,0.00015736856,0.0008445351],"study_design_scores_gemma":[0.0013090963,0.00022020965,0.0012783551,0.00024199822,0.0000359777,0.000048672322,0.00045283683,0.00091380154,0.9907026,0.000038768183,0.0044930344,0.000264622],"about_ca_topic_score_codex":0.000020221367,"about_ca_topic_score_gemma":0.00041818444,"teacher_disagreement_score":0.042653143,"about_ca_system_score_codex":0.000017328888,"about_ca_system_score_gemma":0.000034953147,"threshold_uncertainty_score":0.7757152},"labels":[],"label_agreement":null},{"id":"W1789647333","doi":"10.1093/nar/gkv497","title":"Spring loading a pre-cleavage intermediate for hairpin telomere formation","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Biology; Telomere; Cleavage (geology); DNA; Tn3 transposon; Mutant; Cleavage factor; Telomere-binding protein; Biochemistry; DNA-binding protein; RNA","score_opus":0.04574419006803774,"score_gpt":0.3865079808129965,"score_spread":0.3407637907449587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1789647333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9492068,0.0008060181,0.045170553,0.00013072373,0.0001942622,0.0004997881,0.000011375194,0.000034175133,0.00394626],"genre_scores_gemma":[0.99622226,0.00006213359,0.0024673133,0.000027521175,0.00036846162,0.00007766151,0.000028771052,0.00003351011,0.00071237877],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998841,0.000045659508,0.00017046272,0.0002501959,0.00025965623,0.000433016],"domain_scores_gemma":[0.9993084,0.00002299111,0.000024240971,0.0002944824,0.00017918882,0.00017066722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008402037,0.00010521811,0.00010140784,0.00011220503,0.00009719649,0.000060782782,0.00025329797,0.00012013307,0.0000071420623],"category_scores_gemma":[0.0003875382,0.000105396066,0.000057630426,0.0001241874,0.000060385715,0.000011184989,0.00021450537,0.00016255649,0.00003568943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003560267,0.00006113538,0.0029107453,0.00021848672,0.00005208821,0.0000050148983,0.0011793098,0.000544852,0.93530005,0.0003919689,0.024278913,0.034701407],"study_design_scores_gemma":[0.0015174978,0.0008712332,0.004075594,0.000068807625,0.000009104005,0.000016046659,0.0009402292,0.01130579,0.83461887,0.00044531876,0.14581612,0.00031541917],"about_ca_topic_score_codex":0.000022934459,"about_ca_topic_score_gemma":0.00003193192,"teacher_disagreement_score":0.12153721,"about_ca_system_score_codex":0.00005137022,"about_ca_system_score_gemma":0.000060026803,"threshold_uncertainty_score":0.4297927},"labels":[],"label_agreement":null},{"id":"W1823719955","doi":"10.1098/rspb.2015.1270","title":"Costs of CRISPR-Cas-mediated resistance in<i>Streptococcus thermophilus</i>","year":2015,"lang":"en","type":"article","venue":"Proceedings of the Royal Society B Biological Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Wellcome Trust","keywords":"CRISPR; Biology; Streptococcus thermophilus; Acquired immune system; Immune system; Computational biology; Virulence; Genetics; Bacteria; Gene","score_opus":0.019029894391683455,"score_gpt":0.285768532186913,"score_spread":0.26673863779522955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1823719955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99430615,0.0010786118,0.00008573757,0.00021027935,0.00007402325,0.00016277684,0.000008090777,0.000007753697,0.0040666074],"genre_scores_gemma":[0.9988382,0.000078764446,0.00086333655,0.00007921479,0.000044645898,0.000011133167,0.0000015359282,0.000003625821,0.00007956264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991038,0.000009277546,0.00021741896,0.00025725106,0.00019511922,0.00021714279],"domain_scores_gemma":[0.99960154,0.000022753049,0.00012264772,0.00007113191,0.00012262476,0.00005927228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005974306,0.00010656372,0.00015157751,0.000009971857,0.000050175524,0.000010942907,0.0005051442,0.00013288326,0.0000042817524],"category_scores_gemma":[0.00036930863,0.000061862236,0.00012773353,0.00028325606,0.0005467455,0.0000036042957,0.00022331324,0.00008022056,6.657148e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004207524,0.000079950856,0.39901212,0.000028511487,0.000018187246,9.649237e-8,0.00034389316,0.00016642504,0.59643304,0.0005302999,0.0031373054,0.00020806404],"study_design_scores_gemma":[0.00075176806,0.0006084025,0.16817726,0.00009844789,0.000011983253,9.73719e-7,0.0019248774,0.0007773815,0.8238515,0.0014064189,0.0020729015,0.00031804998],"about_ca_topic_score_codex":0.00002483947,"about_ca_topic_score_gemma":0.0000054868337,"teacher_disagreement_score":0.23083487,"about_ca_system_score_codex":0.000019726362,"about_ca_system_score_gemma":0.000039650393,"threshold_uncertainty_score":0.25226688},"labels":[],"label_agreement":null},{"id":"W1843657066","doi":"10.1111/jeb.12683","title":"How mechanisms of habitat preference evolve and promote divergence with gene flow","year":2015,"lang":"en","type":"article","venue":"Journal of Evolutionary Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Tennessee, Knoxville; National Institute of General Medical Sciences; U.S. Department of Homeland Security; National Institute for Mathematical and Biological Synthesis; Universität Basel; U.S. Department of Agriculture; National Institutes of Health; National Science Foundation","keywords":"Biology; Gene flow; Divergence (linguistics); Preference; Habitat; Evolutionary biology; Ecology; Gene; Genetics; Genetic variation; Statistics","score_opus":0.016070261671395133,"score_gpt":0.2649400263281556,"score_spread":0.24886976465676047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1843657066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7355588,0.005449813,0.25840905,0.0002326182,0.00020327055,0.00007901346,0.000022346625,0.0000026500352,0.000042435637],"genre_scores_gemma":[0.9426632,0.00022105675,0.056902554,0.000015260242,0.00010948739,0.0000018444572,0.000013223343,0.000006647938,0.00006674725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994429,0.00003547172,0.00017049641,0.00013128058,0.000091532675,0.00012836262],"domain_scores_gemma":[0.999321,0.0000081149,0.00014790476,0.0001150739,0.00030649698,0.00010141707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014060373,0.0000979896,0.00016148173,0.00005068091,0.000021024527,0.000004343967,0.000121488105,0.00009677477,0.0000020932885],"category_scores_gemma":[0.00008275012,0.00007222844,0.00003965533,0.000053000826,0.000096258074,0.0000071015675,0.00007130525,0.00007389679,3.0290752e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027186374,0.000051863128,0.014473556,0.000019207504,0.000106932384,0.0000073681076,0.00005449666,0.000962388,0.9818707,0.00024528173,0.0008322316,0.0011041114],"study_design_scores_gemma":[0.0031676262,0.013866314,0.05938368,0.00010530744,0.00015124041,0.0024015354,0.00041397425,0.0026517636,0.89840364,0.010472112,0.008415842,0.0005669709],"about_ca_topic_score_codex":0.0000025903385,"about_ca_topic_score_gemma":0.000005772047,"teacher_disagreement_score":0.20710438,"about_ca_system_score_codex":0.000011602397,"about_ca_system_score_gemma":0.00010977711,"threshold_uncertainty_score":0.29453903},"labels":[],"label_agreement":null},{"id":"W1845753170","doi":"10.1002/9780470942390.mo140150","title":"Tissue‐Specific Regulation of Oncogene Expression Using Cre‐Inducible ROSA26 Knock‐In Transgenic Mice","year":2015,"lang":"en","type":"article","venue":"Current Protocols in Mouse Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute","keywords":"Cre recombinase; Gene knockin; Transgene; Biology; Recombinase; Genetically modified mouse; Germline; Transgenesis; Cre-Lox recombination; Gene targeting; Cell biology; Gene; Molecular biology; Genetics; Embryogenesis","score_opus":0.08461969845079864,"score_gpt":0.4366012588779673,"score_spread":0.35198156042716866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1845753170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96256626,0.0020682523,0.024409298,0.000008894985,0.0002640258,0.010585157,0.000019334493,0.000012555838,0.000066226654],"genre_scores_gemma":[0.99131465,0.00008502475,0.0035583698,0.0000043088367,0.00023608883,0.0046313456,0.000096936514,0.000027209113,0.000046095793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986702,0.0001258172,0.00043714867,0.00040682705,0.000084356696,0.00027562908],"domain_scores_gemma":[0.9994089,0.0000098755045,0.00010216434,0.0003402879,0.00006618592,0.00007258698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034523854,0.00017339675,0.00024420404,0.00013567686,0.000017298798,0.0000068311642,0.00020162627,0.00023415935,0.00001185317],"category_scores_gemma":[0.000046205478,0.00017227653,0.000050219893,0.00016051168,0.000058831276,0.0000061024293,0.000061404506,0.00012677045,0.0000023660148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014718459,0.0001378938,0.0035726523,0.00006462825,0.0000037344362,2.9634413e-7,0.00014428954,0.0040269652,0.98631465,0.000021880096,0.0001034168,0.0054623764],"study_design_scores_gemma":[0.0013507992,0.000271497,0.00056657696,0.00011209763,0.0000025466186,0.0000033385606,0.00003248067,0.00026840853,0.96124804,0.0000714874,0.035890345,0.00018238842],"about_ca_topic_score_codex":0.000013850941,"about_ca_topic_score_gemma":0.000022825698,"teacher_disagreement_score":0.035786927,"about_ca_system_score_codex":0.000046865298,"about_ca_system_score_gemma":0.00009173554,"threshold_uncertainty_score":0.70252335},"labels":[],"label_agreement":null},{"id":"W186048506","doi":"10.2144/00296bm03","title":"Plasmid-Enhanced Strategy for PCR-Mediated Mutagenesis with Difficult DNA Templates","year":2000,"lang":"en","type":"article","venue":"BioTechniques","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Genetics; Gene; Plasmid; Computational biology; Molecular biology","score_opus":0.009024542452943905,"score_gpt":0.2805563672536825,"score_spread":0.27153182480073856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W186048506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9484795,0.00030385918,0.04968022,0.00007609353,0.000024613211,0.00044407195,0.00006155539,0.00016836009,0.0007617712],"genre_scores_gemma":[0.99263614,0.00038069184,0.0054968065,0.0000674389,0.00012320714,0.0001456715,0.00031984065,0.00003913575,0.0007910522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991524,0.0000116359115,0.00015518365,0.00032156866,0.00007793739,0.0002812666],"domain_scores_gemma":[0.99959314,0.0000114678705,0.000022923416,0.00024218923,0.00006134629,0.000068918926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000671272,0.00019173928,0.00014346113,0.000034194916,0.00006880525,0.000026557693,0.00013745454,0.00022855871,0.00007028774],"category_scores_gemma":[0.000013525811,0.00014138268,0.000057776586,0.00007282277,0.00004741494,0.0000031952632,0.00001840726,0.000053868265,0.000008287979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012568774,0.000032635115,0.000012734956,0.000023812043,0.00003308619,0.0000013135705,0.000021146569,0.00040089467,0.9903468,0.0000068580043,0.0010777218,0.007917349],"study_design_scores_gemma":[0.00032460756,0.0005879344,0.00014711762,0.000017243232,0.000014885478,0.000008257617,0.000022471744,0.00012248865,0.96224946,0.000014271674,0.036243904,0.00024738844],"about_ca_topic_score_codex":0.000014112861,"about_ca_topic_score_gemma":0.000023306615,"teacher_disagreement_score":0.044183414,"about_ca_system_score_codex":0.000008884326,"about_ca_system_score_gemma":0.000025846724,"threshold_uncertainty_score":0.57654184},"labels":[],"label_agreement":null},{"id":"W1870558638","doi":"10.1128/aem.01248-15","title":"Coupling the CRISPR/Cas9 System with Lambda Red Recombineering Enables Simplified Chromosomal Gene Replacement in Escherichia coli","year":2015,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":282,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Waterloo","funders":"","keywords":"Recombineering; CRISPR; Cas9; Biology; Genome editing; Genetics; Plasmid; Homologous recombination; Escherichia coli; Gene; DNA","score_opus":0.005467233457581778,"score_gpt":0.19925630402220776,"score_spread":0.193789070564626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1870558638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964573,0.0008194937,0.00201969,0.000050490526,0.00008721039,0.00031180514,0.000017438395,0.00001533674,0.00022124761],"genre_scores_gemma":[0.9987763,0.00012475182,0.00058148656,0.000078048855,0.00007575607,0.00006974871,0.00020759605,0.000027362928,0.000058941183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990861,0.000016552722,0.00019902819,0.00036810897,0.000039171166,0.0002910576],"domain_scores_gemma":[0.99961555,0.000010413542,0.000049819075,0.0002474405,0.0000034571426,0.00007330839],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016771976,0.00019627999,0.00018203336,0.000023360903,0.00006419155,0.00001412415,0.00011465072,0.00012803549,0.000004606444],"category_scores_gemma":[0.00000289455,0.0001502388,0.000021806643,0.00004156464,0.00010053944,0.000002220613,0.00015028127,0.00010658323,0.000004402086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001567226,0.000029528976,0.0016732122,0.00001831086,0.00003798195,0.0000044519074,0.00008975189,0.00836379,0.98938745,0.000030289288,0.0001298053,0.00007872443],"study_design_scores_gemma":[0.0028843405,0.00056934747,0.0034345658,0.000025716206,0.00003521354,0.0002216019,0.0030015737,0.0015125116,0.9751611,0.000005701394,0.012672969,0.00047539774],"about_ca_topic_score_codex":0.000024821304,"about_ca_topic_score_gemma":0.00002312907,"teacher_disagreement_score":0.0142263705,"about_ca_system_score_codex":0.000054653934,"about_ca_system_score_gemma":0.000015867996,"threshold_uncertainty_score":0.6126561},"labels":[],"label_agreement":null},{"id":"W1889206973","doi":"10.1139/y05-098","title":"Somatic DNA recombination in a mouse genomic region, BC-1, in brain and non-brain tissueThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Homologous recombination; Non-allelic homologous recombination; Genetics; Somatic cell; DNA; genomic DNA; Molecular biology; Chromosome; Recombination; Genetic recombination; Gene","score_opus":0.003664826009444858,"score_gpt":0.2274156351503555,"score_spread":0.22375080914091064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1889206973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99757653,0.00045834025,0.0000072515986,0.0013091357,0.00015878104,0.00014670513,0.0000056089057,5.324756e-7,0.00033713863],"genre_scores_gemma":[0.9988576,0.00015914101,0.00006395424,0.00037888993,0.00020770967,0.0000049542996,0.0000057958982,0.000008951555,0.0003129954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991025,0.00015552182,0.00038759733,0.00014144248,0.000034955527,0.00017800448],"domain_scores_gemma":[0.9995895,0.000051162307,0.00019215173,0.000060132938,0.000047346402,0.00005970002],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003628705,0.00009487519,0.00023450245,0.00024223076,0.000026087819,0.0000052098208,0.000096685464,0.00015596848,0.0016168003],"category_scores_gemma":[0.000031190688,0.000088205925,0.00003324003,0.00014053393,0.000112199814,0.000010953072,0.000016361508,0.0001979419,4.128546e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008695626,0.000054362736,0.0026726534,0.00008174796,0.00001692339,0.0000058876744,0.001194128,0.00039212458,0.9887059,0.0000060162615,0.0066440026,0.00013930017],"study_design_scores_gemma":[0.0023405247,0.0003542907,0.026753161,0.000025173063,0.000020711044,0.000020496833,0.00021395407,0.00031840045,0.9660523,0.0004772054,0.0033104643,0.000113315386],"about_ca_topic_score_codex":0.0023101987,"about_ca_topic_score_gemma":0.016343096,"teacher_disagreement_score":0.024080507,"about_ca_system_score_codex":0.000032524986,"about_ca_system_score_gemma":0.000194885,"threshold_uncertainty_score":0.99929583},"labels":[],"label_agreement":null},{"id":"W1894320934","doi":"10.1128/mbio.00861-15","title":"CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani","year":2015,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Cas9; Genome editing; Guide RNA; Leishmania donovani; Genetics; Gene; Computational biology; Visceral leishmaniasis","score_opus":0.013584815404047835,"score_gpt":0.2830346327586065,"score_spread":0.2694498173545587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1894320934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907961,0.0014683022,0.0036649546,0.00014302063,0.00039526244,0.00011070861,0.000012006946,0.000025517827,0.0033841573],"genre_scores_gemma":[0.9981404,0.000040894927,0.00063525024,0.0001540711,0.00051926315,0.000010211665,0.00011998999,0.000021378031,0.00035856257],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99925584,0.00001589392,0.00016204803,0.0002288105,0.00008860749,0.00024878283],"domain_scores_gemma":[0.99961334,0.000004913085,0.000026407073,0.00020749931,0.000044864144,0.00010297273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017779594,0.00011308544,0.0001047539,0.000047992868,0.000018233795,0.000017908687,0.00012844731,0.00010814761,0.00001664661],"category_scores_gemma":[0.000105901476,0.00012014994,0.00003356147,0.00010057105,0.000020571624,0.0000024396697,0.000085041625,0.00008670536,0.000051610263],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000337909,0.00006247657,0.013509594,0.000023323577,0.000026292897,0.00003276664,0.00029877937,0.0013438953,0.97710294,0.000033185243,0.005891749,0.0016411857],"study_design_scores_gemma":[0.0028293512,0.00045114718,0.043797124,0.000031704607,0.000020238507,0.000065807086,0.0009417535,0.0011771548,0.38172898,0.00011723288,0.5680205,0.0008190028],"about_ca_topic_score_codex":0.00005678648,"about_ca_topic_score_gemma":0.00013534674,"teacher_disagreement_score":0.595374,"about_ca_system_score_codex":0.000020665115,"about_ca_system_score_gemma":0.000037366608,"threshold_uncertainty_score":0.48995724},"labels":[],"label_agreement":null},{"id":"W1894740506","doi":"10.1111/mmi.12644","title":"The three major types of <scp>CRISPR</scp>‐<scp>Cas</scp> systems function independently in <scp>CRISPR RNA</scp> biogenesis in <scp><i>S</i></scp><i>treptococcus thermophilus</i>","year":2014,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; National Institutes of Health; China Scholarship Council","keywords":"Trans-activating crRNA; CRISPR; Biogenesis; Biology; Locus (genetics); RNA; Genetics; Cas9; Gene; Computational biology","score_opus":0.004721626667271593,"score_gpt":0.22554413974898235,"score_spread":0.22082251308171075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1894740506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95148814,0.024530428,0.01833281,0.00005888118,0.0015518089,0.0014882615,0.00019921806,0.000092689595,0.0022577688],"genre_scores_gemma":[0.995633,0.0010484798,0.0002550798,0.00043926842,0.00043657195,0.00032805945,0.00053009955,0.0002241892,0.0011052436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99399066,0.0007644049,0.0014778012,0.0016360505,0.000339812,0.0017912665],"domain_scores_gemma":[0.9959273,0.0011167316,0.0006286521,0.0016991848,0.00034023737,0.0002879058],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0013815992,0.00106143,0.0011817828,0.0005437549,0.00024432014,0.00013350247,0.0013402093,0.0014187538,0.000004185285],"category_scores_gemma":[0.0022333157,0.00095209613,0.0005446529,0.0008928529,0.0004332379,0.000026301695,0.00068937795,0.0007541042,0.00009095349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014405194,0.00020854009,0.008958903,0.00016990642,0.00039232522,0.000047853013,0.00035675435,0.0042360425,0.97813296,0.0002514645,0.0065598404,0.00067099434],"study_design_scores_gemma":[0.0021677741,0.0007216779,0.0070556346,0.00011517527,0.00018722891,0.00016531491,0.001379224,0.0003781788,0.83688533,0.0002394437,0.1505577,0.00014730894],"about_ca_topic_score_codex":0.00044100685,"about_ca_topic_score_gemma":0.0011618155,"teacher_disagreement_score":0.14399786,"about_ca_system_score_codex":0.000120512006,"about_ca_system_score_gemma":0.00018868678,"threshold_uncertainty_score":0.99987763},"labels":[],"label_agreement":null},{"id":"W1903612145","doi":"10.1093/genetics/156.2.809","title":"Mechanisms Involved in Targeted Gene Replacement in Mammalian Cells","year":2000,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Genetics; Gene; Computational biology","score_opus":0.0062355955637299456,"score_gpt":0.24727210698638752,"score_spread":0.24103651142265758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1903612145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994592,0.0013905908,0.0031821616,0.00005637656,0.00012869097,0.0002279351,0.000011777083,0.000010739711,0.00039972112],"genre_scores_gemma":[0.9862906,0.0007336841,0.011817025,0.00019110105,0.00006397671,0.000028256045,0.00007879472,0.00003084788,0.0007657193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988518,0.00003542033,0.00028413793,0.0003594463,0.000116369105,0.00035284893],"domain_scores_gemma":[0.99949586,0.000003532852,0.000024003299,0.00038188914,0.00001689921,0.00007780337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015816525,0.00016815799,0.00013858406,0.00007428705,0.000018848366,0.000013528049,0.00017001097,0.00015280912,0.00020565244],"category_scores_gemma":[0.0000067170886,0.00019223549,0.000045172113,0.00015017329,0.00001863471,0.0000012675703,0.000054257427,0.00009163358,0.00003079683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046942572,0.00005442363,0.0012705883,0.000011204238,0.000007790544,0.000010577667,0.00007437243,0.019712482,0.9749722,0.0000080922,0.0003748121,0.0034565185],"study_design_scores_gemma":[0.0008419326,0.00019120659,0.007586529,0.000009646959,0.0000051380966,0.00000372633,0.00005837163,0.0011868529,0.9736032,0.00012257445,0.016139142,0.00025171004],"about_ca_topic_score_codex":0.000035592562,"about_ca_topic_score_gemma":0.0005931168,"teacher_disagreement_score":0.018525628,"about_ca_system_score_codex":0.00002473606,"about_ca_system_score_gemma":0.000034316843,"threshold_uncertainty_score":0.78391355},"labels":[],"label_agreement":null},{"id":"W1906870688","doi":"10.1186/s13073-015-0215-6","title":"Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing","year":2015,"lang":"en","type":"article","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":270,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Genome editing; Human genetics; Computational biology; DNA; CRISPR; Genome; Biology; Genetics; Medicine; Bioinformatics; Gene","score_opus":0.02076915456627666,"score_gpt":0.31437981954354527,"score_spread":0.2936106649772686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1906870688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892768,0.0037989926,0.0048684236,0.000355033,0.00033018048,0.00018055338,0.000025026764,0.000025285166,0.0011396912],"genre_scores_gemma":[0.9972007,0.00015512054,0.0003361133,0.0002124415,0.0014584996,0.000010645405,0.00046531917,0.000019160521,0.00014200175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898326,0.00003164925,0.00030453262,0.00024408796,0.0001889847,0.00024746402],"domain_scores_gemma":[0.9994211,0.000018647672,0.00008229771,0.00016168872,0.00012501278,0.00019125853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003408541,0.00015246167,0.00022370236,0.000069147,0.000027907472,0.0000032898408,0.000104754516,0.00011390402,0.000109244706],"category_scores_gemma":[0.00022329304,0.00012749332,0.000041605068,0.00013183824,0.00011708818,0.0000024990609,0.00008694948,0.00009330381,0.000013437671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038189555,0.000028399178,0.00032713462,0.000024211557,0.000040686915,0.000013916698,0.00021563696,0.00204823,0.99630064,0.000004571172,0.00070875545,0.00024960813],"study_design_scores_gemma":[0.007123748,0.0031319978,0.015207008,0.00007666642,0.0002367994,0.0001204578,0.0013832347,0.0013643721,0.8771063,0.0001347015,0.09343833,0.00067639723],"about_ca_topic_score_codex":0.0000148956215,"about_ca_topic_score_gemma":0.0000034928134,"teacher_disagreement_score":0.11919437,"about_ca_system_score_codex":0.000020396214,"about_ca_system_score_gemma":0.000037198824,"threshold_uncertainty_score":0.51990265},"labels":[],"label_agreement":null},{"id":"W1922040927","doi":"10.1038/nbt.3404","title":"Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition","year":2015,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":630,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Cas9; CRISPR; Guide RNA; Biology; Genome editing; Computational biology; Genome; DNA; Staphylococcus aureus; Genetics; Gene; Bacteria","score_opus":0.010485145841825505,"score_gpt":0.28570670082254446,"score_spread":0.27522155498071893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1922040927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93243897,0.037778463,0.026693111,0.001678638,0.0005477253,0.00031285518,0.00006515056,0.00009704929,0.00038803025],"genre_scores_gemma":[0.99663967,0.00030296374,0.0024789164,0.0001777298,0.00019676307,0.000017971757,0.00009384278,0.000026469452,0.00006569274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898815,0.000040868465,0.00022430968,0.00032056967,0.0001424102,0.00028366677],"domain_scores_gemma":[0.9993394,0.000018446564,0.00010505963,0.00036345603,0.00011999392,0.000053667973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029367514,0.00016985166,0.00016792132,0.00007777792,0.00006245022,0.000011263121,0.00031401493,0.0010928469,0.00000591902],"category_scores_gemma":[0.00040794048,0.00013675257,0.000075192576,0.00019184848,0.00011440748,0.00000350862,0.00015330075,0.0005884123,0.00000451067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004300263,0.000022095126,0.0003612614,0.000019719202,0.000042618853,0.0000023658502,0.000059088747,0.0001065306,0.972797,0.000043895005,0.017174462,0.009328006],"study_design_scores_gemma":[0.00048545693,0.00016560074,0.00008173243,0.000014651042,0.000022846505,0.00001130414,0.00034704254,0.00021758703,0.9390907,0.00016347994,0.059218317,0.00018128198],"about_ca_topic_score_codex":0.000022580167,"about_ca_topic_score_gemma":0.0000110984265,"teacher_disagreement_score":0.06420068,"about_ca_system_score_codex":0.000015361054,"about_ca_system_score_gemma":0.0000340894,"threshold_uncertainty_score":0.8429036},"labels":[],"label_agreement":null},{"id":"W1933897339","doi":"10.1002/9780470559277.ch140202","title":"SNIPER Peptide‐Mediated Degradation of Endogenous Proteins","year":2015,"lang":"en","type":"article","venue":"Current Protocols in Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research","keywords":"Endogeny; Peptide; Intracellular; Cell biology; Gene knockdown; Autophagy; Chaperone (clinical); Protein degradation; Function (biology); Biology; Computational biology; Chemistry; Biochemistry; Medicine; Gene","score_opus":0.06601285111260946,"score_gpt":0.39249052190248296,"score_spread":0.3264776707898735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1933897339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9720375,0.00094118685,0.0060000033,0.00004479249,0.00016774869,0.01998032,0.0000428678,0.00002593797,0.000759633],"genre_scores_gemma":[0.98171,0.00002407303,0.0013809334,0.000014610101,0.00015000907,0.016357958,0.00033170712,0.000015539128,0.000015178746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902546,0.000057484554,0.00032222626,0.0002824996,0.000074750635,0.00023758972],"domain_scores_gemma":[0.99948984,0.000017823742,0.00007660282,0.00023791725,0.0000872057,0.00009062876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022773408,0.0001371629,0.00019240983,0.000047382193,0.000009552431,0.000003993947,0.00019487503,0.000174006,0.00000867552],"category_scores_gemma":[0.0004648054,0.00012426656,0.00005132661,0.000109861576,0.00009123362,0.0000023545224,0.00010910273,0.00015105572,0.000006686151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008667844,0.00013926755,0.008006636,0.000059550897,0.000007680096,5.110911e-7,0.00002960662,0.000020278634,0.98502696,0.000058057023,0.00015845739,0.006406298],"study_design_scores_gemma":[0.001030343,0.00025752632,0.00012239163,0.000041298965,0.0000031949169,0.000008125278,0.000015949914,0.000064883156,0.9660341,0.0001550869,0.032119054,0.00014801187],"about_ca_topic_score_codex":0.000007863057,"about_ca_topic_score_gemma":0.000003987208,"teacher_disagreement_score":0.031960595,"about_ca_system_score_codex":0.000022310782,"about_ca_system_score_gemma":0.000094746385,"threshold_uncertainty_score":0.5067443},"labels":[],"label_agreement":null},{"id":"W1941336070","doi":"10.1186/s13072-015-0023-7","title":"Strategies for precision modulation of gene expression by epigenome editing: an overview","year":2015,"lang":"en","type":"review","venue":"Epigenetics & Chromatin","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Genome editing; Epigenome; Biology; Effector; CRISPR; Computational biology; Transcription activator-like effector nuclease; Zinc finger nuclease; Cas9; Epigenetics; Genetics; Genomics; Genome; DNA methylation; Gene; Gene expression; Cell biology","score_opus":0.05798794850904982,"score_gpt":0.39477678034780883,"score_spread":0.336788831838759,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1941336070","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008901821,0.9287115,0.06832878,0.0000024013868,0.00032810555,0.0010865146,0.00052691513,0.000022223916,0.00010341588],"genre_scores_gemma":[0.0010448954,0.9688873,0.024106415,0.0000060022003,0.0007938982,0.00019813057,0.00466718,0.0001403302,0.00015584442],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99758583,0.00014346882,0.0009507412,0.0006520902,0.0003097506,0.00035812217],"domain_scores_gemma":[0.9981855,0.000040871346,0.00055030547,0.00082623283,0.00022231397,0.0001747551],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004962906,0.0005163422,0.0010596778,0.000097823126,0.000068306486,0.000051547042,0.000461653,0.000581695,0.000014608504],"category_scores_gemma":[0.000077200966,0.00048288715,0.0003400772,0.00013130013,0.00004990099,0.000009198134,0.00012717934,0.00012331075,0.0000040516625],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018980492,0.00018498756,0.0000034912687,0.0121034095,0.00014529792,9.278154e-7,0.00015973426,0.002157121,0.34775174,0.000042988286,0.006249054,0.63118225],"study_design_scores_gemma":[0.00033409882,0.000620839,0.000007415188,0.0018743458,0.00022320915,0.000006171728,0.00007129065,0.00035506807,0.050512414,0.00014848151,0.9452822,0.00056442263],"about_ca_topic_score_codex":0.0000063782063,"about_ca_topic_score_gemma":0.0000046745536,"teacher_disagreement_score":0.9390332,"about_ca_system_score_codex":0.000040450363,"about_ca_system_score_gemma":0.00030877138,"threshold_uncertainty_score":0.9997623},"labels":[],"label_agreement":null},{"id":"W1946893752","doi":"10.1093/protein/gzv033","title":"An<i>Escherichia coli</i>system for evolving improved light-controlled DNA-binding proteins","year":2015,"lang":"en","type":"article","venue":"Protein Engineering Design and Selection","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Canada; College of Family Physicians of Canada; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNA; Computational biology; DNA-binding protein; Escherichia coli; Protein engineering; Fluorescent protein; Chemistry; Biophysics; Transcription factor; Biology; Cell biology; Biochemistry; Gene; Green fluorescent protein","score_opus":0.008385636232611786,"score_gpt":0.2383533629872648,"score_spread":0.22996772675465302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1946893752","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26933995,0.00039750844,0.72821975,0.000019004201,0.00012506549,0.0017631139,0.0000016734238,0.0001154156,0.000018503291],"genre_scores_gemma":[0.9217762,0.000004493957,0.07650183,0.0000073747997,0.00036573873,0.0011048063,0.000013793095,0.0000562525,0.0001695481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989631,0.00004207677,0.00022799766,0.0003540898,0.00009583302,0.00031688507],"domain_scores_gemma":[0.99948424,0.0000113839515,0.000058804177,0.00013278742,0.00013749569,0.00017528117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054800446,0.00022593794,0.00023073526,0.00008427759,0.00009561468,0.00008528695,0.000090386966,0.00016884679,7.800483e-7],"category_scores_gemma":[0.00015510558,0.00022653582,0.00006237666,0.00012061149,0.0000072752823,0.00001600867,0.000018221557,0.000094316434,9.769178e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032191884,0.000023968782,0.0000121034245,0.0001015952,0.00005051675,4.008879e-7,0.000083199724,0.012673113,0.98633164,0.00003685055,0.00003484755,0.00032985312],"study_design_scores_gemma":[0.0020274941,0.0006875213,0.00001851536,0.00003028438,0.000023320898,0.000009042769,0.000036112837,0.31943452,0.67656934,0.000005395242,0.0009396796,0.00021875958],"about_ca_topic_score_codex":0.00000842775,"about_ca_topic_score_gemma":0.0000027334906,"teacher_disagreement_score":0.6524362,"about_ca_system_score_codex":0.000066063985,"about_ca_system_score_gemma":0.000089914116,"threshold_uncertainty_score":0.9237863},"labels":[],"label_agreement":null},{"id":"W1948902556","doi":"10.1093/genetics/164.4.1419","title":"Identification of <i>Trans</i>-dominant Modifiers of <i>Prat</i> Expression in <i>Drosophila melanogaster</i>","year":2003,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Biology; Drosophila melanogaster; Genetics; Enhancer; Gene; Variegation (histology); Reporter gene; Coding region; Cis-regulatory module; Compound eye; Molecular biology; Gene expression","score_opus":0.007189270823124441,"score_gpt":0.26292614184682483,"score_spread":0.2557368710237004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1948902556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95195645,0.0024920483,0.04486181,0.000014019846,0.00014311072,0.00016014105,0.000020906664,0.0000026337236,0.00034890333],"genre_scores_gemma":[0.99719805,0.00065453636,0.00199769,0.00002124152,0.000024151379,0.000010249827,0.000016839162,0.000017857095,0.000059388913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903,0.00004440434,0.00041831218,0.00021444187,0.00012767753,0.00016519979],"domain_scores_gemma":[0.99942535,0.000008572911,0.000110059395,0.00035488728,0.000058307218,0.000042839674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020211341,0.00011685888,0.00015996232,0.0000564855,0.000014399166,0.000004046052,0.00013553296,0.000113779184,0.0000046208434],"category_scores_gemma":[0.000037307564,0.00012174513,0.00006535181,0.0001128378,0.00005365206,0.0000019565146,0.00002614181,0.000051927927,7.0540193e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002153584,0.000054608452,0.0019715053,0.000054537915,0.0000076279516,6.5547863e-7,0.00011363268,0.00866018,0.9887008,0.000027957298,0.00011757513,0.0002693953],"study_design_scores_gemma":[0.0005178365,0.00009361832,0.001217223,0.000024339755,0.000012178666,0.000005016436,0.00008062966,0.00016427404,0.9940813,0.00007944503,0.0036118857,0.00011221384],"about_ca_topic_score_codex":0.0000020146808,"about_ca_topic_score_gemma":0.000011265807,"teacher_disagreement_score":0.045241617,"about_ca_system_score_codex":0.0000051010147,"about_ca_system_score_gemma":0.000035796405,"threshold_uncertainty_score":0.49646223},"labels":[],"label_agreement":null},{"id":"W1954913131","doi":"10.1186/s13024-015-0031-x","title":"CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases","year":2015,"lang":"en","type":"review","venue":"Molecular Neurodegeneration","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Chinese Academy of Sciences; National Institute of Neurological Disorders and Stroke; National Institute on Aging; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; National Institutes of Health","keywords":"CRISPR; Cas9; Genome editing; Neuroscience; Biology; Computational biology; Animal model; Human genetics; Disease; Bioinformatics; Medicine; Gene; Genetics; Pathology","score_opus":0.01928035696845785,"score_gpt":0.3215779986340965,"score_spread":0.3022976416656386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1954913131","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0034277055,0.6574367,0.33700618,0.0000078685225,0.0003626407,0.0011299445,0.000576762,0.000035953715,0.00001618317],"genre_scores_gemma":[0.0200439,0.96099454,0.012177248,0.00012605585,0.001198932,0.0006187291,0.004140914,0.0005475113,0.00015217773],"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968983,0.00017662389,0.00090216164,0.0010650561,0.0003828714,0.00057497283],"domain_scores_gemma":[0.99819595,0.000038888997,0.00033590963,0.0008625264,0.00037061409,0.00019611107],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025871056,0.0007598598,0.0011509882,0.00024482392,0.000077186734,0.00012395895,0.00045030855,0.00042319065,0.0000037801096],"category_scores_gemma":[0.00034296105,0.0007952953,0.0006802945,0.00028568844,0.000030442498,0.000023562114,0.0002465318,0.0002300075,0.0000026489333],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002007163,0.00056199316,0.000010009402,0.017281147,0.00086922135,0.00010470835,0.000191158,0.46126762,0.3852011,0.0014938929,0.0068371366,0.1259813],"study_design_scores_gemma":[0.0013230867,0.001238295,0.000008797404,0.0009901597,0.0018631526,0.00010923966,0.0000118635935,0.06734245,0.098456144,0.000052394244,0.82660145,0.002002954],"about_ca_topic_score_codex":0.0000041949143,"about_ca_topic_score_gemma":0.000004278788,"teacher_disagreement_score":0.8197643,"about_ca_system_score_codex":0.00004625767,"about_ca_system_score_gemma":0.00035853253,"threshold_uncertainty_score":0.9994498},"labels":[],"label_agreement":null},{"id":"W1955727822","doi":"10.1038/npg.els.0000581","title":"Homologous Genetic Recombination during Bacterial Conjugation","year":2001,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Homologous recombination; Genetic recombination; Homologous chromosome; DNA; Circular bacterial chromosome; Recombination; Genetics; In vitro recombination; Chromosome; Biology; Gene; Base pair; Molecular cloning; Peptide sequence","score_opus":0.006237123280081178,"score_gpt":0.26629854082102733,"score_spread":0.26006141754094614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1955727822","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36891294,0.006055594,0.0021207875,0.000058799837,0.0028419385,0.00041617037,0.000041274925,0.0000627333,0.6194898],"genre_scores_gemma":[0.31235117,0.039801057,0.012098037,0.00007288721,0.006208876,0.00008255884,0.0003265692,0.0004310607,0.6286278],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99903446,0.00003253641,0.00022635896,0.00034198997,0.00017549212,0.00018916583],"domain_scores_gemma":[0.99953735,0.0000077638215,0.00017445142,0.0001933866,0.000025498637,0.00006154271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111904585,0.00016200327,0.00017734797,0.00014502533,0.000047192145,0.00001069827,0.00024823984,0.00020512853,0.0006132639],"category_scores_gemma":[0.00010917708,0.00015974972,0.000056472032,0.00013748542,0.0001566021,0.0000023870368,0.00006450228,0.000052751595,0.000012991186],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011856569,0.00034355404,0.039712295,0.000991315,0.00037107966,0.00002689091,0.00055017386,0.002774133,0.39106214,0.00019570281,0.5246597,0.039194472],"study_design_scores_gemma":[0.0011539714,0.0006725642,0.015634857,0.00017945477,0.000062146915,0.000037615097,0.00018085813,0.000057332596,0.040079966,0.00012774109,0.9408709,0.00094261346],"about_ca_topic_score_codex":0.00010242642,"about_ca_topic_score_gemma":0.00010428792,"teacher_disagreement_score":0.4162112,"about_ca_system_score_codex":0.0000061192336,"about_ca_system_score_gemma":0.00012817438,"threshold_uncertainty_score":0.671481},"labels":[],"label_agreement":null},{"id":"W1961449438","doi":"10.1534/genetics.115.180208","title":"The Transgenic RNAi Project at Harvard Medical School: Resources and Validation","year":2015,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":721,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; Cancer Research UK; NIH Office of the Director; National Key Research and Development Program of China; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China; National Institute of General Medical Sciences; School of Medicine, New York University; Institute of Genetics; National Institutes of Health; Yale University; Cold Spring Harbor Laboratory; York University; Howard Hughes Medical Institute","keywords":"RNA interference; Biology; Genetics; Computational biology; Stock (firearms); Phenotype; Genome; Gene; Engineering; RNA","score_opus":0.016492520597505132,"score_gpt":0.3041229774277539,"score_spread":0.2876304568302488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1961449438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922558,0.0042801015,0.0022272838,0.00034207388,0.00016282588,0.00014750235,0.000005197382,0.0000143879815,0.0005648378],"genre_scores_gemma":[0.9950282,0.0024815649,0.0008426497,0.00013562487,0.00037964483,0.000018531438,0.00003001305,0.000022712817,0.0010610521],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99918914,0.00004407949,0.00014673547,0.00019628335,0.00023330898,0.00019043301],"domain_scores_gemma":[0.999448,0.000013435425,0.00002518362,0.00024717528,0.0000504467,0.00021575451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030750904,0.00010357348,0.000069602145,0.000017342065,0.00010066715,0.00004006039,0.000160919,0.0001222043,0.000013013473],"category_scores_gemma":[0.00020551759,0.00007866789,0.000034527377,0.00005043673,0.00007794137,0.0000011662183,0.00011397547,0.00007038841,0.000015463758],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005208873,0.0001229435,0.04159322,0.00012725845,0.00042331926,0.00001695156,0.0023439252,0.0032870995,0.72461975,0.00011568355,0.15651295,0.070316],"study_design_scores_gemma":[0.0005552732,0.00019632374,0.0024678695,0.0000075127446,0.000022942133,0.000044180862,0.00015018445,0.000469654,0.19538897,0.00004296501,0.8004925,0.00016156783],"about_ca_topic_score_codex":0.000006160659,"about_ca_topic_score_gemma":0.00010186767,"teacher_disagreement_score":0.6439796,"about_ca_system_score_codex":0.000011031408,"about_ca_system_score_gemma":0.00010623436,"threshold_uncertainty_score":0.32079834},"labels":[],"label_agreement":null},{"id":"W1963666953","doi":"10.1016/j.socscimed.2005.07.024","title":"Hyped biomedical science or uncritical reporting? Press coverage of genomics (1992–2001) in Québec","year":2005,"lang":"en","type":"article","venue":"Social Science & Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université Laval; Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Genomics; Context (archaeology); Social media; Bioethics; Press release; Political science; Public relations; Genetics; Biology; Law; Genome; Management","score_opus":0.01835380676193802,"score_gpt":0.36387107168943605,"score_spread":0.345517264927498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963666953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928045,0.00030653185,0.0022296286,0.0014565621,0.00020045946,0.00011917662,0.000003419744,0.000009176662,0.0028705194],"genre_scores_gemma":[0.99863714,0.00007363302,0.00031079096,0.0002511831,0.00059923145,0.00000504814,0.0000037912253,0.0000073168894,0.0001118568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803823,0.000013842156,0.00055795535,0.00037861083,0.0005507186,0.00046062315],"domain_scores_gemma":[0.9993268,0.000020622123,0.00014973806,0.0001981764,0.000115451665,0.00018916851],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0018192945,0.00010598609,0.00021339535,0.00010826441,0.00014023541,0.0000115318735,0.00040764172,0.00007753089,0.00003208667],"category_scores_gemma":[0.0028144037,0.000082575054,0.000032355856,0.00060585485,0.0029862912,0.000010352329,0.00012651845,0.000106049876,8.35813e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032032418,0.000058031346,0.002127452,0.000015039791,0.0000026670648,0.000008242121,0.0011367053,0.000048501293,0.98293847,0.00011559825,0.0005192985,0.012997987],"study_design_scores_gemma":[0.0029859033,0.00120329,0.043163326,0.00013446949,0.00005029558,0.00013862793,0.0014863694,0.0028024788,0.78192824,0.00014037796,0.16527122,0.0006954078],"about_ca_topic_score_codex":0.0013504396,"about_ca_topic_score_gemma":0.0008116545,"teacher_disagreement_score":0.20101021,"about_ca_system_score_codex":0.00011661901,"about_ca_system_score_gemma":0.001227843,"threshold_uncertainty_score":0.999727},"labels":[],"label_agreement":null},{"id":"W1963775677","doi":"10.1038/mt.2014.11","title":"Development of a Web Course on Gene Therapy by the International Consortium of Gene Therapy","year":2014,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences","keywords":"Genetic enhancement; Medicine; Viral vector; Internal medicine; Oncology; Virology; Gene; Biology; Genetics; Recombinant DNA","score_opus":0.012096840026379601,"score_gpt":0.28045697244487555,"score_spread":0.26836013241849593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963775677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91671515,0.02617719,0.017934833,0.03640675,0.0008266994,0.0010366396,0.000181829,0.00003066705,0.00069027505],"genre_scores_gemma":[0.55894923,0.019155681,0.0064614033,0.40699396,0.0023526915,0.00037932929,0.0035381254,0.0004475983,0.0017219748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979732,0.000117765216,0.00053493987,0.0005086204,0.0005415335,0.0003239376],"domain_scores_gemma":[0.9985713,0.000028151042,0.00032165126,0.0008605741,0.00017413414,0.000044185486],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003157022,0.0004557103,0.00041039722,0.00007647879,0.000056938778,0.000024188581,0.00088158005,0.0005130212,0.00007325823],"category_scores_gemma":[0.000010173632,0.00033998393,0.00029682892,0.00008018202,0.00014792114,0.0000016224878,0.00004979242,0.00037554538,0.0000055802248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016478106,0.00011292374,0.000027764227,0.000010065334,0.0008106054,0.000008054174,0.00010403234,0.00010906518,0.89468294,0.0000042018637,0.09047847,0.0134871015],"study_design_scores_gemma":[0.0008753831,0.0001865658,0.00003536951,0.000012126303,0.0000064398846,0.000008088152,0.000006435491,0.000016485106,0.52749884,0.000005359673,0.47115576,0.000193128],"about_ca_topic_score_codex":0.000007709378,"about_ca_topic_score_gemma":0.0000011923369,"teacher_disagreement_score":0.38067728,"about_ca_system_score_codex":0.00001995439,"about_ca_system_score_gemma":0.00020245144,"threshold_uncertainty_score":0.9999052},"labels":[],"label_agreement":null},{"id":"W1963859492","doi":"10.1074/jbc.m901540200","title":"Inhibition of Furin/Proprotein Convertase-catalyzed Surface and Intracellular Processing by Small Molecules","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Furin; Proprotein convertase; Proprotein Convertases; Biochemistry; Biology; Enzyme; Intracellular; Drug discovery; Chemistry; Cell biology","score_opus":0.008990566013320258,"score_gpt":0.24392539463360538,"score_spread":0.2349348286202851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963859492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98453605,0.0076810447,0.0075219544,0.00010753468,0.000012559348,0.000051894185,0.000009497317,0.0000041912394,0.00007525966],"genre_scores_gemma":[0.9968544,0.00043409123,0.0025265033,0.000032583175,0.000082217324,5.555711e-7,0.00003696462,0.000005756795,0.000026891928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992863,0.000015853806,0.00032759283,0.00015325747,0.0000813408,0.00013564978],"domain_scores_gemma":[0.9995069,0.0000075576845,0.00020752157,0.00009154539,0.000097690245,0.000088781824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017285754,0.00012679276,0.00020232108,0.000009540493,0.000022776605,0.000012383713,0.00009135231,0.00019334475,0.000012674619],"category_scores_gemma":[0.000086072265,0.00009810592,0.000072487645,0.000036517333,0.00006539996,0.000003183014,0.000030969484,0.00013528309,1.9177098e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094830335,0.00006701064,0.0002484872,0.000053509717,0.0000146299735,0.000008730757,0.000015162176,0.00007493964,0.996378,9.1226394e-7,0.000069765,0.002974022],"study_design_scores_gemma":[0.00045908394,0.00025063916,0.0003881767,0.000049062644,0.000013372326,0.00009876587,0.000058702273,0.00008059475,0.99803376,0.000060702885,0.000388073,0.000119044525],"about_ca_topic_score_codex":0.0000010019619,"about_ca_topic_score_gemma":1.0931119e-7,"teacher_disagreement_score":0.012318371,"about_ca_system_score_codex":0.000006814187,"about_ca_system_score_gemma":0.00002671956,"threshold_uncertainty_score":0.40006432},"labels":[],"label_agreement":null},{"id":"W1963985319","doi":"10.1371/journal.pone.0114275","title":"TALEN/CRISPR-Mediated eGFP Knock-In Add-On at the OCT4 Locus Does Not Impact Differentiation of Human Embryonic Stem Cells towards Endoderm","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"","keywords":"CRISPR; Transcription activator-like effector nuclease; Biology; Embryonic stem cell; Gene knockin; Cas9; Endoderm; Cell biology; Genome editing; Stem cell; Gene targeting; Genetics; Gene","score_opus":0.01451145985752559,"score_gpt":0.26183441171267247,"score_spread":0.24732295185514688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963985319","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99877656,0.00026308256,0.00025830444,0.00007376962,0.000064532105,0.0002318983,0.00006935412,0.000014020363,0.00024850076],"genre_scores_gemma":[0.99863786,0.00013575776,0.000021942376,0.000042782693,0.00013606556,0.00002228033,0.00010634418,0.000027418726,0.0008695586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989657,0.00006588214,0.00023392634,0.00026728868,0.00021653934,0.00025069388],"domain_scores_gemma":[0.99934363,0.00003424554,0.00009080922,0.00042148738,0.000048859794,0.000060944072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014456807,0.0001796307,0.00022703507,0.000051883442,0.00005046006,0.000013199656,0.00017965105,0.000126263,0.00006703937],"category_scores_gemma":[0.00003202097,0.00011916632,0.00010146183,0.00006603066,0.000041156276,0.0000024786718,0.00009513179,0.00010941746,0.000014497307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005457565,0.00024618796,0.0020682288,0.00007499758,0.00010242047,5.251997e-7,0.00007910025,0.0002877859,0.9961122,0.000005521763,0.00010582781,0.00086261553],"study_design_scores_gemma":[0.0006292006,0.00037101857,0.014180934,0.000053946416,0.000048811406,5.4334515e-7,0.000022282331,0.00067181385,0.98375165,0.000007558246,0.00010846909,0.0001537781],"about_ca_topic_score_codex":0.000041393574,"about_ca_topic_score_gemma":0.00022945362,"teacher_disagreement_score":0.012360569,"about_ca_system_score_codex":0.00003476986,"about_ca_system_score_gemma":0.00001860617,"threshold_uncertainty_score":0.48594615},"labels":[],"label_agreement":null},{"id":"W1964110089","doi":"10.1139/g05-124","title":"Significant positive correlation between the recombination rate and GC content in the human pseudoautosomal region","year":2006,"lang":"en","type":"article","venue":"Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pseudoautosomal region; GC-content; Recombination; Biology; Fixation (population genetics); Gene conversion; Genetics; Mitochondrial DNA; Gene; Genome","score_opus":0.014790261342993804,"score_gpt":0.25410867975701684,"score_spread":0.23931841841402304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964110089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936265,0.00031506017,0.0046082996,0.0005054963,0.000033490178,0.0002141457,0.000004230842,0.0000042110446,0.0006885769],"genre_scores_gemma":[0.9993577,0.00002547012,0.000021234559,0.000075206684,0.00013151548,0.000014007222,0.00013475273,0.000006351121,0.000233743],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995434,0.000064692256,0.00011423748,0.00013189584,0.000046286637,0.00009946348],"domain_scores_gemma":[0.99979657,0.000018347946,0.000034447225,0.00011903958,0.000020873944,0.000010712412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019860464,0.000066379274,0.00005262707,0.000019476834,0.000079750884,0.000022034099,0.000061559665,0.000048257385,9.583043e-7],"category_scores_gemma":[0.000008232141,0.000044747456,0.000021391901,0.00004286299,0.000029453864,0.0000016798086,0.00002159212,0.000060447415,0.0000012926025],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000143410025,0.00003130625,0.024117993,0.000007843572,0.000018282793,0.000005815874,0.00040303817,0.0013179621,0.9716568,0.0012132523,0.00015365751,0.0010597288],"study_design_scores_gemma":[0.00028875182,0.00010119203,0.9865318,0.0000043990344,0.000012523314,0.000008957039,0.00014473412,0.00007591388,0.011263771,0.00034285907,0.0011465519,0.00007855519],"about_ca_topic_score_codex":0.000088424895,"about_ca_topic_score_gemma":0.00003206228,"teacher_disagreement_score":0.9624138,"about_ca_system_score_codex":0.00000890564,"about_ca_system_score_gemma":0.0000054511634,"threshold_uncertainty_score":0.18247482},"labels":[],"label_agreement":null},{"id":"W1964131961","doi":"10.1002/eji.200737654","title":"Activation‐induced cytidine deaminase induces DNA break repair events more frequently in the Ig switch region than other sites in the mammalian genome","year":2007,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Guelph","funders":"","keywords":"Cytidine deaminase; Somatic hypermutation; Biology; Immunoglobulin class switching; Activation-induced (cytidine) deaminase; Gene; Immunoglobulin light chain; Gene conversion; Immunoglobulin heavy chain; Plasmid; Molecular biology; Enhancer; Genetics; Cytidine; Genome; Antibody; DNA; Gene rearrangement; Gene expression; B cell; Enzyme","score_opus":0.017253117840388316,"score_gpt":0.2780029390210663,"score_spread":0.260749821180678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964131961","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965898,0.00089694135,0.0008219606,0.000903906,0.00010037097,0.00011954723,0.000001090057,0.0000043179316,0.00056208577],"genre_scores_gemma":[0.99897444,0.00010608822,0.00014445324,0.00041799157,0.000266356,0.0000014618043,0.000008947377,0.000023897353,0.00005635173],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985855,0.00043806914,0.00043840954,0.00015620279,0.00012842132,0.00025338246],"domain_scores_gemma":[0.99933624,0.000044354732,0.00020758194,0.0003284983,0.000057727535,0.000025622008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001722007,0.00014638445,0.00014085899,0.00014673769,0.000050314837,0.000013760751,0.00050884223,0.000067639725,0.0000051113316],"category_scores_gemma":[0.00012975902,0.000094903306,0.000102394384,0.00018664976,0.000044270688,0.000009352867,0.00005592982,0.0003372463,0.000003856189],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015649987,0.000094534094,0.004492471,0.000005656524,0.000053366537,0.00023605702,0.0016688243,0.00009158257,0.9915159,0.00001840755,0.00008136139,0.0015853365],"study_design_scores_gemma":[0.0012300797,0.00082080986,0.8117321,0.000052328058,0.000018823413,0.0010884542,0.0035460556,0.0000039811416,0.17453426,0.000031702726,0.0067508775,0.00019049716],"about_ca_topic_score_codex":0.000025517098,"about_ca_topic_score_gemma":0.000054683194,"teacher_disagreement_score":0.8169817,"about_ca_system_score_codex":0.000024772198,"about_ca_system_score_gemma":0.000027937818,"threshold_uncertainty_score":0.38700444},"labels":[],"label_agreement":null},{"id":"W1966445473","doi":"10.1038/mtna.2012.55","title":"Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Zinc finger nuclease; Integrase; Myogenesis; Genetic enhancement; Biology; Insertional mutagenesis; Transplantation; Gene targeting; Molecular biology; Cell biology; Gene; Cancer research; Myocyte; Genome editing; Genetics; CRISPR; Genome; Medicine","score_opus":0.003712537081160202,"score_gpt":0.23236892091297723,"score_spread":0.22865638383181702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966445473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96760976,0.0007897348,0.031088274,0.000040676023,0.000056816727,0.0002857669,0.000025573541,0.000015450127,0.00008795405],"genre_scores_gemma":[0.9967685,0.00022577363,0.0022812858,0.00010657221,0.00005795157,0.000041763367,0.0004454645,0.00004205593,0.000030669733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902827,0.00005185457,0.00027814845,0.00028787006,0.00012258261,0.00023130166],"domain_scores_gemma":[0.999584,0.0000035799414,0.000064585394,0.00023559462,0.000057880137,0.000054339573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007548301,0.00018184767,0.00015893127,0.0000841217,0.00003528297,0.000014147983,0.00016303179,0.00014704921,0.0001427777],"category_scores_gemma":[0.0000046779555,0.00019414755,0.00010891461,0.0001198964,0.000051487063,0.0000075889207,0.000019907238,0.000089388006,0.000013560731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021879538,0.000071544266,0.00015179723,0.000021157832,0.000035239384,0.0000067718447,0.00011187913,0.0006382317,0.9934427,0.000008203769,0.00005299955,0.0054375846],"study_design_scores_gemma":[0.0010569944,0.0002722744,0.03096676,0.000014160712,0.000008830838,0.0000126115965,0.000027804206,0.00019595344,0.9664128,0.000060879047,0.00076671835,0.0002042389],"about_ca_topic_score_codex":0.0001246366,"about_ca_topic_score_gemma":0.000020237283,"teacher_disagreement_score":0.030814964,"about_ca_system_score_codex":0.000013230703,"about_ca_system_score_gemma":0.000013276362,"threshold_uncertainty_score":0.79171073},"labels":[],"label_agreement":null},{"id":"W1966985073","doi":"10.2196/jmir.2313","title":"Utilizing Social Media to Study Information-Seeking and Ethical Issues in Gene Therapy","year":2013,"lang":"en","type":"article","venue":"Journal of Medical Internet Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NeuroDevNet; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Canadian Institutes of Health Research; Genome British Columbia","keywords":"Social media; Internet privacy; Psychology; Social psychology; Information seeking; Computer science; World Wide Web","score_opus":0.049731486065011536,"score_gpt":0.45662315220101396,"score_spread":0.4068916661360024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966985073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99287087,0.0007837451,0.0011862483,0.0048546586,0.00009981305,0.00013277745,3.4592665e-7,0.0000015990453,0.000069968366],"genre_scores_gemma":[0.9983596,0.00058068876,0.00030497284,0.00027881438,0.00044394436,0.000009097964,0.0000014172693,0.000006278667,0.000015185978],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99822044,0.00017895931,0.0003618872,0.00009037246,0.0009317498,0.00021656639],"domain_scores_gemma":[0.99933296,0.00010871467,0.000035716996,0.00007382543,0.00024481615,0.00020397214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029974733,0.00006793464,0.0001447656,0.00018313632,0.00002723708,0.00007646605,0.00030859205,0.0002144263,0.00017391267],"category_scores_gemma":[0.0014943319,0.00005234006,0.000031992073,0.00011735374,0.00006316215,0.0000078106295,0.0002189383,0.0008247739,0.00000868119],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065415085,0.0006203378,0.038870905,0.00007992391,0.00035675775,0.00017568974,0.05971779,0.000043812834,0.19616872,0.00030209505,0.05460533,0.6484045],"study_design_scores_gemma":[0.012413164,0.0074992594,0.55712306,0.0005491008,0.000021239279,0.0005600605,0.053105693,0.0048419316,0.25772554,0.0010854541,0.10413935,0.00093615573],"about_ca_topic_score_codex":0.00011674395,"about_ca_topic_score_gemma":0.000058698683,"teacher_disagreement_score":0.6474683,"about_ca_system_score_codex":0.000014724543,"about_ca_system_score_gemma":0.000066736335,"threshold_uncertainty_score":0.3583278},"labels":[],"label_agreement":null},{"id":"W1967197994","doi":"10.1007/s00253-014-5616-8","title":"Evolutionary engineering by genome shuffling","year":2014,"lang":"en","type":"review","venue":"Applied Microbiology and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Genome; Biology; Genetic diversity; Genetics; Mutagenesis; Organism; Computational biology; Shuffling; DNA shuffling; Genetic Fitness; Genetic recombination; Recombination; Evolutionary biology; Directed evolution; Mutation; Gene; Mutant; Computer science","score_opus":0.004314839882952576,"score_gpt":0.24307215123368067,"score_spread":0.23875731135072809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967197994","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018286721,0.9906129,0.008335113,0.00003316923,0.00017419322,0.0003657111,0.00011871628,0.00009332001,0.00008397453],"genre_scores_gemma":[0.0007975195,0.9953552,0.001467446,0.00007134308,0.00020731673,0.00009328884,0.0017699765,0.00007058325,0.00016736257],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982631,0.00002563035,0.00040968295,0.0007958367,0.00002276791,0.0004829489],"domain_scores_gemma":[0.9992996,0.000029475827,0.00013160415,0.00046148343,0.000013546293,0.00006428156],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000136605,0.0005067117,0.00096360553,0.00018067674,0.00008296965,0.000009854178,0.0003553952,0.0023415063,0.000010108377],"category_scores_gemma":[0.000023773644,0.00047175202,0.00016389016,0.0001303838,0.00021451779,9.108807e-7,0.0003854252,0.00050076994,0.000037288526],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008897919,0.000028072465,7.117729e-7,0.002365693,0.00034365218,0.0000029113933,0.0000037154844,0.000016230084,0.78289866,0.00090513524,0.0022213338,0.21120499],"study_design_scores_gemma":[0.00016145862,0.00009281373,3.7377043e-7,0.00015162454,0.00014274735,0.0003753293,0.000003148372,0.0000035958824,0.0075302846,0.000008506651,0.99103415,0.00049594935],"about_ca_topic_score_codex":0.0000013420118,"about_ca_topic_score_gemma":0.000001185301,"teacher_disagreement_score":0.98881286,"about_ca_system_score_codex":0.0000199744,"about_ca_system_score_gemma":0.00004413565,"threshold_uncertainty_score":0.99977344},"labels":[],"label_agreement":null},{"id":"W1967517562","doi":"10.1038/nbt787","title":"Site-specific cassette exchange and germline transmission with mouse ES cells expressing φC31 integrase","year":2003,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute on Drug Abuse","keywords":"Integrase; Recombinase; Integrases; Site-specific recombination; FLP-FRT recombination; Biology; Homologous recombination; Cre recombinase; Genetics; Schizosaccharomyces pombe; Cre-Lox recombination; Genome; DNA; Computational biology; Saccharomyces cerevisiae; Recombination; Gene; Genetic recombination; Transgene","score_opus":0.0038635183852094644,"score_gpt":0.241207306388595,"score_spread":0.23734378800338554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967517562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93696827,0.024901634,0.037194274,0.00040827278,0.00011285802,0.00016761309,0.000017981876,0.00007479827,0.0001543206],"genre_scores_gemma":[0.9823644,0.0029923916,0.01394906,0.00013980581,0.00007124503,0.00001035097,0.000038700222,0.00003691418,0.00039711111],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990555,0.0000252246,0.00012653631,0.00044262828,0.00007956744,0.00027054176],"domain_scores_gemma":[0.9994959,0.00001022728,0.000038537313,0.00034911613,0.000033674303,0.000072496594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008749408,0.000212777,0.00016181091,0.00010455671,0.00006878882,0.000019006984,0.000113402275,0.0010383199,0.000020064566],"category_scores_gemma":[0.000020473397,0.0001710995,0.000037531896,0.000116431904,0.000115042276,0.0000026920325,0.00004090789,0.00049592287,0.000002195303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041609776,0.000026365386,0.000048396905,0.000028561664,0.000017099053,0.000018371311,0.000031329517,0.000029331886,0.98929566,0.00016450856,0.0011905173,0.009108267],"study_design_scores_gemma":[0.0003763558,0.0001431684,0.000022505488,0.000016037686,0.00001012291,0.00006570733,0.000035236862,0.000023954426,0.69699407,0.000010123652,0.30214164,0.00016108988],"about_ca_topic_score_codex":0.0000025765517,"about_ca_topic_score_gemma":0.00001612791,"teacher_disagreement_score":0.30095112,"about_ca_system_score_codex":0.000008529187,"about_ca_system_score_gemma":0.000016312553,"threshold_uncertainty_score":0.80084735},"labels":[],"label_agreement":null},{"id":"W1967860434","doi":"10.1186/1471-2156-8-23","title":"X chromosome transmission ratio distortion in Cftr +/- intercross-derived mice","year":2007,"lang":"en","type":"article","venue":"BMC Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada)","funders":"","keywords":"Chromosome; Distortion (music); Transmission (telecommunications); Genetics; Biology; Computer science; Gene; Telecommunications","score_opus":0.010535092002933153,"score_gpt":0.3002694113260518,"score_spread":0.2897343193231186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967860434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6455032,0.0019301063,0.35210967,0.0000118622,0.00014122728,0.000112943715,0.0000027366348,0.000010307208,0.00017791898],"genre_scores_gemma":[0.99124867,0.0002722155,0.0078561995,0.000054461576,0.00020564084,0.00000754347,0.00006863492,0.00002722765,0.0002594123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990196,0.00001994253,0.0002860697,0.0002858436,0.000109069384,0.00027945777],"domain_scores_gemma":[0.99958664,0.000010246142,0.00003781886,0.00023522193,0.000037253856,0.0000928085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019686311,0.00015123542,0.00011291618,0.000058799487,0.00003730535,0.000017772758,0.00013789587,0.00015671842,0.00001801651],"category_scores_gemma":[0.000024469578,0.0001613246,0.000067254536,0.00010095183,0.000038048613,0.0000022701008,0.000043633885,0.00008405674,0.00000804432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057702542,0.00004335834,0.007358111,0.000030626816,0.000005928153,0.0000031100635,0.0001556286,0.00260959,0.9811515,0.0000043857144,0.00006631565,0.008513732],"study_design_scores_gemma":[0.0005885147,0.00015317327,0.08676088,0.00001888504,0.0000086066675,0.000010961694,0.000075104675,0.0007333403,0.89971167,0.000014995302,0.011712308,0.00021155938],"about_ca_topic_score_codex":0.000011989886,"about_ca_topic_score_gemma":0.00035768838,"teacher_disagreement_score":0.3457454,"about_ca_system_score_codex":0.000026469574,"about_ca_system_score_gemma":0.000040188945,"threshold_uncertainty_score":0.6578626},"labels":[],"label_agreement":null},{"id":"W1968478090","doi":"10.1038/nbt1204supp-dc42","title":"South Korean biotechnology—a rising industrial and scientific powerhouse","year":2004,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; University of Toronto","funders":"","keywords":"Biotechnology; Business; Natural resource economics; International trade; Biology; Economics","score_opus":0.0065558051915561855,"score_gpt":0.2594968428745111,"score_spread":0.2529410376829549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968478090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802016,0.01207023,0.0033897783,0.002868745,0.000982469,0.00019489157,0.000019224935,0.00022410837,0.000048929447],"genre_scores_gemma":[0.9956993,0.0003037957,0.0034527564,0.00012481361,0.0002107027,0.0000063594725,0.000035027948,0.000034295776,0.00013298455],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856275,0.000013998226,0.00020131769,0.0007024029,0.00011269767,0.00040684207],"domain_scores_gemma":[0.99914896,0.0000069208527,0.000069141344,0.0006492122,0.000050956416,0.000074796364],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00020883803,0.00023396678,0.0002086416,0.00032506997,0.00015867087,0.00004232261,0.0003191803,0.0030270598,0.0000032827577],"category_scores_gemma":[0.00039386572,0.00022376911,0.00006237519,0.00039274263,0.0006254263,0.0000041867074,0.0003037392,0.00090677664,0.000009462119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003028084,0.000025542582,0.00017508643,0.000011106369,0.00005734462,0.000015627003,0.000058395097,0.00007308493,0.98559976,0.004843838,0.00044226082,0.008667657],"study_design_scores_gemma":[0.00095751375,0.00022393791,0.00006822568,0.000024600611,0.000020892276,0.00015017246,0.00018718923,0.000008090704,0.94613814,0.0008446512,0.05111617,0.0002604204],"about_ca_topic_score_codex":0.0000046473706,"about_ca_topic_score_gemma":0.000026571553,"teacher_disagreement_score":0.05067391,"about_ca_system_score_codex":0.000029348243,"about_ca_system_score_gemma":0.000080418875,"threshold_uncertainty_score":0.99826723},"labels":[],"label_agreement":null},{"id":"W1970515032","doi":"10.1128/jb.01184-12","title":"The CRISPR/Cas Adaptive Immune System of Pseudomonas aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages","year":2012,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":302,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"CRISPR; Biology; Bacteriophage; Lytic cycle; Trans-activating crRNA; Pseudomonas aeruginosa; Cas9; Computational biology; Microbiology; Genetics; Gene; Bacteria; Virus; Escherichia coli","score_opus":0.005809962767705519,"score_gpt":0.25882599026794456,"score_spread":0.25301602750023905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970515032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9683833,0.026961083,0.0037260635,0.0001250617,0.00065691385,0.00008022348,0.000008610098,0.000003639311,0.000055106317],"genre_scores_gemma":[0.99719334,0.0004601804,0.0019564203,0.00002463167,0.00031609624,0.0000033579533,0.0000019732252,0.00001201197,0.000031972988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912673,0.000063841326,0.00039236413,0.00009551078,0.00008145893,0.00024011018],"domain_scores_gemma":[0.99930024,0.00008408318,0.00020999686,0.00015828745,0.00013987033,0.00010752485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043819434,0.00012626401,0.000257071,0.000053222877,0.000050325783,0.000009696356,0.00018120826,0.000099406534,0.0000015059588],"category_scores_gemma":[0.00016405845,0.000088268265,0.00008063103,0.000051787214,0.000058385554,0.0000075439043,0.000083093204,0.00013180503,7.249324e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024646515,0.000011383471,0.0018141017,0.00004263532,0.000119158474,0.0000039315564,0.0002613945,0.00010557436,0.99639726,0.0001775119,0.00016035073,0.0006602512],"study_design_scores_gemma":[0.0006265893,0.0005149803,0.14410047,0.00012419536,0.00006095555,0.00039933604,0.00086506346,0.000028740402,0.84174097,0.000008694217,0.011327228,0.0002027554],"about_ca_topic_score_codex":0.0000032031735,"about_ca_topic_score_gemma":0.000006961602,"teacher_disagreement_score":0.15465625,"about_ca_system_score_codex":0.000016728673,"about_ca_system_score_gemma":0.00002642616,"threshold_uncertainty_score":0.35994753},"labels":[],"label_agreement":null},{"id":"W1970617888","doi":"10.1371/journal.pone.0109213","title":"Protospacer Adjacent Motif (PAM)-Distal Sequences Engage CRISPR Cas9 DNA Target Cleavage","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Genome editing; Nuclease; Biology; Computational biology; Palindrome; Guide RNA; Chromatin; DNA; In silico; Genetics; RNA; Subgenomic mRNA; Gene","score_opus":0.018045254863638678,"score_gpt":0.25543315177735126,"score_spread":0.2373878969137126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970617888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9821886,0.0006319135,0.010952147,0.0002729455,0.000095134164,0.0006157351,0.000029514125,0.00006108119,0.0051529505],"genre_scores_gemma":[0.99250066,0.00009455905,0.005485704,0.0001417136,0.00044372331,0.00010290421,0.00007954164,0.000040292944,0.0011108707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881583,0.000056564557,0.00018489962,0.00037652816,0.00022427343,0.00034189396],"domain_scores_gemma":[0.9993474,0.0000132544355,0.000048567184,0.00039735806,0.000056622623,0.00013680334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021457596,0.00019732784,0.00019490304,0.000032222306,0.000090050824,0.000033831886,0.00018270621,0.00013175825,0.00006649799],"category_scores_gemma":[0.00014728158,0.00019228602,0.000073152616,0.00006200837,0.000056634493,0.0000041012927,0.00010399761,0.00015844098,0.000044137465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002439265,0.00026279138,0.0018878254,0.00011388233,0.0001003905,0.0000038314993,0.00010229143,0.000107758315,0.9959208,0.000046076893,0.0009786383,0.00045135233],"study_design_scores_gemma":[0.00033835875,0.00028491192,0.0017330892,0.000042017014,0.000038350478,0.000004016928,0.00006867853,0.0004942836,0.98711926,0.000038488823,0.009576056,0.0002624754],"about_ca_topic_score_codex":0.000018435481,"about_ca_topic_score_gemma":0.000030777304,"teacher_disagreement_score":0.010312111,"about_ca_system_score_codex":0.000014923984,"about_ca_system_score_gemma":0.000027835144,"threshold_uncertainty_score":0.7841196},"labels":[],"label_agreement":null},{"id":"W1970785285","doi":"10.4161/cc.6.8.4105","title":"BRCA1 Haploinsufficiency, but not Heterozygosity for a BRCA1-truncating Mutation, Deregulates Homologous Recombination","year":2007,"lang":"en","type":"article","venue":"Cell Cycle","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Haploinsufficiency; Biology; Loss of heterozygosity; Homologous recombination; Genetics; Allele; DNA repair; Genome instability; Wild type; Mutation; Homologous chromosome; Cancer research; Phenotype; Mutant; Molecular biology; DNA damage; DNA; Gene","score_opus":0.006980131369100921,"score_gpt":0.2717742563932637,"score_spread":0.2647941250241628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970785285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82491535,0.00034872285,0.17374259,0.00003770755,0.00018952202,0.00020129303,0.000008053491,0.000028846835,0.00052789383],"genre_scores_gemma":[0.99403304,0.000017101293,0.005204096,0.00008697823,0.00013116699,0.00001725508,0.00010818448,0.00002496019,0.00037722287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909866,0.0000123699465,0.00021591135,0.00030142596,0.000084309344,0.0002873091],"domain_scores_gemma":[0.999529,0.000035651967,0.00006886626,0.00019885351,0.00010080629,0.00006680222],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030189546,0.00012776913,0.00010148612,0.000046000845,0.00013877866,0.000024758154,0.00012857208,0.00012255699,0.00000670958],"category_scores_gemma":[0.00008281729,0.00014071011,0.000078323545,0.000070190785,0.00003438569,0.000004154372,0.00004514266,0.000054138978,0.000007159105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003235921,0.00009142686,0.0005972085,0.00004449491,0.0000112505995,0.0000024592778,0.00013856364,0.0027577318,0.98707306,0.000029536339,0.00018688943,0.009034987],"study_design_scores_gemma":[0.000568852,0.00021538862,0.017996818,0.0000060433827,0.000013697726,0.000020845775,0.000116159485,0.0027475294,0.9770925,0.00016754659,0.0008661071,0.00018850068],"about_ca_topic_score_codex":0.000031273397,"about_ca_topic_score_gemma":0.00005445707,"teacher_disagreement_score":0.16911766,"about_ca_system_score_codex":0.000021492502,"about_ca_system_score_gemma":0.000021653965,"threshold_uncertainty_score":0.57379913},"labels":[],"label_agreement":null},{"id":"W1971529589","doi":"10.1038/ncomms5076","title":"Adaptive synonymous mutations in an experimentally evolved Pseudomonas fluorescens population","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Pseudomonas fluorescens; Adaptive evolution; Biology; Genetics; Population; Mutation; Experimental evolution; Evolutionary biology; Computational biology; Gene; Bacteria; Medicine","score_opus":0.0121652172525231,"score_gpt":0.33409441261682543,"score_spread":0.3219291953643023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971529589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864756,0.003376393,0.0070321434,0.00038983044,0.00014687957,0.00033177377,0.000020973068,0.000048883438,0.002177533],"genre_scores_gemma":[0.9796269,0.00006752435,0.01913433,0.00012015669,0.00006391498,0.000053664742,0.00087594567,0.000019129478,0.000038440612],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993418,0.00010008714,0.00015969195,0.0001882149,0.00007802845,0.00013219575],"domain_scores_gemma":[0.99882704,0.000026476237,0.000038257367,0.0009863157,0.00006646666,0.00005541945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011409411,0.000104150415,0.00008617193,0.000067005414,0.00011054349,0.000018681116,0.000407943,0.00020500088,0.000005008729],"category_scores_gemma":[0.00007493768,0.00011511192,0.00004012791,0.00011937864,0.00004380285,0.000007384612,0.00012459751,0.00025389073,0.0000040828977],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006238978,0.0005322893,0.044261403,0.000009803978,0.000049561466,9.2772103e-7,0.00086743635,0.007093357,0.92997026,0.008747324,0.0007820814,0.0076231784],"study_design_scores_gemma":[0.0022707672,0.00075212267,0.76623106,0.00007338577,0.000069608,0.000030342146,0.001746166,0.077823706,0.12964176,0.00087679207,0.019332765,0.001151519],"about_ca_topic_score_codex":0.000049922295,"about_ca_topic_score_gemma":0.0018966753,"teacher_disagreement_score":0.8003285,"about_ca_system_score_codex":0.00002550618,"about_ca_system_score_gemma":0.000017860859,"threshold_uncertainty_score":0.46941277},"labels":[],"label_agreement":null},{"id":"W1972802993","doi":"10.1155/2010/947816","title":"Correction of Fanconi Anemia Group C Hematopoietic Stem Cells Following Intrafemoral Gene Transfer","year":2010,"lang":"en","type":"article","venue":"Anemia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Algorithm; Medicine; Computer science","score_opus":0.004550646414460168,"score_gpt":0.24071438002540718,"score_spread":0.236163733610947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972802993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865301,0.00025370298,0.010592589,0.000012802497,0.0019445171,0.00011907661,0.0000059519,0.00002137178,0.00051985803],"genre_scores_gemma":[0.99860156,0.00004019197,0.0006298759,0.000039125516,0.00022171937,0.000009080764,0.00003243285,0.000027514772,0.00039852675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918705,0.000013923296,0.00021879625,0.0002558727,0.00010678934,0.00021753911],"domain_scores_gemma":[0.9995672,0.000011569802,0.000025100182,0.0002913918,0.00002923799,0.000075480784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111561676,0.00015116764,0.00016352475,0.00003469069,0.000040132698,0.000011914026,0.00013502676,0.00020338368,0.00002915664],"category_scores_gemma":[0.000006298853,0.00015586714,0.00013734333,0.000078375924,0.000035947276,0.0000036357342,0.000027873984,0.00017139548,0.0000070403134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001738769,0.000024051282,0.00075739465,0.000039962073,0.000016455142,0.0000052031405,0.000110887864,0.00025454533,0.9942824,0.000014331151,0.0005875098,0.0038898743],"study_design_scores_gemma":[0.00036732337,0.000121856065,0.00075409014,0.000012863825,0.00003220127,0.00002608537,0.00008239976,0.000179515,0.9955676,0.0000062156005,0.0026708574,0.00017899173],"about_ca_topic_score_codex":0.00002374404,"about_ca_topic_score_gemma":0.00006553977,"teacher_disagreement_score":0.012071402,"about_ca_system_score_codex":0.000005821788,"about_ca_system_score_gemma":0.000027072001,"threshold_uncertainty_score":0.6356078},"labels":[],"label_agreement":null},{"id":"W1973679647","doi":"10.1016/j.molcel.2014.02.028","title":"Largen: A Molecular Regulator of Mammalian Cell Size Control","year":2014,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University Health Network; Jewish General Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Agence Nationale pour la Gestion des Déchets Radioactifs","keywords":"Biology; Cell biology; Mitochondrion; Translation (biology); Cell; Gene; Regulator; Transgene; Messenger RNA; Cell growth; Molecular biology; Genetics","score_opus":0.001669692121390535,"score_gpt":0.21151912193456113,"score_spread":0.2098494298131706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973679647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7714959,0.0017597608,0.21814756,0.00008954492,0.0001463725,0.00024399752,0.000018324681,0.000021409023,0.0080771595],"genre_scores_gemma":[0.99371654,0.00001907212,0.004747746,0.00042699737,0.00007930495,0.000018594854,0.00003115482,0.000065523476,0.0008950515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857557,0.00009099977,0.00030482133,0.00043005173,0.0002182279,0.00038033572],"domain_scores_gemma":[0.9989155,0.000015049418,0.00008664169,0.0007235251,0.00009965072,0.00015966683],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021614041,0.00025741747,0.00026598325,0.000045189117,0.00003306517,0.000015977925,0.00029077454,0.0002025481,0.00004838452],"category_scores_gemma":[0.00007761157,0.00027661875,0.00024117748,0.00010505176,0.00005521757,0.0000019851789,0.00008821171,0.00010079074,0.000020529202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003368375,0.00007533534,0.00023791233,0.0000889704,0.00002812502,0.000013325673,0.000018428838,0.0041594715,0.9944983,0.00015667835,0.00036224537,0.0003275392],"study_design_scores_gemma":[0.001416462,0.00027976758,0.00030402504,0.000008481139,0.000054497013,0.000005218671,0.00001538046,0.0007065151,0.97133875,0.0000770315,0.025492106,0.00030179336],"about_ca_topic_score_codex":0.000011987839,"about_ca_topic_score_gemma":0.0000032194666,"teacher_disagreement_score":0.22222069,"about_ca_system_score_codex":0.000008073676,"about_ca_system_score_gemma":0.00004652541,"threshold_uncertainty_score":0.9999686},"labels":[],"label_agreement":null},{"id":"W1973776098","doi":"10.1371/journal.pgen.1004933","title":"hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Universidad de Buenos Aires; Genome Institute of Singapore; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; RWTH Aachen University; University of Washington","keywords":"Biology; Gene silencing; Chromatin; Endogenous retrovirus; Gene knockdown; Embryonic stem cell; RNA interference; Repressor; Genetics; Molecular biology; Cell biology; Transcription factor; Gene; RNA; Genome","score_opus":0.01741670453844386,"score_gpt":0.259362698291663,"score_spread":0.24194599375321912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973776098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98700994,0.009465318,0.002541083,0.00008790331,0.000220754,0.00016550395,0.000047378468,0.000019033592,0.00044309217],"genre_scores_gemma":[0.99771935,0.00029968238,0.00059453933,0.000099040895,0.00014028509,0.00002071159,0.000062433995,0.000036275487,0.0010276642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989407,0.000034543536,0.00021021969,0.00031395015,0.00018684287,0.00031372477],"domain_scores_gemma":[0.99949145,0.000009043565,0.000032804794,0.00024622862,0.000069857495,0.0001506138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012560941,0.00017914498,0.00015014035,0.000048308622,0.000026225289,0.000022993936,0.0001908021,0.00014716614,0.000011143959],"category_scores_gemma":[0.00000893642,0.00019592128,0.000054763826,0.00010197485,0.000034709457,0.0000026314885,0.00005467694,0.000109168366,0.00001991154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020755666,0.00006967367,0.0010091179,0.000026575392,0.000024594528,0.0000028458878,0.00014919884,0.007268105,0.98703516,0.0000095974065,0.0038809949,0.0005034033],"study_design_scores_gemma":[0.00064731465,0.00020987766,0.00009921963,0.000017497647,0.000017725863,0.0000063681464,0.00026612703,0.0049218787,0.97933394,0.000033104403,0.014195471,0.00025149973],"about_ca_topic_score_codex":0.0000041107437,"about_ca_topic_score_gemma":0.000021685733,"teacher_disagreement_score":0.010709434,"about_ca_system_score_codex":0.00003112191,"about_ca_system_score_gemma":0.00007884682,"threshold_uncertainty_score":0.7989438},"labels":[],"label_agreement":null},{"id":"W1975643185","doi":"10.1038/nature13804","title":"Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":464,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Embryonic stem cell; Biology; Induced pluripotent stem cell; Stem cell; Cell biology; Retrovirus; Transcription factor; Endogenous retrovirus; Genetics; Cell culture; Gene; Genome","score_opus":0.009989408700281237,"score_gpt":0.2435276358812255,"score_spread":0.23353822718094427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975643185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96218634,0.014409833,0.017958999,0.00013472732,0.0016533317,0.00029038286,0.000049797447,0.00008165807,0.0032349208],"genre_scores_gemma":[0.9969137,0.0006116735,0.0011311426,0.00033230096,0.0004216989,0.000009466657,0.00006996419,0.00003290567,0.000477184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991321,0.000029840885,0.00013993964,0.00032235414,0.00013698549,0.00023879205],"domain_scores_gemma":[0.9995067,0.0000076166225,0.00003517495,0.0003243361,0.000057114732,0.00006903302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008763205,0.00017010543,0.00013384575,0.000037878723,0.00006398361,0.00002545301,0.00017841674,0.0007869143,0.000015634625],"category_scores_gemma":[0.000005045691,0.00016193558,0.00010129886,0.000071537055,0.000024921525,0.0000027744798,0.000030388215,0.00046445988,0.000024611083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003222322,0.0000194561,0.00016534614,0.00002924421,0.000017393615,0.0000020747063,0.000049582668,0.0005292756,0.9902313,0.00012778756,0.0040568197,0.0047395127],"study_design_scores_gemma":[0.00027725968,0.00010919589,0.00030874897,0.000008116252,0.000010706985,0.000013916632,0.000018288703,0.00008737205,0.67641807,0.000010841393,0.32258344,0.00015403231],"about_ca_topic_score_codex":0.0000022924419,"about_ca_topic_score_gemma":0.0000071398536,"teacher_disagreement_score":0.3185266,"about_ca_system_score_codex":0.00001358853,"about_ca_system_score_gemma":0.000013663217,"threshold_uncertainty_score":0.66035414},"labels":[],"label_agreement":null},{"id":"W1976428492","doi":"10.1002/humu.10097","title":"Comparison of DNA- and RNA-Based Methods for Detection of TruncatingBRCA1 Mutations","year":2002,"lang":"en","type":"article","venue":"Human Mutation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute; American Cancer Society","keywords":"Biology; Frameshift mutation; Exon; Genetics; DNA sequencing; Single-strand conformation polymorphism; Gene; Molecular biology; Mutation; DNA; Nonsense mutation; COLD-PCR; Point mutation; Missense mutation","score_opus":0.03816431850654028,"score_gpt":0.4204313789619663,"score_spread":0.382267060455426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976428492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56204015,0.00021551651,0.4375651,0.000005372332,0.000023107365,0.000086567736,0.000002985694,0.0000032769542,0.00005791684],"genre_scores_gemma":[0.9730953,0.000002576856,0.026767246,0.000004737575,0.00002623483,0.000019630468,0.000050246577,0.000007808664,0.000026209093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999623,0.000023512472,0.00017312636,0.00009486461,0.000033232085,0.000052264713],"domain_scores_gemma":[0.9997229,0.00002795496,0.000089141395,0.000076277705,0.00006802198,0.000015685087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009992679,0.000049389775,0.00008492636,0.00004306024,0.000040078754,0.0000036264641,0.000025236219,0.000044669905,0.0000062006134],"category_scores_gemma":[0.00006914635,0.000054826865,0.00003331352,0.000039692008,0.000029452782,0.000001638496,0.0000052428245,0.000017905862,1.3005113e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062835416,0.000026324591,0.00017414802,0.000060151226,0.000010077955,1.4376311e-8,0.00025268833,0.0019545488,0.95579314,0.000038344042,0.000010073849,0.041674178],"study_design_scores_gemma":[0.00036915264,0.00027199707,0.00333543,0.000007031028,0.00002508593,6.397513e-7,0.00011617578,0.042605422,0.9529359,0.00011187249,0.00017006489,0.000051273768],"about_ca_topic_score_codex":0.0000044479975,"about_ca_topic_score_gemma":0.00001081324,"teacher_disagreement_score":0.41105515,"about_ca_system_score_codex":0.000003503027,"about_ca_system_score_gemma":0.0000037327661,"threshold_uncertainty_score":0.22357747},"labels":[],"label_agreement":null},{"id":"W1976587150","doi":"10.1016/s0140-6736(03)13674-4","title":"SARS genome patent: symptom or disease?","year":2003,"lang":"en","type":"article","venue":"The Lancet","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Public health; Genome; Business; Public domain; Political science; Medicine; Genetics; Biology; Gene; History","score_opus":0.02585684034758568,"score_gpt":0.2892103592426657,"score_spread":0.26335351889508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976587150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98687637,0.003872888,0.0043980437,0.0005438977,0.00019841401,0.00014181298,0.000035214845,0.00002420208,0.003909151],"genre_scores_gemma":[0.99715304,0.0004914147,0.00022774302,0.0004393835,0.0003642138,0.000011348981,0.000025493666,0.0000127546655,0.001274617],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995553,0.000023207524,0.00006431661,0.00012434338,0.00005244445,0.00018037012],"domain_scores_gemma":[0.99954706,0.000004773981,0.000013436132,0.00037644102,0.000011336476,0.000046965662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008845397,0.000074136224,0.00008442737,0.0000068875893,0.000041693645,0.000013650775,0.00015523112,0.000027297898,0.000048071484],"category_scores_gemma":[0.000042825184,0.000046363257,0.00003551978,0.00003813212,0.000022615595,6.211861e-7,0.000029669036,0.000040140305,0.000022727478],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033612,0.000065629145,0.011036549,0.000082387895,0.00014916396,0.00002136975,0.00016816381,0.002984211,0.9589257,0.0017362025,0.022888659,0.0016057916],"study_design_scores_gemma":[0.0008103717,0.00007728714,0.035614174,0.000010397357,0.00003053852,0.000017537623,0.00003478633,0.00006470668,0.0924387,0.00024319274,0.87041867,0.00023963503],"about_ca_topic_score_codex":0.0000015964848,"about_ca_topic_score_gemma":0.000003887778,"teacher_disagreement_score":0.8664871,"about_ca_system_score_codex":0.0000034935779,"about_ca_system_score_gemma":0.000020058304,"threshold_uncertainty_score":0.18906388},"labels":[],"label_agreement":null},{"id":"W1976673761","doi":"10.1007/s003350010238","title":"Transgenic mice for the preparation of puromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selection","year":2001,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"National Institute of Mental Health","keywords":"Embryonic stem cell; Biology; Puromycin; Transgene; Cell biology; Selection (genetic algorithm); Embryo; Genetically modified mouse; Fibroblast; Stem cell; Genetics; Cell culture; Gene; Protein biosynthesis","score_opus":0.009229808227061901,"score_gpt":0.26091085332448943,"score_spread":0.25168104509742756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976673761","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85054547,0.0023925393,0.14515698,0.00021372877,0.00016367921,0.0011755909,0.00007595023,0.000018226487,0.000257841],"genre_scores_gemma":[0.99163955,0.0001426976,0.001181754,0.000055907287,0.0002658391,0.00018266785,0.00012864688,0.00004245423,0.0063604675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904054,0.000022024433,0.0002332915,0.00031295727,0.00009328852,0.000297899],"domain_scores_gemma":[0.9994835,0.000032065163,0.00009130371,0.00025168655,0.00009052976,0.000050879218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019056443,0.00017062732,0.0001555894,0.00004101248,0.00012262334,0.00002416182,0.00018409628,0.00011913844,0.000011291821],"category_scores_gemma":[0.000005196081,0.00015130485,0.00019286128,0.00010695038,0.00002857256,0.0000049463083,0.00002140904,0.000051118324,0.0000023433186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052266713,0.00003103824,0.0000328543,0.00019255985,0.000064414744,1.1408199e-7,0.00010488053,0.01203905,0.98571557,0.000015106825,0.00056944176,0.00071231544],"study_design_scores_gemma":[0.0015229882,0.0013202323,0.004203744,0.000017940274,0.00014277165,0.00001334077,0.00023495227,0.0017464953,0.8188105,0.00001590394,0.17162248,0.00034859558],"about_ca_topic_score_codex":0.0000087365515,"about_ca_topic_score_gemma":0.00008397119,"teacher_disagreement_score":0.17105304,"about_ca_system_score_codex":0.00003724756,"about_ca_system_score_gemma":0.00008621341,"threshold_uncertainty_score":0.6170033},"labels":[],"label_agreement":null},{"id":"W1977035092","doi":"10.1007/s00335-012-9430-2","title":"Beyond knockouts: cre resources for conditional mutagenesis","year":2012,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; National Institute of Dental and Craniofacial Research; National Human Genome Research Institute; National Institutes of Health","keywords":"Biology; Toolbox; Resource (disambiguation); Sophistication; Set (abstract data type); Function (biology); Computational biology; Mutagenesis; Strain (injury); Data science; Computer science; Genetics; Gene; Mutation","score_opus":0.008082656865509392,"score_gpt":0.2726617455055557,"score_spread":0.2645790886400463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977035092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9613779,0.004402092,0.029815765,0.00015665355,0.00027336163,0.00028708766,0.00034933785,0.000027386306,0.003310381],"genre_scores_gemma":[0.9890589,0.000019572077,0.0026468567,0.00025965448,0.001358503,0.00007101243,0.0003795539,0.000033259308,0.0061726696],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99922395,0.000013246627,0.00013909306,0.00019632943,0.00008189395,0.0003455101],"domain_scores_gemma":[0.9995719,0.000008999535,0.000032068274,0.00021510075,0.000037924343,0.00013401527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013172015,0.00013351081,0.00010139857,0.000038479742,0.00008744843,0.000018582785,0.00012804168,0.0001011416,0.00018558126],"category_scores_gemma":[0.000023633958,0.00013879381,0.00009872403,0.000044508677,0.00003486344,0.00000326041,0.000052897976,0.00003337236,0.000028517083],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056084333,0.00005948566,0.0036294297,0.000065652195,0.0000863759,0.0000013149206,0.00028401974,0.00062397297,0.986804,0.00040651657,0.0068677,0.0011154541],"study_design_scores_gemma":[0.0003927984,0.00011430697,0.0214709,0.0000020743933,0.000029687271,0.000022300848,0.00013993117,0.000019442903,0.13547164,0.00010390789,0.8419699,0.00026311574],"about_ca_topic_score_codex":0.000002663289,"about_ca_topic_score_gemma":0.0000033909284,"teacher_disagreement_score":0.85133237,"about_ca_system_score_codex":0.000010736138,"about_ca_system_score_gemma":0.0000128633355,"threshold_uncertainty_score":0.5659847},"labels":[],"label_agreement":null},{"id":"W1977416347","doi":"10.1038/nmeth.1199","title":"BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals","year":2008,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":628,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Human Genome Research Institute; Wellcome Trust","keywords":"Recombineering; Transgene; Biology; Computational biology; Bacterial artificial chromosome; Gene; Genome; Function (biology); Transfection; Molecular biology; Cell biology; Genetics","score_opus":0.022569180098073634,"score_gpt":0.3982031726603523,"score_spread":0.3756339925622787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977416347","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09042253,0.0021244304,0.9066114,0.00009683042,0.00021000356,0.0004521997,0.000012388701,0.000008872178,0.00006136905],"genre_scores_gemma":[0.32564545,0.00008426188,0.67375386,0.000047915797,0.00015731517,0.00010474929,0.000050958195,0.000017754219,0.00013775557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911445,0.00015608453,0.00023505787,0.00026949766,0.00007425305,0.00015062495],"domain_scores_gemma":[0.9995813,0.000038360686,0.000057146775,0.00021464168,0.00007944816,0.000029140183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007074137,0.00012233361,0.00019075001,0.00007201196,0.000028133809,0.0000032026837,0.00008564324,0.00038279523,0.0000054538687],"category_scores_gemma":[0.00016977903,0.00012034788,0.000093191615,0.00013470165,0.00002070122,0.0000064750734,0.000016611979,0.00015301468,2.6932577e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019690895,0.000028111785,0.000029011246,0.00005446594,0.00002495648,4.7317653e-7,0.00010312739,0.002065214,0.9663626,0.00046077278,0.00008176775,0.030592615],"study_design_scores_gemma":[0.00069566106,0.0002609814,0.0006199382,0.000012902774,0.000016353588,0.0000053677677,0.00003469216,0.00074350764,0.98151684,0.0017035916,0.014258001,0.00013217388],"about_ca_topic_score_codex":0.000012711216,"about_ca_topic_score_gemma":0.000021303535,"teacher_disagreement_score":0.23522292,"about_ca_system_score_codex":0.000010548738,"about_ca_system_score_gemma":0.000038940434,"threshold_uncertainty_score":0.49076444},"labels":[],"label_agreement":null},{"id":"W1978094899","doi":"10.1038/nature09523","title":"The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2344,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Plasmid; Biology; Extrachromosomal DNA; Bacteriophage; Trans-activating crRNA; Microbiology; Genetics; DNA; Cas9; Gene; Escherichia coli","score_opus":0.0016517821835583064,"score_gpt":0.24286169531036536,"score_spread":0.24120991312680706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978094899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944667,0.0026561809,0.00010926681,0.00021680708,0.0017889763,0.00010714054,0.000019452833,0.000021590735,0.0006138471],"genre_scores_gemma":[0.9984333,0.00012817392,0.00023871174,0.00005279278,0.0007669828,0.000008417546,0.000034648332,0.000019929612,0.00031706388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939513,0.000015926167,0.0001196191,0.0002041306,0.00007710156,0.00018808633],"domain_scores_gemma":[0.99954593,0.000016215992,0.00003319791,0.00030972785,0.000035977788,0.000058949878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012837765,0.00012839648,0.000094644885,0.000014083837,0.00014154293,0.000073991345,0.00016549713,0.00072289933,0.000009465882],"category_scores_gemma":[0.000058674406,0.000092080394,0.000050270686,0.000032410568,0.00005517174,0.000002432665,0.00009686651,0.00068902504,0.000004704467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004709294,0.000004599555,0.00010062351,0.00002205701,0.000021037551,0.0000027528622,0.00002763342,0.0000011930657,0.99720305,0.00025529752,0.0007345336,0.001580133],"study_design_scores_gemma":[0.00029061225,0.00004864704,0.017280616,0.000008469256,0.000010968418,0.00006759135,0.000069888425,0.000034623394,0.8197603,0.000004789542,0.1622995,0.00012393908],"about_ca_topic_score_codex":0.000003337832,"about_ca_topic_score_gemma":0.000041110798,"teacher_disagreement_score":0.1774427,"about_ca_system_score_codex":0.000003960205,"about_ca_system_score_gemma":0.000017764123,"threshold_uncertainty_score":0.55756617},"labels":[],"label_agreement":null},{"id":"W1978521084","doi":"10.1016/j.tplants.2007.02.002","title":"Genetic use restriction technologies (GURTs): strategies to impede transgene movement","year":2007,"lang":"en","type":"review","venue":"Trends in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Ministry of Agriculture and Forestry; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transgene; Biology; Biotechnology; Risk analysis (engineering); Genetically modified crops; Genetics; Business; Gene","score_opus":0.04808933475618101,"score_gpt":0.3875349070540248,"score_spread":0.33944557229784383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978521084","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0039059143,0.98586136,0.008797265,0.0000123392265,0.00040866475,0.00032957093,0.00020370304,0.0000735318,0.00040765587],"genre_scores_gemma":[0.003461933,0.99266857,0.0034384264,0.000015719426,0.000071145056,0.000059640013,0.00010042167,0.000023596416,0.00016056579],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979655,0.000018637793,0.00044166672,0.000733971,0.0002935069,0.0005466856],"domain_scores_gemma":[0.999224,0.000019551288,0.00008045478,0.00055908813,0.000027491647,0.00008940957],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000322655,0.00033753048,0.00042938272,0.0009853231,0.0000775797,0.000111578694,0.00065459986,0.0002641894,0.0000048678307],"category_scores_gemma":[0.00004365031,0.0002918335,0.00011771839,0.0013889458,0.00014945626,0.000010019192,0.00016644003,0.00019512563,0.0000053323215],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073311553,0.000025754243,0.000023818484,0.00027831088,0.00001444342,0.000023832703,0.000024612104,0.00089997204,0.0069027543,0.00006654778,0.00023475305,0.9914979],"study_design_scores_gemma":[0.0001429982,0.00028668865,0.00092994736,0.00091661175,0.0000695058,0.000062840416,0.00013653646,0.00005671457,0.005131816,0.000019175543,0.99157387,0.0006732725],"about_ca_topic_score_codex":0.000051024454,"about_ca_topic_score_gemma":0.0002184409,"teacher_disagreement_score":0.99133915,"about_ca_system_score_codex":0.00007472799,"about_ca_system_score_gemma":0.00019725868,"threshold_uncertainty_score":0.9999534},"labels":[],"label_agreement":null},{"id":"W1978734059","doi":"10.1007/s00244-003-3075-9","title":"Atrazine Induces Homologous Recombination But Not Point Mutation in the Transgenic Plant-Based Biomonitoring Assay","year":2004,"lang":"en","type":"article","venue":"Archives of Environmental Contamination and Toxicology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"University of Lethbridge","keywords":"Genotoxicity; Atrazine; Biomonitoring; Ecotoxicology; Pesticide; Biology; Homologous recombination; Toxicology; Chemistry; Genetics; Environmental chemistry; Toxicity; DNA; Ecology","score_opus":0.006955152709926619,"score_gpt":0.24898588946890526,"score_spread":0.24203073675897865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978734059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899646,0.00016178243,0.009186206,0.00030245932,0.0000609884,0.00016764044,0.000021492942,0.000003250086,0.00013158022],"genre_scores_gemma":[0.9991396,0.00012976679,0.00044263748,0.000090355556,0.000022223012,0.000021097467,0.00013406674,0.000006292945,0.000013944067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994513,0.0000750947,0.00015499518,0.00015446736,0.00006154054,0.00010261854],"domain_scores_gemma":[0.9997891,0.000059921167,0.000048276368,0.000080959704,0.000001923361,0.00001977527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014092778,0.00008173167,0.000080381804,0.000075417105,0.000037558457,0.0000049655173,0.000073069496,0.00006397572,0.0000044293547],"category_scores_gemma":[0.000018856035,0.00007351152,0.000031436917,0.000027020482,0.00010025204,0.0000048863635,0.000015980611,0.00006307598,5.808758e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006272169,0.00012862336,0.0011098265,0.000010647879,0.000010445624,0.0000039554916,0.0004630659,0.00060113706,0.9806466,0.00016073433,5.135479e-7,0.016801726],"study_design_scores_gemma":[0.0012066038,0.0006615776,0.31078875,0.000007871763,0.000009562362,0.000022358096,0.00040654567,0.00017617346,0.68643713,0.00015882688,0.000048523747,0.000076080745],"about_ca_topic_score_codex":0.000012056864,"about_ca_topic_score_gemma":0.000068867754,"teacher_disagreement_score":0.3096789,"about_ca_system_score_codex":0.000012212745,"about_ca_system_score_gemma":0.000010731986,"threshold_uncertainty_score":0.29977125},"labels":[],"label_agreement":null},{"id":"W1979308615","doi":"10.1038/sj.onc.1204890","title":"A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element","year":2001,"lang":"en","type":"article","venue":"Oncogene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Cancer Care Ontario; U.S. Department of Defense","keywords":"CREB; Biology; Promoter; Transcriptional regulation; Molecular biology; Transcription factor; Response element; Binding site; Cancer research; Gene expression; Cell biology; Gene; Genetics","score_opus":0.010566535583489321,"score_gpt":0.29738487451348855,"score_spread":0.28681833892999925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979308615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98571986,0.00077374623,0.004383041,0.0005417995,0.00007082228,0.0003278699,0.00001546557,0.0000069762964,0.008160448],"genre_scores_gemma":[0.9980612,0.00012944461,0.00058012764,0.00048839964,0.00018737398,0.000057272395,0.00007421043,0.000008959309,0.00041304002],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999302,0.000029939483,0.00012958673,0.00020761935,0.00012614734,0.00020468843],"domain_scores_gemma":[0.99974245,0.0000049768732,0.000018799059,0.0001667447,0.000027014974,0.00004000444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001568085,0.00010885308,0.000076964265,0.000026469628,0.00003915744,0.000017796065,0.000117085925,0.0000645961,0.00006825848],"category_scores_gemma":[0.000017271284,0.000084682266,0.000055083106,0.00007886106,0.000042395142,0.000002395643,0.000022933222,0.00007073438,0.000021981969],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008175116,0.000115169445,0.0015624275,0.000007969948,0.000026282587,0.000038545917,0.00039925895,0.00025066631,0.9948671,0.00031260104,0.00023972508,0.0020984907],"study_design_scores_gemma":[0.0017387016,0.0005882069,0.00910931,0.000029109622,0.000032021147,0.00036702896,0.00026774197,0.00022545633,0.4392869,0.0001258377,0.547903,0.0003266953],"about_ca_topic_score_codex":0.000018995674,"about_ca_topic_score_gemma":0.00014347232,"teacher_disagreement_score":0.5555802,"about_ca_system_score_codex":0.000013693134,"about_ca_system_score_gemma":0.00006977226,"threshold_uncertainty_score":0.34532425},"labels":[],"label_agreement":null},{"id":"W1979826378","doi":"10.1038/nmeth.2889","title":"Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon","year":2014,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":425,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Transposable element; Biology; Caenorhabditis elegans; Sleeping Beauty transposon system; Genetics; Genome; Transgene; Transposase; Insertion; Caenorhabditis; Gene; Mutation","score_opus":0.008783888759668653,"score_gpt":0.3617103949761183,"score_spread":0.3529265062164496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979826378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.51601195,0.0028710011,0.48072758,0.00004204942,0.00012371376,0.0001015792,0.000004881553,0.000008851963,0.0001083778],"genre_scores_gemma":[0.8729238,0.00012595563,0.12661697,0.00010965574,0.00012983265,0.0000090964895,0.000035459187,0.000021608881,0.000027609876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990215,0.00022599392,0.00017752894,0.00029584466,0.000075084085,0.0002040738],"domain_scores_gemma":[0.99967146,0.000034429107,0.000025634065,0.00017600742,0.000029237808,0.00006322261],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005713494,0.0001525263,0.00019842251,0.000073606076,0.000038065187,0.000013060517,0.00007902491,0.00041224534,0.000004634495],"category_scores_gemma":[0.00010921018,0.00014991168,0.000060963986,0.00013223609,0.000025796982,0.0000034980412,0.000011473662,0.0002642694,1.2178452e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013870824,0.00001544431,0.0002137391,0.0000315875,0.000017097127,0.0000011524452,0.0001213589,0.0044823973,0.9728514,0.000031493313,0.000010450654,0.022085167],"study_design_scores_gemma":[0.002306859,0.00010679058,0.0049342173,0.000022043883,0.00003301381,0.000017920947,0.000025536574,0.028529303,0.9596703,0.000119644035,0.0039926404,0.00024170252],"about_ca_topic_score_codex":0.00004152753,"about_ca_topic_score_gemma":0.00009150193,"teacher_disagreement_score":0.35691187,"about_ca_system_score_codex":0.00000827165,"about_ca_system_score_gemma":0.000017240362,"threshold_uncertainty_score":0.61132205},"labels":[],"label_agreement":null},{"id":"W1980580499","doi":"10.4161/fly.6985","title":"Biolistics for high-throughput transformation and RNA interference in<i>Drosophila melanogaster</i>","year":2008,"lang":"en","type":"article","venue":"Fly","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RNA interference; Biology; Drosophila melanogaster; Transformation (genetics); Gene; Genetics; Transgene; RNA silencing; RNA; Nucleic acid; Cell biology","score_opus":0.013995992820626826,"score_gpt":0.27301799073405364,"score_spread":0.25902199791342684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980580499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87108225,0.00037791464,0.12774707,0.00010676141,0.00012005494,0.00013141046,0.000028940303,0.0000070484,0.00039855682],"genre_scores_gemma":[0.9974896,0.00035529956,0.0017986845,0.00007730304,0.00010294696,0.000015449881,0.000069501555,0.000008377858,0.00008287015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961656,0.000005202633,0.0001125683,0.00012523684,0.000027951628,0.00011250599],"domain_scores_gemma":[0.9998436,0.0000062848085,0.000014467332,0.000087994726,0.000019911333,0.000027766326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037064412,0.00007297501,0.0000726641,0.000021789492,0.00002931996,0.000006016996,0.000049590242,0.00006084247,0.0000019032805],"category_scores_gemma":[0.000015013567,0.00007235468,0.000018334562,0.00002771162,0.000026931793,0.0000028442123,0.000016584414,0.000032155738,0.0000014291677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012257743,0.000044783726,0.0012769579,0.000110404304,0.000024572597,0.0000039757724,0.0009661332,0.00055794884,0.9878479,0.0012233639,0.0009934369,0.0068279444],"study_design_scores_gemma":[0.0024103418,0.00079740724,0.018687567,0.000054161083,0.000021581827,0.000081882696,0.00013669251,0.0018261845,0.95345646,0.0008398745,0.021238925,0.00044893706],"about_ca_topic_score_codex":0.000010392594,"about_ca_topic_score_gemma":0.000024052426,"teacher_disagreement_score":0.12640733,"about_ca_system_score_codex":0.0000042249762,"about_ca_system_score_gemma":0.000011650692,"threshold_uncertainty_score":0.2950538},"labels":[],"label_agreement":null},{"id":"W1980641226","doi":"10.1093/nar/gku1285","title":"CRISPR RNA binding and DNA target recognition by purified Cascade complexes from Escherichia coli","year":2014,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Trans-activating crRNA; CRISPR; Biology; Cas9; RNA; Escherichia coli; DNA; Plasmid; Genetics; Computational biology; Gene","score_opus":0.02737764407464393,"score_gpt":0.33138014935430987,"score_spread":0.30400250527966594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980641226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99089485,0.0007823808,0.005798877,0.00021456124,0.000088253626,0.00018129603,0.000100673526,0.000023587569,0.0019155358],"genre_scores_gemma":[0.99517685,0.0002840228,0.003268137,0.000085347885,0.0003078244,0.000025976551,0.00038593437,0.000040504136,0.00042542344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853146,0.0001586622,0.00017340954,0.0004282186,0.00027693048,0.00043131164],"domain_scores_gemma":[0.9993491,0.00006233931,0.000027501777,0.0002867372,0.000100132056,0.0001741855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053638197,0.00014884648,0.00015603732,0.000074192576,0.00020058124,0.00008705394,0.00020289581,0.00019982125,0.000108761335],"category_scores_gemma":[0.00023184675,0.00015234448,0.00004179864,0.0001382626,0.00013982588,0.000005193439,0.00018739421,0.0002795367,0.000050356364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004268021,0.000025596699,0.00042974664,0.000019100253,0.00002901323,0.000001215955,0.00008233194,0.000005859265,0.98257375,0.000011446818,0.009917186,0.0068620993],"study_design_scores_gemma":[0.0005070658,0.0002094947,0.002252279,0.000019152088,0.0000074240324,0.0000021044104,0.00018330466,0.0008175765,0.9262893,0.0002811881,0.06922899,0.00020212088],"about_ca_topic_score_codex":0.00014708367,"about_ca_topic_score_gemma":0.000022060154,"teacher_disagreement_score":0.059311807,"about_ca_system_score_codex":0.000017865546,"about_ca_system_score_gemma":0.000024417463,"threshold_uncertainty_score":0.62124276},"labels":[],"label_agreement":null},{"id":"W1981092097","doi":"10.1517/17460441.2.7.987","title":"Drug discovery using the regulation of gene expression","year":2007,"lang":"en","type":"article","venue":"Expert Opinion on Drug Discovery","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Drug discovery; Computational biology; Regulation of gene expression; Gene expression; Biology; Epigenetics; Transcriptional regulation; Gene; Disease; Bioinformatics; Genetics; Medicine","score_opus":0.012651796297633754,"score_gpt":0.31544636453534636,"score_spread":0.3027945682377126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981092097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88598543,0.004015303,0.1081792,0.00013167036,0.0010601506,0.0001973013,0.000015584032,0.000012684385,0.00040267096],"genre_scores_gemma":[0.99659675,0.00054185605,0.0010908048,0.00014002896,0.0007821881,0.0000065211534,0.000098195196,0.000029358946,0.0007143043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892265,0.000041548607,0.00028087242,0.00029967385,0.00023316137,0.00022210734],"domain_scores_gemma":[0.9992917,0.00003672337,0.000105442785,0.0004878263,0.00003350633,0.00004475887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028250797,0.00017141349,0.00013289027,0.000054549248,0.00009791977,0.00003989336,0.00019089856,0.000075400014,0.000008176786],"category_scores_gemma":[0.000035025456,0.00012599546,0.00012583684,0.00009061465,0.00006484915,0.00002417226,0.00009166817,0.00007799397,0.0000014164674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012856415,0.000054476383,0.00034721784,0.000009073147,0.000013424918,3.0713846e-7,0.00026882574,0.006627987,0.989281,0.00009885422,0.0025928135,0.0005774517],"study_design_scores_gemma":[0.00028805019,0.00003847696,0.003102864,0.0000709341,0.000002081209,0.0000043228506,0.0005031564,0.00029324804,0.98420274,0.000024378758,0.011299988,0.00016977914],"about_ca_topic_score_codex":0.000038176222,"about_ca_topic_score_gemma":0.0000072103453,"teacher_disagreement_score":0.110611305,"about_ca_system_score_codex":0.000022586542,"about_ca_system_score_gemma":0.000035403005,"threshold_uncertainty_score":0.5137946},"labels":[],"label_agreement":null},{"id":"W1981400366","doi":"10.1093/nar/gku797","title":"The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity","year":2014,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Biological and Environmental Research; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Government of Canada; Genome Canada; Ontario Genomics; National Institute of General Medical Sciences; Ontario Genomics Institute; U.S. Department of Energy","keywords":"Nuclease; Biology; Sulfolobus solfataricus; Cleave; CRISPR; DNA; RecBCD; Helicase; Biochemistry; Micrococcal nuclease; Genetics; DNA repair; Gene; Archaea; Histone; RNA","score_opus":0.012642141557631615,"score_gpt":0.3165874397956631,"score_spread":0.3039452982380315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981400366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99544585,0.00041893765,0.0020728502,0.00076380884,0.00008798077,0.0005915847,0.00013883656,0.000025268859,0.00045488653],"genre_scores_gemma":[0.998551,0.00008303521,0.00017227542,0.00006539945,0.0002836774,0.000054836273,0.000049787395,0.000052565945,0.0006874191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99770266,0.00043681473,0.00019661555,0.00053816737,0.0004581427,0.00066757743],"domain_scores_gemma":[0.9988037,0.00011699349,0.000049810933,0.0005707961,0.00020440186,0.0002543505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073390186,0.00022466271,0.0002147004,0.000048786187,0.0005351236,0.00019881046,0.00038798977,0.00031900592,0.00003574224],"category_scores_gemma":[0.0008930717,0.00017630338,0.00008397119,0.00015979908,0.0003051357,0.000008762681,0.00048924476,0.0005444451,0.000008159651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023350945,0.000055966502,0.0015933053,0.000023081653,0.000099371144,0.0000063709576,0.00013208318,0.000033896962,0.98166,0.00009000867,0.003039868,0.01303251],"study_design_scores_gemma":[0.0040615387,0.0013129486,0.106835246,0.00009277573,0.00005714797,0.000026360825,0.00066310924,0.01261443,0.72490966,0.0014027166,0.14704704,0.0009770232],"about_ca_topic_score_codex":0.0008125602,"about_ca_topic_score_gemma":0.0013477997,"teacher_disagreement_score":0.25675038,"about_ca_system_score_codex":0.000057203117,"about_ca_system_score_gemma":0.00006288238,"threshold_uncertainty_score":0.7189444},"labels":[],"label_agreement":null},{"id":"W1981762151","doi":"10.1242/dev.01286","title":"Interaction with eIF5B is essential for Vasa function during development","year":2004,"lang":"en","type":"article","venue":"Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research","keywords":"Biology; Function (biology); Cell biology","score_opus":0.005634198353892158,"score_gpt":0.2578910894202602,"score_spread":0.252256891066368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981762151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7464697,0.00006139869,0.25296047,0.000038389215,0.00018700633,0.00016494498,9.51155e-7,0.00001640849,0.00010075953],"genre_scores_gemma":[0.96939796,0.000011546409,0.029698037,0.00007776878,0.00012773485,0.000110043235,0.00010082937,0.000021316031,0.00045476796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927986,0.0000027790336,0.00016342662,0.00025911749,0.00010240138,0.00019244071],"domain_scores_gemma":[0.9997436,0.0000018050833,0.000036481033,0.00011071194,0.000056423996,0.000050990257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055230277,0.00013179252,0.00007611532,0.00004269954,0.00011976902,0.000020369303,0.00005767011,0.000058932477,0.000015157528],"category_scores_gemma":[0.00000485455,0.00012324842,0.000027261767,0.0000458555,0.000009209749,0.0000040025407,0.000038000537,0.000039447365,0.000012394326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007431845,0.0001812366,0.002332888,0.00021343127,0.0004695802,0.0000049966357,0.00222247,0.0086942045,0.9511183,0.000048297457,0.0004906997,0.033480696],"study_design_scores_gemma":[0.0009143025,0.00007384524,0.024756478,0.000030930547,0.00000978538,0.000013250515,0.0000930586,0.000006916079,0.88693476,0.0000059483546,0.08696971,0.00019100444],"about_ca_topic_score_codex":0.0000024502524,"about_ca_topic_score_gemma":0.000040351857,"teacher_disagreement_score":0.22326244,"about_ca_system_score_codex":0.00006341875,"about_ca_system_score_gemma":0.00014335915,"threshold_uncertainty_score":0.5025925},"labels":[],"label_agreement":null},{"id":"W1982000482","doi":"10.1080/1521654031000119425","title":"Diversity and Evolution of Mitochondrial RNA Editing Systems","year":2003,"lang":"en","type":"review","venue":"IUBMB Life","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"RNA editing; Biology; RNA; Genetics; Transfer RNA; Sequence (biology); Intron; Computational biology; Gene","score_opus":0.019006767807557823,"score_gpt":0.2969977974398287,"score_spread":0.27799102963227085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982000482","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00055282674,0.9929216,0.0048290524,9.631922e-7,0.0011727025,0.00023408917,0.000035666035,0.000006066476,0.00024706777],"genre_scores_gemma":[0.004458246,0.9939867,0.000137386,0.0000036302472,0.0011647391,0.000011245824,0.00003982878,0.000020420403,0.00017778181],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99919575,0.00005321901,0.0002570125,0.0002471029,0.00010263831,0.00014424924],"domain_scores_gemma":[0.9995136,0.0000122044,0.0001465837,0.00020586191,0.00004129225,0.00008040792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009532011,0.00017590297,0.00047018318,0.000047036316,0.0001388088,0.0000067997876,0.000111145324,0.00027015197,0.0000020257896],"category_scores_gemma":[0.0000962619,0.00016792116,0.00014250603,0.000059775586,0.000032314645,0.0000012678524,0.00039608325,0.000092268696,0.0000013998974],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013687418,0.00047351726,0.0025413178,0.24460088,0.0055328007,0.000053130952,0.0010156849,0.001534308,0.014158424,0.0030351805,0.05408894,0.6728289],"study_design_scores_gemma":[0.000180308,0.000054870612,0.000012861418,0.0010966663,0.00027172847,0.000021281276,0.000030935164,0.000014913991,0.000091618414,0.0000018161617,0.9980096,0.00021335892],"about_ca_topic_score_codex":0.000035028344,"about_ca_topic_score_gemma":0.0000023311682,"teacher_disagreement_score":0.94392073,"about_ca_system_score_codex":0.000020656133,"about_ca_system_score_gemma":0.00007429834,"threshold_uncertainty_score":0.6847626},"labels":[],"label_agreement":null},{"id":"W1982015434","doi":"10.1104/pp.002691","title":"Induction of Mitochondrial Alternative Oxidase in Response to a Cell Signal Pathway Down-Regulating the Cytochrome Pathway Prevents Programmed Cell Death","year":2002,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":205,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"National Institute on Aging","keywords":"Alternative oxidase; Cell biology; Biology; Programmed cell death; Mitochondrion; Biochemistry; Cytochrome c; Apoptosis","score_opus":0.013092838054554112,"score_gpt":0.24865945049947863,"score_spread":0.23556661244492452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982015434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982572,0.00015726435,0.00075848453,0.00003848533,0.00015555616,0.00048385785,0.00006517597,0.000008614354,0.00007532628],"genre_scores_gemma":[0.9984998,0.000016563523,0.00086764235,0.000040214003,0.00024092861,0.00009664659,0.000076662036,0.000016883281,0.00014462964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998763,0.00020667005,0.00027373643,0.00034519928,0.00010802849,0.00030335193],"domain_scores_gemma":[0.9994749,0.0000645938,0.000104376995,0.00025797926,0.000033606066,0.00006456864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001528559,0.0001733053,0.00019650067,0.000071551905,0.00004265248,0.000007556899,0.00020298653,0.00012783759,0.000022781298],"category_scores_gemma":[0.00004788072,0.00013671943,0.00007386855,0.00011159312,0.000038690352,0.000003691187,0.00010751293,0.00013121034,0.0000069677067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006598027,0.00016825128,0.000074929565,0.000022132122,0.000013423877,0.000004463993,0.0004902265,0.004358584,0.99321467,0.000004547767,0.00007155606,0.0009174164],"study_design_scores_gemma":[0.00095230434,0.00072733714,0.0042173523,0.000024369987,0.000006895425,0.000011338361,0.00009653717,0.0011639488,0.991537,0.000033810535,0.0010624254,0.00016672208],"about_ca_topic_score_codex":0.000047566456,"about_ca_topic_score_gemma":0.000022556127,"teacher_disagreement_score":0.0041424227,"about_ca_system_score_codex":0.000018298855,"about_ca_system_score_gemma":0.000028380286,"threshold_uncertainty_score":0.55752563},"labels":[],"label_agreement":null},{"id":"W1982257974","doi":"10.1089/hum.2013.063","title":"From Mutation Identification to Therapy: Discovery and Origins of the First Approved Gene Therapy in the Western World","year":2013,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Columbia university; Medicine; Library science; Hum; Family medicine; History; Art history; Media studies; Sociology","score_opus":0.014592525305170249,"score_gpt":0.28575485197025496,"score_spread":0.2711623266650847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982257974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99490124,0.002178891,0.0014585137,0.0006109844,0.00009943236,0.0007064913,0.000012075335,0.000006664484,0.00002570729],"genre_scores_gemma":[0.9975291,0.00092786865,0.00009932627,0.0007757955,0.00022354962,0.00014745281,0.000054985692,0.000023671508,0.00021824165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991644,0.000060372113,0.00022879224,0.00026875784,0.00013084296,0.00014685214],"domain_scores_gemma":[0.9993262,0.000017122007,0.000077818644,0.00051632046,0.00003834572,0.000024162435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014910685,0.00015089077,0.000119127864,0.000048082635,0.00008810225,0.00008464899,0.00031164696,0.00005471913,0.000012704126],"category_scores_gemma":[0.000003912592,0.00009476055,0.000060108683,0.0001354726,0.000049163755,0.000011134441,0.000033161163,0.0000642386,0.00000288371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004126685,0.00006240088,0.0058292714,0.0000025339414,0.000036682068,2.398526e-7,0.0017155934,0.00028060205,0.9848996,0.00001868922,0.00021841553,0.0068946956],"study_design_scores_gemma":[0.0007127874,0.00012454792,0.32082337,0.0000065495738,0.0000027321812,0.0000016195812,0.00009948309,0.00003085579,0.6708205,0.00019711348,0.007063212,0.00011721463],"about_ca_topic_score_codex":0.00060454593,"about_ca_topic_score_gemma":0.0005918582,"teacher_disagreement_score":0.31499413,"about_ca_system_score_codex":0.000013945392,"about_ca_system_score_gemma":0.000014096905,"threshold_uncertainty_score":0.38642234},"labels":[],"label_agreement":null},{"id":"W1983537316","doi":"10.1261/rna.051003.115","title":"Reflections for the 20th anniversary issue of <i>RNA</i> journal","year":2015,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; RNA; Computational biology; Transformative learning; Function (biology); Non-coding RNA; Genome; Genetics; Gene","score_opus":0.02329506258483296,"score_gpt":0.35596770316718485,"score_spread":0.3326726405823519,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983537316","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30780676,0.024260497,0.6300543,0.0034606173,0.003210034,0.00054163125,0.00006472906,0.000025892685,0.030575573],"genre_scores_gemma":[0.9948728,0.00031574958,0.0020645992,0.00013547693,0.0006783889,0.0000042341653,0.0000061160863,0.000009751245,0.0019128683],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997305,0.0000069795556,0.0000730436,0.00005884895,0.000048415477,0.000082174454],"domain_scores_gemma":[0.9997276,0.000008038975,0.000027195374,0.000115245086,0.00007799274,0.000043946537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124006,0.0000425577,0.000044971584,0.00001301672,0.000045743298,0.0000071806503,0.000090632566,0.00003499699,0.0000057989387],"category_scores_gemma":[0.000041895684,0.000031520667,0.000050966337,0.00003387899,0.000019559282,0.0000012342583,0.000021588909,0.00004150326,0.0000017204937],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007062874,0.000023134116,0.00005658272,0.000010849951,0.00007699363,0.0000011082352,0.00018877443,0.004384747,0.8328594,0.000042048796,0.15420866,0.008077106],"study_design_scores_gemma":[0.00026206943,0.00021213648,0.00009125636,0.000003958992,0.000022830009,0.000031885076,0.00030535946,0.00018127232,0.4305237,0.000067412526,0.56824523,0.000052882006],"about_ca_topic_score_codex":0.000007327776,"about_ca_topic_score_gemma":0.0000068713475,"teacher_disagreement_score":0.6870661,"about_ca_system_score_codex":0.0000049387922,"about_ca_system_score_gemma":0.000040521038,"threshold_uncertainty_score":0.12853755},"labels":[],"label_agreement":null},{"id":"W1983740928","doi":"10.1038/ncomms1601","title":"BRCA1 is an essential regulator of heart function and survival following myocardial infarction","year":2011,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa; Hospital for Sick Children; McMaster University; University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Sanofi; AstraZeneca; Pfizer","keywords":"DNA damage; Heart failure; Apoptosis; Cancer research; Myocardial infarction; Regulator; Cardiac function curve; Biology; Medicine; DNA repair; Breast cancer; Internal medicine; Cell biology; Cancer; Cardiology; Gene; DNA; Genetics","score_opus":0.014089690531696324,"score_gpt":0.30240795624194955,"score_spread":0.2883182657102532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983740928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928966,0.0031896376,0.0023317242,0.00018701739,0.0004521047,0.00009980138,0.000010427762,0.000015995296,0.00081666966],"genre_scores_gemma":[0.99609387,0.00016837784,0.003444262,0.000082854975,0.00008803029,0.000006776929,0.0000828623,0.000010541752,0.000022418582],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995835,0.000043438413,0.00010874402,0.0001256141,0.00006470652,0.00007399893],"domain_scores_gemma":[0.99916786,0.000007365633,0.00002967767,0.0007014201,0.000055063087,0.00003861493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011825272,0.000066611254,0.00007861145,0.00003155755,0.00008013285,0.0000069392886,0.00015895964,0.0001846961,0.0000054063926],"category_scores_gemma":[0.000025180869,0.000072165814,0.00006162041,0.00006461952,0.00004538533,0.0000063000016,0.000117538584,0.00014543526,6.4338656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051552783,0.000088686145,0.0369647,0.000009047828,0.00014127533,6.544985e-8,0.00029739336,0.000011518993,0.9592342,0.0012287295,0.00084742665,0.001125401],"study_design_scores_gemma":[0.0007097412,0.00029802296,0.75727147,0.00001547959,0.00014798199,0.0000071469844,0.00030096536,0.00032346125,0.19152983,0.00031149387,0.04880407,0.00028036363],"about_ca_topic_score_codex":0.000030764142,"about_ca_topic_score_gemma":0.00010285541,"teacher_disagreement_score":0.76770437,"about_ca_system_score_codex":0.0000034309603,"about_ca_system_score_gemma":0.000017714396,"threshold_uncertainty_score":0.29428366},"labels":[],"label_agreement":null},{"id":"W1984073046","doi":"10.1007/s12015-010-9226-2","title":"Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party","year":2011,"lang":"en","type":"article","venue":"Stem Cell Reviews and Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Juvenile Diabetes Research Foundation; McGill University","funders":"","keywords":"Embryonic stem cell; Context (archaeology); Bioethics; Research ethics; Economic Justice; Beneficence; Statement (logic); Stem cell; Biology; Autonomy; Political science; Genetics; Law; Biotechnology","score_opus":0.053739145543964896,"score_gpt":0.3204832153300351,"score_spread":0.2667440697860702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984073046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9117135,0.073603615,0.0010341284,0.00018160605,0.0008582484,0.00074482604,0.000013852743,0.000011276927,0.011838982],"genre_scores_gemma":[0.9877309,0.009022371,0.0002070003,0.000081631115,0.00013047206,0.000017218463,0.000018269946,0.000023123377,0.0027689799],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824226,0.00008734907,0.0008786194,0.00033378004,0.00022976818,0.00022825303],"domain_scores_gemma":[0.9984723,0.000015611287,0.0007911632,0.00050201087,0.0001458001,0.00007316227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010415479,0.00019268213,0.00031312014,0.00005042708,0.00008864101,0.00004146463,0.0002524996,0.00016786449,0.00000988053],"category_scores_gemma":[0.000012153025,0.00013314607,0.0001706913,0.0001159967,0.00005298297,0.000011140054,0.00030535564,0.00020251231,4.9919163e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020054682,0.00020879135,0.022044053,0.0028837698,0.00009965152,0.000017157534,0.0031834315,0.00017906442,0.9410473,0.00016827317,0.0030216963,0.027126746],"study_design_scores_gemma":[0.00019848817,0.000111057554,0.0007103386,0.0003002869,0.000054379107,0.000017758039,0.0008190479,0.00001673374,0.83065146,0.000033404373,0.1668859,0.00020117062],"about_ca_topic_score_codex":0.000080563026,"about_ca_topic_score_gemma":0.00006602173,"teacher_disagreement_score":0.16386421,"about_ca_system_score_codex":0.00001829212,"about_ca_system_score_gemma":0.00013598222,"threshold_uncertainty_score":0.5429539},"labels":[],"label_agreement":null},{"id":"W1985941121","doi":"10.1534/genetics.114.170217","title":"Understanding Rare Disease Pathogenesis: A Grand Challenge for Model Organisms","year":2014,"lang":"en","type":"letter","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Canada's Michael Smith Genome Sciences Centre; Children's Hospital of Eastern Ontario; University of British Columbia","funders":"","keywords":"Biology; Genetics; Pathogenesis; Disease; Evolutionary biology; Immunology; Pathology; Medicine","score_opus":0.057943900059833,"score_gpt":0.2857735873205498,"score_spread":0.2278296872607168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985941121","genre_codex":"methods","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00079843996,0.0062835873,0.9475733,0.043321427,0.0004547402,0.00078246655,0.00051480083,0.00005140677,0.00021983765],"genre_scores_gemma":[0.4236354,0.010301451,0.043100514,0.46875125,0.028993249,0.0011075125,0.014335575,0.0017344574,0.008040617],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99809414,0.00003510186,0.0003092387,0.0007390973,0.00023793493,0.00058450486],"domain_scores_gemma":[0.9988208,0.000022497768,0.00010499493,0.00079076656,0.00009205182,0.00016890271],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001146483,0.00048273822,0.00033724777,0.000082275365,0.00013422967,0.000056959198,0.00037688977,0.00079643086,0.000008749132],"category_scores_gemma":[0.000041366013,0.00051542174,0.000278454,0.000051076953,0.000058362297,0.0000012611525,0.0001315678,0.00027919564,0.000005991062],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057405196,0.000029740198,0.000027257309,0.0008182196,0.00017515752,0.000031532367,0.000069691356,0.01927123,0.027271207,0.000055705834,0.9518222,0.00037063213],"study_design_scores_gemma":[0.0010853839,0.00029449273,0.000011006107,0.00008740312,0.00038812208,0.000015878226,0.000028740596,0.017630436,0.009478917,0.0023954099,0.96738553,0.0011986562],"about_ca_topic_score_codex":3.8023876e-7,"about_ca_topic_score_gemma":0.0000074624463,"teacher_disagreement_score":0.90447277,"about_ca_system_score_codex":0.000043442273,"about_ca_system_score_gemma":0.00014770472,"threshold_uncertainty_score":0.99972975},"labels":[],"label_agreement":null},{"id":"W1986247529","doi":"10.1371/journal.pone.0037130","title":"Rapid Transcriptional Pulsing Dynamics of High Expressing Retroviral Transgenes in Embryonic Stem Cells","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Amgen (Canada); Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Biology; Embryonic stem cell; Transgene; Stem cell; Transcription (linguistics); Transfection; Molecular biology; Gene; Cell biology; HEK 293 cells; Genetics","score_opus":0.02151587818045043,"score_gpt":0.2370723715286457,"score_spread":0.21555649334819527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986247529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98928386,0.004384382,0.005966318,0.00004107208,0.000084720814,0.00009855891,0.000030231951,0.000007922262,0.000102934195],"genre_scores_gemma":[0.996349,0.0002493072,0.0029952799,0.000014945502,0.00014785142,0.0000081678145,0.00005197375,0.000021803202,0.0001616887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924475,0.000028653567,0.00018979251,0.00014996516,0.00013913457,0.00024769956],"domain_scores_gemma":[0.99971753,0.000007226917,0.000035359393,0.00016039572,0.000025541933,0.000053966123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119675984,0.00010969618,0.00016432047,0.000051103958,0.000021675793,0.0000070813808,0.00009170412,0.000104624974,0.000018430514],"category_scores_gemma":[0.0000035410098,0.00012111131,0.000057327627,0.00006592583,0.00003069723,0.0000067826704,0.000015910875,0.000078646764,0.0000013152493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040249528,0.00028791107,0.0022687055,0.00011702565,0.000055921144,3.5513932e-7,0.00011052587,0.0003532574,0.99452794,0.00005519588,0.000004644043,0.0021783004],"study_design_scores_gemma":[0.0003939507,0.00009552024,0.004171318,0.00007804942,0.000043395536,0.000001361123,0.00007082528,0.00085342565,0.9940748,0.000009157099,0.00006933553,0.00013886664],"about_ca_topic_score_codex":0.000010972577,"about_ca_topic_score_gemma":0.000019238401,"teacher_disagreement_score":0.007065123,"about_ca_system_score_codex":0.000019270266,"about_ca_system_score_gemma":0.000018366727,"threshold_uncertainty_score":0.49387762},"labels":[],"label_agreement":null},{"id":"W1987327863","doi":"10.1139/o08-111","title":"YEATS domain proteins: a diverse family with many links to chromatin modification and transcriptionThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.","year":2009,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"","keywords":"Chromatin; Biology; Domain (mathematical analysis); Saccharomyces cerevisiae; Genetics; Lineage (genetic); Gene; Computational biology; Protein domain; Cell biology","score_opus":0.014159683653453405,"score_gpt":0.2858420768035482,"score_spread":0.2716823931500948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987327863","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.056027442,0.94165444,0.00024960868,0.0003874293,0.00003498157,0.0008715378,0.00014391569,0.0000051440784,0.000625517],"genre_scores_gemma":[0.025559224,0.97254276,0.00090231444,0.00008165974,0.0002506185,0.00003872433,0.00020067728,0.000021779551,0.00040223132],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99856615,0.00011289596,0.00055706705,0.0004180964,0.00014745994,0.00019833983],"domain_scores_gemma":[0.9991879,0.000022601365,0.00033698182,0.00018260219,0.00018176292,0.00008814032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053720473,0.00030201024,0.00066826364,0.00006678095,0.00008606819,0.000029438224,0.00013063883,0.00050443836,0.00014035305],"category_scores_gemma":[0.00008937112,0.00022899074,0.000060938874,0.00016165953,0.00020982146,0.000008734613,0.000056627407,0.00028464268,2.1167311e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017179482,0.00020809485,0.000117432835,0.031458564,0.0002826487,0.0000024934939,0.0012144428,0.0000074222808,0.72051394,0.000008719271,0.0017145647,0.24429986],"study_design_scores_gemma":[0.003780559,0.0034831716,0.00092801906,0.026786014,0.0023165839,0.00043726448,0.0032972759,0.00019123823,0.266169,0.00009313054,0.69037694,0.002140769],"about_ca_topic_score_codex":0.000032781594,"about_ca_topic_score_gemma":0.000052756488,"teacher_disagreement_score":0.6886624,"about_ca_system_score_codex":0.000025079215,"about_ca_system_score_gemma":0.00012887186,"threshold_uncertainty_score":0.9337971},"labels":[],"label_agreement":null},{"id":"W1988248658","doi":"10.1093/nar/gni093","title":"A complementation method for functional analysis of mammalian genes","year":2005,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness","keywords":"Biology; Complementation; Genetics; Gene; Gene targeting; Mutant; Genetic screen","score_opus":0.0618234255584698,"score_gpt":0.44991601624108896,"score_spread":0.38809259068261914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988248658","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4826653,0.00031710626,0.516134,0.00023383132,0.000028703269,0.00017963184,0.000056251854,0.0000049270047,0.00038022303],"genre_scores_gemma":[0.9389201,0.00003647,0.05986475,0.00003208118,0.00020121707,0.000043596014,0.00028731147,0.0000119895,0.0006025052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991746,0.00005386572,0.00015572242,0.00019912496,0.00021830486,0.00019839877],"domain_scores_gemma":[0.9994852,0.000036120964,0.000018782766,0.00019211989,0.00022034759,0.000047454643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063666614,0.000059839964,0.000107429994,0.00020825228,0.000068300906,0.000011368915,0.00010968219,0.00005681292,0.00017636378],"category_scores_gemma":[0.000050381936,0.000060203067,0.000113212096,0.00032994425,0.000036224945,0.0000021474357,0.00005745305,0.000048962836,0.0000036977226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085603664,0.000038843707,0.0028857156,0.000020943344,0.00034483743,1.0874984e-7,0.00006256989,0.014760432,0.9396298,0.0003104456,0.0019935837,0.039867133],"study_design_scores_gemma":[0.0006943317,0.0003054153,0.042824835,0.0000032022883,0.00015651667,0.0000016964634,0.00032755465,0.07002477,0.75893503,0.000042933738,0.12654535,0.00013832703],"about_ca_topic_score_codex":0.000026676824,"about_ca_topic_score_gemma":0.00013460944,"teacher_disagreement_score":0.45626926,"about_ca_system_score_codex":0.00001564744,"about_ca_system_score_gemma":0.000029899547,"threshold_uncertainty_score":0.24550098},"labels":[],"label_agreement":null},{"id":"W1989600290","doi":"10.1016/j.socscimed.2011.06.041","title":"Institutional policy learning and public consultation: The Canadian xenotransplantation experience","year":2011,"lang":"en","type":"article","venue":"Social Science & Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Women's Health In Women's Hands; University of Calgary; University of Saskatchewan","funders":"Health Canada","keywords":"Bureaucracy; Public consultation; Openness to experience; Public policy; Citizen journalism; Public administration; Public relations; Political science; Democracy; Public participation; Deliberative democracy; Policy advocacy; Institutionalisation; Deliberation; Sociology; Psychology; Law; Politics; Social psychology","score_opus":0.020428813301192353,"score_gpt":0.32959402654058195,"score_spread":0.3091652132393896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989600290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97610927,0.000271124,0.00231497,0.0017609274,0.00013429651,0.00008055059,0.0000017916074,0.000007452167,0.019319613],"genre_scores_gemma":[0.9993055,0.00005594069,0.00003574356,0.0002683556,0.0002659927,0.0000069138437,0.0000084610765,0.0000020764817,0.000051000145],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99949825,0.000011610937,0.000063748616,0.00012253184,0.0001365542,0.00016729531],"domain_scores_gemma":[0.9997629,0.0000048168336,0.000016821612,0.000037215297,0.00007481742,0.00010345335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020336572,0.00004510766,0.000035361343,0.000051197363,0.00075621577,0.000015806369,0.00010125997,0.000030858824,0.000021361784],"category_scores_gemma":[0.0002515335,0.000032817636,0.0000070572996,0.00024515545,0.0011582902,0.000006857252,0.000011023414,0.00005216397,8.007476e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029648,0.00002111802,0.089289665,0.000021864633,0.000022079626,0.0000091139555,0.184735,0.00003587624,0.5821663,0.0819161,0.00022174722,0.061531506],"study_design_scores_gemma":[0.0024264655,0.0005619619,0.6988533,0.000058988386,0.00004842521,0.0002213576,0.037604485,0.00056916714,0.081506364,0.0014771753,0.17588091,0.0007913575],"about_ca_topic_score_codex":0.014902449,"about_ca_topic_score_gemma":0.014536408,"teacher_disagreement_score":0.60956365,"about_ca_system_score_codex":0.000024682764,"about_ca_system_score_gemma":0.00039866855,"threshold_uncertainty_score":0.9916574},"labels":[],"label_agreement":null},{"id":"W19897740","doi":"10.3138/jcs.37.3.162","title":"The Biopolitics of Genetically Modified Organisms in Canada","year":2002,"lang":"en","type":"article","venue":"Journal of Canadian Studies","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biopower; Framing (construction); Politics; Genetically modified organism; Environmental ethics; Eugenics; Precautionary principle; Biosafety; Political science; Political economy; Law and economics; Sociology; Biotechnology; Law; Biology; History","score_opus":0.01712996488517077,"score_gpt":0.25838170490305845,"score_spread":0.24125174001788768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W19897740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9723354,0.024919711,0.00006819796,0.0011675392,0.0002962404,0.00004171337,0.000009200893,3.5494062e-7,0.0011616518],"genre_scores_gemma":[0.9944659,0.0050454894,0.00017006796,0.00010904453,0.000085507876,5.685495e-7,2.3675852e-7,0.0000061601386,0.00011701282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939185,0.000014008931,0.00025868518,0.000048661175,0.00010168721,0.00018508128],"domain_scores_gemma":[0.9995569,0.00002329058,0.000063446234,0.000097607975,0.00014826121,0.00011050789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009514181,0.00006234913,0.00012537616,0.000083460276,0.00003845418,0.0000044778017,0.00012652295,0.000025336622,0.000004384407],"category_scores_gemma":[0.00014485244,0.00004561763,0.000031533964,0.00010968223,0.000048071935,8.604799e-7,0.000017392027,0.00006192587,2.090002e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016736453,0.00016140087,0.071265355,0.0003667511,0.0041027865,0.0009145562,0.0046297726,0.054147042,0.4726714,0.007042574,0.30932936,0.075201645],"study_design_scores_gemma":[0.0028464713,0.0011317533,0.08551901,0.00019659367,0.00019029947,0.00046533818,0.016378893,0.0012405617,0.46191642,0.00083383336,0.4283285,0.0009523176],"about_ca_topic_score_codex":0.48807472,"about_ca_topic_score_gemma":0.99221516,"teacher_disagreement_score":0.50414044,"about_ca_system_score_codex":0.00009410704,"about_ca_system_score_gemma":0.00048594718,"threshold_uncertainty_score":0.51533425},"labels":[],"label_agreement":null},{"id":"W1991459016","doi":"10.1016/j.ymthe.2004.04.007","title":"Retrovirus Silencing, Variegation, Extinction, and Memory Are Controlled by a Dynamic Interplay of Multiple Epigenetic Modifications","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Variegation (histology); Epigenetics; Gene silencing; Extinction (optical mineralogy); Biology; Retrovirus; Neuroscience; Genetics; Gene","score_opus":0.004064821540697614,"score_gpt":0.2625802961656503,"score_spread":0.2585154746249527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991459016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7667619,0.007218554,0.22549343,0.0000901122,0.00005475233,0.00028577456,0.00001658474,0.00001298011,0.000065930675],"genre_scores_gemma":[0.9973781,0.0008658018,0.0013525785,0.0001357819,0.00001878279,0.000066656256,0.00005640286,0.00002833603,0.000097545475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991678,0.000039186398,0.00025408363,0.00028241272,0.00010557573,0.00015094514],"domain_scores_gemma":[0.99939775,0.0000121049825,0.00011177573,0.00032103903,0.000096712174,0.000060623915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010479022,0.00015554726,0.00019502078,0.00005199125,0.000057656536,0.000015452988,0.000111482674,0.00010600898,0.000010160019],"category_scores_gemma":[0.000074292235,0.00015369494,0.00008527527,0.00008086308,0.00006652302,0.0000029866592,0.000025351846,0.00006313355,0.0000022352092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017057518,0.00006888774,0.00016080184,0.000009850803,0.00008636148,0.0000011368155,0.00012614677,0.0047955206,0.99283546,0.000012300566,0.000028824219,0.0017041465],"study_design_scores_gemma":[0.0047522034,0.00023874617,0.0020395194,0.000016471424,0.000020843596,0.000009030718,0.000120540986,0.0010218376,0.99074256,0.00020843248,0.000644079,0.00018571208],"about_ca_topic_score_codex":0.000035030782,"about_ca_topic_score_gemma":0.00002651172,"teacher_disagreement_score":0.23061624,"about_ca_system_score_codex":0.000016895965,"about_ca_system_score_gemma":0.000034939425,"threshold_uncertainty_score":0.6267498},"labels":[],"label_agreement":null},{"id":"W1991811105","doi":"10.1159/000130297","title":"Characteristics of an HPRT-deficient Chinese hamster cell line","year":2008,"lang":"en","type":"article","venue":"Cytogenetics and Cell Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Chinese hamster; Doubling time; Molecular biology; Biology; Hypoxanthine-guanine phosphoribosyltransferase; Mutant; Cell culture; Chromosome; Karyotype; Genetics; Gene","score_opus":0.008451517454796215,"score_gpt":0.2554132324283956,"score_spread":0.24696171497359937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991811105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98955196,0.0053197397,0.004033515,0.000010424895,0.00022625517,0.00019610803,0.00007316565,0.000013336188,0.0005755099],"genre_scores_gemma":[0.9870253,0.0070484695,0.0047993,0.000098734134,0.00030272076,0.000009173699,0.00014537964,0.00006492248,0.0005059763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984619,0.000035154022,0.00045533752,0.0004689541,0.00021488583,0.00036374902],"domain_scores_gemma":[0.99881965,0.000011489826,0.00013642224,0.00064047985,0.0001488083,0.000243144],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011071724,0.0003235754,0.00029946837,0.00007246308,0.00010836196,0.00002009238,0.00025197913,0.00021643376,0.000018746052],"category_scores_gemma":[0.000014024537,0.00031467128,0.0001027341,0.00012098509,0.00016583754,0.0000025768068,0.00020381212,0.00010923745,0.000005032451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003463582,0.00027160696,0.05082021,0.00010769741,0.000018673274,0.000011942988,0.00034740084,0.00096238696,0.9452396,0.0000027622964,0.00008509653,0.0020980036],"study_design_scores_gemma":[0.00082206714,0.0010676334,0.069171965,0.000008059815,0.000048207807,0.00007014989,0.000052483436,0.0019587383,0.9198972,0.00001838199,0.00643476,0.00045034225],"about_ca_topic_score_codex":0.000004353215,"about_ca_topic_score_gemma":0.000004761738,"teacher_disagreement_score":0.025342379,"about_ca_system_score_codex":0.0000061801125,"about_ca_system_score_gemma":0.00006766275,"threshold_uncertainty_score":0.99993056},"labels":[],"label_agreement":null},{"id":"W1992310655","doi":"10.1371/journal.pone.0047259","title":"Boundaries of the Origin of Replication: Creation of a pET-28a-Derived Vector with p15A Copy Control Allowing Compatible Coexistence with pET Vectors","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Ontario Innovation Trust; California HIV/AIDS Research Program","keywords":"Replicon; Plasmid; PBR322; Biology; Origin of replication; Genetics; Cloning vector; Multiple cloning site; Vector (molecular biology); DNA replication; Molecular biology; DNA; Gene; Recombinant DNA","score_opus":0.017538159773246343,"score_gpt":0.2625208597136745,"score_spread":0.24498269994042815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992310655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951007,0.00034469494,0.0040032654,0.000055056462,0.000018566225,0.00024233751,0.00002197847,0.000005820283,0.0002076201],"genre_scores_gemma":[0.9963905,0.000018013634,0.003437456,0.000013534933,0.0000379955,0.000020595795,0.000022845952,0.000012686951,0.00004637864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936783,0.000025444497,0.00017491911,0.00013378293,0.00018031408,0.00011770602],"domain_scores_gemma":[0.9992253,0.000019840361,0.000149721,0.00040751856,0.00016502036,0.00003260461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010151582,0.00009073098,0.00019771524,0.000017673767,0.000044124317,0.0000068785034,0.00011147858,0.000022673501,0.000008743555],"category_scores_gemma":[0.000054635482,0.000063777814,0.000033130214,0.000091046524,0.00019117155,0.0000053903323,0.000020647056,0.00004132279,2.6701414e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018522849,0.00020939157,0.08919577,0.00013883419,0.00020349007,1.6752776e-7,0.00026568174,0.00018108415,0.9094882,0.000105769825,0.0000119828355,0.000014396102],"study_design_scores_gemma":[0.00060716784,0.00036110132,0.049719725,0.00014031384,0.00013371889,0.000005334216,0.00009761329,0.00019631031,0.9485053,0.0000021551707,0.00014975277,0.00008152318],"about_ca_topic_score_codex":0.000053074793,"about_ca_topic_score_gemma":0.000033474174,"teacher_disagreement_score":0.03947605,"about_ca_system_score_codex":0.000008236454,"about_ca_system_score_gemma":0.000070763286,"threshold_uncertainty_score":0.2600784},"labels":[],"label_agreement":null},{"id":"W1993315391","doi":"10.1038/nmeth.1332","title":"Transposon-mediated genome manipulation in vertebrates","year":2009,"lang":"en","type":"review","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":318,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Transposable element; Biology; Insertional mutagenesis; Genome; Sleeping Beauty transposon system; Genetics; Mutagenesis; Transposon mutagenesis; Germline; Computational biology; Somatic cell; Gene; Mutation","score_opus":0.023300624692241364,"score_gpt":0.4422384076659385,"score_spread":0.41893778297369716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993315391","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000013330299,0.9757178,0.023149183,0.0000099129,0.0002746233,0.00034187926,0.00002214602,0.000018037776,0.00045310572],"genre_scores_gemma":[0.00006855036,0.9626538,0.03543754,0.00006074122,0.00030911446,0.000027203036,0.0012430705,0.000049214104,0.00015075786],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985796,0.00026491226,0.00036676228,0.00044406846,0.00009279414,0.0002518424],"domain_scores_gemma":[0.9994304,0.000050973038,0.00008080987,0.00034902393,0.00002742905,0.00006133985],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004664065,0.00033953539,0.00070835795,0.0001651971,0.000019557137,0.000015638312,0.00023885771,0.0014700955,0.000016561171],"category_scores_gemma":[0.00013252931,0.00030166295,0.0002700866,0.0002958793,0.000013472893,0.0000016205967,0.000025694422,0.0007039423,0.0000065245918],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000052728196,0.000019990268,0.0000025735576,0.0013665576,0.000050544055,0.0000066758594,0.000012010237,0.000052786698,0.00439067,0.000014413974,0.0000635803,0.9940149],"study_design_scores_gemma":[0.00014392483,0.0000534384,0.00011938122,0.00051780837,0.00011315104,0.000017425962,0.0000018828333,0.00004452029,0.00068447826,0.00002832172,0.99794436,0.00033133864],"about_ca_topic_score_codex":0.0000020022005,"about_ca_topic_score_gemma":0.0000116401725,"teacher_disagreement_score":0.99788076,"about_ca_system_score_codex":0.000030732157,"about_ca_system_score_gemma":0.00007317168,"threshold_uncertainty_score":0.99994355},"labels":[],"label_agreement":null},{"id":"W1993658572","doi":"10.1016/j.mimet.2010.07.002","title":"Mini-Tn7 vectors as genetic tools for single copy gene cloning in Acinetobacter baumannii","year":2010,"lang":"en","type":"article","venue":"Journal of Microbiological Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ontario Institute of Technology","funders":"University of Ontario Institute of Technology; Colorado State University","keywords":"Acinetobacter baumannii; Biology; Gene; Genetics; Cloning (programming); Pathogen; Bacteria","score_opus":0.027003065323015423,"score_gpt":0.39473166753934746,"score_spread":0.367728602216332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993658572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9178878,0.0011203372,0.07989854,0.000084927095,0.00072969886,0.00016172664,0.00000903507,0.000004801702,0.00010310806],"genre_scores_gemma":[0.6136815,0.000087692446,0.38555068,0.00014899965,0.00044798022,0.000006064783,0.0000118831895,0.00001581974,0.000049385028],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986954,0.00014641821,0.00053888635,0.0002502244,0.000051240462,0.00031787902],"domain_scores_gemma":[0.9991551,0.00021354678,0.00019541284,0.00019638818,0.000129533,0.00011001467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094223174,0.00019271679,0.00034339307,0.00008325194,0.00003751711,0.000041237334,0.00028378633,0.00032993732,0.000050209186],"category_scores_gemma":[0.0011794466,0.00014780805,0.00022786022,0.00008316746,0.00006562867,0.0000063896196,0.00007960741,0.00032043652,0.0000020393345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014757329,0.00007546869,0.001270638,0.00000986225,0.00003674404,0.000009208273,0.000027614056,0.0002502652,0.9776578,0.0000056632566,0.00022724141,0.020281954],"study_design_scores_gemma":[0.00076333736,0.0011369253,0.008317958,0.000016381602,0.00002511479,0.00048307003,0.00003135716,0.000018049182,0.94182277,0.000091775255,0.047098827,0.00019444816],"about_ca_topic_score_codex":0.0000022111574,"about_ca_topic_score_gemma":0.0000056348345,"teacher_disagreement_score":0.30565214,"about_ca_system_score_codex":0.000016320293,"about_ca_system_score_gemma":0.00004568859,"threshold_uncertainty_score":0.60274374},"labels":[],"label_agreement":null},{"id":"W1993903060","doi":"10.1038/nprot.2014.105","title":"Generation of a transgenic ORFeome library in Drosophila","year":2014,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"ORFS; Biology; Open reading frame; RNA interference; Drosophila melanogaster; Genetics; Integrase; Computational biology; Transgene; Genomic library; Gene; Genetic screen; Plasmid; Schneider 2 cells; Function (biology); Mutant; RNA; Peptide sequence","score_opus":0.012574502015497018,"score_gpt":0.32630708432824923,"score_spread":0.3137325823127522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993903060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9591843,0.0006179931,0.0077948384,0.00037647027,0.00012083367,0.029078718,0.000017458431,0.00003289688,0.0027764854],"genre_scores_gemma":[0.99091893,0.000007427625,0.0015514551,0.000120735094,0.0002794264,0.0069375252,0.000042980493,0.000016132833,0.00012539231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948967,0.000026576387,0.00014544181,0.00016391215,0.00007021466,0.000104216735],"domain_scores_gemma":[0.99973667,0.000004035798,0.000027571587,0.0001887578,0.00001533958,0.000027643302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009024941,0.00008024016,0.00009595141,0.000041619172,0.000009955299,0.000008183993,0.00010999298,0.00024264031,0.000012298708],"category_scores_gemma":[0.000027075941,0.000075830845,0.000045523462,0.000087869004,0.000013603007,0.0000032642383,0.0000221699,0.00013432463,0.0000011511045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003452392,0.000030426587,0.0017318679,0.00005596419,0.000005555873,2.6628257e-7,0.000019656645,0.00045040957,0.9951835,0.00030454763,0.0006436988,0.0015395809],"study_design_scores_gemma":[0.00055638043,0.0001761777,0.003446889,0.000027207087,0.0000021277544,0.0000018200177,0.0000016019894,0.0004912339,0.94922537,0.00012767957,0.045848105,0.00009543406],"about_ca_topic_score_codex":7.90311e-7,"about_ca_topic_score_gemma":0.000007103584,"teacher_disagreement_score":0.045958158,"about_ca_system_score_codex":0.0000022588908,"about_ca_system_score_gemma":0.00002281994,"threshold_uncertainty_score":0.30922922},"labels":[],"label_agreement":null},{"id":"W1994029368","doi":"10.1016/j.stem.2010.06.024","title":"Female Human iPSCs Retain an Inactive X Chromosome","year":2010,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":285,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; XIST; Reprogramming; Induced pluripotent stem cell; X-inactivation; Epigenome; Chromatin; Embryonic stem cell; X chromosome; Genetics; Cell biology; Gene; Gene expression; DNA methylation","score_opus":0.0077282005624466615,"score_gpt":0.27062120139597523,"score_spread":0.26289300083352857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994029368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97554207,0.00031585555,0.00074728526,0.0000078298135,0.00023506611,0.00014292863,0.000009424559,0.000025648827,0.022973908],"genre_scores_gemma":[0.9928519,0.000024295785,0.00047228817,0.00004245397,0.0003659492,0.000013908202,0.00010094657,0.000037968475,0.0060902587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991088,0.000024238963,0.00014848005,0.00036313757,0.00009009592,0.00026527213],"domain_scores_gemma":[0.9992505,0.000005316479,0.000048080794,0.0005120645,0.000042078595,0.00014197027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117312615,0.00016929077,0.00012500207,0.000030074349,0.0000939688,0.000028372842,0.0002234568,0.00019292273,0.000065560474],"category_scores_gemma":[0.0000022635695,0.0001749303,0.000068713496,0.000054465152,0.00004350902,0.000003910906,0.00008354365,0.00018974119,0.00004841802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000070281494,0.000076598524,0.0005201118,0.000034279255,0.000005796061,0.0000052419427,0.00015922649,0.000069048954,0.9982873,0.000028599636,0.00028904842,0.00051772513],"study_design_scores_gemma":[0.00032784772,0.00024628008,0.0006670842,0.0000027856204,0.000011948992,0.0000060655157,0.0003117181,0.00007827277,0.9679196,0.00001389091,0.030178914,0.00023558948],"about_ca_topic_score_codex":0.0000114840495,"about_ca_topic_score_gemma":0.000058419762,"teacher_disagreement_score":0.030367693,"about_ca_system_score_codex":0.0000087021035,"about_ca_system_score_gemma":0.000033643224,"threshold_uncertainty_score":0.71334505},"labels":[],"label_agreement":null},{"id":"W1994138031","doi":"10.1007/s12033-010-9244-y","title":"Development of Chimeric Gene Regulators for Cancer-specific Gene Therapy with both Transcriptional and Translational Targeting","year":2010,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"State Key Laboratory of Genetic Engineering; University of British Columbia; Fudan University","keywords":"Biology; Genetic enhancement; Untranslated region; Enhancer; Transcriptional regulation; Gene; Chimeric gene; Transfection; Gene expression; Regulation of gene expression; Cancer research; Suicide gene; Regulator; Translational efficiency; Three prime untranslated region; YY1; Molecular biology; Promoter; Messenger RNA; Genetics; Translation (biology)","score_opus":0.006101142208465945,"score_gpt":0.24649086619040667,"score_spread":0.24038972398194072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994138031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7440135,0.0037075914,0.25177458,0.00020627656,0.00006580409,0.00019103177,0.000019427025,0.000015760888,0.0000060272027],"genre_scores_gemma":[0.8074374,0.00031769267,0.1919754,0.000030181067,0.00004500913,0.000061745304,0.00009678778,0.000026113075,0.00000967902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991845,0.0000067282463,0.00019758742,0.00032056542,0.00009185507,0.00019876583],"domain_scores_gemma":[0.999681,0.0000037907375,0.00005334655,0.00017480174,0.000046553174,0.000040491952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009121173,0.00015526946,0.00014539172,0.0000777882,0.00006758179,0.000005949933,0.000118686534,0.00025472962,0.000009615814],"category_scores_gemma":[0.0000044849044,0.00014413633,0.000047851187,0.000093291485,0.00013257652,0.0000019271424,0.000017049075,0.000104312516,1.5063745e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007872767,0.000029411332,0.0002175107,0.000012194843,0.00007846591,7.657508e-7,0.000054069034,0.00023024327,0.9817416,0.0007002022,0.000009156645,0.016847635],"study_design_scores_gemma":[0.0007423973,0.00012023945,0.0023369591,0.000004050256,0.00000829003,0.000019422916,0.000014298198,0.0001026861,0.9556251,0.000054183958,0.040797338,0.00017500992],"about_ca_topic_score_codex":0.0000024246444,"about_ca_topic_score_gemma":0.000025286257,"teacher_disagreement_score":0.063423894,"about_ca_system_score_codex":0.0000033097572,"about_ca_system_score_gemma":0.00007429146,"threshold_uncertainty_score":0.58777094},"labels":[],"label_agreement":null},{"id":"W1994248072","doi":"10.3389/fgene.2014.00259","title":"Freedom in bioinformatics","year":2014,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire de Cardiologie et de Pneumologie de Québec; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Genomics; Computer science; Genome; Computational biology; Bioinformatics; Biology; Data science; Genetics; Gene","score_opus":0.003547129598868935,"score_gpt":0.23941144187699845,"score_spread":0.2358643122781295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994248072","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4868784,0.0023117021,0.50592923,0.000055521592,0.0010729309,0.00018256516,0.000005421853,0.000012752046,0.003551452],"genre_scores_gemma":[0.8599053,0.0005899417,0.13898213,0.00011194961,0.0001749168,0.000011898013,0.000032810487,0.00002338569,0.00016765526],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9992071,0.000023103532,0.0002467476,0.00017234695,0.00008881291,0.000261938],"domain_scores_gemma":[0.9995928,0.000004736645,0.00002999184,0.00030157482,0.000016822221,0.000054080025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017820211,0.000124046,0.00013722105,0.000119533775,0.000014649425,0.000013136404,0.00018803138,0.00013370128,0.0000033848517],"category_scores_gemma":[0.000055227865,0.00013665906,0.000037067955,0.00013467271,0.00004047847,0.0000017042148,0.00007078422,0.000091900736,0.000004584985],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006861026,0.00013857188,0.5823929,0.00013227119,0.000042505675,0.0000059324498,0.0006239707,0.25731868,0.034668867,0.00013022304,0.03059238,0.093885146],"study_design_scores_gemma":[0.003395901,0.0005270929,0.11452539,0.000076595265,0.000020961083,0.00001597568,0.00068424107,0.49651295,0.08296808,0.0007282106,0.29944298,0.001101625],"about_ca_topic_score_codex":0.000006412221,"about_ca_topic_score_gemma":0.000060808783,"teacher_disagreement_score":0.46786746,"about_ca_system_score_codex":0.000016051568,"about_ca_system_score_gemma":0.00002084749,"threshold_uncertainty_score":0.55727947},"labels":[],"label_agreement":null},{"id":"W1994659642","doi":"10.1016/j.mrfmmm.2006.01.017","title":"Detection of induced male germline mutation: Correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays","year":2006,"lang":"en","type":"review","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Health Canada","funders":"","keywords":"Germline; Germline mutation; Biology; Mutation; Genetics; Transgene; Tandem repeat; Genome; Gene","score_opus":0.07910991897464491,"score_gpt":0.3757448740915625,"score_spread":0.29663495511691756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994659642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4649471,0.27253968,0.25951868,0.00004297068,0.000107120795,0.0018070072,0.0009558181,0.000028251714,0.000053356427],"genre_scores_gemma":[0.90780884,0.08605665,0.0019622897,0.000008321669,0.00008046643,0.00019387463,0.0037860032,0.00006663152,0.00003691739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964912,0.0005646081,0.0010704522,0.0008151621,0.0006926578,0.00036593058],"domain_scores_gemma":[0.9985247,0.00021494146,0.00041787475,0.00033671613,0.00030094,0.00020479987],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011505092,0.00045138272,0.0009143816,0.00044071805,0.00028054888,0.00006733494,0.00015144817,0.00050845393,0.00002564152],"category_scores_gemma":[0.00014044404,0.00047472605,0.00026817565,0.00038987194,0.00023616668,0.000029209505,0.00013645114,0.0003367323,8.7663966e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001454005,0.00069749966,0.0003425008,0.008301723,0.0011873799,0.00007432405,0.0003606039,0.0010298542,0.58864444,0.00059046404,0.00005844514,0.39856738],"study_design_scores_gemma":[0.00782415,0.0057639466,0.015552577,0.002527065,0.004203922,0.0013407746,0.0024107439,0.0054461714,0.93266517,0.0055631297,0.013610022,0.0030923341],"about_ca_topic_score_codex":0.00017994372,"about_ca_topic_score_gemma":0.00014246751,"teacher_disagreement_score":0.44286174,"about_ca_system_score_codex":0.00009377287,"about_ca_system_score_gemma":0.00018851896,"threshold_uncertainty_score":0.99977046},"labels":[],"label_agreement":null},{"id":"W1994676607","doi":"10.3389/fgene.2014.00416","title":"From early lessons to new frontiers: the worm as a treasure trove of small RNA biology","year":2014,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Amgen (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; RNA silencing; Caenorhabditis elegans; RNA interference; Small RNA; RNA; Trans-acting siRNA; Genetics; RNA-induced silencing complex; Gene silencing; Computational biology; Gene","score_opus":0.021003171778193924,"score_gpt":0.3265189608674422,"score_spread":0.30551578908924826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994676607","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00059355533,0.83329606,0.16321607,0.00008683214,0.0017678995,0.000649733,0.00015039778,0.000010168246,0.00022930105],"genre_scores_gemma":[0.0002523814,0.9529061,0.04402639,0.00009303928,0.0011797664,0.00007063834,0.00028083025,0.00011472487,0.0010761755],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99761003,0.00019494782,0.0007569856,0.0007604444,0.00015200199,0.0005256055],"domain_scores_gemma":[0.9982227,0.000038692742,0.00027523213,0.0011789708,0.00005915827,0.00022524882],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024106452,0.0005844615,0.0014628185,0.00021970338,0.000040029685,0.0000326982,0.0010732729,0.00081719767,0.000008630806],"category_scores_gemma":[0.00014929641,0.00046772076,0.0005131592,0.00030497985,0.000111095316,0.0000013652741,0.00027933158,0.0003763341,0.000011809034],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003277754,0.000031628395,0.00017908636,0.00037851644,0.00042777933,0.0000021473388,0.0002430301,0.00020213303,0.000447921,0.000009429119,0.03285467,0.9651909],"study_design_scores_gemma":[0.00037789217,0.00033907944,0.000056874444,0.000727312,0.00045292932,0.000004257584,0.00008716014,0.000030843144,0.0012363247,0.000382195,0.9957906,0.00051450654],"about_ca_topic_score_codex":0.00033605626,"about_ca_topic_score_gemma":0.00013040152,"teacher_disagreement_score":0.9646764,"about_ca_system_score_codex":0.000052332,"about_ca_system_score_gemma":0.0003850087,"threshold_uncertainty_score":0.99977744},"labels":[],"label_agreement":null},{"id":"W1994702653","doi":"10.1016/j.ymthe.2004.08.016","title":"Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45negPFV hemogenic precursors","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Biology; Haematopoiesis; Embryonic stem cell; Transduction (biophysics); Transgene; Cell biology; Progenitor cell; Hemangioblast; Stem cell; CD34; Molecular biology; Retrovirus; Cell culture; Gene; Genetics","score_opus":0.0067546036456772535,"score_gpt":0.24475357049581783,"score_spread":0.23799896685014058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994702653","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9589714,0.0042331074,0.036168918,0.000038667913,0.00018173431,0.0002875751,0.000023306795,0.000032814318,0.00006248076],"genre_scores_gemma":[0.998576,0.00041118992,0.00052524026,0.00005150292,0.0000649767,0.000020812307,0.0001635697,0.000063333144,0.00012338163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873364,0.000059007256,0.0002986778,0.00043225082,0.00019184814,0.00028458674],"domain_scores_gemma":[0.99924946,0.0000036739455,0.0001026619,0.000508482,0.00005125059,0.00008450038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006252211,0.0002700747,0.0002600118,0.000057450463,0.00005895308,0.000018762674,0.00024301866,0.00020191952,0.00004347633],"category_scores_gemma":[0.0000014344254,0.0002754325,0.00025494862,0.00011556691,0.00006370151,0.0000038459093,0.000031071813,0.000119144584,0.000006977619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007438219,0.00014196453,0.000060987975,0.00002579671,0.00012416659,0.000005029185,0.00029318672,0.0026914156,0.99590033,0.000015100115,0.00001451559,0.00065314764],"study_design_scores_gemma":[0.0021519067,0.00045769406,0.00074680493,0.000023558636,0.00003811053,0.000004006703,0.00009360098,0.000018260402,0.99579805,0.00015090556,0.00022993078,0.0002871977],"about_ca_topic_score_codex":0.000049742677,"about_ca_topic_score_gemma":0.000009444327,"teacher_disagreement_score":0.0396046,"about_ca_system_score_codex":0.000022439954,"about_ca_system_score_gemma":0.00003747323,"threshold_uncertainty_score":0.9999698},"labels":[],"label_agreement":null},{"id":"W1994745775","doi":"10.1016/j.exphem.2013.05.116","title":"Regulation of mouse embryonic stem cell fate by ribosomal proteins","year":2013,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Cell fate determination; Embryonic stem cell; Genetics; Complementation; Ribosomal protein; Phenotype; Cellular differentiation; Stem cell; Cell biology; Gene; Computational biology; Transcription factor; RNA; Ribosome","score_opus":0.0049103083379982955,"score_gpt":0.2558631658591108,"score_spread":0.2509528575211125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994745775","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99087805,0.0060386267,0.001995652,0.000038243088,0.00007641888,0.00031406712,0.000007543597,0.000015032742,0.0006363714],"genre_scores_gemma":[0.99685115,0.000013276175,0.0006760908,0.000026018672,0.000025870373,0.00009394127,0.00006116126,0.000020695912,0.0022318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993171,0.000024708444,0.00018251762,0.0002168284,0.00006833978,0.00019046964],"domain_scores_gemma":[0.9996275,0.0000037155376,0.00006270328,0.00022271764,0.000028612165,0.000054809145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000025368254,0.00012362875,0.00014966584,0.000024427774,0.0000282361,0.0000057534867,0.0001063591,0.00012328877,0.00010475194],"category_scores_gemma":[0.0000019197832,0.00012460595,0.00005474565,0.000033679735,0.000054217162,0.0000040215245,0.00007399458,0.000041120107,0.000036519177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013721883,0.00009087279,0.00027490663,0.00002484804,0.000012234452,3.4505663e-7,0.000058349313,0.000032572098,0.99651134,0.00034145944,0.0025426669,0.0000966969],"study_design_scores_gemma":[0.00040475384,0.00023167186,0.00015262955,0.000004537042,0.0000027993149,0.000020297268,0.00022635423,0.00014526855,0.99761367,0.000008174104,0.0010645922,0.0001252372],"about_ca_topic_score_codex":0.000022094317,"about_ca_topic_score_gemma":0.0000014936594,"teacher_disagreement_score":0.0060253507,"about_ca_system_score_codex":0.000009667808,"about_ca_system_score_gemma":0.000012657016,"threshold_uncertainty_score":0.50812835},"labels":[],"label_agreement":null},{"id":"W1995031457","doi":"10.1371/journal.pgen.1002544","title":"Modelling Human Regulatory Variation in Mouse: Finding the Function in Genome-Wide Association Studies and Whole-Genome Sequencing","year":2012,"lang":"en","type":"review","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of Mental Health; Genome British Columbia; Child and Family Research Institute; Genome Canada; GlaxoSmithKline","keywords":"Biology; Genetics; Human genome; Bacterial artificial chromosome; Genome; Computational biology; Gene; Locus (genetics)","score_opus":0.06643518494094512,"score_gpt":0.3157211983243768,"score_spread":0.24928601338343165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995031457","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.056057237,0.9416282,0.0016178645,0.0000127901785,0.00012091981,0.0005111986,0.000018635747,0.000011180211,0.000021958684],"genre_scores_gemma":[0.04941564,0.949221,0.0002793126,0.000031252457,0.0004305598,0.000099559984,0.00021054754,0.000070630784,0.0002414686],"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983074,0.00015747124,0.00057045394,0.0004020797,0.0001940043,0.00036859882],"domain_scores_gemma":[0.9991773,0.00010298032,0.0002777398,0.00033453334,0.000060728853,0.000046727662],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006960485,0.0003243143,0.00055391283,0.00017557487,0.000106798696,0.000038562506,0.00015411251,0.00040956683,0.0000017272001],"category_scores_gemma":[0.00009421661,0.00028933215,0.00009649665,0.00017422829,0.00002436906,0.0000062070976,0.00014895831,0.0003160022,0.0000032826847],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031435906,0.00023741626,0.006565,0.028998768,0.0027809402,0.000010282721,0.007044128,0.6700134,0.23556384,0.00007927778,0.0000682459,0.048607238],"study_design_scores_gemma":[0.0021458494,0.0006194928,0.004564138,0.0071158432,0.0048484984,0.00002784155,0.0014262238,0.018625187,0.0049783136,0.00058487954,0.95042425,0.004639492],"about_ca_topic_score_codex":0.0000058569294,"about_ca_topic_score_gemma":0.00006251069,"teacher_disagreement_score":0.950356,"about_ca_system_score_codex":0.00042175947,"about_ca_system_score_gemma":0.00007217258,"threshold_uncertainty_score":0.9999559},"labels":[],"label_agreement":null},{"id":"W1995191891","doi":"10.1101/pdb.prot080358","title":"Genetic Manipulation of Autophagy in the <i>Drosophila</i> Ovary","year":2014,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Germline; Biology; Gene knockdown; Mutant; Autophagy; Somatic cell; Gene; Genetics; Drosophila (subgenus); RNA interference; Drosophila melanogaster; Germline mutation; Genetic screen; Genetic analysis; Mutation; Cell biology; RNA","score_opus":0.012631248878783037,"score_gpt":0.2912364863026034,"score_spread":0.2786052374238204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995191891","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9496313,0.00025753,0.027197119,0.00008297977,0.000074108626,0.021986108,0.000002778749,0.000023938677,0.00074415957],"genre_scores_gemma":[0.98797214,0.0000048578845,0.0017078933,0.00009898389,0.00016708484,0.010016446,8.324261e-7,0.000017354896,0.000014426076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992533,0.00005294524,0.00021896494,0.00019348673,0.000119170705,0.00016213086],"domain_scores_gemma":[0.9994651,0.0000145164095,0.00005697608,0.0004098763,0.000027128966,0.000026418482],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002816521,0.00010380594,0.00010889734,0.00003500712,0.00002696534,0.000015384283,0.0002330851,0.000074918265,0.0000037598459],"category_scores_gemma":[0.000050986655,0.00009023853,0.000050711275,0.000089271925,0.000025664573,0.0000021945884,0.000053327767,0.00007139478,0.000003130635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020459769,0.00004679204,0.007945813,0.00008727809,0.0000068420045,0.0000014576319,0.000021517031,0.0030111824,0.9862704,0.0021839568,0.000048718,0.0003555523],"study_design_scores_gemma":[0.00062482385,0.00021075588,0.35675412,0.0000618876,0.0000064849223,0.0000014658862,0.0000035482526,0.002079756,0.613283,0.00006006034,0.026756408,0.00015770333],"about_ca_topic_score_codex":0.000012188555,"about_ca_topic_score_gemma":0.0000063474304,"teacher_disagreement_score":0.37298745,"about_ca_system_score_codex":0.0000065057843,"about_ca_system_score_gemma":0.000018861272,"threshold_uncertainty_score":0.36798203},"labels":[],"label_agreement":null},{"id":"W1995875746","doi":"10.1016/j.ymeth.2010.12.023","title":"PhiC31 integrase facilitates genetic approaches combining multiple recombinases","year":2010,"lang":"en","type":"article","venue":"Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Recombinase; Integrase; Site-specific recombination; Genome engineering; Integrases; Computational biology; Homologous recombination; Cre-Lox recombination; Genome; Biology; FLP-FRT recombination; Recombineering; Gene targeting; Genetics; Plasmid; Gene; Transgene; Genome editing; Genetic recombination; Recombination; Genetically modified mouse","score_opus":0.041088814996471726,"score_gpt":0.36698701275147905,"score_spread":0.32589819775500734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995875746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7160895,0.0008496958,0.2808924,0.000048083355,0.00054968207,0.00013733156,0.000009514953,0.000037729442,0.0013860884],"genre_scores_gemma":[0.64886194,0.00003526086,0.35049203,0.000034410805,0.00010338788,0.000033061413,0.00003538133,0.00002238675,0.00038211315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989775,0.00012369541,0.00020236865,0.0003596807,0.00007075759,0.00026602813],"domain_scores_gemma":[0.9992731,0.000101815174,0.000037774415,0.0004413226,0.000037074384,0.00010886779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005012184,0.0001864962,0.00016577206,0.00005036725,0.000073930045,0.000028817756,0.00020996197,0.00015875959,0.00007163232],"category_scores_gemma":[0.0006638167,0.0001757995,0.00010404397,0.000084707266,0.00008415755,0.0000023815717,0.000111941954,0.00022730893,0.000009318606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016486534,0.000048358055,0.0039738794,0.000020445494,0.00003651064,0.0000016872572,0.000096386844,0.00025467254,0.89483756,0.00003769802,0.0003102797,0.10036605],"study_design_scores_gemma":[0.00050267414,0.00015734647,0.0061866827,0.000007329827,0.000025034793,0.000030543288,0.0002530373,0.003991079,0.94974154,0.00041885168,0.038371224,0.00031465472],"about_ca_topic_score_codex":0.000035005654,"about_ca_topic_score_gemma":0.000043447657,"teacher_disagreement_score":0.100051396,"about_ca_system_score_codex":0.0000037615175,"about_ca_system_score_gemma":0.000024189038,"threshold_uncertainty_score":0.71688956},"labels":[],"label_agreement":null},{"id":"W1996450064","doi":"10.1038/nmeth.1454","title":"Targeted gene deletions in C. elegans using transposon excision","year":2010,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Transposable element; Biology; Caenorhabditis elegans; Genetics; Gene; Insert (composites); Transposase; Genome; DNA; Sleeping Beauty transposon system; Gene knockout; Computational biology","score_opus":0.008930957968437984,"score_gpt":0.41237219860199525,"score_spread":0.4034412406335573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996450064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5492061,0.0013953735,0.4486808,0.00004590609,0.00045670583,0.00007440699,0.0000061085475,0.000010134248,0.0001244667],"genre_scores_gemma":[0.5914507,0.000037977683,0.40816414,0.0000644703,0.0001863916,0.000003954527,0.00003087213,0.000015619375,0.00004588673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992399,0.000076976765,0.00014854307,0.00025797833,0.00007608141,0.00020048287],"domain_scores_gemma":[0.9995756,0.00002742595,0.000021992026,0.00027277085,0.00004308164,0.00005909318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043457546,0.00012259332,0.000117378906,0.00007854637,0.000039924555,0.000010414633,0.00013221835,0.0005211279,0.000024330253],"category_scores_gemma":[0.00019564894,0.0001195183,0.00007208467,0.00017556145,0.00002197407,0.0000022538677,0.000024205252,0.0005643332,8.176938e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015209688,0.000018695517,0.0003881897,0.0000059579147,0.0000075990347,0.0000024027788,0.00003054711,0.0017421123,0.9887826,0.000033803783,0.000032849537,0.0089400215],"study_design_scores_gemma":[0.00026399497,0.00003091291,0.0039148317,0.000005274782,0.000011025909,0.000016688764,0.00001051003,0.0036917073,0.9645554,0.000086987304,0.027260631,0.00015202333],"about_ca_topic_score_codex":0.000014368007,"about_ca_topic_score_gemma":0.00010040308,"teacher_disagreement_score":0.042244576,"about_ca_system_score_codex":0.000007098994,"about_ca_system_score_gemma":0.00003201338,"threshold_uncertainty_score":0.4873815},"labels":[],"label_agreement":null},{"id":"W1996542147","doi":"10.1162/biot.2008.3.1.79","title":"Genetic = Heritable (Genetic ≠ DNA)","year":2008,"lang":"en","type":"article","venue":"Biological Theory","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Philosophy of biology; Biology; Evolutionary biology; Genetics; Computational biology; Epistemology; Philosophy","score_opus":0.01638870407921495,"score_gpt":0.2650916483934564,"score_spread":0.24870294431424145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996542147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9686969,0.0047496827,0.023151143,0.00002165294,0.0001735687,0.00012969434,0.0000073854085,0.00004638902,0.003023571],"genre_scores_gemma":[0.9924796,0.0011163558,0.004438283,0.00026749325,0.00039072116,0.000026818407,0.00001839289,0.000020281557,0.00124205],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989522,0.000092853996,0.00017713087,0.00036535301,0.000079115045,0.00033331622],"domain_scores_gemma":[0.99946076,0.00002550735,0.000029327628,0.00034008228,0.00003099113,0.00011335295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012671863,0.00017645396,0.00015264653,0.000022841128,0.00010719655,0.000007796403,0.00022622796,0.00019783094,0.00017274408],"category_scores_gemma":[0.00010977112,0.00014062965,0.00011136112,0.00007331819,0.00017407612,0.0000010927496,0.0001235694,0.0000776985,0.0000810157],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010968849,0.000089269975,0.015848694,0.000009473698,0.00005177982,0.00004834217,0.00003623487,0.00044952842,0.9745333,0.0005844323,0.0017395073,0.0064997324],"study_design_scores_gemma":[0.0010700322,0.0013306449,0.46345073,0.000015058784,0.00002563678,0.0006831879,0.0001091573,0.00009048288,0.3401123,0.00411471,0.18797392,0.0010241342],"about_ca_topic_score_codex":0.0000021452463,"about_ca_topic_score_gemma":9.1171705e-7,"teacher_disagreement_score":0.634421,"about_ca_system_score_codex":0.00000709355,"about_ca_system_score_gemma":0.000025017884,"threshold_uncertainty_score":0.57347107},"labels":[],"label_agreement":null},{"id":"W1996865001","doi":"10.1186/1471-2164-9-93","title":"Gene conversion in the rice genome","year":2008,"lang":"en","type":"article","venue":"BMC Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Beijing Municipal Science and Technology Commission; Chinese Academy of Sciences; National Natural Science Foundation of China; Medical Research Council; Sundhed og Sygdom, Det Frie Forskningsråd","keywords":"Gene conversion; Pseudogene; Biology; Gene; Genetics; Genome; Gene duplication; Genome evolution; Chromosome; Gene family; Concerted evolution; Gene cluster; Gene density","score_opus":0.01296395050384428,"score_gpt":0.2464122337869027,"score_spread":0.23344828328305842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996865001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902738,0.0012285013,0.0076835155,0.000031809737,0.000079226054,0.00010803108,0.000005219086,0.000004752551,0.00058517494],"genre_scores_gemma":[0.9964833,0.00056585064,0.002289556,0.00021857746,0.00017734595,0.000007153963,0.00004331427,0.000011623727,0.0002032598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951243,0.000021605521,0.00010333283,0.00015604372,0.000056577846,0.0001500127],"domain_scores_gemma":[0.9996811,0.000008346026,0.000018981431,0.00025114897,0.0000134304055,0.00002695091],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010631632,0.000079863494,0.0000615497,0.000022893932,0.000051927705,0.00000601693,0.00018562403,0.00006222141,0.00000553202],"category_scores_gemma":[0.000013353965,0.00006764179,0.00004402185,0.00005571868,0.000027554186,9.078926e-7,0.000052983596,0.000053605952,0.000022218046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019886505,0.000022849414,0.0047168336,0.000010438394,0.0000060805373,0.00000736925,0.00034610138,0.003891917,0.9905126,0.000006373044,0.00040098216,0.00005855797],"study_design_scores_gemma":[0.0011252691,0.00016915525,0.19270302,0.0000027597398,0.000015576657,0.00028631138,0.00048046772,0.00052525126,0.6807119,0.000025953716,0.1235462,0.00040808512],"about_ca_topic_score_codex":0.000014860188,"about_ca_topic_score_gemma":0.000022353852,"teacher_disagreement_score":0.30980065,"about_ca_system_score_codex":0.000013074249,"about_ca_system_score_gemma":0.00004213183,"threshold_uncertainty_score":0.27583522},"labels":[],"label_agreement":null},{"id":"W1997833227","doi":"10.1158/1538-7445.am10-2559","title":"Abstract 2559: Development of carboplatin, docetaxel and combined carboplatin/docetaxel resistant ovarian cancer cell lines","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; Sudbury Regional Hospital; University of Sudbury; Laurentian University","funders":"","keywords":"Carboplatin; Docetaxel; Ovarian cancer; Drug resistance; Chemotherapy; Clonogenic assay; Medicine; Pharmacology; Paclitaxel; IC50; Cancer research; Cell culture; Cancer; Oncology; Internal medicine; Biology; Cisplatin; Microbiology; Genetics","score_opus":0.02646286224492996,"score_gpt":0.37610229796491584,"score_spread":0.3496394357199859,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997833227","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922714,0.005131332,0.000076149445,0.00012860152,0.00024775567,0.00027395447,0.000050950755,0.00001077457,0.001809051],"genre_scores_gemma":[0.9962988,0.0009799489,0.0015098894,0.000017948692,0.00028263332,0.00012601983,0.00003044609,0.000037861668,0.0007164453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984137,0.000028885413,0.00033539138,0.00042305267,0.00035093317,0.00044807966],"domain_scores_gemma":[0.99899644,0.000037159716,0.0000721456,0.0003893297,0.00032217204,0.00018277117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005216084,0.00018679138,0.00021822508,0.000073962874,0.00014663672,0.000034184814,0.00024452104,0.00018998873,0.00014513903],"category_scores_gemma":[0.000076557546,0.00017652725,0.00004710514,0.00015080126,0.00015286254,0.0000055165633,0.00019107618,0.00035735324,0.0000018411331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014769693,0.00004296836,0.0012330959,0.0002136942,0.000050924118,0.0000031060993,0.00030183635,0.00009987252,0.99271286,0.00002725365,0.0005239227,0.004642785],"study_design_scores_gemma":[0.00083241286,0.00008072004,0.039301068,0.000052363746,0.000011327768,0.0000015530437,0.00013790482,0.0000814294,0.9470921,0.000018877743,0.012171115,0.00021908568],"about_ca_topic_score_codex":0.0013281872,"about_ca_topic_score_gemma":0.0059673158,"teacher_disagreement_score":0.045620702,"about_ca_system_score_codex":0.000035960333,"about_ca_system_score_gemma":0.000526923,"threshold_uncertainty_score":0.7198572},"labels":[],"label_agreement":null},{"id":"W1998019363","doi":"10.1371/journal.pone.0100068","title":"BRCA1 Haploinsufficiency Leads to Altered Expression of Genes Involved in Cellular Proliferation and Development","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Haploinsufficiency; Biology; Gene; Genetics; Gene expression profiling; Gene expression; Regulation of gene expression; Cancer research; Phenotype","score_opus":0.02085003899741599,"score_gpt":0.24370939320840077,"score_spread":0.22285935421098477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998019363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9826639,0.0004289453,0.016676318,0.000023190374,0.000013902055,0.00014941265,7.70071e-7,0.0000049106434,0.000038650054],"genre_scores_gemma":[0.9870747,0.000037820468,0.012723496,0.000029122979,0.000052293963,0.00002141651,0.000019150333,0.0000084069425,0.00003362648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949056,0.000015635325,0.00014567404,0.00016097,0.00008764951,0.00009953614],"domain_scores_gemma":[0.999782,0.0000036512397,0.000021973518,0.00011903179,0.000031901654,0.000041442454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009883953,0.000067456494,0.00009579038,0.000041918236,0.000017682218,0.0000056675317,0.000051529667,0.00004794636,0.0000022759755],"category_scores_gemma":[0.00003794731,0.000066939116,0.000008091536,0.00003699297,0.000009895937,0.0000015782246,0.00005259664,0.000025003945,0.0000015558322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014723194,0.00016324173,0.021801803,0.000066631204,0.0000048679344,8.43969e-8,0.0001580794,0.00031073773,0.97677064,0.0000034009695,0.00000713452,0.0006986565],"study_design_scores_gemma":[0.00022467576,0.00013251686,0.010031139,0.00006029858,0.0000036942297,1.2899442e-7,0.000016943883,0.0005576299,0.98866475,0.0000029218345,0.00022198826,0.00008332646],"about_ca_topic_score_codex":0.000002213743,"about_ca_topic_score_gemma":0.000028036411,"teacher_disagreement_score":0.0118940985,"about_ca_system_score_codex":0.000004655511,"about_ca_system_score_gemma":0.00001702518,"threshold_uncertainty_score":0.27296978},"labels":[],"label_agreement":null},{"id":"W1998403384","doi":"10.1007/s12268-014-0473-7","title":"Angestaubt, aber nicht eingerostet — der Bioreporter LacZ","year":2014,"lang":"de","type":"article","venue":"BIOspektrum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"lac operon; Operon; Bioreporter; Reporter gene; Biology; Beta-galactosidase; Escherichia coli; Computational biology; Genetics; Molecular biology; Gene; Gene expression","score_opus":0.00569484755852634,"score_gpt":0.2645566647138538,"score_spread":0.25886181715532747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998403384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84569687,0.08304621,0.032791298,0.004122524,0.012590171,0.0011137595,0.00034796138,0.00021826252,0.020072969],"genre_scores_gemma":[0.98991597,0.0008134007,0.0012735426,0.0009098572,0.0026880307,0.000015506066,0.00023407738,0.00010439226,0.0040452415],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99767166,0.00007190408,0.00047840402,0.0007899568,0.0002444847,0.0007435732],"domain_scores_gemma":[0.99843997,0.000021314905,0.00015434166,0.0010082194,0.00009613555,0.00028000274],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003326866,0.00046605692,0.00035240504,0.00007643656,0.00011423721,0.00009997122,0.00031693757,0.00050539424,0.00024096419],"category_scores_gemma":[0.00011954753,0.0004633507,0.00024924896,0.00014743162,0.00013231799,0.000005386954,0.00025699066,0.0002081869,0.00048124816],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011744036,0.0003032966,0.03323968,0.00032111796,0.0010087608,0.000058822618,0.00023617242,0.00017480314,0.8439316,0.0002850465,0.09697153,0.023351718],"study_design_scores_gemma":[0.00060894294,0.0003297709,0.009977464,0.000047419377,0.00019399791,0.00002896291,0.000023973465,0.00029281309,0.2634739,0.00003413085,0.72437817,0.000610461],"about_ca_topic_score_codex":0.00001936123,"about_ca_topic_score_gemma":0.000047949394,"teacher_disagreement_score":0.62740666,"about_ca_system_score_codex":0.000025888503,"about_ca_system_score_gemma":0.000067338224,"threshold_uncertainty_score":0.99978185},"labels":[],"label_agreement":null},{"id":"W1998416686","doi":"10.1007/s00248-013-0217-0","title":"CRISPRs of Enterococcus faecalis and E. hirae Isolates from Pig Feces Have Species-Specific Repeats But Share Some Common Spacer Sequences","year":2013,"lang":"en","type":"article","venue":"Microbial Ecology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Enterococcus hirae; Feces; Enterococcus faecalis; Enterococcus; Microbiology; Zoology; Genetics; Bacteria; Staphylococcus aureus; Antibiotics","score_opus":0.009107285983429502,"score_gpt":0.24587867862506677,"score_spread":0.23677139264163727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998416686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955198,0.0029678617,0.00017040691,0.00031943727,0.00032059863,0.00024271356,0.00022614998,0.000014624512,0.00021839107],"genre_scores_gemma":[0.9974373,0.0008627539,0.00041116017,0.00020682238,0.0002835307,0.000020112411,0.00023367598,0.00002273607,0.0005219148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888724,0.000052077117,0.00029566692,0.00041574155,0.000045891633,0.0003033688],"domain_scores_gemma":[0.99944526,0.000033761757,0.00009718315,0.00028384425,0.00005959909,0.00008034073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058633956,0.00020850512,0.00030840232,0.000054961398,0.000063376094,0.000038989703,0.00018144256,0.00023960583,0.00049191614],"category_scores_gemma":[0.000020846532,0.00020083507,0.00008502374,0.000032869273,0.00018330468,0.000009634799,0.00020292822,0.00011103769,0.000024029274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028302162,0.00003413859,0.01774065,0.000022071908,0.00005831781,0.0000040563464,0.00013704038,0.000050700044,0.9726041,0.0000069598113,0.008479308,0.00083435647],"study_design_scores_gemma":[0.00054153916,0.00029725354,0.0756727,0.000019813633,0.000021417063,0.0000201313,0.00032161624,0.000037975093,0.895773,0.000116732335,0.026918123,0.00025967788],"about_ca_topic_score_codex":0.000460388,"about_ca_topic_score_gemma":0.00095157797,"teacher_disagreement_score":0.07683108,"about_ca_system_score_codex":0.000017648323,"about_ca_system_score_gemma":0.000020088537,"threshold_uncertainty_score":0.81898165},"labels":[],"label_agreement":null},{"id":"W1998566517","doi":"10.1002/stem.1368","title":"Nicotinamide Overcomes Pluripotency Deficits and Reprogramming Barriers","year":2013,"lang":"en","type":"article","venue":"Stem Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Korea Research Institute of Bioscience and Biotechnology; Canadian Institutes of Health Research; Korea Research Council of Fundamental Science and Technology","keywords":"Reprogramming; NAD+ kinase; Biology; Induced pluripotent stem cell; Cell biology; Embryonic stem cell; Nicotinamide phosphoribosyltransferase; Stem cell; Intracellular; Somatic cell; Biochemistry; Cell; Enzyme","score_opus":0.004239214472321596,"score_gpt":0.23157208632773027,"score_spread":0.22733287185540868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998566517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99257207,0.00285303,0.0029702657,0.00004135129,0.00015630704,0.00018367656,0.0000028016264,0.000020949949,0.0011995673],"genre_scores_gemma":[0.99661946,0.00024906456,0.0013005033,0.00006169529,0.000070299015,0.000017943614,0.0000041656017,0.00001871955,0.0016581299],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931675,0.000013759902,0.00012522082,0.0002636928,0.000064131775,0.00021645614],"domain_scores_gemma":[0.99958146,0.0000071875106,0.000026140051,0.0002344429,0.000028606684,0.00012214699],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000067216526,0.00011464687,0.00009309529,0.000022002458,0.0000497673,0.000037587102,0.000078365636,0.00007769772,0.000032639324],"category_scores_gemma":[0.0000089663245,0.00010982813,0.000042167947,0.00004003168,0.000030857198,0.000002987041,0.00007582428,0.000049912407,0.000022971393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000039203205,0.0000065567983,0.0024403478,0.000043492237,0.000022531049,0.0000016226713,0.000090912516,0.00012871088,0.9745797,0.000035727055,0.0009383449,0.021708125],"study_design_scores_gemma":[0.00027345362,0.00012011487,0.0020278546,0.00001779371,0.000012016632,0.000016290745,0.00045402604,0.00023698514,0.97057664,0.00005051179,0.02596682,0.00024747898],"about_ca_topic_score_codex":0.000034085522,"about_ca_topic_score_gemma":0.0000052574082,"teacher_disagreement_score":0.025028475,"about_ca_system_score_codex":0.0000049218243,"about_ca_system_score_gemma":0.000014573016,"threshold_uncertainty_score":0.4478661},"labels":[],"label_agreement":null},{"id":"W1998656941","doi":"10.1128/mcb.24.16.6947-6956.2004","title":"BRCA1 Can Modulate RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Levels","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Biology; RNA polymerase II; CTD; Phosphorylation; Cell biology; Cyclin-dependent kinase; Molecular biology; Polymerase; Gene expression; Cell cycle; Gene; Genetics; Promoter","score_opus":0.005057648742720821,"score_gpt":0.2532380417817222,"score_spread":0.24818039303900138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998656941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9055119,0.004758759,0.088802256,0.0002761309,0.00016459248,0.00015555749,0.000029503857,0.000020471825,0.00028082923],"genre_scores_gemma":[0.9977055,0.000076816716,0.001381547,0.00030166205,0.00013048349,0.000016952463,0.00022867814,0.00003503978,0.00012328714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987615,0.000047551664,0.00022603724,0.0004998975,0.00007957938,0.00038548184],"domain_scores_gemma":[0.9994163,0.0000030728884,0.000053550495,0.00034303154,0.000036048412,0.00014801447],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001203705,0.00025577002,0.00020217015,0.000063680985,0.00014396844,0.000017777495,0.00014093387,0.00025922677,0.00001384441],"category_scores_gemma":[0.00001494414,0.00025993865,0.00010666748,0.00008367944,0.000115817194,0.0000024001588,0.00015328749,0.000117004565,0.000003104632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000214155,0.000033162993,0.00026202016,0.000011726215,0.00005445603,0.000050665665,0.00008527776,0.0005364947,0.99540514,0.0010006895,0.000008525201,0.0025304495],"study_design_scores_gemma":[0.0010079283,0.00034589143,0.00048663095,0.00000987429,0.00002920625,0.00007684376,0.000033752724,0.000059234666,0.99317056,0.0013421319,0.0031033012,0.0003346727],"about_ca_topic_score_codex":0.00010005748,"about_ca_topic_score_gemma":0.000036524358,"teacher_disagreement_score":0.09219363,"about_ca_system_score_codex":0.000019157127,"about_ca_system_score_gemma":0.000058199937,"threshold_uncertainty_score":0.9999853},"labels":[],"label_agreement":null},{"id":"W1998974421","doi":"10.1177/0270467604263120","title":"Microsystems and Nanoscience for Biomedical Applications: A View to the Future","year":2004,"lang":"en","type":"article","venue":"Bulletin of Science Technology & Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Saskatchewan; University of Alberta","funders":"","keywords":"Microsystem; Emerging technologies; Engineering ethics; Quality (philosophy); Ethical issues; Engineering; Nanotechnology; Management science; Computer science; Risk analysis (engineering); Business; Artificial intelligence","score_opus":0.0034531180429230304,"score_gpt":0.27185617431330605,"score_spread":0.268403056270383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998974421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5602647,0.015702039,0.35291743,0.06885118,0.00034235968,0.0017410936,0.00003637775,0.00007067376,0.000074110765],"genre_scores_gemma":[0.95276344,0.0006393857,0.045511696,0.00064488605,0.00012207052,0.00025393933,0.0000023176644,0.000006577776,0.000055714056],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992409,0.0000024114656,0.00012479592,0.00031112108,0.00011190115,0.00020892036],"domain_scores_gemma":[0.9995422,0.0000063941648,0.000036407106,0.00027805052,0.00008658885,0.00005036161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043182634,0.0000727711,0.000082446706,0.000041633768,0.00025433197,0.000012769313,0.00048685056,0.00011340297,0.0000013185307],"category_scores_gemma":[0.000049524817,0.000052801155,0.000045095716,0.00054270367,0.0016125129,9.2664396e-7,0.00018566416,0.00005421108,0.0000024475592],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000019912916,0.000020709515,0.00004047259,0.000028343557,0.0000045988827,4.4893333e-8,0.00013807196,0.000035038793,0.9889119,0.001488066,0.0028366076,0.0064941235],"study_design_scores_gemma":[0.0001708719,0.00013380371,0.00009133195,0.00001474937,0.000004477457,0.000019740371,0.0013201208,0.000009527803,0.22492276,0.00016770505,0.77307427,0.00007062904],"about_ca_topic_score_codex":0.000004303783,"about_ca_topic_score_gemma":0.0000029540038,"teacher_disagreement_score":0.7702377,"about_ca_system_score_codex":0.000012953055,"about_ca_system_score_gemma":0.000086028274,"threshold_uncertainty_score":0.5941371},"labels":[],"label_agreement":null},{"id":"W1999058501","doi":"10.1016/j.dnarep.2011.09.002","title":"PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells","year":2011,"lang":"en","type":"article","venue":"DNA repair","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute of Environmental Health Sciences; National Institute on Aging; University of California, San Francisco","keywords":"Telomere; Telomerase; Biology; Embryonic stem cell; Chromosome; Cell biology; Rad50; Genetics; Molecular biology; DNA repair; DNA; DNA-binding protein; Gene","score_opus":0.024500373263300144,"score_gpt":0.2818634283755712,"score_spread":0.2573630551122711,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999058501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978112,0.0005303243,0.0005705716,0.000042662574,0.0003809218,0.0003724774,0.00007295485,0.000097853146,0.00012104],"genre_scores_gemma":[0.9962069,0.00037918414,0.0021136638,0.00005601904,0.0002753208,0.000032694657,0.00009698015,0.000048778013,0.0007904883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841225,0.00006216583,0.00038976403,0.000580703,0.00016061412,0.0003944751],"domain_scores_gemma":[0.99922544,0.000042044856,0.00010249425,0.0004739793,0.0000357973,0.00012025523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028752864,0.00027260956,0.00028884422,0.00006562698,0.00010677244,0.000032607113,0.00017198447,0.00022607512,0.0000926553],"category_scores_gemma":[0.000024812623,0.00019344261,0.0001370792,0.00013396486,0.00005684576,0.000012142379,0.00013505788,0.00016551549,0.000012818476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020590378,0.00009527557,0.0011841325,0.00010216716,0.000053487034,0.00008685228,0.0005731349,0.0004015672,0.99167335,0.0000024706778,0.00010890754,0.0036595967],"study_design_scores_gemma":[0.0027004855,0.00040074054,0.005917632,0.00015547549,0.000033652203,0.00002459598,0.00022079723,0.0022831748,0.9850377,0.0000043700825,0.0028457055,0.00037570778],"about_ca_topic_score_codex":0.0007257285,"about_ca_topic_score_gemma":0.0009841555,"teacher_disagreement_score":0.0066357083,"about_ca_system_score_codex":0.000033104163,"about_ca_system_score_gemma":0.00006404569,"threshold_uncertainty_score":0.78883606},"labels":[],"label_agreement":null},{"id":"W2000097894","doi":"10.1097/01.fpc.0000114752.08559.a0","title":"Pharmacogenetics and the regulation of gene transcription","year":2004,"lang":"en","type":"review","venue":"Pharmacogenetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"","keywords":"Pharmacy; Pharmacogenetics; Library science; Medicine; Biology; Family medicine; Genetics; Gene; Computer science; Genotype","score_opus":0.024612236048078672,"score_gpt":0.36238951315319784,"score_spread":0.3377772771051192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000097894","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003264567,0.9905036,0.007699718,0.000017069335,0.00037278002,0.00086621975,0.00010126281,0.00001268637,0.000100216675],"genre_scores_gemma":[0.004971819,0.9925068,0.0015006494,0.000033048655,0.0004354237,0.00007759666,0.00025318062,0.00008936421,0.00013209406],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982803,0.00014977962,0.00065929897,0.00042283733,0.00022039792,0.00026742753],"domain_scores_gemma":[0.99910027,0.000033683802,0.00026876474,0.00040603342,0.00008973969,0.00010151439],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003057031,0.00043355595,0.00074007595,0.000090560614,0.00007183189,0.000022430584,0.0003169803,0.0002613737,0.000020094254],"category_scores_gemma":[0.000022256008,0.0003309582,0.0004010232,0.00017318246,0.00026604906,0.0000019501647,0.000088821245,0.00019267858,0.000003824986],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010376742,0.00007057778,0.000004410852,0.01059477,0.00075891975,0.0000018189397,0.00013710777,0.0021491444,0.109164886,0.00010102097,0.0002062267,0.8767074],"study_design_scores_gemma":[0.002119844,0.000078251665,0.0000108716185,0.00081237074,0.002364727,0.00010631307,0.000007766852,0.00017756553,0.09002465,0.000055875,0.9037873,0.00045443326],"about_ca_topic_score_codex":0.00000504185,"about_ca_topic_score_gemma":0.0000013901016,"teacher_disagreement_score":0.9035811,"about_ca_system_score_codex":0.000019773755,"about_ca_system_score_gemma":0.00015573516,"threshold_uncertainty_score":0.9999142},"labels":[],"label_agreement":null},{"id":"W2000433120","doi":"10.1038/nmeth.2449","title":"Scaling up the systematic hunt for mammalian genetic interactions","year":2013,"lang":"en","type":"letter","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Scaling; Computational biology; Biology; Evolutionary biology; Genetics","score_opus":0.015302224368812779,"score_gpt":0.40295777733056715,"score_spread":0.38765555296175436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000433120","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041660847,0.022106275,0.8968541,0.069766775,0.007757265,0.0024956365,0.00006885851,0.000044980636,0.00048946845],"genre_scores_gemma":[0.005346383,0.0002869679,0.62309974,0.30822003,0.020975763,0.0024778505,0.000920996,0.00037624192,0.038296033],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982068,0.00036664325,0.00039714263,0.0004834273,0.00016385519,0.0003821321],"domain_scores_gemma":[0.99834627,0.00037867346,0.00017285824,0.00088398956,0.00017041076,0.000047808433],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005790176,0.00036072658,0.0004082417,0.00007867318,0.00013305659,0.00009818247,0.0005221256,0.001381967,0.000031728592],"category_scores_gemma":[0.0006889101,0.00024906461,0.0003750956,0.00008868383,0.00004147931,0.0000019013531,0.00011226541,0.0015982334,0.000011302871],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000074491104,0.0000067998,0.000002436311,0.0067215282,0.00030159965,0.000003806119,0.000067418696,0.0001804577,0.03535874,0.000014606056,0.9525906,0.0047445493],"study_design_scores_gemma":[0.0001533739,0.00004135752,0.00002961516,0.00046406742,0.00029478845,0.00008178001,0.000049741815,0.0007110175,0.040157925,0.000112817674,0.95754564,0.0003578563],"about_ca_topic_score_codex":0.000007962893,"about_ca_topic_score_gemma":0.000004350221,"teacher_disagreement_score":0.2737544,"about_ca_system_score_codex":0.000027586366,"about_ca_system_score_gemma":0.000044290722,"threshold_uncertainty_score":0.9999962},"labels":[],"label_agreement":null},{"id":"W2001319731","doi":"10.1073/pnas.1418845112","title":"Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Haploinsufficiency; Embryonic stem cell; Biology; Gene; Stem cell; Genetics; Ribosomal protein; Phenotype; Ribosome; RNA","score_opus":0.024943024392671917,"score_gpt":0.3084443255628251,"score_spread":0.28350130117015315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001319731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977508,0.0005594291,0.0002933299,0.0003026418,0.000026162055,0.00028413793,0.000039889514,0.000004487891,0.00073907874],"genre_scores_gemma":[0.9975055,0.000011504288,0.0021256462,0.00001121371,0.00013132415,0.000015499436,0.0000011003684,0.000005692117,0.0001925415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988511,0.000004311364,0.00025457251,0.00022918062,0.0005111866,0.00014961057],"domain_scores_gemma":[0.9993527,0.000013507962,0.00026458432,0.000013453977,0.00031319621,0.000042560176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000602852,0.00009554127,0.00012762069,0.00006289105,0.00007695537,0.000011073335,0.0005481468,0.00006672197,9.3112243e-7],"category_scores_gemma":[0.00007445327,0.00006761761,0.00008556909,0.00021479376,0.00032966526,0.00001577384,0.00014180319,0.000045501525,2.2480717e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003063948,0.000045899935,0.0008142163,0.00007227481,0.000009420238,2.2329218e-9,0.00004604913,0.0006220356,0.9931353,0.00496341,0.00011662614,0.00014413182],"study_design_scores_gemma":[0.0003660089,0.00018782767,0.0032844865,0.000031062602,0.00001246115,0.0000022536299,0.000079710924,0.0014065689,0.99274516,0.0014994837,0.0003004644,0.000084531464],"about_ca_topic_score_codex":0.0000053276162,"about_ca_topic_score_gemma":2.887029e-7,"teacher_disagreement_score":0.0034639263,"about_ca_system_score_codex":0.0000087040025,"about_ca_system_score_gemma":0.000054848177,"threshold_uncertainty_score":0.27573663},"labels":[],"label_agreement":null},{"id":"W2001916053","doi":"10.1016/j.cub.2015.01.065","title":"Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense","year":2015,"lang":"en","type":"article","venue":"Current Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":301,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"Natural Environment Research Council; Biotechnology and Biological Sciences Research Council; AXA Research Fund; European Commission; Sight Research UK; Leverhulme Trust","keywords":"CRISPR; Biology; Genome; Palindrome; Genetics; Defence mechanisms; Immune system; Computational biology; Evolutionary biology; Gene","score_opus":0.0309519072515461,"score_gpt":0.36674245661921195,"score_spread":0.33579054936766584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001916053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.962047,0.011678305,0.023102282,0.000011926479,0.0013221022,0.00013957496,0.000036865364,0.000013999017,0.0016479623],"genre_scores_gemma":[0.9992621,0.00014489301,0.00028785501,0.0000039968354,0.00016827852,0.000012880662,0.00009661151,0.0000066142948,0.000016775286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933225,0.00005307783,0.00014593398,0.00024481228,0.000044439807,0.00017950372],"domain_scores_gemma":[0.9995254,0.000015093003,0.000059894293,0.00017613683,0.00014791473,0.00007555687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100254685,0.000113647104,0.00013702054,0.00005094838,0.000023346722,0.0000027075664,0.00009398314,0.0001295073,0.000002893531],"category_scores_gemma":[0.00017101884,0.00010790571,0.000052628788,0.00009539872,0.00015979623,0.0000022106553,0.000063895706,0.00008229683,0.000007592567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010094681,0.00022641166,0.12230295,0.000044689918,0.00026586905,0.0000015635113,0.00060221326,0.0015417648,0.8495947,0.008311543,0.0030294158,0.0130693875],"study_design_scores_gemma":[0.005684963,0.0035657012,0.021034824,0.000046181245,0.000112246795,0.000025964764,0.00068307744,0.00018327383,0.8830374,0.0012817258,0.08368466,0.0006600096],"about_ca_topic_score_codex":0.0000135970995,"about_ca_topic_score_gemma":0.000020451178,"teacher_disagreement_score":0.10126813,"about_ca_system_score_codex":0.000028631765,"about_ca_system_score_gemma":0.00014909763,"threshold_uncertainty_score":0.44002673},"labels":[],"label_agreement":null},{"id":"W2002165983","doi":"10.1089/zeb.2012.0832","title":"Evaluating the Mutagenic Activity of Targeted Endonucleases Containing a <i>Sharkey</i> FokI Cleavage Domain Variant in Zebrafish","year":2013,"lang":"en","type":"article","venue":"Zebrafish","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"","keywords":"Transcription activator-like effector nuclease; Zinc finger nuclease; Nuclease; Biology; Genome editing; FokI; Mutagenesis; Genetics; DNA; Cell biology; Genome; Mutant; Gene","score_opus":0.014646928563269103,"score_gpt":0.30092265565258236,"score_spread":0.28627572708931326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002165983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99555737,0.00046617544,0.0014330881,0.00018634732,0.00013259382,0.0005055211,0.000021620062,0.00002265685,0.0016746493],"genre_scores_gemma":[0.99827904,0.000024266848,0.0010218701,0.00031140796,0.00013781014,0.00008751179,0.000027470796,0.000038808295,0.00007181454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985272,0.00016628715,0.0003331826,0.00037279414,0.0002060102,0.0003944743],"domain_scores_gemma":[0.99915123,0.00008717149,0.0001314068,0.00048353826,0.00006693526,0.00007969966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005335508,0.00020921172,0.00025149787,0.00005440876,0.00008039063,0.00004456337,0.00031553602,0.00013375672,0.00013153978],"category_scores_gemma":[0.0002900097,0.00017682901,0.00013278784,0.00018007014,0.00007748454,0.000013137004,0.00019311672,0.00018482018,0.000011226801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008512132,0.00007274915,0.00080894347,0.000029711344,0.000058646605,0.0000074865075,0.00025487214,0.00036388327,0.9917244,0.000040421553,0.0010224191,0.0055313907],"study_design_scores_gemma":[0.0023078995,0.0009310243,0.06984418,0.0000796663,0.00004754252,0.00005895331,0.0005882094,0.003551744,0.9194281,0.00031894603,0.0023392225,0.0005045108],"about_ca_topic_score_codex":0.0003015322,"about_ca_topic_score_gemma":0.00011673153,"teacher_disagreement_score":0.072296254,"about_ca_system_score_codex":0.000018372184,"about_ca_system_score_gemma":0.00006413968,"threshold_uncertainty_score":0.72108775},"labels":[],"label_agreement":null},{"id":"W2002534691","doi":"10.1038/cr.2012.124","title":"The double-edged sword of CRISPR-Cas systems","year":2012,"lang":"en","type":"article","venue":"Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Biology; SWORD; CRISPR; Cleave; Computational biology; Immunity; DNA; RNA; Genetics; Immune system; Gene; World Wide Web; Computer science","score_opus":0.055781557644721015,"score_gpt":0.42472142770302296,"score_spread":0.3689398700583019,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002534691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91284686,0.043706525,0.005978298,0.00010053265,0.00072103506,0.00046004908,0.00000494428,0.0000108814265,0.03617088],"genre_scores_gemma":[0.99342036,0.0007623743,0.00004550342,0.0000034110672,0.00036783845,0.000030590112,0.000007487534,0.00001630316,0.005346129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894965,0.0000778037,0.0001419783,0.00012892396,0.00025334014,0.000448335],"domain_scores_gemma":[0.9992294,0.00006109614,0.00002106853,0.00042389138,0.00015598162,0.000108567394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011678933,0.000071098795,0.00007616936,0.000036722333,0.00012998644,0.000026795371,0.0002587671,0.00008480653,0.000010010832],"category_scores_gemma":[0.00004938325,0.000051358424,0.00004675103,0.000121135745,0.000101019876,0.0000017229548,0.00015766123,0.0001510771,0.000031451713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008245106,0.000047427,0.0020323177,0.000085317275,0.000020402147,5.7659514e-7,0.00012860211,0.00014563848,0.9854514,0.00035686194,0.01029515,0.0013538636],"study_design_scores_gemma":[0.00024911438,0.00006941538,0.0012306268,0.000006556469,0.000003185521,0.0000028100073,0.00033149545,0.000066401946,0.8222825,0.000005259229,0.17569268,0.000059939623],"about_ca_topic_score_codex":0.000042256746,"about_ca_topic_score_gemma":0.000006748515,"teacher_disagreement_score":0.16539752,"about_ca_system_score_codex":0.000010813559,"about_ca_system_score_gemma":0.000040991126,"threshold_uncertainty_score":0.20943357},"labels":[],"label_agreement":null},{"id":"W2003082286","doi":"10.1371/journal.pone.0119372","title":"CRISPR MultiTargeter: A Web Tool to Find Common and Unique CRISPR Single Guide RNA Targets in a Set of Similar Sequences","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Genome Atlantic","keywords":"CRISPR; Cas9; Biology; Genome editing; Guide RNA; Subgenomic mRNA; Genetics; Computational biology; Gene; CRISPR interference; Genome; Genome engineering","score_opus":0.03865644930724763,"score_gpt":0.30017501692720183,"score_spread":0.2615185676199542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003082286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962113,0.0015188747,0.0011963479,0.00033447042,0.000030439614,0.00025443925,0.000054492746,0.000011533406,0.00038812862],"genre_scores_gemma":[0.983889,0.00013115085,0.015477188,0.00018528209,0.00006830176,0.000023718938,0.000036206842,0.000019266505,0.00016989578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990747,0.000041309344,0.00026283663,0.00025531638,0.00014831919,0.00021751852],"domain_scores_gemma":[0.99947983,0.000015034255,0.000041768075,0.00024874165,0.000094097544,0.000120505945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022228326,0.00014356214,0.00023378673,0.00007111394,0.000017093409,0.000013287271,0.00013387825,0.00011024752,0.000007048026],"category_scores_gemma":[0.00021996495,0.00014802182,0.000029913608,0.000091488684,0.000037043195,0.0000051814677,0.00012432605,0.00007630088,0.0000027392657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000486263,0.0001812386,0.0042573293,0.000069561946,0.00004576658,0.0000068550953,0.00036746002,0.00054724724,0.99312806,0.0000040807117,0.0010166101,0.00032717246],"study_design_scores_gemma":[0.00053601357,0.00051119184,0.0015451802,0.00008747344,0.000023897957,0.000003001976,0.0001543291,0.0011663284,0.9929249,0.000047548285,0.0027934106,0.00020671892],"about_ca_topic_score_codex":0.00011337671,"about_ca_topic_score_gemma":0.0002790404,"teacher_disagreement_score":0.01428084,"about_ca_system_score_codex":0.000019358211,"about_ca_system_score_gemma":0.000053191656,"threshold_uncertainty_score":0.60361546},"labels":[],"label_agreement":null},{"id":"W2003276023","doi":"10.1002/humu.21101","title":"Functional redundancy of exon 12 of<i>BRCA2</i>revealed by a comprehensive analysis of the c.6853A&gt;G (p.I2285V) variant","year":2009,"lang":"en","type":"article","venue":"Human Mutation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; Princess Margaret Cancer Centre; University of Toronto; Jewish General Hospital; McGill University Health Centre; McGill University","funders":"National Cancer Institute; National Institutes of Health; Canadian Breast Cancer Research Alliance; U.S. Department of Defense","keywords":"Biology; Exon; Missense mutation; Genetics; Allele; BRCA2 Protein; Molecular biology; Hum; Mutation; Gene; Germline mutation","score_opus":0.010614760515733396,"score_gpt":0.2785662987341385,"score_spread":0.2679515382184051,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003276023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784117,0.00051287917,0.020479554,0.000029335002,0.000049993403,0.00010591074,0.000034555007,0.0000033549256,0.00037273677],"genre_scores_gemma":[0.9992581,0.000017319768,0.00023446548,0.00003448456,0.00002971234,0.0000029558605,0.00024958278,0.0000052668524,0.00016813482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935174,0.00003373858,0.00026230016,0.00013917782,0.00013526011,0.00007775623],"domain_scores_gemma":[0.99947083,0.000010083505,0.00016154104,0.00021226403,0.00012609012,0.000019191146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006832947,0.000079108664,0.00016655172,0.0000666344,0.00003377318,0.0000030102933,0.00007830773,0.000057957528,0.000028735825],"category_scores_gemma":[0.000018536357,0.000068585105,0.00014779664,0.00018652646,0.000043109463,0.0000022667518,0.000017302495,0.000034776465,2.4139422e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026627635,0.00005751395,0.0007640662,0.000021063888,0.00023316086,2.976621e-7,0.00013385422,0.01182287,0.9855386,0.00021323758,0.0006064913,0.0005822038],"study_design_scores_gemma":[0.0005400705,0.00025974415,0.47156748,0.000021515498,0.00043714012,0.000004334364,0.00008347146,0.0010334883,0.52523124,0.00018699879,0.00052397087,0.0001105404],"about_ca_topic_score_codex":0.000018073739,"about_ca_topic_score_gemma":0.000019901416,"teacher_disagreement_score":0.4708034,"about_ca_system_score_codex":0.000006665116,"about_ca_system_score_gemma":0.000020078298,"threshold_uncertainty_score":0.27968195},"labels":[],"label_agreement":null},{"id":"W2003547657","doi":"10.1371/journal.pone.0111781","title":"Transgene Detection by Digital Droplet PCR","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Transgene; Digital polymerase chain reaction; Computational biology; Biology; Polymerase chain reaction; Genetics; Gene","score_opus":0.008560248104971505,"score_gpt":0.21502443183848197,"score_spread":0.20646418373351047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003547657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91778874,0.00025490436,0.08065426,0.00004805145,0.000028526798,0.00006271452,0.000015638967,0.000021346572,0.0011257965],"genre_scores_gemma":[0.9987339,0.000045108114,0.00031971416,0.00005157552,0.00018081213,0.000010192147,0.000075992684,0.000017074666,0.0005656799],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995481,0.000006895706,0.0000787801,0.00015652168,0.00008350283,0.0001262325],"domain_scores_gemma":[0.9997589,0.0000036436652,0.00001252053,0.00015409764,0.000020355159,0.000050498464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000035292695,0.000075998054,0.00007329572,0.000013078926,0.000026279964,0.000019479961,0.000061705585,0.00006470259,0.0000130838325],"category_scores_gemma":[0.000028710097,0.00008059639,0.000033005253,0.000030617917,0.0000137953075,0.0000018222981,0.000015280233,0.0000398778,0.000018539247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009967477,0.000110170455,0.00020976181,0.000015839352,0.000040424602,1.019196e-7,0.000008852609,0.000021127074,0.9928269,0.0000017582397,0.00014412167,0.0066109984],"study_design_scores_gemma":[0.00022756823,0.00019205041,0.00020209856,0.0000059062822,0.000018901623,0.0000013661505,0.0000046708697,0.00058825355,0.989818,0.000012193658,0.00881856,0.0001104461],"about_ca_topic_score_codex":0.0000022404708,"about_ca_topic_score_gemma":0.0000055943237,"teacher_disagreement_score":0.08094509,"about_ca_system_score_codex":0.0000036314839,"about_ca_system_score_gemma":0.0000032003595,"threshold_uncertainty_score":0.32866254},"labels":[],"label_agreement":null},{"id":"W2004064009","doi":"10.1080/07391102.2009.10507299","title":"The Central Region of BRCA1 Binds Preferentially to Supercoiled DNA","year":2009,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"DNA; HMG-box; DNA supercoil; Superhelix; Chromatin; Protein–DNA interaction; Molecular biology; DNA-binding protein; Biology; DNA binding site; Electrophoretic mobility shift assay; DNA repair; Chemistry; Cell biology; DNA replication; Transcription factor; Biochemistry; Promoter; Gene; Gene expression","score_opus":0.0028254340491323886,"score_gpt":0.24315073657724415,"score_spread":0.24032530252811177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004064009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9218962,0.0009349762,0.0765071,0.00034952335,0.00017496377,0.000066076325,0.000008197087,0.0000016948543,0.0000612285],"genre_scores_gemma":[0.9982528,0.0003559851,0.0011140944,0.000105223546,0.00012595701,1.751446e-7,0.000010617831,0.0000086260425,0.000026540876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930334,0.000023280407,0.0002624028,0.00010806748,0.0001341727,0.00016871406],"domain_scores_gemma":[0.99950564,0.000005416793,0.000099889585,0.00017344537,0.000111660236,0.000103964536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007114706,0.00011202542,0.0001413042,0.000051313764,0.00004767486,0.000027302325,0.0001657259,0.00009897505,0.0000012993113],"category_scores_gemma":[0.000038561764,0.000077781035,0.0000973261,0.000084217354,0.00003325524,0.0000032464554,0.0000326278,0.000081209146,4.9316096e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013428344,0.000013848654,0.0003707341,0.000009670944,0.00006549701,0.000011255906,0.00006921034,0.00039169058,0.9758366,0.00032747682,0.00014323111,0.022626512],"study_design_scores_gemma":[0.0013116396,0.0023239069,0.0489072,0.000067634246,0.00013980421,0.0008220311,0.00017056802,0.001131521,0.9388055,0.0009692253,0.0049970034,0.00035393002],"about_ca_topic_score_codex":0.0000021976466,"about_ca_topic_score_gemma":0.000024868146,"teacher_disagreement_score":0.076356545,"about_ca_system_score_codex":0.0000108495105,"about_ca_system_score_gemma":0.00004316957,"threshold_uncertainty_score":0.31718186},"labels":[],"label_agreement":null},{"id":"W2004439872","doi":"10.1126/scitranslmed.3010262","title":"Human Cells: Finally Open for Cancer Business","year":2014,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Insertional mutagenesis; Transposable element; Lentivirus; Mutagenesis; Cancer cell; Cancer; Biology; Computational biology; Cancer research; Genetics; Cell biology; Mutation; Gene; Genome; Virus","score_opus":0.023983515245018284,"score_gpt":0.38609253116070413,"score_spread":0.36210901591568584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004439872","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3760539,0.0009537154,0.6022432,0.0100235,0.0011332168,0.0008716762,0.000036615398,0.000021891314,0.008662283],"genre_scores_gemma":[0.9952733,0.000014917114,0.0033700385,0.00031631748,0.00046150226,0.00003987183,0.000030242167,0.000007275236,0.0004865457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999322,0.000005644354,0.000115468276,0.00023788752,0.00016680156,0.000152224],"domain_scores_gemma":[0.99960536,0.00001077882,0.000023108722,0.00013061558,0.00016822062,0.00006191276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045104296,0.00007036064,0.000081685626,0.00004108772,0.00015196,0.000016470818,0.0003530281,0.000022626284,0.00004806306],"category_scores_gemma":[0.000051619536,0.000057875557,0.000015547655,0.00017870874,0.00022436232,0.0000061085957,0.000025602863,0.00002420546,9.2561385e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010177238,0.000008420317,0.00024975554,0.000015324342,0.0000035789913,4.8888563e-8,0.000047994326,0.0032053809,0.98936224,0.0012260752,0.0006447967,0.005226217],"study_design_scores_gemma":[0.0035722344,0.00057474594,0.120385036,0.00015108442,0.000052279298,0.0000065061713,0.000067384935,0.0071875905,0.57713133,0.0035032018,0.2868648,0.00050382636],"about_ca_topic_score_codex":0.000050429033,"about_ca_topic_score_gemma":0.00010254065,"teacher_disagreement_score":0.6192194,"about_ca_system_score_codex":0.0000042764555,"about_ca_system_score_gemma":0.00009970064,"threshold_uncertainty_score":0.23600967},"labels":[],"label_agreement":null},{"id":"W2004472959","doi":"10.1038/nbt1205-1485","title":"Innovation and intellectual property rights in systems biology","year":2005,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Waterloo","funders":"","keywords":"Intellectual property; Property rights; Systems biology; Property (philosophy); Business; Biology; Knowledge management; Computational biology; Law and economics; Computer science; Political science; Sociology; Epistemology; Law","score_opus":0.004469437203629854,"score_gpt":0.2695374664410893,"score_spread":0.2650680292374594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004472959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872773,0.0064177043,0.0041876887,0.0010178204,0.00023081251,0.00019678535,0.000004723574,0.000047130998,0.0006200294],"genre_scores_gemma":[0.9982648,0.00020072845,0.00094487716,0.00011586637,0.00016506556,0.0000146357925,0.000034257166,0.000008042098,0.0002517647],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999302,0.000017389943,0.00016983441,0.00029458784,0.00003153459,0.00018460653],"domain_scores_gemma":[0.9997129,0.000009223989,0.0000286441,0.00019557105,0.000037497408,0.000016151696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010969721,0.00011341238,0.0001187305,0.00023675189,0.000027314687,0.00000733734,0.00011521349,0.0011647051,0.000004505105],"category_scores_gemma":[0.00015047344,0.000081729224,0.000012556784,0.0002762228,0.00008357132,0.0000020188409,0.000085491796,0.00036846803,0.0000048987295],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029003017,0.00002753177,0.00047166998,0.000013311366,0.000016965007,0.0000015913038,0.000022778444,0.00008938463,0.96430624,0.01769987,0.0013547939,0.015966874],"study_design_scores_gemma":[0.0003259585,0.00015852116,0.00025090782,0.000009285395,0.000002771767,0.00005388634,0.000017379552,0.0006202484,0.44901124,0.00012508851,0.54928297,0.00014176553],"about_ca_topic_score_codex":0.000024619232,"about_ca_topic_score_gemma":0.00009576796,"teacher_disagreement_score":0.54792815,"about_ca_system_score_codex":0.000013538341,"about_ca_system_score_gemma":0.000015542371,"threshold_uncertainty_score":0.8983273},"labels":[],"label_agreement":null},{"id":"W2004548214","doi":"10.7326/0003-4819-148-3-200802050-00019","title":"Translation of Genetic Discoveries into Clinical Therapies","year":2008,"lang":"en","type":"letter","venue":"Annals of Internal Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Eye Institute","keywords":"Medicine; Translation (biology); Clinical trial; MEDLINE; Intensive care medicine; Bioinformatics; Computational biology; Pathology; Genetics; Gene","score_opus":0.04510914697278569,"score_gpt":0.39541924419046987,"score_spread":0.3503100972176842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004548214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45733884,0.11838909,0.05008967,0.3678466,0.0027638283,0.00058633427,0.00011037865,0.000024638202,0.0028506129],"genre_scores_gemma":[0.79438484,0.043333165,0.002128299,0.14858086,0.010010718,0.000015028972,0.0003488777,0.00009532314,0.0011029098],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985372,0.000059808506,0.00075151573,0.00025029498,0.0002454506,0.00015574503],"domain_scores_gemma":[0.9991439,0.00005939034,0.00027233487,0.00032720136,0.00015953778,0.000037619182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015984103,0.0002088742,0.00047914783,0.00008451797,0.000012839794,0.0000021026851,0.0002637833,0.00037535533,0.00004679257],"category_scores_gemma":[0.0001227494,0.00016335164,0.00022682417,0.00004522213,0.0004033268,0.0000020032146,0.000039026054,0.0003201863,0.0000011228802],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020761916,0.000040398558,0.0035591023,0.00037259227,0.00060618937,0.000041244453,0.00062373496,0.000043224005,0.04611002,0.0000026039593,0.9130652,0.03532807],"study_design_scores_gemma":[0.000571644,0.0020942246,0.00410078,0.00062454585,0.00006357465,0.000037931055,0.0000569318,0.000020734393,0.08868148,0.00010301217,0.90340775,0.00023738488],"about_ca_topic_score_codex":0.0001374173,"about_ca_topic_score_gemma":0.000013243225,"teacher_disagreement_score":0.33704597,"about_ca_system_score_codex":0.0000016484101,"about_ca_system_score_gemma":0.000037151163,"threshold_uncertainty_score":0.66612864},"labels":[],"label_agreement":null},{"id":"W2005122159","doi":"10.3389/fimmu.2013.00110","title":"A Novel Quantitative Fluorescent Reporter Assay for RAG Targets and RAG Activity","year":2013,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Liga Portuguesa Contra o Cancro; Terry Fox Foundation","keywords":"Recombinase; Biology; Recombination-activating gene; In silico; Reporter gene; Transfection; Flow cytometry; Computational biology; Gene; Molecular biology; Cell biology; Genome; Green fluorescent protein; Genetics; Gene expression","score_opus":0.008280396157555901,"score_gpt":0.2711574383152835,"score_spread":0.2628770421577276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005122159","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.48248896,0.0035602376,0.51254153,0.00020139341,0.0007155108,0.00039210054,0.000009963625,0.0000087556145,0.0000815487],"genre_scores_gemma":[0.92794734,0.0002880218,0.071096465,0.00006703441,0.000053038166,0.00018190489,0.000041301915,0.000022894572,0.00030197387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916595,0.000031597683,0.0001719383,0.00031402422,0.000039055143,0.00027745697],"domain_scores_gemma":[0.9996144,0.00001852375,0.00005960489,0.00022046159,0.000052814983,0.000034160374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016248015,0.00013775633,0.00019953703,0.00007180695,0.00003894397,0.00001321207,0.00009344848,0.00017708942,0.0000068395125],"category_scores_gemma":[0.00016037132,0.00013713341,0.00005185018,0.00004482738,0.00009786449,0.000005822026,0.000078116085,0.000088045126,0.0000013401698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013332705,0.00006328551,0.0039232206,0.000019653022,0.000121926525,0.0000016059669,0.00012625387,0.00005687494,0.9779152,0.00004990918,0.0069971737,0.010591563],"study_design_scores_gemma":[0.0035552967,0.000954389,0.15080413,0.000030202893,0.000038240138,0.00007761152,0.0008045861,0.006572913,0.79084295,0.00068911316,0.044962633,0.0006679275],"about_ca_topic_score_codex":0.00006369598,"about_ca_topic_score_gemma":0.000024313878,"teacher_disagreement_score":0.4454584,"about_ca_system_score_codex":0.000018943276,"about_ca_system_score_gemma":0.000026725416,"threshold_uncertainty_score":0.5592138},"labels":[],"label_agreement":null},{"id":"W2006137883","doi":"10.1038/nrmicro3240","title":"Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development","year":2014,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":674,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Council Canada; Sanofi","keywords":"Synthetic biology; Artemisinin; Metabolic engineering; Biology; Biochemical engineering; Drug discovery; Biotechnology; Systems biology; Computational biology; Malaria; Bioinformatics; Plasmodium falciparum; Engineering; Biochemistry; Immunology","score_opus":0.07851563570554373,"score_gpt":0.4105401902620697,"score_spread":0.332024554556526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006137883","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000019919671,0.96002895,0.037457418,0.000038808423,0.00035111693,0.0019629516,0.00012217702,0.000007802479,0.000010887876],"genre_scores_gemma":[0.0003074211,0.9932736,0.004652655,0.00022997559,0.00015981442,0.0005584287,0.00055358256,0.000070799055,0.00019372866],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969552,0.00038215058,0.0012991531,0.00079516444,0.000037835365,0.00053047406],"domain_scores_gemma":[0.99817276,0.00044600948,0.00043689573,0.0008017192,0.00007291472,0.000069674286],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009603355,0.0006102715,0.0021603785,0.000140777,0.00005117435,0.00001057571,0.00063296565,0.0017039722,0.00001070204],"category_scores_gemma":[0.00052598026,0.00038439396,0.00071326963,0.00016273677,0.0001901378,0.0000017938812,0.00022424279,0.00079679873,0.000011684114],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026362994,0.00006659679,0.000003132769,0.0111707365,0.00024783477,6.5347575e-7,0.000026541018,0.00026330788,0.009931594,0.000099089746,0.0025302332,0.9756339],"study_design_scores_gemma":[0.00022747429,0.000056026187,2.3614926e-7,0.0028890288,0.000385782,0.000107943386,8.960123e-7,0.00064821343,0.0011113291,0.0000061585097,0.9941714,0.00039552737],"about_ca_topic_score_codex":8.6148873e-7,"about_ca_topic_score_gemma":0.000016439748,"teacher_disagreement_score":0.99164116,"about_ca_system_score_codex":0.00004627538,"about_ca_system_score_gemma":0.00024851077,"threshold_uncertainty_score":0.9998608},"labels":[],"label_agreement":null},{"id":"W2006250096","doi":"10.1038/npre.2012.6965.1","title":"Quantitative Models for Efficient Cloning of Different Vectors with Various Clone sites","year":2012,"lang":"en","type":"preprint","venue":"Nature Precedings","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cloning (programming); clone (Java method); Restriction enzyme; Transformation (genetics); Ligation; Computational biology; Restriction digest; Biology; Restriction site; Molecular biology; Vector (molecular biology); Genetics; DNA; Computer science; Recombinant DNA; Gene","score_opus":0.012071258346012487,"score_gpt":0.30664294754288274,"score_spread":0.29457168919687027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006250096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8294789,0.0075642117,0.16147989,0.000034544282,0.00047293658,0.0006035156,0.00010282043,0.000023191526,0.00023995384],"genre_scores_gemma":[0.9816046,0.00013218888,0.017388547,0.000022130098,0.00025478494,0.000104303595,0.0003726806,0.000062551015,0.000058208298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986871,0.000017766972,0.0002531822,0.0005018331,0.00020133806,0.00033877208],"domain_scores_gemma":[0.99907523,0.00005495038,0.00020411919,0.00033520674,0.00023730783,0.00009320806],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016280533,0.00035615283,0.00038806742,0.00008271973,0.000045581473,0.000021990361,0.00025286243,0.0007924008,0.0000030858719],"category_scores_gemma":[0.000093228,0.00029060294,0.00017721583,0.00005847567,0.00005364604,0.0000020998093,0.0003277573,0.0005849858,2.48753e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052216806,0.00014827031,0.0006651842,0.0007739976,0.00043356037,5.020192e-7,0.0011274951,0.13609198,0.8583448,0.0013450587,0.00028735684,0.00025962034],"study_design_scores_gemma":[0.000740081,0.0006105956,0.0010084225,0.00032449453,0.00026954553,0.000007262705,0.000107760156,0.028447067,0.9671089,0.00044146532,0.0003180138,0.00061638776],"about_ca_topic_score_codex":0.000010211106,"about_ca_topic_score_gemma":0.000013728813,"teacher_disagreement_score":0.15212567,"about_ca_system_score_codex":0.000028063181,"about_ca_system_score_gemma":0.00004637935,"threshold_uncertainty_score":0.99995464},"labels":[],"label_agreement":null},{"id":"W2006733085","doi":"10.1016/j.molmed.2014.09.009","title":"Building high-resolution synthetic lethal networks: a ‘Google map’ of the cancer cell","year":2014,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Universities Space Research Association; Saskatchewan Cancer Agency","keywords":"Synthetic lethality; Context (archaeology); Computational biology; Cancer; Identification (biology); Biology; Gene; Cancer cell; Cancer research; Bioinformatics; Genetics; DNA repair","score_opus":0.012364781884340008,"score_gpt":0.3406413887285923,"score_spread":0.3282766068442523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006733085","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001170068,0.9677067,0.030717537,0.00007597684,0.0006925442,0.00019887154,0.000012483972,0.000008246099,0.0004706468],"genre_scores_gemma":[0.012895245,0.9848586,0.00082764664,0.00007984845,0.00059666525,0.000096510914,0.00011804376,0.00009034017,0.0004371004],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981413,0.00019112517,0.0005898995,0.0004984019,0.00023530574,0.00034397977],"domain_scores_gemma":[0.9987714,0.000028483699,0.00027240528,0.00082456425,0.00003377528,0.00006932645],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036295605,0.0003871549,0.0009529602,0.00012671055,0.000029714538,0.0000045820534,0.0005363888,0.00037434106,0.000071323026],"category_scores_gemma":[0.00005060089,0.00026685031,0.00031920348,0.0002949427,0.00014106743,0.0000011504562,0.00020488551,0.00029447133,0.0000010369059],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015493066,0.00007484906,0.000006701135,0.006098902,0.00021946804,0.00001954544,0.000037736885,0.015862124,0.021330936,0.00029409298,0.002916522,0.9531236],"study_design_scores_gemma":[0.00061442895,0.0001761201,0.000022037308,0.007947183,0.00074776995,0.00002639461,0.0000074657523,0.00059879303,0.004003273,0.000018586883,0.9854143,0.00042364383],"about_ca_topic_score_codex":0.00025246013,"about_ca_topic_score_gemma":0.00008412755,"teacher_disagreement_score":0.9824978,"about_ca_system_score_codex":0.000059398735,"about_ca_system_score_gemma":0.00005568071,"threshold_uncertainty_score":0.99997836},"labels":[],"label_agreement":null},{"id":"W2008177395","doi":"10.1038/nprot.2013.105","title":"Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli","year":2013,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Synthetic biology; Biology; Computational biology; Gene; Function (biology); Escherichia coli; Functional genomics; Plasmid; Gene expression; Regulation of gene expression; Metabolic engineering; Transfer RNA; Genetics; Genomics; RNA; Genome","score_opus":0.011080395181415641,"score_gpt":0.28463927002891637,"score_spread":0.27355887484750074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008177395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86277974,0.00032080524,0.093013614,0.00007985721,0.000029502631,0.043742273,0.0000040093423,0.000010441639,0.000019785233],"genre_scores_gemma":[0.9259978,0.0000053283534,0.044178985,0.00018644289,0.000041378433,0.029483937,0.0000027374242,0.00002067857,0.0000827176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929947,0.00005865011,0.0001679245,0.0002359837,0.000077544486,0.00016044923],"domain_scores_gemma":[0.9995245,0.000024993911,0.000041733067,0.00026416275,0.00006563015,0.00007903357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013760902,0.00012056766,0.00014881157,0.000044398435,0.000015765383,0.000020099984,0.00009946438,0.00027311887,0.0000074377417],"category_scores_gemma":[0.000108344444,0.00010677283,0.00002670732,0.00006188927,0.000022222488,0.0000036694876,0.00005534858,0.00014075739,0.0000015599319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010650959,0.000029956296,0.00092209503,0.000040510073,0.000007695829,8.52299e-7,0.000026596494,0.0022472306,0.9952217,0.0000059862828,0.00033139362,0.0010594868],"study_design_scores_gemma":[0.0006578438,0.00019462749,0.013544223,0.00009429735,0.0000038081628,0.0000023232503,0.000004649298,0.0004641715,0.9815586,0.000029289118,0.003319429,0.00012672863],"about_ca_topic_score_codex":0.0000071125783,"about_ca_topic_score_gemma":0.0000036838294,"teacher_disagreement_score":0.06321808,"about_ca_system_score_codex":0.0000071398417,"about_ca_system_score_gemma":0.000025739666,"threshold_uncertainty_score":0.43540698},"labels":[],"label_agreement":null},{"id":"W2008865600","doi":"10.1182/blood.v95.10.3242","title":"Locus control region activity by 5′HS3 requires a functional interaction with β-globin gene regulatory elements: expression of novel β/γ-globin hybrid transgenes","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Locus control region; Enhancer; Biology; Globin; Chromatin; Intron; Regulatory sequence; Transgene; Molecular biology; Gene; Promoter; Genetics; Gene expression","score_opus":0.007092588456811795,"score_gpt":0.23805446009911221,"score_spread":0.23096187164230042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008865600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88547224,0.000521924,0.11351234,0.000033350727,0.00005387255,0.00017458649,0.00005728178,0.000016324037,0.00015807188],"genre_scores_gemma":[0.99830633,0.00013873268,0.00090741157,0.000038016107,0.00014114536,0.00003323212,0.00010430699,0.00002391406,0.000306922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990801,0.000029305578,0.00020826362,0.00032908111,0.00016651735,0.00018673539],"domain_scores_gemma":[0.99953276,0.000008582279,0.000084182626,0.00025940905,0.000052211133,0.000062879226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007691487,0.00017295012,0.0001593962,0.000032124273,0.000049677048,0.000010359531,0.00008692965,0.00008227327,0.000049791925],"category_scores_gemma":[0.000006290309,0.00015671902,0.00007638456,0.000052327847,0.00003864427,0.000011147598,0.000013398161,0.000069234586,0.0000013087689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063856324,0.00048366343,0.00034126022,0.000019999121,0.00008269053,0.0000024357728,0.000014068879,0.0024493882,0.987652,0.0000013828919,0.00067304954,0.0076414933],"study_design_scores_gemma":[0.003865323,0.00033407134,0.0015226293,0.00004714507,0.000070742644,0.00009626356,0.000014568029,0.00027756163,0.99036384,0.0000019320578,0.0032241293,0.00018178918],"about_ca_topic_score_codex":0.000021561464,"about_ca_topic_score_gemma":0.000007860863,"teacher_disagreement_score":0.112834066,"about_ca_system_score_codex":0.0000113980095,"about_ca_system_score_gemma":0.00003079229,"threshold_uncertainty_score":0.6390816},"labels":[],"label_agreement":null},{"id":"W2009627515","doi":"10.1007/s10539-010-9217-3","title":"Gene sharing and genome evolution: networks in trees and trees in networks","year":2010,"lang":"en","type":"article","venue":"Biology & Philosophy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Inheritance (genetic algorithm); Phylogenetic tree; Biology; Tree of life (biology); Evolutionary biology; Genome; Tree (set theory); Horizontal gene transfer; Set (abstract data type); Phylogenetics; Common descent; Phylogenetic network; Philosophy of biology; Organism; Genetics; Gene; Computer science; Mathematics","score_opus":0.007189392116757604,"score_gpt":0.25519932263419115,"score_spread":0.24800993051743356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009627515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98623854,0.009993755,0.0030239266,0.00017024415,0.00017997713,0.00012143502,0.0000038695052,0.000010808095,0.0002574382],"genre_scores_gemma":[0.99794495,0.0008153999,0.00032527055,0.000095169984,0.00071232195,0.00002087729,0.000055302597,0.000015958469,0.000014722843],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990727,0.0000219478,0.0001929814,0.00041653975,0.00002368084,0.00027217306],"domain_scores_gemma":[0.9996626,0.000012044515,0.00003085398,0.0002214529,0.000012804625,0.000060259874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015512663,0.00016108599,0.00017568246,0.00008738868,0.00003797671,0.000011926971,0.000120256824,0.00031868587,0.000004736628],"category_scores_gemma":[0.000018840603,0.00016085019,0.000028523877,0.000082215905,0.00012834971,0.0000036007327,0.0001677087,0.00022421542,5.026921e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006345887,0.000037968806,0.36442274,0.00000744907,0.000026705904,0.000008209572,0.000037052483,0.008152836,0.6240791,0.0015218285,0.00000842143,0.001634205],"study_design_scores_gemma":[0.0014259678,0.00029957484,0.9710817,0.000020969763,0.000015643338,0.000086940716,0.000015107384,0.018515263,0.0025966854,0.0038917337,0.00154985,0.0005006173],"about_ca_topic_score_codex":0.00003752615,"about_ca_topic_score_gemma":0.0007204534,"teacher_disagreement_score":0.62148243,"about_ca_system_score_codex":0.000007125345,"about_ca_system_score_gemma":0.000009311714,"threshold_uncertainty_score":0.6559281},"labels":[],"label_agreement":null},{"id":"W2010473549","doi":"10.1371/journal.pgen.1004436","title":"Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2","year":2014,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Azrieli Foundation","keywords":"Biology; Telomere; Gene silencing; Gene; Genetics; Subtelomere; Position effect; Chromatin; Ectopic expression; Gene expression; Locus (genetics); Population","score_opus":0.012593337612471433,"score_gpt":0.25316976589452483,"score_spread":0.2405764282820534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010473549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99565846,0.0027944597,0.0009257077,0.000117983065,0.00006937471,0.00020014892,0.000029528135,0.000010176757,0.00019416514],"genre_scores_gemma":[0.9968499,0.0012362507,0.0012522738,0.00036406243,0.0001384019,0.000012182981,0.00003801092,0.00003302525,0.00007587211],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893665,0.000031161235,0.00022038132,0.0004125809,0.00016250949,0.00023669997],"domain_scores_gemma":[0.9995417,0.000013750259,0.0000547378,0.00025244753,0.00003844793,0.00009890704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000089108384,0.00020157415,0.00015717145,0.00008296697,0.00006235749,0.000033994882,0.00007503003,0.00015758956,0.00000851456],"category_scores_gemma":[0.000015885807,0.00021271886,0.00003077798,0.000059831968,0.000022311835,0.0000035824198,0.00009076429,0.00008880311,0.000004587665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024187932,0.0000655377,0.028137913,0.000094756506,0.000015394087,0.0000012327466,0.00025901815,0.0012867551,0.96177137,0.0000078020275,0.00006328379,0.008272772],"study_design_scores_gemma":[0.0005354399,0.00024768335,0.045647077,0.000038810576,0.000030603223,0.000007567427,0.000069392496,0.0082098795,0.94461966,0.000057749236,0.0002686856,0.00026742805],"about_ca_topic_score_codex":0.000027175482,"about_ca_topic_score_gemma":0.00005103828,"teacher_disagreement_score":0.017509164,"about_ca_system_score_codex":0.000020631956,"about_ca_system_score_gemma":0.000012215635,"threshold_uncertainty_score":0.86744237},"labels":[],"label_agreement":null},{"id":"W2010596106","doi":"10.1038/nature02107","title":"Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi","year":2003,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":447,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cystic Fibrosis Canada; Pew Charitable Trusts; National Institutes of Health; Cystic Fibrosis Foundation; National Science Foundation","keywords":"Caenorhabditis elegans; RNA interference; Transposable element; Gene silencing; Biology; Germline; Cell biology; Genetics; Mutant; Gene; RNA","score_opus":0.0022704242982508854,"score_gpt":0.25905115852726546,"score_spread":0.2567807342290146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010596106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975189,0.021715106,0.00081589434,0.00047217606,0.00033931434,0.00013239418,0.000024071775,0.000010103666,0.0013019501],"genre_scores_gemma":[0.99799293,0.0002482503,0.00021467212,0.00094178616,0.00015360757,0.000008562433,0.00008394031,0.000014613009,0.00034160874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993327,0.000036212492,0.00010607337,0.00020015209,0.00011504932,0.00020980599],"domain_scores_gemma":[0.9997203,0.000012710495,0.000017676872,0.000198523,0.000022668108,0.000028174125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013135959,0.0001208297,0.00008221852,0.000022054617,0.00003999349,0.000015862393,0.00016632913,0.0005193235,0.000011632684],"category_scores_gemma":[0.00005601142,0.0000920138,0.000057536952,0.00011350092,0.000016591759,0.0000022458528,0.0000071679124,0.00088946737,0.0000016360912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001257384,0.00003213249,0.00049763126,0.000018131754,0.00001423177,0.0000119395645,0.00026781682,0.0002561606,0.988484,0.0001281411,0.008719814,0.0015574232],"study_design_scores_gemma":[0.0004772262,0.000089755,0.002282979,0.000016217826,0.000012091967,0.000053867414,0.00019141787,0.00007328951,0.84737664,0.00003670505,0.14917298,0.0002168186],"about_ca_topic_score_codex":0.000012993495,"about_ca_topic_score_gemma":0.0001327718,"teacher_disagreement_score":0.14110735,"about_ca_system_score_codex":0.000009082665,"about_ca_system_score_gemma":0.000021511698,"threshold_uncertainty_score":0.40054986},"labels":[],"label_agreement":null},{"id":"W2011350548","doi":"10.1007/s10577-013-9383-7","title":"A multitasking Argonaute: exploring the many facets of C. elegans CSR-1","year":2013,"lang":"en","type":"review","venue":"Chromosome Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Argonaute; Biology; RasiRNA; Chromatin; RNA interference; Genetics; Piwi-interacting RNA; Caenorhabditis elegans; Gene silencing; Small RNA; RNA; Cell biology; Gene; Computational biology","score_opus":0.19246018283809538,"score_gpt":0.462953568864113,"score_spread":0.2704933860260176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011350548","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001541693,0.9962089,0.0002962799,0.000018927754,0.00023699104,0.00097019965,0.00003993684,0.000013593227,0.0006734656],"genre_scores_gemma":[0.0037186344,0.99324715,0.00020693381,0.0000033345755,0.00060310634,0.0007281128,0.00010984923,0.00009575231,0.0012871295],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99753153,0.0002544572,0.0004856836,0.00054408883,0.00050164195,0.0006826067],"domain_scores_gemma":[0.99836713,0.00015211159,0.00010260672,0.0010454206,0.00020405653,0.00012867445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086145895,0.00034129687,0.0007087138,0.00020153343,0.00015384646,0.000063738524,0.00094179536,0.00028611577,0.00006606066],"category_scores_gemma":[0.00025619037,0.0002363183,0.0003805119,0.00042284073,0.00020915466,0.0000054988286,0.0006426453,0.0007186024,0.00011781848],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000494298,0.00007203288,0.0000037811126,0.01342765,0.00038485753,0.000012274905,0.00015211114,0.0000415748,0.020514196,0.00013992745,0.0035686586,0.96167797],"study_design_scores_gemma":[0.0001171068,0.000100276884,0.000008476127,0.0022743964,0.000054914723,0.000034416338,0.00007819811,0.000021789785,0.011627443,0.000008879185,0.98541707,0.00025706034],"about_ca_topic_score_codex":0.000035644007,"about_ca_topic_score_gemma":0.000006072627,"teacher_disagreement_score":0.98184836,"about_ca_system_score_codex":0.000051610597,"about_ca_system_score_gemma":0.00025562674,"threshold_uncertainty_score":0.96367806},"labels":[],"label_agreement":null},{"id":"W2012708443","doi":"10.1073/pnas.1414399111","title":"Circular permutation of a synthetic eukaryotic chromosome with the telomerator","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Advanced Research Projects Agency; National Science Foundation","keywords":"Centromere; Telomere; Synthetic biology; Biology; Eukaryotic chromosome fine structure; Computational biology; ENCODE; Chromosome; DNA; Gene; Genetics; Saccharomyces cerevisiae; DNA replication; Chromosome segregation; Cell biology","score_opus":0.010823794374484393,"score_gpt":0.27732389189857426,"score_spread":0.2665000975240899,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012708443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99793154,0.00016228549,0.000082606035,0.00093075447,0.0000072222715,0.00009025211,0.000002843187,0.0000018926604,0.00079060445],"genre_scores_gemma":[0.9994056,0.000012427929,0.0004209642,0.00007630549,0.000047449346,0.0000056089502,1.5852659e-7,0.0000032886974,0.000028193575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992683,0.000004691765,0.00012983693,0.00012762092,0.000394601,0.00007498396],"domain_scores_gemma":[0.9996594,0.000023826991,0.00014597632,0.000010609988,0.0001461128,0.000014067458],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050471915,0.000056305333,0.00007467921,0.000036832385,0.00006757482,0.0000066786174,0.0003342953,0.000038654103,0.0000025424579],"category_scores_gemma":[0.0001796359,0.000030473908,0.00003930896,0.00022060727,0.00041192042,0.0000074935606,0.000046569945,0.000046099798,2.0653296e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005642383,0.000011073169,0.0018819787,0.000049975504,0.000012309011,7.406361e-10,0.00007106018,0.0012778353,0.99414915,0.0023180847,0.000057620757,0.00016528004],"study_design_scores_gemma":[0.00009901449,0.000101699974,0.040522445,0.00003771318,0.000014001845,0.000008453997,0.00010321602,0.0012837165,0.9565129,0.0010750467,0.00019256787,0.000049216032],"about_ca_topic_score_codex":0.0000010312291,"about_ca_topic_score_gemma":4.027307e-8,"teacher_disagreement_score":0.038640466,"about_ca_system_score_codex":0.000004026483,"about_ca_system_score_gemma":0.000018121378,"threshold_uncertainty_score":0.1517738},"labels":[],"label_agreement":null},{"id":"W2013853655","doi":"10.1371/journal.pone.0065267","title":"Zinc Finger Nuclease Mediated Knockout of ADP-Dependent Glucokinase in Cancer Cell Lines: Effects on Cell Survival and Mitochondrial Oxidative Metabolism","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Marsden Fund; Royal Society; Medical Research Council; University of Toronto; National Health and Medical Research Council; Royal Society Te Apārangi","keywords":"Biology; Hexokinase; Gene knockout; Gene silencing; Cell biology; Cell culture; Knockout mouse; Zinc finger nuclease; Glucokinase; Molecular biology; Gene knockdown; Glycolysis; Biochemistry; Genetics; Zinc finger; Gene; Metabolism; Transcription factor","score_opus":0.010096508933519729,"score_gpt":0.23982107382503384,"score_spread":0.2297245648915141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013853655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956958,0.0032311385,0.000055752225,0.000048214562,0.00014456712,0.0004021489,0.00003842749,0.000008938262,0.00037500457],"genre_scores_gemma":[0.9975743,0.0010034867,0.0006309821,0.00005602241,0.00028529903,0.00008775823,0.00004344916,0.000029704415,0.0002889489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905354,0.00005716005,0.00020088979,0.00030034073,0.00017627305,0.00021177286],"domain_scores_gemma":[0.99947387,0.00005659057,0.000066173954,0.00021985077,0.00007982679,0.00010370835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005516242,0.00017642563,0.00026407806,0.00004499997,0.000018785227,0.000012208305,0.00010321916,0.00013231974,0.00007092586],"category_scores_gemma":[0.000089899964,0.00016771983,0.000041633513,0.000060834343,0.000028025177,0.000005344198,0.00008154574,0.0001039846,0.000012544334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088157096,0.0005403504,0.00037374016,0.00019319999,0.00006070187,0.000002819348,0.00013504845,0.000085051855,0.99809015,0.0000020689913,0.00009769771,0.0003310206],"study_design_scores_gemma":[0.0016753178,0.00020834665,0.004103735,0.00007135747,0.00006925623,1.5542163e-7,0.000068659836,0.00025154682,0.9932397,0.0000061472238,0.00012206109,0.0001836959],"about_ca_topic_score_codex":0.00048784155,"about_ca_topic_score_gemma":0.00020828078,"teacher_disagreement_score":0.0048504234,"about_ca_system_score_codex":0.000013255037,"about_ca_system_score_gemma":0.000030264617,"threshold_uncertainty_score":0.68394166},"labels":[],"label_agreement":null},{"id":"W2014489344","doi":"10.1371/annotation/2c1c26ac-ee7e-417d-9852-4d2995ad102b","title":"Correction: Germline Stem Cell Gene PIWIL2 Mediates DNA Repair through Relaxation of Chromatin","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Zhengzhou University; Dalhousie University; China Scholarship Council; Yale University","keywords":"Scholarship; Library science; Family medicine; Medicine; China; Political science; Computer science; Law","score_opus":0.024149178429985978,"score_gpt":0.23371644983035472,"score_spread":0.20956727140036874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014489344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99298906,0.0012819209,0.0026698005,0.0000124417165,0.0001727721,0.00013369074,0.000008683914,0.000043522203,0.0026880847],"genre_scores_gemma":[0.9886969,0.0004324746,0.009312604,0.000025047868,0.00020273661,0.000017718472,0.000060582646,0.000021430002,0.001230525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993064,0.00002023983,0.00022683325,0.00019683214,0.00012305986,0.00012667433],"domain_scores_gemma":[0.99949646,0.000009815558,0.00009871755,0.0002780194,0.000080426435,0.000036574853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008256234,0.000103771,0.00014217263,0.000021791328,0.000026690228,0.0000027561657,0.000081911894,0.00010445988,0.000056927],"category_scores_gemma":[0.000027142542,0.00010594783,0.000063283165,0.0000689886,0.00002752842,0.0000036152387,0.00004343306,0.00005488832,0.000011639218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024747353,0.00034369543,0.0014591897,0.000088130466,0.0000827262,9.994401e-7,0.00034981364,0.000033878943,0.99680793,0.0000049052487,0.0006240497,0.00017992944],"study_design_scores_gemma":[0.00023433419,0.0002832895,0.004071314,0.00003697928,0.000062461615,0.0000026278879,0.00006811321,0.0006182947,0.99430454,0.0000144588685,0.0001854569,0.00011816018],"about_ca_topic_score_codex":0.000021897138,"about_ca_topic_score_gemma":0.000010188749,"teacher_disagreement_score":0.0066428035,"about_ca_system_score_codex":0.000007696201,"about_ca_system_score_gemma":0.000020301379,"threshold_uncertainty_score":0.43204272},"labels":[],"label_agreement":null},{"id":"W2014882682","doi":"10.1074/jbc.m609180200","title":"Tec Kinase Itk Forms Membrane Clusters Specifically in the Vicinity of Recruiting Receptors","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Receptor; TEC; Cell biology; Chemistry; Kinase; Biophysics; Membrane; Biology; Biochemistry; Physics; Astronomy","score_opus":0.017026250348973364,"score_gpt":0.2778010625493369,"score_spread":0.2607748122003635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014882682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99533564,0.00059516885,0.0006867586,0.00015761174,0.00006384266,0.00005913583,0.0000042991037,0.0000026882642,0.0030948694],"genre_scores_gemma":[0.99858904,0.00020520821,0.0006865334,0.00005647489,0.00038295132,0.0000019606032,0.000016766524,0.0000065298113,0.00005451861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897456,0.000037909347,0.00052178244,0.0001372738,0.00014218359,0.00018631613],"domain_scores_gemma":[0.99944055,0.00005490952,0.00022525046,0.00016151406,0.000073768046,0.00004403264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054826617,0.00012561349,0.00021295242,0.000020689073,0.000025436673,0.000010447032,0.00029988596,0.00019338111,0.00003752339],"category_scores_gemma":[0.00021622416,0.00007490863,0.00015984537,0.000105801424,0.00009088359,0.0000027996225,0.000049082646,0.0002405291,4.7735494e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000104285355,0.00009001406,0.0032061748,0.00003310619,0.000011646668,0.000014215687,0.000020411971,0.00036379212,0.9949648,0.000005179616,0.00032272993,0.000863693],"study_design_scores_gemma":[0.00045545658,0.00019242444,0.0050318786,0.000038109425,0.0000085403435,0.00011399253,0.00035521665,0.000014866977,0.9858642,0.0000622279,0.007751926,0.00011112138],"about_ca_topic_score_codex":0.0000052690016,"about_ca_topic_score_gemma":0.0000034937948,"teacher_disagreement_score":0.009100512,"about_ca_system_score_codex":0.000015804762,"about_ca_system_score_gemma":0.000027306778,"threshold_uncertainty_score":0.30546853},"labels":[],"label_agreement":null},{"id":"W2014917186","doi":"10.1111/j.1399-3054.2005.00461.x","title":"Progression of programmed cell death in tobacco BY‐2 cells is delineated by specific changes in de novo and salvage synthesis of purine nucleotides","year":2005,"lang":"en","type":"article","venue":"Physiologia Plantarum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"De novo synthesis; Nucleotide; Purine; Adenine phosphoribosyltransferase; Purine metabolism; Nucleotide salvage; Biochemistry; Programmed cell death; Adenosine; Chemistry; Hydrogen peroxide; Inosine; Biology; Enzyme; Apoptosis","score_opus":0.006319490359433112,"score_gpt":0.2545297613187653,"score_spread":0.2482102709593322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014917186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99664253,0.0028725215,0.00004317827,0.00005674686,0.000015707048,0.00018833503,0.00013546816,0.0000067333335,0.00003880804],"genre_scores_gemma":[0.9956731,0.0025942493,0.0015200664,0.000025345544,0.000034217974,0.000022603535,0.00010013001,0.0000135144355,0.000016765367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991936,0.000042944757,0.00020874647,0.00023978962,0.00006191021,0.00025297984],"domain_scores_gemma":[0.9996948,0.000032316777,0.00006879963,0.00014671242,0.00001588605,0.000041485015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014303654,0.00014124147,0.00021605205,0.00005010932,0.000012843446,0.0000044511744,0.000111796755,0.000110856556,0.000009608318],"category_scores_gemma":[0.000015544238,0.00012490203,0.000027121925,0.00006979318,0.00004098124,0.0000027727488,0.000064732274,0.00008762522,6.4887286e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000121266734,0.00017835134,0.01648636,0.000070827875,0.000008954022,0.0000017619295,0.00007768299,0.00014151055,0.9746837,2.2970275e-7,0.0010848758,0.0071444926],"study_design_scores_gemma":[0.00038002152,0.00019805759,0.0086885225,0.00005904189,0.000005210502,0.0000017056592,0.00007127218,0.00023451197,0.98867863,0.0000018709484,0.0015527563,0.00012839597],"about_ca_topic_score_codex":0.000051741255,"about_ca_topic_score_gemma":0.00007360582,"teacher_disagreement_score":0.013994946,"about_ca_system_score_codex":0.000010870906,"about_ca_system_score_gemma":0.000010390096,"threshold_uncertainty_score":0.5093357},"labels":[],"label_agreement":null},{"id":"W2016835853","doi":"10.1093/embo-reports/kvd059","title":"BRCA1 can stimulate gene transcription by a unique mechanism","year":2000,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Transcription (linguistics); Mechanism (biology); Gene; Genetics; Biology; Transcription factor; Cell biology; Computational biology","score_opus":0.0043818511704673555,"score_gpt":0.24726672851620626,"score_spread":0.2428848773457389,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016835853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98347694,0.0006613133,0.01371675,0.00009993992,0.00016711847,0.0001474018,0.000013007839,0.00003511312,0.0016823985],"genre_scores_gemma":[0.99387187,0.00023307286,0.0006585544,0.00017560918,0.00010911841,0.000016333928,0.00020514488,0.000026209556,0.004704076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991806,0.00001590063,0.0002085339,0.00030164424,0.00009609434,0.0001971933],"domain_scores_gemma":[0.9995424,0.0000013866401,0.000033315417,0.0003112836,0.000024044137,0.000087532695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010699574,0.00012937855,0.00010416485,0.000018072817,0.000043582786,0.000015145771,0.00005326165,0.00011772014,0.00017945985],"category_scores_gemma":[0.0000071561167,0.00013549985,0.00006841199,0.00004635691,0.000013700624,0.0000017069146,0.000010541996,0.00005924805,0.000004205275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009383616,0.00002173131,0.0000663146,0.0000064973397,0.000022879007,0.00006266822,0.000042165448,0.0013199301,0.99291795,0.000008884582,0.0018544338,0.0036671634],"study_design_scores_gemma":[0.0001586842,0.00008665247,0.00036595602,0.000006080383,0.000016068814,0.00032537687,0.0000059640993,0.00017583037,0.9291442,0.00025403575,0.0692758,0.00018535415],"about_ca_topic_score_codex":0.00007234738,"about_ca_topic_score_gemma":0.00003405239,"teacher_disagreement_score":0.06742136,"about_ca_system_score_codex":0.000010405182,"about_ca_system_score_gemma":0.000029037725,"threshold_uncertainty_score":0.55255234},"labels":[],"label_agreement":null},{"id":"W2016836437","doi":"10.1016/s0895-7061(01)02068-4","title":"Development and application of a biological peptide pump for the study of the in vivo actions of angiotensin peptides","year":2001,"lang":"en","type":"review","venue":"American Journal of Hypertension","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Angiotensin II; In vivo; Renin–angiotensin system; Medicine; Peptide; Computational biology; Internal medicine; Biochemistry; Biology; Receptor; Biotechnology; Blood pressure","score_opus":0.047395345855587315,"score_gpt":0.33378086523927686,"score_spread":0.28638551938368956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016836437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5804638,0.41723293,0.0016870034,0.000029128134,0.00004943862,0.0005282368,0.0000052872583,7.2424064e-7,0.0000034300795],"genre_scores_gemma":[0.52805144,0.4708042,0.0010719137,0.000008452391,0.0000366071,0.000011341329,0.0000017614452,0.000009523763,0.000004750868],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99909663,0.000058642367,0.0005515799,0.00011552449,0.00009607335,0.000081526974],"domain_scores_gemma":[0.9988914,0.000106378786,0.0006539329,0.00018156244,0.00014502236,0.000021668591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002462378,0.00012060069,0.0006103445,0.00006738624,0.000028058439,0.0000019316897,0.00016007521,0.000055854758,3.818753e-7],"category_scores_gemma":[0.000097804754,0.00006104202,0.00017381251,0.00018036463,0.00011616294,0.0000015257755,0.000062506486,0.00009208808,2.1569173e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070118505,0.0002755996,0.0005745776,0.00028539068,0.0003032624,0.000001459612,0.00020498765,0.00025670283,0.052858993,0.000002788722,0.000056481585,0.94510967],"study_design_scores_gemma":[0.0016573945,0.0045821536,0.013980957,0.0036289492,0.0016281455,0.0010222998,0.007887158,0.0001541518,0.03165136,0.000010529109,0.933262,0.0005348851],"about_ca_topic_score_codex":0.00003211482,"about_ca_topic_score_gemma":0.00003102834,"teacher_disagreement_score":0.9445748,"about_ca_system_score_codex":0.000009130878,"about_ca_system_score_gemma":0.00007238514,"threshold_uncertainty_score":0.24892214},"labels":[],"label_agreement":null},{"id":"W2017012269","doi":"10.1016/j.molmed.2005.03.008","title":"Genetic therapies for cardiovascular diseases","year":2005,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Clinical trial; Disease; Intensive care medicine; Myocardial ischemia; Bioinformatics; Ischemia; Pathology; Internal medicine; Biology","score_opus":0.021111025783557617,"score_gpt":0.3645370505922271,"score_spread":0.34342602480866946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017012269","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012780529,0.9765139,0.022442464,0.00004184033,0.0002595583,0.00044911823,0.00005397196,0.000022035743,0.00020430786],"genre_scores_gemma":[0.00016373028,0.9941567,0.002581763,0.00007606732,0.0012439257,0.00040473713,0.00078222854,0.00013688774,0.0004539145],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979438,0.000100084246,0.0005587085,0.0007140117,0.0002540462,0.00042931916],"domain_scores_gemma":[0.9987619,0.000026538972,0.00009866705,0.00094006537,0.000040867126,0.00013195562],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001951304,0.000552843,0.0015010436,0.00036974155,0.000032565164,0.000010554052,0.00038741354,0.00034691085,0.000049644994],"category_scores_gemma":[0.00008368331,0.00045241838,0.0013227857,0.00031652788,0.000107600565,0.000001292361,0.000083525214,0.00016929377,0.000003630163],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062418376,0.000029203895,0.0000026334124,0.0013796374,0.0007896257,0.000027410668,0.000019098332,0.00029047605,0.0001407578,0.000016417065,0.0009458979,0.9963526],"study_design_scores_gemma":[0.0007371365,0.00020830493,0.000033214445,0.001304292,0.0016732739,0.000044794324,0.000010431574,0.000015611502,0.0000330975,0.000016610435,0.99546856,0.00045465687],"about_ca_topic_score_codex":0.0000094701845,"about_ca_topic_score_gemma":0.00001039405,"teacher_disagreement_score":0.99589795,"about_ca_system_score_codex":0.000036190275,"about_ca_system_score_gemma":0.00006377349,"threshold_uncertainty_score":0.99979275},"labels":[],"label_agreement":null},{"id":"W2017151347","doi":"10.1139/g2012-049","title":"Homing endonucleases: DNA scissors on a mission","year":2012,"lang":"en","type":"review","venue":"Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Homing endonuclease; Biology; Homing (biology); Genome; Transcription activator-like effector nuclease; Genetics; Computational biology; Genome editing; ENCODE; Group I catalytic intron; Gene; DNA; Zinc finger nuclease; RNA splicing; RNA","score_opus":0.0314620489103715,"score_gpt":0.34060878024250524,"score_spread":0.3091467313321337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017151347","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019178136,0.997195,0.00020362086,0.000005100718,0.00031897734,0.0002963998,0.000041567506,0.000019860583,0.0017276758],"genre_scores_gemma":[0.0006207287,0.9960811,0.00024319088,0.000033491942,0.0013767446,0.00002241948,0.00031605898,0.00008839823,0.0012178766],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987973,0.000041582356,0.0002688317,0.00040142445,0.00011616444,0.00037472424],"domain_scores_gemma":[0.9991802,0.00001317753,0.00009622501,0.0005194152,0.000016241693,0.00017474954],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001314295,0.00034937827,0.00052026624,0.00009515607,0.00006349204,0.000022881355,0.00026450114,0.00031239534,0.00010695405],"category_scores_gemma":[0.00002857561,0.0002990408,0.00035429763,0.000088770576,0.000021554544,0.0000011081678,0.00013887374,0.00015700981,0.00027471798],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000072523794,0.000032840675,4.0753517e-7,0.0028821605,0.00011820194,0.0000066914204,0.000026260886,0.000025186197,0.00875763,0.000011307382,0.00020118743,0.9879309],"study_design_scores_gemma":[0.000088149325,0.00008447712,0.000004916205,0.00070195517,0.00019992988,0.000036332127,0.000005927178,5.8433625e-7,0.00045377045,0.0000012929634,0.99808025,0.00034241902],"about_ca_topic_score_codex":0.0000015242119,"about_ca_topic_score_gemma":5.495077e-7,"teacher_disagreement_score":0.9978791,"about_ca_system_score_codex":0.000030068675,"about_ca_system_score_gemma":0.00006446732,"threshold_uncertainty_score":0.9999462},"labels":[],"label_agreement":null},{"id":"W2017293108","doi":"10.1016/j.tplants.2004.12.008","title":"Whirly transcription factors: defense gene regulation and beyond","year":2005,"lang":"en","type":"review","venue":"Trends in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Biology; Transcription factor; Gene; Genetics; Transcription (linguistics); Regulation of gene expression; Computational biology; Cell biology; Evolutionary biology","score_opus":0.030005580357039534,"score_gpt":0.33645070548121875,"score_spread":0.3064451251241792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017293108","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0032600993,0.99525845,0.00042765046,0.000005892676,0.00017470162,0.00009436971,0.00011461535,0.000010094629,0.0006541286],"genre_scores_gemma":[0.017726894,0.98072594,0.00062846707,0.000007631415,0.00011600286,0.000009714976,0.00050864386,0.000014261226,0.0002624286],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988877,0.00002056067,0.00024188195,0.0004575776,0.00015411795,0.00023812309],"domain_scores_gemma":[0.9996146,0.000008429944,0.00006182249,0.00022824857,0.000013796114,0.000073104704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022785556,0.0002080701,0.0002987106,0.00030732845,0.00005679217,0.000037882044,0.00018843827,0.00016258429,0.000010008055],"category_scores_gemma":[0.000014578985,0.00017725966,0.00007202993,0.00035395255,0.000114849834,0.0000075210155,0.000041586434,0.00010187588,0.0000015355163],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034802038,0.000014386323,0.000020206813,0.00020242625,0.00000741905,0.0000019677389,0.00008919314,0.00006769237,0.009433124,0.00004375089,0.00010203314,0.9900143],"study_design_scores_gemma":[0.00020844411,0.00010225107,0.0011013142,0.0005129421,0.00009245289,0.00014061245,0.000020309706,0.00019011907,0.0033243669,0.000010802593,0.9937847,0.00051163713],"about_ca_topic_score_codex":0.0000067391866,"about_ca_topic_score_gemma":0.00006062906,"teacher_disagreement_score":0.99368274,"about_ca_system_score_codex":0.000028832002,"about_ca_system_score_gemma":0.00005814367,"threshold_uncertainty_score":0.7228439},"labels":[],"label_agreement":null},{"id":"W2017685660","doi":"10.1371/journal.pgen.1003312","title":"The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Biology; Population; Bacteriophage; Genetics; Phagemid; Plasmid; Gene; Escherichia coli","score_opus":0.004309908287911976,"score_gpt":0.22607902782540867,"score_spread":0.2217691195374967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017685660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99687666,0.0021034172,0.0006761995,0.00008274478,0.000027479135,0.00016253929,0.000015944996,0.0000057076754,0.00004933007],"genre_scores_gemma":[0.99753326,0.0009024752,0.0013347175,0.000014546462,0.000030614967,0.000012055898,0.000113801965,0.000013658258,0.000044878467],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995556,0.000023005918,0.000120798664,0.000116717994,0.00006866714,0.00011520561],"domain_scores_gemma":[0.9996338,0.000020763873,0.000042357377,0.00018933167,0.000068832436,0.000044933455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000040555897,0.00008880924,0.00007554118,0.000015169938,0.00007554073,0.00001797975,0.000053278007,0.0000616983,0.0000050303915],"category_scores_gemma":[0.000027390057,0.00006602861,0.000011887925,0.00003759915,0.00008136773,0.0000025595307,0.00007163056,0.00004735034,6.8170164e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046455898,0.000053712138,0.09640608,0.00007551637,0.00010919116,5.5879127e-7,0.000084049934,0.00028935994,0.8988634,0.0000561585,0.00013251255,0.0038830405],"study_design_scores_gemma":[0.00064636365,0.00048460104,0.79612345,0.000026643409,0.000065139306,0.000031038642,0.0002488449,0.03855374,0.16272739,0.00023772535,0.00057455705,0.00028052193],"about_ca_topic_score_codex":0.00002823936,"about_ca_topic_score_gemma":0.00008418164,"teacher_disagreement_score":0.73613596,"about_ca_system_score_codex":0.0000053829626,"about_ca_system_score_gemma":0.000011058714,"threshold_uncertainty_score":0.26925686},"labels":[],"label_agreement":null},{"id":"W2018083759","doi":"10.1016/j.plasmid.2011.02.005","title":"Light producing reporter plasmids for Escherichia coli K-12 that can be integrated into the chromosome","year":2011,"lang":"en","type":"article","venue":"Plasmid","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Concordia University","keywords":"Plasmid; Biology; Escherichia coli; Chromosome; Genetics; Circular bacterial chromosome; Microbiology; Molecular biology; DNA; Gene","score_opus":0.019123097445526545,"score_gpt":0.2579466014245927,"score_spread":0.23882350397906615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018083759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925412,0.00029213467,0.0039947806,0.0005708733,0.0005635399,0.00044911046,0.0000182247,0.000038056463,0.0015320597],"genre_scores_gemma":[0.99442977,0.000049104896,0.0034887735,0.00035150995,0.00023343558,0.00016531025,0.00009702517,0.000041592706,0.0011434783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989771,0.0000198505,0.00021012178,0.00039873025,0.0001033504,0.00029084823],"domain_scores_gemma":[0.999297,0.000014742816,0.00007557912,0.00046813808,0.0000659968,0.00007849757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020265153,0.00019754416,0.00014866158,0.000028879642,0.00011902508,0.000026662305,0.00022642112,0.00012923504,0.000037644382],"category_scores_gemma":[0.000115580726,0.00014373027,0.00009351246,0.000071000504,0.000044587516,0.0000036426713,0.00008350886,0.00010098177,0.0000028686845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009070175,0.000044339446,0.00156904,0.00004207888,0.00009063835,0.00000453346,0.0021580434,0.000062882114,0.98758614,0.00003466967,0.0076721013,0.00064482493],"study_design_scores_gemma":[0.0002629086,0.00017089109,0.0008938709,0.000014578483,0.000030494879,0.000014288477,0.00025219616,0.0002262395,0.86877084,0.000039571365,0.12912689,0.00019723762],"about_ca_topic_score_codex":0.00010769045,"about_ca_topic_score_gemma":0.00056809717,"teacher_disagreement_score":0.1214548,"about_ca_system_score_codex":0.000018279108,"about_ca_system_score_gemma":0.00007691369,"threshold_uncertainty_score":0.58611506},"labels":[],"label_agreement":null},{"id":"W2018404810","doi":"10.1016/j.cell.2014.03.005","title":"Remote Control of Gene Function by Local Translation","year":2014,"lang":"en","type":"review","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":315,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Wellcome Trust; Canadian Institutes of Health Research; Ministry of Science, ICT and Future Planning; Autism Speaks","keywords":"Biology; Translation (biology); Gene; Genetics; Function (biology); Computational biology; Evolutionary biology; Messenger RNA","score_opus":0.00906077590553972,"score_gpt":0.27887757670852154,"score_spread":0.2698168008029818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018404810","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000027845897,0.5439432,0.45551613,0.0000010446702,0.000089111294,0.00010339242,0.00001906703,0.0000030994217,0.00032213217],"genre_scores_gemma":[0.002498617,0.9959309,0.00042064587,0.000013506635,0.00018562273,0.0000046053597,0.0005832257,0.00003139082,0.0003314594],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993397,0.00003667833,0.00024897017,0.00020571175,0.000060629805,0.000108315086],"domain_scores_gemma":[0.9996094,0.000010728981,0.0000960719,0.0002239579,0.00002274761,0.00003707029],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008964569,0.00016045706,0.00040135268,0.00002501444,0.000011667155,0.0000036144272,0.00008336841,0.00027658488,0.000010929561],"category_scores_gemma":[0.000004294099,0.00014798294,0.0002130657,0.000036737165,0.000021180656,4.3294762e-7,0.000006941679,0.00007318546,0.000009476433],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007402547,0.000009617634,9.206014e-8,0.0028709685,0.000040450486,1.480976e-7,0.0000020025489,0.0001151516,0.02927857,5.4543625e-7,0.00088130985,0.9667937],"study_design_scores_gemma":[0.00024007804,0.00010704912,1.9068915e-7,0.00018398963,0.0002627522,0.0000028544575,0.0000010343473,0.00024326907,0.019520048,0.0000019481167,0.9792969,0.00013984412],"about_ca_topic_score_codex":0.0000034668528,"about_ca_topic_score_gemma":0.0000012002793,"teacher_disagreement_score":0.9784156,"about_ca_system_score_codex":0.0000056656595,"about_ca_system_score_gemma":0.000036612415,"threshold_uncertainty_score":0.6034569},"labels":[],"label_agreement":null},{"id":"W2021262282","doi":"10.1016/j.mrfmmm.2015.03.010","title":"Single-molecule PCR analysis of an unstable microsatellite for detecting mutations in sperm of mice exposed to chemical mutagens","year":2015,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina; Carleton University; Health Canada","funders":"","keywords":"Microsatellite; Sperm; Germline; Biology; Genetics; Locus (genetics); Molecular biology; Germline mutation; Mutation; Mutation frequency; Allele; Gene","score_opus":0.043115644424437764,"score_gpt":0.3534013917634057,"score_spread":0.3102857473389679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021262282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8291941,0.00026588576,0.16991013,0.000025421508,0.000023930259,0.00043541857,0.000112284215,0.0000047869453,0.000028043374],"genre_scores_gemma":[0.9683535,0.0000094121115,0.03121818,0.000027341724,0.0000099917515,0.000054413693,0.0002767111,0.000027769174,0.000022678705],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839795,0.00011391822,0.00045345433,0.00039786418,0.00033825266,0.0002985627],"domain_scores_gemma":[0.999037,0.00005199522,0.000109942455,0.00024928455,0.00036540919,0.00018634096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007435221,0.00015231539,0.0003154452,0.0005731776,0.00003858574,0.000019476198,0.00016955611,0.000113173446,0.000006116978],"category_scores_gemma":[0.00021899185,0.00017292007,0.00012939231,0.00077480765,0.00009281582,0.0000106760035,0.00011919255,0.00005745122,3.1305618e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021721434,0.00021402062,0.00006040173,0.000088144756,0.00018981943,0.00000720225,0.0007632535,0.00781518,0.98759407,0.00009398584,0.0000019288302,0.002954808],"study_design_scores_gemma":[0.00086825655,0.00093422027,0.00016067266,0.000023822142,0.00013453647,0.0000057241423,0.0033784665,0.0042628534,0.989836,0.00020411592,0.00003520515,0.0001561575],"about_ca_topic_score_codex":0.00016149075,"about_ca_topic_score_gemma":0.00013515678,"teacher_disagreement_score":0.1391594,"about_ca_system_score_codex":0.000039679708,"about_ca_system_score_gemma":0.0000779071,"threshold_uncertainty_score":0.7051476},"labels":[],"label_agreement":null},{"id":"W2021312520","doi":"10.1186/1753-6561-5-s7-p152","title":"Transgene copy number estimation and analysis of gene expression levels in Populusspp. transgenic lines","year":2011,"lang":"en","type":"article","venue":"BMC Proceedings","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biology; Gene; Transgene; Agrobacterium; Genome; Genetically modified crops; Transformation (genetics); Genetically modified organism; Genetics; Complementary DNA; Botany; Biotechnology","score_opus":0.025673525882471234,"score_gpt":0.30346532414711086,"score_spread":0.2777917982646396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021312520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9449283,0.00029582626,0.05441679,0.0000043072077,0.00002029369,0.00009563286,0.000011433306,0.000007938323,0.00021946045],"genre_scores_gemma":[0.9646792,0.000064547974,0.035138465,0.000008797183,0.000021627213,0.000014126328,0.000024509898,0.000012031495,0.000036701815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993492,0.000004299088,0.00021911242,0.00022528133,0.00007472851,0.00012737786],"domain_scores_gemma":[0.9997824,0.000003170632,0.000045896384,0.00007536506,0.000049102775,0.000044065382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011370494,0.00010797789,0.00017185378,0.00009502279,0.00001701678,0.00000606401,0.00007507002,0.00010089269,0.000027111635],"category_scores_gemma":[0.000020811485,0.00010356563,0.0000705091,0.00024051224,0.000025791423,0.0000064057895,0.000014260142,0.000036491452,5.3021137e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047417692,0.000030157476,0.12931453,0.000062733576,0.00004774066,1.3270062e-7,0.0006772597,0.00022232682,0.86904055,0.00001660923,0.000010509248,0.0005300198],"study_design_scores_gemma":[0.00029839147,0.000042041844,0.16100575,0.000015509937,0.000114068396,0.0000024442188,0.000074455515,0.0025293985,0.83576286,0.000027996744,0.00002063064,0.00010643402],"about_ca_topic_score_codex":0.000021398975,"about_ca_topic_score_gemma":0.000030250798,"teacher_disagreement_score":0.03327769,"about_ca_system_score_codex":0.0000039467836,"about_ca_system_score_gemma":0.000011653629,"threshold_uncertainty_score":0.42232838},"labels":[],"label_agreement":null},{"id":"W2021347112","doi":"10.2174/187221508786241729","title":"Recent Patents of Gene Sequences Relative to DNA Polymerases","year":2008,"lang":"en","type":"review","venue":"Recent Patents on DNA & Gene Sequences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"DNA polymerase; DNA polymerase II; DNA clamp; In vitro recombination; Biology; Primase; Circular bacterial chromosome; Polymerase; DNA polymerase mu; DNA replication; Genetics; DNA; Eukaryotic DNA replication; Molecular biology; Gene; Molecular cloning; Polymerase chain reaction; Reverse transcriptase; Complementary DNA","score_opus":0.054261880688194264,"score_gpt":0.348039510915637,"score_spread":0.29377763022744274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021347112","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017828029,0.978594,0.00019104648,0.000076239754,0.0010909851,0.001241159,0.0005028155,0.000042265558,0.00043344565],"genre_scores_gemma":[0.0018780587,0.9946011,0.0009860788,0.00014011738,0.00039075952,0.00017093879,0.0012694463,0.000118209704,0.0004453175],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954717,0.00031149012,0.0012983243,0.0013742889,0.00072791625,0.0008162429],"domain_scores_gemma":[0.99766785,0.00005507211,0.0006507327,0.00093710865,0.00028536937,0.00040384568],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020407684,0.0010022692,0.0015887747,0.00032751737,0.00016401314,0.000048079273,0.0008990258,0.0006185803,0.00011028473],"category_scores_gemma":[0.00019389285,0.0008318552,0.00059744896,0.00066088437,0.00018824886,0.000016424281,0.00022444931,0.00032173743,0.000090836824],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006353928,0.00022998045,0.00006173119,0.00087255077,0.0007508612,0.00006437089,0.00009409613,0.0002877511,0.053472083,0.0000069347116,0.0006224051,0.9434737],"study_design_scores_gemma":[0.0002860342,0.0008361697,0.000047876943,0.0023360346,0.00024963878,0.00010957052,0.000044480457,0.0000029267626,0.26072815,0.000011027472,0.73443055,0.0009175365],"about_ca_topic_score_codex":0.00006575937,"about_ca_topic_score_gemma":0.000017800507,"teacher_disagreement_score":0.94255614,"about_ca_system_score_codex":0.00015798981,"about_ca_system_score_gemma":0.00051116396,"threshold_uncertainty_score":0.99941325},"labels":[],"label_agreement":null},{"id":"W2022631158","doi":"10.1016/j.pep.2003.09.007","title":"Deletion of the GPI pre-anchor sequence in human p97—a general approach for generating the soluble form of GPI-linked proteins","year":2004,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Recombinant DNA; Transfection; Chinese hamster ovary cell; Cell culture; Biology; Cleavage (geology); Cell; Biochemistry; Baby hamster kidney cell; Secretion; Cell biology; Gene; Molecular biology; Genetics","score_opus":0.019018115539738333,"score_gpt":0.2989297966052469,"score_spread":0.27991168106550857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022631158","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85871184,0.000548617,0.13910581,0.000101875834,0.000023503278,0.0014560387,0.0000066832167,0.000004374599,0.000041292344],"genre_scores_gemma":[0.9774218,0.00003414588,0.021650253,0.000014141167,0.00007728487,0.0006172569,0.0000542607,0.000010763333,0.00012006996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992958,0.000037295955,0.00025352548,0.00019687698,0.00009942263,0.00011709014],"domain_scores_gemma":[0.99949473,0.0000038426097,0.00014397826,0.00027609855,0.000061087754,0.000020246705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027115588,0.00009043142,0.00009102827,0.000022695676,0.00011254556,0.00001121976,0.00015113805,0.00009655639,0.0000010629561],"category_scores_gemma":[0.00005071639,0.000058942904,0.0000466868,0.00006819185,0.000055217803,0.000006661901,0.000046471858,0.000068965295,3.3905717e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026551035,0.00004393115,0.00013465178,0.00009541263,0.00000389582,1.2523688e-8,0.00031686426,0.005159509,0.99141526,0.00047047174,0.00001106949,0.0023223546],"study_design_scores_gemma":[0.0004931235,0.000083786195,0.001193488,0.000060778646,0.000005211598,0.0000012029845,0.000057067384,0.003609329,0.993566,0.0005524689,0.00030288025,0.00007470789],"about_ca_topic_score_codex":0.00004655612,"about_ca_topic_score_gemma":0.000011860079,"teacher_disagreement_score":0.11871002,"about_ca_system_score_codex":0.000010369613,"about_ca_system_score_gemma":0.000033277618,"threshold_uncertainty_score":0.24036218},"labels":[],"label_agreement":null},{"id":"W2022687290","doi":"10.1093/nar/gkh952","title":"Preferential accessibility to specific genomic loci for the repair of double-strand breaks in human cells","year":2004,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Locus (genetics); Genetics; Human genome; Genome; Chromosome; Genome instability; Population; DNA; Gene; DNA damage","score_opus":0.04879562465519525,"score_gpt":0.3911039991498811,"score_spread":0.3423083744946858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022687290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916341,0.00039569926,0.0065533402,0.00007355733,0.0000647513,0.00077449984,0.000022098802,0.000008825503,0.00047318471],"genre_scores_gemma":[0.9985288,0.000086698565,0.00087835005,0.00001060138,0.00018996706,0.000063473286,0.000020723917,0.000022448088,0.0001989642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987737,0.00003621212,0.00024741373,0.0003663269,0.00021538608,0.00036095138],"domain_scores_gemma":[0.99920136,0.000025667085,0.000020962318,0.0005540274,0.00011981003,0.000078151796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007973537,0.00010393897,0.00013154259,0.00008076641,0.00010549696,0.00002814603,0.0004208494,0.00011959025,0.000041316474],"category_scores_gemma":[0.000022146212,0.000084602056,0.0001022464,0.00016599668,0.000116693685,0.0000029684327,0.00020646678,0.00017402411,0.000005286791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034945033,0.00007860464,0.00077142374,0.00005434586,0.000021038077,5.894179e-7,0.00017447355,0.002340939,0.9945528,0.00009247073,0.0005789987,0.0009848773],"study_design_scores_gemma":[0.0016995637,0.00033665847,0.028281081,0.000014662023,0.0000047955928,9.815465e-7,0.0001422777,0.000038971622,0.95701647,0.0001376933,0.0122188125,0.00010801153],"about_ca_topic_score_codex":0.00011442183,"about_ca_topic_score_gemma":0.00021757392,"teacher_disagreement_score":0.037536297,"about_ca_system_score_codex":0.00004512023,"about_ca_system_score_gemma":0.000070402,"threshold_uncertainty_score":0.34499717},"labels":[],"label_agreement":null},{"id":"W2022690247","doi":"10.1016/j.ejphar.2005.10.054","title":"Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells","year":2005,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Dihydrofolate reductase; Antifolate; Chinese hamster ovary cell; Biology; Methotrexate; Thymidylate synthase; Chinese hamster; Genetics; Mutation; Biochemistry; Gene; Molecular biology; Cell culture; Antimetabolite; Chemotherapy; Immunology","score_opus":0.008987955932876797,"score_gpt":0.3022373487895244,"score_spread":0.2932493928566476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022690247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865744,0.0012479075,0.0059634917,0.0030519164,0.000888353,0.0001118924,0.000019399118,0.000008829054,0.0021337916],"genre_scores_gemma":[0.9921874,0.00014475397,0.003753257,0.0010736763,0.0014448989,0.0000010601404,0.0000071213053,0.000035792502,0.0013520347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988827,0.00019395397,0.00039055766,0.00017687223,0.000092671864,0.0002632299],"domain_scores_gemma":[0.9994065,0.000010271309,0.0001434241,0.00012480105,0.00013116404,0.00018383288],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049021904,0.0001360404,0.00014860187,0.00009528353,0.000065816734,0.000018914936,0.00025264066,0.000029697245,0.0001167036],"category_scores_gemma":[0.000022885974,0.00013583928,0.00009691471,0.000085888154,0.00004371897,0.000006488334,0.00007461605,0.00015935431,0.00008837293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012803092,0.000041343665,0.0000123427035,0.000007217752,0.000059616603,0.00013856351,0.00011840536,0.00789669,0.9510931,0.000009597135,0.039391335,0.0011038102],"study_design_scores_gemma":[0.0006767339,0.00018114584,0.000384579,0.0000084997,0.000042043266,0.000084970634,0.0000139572785,0.00003517922,0.66282415,0.0000037811637,0.33563,0.00011495646],"about_ca_topic_score_codex":2.7872167e-7,"about_ca_topic_score_gemma":0.0000020075918,"teacher_disagreement_score":0.29623866,"about_ca_system_score_codex":0.000014611992,"about_ca_system_score_gemma":0.00004123938,"threshold_uncertainty_score":0.5539365},"labels":[],"label_agreement":null},{"id":"W2022911774","doi":"10.1002/gene.10021","title":"A cre recombinase transgene with mosaic, widespread tamoxifen‐inducible action","year":2002,"lang":"en","type":"article","venue":"genesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cre recombinase; Transgene; Biology; Embryonic stem cell; Tamoxifen; Reporter gene; Molecular biology; Recombinase; Genetically modified mouse; Gene targeting; Gene; Cancer research; Gene expression; Genetics; Cancer; Recombination","score_opus":0.022737399077229645,"score_gpt":0.27620761021048623,"score_spread":0.2534702111332566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022911774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829616,0.0023464188,0.01310854,0.00017591804,0.00017857556,0.00015329986,0.000014951084,0.00003939566,0.0010213028],"genre_scores_gemma":[0.9937366,0.0008521601,0.0020229707,0.00010447807,0.00018053732,0.00004255275,0.000048282036,0.000039792634,0.002972602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991368,0.000021847653,0.00013143085,0.00034801647,0.000107852706,0.00025406227],"domain_scores_gemma":[0.9994448,0.0000062891304,0.000030942534,0.00037533863,0.00004157879,0.000101080885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006415606,0.00016843759,0.00012287583,0.00004466022,0.00007565205,0.000020205365,0.00011271065,0.00011983035,0.00022859666],"category_scores_gemma":[0.000013365971,0.000157643,0.000069369016,0.00012937248,0.000026043863,0.0000040443233,0.000020692642,0.000056184923,0.000034724755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004619758,0.00008367198,0.000863275,0.000031655363,0.00006535718,0.000008806885,0.00010131243,0.0014787912,0.96602803,0.0000039294077,0.0071085393,0.024180416],"study_design_scores_gemma":[0.0006287659,0.00032110463,0.0016187116,0.0000137101215,0.000043628766,0.00006184082,0.00007545522,0.00040369364,0.95005393,0.0000069938833,0.046500713,0.0002714673],"about_ca_topic_score_codex":0.00004142597,"about_ca_topic_score_gemma":0.000077442535,"teacher_disagreement_score":0.039392173,"about_ca_system_score_codex":0.000011754573,"about_ca_system_score_gemma":0.000013567887,"threshold_uncertainty_score":0.64284945},"labels":[],"label_agreement":null},{"id":"W2024580589","doi":"10.1006/mthe.2002.0685","title":"New Editor of Molecular Therapy","year":2002,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Library science; Editorial board; Editor in chief; Management; Computer science","score_opus":0.007478455305309469,"score_gpt":0.2618554791654846,"score_spread":0.2543770238601751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024580589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8284873,0.040711127,0.12705757,0.00031149338,0.0011757008,0.0003395606,0.0000078791,0.000038959184,0.0018704497],"genre_scores_gemma":[0.9895799,0.0036581538,0.0040078643,0.0005858751,0.001176796,0.00001743674,0.000024349227,0.00007132676,0.00087826164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988978,0.00004128853,0.00022503002,0.00033372434,0.00022307974,0.00027908626],"domain_scores_gemma":[0.99916637,0.0000055120504,0.000061999475,0.0005788951,0.000063794505,0.00012345736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007774434,0.00022934975,0.00019479117,0.000059086244,0.000028221253,0.000017034054,0.00028968405,0.00016288379,0.0002503565],"category_scores_gemma":[0.000015929372,0.00022150645,0.0002048111,0.00013672038,0.000038743285,0.0000026379084,0.00003934561,0.00008697558,0.000027807286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004065074,0.0000632292,0.00009156064,0.000004599113,0.00010828892,0.000008604003,0.00007124573,0.00045358506,0.9550624,0.00006058146,0.007105223,0.03693005],"study_design_scores_gemma":[0.0010322884,0.00035327207,0.00012791282,0.000006238662,0.0000049386126,0.000007055,0.00001070758,0.00006979026,0.81559837,0.00007607699,0.18250436,0.00020901607],"about_ca_topic_score_codex":0.00001715856,"about_ca_topic_score_gemma":7.90077e-7,"teacher_disagreement_score":0.17539912,"about_ca_system_score_codex":0.000006241676,"about_ca_system_score_gemma":0.000023871666,"threshold_uncertainty_score":0.9032771},"labels":[],"label_agreement":null},{"id":"W2026246638","doi":"10.1385/mb:29:3:197","title":"Reaction Parameters of Targeted Gene Repair in Mammalian Cells","year":2005,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Electroporation; Oligonucleotide; Biology; DNA; Molecular biology; Population; Gene; Genetics; Nucleotide excision repair; Gene targeting; Cell; DNA repair; Cell biology","score_opus":0.003947044081195193,"score_gpt":0.23970395497499794,"score_spread":0.23575691089380274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026246638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842165,0.0012481053,0.013716884,0.0004377417,0.00008794659,0.0001508319,0.000011084818,0.000053100517,0.00007779498],"genre_scores_gemma":[0.9711996,0.00017175896,0.02834147,0.00012282735,0.000023848244,0.000014130984,0.000034356195,0.000023549035,0.00006848157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990578,0.000027346161,0.0002572222,0.0003306131,0.00007552307,0.0002514441],"domain_scores_gemma":[0.9994098,0.000003130308,0.00006013037,0.00046691584,0.000023984467,0.000036069487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011138836,0.00014092363,0.00015994845,0.0001784313,0.00001287924,0.0000020178418,0.00016103442,0.00042844634,0.0000051348484],"category_scores_gemma":[0.000039602295,0.00015946588,0.000104138795,0.00019690018,0.0000779099,0.000001836318,0.0000814053,0.00013610789,0.0000076136257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023940715,0.000046047982,0.000118916156,0.000010840779,0.000024782545,0.000011935963,0.000009383564,0.0020920855,0.99194103,0.00006149181,0.00015291576,0.0055066296],"study_design_scores_gemma":[0.0003443017,0.00017505248,0.0006177564,0.000005838828,0.000010035362,0.000020917758,0.000019038149,0.00037081598,0.9852853,0.00002411894,0.012970452,0.00015638159],"about_ca_topic_score_codex":0.000049596787,"about_ca_topic_score_gemma":0.0000648171,"teacher_disagreement_score":0.014624587,"about_ca_system_score_codex":0.000018126344,"about_ca_system_score_gemma":0.000020240803,"threshold_uncertainty_score":0.650283},"labels":[],"label_agreement":null},{"id":"W2026291301","doi":"10.1007/s10530-013-0477-0","title":"Genetic control of invasive fish: technological options and its role in integrated pest management","year":2013,"lang":"en","type":"article","venue":"Biological Invasions","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"Minnesota Sea Grant, University of Minnesota; International Atomic Energy Agency","keywords":"Biology; Sterile insect technique; Pest control; Integrated pest management; PEST analysis; Population; Invasive species; Gene drive; Biotechnology; Trojan horse; Ecology; Genetics; Gene; CRISPR; Environmental health; Computer science","score_opus":0.030373123990632973,"score_gpt":0.2521581594438086,"score_spread":0.22178503545317563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026291301","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99536294,0.001299503,0.0022432911,0.00020398812,0.000024234421,0.00044944556,0.000027524287,0.000020984296,0.00036812102],"genre_scores_gemma":[0.995808,0.002052615,0.0017239368,0.00013425018,0.000018556575,0.00015904605,0.000033282377,0.0000067611804,0.00006352934],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991602,0.000051899355,0.00023775332,0.0002868511,0.000051441384,0.00021191075],"domain_scores_gemma":[0.99962264,0.000042855434,0.00003782283,0.00017165666,0.000050136,0.00007488608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008082028,0.00013689755,0.00017097213,0.000072466064,0.0000356982,0.000010088949,0.00016101818,0.00022789164,0.000075009084],"category_scores_gemma":[0.00019697177,0.00009998091,0.000049798167,0.00013993403,0.00012208919,0.0000026035777,0.00016186967,0.00010777159,0.000011902512],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014657177,0.00013247461,0.019065617,0.000015559628,0.000034660898,0.000006032224,0.000011169844,0.00032992943,0.9757745,0.0012739326,0.0001502183,0.0031911938],"study_design_scores_gemma":[0.0015573736,0.00083897635,0.803091,0.000083163366,0.000033608798,0.00004001737,0.0008152031,0.001149551,0.186641,0.001228621,0.0040374245,0.00048405494],"about_ca_topic_score_codex":0.000018959996,"about_ca_topic_score_gemma":0.00003446823,"teacher_disagreement_score":0.78913355,"about_ca_system_score_codex":0.0000075605763,"about_ca_system_score_gemma":0.000012011597,"threshold_uncertainty_score":0.4077103},"labels":[],"label_agreement":null},{"id":"W202631039","doi":"10.1007/978-1-4614-8585-8_4","title":"Methods and Role of Embryo Rescue Technique in Alien Gene Transfer","year":2013,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada); University of Saskatchewan","funders":"","keywords":"Alien; Gene transfer; Biology; Embryo; Computational biology; Gene; Genetics; Political science; Law","score_opus":0.00713745174591771,"score_gpt":0.29854961495577315,"score_spread":0.2914121632098554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W202631039","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0140442485,0.017781146,0.32748705,0.000045056113,0.000101406506,0.0012453472,0.000056199206,0.000030759904,0.6392088],"genre_scores_gemma":[0.22333823,0.008871816,0.2974857,0.00018323178,0.0003633341,0.00021926744,0.00026085548,0.0002801949,0.46899736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926907,0.00001493649,0.00024200274,0.00028848488,0.000056745976,0.00012877726],"domain_scores_gemma":[0.9996122,0.0000076551205,0.000016301214,0.00028122892,0.000033906002,0.00004868221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016550891,0.0001953456,0.00024799455,0.00007833346,0.000007983878,0.0000051835336,0.00010311511,0.00043463238,0.00012974626],"category_scores_gemma":[0.0000072581356,0.00018365408,0.00007380593,0.000011863266,0.000045329052,9.182313e-7,0.000065155305,0.0001200191,0.0000018829337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008528999,0.000005255961,0.000005123084,0.000039259947,0.000031336593,7.9706484e-7,0.000017884104,0.0000365869,0.9841624,0.0019889814,0.00007875994,0.013625097],"study_design_scores_gemma":[0.00014248543,0.00009465206,0.0000584595,0.000032094384,0.000018108549,0.000013752238,0.000008907571,0.00003756175,0.9290858,0.001057883,0.06923637,0.00021391988],"about_ca_topic_score_codex":0.000065496984,"about_ca_topic_score_gemma":0.00006270218,"teacher_disagreement_score":0.20929398,"about_ca_system_score_codex":0.00000490234,"about_ca_system_score_gemma":0.0000223382,"threshold_uncertainty_score":0.7489196},"labels":[],"label_agreement":null},{"id":"W2030267802","doi":"10.1007/s00299-010-0936-3","title":"Unprecedented enhancement of transient gene expression from minimal cassettes using a double terminator","year":2010,"lang":"en","type":"article","venue":"Plant Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Ohio Agricultural Research and Development Center, Ohio State University","keywords":"Biology; Terminator (solar); Gene; Gene expression; Genetics; Transient (computer programming); Plant biochemistry; Cell biology; Molecular biology; Computational biology; Computer science","score_opus":0.008514272562400633,"score_gpt":0.2645368865240167,"score_spread":0.2560226139616161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030267802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99551666,0.00025278013,0.0034432695,0.000004942828,0.00041701487,0.00013485961,0.000033249376,0.0000068854292,0.00019034834],"genre_scores_gemma":[0.9936995,0.000030325695,0.005759723,0.000009641856,0.000109790584,0.00000879924,0.0002686257,0.000014381673,0.000099206285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991263,0.0000073640786,0.00028808176,0.00028479015,0.0001316549,0.0001617805],"domain_scores_gemma":[0.99946207,0.0000068578565,0.00012410535,0.00030343755,0.000033044285,0.000070496215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083735664,0.00012381817,0.00013255353,0.000027864702,0.000028627635,0.000008744094,0.0000640694,0.000104527535,0.00005184418],"category_scores_gemma":[0.000007976314,0.0001159369,0.00006133292,0.000026981583,0.000019899524,0.0000021292994,0.00004139192,0.00007067335,5.7428895e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005526109,0.0000719113,0.001967196,0.00002139786,0.000013642538,0.00007349448,0.00009409937,0.00015331492,0.9972811,9.645795e-8,0.0001805936,0.00008790294],"study_design_scores_gemma":[0.00028328097,0.000051735024,0.0005925479,0.000022522787,0.000024300956,0.00011141383,0.000020736987,0.00023517852,0.9940768,0.000001720374,0.004444961,0.00013481433],"about_ca_topic_score_codex":0.0000881964,"about_ca_topic_score_gemma":0.0000363065,"teacher_disagreement_score":0.0042643673,"about_ca_system_score_codex":0.0000046257514,"about_ca_system_score_gemma":0.00003710036,"threshold_uncertainty_score":0.47277695},"labels":[],"label_agreement":null},{"id":"W2030710746","doi":"10.4161/worm.28641","title":"Silent no more","year":2014,"lang":"en","type":"article","venue":"Worm","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Ulster University","keywords":"Biology; Piwi-interacting RNA; RNA interference; Argonaute; Genetics; RNA; Epigenetics; Genome; RasiRNA; Germline; Gene silencing; RNA silencing; XIST; Transcriptome; Gene; Long non-coding RNA; Gene expression; X-inactivation","score_opus":0.003481797434369202,"score_gpt":0.2643613927565303,"score_spread":0.2608795953221611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030710746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9266519,0.0006512257,0.03518735,0.00029375617,0.0005064199,0.00009426634,0.0000034042525,0.000032683332,0.03657901],"genre_scores_gemma":[0.99616945,0.000026318748,0.00096760754,0.00029449144,0.0003489982,0.000005082785,0.000018471781,0.000009361989,0.0021602232],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996957,0.000003861475,0.000050500614,0.00010714276,0.000040939885,0.00010182396],"domain_scores_gemma":[0.9997653,0.0000021531846,0.000008421591,0.00017016972,0.000016863278,0.000037139467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041702857,0.000053523974,0.000040670773,0.000008776088,0.000017442842,0.0000056475296,0.00006284276,0.000040001432,0.000030276613],"category_scores_gemma":[0.000025074994,0.00005002072,0.000030221458,0.000018108272,0.000011451529,3.2283327e-7,0.000032575088,0.000026791326,0.000068055895],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015473504,0.00002536283,0.0013362402,0.000018847648,0.000020151178,8.2909094e-7,0.0000627559,0.0007708032,0.95893085,0.00015235013,0.022217434,0.016448915],"study_design_scores_gemma":[0.00021622008,0.00010016306,0.0050062607,0.000005947704,0.0000052459213,0.0000045454644,0.000015623105,0.0006291417,0.28749934,0.000019974146,0.7063595,0.00013802582],"about_ca_topic_score_codex":0.0000027288597,"about_ca_topic_score_gemma":0.0000034310694,"teacher_disagreement_score":0.6841421,"about_ca_system_score_codex":0.0000024563392,"about_ca_system_score_gemma":0.00000471247,"threshold_uncertainty_score":0.20397858},"labels":[],"label_agreement":null},{"id":"W2031033815","doi":"10.1016/j.bbrc.2008.01.065","title":"A novel lineage-specific hypersensitive site is essential for position independent granzyme B expression in transgenic mice","year":2008,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Canada Research Chairs; University of Alberta; Canadian Cancer Society","keywords":"Transgene; Granzyme B; Lineage (genetic); Genetically modified mouse; Biology; Cell biology; Granzyme; Gene; Molecular biology; Genetics; Perforin; T cell; Immune system; CD8","score_opus":0.05270028288084236,"score_gpt":0.3698839420861318,"score_spread":0.31718365920528946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031033815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882509,0.0014794754,0.008875118,0.0008131514,0.000021492397,0.00036182042,0.000116215844,0.000009659318,0.00007215104],"genre_scores_gemma":[0.99180824,0.0025586328,0.0048518074,0.000056980105,0.0001893735,0.000097955744,0.00034224582,0.00001565111,0.00007911583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989073,0.000062195446,0.00018693694,0.00034996154,0.00020654855,0.0002870085],"domain_scores_gemma":[0.9990654,0.00011427619,0.000021032241,0.0004976774,0.00017803007,0.00012359417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871167,0.00012308502,0.0001336848,0.00007488061,0.00022738837,0.00001986785,0.00027585457,0.00015901512,0.0000033476604],"category_scores_gemma":[0.00005911952,0.000116750474,0.00009490127,0.00019946476,0.00036276501,0.0000061369196,0.00022037988,0.00027138094,0.0000045626916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014483917,0.0003182094,0.000029651059,0.000017628385,0.0000097500015,5.558851e-7,0.00022379687,0.000003103313,0.99805397,0.00007470454,0.0009148293,0.0002089802],"study_design_scores_gemma":[0.000768162,0.00013724784,0.0016593167,0.00003306903,0.0000054777975,0.0000118538155,0.00008593266,0.00086766266,0.99179465,0.000032392392,0.004455859,0.00014840919],"about_ca_topic_score_codex":0.000029710662,"about_ca_topic_score_gemma":0.0000122970705,"teacher_disagreement_score":0.0062593347,"about_ca_system_score_codex":0.000020342466,"about_ca_system_score_gemma":0.00004127255,"threshold_uncertainty_score":0.4760946},"labels":[],"label_agreement":null},{"id":"W2031486396","doi":"10.1371/journal.pgen.1000522","title":"Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for Mutation Screening","year":2009,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal University Hospital","funders":"National Human Genome Research Institute; Vlaamse regering; National Institutes of Health; Universiteit Gent; Fonds Wetenschappelijk Onderzoek","keywords":"Biology; Genetics; DNA; Mutation; Coding region; Promoter; Gene; Conserved sequence; Computational biology; Base sequence; Gene expression","score_opus":0.02279365488847326,"score_gpt":0.30116365685002383,"score_spread":0.2783700019615506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031486396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7192969,0.0005606042,0.27903798,0.0006335391,0.000024427889,0.0004015636,0.000013347862,0.000015547921,0.000016098935],"genre_scores_gemma":[0.9954001,0.000063515865,0.0040335683,0.00012736257,0.00017624079,0.000069350084,0.00009737476,0.000020361018,0.000012162087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993177,0.00002202617,0.00015269927,0.00026169702,0.000063770065,0.0001821177],"domain_scores_gemma":[0.99949396,0.00003766124,0.000087668275,0.00020959847,0.00010324209,0.00006789787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010843664,0.00014758081,0.000092494214,0.000032068394,0.0002507851,0.00006897912,0.00007260092,0.000054648215,7.338204e-7],"category_scores_gemma":[0.000032809465,0.00011090906,0.000042129108,0.00006384489,0.000051224193,0.0000087544795,0.000025442252,0.000060840477,1.5661573e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065039945,0.000024825067,0.0015469454,0.00003929684,0.000049476213,4.3044298e-7,0.000275969,0.0055209994,0.9806728,0.00002914806,0.000030251642,0.011744852],"study_design_scores_gemma":[0.00063697627,0.00055589445,0.040815804,0.0001456413,0.00015719181,0.000052647167,0.0008066196,0.11034151,0.8452604,0.00023358737,0.000587461,0.00040628813],"about_ca_topic_score_codex":0.0000014402169,"about_ca_topic_score_gemma":0.000017154744,"teacher_disagreement_score":0.2761032,"about_ca_system_score_codex":0.000012935098,"about_ca_system_score_gemma":0.00003184243,"threshold_uncertainty_score":0.452274},"labels":[],"label_agreement":null},{"id":"W2031984687","doi":"10.1016/j.tim.2014.01.007","title":"To acquire or resist: the complex biological effects of CRISPR–Cas systems","year":2014,"lang":"en","type":"review","venue":"Trends in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Computational biology; DNA; Palindrome; Genetics; Gene","score_opus":0.04346834040777872,"score_gpt":0.39200758900864907,"score_spread":0.3485392486008704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031984687","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00044100432,0.9965455,0.0015764234,0.000030424384,0.0006124334,0.0005174754,0.00010392749,0.000013987274,0.0001588576],"genre_scores_gemma":[0.0074811904,0.9895003,0.00034137713,0.00011184605,0.00040381134,0.00019826884,0.0008951166,0.000057904555,0.0010101752],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977588,0.0004736585,0.00069284276,0.0005996366,0.000037975115,0.00043706028],"domain_scores_gemma":[0.99874556,0.00021195161,0.00020217207,0.00073935714,0.00003477881,0.00006615968],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033033246,0.00044673725,0.0014735566,0.00022123111,0.000040669966,0.000011321181,0.0006999989,0.0007193726,0.000032199157],"category_scores_gemma":[0.00015680074,0.00025265507,0.00033835412,0.0003264461,0.0001668529,6.108539e-7,0.0003452238,0.00021979497,0.000022669858],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001495665,0.00014599836,0.00003883349,0.012783672,0.00050651736,0.000037388683,0.00009431597,0.00013884407,0.12934259,0.0001228099,0.029104155,0.82753533],"study_design_scores_gemma":[0.00023466855,0.0005301859,0.0000648203,0.0010983081,0.00010667371,0.00015589662,0.000008926562,0.0000017997228,0.0019979551,0.0000012108798,0.9954824,0.00031716502],"about_ca_topic_score_codex":0.000024514728,"about_ca_topic_score_gemma":0.00008144122,"teacher_disagreement_score":0.9663782,"about_ca_system_score_codex":0.000030372474,"about_ca_system_score_gemma":0.00004795439,"threshold_uncertainty_score":0.99999255},"labels":[],"label_agreement":null},{"id":"W2032284140","doi":"10.1002/1526-968x(200011/12)28:3/4<147::aid-gene90>3.0.co;2-g","title":"Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon cre-mediated excision","year":2000,"lang":"en","type":"article","venue":"genesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":832,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; Sunnybrook Health Science Centre","funders":"Medical Research Council; Cancer Care Ontario","keywords":"Cre recombinase; Green fluorescent protein; Biology; Transgene; Molecular biology; Recombinase; lac operon; Embryonic stem cell; Reporter gene; Cre-Lox recombination; Genetically modified mouse; Gene; Cell culture; Gene knockin; Cell biology; Genetics; Gene expression","score_opus":0.01192882819464259,"score_gpt":0.2719604343695559,"score_spread":0.26003160617491333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032284140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933057,0.0013208954,0.0043556,0.00008618752,0.00007200924,0.00040544482,0.00001703202,0.000054832122,0.00038228754],"genre_scores_gemma":[0.991239,0.00056308636,0.001243361,0.00007847678,0.00029187262,0.00012369637,0.00019402926,0.000047082678,0.0062193763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987194,0.00002495988,0.00026722508,0.0004670452,0.0001964681,0.00032493382],"domain_scores_gemma":[0.99918604,0.000005461079,0.00005928998,0.00056786294,0.00005828633,0.00012304109],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011222811,0.00022115026,0.00017956826,0.00004549302,0.00006581466,0.000028511933,0.00018038593,0.00017454117,0.00036720262],"category_scores_gemma":[0.000018595716,0.00020496087,0.00010553395,0.00009134355,0.000022472737,0.0000052552546,0.000072124014,0.000056367906,0.000050797462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026931358,0.00006054839,0.00009047507,0.000033600827,0.00003233756,0.000009014093,0.000075037125,0.00080719596,0.98205316,3.4546397e-7,0.0006719141,0.015897058],"study_design_scores_gemma":[0.0007408051,0.00014640852,0.00085858395,0.000023007966,0.00001711683,0.00000959446,0.000029225552,0.00014731883,0.97055256,0.00000428864,0.027212093,0.0002589789],"about_ca_topic_score_codex":0.00013534776,"about_ca_topic_score_gemma":0.00006934266,"teacher_disagreement_score":0.026540179,"about_ca_system_score_codex":0.000012545396,"about_ca_system_score_gemma":0.00003288797,"threshold_uncertainty_score":0.8358062},"labels":[],"label_agreement":null},{"id":"W2032492326","doi":"10.1016/j.worlddev.2013.10.023","title":"The Politics of Technological Upgrading: International Transfer to and Adaptation of GM Cotton in Argentina","year":2013,"lang":"en","type":"article","venue":"World Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Consejo Nacional de Investigaciones Científicas y Técnicas; International Development Research Centre","keywords":"Multinational corporation; Negotiation; Scope (computer science); Politics; Adaptation (eye); Technology transfer; Business; Economic system; International trade; Economics; Political science; Biology","score_opus":0.010349931842313864,"score_gpt":0.25916062136178075,"score_spread":0.2488106895194669,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032492326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890505,0.00019878199,0.009990722,0.00028455572,0.000035658595,0.00010556355,8.8201165e-7,0.0000021997682,0.00033110016],"genre_scores_gemma":[0.9943924,0.00003979815,0.0051392484,0.000018178558,0.0000064918427,0.000018583949,0.0000056982867,0.0000029534588,0.00037665624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961895,0.000005046955,0.0001635278,0.00007613831,0.000059728805,0.00007660673],"domain_scores_gemma":[0.99987674,0.000007985952,0.00000928976,0.000055135548,0.000031345455,0.000019523277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008071226,0.000042217853,0.000047795293,0.000051635092,0.000015292564,0.000004268802,0.00006786667,0.000023080973,0.0000062288063],"category_scores_gemma":[0.000023923789,0.000032661123,0.000010462865,0.000061043174,0.000026347721,8.8830967e-7,0.00003332934,0.00002383367,7.738551e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026221653,0.000083977706,0.035818595,0.00003325348,0.000060129303,6.298027e-7,0.0008494834,0.0008462119,0.8668575,0.007393925,0.00038150907,0.087648526],"study_design_scores_gemma":[0.00021648349,0.00003481001,0.1315571,0.000021400308,0.0000020694904,0.0000015589299,0.00032307164,0.00030324265,0.7966896,0.00011385317,0.07065405,0.00008269752],"about_ca_topic_score_codex":0.000008825417,"about_ca_topic_score_gemma":0.00009357048,"teacher_disagreement_score":0.09573851,"about_ca_system_score_codex":0.0000074216814,"about_ca_system_score_gemma":0.00001541619,"threshold_uncertainty_score":0.13318819},"labels":[],"label_agreement":null},{"id":"W2032843495","doi":"10.1186/bcr1902","title":"Accurate prediction of BRCA1 and BRCA2 heterozygous genotypes using expression profiling of lymphocytes after irradiation-induced DNA damage","year":2008,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"National Cancer Institute; Biotechnology and Biological Sciences Research Council; Medical Research Council; Allergan; Keele University; Ministerio de Economía y Competitividad; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Tenovus; Breast Cancer Campaign; Breast Cancer Research Trust; World Cancer Research Fund; University of Sheffield; National Health and Medical Research Council; Cancer Research UK; European Commission; Royal Marsden NHS Foundation Trust; John and Lucille Van Geest Foundation; University of Bristol; University of Glasgow; Ludwig Institute for Cancer Research; AstraZeneca","keywords":"Surgical oncology; DNA damage; Genotype; Gene expression profiling; DNA profiling; DNA repair; Biology; Genetics; Cancer research; DNA; Medicine; Gene expression; Oncology; Gene","score_opus":0.04381490101314298,"score_gpt":0.3648209288304947,"score_spread":0.3210060278173517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032843495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99732786,0.0016875307,0.00059978367,0.000013686359,0.00005283552,0.0001746925,0.000107128,0.0000051170164,0.000031378135],"genre_scores_gemma":[0.9988112,0.00047930688,0.00047288238,0.0000043155483,0.00014738998,0.000032323536,0.000015278934,0.000017567963,0.00001974528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911827,0.00005580793,0.00017997208,0.00022714848,0.00021959167,0.00019920924],"domain_scores_gemma":[0.9994767,0.000013526158,0.00004728118,0.00019999791,0.0002020379,0.000060509257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017650257,0.0000871524,0.00011544641,0.0000902306,0.00007137616,0.000007877298,0.0000860385,0.00008985801,0.00001711443],"category_scores_gemma":[0.000026556563,0.00008275489,0.000031685064,0.00012071718,0.000088421664,0.0000085211805,0.000100801335,0.0000721807,3.6778613e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019771843,0.000021200507,0.012479566,0.00009727616,0.000021634658,0.0000023201396,0.00016338222,0.0011572468,0.9850273,9.93306e-7,0.000014326208,0.0008170366],"study_design_scores_gemma":[0.00036036066,0.00006595427,0.16850364,0.000055713186,0.000005542386,0.00003851834,0.00004984031,0.0019989337,0.82882994,0.0000028350303,0.000027952816,0.000060771756],"about_ca_topic_score_codex":0.00024284997,"about_ca_topic_score_gemma":0.000011913607,"teacher_disagreement_score":0.15619735,"about_ca_system_score_codex":0.000033071014,"about_ca_system_score_gemma":0.00016067724,"threshold_uncertainty_score":0.33746463},"labels":[],"label_agreement":null},{"id":"W2034012805","doi":"10.1021/bi800925e","title":"Distortion-Dependent Unhooking of Interstrand Cross-Links in Mammalian Cell Extracts","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"National Cancer Institute","keywords":"Distortion (music); Chemistry; Cell; Biophysics; Physics; Biology; Biochemistry; Optoelectronics","score_opus":0.008163567659365172,"score_gpt":0.276267104436523,"score_spread":0.26810353677715787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034012805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948845,0.0012705635,0.0016691305,0.0000131748275,0.00010499255,0.0000608938,0.000015298294,0.0000078101275,0.00197365],"genre_scores_gemma":[0.99813896,0.000116447,0.00028944618,0.000016348164,0.00011948872,0.0000069387934,0.00006031491,0.000017474913,0.0012346014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991436,0.000007539263,0.00026679473,0.00027194258,0.00011382596,0.00019627748],"domain_scores_gemma":[0.9995426,0.000005518862,0.000066687484,0.00027791446,0.000037061185,0.000070218324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007988028,0.00013615449,0.00012359898,0.000028112378,0.000030120398,0.0000070777915,0.00015754081,0.00025230393,0.00002615856],"category_scores_gemma":[0.000030477728,0.00015136311,0.000077056095,0.000054731245,0.00007969374,0.0000024334722,0.000055665267,0.00014784603,0.0000024182934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040500898,0.000066416455,0.02723845,0.000086920794,0.0000075061084,0.000016003783,0.00006663185,0.00036893337,0.9717489,5.818506e-7,0.00017781816,0.00018137592],"study_design_scores_gemma":[0.0005450803,0.000038576276,0.016527131,0.000022514783,0.0000045509078,0.00003463107,0.000051440027,0.000022625787,0.9820535,0.000002908885,0.00053751736,0.00015947803],"about_ca_topic_score_codex":0.000023405826,"about_ca_topic_score_gemma":0.00001002766,"teacher_disagreement_score":0.010711318,"about_ca_system_score_codex":0.000022102533,"about_ca_system_score_gemma":0.00005597074,"threshold_uncertainty_score":0.61724085},"labels":[],"label_agreement":null},{"id":"W2034201571","doi":"10.1128/jb.02333-14","title":"Role of the Streptococcus mutans CRISPR-Cas Systems in Immunity and Cell Physiology","year":2014,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Plasmid; Streptococcus mutans; Cas9; Transformation (genetics); Virulence; Heat shock; Transduction (biophysics); Gene; Microbiology; Genetics; Bacteria; Heat shock protein; Biochemistry","score_opus":0.00381523081698011,"score_gpt":0.24040472114634434,"score_spread":0.23658949032936424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034201571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975677,0.0013674885,0.0005845062,0.000043463064,0.00024382133,0.00006866091,0.0000045348193,9.268799e-7,0.000118891396],"genre_scores_gemma":[0.9995652,0.00017343769,0.000072000454,0.00002630382,0.00013489235,0.0000020407836,0.000001977055,0.000007644986,0.000016489026],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992403,0.00017209676,0.00032664975,0.00009278232,0.000039009563,0.00012919407],"domain_scores_gemma":[0.999444,0.000031925574,0.00021570464,0.00019837996,0.00007561971,0.000034346132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025537904,0.000087603046,0.00023635809,0.00004316388,0.000019587478,0.0000043197965,0.00018013737,0.00012618411,0.00000381569],"category_scores_gemma":[0.00008048075,0.00006152556,0.000060881528,0.000047088717,0.000079463374,0.0000023544703,0.000091049355,0.00015372645,3.3726357e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004126373,0.000025731495,0.010865583,0.000025351637,0.000016887108,4.022478e-7,0.00008575008,0.0008972469,0.9875042,0.000023717663,0.000023407869,0.00049046933],"study_design_scores_gemma":[0.00062642904,0.0005378287,0.5153307,0.000027201679,0.000016843444,0.00009759288,0.00028373816,0.00027283703,0.47547147,0.00010307051,0.0071430234,0.0000892689],"about_ca_topic_score_codex":0.000034342225,"about_ca_topic_score_gemma":0.000030432351,"teacher_disagreement_score":0.51203275,"about_ca_system_score_codex":0.000007034413,"about_ca_system_score_gemma":0.00003311367,"threshold_uncertainty_score":0.25089395},"labels":[],"label_agreement":null},{"id":"W2034451231","doi":"10.1016/j.copbio.2005.06.004","title":"Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design","year":2005,"lang":"en","type":"review","venue":"Current Opinion in Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":439,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Rational design; Directed evolution; Protein engineering; Directed Molecular Evolution; Mutagenesis; Computational biology; Enzyme; Synthetic biology; Function (biology); Computer science; Biochemical engineering; Biology; Gene; Biochemistry; Mutation; Genetics; Engineering; Mutant","score_opus":0.10811056712837536,"score_gpt":0.3397796550552685,"score_spread":0.23166908792689317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034451231","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025793316,0.9253386,0.073063664,0.00013185071,0.0005959216,0.0005426592,0.00003544209,0.000030990093,0.0000029061782],"genre_scores_gemma":[0.0058485386,0.9916171,0.0017782596,0.0000018382744,0.00031565083,0.0001954411,0.00020834121,0.000028500697,0.000006334176],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99890935,0.0000608675,0.0003374217,0.0003846012,0.00010505182,0.0002027278],"domain_scores_gemma":[0.99949044,0.00006580328,0.00012391033,0.00026032887,0.000024070094,0.000035426205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002202006,0.0002552292,0.0004214059,0.00027286544,0.000038938506,0.000011275711,0.00020830063,0.00048747665,0.0000019931822],"category_scores_gemma":[0.00012474255,0.00021999657,0.00007962359,0.00030514994,0.00005836757,0.000003835633,0.00018546816,0.0003157095,0.0000013792559],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001640552,0.00009438423,0.000014667058,0.002067196,0.00008894254,7.215004e-8,0.000032205513,0.028105278,0.0018689499,0.0047675474,0.00037186206,0.9625725],"study_design_scores_gemma":[0.00035210114,0.00019181897,0.00023252027,0.003121875,0.00006517444,0.000050539238,0.000010173899,0.008805303,0.0041516945,0.000026083457,0.9824504,0.000542319],"about_ca_topic_score_codex":0.0000016469548,"about_ca_topic_score_gemma":0.0000019233112,"teacher_disagreement_score":0.98207855,"about_ca_system_score_codex":0.000042008214,"about_ca_system_score_gemma":0.00009827972,"threshold_uncertainty_score":0.89712},"labels":[],"label_agreement":null},{"id":"W2035241943","doi":"10.1007/s00294-003-0441-0","title":"Characterization and expression of the Neurospora crassa nmt-1 gene","year":2003,"lang":"en","type":"article","venue":"Current Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neurospora crassa; Biology; Gene; Gene expression; Genetics; Neurospora; Proteomics; Computational biology; Cell biology; Mutant","score_opus":0.010192222799267967,"score_gpt":0.27491915090907626,"score_spread":0.2647269281098083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035241943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738065,0.002763342,0.022776213,0.000014118327,0.00046878113,0.00011423564,0.000013295857,0.0000037800298,0.00003975024],"genre_scores_gemma":[0.997839,0.0015314785,0.0004288477,0.000019645917,0.000060008162,0.000004687991,0.000029754621,0.000013193089,0.00007342706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948347,0.000029922378,0.00013389587,0.00016294759,0.00008255355,0.00010722571],"domain_scores_gemma":[0.99960834,0.0000027788806,0.00005575464,0.00025569138,0.00003801621,0.000039434293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000052446256,0.000091550944,0.000068596695,0.000014465,0.000039216367,0.000008516876,0.000087412474,0.000050960356,0.0000048918705],"category_scores_gemma":[0.000033858945,0.00007333469,0.00003606459,0.000054359625,0.00003948758,0.0000010926258,0.00006554506,0.000047895945,5.3518136e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000026999198,0.000019698851,0.011549887,0.000020109857,0.0000024820715,6.433136e-8,0.000025096224,0.00014478306,0.9846871,0.000017002698,0.00006373189,0.0034673407],"study_design_scores_gemma":[0.00015485157,0.000030333576,0.03788581,0.000011930089,0.000009496807,0.000004363584,0.0000058171445,0.000075019554,0.9193345,0.000011275663,0.042397764,0.00007887483],"about_ca_topic_score_codex":1.9094509e-7,"about_ca_topic_score_gemma":5.010992e-7,"teacher_disagreement_score":0.06535264,"about_ca_system_score_codex":0.000002149639,"about_ca_system_score_gemma":0.000020323812,"threshold_uncertainty_score":0.29905018},"labels":[],"label_agreement":null},{"id":"W2035986309","doi":"10.1073/pnas.1117984109","title":"Monomeric site-specific nucleases for genome editing","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nuclease; Zinc finger nuclease; Genome editing; Homing endonuclease; Biology; Zinc finger; DNA; Endonuclease; Genome; Computational biology; Genetics; Cell biology; Gene","score_opus":0.031041855114722777,"score_gpt":0.318401275912346,"score_spread":0.2873594207976232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035986309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967229,0.0012645051,0.00006190508,0.0002451083,0.00003252984,0.00010722734,0.000017586426,0.00000320603,0.0015450564],"genre_scores_gemma":[0.99604416,0.000053446005,0.0032682943,0.00006940905,0.0004801034,0.000008925404,5.1685237e-7,0.0000039906695,0.00007115348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941176,0.0000011051297,0.00013471367,0.000111642345,0.0002094493,0.00013132842],"domain_scores_gemma":[0.9997492,0.000016525128,0.00011353837,0.000005324725,0.00008905664,0.000026351532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041265786,0.000053143056,0.00006218345,0.000038836315,0.000083681676,0.000007562476,0.00024529165,0.000042089006,0.0000050093295],"category_scores_gemma":[0.00014127379,0.00003985012,0.00005734736,0.00013177127,0.0001570998,0.000011219398,0.000069256486,0.000032144446,5.454133e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004656508,0.00001388348,0.0028429898,0.000022494309,0.0000050176154,1.1994039e-10,0.00004547792,0.0002038366,0.99433273,0.0016142649,0.0006784316,0.00023624541],"study_design_scores_gemma":[0.000094360184,0.000040604325,0.03765432,0.000011423495,0.0000054826833,0.0000029536438,0.0001225097,0.00016036845,0.94424784,0.0005572687,0.017036097,0.00006676159],"about_ca_topic_score_codex":4.0930857e-7,"about_ca_topic_score_gemma":6.37974e-9,"teacher_disagreement_score":0.05008485,"about_ca_system_score_codex":0.00000574457,"about_ca_system_score_gemma":0.000005482033,"threshold_uncertainty_score":0.16250408},"labels":[],"label_agreement":null},{"id":"W2036005489","doi":"10.1038/ncomms3087","title":"CRISPR-Cas and restriction–modification systems are compatible and increase phage resistance","year":2013,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":297,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Center for Northern Studies; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Plasmid; DNA; Nucleic acid; Biology; Bacteria; Genetics; Bacterial conjugation; Computational biology; Phagemid; Bacteriophage; Gene; Escherichia coli","score_opus":0.01289483957542604,"score_gpt":0.3134063451512129,"score_spread":0.3005115055757869,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036005489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81564873,0.16850363,0.0072588087,0.003425959,0.00018509508,0.0007783021,0.00006821591,0.00006793305,0.004063314],"genre_scores_gemma":[0.9917883,0.0050609782,0.002464283,0.00007109587,0.000049054866,0.000085536034,0.00012790333,0.000011752306,0.0003410845],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99947876,0.000058658894,0.00013297598,0.00017191906,0.00006025944,0.00009741094],"domain_scores_gemma":[0.99888235,0.000037942365,0.000061730694,0.0008255486,0.00012240263,0.00007001564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007404575,0.00009035462,0.000084600964,0.00004180865,0.00018694752,0.000060835726,0.00020833981,0.0001629296,0.0000019937386],"category_scores_gemma":[0.00009911235,0.000091625705,0.000015927075,0.00009264464,0.00006974434,0.000008010967,0.00014149044,0.00020768085,0.0000035474163],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066943045,0.00038310577,0.09395782,0.00040571598,0.00023294735,0.0000026483199,0.00063729665,0.00040017767,0.74991935,0.023230888,0.12715644,0.0036066927],"study_design_scores_gemma":[0.0009587676,0.00008045627,0.704082,0.000121522455,0.00008181601,0.000050472943,0.0010613963,0.006356433,0.018120576,0.00033498293,0.2681422,0.0006093573],"about_ca_topic_score_codex":0.00010132144,"about_ca_topic_score_gemma":0.00024796271,"teacher_disagreement_score":0.73179877,"about_ca_system_score_codex":0.0000099133595,"about_ca_system_score_gemma":0.000012614004,"threshold_uncertainty_score":0.37363878},"labels":[],"label_agreement":null},{"id":"W2036488704","doi":"10.1007/s12033-012-9613-9","title":"Biological and Biomedical Applications of Engineered Nucleases","year":2012,"lang":"en","type":"review","venue":"Molecular Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Waterloo","funders":"Division of Graduate Education; Priority Academic Program Development of Jiangsu Higher Education Institutions; National Natural Science Foundation of China","keywords":"Transcription activator-like effector nuclease; Zinc finger nuclease; Genome editing; Genome engineering; Genetic enhancement; Computational biology; Biology; Gene; Gene targeting; Genetic engineering; CRISPR; Genetics","score_opus":0.01433072264438011,"score_gpt":0.3139258708535893,"score_spread":0.2995951482092092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036488704","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00031036875,0.9452625,0.05377359,0.00002564813,0.00006058406,0.0004216793,0.000072261115,0.000032811586,0.00004053715],"genre_scores_gemma":[0.0041722315,0.99219275,0.002961143,0.000011906997,0.0000981311,0.00012962878,0.00036366924,0.00004811694,0.000022418151],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998745,0.000043219952,0.00038829484,0.000434423,0.000080578524,0.00030845325],"domain_scores_gemma":[0.9991572,0.000016578626,0.00012495363,0.00057075755,0.000024085104,0.000106443666],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000103870014,0.00032203735,0.00071330357,0.00023052537,0.000025510626,0.0000053092376,0.00031897216,0.0014485173,0.000019564257],"category_scores_gemma":[0.000058131533,0.00027700624,0.0002247251,0.00025470866,0.00033970125,8.1097517e-7,0.00034178531,0.00023160898,0.000012739187],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000023613136,0.00007202168,0.0000018846137,0.0013693996,0.00017396804,0.00000420597,0.000002068138,6.314243e-7,0.046799056,0.0006763759,0.00004289422,0.95085514],"study_design_scores_gemma":[0.0000969962,0.0001564719,0.0000018806148,0.00017073839,0.00022457665,0.00014504332,0.000004586317,0.0000016996134,0.018356007,0.000021980397,0.9805508,0.0002691981],"about_ca_topic_score_codex":0.0000015656879,"about_ca_topic_score_gemma":3.8035816e-7,"teacher_disagreement_score":0.9805079,"about_ca_system_score_codex":0.000007891275,"about_ca_system_score_gemma":0.000045178087,"threshold_uncertainty_score":0.99996823},"labels":[],"label_agreement":null},{"id":"W2036954783","doi":"10.1038/sj.leu.2403696","title":"Transplantable cell lines generated with NUP98–Hox fusion genes undergo leukemic progression by Meis1 independent of its binding to DNA","year":2005,"lang":"en","type":"article","venue":"Leukemia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; Terry Fox Foundation","keywords":"Hox gene; Fusion gene; Biology; Gene; DNA; Cancer research; Genetics; Cell fusion; Cell culture; Cell biology; Transcription factor","score_opus":0.006053653991817164,"score_gpt":0.25613171289350145,"score_spread":0.2500780589016843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036954783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856935,0.0032601634,0.010259016,0.00007199926,0.00008440661,0.00027757703,0.00003734761,0.00002723096,0.00028873945],"genre_scores_gemma":[0.9932519,0.0009559267,0.002882783,0.00007758995,0.00020687802,0.000028087872,0.0002359544,0.000043740813,0.0023171082],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879354,0.000023782106,0.0002607511,0.00038491498,0.00021226639,0.00032471816],"domain_scores_gemma":[0.99945796,0.0000071899553,0.00007506357,0.00025136958,0.00007333648,0.00013509448],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009814082,0.00023057174,0.00019455426,0.00007193613,0.00007098589,0.000030530406,0.00019349137,0.00019402064,0.00002217562],"category_scores_gemma":[0.000005723644,0.00019516064,0.000052270356,0.00016471633,0.000017006982,0.000011561192,0.000060454917,0.0001024655,0.000011718356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001329181,0.000038403872,0.00044845635,0.00008779336,0.000025015435,0.0000029886194,0.00007710255,0.021106686,0.97353673,0.0000029482464,0.0011707045,0.0033702664],"study_design_scores_gemma":[0.0009174616,0.0002908963,0.00018982908,0.000089947614,0.000031200812,0.00001956233,0.000053854274,0.0011573985,0.98149204,5.1275595e-7,0.015489616,0.00026769235],"about_ca_topic_score_codex":0.000024880283,"about_ca_topic_score_gemma":0.0000937333,"teacher_disagreement_score":0.019949287,"about_ca_system_score_codex":0.00011214033,"about_ca_system_score_gemma":0.00016877578,"threshold_uncertainty_score":0.795842},"labels":[],"label_agreement":null},{"id":"W2037072132","doi":"10.1038/nature14046","title":"Genome-wide characterization of the routes to pluripotency","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Reprogramming; Induced pluripotent stem cell; Chromatin; Biology; Epigenomics; Embryonic stem cell; Epigenetics; Somatic cell; DNA methylation; Histone; Cell biology; Genetics; Computational biology; Gene; Gene expression","score_opus":0.002128033207499291,"score_gpt":0.22967700082250952,"score_spread":0.22754896761501023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037072132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98939323,0.00016444975,0.009238402,0.00050346076,0.00018805184,0.000078044744,0.000007153131,0.0000042563956,0.0004229229],"genre_scores_gemma":[0.9984084,0.00001474159,0.00023441402,0.00067041046,0.00016017533,0.0000030343904,0.000030671687,0.0000074522236,0.00047074264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997015,0.000009974007,0.000062445586,0.00009761809,0.000057994945,0.00007047635],"domain_scores_gemma":[0.9997216,0.0000029055348,0.000020419515,0.00019669128,0.00003632471,0.000022097394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000046720957,0.000050540675,0.000046093606,0.000011961137,0.000018910328,0.000004180292,0.0001241962,0.00023550325,0.000005113977],"category_scores_gemma":[0.00009035477,0.000036841586,0.00003422205,0.000058253925,0.0000073987057,6.601245e-7,0.000050289036,0.00013989102,0.0000019891575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000037606753,0.000004362726,0.0027813318,0.0000072491002,0.0000049528526,2.6785413e-8,0.000027408823,0.00013833614,0.9961529,0.000029916571,0.00009926364,0.0007505381],"study_design_scores_gemma":[0.000054104425,0.000026504578,0.31492084,0.0000048623674,0.0000035488365,7.067088e-7,0.0000024742449,0.000023438324,0.59896475,0.000012236272,0.085941516,0.000045020435],"about_ca_topic_score_codex":7.275744e-7,"about_ca_topic_score_gemma":0.0000032345474,"teacher_disagreement_score":0.39718813,"about_ca_system_score_codex":0.0000023164016,"about_ca_system_score_gemma":0.000007620088,"threshold_uncertainty_score":0.18164167},"labels":[],"label_agreement":null},{"id":"W2037507104","doi":"10.1126/science.1177801","title":"Gene Doping and Sport","year":2010,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"World Anti-Doping Agency","funders":"","keywords":"Doping; Set (abstract data type); Computer science; Physics; Optoelectronics","score_opus":0.003849913163863997,"score_gpt":0.2827619800666494,"score_spread":0.27891206690278536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037507104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975481,0.0001460952,0.0012774073,0.00003063746,0.00020099521,0.000023336304,4.5551496e-7,0.000004670112,0.00076827424],"genre_scores_gemma":[0.9959702,0.00002497009,0.0037513191,0.00004766518,0.000088359855,0.0000012055079,9.860531e-7,0.0000024477222,0.00011285231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996537,4.725354e-7,0.000034526383,0.00014861116,0.000056445413,0.00010624688],"domain_scores_gemma":[0.99979335,6.612699e-7,0.000006692225,0.00013023353,0.000018097682,0.000050949042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012763875,0.000032779488,0.00002409231,0.000017367625,0.00005557438,0.000017103708,0.00009352688,0.00002016822,0.0000040078276],"category_scores_gemma":[0.000021854552,0.000030246822,0.0000072629387,0.000058813257,0.00013663307,0.0000016600364,0.00006266984,0.00003365948,0.0000019626666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[6.27933e-7,0.0000014393938,0.0052246745,0.0000011133591,4.0701002e-7,3.8816285e-7,0.0000099057725,0.000010831275,0.9921394,0.000051008756,0.000009229322,0.0025509691],"study_design_scores_gemma":[0.00004492112,0.000014884088,0.047800288,8.7909586e-7,8.070901e-7,0.000023086683,0.000007987029,0.000100228914,0.94175667,0.000022252103,0.010177333,0.00005065743],"about_ca_topic_score_codex":0.0000020946102,"about_ca_topic_score_gemma":0.000007779172,"teacher_disagreement_score":0.05038273,"about_ca_system_score_codex":8.4976983e-7,"about_ca_system_score_gemma":0.000028510183,"threshold_uncertainty_score":0.12334295},"labels":[],"label_agreement":null},{"id":"W2037524213","doi":"10.1016/j.tcb.2014.04.006","title":"Inherited small RNAs: new insights into Darwin's cell theory","year":2014,"lang":"en","type":"letter","venue":"Trends in Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; Transgenerational epigenetics; Scopus; Variation (astronomy); Evolutionary biology; Darwin (ADL); Inheritance (genetic algorithm); Genetics; Computational biology; MEDLINE; Epigenetics; Gene; Computer science","score_opus":0.013697899286028447,"score_gpt":0.2889436636122798,"score_spread":0.27524576432625136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037524213","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20666559,0.13204223,0.1026235,0.13892339,0.01452505,0.0020464296,0.00021502914,0.00069202104,0.40226674],"genre_scores_gemma":[0.47723892,0.0035342814,0.00787592,0.38615,0.020343816,0.00015325347,0.017347544,0.00061272486,0.08674353],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99753517,0.00028808022,0.00048112264,0.00097331306,0.00008499618,0.0006373217],"domain_scores_gemma":[0.9987165,0.000070694456,0.00016030639,0.00090364565,0.000037277943,0.00011158348],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00018231534,0.0005915158,0.0005535908,0.00041434792,0.00004522557,0.000022297923,0.0006766806,0.0022222465,0.00025924123],"category_scores_gemma":[0.00002673258,0.00055644254,0.00022435209,0.0002240074,0.00013552733,0.0000015621821,0.0002672288,0.0010728757,0.000056173452],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000633559,0.000055213128,0.00012267826,0.00015170132,0.00006502381,0.00007350819,0.00024355848,0.00018891826,0.33761823,0.000020149753,0.6280861,0.03331156],"study_design_scores_gemma":[0.0007623261,0.00034709266,0.000052294636,0.000019460946,0.00003584417,0.0000075228427,0.000013640675,0.000030756164,0.10278915,0.00044593328,0.8948932,0.0006027298],"about_ca_topic_score_codex":0.00015034135,"about_ca_topic_score_gemma":0.00017277588,"teacher_disagreement_score":0.3155232,"about_ca_system_score_codex":0.000033550947,"about_ca_system_score_gemma":0.000086057364,"threshold_uncertainty_score":0.9996887},"labels":[],"label_agreement":null},{"id":"W2037628829","doi":"10.1093/nar/gkv118","title":"Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Biology; Extrachromosomal DNA; RAD51; Amplicon; Genetics; Recombinase; Leishmania infantum; Homologous recombination; Gene; Genome; Computational biology; Recombination; Polymerase chain reaction; Visceral leishmaniasis; Leishmaniasis","score_opus":0.03591258163773044,"score_gpt":0.37373332232861917,"score_spread":0.33782074069088874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037628829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963755,0.00055766007,0.0015076166,0.00017250853,0.00007130927,0.00036135432,0.000006444762,0.000008200968,0.0009393867],"genre_scores_gemma":[0.9979738,0.000058314814,0.0015367938,0.000008005091,0.00007853275,0.00005830065,0.00004171647,0.000020403759,0.00022410724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989646,0.00008113065,0.00020323697,0.00023422684,0.00020287528,0.0003139178],"domain_scores_gemma":[0.9993871,0.0000327437,0.00003111345,0.0002256627,0.0002508336,0.00007258501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012872712,0.000080467886,0.0001272081,0.00013495785,0.000035590612,0.000014857554,0.00020907653,0.0001356803,0.000004719837],"category_scores_gemma":[0.00063273706,0.00008169822,0.00003932674,0.00017593216,0.00007350104,0.0000045003057,0.00012257221,0.00013624769,0.0000035085666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002347141,0.00019306738,0.019421767,0.00015832421,0.000030515772,0.0000054548373,0.0012669407,0.0005346746,0.9408834,0.00048640746,0.0029499487,0.033834774],"study_design_scores_gemma":[0.002707355,0.002012997,0.01609788,0.00007198426,0.000006922329,0.000021378437,0.0010408543,0.0072584148,0.9516624,0.0033548805,0.015476675,0.00028823552],"about_ca_topic_score_codex":0.00003099858,"about_ca_topic_score_gemma":0.0000692672,"teacher_disagreement_score":0.03354654,"about_ca_system_score_codex":0.000027980006,"about_ca_system_score_gemma":0.0000916423,"threshold_uncertainty_score":0.3331557},"labels":[],"label_agreement":null},{"id":"W2038591876","doi":"10.1038/nprot.2007.13","title":"High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method","year":2007,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2955,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transformation (genetics); Transformation efficiency; Yeast; Saccharomyces cerevisiae; PEG ratio; Yield (engineering); DNA; Lithium (medication); Computational biology; Chemistry; Combinatorial chemistry; Biology; Biochemistry; Materials science; Gene; Agrobacterium","score_opus":0.010319084552111574,"score_gpt":0.3798412857771429,"score_spread":0.3695222012250313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038591876","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.081882134,0.0002919158,0.89051205,0.0001391409,0.0003327321,0.025737282,0.000026674828,0.00003194026,0.0010461408],"genre_scores_gemma":[0.98034453,0.0000031164686,0.014297953,0.00026788542,0.00055776583,0.00425625,0.0000291227,0.000029974242,0.00021340027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912816,0.0000352109,0.0001956311,0.00020584781,0.0001772463,0.00025792368],"domain_scores_gemma":[0.99952376,0.000011219911,0.000047973022,0.00027999879,0.0000795903,0.00005744441],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059353985,0.00014020778,0.00010243111,0.00003693205,0.00010904831,0.00003139278,0.0002011786,0.00032442887,0.000010796326],"category_scores_gemma":[0.000046186855,0.000101741316,0.00007965923,0.00015108155,0.00002670846,0.0000044647195,0.000032721182,0.0002897821,0.0000017092566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007050154,0.000028503971,0.0000720126,0.000046674173,0.000021237447,0.0000022599975,0.00021941056,0.0022740385,0.98859733,0.00048465238,0.0002542085,0.007929156],"study_design_scores_gemma":[0.00040126342,0.00008671406,0.0006528438,0.000024616387,0.000013153244,0.000023257155,0.000082719685,0.0007210002,0.8993797,0.000047874557,0.09841193,0.0001549839],"about_ca_topic_score_codex":0.0000094073785,"about_ca_topic_score_gemma":0.000018973427,"teacher_disagreement_score":0.8984624,"about_ca_system_score_codex":0.00001717807,"about_ca_system_score_gemma":0.00004177776,"threshold_uncertainty_score":0.41488904},"labels":[],"label_agreement":null},{"id":"W2038743372","doi":"10.1186/gm392","title":"Designing a post-genomics knowledge ecosystem to translate pharmacogenomics into public health action","year":2012,"lang":"en","type":"article","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Pharmacogenomics; Action (physics); Corporate governance; Order (exchange); Knowledge management; Knowledge translation; Public relations; Sociology of scientific knowledge; Business; Political science; Sociology; Computer science; Social science; Bioinformatics; Biology","score_opus":0.038996043020684726,"score_gpt":0.3645750948087091,"score_spread":0.3255790517880244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038743372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7354978,0.018235344,0.24183074,0.002509402,0.0010062159,0.0004831507,0.000019152723,0.000041908865,0.0003763348],"genre_scores_gemma":[0.9925679,0.0006941473,0.0034701782,0.0008984171,0.0019882142,0.000034479923,0.00016526692,0.000053532945,0.00012784405],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985822,0.00007363085,0.00034738315,0.00029299574,0.000102749014,0.0006010715],"domain_scores_gemma":[0.9989637,0.000012067376,0.00006933418,0.00028056643,0.000085062806,0.0005892279],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086141285,0.00021867803,0.0002561837,0.00015229268,0.000125467,0.000012269528,0.00019466138,0.00009002287,0.00004331033],"category_scores_gemma":[0.00003950713,0.00020932035,0.00006232285,0.00017184255,0.000023610673,0.0000068629447,0.000064475695,0.00011056326,0.00006128175],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027773505,0.000038620186,0.00015132662,0.00010305772,0.00007240887,5.3630066e-7,0.00493807,0.00025812,0.96613204,0.000009595155,0.00039937356,0.02786909],"study_design_scores_gemma":[0.0011599183,0.0007737803,0.0013571111,0.00003520547,0.00004958656,0.00007981571,0.0015727336,0.00014308104,0.16815457,0.000005311769,0.82624245,0.00042644152],"about_ca_topic_score_codex":0.000026482116,"about_ca_topic_score_gemma":0.00010816671,"teacher_disagreement_score":0.8258431,"about_ca_system_score_codex":0.00013141111,"about_ca_system_score_gemma":0.00013449325,"threshold_uncertainty_score":0.8535836},"labels":[],"label_agreement":null},{"id":"W2038886726","doi":"10.1073/pnas.1107719108","title":"Tapping natural reservoirs of homing endonucleases for targeted gene modification","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research","keywords":"Homing endonuclease; Biology; Genome; Gene; DNA; Computational biology; Genetics; Homing (biology); Endonuclease; Phylogenetic tree","score_opus":0.05112018559372235,"score_gpt":0.3278944863519599,"score_spread":0.27677430075823756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038886726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99861985,0.0005013181,0.00009766558,0.000107214946,0.000018851895,0.00012956871,0.000013609619,0.0000026650478,0.0005092346],"genre_scores_gemma":[0.98974776,0.000032352295,0.010100257,0.00002401092,0.000048063845,0.00000854065,6.901758e-7,0.0000033241352,0.00003500467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993569,0.0000018894116,0.00018743584,0.00013770364,0.00023086442,0.00008520894],"domain_scores_gemma":[0.99955505,0.000015700525,0.00019199152,0.000008402806,0.00021473973,0.000014085348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037883746,0.00005206639,0.00007357367,0.000058265836,0.00006146201,0.0000034569293,0.00035021064,0.00004739466,0.0000016169254],"category_scores_gemma":[0.00035741678,0.00003943758,0.000060692408,0.00015877058,0.00020164509,0.0000123289665,0.00006547971,0.00003543523,4.832699e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021495718,0.0000131325405,0.00076225854,0.00004375826,0.000011501632,3.4709144e-10,0.00009120241,0.00019669882,0.9968267,0.0017534804,0.000099449135,0.00018028892],"study_design_scores_gemma":[0.00010880935,0.00004253009,0.019705655,0.000022286333,0.000007122776,0.0000014423172,0.00011823597,0.0014914109,0.97659284,0.0017800824,0.000084931,0.000044656193],"about_ca_topic_score_codex":0.0000035845312,"about_ca_topic_score_gemma":4.8539917e-8,"teacher_disagreement_score":0.020233896,"about_ca_system_score_codex":0.000004499971,"about_ca_system_score_gemma":0.000013898512,"threshold_uncertainty_score":0.16082178},"labels":[],"label_agreement":null},{"id":"W2039269481","doi":"10.1007/s00335-008-9114-0","title":"Chemical mutagenesis: a new strategy against the global threat of infectious diseases","year":2008,"lang":"en","type":"review","venue":"Mammalian Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal General Hospital; McGill Genome Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Biology; Genome; Mutagenesis; Infectious disease (medical specialty); Pandemic; Virus; Virulence; Disease; Gene; Virology; Genetics; Mutation; Coronavirus disease 2019 (COVID-19); Medicine","score_opus":0.01566355418184792,"score_gpt":0.30531049145861955,"score_spread":0.28964693727677165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039269481","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014900207,0.9964464,0.00041417993,0.000007239534,0.00013440748,0.0004037786,0.0002487626,0.000022470163,0.00083275366],"genre_scores_gemma":[0.005173709,0.9929124,0.000044855617,0.000030004672,0.00074930605,0.000042802236,0.0005010526,0.00005331805,0.0004925627],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985872,0.00005207932,0.00043287876,0.0004423821,0.00015327962,0.000332208],"domain_scores_gemma":[0.9989478,0.000011220253,0.00016067647,0.00066426385,0.000036733953,0.00017928543],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000038610844,0.0004298646,0.00072184426,0.000035308938,0.000052098898,0.00002319629,0.00046498305,0.00032289914,0.00003079485],"category_scores_gemma":[0.000027005288,0.0003172465,0.0006030532,0.00020604442,0.00010157368,0.000001552514,0.00018265427,0.00012474546,0.00002782016],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001745655,0.000097459146,0.0001331676,0.003526736,0.00067656965,0.00005115628,0.000030517325,0.0005251094,0.0013302453,0.000043455522,0.0015806274,0.9919875],"study_design_scores_gemma":[0.00022282716,0.000081644714,0.000095190284,0.00026211617,0.00033917837,0.00019888004,0.000010745599,0.0000016069805,0.0002376274,0.000018392178,0.99811995,0.00041183064],"about_ca_topic_score_codex":0.000026135578,"about_ca_topic_score_gemma":0.0000105580275,"teacher_disagreement_score":0.99653935,"about_ca_system_score_codex":0.000052140414,"about_ca_system_score_gemma":0.00038875654,"threshold_uncertainty_score":0.99992794},"labels":[],"label_agreement":null},{"id":"W2039591253","doi":"10.1182/blood-2002-07-2086","title":"LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of β-globin intron-2","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Locus control region; Transgene; Molecular biology; Biology; Intron; Globin; Mutant; Ectopic expression; Regulatory sequence; Binding site; Transcription (linguistics); Gene; Promoter; Gene expression; Genetics","score_opus":0.012848861019465307,"score_gpt":0.25531812775685525,"score_spread":0.24246926673738994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039591253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711484,0.0008110361,0.0009937085,0.00014423636,0.000040055715,0.00018404963,0.000006997398,0.000004294509,0.0007007702],"genre_scores_gemma":[0.9995328,0.00006122636,0.00012305772,0.000089342786,0.000039152575,0.000015359277,0.000014815073,0.000012173095,0.00011205894],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928576,0.00010248529,0.00015568951,0.00018274452,0.00011339448,0.00015992174],"domain_scores_gemma":[0.99952793,0.000027432276,0.000037566642,0.00036603608,0.000019321376,0.000021706543],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002001887,0.000111832436,0.0000924046,0.000023588125,0.00004498709,0.0000066601992,0.00015575124,0.000097193035,0.000016455899],"category_scores_gemma":[0.000043309814,0.00006844338,0.000053697637,0.00010203053,0.00002393605,0.0000011944244,0.000022322734,0.00007829983,0.0000029225223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024450028,0.00010864188,0.0007054607,0.000008991969,0.00001585896,0.0000042604447,0.0002313753,0.00078238425,0.9975714,0.00006722386,0.000320634,0.0001593223],"study_design_scores_gemma":[0.0007665944,0.00012190456,0.004556814,0.000020683196,0.000018742414,0.00003005199,0.00006699312,0.00001845437,0.9908232,0.000026541502,0.003459794,0.00009024671],"about_ca_topic_score_codex":0.000005205832,"about_ca_topic_score_gemma":0.000037584927,"teacher_disagreement_score":0.0067482167,"about_ca_system_score_codex":0.0000046070204,"about_ca_system_score_gemma":0.000014154768,"threshold_uncertainty_score":0.27910402},"labels":[],"label_agreement":null},{"id":"W2039623374","doi":"10.1038/nsmb.1972","title":"An assessment of histone-modification antibody quality","year":2010,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":444,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute of Environmental Health Sciences; National Human Genome Research Institute; National Institutes of Health; Wellcome Trust","keywords":"Antibody; Histone; Chromatin immunoprecipitation; Western blot; Dot blot; Caenorhabditis elegans; Immunoprecipitation; Drosophila melanogaster; Chromatin; Molecular biology; Cell biology; Histone H2A; Biology; Chemistry; Genetics; Gene; Gene expression; Promoter","score_opus":0.005846044760050905,"score_gpt":0.49954257680829545,"score_spread":0.49369653204824454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039623374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9579838,0.00046988644,0.040269826,0.000110087414,0.0006323709,0.000150901,0.000042008032,0.00001802314,0.00032309594],"genre_scores_gemma":[0.98591906,0.000014245963,0.012726845,0.00015270658,0.00016595933,0.000006722639,0.0009789385,0.000019116473,0.000016414346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988906,0.00008899237,0.000270429,0.0004223767,0.00010580568,0.00022183276],"domain_scores_gemma":[0.99900746,0.0000068009226,0.00012309832,0.00062885956,0.00015004464,0.00008372584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001887857,0.00018316148,0.00020434342,0.000058036443,0.000046856912,0.000009014366,0.0003120243,0.00063724275,0.000025161664],"category_scores_gemma":[0.00008139162,0.00016413162,0.000106634136,0.00008631798,0.00013288838,0.000003507961,0.000058826958,0.00045866048,5.487011e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017124097,0.000015228703,0.00491145,0.000014017608,0.0000311182,9.2058815e-7,0.000010090603,0.00010921304,0.97984695,0.012951851,0.000015105844,0.002076955],"study_design_scores_gemma":[0.00030250693,0.00020386663,0.14703402,0.0000018849767,0.000015401798,0.000018904067,0.000010981681,0.00036460263,0.8495335,0.0006845605,0.001620222,0.0002095211],"about_ca_topic_score_codex":0.000030505902,"about_ca_topic_score_gemma":0.000028428269,"teacher_disagreement_score":0.14212257,"about_ca_system_score_codex":0.000008729087,"about_ca_system_score_gemma":0.000059813738,"threshold_uncertainty_score":0.6693093},"labels":[],"label_agreement":null},{"id":"W2040527067","doi":"10.1073/pnas.1014660108","title":"Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia; Michael Smith Health Research BC","keywords":"DNA methylation; Methylation; Gene silencing; Biology; Methyltransferase; Endogenous retrovirus; Retrovirus; Murine leukemia virus; Histone H3; Molecular biology; DNA; Genetics; Gene; Gene expression; Genome","score_opus":0.032359983135472885,"score_gpt":0.308680346199615,"score_spread":0.2763203630641421,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040527067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996705,0.0002565532,0.00066084974,0.0014816661,0.000012576402,0.00027570906,0.000022303906,0.0000019227425,0.0005834277],"genre_scores_gemma":[0.9967257,0.00009047791,0.002827251,0.00021495983,0.00004471457,0.000021229716,2.4570224e-7,0.000003295227,0.000072133764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926895,0.0000070116193,0.00021058478,0.00014390859,0.00026077923,0.00010879413],"domain_scores_gemma":[0.99956393,0.000064065505,0.0001592203,0.000013596687,0.00018440513,0.000014766342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015892042,0.00006543771,0.00009645476,0.00003811439,0.00010689227,0.000009821777,0.00035423215,0.000050761886,0.0000016529647],"category_scores_gemma":[0.00045642653,0.00003323018,0.00006715586,0.00017390927,0.00059864187,0.000019095034,0.000060690905,0.00005105038,2.3525516e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008559709,0.00000943251,0.00030626697,0.00004265224,0.000020475356,8.120787e-10,0.00055543927,0.00004605395,0.9922024,0.0061493265,0.00007276028,0.00050957635],"study_design_scores_gemma":[0.00036983792,0.000059775022,0.003999658,0.000019931136,0.000025148738,0.0000032375874,0.00037206107,0.0011430115,0.98741424,0.006465198,0.00008516534,0.000042762385],"about_ca_topic_score_codex":0.000012515179,"about_ca_topic_score_gemma":2.3220727e-7,"teacher_disagreement_score":0.0047882055,"about_ca_system_score_codex":0.0000056731074,"about_ca_system_score_gemma":0.000026320718,"threshold_uncertainty_score":0.2205721},"labels":[],"label_agreement":null},{"id":"W2040575854","doi":"10.2174/156652309787354667","title":"A Possible Approach for Stem Cell Gene Therapy of Fanconi Anemia","year":2009,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Fanconi anemia; Genetic enhancement; Gene; Stem cell; Anemia; Medicine; Cancer research; Genetics; Biology; Computational biology; Bioinformatics; DNA repair; Internal medicine","score_opus":0.052818245779552055,"score_gpt":0.3684791430286231,"score_spread":0.31566089724907104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040575854","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001080294,0.9735256,0.02307139,0.0000019546446,0.00041008595,0.001589038,0.00018351141,0.000022538085,0.000115621944],"genre_scores_gemma":[0.000277845,0.9941744,0.0028093364,0.000018674993,0.0007879208,0.00028884385,0.0012878494,0.00011248571,0.00024261804],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99800056,0.000075691365,0.0006227113,0.0006956179,0.00016793043,0.00043751113],"domain_scores_gemma":[0.9986351,0.00001771252,0.00032628837,0.0008035082,0.00010294737,0.00011442469],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022237783,0.00061421865,0.0011300968,0.00011606486,0.000057435496,0.000026683227,0.00054843357,0.0004030461,0.000008166669],"category_scores_gemma":[0.0000024010096,0.00050753896,0.0008184789,0.00017264564,0.000036675105,0.0000023761204,0.000046915993,0.00018852671,0.0000024081849],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051436793,0.0002283961,0.000001997493,0.0022493058,0.00012588274,3.0345737e-7,0.00003879296,0.00007767337,0.023713382,0.0000035212724,0.0008042541,0.97270507],"study_design_scores_gemma":[0.0009668639,0.00053869514,0.0000022699837,0.00026488752,0.00007035021,0.000011949754,0.000006401373,0.000022430535,0.14699319,0.0000063110815,0.8506043,0.00051234994],"about_ca_topic_score_codex":0.0000011674227,"about_ca_topic_score_gemma":2.0296626e-7,"teacher_disagreement_score":0.9721927,"about_ca_system_score_codex":0.000024772618,"about_ca_system_score_gemma":0.00025140413,"threshold_uncertainty_score":0.9997376},"labels":[],"label_agreement":null},{"id":"W2040833436","doi":"10.1126/science.1194006","title":"Regulating Direct-to-Consumer Personal Genome Testing","year":2010,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Health Economics","funders":"National Human Genome Research Institute","keywords":"Personal genomics; Genome; Computational biology; Genetic testing; Biology; Business; Genetics; Genomics; Gene","score_opus":0.00934836039390705,"score_gpt":0.2896105275370234,"score_spread":0.2802621671431163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040833436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99322826,0.000086977816,0.0013048241,0.000041997813,0.00024031116,0.00005453122,0.0000022763807,0.000014972402,0.0050258324],"genre_scores_gemma":[0.9849274,0.000001075913,0.014389815,0.00008201497,0.00017696152,0.000004533299,0.0000014673357,0.0000070908004,0.00040963612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992689,0.0000031477823,0.00007090402,0.00028542464,0.00013050059,0.00024111324],"domain_scores_gemma":[0.9996017,0.000008255846,0.000015311709,0.00018771878,0.00007130229,0.00011567019],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028594193,0.00006658176,0.000045616925,0.000041696698,0.00014872522,0.000036894973,0.00020303502,0.000030365762,0.000011125119],"category_scores_gemma":[0.00044553066,0.000064331805,0.000018141383,0.00025119763,0.00012688148,0.0000028969343,0.00011653918,0.00006683001,0.000016740485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000011647177,0.0000031159275,0.0032371886,0.0000019106249,0.0000010486506,3.506343e-7,0.00006579797,0.00017342185,0.99185663,0.0000058372248,0.000017358327,0.0046362006],"study_design_scores_gemma":[0.00008293641,0.000051915915,0.08803177,0.000005339222,0.000002838254,0.000024915831,0.000041231204,0.0016473911,0.89250606,0.000009925213,0.017413352,0.00018234234],"about_ca_topic_score_codex":0.0000059777694,"about_ca_topic_score_gemma":0.00001420963,"teacher_disagreement_score":0.09935056,"about_ca_system_score_codex":0.000004440305,"about_ca_system_score_gemma":0.00007227891,"threshold_uncertainty_score":0.26233748},"labels":[],"label_agreement":null},{"id":"W2040891039","doi":"10.1038/nature08858","title":"Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":822,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology; Michael Smith Health Research BC","keywords":"Endogenous retrovirus; Biology; DNA methylation; Histone methylation; Histone methyltransferase; Histone; Embryonic stem cell; Epigenetics; Cell biology; Molecular biology; Genetics; DNA; Genome; Gene","score_opus":0.00401127184698153,"score_gpt":0.28649735243059865,"score_spread":0.2824860805836171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040891039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99537563,0.0026909467,0.00034562618,0.00042291186,0.00060848356,0.00016040514,0.000012174802,0.0000118812095,0.00037196523],"genre_scores_gemma":[0.9984258,0.00006120029,0.0002788496,0.00028295672,0.0002319484,0.000014467946,0.000013836262,0.000017167748,0.00067378196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993439,0.000024012475,0.000108061155,0.00022213571,0.00010177744,0.00020011252],"domain_scores_gemma":[0.9995851,0.000014538277,0.000017842138,0.0003179241,0.000025729096,0.000038897633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019793169,0.00011606139,0.000087894674,0.000030208623,0.000042714826,0.000015702071,0.00021638612,0.00064429216,0.000011828155],"category_scores_gemma":[0.000021254531,0.00008540609,0.00005811647,0.0000644638,0.00003792587,0.0000025047318,0.000038887538,0.0012790713,0.0000037690197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001886096,0.000012927706,0.00012361995,0.00001612748,0.00000792919,0.0000042936963,0.00008897213,0.00020142931,0.9958733,0.00008748896,0.001118246,0.002446806],"study_design_scores_gemma":[0.00023897813,0.000056430796,0.00075304025,0.000007338981,0.000007867692,0.000009125142,0.00007686944,0.00011856131,0.97282535,0.000017394552,0.025764572,0.00012445802],"about_ca_topic_score_codex":0.000017398908,"about_ca_topic_score_gemma":0.00036582781,"teacher_disagreement_score":0.024646327,"about_ca_system_score_codex":0.0000092963355,"about_ca_system_score_gemma":0.000044704808,"threshold_uncertainty_score":0.55569994},"labels":[],"label_agreement":null},{"id":"W2041557174","doi":"10.1021/jf800137q","title":"Detection of Genetically Modified Canola Using Multiplex PCR Coupled with Oligonucleotide Microarray Hybridization","year":2008,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Canola; Amplicon; Oligonucleotide; Biology; Multiplex; Transgene; Genetically modified crops; Molecular biology; Multiplex polymerase chain reaction; Gene; Computational biology; Genetics; Polymerase chain reaction; Botany","score_opus":0.008266762713085893,"score_gpt":0.21217016820576864,"score_spread":0.20390340549268277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041557174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926256,0.0011568196,0.006086387,0.000012627212,0.000032344844,0.000044827175,0.000004380979,0.000003018705,0.000034025576],"genre_scores_gemma":[0.99784094,0.00031097076,0.0016065016,0.0000061926767,0.0001909661,6.798696e-7,0.000008282778,0.000008150393,0.00002730448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939793,0.000007018858,0.0002511637,0.00011404299,0.000115513416,0.000114335126],"domain_scores_gemma":[0.99944425,0.0000048974794,0.00017964448,0.00006893488,0.00022165115,0.0000806555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000380271,0.00011935607,0.00015626675,0.000013888327,0.000056737284,0.000008212549,0.00006681832,0.00008147904,0.0000016170526],"category_scores_gemma":[0.000020090652,0.00007915019,0.000063058804,0.00006368829,0.00005806198,0.0000057399725,0.00002145428,0.000085188505,4.594598e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005897968,0.000025917157,0.0004823427,0.000042555163,0.000076239216,0.000002015661,0.000043682605,0.00994646,0.9891694,1.370182e-7,0.000009174594,0.00014308577],"study_design_scores_gemma":[0.0006584169,0.00028699607,0.025039397,0.000031639152,0.00004360529,0.0013526179,0.000115737734,0.0004596857,0.9718528,9.0096114e-7,0.000036165588,0.0001220813],"about_ca_topic_score_codex":0.0000067124606,"about_ca_topic_score_gemma":0.000005772232,"teacher_disagreement_score":0.024557054,"about_ca_system_score_codex":0.000011890754,"about_ca_system_score_gemma":0.000032096457,"threshold_uncertainty_score":0.3227651},"labels":[],"label_agreement":null},{"id":"W2041607260","doi":"10.1182/blood-2013-04-497354","title":"Robust ZFN-mediated genome editing in adult hemophilic mice","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Zinc finger nuclease; Genome editing; Biology; Zinc finger; Genetic enhancement; Genome; Gene; Computational biology; Transcription activator-like effector nuclease; DNA; Genetics; Cell biology; Virology; Transcription factor","score_opus":0.005392661695598176,"score_gpt":0.2157135006048714,"score_spread":0.21032083890927322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041607260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975386,0.000645767,0.0004892784,0.00013167634,0.00008692387,0.00014430041,0.0000069542834,0.000017298058,0.0009391555],"genre_scores_gemma":[0.997933,0.00009291204,0.0010570093,0.00020078679,0.00042623378,0.00003583624,0.0000900916,0.000020560126,0.00014359456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992994,0.000012123287,0.00015331435,0.00022309365,0.00006637186,0.0002456906],"domain_scores_gemma":[0.9996721,0.0000074921236,0.000025649459,0.00017734036,0.00005078863,0.00006663109],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051278264,0.00011022581,0.000091948365,0.000039119506,0.00002204967,0.000016814796,0.00011993645,0.000102522135,0.000040434013],"category_scores_gemma":[0.00008843781,0.00011483434,0.0000371063,0.00008515095,0.00001661145,0.0000025348945,0.000059776576,0.00007955058,0.000059154638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000018925381,0.00007440791,0.0037066909,0.000019608766,0.00001812675,0.0000041971807,0.000044244767,0.0007219663,0.9949499,0.0000031208888,0.00023482346,0.00022107168],"study_design_scores_gemma":[0.0037432727,0.00025438395,0.09514868,0.000049826376,0.000043396576,0.00007532131,0.00038672902,0.001430361,0.89258623,0.000033762484,0.0055355057,0.00071252545],"about_ca_topic_score_codex":0.00006286087,"about_ca_topic_score_gemma":0.00005202418,"teacher_disagreement_score":0.102363616,"about_ca_system_score_codex":0.0000043714554,"about_ca_system_score_gemma":0.000014463661,"threshold_uncertainty_score":0.46828085},"labels":[],"label_agreement":null},{"id":"W2041801904","doi":"10.1038/sj.gt.3302074","title":"Illegitimate DNA integration in mammalian cells","year":2003,"lang":"en","type":"review","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University; Université de Montréal","funders":"","keywords":"Biology; Genome; Genetics; DNA; Computational biology; Locus (genetics); Gene; Genome instability; DNA damage","score_opus":0.02180882947428856,"score_gpt":0.3355680229535563,"score_spread":0.31375919347926773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041801904","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004249283,0.99679625,0.0014390319,0.000004175718,0.00035833832,0.00043540564,0.00002560704,0.00001010319,0.000506182],"genre_scores_gemma":[0.00008751891,0.9976762,0.0007394886,0.00006169924,0.00020921307,0.00009253104,0.00032865547,0.00006527208,0.000739441],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989148,0.00007921781,0.00031683123,0.00036224208,0.000075702694,0.00025120037],"domain_scores_gemma":[0.9994475,0.0000052970904,0.00007873959,0.0003977036,0.000020307189,0.00005044368],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014972145,0.00031743073,0.00048570771,0.00009325184,0.000021612115,0.000022053124,0.00018690997,0.00030658933,0.00004846328],"category_scores_gemma":[0.000004197032,0.00027414036,0.00022497587,0.00012657342,0.000018547162,0.0000011713939,0.000024456966,0.00013217289,0.000032430882],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062542013,0.0000251631,4.1260267e-7,0.000305998,0.000036130397,0.0000047490266,0.000019588475,0.00003059824,0.02782169,0.000007513058,0.0006868317,0.9710551],"study_design_scores_gemma":[0.00020525018,0.000078637786,0.000001340609,0.00029084997,0.00001862926,0.000017643128,0.0000055496616,0.0000027121755,0.054492183,0.0000076038414,0.9445889,0.0002907187],"about_ca_topic_score_codex":0.0000055714513,"about_ca_topic_score_gemma":0.000011528663,"teacher_disagreement_score":0.97076434,"about_ca_system_score_codex":0.000022744747,"about_ca_system_score_gemma":0.000070119284,"threshold_uncertainty_score":0.9999711},"labels":[],"label_agreement":null},{"id":"W2041981863","doi":"10.1016/j.mrfmmm.2010.12.013","title":"Abiotic stress leads to somatic and heritable changes in homologous recombination frequency, point mutation frequency and microsatellite stability in Arabidopsis plants","year":2011,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Human Frontier Science Program; Alberta Agricultural Research Institute","keywords":"Homologous recombination; Biology; Genetics; Arabidopsis; Abiotic stress; Transgene; Homologous chromosome; Recombination; Mutation; Point mutation; Ectopic recombination; Genetic recombination; Mutant; Gene","score_opus":0.026419207628503045,"score_gpt":0.29974689753464673,"score_spread":0.2733276899061437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041981863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99439293,0.0013437476,0.0033917956,0.00011657538,0.00003793358,0.0005993827,0.000060797516,0.0000074870763,0.000049342267],"genre_scores_gemma":[0.9937378,0.0003444575,0.0056746467,0.00004137194,0.0000047008775,0.000080542835,0.00008825847,0.000017699958,0.00001047941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858516,0.00018383747,0.00028602904,0.00044339884,0.00019702932,0.00030453515],"domain_scores_gemma":[0.9995613,0.000030380179,0.000055164623,0.00016850152,0.00007271345,0.00011195855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006677279,0.00016325993,0.00019966323,0.0003081669,0.00006080919,0.00003124209,0.00008756718,0.00012558099,0.000023443405],"category_scores_gemma":[0.00008669751,0.0001781682,0.00002256114,0.00019233239,0.00010044412,0.000017332724,0.0001146888,0.00009211444,0.0000010535624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005112107,0.00013511408,0.0076255915,0.00023183532,0.00001669028,0.0000519744,0.0019105349,0.00002290644,0.9839961,0.00013141012,6.799642e-7,0.0058260323],"study_design_scores_gemma":[0.0006105187,0.00068976043,0.053831205,0.00008168918,0.0000089074265,0.000030605195,0.0023684576,0.00015305763,0.9380035,0.0040559904,0.0000011139739,0.00016523933],"about_ca_topic_score_codex":0.0007999025,"about_ca_topic_score_gemma":0.0013834045,"teacher_disagreement_score":0.046205614,"about_ca_system_score_codex":0.000045897938,"about_ca_system_score_gemma":0.000031465042,"threshold_uncertainty_score":0.7265488},"labels":[],"label_agreement":null},{"id":"W2042183771","doi":"10.1038/mtm.2013.5","title":"Targeted CNS delivery using human MiniPromoters and demonstrated compatibility with adeno-associated viral vectors","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Child and Family Research Institute; University of British Columbia","funders":"National Institute of General Medical Sciences; National Eye Institute; National Institutes of Health; Genome British Columbia; Research to Prevent Blindness; Child and Family Research Institute; Michael Smith Health Research BC; Macula Vision Research Foundation; GlaxoSmithKline; Canadian Institutes of Health Research; Genome Canada","keywords":"Biology; Adeno-associated virus; Gene; Gene expression; Reporter gene; Viral vector; Genetic enhancement; Vectors in gene therapy; Locus (genetics); Genetics; Neuroscience; Vector (molecular biology)","score_opus":0.04121332399426751,"score_gpt":0.4150032049627303,"score_spread":0.3737898809684628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042183771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.74818414,0.00046817213,0.25092292,0.000020952257,0.00009535076,0.0002391083,0.0000021982178,0.000029138982,0.00003802162],"genre_scores_gemma":[0.74525005,0.000046633577,0.25428987,0.00024077752,0.00003334966,0.000010780324,0.00007084854,0.00003816352,0.000019548179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99718356,0.00091703836,0.0006497106,0.0006761853,0.00018995724,0.00038355857],"domain_scores_gemma":[0.9990486,0.00008801197,0.00016001174,0.00037404423,0.00012159067,0.00020776968],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018770036,0.00032645778,0.00043220163,0.00005331768,0.00015940353,0.000039855993,0.00019202597,0.00027528836,0.00001097791],"category_scores_gemma":[0.00018914952,0.00028718056,0.00011562208,0.00013494461,0.00018111845,0.00000446535,0.00009963718,0.00022374898,0.0000010931185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014078201,0.0001850601,0.021622688,0.000013033802,0.00047245558,0.000006255551,0.00010932457,0.00029632592,0.92848843,0.000008236935,0.00001024276,0.048647147],"study_design_scores_gemma":[0.0026822577,0.001056696,0.17591603,0.000052472773,0.00007007731,0.000010294475,0.000043717213,0.002217612,0.81401956,0.00009257065,0.0031293386,0.0007093519],"about_ca_topic_score_codex":0.000028376442,"about_ca_topic_score_gemma":0.000023984798,"teacher_disagreement_score":0.15429334,"about_ca_system_score_codex":0.00003234198,"about_ca_system_score_gemma":0.00012958742,"threshold_uncertainty_score":0.99995804},"labels":[],"label_agreement":null},{"id":"W2042259764","doi":"10.1038/ng0604-543","title":"A public gene trap resource for mouse functional genomics","year":2004,"lang":"en","type":"letter","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Manitoba","funders":"University of Toronto; Wellcome Trust","keywords":"Biology; GenBank; Genome; Gene; Genetics; Functional genomics; Genomic library; Genomics; Computational biology","score_opus":0.013541120888250052,"score_gpt":0.25482370246541186,"score_spread":0.24128258157716181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042259764","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.056229107,0.12158569,0.38063186,0.4204571,0.007938763,0.0050777677,0.0051834094,0.00038016264,0.0025161451],"genre_scores_gemma":[0.034106422,0.0026740842,0.04870183,0.8037088,0.051651545,0.0004749002,0.0366474,0.00095785677,0.021077156],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977059,0.000029138488,0.0003656244,0.0008748288,0.00033299217,0.0006915098],"domain_scores_gemma":[0.99861866,0.000024121236,0.00013636267,0.0008581786,0.00023637364,0.00012629866],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00014687619,0.00053610106,0.0003368317,0.0001490799,0.0001295573,0.00008881169,0.00052112027,0.0036481528,0.000024372786],"category_scores_gemma":[0.000083730265,0.0005809097,0.00038927913,0.00011183285,0.00007661866,0.0000017006837,0.00014940281,0.0016180576,0.000008646013],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003684307,0.000028988152,0.00001640856,0.00014798503,0.00022899284,0.000015125213,0.000014661017,0.0027282308,0.07988015,0.00000935015,0.91546065,0.0014326093],"study_design_scores_gemma":[0.0006993974,0.00017685934,0.000036238114,0.000009451356,0.00008335464,0.000074817915,0.0000049424348,0.00007246762,0.14389166,0.00010938228,0.85428065,0.0005607797],"about_ca_topic_score_codex":0.0000011139949,"about_ca_topic_score_gemma":0.000007427763,"teacher_disagreement_score":0.38325173,"about_ca_system_score_codex":0.00009939428,"about_ca_system_score_gemma":0.00040081536,"threshold_uncertainty_score":0.99966425},"labels":[],"label_agreement":null},{"id":"W2043083543","doi":"10.1038/nature11723","title":"Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system","year":2012,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":861,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Trans-activating crRNA; Biology; CRISPR interference; Gene; Bacteriophage; Genome; Genetics; Computational biology; DNA; RNA; Genome editing; Escherichia coli","score_opus":0.005317889830464292,"score_gpt":0.26814001038833446,"score_spread":0.2628221205578702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043083543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9722341,0.022109773,0.001735617,0.00020263123,0.0024388458,0.00018694316,0.000023724084,0.000035439025,0.0010329842],"genre_scores_gemma":[0.9973672,0.00015769059,0.000222957,0.00013288752,0.0016722315,0.00001825844,0.000074829295,0.000029436984,0.0003245079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923885,0.00004142205,0.000116168725,0.00017538588,0.000115994175,0.0003121767],"domain_scores_gemma":[0.9994336,0.000010250904,0.000048219525,0.00040513274,0.000032689186,0.0000701064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017354467,0.00016797369,0.00012567015,0.000020461956,0.00009947961,0.0000363701,0.00022568605,0.0006909128,0.000030899966],"category_scores_gemma":[0.000022344311,0.00011631803,0.00009756345,0.000057772042,0.000027397784,0.0000063198695,0.0001193664,0.0004865602,0.000017051216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044994405,0.000015341253,0.0010635031,0.000037232734,0.0000462932,0.0000017001682,0.000076844335,0.0000106609505,0.9958957,0.000091803624,0.0010562696,0.001659698],"study_design_scores_gemma":[0.00019672008,0.000025635605,0.019570967,0.000011616296,0.00001871298,0.00004984813,0.00014656592,0.0000064924448,0.7831775,7.5874357e-7,0.19666147,0.00013373917],"about_ca_topic_score_codex":0.000008430979,"about_ca_topic_score_gemma":0.0000034891596,"teacher_disagreement_score":0.21271819,"about_ca_system_score_codex":0.00001995939,"about_ca_system_score_gemma":0.000015566275,"threshold_uncertainty_score":0.53289527},"labels":[],"label_agreement":null},{"id":"W2043302496","doi":"10.1093/nar/gkp1223","title":"A unified genetic, computational and experimental framework identifies functionally relevant residues of the homing endonuclease I-BmoI","year":2010,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Homing endonuclease; Biology; Endonuclease; Computational biology; Function (biology); Linker; Homology (biology); Homology modeling; Cleavage (geology); Protein function; Mutant; Genetics; Amino acid; DNA; Biochemistry; Enzyme; Gene; Computer science","score_opus":0.015969596963096397,"score_gpt":0.3398975350941449,"score_spread":0.3239279381310485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043302496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966122,0.00072161015,0.0016502753,0.00020637277,0.00019548638,0.00016686537,0.000011568966,0.000008182527,0.00042742747],"genre_scores_gemma":[0.9925232,0.00004535276,0.0068502445,0.00003519605,0.00019631664,0.000014498842,0.000007944546,0.000021917967,0.0003053238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885887,0.00007364917,0.00017831344,0.00026919146,0.0003935743,0.00022638799],"domain_scores_gemma":[0.9993029,0.00008520979,0.00003329508,0.000334855,0.00016430278,0.00007940494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033114568,0.000099962046,0.00009162793,0.00006363853,0.00020719008,0.00004683801,0.00024604078,0.00013485311,0.000081368475],"category_scores_gemma":[0.00031846637,0.00008266377,0.000055529945,0.00012087501,0.00036367757,0.0000042420147,0.00034006173,0.00034167364,0.0000052675105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007598471,0.000042557305,0.0051396936,0.000021211163,0.000028705217,0.0000019104984,0.00022606195,0.00045734696,0.9918352,0.00070990896,0.0006669126,0.000794523],"study_design_scores_gemma":[0.0004431027,0.00017586286,0.19723248,0.00003364744,0.000008288445,0.000035004832,0.0006257074,0.000778052,0.79486805,0.001786983,0.0038573956,0.00015540363],"about_ca_topic_score_codex":0.000023749866,"about_ca_topic_score_gemma":0.000026413873,"teacher_disagreement_score":0.19696712,"about_ca_system_score_codex":0.000007949583,"about_ca_system_score_gemma":0.00007785951,"threshold_uncertainty_score":0.33709309},"labels":[],"label_agreement":null},{"id":"W2043788452","doi":"10.1139/o10-110","title":"Gene insulation. Part I: natural strategies in yeast and <i>Drosophila</i>","year":2010,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Enhancer; RNA polymerase III; Heterochromatin; Genetics; RNA polymerase II; Chromatin; Gene; Drosophila melanogaster; Transcription (linguistics); RNA polymerase; RNA; Promoter; Gene expression","score_opus":0.009855581152011893,"score_gpt":0.29694149887297416,"score_spread":0.28708591772096226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043788452","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.032351702,0.96646833,0.000015442685,0.0000072488942,0.00022664922,0.0001573396,0.000083999155,0.000009880748,0.00067938573],"genre_scores_gemma":[0.054445688,0.9435934,0.00018460889,0.000019904806,0.0004773052,0.00003572882,0.0009285712,0.000026135656,0.00028868846],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.998779,0.000033375167,0.00031748248,0.0005710453,0.000036454636,0.00026266265],"domain_scores_gemma":[0.9994899,0.000015372814,0.000102259844,0.0002852011,0.000020649684,0.00008660497],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000097799326,0.00035234322,0.0005064959,0.00004147676,0.000043085343,0.00003142601,0.00014333361,0.00084142387,0.000006317259],"category_scores_gemma":[0.000022145261,0.00031567935,0.00009371723,0.000069097274,0.0001586592,0.0000024618325,0.00015667896,0.0003590694,0.0000020022862],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016072565,0.000047318856,0.00009881514,0.0038945575,0.00005063025,0.0000086737,0.0000144033165,0.0000022927063,0.63622874,0.000039673985,0.00009464629,0.35950416],"study_design_scores_gemma":[0.00024408156,0.000048691596,0.000029559335,0.00021562878,0.000060145623,0.000088102366,0.00001741128,0.000004503384,0.047071397,0.000029706995,0.9517726,0.00041818956],"about_ca_topic_score_codex":0.0000051987504,"about_ca_topic_score_gemma":0.0000052433097,"teacher_disagreement_score":0.9516779,"about_ca_system_score_codex":0.000006963448,"about_ca_system_score_gemma":0.000112648035,"threshold_uncertainty_score":0.99992955},"labels":[],"label_agreement":null},{"id":"W2044275406","doi":"10.1111/dgd.12101","title":"Translating human genetics into mouse: The impact of ultra‐rapid <i>in vivo</i> genome editing","year":2013,"lang":"en","type":"review","venue":"Development Growth & Differentiation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Core Research for Evolutional Science and Technology; Institute of Genetics; Japan Science and Technology Agency; Tokyo Medical and Dental University","keywords":"Genome editing; Biology; Gene targeting; Genome; Gene knockin; Gene; Computational biology; CRISPR; Gene knockout; Genetics; Model organism; Embryonic stem cell","score_opus":0.016847672957344448,"score_gpt":0.311435440472083,"score_spread":0.29458776751473853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044275406","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.053679783,0.9395678,0.0052097663,0.000004875016,0.0001522916,0.0010463513,0.00003052929,0.000019460416,0.00028912193],"genre_scores_gemma":[0.18102121,0.81617343,0.00086575473,0.0000054235984,0.0003322388,0.00019415868,0.0012217019,0.00009224309,0.00009381021],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807924,0.00009671007,0.0008775306,0.00039986797,0.00020814616,0.00033848916],"domain_scores_gemma":[0.9991678,0.000020136826,0.00036773377,0.0002996232,0.00008210386,0.000062596824],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022541806,0.00044291827,0.0006387984,0.0001565421,0.00011165013,0.000044551154,0.000353883,0.000296041,0.00005060329],"category_scores_gemma":[0.000025418021,0.00032510888,0.00032616287,0.0001864201,0.00003347898,0.000005306798,0.00007099161,0.00021176695,0.0000039969864],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006574374,0.00019535968,0.0014918619,0.009979644,0.0010074915,0.0000015797431,0.0018847965,0.00035302909,0.4175346,0.000026267942,0.0002102336,0.56730855],"study_design_scores_gemma":[0.0035904448,0.0010122545,0.025902195,0.009989668,0.0016357579,0.00007692938,0.0004086643,0.00045096205,0.6032243,0.00013188635,0.34712434,0.0064526317],"about_ca_topic_score_codex":0.00003844945,"about_ca_topic_score_gemma":0.0000260956,"teacher_disagreement_score":0.5608559,"about_ca_system_score_codex":0.0000894342,"about_ca_system_score_gemma":0.00015297189,"threshold_uncertainty_score":0.99992007},"labels":[],"label_agreement":null},{"id":"W2044504165","doi":"10.1046/j.1365-2583.2000.00172.x","title":"<i>Mariner</i> ( <i>Mos</i> 1) transposase and genomic integration of foreign gene sequences in <i>Bombyx mori</i> cells","year":2000,"lang":"en","type":"article","venue":"Insect Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Medical Research Council","keywords":"Transposase; Biology; Transposition (logic); Transposable element; Tn10; Genetics; Plasmid; Bombyx mori; Bombyx; Transformation (genetics); Gene; Genome","score_opus":0.006122223229577326,"score_gpt":0.26396874225078415,"score_spread":0.2578465190212068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044504165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844897,0.0021516087,0.012131621,0.00003823526,0.00007720612,0.00020803312,0.000046474794,0.000010726236,0.00084641826],"genre_scores_gemma":[0.99541235,0.0012356592,0.0026355588,0.0003649299,0.000050509676,0.000024343077,0.00018610306,0.000023716511,0.000066822155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988802,0.00007924789,0.00032355555,0.00039366185,0.000057098583,0.00026619935],"domain_scores_gemma":[0.99957585,0.000012461362,0.000049052545,0.00026754115,0.000030103969,0.000064969536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014575623,0.0002050795,0.00023730299,0.00007677124,0.00002356525,0.000007983235,0.00016409617,0.00021680706,0.000024836563],"category_scores_gemma":[0.000011486662,0.00020020286,0.00008115192,0.00012301144,0.00013117841,0.0000034336306,0.00003513577,0.00010728607,0.000003105386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009010802,0.000034741428,0.0011180124,0.000017897912,0.000025145504,0.000013701537,0.00006034712,0.0011986323,0.9906781,0.0001233321,0.000027064627,0.0066129384],"study_design_scores_gemma":[0.00066322344,0.0003926015,0.00091010437,0.000012009679,0.000017213808,0.00004429035,0.000018113533,0.00022109148,0.99483585,0.00043332693,0.002232808,0.00021934698],"about_ca_topic_score_codex":0.00026878584,"about_ca_topic_score_gemma":0.0001501111,"teacher_disagreement_score":0.010922682,"about_ca_system_score_codex":0.000010388414,"about_ca_system_score_gemma":0.000044236047,"threshold_uncertainty_score":0.81640357},"labels":[],"label_agreement":null},{"id":"W2046388483","doi":"10.1016/j.jmb.2012.05.007","title":"High Levels of Wild-Type BRCA2 Suppress Homologous Recombination","year":2012,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"RAD51; Homologous recombination; BRCA2 Protein; Recombination; Biology; Molecular biology; Non-allelic homologous recombination; FLP-FRT recombination; Non-homologous end joining; Homologous chromosome; Genetic recombination; Small interfering RNA; DNA repair; Gene; RNA; Cell biology; Genetics; Mutation; Germline mutation","score_opus":0.010110095970766689,"score_gpt":0.32062860383106884,"score_spread":0.31051850786030216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046388483","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95918596,0.0044977097,0.035094667,0.00010072597,0.0009327575,0.00005755506,0.000009324987,0.0000028565764,0.00011842342],"genre_scores_gemma":[0.994456,0.00018526237,0.0049533295,0.00008387132,0.00023782295,0.0000010131457,0.000018476907,0.000016623091,0.00004762351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991006,0.00010203459,0.0003712776,0.00010933925,0.000085853855,0.00023089473],"domain_scores_gemma":[0.9992234,0.000016895916,0.00024834456,0.00019793327,0.00022629793,0.00008709016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036555235,0.00012121627,0.0002403616,0.00009713605,0.000018307157,0.0000038947655,0.00020015377,0.00020468594,0.000035766097],"category_scores_gemma":[0.00018900346,0.000108006316,0.00012738678,0.00008605736,0.00006123491,0.000004807791,0.00006735052,0.00012047607,0.0000021506182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055031873,0.00007799516,0.0018993989,0.0000130769,0.00011572196,0.0000046952673,0.000032044973,0.00033767126,0.99353826,0.0003642505,0.00027565984,0.0032861994],"study_design_scores_gemma":[0.00056710874,0.00084399886,0.008763874,0.000011648535,0.000045456978,0.00025259148,0.00002351081,0.00000589709,0.9853141,0.00034563206,0.0037023842,0.00012384464],"about_ca_topic_score_codex":0.0000054919005,"about_ca_topic_score_gemma":8.675814e-7,"teacher_disagreement_score":0.035269998,"about_ca_system_score_codex":0.000011365278,"about_ca_system_score_gemma":0.00004188037,"threshold_uncertainty_score":0.44043696},"labels":[],"label_agreement":null},{"id":"W2046804572","doi":"10.1016/j.stem.2010.03.014","title":"Multiple Epigenetic Modifiers Induce Aggressive Viral Extinction in Extraembryonic Endoderm Stem Cells","year":2010,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Children’s Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Stem cell; Embryonic stem cell; Endoderm; Cell biology; Argonaute; Epigenetics; Epiblast; Chromatin; Genetics; Gene silencing; RNA interference; Gene; RNA; Gastrulation","score_opus":0.007120971652296585,"score_gpt":0.23437524993632125,"score_spread":0.22725427828402467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046804572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906448,0.0020050146,0.0034933698,0.000009069037,0.0010454897,0.00036816826,0.000013058597,0.000026939246,0.002394078],"genre_scores_gemma":[0.9960708,0.00028523483,0.00039902466,0.000034815617,0.00022717222,0.000049765113,0.000027930271,0.00005681641,0.0028484121],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838954,0.000053363146,0.00033838488,0.00057359977,0.00015378738,0.00049134577],"domain_scores_gemma":[0.9990821,0.000029608951,0.00015232441,0.00052943744,0.000045668046,0.00016084447],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001582246,0.00029119392,0.00021073446,0.000091560694,0.000072673116,0.000036141562,0.00028167182,0.0003479474,0.000037643207],"category_scores_gemma":[0.0000046819778,0.00031177688,0.000120166944,0.00011051953,0.000053701548,0.0000060233597,0.000113758586,0.0003662163,0.000055723576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031433556,0.00009610505,0.00094614236,0.000065958564,0.0000073246565,0.000017095728,0.000165937,0.0044870065,0.9876494,0.0000018385442,0.00014427482,0.006387531],"study_design_scores_gemma":[0.0010628757,0.00012592271,0.0008474202,0.000012979172,0.000015128324,0.000010299429,0.00026425015,0.0021951874,0.98904115,0.0000072062094,0.006059877,0.00035769606],"about_ca_topic_score_codex":0.000028650325,"about_ca_topic_score_gemma":0.0001558473,"teacher_disagreement_score":0.006029835,"about_ca_system_score_codex":0.000025418123,"about_ca_system_score_gemma":0.00008446568,"threshold_uncertainty_score":0.9999334},"labels":[],"label_agreement":null},{"id":"W2046856427","doi":"10.1016/s0027-5107(00)00081-6","title":"Mutant frequencies and mutation spectra of dimethylnitrosamine (DMN) at the lacI and cII loci in the livers of Big Blue® transgenic mice","year":2000,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Cancer Institute; National Institutes of Health","keywords":"Lac repressor; Mutant; Mutation; Molecular biology; Genetics; Gene; Biology; Mutation frequency; Mutagen; Chemistry; DNA; lac operon; Plasmid","score_opus":0.01673096203231349,"score_gpt":0.2980733745477042,"score_spread":0.2813424125153907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046856427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99229366,0.003189129,0.0038319041,0.00018202612,0.000015603558,0.00036275884,0.000060921135,0.0000024061706,0.000061572995],"genre_scores_gemma":[0.9978133,0.0013297574,0.00065934646,0.000042945485,0.000010939337,0.000022354945,0.00005187608,0.00001330563,0.000056171903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998816,0.0001875156,0.0002546361,0.00024359458,0.00031286728,0.00018538974],"domain_scores_gemma":[0.99959797,0.000068186855,0.00005931053,0.00016530661,0.00006409514,0.00004512366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060796784,0.00012575572,0.00015788466,0.000102893166,0.00008899191,0.000015849077,0.00012025203,0.0000752756,0.000030534942],"category_scores_gemma":[0.000035211146,0.000094530886,0.000054107804,0.00019043134,0.0003244288,0.00000651876,0.0000566894,0.00007691656,3.8007036e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000112520545,0.000050820294,0.000057576035,0.00010814989,0.00005169177,0.000009285959,0.0014032554,0.00039505065,0.9879496,0.00018153749,0.0000037110115,0.009676819],"study_design_scores_gemma":[0.00065852236,0.00056441326,0.0024193143,0.000021957268,0.00003986058,0.000046421537,0.0036873461,0.00027179823,0.99154097,0.0005594038,0.000096079326,0.0000939283],"about_ca_topic_score_codex":0.00028081067,"about_ca_topic_score_gemma":0.0001798079,"teacher_disagreement_score":0.00958289,"about_ca_system_score_codex":0.000012742496,"about_ca_system_score_gemma":0.00002800584,"threshold_uncertainty_score":0.38548577},"labels":[],"label_agreement":null},{"id":"W2047791375","doi":"10.1139/cjm-2015-0049","title":"The animal gut as a melting pot for horizontal gene transfer","year":2015,"lang":"en","type":"review","venue":"Canadian Journal of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Israel Science Foundation","keywords":"Horizontal gene transfer; Biology; Adaptation (eye); Gastrointestinal tract; Gene; Gene transfer; Genetics; Evolutionary biology; Microorganism; Bacteria; Phylogenetics; Biochemistry; Neuroscience","score_opus":0.019601291371395525,"score_gpt":0.3152952244686905,"score_spread":0.29569393309729497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047791375","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009516739,0.996824,0.0006814233,0.00006243743,0.000832422,0.00029060876,0.00024608363,0.0000014675029,0.00010983852],"genre_scores_gemma":[0.0014861411,0.9960725,0.00036465845,0.000060944232,0.0013173016,0.000016570995,0.00022492558,0.00006525411,0.0003917383],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986699,0.00009050937,0.0005351721,0.00021589671,0.00002954037,0.0004589728],"domain_scores_gemma":[0.99904156,0.000043511795,0.0001444545,0.00021489158,0.00020438885,0.0003512095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000575578,0.0002677053,0.0006634668,0.00010881656,0.0001360964,0.00003403085,0.0004936606,0.0004368876,0.000013803723],"category_scores_gemma":[0.00015102445,0.00019028276,0.000513408,0.000058815065,0.000109917,0.000001580215,0.000020526188,0.0002678566,0.000009201037],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011587664,0.000015650974,0.0000050404024,0.0011482169,0.0013873788,0.00013075418,0.00013543632,0.000018255045,0.13305795,0.00013600735,0.0438672,0.81998223],"study_design_scores_gemma":[0.00026485944,0.00054730225,4.351069e-7,0.00023198781,0.00024552597,0.0036784466,0.00003321534,3.5823604e-7,0.0017362816,0.000007849431,0.9930457,0.0002080227],"about_ca_topic_score_codex":0.00010802364,"about_ca_topic_score_gemma":0.0038084113,"teacher_disagreement_score":0.9491785,"about_ca_system_score_codex":0.000088386856,"about_ca_system_score_gemma":0.0029398198,"threshold_uncertainty_score":0.7759506},"labels":[],"label_agreement":null},{"id":"W2048122201","doi":"10.1002/em.20549","title":"A novel <i>Escherichia coli</i>‐derived mutation detected with the Big Blue® <i>cII</i> mutant selectable assay","year":2010,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mutant; Biology; Point mutation; Escherichia coli; Mutation; Transposable element; Genetics; Molecular biology; Mutation frequency; Mutagen; Transgene; Plasmid; Mutagenesis; Gene; DNA","score_opus":0.002605563172477003,"score_gpt":0.19121299180505774,"score_spread":0.18860742863258073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048122201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93547493,0.00047650593,0.06343957,0.00010602769,0.00008313679,0.0002746591,0.000026607797,0.000020061414,0.00009847295],"genre_scores_gemma":[0.9965639,0.000079424404,0.0024503795,0.00044924198,0.00008888151,0.00007123781,0.00009223713,0.000051771316,0.00015293715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989573,0.00003615221,0.00013638173,0.00040517538,0.00017478717,0.00029020972],"domain_scores_gemma":[0.9994954,0.000012306158,0.000055057735,0.0003138433,0.000010187096,0.00011322394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230041,0.00024735407,0.00013030806,0.000026537999,0.00017054427,0.000042090065,0.0001428731,0.00012817665,0.000019791625],"category_scores_gemma":[0.000011747788,0.00018809306,0.00006141968,0.000080635284,0.00015013981,0.0000044249646,0.00009805798,0.00015208426,0.0000071108257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004696688,0.000059694736,0.00019779406,0.000008095803,0.00007910435,0.000018205046,0.00008862885,0.00043440532,0.9966857,0.000004493685,0.000017409671,0.0023595036],"study_design_scores_gemma":[0.00068817724,0.00019128757,0.007634119,0.0000033142758,0.0000779361,0.00016816733,0.00016655581,0.00030115762,0.9843015,0.000001923066,0.006174349,0.00029151837],"about_ca_topic_score_codex":0.000021682894,"about_ca_topic_score_gemma":0.00006340794,"teacher_disagreement_score":0.061088935,"about_ca_system_score_codex":0.000009303998,"about_ca_system_score_gemma":0.000026916321,"threshold_uncertainty_score":0.76702124},"labels":[],"label_agreement":null},{"id":"W2049474570","doi":"10.1002/em.20613","title":"Germ cell mutagens: Risk assessment challenges in the 21st century","year":2010,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"De La Salle University; U.S. Environmental Protection Agency","keywords":"Germline; Germline mutation; Biology; Mutation; Genetics; Mutagen; Computational biology; Somatic cell; Risk analysis (engineering); Biotechnology; Business; Carcinogen; Gene","score_opus":0.011216791759091937,"score_gpt":0.2816881795630943,"score_spread":0.2704713878040023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049474570","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006585311,0.9912041,0.000085189065,0.000020698937,0.00016039245,0.0006302475,0.00011765617,0.000008181246,0.0011882227],"genre_scores_gemma":[0.017000834,0.98170453,0.00036636638,0.000065930755,0.0001524586,0.00018528967,0.0003910806,0.00008283473,0.00005066378],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980176,0.0002743881,0.00037711955,0.00072907534,0.00023531736,0.0003665155],"domain_scores_gemma":[0.99898595,0.000030976094,0.00017214972,0.00070732436,0.0000028527224,0.000100737314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003600794,0.00053225126,0.000560333,0.000083247956,0.00009622331,0.00004267669,0.00037606858,0.00047197126,0.00002489009],"category_scores_gemma":[0.000010150623,0.00040193772,0.00035340674,0.000050564628,0.00010214262,0.000003148323,0.000265842,0.00046716013,0.000020376614],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000024758044,0.00015247462,0.000037257334,0.0009660151,0.00008033885,0.00006671887,0.00008654808,0.000008970056,0.014362675,0.000018850476,0.000016018756,0.98420167],"study_design_scores_gemma":[0.00021961043,0.00010093305,0.00037532917,0.00012620927,0.0003508058,0.000092871735,0.0003803301,0.0000025637503,0.0017632664,0.0000046769624,0.996097,0.0004863584],"about_ca_topic_score_codex":0.000006614248,"about_ca_topic_score_gemma":0.000010650571,"teacher_disagreement_score":0.99608105,"about_ca_system_score_codex":0.000027606104,"about_ca_system_score_gemma":0.00003651559,"threshold_uncertainty_score":0.99984324},"labels":[],"label_agreement":null},{"id":"W2049519756","doi":"10.1002/anie.200502666","title":"Photochemical Regulation of DNA‐Binding Specificity of MyoD","year":2005,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"MyoD; Linker; Isomerization; DNA; Azobenzene; Helix (gastropod); Chemistry; Conformational isomerism; Biophysics; Sequence (biology); Photoisomerization; Computational biology; Computer science; Biochemistry; Biology; Gene; Molecule; Transcription factor","score_opus":0.009668427652655232,"score_gpt":0.2819756325606184,"score_spread":0.2723072049079632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049519756","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97399837,0.000074532625,0.020642228,0.00015320884,0.00030498227,0.00007720474,0.00006724797,0.0000085121965,0.0046737078],"genre_scores_gemma":[0.9965715,0.00005299629,0.0014323319,0.000019806614,0.0010808508,0.0000073524675,0.00056988344,0.000008818434,0.00025650035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939334,0.000004419659,0.00021603757,0.00014115626,0.00016850904,0.00007652561],"domain_scores_gemma":[0.9996153,0.000009783611,0.00009945386,0.000114261464,0.0001347432,0.000026454663],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007783874,0.000074298034,0.00008334283,0.000044374665,0.0000116937545,0.000004361891,0.00010401283,0.000084875195,0.00015337557],"category_scores_gemma":[0.00005928353,0.00008118322,0.00007105057,0.000043303487,0.000037702746,0.000007532722,0.00003600921,0.00004182115,0.0000028417276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004142299,0.000046893038,0.00040474435,0.000013638247,0.000029275432,1.1548706e-7,0.00003119075,0.00022079344,0.9956651,0.00006242479,0.0030240933,0.00046030554],"study_design_scores_gemma":[0.00029511083,0.000031180738,0.0019185424,0.00002602239,0.000008518484,0.0000052806663,0.000024387973,0.00016253538,0.98817533,0.000056608373,0.009221933,0.00007454338],"about_ca_topic_score_codex":0.0000036372496,"about_ca_topic_score_gemma":0.0000033474664,"teacher_disagreement_score":0.022573084,"about_ca_system_score_codex":0.000023065737,"about_ca_system_score_gemma":0.000014116368,"threshold_uncertainty_score":0.33105558},"labels":[],"label_agreement":null},{"id":"W2050097902","doi":"10.3109/07388551.2011.593503","title":"Advances in directed molecular evolution of reporter genes","year":2011,"lang":"en","type":"review","venue":"Critical Reviews in Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Innovates","funders":"","keywords":"Directed evolution; Reporter gene; Computational biology; DNA shuffling; Gene; Biology; Directed Molecular Evolution; Transgene; Function (biology); Molecular evolution; Green fluorescent protein; Genetics; Genome; Gene expression; Mutant","score_opus":0.021985569019218557,"score_gpt":0.3828106500639667,"score_spread":0.36082508104474814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050097902","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001967821,0.99175227,0.006930477,0.00001526574,0.0002394915,0.0005800454,0.000008765698,0.000022998169,0.00043102884],"genre_scores_gemma":[0.00023730645,0.9967386,0.0026716695,0.000008951608,0.000048642345,0.00020246726,0.000038912647,0.000037151538,0.00001629893],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975713,0.00016913006,0.0012087529,0.00061646884,0.00006680314,0.00036755085],"domain_scores_gemma":[0.9989526,0.000033574634,0.00018016763,0.00074719655,0.000039622642,0.000046828118],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003815456,0.00035221284,0.0015213932,0.00035628947,0.000009111504,0.0000027578399,0.00037261774,0.001181257,0.000015973683],"category_scores_gemma":[0.001447329,0.0003097516,0.00031278777,0.00048322044,0.0002617261,0.0000034778147,0.00019338867,0.00034281582,0.000008197359],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034342968,0.000058401572,0.000011572964,0.007955899,0.000009138606,0.000017396846,0.0000016599379,7.7828935e-7,0.0022725281,0.002965117,0.000026138236,0.98667794],"study_design_scores_gemma":[0.00007788644,0.00010081601,0.0000054328943,0.005460432,0.000080628684,0.00007561231,0.0000029634496,0.0000035963149,0.002911548,0.0004261701,0.9905632,0.00029169288],"about_ca_topic_score_codex":0.000007958445,"about_ca_topic_score_gemma":0.00004319586,"teacher_disagreement_score":0.9905371,"about_ca_system_score_codex":0.00004594793,"about_ca_system_score_gemma":0.00008169156,"threshold_uncertainty_score":0.99993545},"labels":[],"label_agreement":null},{"id":"W2050229128","doi":"10.1038/mt.2013.131","title":"Kinetics and Epigenetics of Retroviral Silencing in Mouse Embryonic Stem Cells Defined by Deletion of the D4Z4 Element","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene silencing; DNA methylation; Epigenetics; Heterochromatin; Chromatin; Long terminal repeat; Genetics; Epigenomics; Histone; Cell biology; Gene; Gene expression","score_opus":0.004625039397021742,"score_gpt":0.22372407886817872,"score_spread":0.21909903947115697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050229128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846389,0.004556034,0.01038151,0.00005274519,0.00004458521,0.00028903244,0.0000102255435,0.0000030649674,0.00002384798],"genre_scores_gemma":[0.9981175,0.00093539996,0.0007040257,0.000077164375,0.000009313241,0.000016434167,0.000008124771,0.000021541036,0.000110511806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922305,0.00005389982,0.0002446086,0.00018172163,0.00012791155,0.0001688128],"domain_scores_gemma":[0.99951273,0.0000073249917,0.000084851665,0.00031114594,0.000051744617,0.00003219775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008288227,0.0001276072,0.0001395896,0.000031347783,0.000014238683,0.0000076921415,0.00014805238,0.00009289999,0.000006495109],"category_scores_gemma":[0.0000063619304,0.00010671682,0.000062405124,0.000082520295,0.000050516657,0.0000017092352,0.00006196751,0.00006158259,5.3603e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009634106,0.000051233266,0.001617805,0.000021447455,0.000019896366,2.0156152e-7,0.00005726843,0.0019505954,0.99226606,0.000011600922,0.00005647618,0.0039378065],"study_design_scores_gemma":[0.0005511733,0.00031225485,0.0020870336,0.00001306446,0.0000056322433,7.806168e-7,0.000060339244,0.0003605167,0.9960277,0.000021072969,0.00045183292,0.00010859717],"about_ca_topic_score_codex":0.00004952361,"about_ca_topic_score_gemma":0.000010182747,"teacher_disagreement_score":0.01347853,"about_ca_system_score_codex":0.000010323994,"about_ca_system_score_gemma":0.000013594928,"threshold_uncertainty_score":0.43517855},"labels":[],"label_agreement":null},{"id":"W2050622268","doi":"10.1038/sj.mt.6300073","title":"Real-time Fluorescence Tracking of Dynamic Transgene Variegation in Stem Cells","year":2007,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Variegation (histology); Transgene; Biology; Epigenetics; Gene silencing; Retrovirus; DNA methylation; Cell biology; Genetics; Gene; Gene expression","score_opus":0.005551091713710162,"score_gpt":0.2713864993019838,"score_spread":0.2658354075882736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050622268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9096367,0.0007345405,0.089222014,0.000012668938,0.000049576047,0.00015554759,0.0000033697331,0.00000964723,0.00017593546],"genre_scores_gemma":[0.99629754,0.0005948483,0.0029476457,0.0000235801,0.000017174372,0.00000415582,0.000018995446,0.000025972055,0.00007007581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991966,0.000028655122,0.00023328976,0.00022070405,0.00011489093,0.00020586775],"domain_scores_gemma":[0.9996307,0.000008176415,0.00004393504,0.00024010368,0.00003713021,0.00003995462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027424304,0.00012131582,0.00012557732,0.000068087706,0.0000150041205,0.0000069161906,0.0001293998,0.00011024319,0.000009165624],"category_scores_gemma":[0.000002631586,0.00012958053,0.00007163679,0.00013346199,0.000027386594,0.000002290935,0.000011242452,0.00005542699,0.000002476951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007675102,0.000042725358,0.00014062756,0.000011007487,0.0000177044,0.000009324534,0.00012411227,0.0011970451,0.96451145,0.000013680975,0.0000025390043,0.033853006],"study_design_scores_gemma":[0.0005372284,0.00013588142,0.0041785184,0.000014895536,0.0000036461117,0.000002613147,0.000025929749,0.00061866513,0.99411726,0.000019757896,0.00021122376,0.00013435622],"about_ca_topic_score_codex":0.000021695863,"about_ca_topic_score_gemma":0.000014882071,"teacher_disagreement_score":0.086660855,"about_ca_system_score_codex":0.000013418952,"about_ca_system_score_gemma":0.00002131377,"threshold_uncertainty_score":0.5284141},"labels":[],"label_agreement":null},{"id":"W2050646153","doi":"10.1007/s13562-012-0128-z","title":"Gene technology in agriculture, environment and biopharming: beyond Bt-rice and building better breeding budgets for crops","year":2012,"lang":"en","type":"article","venue":"Journal of Plant Biochemistry and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biotechnology; Biology; Agriculture; Multinational corporation; Genetically modified crops; Bt cotton; Green Revolution; Agricultural biotechnology; Crop; Gene technology; Business; Gene; Agronomy; Ecology; Transgene; Genetics","score_opus":0.004782703961022374,"score_gpt":0.23143590467449082,"score_spread":0.22665320071346845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050646153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9799203,0.016885981,0.0018532403,0.0011208147,0.00007952667,0.00008985158,0.000037216534,0.0000069123853,0.000006156948],"genre_scores_gemma":[0.9868459,0.003891095,0.008902795,0.00006233572,0.0002412923,0.00000589574,0.000013627259,0.000010685908,0.000026372956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991512,0.000006445775,0.0002707279,0.00021873496,0.000057846697,0.00029504683],"domain_scores_gemma":[0.9996343,0.000018408024,0.000138638,0.00009942502,0.000019292575,0.00008990698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019354564,0.00017330615,0.00022017365,0.00013939208,0.00005648037,0.000013485827,0.00010660144,0.00052893016,9.627223e-7],"category_scores_gemma":[0.000054061493,0.00014532232,0.00003362287,0.00006810701,0.00012907706,0.0000079288275,0.00015075348,0.00022166866,9.592253e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046138346,0.000033816148,0.0052642305,0.0000691767,0.0000447449,0.000008895982,0.00001810767,0.000003311186,0.9909061,0.00004337039,0.000118320866,0.0034437713],"study_design_scores_gemma":[0.0006807718,0.00022478918,0.00096471247,0.000031138155,0.000036762267,0.0021726352,0.00013931064,0.000015371896,0.9863345,0.00009906287,0.009122313,0.0001786317],"about_ca_topic_score_codex":0.0000017685511,"about_ca_topic_score_gemma":5.601726e-7,"teacher_disagreement_score":0.012994885,"about_ca_system_score_codex":0.0000128219435,"about_ca_system_score_gemma":0.000009306033,"threshold_uncertainty_score":0.5926072},"labels":[],"label_agreement":null},{"id":"W2051088451","doi":"10.1126/science.aaa5945","title":"The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations","year":2015,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":636,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; University of California, San Diego; National Institutes of Health; Ryerson University","keywords":"Genetics; Allele; Mutation; Biology; Mutant; Phenotype; Gene; Compound heterozygosity; Heterozygote advantage","score_opus":0.01990074780604358,"score_gpt":0.37637904975585473,"score_spread":0.35647830194981117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051088451","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45226926,0.00047124072,0.5451295,0.0006581353,0.0006576478,0.0003539592,0.0000057660504,0.000022056578,0.0004324735],"genre_scores_gemma":[0.9806937,0.0000060976695,0.018302359,0.00019531454,0.00014776071,0.00007230745,0.000003674289,0.000008237424,0.00057056133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930817,0.000013393388,0.00009894297,0.00022595191,0.00012457395,0.00022898571],"domain_scores_gemma":[0.9994558,0.000025621956,0.00002376932,0.00023247415,0.00013451182,0.00012779229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007760587,0.0000614499,0.000046303438,0.000029417739,0.00025049975,0.00004162376,0.00022885343,0.000024366816,4.5701177e-7],"category_scores_gemma":[0.0005332692,0.000048334903,0.000032220672,0.00019358654,0.000080591635,0.00000349696,0.000070690185,0.000030146663,0.000006121675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014322595,0.0000058170103,0.000020548505,0.0000024815297,0.000004753109,7.78782e-7,0.00027450672,0.002262707,0.9736073,0.00007962799,0.00026392593,0.023463245],"study_design_scores_gemma":[0.00035906912,0.0003131364,0.000575911,0.000005621036,0.000010377982,0.000101336394,0.00097043155,0.009782883,0.8648742,0.00030643572,0.1225069,0.00019373458],"about_ca_topic_score_codex":0.000009463326,"about_ca_topic_score_gemma":0.000028575094,"teacher_disagreement_score":0.52842444,"about_ca_system_score_codex":0.00001988091,"about_ca_system_score_gemma":0.00011961541,"threshold_uncertainty_score":0.19710402},"labels":[],"label_agreement":null},{"id":"W2051156063","doi":"10.1159/000334050","title":"Low Levels of X-Inactive Specific Transcript in Somatic Cell Nuclear Transfer Embryos Derived from Female Bovine Freemartin Donor Cells","year":2011,"lang":"en","type":"article","venue":"Sexual Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research; Ontario Ministry of Food and Agriculture","keywords":"Somatic cell nuclear transfer; Biology; Embryo; Blastocyst; Andrology; XIST; Molecular biology; Embryogenesis; Genetics; Gene; X-inactivation; X chromosome","score_opus":0.019631907385971384,"score_gpt":0.2289341066681611,"score_spread":0.20930219928218974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051156063","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788744,0.00023729393,0.01978811,0.000005233313,0.00016683672,0.00025199566,0.000035357913,0.000011980307,0.0006287876],"genre_scores_gemma":[0.9888403,0.000029295432,0.010746543,0.00003169267,0.00003757394,0.000015891197,0.000037518177,0.00003627283,0.00022491321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987887,0.000034564655,0.0004051781,0.00035798096,0.00013119537,0.0002823492],"domain_scores_gemma":[0.9995894,0.00000899428,0.000036417376,0.0002443299,0.00003531522,0.00008557054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010235329,0.00021438953,0.00024160075,0.00006123051,0.000030425965,0.000007899785,0.00019033613,0.00012644757,0.0003361378],"category_scores_gemma":[0.000004257885,0.0002203575,0.00004769597,0.00008000254,0.00004889931,0.000005240366,0.000039627103,0.00009290372,0.000031864605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010838697,0.00022790126,0.0005175259,0.00008186543,0.000041888874,0.000007324392,0.0074404133,0.000066584544,0.98770136,0.0000034614602,0.000041256568,0.0037620603],"study_design_scores_gemma":[0.00081259053,0.00018974401,0.06319365,0.000031018095,0.0000096707945,9.45384e-7,0.0012724046,0.00002927825,0.93315274,0.000007970591,0.0010400154,0.00026000122],"about_ca_topic_score_codex":0.00004185851,"about_ca_topic_score_gemma":0.00011779943,"teacher_disagreement_score":0.062676124,"about_ca_system_score_codex":0.00002699305,"about_ca_system_score_gemma":0.00006921917,"threshold_uncertainty_score":0.8985918},"labels":[],"label_agreement":null},{"id":"W2051838004","doi":"10.1097/00001888-200101000-00009","title":"Ethical Issues of Human Germ-cell Therapy","year":2001,"lang":"en","type":"article","venue":"Academic Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Germ cell; Genetic enhancement; Psychological intervention; Somatic cell; Environmental ethics; Medicine; Biology; Genetics; Gene; Psychiatry","score_opus":0.023540473604672495,"score_gpt":0.39594513513940843,"score_spread":0.37240466153473595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051838004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787096,0.014253348,0.0018185917,0.0018687077,0.000112135676,0.00008634639,8.957903e-7,0.000012177306,0.0031382295],"genre_scores_gemma":[0.9841648,0.011450597,0.000055940207,0.00089027523,0.0007836106,0.0000047590815,0.000026081878,0.000014837914,0.002609116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992479,0.0000305367,0.0002393976,0.0001755375,0.00014861034,0.00015798668],"domain_scores_gemma":[0.9996055,0.000016789092,0.000055026132,0.00021427589,0.00003826987,0.00007018109],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032848993,0.00010578071,0.00016402415,0.00003515871,0.000023933944,8.3343093e-7,0.00017287163,0.0003644127,0.00012716351],"category_scores_gemma":[0.00008185363,0.000082991784,0.000032179498,0.00006886583,0.000113163245,7.5215127e-7,0.000035129462,0.00035489802,0.0000040611076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018581635,0.000004834164,0.0028947827,0.000013224249,0.000012180658,0.0000018789001,0.00032732746,0.000013633017,0.9847048,0.00012551286,0.010612928,0.0012703364],"study_design_scores_gemma":[0.0009738433,0.0005014369,0.0020018523,0.000039109276,0.000011915194,0.000019296162,0.0002083809,0.000022590568,0.79378355,0.0002614136,0.20205194,0.0001246703],"about_ca_topic_score_codex":0.000029950561,"about_ca_topic_score_gemma":0.0000016275277,"teacher_disagreement_score":0.19143902,"about_ca_system_score_codex":0.0000028616819,"about_ca_system_score_gemma":0.000012603261,"threshold_uncertainty_score":0.33843067},"labels":[],"label_agreement":null},{"id":"W2052628487","doi":"10.1080/03601234.2011.586598","title":"Investigation on gene transfer from genetically modified corn (<i>Zea mays</i>L.) plants to soil bacteria","year":2011,"lang":"en","type":"article","venue":"Journal of Environmental Science and Health Part B","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Environment and Climate Change Canada; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; University of Guelph","keywords":"Kanamycin; Biology; Bacteria; Neomycin; Population; Gene; Genetically modified organism; Microbiology; Botany; Genetics; Antibiotics","score_opus":0.04326098712093413,"score_gpt":0.28142071563252175,"score_spread":0.23815972851158762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052628487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979525,0.00019247842,0.0012083843,0.0002793524,0.0001656571,0.00008331549,0.000028314611,0.0000013986559,0.00008857572],"genre_scores_gemma":[0.9960591,0.0006506784,0.0014063097,0.0016926858,0.00015119209,0.0000019096144,0.000006118159,0.000006592344,0.000025417867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991319,0.00001684316,0.00024117717,0.00018220356,0.00022499151,0.00020288458],"domain_scores_gemma":[0.9994803,0.0000035095013,0.00004737777,0.000107059794,0.000008969055,0.0003527734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034704385,0.00008819399,0.00011163631,0.000043291297,0.000092684386,0.000013378697,0.00012745292,0.000040430754,0.000031209885],"category_scores_gemma":[0.0000070926685,0.00007578529,0.000024348468,0.00003636834,0.00011793184,0.000007888424,0.000033615535,0.0000656106,0.0000048977236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006521515,0.00003213913,0.0019800887,0.0000029645385,0.000006293179,0.0000027764022,0.00037470233,0.00009858397,0.99237686,0.0000041957737,0.00032832238,0.0047278493],"study_design_scores_gemma":[0.00037549264,0.0011268873,0.2866075,0.000025541989,0.000005849395,0.00002725767,0.00011354893,0.00004773724,0.7095554,0.00003672043,0.0019663183,0.00011174008],"about_ca_topic_score_codex":0.000027614571,"about_ca_topic_score_gemma":0.000020060199,"teacher_disagreement_score":0.28462744,"about_ca_system_score_codex":0.0000316189,"about_ca_system_score_gemma":0.000078776604,"threshold_uncertainty_score":0.30904347},"labels":[],"label_agreement":null},{"id":"W2052659698","doi":"10.1517/14712598.2015.1001735","title":"Communicating in context: a priority for gene therapy researchers","year":2015,"lang":"en","type":"editorial","venue":"Expert Opinion on Biological Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; NeuroDevNet","funders":"University of British Columbia; Canada Research Chairs","keywords":"Context (archaeology); Public opinion; Ethical issues; Engineering ethics; Public involvement; Bioethics; Political science; Public relations; Medicine; Biology; Politics; Engineering","score_opus":0.13378243306530818,"score_gpt":0.45526483396988165,"score_spread":0.3214824009045735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052659698","genre_codex":"editorial","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02979701,0.45467198,0.002012179,0.0012157502,0.50669503,0.004188384,0.0005167909,0.00015422136,0.0007486751],"genre_scores_gemma":[0.0218771,0.6466126,0.001701739,0.00058704044,0.3251114,0.00077189825,0.0031609694,0.00009827402,0.000078994744],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99778575,0.00032876118,0.00039705564,0.00069434574,0.00030962678,0.00048445744],"domain_scores_gemma":[0.9983403,0.0004018879,0.00011729918,0.0007681932,0.000226437,0.00014586505],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0011652173,0.00040450515,0.00047652956,0.000077190685,0.000089301924,0.00004131664,0.00076099054,0.0013710409,0.000018047434],"category_scores_gemma":[0.0009266858,0.00030658868,0.00021578284,0.00010060063,0.00013584812,0.00000238479,0.00014433298,0.0006017814,0.0000049327764],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028669797,0.0003373025,0.000046570167,0.000004717505,0.0001030912,0.0000012723883,0.00037392866,0.000027593436,0.10360951,0.000023511282,0.76373976,0.12886578],"study_design_scores_gemma":[0.0028791835,0.002575938,0.000042038682,0.000042335327,9.470154e-8,6.2290525e-7,0.000105689076,0.000028334889,0.022954784,0.00008208559,0.97090036,0.0003885126],"about_ca_topic_score_codex":0.000078451194,"about_ca_topic_score_gemma":0.000016077713,"teacher_disagreement_score":0.20716064,"about_ca_system_score_codex":0.00007692068,"about_ca_system_score_gemma":0.00019428489,"threshold_uncertainty_score":0.9999386},"labels":[],"label_agreement":null},{"id":"W2053105461","doi":"10.1093/nar/gkt871","title":"UV light-induced DNA lesions cause dissociation of yeast RNA polymerases-I and establishment of a specialized chromatin structure at rRNA genes","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Biology; Genetics; Chromatin; DNA; Gene; RNA; Ribosomal RNA; Polymerase; Yeast; Molecular biology","score_opus":0.020722114063274386,"score_gpt":0.3317006974231753,"score_spread":0.3109785833599009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053105461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982139,0.0008141088,0.000046780242,0.00017650666,0.00005364371,0.00030315362,0.000052349464,0.0000058260084,0.00033377355],"genre_scores_gemma":[0.9987996,0.00028754288,0.0003548432,0.000007318113,0.0001427885,0.00001581685,0.000045002715,0.0000217943,0.0003252809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988246,0.00008414633,0.00023829413,0.00023944401,0.0003453377,0.0002681919],"domain_scores_gemma":[0.9993099,0.000022722268,0.00006808907,0.00030565012,0.00018468461,0.000108948894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017766707,0.00011575494,0.00018048889,0.00010009556,0.00009249889,0.000024777633,0.00015919578,0.00014734898,0.00022759059],"category_scores_gemma":[0.00013248833,0.00010372531,0.0000515537,0.0001648281,0.000075136304,0.000007129429,0.0002404104,0.00010170253,0.0000042602746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028635717,0.000034486027,0.0025348077,0.000051545536,0.000048494436,8.162353e-7,0.00027818535,0.0000063055068,0.98967206,0.00002223564,0.000933686,0.0063887606],"study_design_scores_gemma":[0.00044299022,0.00018180415,0.06417106,0.000024580135,0.000010596786,0.0000033981996,0.00021878473,0.00008950618,0.9341691,0.000033164935,0.0005595652,0.00009545064],"about_ca_topic_score_codex":0.00022676567,"about_ca_topic_score_gemma":0.00010043242,"teacher_disagreement_score":0.06163625,"about_ca_system_score_codex":0.00003334369,"about_ca_system_score_gemma":0.000055867273,"threshold_uncertainty_score":0.42297953},"labels":[],"label_agreement":null},{"id":"W2053229995","doi":"10.1007/s10930-008-9147-y","title":"Single Molecule Assays Reveal Differences Between In Vitro and In Vivo Synthesized β-Galactosidase","year":2008,"lang":"en","type":"article","venue":"The Protein Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"","keywords":"In vivo; Enzyme; In vitro; Molecular biology; Biochemistry; Enzyme assay; Escherichia coli; Chemistry; Biology; Gene","score_opus":0.014871523919700352,"score_gpt":0.2530192963113063,"score_spread":0.23814777239160598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053229995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99560183,0.0010575927,0.0027104253,0.00028129522,0.000020878439,0.00015708034,0.000003858087,0.0000035000155,0.00016352221],"genre_scores_gemma":[0.9988864,0.00010324901,0.0006967977,0.0000230661,0.0001480122,0.000012916589,0.0000011831721,0.000011406023,0.00011696921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924916,0.00010501386,0.0001984961,0.00013337327,0.00010184439,0.00021212897],"domain_scores_gemma":[0.9997248,0.000021997426,0.000050307703,0.00012280582,0.00001625217,0.00006383352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002983597,0.00010872723,0.00014312586,0.000051484167,0.000075671436,0.000022337323,0.00014230267,0.00006890232,0.0000086788805],"category_scores_gemma":[0.000102727856,0.00007882286,0.000036754212,0.00006546031,0.00006194122,0.0000035976016,0.000055984026,0.00020840424,6.5727136e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074709504,0.000023574114,0.0069820643,0.000005944027,0.000009769563,0.000020930427,0.00011618245,0.000016735894,0.99168843,7.4389965e-7,0.000023728897,0.0010371609],"study_design_scores_gemma":[0.00050554785,0.00009147622,0.023587655,0.000038606257,0.000005150407,0.00014640678,0.000045252284,0.000047224243,0.9751808,0.00009358741,0.00014596758,0.000112344125],"about_ca_topic_score_codex":0.00001628468,"about_ca_topic_score_gemma":0.00001296975,"teacher_disagreement_score":0.016605591,"about_ca_system_score_codex":0.000012824296,"about_ca_system_score_gemma":0.000030785457,"threshold_uncertainty_score":0.3214303},"labels":[],"label_agreement":null},{"id":"W2053461321","doi":"10.1139/g07-005","title":"Genome-wide high-frequency non-Mendelian loss of heterozygosity in rice","year":2007,"lang":"en","type":"article","venue":"Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Genetics; Mendelian inheritance; Loss of heterozygosity; Ploidy; Gene; Allele; Genome; Genotype; Phenotype","score_opus":0.005337264669275664,"score_gpt":0.25205948884392,"score_spread":0.24672222417464432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053461321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97427994,0.00087199337,0.02352117,0.000030969764,0.000112854934,0.00012473756,0.000016978782,0.0000071572276,0.0010341944],"genre_scores_gemma":[0.99740267,0.00014217259,0.0020242864,0.000078583296,0.00013252858,0.0000044697003,0.00006138871,0.000019119007,0.00013479158],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99903727,0.000010572722,0.00027559197,0.00026004435,0.000096443626,0.0003201041],"domain_scores_gemma":[0.99948037,0.000008983728,0.000051314637,0.0003367912,0.000040905183,0.00008163944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025583195,0.00013388814,0.00016374512,0.000091624286,0.000022841657,0.000005491882,0.00019952483,0.000116537056,0.000019726544],"category_scores_gemma":[0.000020478994,0.00014485308,0.000060695766,0.00014744821,0.000038081005,0.0000023080504,0.0000861324,0.00008234848,0.000011808309],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019672141,0.000037741727,0.01619509,0.00003798618,0.000019110614,0.00001592947,0.000090596564,0.0007181727,0.9827079,0.0000073356096,0.0000039433535,0.00014648204],"study_design_scores_gemma":[0.00041371695,0.00012228603,0.7258017,0.0000064196456,0.0000072893085,0.000008731364,0.00004040771,0.0000037421803,0.2720527,0.00005903206,0.0012954562,0.00018850202],"about_ca_topic_score_codex":0.00010185404,"about_ca_topic_score_gemma":0.00013203672,"teacher_disagreement_score":0.7106553,"about_ca_system_score_codex":0.00002610076,"about_ca_system_score_gemma":0.00002537815,"threshold_uncertainty_score":0.5906938},"labels":[],"label_agreement":null},{"id":"W2054004034","doi":"10.1007/s00217-004-0921-6","title":"Detection and identification of transgenic virus resistant papaya and squash by multiplex PCR","year":2004,"lang":"en","type":"article","venue":"European Food Research and Technology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Papaya ringspot virus; Biology; Squash; Virology; Potyvirus; Gene; Zucchini yellow mosaic virus; Virus; Cucumber mosaic virus; Multiplex; Primer (cosmetics); Transgene; Plant virus; Genetics; Botany; Chemistry","score_opus":0.015439048756761194,"score_gpt":0.29835448189671376,"score_spread":0.28291543313995254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054004034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902305,0.006419717,0.0028736026,0.0001722839,0.000015356643,0.00013969764,0.000018960996,0.0000189502,0.00011090626],"genre_scores_gemma":[0.9976083,0.0021597436,0.00012071867,0.0000034845352,0.00001854652,0.000006946299,0.00000880694,0.00001581977,0.000057612375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999277,0.000046056768,0.00015001601,0.00026684476,0.00008026169,0.00017985076],"domain_scores_gemma":[0.9996652,0.00000808165,0.000025214043,0.00018296698,0.000065584994,0.00005297297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033055965,0.000075440905,0.00007750979,0.00013847741,0.00008967096,0.000016187185,0.000081850885,0.00008449168,7.4916704e-7],"category_scores_gemma":[0.000087557215,0.00007393479,0.000011568387,0.00015235433,0.0002936789,0.000002851999,0.00009852462,0.00013295714,0.0000010453514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004499574,0.0000253298,0.00009549705,0.00003353518,0.000019071202,0.0000011747313,0.000034797085,0.0000023956914,0.98560953,0.00011644793,0.000015667027,0.014001585],"study_design_scores_gemma":[0.0006099235,0.0013087394,0.0028410996,0.0000103545835,0.000004634655,0.00001543676,0.00012087581,0.000010809192,0.99163264,0.0004115174,0.0029586318,0.00007535002],"about_ca_topic_score_codex":0.000012613425,"about_ca_topic_score_gemma":0.000099689365,"teacher_disagreement_score":0.013926235,"about_ca_system_score_codex":0.0000049023265,"about_ca_system_score_gemma":0.000009490469,"threshold_uncertainty_score":0.3014973},"labels":[],"label_agreement":null},{"id":"W2055764090","doi":"10.1016/s0027-5107(00)00058-0","title":"Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue® rats","year":2000,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Cancer Center","keywords":"Transgene; Lac repressor; Gene; Genetics; Mutagen; Mutagenesis; Mutation; Molecular biology; Biology; Indel; Single-nucleotide polymorphism; Gene expression; lac operon; Carcinogen; Genotype","score_opus":0.0429567018573021,"score_gpt":0.35639637455827927,"score_spread":0.31343967270097717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055764090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96876556,0.0014722701,0.029027794,0.000054272903,0.000029058465,0.00031915985,0.00030065703,0.000002494073,0.000028747801],"genre_scores_gemma":[0.9975035,0.0003122399,0.0016974489,0.000018623892,0.00002195436,0.00002787666,0.00039717145,0.000014683245,0.000006492217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998309,0.00025834155,0.00047568168,0.00031228745,0.00049370783,0.00015098548],"domain_scores_gemma":[0.9993807,0.00013874398,0.000129764,0.00017316245,0.00012812912,0.000049488524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030600774,0.00015566115,0.00027285566,0.00018158181,0.000044099892,0.000014362074,0.00015024688,0.000099078454,0.000078392004],"category_scores_gemma":[0.000034253193,0.0001355954,0.000097595184,0.00018727573,0.00016339224,0.000009306238,0.000037984977,0.000073383824,3.0134828e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003478346,0.00019266708,0.00027054487,0.0000708185,0.00014264858,0.000008459244,0.0011279543,0.0025308807,0.98297286,0.00014466445,0.0000013518368,0.012189294],"study_design_scores_gemma":[0.0007585614,0.00047175723,0.023466833,0.000049647333,0.000059846967,0.0000046281743,0.0024679853,0.0024832534,0.9681691,0.0019548014,0.0000048697393,0.00010870028],"about_ca_topic_score_codex":0.000731949,"about_ca_topic_score_gemma":0.00019762765,"teacher_disagreement_score":0.028737962,"about_ca_system_score_codex":0.000013120551,"about_ca_system_score_gemma":0.000050264454,"threshold_uncertainty_score":0.552942},"labels":[],"label_agreement":null},{"id":"W2055797947","doi":"10.1073/pnas.252499499","title":"Air pollution induces heritable DNA mutations","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":211,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Health Canada","funders":"","keywords":"Germline mutation; Wildlife; Pollution; Biology; Mutation; Germline; DNA damage; Zoology; Genetics; DNA; Ecology; Gene","score_opus":0.026696127848899832,"score_gpt":0.30789198320733974,"score_spread":0.2811958553584399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055797947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99180853,0.00036853293,0.000010327348,0.0017068699,0.000015214151,0.000059371032,0.000006987174,0.0000037901993,0.0060203806],"genre_scores_gemma":[0.9985477,0.000039059647,0.00087054266,0.00015314264,0.000067564964,0.000004309197,1.8599042e-7,0.0000022611903,0.0003152594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993919,0.0000017189494,0.00012436004,0.00011780107,0.00028183102,0.00008235439],"domain_scores_gemma":[0.9997947,0.0000062279155,0.000087150795,0.0000050091944,0.000090429276,0.000016468673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002249212,0.00004624114,0.000048973412,0.000045864974,0.000094079136,0.0000063805023,0.00024913598,0.00005200522,0.0000101818005],"category_scores_gemma":[0.00014843732,0.000034710065,0.00003771048,0.00024880562,0.00021277732,0.000012839582,0.000052630054,0.00004265214,8.184183e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000011932171,0.000015395739,0.00039349528,0.000011169033,0.000005842662,5.342481e-10,0.000045938927,0.0010531106,0.9954094,0.0017653683,0.0010714622,0.00022759532],"study_design_scores_gemma":[0.00007074723,0.00003210105,0.020371743,0.000013985875,0.000004332844,0.0000043309547,0.000096847034,0.00052420585,0.97575307,0.0018424017,0.0012389816,0.00004728316],"about_ca_topic_score_codex":0.0000016168451,"about_ca_topic_score_gemma":4.5435602e-8,"teacher_disagreement_score":0.019978248,"about_ca_system_score_codex":0.000005465669,"about_ca_system_score_gemma":0.000006516315,"threshold_uncertainty_score":0.14154354},"labels":[],"label_agreement":null},{"id":"W2055846760","doi":"10.1089/clo.2006.0082","title":"The Kinetics of Donor Cell mtDNA in Embryonic and Somatic Donor Cell-Derived Bovine Embryos","year":2007,"lang":"en","type":"article","venue":"Cloning and Stem Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Heteroplasmy; Blastomere; Biology; Zygote; Somatic cell; Embryo; Mitochondrial DNA; Blastocyst; Embryonic stem cell; Molecular biology; Genetics; Cleavage (geology); Andrology; Embryogenesis; Gene","score_opus":0.005093210650289351,"score_gpt":0.2349549674537808,"score_spread":0.22986175680349147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055846760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842867,0.009483768,0.0050614825,0.00003078681,0.0001271314,0.00015613815,0.0000038711564,0.000006859881,0.00084323436],"genre_scores_gemma":[0.996886,0.0012087834,0.00063502125,0.000020699901,0.00005750137,0.000004302744,0.000004734167,0.000019191137,0.001163778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991123,0.000026593541,0.00027528848,0.00023149353,0.00007401109,0.00028033086],"domain_scores_gemma":[0.9995227,0.000075200616,0.00008006407,0.00021423837,0.000028578621,0.00007924242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002722993,0.00015248291,0.00016857477,0.00003944244,0.000060666738,0.00002689875,0.000107569394,0.00010973878,0.0000015205437],"category_scores_gemma":[0.000007708385,0.00012371075,0.00003987472,0.000067219546,0.00007558204,0.0000020830391,0.00008913252,0.00009466475,0.0000010668892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004405358,0.000029578145,0.0010926486,0.00014285566,0.000007996619,0.0000032694531,0.00022392794,0.00018978519,0.9962364,0.000011258323,0.00006157869,0.0019566356],"study_design_scores_gemma":[0.00065864745,0.0002965129,0.0031811234,0.000036033085,0.00001757724,0.000007060539,0.00062009733,0.0005007819,0.9923667,0.0000069555203,0.002151878,0.00015666832],"about_ca_topic_score_codex":0.000015392881,"about_ca_topic_score_gemma":0.00004917612,"teacher_disagreement_score":0.01259926,"about_ca_system_score_codex":0.0000071084564,"about_ca_system_score_gemma":0.00001534357,"threshold_uncertainty_score":0.5044778},"labels":[],"label_agreement":null},{"id":"W2056590801","doi":"10.1038/ncomms5399","title":"Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Biology; DNA; Palindrome; Homologous recombination; Genetics; Gene; Acquired immune system; Homologous chromosome; Trans-activating crRNA; Virology; Computational biology; Immune system","score_opus":0.010338395634802402,"score_gpt":0.31419815397647016,"score_spread":0.3038597583416678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056590801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97402006,0.006075904,0.013619632,0.002404813,0.00029393536,0.00035185725,0.00012635186,0.000040647283,0.0030667826],"genre_scores_gemma":[0.99543333,0.0006311211,0.0025932228,0.00019373397,0.000061726794,0.00003788788,0.0009791419,0.000015348187,0.000054475797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993787,0.000151991,0.00013198782,0.00014643821,0.00006105348,0.00012986157],"domain_scores_gemma":[0.9989221,0.00005521048,0.000041403386,0.0008709444,0.00007046482,0.000039876963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014567877,0.0001022291,0.000093246425,0.000041962347,0.000105284475,0.000018439048,0.0004425674,0.00023128286,0.000006744322],"category_scores_gemma":[0.00021490185,0.000111376845,0.00004334441,0.00010189216,0.000053342763,0.0000036056572,0.00018352826,0.00037766583,0.0000016785202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027823568,0.00014132049,0.0035384162,0.000008787861,0.00004268127,1.6617187e-7,0.00071609,0.00063983555,0.98493326,0.000598465,0.0050694663,0.0042836866],"study_design_scores_gemma":[0.0017878312,0.0002883441,0.09909955,0.000037076647,0.000058222988,0.0000104220035,0.0007560271,0.0063113295,0.5054729,0.0001755908,0.38534397,0.0006587262],"about_ca_topic_score_codex":0.00016028836,"about_ca_topic_score_gemma":0.0049717096,"teacher_disagreement_score":0.47946036,"about_ca_system_score_codex":0.000024154326,"about_ca_system_score_gemma":0.000028265003,"threshold_uncertainty_score":0.45418158},"labels":[],"label_agreement":null},{"id":"W2056800028","doi":"10.1007/s11627-000-0060-0","title":"DNA shuffling: Modifying the hand that nature dealt","year":2000,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Plant","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNA shuffling; Shuffling; Homologous recombination; Gene; Genetics; Biology; DNA; Polymerase chain reaction; Genome; Computational biology; Recombination; Directed evolution; Genetic recombination; Operon; Mutant; Computer science","score_opus":0.009029096785222446,"score_gpt":0.25178799297785925,"score_spread":0.2427588961926368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056800028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993914,0.004016601,0.00055800774,0.00013385534,0.000247219,0.00019795213,0.000065854816,0.000015811162,0.00085067714],"genre_scores_gemma":[0.99644184,0.0004254932,0.0011698256,0.0004658661,0.00012406468,0.00003022615,0.0010070937,0.000021378635,0.00031423735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987802,0.000058585305,0.0002302931,0.00041126646,0.00008831592,0.00043137022],"domain_scores_gemma":[0.99965626,0.000021537324,0.000035934583,0.00020795738,0.000011334333,0.00006698174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022222433,0.00023132248,0.0001807466,0.000052216386,0.00015744944,0.000027995704,0.0003051,0.0003788743,0.00007319285],"category_scores_gemma":[0.00001510505,0.0001760193,0.000066619294,0.00008665589,0.000117326344,0.0000031537954,0.000098048884,0.0003221315,0.000029069995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014447415,0.000026528613,0.002858109,0.000009157923,0.000042736152,0.000025090769,0.00017404815,0.000099591125,0.99150836,0.000013174298,0.00023535536,0.004863397],"study_design_scores_gemma":[0.00044744348,0.000040083483,0.0016237375,0.000013546863,0.0000075968887,0.00009893087,0.000107483334,0.00018284205,0.9183345,0.000040254217,0.0788545,0.00024912148],"about_ca_topic_score_codex":0.00003978716,"about_ca_topic_score_gemma":0.00005821045,"teacher_disagreement_score":0.078619145,"about_ca_system_score_codex":0.000031961074,"about_ca_system_score_gemma":0.000065071865,"threshold_uncertainty_score":0.71778584},"labels":[],"label_agreement":null},{"id":"W2059627150","doi":"10.1111/j.1600-0463.2006.apm_546.x","title":"Mendelian analysis of a metastasis‐prone substrain of BALB/c nude mice using a subcutaneously inoculated human tumour","year":2006,"lang":"en","type":"article","venue":"Apmis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre","funders":"","keywords":"Metastasis; Immunohistochemistry; Mendelian inheritance; Phenotype; Melanoma; Biology; Pathology; Cancer research; Experimental pathology; Mammary carcinoma; Nude mouse; Carcinoma; Cancer; In vivo; Immunology; Medicine; Gene; Genetics","score_opus":0.010323830150138196,"score_gpt":0.295847438607279,"score_spread":0.2855236084571408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059627150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931619,0.00071732776,0.0055350983,0.000010382816,0.000019348532,0.00008775981,0.00006468456,0.000008175579,0.00039528927],"genre_scores_gemma":[0.9968562,0.000013301716,0.0027715256,0.000009979899,0.00003496883,0.0000024127676,0.00020058913,0.000018714793,0.000092323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903744,0.000029524126,0.00036354017,0.00024132554,0.00013241754,0.00019575733],"domain_scores_gemma":[0.99947035,0.0000074023806,0.00012785567,0.00026329045,0.00008854833,0.00004252886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013059512,0.00014396352,0.00029934634,0.00017187098,0.000030974876,0.0000066567395,0.00013516711,0.00009236083,0.00003854741],"category_scores_gemma":[0.000013353957,0.00014941664,0.00021000163,0.0004515871,0.000049778173,0.0000018642161,0.000042334137,0.00004682182,4.8488164e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016382302,0.00005920838,0.0014517728,0.000029548615,0.0005897523,0.000006252443,0.000051945062,0.01935803,0.9781754,0.00003764738,0.000035923353,0.00018812943],"study_design_scores_gemma":[0.00028255171,0.00009194887,0.008224576,0.000010518737,0.0008363032,0.000015057479,0.00008618495,0.0031199518,0.9869763,0.000022028036,0.00016534723,0.00016918812],"about_ca_topic_score_codex":0.0012289255,"about_ca_topic_score_gemma":0.0005619991,"teacher_disagreement_score":0.016238078,"about_ca_system_score_codex":0.000010851126,"about_ca_system_score_gemma":0.000023824183,"threshold_uncertainty_score":0.60930336},"labels":[],"label_agreement":null},{"id":"W2059718902","doi":"10.1074/jbc.m301110200","title":"Evidence for a Role of MCM (Mini-chromosome Maintenance)5 in Transcriptional Repression of Sub-telomeric and Ty-proximal Genes in Saccharomyces cerevisiae","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Saccharomyces cerevisiae; Psychological repression; Gene; Genetics; Chromosome; Telomere; Biology; Gene expression","score_opus":0.026556748226795893,"score_gpt":0.3017844090445288,"score_spread":0.2752276608177329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059718902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.973949,0.025420893,0.0004555292,0.000027541291,0.000024305213,0.00007617884,0.000010200552,9.1797654e-7,0.00003541474],"genre_scores_gemma":[0.99397105,0.0042675724,0.0016748945,0.0000070627143,0.000055441928,0.00000622711,0.000004075939,0.0000052581368,0.000008411886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990891,0.000029611761,0.00048260752,0.00017171084,0.000082699866,0.00014423436],"domain_scores_gemma":[0.9995132,0.00005830112,0.00020226534,0.00009740374,0.00007951667,0.000049280567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568803,0.00010665392,0.0002853924,0.000031002095,0.000009196631,0.000003497443,0.00011971167,0.00015609736,0.000016662409],"category_scores_gemma":[0.00041203146,0.00008042941,0.0001059387,0.00007766345,0.00008070937,0.0000057112275,0.000023940729,0.0000992881,3.695054e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000255005,0.00006928182,0.025559392,0.00013725758,0.000013218847,0.000003020043,0.00002384459,0.00014461855,0.9720961,0.000008768952,0.000007125517,0.0016824094],"study_design_scores_gemma":[0.0006751122,0.00028472545,0.025398567,0.000271062,0.000008170753,0.000080062455,0.00014240683,0.000037459133,0.972453,0.00016737294,0.00039120932,0.00009083798],"about_ca_topic_score_codex":0.0000017778154,"about_ca_topic_score_gemma":0.0000010382206,"teacher_disagreement_score":0.021153321,"about_ca_system_score_codex":0.000011044296,"about_ca_system_score_gemma":0.000046177356,"threshold_uncertainty_score":0.32798162},"labels":[],"label_agreement":null},{"id":"W2059755265","doi":"10.1051/medsci/20082489703","title":"Quand les gènes s’éclatent","year":2008,"lang":"fr","type":"article","venue":"médecine/sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Geography; Political science","score_opus":0.0506714115404919,"score_gpt":0.3182877754998204,"score_spread":0.26761636395932853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059755265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8781255,0.10008312,0.008236625,0.0025743747,0.0013395583,0.00013296025,0.00001812131,0.000021527816,0.009468213],"genre_scores_gemma":[0.97797674,0.0076581626,0.0029706657,0.0001757737,0.0006341256,0.000008299673,0.000010138703,0.00001799687,0.010548126],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99840176,0.00004927222,0.00026995133,0.00052365416,0.00025071995,0.000504665],"domain_scores_gemma":[0.9994976,0.000033766722,0.00006010526,0.00023092085,0.00005116072,0.00012646892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028565747,0.0002449369,0.00020127025,0.00007183787,0.0005191226,0.00004318947,0.00034814724,0.00019635471,0.00017834177],"category_scores_gemma":[0.00007647747,0.00022484768,0.00013237193,0.00025809841,0.0009968687,0.000008110462,0.00013271518,0.00011041896,0.00005673128],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007567954,0.0008148155,0.307244,0.0002993589,0.00024170165,0.00014736947,0.000930992,0.035558272,0.52167183,0.0077093113,0.07555813,0.04974855],"study_design_scores_gemma":[0.0015490272,0.002115362,0.0721573,0.00016341022,0.00007937168,0.00081394456,0.0007034267,0.003763813,0.2506046,0.00053528644,0.66637313,0.0011413376],"about_ca_topic_score_codex":0.00020568552,"about_ca_topic_score_gemma":0.00007186314,"teacher_disagreement_score":0.590815,"about_ca_system_score_codex":0.000013734877,"about_ca_system_score_gemma":0.00013227259,"threshold_uncertainty_score":0.91690224},"labels":[],"label_agreement":null},{"id":"W2060297895","doi":"10.1038/nmeth.2641","title":"Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination","year":2013,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1066,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"CRISPR; Cas9; Caenorhabditis elegans; Homologous recombination; Biology; Genome editing; Genome; Genetics; Computational biology; Genome engineering; Gene; Homologous chromosome; Caenorhabditis","score_opus":0.007549201337362386,"score_gpt":0.35240374152641196,"score_spread":0.3448545401890496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060297895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5362944,0.007144987,0.4542365,0.00027408797,0.0010571604,0.00039589952,0.000008829883,0.00004472263,0.0005434079],"genre_scores_gemma":[0.8251352,0.00010752068,0.1735802,0.00017707294,0.00041181513,0.000036148656,0.000040530707,0.000039970742,0.00047159134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990791,0.000112427464,0.0001687158,0.00027241884,0.00009559174,0.0002717444],"domain_scores_gemma":[0.9993605,0.000056195666,0.000046350917,0.0003746481,0.00010072105,0.00006155847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044102583,0.00016810173,0.0001386146,0.000058983893,0.000091905735,0.00004486846,0.00022574922,0.0003684705,0.00005490724],"category_scores_gemma":[0.00028386276,0.00013444376,0.00009002685,0.00016787746,0.000025539985,0.000005273663,0.00007810032,0.00038294328,0.0000069269745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000027980584,0.000010676509,0.00004512466,0.0000143275865,0.000042693086,0.0000021283938,0.000051568404,0.0036108878,0.98320097,0.000067314584,0.00030581496,0.01264567],"study_design_scores_gemma":[0.0004859782,0.00012752245,0.012468436,0.000016432372,0.00006824423,0.0002749447,0.00008558208,0.015157311,0.88197875,0.00029847017,0.08848681,0.00055153295],"about_ca_topic_score_codex":0.000054943568,"about_ca_topic_score_gemma":0.000006140594,"teacher_disagreement_score":0.28884077,"about_ca_system_score_codex":0.000030039066,"about_ca_system_score_gemma":0.000028214328,"threshold_uncertainty_score":0.5482458},"labels":[],"label_agreement":null},{"id":"W2060708014","doi":"10.1128/jb.182.24.7060-7066.2000","title":"Sensitive Genetic Screen for Protease Activity Based on a Cyclic AMP Signaling Cascade in <i>Escherichia coli</i>","year":2000,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Institut national de la recherche scientifique","keywords":"Biology; Escherichia coli; Protease; Escherichia coli Proteins; Signal transduction; Cascade; Microbiology; Biochemistry; Genetics; Cell biology; Enzyme; Gene","score_opus":0.00941705394738661,"score_gpt":0.2749912889737783,"score_spread":0.26557423502639166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060708014","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9742826,0.00008374315,0.025025193,0.00016065215,0.00008353311,0.00026872018,0.00002116292,0.000003393822,0.00007098909],"genre_scores_gemma":[0.9926017,0.000047596994,0.0064669633,0.00045757997,0.00032126473,0.000016153523,0.000012337473,0.000022405522,0.000054005093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903643,0.00011850129,0.00032639713,0.00019587931,0.00007216818,0.00025062336],"domain_scores_gemma":[0.99949175,0.000051623596,0.00014216488,0.00015414077,0.000065115026,0.0000952047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002687917,0.00015570005,0.00027406888,0.00008268734,0.0000328692,0.0000111246,0.00010985187,0.00017015866,0.000029598968],"category_scores_gemma":[0.000087389446,0.00014474668,0.00014312027,0.000068917005,0.000040881096,0.000003672864,0.000013196046,0.00018583387,0.000002700958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013090997,0.000082196326,0.00059876987,0.000015959382,0.00003190507,0.000020735975,0.0000313831,0.025983984,0.96646327,4.296866e-7,0.00006667084,0.0053955913],"study_design_scores_gemma":[0.0026890284,0.002207817,0.060521994,0.00008179639,0.000042824442,0.00013199747,0.000018768287,0.0037894095,0.9156082,0.000018576242,0.014570816,0.00031874105],"about_ca_topic_score_codex":0.000018481654,"about_ca_topic_score_gemma":0.000024908491,"teacher_disagreement_score":0.059923224,"about_ca_system_score_codex":0.000026235179,"about_ca_system_score_gemma":0.00009950117,"threshold_uncertainty_score":0.5902598},"labels":[],"label_agreement":null},{"id":"W2062509850","doi":"10.1002/(sici)1097-4644(20000315)76:4<674::aid-jcb15>3.0.co;2-2","title":"Circular YAC vectors containing short mammalian origin sequences are maintained under selection as HeLa episomes","year":2000,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of British Columbia","funders":"Office of Research Infrastructure Programs, National Institutes of Health","keywords":"Biology; Plasmid; Molecular biology; Transfection; Ethidium bromide; Origin of replication; Transformation (genetics); Extrachromosomal DNA; DNA; Cloning vector; Vector (molecular biology); Gene; Genetics; Recombinant DNA","score_opus":0.007763339658855925,"score_gpt":0.2740691145844509,"score_spread":0.26630577492559493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062509850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98750085,0.0025861324,0.008780375,0.00013788605,0.00018009765,0.00007316736,0.00000533261,0.000014017175,0.00072212244],"genre_scores_gemma":[0.9966194,0.00026641253,0.00053993455,0.00011326102,0.0009507775,0.00000358663,0.000040610266,0.0000375616,0.0014284365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855626,0.000043719458,0.00046372524,0.00029494852,0.0002982188,0.00034315282],"domain_scores_gemma":[0.9992134,0.00001447386,0.00017112831,0.00023325987,0.000158705,0.00020902939],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031985674,0.00026095012,0.00028317596,0.00006445211,0.000094308685,0.00005441913,0.00026664668,0.0002708842,0.00027492974],"category_scores_gemma":[0.00007199093,0.00025583562,0.0002534146,0.00015396094,0.000074060925,0.000009396189,0.000028558596,0.00026699845,0.000008988608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010957976,0.00004331764,0.0022698343,0.00004626199,0.00014804934,0.000059082886,0.00002650928,0.002589408,0.99352175,0.000008180448,0.00033718193,0.0008408706],"study_design_scores_gemma":[0.00042084104,0.00028583955,0.00047456243,0.000083469466,0.000068015805,0.0004459938,0.00037714062,0.00006498782,0.9915121,0.00009027303,0.0058746003,0.0003021423],"about_ca_topic_score_codex":0.000012183072,"about_ca_topic_score_gemma":0.0000031243435,"teacher_disagreement_score":0.00911855,"about_ca_system_score_codex":0.000076775395,"about_ca_system_score_gemma":0.00018271024,"threshold_uncertainty_score":0.9999894},"labels":[],"label_agreement":null},{"id":"W2062593333","doi":"10.1097/00005176-200410000-00031","title":"Powerful New Genetic Tools May Unlock Old Mysteries","year":2004,"lang":"en","type":"letter","venue":"Journal of Pediatric Gastroenterology and Nutrition","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bishop's University","funders":"","keywords":"Medicine; Computational biology; Evolutionary biology; Biology","score_opus":0.007616480723388078,"score_gpt":0.24895628137264647,"score_spread":0.2413398006492584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062593333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8928925,0.015589351,0.01261184,0.0767464,0.0017474976,0.00030908306,0.00006823609,0.0000107863625,0.00002434468],"genre_scores_gemma":[0.5666197,0.057882946,0.017538067,0.23638235,0.118069515,0.000028582232,0.00085671555,0.00025909283,0.0023630492],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99856615,0.00007392711,0.0005534257,0.00027227393,0.00017694221,0.000357302],"domain_scores_gemma":[0.99916595,0.000017861024,0.00039425137,0.00018966138,0.000115081275,0.00011721305],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011467682,0.00028891175,0.00039760274,0.00023365646,0.000039104398,0.000043065615,0.00020463577,0.0006769388,0.000021386084],"category_scores_gemma":[0.00003949501,0.00028057775,0.00021042475,0.000054485543,0.000053486445,0.000009539044,0.00006920617,0.00072314864,0.0000035860523],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066097535,0.00009844259,0.0124391075,0.00053735106,0.00020667292,0.00047703792,0.000046279343,0.0001469652,0.003540791,9.0658705e-7,0.9814656,0.00037991736],"study_design_scores_gemma":[0.015361022,0.023626527,0.044333767,0.00044012285,0.002179318,0.017258111,0.00011211948,0.000009483974,0.0056152474,0.0007823283,0.88904536,0.0012366116],"about_ca_topic_score_codex":0.0000043257196,"about_ca_topic_score_gemma":0.000004314747,"teacher_disagreement_score":0.3262728,"about_ca_system_score_codex":0.000025775074,"about_ca_system_score_gemma":0.000089798465,"threshold_uncertainty_score":0.99996465},"labels":[],"label_agreement":null},{"id":"W2063151474","doi":"10.1016/j.bbagen.2005.02.007","title":"PCR-based unidirectional deletion method for creation of comprehensive cDNA libraries","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Complementary DNA; cDNA library; Computational biology; Genomic library; Biology; DNA; Insert (composites); Restriction enzyme; DNA sequencing; Molecular biology; Genetics; Computer science; Gene; Base sequence; Engineering","score_opus":0.013542320305304433,"score_gpt":0.3132921389146547,"score_spread":0.29974981860935024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063151474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93856454,0.0003322048,0.05952144,0.00070664444,0.00016545625,0.00034208095,0.00011286237,0.00004109448,0.00021366477],"genre_scores_gemma":[0.92051744,0.00007995777,0.07705039,0.00041629956,0.00072405016,0.000063082545,0.00089987746,0.000043505217,0.00020541556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987531,0.000083693696,0.00029372107,0.00043138687,0.0001665997,0.00027154144],"domain_scores_gemma":[0.99923146,0.00005959886,0.00014550735,0.0003028282,0.00017317249,0.00008742728],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000100550635,0.00025802306,0.00025049393,0.00009549821,0.00009492509,0.000034084165,0.00017242474,0.00017918789,0.000010617275],"category_scores_gemma":[0.000035014134,0.00026235761,0.00022423432,0.00016544224,0.0000778453,0.0000136409735,0.000058167745,0.00007958582,0.0000024292624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025552997,0.000116047115,0.0000071344057,0.00005161021,0.00008877133,1.5852439e-7,0.000046643076,0.0047076945,0.9909582,0.00036918043,0.0015103737,0.001888664],"study_design_scores_gemma":[0.0007967817,0.00037661832,0.002340673,0.000018081058,0.000055542983,0.000003334523,0.00002087879,0.009329764,0.9776113,0.000078177174,0.0090783015,0.00029053513],"about_ca_topic_score_codex":0.000029462013,"about_ca_topic_score_gemma":0.000018025581,"teacher_disagreement_score":0.018047132,"about_ca_system_score_codex":0.000022305669,"about_ca_system_score_gemma":0.00013187593,"threshold_uncertainty_score":0.99998283},"labels":[],"label_agreement":null},{"id":"W2063764609","doi":"10.1016/j.bbaexp.2005.08.011","title":"A new alternative splice variant of BRCA1 containing an additional in-frame exon","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Québec; Hôpital du Sacré-Cœur de Montréal; Cégep de Rimouski; Cégep de Jonquière; Université Laval; Alberta Children's Hospital; Hôpital du Saint-Sacrement; Centre Hospitalier Universitaire de Sherbrooke; Centre hospitalier universitaire de Québec","funders":"","keywords":"Exon; Alternative splicing; Biology; RNA splicing; Intron; Gene; Genetics; splice; Transcription (linguistics); Molecular biology; RNA","score_opus":0.006206716876269971,"score_gpt":0.2742030615760878,"score_spread":0.26799634469981787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063764609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971129,0.00026948366,0.0017190757,0.00013987679,0.00008127833,0.00014480656,0.0004051047,0.000011713393,0.00011577368],"genre_scores_gemma":[0.9848298,0.00018532596,0.013246574,0.000167143,0.00069601537,0.000008023025,0.00080468884,0.000026488571,0.000035948586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988612,0.000046455796,0.0002543329,0.0004529027,0.0001562639,0.0002288715],"domain_scores_gemma":[0.99937767,0.000020922991,0.00012158923,0.00029907367,0.000042341555,0.00013841683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053370215,0.00023568353,0.00022136218,0.00007293566,0.00004877642,0.000020313011,0.00018607674,0.00017327981,0.00010129121],"category_scores_gemma":[0.000022425607,0.00021085356,0.00006411532,0.000084219,0.000046690213,0.000019288555,0.000133893,0.00014681337,8.1419194e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018475662,0.00003705968,0.0000055649084,0.000014326837,0.00002902145,0.0000018203157,0.0004890908,0.00039161986,0.9959685,0.000038622944,0.0007493546,0.0020902178],"study_design_scores_gemma":[0.0007249981,0.00030011736,0.0037323267,0.00006918983,0.00001655694,0.000022319973,0.00008245631,0.00053633185,0.9926721,0.00019979129,0.0013921196,0.00025169548],"about_ca_topic_score_codex":0.000045086337,"about_ca_topic_score_gemma":0.0000286494,"teacher_disagreement_score":0.012283094,"about_ca_system_score_codex":0.000011042269,"about_ca_system_score_gemma":0.00006624647,"threshold_uncertainty_score":0.85983586},"labels":[],"label_agreement":null},{"id":"W2063853502","doi":"10.1242/dev.114488","title":"Tissue-specific genome editing in <i>Ciona</i> embryos by CRISPR/Cas9","year":2014,"lang":"en","type":"article","venue":"Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; York University; American Heart Association; National Science Foundation","keywords":"CRISPR; Ciona; Biology; Ciona intestinalis; Cas9; Genome editing; Electroporation; Zebrafish; Gene; Genetics; Gene knockout; Genome; Computational biology; Cell biology","score_opus":0.005497049869607241,"score_gpt":0.24981197362332896,"score_spread":0.2443149237537217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063853502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8025588,0.0031438202,0.18819161,0.0002724639,0.0006058868,0.00026992688,0.000008737691,0.000039576164,0.0049092206],"genre_scores_gemma":[0.99098015,0.00011484779,0.007227107,0.00022260193,0.00030592427,0.000036459725,0.00018818707,0.000026336718,0.00089836156],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990541,0.000018543486,0.00022805663,0.0002992782,0.00012118182,0.0002788898],"domain_scores_gemma":[0.9996786,0.0000067153405,0.000030774852,0.00018503111,0.00002598611,0.00007285745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002071087,0.00014292188,0.000115086325,0.000042427353,0.0000497758,0.000018491552,0.0001396308,0.00008799308,0.00003459842],"category_scores_gemma":[0.00002039546,0.00015314667,0.000021174112,0.000069457616,0.00001518106,0.000001918534,0.00008699869,0.00007416698,0.000050017912],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006839853,0.000032505937,0.00060781464,0.000018366649,0.0000110529,0.000002584566,0.00019457073,0.00027758584,0.96528643,0.000028877872,0.009526892,0.024006482],"study_design_scores_gemma":[0.00019385702,0.000020440002,0.003852862,0.0000070805945,8.479302e-7,0.0000037123095,0.000031353535,0.000014401593,0.41621557,0.0000046131368,0.5795208,0.00013444676],"about_ca_topic_score_codex":0.0000033443735,"about_ca_topic_score_gemma":0.000015208667,"teacher_disagreement_score":0.5699939,"about_ca_system_score_codex":0.000025700501,"about_ca_system_score_gemma":0.000026009273,"threshold_uncertainty_score":0.62451404},"labels":[],"label_agreement":null},{"id":"W2064299980","doi":"10.1385/mb:30:2:095","title":"Successive Chromosome Walking by Compatible Ends Ligation Inverse PCR","year":2005,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Inverse polymerase chain reaction; Ligation; Biology; Molecular biology; Polymerase chain reaction; DNA; Restriction enzyme; Chromosome; Genetics; Nested polymerase chain reaction; Gene","score_opus":0.0036570043107545572,"score_gpt":0.2531380950578475,"score_spread":0.24948109074709296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064299980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83819616,0.0022619169,0.15696065,0.0016326834,0.00011862536,0.00016881722,0.00001754555,0.000112937836,0.0005306418],"genre_scores_gemma":[0.9937667,0.00018559908,0.0049388562,0.00048496143,0.00010349263,0.000026450944,0.000209347,0.000037840997,0.00024671818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988466,0.000027838363,0.00021851898,0.00043389635,0.00011800061,0.00035514732],"domain_scores_gemma":[0.9993388,0.0000058441165,0.00007275611,0.00046818913,0.000042279353,0.000072097406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008452489,0.00021049676,0.00016966026,0.00011877643,0.00007107014,0.00002088149,0.0002935176,0.00047999487,0.000035024103],"category_scores_gemma":[0.00006350342,0.00023387944,0.00008169983,0.00019987886,0.00011243537,0.0000049228333,0.00017202216,0.00018492798,0.00004101594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008233455,0.00003683426,0.00007281145,0.0000098691435,0.00003991075,0.000008083074,0.000020858588,0.00086299906,0.9826762,0.00034381775,0.0019680187,0.013952358],"study_design_scores_gemma":[0.00040201575,0.00015117503,0.000027854425,0.000009437924,0.000015118626,0.000025668189,0.000030651878,0.0011003284,0.90792847,0.000044857814,0.09002027,0.00024415925],"about_ca_topic_score_codex":0.000015477983,"about_ca_topic_score_gemma":0.000034580677,"teacher_disagreement_score":0.15557055,"about_ca_system_score_codex":0.000027414204,"about_ca_system_score_gemma":0.00002708644,"threshold_uncertainty_score":0.95373267},"labels":[],"label_agreement":null},{"id":"W2064689304","doi":"10.1007/s00438-005-1112-2","title":"Characterization of in vivo recombination activities in the mouse embryo","year":2005,"lang":"en","type":"article","venue":"Molecular Genetics and Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Homologous recombination; Biology; Non-allelic homologous recombination; FLP-FRT recombination; Homologous chromosome; Recombination; Genetics; Transgene; Homology (biology); Genetic recombination; Ectopic recombination; Genetically modified mouse; Molecular biology; Plasmid; Gene; Embryo; Site-specific recombination; Gene targeting; DNA; Recombinase","score_opus":0.00430976665799229,"score_gpt":0.23360671891421958,"score_spread":0.2292969522562273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064689304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945234,0.00061752816,0.004421594,0.00011650501,0.000022549824,0.00015417776,0.000013251916,0.0000017921955,0.00012916914],"genre_scores_gemma":[0.9979295,0.0011200875,0.00067389244,0.00012741552,0.000034253797,0.000011642972,0.0000426288,0.000013342556,0.000047251466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994576,0.00003381886,0.00017483783,0.0001518753,0.00006236212,0.00011948874],"domain_scores_gemma":[0.99975145,0.000004574162,0.000040991712,0.00017056806,0.000014946601,0.00001748457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015082101,0.00008931565,0.0000876488,0.00006462524,0.000015253728,0.000014886684,0.000097727236,0.00007434688,0.000002698537],"category_scores_gemma":[0.0000083429095,0.00008643741,0.000025952204,0.0000679892,0.000025378806,0.0000022726117,0.00004027702,0.000052202886,2.986715e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000105432,0.000037208865,0.001005013,0.0000105016225,0.0000051227426,7.854099e-7,0.0002870412,0.003125159,0.99168223,0.000061809966,0.0000064038227,0.0037681602],"study_design_scores_gemma":[0.00033005944,0.00006834737,0.011697353,0.000004331937,0.000004971075,0.000004651776,0.000109232904,0.0017519272,0.9813485,0.000042871674,0.0045309854,0.00010676135],"about_ca_topic_score_codex":0.000007326652,"about_ca_topic_score_gemma":0.000091243586,"teacher_disagreement_score":0.010692339,"about_ca_system_score_codex":0.000010431018,"about_ca_system_score_gemma":0.0000173275,"threshold_uncertainty_score":0.35248154},"labels":[],"label_agreement":null},{"id":"W2064849217","doi":"10.1063/1.1350441","title":"Molecular, metabolic, and genetic control: An introduction","year":2001,"lang":"en","type":"article","venue":"Chaos An Interdisciplinary Journal of Nonlinear Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Computational biology; Biology; Control (management); Genetics; Evolutionary biology; Computer science; Artificial intelligence","score_opus":0.007369290467176804,"score_gpt":0.3283676269141815,"score_spread":0.32099833644700465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064849217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94098294,0.0011704898,0.056772828,0.000581416,0.0003836277,0.0000624305,0.0000030458893,0.000005102471,0.000038143724],"genre_scores_gemma":[0.98978937,0.00022282962,0.008619627,0.00007124035,0.0012541059,0.0000013736384,0.000003451879,0.000014884171,0.000023115663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989228,0.00003522442,0.00029252074,0.00029763574,0.00022161205,0.00023018279],"domain_scores_gemma":[0.9990702,0.0000036922927,0.00012325546,0.00029683104,0.0002540743,0.0002519205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042470652,0.00013260974,0.00016813952,0.00015870998,0.00016193601,0.00007223335,0.00037008346,0.00005215098,0.00001225887],"category_scores_gemma":[0.000043438584,0.000113812035,0.000060699036,0.00018105982,0.00027575684,0.000045015775,0.00019390548,0.00012250057,9.4753887e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012017707,0.000093378745,0.0010160746,0.000004410197,0.000018344224,0.000047795224,0.00020744331,0.0058304574,0.97937673,0.000035822344,0.000028611974,0.013220737],"study_design_scores_gemma":[0.0034338709,0.008512066,0.10212777,0.000057831418,0.00018753724,0.016199555,0.002121292,0.09174066,0.7578823,0.0006141694,0.016078439,0.0010445167],"about_ca_topic_score_codex":0.0000011502259,"about_ca_topic_score_gemma":0.0000061246296,"teacher_disagreement_score":0.22149447,"about_ca_system_score_codex":0.000009884883,"about_ca_system_score_gemma":0.00008145783,"threshold_uncertainty_score":0.464112},"labels":[],"label_agreement":null},{"id":"W2065138915","doi":"10.1098/rsbl.2006.0444","title":"An analytical model assessing the potential threat to natural habitats from insect resistance transgenes: continuous transgene input","year":2006,"lang":"en","type":"article","venue":"Biology Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Burnaby Hospital; Simon Fraser University","funders":"","keywords":"Biology; Transgene; Resistance (ecology); Insect; Habitat; Ecology; Biotechnology; Gene; Genetics","score_opus":0.00977728046120535,"score_gpt":0.2963576321861615,"score_spread":0.28658035172495616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065138915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7034597,0.0010818602,0.29351914,0.0015220974,0.00018076849,0.00012126078,0.000048481754,0.000021505122,0.00004518741],"genre_scores_gemma":[0.9930299,0.000016726426,0.003920607,0.0020535009,0.0005415449,0.00001923835,0.0003285444,0.000028094486,0.00006184327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987112,0.00010355962,0.0002402333,0.0004894548,0.00008779151,0.0003677252],"domain_scores_gemma":[0.9994459,0.000021988431,0.000032699405,0.0003919468,0.000034250923,0.00007320323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014425324,0.00022185645,0.00020230359,0.00004260492,0.00012198643,0.000047829268,0.00031095638,0.00016417686,0.00000475992],"category_scores_gemma":[0.0000128347665,0.00017283816,0.00012732693,0.000084058694,0.00013314871,0.0000063272637,0.000025062633,0.00013749911,0.0000027715996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065635446,0.000025854573,0.0014415821,0.0000035326568,0.00004507549,0.0000066474827,0.000052576786,0.02426546,0.97235,0.000047793394,0.0010344739,0.0006613729],"study_design_scores_gemma":[0.002189543,0.00032633223,0.10522787,0.00003940448,0.0002522836,0.000032340657,0.00018913529,0.05142228,0.8319661,0.0005321314,0.0063909595,0.0014315937],"about_ca_topic_score_codex":0.00009489038,"about_ca_topic_score_gemma":0.00032826478,"teacher_disagreement_score":0.28959855,"about_ca_system_score_codex":0.000015354939,"about_ca_system_score_gemma":0.000029078428,"threshold_uncertainty_score":0.7048136},"labels":[],"label_agreement":null},{"id":"W2065417035","doi":"10.1021/ac901445b","title":"Affinity Sensing for Transgenes Detection in Antidoping Control","year":2009,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Università degli Studi di Firenze; Ministero della Salute; World Anti-Doping Agency","keywords":"Oligonucleotide; Chemistry; Transgene; Gene; Plasmid; DNA; Computational biology; Molecular biology; Biosensor; Green fluorescent protein; Genetic enhancement; Biochemistry; Biology","score_opus":0.007890126770130379,"score_gpt":0.29562121680127196,"score_spread":0.28773109003114156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065417035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82241136,0.0001841754,0.17649601,0.00014971478,0.000032553533,0.0000836641,0.0000042756865,0.0000129718765,0.0006252672],"genre_scores_gemma":[0.9990616,0.000020808448,0.00046649942,0.000119087796,0.00022014369,0.0000020929754,0.000015265921,0.000008316619,0.000086229724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936974,0.0000060978596,0.00015077712,0.00021787747,0.000052411197,0.00020308878],"domain_scores_gemma":[0.9997462,0.000015443093,0.000017032206,0.00013466484,0.00003073183,0.00005593946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009264807,0.000101728336,0.0001220575,0.000014697484,0.000029476827,0.000012770464,0.000055084005,0.00012418003,0.0000042997317],"category_scores_gemma":[0.00008380176,0.00010982469,0.000089995636,0.00006252729,0.000017913808,0.0000016371347,0.000005490096,0.00006810543,5.94751e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005446959,0.000020085672,0.00017851459,0.000026106252,0.000012544373,0.0000018481805,0.0000054996276,0.0010664528,0.9918047,0.000003965849,0.000031560197,0.0067942566],"study_design_scores_gemma":[0.0007075882,0.000056820107,0.0018959477,0.000013236424,0.000020577732,0.000008315642,0.000018283854,0.020524127,0.9753144,0.0000680426,0.0012239161,0.00014875851],"about_ca_topic_score_codex":0.0000036299264,"about_ca_topic_score_gemma":0.000010022518,"teacher_disagreement_score":0.1766502,"about_ca_system_score_codex":0.000010974532,"about_ca_system_score_gemma":0.00001616651,"threshold_uncertainty_score":0.44785208},"labels":[],"label_agreement":null},{"id":"W2065807820","doi":"10.1016/j.dnarep.2007.05.006","title":"Erratum to “Analysis of DNA repair and recombination responses in mouse cells depleted for Brca2 by SiRNA” [DNA Repair 6 (2007) 809–817]","year":2007,"lang":"en","type":"erratum","venue":"DNA repair","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; DNA repair; DNA; Genetics; DNA mismatch repair; Molecular biology; Cell biology","score_opus":0.00846125872279445,"score_gpt":0.2835633904962618,"score_spread":0.2751021317734673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065807820","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9558414,0.01712523,0.005898972,0.00036420792,0.00905332,0.0034362082,0.0025770809,0.00090620783,0.004797326],"genre_scores_gemma":[0.27379635,0.00643978,0.024420254,0.0020744181,0.0023607914,0.0009075425,0.019890314,0.0009688903,0.66914165],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99618524,0.00017035588,0.0011457959,0.0014013561,0.0003858948,0.0007113336],"domain_scores_gemma":[0.9975986,0.00013829976,0.00036384887,0.0012935563,0.00033982555,0.00026587673],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013444393,0.000638485,0.0010298186,0.0009817469,0.00009516054,0.00003143992,0.00033187622,0.0012183933,0.000023752475],"category_scores_gemma":[0.0008702285,0.0007151166,0.0010065614,0.00086007727,0.00009273298,0.00001141693,0.00021602752,0.00040898754,0.0000027634221],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004855358,0.00017402672,0.000408618,0.00034543645,0.0011887,0.000014575343,0.00013827998,0.00016615327,0.27030182,0.000008001119,0.7264835,0.0002853267],"study_design_scores_gemma":[0.0010705909,0.0010241577,0.0023627032,0.00014728543,0.00094630755,0.000008181923,0.00015868321,0.003347516,0.22814694,0.000021524762,0.76170266,0.0010634317],"about_ca_topic_score_codex":0.00016966234,"about_ca_topic_score_gemma":0.00086699566,"teacher_disagreement_score":0.6820451,"about_ca_system_score_codex":0.0001269542,"about_ca_system_score_gemma":0.00019774445,"threshold_uncertainty_score":0.99953},"labels":[],"label_agreement":null},{"id":"W2066457589","doi":"10.1186/s12977-015-0150-z","title":"The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA","year":2015,"lang":"en","type":"article","venue":"Retrovirology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Program for Changjiang Scholars and Innovative Research Team in University; Peking Union Medical College; Canadian Institutes of Health Research; Chinese Academy of Medical Sciences","keywords":"CRISPR; Cas9; Genome editing; DNA; Virology; Biology; Gene; Jurkat cells; Computational biology; Genetics; T cell; Immune system","score_opus":0.009639150517552578,"score_gpt":0.2666982627753903,"score_spread":0.25705911225783773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066457589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885753,0.0019504341,0.005778387,0.00063697353,0.0006574515,0.00021289999,0.000009017531,0.000052889507,0.0021266735],"genre_scores_gemma":[0.9982091,0.0000563663,0.00017678889,0.00008944076,0.0003939004,0.000032760418,0.000031338237,0.000025660383,0.0009846089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989899,0.00007580047,0.00018735837,0.00027727277,0.00011312553,0.00035657818],"domain_scores_gemma":[0.9993471,0.00001960188,0.00005551787,0.0004031617,0.000055304383,0.00011934942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002583736,0.00015407264,0.00014423855,0.000027578775,0.00009691767,0.000026080366,0.0002351584,0.00017609536,0.000002101988],"category_scores_gemma":[0.000105036655,0.000112158166,0.00006915417,0.00005988406,0.000091080416,0.0000024670494,0.0001406074,0.00012510386,0.00005255956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005622227,0.000076232696,0.027020724,0.000079006786,0.00022044366,0.00004319448,0.00019849003,0.0024601973,0.93139386,0.002652259,0.031003319,0.0042900285],"study_design_scores_gemma":[0.00198536,0.002008654,0.011124066,0.000018002931,0.00007265658,0.00037259553,0.0009171052,0.0028275172,0.52859825,0.00009223663,0.45135185,0.0006317073],"about_ca_topic_score_codex":0.000017446004,"about_ca_topic_score_gemma":0.0000143388515,"teacher_disagreement_score":0.42034853,"about_ca_system_score_codex":0.00004081929,"about_ca_system_score_gemma":0.000059422302,"threshold_uncertainty_score":0.45736775},"labels":[],"label_agreement":null},{"id":"W2066533093","doi":"10.1186/1745-6150-3-48","title":"Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'–5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch","year":2008,"lang":"en","type":"article","venue":"Biology Direct","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; State University of New York Upstate Medical University; University of Ottawa; Université Laval; State University of New York","keywords":"Biology; Germline; Piwi-interacting RNA; Lineage (genetic); Genetics; Homologous chromosome; Homologous recombination; Retrotransposon; Exonuclease; Evolutionary biology; Genome; Transposable element; Gene; Polymerase","score_opus":0.012426881477549341,"score_gpt":0.24842716517115243,"score_spread":0.2360002836936031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066533093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891778,0.005435271,0.0031974157,0.0011028537,0.0002298113,0.00036547825,0.00006646652,0.000021876023,0.00040297591],"genre_scores_gemma":[0.9965564,0.0010988922,0.00061032217,0.0007281106,0.00044775446,0.00011814298,0.00019494527,0.000020488294,0.00022492165],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99867404,0.0002263951,0.00023358413,0.00047333175,0.00009620073,0.00029645915],"domain_scores_gemma":[0.99933255,0.00009582611,0.00005045671,0.00036737285,0.00007776214,0.00007604702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002866123,0.00022356925,0.00019709032,0.00008141852,0.0002477399,0.000011667805,0.00021775212,0.00022431627,0.000020293075],"category_scores_gemma":[0.000091699956,0.00014642392,0.00007635521,0.00021386585,0.00016756119,0.000005171106,0.00015959053,0.00021468612,0.000018253324],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045037456,0.00015379592,0.00580547,0.000010665445,0.00007700324,0.00007978335,0.0020355862,0.0006919901,0.97993785,0.00028608236,0.0061657513,0.0043056225],"study_design_scores_gemma":[0.0011954571,0.00071609905,0.31917527,0.000023230486,0.00001754081,0.0006363582,0.00040580236,0.00013006457,0.12016136,0.000096294665,0.55690336,0.0005391507],"about_ca_topic_score_codex":0.00006452842,"about_ca_topic_score_gemma":0.00022551452,"teacher_disagreement_score":0.8597765,"about_ca_system_score_codex":0.00002918719,"about_ca_system_score_gemma":0.00008424682,"threshold_uncertainty_score":0.5970994},"labels":[],"label_agreement":null},{"id":"W2067472732","doi":"10.1002/1526-968x(200007)27:3<95::aid-gene10>3.0.co;2-a","title":"FACS for the isolation of individual cells from transgenic mice harboring a fluorescent protein reporter","year":2000,"lang":"en","type":"article","venue":"genesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Green fluorescent protein; Biology; Reporter gene; Transgenesis; Cell sorting; Transgene; Flow cytometry; Yellow fluorescent protein; Fluorescent protein; Fluorescence; Molecular biology; Cell biology; Gene; Genetics; Gene expression; Embryogenesis","score_opus":0.009714540443763879,"score_gpt":0.25500024274330607,"score_spread":0.2452857022995422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067472732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95307064,0.0013154816,0.045017526,0.00004470278,0.00008299223,0.00036802026,0.00007004743,0.0000065540657,0.000024052584],"genre_scores_gemma":[0.9944347,0.00012386848,0.0048488476,0.00002972281,0.00021954993,0.00007308021,0.000056152738,0.000016588307,0.00019745865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999402,0.000011814136,0.00018594769,0.00018320057,0.000088836096,0.00012823124],"domain_scores_gemma":[0.99967545,0.000010854126,0.000038367976,0.00022348748,0.00002651489,0.000025336964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001024007,0.00008848861,0.00008195564,0.000012911886,0.000041780906,0.000011164967,0.00012822113,0.0000699911,0.00005128507],"category_scores_gemma":[0.0000067214837,0.00007267494,0.00009246381,0.00003792051,0.000015678039,0.0000015616092,0.00001386512,0.000022909628,0.0000016828668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048471433,0.000015369958,0.00012843117,0.000015104873,0.00006628691,1.2707898e-7,0.00014367182,0.0015232365,0.97926986,6.7643185e-7,0.00018988931,0.018598879],"study_design_scores_gemma":[0.00025576833,0.00005898772,0.005767135,0.000008377704,0.000061732004,6.856516e-7,0.00003908983,0.00045836312,0.98293525,0.000005849143,0.010316942,0.00009183091],"about_ca_topic_score_codex":0.00004544684,"about_ca_topic_score_gemma":0.000021597021,"teacher_disagreement_score":0.041364107,"about_ca_system_score_codex":0.0000035073592,"about_ca_system_score_gemma":0.000019807947,"threshold_uncertainty_score":0.2963598},"labels":[],"label_agreement":null},{"id":"W2067970085","doi":"10.1007/s10806-011-9356-9","title":"Legal and Ethical Apprehensions Regarding Relational Object. The Case of Genetically Modified Fish","year":2011,"lang":"en","type":"article","venue":"Journal of Agricultural and Environmental Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Epistemology; Pluralism (philosophy); Object (grammar); Opposition (politics); Set (abstract data type); Sociology; Human animal; Environmental ethics; Computer science; Political science; Ecology; Law; Philosophy; Artificial intelligence; Biology","score_opus":0.02091586096435828,"score_gpt":0.25471389737548883,"score_spread":0.23379803641113056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067970085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972891,0.00064225955,0.0011170552,0.00064530433,0.000055311688,0.000041524505,0.000007813902,9.962937e-7,0.00020063011],"genre_scores_gemma":[0.99701744,0.0009504435,0.0017123494,0.0001769149,0.00009137216,6.9315286e-7,0.000006917958,0.000004066915,0.00003978842],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994477,0.000052063835,0.00021500661,0.000090327914,0.000112022615,0.000082902494],"domain_scores_gemma":[0.99970335,0.000055894558,0.00008692969,0.00005982775,0.000022824344,0.00007115099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024522655,0.000083139756,0.00009839954,0.000011404825,0.00010145641,0.000008312004,0.000050730676,0.00022468358,0.0000052122564],"category_scores_gemma":[0.000063118416,0.00004565227,0.000060920745,0.000019409641,0.00018498297,0.00000459582,0.00008171685,0.0005286058,1.4620583e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013636447,0.00007651134,0.0014941011,0.00004794684,0.00019332259,0.000086469474,0.0025495903,0.0022627586,0.98721725,0.0035980868,0.0004640862,0.0018735013],"study_design_scores_gemma":[0.0022395859,0.0018212618,0.7561616,0.00013022312,0.00042274295,0.039944574,0.010748951,0.0005145784,0.18308544,0.0010156436,0.0032568318,0.0006586124],"about_ca_topic_score_codex":0.000010453775,"about_ca_topic_score_gemma":0.000015893249,"teacher_disagreement_score":0.8041318,"about_ca_system_score_codex":0.0000049206315,"about_ca_system_score_gemma":0.000011598498,"threshold_uncertainty_score":0.22965585},"labels":[],"label_agreement":null},{"id":"W2068087620","doi":"10.1093/nar/gkh926","title":"Cis-acting regulatory sequences promote high-frequency gene conversion between repeated sequences in mammalian cells","year":2004,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Biology; Locus (genetics); Enhancer; Gene; Scaffold/matrix attachment region; Gene conversion; Genetics; Molecular biology; DNA; Chromatin; Genome; Gene expression; Chromatin remodeling","score_opus":0.02771250829069531,"score_gpt":0.33515636058875575,"score_spread":0.3074438522980604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068087620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973744,0.0005112927,0.0007325698,0.00030335333,0.00016404696,0.0003492007,0.000022540597,0.0000346922,0.00050787226],"genre_scores_gemma":[0.9940754,0.00019977705,0.0050051627,0.000023657989,0.00028474172,0.000021917574,0.00009462969,0.0000412407,0.00025346383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975792,0.0001550513,0.0003569666,0.00064983015,0.00054295757,0.000715978],"domain_scores_gemma":[0.99900347,0.000025382016,0.00005959798,0.00055133994,0.00017250613,0.0001877216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010407222,0.00021109832,0.0002250623,0.0002223113,0.00018801799,0.00006134557,0.00049091905,0.00030611994,0.00005767843],"category_scores_gemma":[0.00012224799,0.00021097923,0.00007189738,0.0004800512,0.0002632877,0.000016491314,0.00022021786,0.00043733322,0.00004290109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028248152,0.000025587422,0.006348968,0.000055636432,0.00002259692,0.00005883819,0.00018839371,0.00062035455,0.9900974,0.000032803688,0.00007183346,0.0024493341],"study_design_scores_gemma":[0.00064602995,0.0003762226,0.009226711,0.00007228095,0.0000063750963,0.000012625015,0.00037208156,0.000022684204,0.98720807,0.0004192798,0.0013783601,0.00025928603],"about_ca_topic_score_codex":0.0012126504,"about_ca_topic_score_gemma":0.000113237955,"teacher_disagreement_score":0.0042725927,"about_ca_system_score_codex":0.00016063267,"about_ca_system_score_gemma":0.0002449324,"threshold_uncertainty_score":0.8603483},"labels":[],"label_agreement":null},{"id":"W2070365533","doi":"10.1080/07391102.2013.786344","title":"102 Genome engineering nucleases derived from GIY-YIG homing endonucleases","year":2013,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Transcription activator-like effector nuclease; Nuclease; Homing endonuclease; Genome editing; Zinc finger nuclease; Cleave; DNA; Endonuclease; Computational biology; Biology; Genome; Genetics; Gene","score_opus":0.00211057968208328,"score_gpt":0.2081904031433056,"score_spread":0.20607982346122233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070365533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9228593,0.003949676,0.072792314,0.000062275794,0.00018470324,0.00008065879,0.00004430947,0.00000758569,0.000019140818],"genre_scores_gemma":[0.9882359,0.00032321244,0.010921807,0.000121031204,0.00029728358,0.0000010743238,0.000052601517,0.000036148933,0.000010964605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999148,0.000017507547,0.00029568217,0.00018894307,0.00013832429,0.00021155419],"domain_scores_gemma":[0.9993877,0.000013952765,0.00013578498,0.00018972106,0.00010682328,0.00016604215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000039444352,0.00020264012,0.00022472053,0.000090165966,0.00005115907,0.00007879097,0.00016809309,0.00013905,0.00003906918],"category_scores_gemma":[0.000062151936,0.000182298,0.00012558053,0.000069886875,0.000038330276,0.000012606341,0.00008731913,0.00013232346,0.000001320873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019009336,0.000010975324,0.0006181569,0.000018156428,0.00014049758,0.000026801297,0.00004856778,0.0014186605,0.993622,0.000019168514,0.000029567173,0.0040284554],"study_design_scores_gemma":[0.0024237246,0.00087087357,0.09846694,0.00013316542,0.00033083698,0.0011756222,0.00056779396,0.027057748,0.86251163,0.0005361124,0.0047812806,0.001144291],"about_ca_topic_score_codex":0.00003771911,"about_ca_topic_score_gemma":0.000010743213,"teacher_disagreement_score":0.13111037,"about_ca_system_score_codex":0.000019310384,"about_ca_system_score_gemma":0.000029516199,"threshold_uncertainty_score":0.74338967},"labels":[],"label_agreement":null},{"id":"W2071685904","doi":"10.1002/yea.1469","title":"Disintegrator vectors for single‐copy yeast chromosomal integration","year":2007,"lang":"en","type":"article","venue":"Yeast","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Plasmid; Gene; Genetics; Computational biology; Reporter gene; Expression cassette; Vector (molecular biology); Gene expression; Recombinant DNA","score_opus":0.009298490131151915,"score_gpt":0.29261795225218423,"score_spread":0.2833194621210323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071685904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7380073,0.00026148747,0.25908273,0.00003846672,0.0004807657,0.00018931304,0.000046421712,0.00002622852,0.0018673099],"genre_scores_gemma":[0.9960753,0.0000054887123,0.0024978528,0.00004434672,0.00083327055,0.000012261219,0.0001513201,0.00002506551,0.00035510462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937314,0.0000053697518,0.0001356576,0.00020280013,0.00007015967,0.00021285973],"domain_scores_gemma":[0.999669,0.0000054861307,0.00002822886,0.00016828695,0.00005528402,0.000073728064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105176696,0.00011712739,0.000081856815,0.000031979194,0.00004135153,0.00002048703,0.000087908855,0.000093554874,0.000015710826],"category_scores_gemma":[0.000062223175,0.00010878247,0.00007928632,0.00005859144,0.000027101054,0.0000024322596,0.000022488503,0.00004636717,0.000010000566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049583672,0.000026748006,0.00032700837,0.000008756106,0.000013782411,0.000001083782,0.000039186485,0.000025492485,0.98999727,0.000088143104,0.0006299012,0.008793019],"study_design_scores_gemma":[0.00027830066,0.00021162372,0.0021187388,0.000013987968,0.000011113063,0.000013577845,0.00014713581,0.00007781662,0.96279657,0.000011511202,0.03417701,0.00014263685],"about_ca_topic_score_codex":0.000005806721,"about_ca_topic_score_gemma":0.00012905353,"teacher_disagreement_score":0.258068,"about_ca_system_score_codex":0.000017838636,"about_ca_system_score_gemma":0.00001892503,"threshold_uncertainty_score":0.44360206},"labels":[],"label_agreement":null},{"id":"W2071857414","doi":"10.1007/s12032-014-0255-6","title":"Wild-type genotypes of BRCA1 gene SNPs combined with micro-RNA over-expression in mammary tissue leading to familial breast cancer with an increased risk of distant metastases’ occurrence","year":2014,"lang":"en","type":"article","venue":"Medical Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"Breast cancer; Single-nucleotide polymorphism; Oncology; Cancer; Internal medicine; Genotyping; Medicine; Genotype; Biology; Metastasis; Cancer research; Gene; Pathology; Genetics","score_opus":0.005094313034997797,"score_gpt":0.29659931643774984,"score_spread":0.29150500340275204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071857414","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805107,0.0003543348,0.01857703,0.000078432284,0.000108493194,0.00017793506,0.00012167737,0.00000698073,0.00006441227],"genre_scores_gemma":[0.9940151,0.00019257139,0.005430632,0.000121389356,0.000087339846,0.000017760942,0.00011311794,0.00001438119,0.000007721065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987185,0.00017206717,0.0002954393,0.00033716141,0.00023218222,0.00024463626],"domain_scores_gemma":[0.9992056,0.000053224565,0.00012420026,0.00030157817,0.00008957953,0.00022584286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036697637,0.00016463804,0.0004023374,0.0000689284,0.000024183,0.0000033820334,0.00025199234,0.00017314935,0.00004176547],"category_scores_gemma":[0.0001237988,0.000121873294,0.00002653647,0.00016825873,0.00014064062,0.0000049014807,0.000105810155,0.00015230013,6.964103e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021148368,0.00023667463,0.019033857,0.000058256803,0.000058312202,0.00001991522,0.000111946894,0.0010521851,0.96204096,0.00001599239,0.0001394708,0.01511762],"study_design_scores_gemma":[0.003003001,0.005836122,0.056104217,0.00014977397,0.00008520059,0.00004130762,0.000050840757,0.00051335717,0.92878985,0.000010476643,0.005147161,0.00026869157],"about_ca_topic_score_codex":0.0007214916,"about_ca_topic_score_gemma":0.0015078608,"teacher_disagreement_score":0.03707036,"about_ca_system_score_codex":0.000029229865,"about_ca_system_score_gemma":0.00028463907,"threshold_uncertainty_score":0.49698487},"labels":[],"label_agreement":null},{"id":"W2074570440","doi":"10.1371/journal.pbio.0060239","title":"A Specificity Map for the PDZ Domain Family","year":2008,"lang":"en","type":"article","venue":"PLoS Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":491,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Genentech","keywords":"PDZ domain; Biology; Caenorhabditis elegans; Protein domain; Mutant; Plasma protein binding; Human proteome project; Protein–protein interaction; Binding selectivity; Computational biology; Proteome; Cell biology; Genetics; Gene; Proteomics; Biochemistry","score_opus":0.02136129055972648,"score_gpt":0.2970654815593814,"score_spread":0.27570419099965493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074570440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8891508,0.003969649,0.10458406,0.00061892957,0.0003798994,0.00035693016,0.000050790168,0.000022859598,0.0008660913],"genre_scores_gemma":[0.9949446,0.00041921015,0.0029513096,0.0003778181,0.00062712317,0.000076388904,0.000069385365,0.000016547392,0.00051763805],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999372,0.00002084229,0.00011838588,0.00023011725,0.00003288394,0.00022577109],"domain_scores_gemma":[0.999586,0.000040752606,0.000024458015,0.0002766904,0.000035953653,0.000036168214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007950224,0.000105837775,0.00010546669,0.000016307578,0.00011654619,0.0000038718354,0.00018563465,0.000119439625,0.0000141131395],"category_scores_gemma":[0.000038650593,0.00007472805,0.000081679624,0.000031932537,0.00010964154,5.858882e-7,0.00006197625,0.000057012403,0.00001681761],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005155833,0.000034197303,0.0013172792,0.000008908631,0.00006664391,0.0000012389021,0.000047628564,0.000051113366,0.9902,0.00039896142,0.007170345,0.00065211946],"study_design_scores_gemma":[0.0005999666,0.0003726896,0.005942058,0.0000035695723,0.000019764713,0.000029766055,0.0000993604,0.00023638167,0.29219434,0.0004928995,0.699783,0.00022620018],"about_ca_topic_score_codex":0.000007235361,"about_ca_topic_score_gemma":0.000009939776,"teacher_disagreement_score":0.6980057,"about_ca_system_score_codex":0.000005142753,"about_ca_system_score_gemma":0.000022163134,"threshold_uncertainty_score":0.30473214},"labels":[],"label_agreement":null},{"id":"W2074933455","doi":"10.1038/nature14121","title":"Biocontainment of genetically modified organisms by synthetic protein design","year":2015,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":462,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; U.S. Department of Defense; Life Sciences Research Foundation; National Defense Science and Engineering Graduate; U.S. Department of Energy; Howard Hughes Medical Institute","keywords":"Mutagenesis; Organism; Genetically modified organism; Synthetic biology; Biology; Horizontal gene transfer; Biotechnology; Escherichia coli; Computational biology; Model organism; Genetic code; Gene; Biochemical engineering; Genetics; Mutation; Genome","score_opus":0.007994336066708648,"score_gpt":0.266636796238196,"score_spread":0.2586424601714874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074933455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67326903,0.008750925,0.3157338,0.00035393695,0.00016965478,0.0006647298,0.000028992737,0.000024601411,0.0010043448],"genre_scores_gemma":[0.9914272,0.000022965529,0.00790524,0.000114759365,0.000059757684,0.000021010517,0.000025414514,0.00002092976,0.0004027307],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993001,0.00003188701,0.00013358275,0.00021220831,0.00016116242,0.00016103844],"domain_scores_gemma":[0.99951726,0.0000046825853,0.000033304943,0.00026056575,0.00008030582,0.00010385694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015374612,0.00011798863,0.00010952643,0.000019906895,0.000013883311,0.0000078321655,0.00016154214,0.00060749264,0.00000894051],"category_scores_gemma":[0.00009763434,0.00010605423,0.000038633236,0.000056649114,0.000033672397,9.3196036e-7,0.00005507826,0.00024811845,0.0000037394104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053328615,0.000039726627,0.000016595905,0.000012007147,0.000023078428,0.0000012317353,0.000026121314,0.00089619803,0.99391484,0.00010624903,0.0040082145,0.0009023924],"study_design_scores_gemma":[0.0004037861,0.00031383897,0.00004406809,0.000010169032,0.000011527707,0.0000054755865,0.000029009661,0.00027478952,0.99082893,0.00013707626,0.0078112762,0.00013006444],"about_ca_topic_score_codex":0.0000029947328,"about_ca_topic_score_gemma":8.3160535e-7,"teacher_disagreement_score":0.31815815,"about_ca_system_score_codex":0.000011816519,"about_ca_system_score_gemma":0.00005879469,"threshold_uncertainty_score":0.46855396},"labels":[],"label_agreement":null},{"id":"W2075549508","doi":"10.1073/pnas.041449398","title":"Production of zebrafish germ-line chimeras from embryo cell cultures","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Biology; Zebrafish; Embryonic stem cell; Germ cell; Cell biology; Embryo; Chimera (genetics); Stem cell; Cell culture; Gene targeting; Cellular differentiation; Genetics; Molecular biology; Gene","score_opus":0.016201001945850148,"score_gpt":0.3099402357895429,"score_spread":0.2937392338436927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075549508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969228,0.0005123019,0.000006944194,0.0006486914,0.000035671772,0.00007706283,0.000008170076,0.0000028933414,0.0017854619],"genre_scores_gemma":[0.99812543,0.00014527533,0.0011272408,0.00005872642,0.00020012549,0.0000026371645,8.4918327e-7,0.0000029251507,0.00033675917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992085,0.0000022595996,0.00018495513,0.0001756933,0.0003502581,0.00007834744],"domain_scores_gemma":[0.999632,0.0000073578176,0.00017820488,0.000009216516,0.00015636306,0.000016851825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002670627,0.000062254905,0.00008210803,0.00004006426,0.000051286366,0.0000053946624,0.00031192592,0.00006390213,0.000006722159],"category_scores_gemma":[0.00016692675,0.000043634416,0.000052420844,0.0002147589,0.0002162106,0.000011200869,0.000069057,0.000055642544,2.4886134e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001084882,0.00002790697,0.0022989376,0.000018521145,0.000008769762,1.0179346e-9,0.000051198935,0.0006928749,0.9956654,0.00016980492,0.000927626,0.000128124],"study_design_scores_gemma":[0.000083430954,0.00003815508,0.04288345,0.000019756917,0.000007990702,0.0000025370214,0.000070702576,0.00013157366,0.954682,0.0012892372,0.0007428035,0.00004835195],"about_ca_topic_score_codex":0.000006911464,"about_ca_topic_score_gemma":1.4424155e-7,"teacher_disagreement_score":0.040983375,"about_ca_system_score_codex":0.0000035711619,"about_ca_system_score_gemma":0.000013163477,"threshold_uncertainty_score":0.17793599},"labels":[],"label_agreement":null},{"id":"W2076607155","doi":"10.1002/jcp.22787","title":"Integrating post‐transcriptional regulation into the embryonic stem cell gene regulatory network","year":2011,"lang":"en","type":"review","venue":"Journal of Cellular Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Embryonic stem cell; Epigenetics; Gene regulatory network; Regulation of gene expression; Gene; Stem cell; Computational biology; Gene expression; Transcriptional regulation; Cell fate determination; Transcription factor; Cell biology; Genetics","score_opus":0.01301800519981695,"score_gpt":0.2674419047996265,"score_spread":0.25442389959980954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076607155","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00444227,0.98376024,0.010393337,0.000013367201,0.001072882,0.00021513466,0.000004275201,0.000005519558,0.000092958646],"genre_scores_gemma":[0.012712527,0.98219466,0.0012985404,0.00005227467,0.0030300382,0.000012092684,0.00016117454,0.00007588187,0.0004627987],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979976,0.00035202512,0.0008612641,0.00030880191,0.00016219336,0.0003181457],"domain_scores_gemma":[0.99823195,0.00004597289,0.0008881774,0.00050289556,0.00023847459,0.000092516515],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005832424,0.0003945395,0.00089190924,0.00009088113,0.000121300436,0.000018638531,0.00057052344,0.0004931279,0.000036087327],"category_scores_gemma":[0.000014549803,0.0002629436,0.00087562704,0.00012901222,0.00010690813,0.0000062250133,0.00010889399,0.0005707093,0.00001070013],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061050894,0.00005348922,9.863866e-7,0.0014118123,0.00041671866,0.000007037108,0.00016228564,0.0009739303,0.7588823,0.00032972448,0.0011911471,0.23650955],"study_design_scores_gemma":[0.00024829616,0.00046200756,0.00007122077,0.0009510209,0.0005831205,0.00014824311,0.000058578407,0.000033291988,0.018210044,0.00022801709,0.97861886,0.00038727702],"about_ca_topic_score_codex":0.0000031730165,"about_ca_topic_score_gemma":0.000004178532,"teacher_disagreement_score":0.9774277,"about_ca_system_score_codex":0.00004320504,"about_ca_system_score_gemma":0.0003018684,"threshold_uncertainty_score":0.9999823},"labels":[],"label_agreement":null},{"id":"W2077993289","doi":"10.1016/j.febslet.2007.03.072","title":"Regulation of the BRCA1 promoter in ovarian surface epithelial cells and ovarian carcinoma cells","year":2007,"lang":"en","type":"article","venue":"FEBS Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of British Columbia","funders":"","keywords":"CREB; AP-1 transcription factor; Transcription factor; Ovarian carcinoma; Cancer research; Response element; Promoter; Transcription (linguistics); Cell culture; Biology; Cell biology; Chemistry; Ovarian cancer; Gene; Gene expression; Genetics; Cancer","score_opus":0.004568275733838775,"score_gpt":0.22168919227923972,"score_spread":0.21712091654540094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077993289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904039,0.000057836176,0.008574441,0.0004808063,0.0002156484,0.00015374637,0.000008680116,0.000002816728,0.00010214667],"genre_scores_gemma":[0.99835616,0.0000046601476,0.0011380411,0.000271983,0.00010516589,9.772789e-7,0.000006259313,0.00001239576,0.00010435114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940187,0.000024855568,0.00015593268,0.00017495692,0.00007625109,0.00016610669],"domain_scores_gemma":[0.9996873,0.000008322084,0.000040964518,0.00022009404,0.000012962177,0.000030321475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020643727,0.00008998838,0.000079869096,0.000024468829,0.000023129765,0.000008010846,0.00009181218,0.00007687763,0.0000041547773],"category_scores_gemma":[0.0000063126663,0.0000761852,0.000037552567,0.00006883746,0.000043150572,0.0000021173598,0.000053141932,0.00006378854,9.77662e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023587121,0.000020481133,0.004194168,0.000017678787,0.000006501187,0.0000016552998,0.00015776545,0.0008953077,0.9942091,0.000008771556,0.00020203882,0.0002629304],"study_design_scores_gemma":[0.0005616728,0.000022459491,0.16630548,0.000007691196,0.000005535084,0.0000035047183,0.000016338407,0.00011188677,0.83164525,0.000006579301,0.0012358786,0.00007770004],"about_ca_topic_score_codex":0.000080671285,"about_ca_topic_score_gemma":0.00006809959,"teacher_disagreement_score":0.16256385,"about_ca_system_score_codex":0.000008988358,"about_ca_system_score_gemma":0.000010617238,"threshold_uncertainty_score":0.31067422},"labels":[],"label_agreement":null},{"id":"W2078004986","doi":"10.1186/1472-6750-11-28","title":"Genome-wide target profiling of piggyBac and Tol2in HEK 293: pros and cons for gene discovery and gene therapy","year":2011,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Institute of Genetics; National Institutes of Health; Chang Gung Medical Foundation; Massey University; National Science Council; Children's Medical Research","keywords":"Transposase; Biology; Transposable element; Insertional mutagenesis; Computational biology; Genome; Genetics; Gene targeting; Gene; Human genome","score_opus":0.015577680604823963,"score_gpt":0.2547670969918497,"score_spread":0.23918941638702573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078004986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85221416,0.010696187,0.13647848,0.0000655068,0.000038609425,0.0004196442,0.00005126165,0.000018031924,0.000018135639],"genre_scores_gemma":[0.88688886,0.0030757557,0.10979213,0.000040163457,0.00003498926,0.000055964625,0.000036371726,0.000022618526,0.000053135256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992266,0.000011952773,0.00017566422,0.0003438297,0.00003201338,0.00020989754],"domain_scores_gemma":[0.99963146,0.000015947106,0.00005789193,0.00022507705,0.000028320239,0.000041275573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010377608,0.00014917525,0.00019570427,0.00006557021,0.000045131634,0.000009131694,0.0000849567,0.00030522855,0.0000017044282],"category_scores_gemma":[0.00005116366,0.00013669502,0.000031899926,0.00004516201,0.0002502006,0.0000041929598,0.00012136237,0.00006756002,1.2910876e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010144603,0.000024730516,0.019425165,0.000067680776,0.000043345157,7.837783e-7,0.000051938146,0.000005906445,0.97898716,0.00024345652,0.000006448021,0.0010419198],"study_design_scores_gemma":[0.0007421267,0.00050898443,0.011458656,0.000005216555,0.000014330772,0.00003507429,0.000082219645,0.0000960701,0.9853034,0.00037703084,0.0012135318,0.00016333547],"about_ca_topic_score_codex":0.000009021978,"about_ca_topic_score_gemma":0.000012525597,"teacher_disagreement_score":0.034674738,"about_ca_system_score_codex":0.000002769302,"about_ca_system_score_gemma":0.00003049045,"threshold_uncertainty_score":0.5574261},"labels":[],"label_agreement":null},{"id":"W2078216990","doi":"10.1038/nmeth.2445","title":"Gene-pair expression signatures reveal lineage control","year":2013,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences","keywords":"Multicellular organism; Biology; Cell fate determination; Gene regulatory network; Gene; Transcription factor; Regulation of gene expression; Gene expression; Computational biology; Cell type; Lineage (genetic); Cellular differentiation; Genetics; Cell; Transcriptional regulation; Cell biology","score_opus":0.005356270228338222,"score_gpt":0.3569703993652538,"score_spread":0.3516141291369156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078216990","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2833823,0.022716088,0.69031465,0.00029575918,0.0011026185,0.0005533721,0.00002333213,0.000080755606,0.0015310933],"genre_scores_gemma":[0.70645875,0.000040825016,0.29053414,0.0007460972,0.00068622833,0.000041779113,0.000034743935,0.00002785741,0.0014295918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891853,0.00018222001,0.00017361749,0.00034484098,0.000119331846,0.00026145484],"domain_scores_gemma":[0.9992829,0.000056101853,0.000047300276,0.0004041023,0.00009939554,0.00011020198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038283563,0.00018832434,0.00017605891,0.000043038166,0.000057202138,0.000027954567,0.00021497183,0.0006592314,0.000080348174],"category_scores_gemma":[0.0002837592,0.00015440129,0.00012209821,0.0000760784,0.000027990727,0.0000035440978,0.00007243729,0.0004516535,0.0000105464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018041179,0.000015433827,0.0002852668,0.000015025084,0.000024141786,0.0000014608603,0.000013043798,0.00039606876,0.97356284,0.000008189235,0.014626403,0.011034106],"study_design_scores_gemma":[0.0004149325,0.00007204746,0.0039307666,0.000009397662,0.000012354106,0.000007558695,0.000010346715,0.0004156101,0.9168525,0.00005303908,0.078032345,0.00018911631],"about_ca_topic_score_codex":0.00000533958,"about_ca_topic_score_gemma":0.0000010285992,"teacher_disagreement_score":0.42307645,"about_ca_system_score_codex":0.000007826385,"about_ca_system_score_gemma":0.000019847099,"threshold_uncertainty_score":0.6296302},"labels":[],"label_agreement":null},{"id":"W2078283036","doi":"10.4161/epi.6.12.18206","title":"Dramatic replacement of histone variants during genome remodeling in nuclear-transferred embryos","year":2011,"lang":"en","type":"article","venue":"Epigenetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Windsor","keywords":"Biology; Histone; Chromatin; Totipotent; Histone H3; Chromatin remodeling; Cell biology; Genetics; Embryo; Histone methylation; Somatic cell; Histone H2A; Zygote; Genome; Pronucleus; DNA; Embryonic stem cell; Embryogenesis; DNA methylation; Gene; Gene expression","score_opus":0.014369917129867616,"score_gpt":0.2858795564415654,"score_spread":0.27150963931169775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078283036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856371,0.0011305955,0.011611429,0.000012120532,0.00012225653,0.00019042668,0.0000072143075,0.0000118624175,0.001276967],"genre_scores_gemma":[0.9911757,0.00046479126,0.008010852,0.000021573274,0.000049465823,0.000007095414,0.000014042653,0.00003940967,0.00021704634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988923,0.000028154374,0.0004116452,0.00028412417,0.00011881076,0.0002649292],"domain_scores_gemma":[0.9993951,0.000003801264,0.000056813875,0.00043417246,0.000040499548,0.00006966452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566604,0.0001526159,0.00018725768,0.00008039165,0.000032276344,0.0000053110666,0.00019359223,0.00011573978,0.00006936443],"category_scores_gemma":[0.000029635677,0.00017437057,0.00006614931,0.00009548745,0.0000372332,0.000002192994,0.000076532364,0.00008225592,0.000005754531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009644217,0.00008805878,0.0009285758,0.000093700226,0.000029575713,0.000004742225,0.0011083261,0.0047758347,0.99256116,0.000023456343,0.000008403777,0.00028174062],"study_design_scores_gemma":[0.0017697809,0.00043804172,0.109964706,0.00009772328,0.00005200601,0.000025600022,0.00041757396,0.0038585626,0.8815696,0.00014255548,0.0010896538,0.0005741773],"about_ca_topic_score_codex":0.000033989745,"about_ca_topic_score_gemma":0.00003742993,"teacher_disagreement_score":0.11099152,"about_ca_system_score_codex":0.000022964183,"about_ca_system_score_gemma":0.00002855115,"threshold_uncertainty_score":0.7110625},"labels":[],"label_agreement":null},{"id":"W2080009731","doi":"10.1158/1538-7445.am2012-3116","title":"Abstract 3116: Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in ovarian cancer","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Loss of heterozygosity; Ovarian cancer; Biology; Homologous recombination; Cancer research; DNA repair; Breast cancer; Gene; Genetics; Cancer; Allele","score_opus":0.028556479772308487,"score_gpt":0.3759917350272013,"score_spread":0.3474352552548928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080009731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956091,0.0035789667,0.00019001275,0.000025970641,0.00017683479,0.00021362744,0.000059558923,0.0000051710294,0.00014077364],"genre_scores_gemma":[0.9983243,0.0012766903,0.000045708814,0.0000071075992,0.00014531655,0.00007827339,0.000021691347,0.000016587366,0.00008433264],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901634,0.0000669263,0.00020887326,0.00019400258,0.00017350292,0.00034033105],"domain_scores_gemma":[0.9994734,0.000022181637,0.000050329112,0.00026522757,0.00011655359,0.0000723367],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000601482,0.00008368175,0.0001393412,0.0001079185,0.000024417452,0.000003564249,0.00015293564,0.00011934675,0.00008908775],"category_scores_gemma":[0.00004667574,0.0000862103,0.00006438233,0.00010361938,0.000059251062,0.0000051210695,0.00010556491,0.00016325532,0.000001409689],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054954966,0.00006833123,0.34821302,0.00017486651,0.000027343594,0.0000014988839,0.00012500497,0.0005324829,0.64967036,0.000008687872,0.00014689827,0.00097653037],"study_design_scores_gemma":[0.0002813617,0.00007005988,0.53460175,0.000043873428,0.000003890619,0.0000015745044,0.000024244306,0.000012959453,0.46462744,0.000008628938,0.00026892,0.000055309592],"about_ca_topic_score_codex":0.0017611029,"about_ca_topic_score_gemma":0.0007642298,"teacher_disagreement_score":0.18638872,"about_ca_system_score_codex":0.000080204125,"about_ca_system_score_gemma":0.000103448496,"threshold_uncertainty_score":0.35155538},"labels":[],"label_agreement":null},{"id":"W2080796860","doi":"10.1371/journal.pgen.1000007","title":"Genome-Wide Assessments Reveal Extremely High Levels of Polymorphism of Two Active Families of Mouse Endogenous Retroviral Elements","year":2008,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Terry Fox Research Institute","funders":"BC Cancer Agency; Canadian Institutes of Health Research","keywords":"Biology; Genetics; Gene; Genome; Intron; Endogenous retrovirus; Retrotransposon; genomic DNA; Transposable element","score_opus":0.03920954690958602,"score_gpt":0.2929871060684118,"score_spread":0.25377755915882577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080796860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956491,0.0012158251,0.002002628,0.0000048362294,0.000074556745,0.0002563224,0.0004044261,0.0000074117816,0.00038486556],"genre_scores_gemma":[0.99136615,0.00070250814,0.0073989094,0.000020130441,0.000076783894,0.000010402742,0.00008933968,0.000042922886,0.00029286984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840826,0.000049164275,0.00059680094,0.0003036072,0.0003431295,0.00029901715],"domain_scores_gemma":[0.9988763,0.000021371701,0.00030019932,0.000511332,0.0002111861,0.00007963261],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008024171,0.00022762429,0.0003816079,0.00010358886,0.00004019938,0.0000026288383,0.00030229203,0.000121369834,0.000025009876],"category_scores_gemma":[0.00004586534,0.00024575106,0.00012818423,0.00012229315,0.00015506655,0.000003874124,0.00017609779,0.00008751229,0.0000012879342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007668459,0.00021557331,0.024941124,0.000084664716,0.00026606498,0.0000041720687,0.0001868138,0.001084716,0.97257495,0.000005503649,0.000018138155,0.00054157944],"study_design_scores_gemma":[0.000974664,0.0007121084,0.031760868,0.000016763783,0.00007657489,0.000008985173,0.00008496963,0.00009527928,0.9659736,0.000018687595,0.00007837625,0.0001990961],"about_ca_topic_score_codex":0.00003223775,"about_ca_topic_score_gemma":0.000010580369,"teacher_disagreement_score":0.0068197413,"about_ca_system_score_codex":0.000021547536,"about_ca_system_score_gemma":0.00011713576,"threshold_uncertainty_score":0.99999946},"labels":[],"label_agreement":null},{"id":"W2080806194","doi":"10.1159/000131371","title":"Studies on isolated cloned populations from irradiated human embryonic cell cultures","year":2008,"lang":"en","type":"article","venue":"Cytogenetics and Cell Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Biology; Chromosomal translocation; Karyotype; Molecular biology; Chromosome; Fibroblast; Genetics; Embryonic stem cell; Cloning (programming); Cell culture; Strain (injury); Cell; Gene; Anatomy","score_opus":0.03320968808079891,"score_gpt":0.32319381521010027,"score_spread":0.28998412712930133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080806194","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9722025,0.026004251,0.0005540999,0.000036953017,0.00032623354,0.00022922477,0.00006484369,0.000033087177,0.0005488255],"genre_scores_gemma":[0.9871274,0.008722933,0.0021287948,0.00018784564,0.00031406514,0.000018259028,0.00031955462,0.00006613185,0.0011150159],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844766,0.00005069197,0.00036572057,0.0005806962,0.00018455178,0.00037068198],"domain_scores_gemma":[0.99902636,0.000016108106,0.00011146611,0.0005316244,0.00012123982,0.00019320061],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006088782,0.0003659984,0.00027870495,0.000071124734,0.0003741743,0.000030762156,0.00020736307,0.00025768767,0.000014218938],"category_scores_gemma":[0.000016512913,0.00036310035,0.00010898535,0.000128976,0.0001460265,0.0000019837275,0.00015116588,0.0001522791,0.00001529545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003149235,0.00011907851,0.008428537,0.000025810596,0.00007895927,0.000012213366,0.0004464507,0.008071882,0.9804847,0.000025075626,0.0021155959,0.00016020592],"study_design_scores_gemma":[0.0012265715,0.0008630626,0.021329613,0.000018031422,0.00011545827,0.000015692318,0.00029572353,0.0008053945,0.96585894,0.00018122402,0.008638926,0.00065138773],"about_ca_topic_score_codex":0.000012475216,"about_ca_topic_score_gemma":0.000045566994,"teacher_disagreement_score":0.017281316,"about_ca_system_score_codex":0.000016452328,"about_ca_system_score_gemma":0.000041236217,"threshold_uncertainty_score":0.9998821},"labels":[],"label_agreement":null},{"id":"W2082148793","doi":"10.1073/pnas.0807484105","title":"Recombination between inverted <i>loxP</i> sites is cytotoxic for proliferating cells and provides a simple tool for conditional cell ablation","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Cre recombinase; Cre-Lox recombination; Biology; Genetics; Homologous recombination; Gene targeting; Transgene; Cell biology; Computational biology; Genetically modified mouse; DNA; Gene","score_opus":0.03083535696141822,"score_gpt":0.3097257603282349,"score_spread":0.2788904033668167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082148793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99824566,0.00006138463,0.00066491036,0.00037454977,0.000004272776,0.00046890118,0.00010797204,0.0000037963682,0.000068551584],"genre_scores_gemma":[0.99450636,0.000018547711,0.0051094424,0.00013035598,0.000091466056,0.000052156087,0.000015192952,0.000004488764,0.00007200438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993051,0.0000023443429,0.00019767773,0.00017931907,0.00022275199,0.00009279159],"domain_scores_gemma":[0.9995148,0.00005762559,0.00016927287,0.000005751241,0.00023566253,0.000016851931],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038794527,0.00006688259,0.00008283762,0.000048498005,0.0001959229,0.00001207147,0.00013477034,0.000069991285,0.0000010530748],"category_scores_gemma":[0.00021920432,0.000054315402,0.000046331526,0.00011035364,0.0001586777,0.000025427305,0.00003646147,0.000032528853,5.987616e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010438883,0.000012958392,0.008959209,0.000102490594,0.00000791708,2.9709313e-10,0.00007360332,0.00017675602,0.98775584,0.00040039053,0.0024252506,0.00007515824],"study_design_scores_gemma":[0.00030336814,0.00011601891,0.013220038,0.000008005139,0.0000093775125,0.0000016435121,0.00002697327,0.0063601425,0.97057563,0.008891494,0.00041880252,0.000068504],"about_ca_topic_score_codex":7.023523e-7,"about_ca_topic_score_gemma":4.2891273e-8,"teacher_disagreement_score":0.017180197,"about_ca_system_score_codex":0.0000070192887,"about_ca_system_score_gemma":0.000025055147,"threshold_uncertainty_score":0.22149178},"labels":[],"label_agreement":null},{"id":"W2082565074","doi":"10.1093/nar/gkp112","title":"Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells","year":2009,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Biology; Transgene; Gene targeting; Gene; Transgenesis; Gene knockin; Phenotype; Embryonic stem cell; Cloning (programming); Complementary DNA; Locus (genetics); Cre recombinase; Cell biology; Genetics; Molecular biology; Genetically modified mouse; Computational biology; Embryogenesis","score_opus":0.021545110853778183,"score_gpt":0.334855798846503,"score_spread":0.3133106879927248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082565074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99033415,0.0017275381,0.0073413528,0.000053685253,0.00006935784,0.0002166574,0.000014974257,0.00002689059,0.0002153614],"genre_scores_gemma":[0.99629587,0.00021575761,0.0030662827,0.00002883917,0.00017486783,0.000004930195,0.000016127024,0.00003642361,0.00016089466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827814,0.00009185503,0.00021584844,0.0004555296,0.00035343439,0.0006051622],"domain_scores_gemma":[0.9993335,0.000024190762,0.000024429484,0.00030777502,0.00012360656,0.00018647389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055093796,0.00018327782,0.00017589958,0.0001375699,0.00024681038,0.00007643025,0.00020914401,0.000106827334,0.000031393723],"category_scores_gemma":[0.00005889206,0.00018114405,0.00007171456,0.00020107266,0.00011160118,0.0000030848266,0.000090774054,0.00020939964,0.0000096326785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043739128,0.000058243644,0.00018630117,0.000031221145,0.000016084474,0.000007593038,0.00013146707,0.023614973,0.9728173,0.000010868936,0.0002885403,0.0027936888],"study_design_scores_gemma":[0.00035684524,0.0002613461,0.00056301133,0.000017415668,0.000008758815,0.0000098149,0.00018175965,0.01851111,0.9777315,0.000012463689,0.0021295522,0.00021642075],"about_ca_topic_score_codex":0.00003851994,"about_ca_topic_score_gemma":0.000002419183,"teacher_disagreement_score":0.0059616948,"about_ca_system_score_codex":0.000030259558,"about_ca_system_score_gemma":0.000052829397,"threshold_uncertainty_score":0.738684},"labels":[],"label_agreement":null},{"id":"W2084545410","doi":"10.1038/nrg2317","title":"The ethics of human gene transfer","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"U.S. Food and Drug Administration","keywords":"Biology; Context (archaeology); Gene transfer; Germline; Character (mathematics); Engineering ethics; Face (sociological concept); Field (mathematics); Genetics; Computational biology; Gene; Biotechnology; Sociology; Social science; Engineering","score_opus":0.042663515891509886,"score_gpt":0.4205801533607986,"score_spread":0.3779166374692887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084545410","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000096376925,0.9972442,0.00091072766,0.00001861633,0.0004302412,0.0010089192,0.000050874216,0.000008949731,0.00031783778],"genre_scores_gemma":[0.000022730135,0.9975833,0.0007242772,0.000068945454,0.00070519693,0.00008904836,0.00028196603,0.000104130064,0.00042038207],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973438,0.00037912157,0.001085619,0.0005131981,0.00030762004,0.0003706675],"domain_scores_gemma":[0.9981584,0.00008950576,0.00023345853,0.0012651521,0.00014880653,0.00010470666],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000608338,0.00057870324,0.0014079275,0.000060962953,0.00022209156,0.000019554445,0.00085291377,0.0020655065,0.000006084628],"category_scores_gemma":[0.00020869417,0.00037617542,0.0011482212,0.00024659422,0.00017601553,8.1562223e-7,0.00013986803,0.0017342642,0.0000112988955],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000020800462,0.000026240748,9.16933e-7,0.007427074,0.00018745915,0.000003591655,0.00003042534,0.0000057442644,0.0015453314,0.00008240566,0.0039223568,0.9867664],"study_design_scores_gemma":[0.00008908661,0.000114939554,0.0000014459947,0.0017543514,0.00035303904,0.00012885017,0.0000018531879,6.8326636e-7,0.0031098635,0.000007965409,0.9940556,0.00038228024],"about_ca_topic_score_codex":9.64459e-7,"about_ca_topic_score_gemma":0.000016396389,"teacher_disagreement_score":0.9901333,"about_ca_system_score_codex":0.000018984232,"about_ca_system_score_gemma":0.00026071694,"threshold_uncertainty_score":0.999869},"labels":[],"label_agreement":null},{"id":"W2084929545","doi":"10.1002/biot.200800163","title":"Can policy actors agree on biotechnology","year":2008,"lang":"en","type":"article","venue":"Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Citation; Library science; Citation impact; Political science; Sociology; Computer science","score_opus":0.009364035840608912,"score_gpt":0.27526847675069765,"score_spread":0.26590444091008875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084929545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97835696,0.00093177496,0.005410296,0.014140646,0.00040749108,0.00009605047,0.000011069927,0.000113064656,0.00053262484],"genre_scores_gemma":[0.9936753,0.003622729,0.0012076611,0.00043744364,0.000587,0.0000048672764,0.000009299973,0.000034493554,0.0004212254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987784,0.00002482709,0.00025028738,0.00032528918,0.00012813603,0.0004930788],"domain_scores_gemma":[0.9992346,0.000007541566,0.00009698262,0.0004970125,0.000042074214,0.00012178286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103820596,0.00022955339,0.00019625368,0.0004691394,0.00024881726,0.000011335402,0.0004670212,0.00094245974,0.000021535305],"category_scores_gemma":[0.00022453979,0.00021054092,0.00012603134,0.0002803268,0.00031847338,0.0000020741104,0.0001445843,0.0006092917,0.000030001567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044255943,0.000067415436,0.0012481263,0.0000039284914,0.00008961506,0.00011969784,0.000031956202,0.00014748181,0.9766212,0.0017430484,0.0051693856,0.014713881],"study_design_scores_gemma":[0.0005408885,0.0007358309,0.003197128,0.000010106848,0.000008432666,0.0042102356,0.00005274302,0.000015247212,0.8842613,0.00027082465,0.10644438,0.00025287294],"about_ca_topic_score_codex":0.000016816755,"about_ca_topic_score_gemma":0.000022035158,"teacher_disagreement_score":0.101275,"about_ca_system_score_codex":0.00005159265,"about_ca_system_score_gemma":0.0001706077,"threshold_uncertainty_score":0.8585609},"labels":[],"label_agreement":null},{"id":"W2085106837","doi":"10.1074/jbc.m808598200","title":"The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Phosphorylation; Effector; Inhibitory postsynaptic potential; Cyclin-dependent kinase 1; Chemistry; Cell biology; Biochemistry; Biology; Neuroscience; Gene; Cell cycle","score_opus":0.010528257641164149,"score_gpt":0.2665905418540961,"score_spread":0.2560622842129319,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085106837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894092,0.0018277558,0.008056786,0.000036903766,0.00018891213,0.000078806785,0.000002325037,0.000008693083,0.00039062576],"genre_scores_gemma":[0.9981616,0.000395173,0.00052627194,0.000022771967,0.00067771453,0.0000054043553,0.0000092250375,0.000012335385,0.00018947783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989322,0.000056039382,0.0003543197,0.00020112965,0.00018416446,0.0002721863],"domain_scores_gemma":[0.9992378,0.00007282604,0.00029080128,0.00018239679,0.00009471878,0.00012145997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005394841,0.00017292859,0.0002019831,0.000011078072,0.00020109891,0.000019005513,0.00020310619,0.00022509089,0.000022776638],"category_scores_gemma":[0.00019253317,0.00011428344,0.00021010627,0.00003913189,0.00007978868,0.000005761364,0.000101398604,0.00028891358,0.0000020432276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018192598,0.000040076367,0.011781773,0.000014271369,0.000054737557,0.000044929035,0.00002293302,0.00011903705,0.98525137,8.2869394e-7,0.00010426706,0.0023838712],"study_design_scores_gemma":[0.00044393193,0.00027654428,0.017851472,0.000021228603,0.000014058219,0.00068676204,0.00004867902,0.000024393186,0.9775997,0.00006219704,0.0028152568,0.00015580867],"about_ca_topic_score_codex":0.0000022155175,"about_ca_topic_score_gemma":5.878202e-7,"teacher_disagreement_score":0.0087524345,"about_ca_system_score_codex":0.000041282987,"about_ca_system_score_gemma":0.000066313536,"threshold_uncertainty_score":0.46603435},"labels":[],"label_agreement":null},{"id":"W2085494583","doi":"10.1038/embor.2011.35","title":"The ‘National’ and the ‘Cosmos’","year":2011,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for International Governance Innovation","funders":"","keywords":"Cosmos (plant); Biology; Genetics","score_opus":0.011613835719257228,"score_gpt":0.2731232433801327,"score_spread":0.2615094076608755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085494583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85906494,0.008101365,0.0028599324,0.00073111756,0.00063063094,0.00030886394,0.0000016065745,0.00002176839,0.12827979],"genre_scores_gemma":[0.99748105,0.00016734413,0.00015292081,0.00013872406,0.0001050766,0.000014232118,0.0000027420479,0.000005578823,0.0019323267],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996421,0.000011814193,0.000098702105,0.00010288847,0.0000689944,0.000075542775],"domain_scores_gemma":[0.9997565,0.000010263643,0.000032931453,0.00014657914,0.00003379117,0.000019914189],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030315883,0.00004563059,0.00003575769,0.000004193206,0.00008751289,0.000012448284,0.000043786808,0.000026196702,0.000010203077],"category_scores_gemma":[0.00010297592,0.000024353902,0.000027274058,0.000018077568,0.00007203391,6.4131564e-7,0.00004453654,0.000029460305,0.0000017195526],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008455337,0.00026829378,0.04884541,0.00009889954,0.0013718951,0.00032411964,0.0061288467,0.000697371,0.37770307,0.0434014,0.4337055,0.086609624],"study_design_scores_gemma":[0.00054426456,0.00006416056,0.058570046,0.0000067431615,0.000028424034,0.00093486474,0.00014796336,0.00012866221,0.164185,0.0083449455,0.76681775,0.00022719134],"about_ca_topic_score_codex":0.000009539019,"about_ca_topic_score_gemma":0.000009094017,"teacher_disagreement_score":0.3331122,"about_ca_system_score_codex":0.0000015594352,"about_ca_system_score_gemma":0.00001360695,"threshold_uncertainty_score":0.09931233},"labels":[],"label_agreement":null},{"id":"W2086098426","doi":"10.1073/pnas.0405762101","title":"Mixing active-site components: A recipe for the unique enzymatic activity of a telomere resolvase","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Tn3 transposon; Recombinase; Transposase; Biology; Telomere; DNA; Active site; Nuclease; Binding site; Mutant; Biochemistry; Genetics; Enzyme; Transposable element; Recombination; Gene","score_opus":0.03176403389846679,"score_gpt":0.33254360986296794,"score_spread":0.30077957596450117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086098426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977725,0.00021243011,0.0003030947,0.0011412189,0.000013172462,0.00022721059,0.000022925728,0.0000023372545,0.0003051088],"genre_scores_gemma":[0.99719995,0.000044384153,0.0026099968,0.000057192876,0.00004401248,0.000016181291,2.6850032e-7,0.0000034906082,0.00002449611],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929655,0.0000033933966,0.00015913151,0.00014013705,0.0003039998,0.00009681741],"domain_scores_gemma":[0.99954474,0.00006456227,0.00020467494,0.000012447647,0.00015677529,0.00001681844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056982733,0.00006590433,0.000094350646,0.00004593188,0.00010600905,0.000006599694,0.0003821936,0.000058120266,9.8316e-7],"category_scores_gemma":[0.00038567855,0.000040950494,0.000076304306,0.0002142485,0.0003058045,0.000013470758,0.00009406058,0.000067851215,7.3338654e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003840446,0.000027855584,0.00021167302,0.00006761131,0.000019947576,8.961705e-10,0.00011605092,0.001411969,0.9958439,0.0018154011,0.000048057125,0.00039914448],"study_design_scores_gemma":[0.00021589496,0.00006349866,0.014674068,0.000072745825,0.000012151955,0.000003029894,0.000093346185,0.0006196619,0.98077023,0.0032176704,0.00020988662,0.000047829082],"about_ca_topic_score_codex":0.000010181686,"about_ca_topic_score_gemma":3.4590983e-7,"teacher_disagreement_score":0.015073669,"about_ca_system_score_codex":0.000012428849,"about_ca_system_score_gemma":0.000029145553,"threshold_uncertainty_score":0.16699126},"labels":[],"label_agreement":null},{"id":"W2086246079","doi":"10.1038/nbt1204supp-dc8","title":"The scientific muscle of Brazil's health biotechnology","year":2004,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; University of Toronto","funders":"","keywords":"Biotechnology; Business; Biology","score_opus":0.003191177234192447,"score_gpt":0.29077868272413177,"score_spread":0.28758750548993933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086246079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8975949,0.039204948,0.018765455,0.041842118,0.0016909835,0.00044405035,0.00003304369,0.00019446241,0.00023003174],"genre_scores_gemma":[0.995882,0.0011773825,0.0024253638,0.00023312167,0.00006808617,0.000009390421,0.00002474569,0.000019954552,0.00015995605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880254,0.000016830485,0.00024336913,0.0004177213,0.0001224808,0.0003970817],"domain_scores_gemma":[0.99892217,0.000010993265,0.000106662956,0.0008550631,0.00005944291,0.000045653014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000297525,0.0001496848,0.00016730293,0.00014829956,0.00023519214,0.00001692855,0.0005668173,0.0012068661,0.0000026696082],"category_scores_gemma":[0.00019479345,0.00011642864,0.00008382049,0.00041848037,0.0006684685,0.0000017711263,0.00023275816,0.00051844685,0.000006896593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011802442,0.000033936405,0.00002258879,0.000014195486,0.000024919009,0.0000013527857,0.000013621928,0.0001153857,0.94933254,0.020702617,0.0016017853,0.028125275],"study_design_scores_gemma":[0.00027271736,0.00022770392,0.00043631735,0.00000876693,0.000003274651,0.000023790155,0.000049460312,0.000005944129,0.70747364,0.0007669992,0.2906405,0.00009090599],"about_ca_topic_score_codex":0.000016163407,"about_ca_topic_score_gemma":0.00020772796,"teacher_disagreement_score":0.28903872,"about_ca_system_score_codex":0.0000253786,"about_ca_system_score_gemma":0.00015938707,"threshold_uncertainty_score":0.9308456},"labels":[],"label_agreement":null},{"id":"W2086885866","doi":"10.1021/ja408729b","title":"Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from <i>Sulfolobus solfataricus</i>","year":2013,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health; Department of Energy, Labor and Economic Growth","keywords":"Sulfolobus solfataricus; Chemistry; Nuclease; Sulfolobus; CRISPR; Cluster (spacecraft); DNA; Cleavage (geology); Computational biology; Stereochemistry; Biochemistry; Archaea; Gene","score_opus":0.0031464667340433705,"score_gpt":0.22766856704997743,"score_spread":0.22452210031593406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086885866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962518,0.0010643108,0.0003128178,0.0020312842,0.00013069721,0.0001041609,0.000063469844,0.000006112068,0.00003530547],"genre_scores_gemma":[0.99535465,0.00016212263,0.00052606355,0.0034978364,0.00036616903,0.0000023646476,0.000015542963,0.000025838952,0.00004938526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892247,0.000062573155,0.0003101552,0.00019295463,0.00022805166,0.00028381098],"domain_scores_gemma":[0.99906665,0.00007605503,0.0003800534,0.00025150552,0.0000926349,0.00013312574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001423998,0.00019044946,0.00027117596,0.000004737993,0.00011978584,0.000065109685,0.00040309122,0.00012043734,0.000023482065],"category_scores_gemma":[0.00014916388,0.00011300952,0.00028338263,0.00009077627,0.00028037233,0.00000968865,0.00023638371,0.0004119692,9.733711e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003733066,0.000024719171,0.0013815786,0.0000027171293,0.00017540246,5.8892317e-7,0.00022963768,0.000026365795,0.87896127,3.5993577e-7,0.11820394,0.0009560725],"study_design_scores_gemma":[0.0010896241,0.00019200977,0.008289215,0.000022290433,0.00014071114,0.000065898406,0.0014884956,0.00037427625,0.978156,0.00008593362,0.009820042,0.00027555018],"about_ca_topic_score_codex":0.0004341431,"about_ca_topic_score_gemma":0.000009768287,"teacher_disagreement_score":0.108383894,"about_ca_system_score_codex":0.000051918047,"about_ca_system_score_gemma":0.000037629616,"threshold_uncertainty_score":0.46083945},"labels":[],"label_agreement":null},{"id":"W2087175689","doi":"10.1016/j.yjmcc.2007.03.176","title":"Lentivirus vector-mediated SERCA2 gene transfer ameliorates heart failure induced by myocardial infarction in rat","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Heart failure; Genetic enhancement; Myocardial infarction; Cardiology; Internal medicine; Medicine; Diastole; Cardiac function curve; Gene delivery; Blood pressure; Gene; Biology","score_opus":0.0047248078297664284,"score_gpt":0.23406505390996274,"score_spread":0.22934024608019632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087175689","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94427824,0.0073198797,0.047755554,0.00014382396,0.00034899582,0.00010556461,0.0000060517236,0.0000044629733,0.000037422327],"genre_scores_gemma":[0.99885887,0.000349485,0.00024824825,0.000168594,0.0002903772,0.0000025325635,0.00004956722,0.000025472651,0.0000068337117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876356,0.00013856396,0.0004090196,0.00022876478,0.00014994394,0.00031014913],"domain_scores_gemma":[0.99954164,0.000018848012,0.000056928875,0.0001536124,0.000099374,0.00012958776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006386013,0.00019171419,0.00038225146,0.00014986073,0.00003240079,0.000015925478,0.000101387304,0.00031986638,0.0000036332217],"category_scores_gemma":[0.000048873575,0.00018638176,0.0002585741,0.00014119661,0.000052674324,0.000007290551,0.000033292148,0.00028824073,0.0000015082832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013715876,0.00001853566,0.00326018,0.0000096353615,0.00016736194,0.00008739038,0.00003690626,0.00044781578,0.99512285,0.000005058392,0.0003359478,0.00037115958],"study_design_scores_gemma":[0.0011528799,0.00045449875,0.0036691849,0.000010287189,0.000059625865,0.0003071935,0.00011259255,0.000008609795,0.98067147,0.000013342965,0.013338487,0.00020180682],"about_ca_topic_score_codex":0.000010751489,"about_ca_topic_score_gemma":0.000012904876,"teacher_disagreement_score":0.054580647,"about_ca_system_score_codex":0.000020091238,"about_ca_system_score_gemma":0.00004845445,"threshold_uncertainty_score":0.7600427},"labels":[],"label_agreement":null},{"id":"W2087966448","doi":"10.1007/s11103-006-9004-3","title":"Self-excision of the antibiotic resistance gene nptII using a heat inducible Cre-loxP system from transgenic potato","year":2006,"lang":"en","type":"article","venue":"Plant Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Biology; Selectable marker; Gene; Cre recombinase; Kanamycin; Transformation (genetics); Marker gene; Genetics; Transgene; Transposase; Cre-Lox recombination; Molecular biology; Transposable element; Genome; Genetically modified mouse","score_opus":0.00590662898390376,"score_gpt":0.2582523717733616,"score_spread":0.2523457427894578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087966448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9307202,0.005283931,0.06297807,0.000032889002,0.00022174146,0.00023773129,0.00023832545,0.000025301286,0.0002618052],"genre_scores_gemma":[0.9916474,0.00007866434,0.007729878,0.000041187028,0.00013440679,0.000003933964,0.0003095605,0.000030203357,0.000024762068],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861825,0.00012862888,0.0003544613,0.00046365557,0.000115578594,0.00031940764],"domain_scores_gemma":[0.99923396,0.00001704112,0.00008401519,0.00056502566,0.00005051268,0.000049445578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013387126,0.00022309629,0.00027288008,0.000054237484,0.00007710852,0.000010842907,0.0003071127,0.00027041193,0.0000030713857],"category_scores_gemma":[0.000016083079,0.00017913144,0.00016879251,0.0001512758,0.000056789177,0.0000018912909,0.00009900684,0.00010516701,0.0000021878575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004523648,0.000039392286,0.0014727183,0.000060012117,0.00007712726,0.000009016515,0.000019590732,0.0014445957,0.9964379,0.000312849,0.0000596523,0.000021926982],"study_design_scores_gemma":[0.00046642567,0.00007035939,0.0018325497,0.000056013043,0.00007775032,0.000043869273,0.000024475616,0.0010890566,0.9935373,0.00005770719,0.002525341,0.00021911664],"about_ca_topic_score_codex":0.0002910492,"about_ca_topic_score_gemma":0.000115263894,"teacher_disagreement_score":0.060927194,"about_ca_system_score_codex":0.000027280463,"about_ca_system_score_gemma":0.00006443942,"threshold_uncertainty_score":0.7304768},"labels":[],"label_agreement":null},{"id":"W2088194014","doi":"10.1158/1538-7445.am2013-lb-234","title":"Abstract LB-234: A comparative genomic approach for identifying synthetic lethal interactions in human cancer.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Synthetic lethality; Olaparib; Computational biology; Biology; Cancer; PARP inhibitor; CRISPR; Model organism; Yeast; Small hairpin RNA; Cancer cell; Genetics; Cancer research; Mutant; Gene; RNA; Poly ADP ribose polymerase; Polymerase","score_opus":0.15724096308421256,"score_gpt":0.501505030764063,"score_spread":0.3442640676798505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088194014","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99246526,0.0018093031,0.003517191,0.000087028835,0.00011185041,0.00070794416,0.000026815042,0.00000776533,0.00126685],"genre_scores_gemma":[0.9962797,0.00013217983,0.00046235466,0.000013633079,0.00028102996,0.0020021412,0.00004572271,0.000024018755,0.000759177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887794,0.00004054392,0.00018369421,0.00035688514,0.00013305902,0.00040786847],"domain_scores_gemma":[0.9994817,0.000033537857,0.00002851248,0.00022821932,0.00014603935,0.00008201725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026481028,0.00011355692,0.00014345221,0.00012189252,0.00014002864,0.000066775414,0.00022497051,0.000058800473,0.00020120227],"category_scores_gemma":[0.000023024393,0.00011584804,0.0000620332,0.00012151269,0.00008677728,0.000007748143,0.00009693482,0.00026075912,0.000010074233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002059671,0.000043794902,0.0004558366,0.00008921867,0.000035850662,5.76973e-7,0.00037572795,0.005033729,0.99051684,0.000022203263,0.0023123035,0.0010933134],"study_design_scores_gemma":[0.0009472578,0.0001081853,0.031719945,0.0001271051,0.000012286463,0.0000062350264,0.0021246043,0.0030361614,0.9545561,0.0001394593,0.0068458817,0.00037675817],"about_ca_topic_score_codex":0.0022509038,"about_ca_topic_score_gemma":0.0011177722,"teacher_disagreement_score":0.03596073,"about_ca_system_score_codex":0.00012045912,"about_ca_system_score_gemma":0.00009658313,"threshold_uncertainty_score":0.47241458},"labels":[],"label_agreement":null},{"id":"W2089885698","doi":"10.1016/j.cell.2010.09.023","title":"ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner","year":2010,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":436,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome British Columbia; University of British Columbia","funders":"","keywords":"Biology; Allele; Tandem repeat; Genetics; Computational biology; Gene; Genome","score_opus":0.004689077131513344,"score_gpt":0.23756419201336654,"score_spread":0.2328751148818532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089885698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99670875,0.002095057,0.0002853888,0.00004011676,0.000100701676,0.00020064271,0.0000024447736,0.000011468502,0.0005554436],"genre_scores_gemma":[0.9965669,0.00016391605,0.0019557306,0.000021739275,0.0000707905,0.0000321654,0.000009867439,0.000016455506,0.0011624704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992484,0.00001600916,0.00014688364,0.00030915978,0.000087881635,0.0001916954],"domain_scores_gemma":[0.9996326,0.0000070145115,0.00003139158,0.00023837159,0.000018047695,0.0000725905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011770503,0.00012357859,0.00010335363,0.000027004055,0.0000348042,0.000021170461,0.000109229906,0.00014666127,0.000043448235],"category_scores_gemma":[0.000023349017,0.00011221585,0.000028267581,0.0000351127,0.000033643653,0.0000035193495,0.0000942138,0.00014587796,0.000006937885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000124602475,0.00002639553,0.0022256954,0.000019825988,0.00000257254,0.000025452986,0.00005715222,0.000084508116,0.9970589,0.0000024857181,0.00022749016,0.00025704253],"study_design_scores_gemma":[0.0004451496,0.000086990214,0.021847103,0.000017436023,0.0000022029897,0.000032284916,0.00004815206,0.000023652832,0.9609213,0.000050521572,0.01634964,0.00017556614],"about_ca_topic_score_codex":0.000006615595,"about_ca_topic_score_gemma":0.000048912618,"teacher_disagreement_score":0.036137618,"about_ca_system_score_codex":0.000003752005,"about_ca_system_score_gemma":0.000015036866,"threshold_uncertainty_score":0.45760298},"labels":[],"label_agreement":null},{"id":"W2090118739","doi":"10.1139/o2012-006","title":"Random mutagenesis suggests that sequence errors are not a major cause of variation in the activity of individual molecules of β-galactosidase","year":2012,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Winnipeg","funders":"Alexander von Humboldt-Stiftung","keywords":"Plasmid; Beta-galactosidase; Escherichia coli; Biology; Mutagenesis; Genetics; Molecular biology; lac operon; Population; Gene; Directed evolution; Enzyme; Mutation; Biochemistry; Mutant","score_opus":0.01711816765037375,"score_gpt":0.28745403389922036,"score_spread":0.2703358662488466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090118739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971418,0.0016282117,0.0008586335,0.000024385241,0.000036129564,0.00010697808,0.00012564106,0.0000020789735,0.000076158016],"genre_scores_gemma":[0.9994699,0.00019934564,0.00018710564,0.00001948015,0.000037995844,0.000012112028,0.00005420763,0.0000064848336,0.000013419933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930954,0.00008192056,0.00018915755,0.00017529368,0.0000745951,0.0001695035],"domain_scores_gemma":[0.9994552,0.00005460645,0.00018671293,0.00023382301,0.000032058775,0.000037556012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031889015,0.00012605266,0.00019972173,0.000029079134,0.000016990296,0.0000024476908,0.0001573657,0.00020864754,0.000005499695],"category_scores_gemma":[0.000069273185,0.00010037643,0.000059081674,0.00007051155,0.00013822851,0.0000033819306,0.00007043246,0.00006483374,1.12790126e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014525169,0.00011349867,0.02486863,0.00016615451,0.000033437875,5.3639593e-7,0.0002377509,0.00002104534,0.9740671,0.0000053703952,0.000007583781,0.00033366636],"study_design_scores_gemma":[0.0006444884,0.00006992488,0.06790156,0.000014286304,0.000043514105,0.0000065391955,0.00016491863,0.000014782602,0.9310105,0.0000035019816,0.000032523272,0.00009350465],"about_ca_topic_score_codex":0.000042128584,"about_ca_topic_score_gemma":0.000006655403,"teacher_disagreement_score":0.04305662,"about_ca_system_score_codex":0.000003815013,"about_ca_system_score_gemma":0.000027964175,"threshold_uncertainty_score":0.4093232},"labels":[],"label_agreement":null},{"id":"W2090538188","doi":"10.1096/fj.11-198135","title":"Differences in the enzymatic efficiency of human and bony fish AID are mediated by a single residue in the C terminus modulating single‐stranded DNA binding","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Alberta; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Residue (chemistry); Enzyme; Chemistry; DNA; Biochemistry; Fish <Actinopterygii>; Cell biology; Biophysics; Biology; Fishery","score_opus":0.02544748238430909,"score_gpt":0.2546450868248062,"score_spread":0.2291976044404971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090538188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99901175,0.00035570702,0.00014535675,0.000105927385,0.00003157945,0.00011445235,0.0000071745003,0.0000018798811,0.000226188],"genre_scores_gemma":[0.9997961,0.000032653996,0.000041793137,0.000057073346,0.000045779812,0.000003982162,0.00000456089,0.000007295935,0.000010762899],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910927,0.0001680331,0.00027284966,0.000108376036,0.00014971191,0.00019173337],"domain_scores_gemma":[0.99958885,0.00007221903,0.000133909,0.00016404725,0.000016180991,0.000024795665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006706617,0.00010804702,0.00012901533,0.000048616515,0.0001239522,0.00004101224,0.0003164447,0.000055904253,0.000005948211],"category_scores_gemma":[0.00010368788,0.000056605844,0.000038608825,0.00011146654,0.000088321525,0.0000038058067,0.000033309796,0.00019096243,1.4874806e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014779923,0.000081606006,0.010419893,0.000014830176,0.000009895233,0.000011476394,0.0046905656,0.000013471918,0.9844806,0.0000023107173,0.000045913246,0.00021461378],"study_design_scores_gemma":[0.00091596995,0.0004887338,0.059972215,0.00017914758,0.000029624573,0.00024037767,0.00803266,0.00038671534,0.92945385,0.00012457772,0.000010673134,0.00016544889],"about_ca_topic_score_codex":0.000027158732,"about_ca_topic_score_gemma":0.0001850525,"teacher_disagreement_score":0.05502679,"about_ca_system_score_codex":0.0000069967746,"about_ca_system_score_gemma":0.000011393816,"threshold_uncertainty_score":0.23083194},"labels":[],"label_agreement":null},{"id":"W2090946534","doi":"10.1038/nbt.2872","title":"Cas9 in close-up","year":2014,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Endonuclease; Cas9; Computational biology; CRISPR; Biology; DNA; Genetics; Gene","score_opus":0.0021747455801670295,"score_gpt":0.26959599942859763,"score_spread":0.26742125384843063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090946534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869913,0.0029242993,0.0057993964,0.0014852462,0.00068758987,0.000114308335,0.0000040884543,0.00006982661,0.0019239549],"genre_scores_gemma":[0.99777,0.00014779327,0.0010760498,0.00031048612,0.00015568394,0.0000074556274,0.00001858379,0.00001545497,0.00049848383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993114,0.000015136152,0.00010892933,0.0002914867,0.000051965853,0.00022108866],"domain_scores_gemma":[0.9995622,0.0000066720454,0.00002042514,0.00036683853,0.00001631418,0.000027539678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112582406,0.000108953674,0.00010864336,0.00010257473,0.00001793143,0.0000047234093,0.000198423,0.0012223154,0.000008360898],"category_scores_gemma":[0.00016372403,0.00010692537,0.00003684842,0.00013456972,0.000050105486,7.761447e-7,0.00009329915,0.00041731517,0.000013075563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018863328,0.000017983148,0.0011180271,0.000010801435,0.000010327666,0.0000035558498,0.000008836976,0.00003076708,0.96330845,0.012528635,0.0019232248,0.021020548],"study_design_scores_gemma":[0.00031623532,0.00010221602,0.0016861921,0.00000469829,0.000002608141,0.000024131383,0.000011837377,0.00007146393,0.64329207,0.00043933486,0.35392648,0.0001227321],"about_ca_topic_score_codex":0.000006672641,"about_ca_topic_score_gemma":0.00009960389,"teacher_disagreement_score":0.35200328,"about_ca_system_score_codex":0.000007894506,"about_ca_system_score_gemma":0.000012481263,"threshold_uncertainty_score":0.94276154},"labels":[],"label_agreement":null},{"id":"W2090957277","doi":"10.1111/j.1365-2516.2007.01567.x","title":"Staunch protections: the ethics of haemophilia gene transfer research","year":2007,"lang":"en","type":"review","venue":"Haemophilia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"University of Pennsylvania","keywords":"Haemophilia; Medicine; Clinical trial; Disadvantaged; Gene transfer; Law; Pediatrics; Political science; Pathology","score_opus":0.20612550899007243,"score_gpt":0.4972051936361133,"score_spread":0.2910796846460409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090957277","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010721876,0.99018997,0.00682415,0.000120705234,0.0003680286,0.0016008017,0.00010908719,0.000019094796,0.00066096464],"genre_scores_gemma":[0.00070937123,0.99628085,0.0003760773,0.00003324749,0.0008061322,0.00023573411,0.00016622267,0.00010633917,0.0012860515],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99694514,0.00047771548,0.0007241948,0.000634316,0.0006373761,0.00058126525],"domain_scores_gemma":[0.9979562,0.00021071313,0.000079878824,0.001246605,0.00039049433,0.000116066105],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0031347156,0.00042274556,0.00078776694,0.00023882587,0.0002572667,0.00003043637,0.0007606835,0.0011064933,0.0000354797],"category_scores_gemma":[0.00043053733,0.0003021591,0.00055219774,0.00064380094,0.0003850836,0.0000022223062,0.00021027014,0.0017870897,0.00002883694],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045702014,0.00014354687,0.0000019720333,0.016015103,0.0005435733,0.000024664225,0.00035786253,0.00009679648,0.005703044,0.00044592487,0.0028828515,0.97373897],"study_design_scores_gemma":[0.00012888105,0.00019479694,0.0000043118093,0.0013535371,0.00016641733,0.00009890269,0.000038764614,0.000004236894,0.011048156,0.000105634295,0.9865465,0.00030984927],"about_ca_topic_score_codex":0.000041200223,"about_ca_topic_score_gemma":0.00005720259,"teacher_disagreement_score":0.9836637,"about_ca_system_score_codex":0.000044572473,"about_ca_system_score_gemma":0.0005392584,"threshold_uncertainty_score":0.9999431},"labels":[],"label_agreement":null},{"id":"W2091131497","doi":"10.1002/rmv.316","title":"Silencing of gene expression: implications for design of retrovirus vectors","year":2001,"lang":"en","type":"review","venue":"Reviews in Medical Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Biology; RNA interference; DNA methylation; Retrovirus; Vector (molecular biology); Viral vector; Transgene; Genetics; Gene; Cell biology; Gene expression; RNA","score_opus":0.061976307041964954,"score_gpt":0.4162775651591377,"score_spread":0.3543012581171728,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091131497","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000246169,0.844398,0.15449195,0.000015246935,0.0001204135,0.00089139515,0.000022740534,0.0000028694446,0.000032745327],"genre_scores_gemma":[0.000053989977,0.9896355,0.0094453925,0.00004149365,0.00021568751,0.00043730103,0.00011988386,0.000032473963,0.000018227745],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977314,0.0003089509,0.0012104134,0.00039114288,0.000105243395,0.0002528886],"domain_scores_gemma":[0.9986715,0.00021797554,0.0004195166,0.00055394357,0.000037416183,0.00009967043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010785287,0.0002537539,0.0016538388,0.00010952082,0.000016080257,0.0000012200711,0.00045096045,0.0007082141,0.00005999031],"category_scores_gemma":[0.0014341407,0.00020072387,0.0003967794,0.00020287887,0.000108369466,0.0000010022252,0.00009275474,0.00021018983,0.0000020284735],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011732197,0.000060002858,0.000017425846,0.008876296,0.000044007353,0.0000015562853,0.000009093896,0.000033734585,0.017966487,0.000022078373,0.000846192,0.9721114],"study_design_scores_gemma":[0.00021708626,0.0002540276,0.000012659488,0.004058401,0.00016705134,0.000049928844,0.0000016277598,0.000012996898,0.0023911863,0.000020865547,0.9926282,0.00018596339],"about_ca_topic_score_codex":0.0000027227006,"about_ca_topic_score_gemma":0.000002527785,"teacher_disagreement_score":0.991782,"about_ca_system_score_codex":0.00001726993,"about_ca_system_score_gemma":0.00020735837,"threshold_uncertainty_score":0.8185282},"labels":[],"label_agreement":null},{"id":"W2091214983","doi":"10.1038/mt.2013.161","title":"Toward Position-independent Retroviral Vector Expression in Pluripotent Stem Cells","year":2013,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biology; Gene silencing; DNA methylation; CTCF; Epigenetics; Retrovirus; Genetics; Chromatin; Molecular biology; Viral vector; Transgene; Gene; Gene expression; Enhancer","score_opus":0.009547279792562782,"score_gpt":0.2446785683264336,"score_spread":0.2351312885338708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091214983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82913035,0.02831217,0.05377756,0.08157243,0.0029780273,0.0031064034,0.00016193827,0.00014065384,0.0008204477],"genre_scores_gemma":[0.75474083,0.0027441783,0.0017161663,0.23107216,0.0033625707,0.00048354195,0.0014181263,0.00044049797,0.004021938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979273,0.00013098524,0.00034883115,0.00071273826,0.00037387415,0.00050624844],"domain_scores_gemma":[0.99905473,0.0000075119883,0.00010507183,0.0006965965,0.00006069151,0.000075422235],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000098985074,0.00046341735,0.00033502345,0.00012838111,0.00003487879,0.000069757625,0.0004104452,0.0009605237,0.00008019149],"category_scores_gemma":[0.000002956547,0.00044461188,0.0002632829,0.000080212434,0.000032301825,0.0000036520942,0.00011234652,0.0007185531,0.000057350273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032284326,0.0000324837,0.000015139042,0.000044537486,0.000057973968,0.0002771448,0.00004815718,0.00033431975,0.9123709,0.0000010428528,0.085367575,0.0014184272],"study_design_scores_gemma":[0.0006414262,0.00022739144,0.00007388326,0.000058205253,0.000008605659,0.000018939685,0.000011012494,0.000034593155,0.7667532,0.00001497825,0.23173386,0.00042391696],"about_ca_topic_score_codex":0.000032857235,"about_ca_topic_score_gemma":0.0000019553952,"teacher_disagreement_score":0.14949973,"about_ca_system_score_codex":0.00006253564,"about_ca_system_score_gemma":0.000057739257,"threshold_uncertainty_score":0.99980056},"labels":[],"label_agreement":null},{"id":"W2091942994","doi":"10.1042/bj20041822","title":"Exploring the functions of RNA interference pathway proteins: some functions are more RISCy than others?","year":2005,"lang":"en","type":"review","venue":"Biochemical Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Dicer; RNA interference; Biology; Gene silencing; Small interfering RNA; RasiRNA; Argonaute; microRNA; Piwi-interacting RNA; RNA-induced silencing complex; Computational biology; RNA silencing; Trans-acting siRNA; Cell biology; Genetics; Gene; RNA","score_opus":0.06830041006848636,"score_gpt":0.3247696906593308,"score_spread":0.25646928059084445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091942994","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0045322753,0.9900839,0.00410681,0.000095386684,0.0006204749,0.00034328114,0.00010626534,0.000015851017,0.00009580513],"genre_scores_gemma":[0.011586033,0.98461527,0.00022796079,0.000021694563,0.0027505772,0.00014679198,0.000071374925,0.000065501525,0.00051479135],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983702,0.0000754907,0.0006328821,0.00036264566,0.00022048647,0.0003382984],"domain_scores_gemma":[0.9987715,0.000028756951,0.00039203878,0.00052908604,0.00011331472,0.0001652935],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021581077,0.00039250852,0.0005849981,0.00010944534,0.00014627667,0.00005362269,0.0005200221,0.00023888613,0.000034890327],"category_scores_gemma":[0.00013790905,0.0002623654,0.00068751816,0.00017808408,0.00012510369,0.000012427001,0.00018600021,0.00073517684,0.000018032382],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038638726,0.000183738,0.000008112446,0.0016739274,0.00071890076,0.000008956258,0.00010630328,0.000069479036,0.06608342,0.000011716494,0.0044647832,0.92663205],"study_design_scores_gemma":[0.00020200259,0.00014054369,0.000027101723,0.0034063782,0.0003203706,0.000345424,0.00030722315,0.000005509526,0.021712305,0.000005266002,0.9731071,0.00042075268],"about_ca_topic_score_codex":0.0000039513425,"about_ca_topic_score_gemma":0.000002670668,"teacher_disagreement_score":0.96864235,"about_ca_system_score_codex":0.000051271727,"about_ca_system_score_gemma":0.0001849884,"threshold_uncertainty_score":0.99998283},"labels":[],"label_agreement":null},{"id":"W2092074155","doi":"10.1016/j.carpath.2004.03.483","title":"MICROARRAY PROFILING OF CHANGES IN THE EXPRESSION PATTERN OF TRANSCRIPTION FACTOR GENES IN OXIDIZED LOW-DENSITY LIPOPROTEIN ACTIVATED VASCULAR SMOOTH MUSCLE CELLS","year":2004,"lang":"en","type":"article","venue":"Cardiovascular Pathology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Gene silencing; Piwi-interacting RNA; RNA Helicase A; Transgene; RNA interference; Dicer; Cell biology; Small interfering RNA; Chromatin; RNA silencing; RNA; Chromatin remodeling; Genetics; Molecular biology; Gene; Helicase","score_opus":0.008721971451663778,"score_gpt":0.23074791214957524,"score_spread":0.22202594069791146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092074155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96244526,0.0055036806,0.031404052,0.000017715165,0.00011080844,0.0004893791,0.00001593338,0.0000068395434,0.0000063174843],"genre_scores_gemma":[0.9978914,0.00087855913,0.00103409,0.000021043867,0.000060356953,0.000050623352,0.00004044513,0.000022606757,8.507009e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986578,0.00026713556,0.00028411948,0.00036805146,0.00017833691,0.0002445287],"domain_scores_gemma":[0.9992437,0.000008994045,0.00006875548,0.0005931604,0.000058212685,0.000027207456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000535897,0.0001811478,0.0004134254,0.00011115455,0.000020779831,0.0000043323407,0.00020607574,0.00024876828,0.0000025160737],"category_scores_gemma":[0.000028805665,0.00015224595,0.00036626525,0.00015752901,0.0000741774,0.0000042744123,0.000046721532,0.00014109974,5.375356e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029045572,0.00008038236,0.00020416468,0.00014270237,0.00005620588,0.000024157172,0.00072095887,0.0061089834,0.9850893,5.163672e-7,5.336181e-7,0.0075430353],"study_design_scores_gemma":[0.0014976049,0.00010326923,0.017304705,0.000074046075,0.00003278848,0.000008263128,0.00032457802,0.000007972993,0.98034626,0.000008399591,0.00014270612,0.00014937985],"about_ca_topic_score_codex":0.00018788976,"about_ca_topic_score_gemma":0.0001786419,"teacher_disagreement_score":0.03544615,"about_ca_system_score_codex":0.00001765305,"about_ca_system_score_gemma":0.000029324246,"threshold_uncertainty_score":0.62084097},"labels":[],"label_agreement":null},{"id":"W2092201893","doi":"10.2135/cropsci2003.1590","title":"Transgenic Herbicide Tolerant Canola—The Canadian Experience","year":2003,"lang":"en","type":"article","venue":"Crop Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Monsanto (Canada); BC Research (Canada); Saskatchewan Health Authority; University of Alberta","funders":"","keywords":"Canola; Cultivar; Biology; Brassica; Rapeseed; Glyphosate; Agronomy; Glufosinate; Biotechnology","score_opus":0.010040343211598687,"score_gpt":0.2909791145485695,"score_spread":0.2809387713369708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092201893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98991996,0.00069090247,0.0032060489,0.00014142902,0.00029051144,0.00009271713,0.0000019852,0.0000061945666,0.00565028],"genre_scores_gemma":[0.9987804,0.00001587262,0.0003859452,0.00032752834,0.000035309735,0.000012226028,8.8018936e-7,0.0000066229595,0.00043518798],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912065,0.000012571946,0.00008783783,0.00026382206,0.00014782068,0.0003673128],"domain_scores_gemma":[0.9994111,0.000002992896,0.000011852141,0.0003372647,0.000051988693,0.0001847883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002357086,0.00008288542,0.00004874257,0.000034934077,0.00042062366,0.00006949286,0.0003716259,0.000037119145,0.000036853507],"category_scores_gemma":[0.00007727462,0.00006405184,0.000030940202,0.00025689992,0.0003848424,0.0000037381214,0.000017386134,0.000057529123,0.000010312217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000014654021,0.000004428848,0.0010608953,0.000002018119,0.0000021878677,0.0000021942706,0.00047563642,0.0012544045,0.9958566,0.00037099098,0.00015111336,0.00081810367],"study_design_scores_gemma":[0.00009130341,0.0000339696,0.005615192,0.0000037687346,0.0000027130939,0.000030321258,0.00018164807,0.00016749965,0.89574194,0.000018984569,0.09797159,0.00014105086],"about_ca_topic_score_codex":0.0071297404,"about_ca_topic_score_gemma":0.072796226,"teacher_disagreement_score":0.1001146,"about_ca_system_score_codex":0.000033593566,"about_ca_system_score_gemma":0.0005749706,"threshold_uncertainty_score":0.99948186},"labels":[],"label_agreement":null},{"id":"W2092610623","doi":"10.1016/s0012-1606(03)00097-6","title":"Parp1-deficiency induces differentiation of ES cells into trophoblast derivatives","year":2003,"lang":"en","type":"article","venue":"Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Trophoblast; Biology; Embryonic stem cell; Giant cell; Cellular differentiation; Cell biology; Molecular biology; Cell culture; PARP1; Phenotype; Stem cell; Poly ADP ribose polymerase; Genetics; Gene; Placenta; Polymerase; Fetus","score_opus":0.007237557359265992,"score_gpt":0.27167476976911253,"score_spread":0.2644372124098465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092610623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899034,0.00046609057,0.008707961,0.000008597376,0.0001796574,0.0000785528,0.0000056935774,0.0000068970216,0.0006431414],"genre_scores_gemma":[0.99289906,0.00012830574,0.006788761,0.000028311357,0.000019206229,0.000011517174,0.00006655537,0.000008910291,0.00004938757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993511,0.00003975784,0.00019300774,0.00021375783,0.000042220385,0.00016019195],"domain_scores_gemma":[0.99978495,0.000010220834,0.00005515231,0.00008691614,0.000029267654,0.000033513905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006406985,0.0001177955,0.00012013297,0.00004737705,0.000043413293,0.0000044177145,0.00009471681,0.00010462775,0.000037009606],"category_scores_gemma":[0.000041340038,0.000106707346,0.000036125966,0.00007770905,0.000076561206,0.0000019274028,0.0000494411,0.000038945498,0.0000061978576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008502835,0.00003537063,0.00790188,0.000012888255,0.000019954092,1.9672031e-7,0.00020881656,0.000014979335,0.9899256,0.00031681795,0.00004381796,0.0015111407],"study_design_scores_gemma":[0.00020710981,0.00012328582,0.014096541,0.000004721785,0.0000037737382,0.000004084896,0.00028250596,0.000002836156,0.98233926,0.00010626547,0.002699327,0.00013027086],"about_ca_topic_score_codex":0.0000075921257,"about_ca_topic_score_gemma":0.0000115604125,"teacher_disagreement_score":0.007586357,"about_ca_system_score_codex":0.000011027011,"about_ca_system_score_gemma":0.000045087672,"threshold_uncertainty_score":0.43513992},"labels":[],"label_agreement":null},{"id":"W2092975818","doi":"10.1083/jcb.1793rr4","title":"Localized mRNA is the norm","year":2007,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biology; Embryo; Cell biology; Computational biology; Evolutionary biology","score_opus":0.006194450826227133,"score_gpt":0.29720846143323154,"score_spread":0.2910140106070044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092975818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9493142,0.004733853,0.042123012,0.00060996413,0.00037474986,0.000059015223,0.000001941925,0.0000021183364,0.0027811439],"genre_scores_gemma":[0.9971616,0.00091937295,0.0003114046,0.0008114559,0.00043226106,2.6492594e-7,0.0000016013811,0.000007969961,0.0003540257],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941957,0.00005025114,0.00023502871,0.000058925154,0.000057133573,0.00017909784],"domain_scores_gemma":[0.9994973,0.0000588075,0.00012259519,0.00020178995,0.000076947894,0.00004257056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008916345,0.00008097224,0.0001004527,0.000023117416,0.000055274635,0.0000045686443,0.0003187889,0.00008755226,0.00003439903],"category_scores_gemma":[0.0000339619,0.000039448925,0.00009165815,0.000051160205,0.000094452655,8.536292e-7,0.00005767873,0.000143182,0.000007417596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012217938,0.000012706864,0.00022490429,0.0000028541251,0.000034019733,0.0000015883013,0.00011244065,0.0001215427,0.994752,0.000019835983,0.001588095,0.0030078474],"study_design_scores_gemma":[0.00030284678,0.0002601816,0.00055269984,0.0000023486843,0.000025568712,0.00008990918,0.000112743546,0.000020216929,0.81333125,0.00012292458,0.18512678,0.000052566742],"about_ca_topic_score_codex":0.0000068902573,"about_ca_topic_score_gemma":0.000010913766,"teacher_disagreement_score":0.18353868,"about_ca_system_score_codex":0.000005883538,"about_ca_system_score_gemma":0.000028619428,"threshold_uncertainty_score":0.16086805},"labels":[],"label_agreement":null},{"id":"W2095273007","doi":"10.1073/pnas.0610878104","title":"A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin","year":2007,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; City of Hope","keywords":"Nonsense mutation; Nonsense; In vivo; Stop codon; Biology; Nonsense-mediated decay; Medicine; Pharmacology; Genetics; Mutation; Bioinformatics; Missense mutation; Gene","score_opus":0.03347657071228902,"score_gpt":0.36052894222043846,"score_spread":0.3270523715081495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095273007","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99318606,0.00008292108,0.0057022525,0.0005772317,0.000009585793,0.0003546471,0.000019162042,0.0000044346416,0.00006372891],"genre_scores_gemma":[0.975359,0.0000103440625,0.023971282,0.00030654026,0.00004406453,0.000020306197,2.9923203e-7,0.0000064674705,0.00028164577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907035,0.00000413426,0.00023065525,0.00019111816,0.0003571975,0.00014654933],"domain_scores_gemma":[0.9995425,0.00006951512,0.0001171024,0.000011366979,0.00021976254,0.000039749677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016382342,0.000080371916,0.0000845646,0.0001037532,0.00008220381,0.000010665105,0.00028105173,0.000072478215,6.828767e-7],"category_scores_gemma":[0.00062234193,0.000059955357,0.00006295864,0.00019957618,0.0001298573,0.0000074543213,0.000049594346,0.000041269494,2.0028882e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025685513,0.000022981474,0.00015912272,0.000016640042,0.000009431083,1.756984e-9,0.00028505636,0.01605365,0.9823964,0.00019955529,0.00015859818,0.00044168415],"study_design_scores_gemma":[0.00029625927,0.00013227758,0.0041502835,0.000013878303,0.000004273841,0.000002243827,0.00012780064,0.036856085,0.95759326,0.0006482272,0.000101481586,0.00007395394],"about_ca_topic_score_codex":0.0000014593874,"about_ca_topic_score_gemma":4.581426e-7,"teacher_disagreement_score":0.024803188,"about_ca_system_score_codex":0.000011390735,"about_ca_system_score_gemma":0.000028768009,"threshold_uncertainty_score":0.24449085},"labels":[],"label_agreement":null},{"id":"W2095509362","doi":"10.1111/j.1399-3054.2006.00770.x","title":"Relationship between RNA splicing and exon editing near intron junctions in wheat mitochondria","year":2006,"lang":"en","type":"article","venue":"Physiologia Plantarum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Exon; Intron; RNA editing; RNA splicing; Biology; RNA; Exon trapping; Genetics; Group II intron; Gene","score_opus":0.010036940608391894,"score_gpt":0.26421296589371146,"score_spread":0.2541760252853196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095509362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973861,0.0002763254,0.001566916,0.000092485774,0.00018274193,0.000102799255,0.000021643453,0.00002000493,0.0003509972],"genre_scores_gemma":[0.9978539,0.000016082959,0.0008106786,0.000025699055,0.0007932354,0.000011470196,0.00038274156,0.000012528741,0.00009367092],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992804,0.000026806369,0.00016897795,0.0002495734,0.00004980761,0.00022441633],"domain_scores_gemma":[0.9997363,0.00004248017,0.000035106717,0.00014111398,0.000010715824,0.000034276138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007103646,0.00012187054,0.00012434734,0.00004081698,0.00009646666,0.000020695228,0.00006233395,0.000112841,0.0000030670817],"category_scores_gemma":[0.00004295195,0.00012007261,0.000030191784,0.00006953804,0.000037926304,0.000004922667,0.000055966368,0.00013794591,0.000005339897],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020760584,0.00001673752,0.34137338,0.000022495597,0.000007328902,0.0000015696294,0.0000285209,0.0027264962,0.6535127,0.000047139947,0.0019412462,0.00030157765],"study_design_scores_gemma":[0.00041245852,0.00009165589,0.93455106,0.000023582723,0.0000126353525,0.0000064841292,0.000059308215,0.00035636887,0.06273604,0.0003312372,0.0012423097,0.0001768393],"about_ca_topic_score_codex":0.00026544547,"about_ca_topic_score_gemma":0.00018986348,"teacher_disagreement_score":0.5931777,"about_ca_system_score_codex":0.000013302126,"about_ca_system_score_gemma":0.000013490281,"threshold_uncertainty_score":0.4896419},"labels":[],"label_agreement":null},{"id":"W2096790660","doi":"10.1093/bfgp/els005","title":"Not seeing the genomes for the DNA","year":2012,"lang":"en","type":"article","venue":"Briefings in Functional Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Canadian Institute for Advanced Research","funders":"","keywords":"Biology; Genome; Computational biology; Evolutionary biology; DNA; Genetics; Gene","score_opus":0.01710477178758591,"score_gpt":0.26300379481217373,"score_spread":0.24589902302458783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096790660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8015473,0.018021936,0.17242493,0.0045215567,0.001605257,0.0007123769,0.000039129813,0.000021923355,0.001105615],"genre_scores_gemma":[0.9946269,0.00026647962,0.0007812742,0.0023054515,0.0011637949,0.000073510644,0.000031336225,0.000022027561,0.0007292579],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994337,0.00000921423,0.00012628833,0.00013096197,0.00006568616,0.00023413719],"domain_scores_gemma":[0.9996479,0.00008094711,0.00003061202,0.00018474773,0.000026573847,0.000029211486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032030765,0.00009141951,0.000058692593,0.000015573658,0.00014306475,0.000020507416,0.00013049615,0.000058284648,0.000011559589],"category_scores_gemma":[0.000060896,0.00006306641,0.00007173973,0.000043268967,0.000039991948,0.0000026620062,0.000071583476,0.000070028975,0.0000054514285],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003045281,0.000084147665,0.008921928,0.000041127623,0.00021933649,4.140311e-7,0.0007873431,0.05151715,0.8734073,0.005857783,0.03008691,0.028772052],"study_design_scores_gemma":[0.00028380082,0.000024194676,0.03498366,0.000002302867,0.00001876674,0.000020949492,0.00011856146,0.0008431139,0.04672262,0.00007540379,0.91677743,0.00012921795],"about_ca_topic_score_codex":0.000015515647,"about_ca_topic_score_gemma":0.000015825834,"teacher_disagreement_score":0.8866905,"about_ca_system_score_codex":0.000021068307,"about_ca_system_score_gemma":0.000032475553,"threshold_uncertainty_score":0.25717735},"labels":[],"label_agreement":null},{"id":"W2097309207","doi":"10.1006/excr.2001.5443","title":"Evidence for Repeat-Induced Gene Silencing in Cultured Mammalian Cells: Inactivation of Tandem Repeats of Transfected Genes","year":2002,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Regional Cancer Foundation","funders":"","keywords":"Biology; Gene silencing; Trichostatin A; Transgene; Gene; Reporter gene; Transfection; Molecular biology; DNA methylation; Genetics; Histone; Gene expression; Histone deacetylase","score_opus":0.13384830002842607,"score_gpt":0.4205477769705366,"score_spread":0.2866994769421105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097309207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890859,0.009219811,0.00087911205,0.000013706457,0.00005403141,0.000433211,0.000005340573,0.0000043810746,0.00030447336],"genre_scores_gemma":[0.9974419,0.0005817255,0.001579015,0.000003537706,0.00006393981,0.00006972028,0.000015856764,0.000018837161,0.00022549479],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882656,0.00008389791,0.00028024975,0.00030554432,0.00024767374,0.00025609593],"domain_scores_gemma":[0.9994676,0.00004960606,0.00004342861,0.00026099128,0.0001255854,0.0000527823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036920083,0.00010597489,0.00014921733,0.000105758,0.000042568714,0.0000076130955,0.00015993346,0.00011790075,0.000032424057],"category_scores_gemma":[0.00006273371,0.00010794057,0.00007346127,0.00020516603,0.000045718367,0.00000716522,0.000049630562,0.00008964436,8.286492e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010784343,0.0001485667,0.0001903483,0.0000790237,0.000008374907,0.0000015480791,0.00095217634,0.00021287602,0.9971611,0.0000023188509,0.00008875889,0.0010470637],"study_design_scores_gemma":[0.000625791,0.00074550515,0.00033588024,0.00006015736,0.0000028287825,0.0000014869523,0.00095928635,0.00057730003,0.99651617,0.000002773572,0.000069453934,0.00010339261],"about_ca_topic_score_codex":0.0001301718,"about_ca_topic_score_gemma":0.000016264401,"teacher_disagreement_score":0.008638086,"about_ca_system_score_codex":0.000047689784,"about_ca_system_score_gemma":0.000025726313,"threshold_uncertainty_score":0.44016886},"labels":[],"label_agreement":null},{"id":"W2097316182","doi":"10.1534/g3.112.002238","title":"Oligoarray Comparative Genomic Hybridization-Mediated Mapping of Suppressor Mutations Generated in a Deletion-Biased Mutagenesis Screen","year":2012,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Space Agency","keywords":"Biology; Genetics; Suppressor; Mutagenesis; Gene; Gene duplication; Comparative genomic hybridization; Suppressor mutation; Genetic screen; Mutation; Caenorhabditis elegans; Mutant; Synthetic lethality; Genome","score_opus":0.02187721642669752,"score_gpt":0.2916234743864892,"score_spread":0.2697462579597917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097316182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8040337,0.16947472,0.025371686,0.000023614475,0.00021547207,0.0004677043,0.00020022862,0.000024549963,0.00018832796],"genre_scores_gemma":[0.9759301,0.011634393,0.010428994,0.0000624438,0.00029056202,0.00007443669,0.0014009041,0.00006406384,0.00011409678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99789196,0.00013229747,0.00070425734,0.0004334229,0.00021917056,0.0006188979],"domain_scores_gemma":[0.99880797,0.000049977636,0.00020674459,0.0005114977,0.00021641873,0.00020738451],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002250801,0.00035404126,0.00040389498,0.00029920368,0.00009934207,0.000024763518,0.0003072461,0.0002035873,0.00006389454],"category_scores_gemma":[0.000017969163,0.00040247486,0.00013259833,0.00051076815,0.00011742295,0.000010261438,0.00013715719,0.00009956878,0.000023909344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002615955,0.00011613674,0.04103846,0.000044510904,0.00012434501,0.0000017813578,0.0008662506,0.067717195,0.87733585,0.000009315881,0.00008407189,0.012635932],"study_design_scores_gemma":[0.0014040483,0.00014014084,0.045074172,0.00003286741,0.00007913738,0.00002032538,0.0008881512,0.008872615,0.91686904,0.000009668041,0.02591777,0.00069205975],"about_ca_topic_score_codex":0.00004672352,"about_ca_topic_score_gemma":0.00009556022,"teacher_disagreement_score":0.17189641,"about_ca_system_score_codex":0.000048698825,"about_ca_system_score_gemma":0.00013607064,"threshold_uncertainty_score":0.9998427},"labels":[],"label_agreement":null},{"id":"W2098449208","doi":"10.1186/1472-6939-15-58","title":"Ocular gene transfer in the spotlight: implications of newspaper content for clinical communications","year":2014,"lang":"en","type":"article","venue":"BMC Medical Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Provincial Laboratory of Public Health; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Newspaper; Framing (construction); Timeline; Psychological intervention; Clinical trial; Philosophy of medicine; Medicine; Public relations; Political science; Alternative medicine; Law; History; Pathology","score_opus":0.15810661345598873,"score_gpt":0.4569592136688305,"score_spread":0.29885260021284177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098449208","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14966922,0.0014153568,0.8355147,0.01251987,0.00011050961,0.00035974887,0.000018138455,0.0000072967596,0.00038510704],"genre_scores_gemma":[0.98610306,0.0033639972,0.0077189254,0.0024457718,0.00016037868,0.000081960716,0.00008733985,0.000011678052,0.00002689354],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988508,0.00029444092,0.00037909337,0.00015606814,0.00019268156,0.00012690393],"domain_scores_gemma":[0.9972465,0.001826303,0.000024804307,0.00072511507,0.00010109299,0.00007617385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027147203,0.00007259346,0.00013409524,0.000015688225,0.000053239768,0.0000049969217,0.00054820627,0.00036667124,0.000007131493],"category_scores_gemma":[0.005307549,0.00005272592,0.0001293893,0.000055571887,0.00023096206,9.367218e-7,0.000056603094,0.00033032993,0.0000012650484],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004699816,0.0033482746,0.13924555,0.00213641,0.00048199756,0.0000020021948,0.0058726585,0.0010893969,0.42710924,0.36519256,0.010341166,0.044710744],"study_design_scores_gemma":[0.0073668663,0.0013332289,0.2748981,0.00034609108,0.0002558206,0.000053386684,0.0011226633,0.006675672,0.07187688,0.0037873888,0.6314171,0.00086680334],"about_ca_topic_score_codex":0.000018962366,"about_ca_topic_score_gemma":0.0022345649,"teacher_disagreement_score":0.8364338,"about_ca_system_score_codex":0.0000027818835,"about_ca_system_score_gemma":0.00032856685,"threshold_uncertainty_score":0.63540155},"labels":[],"label_agreement":null},{"id":"W2098756183","doi":"10.1534/genetics.109.109686","title":"A<i>Caenorhabditis elegans</i>RNA-Directed RNA Polymerase in Sperm Development and Endogenous RNA Interference","year":2009,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Biology; RNA interference; Small interfering RNA; Gene silencing; Caenorhabditis elegans; Piwi-interacting RNA; RNA; Genetics; Cell biology; Small RNA; Trans-acting siRNA; Gene; RNA silencing; RNA-induced silencing complex","score_opus":0.010792926302673266,"score_gpt":0.25057109081303686,"score_spread":0.2397781645103636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098756183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98634154,0.007319652,0.004591532,0.000078142526,0.00013384383,0.00016129576,0.000011198955,0.00003158722,0.0013312172],"genre_scores_gemma":[0.9912159,0.0010487853,0.0069952537,0.00025326808,0.00014937768,0.000009301249,0.000050551873,0.000023567845,0.00025398843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987915,0.000024888062,0.00029215854,0.00038790147,0.000115276416,0.00038826943],"domain_scores_gemma":[0.9994825,0.000008047598,0.000043400938,0.00028530243,0.000041293235,0.00013946024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008171094,0.00023265474,0.00017978733,0.000082219274,0.000056218425,0.000034524153,0.0001809009,0.00013414465,0.00001589086],"category_scores_gemma":[0.0000230622,0.00025366523,0.000036719863,0.00012261608,0.000038015958,0.0000026281448,0.00008215134,0.00011958981,0.0000057788307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022665286,0.00005103774,0.00042904483,0.00001220919,0.000018009556,0.000029863806,0.00030982692,0.00018269377,0.9077937,0.000008971331,0.00018210575,0.090959884],"study_design_scores_gemma":[0.00054136687,0.00022931074,0.007908013,0.000026597789,0.000010829547,0.000065584034,0.000052573952,0.00016967671,0.9797597,0.000016316704,0.01088901,0.0003310204],"about_ca_topic_score_codex":0.000016856548,"about_ca_topic_score_gemma":0.00017605578,"teacher_disagreement_score":0.09062886,"about_ca_system_score_codex":0.00002223786,"about_ca_system_score_gemma":0.00007872224,"threshold_uncertainty_score":0.99999154},"labels":[],"label_agreement":null},{"id":"W2099538751","doi":"10.1038/mt.2013.111","title":"Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Transcription activator-like effector nuclease; Genome editing; Dystrophin; Biology; Duchenne muscular dystrophy; Genetics; CRISPR; Exon; Gene; Computational biology","score_opus":0.002392924651279668,"score_gpt":0.2134090732554655,"score_spread":0.21101614860418583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099538751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97250116,0.0017421788,0.024686217,0.00003017811,0.00057151093,0.0003733889,0.000024211435,0.0000288691,0.00004227766],"genre_scores_gemma":[0.99643683,0.00025003898,0.0021408352,0.0001375468,0.00022623851,0.00008228678,0.0005915012,0.00006328381,0.000071451825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998572,0.00009088366,0.00028571623,0.00049607793,0.00019978851,0.00035554354],"domain_scores_gemma":[0.99932504,0.000008436235,0.00008927336,0.00039258882,0.000079439036,0.00010525441],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007854398,0.00025718333,0.00019472437,0.00007794491,0.00006411053,0.000054687942,0.00019963195,0.00022304755,0.00006610035],"category_scores_gemma":[0.000038500137,0.00025680967,0.00009980881,0.00011685566,0.00002969164,0.000011476605,0.00006199425,0.00018341179,0.000020767164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033538876,0.00007740777,0.0012889621,0.000004328203,0.000030078483,0.0000046522177,0.00009286734,0.0020998642,0.9934935,4.3698373e-7,0.00097035116,0.0019040251],"study_design_scores_gemma":[0.000986032,0.00019476251,0.010179237,0.000028601526,0.00000509517,7.3243257e-7,0.0000525055,0.0005013665,0.98034185,0.000029434534,0.0073951646,0.00028519938],"about_ca_topic_score_codex":0.00034101127,"about_ca_topic_score_gemma":0.000003852624,"teacher_disagreement_score":0.02393565,"about_ca_system_score_codex":0.000039485756,"about_ca_system_score_gemma":0.000012556713,"threshold_uncertainty_score":0.99998844},"labels":[],"label_agreement":null},{"id":"W2099827637","doi":"10.1186/1754-1611-8-28","title":"The case for decoupling assembly and submission standards to maintain a more flexible registry of biological parts","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Texas at Austin; University of Ottawa; North Carolina Agricultural and Technical State University; National Science Foundation","keywords":"Computer science; Decoupling (probability); Sequence (biology); Computational biology; Biology; Genetics; Engineering; Control engineering","score_opus":0.014890704561989342,"score_gpt":0.32334915202888365,"score_spread":0.3084584474668943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099827637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70155305,0.00090056885,0.29719806,0.00014319252,0.000099906705,0.00008307427,0.000009312043,0.000005341585,0.0000075072376],"genre_scores_gemma":[0.98826456,0.00028299415,0.011179069,0.000034540866,0.00021039433,0.000006575796,0.0000028002564,0.000010120254,0.000008940456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991768,0.000019600431,0.00034597376,0.00014903216,0.00008563024,0.00022298927],"domain_scores_gemma":[0.99929714,0.00015496694,0.00010861494,0.00014381882,0.00014728052,0.00014819451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010541799,0.00012953395,0.00021846007,0.00003673087,0.00006726699,0.000022437973,0.00014321123,0.00014782621,0.000001171172],"category_scores_gemma":[0.0012760377,0.000076945595,0.000108092245,0.000057975016,0.0000397452,0.0000027426947,0.00007953973,0.00010851765,6.296428e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033659727,0.000027018858,0.0009168625,0.000055017368,0.00007438642,0.000036135523,0.000030962867,0.03755207,0.9485094,0.00048237297,0.0002880141,0.011691158],"study_design_scores_gemma":[0.0018211986,0.005446803,0.0060816677,0.00023304166,0.00006168957,0.0031339272,0.0005422358,0.030180681,0.842043,0.00035045308,0.10949029,0.00061501615],"about_ca_topic_score_codex":0.0000013808454,"about_ca_topic_score_gemma":0.0000011435543,"teacher_disagreement_score":0.2867115,"about_ca_system_score_codex":0.000015383257,"about_ca_system_score_gemma":0.00002377122,"threshold_uncertainty_score":0.313775},"labels":[],"label_agreement":null},{"id":"W2099968189","doi":"10.1128/mbio.00896-14","title":"A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa","year":2014,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":280,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Gene; Biology; Pseudomonas aeruginosa; Genetics; Genome; Mobile genetic elements; CRISPR interference; Bacteriophage; Computational biology; Escherichia coli; Genome editing; Bacteria","score_opus":0.006637715501293056,"score_gpt":0.25940440393131026,"score_spread":0.2527666884300172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099968189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94006616,0.0043272907,0.054122552,0.000064893364,0.00035360167,0.00016742633,0.000010344546,0.000016926286,0.00087079447],"genre_scores_gemma":[0.9982047,0.00013519594,0.0011360296,0.000035684992,0.00025562083,0.0000035629469,0.000020069809,0.00002112815,0.00018799605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916434,0.000042734682,0.0002593618,0.00021579025,0.00013018351,0.0001876094],"domain_scores_gemma":[0.9993105,0.000017493456,0.00009309304,0.0004417298,0.00007545354,0.00006172668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019162243,0.00014442857,0.00020847871,0.000033559445,0.000034856464,0.000009317015,0.00022260475,0.00010973877,0.000011084727],"category_scores_gemma":[0.00003919677,0.000111462956,0.00009900527,0.00011835042,0.000047718197,0.0000021301594,0.00010193654,0.00006008967,0.0000075811517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023487646,0.000023122955,0.0016315602,0.00013824193,0.00004714001,9.162045e-7,0.00010934592,0.00020325162,0.9924086,0.0004186562,0.0017874286,0.0032082642],"study_design_scores_gemma":[0.00039668253,0.00020047835,0.0038095783,0.000042243988,0.000039097085,0.000019944477,0.00014038103,0.00024218732,0.9830931,0.000011969817,0.011873586,0.00013074042],"about_ca_topic_score_codex":0.00015135993,"about_ca_topic_score_gemma":0.000026260532,"teacher_disagreement_score":0.058138542,"about_ca_system_score_codex":0.0000058670043,"about_ca_system_score_gemma":0.000030313287,"threshold_uncertainty_score":0.45453274},"labels":[],"label_agreement":null},{"id":"W2100525241","doi":"10.1158/0008-5472.can-09-1178","title":"Functional Restoration of BRCA2 Protein by Secondary <i>BRCA2</i> Mutations in <i>BRCA2</i> -Mutated Ovarian Carcinoma","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":326,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute; Searle Scholars Program; National Institutes of Health; Pfizer","keywords":"Cisplatin; Ovarian cancer; BRCA2 Protein; Cancer research; Ovarian carcinoma; Mutation; Biology; Cancer; Medicine; Chemotherapy; Genetics; Germline mutation; Gene","score_opus":0.022712221383821406,"score_gpt":0.35096565398464996,"score_spread":0.32825343260082857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2100525241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929131,0.0027606338,0.0018608978,0.0007582999,0.00007782793,0.00043362105,0.000079524514,0.0000106337975,0.001105431],"genre_scores_gemma":[0.99795514,0.00007333595,0.00018102955,0.00007793852,0.0001512379,0.00012753658,0.0003543104,0.000017671706,0.0010617711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868184,0.000102290935,0.00025534572,0.0003342078,0.0003006671,0.00032562797],"domain_scores_gemma":[0.99934924,0.000015308056,0.00003994621,0.0002703836,0.0002369497,0.000088193905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004061722,0.00011618703,0.00012781304,0.0001429827,0.00008077682,0.000022550765,0.00015558979,0.0001349741,0.00009552756],"category_scores_gemma":[0.00007315226,0.00012649928,0.000044491087,0.00041043165,0.00008909078,0.0000094237075,0.000041852654,0.00028098837,0.000005469708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001293341,0.000063010906,0.000673125,0.00003077968,0.000013575991,0.000003755298,0.000089113215,0.0010516162,0.98425806,0.000085370644,0.009911538,0.0036907077],"study_design_scores_gemma":[0.0009638352,0.00031917563,0.020229463,0.00003376387,0.0000044775275,0.0000045106012,0.00009925207,0.00014403486,0.9677838,0.00022974108,0.010034406,0.00015352905],"about_ca_topic_score_codex":0.00030612206,"about_ca_topic_score_gemma":0.00023787402,"teacher_disagreement_score":0.019556338,"about_ca_system_score_codex":0.00007506479,"about_ca_system_score_gemma":0.00039857454,"threshold_uncertainty_score":0.51584905},"labels":[],"label_agreement":null},{"id":"W2101091609","doi":"10.1136/jfprhc-2013-100738","title":"Welcome Prince George, but if only…","year":2013,"lang":"en","type":"article","venue":"Journal of Family Planning and Reproductive Health Care","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Context (archaeology); Computational biology; CRISPR; Function (biology); Biology; Flexibility (engineering); Genetics; Mutation; Genome; Drug development; Gene; Drug","score_opus":0.013694903100550253,"score_gpt":0.32607290034954445,"score_spread":0.3123779972489942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101091609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9538293,0.042755894,0.0014929575,0.0008285,0.0006130124,0.0001370919,0.00000584535,0.0000063622765,0.0003310689],"genre_scores_gemma":[0.99467295,0.0007497562,0.002550954,0.0003694659,0.001202723,0.0000029669231,0.000008884028,0.000016375434,0.00042590575],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99906254,0.000041185318,0.0003036346,0.0002496061,0.00012830153,0.00021471159],"domain_scores_gemma":[0.9991706,0.0000100441575,0.00018995318,0.00020744259,0.00027141703,0.00015053105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024616258,0.00012001082,0.00020458597,0.00006398761,0.00009534046,0.00002119542,0.0000914321,0.000069362,0.0000019515926],"category_scores_gemma":[0.00008706377,0.0000985556,0.000056340206,0.000052385774,0.00003858211,0.0000074343257,0.000047663394,0.00019486524,0.0000018548604],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047338428,0.00019697414,0.16191326,0.001213528,0.00051466504,0.00008340025,0.012994122,0.00937406,0.6082336,0.000070775735,0.08748566,0.11744657],"study_design_scores_gemma":[0.0010912134,0.0018635539,0.7905918,0.00031035935,0.000028027114,0.00090493535,0.015131636,0.000026975458,0.0273485,0.00004561518,0.16222909,0.00042829962],"about_ca_topic_score_codex":0.00003722248,"about_ca_topic_score_gemma":8.724985e-7,"teacher_disagreement_score":0.62867856,"about_ca_system_score_codex":0.000023939368,"about_ca_system_score_gemma":0.00015773272,"threshold_uncertainty_score":0.4018981},"labels":[],"label_agreement":null},{"id":"W2101093449","doi":"10.1534/genetics.166.4.1833","title":"Molecular and Functional Analysis of scalloped Recessive Lethal Alleles in Drosophila melanogaster","year":2004,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; Drosophila melanogaster; Allele; Genetics; Phenotype; Gene; Mutant; Null allele; Drosophilidae","score_opus":0.007546592334972162,"score_gpt":0.2649341145404539,"score_spread":0.2573875222054817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101093449","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98096097,0.002183224,0.016481258,0.000094636875,0.000037699254,0.000064564185,0.000011797307,0.0000031264917,0.00016274907],"genre_scores_gemma":[0.9969165,0.00021931132,0.0026608978,0.000057340705,0.00003558559,0.0000059039235,0.00007222237,0.000011490351,0.000020767067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999337,0.000015534122,0.00017992021,0.00022441508,0.000103512204,0.00013960175],"domain_scores_gemma":[0.99968547,0.0000050960084,0.00003807568,0.00017907498,0.000043894517,0.000048412938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006610887,0.00010544913,0.0001552772,0.00012701667,0.00001437596,0.0000075519574,0.000063669184,0.00009862339,0.000008586472],"category_scores_gemma":[0.000017055141,0.00011026182,0.00006811113,0.0002093751,0.000051882307,0.0000011825706,0.000069488706,0.000049416696,6.731719e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023582648,0.000031140004,0.010390523,0.000011222573,0.00022693357,0.0000064353276,0.000080953076,0.18481341,0.80381244,0.00007394182,0.000010905258,0.00051851355],"study_design_scores_gemma":[0.001043862,0.00017733006,0.16539778,0.0000139940275,0.00024470864,0.0000120680215,0.000080827034,0.0008477505,0.830976,0.00023186687,0.0007351993,0.00023858852],"about_ca_topic_score_codex":0.000009737287,"about_ca_topic_score_gemma":0.00013396656,"teacher_disagreement_score":0.18396565,"about_ca_system_score_codex":0.0000072158773,"about_ca_system_score_gemma":0.000028110204,"threshold_uncertainty_score":0.44963464},"labels":[],"label_agreement":null},{"id":"W2101921189","doi":"10.1534/genetics.106.065508","title":"Low Impact of Germline Transposition on the Rate of Mildly Deleterious Mutation in <i>Caenorhabditis elegans</i>","year":2006,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Caenorhabditis elegans; Transposition (logic); Germline; Genetics; Mutation Accumulation; Mutation rate; Germline mutation; Mutation; Transposable element; Fecundity; Genome; Gene; Population","score_opus":0.003292705084167537,"score_gpt":0.2565918104506045,"score_spread":0.25329910536643696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101921189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918512,0.00050995033,0.007250376,0.000056674096,0.00003791936,0.0001439788,0.000071964976,0.0000031678078,0.00007478079],"genre_scores_gemma":[0.99916375,0.00015504753,0.00039643593,0.00004365764,0.000074857024,0.0000073008496,0.00012528847,0.000015463911,0.000018175653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993806,0.000036542293,0.0002473824,0.00013136308,0.00006858877,0.00013551273],"domain_scores_gemma":[0.9996526,0.00001640374,0.00006589437,0.00019681088,0.000050263898,0.000018003142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009486569,0.00010568396,0.00011213481,0.000042750482,0.000014596487,0.0000044254466,0.00008967623,0.00007658906,0.000007277577],"category_scores_gemma":[0.000009084159,0.00008641673,0.00009441506,0.00009811348,0.000039600993,0.0000010801078,0.00000936858,0.000048017988,7.5483933e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045855097,0.00005827474,0.0011478292,0.000020937965,0.000014753507,0.0000021891035,0.00004072923,0.08499469,0.9121891,0.000015700432,0.00015119913,0.0013187345],"study_design_scores_gemma":[0.00038626636,0.00050724094,0.066833764,0.000023431689,0.000012113706,0.000006826561,0.0000100848965,0.00089059357,0.9310518,0.00008358412,0.0001060009,0.000088270455],"about_ca_topic_score_codex":0.00009250677,"about_ca_topic_score_gemma":0.0001609613,"teacher_disagreement_score":0.08410409,"about_ca_system_score_codex":0.000010100191,"about_ca_system_score_gemma":0.000028338984,"threshold_uncertainty_score":0.3523972},"labels":[],"label_agreement":null},{"id":"W2101983500","doi":"10.1111/j.1365-2958.2010.07465.x","title":"A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Harvard University","keywords":"CRISPR; Biology; Nuclease; Genetics; DNA; RecBCD; Plasmid; Palindrome; Cas9; Mutagenesis; Holliday junction; Trans-activating crRNA; DNA repair; Genome; Computational biology; Mutation; Gene","score_opus":0.002907327633087618,"score_gpt":0.22431264777406001,"score_spread":0.2214053201409724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101983500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759597,0.0003558934,0.0010889348,0.000021819687,0.0006124943,0.00015640026,0.00002158398,0.000012497367,0.00013442086],"genre_scores_gemma":[0.9995848,0.000010310839,0.00021748233,0.000042909,0.00006286688,0.000007969863,0.00003961964,0.00001382572,0.000020204627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928474,0.00009643104,0.00019663043,0.00022556412,0.00002388183,0.00017272671],"domain_scores_gemma":[0.99951583,0.000008054417,0.00005532023,0.00036300858,0.000033830325,0.000023929419],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018524165,0.0001219491,0.0001497626,0.0000391497,0.000036092428,0.000005549329,0.00010507632,0.00022000096,0.000006738709],"category_scores_gemma":[0.00004733924,0.0001005318,0.000084905805,0.00006955406,0.000119744924,0.0000014972825,0.00017346724,0.00016374484,0.0000015944075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057789384,0.000021143054,0.0016080305,0.00002921523,0.000029797928,0.0000036760812,0.000034145607,0.000013449978,0.9978247,0.00011730294,0.00006349339,0.00019724466],"study_design_scores_gemma":[0.00045476927,0.00009859988,0.019665048,0.000011626662,0.000018803992,0.00012674685,0.00004197655,0.000015156818,0.9731579,0.0000057647053,0.006295012,0.00010859644],"about_ca_topic_score_codex":0.000056229834,"about_ca_topic_score_gemma":0.0001836126,"teacher_disagreement_score":0.024666812,"about_ca_system_score_codex":0.000006266725,"about_ca_system_score_gemma":0.000028119377,"threshold_uncertainty_score":0.40995678},"labels":[],"label_agreement":null},{"id":"W2102885629","doi":"10.1074/jbc.m202737200","title":"Xenopus Ribosomal RNA Gene Intergenic Spacer Elements Conferring Transcriptional Enhancement and Nucleolar Dominance-like Competition in Oocytes","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Directorate for Biological Sciences; Université Laval","keywords":"Xenopus; Ribosomal RNA; Biology; Gene; Nucleolus; Dominance (genetics); RNA; Intergenic region; Cell biology; Genetics; Genome","score_opus":0.014437692718474887,"score_gpt":0.25768382020951563,"score_spread":0.24324612749104074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102885629","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99234015,0.0050110505,0.002131802,0.00008624241,0.00011623531,0.000051060266,0.000006881507,0.000003005594,0.00025355228],"genre_scores_gemma":[0.99530077,0.0028561298,0.001412628,0.000062856234,0.00023152397,0.000003998791,0.000016500531,0.000007586353,0.00010798578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990727,0.000020019424,0.00042016248,0.00018443048,0.000108551045,0.00019414294],"domain_scores_gemma":[0.99963814,0.000008923488,0.00013061089,0.00008515225,0.00005131186,0.0000858561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016007466,0.00014150256,0.00019209403,0.000023517354,0.000029741237,0.000015434014,0.000105314546,0.00014124141,0.0002894896],"category_scores_gemma":[0.000033924956,0.0001196806,0.0000907654,0.000039419483,0.00006136607,0.0000053765043,0.00004613995,0.00016687637,0.0000016798857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088458,0.00009694843,0.0036174555,0.000024079527,0.00003640845,0.000014789585,0.000030999065,0.00005785796,0.9950942,0.0000048239685,0.00007006059,0.00086395635],"study_design_scores_gemma":[0.0011158421,0.00026015975,0.005899777,0.000049801693,0.000012069363,0.00013117322,0.000064215965,0.00019873476,0.98573214,0.000024347724,0.006357651,0.00015409307],"about_ca_topic_score_codex":0.0000010413819,"about_ca_topic_score_gemma":0.0000012067983,"teacher_disagreement_score":0.009362029,"about_ca_system_score_codex":0.00002873211,"about_ca_system_score_gemma":0.000009844726,"threshold_uncertainty_score":0.4880433},"labels":[],"label_agreement":null},{"id":"W2103924961","doi":"10.1038/ng1115","title":"Tailoring the genome: the power of genetic approaches","year":2003,"lang":"en","type":"review","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Biology; Caenorhabditis elegans; Drosophila melanogaster; Genome; Model organism; Inheritance (genetic algorithm); Genetics; Saccharomyces cerevisiae; Drosophila (subgenus); Computational biology; Genetic model; Caenorhabditis; Evolutionary biology; Gene","score_opus":0.022550006843635076,"score_gpt":0.3049980617698931,"score_spread":0.282448054926258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103924961","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002982365,0.99599713,0.0011650813,0.000020395993,0.00061553775,0.0007438987,0.000046979127,0.000008250725,0.0011044779],"genre_scores_gemma":[0.0042065764,0.9931598,0.0012951038,0.000081624756,0.0005037363,0.0000801898,0.00007637975,0.00010794237,0.00048867235],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980908,0.00015054956,0.0005558529,0.00051433465,0.00029183712,0.0003965928],"domain_scores_gemma":[0.9980818,0.0000464059,0.000269143,0.0014538101,0.00007948371,0.000069343114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032538766,0.00050415576,0.00064648996,0.000060625312,0.00011844086,0.00003729693,0.0010524835,0.000988855,0.00001849279],"category_scores_gemma":[0.000065989145,0.00028468439,0.00054430414,0.00029116875,0.00016966603,8.1432387e-7,0.0002760946,0.000888807,0.000008157344],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001526144,0.00012694072,0.00008749277,0.006996315,0.0016863805,0.000009660652,0.00031362227,0.002555097,0.00070848526,0.00023010807,0.004274899,0.98299575],"study_design_scores_gemma":[0.00008385664,0.00007630406,0.00008994255,0.00019016009,0.00044489032,0.00007745962,0.000045821118,0.000006659132,0.00048593784,0.000016794043,0.9981485,0.00033369538],"about_ca_topic_score_codex":8.7711095e-7,"about_ca_topic_score_gemma":0.0000043348277,"teacher_disagreement_score":0.9938736,"about_ca_system_score_codex":0.000018706518,"about_ca_system_score_gemma":0.00018769923,"threshold_uncertainty_score":0.99996054},"labels":[],"label_agreement":null},{"id":"W2106000733","doi":"10.1007/978-1-59259-732-1_16","title":"Stem Cells As Common Ancestors","year":2004,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Genealogy; History; Evolutionary biology; Biology","score_opus":0.0315355278662298,"score_gpt":0.2894186515775232,"score_spread":0.2578831237112934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106000733","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014656241,0.017026687,0.00026841875,0.0000032069743,0.0005025246,0.00034577865,0.000041059073,0.00005115082,0.98029554],"genre_scores_gemma":[0.09930809,0.0015997885,0.000103507184,0.00013472569,0.00071991497,0.000027298478,0.00008263528,0.00015481678,0.8978692],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99886113,0.000007988857,0.00025191263,0.00046015624,0.00016957454,0.00024922244],"domain_scores_gemma":[0.9991152,0.000004926245,0.0001076551,0.0006277648,0.000038850936,0.00010556552],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000050649807,0.0003653031,0.00027904328,0.000044655953,0.00006878065,0.000033768694,0.00030398593,0.00041574563,0.000052738003],"category_scores_gemma":[6.9119335e-7,0.0003949926,0.00017520164,0.0000018645391,0.00008718164,9.036692e-7,0.00017043349,0.00022476823,0.000031085852],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031453482,0.00010661283,0.0000046120667,0.0017259879,0.0018204456,0.00043646625,0.0010699598,0.0068295747,0.1735558,0.44909042,0.03411201,0.33093357],"study_design_scores_gemma":[0.00026427303,0.00015065985,0.0000017479707,0.000102755745,0.00006100587,0.000009538338,0.0000037305626,0.000003089657,0.2019154,0.0009810432,0.7960811,0.00042566276],"about_ca_topic_score_codex":0.000060598573,"about_ca_topic_score_gemma":0.000059681777,"teacher_disagreement_score":0.7619691,"about_ca_system_score_codex":0.000026898251,"about_ca_system_score_gemma":0.0000525765,"threshold_uncertainty_score":0.9998502},"labels":[],"label_agreement":null},{"id":"W2106404376","doi":"10.1016/j.cell.2013.04.055","title":"The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation","year":2013,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":416,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; SickKids Foundation; University of Toronto; University of British Columbia; Hospital for Sick Children; McGill University Health Centre; University of British Columbia Hospital","funders":"National Cancer Institute; Canadian Cancer Society Research Institute; Brain Tumour Charity; Wellcome Trust; McGill University","keywords":"Biology; Elongation; Translation (biology); Elongation factor; Blocking (statistics); Cell biology; Kinase; Genetics; Gene; Messenger RNA; RNA","score_opus":0.005144123763847668,"score_gpt":0.23678922663821214,"score_spread":0.23164510287436446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106404376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8795524,0.0013045926,0.11682499,0.0007025125,0.00010285646,0.00029233922,0.0000028872564,0.000011154379,0.0012062239],"genre_scores_gemma":[0.9979174,0.000104075974,0.0008320159,0.000094134426,0.00005854831,0.00003999245,0.000054334672,0.000009472785,0.00088998384],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995672,0.000013086506,0.000100191355,0.00013660181,0.00006673794,0.00011615149],"domain_scores_gemma":[0.9997232,0.000010877388,0.000022719236,0.00015541408,0.000046510067,0.000041255116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006852878,0.00006282775,0.000034527027,0.00001113788,0.00008442225,0.000034224067,0.000071482995,0.000044455326,0.000006709481],"category_scores_gemma":[0.000017013384,0.000054588127,0.000022112004,0.000049139082,0.000011244424,0.0000023158948,0.000011489816,0.00003107721,0.000014811565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008665753,0.0000076279307,0.000086847045,0.000006763317,0.0000029153207,6.006417e-8,0.00006593432,0.00037186692,0.98991966,0.000025291374,0.006157668,0.003346694],"study_design_scores_gemma":[0.00015567984,0.000023592045,0.0007377813,0.0000046528094,0.000003271604,1.5761061e-7,0.000052959753,0.00026362448,0.8831381,0.00006373402,0.115483515,0.00007288448],"about_ca_topic_score_codex":0.000008103556,"about_ca_topic_score_gemma":0.000023394377,"teacher_disagreement_score":0.118365005,"about_ca_system_score_codex":0.000008680699,"about_ca_system_score_gemma":0.000011112063,"threshold_uncertainty_score":0.22260392},"labels":[],"label_agreement":null},{"id":"W2106905614","doi":"10.1136/bmj.a1020","title":"Qualitative research methodologies: ethnography","year":2008,"lang":"en","type":"article","venue":"BMJ","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":776,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; The Wilson Centre; University of Toronto","funders":"","keywords":"Chromatin; Biology; Transcription (linguistics); Transcription factor; Genome; Computational biology; Gene; SOX2; Regulation of gene expression; DNA binding site; CRISPR; Genetics; Gene expression; Promoter","score_opus":0.3339254137224306,"score_gpt":0.5944646150799956,"score_spread":0.260539201357565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106905614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9044654,0.0026865443,0.07742692,0.0009280647,0.00022918069,0.00030934712,0.000009464721,0.000044828666,0.013900274],"genre_scores_gemma":[0.95263326,0.00035223825,0.044768073,0.000100981815,0.00032572824,0.000055174864,0.000019588917,0.000015595215,0.0017293632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989709,0.0003303201,0.00012412097,0.00020047335,0.00015161755,0.00022256566],"domain_scores_gemma":[0.9994414,0.000115162715,0.000017226317,0.00027616334,0.00010156273,0.00004850884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014900932,0.000070653805,0.00008179367,0.00006936732,0.00009915336,0.0000048574934,0.00013499735,0.00009360634,0.000014849957],"category_scores_gemma":[0.0006731351,0.00006545742,0.000065839435,0.0001704961,0.00015450554,9.604746e-7,0.000086806715,0.00011567758,0.00001976741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092578906,0.000038726455,0.00087181735,0.00002881115,0.00010475468,0.000021617805,0.0089790905,0.0003935134,0.77084374,0.00030403008,0.21490648,0.0034148481],"study_design_scores_gemma":[0.00052358117,0.00051936234,0.007087877,0.000014955045,0.000007081062,0.000073203395,0.009766349,0.000040018444,0.7584196,0.0011337083,0.22205375,0.0003605422],"about_ca_topic_score_codex":0.000018957719,"about_ca_topic_score_gemma":0.0000064743526,"teacher_disagreement_score":0.048167877,"about_ca_system_score_codex":0.000003896287,"about_ca_system_score_gemma":0.000035426237,"threshold_uncertainty_score":0.26692763},"labels":[],"label_agreement":null},{"id":"W2107594265","doi":"10.1111/j.1472-765x.2008.02531.x","title":"Mg<sup>2+</sup>-free buffer elevates transformation efficiency of<i>Vibrio parahaemolyticus</i>by electroporation","year":2009,"lang":"en","type":"article","venue":"Letters in Applied Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Canadian Institute for Public Safety Research and Treatment","funders":"","keywords":"Electroporation; Vibrio parahaemolyticus; Transformation efficiency; Nuclease; Transformation (genetics); Extracellular; Biology; Sucrose; Microbiology; Vibrio; Plasmid; DNA; Chemistry; Bacteria; Biochemistry; Gene; Agrobacterium; Genetics","score_opus":0.0023834103250075277,"score_gpt":0.21690516886103223,"score_spread":0.2145217585360247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107594265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92609483,0.00039969213,0.07190255,0.0008168147,0.000030336521,0.0002997999,0.000026739159,0.000017454084,0.00041175942],"genre_scores_gemma":[0.99643743,0.00007903187,0.0011482169,0.0014214473,0.00006178525,0.00001562721,0.00080013066,0.000013548958,0.000022755463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894595,0.000027680508,0.00034612563,0.00030138562,0.000043885862,0.00033495127],"domain_scores_gemma":[0.9995783,0.0000103698285,0.00006732826,0.00029739787,0.000016721457,0.000029905741],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013657652,0.0001881685,0.00021378747,0.00008220288,0.000030022444,0.000008666134,0.00023564973,0.0001959905,0.000008308943],"category_scores_gemma":[0.000011943858,0.0001894264,0.000058815218,0.000130422,0.00006846513,0.0000033815256,0.000024084497,0.0001293118,0.0000054627158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075242584,0.00005191059,0.000059249054,0.000015040522,0.000013126098,6.483882e-7,0.00015109069,0.0038086607,0.9900553,0.0002080103,0.0042817574,0.0012799198],"study_design_scores_gemma":[0.0009394168,0.00019660199,0.00010565135,0.0000050581493,0.000011424098,0.000019334699,0.000034099827,0.00035683866,0.9912785,0.00010705925,0.0067318445,0.00021411433],"about_ca_topic_score_codex":0.0000054701245,"about_ca_topic_score_gemma":0.00000448282,"teacher_disagreement_score":0.070754334,"about_ca_system_score_codex":0.000022158143,"about_ca_system_score_gemma":0.000016321443,"threshold_uncertainty_score":0.77245843},"labels":[],"label_agreement":null},{"id":"W2109122063","doi":"10.2741/singwi","title":"Potential nuclease-based strategies for HIV gene therapy","year":2000,"lang":"en","type":"review","venue":"Frontiers in bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Genetic enhancement; Nuclease; Gene; Biology; Genome editing; RNA; Virus; Gene delivery; Virology; Lentivirus; Computational biology; Genome; Genetics; Viral disease","score_opus":0.014796972246602893,"score_gpt":0.31383597347875175,"score_spread":0.2990390012321489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109122063","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000056417226,0.81764287,0.18096073,0.000011272868,0.00065914926,0.00047393338,0.00010262139,0.000012055555,0.00008095065],"genre_scores_gemma":[0.00024048369,0.9794296,0.0195147,0.000064615546,0.0002204874,0.00010378943,0.00020348413,0.000039464532,0.0001833866],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860835,0.000042300413,0.00028289683,0.0005739201,0.00012451569,0.00036803875],"domain_scores_gemma":[0.99945045,0.0000070256765,0.000075857846,0.00037435768,0.000021153915,0.00007117119],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018894237,0.0002971557,0.00047242182,0.00014969945,0.00006673645,0.00006870969,0.0005100603,0.0002752282,0.000009882158],"category_scores_gemma":[0.00001539653,0.0002628656,0.00027782266,0.00021072362,0.00013601297,0.000004166144,0.000030706367,0.00010250046,0.0000027853646],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032720036,0.000053255768,0.0000074458962,0.0007704408,0.000027792554,0.000005241961,0.000010202483,0.0011029777,0.0014664952,0.000006714976,0.008262339,0.98825437],"study_design_scores_gemma":[0.00030329693,0.0001025368,0.000004087113,0.0002716053,0.000030353218,0.000006563599,0.000019446756,0.0007419391,0.0009748552,0.00002737095,0.9971763,0.00034165822],"about_ca_topic_score_codex":0.000002766653,"about_ca_topic_score_gemma":0.0000013183786,"teacher_disagreement_score":0.98891395,"about_ca_system_score_codex":0.000026248183,"about_ca_system_score_gemma":0.0003938862,"threshold_uncertainty_score":0.99998236},"labels":[],"label_agreement":null},{"id":"W2109427618","doi":"10.1101/gr.152744.112","title":"Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase","year":2013,"lang":"en","type":"article","venue":"Genome Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Hong Kong Polytechnic University; Ministry of Education, Culture, Sports, Science and Technology; Institute of Genetics; Wellcome Trust","keywords":"Biology; Loss of heterozygosity; Genetics; Breakpoint; Comparative genomic hybridization; Bacterial artificial chromosome; Chromosomal fragile site; Copy-number variation; Chromothripsis; Genome instability; Molecular biology; Chromosome; Gene; Genome; DNA; DNA damage; Allele","score_opus":0.015499439242145401,"score_gpt":0.3203143875748697,"score_spread":0.30481494833272427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109427618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99411625,0.0037442688,0.0012151882,0.000081628044,0.000031840067,0.00052159076,0.000116443625,0.000004496353,0.00016831758],"genre_scores_gemma":[0.99635327,0.0013208336,0.00047605764,0.00001649501,0.000022493461,0.000057613626,0.00022188238,0.000025428262,0.0015059431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985144,0.00008596677,0.00033832082,0.00032136714,0.00028474326,0.00045519386],"domain_scores_gemma":[0.99911904,0.00002035356,0.000051106206,0.00045979326,0.00022159303,0.00012813824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043948114,0.00012873793,0.00020913666,0.00012583453,0.00003971566,0.000008548625,0.00030402374,0.00012142683,0.00030278417],"category_scores_gemma":[0.000033894426,0.00012867223,0.00007276088,0.00015827795,0.00018428518,0.0000025468744,0.00015268395,0.00012850214,0.00007476102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003606104,0.00016124512,0.00029411408,0.00011221012,0.0000986946,0.0000051518496,0.0001197328,0.000038709135,0.9977606,0.0000011568886,0.0010325399,0.0003397981],"study_design_scores_gemma":[0.0006314316,0.00064927584,0.0031496724,0.000011026299,0.000008526043,0.000019732934,0.000114115865,0.000022023636,0.9892356,0.000005617449,0.0060235197,0.00012948997],"about_ca_topic_score_codex":0.00018168821,"about_ca_topic_score_gemma":0.0000065382824,"teacher_disagreement_score":0.008525019,"about_ca_system_score_codex":0.000025415755,"about_ca_system_score_gemma":0.00005639828,"threshold_uncertainty_score":0.5247101},"labels":[],"label_agreement":null},{"id":"W2109678687","doi":"10.1093/dnares/dsm012","title":"Radiation Hybrid Maps of Medaka Chromosomes LG 12, 17, and 22","year":2007,"lang":"en","type":"article","venue":"DNA Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; University of Ottawa","funders":"Exploratory Research for Advanced Technology; Japan Science and Technology Agency","keywords":"Biology; Genetics; Genome; Radiation hybrid mapping; Gene mapping; Chromosome; Cloning (programming); Genotyping; Gene; Bacterial artificial chromosome; Computational biology; Genotype","score_opus":0.019594325042762272,"score_gpt":0.3675101374839045,"score_spread":0.3479158124411422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109678687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99295956,0.0028645261,0.0015362261,0.000091154914,0.000046771493,0.00011539192,0.00001600187,0.0000049638647,0.00236542],"genre_scores_gemma":[0.9978961,0.0006690139,0.0002569147,0.000012455143,0.00015950689,0.000004581706,0.000073094176,0.000010728315,0.0009176197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999255,0.00002637396,0.00011757872,0.00016735292,0.00019588176,0.00023781412],"domain_scores_gemma":[0.9996232,0.00003264823,0.000015224637,0.00018433624,0.00006939895,0.000075225005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007229018,0.000058087604,0.000072709605,0.00008515593,0.000040822393,0.00000964744,0.0000915236,0.000055014043,0.000025366118],"category_scores_gemma":[0.0001063171,0.000057301888,0.00002487252,0.00007413199,0.00007619288,0.0000016891266,0.00008432461,0.000086452965,0.0000033586286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003983638,0.000022950793,0.0030772637,0.000040172494,0.000020241216,0.0000056548706,0.000059448146,0.000024479476,0.96693283,0.000060952367,0.0046976362,0.025018549],"study_design_scores_gemma":[0.00028356712,0.00015730997,0.017853724,0.0000072911807,0.000002494516,0.000010130281,0.00007476849,0.000057362602,0.92964,0.00008164249,0.05176387,0.0000678577],"about_ca_topic_score_codex":0.000022814153,"about_ca_topic_score_gemma":0.00002030822,"teacher_disagreement_score":0.04706623,"about_ca_system_score_codex":0.000008799806,"about_ca_system_score_gemma":0.000028298322,"threshold_uncertainty_score":0.23367031},"labels":[],"label_agreement":null},{"id":"W2109724615","doi":"10.1534/g3.114.011445","title":"The I-TevI Nuclease and Linker Domains Contribute to the Specificity of Monomeric TALENs","year":2014,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Genomics; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Ontario Genomics Institute; National Institutes of Health","keywords":"Nuclease; Transcription activator-like effector nuclease; Genome editing; Biology; Linker; Homing endonuclease; DNA; Computational biology; Genetics; Cleave; Genome; Sequence motif; Cleavage (geology); Endonuclease; Gene; Computer science","score_opus":0.005970219268871961,"score_gpt":0.24854737303005123,"score_spread":0.24257715376117928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109724615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68242717,0.28621462,0.029373897,0.0007046199,0.00036909408,0.00046353578,0.00006176213,0.000013748552,0.00037157105],"genre_scores_gemma":[0.9313044,0.065821715,0.0016253642,0.0002727674,0.0005463309,0.000023527622,0.000018907776,0.000036177826,0.0003507942],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987923,0.00006915359,0.000300279,0.00032654376,0.0001514341,0.00036030164],"domain_scores_gemma":[0.99886507,0.00005474623,0.00008642143,0.00073789974,0.000106310305,0.00014956092],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034149687,0.00020792674,0.00019069538,0.000030985942,0.00021830965,0.00004659618,0.00037569925,0.00009622317,0.000007112094],"category_scores_gemma":[0.00002417529,0.00014187481,0.00009552447,0.00012333137,0.00015670632,0.0000013391804,0.00028766345,0.000077531884,0.000013175299],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058875637,0.000028972876,0.004399619,0.000029323994,0.00011300191,8.1496233e-7,0.00021566862,0.008773205,0.31236908,0.00018283458,0.0011950067,0.6726336],"study_design_scores_gemma":[0.00030014123,0.0002541609,0.008868615,0.000004916537,0.000040717332,0.000011333243,0.00013143367,0.0009880624,0.084152184,0.00005565883,0.90497667,0.00021608552],"about_ca_topic_score_codex":0.000007238821,"about_ca_topic_score_gemma":0.000065129054,"teacher_disagreement_score":0.90378165,"about_ca_system_score_codex":0.000009040147,"about_ca_system_score_gemma":0.000029908739,"threshold_uncertainty_score":0.57854867},"labels":[],"label_agreement":null},{"id":"W2110105435","doi":"10.1093/oxfordjournals.molbev.a004046","title":"Prokaryotic Evolution in Light of Gene Transfer","year":2002,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":998,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Aeronautics and Space Administration; Health Canada; Canada Research Chairs; Canadian Institute for Advanced Research; Canadian Institutes of Health Research; David and Lucile Packard Foundation","keywords":"Biology; Horizontal gene transfer; Evolutionary biology; Gene; Genome; Genetics; Phylogenetics; Gene duplication; Gene pool; Phylogenetic tree; Adaptation (eye); Tree of life (biology); Diversification (marketing strategy); Homology (biology); Gene conversion; Genetic diversity","score_opus":0.0041246976002515525,"score_gpt":0.24194083545985193,"score_spread":0.23781613785960037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110105435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78864056,0.00801876,0.20261352,0.00009329449,0.00006845001,0.00011538423,0.000004247247,0.000006451368,0.0004393508],"genre_scores_gemma":[0.99914086,0.00014140528,0.00054109405,0.000023259965,0.000036517853,0.000013245584,0.000024895604,0.000009024219,0.00006970049],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999344,0.00004830859,0.00016790332,0.00022855832,0.00003774735,0.00017348456],"domain_scores_gemma":[0.9997724,0.0000029466266,0.000016697539,0.0001477473,0.000025994414,0.000034181194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009299682,0.00010221516,0.000115467585,0.000080611884,0.000023563442,0.0000021266642,0.000058453166,0.00018564035,0.000009343234],"category_scores_gemma":[0.000024869456,0.00010294372,0.000044022967,0.00009851696,0.00005948426,0.0000023418975,0.00001948303,0.000062223495,0.0000026972164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019795873,0.000045000616,0.014317313,0.000018028248,0.000016213993,0.0000017187899,0.000034907378,0.00033781066,0.9829102,0.0018630314,0.000022487027,0.00041345452],"study_design_scores_gemma":[0.0010553406,0.00053096336,0.08978911,0.000024293138,0.000030191935,0.00004769489,0.000037826445,0.0023517723,0.9039302,0.0010435204,0.00087437563,0.0002847198],"about_ca_topic_score_codex":0.000018813555,"about_ca_topic_score_gemma":0.000021254225,"teacher_disagreement_score":0.21050031,"about_ca_system_score_codex":0.000014467702,"about_ca_system_score_gemma":0.000008686586,"threshold_uncertainty_score":0.4197923},"labels":[],"label_agreement":null},{"id":"W2110560640","doi":"10.1177/0963662510362834","title":"Attitudes towards the use of genetically modified animals in research","year":2010,"lang":"en","type":"article","venue":"Public Understanding of Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Genome British Columbia; Genome Canada","keywords":"Genetically modified organism; Demographics; Agriculture; Genetically modified maize; Biotechnology; Biology; Genetically modified crops; Sociology; Demography; Transgene","score_opus":0.3381699158898848,"score_gpt":0.42899045343867487,"score_spread":0.09082053754879005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110560640","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9769667,0.000084251486,0.021182507,0.0004988868,0.00009545355,0.00011515745,0.0000031694374,0.0000032295754,0.001050642],"genre_scores_gemma":[0.997367,0.000045266694,0.0025138773,0.000012484901,0.000025192496,0.000004209816,7.65899e-7,0.0000055926,0.000025607125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988178,0.000029665578,0.0001837959,0.00023082396,0.0004255267,0.0003124114],"domain_scores_gemma":[0.99930364,0.000058923357,0.000036615613,0.00034560365,0.00018542852,0.00006981472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018981198,0.00006233629,0.00008623627,0.00020212126,0.00012043534,0.00006917439,0.00052246446,0.000058049474,0.000008373968],"category_scores_gemma":[0.0009306839,0.000047141166,0.00002889039,0.0006767426,0.00221703,0.0000110594465,0.00023547189,0.00015745554,2.660121e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008465888,0.000026463324,0.004686641,0.000011769479,0.0000038553176,2.5977178e-7,0.00012909826,0.0003961144,0.97453696,0.019649398,0.000043545726,0.0005074234],"study_design_scores_gemma":[0.0004085139,0.0002868589,0.09992103,0.000029810557,0.0000044175795,0.000009681946,0.00082345976,0.00529609,0.88874656,0.0023756914,0.001900221,0.00019766937],"about_ca_topic_score_codex":0.00005951495,"about_ca_topic_score_gemma":0.0001780307,"teacher_disagreement_score":0.09523439,"about_ca_system_score_codex":0.0000247506,"about_ca_system_score_gemma":0.00028663286,"threshold_uncertainty_score":0.8168739},"labels":[{"model":"gemma","categories":["sts"],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"split"},{"id":"W2110714217","doi":"10.1007/s00239-009-9201-1","title":"Comparative Genomics of Phylogenetically Diverse Unicellular Eukaryotes Provide New Insights into the Genetic Basis for the Evolution of the Programmed Cell Death Machinery","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Biology; Evolutionary biology; Genomics; Comparative genomics; Biological evolution; Computational biology; Genetics; Genome; Gene","score_opus":0.008491949900268319,"score_gpt":0.2555459587444538,"score_spread":0.24705400884418546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110714217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6778286,0.017004767,0.30437693,0.00024395247,0.00010512379,0.00041450356,0.000002596261,0.0000017299334,0.000021780328],"genre_scores_gemma":[0.9911273,0.00026558235,0.00835104,0.000048012087,0.00015738043,0.000005579238,0.0000035007938,0.000012691644,0.000028905324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987987,0.00012389533,0.00047875554,0.00015722649,0.00026314732,0.00017822013],"domain_scores_gemma":[0.99875575,0.00004930902,0.0004388844,0.00037948746,0.00031265992,0.00006390562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000255849,0.00016667834,0.00022068043,0.00005547391,0.00011146019,0.000013764154,0.00047515734,0.00010707089,0.0000012559545],"category_scores_gemma":[0.00011040038,0.00009449472,0.0003289428,0.00016724592,0.000113642214,0.000005617331,0.00007866332,0.00014799512,2.3265265e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015181073,0.00008583489,0.000712759,0.00002285301,0.00011290872,8.6932204e-7,0.00042046816,0.05324406,0.9424533,0.00017748623,0.00009935796,0.0025182695],"study_design_scores_gemma":[0.00089447625,0.0009418418,0.054294035,0.00004697146,0.0004006266,0.000023747354,0.0005316746,0.0074415435,0.9317521,0.0018685702,0.0016438626,0.00016058155],"about_ca_topic_score_codex":0.00007116496,"about_ca_topic_score_gemma":0.00003702035,"teacher_disagreement_score":0.3132987,"about_ca_system_score_codex":0.00009073467,"about_ca_system_score_gemma":0.00034535554,"threshold_uncertainty_score":0.38533825},"labels":[],"label_agreement":null},{"id":"W2111366005","doi":"10.1016/j.dnarep.2015.09.019","title":"Immuno-capture of UVDE generated 3’-OH ends at UV photoproducts","year":2015,"lang":"en","type":"review","venue":"DNA repair","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Pyrimidine dimer; Biology; DNA; Biotinylation; Endonuclease; DNA damage; Molecular biology; Genome; DNA repair; DNA sequencing; Computational biology; Biochemistry; Gene","score_opus":0.021825649079562588,"score_gpt":0.3295638018819215,"score_spread":0.30773815280235894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111366005","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008911641,0.9967272,0.000040574814,0.000006819499,0.0004694694,0.00036215683,0.00011589063,0.000054646636,0.0013320311],"genre_scores_gemma":[0.00031736644,0.98989534,0.0005480276,0.000022105101,0.00043744643,0.000052302366,0.0015014748,0.0000901432,0.007135763],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99832135,0.00007587153,0.00051093544,0.00060172164,0.0001866943,0.00030343595],"domain_scores_gemma":[0.9984585,0.000007279151,0.00020859724,0.0010577101,0.00015640628,0.000111499096],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002724867,0.0004308167,0.00092443393,0.00007867493,0.000035438257,0.000008731796,0.00030443878,0.0005518334,0.000046665744],"category_scores_gemma":[0.00008004909,0.00037235327,0.00055861805,0.00019487501,0.000055710687,0.0000017315987,0.0002670398,0.00018075724,0.00002860375],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110473506,0.00031122987,0.000023691322,0.027427558,0.0029009678,0.00009398635,0.00028971894,0.00019780284,0.25996926,0.000050779203,0.20324323,0.5053813],"study_design_scores_gemma":[0.00016592149,0.00009004618,0.0000020959517,0.00050116295,0.00025443648,0.000082795224,0.0000061347264,0.0000085350475,0.032806456,0.0000014041889,0.96571004,0.00037095632],"about_ca_topic_score_codex":0.000016905124,"about_ca_topic_score_gemma":0.000009647681,"teacher_disagreement_score":0.76246685,"about_ca_system_score_codex":0.000053627224,"about_ca_system_score_gemma":0.00021657755,"threshold_uncertainty_score":0.99987286},"labels":[],"label_agreement":null},{"id":"W2111434929","doi":"10.1534/g3.112.004754","title":"<i>Saccharomyces cerevisiae</i>Genetics Predicts Candidate Therapeutic Genetic Interactions at the Mammalian Replication Fork","year":2013,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Foundation; National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC","keywords":"Replication (statistics); Genetics; Saccharomyces cerevisiae; Fork (system call); Biology; Gene; Computer science; Virology","score_opus":0.010688505561725252,"score_gpt":0.2819280830686184,"score_spread":0.27123957750689315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111434929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56053424,0.42753237,0.007945047,0.000831748,0.0007461084,0.0013459348,0.00008052585,0.00007007401,0.00091391953],"genre_scores_gemma":[0.9000032,0.09049905,0.0028199707,0.00069480704,0.0009095406,0.00040810317,0.00029449264,0.00012918927,0.004241666],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972192,0.00011578511,0.00063145446,0.00095617434,0.0003351194,0.00074228924],"domain_scores_gemma":[0.9970271,0.000039982413,0.00022925007,0.0022095896,0.00023333325,0.00026077224],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019308893,0.00048683936,0.0002901944,0.000092214585,0.00042709472,0.00016978424,0.00079065823,0.00021678676,0.00031907653],"category_scores_gemma":[0.000009829412,0.00042077832,0.00022774003,0.00026116258,0.00018697561,0.000009907695,0.00048666942,0.00018243496,0.0002768204],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001933271,0.00004209964,0.014515662,0.000045080647,0.00016030802,0.0000014851074,0.00016854942,0.00606764,0.4048747,0.000009447943,0.0034589395,0.57063675],"study_design_scores_gemma":[0.0004916866,0.0003282861,0.02404965,0.000016279542,0.00015857974,0.00013676716,0.00019870549,0.0018349664,0.26517573,0.00013303835,0.7068313,0.00064500887],"about_ca_topic_score_codex":0.00005502061,"about_ca_topic_score_gemma":0.00028571193,"teacher_disagreement_score":0.70337236,"about_ca_system_score_codex":0.00007314882,"about_ca_system_score_gemma":0.00010439124,"threshold_uncertainty_score":0.9998244},"labels":[],"label_agreement":null},{"id":"W2111687551","doi":"10.1038/embor.2009.131","title":"Synthetic biology and patents","year":2009,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Patentability; European patent office; Intellectual property; Monopoly; Patent office; Patentable subject matter; TRIPS architecture; Novelty; Position (finance); Subject (documents); Investment (military); Exclusive right; Political science; Business; Law; Law and economics; Patent law; Sociology; Economics; Computer science; Library science; Finance","score_opus":0.005894079345364658,"score_gpt":0.29022970860103225,"score_spread":0.2843356292556676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111687551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99252677,0.0014893024,0.0027701454,0.000112632464,0.00016214357,0.00006252926,9.994359e-7,0.000014553605,0.0028609023],"genre_scores_gemma":[0.9989316,0.00011210073,0.0003877925,0.00013149966,0.00009109416,0.0000026928378,0.000018980158,0.000006207535,0.00031805204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994873,0.00000794537,0.000121475,0.00022233013,0.000031850952,0.00012912012],"domain_scores_gemma":[0.9996865,0.0000019172735,0.000030350528,0.0002139989,0.000015408052,0.000051833173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075640244,0.000075049764,0.00007431612,0.000017873714,0.000024961935,0.0000076048796,0.000028167387,0.00006839146,0.00001108397],"category_scores_gemma":[0.00003984333,0.000069069865,0.000026735152,0.000022277987,0.000018925364,7.2763726e-7,0.000024349463,0.000030160678,0.0000016106511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007243457,0.000028106113,0.012975219,0.000006151986,0.000017844837,0.000069775444,0.000024606541,0.000058605274,0.95698303,0.000080069716,0.0008751285,0.02887422],"study_design_scores_gemma":[0.00036050737,0.0006630752,0.16344516,0.000025676283,0.00003560746,0.002029248,0.000030795032,0.000105445055,0.7123882,0.0029423705,0.1174427,0.0005312108],"about_ca_topic_score_codex":0.000003434934,"about_ca_topic_score_gemma":0.0000013337154,"teacher_disagreement_score":0.24459481,"about_ca_system_score_codex":0.0000020627324,"about_ca_system_score_gemma":0.00000870888,"threshold_uncertainty_score":0.28165874},"labels":[],"label_agreement":null},{"id":"W2114967484","doi":"10.1186/2048-7010-1-s1-s4","title":"Building trust in biotechnology crops in light of the Arab Spring: a case study of Bt maize in Egypt","year":2012,"lang":"en","type":"article","venue":"Agriculture & Food Security","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto; University Health Network","funders":"","keywords":"Context (archaeology); Agricultural biotechnology; Politics; Private sector; Public relations; Public trust; Public sector; Political science; Agriculture; Business; Biotechnology; Marketing; Economic growth; Geography; Economics; Biology; Ecology","score_opus":0.00549093674520775,"score_gpt":0.2562736352065465,"score_spread":0.25078269846133877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114967484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976196,0.0017779364,0.000027830129,0.00006782364,0.000093315386,0.000340002,0.0000049277783,0.00000498795,0.000063533196],"genre_scores_gemma":[0.99976444,0.000037122765,0.00011203587,0.000008624462,0.000045151395,0.000019367784,0.0000013122694,0.0000073183187,0.000004648692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908733,0.000060005656,0.0003056232,0.00020733076,0.00008486263,0.00025483797],"domain_scores_gemma":[0.9995744,0.000008946594,0.00007796228,0.0002837466,0.000023275385,0.000031626416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019818214,0.00014058057,0.00021481971,0.000076226876,0.000016167738,0.0000032835064,0.00019454904,0.00024676023,0.0000014042674],"category_scores_gemma":[0.000054786226,0.000095632175,0.000055830693,0.0003854353,0.000024151988,0.000004290201,0.00017837805,0.00024129456,1.5838715e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000308097,0.0010170486,0.24405558,0.00006238775,0.00003396157,0.00004020582,0.0035877337,0.00037553904,0.7499026,0.00064673845,0.00002294409,0.000224459],"study_design_scores_gemma":[0.0012342511,0.00044929027,0.16008493,0.000048843598,0.00001721795,0.00017263337,0.0052620885,0.000014938822,0.83102167,0.00004636015,0.001447585,0.0002002002],"about_ca_topic_score_codex":0.0008539721,"about_ca_topic_score_gemma":0.015293048,"teacher_disagreement_score":0.08397066,"about_ca_system_score_codex":0.000019434587,"about_ca_system_score_gemma":0.000011686803,"threshold_uncertainty_score":0.85338795},"labels":[],"label_agreement":null},{"id":"W2115971184","doi":"10.1152/physiolgenomics.00114.2001","title":"Programmed cell death takes flight: genetic and genomic approaches to gene discovery in<i>Drosophila</i>","year":2002,"lang":"en","type":"review","venue":"Physiological Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Drosophila melanogaster; Programmed cell death; Gene; Drosophila (subgenus); Genetics; Genetic screen; Model organism; Genomics; Computational biology; Genome; Phenotype; Apoptosis","score_opus":0.08850043709921131,"score_gpt":0.28994736786116054,"score_spread":0.20144693076194925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115971184","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0411229,0.95659804,0.0006405983,0.000011681934,0.00011675658,0.0012189473,0.00008888541,0.000021885677,0.00018028868],"genre_scores_gemma":[0.0124510415,0.9792705,0.006614593,0.00007818361,0.0006067871,0.0003347101,0.00032401018,0.00010218615,0.00021795879],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99739313,0.000096811964,0.0006108415,0.0011553583,0.00010031102,0.00064353354],"domain_scores_gemma":[0.9989766,0.000024967143,0.00014492696,0.00060646,0.000013333071,0.00023372252],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000105661704,0.00069157366,0.0011914189,0.00010372196,0.00006499163,0.00008739605,0.00048605222,0.0005490722,0.0000061673777],"category_scores_gemma":[0.000023872446,0.0005621132,0.000349521,0.00015865176,0.00006762815,0.000003703562,0.0004128125,0.0003041714,0.000030160048],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076278855,0.00072079414,0.00009945199,0.008062304,0.00036783752,0.00006603408,0.00018601656,0.004990498,0.11025677,0.00007900686,0.0003981187,0.8746969],"study_design_scores_gemma":[0.000572238,0.0007948906,0.0016545143,0.0003563219,0.0004086424,0.000088672634,0.000026444442,0.00017731632,0.0024464233,0.00012554279,0.9914126,0.0019363939],"about_ca_topic_score_codex":0.0000052736414,"about_ca_topic_score_gemma":0.0000046196237,"teacher_disagreement_score":0.9910145,"about_ca_system_score_codex":0.00006066203,"about_ca_system_score_gemma":0.000063879204,"threshold_uncertainty_score":0.999683},"labels":[],"label_agreement":null},{"id":"W2116708466","doi":"10.1089/dna.2012.1611","title":"<i>Caenorhabditis elegans</i> Small RNA Pathways Make Their Mark on Chromatin","year":2012,"lang":"en","type":"review","venue":"DNA and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Chromatin; Caenorhabditis elegans; RNA; RNA interference; Genetics; Small RNA; RNA silencing; Gene silencing; Cell biology; Long non-coding RNA; Chromatin remodeling; Gene; Computational biology","score_opus":0.01929984907913602,"score_gpt":0.2772265596895539,"score_spread":0.2579267106104179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116708466","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0035850697,0.9882359,0.00025116827,0.000006841577,0.0005708871,0.00032914386,0.00026322727,0.000024382007,0.006733376],"genre_scores_gemma":[0.008025958,0.9888029,0.00013140374,0.00012920458,0.00094105257,0.00007786467,0.0012586481,0.000070921895,0.0005620374],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983955,0.00012752248,0.00036727532,0.0005673074,0.000041302243,0.00050110277],"domain_scores_gemma":[0.99914825,0.000047545487,0.00014681947,0.00048414612,0.00001972779,0.00015348686],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016848967,0.000521892,0.0008016183,0.00007142181,0.00007114228,0.00001878123,0.00026072087,0.000766379,0.000035651305],"category_scores_gemma":[0.000011815011,0.00040073058,0.00028682488,0.00006784693,0.00008342336,8.605395e-7,0.00016161078,0.0002532721,0.000043605436],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000065218464,0.0000456884,0.000003365933,0.0018517718,0.00008123904,0.0000038493736,0.00002109654,4.5371874e-7,0.04607597,0.00005505185,0.0003385081,0.9515165],"study_design_scores_gemma":[0.00017494817,0.0003183225,0.0000054992356,0.00027458277,0.0001463188,0.000040335835,0.00001102899,0.0000011566331,0.024825834,0.00001639362,0.97373545,0.00045011946],"about_ca_topic_score_codex":0.000006391042,"about_ca_topic_score_gemma":0.000011995928,"teacher_disagreement_score":0.97339696,"about_ca_system_score_codex":0.000012381984,"about_ca_system_score_gemma":0.000056370372,"threshold_uncertainty_score":0.99984443},"labels":[],"label_agreement":null},{"id":"W2118911146","doi":"10.1093/nar/gkt186","title":"The monomeric GIY-YIG homing endonuclease I-BmoI uses a molecular anchor and a flexible tether to sequentially nick DNA","year":2013,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Nuclease; Homing endonuclease; Endonuclease; Cleave; DNA; Biology; Biophysics; Restriction enzyme; Monomer; Crystallography; Biochemistry; Materials science; Chemistry","score_opus":0.021718830542432493,"score_gpt":0.3492081734597112,"score_spread":0.3274893429172787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118911146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99129593,0.0022978801,0.0028240457,0.0009293545,0.00007338555,0.0006006645,0.0000056411664,0.000027345795,0.0019457315],"genre_scores_gemma":[0.9952141,0.00039493458,0.0018692556,0.00022191886,0.00016640774,0.00016248703,0.000005438552,0.00006132612,0.0019041549],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982182,0.00012312115,0.00019820753,0.00046333432,0.00032662295,0.00067053613],"domain_scores_gemma":[0.99884874,0.000053159172,0.000023591374,0.00060219126,0.00018578682,0.0002865078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050863443,0.00017982152,0.0001401434,0.00010410065,0.0003174205,0.00024127135,0.0004096248,0.000119105185,0.000098483164],"category_scores_gemma":[0.00027577346,0.00014466363,0.00007031943,0.0002566512,0.00018393005,0.000009223875,0.0004833764,0.00023373072,0.00015031533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044998134,0.000023360732,0.0004691922,0.00001932266,0.000049169088,0.000006206591,0.00015182572,0.00010521444,0.9736739,0.00007964928,0.0031342297,0.02224293],"study_design_scores_gemma":[0.00082011695,0.0007152589,0.012342636,0.000043203192,0.000018255943,0.000036436795,0.000983123,0.001049333,0.75404227,0.0003532906,0.22908776,0.0005083517],"about_ca_topic_score_codex":0.00016265987,"about_ca_topic_score_gemma":0.000021684285,"teacher_disagreement_score":0.22595352,"about_ca_system_score_codex":0.00002871011,"about_ca_system_score_gemma":0.000081001395,"threshold_uncertainty_score":0.5899212},"labels":[],"label_agreement":null},{"id":"W2118924317","doi":"10.1111/tpj.12202","title":"Site‐specific <scp>T</scp> – <scp>DNA</scp> integration in <i> <scp>A</scp> rabidopsis thaliana </i> mediated by the combined action of <scp>CRE</scp> recombinase and ϕ <scp>C</scp> 31 integrase","year":2013,"lang":"en","type":"article","venue":"The Plant Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Vlaamse regering; Institute of Genetics; Fonds Wetenschappelijk Onderzoek; European Commission","keywords":"Selectable marker; Recombinase; Integrase; Biology; Genome; DNA; Expression cassette; Cre recombinase; Site-specific recombination; Transposable element; Transgene; Genetics; Computational biology; Gene; Vector (molecular biology); Recombination; Recombinant DNA; Genetically modified mouse","score_opus":0.012891355941377325,"score_gpt":0.24081173525665117,"score_spread":0.22792037931527384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118924317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98231864,0.009471272,0.0021131928,0.0002605749,0.0013949978,0.0011141946,0.0004945421,0.000086297594,0.0027462922],"genre_scores_gemma":[0.9755078,0.015373614,0.0003101851,0.00040826394,0.0007713313,0.00014532432,0.0014193156,0.00018067031,0.0058835153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99449337,0.0006914073,0.001535791,0.00096066075,0.0008701896,0.0014485962],"domain_scores_gemma":[0.99320453,0.0035690558,0.0010249116,0.0010682967,0.00047771249,0.00065550755],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019673589,0.0010508425,0.0009830542,0.00044558782,0.0005836508,0.0005471091,0.0011828124,0.0007976939,0.000017136332],"category_scores_gemma":[0.004663511,0.00075955165,0.00043266595,0.00075700175,0.0004179679,0.00011096408,0.00035662146,0.0018486385,0.00009542155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015163404,0.00037785317,0.0025033038,0.00007950033,0.00034425766,0.000043934917,0.0033157729,0.0006647194,0.6287629,0.00007452067,0.36251947,0.0012986298],"study_design_scores_gemma":[0.0053450246,0.0014871621,0.00946115,0.0004872545,0.0004552224,0.0016767802,0.03957148,0.005023654,0.7147021,0.00087040104,0.22072887,0.00019086913],"about_ca_topic_score_codex":0.00030963076,"about_ca_topic_score_gemma":0.00026999,"teacher_disagreement_score":0.14179058,"about_ca_system_score_codex":0.00014784894,"about_ca_system_score_gemma":0.00021128464,"threshold_uncertainty_score":0.99948555},"labels":[],"label_agreement":null},{"id":"W2119304945","doi":"10.1016/j.gde.2013.10.001","title":"Contemporary, yeast-based approaches to understanding human genetic variation","year":2013,"lang":"en","type":"review","venue":"Current Opinion in Genetics & Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Allen Foundation; National Institute of General Medical Sciences; Rita Allen Foundation; Canadian Institute for Advanced Research; Canadian Institutes of Health Research","keywords":"Biology; Genetic variation; Computational biology; Yeast; Genome; Variation (astronomy); Gene; Human genetic variation; Genetics; Human genome; Model organism; Evolutionary biology","score_opus":0.32990992001406305,"score_gpt":0.39903824509028557,"score_spread":0.06912832507622252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119304945","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010818204,0.888505,0.107567914,0.00001595902,0.001985098,0.0016559801,0.000020085781,0.000022495575,0.000119303746],"genre_scores_gemma":[0.0034104947,0.9807606,0.012415803,0.000012823309,0.0006429704,0.000984984,0.0015839873,0.00014078528,0.000047578378],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99719435,0.00012252784,0.001020005,0.0008719216,0.00031657808,0.0004746045],"domain_scores_gemma":[0.9989304,0.000016666005,0.00024168135,0.000548993,0.000035700898,0.00022655874],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026325136,0.0006213405,0.0007371814,0.0004042161,0.00010403947,0.00008926773,0.0004541537,0.0003536742,0.00001834306],"category_scores_gemma":[0.000021139262,0.00063618354,0.00018882257,0.0003049627,0.000034291705,0.0000028578481,0.00026976422,0.000256147,0.000055954282],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013013222,0.00040498964,0.00038393863,0.021083882,0.00028060237,0.0000015697291,0.0005055288,0.0042037177,0.00026318306,0.00025127022,0.0089922175,0.9636161],"study_design_scores_gemma":[0.00037607847,0.00009087654,0.00038392062,0.0039526816,0.00003600724,0.0000033063238,0.000028677145,0.00011578448,0.00022206247,0.000031214502,0.99391824,0.00084117847],"about_ca_topic_score_codex":0.0000043289424,"about_ca_topic_score_gemma":0.0000046647133,"teacher_disagreement_score":0.984926,"about_ca_system_score_codex":0.00030480867,"about_ca_system_score_gemma":0.0007709544,"threshold_uncertainty_score":0.99960893},"labels":[],"label_agreement":null},{"id":"W2119931220","doi":"10.1074/jbc.m306856200","title":"An Evolutionarily Conserved Role for SRm160 in 3′-End Processing That Functions Independently of Exon Junction Complex Formation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Exon; Biology; Genetics; Conserved sequence; Evolutionary biology; Cell biology; Computational biology; Base sequence; Gene","score_opus":0.03167434369570982,"score_gpt":0.29790798183907374,"score_spread":0.2662336381433639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119931220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.947613,0.0007579504,0.051182944,0.000021598264,0.000055643657,0.00007802789,0.000011151497,0.0000036903834,0.000276019],"genre_scores_gemma":[0.99781805,0.00004751145,0.0018994766,0.000017330849,0.00009306911,0.0000065068284,0.00008339554,0.000005953727,0.000028720611],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992816,0.000029413184,0.0003389143,0.000120757075,0.00009574748,0.00013357983],"domain_scores_gemma":[0.9994523,0.000015298661,0.00022740675,0.00009084656,0.00015548448,0.000058661553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000301169,0.00009723908,0.00015831814,0.000030096031,0.000040029507,0.000011182145,0.00009260125,0.0001859939,0.000035335306],"category_scores_gemma":[0.0001267173,0.000081094564,0.00009265401,0.00006313842,0.0000440231,0.000012923302,0.000011757599,0.00010599069,1.975134e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014466619,0.00010388805,0.008777902,0.000048205806,0.000012134918,6.150283e-7,0.000018781726,0.0011953484,0.9887019,0.0000046786977,0.000091227506,0.00090065337],"study_design_scores_gemma":[0.0009510268,0.00036357442,0.026481865,0.000027898495,0.000016143531,0.00012490666,0.0006915333,0.0009177695,0.9671533,0.00017961294,0.002969807,0.0001225372],"about_ca_topic_score_codex":0.0000021245517,"about_ca_topic_score_gemma":0.0000045914567,"teacher_disagreement_score":0.050205063,"about_ca_system_score_codex":0.000027442855,"about_ca_system_score_gemma":0.000059086986,"threshold_uncertainty_score":0.33069405},"labels":[],"label_agreement":null},{"id":"W2120428541","doi":"10.1128/jb.183.1.36-45.2001","title":"The <i>chvH</i> Locus of <i>Agrobacterium</i> Encodes a Homologue of an Elongation Factor Involved in Protein Synthesis","year":2001,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Science Foundation","keywords":"Biology; Mutant; Agrobacterium tumefaciens; Gene; Genetics; Locus (genetics); Elongation factor; Molecular biology; Plasmid; Coding region; Transgene","score_opus":0.008283521991227942,"score_gpt":0.2581144730572058,"score_spread":0.24983095106597786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120428541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99798375,0.00052840926,0.0011168616,0.000100520825,0.0001196907,0.00010751103,0.000010684714,0.0000016938958,0.00003088629],"genre_scores_gemma":[0.9985479,0.0005133937,0.0007753324,0.000017484743,0.00010602674,0.0000072492626,0.0000065537824,0.000011338854,0.000014696935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889797,0.00016321742,0.00057732716,0.00011460608,0.00007860511,0.00016829609],"domain_scores_gemma":[0.9991413,0.000056127938,0.00039786613,0.00020972018,0.00014648466,0.00004854324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036925572,0.0001134891,0.0002853274,0.000078118384,0.000022751397,0.0000068534205,0.00024557463,0.00015261151,0.0000091409365],"category_scores_gemma":[0.00021198446,0.000081932354,0.00009800658,0.00008708971,0.00011448173,0.000009399293,0.00004229526,0.000121134115,3.1273495e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032526423,0.00006676815,0.006480258,0.000020505504,0.000039905073,0.000009947209,0.00007649467,0.00020434806,0.9874499,0.000008064048,0.00000904203,0.005309545],"study_design_scores_gemma":[0.00044060874,0.0008927254,0.06388386,0.00005604558,0.000015224146,0.00012784718,0.00013473556,0.000031065214,0.93254054,0.00006968191,0.0017032777,0.000104367035],"about_ca_topic_score_codex":0.000028827855,"about_ca_topic_score_gemma":0.0001922183,"teacher_disagreement_score":0.0574036,"about_ca_system_score_codex":0.000013370709,"about_ca_system_score_gemma":0.00007803201,"threshold_uncertainty_score":0.33411044},"labels":[],"label_agreement":null},{"id":"W2120500774","doi":"10.1111/j.1525-1438.2003.13350.x","title":"Translational research in ovarian cancer: a must","year":2003,"lang":"en","type":"review","venue":"International Journal of Gynecological Cancer","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"National Cancer Institute","keywords":"Ovarian cancer; Disease; Medicine; Cancer; Stage (stratigraphy); Translational research; Bioinformatics; Epithelial ovarian cancer; Oncology; Internal medicine; Pathology; Biology","score_opus":0.11510850599062485,"score_gpt":0.5107540994854702,"score_spread":0.3956455934948454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120500774","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002870038,0.9965436,0.00042878973,0.00028770184,0.0015578098,0.00017934662,0.00006801452,0.000001549542,0.0006462253],"genre_scores_gemma":[0.0032126459,0.9948385,0.00032012566,0.00008232496,0.0011709807,0.000075784425,0.000028440832,0.000022645872,0.00024856036],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980961,0.00020496914,0.00067784067,0.0002516919,0.0005169923,0.0002523891],"domain_scores_gemma":[0.9989766,0.00013392925,0.00023688587,0.00010672832,0.00045286035,0.000093016686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007482643,0.0001947963,0.0005362678,0.00030479176,0.000026282321,0.00003514996,0.0005841714,0.00036314974,0.0006214834],"category_scores_gemma":[0.00014650045,0.000151657,0.0003411722,0.00019486723,0.00006777867,0.000005043424,0.00006766951,0.00065192307,0.0000043367672],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006848943,0.00015064517,0.0003440252,0.00039911547,0.0004739844,0.00016049287,0.000023418681,0.0012726199,0.00021421908,0.00017461997,0.0023288978,0.9943895],"study_design_scores_gemma":[0.00044448805,0.000114799215,0.00027824545,0.0011568551,0.000050511593,0.00010421314,0.000008282499,0.0000056842578,0.000057637375,0.00010104434,0.9975169,0.0001613467],"about_ca_topic_score_codex":0.000028661236,"about_ca_topic_score_gemma":0.00015633334,"teacher_disagreement_score":0.995188,"about_ca_system_score_codex":0.00021113426,"about_ca_system_score_gemma":0.0008322396,"threshold_uncertainty_score":0.6804808},"labels":[],"label_agreement":null},{"id":"W2121429975","doi":"10.1371/journal.pgen.1000875","title":"Identification of the Regulatory Logic Controlling Salmonella Pathoadaptation by the SsrA-SsrB Two-Component System","year":2010,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; McMaster University","funders":"Ontario Ministry of Research and Innovation; SFU Community Trust Endowment Fund; Canadian Institutes of Health Research; Simon Fraser University","keywords":"Biology; Regulon; Genetics; Salmonella enterica; Gene; Computational biology; Comparative genomics; Effector; Regulatory sequence; Horizontal gene transfer; Regulation of gene expression; Genomics; Genome; Cell biology","score_opus":0.007089028111371358,"score_gpt":0.24191286138255563,"score_spread":0.23482383327118428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121429975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872671,0.0020970851,0.009587248,0.0001023294,0.0004623613,0.00033261994,0.00002292595,0.000013487194,0.00011486349],"genre_scores_gemma":[0.9993166,0.00006191363,0.00021515953,0.00004145823,0.00020058964,0.000026582022,0.000024133964,0.00002199577,0.00009157043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990322,0.00006210374,0.00032495114,0.00021388546,0.00020851931,0.00015836129],"domain_scores_gemma":[0.9990332,0.000022069256,0.00016962527,0.0006258478,0.00011253302,0.000036712732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002600229,0.00012665518,0.00011420652,0.000016238642,0.00010638899,0.000022215398,0.0003076071,0.00010238956,0.0000019035779],"category_scores_gemma":[0.000043351047,0.00008592211,0.000086222644,0.00006799532,0.00008466664,0.0000013927415,0.000067630885,0.00012683852,0.0000032408927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009442434,0.000028044858,0.000429139,0.00003049127,0.000031155203,1.3285005e-7,0.0000689796,0.0060534626,0.99243146,0.00020643331,0.000108817156,0.00060241134],"study_design_scores_gemma":[0.00029419747,0.000027438586,0.0014609323,0.000012238676,0.000057960693,0.000005853952,0.00016069188,0.027532095,0.9693232,0.000042002077,0.0009779513,0.00010544365],"about_ca_topic_score_codex":0.000004176323,"about_ca_topic_score_gemma":0.000016421396,"teacher_disagreement_score":0.023108296,"about_ca_system_score_codex":0.000009775889,"about_ca_system_score_gemma":0.000027600583,"threshold_uncertainty_score":0.35038018},"labels":[],"label_agreement":null},{"id":"W2122260535","doi":"10.1016/j.ymeth.2003.10.011","title":"A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways","year":2004,"lang":"en","type":"article","venue":"Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Complementary DNA; Protein-fragment complementation assay; Bimolecular fluorescence complementation; cDNA library; Complementation; Computational biology; Biology; Green fluorescent protein; Fluorescent protein; Protein–protein interaction; Cell biology; Gene; Biochemistry","score_opus":0.0747204576232641,"score_gpt":0.39261313421417227,"score_spread":0.31789267659090814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122260535","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34927115,0.000032377087,0.6502711,0.000047129608,0.000055096945,0.00020456761,0.000027679394,0.00001223842,0.00007867154],"genre_scores_gemma":[0.6128028,5.80705e-7,0.3868069,0.000089768764,0.000063336855,0.000021904587,0.00018912493,0.00001550685,0.000010071629],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990763,0.000081752965,0.00024356904,0.00025627448,0.00017420568,0.00016790982],"domain_scores_gemma":[0.9996242,0.000017256438,0.00006158561,0.00018210508,0.00003733368,0.000077538214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035485558,0.00013066917,0.00012655296,0.00008240445,0.00005156587,0.000022882383,0.00010446997,0.00006228963,0.000037259146],"category_scores_gemma":[0.000037900554,0.00013618423,0.00007600746,0.00011392595,0.0000157789,0.0000050427716,0.000057215875,0.00007264507,0.0000018093466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008565597,0.00007358773,0.00015448146,0.000026138156,0.000018415732,6.771276e-7,0.000017781107,0.21973608,0.7756121,0.000108890155,0.000020343607,0.004145802],"study_design_scores_gemma":[0.0009366978,0.0002911152,0.016618777,0.00007683253,0.00001054099,0.0000012220889,0.000049318493,0.0048802854,0.97650075,0.00007335824,0.0004181887,0.00014289778],"about_ca_topic_score_codex":0.000017318214,"about_ca_topic_score_gemma":0.0000015034066,"teacher_disagreement_score":0.26353166,"about_ca_system_score_codex":0.000012007213,"about_ca_system_score_gemma":0.00004115856,"threshold_uncertainty_score":0.55534315},"labels":[],"label_agreement":null},{"id":"W2122482725","doi":"10.1371/journal.pone.0118205","title":"CRISPR-cas Subtype I-Fb in Acinetobacter baumannii: Evolution and Utilization for Strain Subtyping","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Folkhälsomyndigheten; Umeå Centre for Microbial Research; Umeå Universitet; Vetenskapsrådet; Public Health Agency","keywords":"CRISPR; Biology; Acinetobacter baumannii; Horizontal gene transfer; Locus (genetics); Subtyping; Plasmid; Outbreak; Genetics; Genome; Virology; Gene; Bacteria","score_opus":0.07402422341158875,"score_gpt":0.31041206817540873,"score_spread":0.23638784476381997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122482725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95567024,0.0013635912,0.042456284,0.00008215203,0.000037384812,0.00023726771,0.00001556597,0.000011675403,0.0001258582],"genre_scores_gemma":[0.99682564,0.00009068653,0.0025629546,0.000035458193,0.0001365678,0.000025333698,0.00013268375,0.000016094946,0.00017458574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994377,0.000013764968,0.000119206416,0.00018857136,0.00007042933,0.00017036287],"domain_scores_gemma":[0.999718,0.000005636444,0.000023809793,0.0001210624,0.00007355917,0.000057947615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001524985,0.00008451883,0.00009571653,0.000044147397,0.00001961377,0.000013061092,0.00004482104,0.00008806707,0.000002666391],"category_scores_gemma":[0.00012983485,0.00009250042,0.000016512107,0.000053861608,0.000015692036,0.0000047027047,0.000029714905,0.000043493248,0.0000017820538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012347972,0.0001969931,0.03533675,0.00012608062,0.000055316512,7.4630276e-7,0.00023960018,0.00021946248,0.9620871,0.00024514712,0.0002371788,0.0011321256],"study_design_scores_gemma":[0.003100121,0.0008188577,0.15280911,0.00016793466,0.00011083105,0.0000074110694,0.0005447685,0.017127221,0.8216957,0.0011512861,0.001884028,0.0005827144],"about_ca_topic_score_codex":0.000015333566,"about_ca_topic_score_gemma":0.00013619932,"teacher_disagreement_score":0.14039141,"about_ca_system_score_codex":0.000022879969,"about_ca_system_score_gemma":0.000031762193,"threshold_uncertainty_score":0.37720576},"labels":[],"label_agreement":null},{"id":"W2123384495","doi":"10.1016/j.ymgme.2010.11.110","title":"MGMT-based Selection of Lentivector Transduced Cells: Application to Fabry Disease","year":2011,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Molecular biology; Biology; Retrovirus; Transfection; Virology; Genetic enhancement; CD34; Complementary DNA; Lipofectamine; Viral vector; Gene; Vector (molecular biology); Stem cell; Virus; Recombinant DNA; Genetics","score_opus":0.006241909019505404,"score_gpt":0.24530770106283947,"score_spread":0.23906579204333406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123384495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5806065,0.0019034969,0.4171003,0.0000144417,0.00006947789,0.00020417158,0.000016544878,0.0000076411325,0.000077396195],"genre_scores_gemma":[0.98996794,0.00015596798,0.009538114,0.00014231683,0.00005676764,0.00005141429,0.000027979426,0.000030248735,0.00002923664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991691,0.000029656447,0.0001806828,0.00032697237,0.00011271651,0.00018085688],"domain_scores_gemma":[0.9994203,0.0000023218074,0.00004241219,0.00025879254,0.00008729698,0.0001889104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007853619,0.00015604065,0.00014152199,0.00007365823,0.000031838157,0.000008222272,0.00010813397,0.0000760839,0.000009345998],"category_scores_gemma":[0.000011035233,0.00016663517,0.000083384155,0.00011958087,0.000032393236,0.0000014821738,0.000035241304,0.000043226646,0.0000020382877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059181617,0.000058922116,0.0003537694,0.000029269153,0.000030180981,8.379735e-7,0.00006085577,0.000976494,0.99179095,0.00016740823,0.000022610793,0.0064495374],"study_design_scores_gemma":[0.000362686,0.00008545801,0.023986513,0.0000059583767,0.00008655367,8.2727684e-7,0.000011506085,0.0011304411,0.96729887,0.000083718616,0.006759114,0.00018834212],"about_ca_topic_score_codex":0.000017956272,"about_ca_topic_score_gemma":0.000008832034,"teacher_disagreement_score":0.40936145,"about_ca_system_score_codex":0.00000307755,"about_ca_system_score_gemma":0.000039835173,"threshold_uncertainty_score":0.6795185},"labels":[],"label_agreement":null},{"id":"W2123472930","doi":"10.1261/rna.052225.115","title":"eIF4AII is dispensable for miRNA-mediated gene silencing","year":2015,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Lady Davis Institute for Medical Research; Canadian Institutes of Health Research; Friedrich Miescher Institute for Biomedical Research; McGill University; Dana-Farber/Harvard Cancer Center","keywords":"Biology; Gene silencing; microRNA; RNA interference; Psychological repression; Untranslated region; CRISPR; Genetics; Translation (biology); Gene expression; Regulation of gene expression; Gene; Three prime untranslated region; Argonaute; Cell biology; RNA; Messenger RNA","score_opus":0.018952550215181635,"score_gpt":0.30667539991279824,"score_spread":0.28772284969761663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123472930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9662059,0.0016624938,0.030315487,0.00013652365,0.00030887,0.00015544062,0.00003944418,0.000019739678,0.0011560933],"genre_scores_gemma":[0.9950745,0.00007192467,0.0027805977,0.0002529077,0.00033963693,0.00002033171,0.000104389466,0.000022703245,0.0013329722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994273,0.0000056145936,0.00010555595,0.00018816895,0.000072216295,0.00020111246],"domain_scores_gemma":[0.99959624,0.000007280408,0.0000228138,0.0002007449,0.00006113958,0.00011180116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009454761,0.000093166105,0.00008572725,0.000018049912,0.000028763694,0.000013228899,0.000097546435,0.00007735297,0.000014023341],"category_scores_gemma":[0.0000691136,0.00009151871,0.000054271688,0.000042181393,0.000012849141,0.0000016121822,0.000042285978,0.000031511063,0.000025021936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024377032,0.0000144563555,0.00024513292,0.00001357782,0.000023155413,0.0000010477983,0.00013734627,0.0003252779,0.97990716,0.0000062052154,0.018318834,0.0009834248],"study_design_scores_gemma":[0.00045379365,0.00012767472,0.00019399932,0.00000592209,0.000012087284,0.0000056905656,0.00008289683,0.00134691,0.9360396,0.000038890474,0.06154754,0.0001449495],"about_ca_topic_score_codex":0.000016928612,"about_ca_topic_score_gemma":0.000007908907,"teacher_disagreement_score":0.04386752,"about_ca_system_score_codex":0.000010795543,"about_ca_system_score_gemma":0.0000407726,"threshold_uncertainty_score":0.37320247},"labels":[],"label_agreement":null},{"id":"W2123954468","doi":"10.1093/nar/gku628","title":"CRISPR-Cas: an efficient tool for genome engineering of virulent bacteriophages","year":2014,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Biology; CRISPR; Virulence; Genome; Bacteriophage; Genome engineering; Cas9; Genetics; Genome editing; Gene; Computational biology; Synthetic biology; Escherichia coli","score_opus":0.018717264199067208,"score_gpt":0.3496555636849159,"score_spread":0.3309382994858487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123954468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9073512,0.00028037338,0.09176332,0.000033983382,0.00008997166,0.00029166107,0.000023096489,0.000015860061,0.00015052294],"genre_scores_gemma":[0.9929081,0.000048368645,0.0064226836,0.000015961938,0.0003113714,0.000056763267,0.000045494682,0.000043262913,0.00014798374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987149,0.00004370356,0.00021375847,0.00033527825,0.0002590242,0.00043328534],"domain_scores_gemma":[0.99913454,0.000042428164,0.000024571253,0.0004894898,0.00019591369,0.00011305883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008915787,0.00013084144,0.00016297016,0.00011473806,0.000074057825,0.000030515175,0.00030561257,0.000122037854,0.000031518368],"category_scores_gemma":[0.00026406688,0.00012990164,0.00008443247,0.00011371331,0.000059769874,0.0000031753798,0.00015312168,0.00012463813,0.000008499981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052616786,0.000058724112,0.00016270463,0.0001107652,0.000022608318,4.866752e-7,0.00010521596,0.009430392,0.9865288,0.00015651782,0.00007931503,0.003291843],"study_design_scores_gemma":[0.0007056724,0.0011642498,0.022246454,0.000024496678,0.000011060541,0.0000063348057,0.000090118025,0.038616218,0.8941014,0.000017440801,0.0427473,0.0002692796],"about_ca_topic_score_codex":0.0000075145717,"about_ca_topic_score_gemma":0.0000021997575,"teacher_disagreement_score":0.09242744,"about_ca_system_score_codex":0.000021320147,"about_ca_system_score_gemma":0.000031260974,"threshold_uncertainty_score":0.5297235},"labels":[],"label_agreement":null},{"id":"W2124078457","doi":"10.1080/15476286.2014.996067","title":"Small indels induced by CRISPR/Cas9 in the 5′ region of microRNA lead to its depletion and Drosha processing retardance","year":2014,"lang":"en","type":"article","venue":"RNA Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Memorial University of Newfoundland; National Natural Science Foundation of China","keywords":"Drosha; Biology; microRNA; CRISPR; Indel; Genetics; Dicer; Ribonuclease III; Phenotype; Biogenesis; Small RNA; Cas9; Computational biology; RNA; RNA interference; Gene; Single-nucleotide polymorphism","score_opus":0.020219161392389152,"score_gpt":0.30206214763093986,"score_spread":0.2818429862385507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124078457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97385734,0.0015630993,0.023747452,0.00048613793,0.000047691334,0.00014103019,0.0000033200004,0.0000046741648,0.00014926339],"genre_scores_gemma":[0.9988861,0.00015079427,0.00038837947,0.0004253044,0.000071897724,0.000014276564,0.000022650245,0.000009587919,0.000030983087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993218,0.00007159853,0.00016425541,0.00024049086,0.00003095668,0.00017086984],"domain_scores_gemma":[0.9997012,0.000015245246,0.000054276035,0.00016304365,0.000037403315,0.000028827053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018520124,0.000101168334,0.0001282495,0.00003787337,0.000027934006,0.0000075500107,0.00013888054,0.00015462257,5.5979035e-7],"category_scores_gemma":[0.000100132434,0.00008105928,0.000021558757,0.00008270165,0.000031875417,0.0000017539294,0.000050052462,0.00008370354,0.0000010072599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025366857,0.000012592408,0.0017103064,0.000025745598,0.000004174727,3.5382854e-7,0.00012667873,0.000018567433,0.9825623,0.000043051776,0.00014287657,0.015327988],"study_design_scores_gemma":[0.00044879073,0.00049013004,0.0113123655,0.00003879447,0.000009224719,0.000030898253,0.00007971277,0.00030770362,0.97187644,0.000082530874,0.015136938,0.00018646132],"about_ca_topic_score_codex":0.00002748382,"about_ca_topic_score_gemma":0.00006852689,"teacher_disagreement_score":0.025028793,"about_ca_system_score_codex":0.0000048744855,"about_ca_system_score_gemma":0.0000126442665,"threshold_uncertainty_score":0.33055016},"labels":[],"label_agreement":null},{"id":"W2124342072","doi":"10.18174/151595","title":"CRISPR-mediated antiviral defence in prokaryotes","year":2010,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Vetenskapsrådet; Institute of Genetics; Keio University; Deutsche Forschungsgemeinschaft; European Commission; Wageningen University and Research; Howard Hughes Medical Institute; Julius-Maximilians-Universität Würzburg; Research Councils UK; Wenner-Gren Stiftelserna; Life Sciences Research Foundation; Montana State University","keywords":"CRISPR; Biology; Computational biology; Genetics; Gene","score_opus":0.0039887085152274055,"score_gpt":0.2937669403868391,"score_spread":0.28977823187161167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124342072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837733,0.00071538374,0.00046746025,0.000016090617,0.00058487774,0.00022407464,0.000012446991,0.00002157768,0.014184813],"genre_scores_gemma":[0.988322,0.00025966772,0.0007924719,0.000040953524,0.00016768501,0.00003709247,0.0023396045,0.000038828555,0.008001664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912345,0.0000113082415,0.00019672069,0.00034569172,0.00009775438,0.00022508815],"domain_scores_gemma":[0.99961406,0.000008081996,0.000044484303,0.00024710415,0.000045155055,0.000041115465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000744678,0.00020651604,0.00016050148,0.000083327024,0.000020025627,0.000018069288,0.00016729167,0.0005031228,0.00004508962],"category_scores_gemma":[0.000105263876,0.00020288338,0.00006746439,0.000085452026,0.000015180261,0.0000014467986,0.000024635736,0.00028236475,0.000024982082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041011746,0.00003597174,0.00366557,0.0000775772,0.000015748668,0.0000055897704,0.000078388584,0.000013940408,0.9926234,0.00002259044,0.000817622,0.0026026126],"study_design_scores_gemma":[0.00030153015,0.00008619601,0.027348567,0.00004353143,0.000012540514,0.000002957021,0.000185814,0.00009570394,0.96096796,0.000036898782,0.01050392,0.00041437734],"about_ca_topic_score_codex":0.000057251804,"about_ca_topic_score_gemma":0.004054349,"teacher_disagreement_score":0.031655412,"about_ca_system_score_codex":0.000004406724,"about_ca_system_score_gemma":0.00007277033,"threshold_uncertainty_score":0.8273344},"labels":[],"label_agreement":null},{"id":"W2125482231","doi":"10.1261/rna.2122010","title":"Dicer's helicase domain is required for accumulation of some, but not all, <i>C. elegans</i> endogenous siRNAs","year":2010,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Utah","keywords":"Dicer; Small interfering RNA; Biology; RNA Helicase A; Trans-acting siRNA; Helicase; RNA interference; RNA silencing; Gene silencing; Cell biology; Argonaute; RNA; Genetics; Molecular biology; Gene","score_opus":0.03629597035382805,"score_gpt":0.33434927744530707,"score_spread":0.29805330709147904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125482231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98261726,0.0003524184,0.016001547,0.00016162689,0.00023399336,0.00023762937,0.000106951695,0.000013006768,0.00027557608],"genre_scores_gemma":[0.99432296,0.0000643159,0.0044403765,0.00039300474,0.00040392438,0.000025913045,0.00009643469,0.000025822297,0.00022726347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928963,0.000008557852,0.00019314067,0.00021697703,0.00009053626,0.00020113848],"domain_scores_gemma":[0.9994629,0.000018421651,0.00006403202,0.0003217566,0.000062933264,0.000069957736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012368284,0.00011623042,0.00012208232,0.000027960821,0.000037371476,0.000011125946,0.0001311047,0.00014266798,0.000014426016],"category_scores_gemma":[0.000054665867,0.00011819651,0.0001032917,0.000033795597,0.000029825396,0.000004355275,0.000042502917,0.00006286358,0.0000033186127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006192581,0.000033813456,0.00003269851,0.00003346891,0.000037609225,0.0000015312465,0.00006941632,0.00007154272,0.9962307,0.00012578716,0.00053624576,0.002765216],"study_design_scores_gemma":[0.00053941057,0.00013976467,0.00010857559,0.0000044657627,0.000022194432,0.000015890153,0.00001617768,0.00014994935,0.95494646,0.00016217792,0.04376366,0.00013126314],"about_ca_topic_score_codex":0.000031204916,"about_ca_topic_score_gemma":0.000027763443,"teacher_disagreement_score":0.043227416,"about_ca_system_score_codex":0.0000044277426,"about_ca_system_score_gemma":0.0000323004,"threshold_uncertainty_score":0.48199138},"labels":[],"label_agreement":null},{"id":"W2125886271","doi":"10.1016/j.ab.2006.09.019","title":"In-gel activity staining of oxidized nicotinamide adenine dinucleotide kinase by blue native polyacrylamide gel electrophoresis","year":2006,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"","keywords":"Polyacrylamide gel electrophoresis; Staining; Gel electrophoresis; Nicotinamide adenine dinucleotide; Chemistry; Polyacrylamide; Electrophoresis; Gel electrophoresis of proteins; Biochemistry; Chromatography; Two-dimensional gel electrophoresis; Molecular biology; NAD+ kinase; Biology; Enzyme; Proteomics; Genetics; Gene","score_opus":0.003028838224774075,"score_gpt":0.26306287736259004,"score_spread":0.260034039137816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125886271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99535006,0.0010928357,0.002450585,0.00018823493,0.000027447722,0.00009907545,0.00006181896,0.000015419582,0.0007145215],"genre_scores_gemma":[0.99770504,0.0000951748,0.0004611211,0.000055859637,0.0001488873,0.000011637911,0.00011660202,0.000033668086,0.0013719805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833214,0.000034300956,0.0003859305,0.00053225376,0.00022794677,0.0004874297],"domain_scores_gemma":[0.9992384,0.00005098298,0.00011325919,0.00038734297,0.00008856815,0.00012149806],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016626537,0.0002857571,0.00034471927,0.00006608274,0.000040385592,0.000018023158,0.0002423841,0.00024625752,0.00004083126],"category_scores_gemma":[0.00024444453,0.0003025281,0.00017466386,0.00027880672,0.00015883966,0.0000061672017,0.00013193875,0.00023097033,0.000002495595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017394594,0.00018277096,0.0015294412,0.000054328353,0.000059658847,0.000014092651,0.000011990773,0.00023519194,0.99474716,0.00004555812,0.002806552,0.00013931085],"study_design_scores_gemma":[0.0008122658,0.000112463764,0.0012355513,0.000027043807,0.00004222854,0.0000093910085,0.00006577761,0.0011999211,0.99542415,0.000059270642,0.00069554994,0.0003163616],"about_ca_topic_score_codex":0.00027511962,"about_ca_topic_score_gemma":0.00003109924,"teacher_disagreement_score":0.0023550075,"about_ca_system_score_codex":0.00008363319,"about_ca_system_score_gemma":0.000090055815,"threshold_uncertainty_score":0.99994266},"labels":[],"label_agreement":null},{"id":"W2126436260","doi":"10.1023/b:trag.0000026074.11859.77","title":"Bi-directional Duplex Promoters with Duplicated Enhancers Significantly Increase Transgene Expression in Grape and Tobacco","year":2004,"lang":"en","type":"article","venue":"Transgenic Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Vineland Research and Innovation Centre","funders":"","keywords":"Promoter; Biology; Enhancer; Reporter gene; Beta-glucuronidase; Upstream activating sequence; Transgene; Green fluorescent protein; Gene; Molecular biology; GUS reporter system; Genetics; Gene expression","score_opus":0.022233038735840704,"score_gpt":0.3470011191730466,"score_spread":0.3247680804372059,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126436260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876558,0.00096636626,0.010478653,0.00022839634,0.000020419118,0.00045170358,0.0000116708825,0.000018633784,0.0001683499],"genre_scores_gemma":[0.99737185,0.000804959,0.0014492996,0.00001648039,0.000053510983,0.000115030125,0.000052708026,0.000030057241,0.00010612434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985056,0.000075821044,0.00018429794,0.00049497595,0.00030545678,0.00043388514],"domain_scores_gemma":[0.99946505,0.00002381658,0.0000143610405,0.00025586065,0.00007481981,0.00016607642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004300932,0.00015938382,0.00014079786,0.00016791635,0.00009424538,0.000026376865,0.00016096934,0.00012934147,0.000030423216],"category_scores_gemma":[0.00002320905,0.0001388787,0.000044201133,0.00037164165,0.00015805263,0.0000067488186,0.00002275918,0.00024374657,0.0000028458353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048990425,0.00008707494,0.00073826715,0.000031931508,0.000025125186,0.000009144162,0.00023906541,0.0028127779,0.99335617,0.00000766245,0.000025665482,0.0021772238],"study_design_scores_gemma":[0.0018573955,0.0004958705,0.010865535,0.00007068642,0.0000069340836,0.00001862477,0.00014462555,0.000057223766,0.9857282,0.000036153724,0.0005189148,0.00019982718],"about_ca_topic_score_codex":0.00020746229,"about_ca_topic_score_gemma":0.00049456966,"teacher_disagreement_score":0.010127268,"about_ca_system_score_codex":0.00003360787,"about_ca_system_score_gemma":0.00016181417,"threshold_uncertainty_score":0.5663309},"labels":[],"label_agreement":null},{"id":"W2126702649","doi":"10.1158/1078-0432.ccr-14-2180","title":"RAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?","year":2015,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK; Francis Crick Institute","keywords":"Synthetic lethality; Biology; Olaparib; RNA interference; Cancer; Mutant; Gene silencing; Small interfering RNA; Gene; Genetic screen; Mutation; Cancer research; Computational biology; Genetics; RNA; Poly ADP ribose polymerase","score_opus":0.2867914726154852,"score_gpt":0.6023166328049955,"score_spread":0.31552516018951027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126702649","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000100921,0.9964634,0.0004329921,0.0001731844,0.00045207806,0.0011148066,0.00011967999,0.000017055729,0.001125842],"genre_scores_gemma":[0.00047488848,0.9933954,0.0001118395,0.000073809315,0.00340241,0.00029200592,0.00013006538,0.00010731157,0.0020123096],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99527794,0.0013390895,0.0009026946,0.000979183,0.0007345054,0.0007666158],"domain_scores_gemma":[0.99689025,0.0006590254,0.00018446447,0.0013730762,0.00055528455,0.00033791357],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0054511786,0.00038850008,0.0011459002,0.00010683114,0.00015701042,0.00009169349,0.0011876114,0.0007394249,0.000104575854],"category_scores_gemma":[0.0020501388,0.00025636348,0.00066901336,0.00042463272,0.0005307572,0.000002360871,0.0010342249,0.0018602859,0.00012259862],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041539704,0.00004363823,0.000019754585,0.002386583,0.00028226542,0.00002532979,0.000020527263,0.000022439568,0.0000372447,0.000028426064,0.024225663,0.9728666],"study_design_scores_gemma":[0.00021865976,0.00022317377,0.000010052619,0.002733678,0.00020790193,0.000029643546,0.00002701025,0.000032221575,0.000027163918,0.000017670425,0.99616635,0.00030648345],"about_ca_topic_score_codex":0.000058542522,"about_ca_topic_score_gemma":0.000034555098,"teacher_disagreement_score":0.9725601,"about_ca_system_score_codex":0.000103613165,"about_ca_system_score_gemma":0.001267085,"threshold_uncertainty_score":0.99998885},"labels":[],"label_agreement":null},{"id":"W2127044742","doi":"10.1111/j.1365-2516.2006.01258.x","title":"Ethical issues in haemophilia","year":2006,"lang":"en","type":"review","venue":"Haemophilia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Queen's University","funders":"","keywords":"Haemophilia; Medicine; Psychological intervention; Population; Haemophilia A; Nursing; Pediatrics; Environmental health","score_opus":0.02529742185477443,"score_gpt":0.3935944787598352,"score_spread":0.3682970569050608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127044742","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000057520567,0.9971533,0.0001890775,0.000107033324,0.00039951244,0.00044691315,0.000051533727,0.00003033887,0.0015647885],"genre_scores_gemma":[0.00015310175,0.99423784,0.00045737685,0.00008779017,0.001037804,0.00008821405,0.0006804732,0.00010568753,0.0031516855],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978269,0.00012524278,0.00063186634,0.0007343412,0.00020594631,0.00047572903],"domain_scores_gemma":[0.998985,0.00002722888,0.00010775419,0.00074106775,0.000036710335,0.00010223539],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00030772414,0.0005364228,0.0011272966,0.00017452287,0.000039274983,0.000034565855,0.00043833142,0.0015245249,0.000034932076],"category_scores_gemma":[0.000109207955,0.0005043689,0.00044990558,0.00024700808,0.00008498914,0.000001446158,0.00021759742,0.0008328024,0.000100697725],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000119968145,0.00010814684,0.000029842848,0.009146808,0.00012685433,0.00015959973,0.000026806229,0.00013909762,0.00021941264,0.00023683217,0.04518244,0.94461215],"study_design_scores_gemma":[0.0001629613,0.000060011116,0.000026739779,0.0016018309,0.00009598104,0.00007441065,0.0000025636768,0.000009367888,0.00018143786,0.00008254018,0.99717003,0.0005321268],"about_ca_topic_score_codex":0.000055623288,"about_ca_topic_score_gemma":0.00011167364,"teacher_disagreement_score":0.95198756,"about_ca_system_score_codex":0.000039808543,"about_ca_system_score_gemma":0.0001380593,"threshold_uncertainty_score":0.9997717},"labels":[],"label_agreement":null},{"id":"W2127110849","doi":"10.1007/s11248-007-9083-1","title":"Biosafety and risk assessment framework for selectable marker genes in transgenic crop plants: a case of the science not supporting the politics","year":2007,"lang":"en","type":"review","venue":"Transgenic Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institució Catalana de Recerca i Estudis Avançats; Universitat de Lleida; Generalitat de Catalunya; Ministerio de Economía y Competitividad; Royal Society of Canada","keywords":"Selectable marker; Biology; Biosafety; Commercialization; Biotechnology; Genetically modified crops; Transgene; Genetics; Gene; Business","score_opus":0.09148221663498644,"score_gpt":0.5041232697771029,"score_spread":0.4126410531421164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127110849","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04053929,0.9437232,0.012906001,0.00008679329,0.00013171509,0.0021320207,0.0003649031,0.0000055572114,0.000110498586],"genre_scores_gemma":[0.14223894,0.85561424,0.0017315437,0.000007814113,0.00012194582,0.0001282755,0.000016595892,0.0000439523,0.000096700336],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970156,0.00032934183,0.0006735956,0.0005866271,0.00044717672,0.00094763614],"domain_scores_gemma":[0.9983007,0.00055584975,0.00012647083,0.0007202917,0.0001789929,0.0001177216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005752852,0.00027762144,0.00052837544,0.00020919346,0.00044113092,0.000058197224,0.0007327079,0.00034958514,0.000010286062],"category_scores_gemma":[0.00028456704,0.00017131577,0.0003072669,0.00074611156,0.0006446121,0.0000046258747,0.00013626381,0.0008567095,3.8740652e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013923696,0.00020011638,0.0002953171,0.01598342,0.0006253725,0.000039420054,0.000898774,0.00023355983,0.015763665,0.0027290403,0.00008251013,0.9630096],"study_design_scores_gemma":[0.00223873,0.0011018643,0.0016466681,0.006588818,0.0012319434,0.001578772,0.0015128026,0.0014950108,0.10244229,0.00095628574,0.87739027,0.0018165675],"about_ca_topic_score_codex":0.00020450972,"about_ca_topic_score_gemma":0.00028269112,"teacher_disagreement_score":0.961193,"about_ca_system_score_codex":0.000065704844,"about_ca_system_score_gemma":0.0011423612,"threshold_uncertainty_score":0.6986054},"labels":[],"label_agreement":null},{"id":"W2127987011","doi":"10.1093/nar/gku573","title":"MegaTevs: single-chain dual nucleases for efficient gene disruption","year":2014,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Nuclease; DNA; Genome editing; Gene; Transcription activator-like effector nuclease; Genetics; DNA repair; Genome; Computational biology; Cell biology; Molecular biology","score_opus":0.03202629017481791,"score_gpt":0.3566033667221462,"score_spread":0.3245770765473283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127987011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9369807,0.00033127159,0.060704328,0.00020743246,0.00015038291,0.00034715325,0.000023008586,0.000029357536,0.0012263621],"genre_scores_gemma":[0.99559814,0.00003677694,0.0028537891,0.000051728388,0.00063261704,0.00005849184,0.0000867834,0.000047706384,0.00063394324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985212,0.00008927874,0.00017393257,0.00039795175,0.00031573832,0.0005019187],"domain_scores_gemma":[0.9991771,0.00006396231,0.000022712442,0.00039989976,0.00019321339,0.00014308687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082044274,0.00013338396,0.00012241604,0.00009774117,0.00018807512,0.000056558238,0.00019387365,0.00014393091,0.000031431846],"category_scores_gemma":[0.0005080787,0.00012892277,0.00009272927,0.00013237842,0.00011627604,0.000002189601,0.00016426791,0.00012519275,0.00003706531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009817295,0.00009779498,0.000110079185,0.000038937338,0.000020344854,8.838093e-7,0.00007846,0.0021214115,0.98129904,0.00032292897,0.001915893,0.013896078],"study_design_scores_gemma":[0.0009077748,0.0011408511,0.0010195134,0.000021176398,0.0000113907845,0.000015928219,0.00018855366,0.020273054,0.8516551,0.00014464685,0.124355346,0.00026663448],"about_ca_topic_score_codex":0.000010469929,"about_ca_topic_score_gemma":0.000007572551,"teacher_disagreement_score":0.12964389,"about_ca_system_score_codex":0.000031718664,"about_ca_system_score_gemma":0.000029708723,"threshold_uncertainty_score":0.5257318},"labels":[],"label_agreement":null},{"id":"W2128888675","doi":"10.2144/000112901","title":"Design of a Single Plasmid-Based Modified Yeast One-Hybrid System for Investigation of in Vivo Protein-Protein and Protein-DNA Interactions","year":2008,"lang":"en","type":"article","venue":"BioTechniques","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Toronto","keywords":"Fusion protein; Two-hybrid screening; Biology; Plasmid; DDB1; DNA; Molecular biology; Protein–protein interaction; In vivo; Retinoblastoma-like protein 1; Gene; Reporter gene; GATAD2B; Cell biology; Gene expression; DNA-binding protein; Biochemistry; Recombinant DNA; Genetics; Transcription factor; Repressor","score_opus":0.03021822175563036,"score_gpt":0.2690320445616162,"score_spread":0.23881382280598587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128888675","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63981515,0.000060598624,0.3588986,0.000022782127,0.000008269661,0.0011239614,0.000027003323,0.000022818862,0.000020814057],"genre_scores_gemma":[0.9344408,0.000004107633,0.065053806,0.000004992603,0.000022321383,0.00040676407,0.000015369249,0.000017079925,0.000034742825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993188,0.000041572846,0.00026073828,0.00019337753,0.00007292151,0.000112592184],"domain_scores_gemma":[0.9995964,0.000008427065,0.00011220909,0.00017539634,0.00007284566,0.000034685643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014113913,0.00011145693,0.0001614004,0.00010293125,0.000026989186,0.0000047905837,0.00007317024,0.00010420187,9.392643e-7],"category_scores_gemma":[0.000047620906,0.00011888388,0.000039490882,0.00007000944,0.000076594006,0.0000047915755,0.000024469606,0.00004894266,7.149984e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012739694,0.000043882384,0.000023119444,0.0003266267,0.000010622408,6.8392455e-7,0.00003141945,0.00028916707,0.9989463,0.000054728924,0.000026843636,0.000119225675],"study_design_scores_gemma":[0.00033056462,0.0004819018,0.000040912768,0.00039883764,0.0000061257524,0.000005461171,0.00001619684,0.0020470538,0.9964065,0.000044908018,0.00010521657,0.00011633852],"about_ca_topic_score_codex":0.00004845805,"about_ca_topic_score_gemma":0.000007984996,"teacher_disagreement_score":0.2946257,"about_ca_system_score_codex":0.000021537233,"about_ca_system_score_gemma":0.00006261503,"threshold_uncertainty_score":0.4847944},"labels":[],"label_agreement":null},{"id":"W2129316099","doi":"10.1186/s40504-014-0006-7","title":"Challenges for the European governance of synthetic biology for human health","year":2014,"lang":"en","type":"article","venue":"Life Sciences Society and Policy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Advancing Health Outcomes; University of British Columbia","funders":"European Commission","keywords":"Corporate governance; Political science; Human health; Environmental planning; Biology; Engineering ethics; Geography; Business; Medicine; Environmental health; Engineering","score_opus":0.03394431142146303,"score_gpt":0.3699603271812944,"score_spread":0.33601601575983137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129316099","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.33076936,0.11915619,0.43051547,0.10139679,0.0008212724,0.0019678196,0.00029899806,0.00005569119,0.015018403],"genre_scores_gemma":[0.9927377,0.00469325,0.0012596727,0.0007385225,0.00048352845,0.000011846387,0.0000031237455,0.0000054417433,0.000066882385],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.999521,0.00002949516,0.000095658455,0.00016180698,0.000031023086,0.00016100812],"domain_scores_gemma":[0.9997126,0.00006240032,0.00005695012,0.00011267365,0.00001665813,0.00003875138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007189623,0.00005730674,0.00007862422,0.000004987495,0.00021549735,0.000005731484,0.0001533977,0.000028465587,3.5290546e-7],"category_scores_gemma":[0.00011165321,0.000039881445,0.00007469756,0.000034961344,0.00025595358,0.0000012345993,0.000041304393,0.000019381074,1.1115233e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023553866,0.00008442226,0.0012575528,0.00083266414,0.0001559623,1.1744283e-8,0.0044520157,0.0014303521,0.17887025,0.42065576,0.00981558,0.38242188],"study_design_scores_gemma":[0.0016549408,0.0037616664,0.034870356,0.00008089648,0.000037674406,0.000007134868,0.0018553537,0.0053610425,0.030252839,0.0107607255,0.9108382,0.0005191574],"about_ca_topic_score_codex":0.000036991445,"about_ca_topic_score_gemma":0.000028446373,"teacher_disagreement_score":0.9010226,"about_ca_system_score_codex":0.000002240523,"about_ca_system_score_gemma":0.00004201737,"threshold_uncertainty_score":0.16574532},"labels":[],"label_agreement":null},{"id":"W2129570958","doi":"10.12691/ajbr-1-4-6","title":"A New Overview on the Old Topic: The Theoretical Analysis of “Combinatorial Strategy” for DNA Recombination","year":2013,"lang":"en","type":"article","venue":"American Journal of Biomedical Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cloning (programming); Computational biology; Recombination; In vitro recombination; Genetics; clone (Java method); Biology; DNA; Gene; Genome; Molecular cloning; Computer science; Complementary DNA","score_opus":0.03302578047455016,"score_gpt":0.41009797741700965,"score_spread":0.37707219694245947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129570958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9692493,0.0004830198,0.015987888,0.013401419,0.00024247271,0.00033412708,0.00000708596,0.000001933036,0.00029274865],"genre_scores_gemma":[0.9988355,0.00031421566,0.00028254377,0.00012564147,0.0003228988,0.000011707394,0.0000059858407,0.0000075767452,0.00009391711],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985448,0.00022571612,0.00031276458,0.000120648474,0.0005693447,0.00022672418],"domain_scores_gemma":[0.99856645,0.0005764083,0.0001180873,0.0002488101,0.00034080257,0.00014943532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016910416,0.000074751035,0.00020913797,0.0001519431,0.000062142695,0.000030998737,0.00043143716,0.00005447174,0.00020571038],"category_scores_gemma":[0.0009668262,0.00003806584,0.00021449299,0.00069067045,0.0005596427,0.0000028996762,0.00006096224,0.00023701979,0.0000019901183],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048863154,0.00044142333,0.0004832353,0.00004382546,0.002345112,0.0000035317814,0.00041561184,0.00016977394,0.14951555,0.15832144,0.03555057,0.65222126],"study_design_scores_gemma":[0.009398689,0.06913107,0.11026579,0.0005503316,0.0022557327,0.0000942336,0.012005065,0.015981877,0.39334264,0.18805641,0.19749108,0.0014270867],"about_ca_topic_score_codex":0.00006327609,"about_ca_topic_score_gemma":0.0000022076786,"teacher_disagreement_score":0.6507942,"about_ca_system_score_codex":0.000017394825,"about_ca_system_score_gemma":0.00015715633,"threshold_uncertainty_score":0.22523846},"labels":[],"label_agreement":null},{"id":"W2130379010","doi":"10.1093/nar/gkp769","title":"Phage T4 mobE promotes trans homing of the defunct homing endonuclease I-TevIII","year":2009,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Government of Ontario","keywords":"Homing endonuclease; Biology; Endonuclease; Genetics; Gene; Gene conversion; DNA; Intron; Terminator (solar); Plasmid; Restriction enzyme; Genome","score_opus":0.02232578083348763,"score_gpt":0.3440259872759837,"score_spread":0.3217002064424961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130379010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930711,0.0012798068,0.0015770112,0.00038386314,0.00007185487,0.000340835,0.000011203696,0.000016136568,0.0032481933],"genre_scores_gemma":[0.99821854,0.00013739725,0.00072504254,0.0000590167,0.0001748976,0.0000103670745,0.0000073308643,0.00002895631,0.0006384469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984298,0.000100532954,0.0002282576,0.00033736945,0.0004158149,0.00048824612],"domain_scores_gemma":[0.9990995,0.000030359,0.00003462315,0.0005938787,0.00013023167,0.0001113933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006264661,0.0001527603,0.00016405887,0.00007935328,0.00018773234,0.00003422435,0.00051445176,0.00014020003,0.000058053036],"category_scores_gemma":[0.00021662995,0.000119505894,0.00015484692,0.00028043377,0.0001521243,0.000005599472,0.00014030549,0.0003052313,0.000009462692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005519558,0.00007502262,0.0015806084,0.000039064704,0.000023554896,0.0000045688876,0.0002545563,0.000100308054,0.97517073,0.00006681391,0.000606763,0.02202284],"study_design_scores_gemma":[0.00062380236,0.0004170928,0.01970213,0.00005752025,0.000014721475,0.000017335935,0.0001929034,0.0006235705,0.96535116,0.00011031097,0.012719396,0.00017007966],"about_ca_topic_score_codex":0.000013247559,"about_ca_topic_score_gemma":0.000009691488,"teacher_disagreement_score":0.02185276,"about_ca_system_score_codex":0.000020165106,"about_ca_system_score_gemma":0.000079832455,"threshold_uncertainty_score":0.48733088},"labels":[],"label_agreement":null},{"id":"W2131046906","doi":"10.1016/s0022-2836(03)00839-8","title":"Different Genome Maintenance Strategies in Human and Tobacco Cells","year":2003,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Novartis Foundation","keywords":"Genome; Computational biology; Human genome; Biology; Biotechnology; Genetics; Evolutionary biology; Gene","score_opus":0.0051883139901973034,"score_gpt":0.2915126381326121,"score_spread":0.28632432414241477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131046906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.965745,0.0031751923,0.030485239,0.000035575467,0.00010751102,0.000051152838,0.0000018515058,0.0000013994655,0.00039708245],"genre_scores_gemma":[0.99835056,0.00039979696,0.0010825444,0.00007467194,0.00004479399,0.0000015912209,0.0000034787618,0.0000108685435,0.00003169453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992936,0.000071994196,0.0002600417,0.0001408094,0.000043929642,0.00018959412],"domain_scores_gemma":[0.9996747,0.000005872869,0.00009171673,0.00012332093,0.000043747063,0.000060681727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001667923,0.00011719001,0.00018333412,0.00007310643,0.000017742743,0.000013650679,0.000104303675,0.000111959955,0.000008301522],"category_scores_gemma":[0.00003018065,0.00009662871,0.000064796004,0.000039258015,0.000053625343,0.0000022354277,0.000033020006,0.0001186687,3.733314e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012945763,0.000026459766,0.0019122707,0.0000066572225,0.000026548678,0.00002611572,0.000020760652,0.0004955335,0.9957883,0.0014549913,0.000019010462,0.00021042558],"study_design_scores_gemma":[0.0009365593,0.0006794391,0.008918297,0.000016619382,0.0000142755935,0.00018741169,0.00019377738,0.0000044083213,0.9805683,0.0016345015,0.006657427,0.00018902127],"about_ca_topic_score_codex":0.0000028628879,"about_ca_topic_score_gemma":0.000013050887,"teacher_disagreement_score":0.032605562,"about_ca_system_score_codex":0.000010197166,"about_ca_system_score_gemma":0.000030337234,"threshold_uncertainty_score":0.39404044},"labels":[],"label_agreement":null},{"id":"W2131573135","doi":"10.15252/msb.20156373","title":"Extensive mapping of an innate immune network with CRISPR","year":2015,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; CRISPR; Innate immune system; Computational biology; Immune system; Genetics; Gene","score_opus":0.010723198620582962,"score_gpt":0.28739126675987753,"score_spread":0.27666806813929457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131573135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.74207205,0.008816377,0.2477772,0.0000271832,0.00040297912,0.0002561675,0.000008860642,0.00002101502,0.0006181906],"genre_scores_gemma":[0.9970871,0.00002710569,0.0023310168,0.00006891856,0.00021436087,0.000030459818,0.00012837925,0.000034184955,0.000078482044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987648,0.00014868114,0.0003092411,0.00035375459,0.000091543094,0.0003319806],"domain_scores_gemma":[0.99896187,0.000005726608,0.00012643078,0.0005189458,0.00025737364,0.00012966567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003074362,0.00019396759,0.00031014837,0.00005677217,0.000028505801,0.000011382521,0.00020863395,0.00019895684,0.000001416476],"category_scores_gemma":[0.000047567195,0.0001661777,0.000058772588,0.00014539498,0.00008816961,0.0000027346637,0.000097559816,0.00008225969,0.0000037002221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008589671,0.00002727479,0.0012027317,0.000040559695,0.00014174642,0.00003013053,0.000089180074,0.03396717,0.96314496,0.00048703502,0.00018550984,0.00059777783],"study_design_scores_gemma":[0.0029750527,0.0039954204,0.0027031917,0.00017824314,0.00008968727,0.0006414278,0.0011883993,0.0043359213,0.9247932,0.00021234552,0.057803992,0.0010831386],"about_ca_topic_score_codex":0.000120206576,"about_ca_topic_score_gemma":0.000011941647,"teacher_disagreement_score":0.25501508,"about_ca_system_score_codex":0.000010804023,"about_ca_system_score_gemma":0.00006823792,"threshold_uncertainty_score":0.677653},"labels":[],"label_agreement":null},{"id":"W2131790399","doi":"10.4161/nucl.2.6.17710","title":"Dare to challenge the silence? Telomeric gene silencing revisited","year":2011,"lang":"en","type":"review","venue":"Nucleus","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Gene silencing; Biology; Genetics; Silence; Gene; Heterochromatin; URA3; Psychological repression; Saccharomyces cerevisiae; Gene expression; Chromatin; Philosophy","score_opus":0.03240536712362648,"score_gpt":0.3350831297886722,"score_spread":0.30267776266504576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131790399","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016295475,0.9960275,0.0006286384,0.000016638278,0.0002575818,0.0005408259,0.00006176241,0.000032019892,0.0022720234],"genre_scores_gemma":[0.0005740584,0.9972847,0.00044994394,0.000097968856,0.0007070333,0.000101245074,0.00011629027,0.000100280966,0.0005684864],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985256,0.000063317726,0.00036333848,0.0005532146,0.00012214293,0.0003723504],"domain_scores_gemma":[0.9987283,0.000017195534,0.0001135344,0.00094876083,0.000053519147,0.0001386888],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017003425,0.00040134694,0.0006128602,0.00005643842,0.00009759262,0.000031911502,0.0006498214,0.00030251514,0.00013192327],"category_scores_gemma":[0.000074219024,0.00028532403,0.000333289,0.00022308521,0.000033241497,0.000001487698,0.00031150313,0.00023262369,0.00018697104],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033718306,0.000019674042,3.2216548e-7,0.001884454,0.00011008664,0.000007221553,0.00015116474,0.000017911689,0.0015270052,0.000012794715,0.001967791,0.9942982],"study_design_scores_gemma":[0.00005254152,0.00010717003,0.00000657012,0.0010757664,0.00017765576,0.000045843546,0.00003857346,0.000002601296,0.0004873191,0.0000031109741,0.99763215,0.0003707179],"about_ca_topic_score_codex":0.000012202897,"about_ca_topic_score_gemma":0.0000023842363,"teacher_disagreement_score":0.99566436,"about_ca_system_score_codex":0.000025447476,"about_ca_system_score_gemma":0.00007808272,"threshold_uncertainty_score":0.9999599},"labels":[],"label_agreement":null},{"id":"W2132508093","doi":"10.15252/embr.201540974","title":"Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network","year":2015,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Stem Cell Network; University of Ottawa; Ottawa Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; Canadian Institutes of Health Research; Government of Ontario","keywords":"Library science; Embryonic stem cell; Biology; Genetics; Gene; Computer science","score_opus":0.008985181240264942,"score_gpt":0.2512108500300247,"score_spread":0.24222566878975976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132508093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711062,0.0028928544,0.02009495,0.00015353932,0.00066236395,0.00039436246,0.0000069691773,0.000032601303,0.0046562175],"genre_scores_gemma":[0.99173874,0.000022682056,0.003215197,0.00021349783,0.0005315512,0.000050067225,0.00006738576,0.00004141306,0.0041194805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988292,0.00003587974,0.0003197438,0.00037568764,0.00016972398,0.00026980197],"domain_scores_gemma":[0.9988196,0.00000809546,0.000186818,0.0007058246,0.00012358969,0.00015607453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046900974,0.00020351834,0.00016087509,0.000022110717,0.00012089072,0.000040690422,0.0001457305,0.00014209637,0.000005796343],"category_scores_gemma":[0.00003086235,0.00015667123,0.00010727089,0.000107771564,0.00006842124,0.0000039508477,0.0001391189,0.00016270461,0.000010327197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000438972,0.00007767645,0.00024393084,0.000011312993,0.00010293657,0.00009594879,0.00081488263,0.04449323,0.9433587,0.0003070987,0.009888704,0.00056167954],"study_design_scores_gemma":[0.00037905702,0.00029636343,0.0012177275,0.00003346945,0.0000673912,0.0011736483,0.00081761053,0.0008309159,0.9681105,0.0005999591,0.026046943,0.00042642097],"about_ca_topic_score_codex":0.00004146191,"about_ca_topic_score_gemma":0.000056718527,"teacher_disagreement_score":0.043662313,"about_ca_system_score_codex":0.000047329668,"about_ca_system_score_gemma":0.00026122647,"threshold_uncertainty_score":0.63888675},"labels":[],"label_agreement":null},{"id":"W2132963469","doi":"10.1093/toxsci/kfm123","title":"Transgenic Rescue of Methotrexate-Induced Teratogenicity in Drosophila melanogaster","year":2007,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Dihydrofolate reductase; Drosophila melanogaster; Methotrexate; Biology; Antifolate; Transgene; Gene; Pharmacology; Genetics; Antimetabolite; Immunology","score_opus":0.036614867266766826,"score_gpt":0.364009946491591,"score_spread":0.3273950792248242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132963469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949912,0.00019693002,0.0024348495,0.000080304875,0.000072264236,0.000100157005,0.0000018654538,0.0000065038776,0.0021159167],"genre_scores_gemma":[0.9978761,0.000023270279,0.0019104404,0.000097079246,0.00004983765,0.0000034476811,0.0000015354581,0.0000031630182,0.00003509646],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990555,0.00004322513,0.00022646354,0.000266965,0.00013520062,0.0002726204],"domain_scores_gemma":[0.99974984,0.000032482265,0.000027164228,0.00011054421,0.00001696604,0.00006297693],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009774038,0.000090251655,0.0001327575,0.000053422034,0.00003804645,0.000008316871,0.00023007613,0.00012872326,0.000042429117],"category_scores_gemma":[0.00008425119,0.00006701034,0.00006299522,0.00024252055,0.00014074222,0.00000284916,0.00005200374,0.00007124516,0.0000019371037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029395818,0.00004924313,0.0049891095,0.0000037963491,0.000003863542,0.0000029102475,0.00004829648,0.0003746222,0.9925571,0.0001223597,0.000006247071,0.0018130351],"study_design_scores_gemma":[0.00021459263,0.0005402047,0.07794355,0.000005077857,0.0000031618083,0.0000048641004,0.000076187716,0.00007109879,0.9206758,0.00012759036,0.00024337874,0.00009449282],"about_ca_topic_score_codex":0.00001527455,"about_ca_topic_score_gemma":0.0002355372,"teacher_disagreement_score":0.07295444,"about_ca_system_score_codex":0.0000071712793,"about_ca_system_score_gemma":0.000024135592,"threshold_uncertainty_score":0.27326024},"labels":[],"label_agreement":null},{"id":"W2133887607","doi":"10.1111/j.1365-2958.2010.07485.x","title":"Identifying your enemies - could envelope stress trigger microbial immunity?","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; CRISPR; Nucleic acid; Innate immune system; Immunity; Genome; Acquired immune system; Archaea; Genetics; Plasmid; Cell envelope; Computational biology; Immune system; Gene; Escherichia coli","score_opus":0.00782194440751011,"score_gpt":0.2852667085102464,"score_spread":0.2774447641027363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133887607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981689,0.0013870382,0.014989998,0.00011028391,0.00096373167,0.0002031122,0.00009224108,0.000040059524,0.0005245673],"genre_scores_gemma":[0.9946839,0.00009265981,0.0034579504,0.00029929608,0.00023623223,0.000020985111,0.0004736228,0.000058311485,0.00067702786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853957,0.0000813391,0.00031738597,0.000508757,0.000045730703,0.0005072449],"domain_scores_gemma":[0.9990701,0.000013468444,0.00008134989,0.0006370155,0.00009969341,0.00009834917],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020183095,0.00030880416,0.00025768156,0.00010601371,0.00015103632,0.000049849776,0.00039167027,0.00048590143,0.00011459594],"category_scores_gemma":[0.00007528399,0.000321368,0.00018076005,0.000110582005,0.00018148679,0.00000418738,0.0003156819,0.00043965335,0.000044839286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024676086,0.00004642667,0.00028427242,0.000024416031,0.00009876076,0.00016851928,0.00008567875,0.00008221724,0.99740016,0.00006959477,0.00089432293,0.0008209566],"study_design_scores_gemma":[0.0005339814,0.00007331923,0.00014346397,0.0000094144,0.00003275854,0.0026035192,0.00008964373,0.000006910481,0.91162395,0.000019353116,0.0845028,0.0003608557],"about_ca_topic_score_codex":0.0000521116,"about_ca_topic_score_gemma":0.00014081143,"teacher_disagreement_score":0.08577618,"about_ca_system_score_codex":0.00001044308,"about_ca_system_score_gemma":0.0000600938,"threshold_uncertainty_score":0.9999238},"labels":[],"label_agreement":null},{"id":"W2133920592","doi":"10.1128/jb.01093-12","title":"Dynamics of the SetCD-Regulated Integration and Excision of Genomic Islands Mobilized by Integrating Conjugative Elements of the SXT/R391 Family","year":2012,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Integrase; Biology; Integrases; Genetics; Chromosome; Gene; Recombination; Horizontal gene transfer; Computational biology; Genome","score_opus":0.005152802224892193,"score_gpt":0.26181017432768267,"score_spread":0.2566573721027905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133920592","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959115,0.0006805329,0.0029552632,0.00006263409,0.00022831514,0.00009411177,0.00003293609,5.4544824e-7,0.00003416272],"genre_scores_gemma":[0.9992426,0.00016027818,0.0004886359,0.00002437127,0.000040087194,9.588341e-7,0.000013852155,0.000007110731,0.000022127126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915594,0.00011496659,0.0004963031,0.00006544487,0.000068286936,0.000099082754],"domain_scores_gemma":[0.9990808,0.000032164324,0.00057925103,0.00014266293,0.0001407148,0.000024404873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032799796,0.00008960128,0.00022706286,0.00002968478,0.000021543257,0.0000023780644,0.00015247538,0.000104393985,0.000005762456],"category_scores_gemma":[0.00010066373,0.000050027666,0.00009546438,0.000048763093,0.000121595556,0.00000531872,0.00009180426,0.00011034797,4.5539593e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088522305,0.00002586314,0.029338745,0.000013291195,0.000062586085,3.1330693e-8,0.00033711377,0.00003644407,0.9685247,0.00001216162,0.00005984032,0.0015007289],"study_design_scores_gemma":[0.00076076976,0.00042420122,0.30035678,0.00007433092,0.000051902964,0.000032903445,0.0008403963,0.00082814635,0.69631875,0.00006065588,0.00018392444,0.00006723497],"about_ca_topic_score_codex":0.000010503671,"about_ca_topic_score_gemma":0.000014078951,"teacher_disagreement_score":0.27220592,"about_ca_system_score_codex":0.000015835943,"about_ca_system_score_gemma":0.000035841633,"threshold_uncertainty_score":0.2040069},"labels":[],"label_agreement":null},{"id":"W2134208169","doi":"10.1161/hh1301.092687","title":"Temporally Regulated and Tissue-Specific Gene Manipulations in the Adult and Embryonic Heart Using a Tamoxifen-Inducible Cre Protein","year":2001,"lang":"en","type":"article","venue":"Circulation Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":712,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"National Institutes of Health; Pew Charitable Trusts","keywords":"Cre recombinase; Transgene; Biology; Recombinase; Gene targeting; Genetically modified mouse; Molecular biology; Tamoxifen; Gene; Cell biology; Cre-Lox recombination; Fusion protein; Gene expression; Mutant; Genetics; Recombinant DNA; Recombination","score_opus":0.07744180967428259,"score_gpt":0.394457242225176,"score_spread":0.3170154325508934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134208169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99488235,0.0015711205,0.0022470865,0.00058087095,0.000015998488,0.0005411164,0.000001901731,0.000007517502,0.00015204586],"genre_scores_gemma":[0.9988883,0.0001127597,0.00063686416,0.000025429841,0.0000983125,0.000032988388,0.000038100057,0.000015958749,0.00015126498],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99894536,0.0001347245,0.00015253869,0.00030538958,0.00021708317,0.0002449329],"domain_scores_gemma":[0.99948156,0.000017407801,0.000019825706,0.00029106956,0.00013466892,0.000055453547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058793183,0.0000895334,0.00008246683,0.00012903388,0.00017596624,0.000082753606,0.000085625186,0.00011045919,0.000011118178],"category_scores_gemma":[0.000062734165,0.00008126179,0.000016691321,0.00034228468,0.00007156834,0.00000853184,0.000059667524,0.00015159659,0.0000023110351],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001718126,0.000021042231,0.016718213,0.000017315155,0.0000057427133,0.000006303927,0.00015980755,0.0037922796,0.9783131,0.00012125396,0.00008887405,0.000738879],"study_design_scores_gemma":[0.0010631543,0.0001731103,0.880523,0.000078527446,0.000007483141,0.0002716969,0.00047121794,0.028189342,0.079995155,0.0007042266,0.008197023,0.00032602987],"about_ca_topic_score_codex":0.00015617027,"about_ca_topic_score_gemma":0.00013569732,"teacher_disagreement_score":0.89831793,"about_ca_system_score_codex":0.000020399497,"about_ca_system_score_gemma":0.000040192906,"threshold_uncertainty_score":0.33137596},"labels":[],"label_agreement":null},{"id":"W2134393172","doi":"10.1016/j.cell.2013.01.056","title":"Interaction Domains of Sos1/Grb2 Are Finely Tuned for Cooperative Control of Embryonic Stem Cell Fate","year":2013,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Hospital for Sick Children; University of Toronto; Ontario Institute for Cancer Research; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Embryonic stem cell; Cell biology; Stem cell; Cell fate determination; Cell; Computational biology; Evolutionary biology; Genetics; Transcription factor; Gene","score_opus":0.0068609779701624815,"score_gpt":0.25131174704948217,"score_spread":0.2444507690793197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134393172","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93642515,0.00076172996,0.061660197,0.000038414455,0.00013612403,0.00036832187,0.00004466049,0.000004676351,0.0005607573],"genre_scores_gemma":[0.99801683,0.000054165008,0.0003571993,0.00003310195,0.000054540797,0.000042681444,0.000030650423,0.0000148020445,0.0013960464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994871,0.00001658236,0.00017619623,0.00015000154,0.000043958964,0.00012615841],"domain_scores_gemma":[0.9995159,0.000022631708,0.00010920915,0.00016654815,0.000149954,0.00003577756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047171354,0.000098933524,0.00015796394,0.00002350794,0.000018335515,0.0000062768268,0.000081386665,0.00007493828,0.000023244198],"category_scores_gemma":[0.000008235949,0.00009130696,0.000084745996,0.000031123847,0.000024065635,0.00000288055,0.000022202405,0.000039543193,0.0000056527942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004759361,0.00004663882,0.00012061288,0.00011344053,0.000022472224,1.520165e-7,0.00006612586,0.0024517248,0.9958586,0.0000043918235,0.0009657007,0.0003025445],"study_design_scores_gemma":[0.0011251096,0.00028552915,0.00047260392,0.000017840122,0.00002202553,7.265847e-7,0.00034564745,0.0016334648,0.9937234,0.000006639637,0.002271541,0.000095476506],"about_ca_topic_score_codex":0.000010585034,"about_ca_topic_score_gemma":0.00000924471,"teacher_disagreement_score":0.061591692,"about_ca_system_score_codex":0.000006076538,"about_ca_system_score_gemma":0.000025009376,"threshold_uncertainty_score":0.37233898},"labels":[],"label_agreement":null},{"id":"W2134424319","doi":"10.1073/pnas.0911908107","title":"Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":217,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Occupational Cancer Research Centre; McGill University Health Centre","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Life Sciences Research Foundation; Damon Runyon Cancer Research Foundation; Howard Hughes Medical Institute","keywords":"Argonaute; Biology; RNA; Genetics; Piwi-interacting RNA; RasiRNA; RNA silencing; Gene silencing; Small RNA; RNA-induced transcriptional silencing; Gene; Trans-acting siRNA; RNA interference","score_opus":0.03226608319730739,"score_gpt":0.29021923798252425,"score_spread":0.25795315478521685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134424319","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972962,0.00027285627,0.00003584766,0.00045507497,0.00006149542,0.00015728896,0.00003286034,0.000002792861,0.0016855653],"genre_scores_gemma":[0.99893445,0.00009654233,0.0007153774,0.00007612075,0.00012220116,0.000011963931,0.0000011490092,0.000004779273,0.000037417718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880904,0.00000834578,0.00028528928,0.00020920296,0.00054191065,0.00014622517],"domain_scores_gemma":[0.9996004,0.000020859305,0.0001891867,0.000018961455,0.00014834017,0.000022213118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000988938,0.00009725821,0.00011057932,0.00009559117,0.00008502817,0.000015628224,0.00072682503,0.00012041167,0.0000049917476],"category_scores_gemma":[0.0001160065,0.00006410894,0.00010253954,0.0002843107,0.0003294286,0.00001537838,0.00006684045,0.0001403173,2.5955924e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014834169,0.00003977851,0.0005236837,0.000028721923,0.000014866796,1.4040329e-8,0.0002551014,0.0003222446,0.9957687,0.0022979055,0.000019979565,0.0007141649],"study_design_scores_gemma":[0.00018469297,0.00006995204,0.009694355,0.000016303517,0.000012514856,0.000013650484,0.00019830314,0.00016916536,0.98802906,0.0013574971,0.00018220946,0.00007226498],"about_ca_topic_score_codex":0.000028011871,"about_ca_topic_score_gemma":0.000004990964,"teacher_disagreement_score":0.009170671,"about_ca_system_score_codex":0.000008459193,"about_ca_system_score_gemma":0.00004403937,"threshold_uncertainty_score":0.26142868},"labels":[],"label_agreement":null},{"id":"W2134500698","doi":"10.1111/bioe.12191","title":"The Ethics of Introducing <scp>GMOs</scp> into sub‐<scp>S</scp>aharan <scp>A</scp>frica: Considerations from the sub‐<scp>S</scp>aharan <scp>A</scp>frican Theory of <i><scp>U</scp>buntu</i>","year":2015,"lang":"en","type":"article","venue":"Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Jackman Humanities Institute, University of Toronto","keywords":"Environmental ethics; Universalism; Context (archaeology); African philosophy; Bioethics; Sociology; Morality; Value (mathematics); Political science; Epistemology; Law; Politics; Geography","score_opus":0.035751223228708134,"score_gpt":0.3065417274238233,"score_spread":0.2707905041951152,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134500698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9266267,0.039133433,0.01533839,0.0018025932,0.003852203,0.0027253234,0.0016617193,0.0004701192,0.008389529],"genre_scores_gemma":[0.97051877,0.011902923,0.004259292,0.0030460055,0.003557754,0.00039929766,0.0013158134,0.0006961881,0.0043039666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98391336,0.0030082753,0.0035475723,0.0032375907,0.002981121,0.0033120578],"domain_scores_gemma":[0.95178455,0.03631048,0.0022733074,0.005033133,0.0030923688,0.0015061701],"candidate_categories":["metaresearch","metaepi_narrow","sts","research_integrity"],"consensus_categories":["metaepi_narrow","sts","research_integrity"],"category_scores_codex":[0.009718181,0.0024769767,0.0024615629,0.0006022351,0.002113097,0.0008291597,0.003516814,0.0037737084,0.0000075484672],"category_scores_gemma":[0.092221744,0.0021071064,0.0014318784,0.0020266792,0.004352488,0.00015988173,0.0019756823,0.0055860756,0.00015506484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030427824,0.0011079641,0.005312732,0.00083990546,0.002529218,0.00009039066,0.05504203,0.004742981,0.6383204,0.016989585,0.27383673,0.0011576375],"study_design_scores_gemma":[0.0025867722,0.0009821393,0.0019764442,0.00037205926,0.0009189756,0.00012407606,0.05025215,0.00073808304,0.60951847,0.009854419,0.3224251,0.0002513089],"about_ca_topic_score_codex":0.0010515391,"about_ca_topic_score_gemma":0.002076598,"teacher_disagreement_score":0.082503565,"about_ca_system_score_codex":0.00030965632,"about_ca_system_score_gemma":0.0026972934,"threshold_uncertainty_score":0.99918604},"labels":[],"label_agreement":null},{"id":"W2134751179","doi":"10.3390/genes5040887","title":"Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives","year":2014,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Canada Research Chairs; McGill University","keywords":"Biology; Mutagenesis; Genome; Gene; Genetics; Phenotype; Immunity; Forward genetics; Computational biology; Human genetics; Mutation; Immune system","score_opus":0.05163272787417625,"score_gpt":0.3965359632209795,"score_spread":0.3449032353468032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134751179","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018776509,0.91039336,0.08693397,0.000015216014,0.00013758178,0.00049731275,0.000033098113,0.000030472469,0.00008133354],"genre_scores_gemma":[0.00017556745,0.9846337,0.0140559785,0.000034996938,0.00038426733,0.000070835944,0.00013750436,0.00007153183,0.00043565992],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984922,0.00026424008,0.00027762007,0.00058550946,0.000086480395,0.000293976],"domain_scores_gemma":[0.99903166,0.000050089882,0.000066322275,0.0005337207,0.00011198844,0.00020620228],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003200609,0.00039501034,0.0007095306,0.00025783308,0.00012043472,0.00005590122,0.0001796545,0.00028999426,0.000023818538],"category_scores_gemma":[0.00019940648,0.00037411167,0.0001606979,0.00047062928,0.000032460033,0.0000017271066,0.0002505084,0.00012315271,0.0000103715565],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012264316,0.000028347655,0.000012835761,0.00230263,0.00033664776,0.0000011190086,0.00031513697,0.00010675317,0.022090172,0.000018401739,0.0018735186,0.9729022],"study_design_scores_gemma":[0.00008621129,0.00018817402,0.000065742955,0.00024786606,0.00020555909,0.000034779405,0.00013832843,0.0000019853228,0.007938204,0.0000035829273,0.9906249,0.0004646468],"about_ca_topic_score_codex":0.00009969242,"about_ca_topic_score_gemma":0.0001532332,"teacher_disagreement_score":0.9887514,"about_ca_system_score_codex":0.00003542644,"about_ca_system_score_gemma":0.00008442596,"threshold_uncertainty_score":0.9998711},"labels":[],"label_agreement":null},{"id":"W2136091231","doi":"10.1104/pp.004853","title":"Transgenic Plant Cells Lacking Mitochondrial Alternative Oxidase Have Increased Susceptibility to Mitochondria-Dependent and -Independent Pathways of Programmed Cell Death","year":2002,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"","keywords":"Programmed cell death; Mitochondrion; Alternative oxidase; Cell biology; Biology; Reactive oxygen species; Apoptosis; Nicotiana tabacum; Mitochondrial ROS; Biochemistry","score_opus":0.016309644944667308,"score_gpt":0.24557971613699783,"score_spread":0.22927007119233053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136091231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954726,0.00032684783,0.00247347,0.000017044185,0.00034619967,0.0006315172,0.0006037758,0.000019475074,0.00010907081],"genre_scores_gemma":[0.9973388,0.00020147428,0.0017098562,0.00006185559,0.00029127765,0.00006146876,0.00025437243,0.000027404907,0.000053528358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982184,0.00011273301,0.00037163423,0.00067187415,0.00017678722,0.0004485447],"domain_scores_gemma":[0.9991668,0.000057960133,0.00011057635,0.00038902686,0.000058548794,0.00021710595],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000981339,0.00029608217,0.00037498272,0.00007811808,0.000057540088,0.000015184874,0.00023956734,0.00019429163,0.00004169327],"category_scores_gemma":[0.00003284467,0.0002763187,0.00012178009,0.000051872954,0.000060166993,0.0000046646105,0.00013080999,0.00015659357,0.000008254899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000310772,0.00025004,0.00051188254,0.00007945582,0.00006890099,0.0000114182085,0.00045506438,0.00054236496,0.9972922,0.000013816567,0.00019283738,0.00027124424],"study_design_scores_gemma":[0.0015186291,0.00067686016,0.0023794542,0.00002166696,0.00004448059,0.000021193846,0.00013980003,0.0008901815,0.9933966,0.00005012937,0.000543089,0.00031794875],"about_ca_topic_score_codex":0.00019382032,"about_ca_topic_score_gemma":0.00026418536,"teacher_disagreement_score":0.0038956366,"about_ca_system_score_codex":0.000021032598,"about_ca_system_score_gemma":0.000023717237,"threshold_uncertainty_score":0.9999689},"labels":[],"label_agreement":null},{"id":"W2136405771","doi":"10.1158/1535-7163.mct-05-0229","title":"Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor","year":2005,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":141,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"AP site; Molecular biology; Melanoma; DNA-(apurinic or apyrimidinic site) lyase; Apoptosis; Transcription factor; Biology; DNA damage; Cancer research; Chemistry; Resveratrol; Base excision repair; DNA; Biochemistry; Gene","score_opus":0.012584265504455867,"score_gpt":0.30510517275107873,"score_spread":0.2925209072466229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136405771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99474907,0.00350178,0.00076956605,0.00036178634,0.000107256805,0.00043432563,0.000033246542,0.0000033741119,0.00003959061],"genre_scores_gemma":[0.9991776,0.0003121278,0.00005048893,0.0002829073,0.0000750609,0.00003934763,0.000010934828,0.00002543494,0.00002614301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855727,0.00025721808,0.000492692,0.00025960786,0.00025606685,0.00017713083],"domain_scores_gemma":[0.99899596,0.0000144318765,0.00022079394,0.0006749802,0.00006893263,0.00002487769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021900798,0.00016959298,0.00017603516,0.000057367735,0.000082049744,0.000020415288,0.00044227194,0.00013559006,0.000009725018],"category_scores_gemma":[0.000011102855,0.00011045434,0.0001238765,0.00017689756,0.00014438786,0.000011384902,0.0000939476,0.00016893918,1.8521307e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056629313,0.00012486358,0.0018871152,0.000027819327,0.00003911024,4.579193e-7,0.0009873816,0.0037314277,0.99075484,0.00015784742,0.0000037667162,0.0022287169],"study_design_scores_gemma":[0.00068947807,0.00012561526,0.02711344,0.00004631702,0.00005523325,0.000004962403,0.00032169698,0.0005918529,0.97030324,0.00015552535,0.00047502757,0.000117598545],"about_ca_topic_score_codex":0.00007164672,"about_ca_topic_score_gemma":0.00022765019,"teacher_disagreement_score":0.025226325,"about_ca_system_score_codex":0.000022224438,"about_ca_system_score_gemma":0.00007406,"threshold_uncertainty_score":0.45041975},"labels":[],"label_agreement":null},{"id":"W2137999973","doi":"10.1261/rna.033100.112","title":"Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Basic Energy Sciences; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Office of Science; National Institutes of Health; Eli Lilly and Company; U.S. Department of Energy","keywords":"Trans-activating crRNA; CRISPR; Biology; Genetics; RNA; CRISPR interference; Endonuclease; RNA silencing; Gene; DNA; Computational biology; Cas9; Nucleic acid; RNA interference","score_opus":0.011196783476383552,"score_gpt":0.29774073455151007,"score_spread":0.28654395107512654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137999973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9826495,0.014588346,0.0011763985,0.000018429184,0.00005870182,0.00008711709,0.00003367556,0.0000052212235,0.0013826162],"genre_scores_gemma":[0.99811435,0.0008085952,0.0006294869,0.00007170187,0.00010509622,0.000006569524,0.0000069442244,0.000015705002,0.00024157128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999457,0.00000960653,0.00015277174,0.000125803,0.00008475697,0.00017008925],"domain_scores_gemma":[0.99962527,0.000011894913,0.000055631688,0.0001709548,0.000069511385,0.000066735454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006710061,0.00009837469,0.00013391559,0.000025978943,0.00001584959,0.0000042654283,0.0000683643,0.00006824993,0.00002811338],"category_scores_gemma":[0.00006262089,0.00008876447,0.000041670923,0.00005929537,0.000041951964,0.000004243041,0.00006115191,0.00003373237,0.000001291256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031956715,0.00006438345,0.0050218906,0.0002814383,0.00005139526,4.4385104e-7,0.0003742166,0.000017789755,0.990505,0.00001280198,0.0018639878,0.0017746934],"study_design_scores_gemma":[0.0002049125,0.000083911014,0.014684657,0.000028902441,0.000034504446,0.00000877497,0.00009538018,0.00001856119,0.971254,0.0000081779135,0.013474989,0.000103246144],"about_ca_topic_score_codex":0.000044474138,"about_ca_topic_score_gemma":0.0000057978796,"teacher_disagreement_score":0.019251019,"about_ca_system_score_codex":0.0000020411758,"about_ca_system_score_gemma":0.000026474669,"threshold_uncertainty_score":0.36197102},"labels":[],"label_agreement":null},{"id":"W2138122869","doi":"10.1073/pnas.0403093101","title":"Mutator genes for suppression of gross chromosomal rearrangements identified by a genome-wide screening in <i>Saccharomyces cerevisiae</i>","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Colgate University; National Institutes of Health; Brandeis University; University of Toronto; University of Minnesota","keywords":"Biology; Genetics; Gene; Genome; Breakpoint; Telomere; Genome instability; Mutation; Chromosomal translocation; Saccharomyces cerevisiae; Chromatin; Chromosome; Mutant; DNA; DNA damage","score_opus":0.02001019010220111,"score_gpt":0.3202513698181449,"score_spread":0.3002411797159438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138122869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981505,0.001107442,0.000093235,0.00028961877,0.000014802224,0.00020015973,0.00004070307,0.0000020760199,0.00010146257],"genre_scores_gemma":[0.99708235,0.00011110795,0.002669805,0.000043373224,0.00004143208,0.000014948742,0.0000020742548,0.000004726877,0.000030185054],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999065,0.0000024053854,0.0002624773,0.0001959433,0.0003509787,0.000123192],"domain_scores_gemma":[0.99964607,0.000016194284,0.00019610884,0.0000097323855,0.00011123669,0.000020689262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044256958,0.000074727985,0.00011429604,0.000052086554,0.00005937472,0.000010181352,0.00039021633,0.00006577871,0.0000019881572],"category_scores_gemma":[0.00015560392,0.000057920504,0.00006236091,0.00019996136,0.00018669208,0.000019824429,0.00009932198,0.00004046004,6.43793e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021714894,0.000023983459,0.009623816,0.000095427975,0.000010887813,2.4061482e-9,0.000052252137,0.0009050726,0.98892134,0.000104885046,0.00012724532,0.00011338963],"study_design_scores_gemma":[0.00040029484,0.000052677846,0.032572784,0.000095968135,0.0000063529433,0.0000016491136,0.00009468677,0.00008196773,0.96544826,0.0008924934,0.00029131531,0.00006157167],"about_ca_topic_score_codex":0.0000057209254,"about_ca_topic_score_gemma":1.692011e-7,"teacher_disagreement_score":0.023473084,"about_ca_system_score_codex":0.0000067827464,"about_ca_system_score_gemma":0.00001707767,"threshold_uncertainty_score":0.23619296},"labels":[],"label_agreement":null},{"id":"W2138164217","doi":"10.15252/msb.20145216","title":"Measuring error rates in genomic perturbation screens: gold standards for human functional genomics","year":2014,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":464,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Princess Margaret Cancer Centre; University Health Network; Ontario Institute for Cancer Research; University of Toronto","funders":"Ontario Institute for Cancer Research; Ontario Ministry of Research and Innovation; Canadian Institute for Advanced Research","keywords":"CRISPR; Biology; Computational biology; Functional genomics; RNA interference; Gene; Genomics; Genetics; Genome; RNA","score_opus":0.02152405074075081,"score_gpt":0.30640752189763765,"score_spread":0.28488347115688684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138164217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6248495,0.0018908161,0.3721692,0.000034656932,0.0003215262,0.00034851424,0.000044474426,0.000014641894,0.0003266914],"genre_scores_gemma":[0.9981691,0.000018931549,0.00057986804,0.00008408779,0.00035455351,0.00012950432,0.00038832639,0.000039877632,0.00023570572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874836,0.00010803072,0.00032637545,0.00042139806,0.000084201325,0.00031165],"domain_scores_gemma":[0.9994263,0.000016937214,0.000078270845,0.0002858821,0.00013421832,0.00005837789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000617057,0.00019055666,0.00023322704,0.000102523765,0.00006018403,0.000025137824,0.00014425028,0.0002329716,0.0000031659386],"category_scores_gemma":[0.00012496847,0.00019611183,0.00009953742,0.000055645713,0.000041257565,0.0000023330201,0.00006027734,0.000076316435,0.0000027116093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004526802,0.000014493505,0.001429962,0.000055727607,0.000044040687,6.9757857e-7,0.000019573004,0.011493815,0.9838194,0.0024000728,0.00016843587,0.00050846644],"study_design_scores_gemma":[0.0050151483,0.0015882754,0.013383841,0.00011300565,0.00007977304,0.00007975383,0.00021221879,0.030090673,0.71739054,0.0012722797,0.22937419,0.0014003133],"about_ca_topic_score_codex":0.000054811466,"about_ca_topic_score_gemma":0.000075365635,"teacher_disagreement_score":0.37331966,"about_ca_system_score_codex":0.00007996051,"about_ca_system_score_gemma":0.000063663516,"threshold_uncertainty_score":0.7997208},"labels":[],"label_agreement":null},{"id":"W2138743196","doi":"10.1093/nar/gkl631","title":"Zfp206 regulates ES cell gene expression and differentiation","year":2006,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene; Gene expression; Transcription factor; Cellular differentiation; Gene isoform; Molecular biology; Embryonic stem cell; Cell biology; Regulation of gene expression; Zinc finger; Genetics; Transcription (linguistics); Embryo","score_opus":0.012268491808674752,"score_gpt":0.3092244585708652,"score_spread":0.2969559667621905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138743196","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944258,0.0016871742,0.0023410204,0.000056781882,0.00004117483,0.00011191994,0.0000048892284,0.000013918235,0.0013173535],"genre_scores_gemma":[0.9959973,0.00023992686,0.0017058455,0.000007268633,0.00025311823,0.000012609109,0.00007019688,0.000021266944,0.0016924297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990909,0.00005095255,0.000110811925,0.00027012292,0.00021148012,0.00026569996],"domain_scores_gemma":[0.9995957,0.000014470366,0.000015588488,0.00024124098,0.00007444695,0.000058562997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020138362,0.000090591035,0.0000732914,0.00006751427,0.00012349663,0.000045696703,0.00011172253,0.00011908466,0.000031605112],"category_scores_gemma":[0.000024466955,0.00008273761,0.000028503204,0.00007843059,0.00006801488,0.0000032191067,0.00016356404,0.00010743545,0.000009700047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018609846,0.000029544612,0.00427906,0.000022077647,0.0000032279,0.0000011287507,0.000022150916,0.000077918434,0.9918662,0.0000304363,0.002679124,0.00097054814],"study_design_scores_gemma":[0.0002874789,0.000088865396,0.030811075,0.000008680604,0.0000026389546,0.0000034546003,0.000037378282,0.00044342832,0.9625442,0.00017230267,0.005503981,0.000096496944],"about_ca_topic_score_codex":0.00002398038,"about_ca_topic_score_gemma":0.000007590417,"teacher_disagreement_score":0.029321954,"about_ca_system_score_codex":0.000009069481,"about_ca_system_score_gemma":0.000013789805,"threshold_uncertainty_score":0.3373942},"labels":[],"label_agreement":null},{"id":"W2138748203","doi":"10.1186/gm442","title":"The Human Genome Organisation: towards next-generation ethics","year":2013,"lang":"en","type":"article","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Intellectual property; Confidentiality; Autonomy; Research ethics; Human rights; Informed consent; Law; Political science; Bioethics; Harmonization; Sociology; Engineering ethics; Medicine","score_opus":0.043837814799873406,"score_gpt":0.3243243370123589,"score_spread":0.2804865222124855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138748203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9553839,0.008576603,0.021050293,0.010226487,0.0006275994,0.0004821029,0.0000039709903,0.000039110524,0.0036099479],"genre_scores_gemma":[0.9933908,0.0007449696,0.00025625748,0.00078094756,0.002366245,0.000038147464,0.00023916374,0.00002399314,0.0021594903],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991084,0.000041440522,0.00022234643,0.00021947386,0.0001890322,0.00021932035],"domain_scores_gemma":[0.99935544,0.00001343098,0.000046002675,0.00037321652,0.00012346958,0.00008845874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037504456,0.00013331846,0.00010533567,0.000026256763,0.00031372908,0.00003986018,0.00020611363,0.00012815159,0.0003401297],"category_scores_gemma":[0.00011054351,0.000091797214,0.00003223732,0.000071295566,0.00011427108,0.000003605752,0.00006843492,0.00016460635,0.00006318692],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000011693527,0.000005055963,0.000039349157,0.000008216059,0.00002106362,4.6909136e-7,0.00044020725,0.00013108997,0.99626744,0.00012607164,0.0011257713,0.001834099],"study_design_scores_gemma":[0.0012673321,0.00088354596,0.058181945,0.000015796948,0.00007137533,0.000050464132,0.0016263477,0.000500098,0.1742969,0.0005776463,0.761922,0.0006065129],"about_ca_topic_score_codex":0.000069270885,"about_ca_topic_score_gemma":0.000041232874,"teacher_disagreement_score":0.8219705,"about_ca_system_score_codex":0.000018894641,"about_ca_system_score_gemma":0.00004703543,"threshold_uncertainty_score":0.37433815},"labels":[],"label_agreement":null},{"id":"W2138967777","doi":"10.5376/cge.2014.02.0002","title":"The Present Situation and Prospection for Gene Therapy of Breast Cancer","year":2014,"lang":"en","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Prospection; Breast cancer; Oncology; Cancer; Medicine; Biology; Geography; Internal medicine; Archaeology","score_opus":0.008786198310913634,"score_gpt":0.302605037026425,"score_spread":0.29381883871551134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138967777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91099876,0.056166712,0.031631544,0.0004431009,0.00026895653,0.00039412786,0.000068265275,0.0000052798882,0.00002326738],"genre_scores_gemma":[0.8557001,0.14264806,0.00085231056,0.00004401591,0.0004886162,0.0001277278,0.000012028711,0.000022516186,0.00010464727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928147,0.000018106508,0.00018449691,0.0002409003,0.00008866814,0.00018633594],"domain_scores_gemma":[0.9994808,0.000022124175,0.000074978125,0.0002066744,0.00014988387,0.00006552591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014349214,0.0001308127,0.00011433146,0.000018543358,0.00013807915,0.000029800101,0.00008353388,0.00008401413,0.0000021810683],"category_scores_gemma":[0.000011359551,0.00010369681,0.000037714897,0.000043736098,0.00010212053,0.0000014375596,0.000049180027,0.000035344034,6.933301e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119735734,0.00002560132,0.02041952,0.000060321745,0.00010187239,3.6109512e-8,0.00016584128,0.0077199475,0.6052453,0.00012349406,0.0003758952,0.36564243],"study_design_scores_gemma":[0.00093136675,0.00038468523,0.16294524,0.000017959666,0.00004151295,0.000005622684,0.00004537104,0.012767621,0.72563654,0.0005354796,0.096439816,0.00024878187],"about_ca_topic_score_codex":0.000044167005,"about_ca_topic_score_gemma":0.00012007041,"teacher_disagreement_score":0.36539364,"about_ca_system_score_codex":0.0000074134837,"about_ca_system_score_gemma":0.00003568809,"threshold_uncertainty_score":0.4228633},"labels":[],"label_agreement":null},{"id":"W2139479645","doi":"10.1038/sj.emboj.7600026","title":"Drosophila Cup is an eIF4E‐binding protein that functions in Smaug‐mediated translational repression","year":2003,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Psychological repression; EIF4E; Cell biology; Drosophila (subgenus); Genetics; Translation (biology); Gene; Gene expression; Messenger RNA","score_opus":0.020203855287560326,"score_gpt":0.2925894663692768,"score_spread":0.2723856110817165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139479645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928258,0.0005727565,0.0051103416,0.00037495972,0.00017427612,0.000120239,0.000007413277,0.000006556142,0.0008076473],"genre_scores_gemma":[0.99864024,0.000064203545,0.0004153774,0.00006489642,0.00019122301,0.000009359507,0.000023709377,0.000015835036,0.0005751333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992555,0.00009069973,0.00016796277,0.00015422031,0.000143052,0.00018856366],"domain_scores_gemma":[0.99964535,0.0000094540965,0.000051626597,0.00018637854,0.000029607358,0.00007758581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038944278,0.00010312182,0.00007879118,0.00005212573,0.00016436687,0.000038015365,0.00012151922,0.00007417748,0.000112845286],"category_scores_gemma":[0.000045261957,0.00007675133,0.00006227822,0.000088088964,0.000026344273,0.000008114123,0.000013153601,0.00023336532,0.0000074678765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044283053,0.000050631617,0.0036857433,0.0000045317147,0.000025031042,0.000006600288,0.00033916222,0.0027056609,0.99190414,0.000047459624,0.0004580027,0.0007287378],"study_design_scores_gemma":[0.0025237743,0.00034271114,0.022322144,0.00013410878,0.00004660881,0.00084034185,0.00073475234,0.0019395292,0.93935037,0.00242895,0.028764986,0.000571706],"about_ca_topic_score_codex":0.0000029126943,"about_ca_topic_score_gemma":0.000009605164,"teacher_disagreement_score":0.05255377,"about_ca_system_score_codex":0.000009757573,"about_ca_system_score_gemma":0.000052963176,"threshold_uncertainty_score":0.31298283},"labels":[],"label_agreement":null},{"id":"W2139753008","doi":"10.1073/pnas.0505474102","title":"Gene targeting using a promoterless gene trap vector (“targeted trapping”) is an efficient method to mutate a large fraction of genes","year":2005,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsche Forschungsgemeinschaft; Damon Runyon Cancer Research Foundation; University of Toronto; Howard Hughes Medical Institute","keywords":"Gene; Biology; Gene targeting; Homologous recombination; Genetics; Gene delivery; Genome; Computational biology; Transfection","score_opus":0.03029263105871084,"score_gpt":0.3608025747592533,"score_spread":0.3305099437005425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139753008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99346036,0.0004464977,0.005475291,0.0003277825,0.000015913538,0.00020006935,0.000034143508,0.000005541558,0.000034383524],"genre_scores_gemma":[0.904529,0.000015451204,0.09517949,0.00010847296,0.0001453662,0.000006381306,9.189136e-7,0.0000074483683,0.000007482617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986621,0.000011085438,0.00034062503,0.00029923877,0.0004958796,0.00019107478],"domain_scores_gemma":[0.99940753,0.000012004336,0.0002571638,0.000015340442,0.0002558204,0.000052123836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011603127,0.000113236056,0.00016005718,0.00012939333,0.00011663831,0.00001264205,0.00037048513,0.00009131925,0.0000062896024],"category_scores_gemma":[0.00009822479,0.000090091766,0.00008613495,0.00040836388,0.00009389013,0.000019331246,0.000085356034,0.00007206635,1.8062815e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019229343,0.00006451211,0.00031203078,0.000037917496,0.00001749269,3.6091599e-9,0.00037101566,0.023505883,0.97445416,0.00004892512,0.000019308305,0.0011494996],"study_design_scores_gemma":[0.0001573323,0.000082534796,0.0040347097,0.000026092332,0.00001541918,0.0000072836997,0.00018364999,0.047595873,0.94748443,0.00009515177,0.00021815003,0.00009938481],"about_ca_topic_score_codex":0.0000069723596,"about_ca_topic_score_gemma":1.1048626e-7,"teacher_disagreement_score":0.0897042,"about_ca_system_score_codex":0.000018736928,"about_ca_system_score_gemma":0.00003376768,"threshold_uncertainty_score":0.36738354},"labels":[],"label_agreement":null},{"id":"W2139866374","doi":"10.1186/gm549","title":"A genome scale overexpression screen to reveal drug activity in human cells","year":2014,"lang":"en","type":"article","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute","keywords":"Human genome; Computational biology; Human genetics; ORFS; Drug; Drug discovery; Drug action; Drug resistance; Gene; Genome; Biology; Transcription factor; Genetics; Bioinformatics; Pharmacology","score_opus":0.005995815649893305,"score_gpt":0.2773962285039243,"score_spread":0.271400412854031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139866374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988015,0.00027989745,0.008710072,0.00033976862,0.00008602768,0.00022574056,0.00000880466,0.000013696515,0.0023210093],"genre_scores_gemma":[0.9966971,0.00002587539,0.00053765834,0.00027562503,0.00072550867,0.000015053621,0.00005770945,0.000024661462,0.0016407507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989592,0.000046637957,0.00018738082,0.0003636391,0.00014883127,0.00029434328],"domain_scores_gemma":[0.99934703,0.000009193216,0.000036606983,0.0004078288,0.000026389422,0.00017292872],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003566883,0.00016113423,0.00021697753,0.00009550591,0.000050378738,0.000005930405,0.000200325,0.00007983122,0.000058084283],"category_scores_gemma":[0.000028744847,0.00014392569,0.000036987392,0.00011712544,0.00004087216,0.0000020992686,0.00014732587,0.00010875377,0.000016344415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029037681,0.000023675202,0.0004311576,0.000024592211,0.0000057176667,0.0000013222817,0.00022040897,0.00077226677,0.99708307,0.0000024695062,0.000531064,0.0008752266],"study_design_scores_gemma":[0.0012629919,0.0005090926,0.12361395,0.00009328355,0.000013015138,0.0000049762643,0.000073128904,0.000064700056,0.81090754,0.000034767832,0.06309625,0.00032632888],"about_ca_topic_score_codex":0.0001425025,"about_ca_topic_score_gemma":0.00009363775,"teacher_disagreement_score":0.18617554,"about_ca_system_score_codex":0.000022082397,"about_ca_system_score_gemma":0.0000114148825,"threshold_uncertainty_score":0.5869119},"labels":[],"label_agreement":null},{"id":"W2140035719","doi":"10.4067/s0717-34582004000300004","title":"Controlling proteolytic degradation of the methionine enriched MB-1Trp protein","year":2004,"lang":"en","type":"article","venue":"Scientific Electronic Library Online (Scientific Electronic Library Online)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Proteolysis; Protease; Biochemistry; Mutant; Proteolytic enzymes; Amino acid; Protein degradation; Peptide; Protein folding; Methionine; Biology; Chemistry; Gene; Enzyme","score_opus":0.0061599400408653615,"score_gpt":0.24459466479535336,"score_spread":0.238434724754488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140035719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778843,0.009352809,0.0045960387,0.0038415238,0.0012044316,0.0022910063,0.00031606053,0.00026325753,0.00025059894],"genre_scores_gemma":[0.9519265,0.00020540212,0.0043321834,0.00026179198,0.0005554127,0.000109613975,0.004171997,0.0001794994,0.03825757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9936629,0.00028270102,0.0012059412,0.0018302641,0.0009674153,0.0020507753],"domain_scores_gemma":[0.9969697,0.00004717767,0.0005341552,0.0020152687,0.00015101567,0.00028268868],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008510478,0.00070695626,0.00060266175,0.00046216202,0.0007892154,0.0005748615,0.002114844,0.0003897735,0.00023777485],"category_scores_gemma":[0.00017741078,0.00057202775,0.00056811946,0.0027484288,0.00085274654,0.0003300527,0.00068826013,0.0010561438,0.000017206445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023967747,0.00092098437,0.00029991695,0.00015083195,0.00020237245,0.0000032312182,0.00012787044,0.0049975743,0.9738032,0.015710196,0.0014601686,0.002083978],"study_design_scores_gemma":[0.0026161463,0.00069855305,0.0004681383,0.0001751441,0.00011041443,0.000048165286,0.00013209292,0.0027980958,0.9138521,0.01405324,0.064231,0.00081688486],"about_ca_topic_score_codex":0.000013277194,"about_ca_topic_score_gemma":0.00011954652,"teacher_disagreement_score":0.062770836,"about_ca_system_score_codex":0.00012714943,"about_ca_system_score_gemma":0.0052898363,"threshold_uncertainty_score":0.9996731},"labels":[],"label_agreement":null},{"id":"W2140306886","doi":"10.1186/1472-6750-8-88","title":"Homologous recombination-mediated cloning and manipulation of genomic DNA regions using Gateway and recombineering systems","year":2008,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Recombineering; Biology; Genetics; Gene; Computational biology; Homologous recombination; Selectable marker; Coding region; genomic DNA; Transformation (genetics)","score_opus":0.019192494240109437,"score_gpt":0.25404006251122585,"score_spread":0.2348475682711164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140306886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94720167,0.0027891127,0.049632344,0.000039704937,0.0001340143,0.00013971046,0.000003911969,0.000036500827,0.000023033886],"genre_scores_gemma":[0.9929051,0.0010600339,0.0059088203,0.0000049050623,0.000026267726,0.000006352438,0.000026239346,0.000018518327,0.000043794185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993397,0.000020150812,0.00020687452,0.00024038045,0.000037523536,0.00015536918],"domain_scores_gemma":[0.99964744,0.000017873976,0.00008035986,0.00019088667,0.000030471292,0.000032994954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083217776,0.000112203255,0.00015860221,0.00013875525,0.00007418918,0.000005283646,0.00006809654,0.0003273152,0.0000012621438],"category_scores_gemma":[0.000057187674,0.00012456567,0.000022510243,0.000077152145,0.00012138358,0.000003271661,0.00009061013,0.000082948456,7.213691e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000947837,0.000011258967,0.004716924,0.00004748636,0.000019042847,0.000002745993,0.00002889036,0.0013483694,0.9932103,0.00041857077,0.0000119888555,0.00017491158],"study_design_scores_gemma":[0.0017239694,0.00059898477,0.061936807,0.00008652231,0.00006089335,0.0023549167,0.00034251425,0.051823236,0.87884223,0.00023691263,0.0013540887,0.00063892984],"about_ca_topic_score_codex":0.00004829339,"about_ca_topic_score_gemma":0.000015686284,"teacher_disagreement_score":0.1143681,"about_ca_system_score_codex":0.00001251836,"about_ca_system_score_gemma":0.000022597807,"threshold_uncertainty_score":0.5079641},"labels":[],"label_agreement":null},{"id":"W2141795153","doi":"10.1007/978-3-7091-6232-3_18","title":"Gene Therapy for Vasospasm","year":2001,"lang":"en","type":"review","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Genetic enhancement; Gene; Gene expression; Medicine; Transcription (linguistics); Biology; Genetics","score_opus":0.031788959027308133,"score_gpt":0.3798449742061438,"score_spread":0.34805601517883566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141795153","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000024573403,0.967331,0.030333256,0.0000050665594,0.00020813198,0.00059436396,0.00002804325,0.000016371718,0.001481293],"genre_scores_gemma":[0.000002517309,0.98974025,0.0029046617,0.000052531595,0.00076160755,0.00021859705,0.0005195775,0.000066366614,0.0057338714],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991753,0.000012092404,0.00021219789,0.00033418127,0.000048864662,0.00021733632],"domain_scores_gemma":[0.9994896,0.000011936547,0.000048593683,0.00036506297,0.000029355911,0.000055423276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076313314,0.00026138104,0.00045957952,0.000035015833,0.000028434666,0.000015535266,0.00019284907,0.00029831764,0.00004258476],"category_scores_gemma":[0.00001265378,0.00020320542,0.00044205034,0.0000631984,0.000012003741,3.266649e-7,0.000039899525,0.000057186982,0.000012688996],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000028133413,0.000013868886,2.4089647e-7,0.00067615655,0.00011909771,5.9680286e-7,0.0000012299216,0.000003881979,0.0002344943,0.000010770234,0.0036455395,0.9952913],"study_design_scores_gemma":[0.00017264609,0.000112943635,2.2933112e-7,0.00014720074,0.00006968996,0.000028679193,0.0000012957627,0.0000022847462,0.0020357287,0.0000065773183,0.99715704,0.00026567563],"about_ca_topic_score_codex":0.0000021946148,"about_ca_topic_score_gemma":0.0000025121635,"teacher_disagreement_score":0.99502563,"about_ca_system_score_codex":0.0000068771765,"about_ca_system_score_gemma":0.00006537516,"threshold_uncertainty_score":0.8286477},"labels":[],"label_agreement":null},{"id":"W2142953616","doi":"10.1016/j.celrep.2015.09.009","title":"A Scalable Genome-Editing-Based Approach for Mapping Multiprotein Complexes in Human Cells","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Computational biology; Chromatin; Biology; Genome editing; Effector; Proteomics; CRISPR; Genome; Multiprotein complex; Cas9; Robustness (evolution); DNA; Gene; Cell biology; Genetics","score_opus":0.02142200617300855,"score_gpt":0.2730510858315443,"score_spread":0.25162907965853576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142953616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7236892,0.0005985419,0.272096,0.000010078961,0.00013185818,0.0006264561,0.0000061827686,0.000022674543,0.0028190147],"genre_scores_gemma":[0.97487164,0.0000016989311,0.023819517,0.000037554335,0.00020392783,0.000113706956,0.00026998995,0.00002958248,0.0006524058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894375,0.000015276186,0.00029822774,0.00036977686,0.00009927154,0.00027371783],"domain_scores_gemma":[0.9994066,0.0000049325217,0.00009705353,0.00031908468,0.00006598717,0.00010638925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036111794,0.00013898501,0.00015457613,0.000059604987,0.00004379789,0.000021396616,0.000082602746,0.000104023704,0.000003911395],"category_scores_gemma":[0.00004216248,0.00014931259,0.000068289664,0.00007015676,0.000028068376,0.0000019267459,0.000048196707,0.000061361694,8.022636e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073234223,0.00007358808,0.0015618174,0.00009243732,0.000004942235,0.000017209397,0.000054212032,0.053627305,0.9438351,0.0000010157096,0.00064700464,0.00007803551],"study_design_scores_gemma":[0.0006263361,0.00009452779,0.0003348094,0.000011156478,0.000005743466,0.000012685594,0.00014521631,0.0056048236,0.96546376,0.000022498427,0.027471611,0.00020685664],"about_ca_topic_score_codex":0.000039987746,"about_ca_topic_score_gemma":0.000011292954,"teacher_disagreement_score":0.25118244,"about_ca_system_score_codex":0.000021869562,"about_ca_system_score_gemma":0.000055890596,"threshold_uncertainty_score":0.6088791},"labels":[],"label_agreement":null},{"id":"W2143554177","doi":"10.1371/journal.pone.0040913","title":"Cleavage of Phage DNA by the Streptococcus thermophilus CRISPR3-Cas System","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Streptococcus thermophilus; Trans-activating crRNA; Plasmid; Biology; Palindrome; Genome; DNA; Genetics; Bacteriophage; Rolling circle replication; Nucleic acid; Microbiology; Gene; Bacteria; DNA replication; Escherichia coli","score_opus":0.016694061819592418,"score_gpt":0.2549414086113949,"score_spread":0.23824734679180248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143554177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990936,0.0042609023,0.0009828785,0.000056362107,0.00007600129,0.00025819635,0.00005184827,0.000020130914,0.00335771],"genre_scores_gemma":[0.9990144,0.000066520166,0.00014687685,0.000038440066,0.00028377757,0.000032696476,0.000028046075,0.000024682624,0.00036460266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927396,0.000033431254,0.00016621202,0.00014041142,0.00014934421,0.00023664245],"domain_scores_gemma":[0.99943244,0.000013153497,0.000055895158,0.0003977238,0.000032628985,0.0000681438],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015224365,0.000116667354,0.0001399536,0.000013823571,0.000042213876,0.000007837212,0.00018267949,0.000082765924,0.000015630523],"category_scores_gemma":[0.00002625029,0.00008840273,0.000059605267,0.000049967777,0.000039323353,0.000002494881,0.00007398435,0.00006826773,0.00001704733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000127968115,0.00023283996,0.0016230448,0.0001080442,0.00014683638,4.902666e-7,0.00011167785,0.000004571512,0.9955523,0.000044213655,0.0017538008,0.000409358],"study_design_scores_gemma":[0.000202558,0.00008224855,0.0022939534,0.000034196542,0.000072925635,0.0000034894658,0.0001946101,0.0000464086,0.9958106,0.0000016280857,0.0011497424,0.00010763776],"about_ca_topic_score_codex":0.000008588082,"about_ca_topic_score_gemma":0.0000024858439,"teacher_disagreement_score":0.008078387,"about_ca_system_score_codex":0.000009734794,"about_ca_system_score_gemma":0.000009130197,"threshold_uncertainty_score":0.3604959},"labels":[],"label_agreement":null},{"id":"W2143611818","doi":"10.1080/14636778.2010.507485","title":"Personal genomics and individual identities: motivations and moral imperatives of early users","year":2010,"lang":"en","type":"article","venue":"New Genetics and Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Human Genome Research Institute; Case Western Reserve University","keywords":"Personal genomics; Variety (cybernetics); Skepticism; Genomics; Biomedicine; Psychology; Data science; Genomic medicine; Optimism; Internet privacy; Knowledge management; Genome; Social psychology; Computer science; Biology; Epistemology; Genetics; Computational biology; Artificial intelligence","score_opus":0.010701111615499179,"score_gpt":0.2663685938121081,"score_spread":0.2556674821966089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143611818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974173,0.0012653401,0.001060119,0.000044412966,0.00005789198,0.000066529676,0.000036618287,0.0000031471616,0.00004868495],"genre_scores_gemma":[0.99109805,0.0017065924,0.0068453755,0.00005297055,0.000111072884,0.0000018820924,0.00001700084,0.000010889897,0.0001561883],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995553,0.0000054794937,0.00010061374,0.0001666635,0.000062943625,0.000109008986],"domain_scores_gemma":[0.9997694,0.000008528279,0.000026632197,0.00007944167,0.00003043394,0.000085556356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005999642,0.00009300459,0.00008687988,0.000011588607,0.0000732368,0.000041538315,0.00004444056,0.00010894353,0.0000047147205],"category_scores_gemma":[0.00000900627,0.00009550557,0.000038043643,0.000024749854,0.00014701723,0.000003330172,0.00008971008,0.00008342697,7.167065e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000043544833,0.000011676106,0.08609259,0.000026731837,0.00009090927,1.510375e-7,0.0063594915,0.000027290533,0.9044704,0.00023482638,0.0005325959,0.0021489826],"study_design_scores_gemma":[0.001076986,0.00031347017,0.86681974,0.000007950698,0.000070496106,0.00001758315,0.0024866303,0.001250381,0.1248439,0.00035635766,0.00243686,0.00031963413],"about_ca_topic_score_codex":0.000018902885,"about_ca_topic_score_gemma":0.00001810427,"teacher_disagreement_score":0.78072715,"about_ca_system_score_codex":0.000001435444,"about_ca_system_score_gemma":0.00004153518,"threshold_uncertainty_score":0.38946044},"labels":[],"label_agreement":null},{"id":"W2146746820","doi":"10.1534/genetics.105.050229","title":"Rates of Recombination in the Ribosomal DNA of Apomictically Propagated <i>Daphnia obtusa</i> Lines","year":2006,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"National Institute of General Medical Sciences","keywords":"Biology; Recombination; Ribosomal DNA; Genetics; Concerted evolution; Ribosomal RNA; Ploidy; Gene; Phylogenetics","score_opus":0.0072245004123843585,"score_gpt":0.2804580395296238,"score_spread":0.2732335391172394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146746820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99618125,0.00095518166,0.002052799,0.000099646,0.00006598896,0.00016472807,0.000010208304,0.0000035874816,0.0004665852],"genre_scores_gemma":[0.99775636,0.0001512114,0.0018585464,0.000024436005,0.00008027363,0.0000089476525,0.0000624566,0.000011298992,0.00004648811],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929714,0.00003998034,0.00028906288,0.00013759892,0.00010380112,0.00013238742],"domain_scores_gemma":[0.99958897,0.000017785515,0.00007082493,0.00021537625,0.00009328855,0.000013750787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015694676,0.00009265721,0.00011134727,0.00003776423,0.000014010423,0.0000061578253,0.00015992796,0.000087088985,0.0000032631085],"category_scores_gemma":[0.00004046953,0.00007532289,0.00004600757,0.00013327402,0.00005505218,0.0000011666315,0.00003609737,0.00004804018,7.818476e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018762095,0.000093470335,0.010332579,0.000035244506,0.000008551884,6.1785596e-7,0.00003834464,0.0026338857,0.9856896,0.00011376926,0.00029574463,0.00073947397],"study_design_scores_gemma":[0.00037733928,0.00018003101,0.04943472,0.000012633126,0.00001290997,0.000004850985,0.000041222414,0.00058349315,0.9476056,0.00025794478,0.0014018343,0.00008738625],"about_ca_topic_score_codex":0.000017739816,"about_ca_topic_score_gemma":0.00008410445,"teacher_disagreement_score":0.03910214,"about_ca_system_score_codex":0.000003388857,"about_ca_system_score_gemma":0.00002857782,"threshold_uncertainty_score":0.3071578},"labels":[],"label_agreement":null},{"id":"W2146753265","doi":"10.1038/nm.2459","title":"Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155","year":2011,"lang":"en","type":"article","venue":"Nature Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institutes of Health","keywords":"Oncomir; microRNA; miR-155; Biology; Cancer research; Gene knockdown; Suppressor; DNA damage; DNA repair; Psychological repression; Epigenetics; Cell cycle; Cell biology; Genetics; Gene; DNA; Gene expression","score_opus":0.0073529919914732365,"score_gpt":0.2853218310364342,"score_spread":0.277968839044961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146753265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95302194,0.026271084,0.008030072,0.00081098406,0.0011929496,0.00042461164,0.000028011571,0.00005376392,0.010166571],"genre_scores_gemma":[0.99428195,0.00017736973,0.001922862,0.0016359544,0.0010191227,0.000020018182,0.0000646958,0.000038933416,0.00083906675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998743,0.000033439064,0.00027481088,0.00039552798,0.00019396184,0.00035929086],"domain_scores_gemma":[0.9991509,0.000020709549,0.0000579037,0.00046872854,0.00011433893,0.00018745763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021184773,0.00023092503,0.0002683173,0.00005851971,0.00004490484,0.0000054477214,0.00030765592,0.00031852126,0.0003326956],"category_scores_gemma":[0.0002755111,0.00018348548,0.000095562995,0.00009467745,0.00013653381,0.0000017430683,0.00007821031,0.00036179685,0.000023473425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011643033,0.000040440136,0.00050051825,0.000020732985,0.00007445697,0.000032975502,0.000097997676,0.000004702981,0.99186504,0.0001326687,0.0058010784,0.0013129557],"study_design_scores_gemma":[0.0016378558,0.00058730977,0.013785769,0.000037239122,0.000077272176,0.00012612624,0.00004795764,0.000024826388,0.8797612,0.00011213,0.103555664,0.00024660298],"about_ca_topic_score_codex":0.000014545833,"about_ca_topic_score_gemma":0.000018407152,"teacher_disagreement_score":0.1121038,"about_ca_system_score_codex":0.000010275633,"about_ca_system_score_gemma":0.000043386102,"threshold_uncertainty_score":0.74823207},"labels":[],"label_agreement":null},{"id":"W2147321255","doi":"10.1002/bies.201500083","title":"When natural selection gives gene function the cold shoulder","year":2015,"lang":"en","type":"review","venue":"BioEssays","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Natural selection; Biology; Gene; Selection (genetic algorithm); Genome; Adaptation (eye); Function (biology); Evolutionary biology; Negative selection; Genetics; Trait; Genetic Fitness; Computational biology; Computer science; Neuroscience","score_opus":0.02721184739845854,"score_gpt":0.3385374864523148,"score_spread":0.31132563905385624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147321255","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000017153625,0.9928545,0.0052288007,0.000025991836,0.0009985546,0.00038985795,0.00002399477,0.000029559926,0.00043162325],"genre_scores_gemma":[0.00048883515,0.9938584,0.00027408017,0.000055284294,0.0014336291,0.000096718984,0.00037586634,0.00005823489,0.0033589562],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99893266,0.00008014001,0.00023527972,0.00036885645,0.0001531405,0.0002299022],"domain_scores_gemma":[0.9993956,0.000011356499,0.00010045261,0.00034222793,0.00008815354,0.00006221805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021628579,0.00030219715,0.0003735375,0.000049545077,0.000085401174,0.00004475729,0.00023164065,0.00035790898,0.00001820119],"category_scores_gemma":[0.000029861227,0.00019885175,0.00024386954,0.0001141633,0.000042990156,0.000002207223,0.0001034645,0.00023009481,0.000022266937],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026601765,0.000048931397,0.000009909602,0.0020743404,0.00061199884,0.0000025109744,0.0000536274,0.00007321119,0.012344775,0.0001239213,0.10571707,0.8789131],"study_design_scores_gemma":[0.000098585915,0.00008602207,0.0000031170437,0.00015349261,0.00031345597,0.000044442007,0.000011623699,0.000019614554,0.0011340425,0.000013017907,0.99786174,0.0002608637],"about_ca_topic_score_codex":0.00000849699,"about_ca_topic_score_gemma":0.00001716996,"teacher_disagreement_score":0.8921447,"about_ca_system_score_codex":0.00003460814,"about_ca_system_score_gemma":0.00013545467,"threshold_uncertainty_score":0.8108939},"labels":[],"label_agreement":null},{"id":"W2148508291","doi":"10.1093/bfgp/elm022","title":"EUCOMM the European Conditional Mouse Mutagenesis Program","year":2007,"lang":"en","type":"article","venue":"Briefings in Functional Genomics and Proteomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Biology; Mutagenesis; Mutant; Cre recombinase; Genetics; Gene targeting; Conditional gene knockout; Embryonic stem cell; Gene; Gene knockin; Insertional mutagenesis; Computational biology; Recombinase; Mutation; Transgene; Phenotype; Genetically modified mouse; Recombination","score_opus":0.008958210877697763,"score_gpt":0.258466564914948,"score_spread":0.24950835403725025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148508291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94425875,0.00049571355,0.05271,0.0003714785,0.0001030835,0.0004006547,0.000022673548,0.00001863344,0.0016189907],"genre_scores_gemma":[0.9891688,0.0002074595,0.008525663,0.0008891259,0.00050200225,0.000038713653,0.00018154884,0.000036027923,0.0004506216],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999214,0.000028871757,0.00020852209,0.00024617722,0.00008630846,0.0002161511],"domain_scores_gemma":[0.9996734,0.000021098227,0.00004749177,0.00015695878,0.000042178264,0.000058833204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006900855,0.00012888752,0.00007869547,0.000040676045,0.0001273504,0.000044625824,0.000105824685,0.000069462534,0.000008391457],"category_scores_gemma":[0.000038242222,0.00011520392,0.00004805526,0.0000636927,0.00008699062,0.000003055038,0.000106182546,0.00012063416,0.0000044635076],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002788328,0.00016594063,0.0072048726,0.000039801413,0.000097570104,0.000013109007,0.00018120506,0.0075564794,0.9337903,0.0023232237,0.0028629652,0.045485657],"study_design_scores_gemma":[0.0016532651,0.00030559272,0.25595033,0.00001377528,0.000027550528,0.00023538267,0.00016801083,0.0009386784,0.2540911,0.0011178522,0.48484614,0.00065229664],"about_ca_topic_score_codex":0.00002497825,"about_ca_topic_score_gemma":0.000050915303,"teacher_disagreement_score":0.67969924,"about_ca_system_score_codex":0.000018801122,"about_ca_system_score_gemma":0.00003441905,"threshold_uncertainty_score":0.46978796},"labels":[],"label_agreement":null},{"id":"W2149672766","doi":"10.4269/ajtmh.2008.79.312","title":"Ethical, Social, and Cultural Considerations for Site Selection for Research with Genetically Modified Mosquitoes","year":2008,"lang":"en","type":"article","venue":"American Journal of Tropical Medicine and Hygiene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Global Health Research; St. Michael's Hospital","funders":"","keywords":"Selection (genetic algorithm); Process (computing); Site selection; Genetically modified organism; Key (lock); Biotechnology; Biology; Management science; Engineering ethics; Risk analysis (engineering); Computer science; Political science; Engineering; Business; Ecology; Artificial intelligence; Genetics","score_opus":0.07261328659322612,"score_gpt":0.4069242724658889,"score_spread":0.3343109858726628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149672766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94084305,0.00053240545,0.051833637,0.006609172,0.000026016522,0.00013134227,0.0000035171715,0.000002358653,0.000018479384],"genre_scores_gemma":[0.9805781,0.00065553875,0.017691402,0.0003978508,0.00062667753,0.0000133610965,0.0000032404425,0.000009366371,0.000024429446],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99931586,0.000043534663,0.0001973789,0.00013678503,0.00013600908,0.00017043346],"domain_scores_gemma":[0.9991276,0.00018076017,0.000063684914,0.00004498874,0.00046906542,0.00011389795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016947,0.00007930416,0.00021019793,0.00005507778,0.0002246819,0.00001119097,0.00003475805,0.0000645376,0.0000019170568],"category_scores_gemma":[0.0004796529,0.000052732736,0.000033117543,0.000070549664,0.00068807596,0.0000032875653,0.000015164129,0.0001759742,3.69289e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001639655,0.000093582465,0.0075142807,0.00008973524,0.0002651137,0.000009194605,0.001991645,0.00042286326,0.9537649,0.0020234806,0.014195742,0.017989809],"study_design_scores_gemma":[0.038269516,0.2020098,0.3509803,0.000582374,0.0013406391,0.010030343,0.014672668,0.014267476,0.22170466,0.0072978055,0.13655296,0.0022914587],"about_ca_topic_score_codex":0.000017090106,"about_ca_topic_score_gemma":0.000025456817,"teacher_disagreement_score":0.73206025,"about_ca_system_score_codex":0.0000063533066,"about_ca_system_score_gemma":0.000061328865,"threshold_uncertainty_score":0.25352445},"labels":[],"label_agreement":null},{"id":"W2150856504","doi":"10.1101/gad.227132.113","title":"Repurposing CRISPR/Cas9 for in situ functional assays","year":2013,"lang":"en","type":"article","venue":"Genes & Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cegep de Saint Hyacinthe; Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Cas9; Genome editing; Computational biology; Trans-activating crRNA; Genetics; Gene; Genome","score_opus":0.012412392819287256,"score_gpt":0.2702902064678475,"score_spread":0.2578778136485603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150856504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85235757,0.0028665583,0.14292493,0.00012469564,0.00039098627,0.0004484274,0.0000019247625,0.000017857532,0.0008670293],"genre_scores_gemma":[0.96405923,0.00012915881,0.034017548,0.0001925503,0.00019792374,0.00032597792,0.00012770286,0.000023392466,0.00092651765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991799,0.00000904602,0.00020579189,0.00026757343,0.00008830948,0.00024938738],"domain_scores_gemma":[0.99969596,0.000008765488,0.000026747857,0.00014690778,0.00006612455,0.00005552052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012940225,0.00012328173,0.00009361015,0.000048411694,0.00005806388,0.00002424198,0.00007954925,0.0000833074,0.00003491952],"category_scores_gemma":[0.00002264155,0.0001254702,0.000041159245,0.00005264856,0.000011101232,0.0000031334557,0.000065161745,0.000036667643,0.000025246605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000144134465,0.00002772697,0.0024996975,0.000023472101,0.000027861313,8.134714e-7,0.000082761064,0.00078352966,0.91966796,0.000023936003,0.0037207797,0.07312704],"study_design_scores_gemma":[0.00035013203,0.000032580363,0.03372166,0.000010704153,0.0000038524627,0.00000830805,0.000067723304,0.00008837778,0.7726079,0.00005528154,0.19285968,0.00019380469],"about_ca_topic_score_codex":0.000008450116,"about_ca_topic_score_gemma":0.000056966914,"teacher_disagreement_score":0.18913889,"about_ca_system_score_codex":0.00002809839,"about_ca_system_score_gemma":0.00008465225,"threshold_uncertainty_score":0.5116526},"labels":[],"label_agreement":null},{"id":"W2151144872","doi":"10.1177/03063127030333002","title":"The Drugs Don't Work","year":2003,"lang":"en","type":"article","venue":"Social Studies of Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":331,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Vision; Pharmacogenetics; Emerging technologies; Engineering ethics; Sociology; Set (abstract data type); Computer science; Biology; Engineering; Genetics","score_opus":0.012714389972256341,"score_gpt":0.3378526086344825,"score_spread":0.3251382186622262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151144872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98409104,0.008110202,0.00027348194,0.00027290077,0.00040041885,0.000058965597,7.122778e-7,0.0000042236725,0.006788071],"genre_scores_gemma":[0.99893284,0.0004900016,0.00019500648,0.000027956152,0.00005995153,0.000004062464,1.085649e-7,0.0000023729294,0.00028767734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995329,0.000009135255,0.00007067998,0.00010779529,0.00012606419,0.00015346146],"domain_scores_gemma":[0.9997727,0.000013552434,0.0000236225,0.000085111715,0.00008797023,0.000016993483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038940963,0.000042837833,0.000051222756,0.000007804379,0.00059156056,0.000009152454,0.00015877333,0.000016689102,9.1400995e-7],"category_scores_gemma":[0.00024072647,0.00003004588,0.000030415806,0.00020034196,0.0013701147,0.0000011236,0.00007241921,0.00002354942,8.5824746e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004273501,0.000060281625,0.0061491956,0.000039177557,0.00019172524,7.8286246e-7,0.014094786,0.00024694376,0.8939106,0.01940581,0.017814387,0.048043575],"study_design_scores_gemma":[0.0003165836,0.00011346927,0.011279821,0.0000125431425,0.000016324102,0.0000011485375,0.031702895,0.0000023898765,0.76739997,0.0012444413,0.18765834,0.00025206615],"about_ca_topic_score_codex":0.0000018974317,"about_ca_topic_score_gemma":0.0000039849647,"teacher_disagreement_score":0.16984396,"about_ca_system_score_codex":0.0000073734523,"about_ca_system_score_gemma":0.00003507705,"threshold_uncertainty_score":0.50482446},"labels":[],"label_agreement":null},{"id":"W2152836285","doi":"10.1128/aem.01444-12","title":"Recovery of Phenotypes Obtained by Adaptive Evolution through Inverse Metabolic Engineering","year":2012,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondation Chalmers; Novo Nordisk Fonden; Knut och Alice Wallenbergs Stiftelse","keywords":"Phenotype; Adaptive evolution; Metabolic engineering; Biology; Computational biology; Synthetic biology; Evolutionary biology; Biological system; Genetics; Gene","score_opus":0.0030707623335001254,"score_gpt":0.18670770941227163,"score_spread":0.1836369470787715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152836285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9774377,0.0068159793,0.015242183,0.0000059532276,0.00009003287,0.00010056499,0.00008021704,0.000006674821,0.00022070987],"genre_scores_gemma":[0.9970045,0.000595134,0.0019501258,0.000054429904,0.00007730528,0.000011362937,0.00024642184,0.00001428413,0.00004641433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994931,0.000009367964,0.00011619058,0.00015920174,0.000017570157,0.00020454348],"domain_scores_gemma":[0.999814,0.0000069209436,0.000034954905,0.0001039632,0.0000014656132,0.000038724855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047445385,0.00012242892,0.00013102134,0.000015905118,0.000023049723,0.000001499663,0.000047614016,0.00011422562,0.000015034912],"category_scores_gemma":[0.000002795492,0.00012245504,0.00003291796,0.00002127144,0.000073817915,0.0000040919595,0.000076019816,0.00004733904,0.000005805045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028250803,0.00003607391,0.00094089034,0.000006553242,0.000053099207,4.5826138e-8,0.00006831135,0.00027545152,0.9975602,0.00023276536,0.00030295725,0.00049538654],"study_design_scores_gemma":[0.00040091158,0.00009727812,0.0037473857,0.0000026377645,0.000032757074,0.000015594846,0.00022720273,0.000030735697,0.9696638,0.000025628859,0.025568932,0.00018711018],"about_ca_topic_score_codex":0.0000090494195,"about_ca_topic_score_gemma":8.9220293e-7,"teacher_disagreement_score":0.02789639,"about_ca_system_score_codex":0.0000111643285,"about_ca_system_score_gemma":0.0000033733318,"threshold_uncertainty_score":0.49935716},"labels":[],"label_agreement":null},{"id":"W2153107331","doi":"10.1186/1746-5354-7-1-20","title":"Structural genomics and the organisation of open science","year":2011,"lang":"en","type":"article","venue":"Genomics Society and Policy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Christian Studies; University of Toronto","funders":"Brookhaven National Laboratory; Argonne National Laboratory; SLAC National Accelerator Laboratory; High Energy Physics; RIKEN; Hokkaido University; University of California, San Diego; University College London; University of Toronto; Case Western Reserve University; Karolinska Institutet; University of Texas Southwestern Medical Center; Ministry of Education, Culture, Sports, Science and Technology; University of Miami; University of Oxford; Northwestern University","keywords":"Open science; Intellectual property; Genomics; Engineering ethics; Field (mathematics); Sociology of scientific knowledge; Scientific field; Structural genomics; Data science; Sociology; Political science; Social science; Biology; Engineering; Computer science; Genome; Work (physics); Genetics","score_opus":0.014565036290954828,"score_gpt":0.2951044645618776,"score_spread":0.28053942827092276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153107331","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978624,0.0005387708,0.000565013,0.00012711219,0.000030714098,0.00011887836,0.000008769641,0.0000016762921,0.0007466506],"genre_scores_gemma":[0.9953999,0.0010650859,0.0031525514,0.00022763482,0.000092451424,0.000002154351,0.0000038079927,0.0000062296967,0.000050185583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963856,0.000007723908,0.00008612284,0.00013028336,0.00003153777,0.000105773855],"domain_scores_gemma":[0.99974877,0.0000051479055,0.000036451893,0.00014903738,0.00002348378,0.000037123897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022509617,0.000058497935,0.00007010131,0.00000958051,0.00012807306,0.000031627693,0.0002460877,0.000039911407,0.0000031619065],"category_scores_gemma":[0.000017850287,0.000044980487,0.000026130798,0.000050784594,0.00045460023,0.0000043427654,0.00040617163,0.000032773845,2.4276198e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005950358,0.000005407067,0.0012815314,0.000021269761,0.000044465156,5.0526328e-8,0.014677012,0.00006143476,0.9641521,0.014713306,0.00009678591,0.00488714],"study_design_scores_gemma":[0.0027143732,0.00017315552,0.05358063,0.000005928083,0.00005504895,0.00005331648,0.003810571,0.002629846,0.9195996,0.009578315,0.0074307416,0.00036846177],"about_ca_topic_score_codex":0.00024776082,"about_ca_topic_score_gemma":0.000010779818,"teacher_disagreement_score":0.052299097,"about_ca_system_score_codex":0.0000104877345,"about_ca_system_score_gemma":0.00012483813,"threshold_uncertainty_score":0.1834251},"labels":[],"label_agreement":null},{"id":"W2154082780","doi":"10.1186/s13071-015-0716-6","title":"Silencing the buzz: a new approach to population suppression of mosquitoes by feeding larvae double-stranded RNAs","year":2015,"lang":"en","type":"article","venue":"Parasites & Vectors","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Doublesex; Sterile insect technique; RNA interference; Population; Aedes aegypti; Mating; Biotechnology; Gene knockdown; Vector (molecular biology); Genetics; Gene; Larva; Ecology; PEST analysis; Botany; RNA","score_opus":0.02223803550170427,"score_gpt":0.31501111255134334,"score_spread":0.29277307704963906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154082780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98605084,0.00063259824,0.012282404,0.00005636446,0.00016222936,0.00019967816,0.0000055548194,0.000015280755,0.0005950739],"genre_scores_gemma":[0.99818534,0.000016050431,0.0011291435,0.000027188973,0.00020740654,0.0000113681535,0.00010485728,0.000018121458,0.00030050948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992146,0.000021914666,0.00017788341,0.00023072504,0.00016206515,0.00019280941],"domain_scores_gemma":[0.99954194,0.00001332135,0.000051333293,0.000218529,0.00004054553,0.00013435898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017363341,0.00013112806,0.00013100135,0.000032624324,0.000040796138,0.000023239958,0.00017070958,0.000085932625,0.000005430247],"category_scores_gemma":[0.00006178742,0.00009915238,0.000056944977,0.0001194008,0.0000143869,0.000005030288,0.000058774076,0.00006237926,0.0000038429766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008357396,0.000024798646,0.014799466,0.000016288386,0.00002418774,1.3323071e-7,0.0006685092,0.014201461,0.9635754,0.000011618603,0.00595881,0.00063572975],"study_design_scores_gemma":[0.0005787419,0.00009339938,0.013357099,0.00002268904,0.000028952922,0.0000051668617,0.00027919144,0.0007377035,0.981337,0.000019807432,0.0033700832,0.00017017833],"about_ca_topic_score_codex":0.00040498082,"about_ca_topic_score_gemma":0.000023805886,"teacher_disagreement_score":0.017761564,"about_ca_system_score_codex":0.000013832717,"about_ca_system_score_gemma":0.000026208965,"threshold_uncertainty_score":0.40433168},"labels":[],"label_agreement":null},{"id":"W2154401446","doi":"10.1093/nar/gkv993","title":"Nuclear domain ‘knock-in’ screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":290,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; Beatrice Hunter Cancer Research Institute","keywords":"CRISPR; Biology; Genome editing; Cas9; Homology directed repair; Gene; Homologous recombination; Genome engineering; Genetics; Enhancer; Genome; Computational biology; Gene knockin; Endonuclease; Locus (genetics); DNA repair; Nucleotide excision repair; Transcription factor","score_opus":0.05882218591989418,"score_gpt":0.39669574670694213,"score_spread":0.33787356078704794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154401446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96306586,0.0010131397,0.034888964,0.00020306345,0.00003836475,0.00054169534,0.000016345763,0.0000029799012,0.00022960172],"genre_scores_gemma":[0.99795264,0.00004453772,0.0017852712,0.0000106716525,0.00008896686,0.000044654334,0.000030007635,0.000017688255,0.000025542373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898523,0.000098878096,0.00022479852,0.00019597122,0.00031114757,0.00018399036],"domain_scores_gemma":[0.99912745,0.000052291984,0.000056748013,0.00026606704,0.00044977874,0.00004764773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026972517,0.00006392971,0.000091714115,0.00008751704,0.0000498089,0.000014693268,0.00018512104,0.00007746701,0.0000070233345],"category_scores_gemma":[0.00048907736,0.00005657677,0.00003524315,0.0001459838,0.00012405313,0.0000031411582,0.00007437827,0.00008162513,9.61651e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000998421,0.000023364866,0.0003734293,0.000050779734,0.000015404137,1.3038543e-7,0.00027020986,0.002483605,0.99286383,0.00005895393,0.00014531887,0.0036150997],"study_design_scores_gemma":[0.0013891095,0.000435151,0.009855544,0.000027624186,0.00001924491,0.0000011063906,0.0018665676,0.05077531,0.93325263,0.0002422982,0.0020297659,0.00010564494],"about_ca_topic_score_codex":0.000051292925,"about_ca_topic_score_gemma":0.000032967426,"teacher_disagreement_score":0.059611227,"about_ca_system_score_codex":0.000027646864,"about_ca_system_score_gemma":0.00009290647,"threshold_uncertainty_score":0.23071337},"labels":[],"label_agreement":null},{"id":"W2154619004","doi":"10.1152/physiol.00009.2004","title":"Deciphering the Renal Code: Advances in Conditional Gene Targeting","year":2004,"lang":"en","type":"review","venue":"Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Gene silencing; Conditional gene knockout; Gene; Biology; Recombinase; RNA interference; Gene targeting; Gene expression; Gene knockout; Computational biology; Transgene; Regulation of gene expression; Function (biology); Cre recombinase; Genetics; Bioinformatics; RNA; Phenotype; Genetically modified mouse","score_opus":0.013108745061119859,"score_gpt":0.34871095916249445,"score_spread":0.3356022141013746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154619004","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001920177,0.9971927,0.0020170808,0.00000858767,0.0002067382,0.00020693507,0.000068470756,0.000008915277,0.00009856643],"genre_scores_gemma":[0.0015910185,0.9959906,0.00049136573,0.000035253055,0.0006032311,0.000119645076,0.0010968494,0.00003539235,0.0000366616],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99884796,0.00007509422,0.0003289389,0.00039141896,0.00006559035,0.00029096825],"domain_scores_gemma":[0.99953663,0.00004163645,0.00011226495,0.0002533332,0.000021445087,0.000034699406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011907988,0.00025749757,0.0004902422,0.00003740955,0.00005667412,0.00000775935,0.00028435746,0.00021865118,0.000025392306],"category_scores_gemma":[0.00005358459,0.00018676056,0.00019941453,0.000096178424,0.000083458275,0.000002235512,0.00013813598,0.00023416804,0.000015023876],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006388539,0.00017509288,0.00001448481,0.01163773,0.0004888089,0.00003682899,0.000098578246,0.06660208,0.15039065,0.00090145785,0.0011702526,0.76842016],"study_design_scores_gemma":[0.00014926663,0.000043583263,0.000030773434,0.0005446522,0.000038460494,0.000030858675,0.0000060726547,0.000011772892,0.0011634659,0.0002731153,0.9974741,0.00023392795],"about_ca_topic_score_codex":0.0000032996377,"about_ca_topic_score_gemma":0.000015767428,"teacher_disagreement_score":0.9963038,"about_ca_system_score_codex":0.000029556204,"about_ca_system_score_gemma":0.00012555101,"threshold_uncertainty_score":0.7615875},"labels":[],"label_agreement":null},{"id":"W2155922578","doi":"10.1503/cmaj.100035","title":"The continuing barriers to research in China","year":2010,"lang":"en","type":"letter","venue":"Canadian Medical Association Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"China; Library science; Data science; Operations research; Engineering ethics; Political science; Computer science; World Wide Web; Engineering; Law","score_opus":0.0054638476995201735,"score_gpt":0.29834431609516104,"score_spread":0.29288046839564086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155922578","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.024695756,0.00058238354,0.00006847103,0.9712423,0.0018721259,0.00015097238,0.000024069304,0.0000026625419,0.0013612575],"genre_scores_gemma":[0.11741732,0.0010874001,0.00013581394,0.8287304,0.04451446,0.000054817858,0.00012738275,0.00010783075,0.007824603],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974692,0.00023041439,0.00029165042,0.00019677015,0.0010212951,0.00079070614],"domain_scores_gemma":[0.998253,0.00009865395,0.00006348932,0.00018605734,0.00023069058,0.0011681091],"candidate_categories":["research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0037241066,0.00012163138,0.00013733534,0.00019468594,0.0002478458,0.00016267129,0.00051463756,0.0020469686,0.00031452754],"category_scores_gemma":[0.0049344073,0.00010090029,0.00007708749,0.00017380544,0.000041725147,0.0000015982403,0.000046332803,0.0077065835,0.000031262105],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000018097357,6.8952744e-7,0.0008887028,0.0000030602837,0.000022248909,0.00021652311,0.00010398436,0.0000074503423,0.00023047396,0.0000023444168,0.98830533,0.010217407],"study_design_scores_gemma":[0.00015245867,0.000029564782,0.0011058556,0.00004781239,0.0000028574225,0.00007855108,0.00008045324,0.00001605168,0.00012306229,0.000028213753,0.99821645,0.00011868087],"about_ca_topic_score_codex":0.0014454399,"about_ca_topic_score_gemma":0.08290909,"teacher_disagreement_score":0.14251193,"about_ca_system_score_codex":0.00029140318,"about_ca_system_score_gemma":0.002189575,"threshold_uncertainty_score":0.99924856},"labels":[],"label_agreement":null},{"id":"W2156970726","doi":"10.1038/nbt1204supp-dc31","title":"Indian biotechnology—rapidly evolving and industry led","year":2004,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Public Health; Ontario Genomics; Public Health Ontario; University of Toronto","funders":"Wockhardt","keywords":"Biotechnology; Business; Biology","score_opus":0.0024755996892975784,"score_gpt":0.2545373152454151,"score_spread":0.25206171555611756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156970726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805762,0.009914108,0.003045969,0.0055147125,0.00031352503,0.0001799177,0.000011271943,0.00020128132,0.00024297024],"genre_scores_gemma":[0.9939885,0.0005730055,0.004701233,0.00041714023,0.0001525042,0.000012898075,0.00002404737,0.000032443888,0.00009819975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879825,0.0000107450705,0.00017352749,0.0005399226,0.000084404535,0.00039315526],"domain_scores_gemma":[0.9993036,0.000006055112,0.00005380979,0.0005236792,0.00003462115,0.00007828337],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00010635292,0.00023362534,0.00019052725,0.00025026873,0.00009224503,0.000018426292,0.00030650827,0.0058506518,0.000011888842],"category_scores_gemma":[0.00022179121,0.0002341587,0.000053067506,0.000284204,0.00023975137,0.0000039818037,0.00027378346,0.0016019115,0.000008445157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014426157,0.000030594663,0.00064278574,0.000019650735,0.000053421354,0.000027674783,0.000025289823,0.000051054634,0.9860985,0.0036423714,0.00039119073,0.009003029],"study_design_scores_gemma":[0.00075552287,0.00025423954,0.0020774368,0.000023215332,0.000013914813,0.0002808711,0.00013317712,0.000008788741,0.9658963,0.0008518046,0.029413078,0.00029164887],"about_ca_topic_score_codex":0.000012016463,"about_ca_topic_score_gemma":0.000068277244,"teacher_disagreement_score":0.029021887,"about_ca_system_score_codex":0.000024466084,"about_ca_system_score_gemma":0.000058757112,"threshold_uncertainty_score":0.99543995},"labels":[],"label_agreement":null},{"id":"W2157028755","doi":"10.1534/genetics.105.045641","title":"The Purine Synthesis Gene <i>Prat2</i> Is Required for Drosophila Metamorphosis, as Revealed by Inverted-Repeat-Mediated RNA Interference","year":2005,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"Canadian Institutes of Health Research; New Brunswick Innovation Foundation","keywords":"RNA interference; Biology; Drosophila melanogaster; Genetics; Gene; Phenotype; Transgene; Metamorphosis; RNA; Larva; Botany","score_opus":0.009437515793960106,"score_gpt":0.26848335571953336,"score_spread":0.25904583992557323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157028755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93822557,0.030146362,0.0235081,0.0053157113,0.0005137638,0.0010123627,0.0005106692,0.00008310726,0.0006843797],"genre_scores_gemma":[0.9823207,0.007585299,0.005737379,0.0014244085,0.000535508,0.00023473866,0.0002034472,0.00007885215,0.0018796232],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982804,0.000050949377,0.00043957747,0.0005249154,0.00019376192,0.00051037595],"domain_scores_gemma":[0.99867314,0.00010008359,0.000119734126,0.0007758142,0.00015444861,0.00017677556],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002773815,0.0003177578,0.0002482826,0.000037113696,0.00020207201,0.00007263931,0.0005291137,0.00021728885,0.000030407246],"category_scores_gemma":[0.00025554895,0.000269371,0.0001756774,0.00012920752,0.00011049155,0.000004487327,0.00018172883,0.000110651985,0.000043039567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006901684,0.000041328472,0.00009621542,0.000017547005,0.0001435482,8.4211825e-7,0.000043597152,0.00012161126,0.9259415,0.00000913238,0.062164918,0.0113507295],"study_design_scores_gemma":[0.00039266524,0.00017766577,0.00008969996,0.000011460824,0.0000756292,0.000014039126,0.000029720337,0.0010650273,0.7532268,0.000038441853,0.24460688,0.00027194634],"about_ca_topic_score_codex":0.000010291072,"about_ca_topic_score_gemma":0.00005069785,"teacher_disagreement_score":0.18244196,"about_ca_system_score_codex":0.00002631687,"about_ca_system_score_gemma":0.000071361115,"threshold_uncertainty_score":0.99997586},"labels":[],"label_agreement":null},{"id":"W2157131730","doi":"10.1093/protein/gzh090","title":"Combinatorial exploration of the catalytic site of a drug-resistant dihydrofolate reductase: creating alternative functional configurations","year":2004,"lang":"en","type":"article","venue":"Protein Engineering Design and Selection","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Armand Frappier Museum","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Active site; Dihydrofolate reductase; Mutagenesis; Point mutation; Context (archaeology); Binding site; Mutation; Enzyme; Biology; Stereochemistry; Chemistry; Biochemistry","score_opus":0.009148863680971689,"score_gpt":0.23088920162940857,"score_spread":0.2217403379484369,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157131730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5076287,0.00015973473,0.4918009,0.00002508021,0.00009590631,0.00026352238,0.0000037544546,0.00000837857,0.000014078849],"genre_scores_gemma":[0.99770135,0.000014395628,0.0020929386,0.0000017834433,0.00008931498,0.000045459397,0.000016259411,0.000011277569,0.00002719978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99950594,0.00002051733,0.00016554595,0.00012837326,0.000094737574,0.00008486265],"domain_scores_gemma":[0.9997472,0.000009712076,0.00006850857,0.000072998446,0.00007851017,0.000023035924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120469565,0.0000874755,0.00008343417,0.0000406633,0.000058144662,0.000008961716,0.000034810157,0.000043685704,0.0000011843738],"category_scores_gemma":[0.00007752618,0.00007826194,0.00003439065,0.00012237292,0.000023140781,0.000011048032,0.000015755702,0.000061085295,1.8833573e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003829007,0.000015680684,0.000009208326,0.00002848349,0.000021250846,6.975478e-8,0.00015034177,0.26867214,0.729955,0.0010620744,0.0000027786293,0.000044669912],"study_design_scores_gemma":[0.0004770804,0.00012888957,0.0003813235,0.000054441785,0.000018054488,0.0000041517264,0.000021008631,0.014982219,0.9834345,0.00037384074,0.00004450544,0.00007999593],"about_ca_topic_score_codex":0.000051587587,"about_ca_topic_score_gemma":0.000004635303,"teacher_disagreement_score":0.49007273,"about_ca_system_score_codex":0.000018260656,"about_ca_system_score_gemma":0.000043121978,"threshold_uncertainty_score":0.3191429},"labels":[],"label_agreement":null},{"id":"W2157838834","doi":"10.1038/nsmb.2042","title":"Recognition and maturation of effector RNAs in a CRISPR interference pathway","year":2011,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Trans-activating crRNA; Biology; CRISPR interference; Effector; Thermus thermophilus; Genetics; RNA; Endonuclease; Gene; RNA silencing; RNA interference; Gene silencing; Argonaute; Cas9; Computational biology; Cell biology","score_opus":0.008358641331487102,"score_gpt":0.30793171602078556,"score_spread":0.29957307468929845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157838834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98960245,0.0025299473,0.0072648935,0.000021728549,0.00020637685,0.00016063968,0.00003185902,0.000007543923,0.00017458272],"genre_scores_gemma":[0.99729216,0.000054568707,0.002293756,0.00010372503,0.000041334602,0.000009573275,0.00018820421,0.0000114712375,0.0000052309447],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999281,0.00006576402,0.00017782618,0.00027646194,0.00003818994,0.00016076579],"domain_scores_gemma":[0.9996828,0.0000065545687,0.000059000642,0.0001564679,0.000057787067,0.000037422036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000070611364,0.00014238963,0.00015178914,0.00007394947,0.000013954334,0.000004329777,0.0001001244,0.0003883396,0.000016025653],"category_scores_gemma":[0.000090923124,0.0001237093,0.000045508787,0.00007695075,0.00006646372,0.0000033182976,0.00006774714,0.00021179215,0.0000011077002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012467922,0.0000052554337,0.0011287606,0.000026115249,0.00001859162,0.000003926306,0.00008110862,0.0000026360417,0.9873879,0.0002622337,0.000008352902,0.010950469],"study_design_scores_gemma":[0.0003588594,0.0003342913,0.026016189,0.00002065705,0.000008712987,0.00003657298,0.00002292232,0.000044978107,0.9711283,0.0017432342,0.00013664235,0.00014862786],"about_ca_topic_score_codex":0.000038149206,"about_ca_topic_score_gemma":0.000040379666,"teacher_disagreement_score":0.024887428,"about_ca_system_score_codex":0.0000061057985,"about_ca_system_score_gemma":0.00001489779,"threshold_uncertainty_score":0.50447184},"labels":[],"label_agreement":null},{"id":"W2158177206","doi":"10.1080/13556210410001674040","title":"Genetic study of alcoholism and novel gene expression in the alcoholic brain","year":2004,"lang":"en","type":"review","venue":"Addiction Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Neuroscience; Psychology; Gene expression; Gene; Genetics; Biology","score_opus":0.026327227069890328,"score_gpt":0.37355247673231956,"score_spread":0.34722524966242924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158177206","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013454033,0.98384917,0.0016739961,0.000011425707,0.00017694636,0.00073095417,0.000047328165,0.0000070300307,0.000049093553],"genre_scores_gemma":[0.047062196,0.95192176,0.0003483276,0.0000439939,0.00021404332,0.00016484514,0.00019489878,0.000029628845,0.000020292513],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986842,0.00016530592,0.00044518572,0.0004372878,0.00006812495,0.00019987028],"domain_scores_gemma":[0.99931145,0.000046590958,0.00015911875,0.0004255552,0.000022298571,0.000035019042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021456346,0.00026123514,0.0005229025,0.00013902018,0.000039867522,0.000007606835,0.00024437023,0.00038355883,0.0000068670156],"category_scores_gemma":[0.00004993233,0.00018274307,0.000108198365,0.00015482359,0.00006578818,0.000001285171,0.00012903407,0.00018421667,0.0000015944788],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051639843,0.00148155,0.00071851414,0.0026014375,0.00067397655,0.000025130703,0.0013713816,0.0006460892,0.10744353,0.00014263761,0.0008327747,0.8840113],"study_design_scores_gemma":[0.0017873537,0.0012931912,0.002221664,0.0009912372,0.00033239552,0.00039007014,0.0002131353,0.0000049783644,0.001503858,0.000034877812,0.9907191,0.00050817576],"about_ca_topic_score_codex":0.000047383302,"about_ca_topic_score_gemma":0.0000405806,"teacher_disagreement_score":0.9898863,"about_ca_system_score_codex":0.000012918313,"about_ca_system_score_gemma":0.00005708591,"threshold_uncertainty_score":0.7452046},"labels":[],"label_agreement":null},{"id":"W2158332203","doi":"10.1101/015412","title":"Systematic discovery and classification of human cell line essential genes","year":2015,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canada Research Chairs","keywords":"CRISPR; Biology; Gene; Computational biology; Genetics; RNA interference; Human genome; Context (archaeology); Genome; Genome editing; Function (biology); RNA","score_opus":0.011737301720871665,"score_gpt":0.25784785808401306,"score_spread":0.2461105563631414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158332203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9791294,0.009272982,0.010597768,0.0000139444355,0.00036535418,0.00048380237,0.000095829346,0.000032136286,0.000008801716],"genre_scores_gemma":[0.9981192,0.00047827963,0.00085241,0.00000929187,0.00037601206,0.00007743051,0.0000029913333,0.00006573007,0.000018668354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984821,0.00007137213,0.0004878235,0.000554012,0.00018963704,0.00021502712],"domain_scores_gemma":[0.9983971,0.000010046616,0.00032887785,0.00085571746,0.0002845376,0.00012372877],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036491032,0.00031408205,0.0004369928,0.00009894076,0.000046586763,0.000079708385,0.00026021476,0.00037951153,0.0000017281305],"category_scores_gemma":[0.00007172857,0.00032477744,0.000097735574,0.00008837416,0.000080605205,0.000006606138,0.0003593124,0.00017124275,0.0000025624015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009377212,0.000057272835,0.0006971098,0.007929424,0.00008473063,0.0000020320635,0.0000050578487,0.00021109167,0.9908747,0.000055624907,0.000073348856,1.9311908e-7],"study_design_scores_gemma":[0.00030091288,0.00008717494,0.006064099,0.00077473,0.00016759089,2.0279778e-8,0.000006839052,0.00043272314,0.991714,0.0000010653415,0.0000853729,0.0003654996],"about_ca_topic_score_codex":0.000012175872,"about_ca_topic_score_gemma":0.0000025750735,"teacher_disagreement_score":0.018989805,"about_ca_system_score_codex":0.000028098846,"about_ca_system_score_gemma":0.0001719623,"threshold_uncertainty_score":0.9999204},"labels":[],"label_agreement":null},{"id":"W2159358696","doi":"10.1007/s00335-012-9422-2","title":"The mammalian gene function resource: the international knockout mouse consortium","year":2012,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":328,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia; University of Calgary; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; SickKids Foundation; Ottawa Hospital; University of Manitoba; Genome Canada","funders":"National Center for Research Resources; National Human Genome Research Institute; National Cancer Institute; National Institutes of Health; European Commission; Genome Canada","keywords":"Biology; Gene; Gene knockout; Genome; Genetics; Conditional gene knockout; Mutant; Computational biology; Gene targeting; Knockout mouse; Embryonic stem cell; Phenotype","score_opus":0.008226420181141735,"score_gpt":0.2492534941420355,"score_spread":0.24102707396089376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159358696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97832704,0.0047887154,0.006815411,0.0018610464,0.0013564606,0.00030392606,0.000044226188,0.000038498194,0.006464678],"genre_scores_gemma":[0.97615176,0.000093816016,0.0001342798,0.0005094279,0.0016575475,0.000039213148,0.00011913723,0.000031836174,0.021262966],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989909,0.00004402543,0.00019831091,0.00020265506,0.00017467585,0.0003894584],"domain_scores_gemma":[0.9992806,0.00001573935,0.000058637754,0.000494063,0.000044606026,0.000106371735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040428393,0.00015285113,0.00007433879,0.000024505298,0.0002572386,0.00007682089,0.00041211973,0.00009255917,0.00008794149],"category_scores_gemma":[0.000041581505,0.00010190711,0.00009477657,0.000060560073,0.00008344776,0.0000044262647,0.00017282208,0.00011842748,0.00009275324],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013914802,0.00004416227,0.0046796836,0.000008841282,0.00015524105,0.0000018010109,0.00025978434,0.00068411086,0.97506964,0.0004069806,0.013491314,0.005059299],"study_design_scores_gemma":[0.00019688526,0.00004947658,0.01848163,0.0000010285926,0.000020924288,0.00002758397,0.0002534084,0.000025435043,0.11596704,0.000012105453,0.86481726,0.00014720352],"about_ca_topic_score_codex":0.000012487959,"about_ca_topic_score_gemma":0.000023891122,"teacher_disagreement_score":0.8591026,"about_ca_system_score_codex":0.000022946926,"about_ca_system_score_gemma":0.00002016895,"threshold_uncertainty_score":0.41556516},"labels":[],"label_agreement":null},{"id":"W2159539552","doi":"10.1128/jcm.03104-12","title":"Escherichia coli XL10-Gold Bacteria Produce Bacteriophage","year":2012,"lang":"en","type":"letter","venue":"Journal of Clinical Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Escherichia coli; Bacteriophage; Bacteria; Microbiology; Biology; Enterobacteriaceae; Virology; Genetics; Gene","score_opus":0.0227407255007375,"score_gpt":0.34652027462669005,"score_spread":0.3237795491259525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159539552","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8773247,0.0071442416,0.001012854,0.0963319,0.01709924,0.00044030356,0.00020035658,0.000019961302,0.00042645793],"genre_scores_gemma":[0.18323556,0.0060830903,0.016427984,0.61110306,0.16637081,0.000025292757,0.001993285,0.00048902415,0.014271925],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99640304,0.00043896498,0.0019671987,0.00047957103,0.00008311211,0.00062811474],"domain_scores_gemma":[0.9974399,0.00014784427,0.0013118477,0.00061478873,0.0003033285,0.00018226138],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0012536326,0.0004554886,0.0012222306,0.000100894795,0.00003117471,0.000031068113,0.0007108101,0.0023727587,0.00020690876],"category_scores_gemma":[0.0006268936,0.00037965731,0.0008091072,0.00007528306,0.00021583248,0.0000062642234,0.00024008215,0.0022979497,0.000061307976],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010099577,0.000056387027,0.00027798963,0.00005563099,0.0002519393,0.000042028176,0.0000065349996,0.0000020290558,0.5147076,3.644413e-7,0.48377705,0.000721431],"study_design_scores_gemma":[0.0007807834,0.00084701227,0.0023727014,0.000061391904,0.00017365423,0.00060336286,0.0000036460735,4.5422541e-7,0.038103815,0.0000040266514,0.9566633,0.0003858164],"about_ca_topic_score_codex":0.0000020803488,"about_ca_topic_score_gemma":0.000002189591,"teacher_disagreement_score":0.6940891,"about_ca_system_score_codex":0.0000199271,"about_ca_system_score_gemma":0.00027433204,"threshold_uncertainty_score":0.99986553},"labels":[],"label_agreement":null},{"id":"W2159669306","doi":"10.1093/nar/gkl890","title":"DAXX interacts with phage ΦC31 integrase and inhibits recombination","year":2006,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Key Research and Development Program of China","keywords":"Death-associated protein 6; Integrase; Biology; Tetramer; HEK 293 cells; Molecular biology; Genetics; Gene; Biochemistry; Enzyme; Nuclear protein","score_opus":0.014383563802366571,"score_gpt":0.3415634819682622,"score_spread":0.32717991816589564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159669306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896757,0.0005015715,0.0019893735,0.00019320498,0.000038862385,0.00015495879,0.0000041587828,0.000014565643,0.007427616],"genre_scores_gemma":[0.99692327,0.000089741836,0.00084570213,0.000024857558,0.00012919764,0.000017159573,0.000059698472,0.00002442621,0.0018859514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990634,0.000052849213,0.0001126909,0.00028450903,0.00021065895,0.0002759478],"domain_scores_gemma":[0.99953353,0.00002093635,0.000016437383,0.00021545679,0.00014090782,0.00007274798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033889213,0.00010185271,0.00008060589,0.00010259264,0.000088420624,0.000058201542,0.00011316261,0.00008906417,0.000030335306],"category_scores_gemma":[0.00007625809,0.00008676919,0.000019684869,0.00015444565,0.000100347796,0.0000063887587,0.00012277518,0.00020317876,0.000014606826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011071651,0.0000942483,0.0027426588,0.000040642182,0.000023779576,0.000014267948,0.00009292898,0.000063708976,0.9702367,0.00037541255,0.0056955903,0.020509338],"study_design_scores_gemma":[0.0009766754,0.00070198555,0.012975716,0.00005390989,0.0000069970797,0.00004883608,0.00022167836,0.0005781164,0.95081013,0.00020832937,0.03320757,0.00021006177],"about_ca_topic_score_codex":0.000069634116,"about_ca_topic_score_gemma":0.000089689376,"teacher_disagreement_score":0.027511979,"about_ca_system_score_codex":0.00001422024,"about_ca_system_score_gemma":0.000031692423,"threshold_uncertainty_score":0.35383448},"labels":[],"label_agreement":null},{"id":"W2160189541","doi":"10.1681/asn.2008090986","title":"Dicer Cuts the Kidney","year":2008,"lang":"en","type":"review","venue":"Journal of the American Society of Nephrology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Canada Research Chairs; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Dicer; Kidney; Medicine; Internal medicine; Biology; Genetics; Gene","score_opus":0.01588331187442524,"score_gpt":0.33275296369564666,"score_spread":0.3168696518212214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160189541","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007296975,0.99723226,0.00058826903,0.0009653567,0.0002523943,0.00013641124,0.000016497313,0.000001962323,0.000077136174],"genre_scores_gemma":[0.00020511274,0.9944986,0.00072767574,0.003380168,0.000921805,0.0000039151655,0.000004499721,0.0000322705,0.00022592864],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987174,0.00017883103,0.00055245374,0.00014849438,0.00018550489,0.00021731656],"domain_scores_gemma":[0.99788594,0.00006453207,0.0013843306,0.0004817333,0.00010303843,0.00008043962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020552319,0.00023232937,0.0009493006,0.000023103583,0.00007763125,0.0000052016717,0.00086538197,0.00016591014,0.0000073196793],"category_scores_gemma":[0.00006467312,0.00012035923,0.0019110123,0.00019586956,0.0007324098,0.0000014472974,0.00023209582,0.00046071384,0.0000016201584],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026847343,0.00005548331,0.000017530632,0.0005713154,0.0016594816,0.0000030152546,0.00013631128,0.00006506588,0.006081168,0.0000032008973,0.69671994,0.29466063],"study_design_scores_gemma":[0.00013100398,0.00024567707,0.00008985438,0.00022598312,0.00032765884,0.001042721,0.000045978966,0.0000035781045,0.00011203755,0.000006048509,0.9976555,0.00011393139],"about_ca_topic_score_codex":0.000013956946,"about_ca_topic_score_gemma":0.0000012634163,"teacher_disagreement_score":0.3009356,"about_ca_system_score_codex":0.000021314392,"about_ca_system_score_gemma":0.00040437453,"threshold_uncertainty_score":0.4908107},"labels":[],"label_agreement":null},{"id":"W2162585640","doi":"10.2217/hiv.09.54","title":"At the Forefront of Retrovirology Research: Frontiers of Retrovirology","year":2009,"lang":"en","type":"article","venue":"HIV Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Palette (painting); Mosaic; Virology; Political science; Computer science; Medicine; Geography","score_opus":0.023918437658571698,"score_gpt":0.34301248678411284,"score_spread":0.3190940491255411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162585640","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840197,0.01013856,0.0035289004,0.0008744515,0.00012619754,0.00016417317,0.000013252657,0.000005087544,0.0011296667],"genre_scores_gemma":[0.99600905,0.0021182757,0.00041047626,0.00021850891,0.000107550906,0.0000067205324,0.000026188645,0.000012119111,0.001091126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990816,0.000112601636,0.00020205721,0.00020703339,0.00013908386,0.00025764134],"domain_scores_gemma":[0.9993143,0.00002171938,0.0000636102,0.00049162965,0.00007195431,0.00003677665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004136696,0.00009832225,0.00017396187,0.000056471727,0.00005310696,0.0000023449402,0.00026488095,0.00014886432,0.000032461932],"category_scores_gemma":[0.000043483185,0.00007121541,0.00009384072,0.00008674233,0.00024349654,0.0000012099539,0.000054095788,0.00011712598,0.0000028014188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042397305,0.000037738584,0.0029529308,0.000003176869,0.00004249449,8.0523665e-7,0.0001329927,0.00024602844,0.96542424,0.00013717769,0.025329018,0.005269407],"study_design_scores_gemma":[0.0007676038,0.0018907367,0.021331657,0.0000028115905,0.0000062618915,0.000008309373,0.00008731329,0.00008793441,0.8749444,0.000498818,0.10027903,0.00009515535],"about_ca_topic_score_codex":0.000010097012,"about_ca_topic_score_gemma":0.000014844909,"teacher_disagreement_score":0.090479895,"about_ca_system_score_codex":0.000011470606,"about_ca_system_score_gemma":0.000026627842,"threshold_uncertainty_score":0.290408},"labels":[],"label_agreement":null},{"id":"W2163241233","doi":"10.1038/nrmicro2577","title":"Evolution and classification of the CRISPR–Cas systems","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2496,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université Laval","funders":"National Human Genome Research Institute; National Institutes of Health","keywords":"CRISPR; Biology; CRISPR interference; Computational biology; Palindrome; Trans-activating crRNA; Gene; Genetics; Evolutionary biology; Cas9","score_opus":0.023112144014492745,"score_gpt":0.340033797228329,"score_spread":0.31692165321383625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163241233","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000018955527,0.9969491,0.00094189314,0.000004886965,0.0008270611,0.0009949995,0.00006547045,0.0000051339953,0.00019251538],"genre_scores_gemma":[0.0007267903,0.99837065,0.000101665166,0.000016319691,0.00022427054,0.00007244977,0.00020289578,0.0000285932,0.00025635224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99846095,0.00033234092,0.00058733847,0.00041393787,0.00002413101,0.00018130241],"domain_scores_gemma":[0.99876493,0.000017531596,0.00047955103,0.0006416326,0.000063268286,0.000033105272],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00034703102,0.0003089358,0.0009852592,0.000057212394,0.000039454884,0.0000059674394,0.00033873747,0.0012973584,0.0000038971652],"category_scores_gemma":[0.000101934915,0.00018546039,0.00036500383,0.00013601616,0.00011070537,0.0000012096045,0.00015857362,0.00048262696,0.00001043037],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012428636,0.00006980926,0.000079064346,0.05088477,0.00037121997,6.6808025e-7,0.000036285568,0.000001716789,0.10887325,0.0029684568,0.019425903,0.8172764],"study_design_scores_gemma":[0.000053273656,0.00003718442,0.000040949246,0.0024338816,0.00030640952,0.00020538365,0.0000024359733,6.3076465e-7,0.00031458467,0.0000036092995,0.99642193,0.00017971642],"about_ca_topic_score_codex":0.0000046566306,"about_ca_topic_score_gemma":0.000008970802,"teacher_disagreement_score":0.97699606,"about_ca_system_score_codex":0.000028309638,"about_ca_system_score_gemma":0.00008105571,"threshold_uncertainty_score":0.99999917},"labels":[],"label_agreement":null},{"id":"W2163971374","doi":"10.1016/j.stem.2011.10.012","title":"Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells","year":2011,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":240,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ottawa Hospital","funders":"Canadian Institutes of Health Research; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Biology; Genetics; Somatic cell; Germline; Embryonic stem cell; Ploidy; Stem cell; Mutagenesis; Genome; Cell biology; Mutation; Gene","score_opus":0.014490074864660344,"score_gpt":0.22993725065123344,"score_spread":0.2154471757865731,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163971374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9777575,0.0036754,0.015003971,0.000005318258,0.0001458272,0.00020641976,0.000014848625,0.000014033796,0.0031766484],"genre_scores_gemma":[0.99004894,0.001749181,0.003895496,0.00004436686,0.000050570336,0.000008056944,0.0000130630015,0.000036852685,0.004153449],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991396,0.00002441909,0.00022895928,0.0002959377,0.00009365308,0.00021744755],"domain_scores_gemma":[0.99939626,0.0000074485533,0.00010102754,0.00036668865,0.00005677632,0.00007179433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008096863,0.00017201052,0.0001634912,0.000026409061,0.000037050693,0.000009022233,0.00014327056,0.00015274547,0.000016702292],"category_scores_gemma":[8.338909e-7,0.00017785178,0.00007034008,0.00005701591,0.0000485114,0.0000043840564,0.00010786352,0.000064292326,0.000010249896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022763765,0.000050903374,0.0005908165,0.00019887468,0.000014718305,0.0000013791182,0.00044946658,0.00021670722,0.9970306,0.00001051288,0.0006932129,0.00072003447],"study_design_scores_gemma":[0.00043013875,0.00022386528,0.0001747426,0.000009075841,0.00003371774,0.0000026005744,0.00039903482,0.000116719115,0.9872363,0.000011992829,0.011166816,0.00019497256],"about_ca_topic_score_codex":0.000016420478,"about_ca_topic_score_gemma":0.0000065198733,"teacher_disagreement_score":0.012291431,"about_ca_system_score_codex":0.000008194243,"about_ca_system_score_gemma":0.00003153394,"threshold_uncertainty_score":0.7252585},"labels":[],"label_agreement":null},{"id":"W2164154861","doi":"10.1002/9780470015902.a0023273","title":"<scp>CRISPR</scp> / <scp>Cas</scp> System and Resistance to Bacteriophage Infection","year":2011,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Extrachromosomal DNA; Biology; Trans-activating crRNA; CRISPR interference; Plasmid; Genetics; DNA; Bacteriophage; Cas9; Horizontal gene transfer; RNA; Gene; Computational biology; Genome; Escherichia coli","score_opus":0.007943730804677692,"score_gpt":0.2576960905615082,"score_spread":0.24975235975683052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164154861","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13028336,0.013033431,0.002858097,0.00001054231,0.0014099407,0.00043313077,0.000075505704,0.00008043856,0.8518156],"genre_scores_gemma":[0.14828286,0.01718006,0.010973287,0.00016836128,0.0026950876,0.00012979005,0.0000620615,0.00038321302,0.8201253],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998292,0.00005244373,0.00033134417,0.0006630087,0.00027444467,0.00038674296],"domain_scores_gemma":[0.9990494,0.000057053785,0.0002276058,0.00037610592,0.00005075625,0.0002390403],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003545887,0.00032295892,0.00036357637,0.00024238374,0.00009187878,0.00003331767,0.00034781705,0.00030739265,0.000019445133],"category_scores_gemma":[0.00056436704,0.00030093995,0.0000839173,0.00028757952,0.00021470971,0.000007631248,0.0001792233,0.00011002496,0.000029561064],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004813222,0.000066764405,0.016741484,0.0013535687,0.00012921581,0.000009827915,0.0009792921,0.000047514342,0.023312332,0.00031668317,0.9563383,0.0007002338],"study_design_scores_gemma":[0.00016267764,0.00020995489,0.009133181,0.00024839965,0.000034035616,0.000007255796,0.00034479884,0.0000045226093,0.009314375,0.000010668551,0.98043627,0.00009385812],"about_ca_topic_score_codex":0.00018036223,"about_ca_topic_score_gemma":0.00046527662,"teacher_disagreement_score":0.031690273,"about_ca_system_score_codex":0.000011933318,"about_ca_system_score_gemma":0.00013303402,"threshold_uncertainty_score":0.99994427},"labels":[],"label_agreement":null},{"id":"W2164611473","doi":"10.1186/s13041-014-0051-4","title":"Gene delivery in mouse auditory brainstem and hindbrain using in utero electroporation","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Institut National de la Santé et de la Recherche Médicale","keywords":"Hindbrain; In utero; Brainstem; Electroporation; Neuroscience; Psychopharmacology; Psychology; Audiology; Medicine; Biology; Fetus; Pregnancy; Central nervous system; Gene; Genetics; Psychiatry","score_opus":0.0041881674903732355,"score_gpt":0.2492026588261539,"score_spread":0.24501449133578065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164611473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94440067,0.0005205725,0.054669563,0.00013310759,0.000051853836,0.0001414508,0.000002680319,0.000009994616,0.0000700829],"genre_scores_gemma":[0.9967425,0.000027990303,0.0024293049,0.00052704796,0.00010882277,0.000009793806,0.00005509352,0.00003026997,0.00006920119],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989926,0.00011680614,0.00020316539,0.00033737413,0.000094128336,0.0002559197],"domain_scores_gemma":[0.99964225,0.0000120897985,0.00003710482,0.00023226497,0.000018683926,0.000057604466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032455474,0.0001519064,0.00013797519,0.00012569061,0.000024591947,0.000023123419,0.00009121423,0.0001412402,0.0000020408065],"category_scores_gemma":[0.00009599789,0.0001792242,0.000036250578,0.00010434126,0.000029856807,0.000005355156,0.0000685952,0.00010444422,0.0000011554386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014467903,0.000019479923,0.00086310453,0.000015351434,0.000007557167,0.000020869364,0.000052339805,0.0054341382,0.9911357,0.000040889634,0.00009451887,0.0023015419],"study_design_scores_gemma":[0.0008171452,0.00009973841,0.002731936,0.000013396415,0.0000034696702,0.000028368262,0.000027730102,0.012120848,0.98270625,0.00006426981,0.0011385976,0.00024827107],"about_ca_topic_score_codex":0.000048472008,"about_ca_topic_score_gemma":0.00022176895,"teacher_disagreement_score":0.05234178,"about_ca_system_score_codex":0.000032421933,"about_ca_system_score_gemma":0.00003223743,"threshold_uncertainty_score":0.73085505},"labels":[],"label_agreement":null},{"id":"W2164695230","doi":"10.1371/journal.pone.0098186","title":"Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":996,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Human Genome Research Institute; Life Sciences Research Foundation; National Heart, Lung, and Blood Institute; Damon Runyon Cancer Research Foundation; National Institutes of Health; American Cancer Society","keywords":"CRISPR; Mutagenesis; Cas9; Guide RNA; Biology; Genetics; Computational biology; Genome editing; Mutant; Insertional mutagenesis; Gene","score_opus":0.00932959124334323,"score_gpt":0.2474848134302629,"score_spread":0.23815522218691967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164695230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97845346,0.00032331233,0.020478642,0.000058100966,0.000017996379,0.00022253861,0.000028692688,0.000016023057,0.00040123585],"genre_scores_gemma":[0.9936475,0.000037004505,0.005849911,0.000046206213,0.000054472483,0.000025028387,0.00007748878,0.000021527683,0.00024081909],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920106,0.000033711192,0.00019851528,0.00022778178,0.0001568885,0.0001820247],"domain_scores_gemma":[0.9995735,0.000010541651,0.000059574784,0.00021367868,0.00006647686,0.00007622141],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016858653,0.00011336243,0.00015645075,0.000031639163,0.000035221707,0.000010102876,0.000068525944,0.00008192705,0.000009790398],"category_scores_gemma":[0.00007501356,0.00011567127,0.000031275926,0.00005671541,0.000029619181,0.0000011110236,0.000066204375,0.000045479,0.0000019020206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009958324,0.000541432,0.0016914048,0.00009562184,0.00005568817,3.3302342e-7,0.00002948185,0.000287749,0.9968543,0.0000047553526,0.00006996617,0.00035931662],"study_design_scores_gemma":[0.00046527438,0.00029589282,0.004810458,0.000052835607,0.000043580294,0.000001110645,0.000027600976,0.012755468,0.98013633,0.0000024049953,0.0012722817,0.00013678629],"about_ca_topic_score_codex":0.000019953379,"about_ca_topic_score_gemma":0.000017604265,"teacher_disagreement_score":0.016717987,"about_ca_system_score_codex":0.000011974363,"about_ca_system_score_gemma":0.000015183286,"threshold_uncertainty_score":0.47169375},"labels":[],"label_agreement":null},{"id":"W2164884088","doi":"10.1002/jcb.21912","title":"Retroviral vector silencing during iPS cell induction: An epigenetic beacon that signals distinct pluripotent states","year":2008,"lang":"en","type":"review","venue":"Journal of Cellular Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Hospital for Sick Children","keywords":"Reprogramming; Induced pluripotent stem cell; Biology; Viral vector; Cell biology; Gene silencing; Embryonic stem cell; Genetics; Cell; Gene","score_opus":0.016917572579632497,"score_gpt":0.2870593668631489,"score_spread":0.2701417942835164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164884088","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20787297,0.79010004,0.0012797769,0.0000047798694,0.0004570386,0.0001793227,0.000044066473,0.000012367088,0.0000496482],"genre_scores_gemma":[0.16818552,0.8281088,0.0004190899,0.0000065599625,0.0023110695,0.0000103671855,0.00034480426,0.00012387044,0.00048991916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969936,0.0001329871,0.0011871619,0.00063327816,0.00051571074,0.00053726096],"domain_scores_gemma":[0.9975064,0.000026646183,0.0011584854,0.0007044867,0.00020157229,0.00040242155],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029509293,0.000742712,0.0012592132,0.0001528185,0.00015688203,0.00007512405,0.00066488015,0.0007469128,0.000046366982],"category_scores_gemma":[0.00007020072,0.0006758491,0.0009973367,0.00016930123,0.00011105839,0.000012534612,0.00017505337,0.00079493254,0.0000055948703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000444329,0.00016024409,0.00001939772,0.006646491,0.00031873403,0.0002716955,0.00007315297,0.00029292508,0.96800506,8.123775e-8,0.0003951828,0.023772612],"study_design_scores_gemma":[0.0004237674,0.00036114268,0.000013805462,0.0019037124,0.0004276132,0.0014235085,0.00011438129,0.0000062217355,0.9347696,0.000002269702,0.059821595,0.0007324089],"about_ca_topic_score_codex":0.0000038853273,"about_ca_topic_score_gemma":6.2788524e-7,"teacher_disagreement_score":0.059426412,"about_ca_system_score_codex":0.00015190484,"about_ca_system_score_gemma":0.00047082885,"threshold_uncertainty_score":0.9995693},"labels":[],"label_agreement":null},{"id":"W2164998058","doi":"10.1534/genetics.113.160846","title":"Simultaneous Expression of Multiple Proteins Under a Single Promoter in <i>Caenorhabditis elegans</i> via a Versatile 2A-Based Toolkit","year":2013,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondation Générale de Santé; University of British Columbia; Centre National de la Recherche Scientifique; Fondation ARC pour la Recherche sur le Cancer; Institute of Genetics; Fondation pour la Recherche Médicale","keywords":"Caenorhabditis elegans; Biology; Computational biology; Translation (biology); Genetics; Plasmid; Caenorhabditis; Gene; Cell biology; Messenger RNA","score_opus":0.005919542962265736,"score_gpt":0.23068271719504352,"score_spread":0.22476317423277778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164998058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92146415,0.000417065,0.07725188,0.000063512656,0.00007554447,0.0005981148,0.000018849778,0.000014913499,0.00009597001],"genre_scores_gemma":[0.9844741,0.00001679859,0.01505822,0.00009777534,0.00008406533,0.00007823243,0.00006141481,0.000038431037,0.00009092164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989133,0.00003402786,0.00028570203,0.00031020347,0.0001534452,0.00030335135],"domain_scores_gemma":[0.9993333,0.000030269772,0.00006844821,0.00039552362,0.000091431444,0.00008099556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055200995,0.00018465819,0.0001679306,0.0000610758,0.000026613046,0.000018799748,0.00017454906,0.00017431869,0.000055827924],"category_scores_gemma":[0.00006635587,0.0001864179,0.000068390626,0.000107691194,0.000051860028,0.0000035471191,0.00007966226,0.00008755114,0.000011061604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002286865,0.00014991674,0.0013233398,0.000052514948,0.000008024719,0.0000031741556,0.000069841815,0.04404996,0.95086414,4.0044804e-7,0.00017181298,0.0032840385],"study_design_scores_gemma":[0.00084566313,0.00042218363,0.0013494069,0.000046959438,0.000008130991,0.000004980575,0.000047326714,0.013273988,0.9812006,0.000031181582,0.0025463453,0.00022327513],"about_ca_topic_score_codex":0.00006056057,"about_ca_topic_score_gemma":0.0001720584,"teacher_disagreement_score":0.06300999,"about_ca_system_score_codex":0.000019677213,"about_ca_system_score_gemma":0.000047723457,"threshold_uncertainty_score":0.7601901},"labels":[],"label_agreement":null},{"id":"W2165359856","doi":"10.1093/nar/gkm182","title":"Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases","year":2007,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Seattle Children's Research Institute; Cancer Research Institute","keywords":"Biology; Homing (biology); Cleavage (geology); DNA; Homing endonuclease; Molecular biology; Cell; Endonuclease; Cell biology; Genetics","score_opus":0.01780635800806608,"score_gpt":0.34547723214957504,"score_spread":0.32767087414150897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165359856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99163276,0.0016209251,0.005016916,0.00001404801,0.000034150107,0.00012905804,0.00007606311,0.000011447866,0.0014646323],"genre_scores_gemma":[0.99687916,0.0004962214,0.0020018853,0.000009985852,0.000048409365,0.0000019167974,0.000096948956,0.000031169548,0.00043430997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983348,0.000066206274,0.0002653394,0.00039539405,0.0004128741,0.00052537327],"domain_scores_gemma":[0.99916226,0.00013592027,0.000045116692,0.00035799324,0.00011507987,0.00018365709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012701624,0.00014240912,0.00024291419,0.0006820087,0.00012753588,0.00003846402,0.00023524924,0.00016185765,0.00004716973],"category_scores_gemma":[0.00019245957,0.00014506628,0.000110096415,0.0018520486,0.00013633203,0.0000053944536,0.00023318548,0.00019278249,0.0000068810855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007267223,0.000056220422,0.01690013,0.00004160106,0.00019007603,0.000006120553,0.00009004893,0.000297813,0.9773413,0.0000030394351,0.0013418454,0.0036591412],"study_design_scores_gemma":[0.0004337742,0.00023485889,0.017816415,0.0000086614245,0.00009009312,0.0000027691963,0.00041895715,0.0039390423,0.97358596,0.0000015219383,0.003299866,0.00016810375],"about_ca_topic_score_codex":0.00004678671,"about_ca_topic_score_gemma":0.00002174779,"teacher_disagreement_score":0.0052463934,"about_ca_system_score_codex":0.00002637927,"about_ca_system_score_gemma":0.000025954283,"threshold_uncertainty_score":0.5915631},"labels":[],"label_agreement":null},{"id":"W2165896516","doi":"10.1182/blood-2015-05-646398","title":"MLL leukemia induction by genome editing of human CD34+ hematopoietic cells","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; European Hematology Association","keywords":"Haematopoiesis; Leukemia; Genome editing; Biology; CD34; Genome; Human genome; Cancer research; Genetics; Gene; Computational biology; Immunology; Stem cell","score_opus":0.00969154035577284,"score_gpt":0.2603412472414822,"score_spread":0.25064970688570937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165896516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620646,0.0010724067,0.0012543673,0.000010665108,0.00013974472,0.00006605108,0.000010189792,0.000011598543,0.0012285176],"genre_scores_gemma":[0.9988124,0.000020271813,0.00037175266,0.000016047472,0.0003714207,0.0000055155847,0.000066888904,0.000017081427,0.00031864867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994306,0.0000121535095,0.00015582156,0.00016540806,0.00009352403,0.00014247147],"domain_scores_gemma":[0.99963194,0.0000019746997,0.000051427403,0.00019266746,0.000049029768,0.00007293217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010238338,0.000090873786,0.00009974438,0.00002243894,0.000023896602,0.000007404321,0.00009543119,0.00009641341,0.0000073537285],"category_scores_gemma":[0.000016610682,0.000096794836,0.000041077226,0.000046268735,0.000026019145,0.0000017432873,0.000051890736,0.000056033256,0.000005084161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000001966372,0.000044250897,0.0002181467,0.000023663295,0.000022169499,0.0000011337739,0.000092315786,0.00016634646,0.99803364,0.000006854098,0.0013196105,0.00006991021],"study_design_scores_gemma":[0.00058685517,0.00016022324,0.0002189619,0.0000074985073,0.00002697428,0.000012850944,0.00014971862,0.000007543723,0.9939618,0.000026077058,0.0047362163,0.00010524802],"about_ca_topic_score_codex":0.000020551215,"about_ca_topic_score_gemma":0.0000039400575,"teacher_disagreement_score":0.0040718,"about_ca_system_score_codex":0.000008971796,"about_ca_system_score_gemma":0.000030430938,"threshold_uncertainty_score":0.3947179},"labels":[],"label_agreement":null},{"id":"W2167564168","doi":"10.1002/prot.20802","title":"Binding site‐based classification of coronaviral papain‐like proteases","year":2005,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Papain; Proteases; Virology; Chemistry; Computational biology; Biology; Biochemistry; Enzyme","score_opus":0.008745804075274359,"score_gpt":0.2532463768164164,"score_spread":0.244500572741142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167564168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86046505,0.000250612,0.13828038,0.00008188668,0.000106071326,0.00050356734,0.00007959351,0.000026361058,0.00020648699],"genre_scores_gemma":[0.9735827,0.00001575124,0.025840506,0.00009744805,0.00012105772,0.000017192093,0.000251728,0.000010019875,0.00006360015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937904,0.000011775822,0.00024573551,0.00011543121,0.00011774664,0.0001302897],"domain_scores_gemma":[0.99959725,0.000004286275,0.000115837145,0.00016875516,0.000059897255,0.000053989526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007109097,0.0001269484,0.000099528006,0.00006281231,0.00006675924,0.000020137206,0.000050856037,0.00011875898,0.000027103506],"category_scores_gemma":[0.000028421813,0.00010831883,0.0000407579,0.000078466466,0.000046741996,0.000008311149,0.000026797272,0.00007096279,0.0000033995166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106094674,0.000025115794,0.0028163109,0.00022372248,0.000025861538,7.024302e-8,0.000084089545,0.002073786,0.9492156,0.00007096145,0.00022689874,0.045131516],"study_design_scores_gemma":[0.002230359,0.0010026951,0.038465556,0.000095734664,0.000092728515,0.000026778509,0.00037842346,0.16331282,0.74750584,0.000049442693,0.04619819,0.0006414028],"about_ca_topic_score_codex":0.0000032464368,"about_ca_topic_score_gemma":0.000014735943,"teacher_disagreement_score":0.20170972,"about_ca_system_score_codex":0.000010113492,"about_ca_system_score_gemma":0.000032707772,"threshold_uncertainty_score":0.4417114},"labels":[],"label_agreement":null},{"id":"W2168535398","doi":"10.1038/emboj.2011.377","title":"Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference","year":2011,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Argonne National Laboratory; Natural Sciences and Engineering Research Council of Canada; Government of Canada; National Institutes of Health; Genome Canada; Ontario Genomics; National Institute of General Medical Sciences; Ontario Genomics Institute","keywords":"Biology; Nuclease; Effector; CRISPR; Enzyme; Interference (communication); Genetics; CRISPR interference; RNA interference; Computational biology; Molecular biology; Cell biology; Biochemistry; Gene; RNA; Genome editing","score_opus":0.011394376330062123,"score_gpt":0.2648367254169601,"score_spread":0.25344234908689794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168535398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983555,0.00036283993,0.00080341415,0.000055388977,0.00022559252,0.00007282355,0.000014175526,0.0000013146526,0.00010892405],"genre_scores_gemma":[0.9997103,0.000039217062,0.00006415804,0.00003541398,0.000106275875,5.751388e-7,2.6795578e-7,0.000008279747,0.000035469322],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951947,0.00010495756,0.000109095,0.00008149512,0.00008405086,0.00010095712],"domain_scores_gemma":[0.99948275,0.0000107370115,0.00010233072,0.00032080302,0.00004218662,0.000041189527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015399416,0.000083772524,0.00009003602,0.000009373043,0.000083749714,0.0000092868495,0.0003364965,0.00004563601,0.00003829489],"category_scores_gemma":[0.000050697832,0.000038562463,0.00006863596,0.000037424397,0.00011790753,0.0000034140664,0.00014125399,0.00018632405,1.9889315e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006598362,0.000019257994,0.002341764,0.000015114898,0.000035643858,5.20149e-7,0.00059149275,0.00008638841,0.9948196,0.000016540514,0.0001317194,0.0018759763],"study_design_scores_gemma":[0.0001639163,0.00012613706,0.08731079,0.00002206542,0.000031939526,0.00013218076,0.00008077936,0.000099614736,0.9117072,0.0001517172,0.00012333748,0.000050297665],"about_ca_topic_score_codex":0.000031867952,"about_ca_topic_score_gemma":0.000046335816,"teacher_disagreement_score":0.08496902,"about_ca_system_score_codex":0.0000038104554,"about_ca_system_score_gemma":0.000028705728,"threshold_uncertainty_score":0.15725316},"labels":[],"label_agreement":null},{"id":"W2168933209","doi":"10.1128/jb.01415-07","title":"Diversity, Activity, and Evolution of CRISPR Loci in <i>Streptococcus thermophilus</i>","year":2007,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":795,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Biology; Genetics; Streptococcus thermophilus; Trans-activating crRNA; Locus (genetics); Mobile genetic elements; CRISPR interference; Plasmid; Bacteriophage; Gene; Computational biology; Palindrome; Cas9; Bacteria","score_opus":0.00672331108099971,"score_gpt":0.2689947885452944,"score_spread":0.2622714774642947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168933209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886152,0.0006540197,0.010403875,0.000048511756,0.00011898918,0.000041828374,0.0000018682535,0.0000010020906,0.00011466826],"genre_scores_gemma":[0.9995267,0.0001518035,0.0001735846,0.000017558887,0.000113449685,2.2488307e-7,9.973941e-7,0.0000049248697,0.000010795342],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999501,0.00002824395,0.00020949013,0.000085300024,0.000052660755,0.00012329705],"domain_scores_gemma":[0.9996548,0.000017324039,0.00014475126,0.00008129923,0.000058188347,0.000043587883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003283158,0.00006912558,0.00016321107,0.00009455521,0.000027935312,0.0000018962696,0.00009256154,0.000112879745,0.0000048608695],"category_scores_gemma":[0.000038112095,0.00006349137,0.000051927862,0.00004856164,0.00006022284,0.0000042738816,0.00023659074,0.000097556454,1.8507936e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014623652,0.00002935882,0.17545433,0.000011504158,0.000021180185,0.000008581008,0.00007421935,0.00006172482,0.82246524,0.0000119621955,0.000025361162,0.0016902814],"study_design_scores_gemma":[0.0004907752,0.00036020184,0.7787678,0.0000105072995,0.000010410337,0.000087664004,0.00006266208,0.000008333637,0.21974899,0.00007551528,0.00031950272,0.00005760061],"about_ca_topic_score_codex":0.000032770415,"about_ca_topic_score_gemma":0.00006104663,"teacher_disagreement_score":0.6033135,"about_ca_system_score_codex":0.000019147905,"about_ca_system_score_gemma":0.000025105912,"threshold_uncertainty_score":0.25891027},"labels":[],"label_agreement":null},{"id":"W2169267824","doi":"10.1007/s10482-009-9397-5","title":"One gram of soil: a microbial biochemical gene library","year":2009,"lang":"en","type":"review","venue":"Antonie van Leeuwenhoek","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Gene; Microorganism; Soil water; Biology; DNA; Gram; Soil microbiology; Gene expression; Transcription (linguistics); DNA extraction; Bacteria; Environmental science; Genetics; Polymerase chain reaction; Ecology","score_opus":0.014233855680686889,"score_gpt":0.30071584892435743,"score_spread":0.2864819932436705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169267824","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011414074,0.9966945,0.0005522375,0.000020095562,0.00017229975,0.00038291776,0.00018041358,0.000042748467,0.00081338757],"genre_scores_gemma":[0.00064074533,0.9932606,0.002880373,0.00007554929,0.000700295,0.000021836819,0.0016567049,0.00011607328,0.00064781995],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99804246,0.000058900707,0.0006665585,0.00064155523,0.00015086403,0.0004396536],"domain_scores_gemma":[0.99883705,0.000019226947,0.00023939481,0.00071354443,0.000036162648,0.00015462897],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000088589324,0.0004939008,0.001143144,0.0001463431,0.000036701083,0.00003080894,0.0005135975,0.0006172059,0.00005664591],"category_scores_gemma":[0.00003115613,0.0005008836,0.00068712997,0.00023737802,0.00010306764,0.0000046336895,0.00021442406,0.00027561284,0.00003257044],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023537423,0.00023909597,0.000002640766,0.0046609817,0.00041098546,0.0000149846,0.000020391626,0.00001659728,0.11221654,0.000027647537,0.0079712,0.8743954],"study_design_scores_gemma":[0.0002391455,0.00021537847,0.00000450523,0.0013786013,0.00033618588,0.00006318715,0.0000024529047,0.0000028706897,0.14250907,0.000026073689,0.85470223,0.0005203154],"about_ca_topic_score_codex":0.000005863452,"about_ca_topic_score_gemma":0.0000016440123,"teacher_disagreement_score":0.8738751,"about_ca_system_score_codex":0.000011830028,"about_ca_system_score_gemma":0.0002618266,"threshold_uncertainty_score":0.9997443},"labels":[],"label_agreement":null},{"id":"W2170222722","doi":"10.1073/pnas.0609277104","title":"Developmental and adult phenotyping directly from mutant embryonic stem cells","year":2007,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":287,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Embryonic stem cell; Biology; Complementation; Mutant; Cell culture; Transgene; Embryo; Phenotype; Genetics; Cell biology; Genetically modified organism; Stem cell; Chimera (genetics); Transfection; Cell; Gene","score_opus":0.014653903282121341,"score_gpt":0.2838091588735833,"score_spread":0.269155255591462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170222722","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99818605,0.00036247534,0.000041113977,0.00013745921,0.000013406123,0.00005637343,0.000007397414,0.000002820366,0.001192899],"genre_scores_gemma":[0.99727815,0.000063708285,0.0024507986,0.00008936188,0.000056878922,0.000001158665,1.4287939e-7,0.00000275996,0.000057011097],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993312,0.0000011969099,0.00014181244,0.00015785254,0.00026794244,0.00010004046],"domain_scores_gemma":[0.99978274,0.0000185498,0.00009014486,0.0000033487836,0.00008098132,0.000024255389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039625482,0.000058098878,0.00006254654,0.000035607973,0.00007057686,0.000008802919,0.00021474778,0.000052561383,0.0000017760178],"category_scores_gemma":[0.000044972017,0.000043001677,0.000024557674,0.00012816384,0.00017561678,0.000007687138,0.00010011952,0.00004745687,2.4578063e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007703854,0.0000060528605,0.0015137258,0.000012074374,0.000009187718,2.3937063e-9,0.000071293485,0.000023311026,0.99626577,0.0004531793,0.000059634982,0.0015780653],"study_design_scores_gemma":[0.000092260525,0.000014392898,0.02027628,0.000025045896,0.0000040155446,0.000003133227,0.0002406073,0.0001772589,0.97834903,0.00047804997,0.00028447295,0.000055440716],"about_ca_topic_score_codex":0.0000039091865,"about_ca_topic_score_gemma":3.1033343e-7,"teacher_disagreement_score":0.018762555,"about_ca_system_score_codex":0.000008536707,"about_ca_system_score_gemma":0.000014599453,"threshold_uncertainty_score":0.17535575},"labels":[],"label_agreement":null},{"id":"W2170255645","doi":"10.1146/annurev.micro.112408.134123","title":"CRISPR/Cas System and Its Role in Phage-Bacteria Interactions","year":2010,"lang":"en","type":"review","venue":"Annual Review of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":620,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Trans-activating crRNA; Nucleic acid; Biology; Genetics; DNA; Bacteria; CRISPR interference; Palindrome; Computational biology; Genome; Genome editing; Gene","score_opus":0.008828353661266412,"score_gpt":0.34141362468212333,"score_spread":0.33258527102085694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170255645","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022662058,0.99804443,0.000040127616,0.000015626318,0.00041283274,0.0005897115,0.00044014148,0.00000823498,0.0002222444],"genre_scores_gemma":[0.00038417068,0.998273,0.00014655215,0.000061441315,0.00016494289,0.00007745401,0.00069261977,0.00003757786,0.0001622228],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983624,0.00017141706,0.0007396738,0.00044598934,0.000026054056,0.00025441637],"domain_scores_gemma":[0.99915636,0.000038452683,0.00028680728,0.00036344363,0.000093998184,0.000060923252],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030388104,0.00034830038,0.0013512028,0.000106160915,0.000021230619,0.0000054040097,0.0002614073,0.00041920683,0.000028028351],"category_scores_gemma":[0.00011882911,0.00029257883,0.00027743395,0.0001106315,0.000049434424,0.0000033606216,0.0002060623,0.00035225227,0.000025440171],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008510064,0.00006157979,0.000002797682,0.1794004,0.0001787859,0.000010879716,0.000048008525,2.47852e-7,0.14903614,0.00006896667,0.0017240712,0.66945964],"study_design_scores_gemma":[0.000095889714,0.00007579739,0.0000023929142,0.029675381,0.00019728941,0.00062155665,0.000023239396,3.110482e-7,0.003952457,3.2432507e-7,0.9651172,0.00023816935],"about_ca_topic_score_codex":0.000008037945,"about_ca_topic_score_gemma":0.00003363298,"teacher_disagreement_score":0.9633931,"about_ca_system_score_codex":0.000019113379,"about_ca_system_score_gemma":0.00009868468,"threshold_uncertainty_score":0.9999526},"labels":[],"label_agreement":null},{"id":"W2170332083","doi":"10.1007/978-1-4939-2877-4_15","title":"Selection and Validation of Spacer Sequences for CRISPR-Cas9 Genome Editing and Transcription Regulation in Bacteria","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke","keywords":"CRISPR; Palindrome; Cas9; Computational biology; Genome editing; Genome; Biology; Guide RNA; Transcription (linguistics); Genetics; Selection (genetic algorithm); RNA; Bacterial genome size; Gene; Computer science; Artificial intelligence","score_opus":0.02778354652393486,"score_gpt":0.4099826457558692,"score_spread":0.3821990992319343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170332083","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47975025,0.00043618897,0.5195777,0.0000368776,0.000060427334,0.00012065316,0.0000027113715,0.0000022414104,0.000012974819],"genre_scores_gemma":[0.6480275,0.000050190843,0.3517777,0.000012883389,0.000044480916,0.000023264167,0.000049908198,0.000007701417,0.0000063802627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991973,0.00021826489,0.00020117026,0.00023080563,0.000027576973,0.00012484862],"domain_scores_gemma":[0.999775,0.000019411162,0.00005443396,0.00007067904,0.000050969324,0.000029519657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086837687,0.00008746751,0.00013927974,0.00010483899,0.000012066921,0.0000065929,0.000030246354,0.00015578553,0.0000013469042],"category_scores_gemma":[0.00019933526,0.000092339746,0.000020559371,0.00008709137,0.000039740742,0.0000045782704,0.000019782443,0.00004474932,3.4484536e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004019004,0.000007723117,0.0033423752,0.000029970213,0.000007592451,1.7648624e-7,0.00014401722,0.0011017462,0.9917778,0.0001461567,0.0000013735535,0.003400918],"study_design_scores_gemma":[0.0005523274,0.00024611584,0.007402843,0.0000100075995,0.0000103897955,0.000010444415,0.000108046945,0.0022076555,0.98688465,0.0019690082,0.0005005627,0.00009793193],"about_ca_topic_score_codex":0.000032848926,"about_ca_topic_score_gemma":0.000036439455,"teacher_disagreement_score":0.16827723,"about_ca_system_score_codex":0.000013336048,"about_ca_system_score_gemma":0.000017584018,"threshold_uncertainty_score":0.37655056},"labels":[],"label_agreement":null},{"id":"W2171069705","doi":"10.1534/genetics.106.068106","title":"The<i>flamenco</i>Locus Controls the<i>gypsy</i>and<i>ZAM</i>Retroviruses and Is Required for Drosophila Oogenesis","year":2007,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"European Commission; Association pour la Recherche sur le Cancer","keywords":"Biology; Genetics; Transposable element; Locus (genetics); Heterochromatin; Mutant; Gene; Chromosome","score_opus":0.009824173504563475,"score_gpt":0.2930105328250991,"score_spread":0.2831863593205356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171069705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93348444,0.035216246,0.02830564,0.0015170511,0.00032251986,0.00072108733,0.000092628456,0.000023886536,0.00031651327],"genre_scores_gemma":[0.9913066,0.004649019,0.0019278158,0.001017653,0.0005241602,0.00004755884,0.000012537823,0.000042553642,0.00047209192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875367,0.000022283559,0.00028636752,0.00035114711,0.00014130694,0.00044522912],"domain_scores_gemma":[0.99911904,0.00014163414,0.00007420091,0.00045726576,0.00008736175,0.000120522986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000464164,0.00021855842,0.00015969898,0.000025053208,0.00034064025,0.00008244882,0.00022005606,0.00013971742,0.0000016500609],"category_scores_gemma":[0.00009177811,0.00015607274,0.00008848846,0.00006939474,0.0002231751,0.0000023113266,0.00013707715,0.00006899054,0.0000018916633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000150357,0.00001620344,0.0021912507,0.000028621247,0.000109772685,0.000001638601,0.00013290253,0.00006575587,0.9621539,0.000346432,0.0030504158,0.031752728],"study_design_scores_gemma":[0.0009291443,0.00034206975,0.004431145,0.000008482072,0.0000808138,0.00003783946,0.00018183251,0.00014805885,0.5952792,0.000409204,0.39786404,0.00028818264],"about_ca_topic_score_codex":0.000007550151,"about_ca_topic_score_gemma":0.00010937522,"teacher_disagreement_score":0.39481363,"about_ca_system_score_codex":0.0000072160565,"about_ca_system_score_gemma":0.00003075187,"threshold_uncertainty_score":0.6364461},"labels":[],"label_agreement":null},{"id":"W2173203512","doi":"10.1093/nar/gkv1261","title":"Foreign DNA acquisition by the I-F CRISPR–Cas system requires all components of the interference machinery","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Russian Science Foundation; National Institutes of Health; Russian Foundation for Basic Research","keywords":"CRISPR; Biology; DNA; Priming (agriculture); Trans-activating crRNA; RNA; Adaptation (eye); Computational biology; CRISPR interference; Genetics; Cas9; Gene","score_opus":0.051241372872502994,"score_gpt":0.3625482874433394,"score_spread":0.31130691457083637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2173203512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98937094,0.0010878202,0.0036923673,0.00036133206,0.00015537292,0.00029320983,0.00003675866,0.000013195427,0.004989013],"genre_scores_gemma":[0.99916416,0.000037677983,0.00007938204,0.000056440298,0.00012593991,0.00002356099,0.00004395508,0.000021033036,0.00044783886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985628,0.00023934807,0.00020304257,0.00023395906,0.00045376347,0.00030704951],"domain_scores_gemma":[0.9990133,0.000034038403,0.00004371592,0.0006071332,0.00021003866,0.00009179246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091207825,0.00011267665,0.00011378602,0.00003646057,0.00010601405,0.000035288307,0.00067524286,0.00010759277,0.000006289222],"category_scores_gemma":[0.000117911084,0.000068228284,0.000071507435,0.00013808734,0.00020548787,0.000004573774,0.00048272216,0.00021523946,0.000024075896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009834317,0.00003473036,0.0015216972,0.000056166227,0.00004231118,0.0000013746546,0.00021294851,0.00010043271,0.97112894,0.00037381315,0.025711566,0.0007177047],"study_design_scores_gemma":[0.00070277345,0.00043887476,0.0071011703,0.00011282407,0.000018299104,0.00004891978,0.0019322726,0.0031372695,0.9711707,0.00022925067,0.014917813,0.00018983075],"about_ca_topic_score_codex":0.0001863894,"about_ca_topic_score_gemma":0.000013495244,"teacher_disagreement_score":0.010793752,"about_ca_system_score_codex":0.00004718706,"about_ca_system_score_gemma":0.000044016044,"threshold_uncertainty_score":0.27822688},"labels":[],"label_agreement":null},{"id":"W2173518829","doi":"10.1038/mt.2015.185","title":"Gene Editing and Germ-line Intervention: The Need for Novel Responses to Novel Technologies","year":2015,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Wellcome Trust","keywords":"CRISPR; Scopus; Genome editing; Germline; Genetics; Gene; Biology; Political science; MEDLINE; Law","score_opus":0.025315755379856572,"score_gpt":0.32133365713253975,"score_spread":0.29601790175268317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2173518829","genre_codex":"methods","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07226695,0.016657142,0.6470152,0.261519,0.0007083543,0.0013768758,0.00030782656,0.000111558016,0.000037053687],"genre_scores_gemma":[0.27008882,0.002029788,0.07776407,0.6212611,0.01417993,0.002549991,0.0033120268,0.00088293443,0.007931351],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986852,0.000028183642,0.0002604836,0.00049814885,0.00018128316,0.00034674403],"domain_scores_gemma":[0.99905163,0.000031913332,0.000096912045,0.0006140952,0.00016616052,0.00003929068],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033391803,0.00033517883,0.00025819562,0.00010343873,0.000083943705,0.00007444195,0.00041285445,0.0005503332,0.0000025913466],"category_scores_gemma":[0.00020872457,0.0002645743,0.00018619226,0.00010085548,0.00008134,0.0000020473335,0.00019951948,0.0003321054,0.0000021234728],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012647088,0.000030109513,0.0000043070377,0.000036774654,0.00017122527,0.000009445851,0.000039806207,0.00008923679,0.90152085,0.000007846218,0.08865343,0.009310506],"study_design_scores_gemma":[0.00086633256,0.00033690297,0.000007903302,0.000027194994,0.000020768639,0.000040588915,0.000054710334,0.000045346645,0.42322853,0.00004602154,0.575097,0.00022868732],"about_ca_topic_score_codex":0.000008653957,"about_ca_topic_score_gemma":0.0000031744778,"teacher_disagreement_score":0.5692512,"about_ca_system_score_codex":0.000016279071,"about_ca_system_score_gemma":0.000041229072,"threshold_uncertainty_score":0.9999806},"labels":[],"label_agreement":null},{"id":"W2174285875","doi":"10.1051/medsci/20153111016","title":"CRISPR, un système qui permet de corriger ou de modifier l’expression de gènes responsables de maladies héréditaires","year":2015,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Molecular biology; Physics; Biology","score_opus":0.037310100279809084,"score_gpt":0.3657102971406561,"score_spread":0.32840019686084704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2174285875","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0884994,0.8900283,0.017913837,0.00041029984,0.00076064025,0.00046483777,0.0001400282,0.000052725496,0.0017299257],"genre_scores_gemma":[0.17846382,0.79532063,0.018173829,0.00035801978,0.0015657207,0.00022542682,0.00010142931,0.00013157407,0.0056595732],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952337,0.00073339336,0.0007552754,0.0011052615,0.00052295136,0.0016493746],"domain_scores_gemma":[0.9980292,0.00027433995,0.0003052724,0.00065451243,0.00018495132,0.00055176974],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003275905,0.0008241029,0.001072008,0.00026115103,0.00060180464,0.0002512495,0.0012676299,0.0008748391,0.00019287183],"category_scores_gemma":[0.0010692562,0.0006944971,0.000469962,0.00044851034,0.0009036885,0.000024090066,0.00043368308,0.00041221394,0.000058896316],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066796475,0.0017276276,0.060168583,0.02897764,0.0013905913,0.00094719103,0.0048686704,0.09029335,0.35122326,0.0054654917,0.15025866,0.30401096],"study_design_scores_gemma":[0.0012375839,0.0014737227,0.0028657382,0.010108327,0.0009855933,0.0020259356,0.002446094,0.0066256453,0.06847563,0.003187663,0.898053,0.0025150988],"about_ca_topic_score_codex":0.00027849854,"about_ca_topic_score_gemma":0.00008115979,"teacher_disagreement_score":0.74779433,"about_ca_system_score_codex":0.0003809683,"about_ca_system_score_gemma":0.0024561072,"threshold_uncertainty_score":0.99955064},"labels":[],"label_agreement":null},{"id":"W2180291937","doi":"10.1016/j.cell.2015.11.015","title":"High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1790,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; Canadian Institute for Advanced Research; Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biology; CRISPR; Gene; Computational biology; Genetics; Genetic Fitness; Context (archaeology); Cas9; Genome","score_opus":0.016166198912268316,"score_gpt":0.26933574615055217,"score_spread":0.25316954723828383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2180291937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.943219,0.048155703,0.0075358544,0.000102531616,0.0003637863,0.00010040967,0.000024689483,0.000016467675,0.0004815255],"genre_scores_gemma":[0.9931504,0.0025409057,0.0017580664,0.000042199154,0.00050992885,0.000017235554,0.000043249314,0.000018977911,0.0019190224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938726,0.000018629107,0.000105609404,0.00023637903,0.0000754009,0.00017672623],"domain_scores_gemma":[0.9995903,0.0000041713747,0.000022020859,0.00020501974,0.000078867924,0.00009964345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000093740426,0.00011080259,0.000094291725,0.000022838276,0.00003926162,0.000018070767,0.00007463119,0.00009223744,0.000009062838],"category_scores_gemma":[0.000010967028,0.000107894084,0.00002788739,0.000043279982,0.000052694446,0.0000025931226,0.00006972194,0.00004683055,0.0000058988567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066377535,0.000032307908,0.0021692412,0.000091575974,0.000019122963,0.0000036911795,0.00023760153,0.006316714,0.9699049,0.000079133686,0.016737,0.0043423623],"study_design_scores_gemma":[0.00059192884,0.00013968484,0.0043345224,0.000018431712,0.000017031569,0.000007133061,0.00024001945,0.00022037042,0.8874544,0.00011188705,0.1066028,0.00026180362],"about_ca_topic_score_codex":0.00014038479,"about_ca_topic_score_gemma":0.000062798994,"teacher_disagreement_score":0.0898658,"about_ca_system_score_codex":0.000013845491,"about_ca_system_score_gemma":0.000038752765,"threshold_uncertainty_score":0.43997929},"labels":[],"label_agreement":null},{"id":"W2180359111","doi":"10.1101/sqb.2015.80.027326","title":"Biological Networks Governing the Acquisition, Maintenance, and Dissolution of Pluripotency: Insights from Functional Genomics Approaches","year":2015,"lang":"en","type":"review","venue":"Cold Spring Harbor Symposia on Quantitative Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Stem Cell Network","keywords":"Functional genomics; Computational biology; Genomics; Biology; Throughput; Genome; Computer science; Genetics; Gene","score_opus":0.050801041793605096,"score_gpt":0.3110234279682748,"score_spread":0.2602223861746697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2180359111","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031162682,0.96013975,0.03563441,0.00001919748,0.00044025297,0.000426577,0.00014047454,0.000014823295,0.00006822497],"genre_scores_gemma":[0.041188143,0.9570617,0.0008981883,0.000037177506,0.00039388787,0.0000973305,0.00026743935,0.000040636536,0.000015471574],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99831104,0.0002721829,0.00045694417,0.00061363686,0.00008503599,0.00026115734],"domain_scores_gemma":[0.9989345,0.00019189183,0.0003439293,0.00035415808,0.00009527059,0.000080240214],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026002893,0.0003813078,0.00073943817,0.00006521345,0.000106666615,0.000019146242,0.00024941997,0.00051128055,0.0000028371426],"category_scores_gemma":[0.00010250522,0.00025589793,0.00020466451,0.00011380287,0.000324146,0.0000036899498,0.0002076895,0.0002717538,0.000005481593],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024063756,0.00011088953,0.0001506459,0.00055953796,0.00094282645,0.0000039280358,0.00007438963,0.0016986099,0.014886302,0.9672099,0.0002046483,0.013917731],"study_design_scores_gemma":[0.00026926285,0.0005134145,0.0008109494,0.00055035687,0.00017195576,0.0000019403935,0.000031402844,0.00085258734,0.00019247415,0.000065533946,0.99618524,0.00035489764],"about_ca_topic_score_codex":0.000017286082,"about_ca_topic_score_gemma":0.0000053086774,"teacher_disagreement_score":0.99598056,"about_ca_system_score_codex":0.000063635925,"about_ca_system_score_gemma":0.00011778277,"threshold_uncertainty_score":0.99998933},"labels":[],"label_agreement":null},{"id":"W2180640939","doi":"10.1038/527446b","title":"Gene editing: Govern ability expectations","year":2015,"lang":"en","type":"letter","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Genome editing; Computational biology; Gene; Biology; Computer science; Data science; Genetics; Genome","score_opus":0.006386463961730657,"score_gpt":0.28761934454502647,"score_spread":0.2812328805832958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2180640939","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04997179,0.07556717,0.0054652495,0.82682675,0.013993445,0.001462382,0.0023674958,0.0003001773,0.024045544],"genre_scores_gemma":[0.27503243,0.00017777954,0.004608702,0.61132085,0.07923274,0.00012483668,0.014210925,0.00026922332,0.015022485],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989041,0.000026649242,0.00014595807,0.00041607188,0.00026060716,0.00024658963],"domain_scores_gemma":[0.999202,0.000010477223,0.00006074669,0.00050862425,0.0001628735,0.000055279543],"candidate_categories":["research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0000763475,0.00022462627,0.0001625004,0.000029433408,0.00003703997,0.000023820694,0.00024632923,0.0044819918,0.000025659818],"category_scores_gemma":[0.00020065559,0.00022237854,0.00012449168,0.00006030513,0.000031469528,0.0000011713925,0.000087913366,0.0031003281,0.000021739683],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000031619622,0.0000066888842,0.000033805292,0.0000328815,0.00003646945,0.000015579199,0.000029565279,0.000029804469,0.01678807,6.855153e-7,0.98276395,0.0002593166],"study_design_scores_gemma":[0.00015142479,0.00003913675,0.000085745065,0.000008532314,0.000025700818,0.000020969757,0.000033854085,0.000011139411,0.03470745,0.00003642869,0.96464866,0.00023096189],"about_ca_topic_score_codex":0.0000038840135,"about_ca_topic_score_gemma":0.000008287195,"teacher_disagreement_score":0.22506064,"about_ca_system_score_codex":0.000033388536,"about_ca_system_score_gemma":0.0000905175,"threshold_uncertainty_score":0.99919957},"labels":[],"label_agreement":null},{"id":"W2181342396","doi":"10.3389/fmicb.2015.01244","title":"Inside the Envelope: Endogenous Retrovirus-K Env as a Biomarker and Therapeutic Target","year":2015,"lang":"en","type":"review","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Winnipeg","funders":"University of Winnipeg","keywords":"Endogenous retrovirus; Biology; Epigenetics; Innate immune system; Biomarker; Virology; Disease; Gene silencing; Retrovirus; Genome; Genetics; Gene; Immunology; Immune system; Virus; Medicine","score_opus":0.027276230207950974,"score_gpt":0.30678718589848825,"score_spread":0.2795109556905373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181342396","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017821464,0.99642235,0.0011270414,0.000025710262,0.00096835796,0.00060544326,0.00009158614,0.000011437559,0.00056987227],"genre_scores_gemma":[0.00061454833,0.9963144,0.0016589841,0.00021449754,0.00016426585,0.00008625192,0.00047020375,0.0000677543,0.0004090863],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99815494,0.00031077795,0.0004318899,0.00060222857,0.00004366358,0.00045651585],"domain_scores_gemma":[0.9991831,0.000026991458,0.00013890384,0.00053171685,0.00004296496,0.00007628165],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045602035,0.00045178898,0.0009275765,0.00015080403,0.00006094522,0.000021770913,0.0004422371,0.0006987666,0.000015020998],"category_scores_gemma":[0.0000751848,0.00031886995,0.00016785234,0.00019690763,0.00025849746,0.000001368011,0.00027165818,0.00034662237,0.000017452152],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055726116,0.000041402403,0.00016046394,0.0010699357,0.0006937969,0.00004162777,0.00016984835,0.0000060858424,0.021431081,0.000011468428,0.032373864,0.9439447],"study_design_scores_gemma":[0.00026117568,0.00012616006,0.0000061252995,0.00017365563,0.00013570962,0.00069874775,0.000051651547,0.00000327985,0.00064309296,0.000063118874,0.99746734,0.00036996702],"about_ca_topic_score_codex":0.000019487543,"about_ca_topic_score_gemma":0.000012126163,"teacher_disagreement_score":0.96509343,"about_ca_system_score_codex":0.000058259226,"about_ca_system_score_gemma":0.00031259915,"threshold_uncertainty_score":0.9999263},"labels":[],"label_agreement":null},{"id":"W2181403855","doi":"","title":"Targeted Genome Editing for Gene Containment in Transgenic Black Ash","year":2013,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biology; Emerald ash borer; Agrobacterium; Genome; Gene; Transgene; Genetically modified crops; Botany; Genetics; Fraxinus","score_opus":0.005672945129152168,"score_gpt":0.2568902712464876,"score_spread":0.25121732611733544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181403855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8999673,0.0003971108,0.09828642,0.00016638929,0.00008718837,0.00048173487,0.000009591807,0.000011685141,0.00059257343],"genre_scores_gemma":[0.9940837,0.00005287578,0.0044464194,0.00017710782,0.00025753814,0.00011636044,0.000107689535,0.000019004885,0.0007392948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999298,0.000008179025,0.00017284632,0.00021417612,0.00005192743,0.0002548917],"domain_scores_gemma":[0.9997396,0.000005005904,0.00001754731,0.0001453921,0.000034041932,0.000058414098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008602911,0.000106425265,0.00009903819,0.000028050337,0.00001949368,0.000013945484,0.00009031903,0.00008013011,0.00011773918],"category_scores_gemma":[0.000015431908,0.00010375316,0.00006543328,0.000037453,0.000016587052,0.000001799052,0.00002327025,0.000037057463,0.000015481235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006955536,0.000018233632,0.0003483779,0.000015383128,0.000019018953,2.4818837e-7,0.00006901148,0.0018060493,0.99655044,0.00001358024,0.00046648388,0.0006862234],"study_design_scores_gemma":[0.0010407886,0.00018329988,0.0101511255,0.000004112004,0.0000067953897,0.0000020646617,0.00031011048,0.0018026709,0.9732926,0.000068489906,0.012911984,0.0002259476],"about_ca_topic_score_codex":0.000029185547,"about_ca_topic_score_gemma":0.00004986976,"teacher_disagreement_score":0.0941164,"about_ca_system_score_codex":0.000012379611,"about_ca_system_score_gemma":0.000014722645,"threshold_uncertainty_score":0.4230931},"labels":[],"label_agreement":null},{"id":"W2186989880","doi":"10.1038/nature15254","title":"Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins","year":2015,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":377,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"CRISPR; Biology; CRISPR interference; Trans-activating crRNA; DNA; Nuclease; Gene; Computational biology; Genetics; Cas9; Cell biology","score_opus":0.007571097082585725,"score_gpt":0.292831508309048,"score_spread":0.2852604112264623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2186989880","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.29059494,0.0047821044,0.7015921,0.000765678,0.0006943749,0.00094379194,0.00023443019,0.00006230069,0.0003302876],"genre_scores_gemma":[0.9884163,0.000028599383,0.009673627,0.00047730294,0.00028098235,0.00007992097,0.0005012191,0.00003228478,0.000509776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992421,0.000012820281,0.00011568912,0.00028180747,0.00012788712,0.00021967916],"domain_scores_gemma":[0.9994947,0.000006415104,0.00003403547,0.00021536397,0.00014382844,0.0001056897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326278,0.00014282386,0.000109713845,0.000027178517,0.000046708094,0.000023591754,0.000094326206,0.00083889405,0.0000037994153],"category_scores_gemma":[0.00020338477,0.00013705941,0.00007199394,0.000058468566,0.000014299213,0.000003886928,0.00004848729,0.0003267122,0.000005076667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039886734,0.000037628615,0.000066115164,0.000024166071,0.000016663495,0.0000012684184,0.0000357428,0.00012127151,0.9345221,0.00012732566,0.064425595,0.00058225374],"study_design_scores_gemma":[0.0008482081,0.00020776816,0.00008075037,0.000009079901,0.00001126987,0.000008651511,0.000057070323,0.0003333569,0.87569505,0.000331984,0.122247145,0.00016963868],"about_ca_topic_score_codex":0.000007738574,"about_ca_topic_score_gemma":0.000018896662,"teacher_disagreement_score":0.6978213,"about_ca_system_score_codex":0.000014886255,"about_ca_system_score_gemma":0.00003480295,"threshold_uncertainty_score":0.6470319},"labels":[],"label_agreement":null},{"id":"W2187167030","doi":"10.1101/021121","title":"Genome Editing in <i>Caenorhabditis briggsae</i> using the CRISPR/Cas9 System","year":2015,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Caenorhabditis elegans; Caenorhabditis; Genome editing; Genetics; Biology; Cas9; Genome; Computational biology; Gene","score_opus":0.012446617407324185,"score_gpt":0.25053783555224146,"score_spread":0.23809121814491727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2187167030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9726925,0.007832793,0.016097194,0.00007740785,0.0021248222,0.0007656115,0.00023521362,0.00013505491,0.000039388997],"genre_scores_gemma":[0.99437433,0.0001990837,0.0024319761,0.00009652258,0.0025967867,0.00011808199,0.0000023379387,0.0001754207,0.0000054806787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99705136,0.00016275734,0.00064287183,0.0010308266,0.0003687156,0.00074344577],"domain_scores_gemma":[0.9975405,0.00002019694,0.0003077379,0.0014942937,0.00039072943,0.00024657926],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010105715,0.00061138027,0.0005316366,0.00016545561,0.00015418776,0.0001925509,0.000792166,0.0006624002,0.0000057746824],"category_scores_gemma":[0.0001719673,0.00059547724,0.00018744734,0.0003265938,0.000107878106,0.000009270462,0.0009050032,0.0007147544,0.000014476055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016016904,0.000037577316,0.0021210867,0.0004177195,0.00010397349,0.00006639559,0.000015962183,0.010557751,0.9863727,0.00004114091,0.00024795427,0.0000017111537],"study_design_scores_gemma":[0.0015305533,0.00014612568,0.029159848,0.0012040689,0.00030443128,0.0000015476826,0.00012734442,0.007879118,0.9227058,0.0000018225038,0.034473587,0.002465724],"about_ca_topic_score_codex":0.00015130534,"about_ca_topic_score_gemma":0.000017056253,"teacher_disagreement_score":0.06366688,"about_ca_system_score_codex":0.0002991472,"about_ca_system_score_gemma":0.00053660007,"threshold_uncertainty_score":0.99964964},"labels":[],"label_agreement":null},{"id":"W2190526372","doi":"10.1890/es15-00304.1","title":"Experimental assessment of gene flow between transgenic squash and a wild relative in the center of origin of cucurbits","year":2015,"lang":"en","type":"article","venue":"Ecosphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg","funders":"","keywords":"Biology; Backcrossing; Hybrid; Introgression; Transgene; Genetics; Cucurbita pepo; Zucchini yellow mosaic virus; Gene flow; Cucurbita; Biosafety; Botany; Gene; Plant virus; Biotechnology; Virus; Genetic variation; Potyvirus","score_opus":0.01833418755273934,"score_gpt":0.33041376009203116,"score_spread":0.3120795725392918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2190526372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99305236,0.0017156667,0.0032901545,0.000019826508,0.000029027686,0.00011752873,0.000030933767,0.0000010646665,0.001743423],"genre_scores_gemma":[0.9965113,0.000034928147,0.0033539252,0.000006733102,0.000028799377,0.0000058923933,0.000022853952,0.0000068656354,0.000028734648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995212,0.000031666652,0.00017666763,0.00010635186,0.00008541739,0.00007868179],"domain_scores_gemma":[0.999761,0.000009316543,0.00004669355,0.00013245638,0.000024015768,0.000026535794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012842267,0.00007040497,0.00013183277,0.000008951831,0.000005532937,0.0000017067805,0.00008304127,0.000052727148,0.000012716546],"category_scores_gemma":[0.000006186606,0.00005625197,0.000039651768,0.00005031114,0.000033865796,0.0000025564705,0.000021038837,0.000044605298,2.410478e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006105606,0.00027677903,0.09593983,0.00009372637,0.0001515898,0.0000013322698,0.0030537331,0.0017819917,0.8958093,0.00010099155,0.0011623186,0.0015673859],"study_design_scores_gemma":[0.0012562969,0.0005007817,0.04435934,0.00003052092,0.00001860977,0.0000025753395,0.0007809946,0.0003924713,0.9514415,0.000025312089,0.0010990384,0.00009254943],"about_ca_topic_score_codex":0.000020260604,"about_ca_topic_score_gemma":0.000026102229,"teacher_disagreement_score":0.05563224,"about_ca_system_score_codex":0.0000062686704,"about_ca_system_score_gemma":0.00003040872,"threshold_uncertainty_score":0.22938888},"labels":[],"label_agreement":null},{"id":"W2190856209","doi":"10.1016/j.celrep.2015.11.021","title":"Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canadian Institute for Advanced Research","funders":"National Science Foundation Graduate Research Fellowship Program; National Science Foundation; Cancer Research UK; National Cancer Institute; National Science Council; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"CRISPR; Glioblastoma; Wee1; Genome editing; Biology; Redundancy (engineering); Genome; Stem cell; Computational biology; Genetics; Gene; Cancer research; Computer science; Cell cycle","score_opus":0.010512676392270836,"score_gpt":0.25854022801122006,"score_spread":0.24802755161894924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2190856209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939645,0.0027779834,0.0016341963,0.000024431803,0.0001948663,0.0001987334,0.000010123543,0.000011124857,0.001184072],"genre_scores_gemma":[0.9974166,0.000122026395,0.0005073582,0.000024077835,0.0001416404,0.0000069500093,0.000020305402,0.00003208333,0.0017289417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986096,0.000032071523,0.000492387,0.00041616987,0.00016628254,0.0002835018],"domain_scores_gemma":[0.99905926,0.000014388478,0.0001666057,0.00047262223,0.00008811037,0.00019903838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034921002,0.00018418845,0.00027371748,0.000079713485,0.00002199854,0.000013615341,0.00009548263,0.00016888785,0.000004666787],"category_scores_gemma":[0.000034339002,0.00019402106,0.000063764295,0.00010874524,0.00007145097,0.0000043325963,0.00014655548,0.00010601333,0.0000024861245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006275258,0.00007458528,0.21678697,0.00018815108,0.000042434207,0.00046613303,0.00031342084,0.0008536425,0.7779816,9.410783e-7,0.0023351372,0.0008942794],"study_design_scores_gemma":[0.00045648532,0.00034217746,0.030213527,0.00003480414,0.000031385152,0.000111591224,0.0001645607,0.000010768815,0.9431107,0.00003744513,0.025204957,0.0002816199],"about_ca_topic_score_codex":0.000041270247,"about_ca_topic_score_gemma":0.00003191168,"teacher_disagreement_score":0.18657343,"about_ca_system_score_codex":0.00001806797,"about_ca_system_score_gemma":0.00008717166,"threshold_uncertainty_score":0.7911949},"labels":[],"label_agreement":null},{"id":"W2193229373","doi":"10.1016/j.celrep.2015.11.048","title":"Quantification of Protein Levels in Single Living Cells","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Biology; Phenotype; Gene; Translation (biology); Protein subcellular localization prediction; Green fluorescent protein; Endogeny; Computational biology; Molecular biology; Messenger RNA; Genetics; Biochemistry","score_opus":0.02503143478616855,"score_gpt":0.2794198344853145,"score_spread":0.25438839969914595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2193229373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98701847,0.0005828583,0.009796372,0.000005825904,0.00012401314,0.00012553159,7.6558985e-7,0.0000050839885,0.0023410842],"genre_scores_gemma":[0.997808,0.0000033070057,0.0011644162,0.0000041004587,0.0000367234,0.000007702021,0.0000070419414,0.000010127061,0.0009586022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994361,0.0000135538885,0.00021639973,0.0001643961,0.00007364615,0.00009589631],"domain_scores_gemma":[0.99957776,0.0000034177365,0.000084143365,0.00024452596,0.000048902464,0.000041231844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023463306,0.000058921505,0.00007307168,0.000029388673,0.000005907728,0.0000052866117,0.00003910483,0.000060170863,0.000004677477],"category_scores_gemma":[0.00008450044,0.00006254755,0.000024759947,0.000053544863,0.000013704971,0.0000014739567,0.000032280695,0.00002900546,0.0000015401515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000020598782,0.000052273135,0.0016962525,0.000023429013,0.0000017019017,0.0000095193245,0.00007300307,0.0018009591,0.99585825,0.0000014663818,0.00012260105,0.00035849467],"study_design_scores_gemma":[0.000053782067,0.000057806927,0.0021864625,0.00002288571,0.0000021592477,0.000010066173,0.00005786863,0.000057840076,0.9940257,0.000018240458,0.0034355787,0.000071591494],"about_ca_topic_score_codex":0.000019848585,"about_ca_topic_score_gemma":0.000012824852,"teacher_disagreement_score":0.0107895145,"about_ca_system_score_codex":0.000008553847,"about_ca_system_score_gemma":0.000043673386,"threshold_uncertainty_score":0.2550615},"labels":[],"label_agreement":null},{"id":"W2193280334","doi":"10.1016/j.ajhg.2015.11.012","title":"Spell Checking Nature: Versatility of CRISPR/Cas9 for Developing Treatments for Inherited Disorders","year":2015,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; National Institute for Health and Care Research","keywords":"CRISPR; Spell; Computer science; Computational biology; Medicine; Biology; Genetics; Philosophy","score_opus":0.025022627689148275,"score_gpt":0.3687674013515245,"score_spread":0.34374477366237627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2193280334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.921214,0.0018721754,0.07634162,0.0001328749,0.00015468648,0.0002278711,0.000015124915,0.0000023761995,0.000039314975],"genre_scores_gemma":[0.98189294,0.00021634872,0.01750614,0.00008206268,0.00021894801,0.000003590243,0.000013623646,0.000026303567,0.000040045605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991658,0.000036673744,0.00034283055,0.00012816284,0.0001347839,0.00019175884],"domain_scores_gemma":[0.99902016,0.000035126024,0.00038637265,0.00022403372,0.00026669112,0.000067629175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033515145,0.0001378164,0.00025068535,0.000046937177,0.00004701539,0.000011989028,0.00027806658,0.00005234278,8.959858e-7],"category_scores_gemma":[0.00009896144,0.00010757987,0.00016023587,0.0000878439,0.00014240906,0.0000026273563,0.000048705,0.000089438945,2.0712605e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016931698,0.0002650742,0.017049665,0.00013535109,0.0014366346,0.0000019276297,0.0023837234,0.0073351935,0.9220987,0.00013169627,0.0035849877,0.043883882],"study_design_scores_gemma":[0.003972029,0.007449926,0.022253493,0.000069191745,0.00046474393,0.00004023949,0.0030111987,0.00081398385,0.94071925,0.0020401282,0.018683193,0.00048261334],"about_ca_topic_score_codex":0.000006425173,"about_ca_topic_score_gemma":0.000015793888,"teacher_disagreement_score":0.06067898,"about_ca_system_score_codex":0.000028969998,"about_ca_system_score_gemma":0.000104912906,"threshold_uncertainty_score":0.43869796},"labels":[],"label_agreement":null},{"id":"W2193610513","doi":"10.1038/ncomms10124","title":"PAM multiplicity marks genomic target sites as inhibitory to CRISPR-Cas9 editing","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Guide RNA; Genome editing; Computational biology; Biology; DNA; RNA; Genetics; Gene","score_opus":0.01596522800154552,"score_gpt":0.3372317103344616,"score_spread":0.32126648233291605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2193610513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9454355,0.025284193,0.008985966,0.0044832677,0.00079866423,0.0006049651,0.00008896548,0.00011312162,0.014205303],"genre_scores_gemma":[0.9721814,0.00013134386,0.025704436,0.0008702758,0.00046958128,0.00004136473,0.0003016437,0.000026048223,0.0002739153],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99924296,0.000058201862,0.00017013187,0.00022290442,0.000107035135,0.00019874997],"domain_scores_gemma":[0.9983206,0.000032339463,0.000042347085,0.0012509265,0.00017346641,0.00018033267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022783972,0.00013560556,0.00010711555,0.000053646323,0.00013358904,0.000028493492,0.0006517732,0.00027857683,0.000008536916],"category_scores_gemma":[0.0004955922,0.0001458452,0.000052782114,0.0001144717,0.00004384581,0.000003970818,0.0006476464,0.00042207932,0.00004730974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022328913,0.00008799613,0.0066708596,0.000009610315,0.00004592135,0.0000011075839,0.00038334797,0.001419026,0.9064573,0.00026401647,0.083659805,0.0009786722],"study_design_scores_gemma":[0.0004299574,0.00013277825,0.008135374,0.000017465516,0.000022334476,0.000019068957,0.00046994293,0.0010611911,0.21430303,0.000109908986,0.7749381,0.0003608257],"about_ca_topic_score_codex":0.000024152554,"about_ca_topic_score_gemma":0.0002070572,"teacher_disagreement_score":0.6921543,"about_ca_system_score_codex":0.00003313293,"about_ca_system_score_gemma":0.00006688283,"threshold_uncertainty_score":0.5947395},"labels":[],"label_agreement":null},{"id":"W2197776587","doi":"10.1016/j.cels.2015.12.007","title":"Essential Human Genes","year":2015,"lang":"en","type":"article","venue":"Cell Systems","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Gene; Biology; Computational biology; Genetics; Evolutionary biology","score_opus":0.01210734472615451,"score_gpt":0.2883443225928416,"score_spread":0.2762369778666871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2197776587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96332026,0.007903976,0.0111276135,0.00000778671,0.0009802047,0.00012770836,0.000003638635,0.000023387649,0.016505413],"genre_scores_gemma":[0.9945416,0.000019206685,0.00006837468,0.000008518359,0.0007721539,0.000011070282,0.000038840055,0.000012773558,0.0045274864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999507,0.000017129723,0.00010616777,0.00015159028,0.000087498476,0.00013059397],"domain_scores_gemma":[0.99963224,0.0000011060956,0.000022964392,0.00020788517,0.000045189845,0.000090598456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010034463,0.000077486926,0.000073682226,0.000015874815,0.000027305901,0.00002302606,0.00009554001,0.00007898141,0.0000036500417],"category_scores_gemma":[0.000004779245,0.000075486154,0.0000335759,0.00002673186,0.000013796126,7.648219e-7,0.000041773717,0.000028803994,0.000031600455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034468176,0.000014361809,0.0007030962,0.000029421302,0.000009537152,0.0000024825217,0.00003464278,0.0023551078,0.9884956,0.000046999143,0.008197905,0.00010741071],"study_design_scores_gemma":[0.00039135336,0.00009468568,0.000117798976,0.0000060979883,0.000009495272,0.000015219833,0.00020339916,0.00025358258,0.7206195,0.00000495456,0.27812374,0.0001601654],"about_ca_topic_score_codex":0.00005087848,"about_ca_topic_score_gemma":0.0000062417507,"teacher_disagreement_score":0.26992583,"about_ca_system_score_codex":0.000005809049,"about_ca_system_score_gemma":0.000021013733,"threshold_uncertainty_score":0.3078236},"labels":[],"label_agreement":null},{"id":"W2197932059","doi":"","title":"Plant Introduction in India during Pre- and Post-CBD Periods–An Analysis","year":2006,"lang":"en","type":"article","venue":"Indian Journal of Plant Genetic Resources","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Germplasm; Plant quarantine; Quarantine; Agriculture; Geography; Socioeconomics; Veterinary medicine; Medicine; Biology; Ecology; Horticulture; Economics","score_opus":0.0018121702370777531,"score_gpt":0.2116864717824507,"score_spread":0.20987430154537295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2197932059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997274,0.0022111102,0.00020435586,0.00005277507,0.00009399922,0.00007590033,0.00006151254,0.000003572463,0.000022772669],"genre_scores_gemma":[0.9979491,0.00023024745,0.0006850526,0.000014737641,0.0009590739,0.0000022566403,0.00008155038,0.000014650458,0.00006332578],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988707,0.00006535028,0.00043192264,0.00023247312,0.00017092441,0.00022864187],"domain_scores_gemma":[0.9994745,0.000009804716,0.00018169158,0.00017684157,0.000046073186,0.00011105092],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021688583,0.00015330632,0.00023709965,0.00044992156,0.000057063135,0.00005956803,0.00016051934,0.00011382678,0.0000153162],"category_scores_gemma":[0.00002606297,0.00014073275,0.000087451015,0.0001783748,0.000046115194,0.0000074326035,0.00003565001,0.00014610596,5.340832e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031915298,0.00007874434,0.30135918,0.000046313213,0.00024098122,0.00028598733,0.001693426,0.0300256,0.6649327,0.000003065491,0.00008803123,0.0009268026],"study_design_scores_gemma":[0.000475518,0.00032202044,0.9498686,0.000018146722,0.000097693075,0.0012173977,0.00048128425,0.0001486962,0.045470033,0.0000065433405,0.001722329,0.00017171931],"about_ca_topic_score_codex":0.00009187571,"about_ca_topic_score_gemma":0.00027672865,"teacher_disagreement_score":0.64850944,"about_ca_system_score_codex":0.000015491312,"about_ca_system_score_gemma":0.000029664168,"threshold_uncertainty_score":0.5738915},"labels":[],"label_agreement":null},{"id":"W2199695484","doi":"10.1038/nrmicro3569","title":"An updated evolutionary classification of CRISPR–Cas systems","year":2015,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2570,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université Laval","funders":"Biotechnology and Biological Sciences Research Council; National Institutes of Health; National Institute of General Medical Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"CRISPR; Biology; Horizontal gene transfer; Computational biology; Genetics; Archaea; Locus (genetics); Phylogenetic tree; Evolutionary biology; Acquired immune system; Phylogenetics; Gene; Immune system","score_opus":0.028110412820760093,"score_gpt":0.39121463323362793,"score_spread":0.36310422041286783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2199695484","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000011336792,0.9957068,0.0015945868,0.0000057064053,0.0009364258,0.0011873154,0.00035574488,0.000019224783,0.00018284298],"genre_scores_gemma":[0.00022735617,0.9833512,0.000605194,0.000025173009,0.00053830806,0.00010221692,0.0148765,0.00006208011,0.00021200192],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973089,0.00060105766,0.0010211878,0.0007008768,0.00006194495,0.00030602544],"domain_scores_gemma":[0.99793696,0.000013281621,0.0006399667,0.001040966,0.00025382257,0.00011501133],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006554459,0.0005030787,0.0018679667,0.00015122328,0.00003380196,0.000010682979,0.0005843653,0.0022148234,0.000017861383],"category_scores_gemma":[0.000065344204,0.00039195103,0.00045000712,0.0002480607,0.00009465565,0.0000035298435,0.00010312884,0.00064537185,0.000049153066],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002889806,0.00021553549,0.000013497296,0.020791361,0.00049850845,0.000005432468,0.000020777077,0.000027576898,0.12279512,0.0003386068,0.18490705,0.67035764],"study_design_scores_gemma":[0.000112630245,0.00016247317,0.000003749799,0.0012768725,0.00037564983,0.00031714456,0.0000058284145,0.000006446353,0.0003193136,0.0000021038456,0.99704933,0.000368452],"about_ca_topic_score_codex":0.0000046066602,"about_ca_topic_score_gemma":0.000004405486,"teacher_disagreement_score":0.81214225,"about_ca_system_score_codex":0.00007161978,"about_ca_system_score_gemma":0.00028346395,"threshold_uncertainty_score":0.99985325},"labels":[],"label_agreement":null},{"id":"W2203752081","doi":"10.1016/b978-0-12-373932-2.00391-4","title":"Human Genome Project","year":2012,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Human genome; Engineering ethics; Ethical issues; Genome; Data science; Biology; Engineering; Genetics; Computer science; Gene","score_opus":0.014379934333182874,"score_gpt":0.2880035650651291,"score_spread":0.27362363073194623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2203752081","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004907287,0.008585285,0.00003656421,0.0000051676925,0.00019509096,0.00037655796,0.000035820554,0.000027745798,0.990247],"genre_scores_gemma":[0.0115113435,0.00020214467,0.0002647629,0.00009874782,0.0014839042,0.000031641677,0.00020548742,0.00012398837,0.98607796],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99892515,0.000008561758,0.0002465208,0.00037245656,0.00013624597,0.0003110536],"domain_scores_gemma":[0.9992044,0.0000020964512,0.00008642531,0.0005703408,0.000043263277,0.00009349832],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001093905,0.0003509909,0.00026029735,0.000071401366,0.000069489266,0.000019045181,0.00022254705,0.00040098923,0.00010749768],"category_scores_gemma":[0.0000038740664,0.00035420377,0.00020945902,0.000004660748,0.00006103677,7.5091646e-7,0.00017052596,0.0002142446,0.00007783356],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009203445,0.000011603652,0.000007068034,0.00014824951,0.00025311531,0.000009838286,0.00010123394,0.0000052130263,0.20676593,0.0009936792,0.0005638425,0.791131],"study_design_scores_gemma":[0.00014012567,0.000089552836,0.00005512065,0.00003805732,0.00007151395,0.000022667089,0.0000026477578,2.9174333e-7,0.0041871103,0.0001632033,0.994798,0.0004317238],"about_ca_topic_score_codex":3.3551368e-7,"about_ca_topic_score_gemma":0.000009960849,"teacher_disagreement_score":0.99423414,"about_ca_system_score_codex":0.000018588122,"about_ca_system_score_gemma":0.00005356523,"threshold_uncertainty_score":0.999891},"labels":[],"label_agreement":null},{"id":"W2204008251","doi":"10.1371/journal.pgen.1005699","title":"Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Canadian Institute for Advanced Research","keywords":"Inverted repeat; Biology; Genetics; Gene duplication; DNA; Computational biology; Genome; Gene","score_opus":0.06772455666639882,"score_gpt":0.3282154308808143,"score_spread":0.26049087421441547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2204008251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.716019,0.0011086162,0.28167835,0.00011111228,0.00014361681,0.0005638716,0.000084051,0.000033951837,0.00025745618],"genre_scores_gemma":[0.9891254,0.00014539929,0.009615738,0.00010766899,0.00016308046,0.000105123225,0.000298901,0.00004456689,0.0003941728],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880636,0.000020292664,0.00034297802,0.0003721512,0.00022330065,0.00023491503],"domain_scores_gemma":[0.9986764,0.00001465963,0.00011246867,0.000622195,0.00041077257,0.00016346037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014617958,0.00018395283,0.00017951167,0.00006198335,0.00003763394,0.000017976206,0.00025933015,0.0001638522,0.0000030653118],"category_scores_gemma":[0.00014900965,0.00019565459,0.000074341915,0.0001083082,0.000051554012,0.0000034744373,0.000072875504,0.000056325494,0.000007472623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005191674,0.00013316133,0.001635008,0.0000688812,0.00006848615,1.9025578e-7,0.0002190317,0.02442005,0.9701308,0.00013677005,0.0020351822,0.0011005303],"study_design_scores_gemma":[0.00067030324,0.00017855185,0.00028239278,0.00001222308,0.00006419024,0.0000039036518,0.000061107654,0.28729847,0.7082885,0.0004441839,0.0024763115,0.00021985902],"about_ca_topic_score_codex":0.0000037626442,"about_ca_topic_score_gemma":0.000033772107,"teacher_disagreement_score":0.27310637,"about_ca_system_score_codex":0.00002809472,"about_ca_system_score_gemma":0.00016378588,"threshold_uncertainty_score":0.7978563},"labels":[],"label_agreement":null},{"id":"W2207886346","doi":"10.1093/genetics/154.4.1561","title":"A Yeast taf17 Mutant Requires the Swi6 Transcriptional Activator for Viability and Shows Defects in Cell Cycle-Regulated Transcription","year":2000,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Activator (genetics); Mutant; Transcription (linguistics); Genetics; Yeast; Transcription factor; Cell cycle; Promoter; Cell biology; Gene; Gene expression","score_opus":0.007911987126296314,"score_gpt":0.24920159646440176,"score_spread":0.24128960933810545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2207886346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928686,0.0011916292,0.0050458433,0.000113018636,0.0000875026,0.0004454824,0.00007608641,0.000011303526,0.00016052021],"genre_scores_gemma":[0.99848646,0.00022112679,0.0007934631,0.00007517286,0.00012838245,0.00005881042,0.00005084749,0.00002268425,0.00016304757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991097,0.00003778807,0.00019901287,0.00029691303,0.00009463672,0.00026195013],"domain_scores_gemma":[0.999637,0.000012955714,0.000020947711,0.00023506391,0.000027229344,0.00006681424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158541,0.00015252984,0.00011455235,0.000024259938,0.000069545524,0.00002361794,0.00011260531,0.00013434223,0.00003694549],"category_scores_gemma":[0.000011411366,0.00013105659,0.00007798398,0.000052788368,0.000073457224,0.0000034105394,0.000011585025,0.00007479292,0.0000014961498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000115530725,0.000053741132,0.0004747409,0.000040354556,0.000012305719,4.911881e-7,0.00018220661,0.0041194144,0.9878905,0.000019062363,0.00006035021,0.0070313457],"study_design_scores_gemma":[0.0012706866,0.00029728303,0.027542327,0.000013566243,0.000038173228,0.000014936799,0.00009777478,0.004567545,0.9312993,0.0002697119,0.034323517,0.00026515673],"about_ca_topic_score_codex":0.000008938508,"about_ca_topic_score_gemma":0.00016610933,"teacher_disagreement_score":0.056591135,"about_ca_system_score_codex":0.000014074435,"about_ca_system_score_gemma":0.000034334083,"threshold_uncertainty_score":0.53443325},"labels":[],"label_agreement":null},{"id":"W2208298605","doi":"10.1038/mt.2015.190","title":"Silent IL2RG Gene Editing in Human Pluripotent Stem Cells","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Sunnybrook Hospital; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Induced pluripotent stem cell; Biology; Chromatin; Homologous recombination; Genetics; Gene targeting; Transgene; Genome editing; Gene knockin; Selectable marker; Human artificial chromosome; Gene; Retrotransposon; CRISPR; Cell biology; Genome; Embryonic stem cell; Transposable element; Chromosome","score_opus":0.015945645220276316,"score_gpt":0.2857658430656295,"score_spread":0.2698201978453532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2208298605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.978776,0.004134282,0.016147243,0.00007395993,0.00025499164,0.00019698635,0.000003983527,0.000019068091,0.0003935374],"genre_scores_gemma":[0.99831694,0.00014569882,0.0006618591,0.00027792642,0.00024251343,0.000027509066,0.00003078405,0.000040132498,0.00025662174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989782,0.000049979106,0.00020326325,0.00031280686,0.00017093495,0.00028481925],"domain_scores_gemma":[0.9994515,0.0000022235427,0.00003989684,0.00033857115,0.000048389047,0.00011942733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021066693,0.00017280478,0.00013716694,0.000055167275,0.000029283594,0.000023293547,0.00017927232,0.000109008244,0.0000074460395],"category_scores_gemma":[0.0000045399433,0.00017515973,0.000080490136,0.00008100945,0.000023383802,0.0000019842432,0.00006228324,0.00009083439,0.000009734865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001918845,0.000050796138,0.00022055127,0.000004352174,0.00002460534,0.00003289446,0.00013305509,0.007546382,0.9881886,0.000019382343,0.00023587409,0.0035242802],"study_design_scores_gemma":[0.0010828767,0.00021218408,0.00020323246,0.00000885267,0.000003380551,0.000008229172,0.000103255436,0.00017007085,0.9779712,0.00003913585,0.019999282,0.00019832239],"about_ca_topic_score_codex":0.000027582262,"about_ca_topic_score_gemma":0.000009414525,"teacher_disagreement_score":0.019763408,"about_ca_system_score_codex":0.000026196998,"about_ca_system_score_gemma":0.000030238889,"threshold_uncertainty_score":0.71428066},"labels":[],"label_agreement":null},{"id":"W2209344393","doi":"10.1089/zeb.2015.1158","title":"A Guide to Computational Tools and Design Strategies for Genome Editing Experiments in Zebrafish Using CRISPR/Cas9","year":2015,"lang":"en","type":"article","venue":"Zebrafish","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Fondation de la recherche en santé du Nouveau-Brunswick; Canadian Imperial Bank of Commerce","keywords":"CRISPR; Cas9; Genome editing; Biology; Computational biology; Genome; Genome engineering; Genetics; Gene","score_opus":0.05542883642669236,"score_gpt":0.3639308624834491,"score_spread":0.3085020260567567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2209344393","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44319555,0.00033322704,0.55559593,0.000071162714,0.00012985854,0.00035810363,0.000026945894,0.000013098589,0.00027613164],"genre_scores_gemma":[0.8903783,0.000002900506,0.1086598,0.0003739055,0.0003599719,0.000056626322,0.000075623015,0.000029255383,0.000063609856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990958,0.000025839578,0.00021850043,0.00029378847,0.000107754306,0.00025831236],"domain_scores_gemma":[0.9995948,0.000023093911,0.000035180296,0.00012213548,0.00009325028,0.00013150307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025499446,0.00013998865,0.00014103882,0.0000623926,0.000045049805,0.00010877032,0.0001030275,0.000080810016,0.00000339353],"category_scores_gemma":[0.00012305146,0.00015856346,0.000031304637,0.00007232695,0.000021339018,0.000014934553,0.00008838086,0.000042315027,0.0000013809232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000821696,0.00004244055,0.00030096975,0.000030327716,0.000034892393,0.0000057859675,0.0008103532,0.22784136,0.7645857,0.000121438716,0.005282906,0.00086166157],"study_design_scores_gemma":[0.009086286,0.0022923974,0.008806093,0.00019328318,0.00009677189,0.0002194756,0.01427756,0.09299794,0.7415086,0.0033445468,0.12472961,0.002447417],"about_ca_topic_score_codex":0.000027573225,"about_ca_topic_score_gemma":0.000017800488,"teacher_disagreement_score":0.44718274,"about_ca_system_score_codex":0.000028466411,"about_ca_system_score_gemma":0.00010470077,"threshold_uncertainty_score":0.64660305},"labels":[],"label_agreement":null},{"id":"W2213167196","doi":"10.1016/j.dib.2015.04.024","title":"Polymerase chain reaction-based gene removal from plasmids","year":2015,"lang":"en","type":"article","venue":"Data in Brief","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Illinois at Urbana-Champaign; Carnegie Institution for Science; McMaster University","keywords":"Restriction enzyme; Plasmid; Polymerase chain reaction; Multiplex polymerase chain reaction; Restriction digest; Cloning (programming); Multiplex; Restriction site; Gene; Molecular biology; Genetics; DNA; Biology; Computational biology; Computer science","score_opus":0.026246191949176413,"score_gpt":0.30847593099579756,"score_spread":0.28222973904662113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2213167196","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858469,0.0014283767,0.0106313545,0.00022170137,0.0003488069,0.00008860067,0.00092776667,0.000019369194,0.00048714696],"genre_scores_gemma":[0.98297995,0.000041118044,0.005788669,0.00038178416,0.00044412905,0.000006846004,0.010198322,0.000022346581,0.00013681034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992335,0.000022717513,0.00013895112,0.00034139038,0.00010561988,0.00015783244],"domain_scores_gemma":[0.99901056,0.00001154566,0.00002460094,0.00083910726,0.000018445833,0.000095760624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016533448,0.00010006788,0.00009004346,0.000032857886,0.000015566135,0.000015095383,0.0002883752,0.00009144905,0.000011603906],"category_scores_gemma":[0.00013996987,0.000109448585,0.0000180491,0.00006762956,0.00002428632,0.0000040768427,0.00014500962,0.00006886744,0.00001208068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011413763,0.00006865846,0.0023703333,0.0000053958497,0.000022601593,0.000048444967,0.000027108636,0.0008461916,0.9785266,0.000009629007,0.012812257,0.0051486203],"study_design_scores_gemma":[0.0015767874,0.000080170095,0.004394819,0.000013884478,0.000013645786,0.000021404363,0.000049280323,0.0084743695,0.67609525,0.000023370032,0.3089704,0.00028664235],"about_ca_topic_score_codex":0.0009366962,"about_ca_topic_score_gemma":0.0002717168,"teacher_disagreement_score":0.3024314,"about_ca_system_score_codex":0.0000128700085,"about_ca_system_score_gemma":0.00008478518,"threshold_uncertainty_score":0.4463184},"labels":[],"label_agreement":null},{"id":"W2214499393","doi":"10.1038/mt.2015.223","title":"Multidimensional Genome-wide Analyses Show Accurate FVIII Integration by ZFN in Primary Human Cells","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Genome; Biology; Computational biology; Human genome; Genetics; Virology; Computer science; Gene","score_opus":0.02562335696667484,"score_gpt":0.3334349340058113,"score_spread":0.3078115770391365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2214499393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94394237,0.0050874064,0.050217014,0.000080916354,0.00007768722,0.0001964096,0.000009745877,0.00001558541,0.0003728831],"genre_scores_gemma":[0.9964825,0.00026779986,0.0016567906,0.00065130444,0.000050006587,0.000024812967,0.00052162586,0.000034073706,0.00031111145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898654,0.000070369766,0.00021703223,0.0003291676,0.0001696536,0.00022724464],"domain_scores_gemma":[0.9994702,0.000006740236,0.000047813333,0.0003056765,0.00006823801,0.00010134555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017295183,0.00019555203,0.00017033558,0.00007098756,0.000035076733,0.000023347144,0.00014901218,0.0001241574,0.000014707107],"category_scores_gemma":[0.000017926941,0.00018411051,0.00008526509,0.00011441038,0.000033247972,0.000004816592,0.00004931671,0.00010142268,0.000010094744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049255355,0.00007112864,0.00033208786,0.0000033152373,0.000038506743,0.000010160118,0.00007949634,0.0045864703,0.9929664,0.0000053246017,0.00078172504,0.0010761272],"study_design_scores_gemma":[0.0010427732,0.00018297526,0.0020997168,0.0000067853175,0.0000063213747,0.0000024304345,0.00004687386,0.00025949016,0.9792505,0.000028830042,0.016842963,0.00023032697],"about_ca_topic_score_codex":0.000040341874,"about_ca_topic_score_gemma":0.000019391,"teacher_disagreement_score":0.052540123,"about_ca_system_score_codex":0.000034481185,"about_ca_system_score_gemma":0.000045700104,"threshold_uncertainty_score":0.7507809},"labels":[],"label_agreement":null},{"id":"W2215305044","doi":"10.3389/fgene.2015.00362","title":"Advanced In vivo Use of CRISPR/Cas9 and Anti-sense DNA Inhibition for Gene Manipulation in the Brain","year":2016,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Gene; Sense (electronics); DNA; Cas9; In vivo; Biology; Computational biology; Genetics; Chemistry","score_opus":0.02410067055632902,"score_gpt":0.3250000539040117,"score_spread":0.3008993833476827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2215305044","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.025313819,0.9247955,0.048218377,0.000029488609,0.00030261534,0.0011938965,0.00013302671,0.0000031886452,0.000010065348],"genre_scores_gemma":[0.0054642665,0.9824355,0.011604381,0.000038665265,0.000102370155,0.00010848235,0.00015226708,0.000046619083,0.00004740255],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985841,0.00011456409,0.000555877,0.0003876056,0.00010137239,0.0002565159],"domain_scores_gemma":[0.99936527,0.00006208488,0.00015703472,0.0003537741,0.000032173,0.00002968856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029862789,0.00026588008,0.00057075993,0.00023509032,0.000017068414,0.00001629377,0.00011076037,0.00034495658,9.767381e-7],"category_scores_gemma":[0.0001178711,0.00021458497,0.00011805511,0.00017120314,0.000054631677,0.000004866377,0.000061402694,0.00011146766,1.6102692e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103447084,0.00014705012,0.002211197,0.006604683,0.00009366715,0.000026574682,0.00032781332,0.003080074,0.040175263,0.000033628592,0.005039631,0.942157],"study_design_scores_gemma":[0.0015124283,0.0002153127,0.00093085127,0.0029837622,0.000099813115,0.000036659545,0.0000965629,0.0006727912,0.021483267,0.00014153973,0.9711976,0.00062942115],"about_ca_topic_score_codex":0.0000052624605,"about_ca_topic_score_gemma":0.000057069057,"teacher_disagreement_score":0.966158,"about_ca_system_score_codex":0.000034746234,"about_ca_system_score_gemma":0.0000510848,"threshold_uncertainty_score":0.87505215},"labels":[],"label_agreement":null},{"id":"W2222045377","doi":"10.1385/0-89603-310-4:115","title":"Electrotransformation in Salmonella","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada","keywords":"Transformation (genetics); Plasmid; Salmonella; DNA; Cloning (programming); Bacteria; Molecular cloning; Microbiology; Biology; Exogenous DNA; Chemistry; Molecular biology; Biochemistry; Genetics; Gene; Complementary DNA; Computer science","score_opus":0.016471330941956998,"score_gpt":0.29286539018039004,"score_spread":0.276394059238433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2222045377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6754237,0.007109103,0.02673568,0.000006229318,0.00020046606,0.00037612216,0.0000025794993,0.000030822266,0.2901153],"genre_scores_gemma":[0.99853265,0.00014611693,0.00021654829,0.000031435153,0.000046557572,0.000022215298,0.0000081064545,0.000010596767,0.0009857758],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995696,0.000019377212,0.000102335835,0.00011596951,0.000046336794,0.00014638944],"domain_scores_gemma":[0.999817,0.000001841036,0.000011991475,0.0001340057,0.000010552306,0.000024608267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007284353,0.00006956983,0.000053280666,0.000024425017,0.000020147216,0.000010265412,0.0000552106,0.00005366364,0.0000048485504],"category_scores_gemma":[0.000007566004,0.000074270334,0.000026032101,0.0000072546213,0.000011121015,9.1778526e-7,0.000007783244,0.00004787524,0.000001559424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044131728,0.000047822454,0.00014736982,0.000079439815,0.00003934031,0.0000062652502,0.00059500005,0.0029038112,0.9525046,0.017876241,0.0012050556,0.024550918],"study_design_scores_gemma":[0.0003273368,0.000048990158,0.0003041479,0.0000057174684,0.0000039015727,0.000005895929,0.000012878821,0.00008461636,0.81710595,0.00010132055,0.18188266,0.000116560266],"about_ca_topic_score_codex":0.000016604497,"about_ca_topic_score_gemma":0.000049767074,"teacher_disagreement_score":0.32310894,"about_ca_system_score_codex":0.0000049810333,"about_ca_system_score_gemma":0.000009341347,"threshold_uncertainty_score":0.30286562},"labels":[],"label_agreement":null},{"id":"W2223567094","doi":"10.1002/0471142905.hg2104s88","title":"Efficient CRISPR/Cas9‐Based Genome Engineering in Human Pluripotent Stem Cells","year":2016,"lang":"en","type":"article","venue":"Current Protocols in Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute for Health and Care Research; Canadian Institutes of Health Research; National Institutes of Health; Broad Institute; National Heart, Lung, and Blood Institute; Gladstone Institutes","keywords":"CRISPR; Genome editing; Induced pluripotent stem cell; Transcription activator-like effector nuclease; Biology; Zinc finger nuclease; Genome engineering; Computational biology; Cas9; Genome; Embryonic stem cell; Genetics; Gene","score_opus":0.026300013985691068,"score_gpt":0.3414671436948586,"score_spread":0.3151671297091675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2223567094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9565771,0.00073559943,0.026200991,0.000017180584,0.00018269916,0.016172266,0.00002098582,0.000038842358,0.000054342516],"genre_scores_gemma":[0.9856283,0.000024522198,0.00045055652,0.000014244266,0.0002460324,0.013457454,0.000017734388,0.00007315194,0.000087996945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977225,0.000060815924,0.0006425452,0.0006692607,0.00026213794,0.0006427481],"domain_scores_gemma":[0.9989642,0.000015516265,0.00010374848,0.00069866085,0.0000645406,0.0001533654],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031627776,0.00037808096,0.00029322147,0.00024212623,0.000063501655,0.000040759674,0.00046128494,0.00018053243,0.00002946987],"category_scores_gemma":[0.000013060463,0.00034435312,0.00012325865,0.00017875466,0.00006427224,0.0000025649435,0.00021341078,0.00020354964,0.000009567415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018426857,0.00022059192,0.0028909822,0.00020519657,0.000007976964,0.0000071479326,0.000054325952,0.1288597,0.86530215,0.000043020238,0.000039442115,0.0023510677],"study_design_scores_gemma":[0.0034939353,0.0005108165,0.011749821,0.00053430075,0.0000105318295,0.000002808113,0.000014239244,0.0045108697,0.9559239,0.00001943477,0.022503559,0.00072575],"about_ca_topic_score_codex":0.0000027577478,"about_ca_topic_score_gemma":0.000018788807,"teacher_disagreement_score":0.12434883,"about_ca_system_score_codex":0.00012548266,"about_ca_system_score_gemma":0.00006230404,"threshold_uncertainty_score":0.9999009},"labels":[],"label_agreement":null},{"id":"W2231037673","doi":"10.1371/journal.ppat.1005282","title":"Phages Fight Back: Inactivation of the CRISPR-Cas Bacterial Immune System by Anti-CRISPR Proteins","year":2016,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Immune system; Bacterial protein; Biology; Microbiology; Bacteria; Chemistry; Virology; Genetics; Gene","score_opus":0.013584988542664827,"score_gpt":0.2864821631516701,"score_spread":0.27289717460900526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2231037673","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018784321,0.99201137,0.0022985288,0.000019287767,0.0006283753,0.001471525,0.0013142503,0.000024045801,0.00035417147],"genre_scores_gemma":[0.012123043,0.98525196,0.00019504175,0.000007101742,0.00074263144,0.00020446102,0.00057017006,0.00012613129,0.00077946036],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99809885,0.00018899588,0.0006629026,0.00049862557,0.00022286263,0.000327786],"domain_scores_gemma":[0.9984338,0.000026970696,0.00045266078,0.00090072345,0.00011888855,0.00006692548],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015707259,0.00045716047,0.0009287781,0.000060397997,0.000082331484,0.000027238628,0.0004894723,0.0004726878,0.000059165253],"category_scores_gemma":[0.000107055996,0.00028873212,0.00052583293,0.00014724626,0.000058558235,0.0000047899393,0.00024003442,0.00016848427,0.00003723684],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009465445,0.00008012847,0.0000060967313,0.008927894,0.0003052269,0.000002270278,0.000020281252,9.3559487e-7,0.9485195,0.000012788755,0.0010149997,0.041100383],"study_design_scores_gemma":[0.00018204437,0.000066313514,0.000014589935,0.004216183,0.00025131242,0.000018703582,0.000009397197,0.0000019057359,0.48158902,4.3561917e-7,0.5133729,0.00027722085],"about_ca_topic_score_codex":0.0000063239504,"about_ca_topic_score_gemma":0.0000013910558,"teacher_disagreement_score":0.5123579,"about_ca_system_score_codex":0.000061735576,"about_ca_system_score_gemma":0.00014324037,"threshold_uncertainty_score":0.9999565},"labels":[],"label_agreement":null},{"id":"W2253036634","doi":"","title":"Open Source Approaches in Biotechnology: Utopia Revisited","year":2006,"lang":"en","type":"article","venue":"Maine law review","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Inefficiency; Argument (complex analysis); Field (mathematics); Open source; Criticism; Open innovation; Management science; Business; Biotechnology; Economics; Computer science; Political science; Marketing; Law; Biology","score_opus":0.018379620787749785,"score_gpt":0.2947667808200521,"score_spread":0.2763871600323023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2253036634","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.073630296,0.7930563,0.03467832,0.010245277,0.00017027954,0.0038336534,0.00003293432,0.00017953395,0.08417337],"genre_scores_gemma":[0.93582815,0.04450046,0.0086312,0.0037682557,0.00036266661,0.00023015599,0.0005890472,0.000089074594,0.0060010133],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99919116,0.00003443289,0.00023870097,0.00029167495,0.00004965349,0.00019434861],"domain_scores_gemma":[0.99949527,0.0000039149236,0.00004136388,0.00042270517,0.000011511613,0.00002523582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002748349,0.0001301316,0.00024173401,0.000021642629,0.000027088588,0.000021920006,0.00037343783,0.00010881285,0.000027376036],"category_scores_gemma":[0.000027711036,0.000118291035,0.000057157347,0.00016794016,0.00003971152,0.0000022697573,0.00029931028,0.00008392791,0.000014736097],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006821462,0.00088132394,0.0040333336,0.010710108,0.00016571715,0.00006670866,0.000022517772,0.0015126099,0.27323908,0.46450147,0.063165896,0.18163301],"study_design_scores_gemma":[0.00023889933,0.000045956855,0.00031660072,0.0004691422,0.0000149794205,0.000019652063,0.0000017542402,0.00004765265,0.0206111,0.00014527646,0.97791994,0.00016907131],"about_ca_topic_score_codex":0.00014277556,"about_ca_topic_score_gemma":0.00015335869,"teacher_disagreement_score":0.91475403,"about_ca_system_score_codex":0.000008645219,"about_ca_system_score_gemma":0.000011016386,"threshold_uncertainty_score":0.48237684},"labels":[],"label_agreement":null},{"id":"W2254704131","doi":"10.1007/978-3-319-22551-7_8","title":"Genetic Engineering and Precision Editing of Triticale Genomes","year":2015,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Triticale; Biology; Genome; Computational biology; Computer science; Genetics; Gene","score_opus":0.010519577226116827,"score_gpt":0.2584034820241972,"score_spread":0.2478839047980804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2254704131","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.040530603,0.2208378,0.10402234,0.00010814325,0.0015679469,0.0013406287,0.00022986566,0.00013306446,0.6312296],"genre_scores_gemma":[0.49988642,0.009623133,0.05153822,0.00006764557,0.004055391,0.00002720424,0.0002548075,0.00039405664,0.43415314],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991964,0.0000028598854,0.00024945627,0.00027242053,0.00013255574,0.00014629033],"domain_scores_gemma":[0.9995077,0.000014432808,0.000046424513,0.0002394932,0.000087870074,0.00010406902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009295473,0.00020357984,0.00023174992,0.00006320795,0.000012098865,0.000008981847,0.00009256642,0.0002641055,0.000054503456],"category_scores_gemma":[0.000046991863,0.00020425902,0.00006869769,0.000009596188,0.00003551847,9.2907766e-7,0.00013908558,0.000092739385,0.0000032289963],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010563534,0.00006124783,0.00035623708,0.0014818853,0.0006780329,0.000039656414,0.00015979304,0.010039437,0.7984873,0.013459799,0.015917972,0.15921298],"study_design_scores_gemma":[0.00093610835,0.00065495714,0.00030275053,0.00032367517,0.0001697594,0.00011367032,0.000028494751,0.002230657,0.07432562,0.0012116653,0.91871655,0.0009861013],"about_ca_topic_score_codex":0.0000015927881,"about_ca_topic_score_gemma":0.0000023860969,"teacher_disagreement_score":0.9027986,"about_ca_system_score_codex":0.0000072811654,"about_ca_system_score_gemma":0.000026972259,"threshold_uncertainty_score":0.8329441},"labels":[],"label_agreement":null},{"id":"W2254893726","doi":"10.1055/s-0035-1568877","title":"Changing Paradigm of Hemophilia Management: Extended Half-Life Factor Concentrates and Gene Therapy","year":2016,"lang":"en","type":"review","venue":"Seminars in Thrombosis and Hemostasis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Life expectancy; Medicine; Clotting factor; Genetic enhancement; Factor IX; Intensive care medicine; Quality of life (healthcare); Haemophilia; Hemarthrosis; Pediatrics; Surgery; Internal medicine; Gene; Genetics","score_opus":0.036262232455244674,"score_gpt":0.35531885349723835,"score_spread":0.31905662104199367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2254893726","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009033079,0.9899535,0.00014228394,0.0000358762,0.00010003955,0.00046646263,0.00013798231,0.0000082562365,0.00012247307],"genre_scores_gemma":[0.010170917,0.9890028,0.0004630275,0.00003658604,0.00007834252,0.00004931549,0.0000778365,0.000051151474,0.00007002743],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99850374,0.000046625708,0.00043128146,0.00053383625,0.00011430829,0.0003701774],"domain_scores_gemma":[0.9993304,0.00003465256,0.00016083925,0.00034585464,0.000017459526,0.00011081244],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014868946,0.00040054548,0.00091676234,0.00015781683,0.000053167838,0.000024527966,0.00016554736,0.00027137957,0.000027669994],"category_scores_gemma":[0.000012508794,0.00031671245,0.0001587228,0.00015644994,0.00011963363,0.0000046506498,0.00017179613,0.000093090806,0.0000010277992],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009562674,0.00004239173,0.00009519728,0.003094621,0.00033734518,0.0000034625043,0.00013401457,4.615639e-7,0.001374877,0.00012212046,0.00010901252,0.99467695],"study_design_scores_gemma":[0.0011838337,0.0002869365,0.00046986286,0.011199127,0.0003008185,0.000031126518,0.0002526473,0.00000803127,0.024166182,0.00012825047,0.9609107,0.0010625047],"about_ca_topic_score_codex":0.000003586311,"about_ca_topic_score_gemma":0.0000016440747,"teacher_disagreement_score":0.99361444,"about_ca_system_score_codex":0.000016255839,"about_ca_system_score_gemma":0.000032170545,"threshold_uncertainty_score":0.9999285},"labels":[],"label_agreement":null},{"id":"W2257239918","doi":"10.1007/s12079-015-0301-y","title":"Come together, right now….","year":2015,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computer science; Computational biology; Genome; Biology; Genetics; Gene","score_opus":0.014895933144391096,"score_gpt":0.2947857767214899,"score_spread":0.27988984357709884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2257239918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96393925,0.014151829,0.01844688,0.0002200581,0.00007531218,0.00003311613,6.40279e-7,0.0000029759935,0.0031299263],"genre_scores_gemma":[0.9921439,0.0009527321,0.006494555,0.00009039128,0.000072721334,4.4118835e-7,0.0000039709594,0.000006871632,0.00023440592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995808,0.000050748422,0.00018475535,0.000043658387,0.00007928006,0.000060734194],"domain_scores_gemma":[0.9994984,0.000015486316,0.00010233123,0.0001688577,0.00013189008,0.00008302503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004044217,0.00005276547,0.00008242202,0.000030750256,0.000034516157,0.000019972518,0.00015348548,0.000044498185,0.000009122304],"category_scores_gemma":[0.000024675568,0.00004570142,0.000037006717,0.000029459978,0.0000222824,0.0000038124538,0.000051059313,0.00009304802,0.0000014852287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049899554,0.000044044387,0.0009264402,0.000012358053,0.000026220596,0.0000018557769,0.0003874226,0.0021131006,0.99363345,0.00005912425,0.0019222032,0.0008238686],"study_design_scores_gemma":[0.0011355071,0.00026250974,0.0002605715,0.000035351244,0.000027358676,0.00008607607,0.0005657888,0.0005888264,0.8534979,0.0004113186,0.14298369,0.00014507047],"about_ca_topic_score_codex":0.0000014491341,"about_ca_topic_score_gemma":0.0000023499217,"teacher_disagreement_score":0.14106148,"about_ca_system_score_codex":0.0000054976363,"about_ca_system_score_gemma":0.00002900832,"threshold_uncertainty_score":0.186365},"labels":[],"label_agreement":null},{"id":"W2257429911","doi":"10.1186/s13059-016-0885-4","title":"Erratum to: Dynamics of gene silencing during X inactivation using allele-specific RNA-seq","year":2016,"lang":"en","type":"erratum","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Medical Research Council","keywords":"Biology; Gene silencing; Human genetics; Genetics; RNA-Seq; Allele; Gene; Computational biology; Gene expression; Transcriptome","score_opus":0.011323457475673634,"score_gpt":0.28457536913012516,"score_spread":0.2732519116544515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2257429911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7980525,0.01725797,0.15735838,0.00018346451,0.019239828,0.0008764518,0.0008691039,0.00006970812,0.00609263],"genre_scores_gemma":[0.93729997,0.0077647655,0.007683015,0.00013353064,0.009614477,0.00007303922,0.0065663056,0.00035030235,0.030514603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793476,0.00006201295,0.00054437306,0.0007678806,0.00012256816,0.00056842575],"domain_scores_gemma":[0.998698,0.000011466575,0.00027829045,0.0007043054,0.00017696247,0.00013100677],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015796322,0.00043588364,0.0005317875,0.00026379016,0.0000912256,0.000013579273,0.00042964035,0.0009921581,0.000042163585],"category_scores_gemma":[0.000057533016,0.00041832362,0.00018232715,0.00016124255,0.00008562545,0.0000035145322,0.00028712564,0.00030134502,0.0000108110535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005792599,0.000018673069,0.000044884102,0.00009758624,0.00011668289,0.0000031963511,0.00005497522,0.0005812074,0.99183357,0.000025955382,0.0061956393,0.0009696906],"study_design_scores_gemma":[0.0009449595,0.0007385492,0.0024471956,0.00020147194,0.000083322586,0.00009059427,0.00015922383,0.00027972,0.71876144,0.00016430464,0.2745396,0.0015896448],"about_ca_topic_score_codex":0.000039535345,"about_ca_topic_score_gemma":0.000047413996,"teacher_disagreement_score":0.27307215,"about_ca_system_score_codex":0.00020687099,"about_ca_system_score_gemma":0.00017691382,"threshold_uncertainty_score":0.99982685},"labels":[],"label_agreement":null},{"id":"W2261838712","doi":"10.1038/mtna.2015.58","title":"Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Exon; Duchenne muscular dystrophy; Dystrophin; Biology; Exon skipping; CRISPR; Genome editing; Intron; Genetics; Myogenesis; Gene; Exon shuffling; Open reading frame; Molecular biology; Alternative splicing; Computational biology; Peptide sequence","score_opus":0.006653538760114278,"score_gpt":0.2759622461430878,"score_spread":0.2693087073829735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2261838712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85673434,0.00063028256,0.14205141,0.0001937165,0.000054682027,0.00031146346,0.0000071369677,0.0000047704902,0.00001218797],"genre_scores_gemma":[0.9908869,0.00002230036,0.008890789,0.00008663084,0.000047662063,0.000008768929,0.000001878466,0.000027886403,0.0000271376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990729,0.0001435604,0.000194897,0.00025370618,0.0001542414,0.0001806645],"domain_scores_gemma":[0.9994087,0.000010057741,0.00008089518,0.00042827695,0.00004146821,0.000030553787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022716045,0.00015026274,0.0001247934,0.000038520615,0.000064320855,0.000015173989,0.00019786347,0.00013209949,0.000005373684],"category_scores_gemma":[0.000045423425,0.00008127341,0.00006129608,0.00013043209,0.00007987185,0.0000021590047,0.000090364316,0.00009537715,1.9221709e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004869277,0.000011381107,0.00042613834,0.00000647323,0.000025048561,0.0000013640329,0.00014396729,0.007956761,0.9867394,0.0000685121,0.0000031288334,0.0045691375],"study_design_scores_gemma":[0.00056183175,0.00010836999,0.002817759,0.000044740198,0.000007845163,0.000015880954,0.000033657234,0.0024582602,0.9933674,0.00013389764,0.00033125264,0.00011911215],"about_ca_topic_score_codex":0.000020215815,"about_ca_topic_score_gemma":0.0000067079227,"teacher_disagreement_score":0.1341526,"about_ca_system_score_codex":0.00002187987,"about_ca_system_score_gemma":0.000032365682,"threshold_uncertainty_score":0.33142334},"labels":[],"label_agreement":null},{"id":"W2264806126","doi":"10.1016/j.celrep.2016.01.036","title":"Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus","year":2016,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Ottawa; Hospital for Sick Children; University of Guelph","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research","keywords":"Messenger RNA; Protein biosynthesis; Translation (biology); Translational efficiency; Reprogramming; Stimulus (psychology); Biology; Cell biology; Ribosome profiling; Translational regulation; P-bodies; Genetics; Cell; Gene; Psychology","score_opus":0.009091046965038513,"score_gpt":0.26139477031129693,"score_spread":0.2523037233462584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2264806126","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97229844,0.0011328502,0.024250519,0.000014518064,0.00015563713,0.00011783359,0.0000013347423,0.000013253293,0.0020155916],"genre_scores_gemma":[0.99893427,0.000055451248,0.00044220474,0.0000057473712,0.000055362118,0.000006592682,0.0000056635436,0.000010778779,0.00048390942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993588,0.000009213279,0.00021098627,0.00021376164,0.00009311368,0.00011416763],"domain_scores_gemma":[0.9995385,0.000010810885,0.0000812424,0.00030182741,0.00003480151,0.0000328584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015066129,0.00007271183,0.00008152658,0.000025290137,0.000017417102,0.0000037362531,0.00004057098,0.000059628528,0.0000055029736],"category_scores_gemma":[0.000041022005,0.000052830765,0.000055511173,0.000037776572,0.000022754497,0.0000010021939,0.000013259727,0.000017337448,0.0000025110448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010131096,0.000018007442,0.0009284595,0.000033284963,0.000005565148,0.000011418324,0.000036646456,0.0009909528,0.9811376,0.0000021382589,0.00007258298,0.016753245],"study_design_scores_gemma":[0.0001311618,0.00013354911,0.0007665017,0.00004761494,0.000008461356,0.000063926585,0.000025127902,0.000037279868,0.9921456,0.00000661333,0.0065517137,0.00008245146],"about_ca_topic_score_codex":0.0000032742023,"about_ca_topic_score_gemma":8.936495e-7,"teacher_disagreement_score":0.026635826,"about_ca_system_score_codex":0.00000624221,"about_ca_system_score_gemma":0.000020265114,"threshold_uncertainty_score":0.2154376},"labels":[],"label_agreement":null},{"id":"W2264932884","doi":"10.1038/srep09934","title":"Promoter-Autonomous Functioning in a Controlled Environment using Single Molecule FISH","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Promoter; Gene; Biology; Transcription (linguistics); ENCODE; Locus (genetics); Genetics; Transcription factor; Transcriptional regulation; Computational biology; Regulation of gene expression; Gene expression","score_opus":0.01571928031842138,"score_gpt":0.2553093678162854,"score_spread":0.239590087497864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2264932884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98257464,0.0003767373,0.014232368,0.000030590898,0.0015836862,0.0002946045,8.133979e-7,0.0000135439695,0.00089299754],"genre_scores_gemma":[0.99701566,0.0000015264748,0.0014573784,0.000022697805,0.00008192403,0.00002178473,0.00004386753,0.000015653202,0.0013395132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872744,0.00002707282,0.00031888197,0.00049153005,0.00019347334,0.00024158394],"domain_scores_gemma":[0.9993212,0.0000026326713,0.000098665616,0.00043194607,0.000039014983,0.00010648878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006630394,0.00011601859,0.00015035986,0.00007747138,0.000061357125,0.00009212064,0.000061859006,0.00006934146,0.000015729038],"category_scores_gemma":[0.00010293426,0.000115861876,0.000064708714,0.00009889483,0.000059398095,0.0000050700564,0.000081332466,0.00005196634,0.000003490445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003004558,0.00008941442,0.001498963,0.0000055078094,0.000013785796,0.000090365975,0.00011290848,0.030066367,0.96693325,9.539995e-7,0.00073048274,0.00042795835],"study_design_scores_gemma":[0.002068497,0.00022504384,0.0004536324,0.00003093175,0.00002975153,0.00043281948,0.0001989115,0.009921731,0.9319406,0.00020637883,0.054092374,0.0003993044],"about_ca_topic_score_codex":0.000016324368,"about_ca_topic_score_gemma":0.000020908368,"teacher_disagreement_score":0.053361893,"about_ca_system_score_codex":0.000057433033,"about_ca_system_score_gemma":0.000097823446,"threshold_uncertainty_score":0.47247103},"labels":[],"label_agreement":null},{"id":"W2271082097","doi":"10.1016/j.chembiol.2015.12.009","title":"Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases","year":2016,"lang":"en","type":"review","venue":"Cell chemical biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Defense Advanced Research Projects Agency; Howard Hughes Medical Institute","keywords":"Genome editing; Transcription activator-like effector nuclease; Computational biology; Computer science; CRISPR; Genome; Biology; Genetics; Gene","score_opus":0.06690512022250163,"score_gpt":0.3134690772928986,"score_spread":0.24656395707039697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2271082097","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015658456,0.98329335,0.013106949,0.0000440809,0.00021715299,0.00071118044,0.00014031547,0.00005877123,0.0008623225],"genre_scores_gemma":[0.02429288,0.9706721,0.002079471,0.00007642675,0.0016363937,0.00021529311,0.00080126425,0.00012675095,0.00009942354],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99733084,0.000074467396,0.000566824,0.0011558505,0.00006213124,0.0008098956],"domain_scores_gemma":[0.99888057,0.0000935883,0.00018287952,0.00045412494,0.000030933774,0.00035791026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018591649,0.0006322471,0.0012170321,0.00010889394,0.00006549667,0.000034759214,0.00044992365,0.0011028934,0.000030925952],"category_scores_gemma":[0.00013910652,0.0004986769,0.0003362851,0.000112040674,0.00030561676,0.0000026445016,0.00057127443,0.00029535484,0.00003234649],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068066955,0.000117344716,0.000026823725,0.0037123626,0.0004256232,0.000007036889,0.00003361919,0.0000029332516,0.65878767,0.0011643477,0.00035916897,0.335295],"study_design_scores_gemma":[0.0004782841,0.00018812867,1.2157506e-7,0.00041187095,0.00018397889,0.000049260034,0.000015331787,0.000008199013,0.031163756,0.00019140086,0.96663624,0.0006734506],"about_ca_topic_score_codex":0.000005016821,"about_ca_topic_score_gemma":9.497262e-7,"teacher_disagreement_score":0.96627706,"about_ca_system_score_codex":0.00009488117,"about_ca_system_score_gemma":0.00007773042,"threshold_uncertainty_score":0.9997465},"labels":[],"label_agreement":null},{"id":"W2271163371","doi":"10.1073/pnas.1517883113","title":"Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM","year":2016,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":252,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Defense Threat Reduction Agency; National Cancer Institute; Croucher Foundation; National Institutes of Health; Office of Naval Research","keywords":"CRISPR; Computational biology; Multiplex; Cas9; Biology; Trans-activating crRNA; Gene; Genetics; Computer science","score_opus":0.02277222497696365,"score_gpt":0.31688998255935147,"score_spread":0.29411775758238784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2271163371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99549246,0.00036372244,0.00033285702,0.0017795843,0.000020327641,0.00012988875,0.000026625945,0.000007967857,0.0018465681],"genre_scores_gemma":[0.9965314,0.000052849427,0.002761258,0.00012656851,0.00005898309,0.0000062042986,2.7213406e-7,0.0000048165625,0.0004576005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990338,0.0000036518409,0.00019267661,0.00020510584,0.00041992837,0.00014482682],"domain_scores_gemma":[0.9996478,0.000030501615,0.00013578398,0.000009495547,0.00014359146,0.000032834767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052028697,0.00007964181,0.00009066292,0.000046435875,0.000091127935,0.0000097621,0.0004804411,0.00007429669,0.000009044499],"category_scores_gemma":[0.00038577415,0.00004712071,0.00006097364,0.00017863678,0.00030762475,0.000014200424,0.00013572218,0.000047405974,5.9521864e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011668367,0.0000127082085,0.0024768137,0.000012840289,0.000011207597,1.0520099e-9,0.000015152603,0.000049940158,0.9930746,0.0007102944,0.0029025597,0.00072223856],"study_design_scores_gemma":[0.00028946757,0.000040129187,0.008087807,0.00004176612,0.0000048319366,0.0000026150224,0.000041280335,0.00021000543,0.98821265,0.0009122769,0.0020831837,0.00007396836],"about_ca_topic_score_codex":0.0000025066913,"about_ca_topic_score_gemma":4.5618965e-8,"teacher_disagreement_score":0.0056109936,"about_ca_system_score_codex":0.000006031589,"about_ca_system_score_gemma":0.000012305054,"threshold_uncertainty_score":0.19215268},"labels":[],"label_agreement":null},{"id":"W2272470775","doi":"10.1016/j.molmed.2016.01.007","title":"Exon Snipping in Duchenne Muscular Dystrophy","year":2016,"lang":"en","type":"letter","venue":"Trends in Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Duchenne muscular dystrophy; Dystrophin; Exon; CRISPR; Exon skipping; Muscular dystrophy; Limiting; Genome editing; Gene; Genetics; Medicine; Bioinformatics; Biology; Alternative splicing","score_opus":0.009542288190661549,"score_gpt":0.3012511888492293,"score_spread":0.29170890065856775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2272470775","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13161616,0.037042163,0.046694998,0.7643706,0.003486705,0.001031969,0.000103931445,0.00014336927,0.015510094],"genre_scores_gemma":[0.55069464,0.0032203123,0.0035379746,0.40165713,0.022476008,0.00042396912,0.0051425085,0.00083539553,0.012012051],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99726367,0.00012470706,0.0005886646,0.00088044046,0.00038678554,0.00075571926],"domain_scores_gemma":[0.9988245,0.000020391084,0.000115390445,0.0009067898,0.000047038728,0.00008589769],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032696364,0.0005402984,0.0006292654,0.0007716929,0.000020423247,0.000010080338,0.00044257642,0.00092607015,0.00017353489],"category_scores_gemma":[0.00011492215,0.00045355217,0.00017597654,0.0004046101,0.00014438202,0.0000028169031,0.0001455922,0.0009068787,0.0000104446],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037523394,0.000027173806,0.00019517564,0.00018474969,0.00011607311,0.0032735544,0.000091018475,0.0002674619,0.77551734,0.000014182332,0.1920429,0.028232837],"study_design_scores_gemma":[0.0026014475,0.00034336981,0.0009209188,0.00080895243,0.00006460742,0.000084437044,0.000021393871,0.00005140493,0.03038253,0.00006848168,0.9638978,0.00075462746],"about_ca_topic_score_codex":0.00009040073,"about_ca_topic_score_gemma":0.000047462443,"teacher_disagreement_score":0.77185494,"about_ca_system_score_codex":0.00007289824,"about_ca_system_score_gemma":0.000039321272,"threshold_uncertainty_score":0.9997916},"labels":[],"label_agreement":null},{"id":"W2273649647","doi":"10.1126/science.aad6778","title":"Editing policy to fit the genome?","year":2016,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre; McGill Genome Centre","funders":"Canada Research Chairs","keywords":"Genome; Computational biology; Genome editing; Biology; Computer science; Genetics; Gene","score_opus":0.008400296248479405,"score_gpt":0.3200319843865446,"score_spread":0.3116316881380652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2273649647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94497085,0.00020069165,0.04420896,0.006923059,0.0002824341,0.000102024365,0.000006035957,0.000012478717,0.0032934772],"genre_scores_gemma":[0.99751294,0.000013574595,0.00055340526,0.0005190653,0.0005644843,0.0000049513383,2.0237698e-7,0.000003508922,0.00082786096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99950606,0.0000034985396,0.00004582618,0.00015845714,0.000095239375,0.00019089939],"domain_scores_gemma":[0.9996737,0.0000046864325,0.000008625055,0.00021807433,0.00003140244,0.00006348524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019991834,0.00003995997,0.000023411387,0.000028603941,0.000096654265,0.000018504552,0.00029213566,0.000013207176,0.000008671316],"category_scores_gemma":[0.00023185283,0.000021390182,0.000014895129,0.00018098744,0.000108216,0.0000017480127,0.00013743137,0.000013634094,0.000032839773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[7.224091e-7,9.969837e-7,0.00012532723,5.037024e-7,6.632187e-7,1.2326457e-7,0.000033151333,0.00008788741,0.98948175,0.00007383672,0.00022805222,0.009966989],"study_design_scores_gemma":[0.00006320943,0.000049906892,0.018060803,0.0000052418413,9.54376e-7,0.000006856663,0.00004093385,0.000012714887,0.77938986,0.00007987086,0.20221241,0.000077245444],"about_ca_topic_score_codex":0.0000037765944,"about_ca_topic_score_gemma":0.0000059680165,"teacher_disagreement_score":0.2100919,"about_ca_system_score_codex":0.000009726783,"about_ca_system_score_gemma":0.0000639281,"threshold_uncertainty_score":0.08722663},"labels":[],"label_agreement":null},{"id":"W2274502064","doi":"10.1016/b978-0-12-801185-0.00010-6","title":"Adapting CRISPR/Cas9 for Functional Genomics Screens","year":2014,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Cas9; Genome editing; Computational biology; Biology; Functional genomics; Guide RNA; Genome; Genomics; Subgenomic mRNA; Genetics; Gene","score_opus":0.04653007453263237,"score_gpt":0.4289506058911761,"score_spread":0.38242053135854376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2274502064","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14514226,0.0010336627,0.8490366,0.00032267364,0.0020672325,0.0005846728,0.000021970018,0.00005400095,0.0017369611],"genre_scores_gemma":[0.1277058,0.000116352094,0.8688319,0.0014364987,0.000839176,0.00035191228,0.00010067999,0.0001303709,0.00048733086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.992107,0.0037947583,0.0011469912,0.001511654,0.00015452555,0.001285107],"domain_scores_gemma":[0.9954839,0.0028614698,0.0002773419,0.0010415189,0.00014362596,0.00019217776],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008803017,0.00064753066,0.0010502469,0.0006328238,0.00016032964,0.00002417022,0.0006495235,0.0012732553,0.0000823746],"category_scores_gemma":[0.0052728695,0.0007100765,0.00031805606,0.00039757555,0.0003785139,0.000009877513,0.00036678335,0.00086156215,0.000011955488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065915345,0.0002537433,0.003025239,0.00007082187,0.000112480215,0.000019323948,0.0001781677,0.0193147,0.87405986,0.0066337246,0.0010054624,0.09466735],"study_design_scores_gemma":[0.0085093705,0.0048288153,0.12688334,0.00010191661,0.00016565922,0.0008324265,0.000568845,0.011764976,0.53887343,0.027286163,0.27754784,0.0026371991],"about_ca_topic_score_codex":0.00007877757,"about_ca_topic_score_gemma":0.0005322401,"teacher_disagreement_score":0.3351864,"about_ca_system_score_codex":0.00014180956,"about_ca_system_score_gemma":0.00013178971,"threshold_uncertainty_score":0.999535},"labels":[],"label_agreement":null},{"id":"W2280557044","doi":"10.1016/j.gendis.2016.02.001","title":"Gene editing: A new step and a new direction toward finding a cure for Duchenne muscular dystrophy (DMD)","year":2016,"lang":"en","type":"article","venue":"Genes & Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Cystic Fibrosis Canada; Canadian Institutes of Health Research; Hospital for Sick Children; National Institute of Neurological Disorders and Stroke; Cystic Fibrosis Foundation Therapeutics","keywords":"Duchenne muscular dystrophy; Dystrophin; Exon; Muscular dystrophy; Exon skipping; Gene; Muscle disease; Disease; Neuromuscular disease; Medicine; Genome editing; Bioinformatics; Genetic enhancement; Genetics; Biology; Internal medicine; Alternative splicing; CRISPR","score_opus":0.013347313386996473,"score_gpt":0.2782902035300337,"score_spread":0.26494289014303724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2280557044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.738268,0.025343953,0.23468734,0.00069857365,0.00046546277,0.00034363903,0.00012327782,0.00005238648,0.000017340248],"genre_scores_gemma":[0.98742545,0.0015635067,0.0061607338,0.00007726756,0.0032087883,0.000055853205,0.00009236554,0.000047601032,0.0013684592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990986,0.000012898572,0.00014279362,0.00038314407,0.00008799989,0.00027454863],"domain_scores_gemma":[0.9994136,0.000015801921,0.000044293196,0.0002129852,0.00004176114,0.0002715681],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037022462,0.00017994284,0.00014332215,0.00004204016,0.0000697008,0.000033837485,0.00009124174,0.000086904416,0.000016344946],"category_scores_gemma":[0.00009234336,0.00014506475,0.00012829615,0.00005261861,0.000024845242,0.0000064234823,0.00007001705,0.000021802194,0.0000024465653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009875109,0.000025806357,0.002479164,0.00006200471,0.00009677058,0.0000029212122,0.00003537169,0.00007873639,0.8019662,0.000016836495,0.008830352,0.1863071],"study_design_scores_gemma":[0.0029638398,0.00052021333,0.014856685,0.00010264724,0.0003137881,0.000036393638,0.00010476085,0.00015000801,0.59054345,0.0002652708,0.38951156,0.0006313709],"about_ca_topic_score_codex":0.000034482626,"about_ca_topic_score_gemma":0.0000136966455,"teacher_disagreement_score":0.38068122,"about_ca_system_score_codex":0.000012560442,"about_ca_system_score_gemma":0.00008394795,"threshold_uncertainty_score":0.5915569},"labels":[],"label_agreement":null},{"id":"W2281751680","doi":"","title":"Strategies for Patenting in Biotechnology","year":2009,"lang":"en","type":"article","venue":"Current Trends in Biotechnology and Pharmacy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Intellectual property; Surprise; Profit (economics); Business; Scientific discovery; Biotechnology; Political science; Engineering ethics; Engineering; Law; Economics; Sociology; Biology","score_opus":0.028496930026341058,"score_gpt":0.38435025591490773,"score_spread":0.35585332588856666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2281751680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.973375,0.01376271,0.009752245,0.002367961,0.00030739306,0.00016514314,0.0000149148555,0.00007238672,0.00018220133],"genre_scores_gemma":[0.99572784,0.0033379425,0.00070536975,0.000051375846,0.000059909653,0.000027707332,0.000059931244,0.000009655098,0.000020300655],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990021,0.000014304174,0.00022663471,0.00037964605,0.00003307723,0.00034424587],"domain_scores_gemma":[0.99973327,0.00000820784,0.00003903917,0.00017952573,0.00001075307,0.000029229053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012768261,0.0001686526,0.00016804357,0.00042801505,0.000038635626,0.000012893206,0.00017042481,0.0002724773,0.000006438524],"category_scores_gemma":[0.0000210416,0.00017509416,0.000044228014,0.0002918458,0.00009406967,0.0000060819702,0.00006288702,0.00026721696,7.1717767e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054627748,0.00009175057,0.0022079456,0.000022108516,0.000008295022,0.0000034522275,0.000035636618,0.00010691644,0.35229966,0.0037284712,0.0002602124,0.64118093],"study_design_scores_gemma":[0.0039382423,0.00042919596,0.008911635,0.000068271234,0.000021528209,0.000043309374,0.0002530794,0.0031841928,0.8281434,0.0036197475,0.15081142,0.00057597616],"about_ca_topic_score_codex":0.000006056392,"about_ca_topic_score_gemma":0.000042115913,"teacher_disagreement_score":0.6406049,"about_ca_system_score_codex":0.000009319579,"about_ca_system_score_gemma":0.00001710323,"threshold_uncertainty_score":0.7140133},"labels":[],"label_agreement":null},{"id":"W2284413061","doi":"10.1038/srep19675","title":"Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":204,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Core Research for Evolutional Science and Technology; Japan Science and Technology Agency; National Center of Neurology and Psychiatry; Japan Society for the Promotion of Science; Japan Science Society; Takeda Pharmaceutical Company","keywords":"CRISPR; Cas9; Guide RNA; Endonuclease; Computational biology; Genome editing; Cleavage (geology); Biology; DNA; Subgenomic mRNA; Context (archaeology); Genetics; Gene","score_opus":0.006915400733105888,"score_gpt":0.25888202782161646,"score_spread":0.2519666270885106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2284413061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98676306,0.0004423502,0.009986344,0.00011821009,0.0010754324,0.00018485304,0.0000075296416,0.000025335083,0.0013968732],"genre_scores_gemma":[0.9970712,0.000003558102,0.000067633744,0.000008814692,0.000039103717,0.000008944014,0.000012120969,0.000011205952,0.0027774358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891126,0.000031276777,0.00019497516,0.0003886479,0.00026552076,0.00020829048],"domain_scores_gemma":[0.99898034,0.00001739591,0.00016002147,0.0006610008,0.00013353418,0.00004769838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070092577,0.00010202083,0.00010419841,0.000032713244,0.0001249827,0.000036794492,0.0001569523,0.0000622452,0.000004546023],"category_scores_gemma":[0.00014971981,0.000050523096,0.000056979978,0.00017944638,0.0002506028,0.000003098485,0.00005847516,0.000037649785,0.0000017902253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006646723,0.00001540289,0.0011124882,0.000015070399,0.000021068372,0.000035101926,0.00005661177,0.000101158286,0.9906731,0.000031630152,0.0073847934,0.0005468764],"study_design_scores_gemma":[0.000103356666,0.00007307475,0.0027828002,0.00008492515,0.000017334261,0.00016425457,0.00011796877,0.000013471256,0.99085677,0.000015594991,0.0056630643,0.00010741479],"about_ca_topic_score_codex":0.000007349643,"about_ca_topic_score_gemma":0.000027309612,"teacher_disagreement_score":0.010308111,"about_ca_system_score_codex":0.000016753309,"about_ca_system_score_gemma":0.00007553997,"threshold_uncertainty_score":0.2060272},"labels":[],"label_agreement":null},{"id":"W2289992440","doi":"10.1371/journal.pone.0150188","title":"Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research; Québec Consortium for Drug Discovery; Weston Brain Institute; ALS Association; Fondation Brain Canada; ALS Society of Canada","keywords":"CRISPR; Genome editing; Zebrafish; Biology; Genetics; Computational biology; Gene; Cas9; Palindrome; Genome; Homology (biology); Homology directed repair; DNA repair; Nucleotide excision repair","score_opus":0.022001646963651554,"score_gpt":0.26733237404996535,"score_spread":0.2453307270863138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2289992440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960398,0.0018255142,0.0014613078,0.00034030582,0.00002485991,0.0002051122,0.000015208453,0.000006926246,0.000080937934],"genre_scores_gemma":[0.9990762,0.00013982055,0.0006376579,0.000035506775,0.000049245064,0.000026816258,0.0000054386287,0.000009771405,0.000019530074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993566,0.00010020604,0.00018245363,0.00014750888,0.000074505595,0.00013869283],"domain_scores_gemma":[0.9996307,0.000060202005,0.000041184627,0.00021241119,0.000038503014,0.000017007249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020262586,0.000079067635,0.00013361624,0.00004562762,0.000027736176,0.0000068545473,0.00011100587,0.000066072265,0.0000034768516],"category_scores_gemma":[0.00008354106,0.000045743345,0.000023319182,0.00009337995,0.00006106312,0.0000022015865,0.00004796657,0.000044071454,6.1500236e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012783236,0.00008631329,0.0061466373,0.000050495983,0.00004139763,0.000004755406,0.00025331994,0.00009914031,0.9928548,0.000046280496,0.000013422864,0.00039065036],"study_design_scores_gemma":[0.0006323879,0.00010123839,0.02933156,0.00016138075,0.000059188926,0.000041333366,0.0007928858,0.0010666918,0.967543,0.00005139112,0.000087544395,0.00013140567],"about_ca_topic_score_codex":0.00009648749,"about_ca_topic_score_gemma":0.0002369692,"teacher_disagreement_score":0.02531181,"about_ca_system_score_codex":0.000010412923,"about_ca_system_score_gemma":0.000018316721,"threshold_uncertainty_score":0.18653595},"labels":[],"label_agreement":null},{"id":"W2295326929","doi":"10.1016/j.stem.2016.01.022","title":"CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs","year":2016,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":549,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Biomedical Imaging and Bioengineering; Howard Hughes Medical Institute; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Canadian Institutes of Health Research; Innovative Genomics Institute; University of California, San Francisco; Center for AIDS Research, University of Washington; National Heart, Lung, and Blood Institute; Gladstone Institutes; National Institute on Drug Abuse","keywords":"Biology; CRISPR; CRISPR interference; Induced pluripotent stem cell; Gene silencing; Cas9; Genome editing; RNA interference; Psychological repression; Regulation of gene expression; Gene expression; Gene; Cell biology; Gene knockdown; Genetics; Computational biology; Transcription activator-like effector nuclease; Embryonic stem cell; RNA","score_opus":0.011437423085089767,"score_gpt":0.24750926896723635,"score_spread":0.23607184588214658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2295326929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988213,0.0032228243,0.0059892028,0.000017912978,0.00015017252,0.00010309261,0.0000051625075,0.000010153041,0.0022884887],"genre_scores_gemma":[0.99702287,0.0005971178,0.00023468562,0.00001914005,0.000083885025,0.0000052931136,0.0000067454516,0.000017881823,0.0020123739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912333,0.000024074448,0.00017995143,0.0003591657,0.00006957753,0.00024387403],"domain_scores_gemma":[0.9995965,0.000014018997,0.00004139238,0.00025127066,0.000023041915,0.000073798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012056365,0.00014322599,0.000120445744,0.000060838545,0.000045482117,0.000020715488,0.00015202064,0.00010314176,0.00002096541],"category_scores_gemma":[0.000002269863,0.000118595395,0.000033860633,0.000067918256,0.00003858178,0.0000037212994,0.00013046009,0.00006549094,0.000016895163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008561871,0.000028997925,0.0008985604,0.000036580946,0.0000023831794,0.0000044987496,0.00014677356,0.00006207445,0.9969682,0.0000050702038,0.00038351564,0.0014547715],"study_design_scores_gemma":[0.0004926487,0.00013005617,0.0010541257,0.00004244233,0.0000042078836,0.0000034324323,0.00021878471,0.000012691172,0.9949628,0.00000814618,0.0028891498,0.00018153245],"about_ca_topic_score_codex":0.000008898767,"about_ca_topic_score_gemma":0.000010796531,"teacher_disagreement_score":0.008809887,"about_ca_system_score_codex":0.00001902291,"about_ca_system_score_gemma":0.00001830178,"threshold_uncertainty_score":0.483618},"labels":[],"label_agreement":null},{"id":"W2300360330","doi":"10.1038/ncomms10770","title":"Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Partenariat Canadien Contre Le Cancer; Deutschen Konsortium für Translationale Krebsforschung; Helmholtz-Gemeinschaft","keywords":"CRISPR; Pancreatic cancer; Biology; Genome editing; Cas9; Computational biology; Genome engineering; Context (archaeology); Genetics; Gene; Cancer","score_opus":0.007032272479904737,"score_gpt":0.2785222959415714,"score_spread":0.2714900234616667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2300360330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95896924,0.032799304,0.0065953545,0.0012246749,0.000097838274,0.000192937,0.000053303476,0.00002618164,0.000041142554],"genre_scores_gemma":[0.9927566,0.005007963,0.0019001985,0.000084083214,0.000040574472,0.000083440806,0.00006767411,0.000016959886,0.000042479223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995144,0.000029853643,0.000121282465,0.00016427525,0.00004667314,0.00012349978],"domain_scores_gemma":[0.9994551,0.000051029423,0.000020104048,0.00038832152,0.000044053555,0.000041371728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007621902,0.00010012934,0.00008291195,0.00006016858,0.000054158787,0.000009358002,0.00017848378,0.00019836552,0.0000048610527],"category_scores_gemma":[0.000057444322,0.0000889759,0.000029028974,0.00010336556,0.000033818473,0.0000051670095,0.000040371826,0.00018742896,7.965028e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009959714,0.000023989705,0.0022793298,0.000010649703,0.000016688387,1.0481217e-7,0.000031279953,0.000615257,0.994548,0.000012083253,0.00013008193,0.002322532],"study_design_scores_gemma":[0.0019204097,0.00009584552,0.06803132,0.0001277261,0.00006259614,0.000009901288,0.00006731714,0.0044418005,0.8098956,0.0000072766184,0.11481331,0.0005269343],"about_ca_topic_score_codex":0.00007558839,"about_ca_topic_score_gemma":0.00052046456,"teacher_disagreement_score":0.18465249,"about_ca_system_score_codex":0.000031622807,"about_ca_system_score_gemma":0.000025796635,"threshold_uncertainty_score":0.3628332},"labels":[],"label_agreement":null},{"id":"W2300745597","doi":"10.1016/bs.mie.2016.01.017","title":"Preparation and Analysis of Native Chromatin-Modifying Complexes","year":2016,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Chromatin; Effector; Biology; Histone; Nucleosome; CRISPR; Computational biology; Epigenetics; Genetics; Cell biology; DNA; Gene","score_opus":0.035528664389470895,"score_gpt":0.46113654002874627,"score_spread":0.4256078756392754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2300745597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59142244,0.0009664797,0.40641692,0.00009442378,0.00025439734,0.00023232716,0.000021610525,0.000016663487,0.0005747315],"genre_scores_gemma":[0.51028544,0.0002030296,0.48913476,0.00011292083,0.000045355126,0.00007086737,0.000022461307,0.000025320865,0.00009985556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9937163,0.0036877266,0.00094493583,0.000960999,0.00012731174,0.0005627382],"domain_scores_gemma":[0.9966642,0.0021603107,0.00030745316,0.0006782797,0.0000979587,0.00009176243],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004079655,0.0003867051,0.0010803419,0.0010766014,0.00005614162,0.00000852536,0.00034610517,0.0006309409,0.00008036002],"category_scores_gemma":[0.0025329248,0.0003313638,0.00018303051,0.00082041975,0.00053363916,0.000010855328,0.00026552536,0.00028012894,0.0000016117557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024866773,0.00013557286,0.013405411,0.000034709232,0.00037211107,0.000011859539,0.0005222659,0.0017954122,0.94206536,0.0016586746,0.00003814232,0.03971179],"study_design_scores_gemma":[0.0018356683,0.0012601195,0.36508727,0.000063952255,0.00023494672,0.00007185017,0.00018252617,0.0012577967,0.6230814,0.0048712534,0.0014919352,0.0005613031],"about_ca_topic_score_codex":0.000093050905,"about_ca_topic_score_gemma":0.0006735046,"teacher_disagreement_score":0.35168186,"about_ca_system_score_codex":0.000070356444,"about_ca_system_score_gemma":0.000055659508,"threshold_uncertainty_score":0.9999138},"labels":[],"label_agreement":null},{"id":"W2304491401","doi":"10.1093/hmg/ddw094","title":"Combined genetic and splicing analysis of BRCA1 c.[594-2A&gt;C; 641A&gt;G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms","year":2016,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Cancer Institute; Instituto de Salud Carlos III; Cancer Council Victoria; Unicancer; Canadian Institutes of Health Research; NorthShore University HealthSystem; Associazione Italiana per la Ricerca sul Cancro; Bundesministerium für Bildung und Forschung; Deutsches Krebsforschungszentrum; Universiteit Leiden; National Health and Medical Research Council; Cancer Research UK; Breast Cancer Research Foundation; Institut National de la Santé et de la Recherche Médicale; National Institutes of Health; Ovarian Cancer Research Fund; McGill University","keywords":"Biology; Exon skipping; RNA splicing; Exon; Genetics; Alternative splicing; Gene; Allele; Molecular biology; RNA","score_opus":0.012857948075442487,"score_gpt":0.28360140686512836,"score_spread":0.27074345878968586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2304491401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7174903,0.0034149988,0.27849326,0.00012284797,0.00006287854,0.00035751,0.000042555497,0.0000071007885,0.000008573089],"genre_scores_gemma":[0.9848789,0.0008334571,0.013979175,0.00008164868,0.000045606805,0.000048693517,0.00006797243,0.000039951232,0.000024626544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829406,0.000065497916,0.0005860946,0.0005143381,0.00022496363,0.00031504934],"domain_scores_gemma":[0.99884945,0.000050914532,0.000196318,0.0006218774,0.00018938632,0.000092050235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022143136,0.00025421905,0.00035349812,0.00019739139,0.00008157824,0.000019343814,0.00032458353,0.0001392003,0.0000019674899],"category_scores_gemma":[0.000083573635,0.00019826162,0.00018784044,0.00031487527,0.00013790134,0.0000049393434,0.00008640823,0.00006582598,1.9811806e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005660444,0.00003684207,0.0020553805,0.00008978454,0.00031627106,0.000005332521,0.00012045235,0.0029014985,0.99144554,0.0011286017,0.0000061773444,0.0018374859],"study_design_scores_gemma":[0.0013886958,0.00021476515,0.3650058,0.00012777267,0.00069449906,0.00000469681,0.000030385472,0.011431097,0.6194685,0.00047834642,0.00072694174,0.0004284682],"about_ca_topic_score_codex":0.000009914082,"about_ca_topic_score_gemma":0.000052728246,"teacher_disagreement_score":0.37197703,"about_ca_system_score_codex":0.000027179094,"about_ca_system_score_gemma":0.00007140315,"threshold_uncertainty_score":0.8084874},"labels":[],"label_agreement":null},{"id":"W2305811183","doi":"10.1002/mbo3.348","title":"<scp>CRISPR</scp>1 analysis of naturalized surface water and fecal <i>Escherichia coli</i> suggests common origin","year":2016,"lang":"en","type":"article","venue":"MicrobiologyOpen","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Ministry of Agriculture and Forestry","funders":"Alberta Agriculture and Forestry","keywords":"CRISPR; Biology; Allele; Genetics; Escherichia coli; Gene","score_opus":0.006431874370944754,"score_gpt":0.27260126555616937,"score_spread":0.2661693911852246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2305811183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99714357,0.0011636693,0.0009477677,0.0001240243,0.000110854846,0.00017073563,0.00010584834,0.000013446771,0.00022008225],"genre_scores_gemma":[0.9968812,0.00029140027,0.000660988,0.00017622253,0.0000330848,0.0000060307652,0.00027846856,0.00001917969,0.0016534445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989063,0.00008800396,0.00025916524,0.00037368597,0.000040217,0.00033264226],"domain_scores_gemma":[0.9994207,0.00005355471,0.00005737341,0.00033335804,0.00006140958,0.000073584764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021856547,0.00019716274,0.000394505,0.00006313533,0.00004393918,0.000013376281,0.00022837144,0.0002325754,0.000030429263],"category_scores_gemma":[0.000035545076,0.0001223602,0.0001262615,0.00014009187,0.00014987291,0.000004160712,0.00022167762,0.000074343814,0.000010614851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026046673,0.000021949683,0.023531282,0.000012021851,0.00047064252,0.000001621388,0.000058162634,0.00009355364,0.9730104,0.000009521201,0.002599272,0.00016549387],"study_design_scores_gemma":[0.00066638,0.00010848387,0.013781108,0.000009855901,0.0002066262,0.0000073908554,0.000023915949,0.00002070687,0.90429497,0.0000053713443,0.08077678,0.00009839035],"about_ca_topic_score_codex":0.00006854634,"about_ca_topic_score_gemma":0.00014203363,"teacher_disagreement_score":0.078177504,"about_ca_system_score_codex":0.000009929272,"about_ca_system_score_gemma":0.000017069253,"threshold_uncertainty_score":0.4989704},"labels":[],"label_agreement":null},{"id":"W2311196695","doi":"10.1101/041996","title":"A CRISPR screen reveals a WNT7B-FZD5 signaling circuit as a therapeutic opportunity in pancreatic cancer","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Pancreatic cancer; Cancer; Biology; Cancer research; Medicine; Genetics; Gene","score_opus":0.022268766698062454,"score_gpt":0.2827150251896252,"score_spread":0.2604462584915628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2311196695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9755889,0.0099383015,0.012324052,0.00021448296,0.0005479014,0.0009152871,0.0002961894,0.000117534975,0.000057361915],"genre_scores_gemma":[0.9957762,0.0017561564,0.0005100222,0.0005171533,0.0007330026,0.00047690864,0.0000018162352,0.00018260727,0.000046158002],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99679184,0.0001872601,0.00067014445,0.0012108975,0.0003358604,0.00080399547],"domain_scores_gemma":[0.9975571,0.00004337001,0.00030520346,0.0013906346,0.00028943986,0.00041425825],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00070266926,0.00069404586,0.00068951794,0.00025124123,0.00009689075,0.00011186461,0.00066483323,0.00076220284,0.00011809332],"category_scores_gemma":[0.00027681387,0.0006896974,0.00023447216,0.0002729441,0.00010059634,0.000010485831,0.00047841945,0.0005683972,0.0000255478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049341663,0.000074720694,0.013936782,0.00029341382,0.0002523813,0.000046236513,0.000012378963,0.00019508674,0.9848562,0.00011322235,0.00015003725,0.000020184338],"study_design_scores_gemma":[0.0011141637,0.00014765444,0.061980985,0.0014788089,0.00023936047,1.5182157e-7,0.0000088543065,0.00012453726,0.9286696,0.000046618476,0.004656792,0.0015324814],"about_ca_topic_score_codex":0.00025708482,"about_ca_topic_score_gemma":0.000021134509,"teacher_disagreement_score":0.056186624,"about_ca_system_score_codex":0.00017915087,"about_ca_system_score_gemma":0.00096519204,"threshold_uncertainty_score":0.9995554},"labels":[],"label_agreement":null},{"id":"W2312204592","doi":"10.5114/bta.2012.46589","title":"VIEWS and NEWS &lt;br&gt; 6th annual International Biomass Conference &amp; Expo • 12th International Wheat Genetics Symposium • Antibodypedia • CNIO and Nature joint events •The first use of anti-cancer engineered T cell therapy in children • The scientific world criticizes the study by Gilles-Eric Séralini et al. concerning health risks arising from genetically modified maize • Whole genome sequencing of circulating DNA in cancer patients.","year":2014,"lang":"en","type":"article","venue":"BioTechnologia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cancer; Library science; Political science; Biology; Genetics","score_opus":0.035523322401326406,"score_gpt":0.31355893892049075,"score_spread":0.27803561651916436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312204592","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914543,0.0038519618,0.0017028109,0.0016282187,0.0002715804,0.0006608432,0.00041520834,0.000011206902,0.000003845206],"genre_scores_gemma":[0.9954669,0.0034830119,0.00053434947,0.00025228303,0.000042550928,0.000036044472,0.00015462942,0.000021896882,0.000008344562],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983393,0.0001168103,0.0005298193,0.00048647,0.00026320928,0.0002644142],"domain_scores_gemma":[0.99915564,0.000064609776,0.00025310562,0.00035793893,0.00013133371,0.000037369668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005082166,0.000229391,0.0002805846,0.000143165,0.00011196394,0.000072258124,0.00043561787,0.00016799975,0.000004760644],"category_scores_gemma":[0.00009200924,0.00015722575,0.00004543752,0.00022977965,0.00024612414,0.000016154347,0.0002918483,0.00034539055,1.08411946e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016999045,0.00009365776,0.25482076,0.000011308507,0.00006938503,1.8732392e-7,0.0005718568,0.004687968,0.73877114,0.0000061049373,0.000086042026,0.0008645821],"study_design_scores_gemma":[0.0020841851,0.00025409219,0.82459694,0.00017646543,0.000029154286,0.0000027740946,0.00053878507,0.009349575,0.159101,0.000023954286,0.003452552,0.00039051718],"about_ca_topic_score_codex":0.00093392166,"about_ca_topic_score_gemma":0.0010837915,"teacher_disagreement_score":0.57967013,"about_ca_system_score_codex":0.000053616455,"about_ca_system_score_gemma":0.000071225026,"threshold_uncertainty_score":0.641148},"labels":[],"label_agreement":null},{"id":"W2315398962","doi":"10.1021/acschembio.5b00971","title":"Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition","year":2016,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Argonne National Laboratory; Brookhaven National Laboratory; Institute of Infection and Immunity; Canadian Institutes of Health Research; Government of Canada; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences; U.S. Department of Energy","keywords":"Proteases; Biology; Protease; Caspase; Reprogramming; Cell biology; Peptide library; Directed evolution; Computational biology; Biochemistry; Cell; Enzyme; Mutant; Programmed cell death; Peptide sequence; Apoptosis; Gene","score_opus":0.02421095145604824,"score_gpt":0.29970667233177556,"score_spread":0.2754957208757273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2315398962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9237743,0.0008130549,0.07450047,0.00040775075,0.000072962874,0.00024079914,0.00010662929,0.000033248696,0.000050758834],"genre_scores_gemma":[0.99582636,0.00056913827,0.0026821692,0.000035724548,0.00024733678,0.00011661674,0.00040663677,0.00001687266,0.00009915303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990384,0.000021894217,0.00018448617,0.00041696546,0.00002979375,0.0003084584],"domain_scores_gemma":[0.9996202,0.00005412923,0.000055657816,0.000114952556,0.000085682186,0.000069382266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012791507,0.0001255633,0.000108899614,0.000027065453,0.00009137776,0.000015552348,0.00006769081,0.0001767699,0.000006220409],"category_scores_gemma":[0.00011965984,0.00010331371,0.000048467005,0.00005293894,0.00012998223,0.0000052073456,0.000041330404,0.00005284144,0.000003851874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005195888,0.000023821553,0.00036268373,0.000008348765,0.000023000222,2.2471306e-7,0.000008708681,0.000001236054,0.9570805,0.00011848219,0.0011507446,0.041170333],"study_design_scores_gemma":[0.0005079028,0.00015601287,0.00010302112,0.000010365669,0.000014417614,0.000036709167,0.000018670677,0.000029102686,0.9694411,0.0013663098,0.028145617,0.0001707546],"about_ca_topic_score_codex":0.00001146639,"about_ca_topic_score_gemma":0.00001253449,"teacher_disagreement_score":0.07205203,"about_ca_system_score_codex":0.000018566783,"about_ca_system_score_gemma":0.000013497027,"threshold_uncertainty_score":0.4213011},"labels":[],"label_agreement":null},{"id":"W2317565849","doi":"10.3389/fgene.2016.00043","title":"Gene Targeting Using Homologous Recombination in Embryonic Stem Cells: The Future for Behavior Genetics?","year":2016,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"CRISPR; Genome editing; Homologous recombination; Gene targeting; Embryonic stem cell; Gene; Cas9; Genetics; Computational biology; Biology; Function (biology); Geneticist; Neuroscience","score_opus":0.016764314905104726,"score_gpt":0.3155583547984116,"score_spread":0.2987940398933069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2317565849","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033761559,0.96358687,0.027075823,0.000019495874,0.003949526,0.0018453978,0.00012583459,0.0000120235145,0.000008894269],"genre_scores_gemma":[0.0002889552,0.9764938,0.021290302,0.000022281476,0.0009230122,0.0004152431,0.00017555758,0.00015617223,0.00023470742],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974052,0.00019508737,0.0007900531,0.0007732714,0.00017363188,0.0006627679],"domain_scores_gemma":[0.99879354,0.000035256446,0.00031289586,0.0006941224,0.00008231451,0.000081859966],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045559736,0.0005624981,0.0008716432,0.00025644075,0.00009709686,0.000046082987,0.0006879313,0.0008413054,0.0000034041088],"category_scores_gemma":[0.000016550679,0.00044388179,0.00037964454,0.00026364694,0.000081149345,0.0000033375377,0.00020863324,0.00032876316,0.0000022165716],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013596898,0.000059930397,0.00025329672,0.0012201191,0.000081344086,0.000009306126,0.000040894367,0.0008553467,0.0021066936,0.0000019332417,0.0025447968,0.99281275],"study_design_scores_gemma":[0.0006843848,0.00018593413,0.000023282028,0.000905186,0.00032411714,0.000034255005,0.00019383575,0.00075011665,0.0076929433,0.000034789937,0.98837,0.00080113334],"about_ca_topic_score_codex":0.0000025649063,"about_ca_topic_score_gemma":0.000023063678,"teacher_disagreement_score":0.9920116,"about_ca_system_score_codex":0.0002027525,"about_ca_system_score_gemma":0.00026516407,"threshold_uncertainty_score":0.9998013},"labels":[],"label_agreement":null},{"id":"W2319061195","doi":"10.1016/j.celrep.2016.03.042","title":"CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape","year":2016,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Ministry of Science and Technology of the People's Republic of China; Cancer Research UK","keywords":"CRISPR; Subgenomic mRNA; Cas9; Biology; Indel; Genetics; Viral replication; Genome editing; DNA; Guide RNA; Virology; Computational biology; Virus; Gene","score_opus":0.00785290422592249,"score_gpt":0.2681885754275171,"score_spread":0.2603356712015946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2319061195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9722865,0.0005744112,0.024591835,0.00021580556,0.00011182201,0.0001465735,0.0000052410796,0.000026107971,0.0020416647],"genre_scores_gemma":[0.9961902,0.00019013442,0.0008144547,0.000072974544,0.00011853517,0.000026640888,0.000063121806,0.000021197187,0.0025027515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991221,0.0000129321315,0.00021928569,0.00041680716,0.000069296184,0.00015961986],"domain_scores_gemma":[0.999275,0.0000074709264,0.00009300847,0.00049619033,0.000048159745,0.000080142985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011643496,0.00011315353,0.00008691316,0.00002879714,0.000058293608,0.00002336941,0.00004281339,0.00008521936,0.000027409022],"category_scores_gemma":[0.00006947447,0.000092435104,0.000039395127,0.000036135247,0.00004062573,0.000005374943,0.000059915896,0.00003426737,0.000007660004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000060827824,0.000015382584,0.0021280618,0.000010776115,0.000007848542,0.000019113391,0.000031675067,0.00003071012,0.9925262,0.0000060205,0.0017543889,0.0034637828],"study_design_scores_gemma":[0.00019882566,0.000049195347,0.008056457,0.000010507307,0.000013914258,0.000114445436,0.000020684598,0.000029733961,0.96573466,0.000093146904,0.02552875,0.00014965438],"about_ca_topic_score_codex":0.000004675551,"about_ca_topic_score_gemma":0.000004607845,"teacher_disagreement_score":0.026791472,"about_ca_system_score_codex":0.000008404487,"about_ca_system_score_gemma":0.000031298707,"threshold_uncertainty_score":0.37693942},"labels":[],"label_agreement":null},{"id":"W2321701337","doi":"10.1080/21624054.2016.1156835","title":"Hitting two birds with one stone: The unforeseen consequences of nested gene knockouts in<i>Caenorhabditis elegans</i>","year":2016,"lang":"en","type":"article","venue":"Worm","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Gene; Biology; Genetics; Gene knockout; Gene prediction; Phenotype; Intron; Pair-rule gene; Genome; Computational biology; Regulation of gene expression; Regulator gene","score_opus":0.0070650341378523124,"score_gpt":0.2628042097406763,"score_spread":0.255739175602824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2321701337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925044,0.00076775707,0.005195049,0.0005269949,0.000054505097,0.00013937984,0.000016544978,0.000011700172,0.0007836438],"genre_scores_gemma":[0.9984095,0.00014120669,0.0008424907,0.00007728259,0.00010145223,0.00001676874,0.0000066673806,0.000016984253,0.00038762816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992899,0.000021479382,0.00017893217,0.0001813478,0.00011676146,0.00021162386],"domain_scores_gemma":[0.99954474,0.000029633451,0.000061376784,0.000272009,0.000052495583,0.00003973584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014280254,0.00010948556,0.00012652976,0.00003491568,0.000033410335,0.000008270129,0.00017506821,0.000053037613,0.000016010175],"category_scores_gemma":[0.000039512768,0.00006322201,0.00003319115,0.00012871125,0.00016539596,0.0000032586047,0.000051700907,0.000051165407,0.0000023048356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038451155,0.000017015182,0.012704246,0.000010892911,0.000029967377,0.00000428105,0.00007761655,0.00023250961,0.98191285,0.00006194464,0.00008997314,0.004820279],"study_design_scores_gemma":[0.00071059953,0.00015337084,0.010515911,0.00007536813,0.0000132703535,0.000027652146,0.000070103815,0.000012038557,0.98544204,0.000042965814,0.0028061944,0.00013045897],"about_ca_topic_score_codex":0.00013043992,"about_ca_topic_score_gemma":0.0005281411,"teacher_disagreement_score":0.005905094,"about_ca_system_score_codex":0.000010301834,"about_ca_system_score_gemma":0.00006287615,"threshold_uncertainty_score":0.25781187},"labels":[],"label_agreement":null},{"id":"W2321748099","doi":"10.3791/53552","title":"Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"Enhancer; Biology; CRISPR; Cas9; Genetics; Genome editing; Gene; Enhancer RNAs; Genome; CRISPR interference; Regulation of gene expression; Gene expression","score_opus":0.018764297673081177,"score_gpt":0.3979786295356905,"score_spread":0.37921433186260933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2321748099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94714934,0.0011799765,0.050958514,0.00004347728,0.0004322874,0.00021377385,0.0000042721326,0.0000065448135,0.000011822716],"genre_scores_gemma":[0.99795544,0.00016979687,0.0010702398,0.00010392687,0.00027739347,0.000031260937,0.0000021827989,0.000028488124,0.00036125936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987777,0.00010101383,0.00047162702,0.00020800561,0.000215173,0.00022648534],"domain_scores_gemma":[0.99939525,0.000016234233,0.00014978519,0.000187391,0.000115907904,0.00013542545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002875575,0.00015790998,0.00021639859,0.00014244526,0.000045179844,0.00002200325,0.00014926253,0.0000796533,0.00004646824],"category_scores_gemma":[0.000031805575,0.0001202558,0.00008466923,0.00010995652,0.000009573392,0.000009733272,0.00006847718,0.000072491755,0.000014044366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019468184,0.0002936144,0.0005894796,0.000003122086,0.00009241246,0.0000068176973,0.00037457116,0.0005741098,0.99556655,9.658979e-7,0.00051519286,0.0017884854],"study_design_scores_gemma":[0.0024944334,0.001053696,0.0004530273,0.000027812424,0.000016333548,0.000006555031,0.000703293,0.000069460024,0.99296135,9.74493e-7,0.0020579004,0.00015514427],"about_ca_topic_score_codex":0.0000071960944,"about_ca_topic_score_gemma":0.000012511279,"teacher_disagreement_score":0.05080612,"about_ca_system_score_codex":0.000058113998,"about_ca_system_score_gemma":0.000044376025,"threshold_uncertainty_score":0.4903889},"labels":[],"label_agreement":null},{"id":"W2321813948","doi":"10.1038/protex.2015.007","title":"Ultra-low-input native ChIP-seq for rare cell populations","year":2015,"lang":"en","type":"article","venue":"Protocol Exchange","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Chip; Computational biology; Biology; Computer science; Telecommunications","score_opus":0.0404860428240576,"score_gpt":0.364777399994359,"score_spread":0.3242913571703014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2321813948","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.043301426,0.00065837667,0.2675982,0.00067216443,0.0009473351,0.65675706,0.0004355774,0.00022296123,0.029406914],"genre_scores_gemma":[0.3181503,0.0000033575725,0.006402924,0.0001949116,0.00091293175,0.6708029,0.0002691028,0.000062402214,0.0032012025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925756,0.000020147705,0.00014452847,0.00025122502,0.00009963764,0.00022688377],"domain_scores_gemma":[0.99947095,0.0000060820535,0.000048190224,0.00022537635,0.00012852596,0.00012087935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013206001,0.00014128312,0.00010558416,0.000038449907,0.000057615347,0.000019651747,0.00012788014,0.00010588977,0.000022500499],"category_scores_gemma":[0.00007147066,0.00013680356,0.00007150632,0.000069462614,0.000019762989,0.0000036278182,0.000041199473,0.00005140355,0.000009886849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007164404,0.00060003623,0.003250576,0.001513169,0.000093491595,0.00000653118,0.0026170248,0.0022036582,0.8895105,0.00040361224,0.085072115,0.014012858],"study_design_scores_gemma":[0.002113116,0.0004916631,0.00044233692,0.000022611302,0.000011473011,0.0000039209767,0.00012300491,0.00040106897,0.685986,0.00032194852,0.30978337,0.00029946835],"about_ca_topic_score_codex":0.0000097647535,"about_ca_topic_score_gemma":0.000031977605,"teacher_disagreement_score":0.27484888,"about_ca_system_score_codex":0.000017394208,"about_ca_system_score_gemma":0.00004871085,"threshold_uncertainty_score":0.5578687},"labels":[],"label_agreement":null},{"id":"W2323406596","doi":"10.1534/g3.115.024257","title":"Chromoanasynthetic Genomic Rearrangement Identified in a <i>N</i>-Ethyl-<i>N</i>-Nitrosourea (ENU) Mutagenesis Screen in <i>Caenorhabditis elegans</i>","year":2015,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Caenorhabditis elegans; Biology; Mutagenesis; Genetics; Point mutation; Phenotype; Ethyl methanesulfonate; Mutagen; Mutation; Mutant; Nitrosourea; Genome; Gene; Molecular biology; Carcinogen","score_opus":0.014831755978391873,"score_gpt":0.2774705820005817,"score_spread":0.26263882602218985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2323406596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7084284,0.28654024,0.0024121276,0.00013471252,0.0004993669,0.0007162777,0.0000942153,0.000040496132,0.0011341788],"genre_scores_gemma":[0.9213203,0.072955534,0.0036465863,0.00032536776,0.0005740427,0.00015295247,0.000286583,0.00016022933,0.0005784051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99644357,0.00017866961,0.0008684417,0.0010256445,0.00045591596,0.0010277575],"domain_scores_gemma":[0.99819064,0.000023391553,0.00015755312,0.0011028559,0.00013715882,0.00038837644],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007142815,0.00058316474,0.0005550194,0.00059125887,0.00007353667,0.000096393465,0.0007307496,0.0003576453,0.000036220998],"category_scores_gemma":[0.000021569405,0.00067702826,0.00019453488,0.0007653,0.00013267019,0.000011119582,0.00042907335,0.00023221996,0.000071047536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014030807,0.00018788088,0.029966174,0.000073103794,0.0000929046,0.0001005538,0.0005276981,0.029922683,0.8051102,0.000008497681,0.0014203712,0.13244961],"study_design_scores_gemma":[0.005142834,0.00075496803,0.02075541,0.000092608396,0.00012821592,0.00016433651,0.001082578,0.0015535709,0.511814,0.00022696727,0.45632908,0.0019554181],"about_ca_topic_score_codex":0.00034792893,"about_ca_topic_score_gemma":0.0026382015,"teacher_disagreement_score":0.4549087,"about_ca_system_score_codex":0.00013538216,"about_ca_system_score_gemma":0.00024450777,"threshold_uncertainty_score":0.9995681},"labels":[],"label_agreement":null},{"id":"W2324329782","doi":"10.1016/j.exphem.2014.07.253","title":"Delineating key MEIS1 cis-regulatory elements through CRISPR/Cas9 mediated targeting","year":2014,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"CRISPR; Key (lock); Computational biology; Biology; Genetics; Gene; Ecology","score_opus":0.008090483524326104,"score_gpt":0.3147291680672937,"score_spread":0.30663868454296755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2324329782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94077265,0.012667848,0.042285718,0.00011184826,0.00069032656,0.00025874507,0.000008832375,0.000091077236,0.0031129234],"genre_scores_gemma":[0.987696,0.000029850102,0.011046117,0.00047416298,0.00031318932,0.00005085878,0.00022176957,0.00005229777,0.00011575024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983629,0.000079052,0.0004534526,0.00047652345,0.0001611615,0.00046689282],"domain_scores_gemma":[0.99936754,0.000028617276,0.0001080405,0.00034335852,0.000047085196,0.00010534617],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019935955,0.0002656799,0.00028296933,0.00003788703,0.00013414625,0.000015048484,0.00021671488,0.00020120606,0.00013457915],"category_scores_gemma":[0.00011963379,0.00027453402,0.000101871425,0.000071824594,0.0000811572,0.000007016185,0.00020324232,0.00010975779,0.00005686137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043241744,0.000098042845,0.0020279456,0.000028178472,0.000062236984,0.00000585526,0.0003353747,0.00014884525,0.9899274,0.0028554546,0.004177878,0.0002895646],"study_design_scores_gemma":[0.0007793022,0.00022368382,0.00009936289,0.000014250588,0.000009116225,0.000060637227,0.0005598464,0.0015067143,0.968276,0.000038863935,0.028133785,0.00029842957],"about_ca_topic_score_codex":0.000018147986,"about_ca_topic_score_gemma":0.0000064757683,"teacher_disagreement_score":0.04692332,"about_ca_system_score_codex":0.000022034836,"about_ca_system_score_gemma":0.00002151218,"threshold_uncertainty_score":0.9999707},"labels":[],"label_agreement":null},{"id":"W2324574836","doi":"10.1007/978-3-319-19944-3_21","title":"RNA In situ Hybridization","year":2015,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"In situ hybridization; In situ; Biology; Computational biology; Chemistry; Genetics; Messenger RNA; Gene","score_opus":0.013477716975401684,"score_gpt":0.2787551826611864,"score_spread":0.2652774656857847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2324574836","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00096311053,0.0023961612,0.0070800837,0.00002809357,0.00014947646,0.000107195774,0.0000064891224,0.000012324713,0.98925704],"genre_scores_gemma":[0.19329105,0.0005237486,0.0005057755,0.00007536338,0.00035254646,0.0000041739563,0.00039721275,0.000051423696,0.8047987],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994726,0.0000025480895,0.00013320456,0.00021111594,0.00008060747,0.000099917954],"domain_scores_gemma":[0.9996743,0.0000016052755,0.000026525082,0.00020630479,0.000044196102,0.000047035115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006216031,0.00013979385,0.00011177008,0.000048949518,0.0000064481865,0.0000070830233,0.000077218654,0.0002048743,0.00007893007],"category_scores_gemma":[0.000012315267,0.00014425702,0.000042951186,0.0000085549245,0.000012666573,5.2366124e-7,0.000057054123,0.000075268086,0.000039017486],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006420003,0.000037050562,0.000068676716,0.00011318301,0.00013256371,0.0000458199,0.000057483925,0.004298468,0.81422144,0.024943858,0.12656264,0.029454611],"study_design_scores_gemma":[0.0002933963,0.00008203155,0.000035338984,0.0000308391,0.000012886995,0.000009731282,0.000004826219,0.00003828883,0.07657479,0.0009375275,0.9216433,0.0003370556],"about_ca_topic_score_codex":0.000004005693,"about_ca_topic_score_gemma":0.0001012192,"teacher_disagreement_score":0.79508066,"about_ca_system_score_codex":0.000014439477,"about_ca_system_score_gemma":0.000043262768,"threshold_uncertainty_score":0.58826303},"labels":[],"label_agreement":null},{"id":"W2325577790","doi":"10.1111/odi.12487","title":"<scp>CRISPR</scp>: express delivery to any <scp>DNA</scp> address","year":2016,"lang":"en","type":"review","venue":"Oral Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"CRISPR; Genome editing; Function (biology); Computational biology; Biology; Genetics; Gene","score_opus":0.019795230060980544,"score_gpt":0.33184950018502185,"score_spread":0.3120542701240413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2325577790","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022821338,0.99220735,0.001173714,0.000006450842,0.0006045875,0.0007552127,0.0018421728,0.00008482319,0.0010435572],"genre_scores_gemma":[0.0010848164,0.98914593,0.00023296809,0.00015511061,0.0012326495,0.00035799172,0.0009615953,0.00018661814,0.0066422867],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971265,0.00013040316,0.0005335025,0.0010396085,0.00031770382,0.0008522434],"domain_scores_gemma":[0.9977597,0.00016042918,0.00017363552,0.0010524504,0.00012911696,0.00072467513],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009717784,0.00080163917,0.0011093984,0.00017008097,0.00011185998,0.00011235165,0.0008052059,0.00048509974,0.000035048954],"category_scores_gemma":[0.00065854343,0.0006513351,0.0007939626,0.00020607504,0.000083085615,0.000009808936,0.00057583966,0.00017391899,0.00031917382],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009322624,0.00030552878,0.00018163703,0.009965649,0.00080670475,0.00012309251,0.000056119814,0.00006219941,0.006839556,0.00003639561,0.43174776,0.549866],"study_design_scores_gemma":[0.00024144028,0.00013975457,0.00013742522,0.0028607966,0.0005299443,0.000016660715,0.000037256734,0.0000015055259,0.0026336764,0.000009289911,0.9931905,0.00020174208],"about_ca_topic_score_codex":0.000012578716,"about_ca_topic_score_gemma":0.0000076192314,"teacher_disagreement_score":0.56144273,"about_ca_system_score_codex":0.00004373789,"about_ca_system_score_gemma":0.00024145575,"threshold_uncertainty_score":0.9995938},"labels":[],"label_agreement":null},{"id":"W2330198637","doi":"10.1016/j.cjca.2013.07.367","title":"Mutagenic Gene Trapping to Study Novel Genes in Zebrafish Cardiovascular Development","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Zebrafish; Gene; Mutant; Genetics; Computational biology; Medicine; Biology; Bioinformatics","score_opus":0.011404132774088785,"score_gpt":0.23784298160651215,"score_spread":0.22643884883242338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2330198637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94894636,0.0031702695,0.04693235,0.00007388432,0.0003605759,0.0002684793,0.000002677112,0.0000018358717,0.00024355939],"genre_scores_gemma":[0.9969999,0.000031717504,0.0023020413,0.000089293404,0.0005070022,0.000023109124,0.00000418186,0.000019963598,0.000022775524],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989124,0.000060781258,0.00036316275,0.00020506026,0.00009525185,0.00036336994],"domain_scores_gemma":[0.99918395,0.0000050538556,0.000041614476,0.0002458913,0.00012821637,0.00039525257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041564295,0.00014306762,0.00035926272,0.00024989006,0.00004817639,0.000020111473,0.000249362,0.0001071846,0.000010357831],"category_scores_gemma":[0.0000535521,0.00014461114,0.00019190107,0.00011745392,0.000023609487,0.0000040067935,0.000030074254,0.00011746725,0.000007893521],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026565656,0.000022946262,0.060057282,0.000019900683,0.0025987905,0.00027446868,0.0012819425,0.27474743,0.60844463,0.0000070106016,0.0020207134,0.05049831],"study_design_scores_gemma":[0.0026542537,0.0007639506,0.6022847,0.00002885738,0.00013428584,0.0010803259,0.0016359986,0.000044195644,0.11591969,0.000014227507,0.27471447,0.00072502356],"about_ca_topic_score_codex":0.00048208743,"about_ca_topic_score_gemma":0.0017279835,"teacher_disagreement_score":0.54222745,"about_ca_system_score_codex":0.000057218218,"about_ca_system_score_gemma":0.00044251676,"threshold_uncertainty_score":0.58970714},"labels":[],"label_agreement":null},{"id":"W2334642566","doi":"10.1021/sb500045w","title":"A Multiplexed Transcription Activator-like Effector System for Detecting Specific DNA Sequences","year":2014,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Research Services, University of Calgary; Genome Alberta; Alberta Innovates; Alberta Innovates - Technology Futures","keywords":"DNA; Effector; Biology; DNA binding site; Transcription (linguistics); DNA-binding protein; DNA sequencing; Molecular biology; Genetics; Computational biology; Transcription factor; Promoter; Gene; Cell biology; Gene expression","score_opus":0.011631671004419737,"score_gpt":0.2754598127344996,"score_spread":0.26382814173007985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334642566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8774219,0.0005443862,0.120380014,0.000048028927,0.00093197066,0.00039627336,0.000027508298,0.000063801075,0.00018607327],"genre_scores_gemma":[0.99692446,0.000034349752,0.0022830882,0.000039509934,0.00044396,0.0001337524,0.00006552657,0.000033939723,0.000041402523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878186,0.00011476519,0.00023141873,0.00046358295,0.000051516283,0.00035685985],"domain_scores_gemma":[0.99936354,0.00011239673,0.000070420814,0.00033233975,0.000049608094,0.00007170272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003477092,0.00020675901,0.0002299553,0.000051996645,0.000113711576,0.00001778911,0.00019267098,0.00026743097,0.00000525016],"category_scores_gemma":[0.00012136768,0.0001856428,0.0001246483,0.000057588368,0.000082244886,0.00000271213,0.000024255029,0.000078677556,0.000011228221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006995763,0.000013001167,0.00014560118,0.00008306825,0.000035580764,2.4276494e-7,0.000051477266,0.00009652922,0.9854434,0.00015614415,0.000039539907,0.0138654215],"study_design_scores_gemma":[0.00058158155,0.00041795132,0.00018956422,0.00003465805,0.000022671795,0.00003169764,0.0000989638,0.00047750864,0.95973474,0.000038318743,0.038137853,0.00023447566],"about_ca_topic_score_codex":0.000013238998,"about_ca_topic_score_gemma":0.000012910508,"teacher_disagreement_score":0.11950253,"about_ca_system_score_codex":0.00002345585,"about_ca_system_score_gemma":0.000015873416,"threshold_uncertainty_score":0.75702935},"labels":[],"label_agreement":null},{"id":"W2338215681","doi":"10.1186/s12859-016-1015-8","title":"BAGEL: a computational framework for identifying essential genes from pooled library screens","year":2016,"lang":"en","type":"article","venue":"BMC Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Computational biology; DNA microarray; Gene; Computer science; Biology; Genetics; Bioinformatics; Gene expression","score_opus":0.01657515414873308,"score_gpt":0.3018650987314888,"score_spread":0.28528994458275575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2338215681","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04372719,0.00045659192,0.95486563,0.000106853455,0.00024230896,0.00018907353,0.00025121297,0.00004245027,0.00011866473],"genre_scores_gemma":[0.15270394,0.000078632744,0.84587044,0.00018607332,0.0005023561,0.000022044676,0.00043078294,0.00003014713,0.00017557794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922645,0.000010111095,0.0002883198,0.00014883051,0.000116172545,0.00021013842],"domain_scores_gemma":[0.9994808,0.000093422575,0.00008110437,0.0002290969,0.000037931797,0.000077652236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058607257,0.00014011517,0.00011908083,0.000042307136,0.00007101714,0.00006150793,0.00017666965,0.00014955628,0.00005127993],"category_scores_gemma":[0.00008013672,0.00011087246,0.00011583884,0.000051065803,0.00003850888,0.000018067323,0.00011682172,0.000037837963,0.000026390471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015084564,0.00046232276,0.040787894,0.001993165,0.00215821,0.000009460006,0.0020464736,0.08496304,0.5888955,0.0295989,0.057851773,0.1897248],"study_design_scores_gemma":[0.0053269877,0.00043052185,0.015792567,0.0005670581,0.00029264085,0.000029288316,0.000854621,0.2711196,0.6229974,0.02620051,0.054605886,0.0017829146],"about_ca_topic_score_codex":0.0000015070239,"about_ca_topic_score_gemma":0.0000038261896,"teacher_disagreement_score":0.18794188,"about_ca_system_score_codex":0.000004843677,"about_ca_system_score_gemma":0.00006150624,"threshold_uncertainty_score":0.45212477},"labels":[],"label_agreement":null},{"id":"W2338782656","doi":"10.1016/j.stem.2016.03.013","title":"Activation of Endogenous Retroviruses in Dnmt1 −/− ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA","year":2016,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; DNA methylation; DNMT1; Endogenous retrovirus; Methyltransferase; Epigenetics; CpG site; DNA methyltransferase; Gene silencing; DNA; Methylation; Psychological repression; DNA demethylation; Cell biology; Ectopic expression; Genetics; Molecular biology; Gene; Genome; Gene expression","score_opus":0.01285154661591605,"score_gpt":0.25362209896713495,"score_spread":0.24077055235121889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2338782656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99542075,0.00059431593,0.0032239538,0.000013887253,0.00007307623,0.00020703678,0.000040983883,0.0000109486555,0.0004150529],"genre_scores_gemma":[0.9990177,0.0003009018,0.00018857856,0.000010838515,0.00002549862,0.000009890837,0.00008718293,0.000023217035,0.00033616924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902236,0.000044298933,0.00033582604,0.0002856609,0.00012338454,0.00018845548],"domain_scores_gemma":[0.99940544,0.00004474288,0.00014870553,0.00028213242,0.000054104436,0.000064891785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015832543,0.00013673826,0.00018270923,0.00009496663,0.000018381208,0.0000043303025,0.00012398606,0.00016243056,0.000012209284],"category_scores_gemma":[0.00003383082,0.00011237896,0.000051516203,0.00017457685,0.000023699457,0.00000611536,0.000075400174,0.000047428035,0.0000051699494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007889517,0.00007292243,0.0035802808,0.000104323095,0.000007378549,6.40147e-7,0.00017123947,0.00019684708,0.9939836,4.6903165e-7,0.00023224858,0.0015711572],"study_design_scores_gemma":[0.0005736005,0.0002009555,0.0005106386,0.000096269476,0.000007932245,5.7773997e-7,0.00013571896,0.000024938592,0.9974015,0.0000021237238,0.0009071569,0.00013859425],"about_ca_topic_score_codex":0.00004002256,"about_ca_topic_score_gemma":0.0000049810797,"teacher_disagreement_score":0.003596978,"about_ca_system_score_codex":0.000027638724,"about_ca_system_score_gemma":0.00002892225,"threshold_uncertainty_score":0.4582681},"labels":[],"label_agreement":null},{"id":"W2340356391","doi":"10.1038/gt.2016.36","title":"Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice","year":2016,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Biology; Frataxin; In vivo; Transcription (linguistics); Molecular biology; Gene; Effector; Haploinsufficiency; Gene expression; Messenger RNA; Activator (genetics); Transcription activator-like effector nuclease; Cell biology; Genetics; Genome editing; CRISPR; Iron-binding proteins","score_opus":0.014019029171785163,"score_gpt":0.3076732432123441,"score_spread":0.29365421404055897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340356391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889456,0.00039416904,0.010108321,0.0000753538,0.000040523915,0.0003500949,0.000016496804,0.000005009326,0.000064414504],"genre_scores_gemma":[0.991711,0.00009879954,0.007649077,0.00015127915,0.00007788709,0.0001111109,0.000012938344,0.000019728603,0.0001681481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999235,0.000026697493,0.0002267249,0.00022517065,0.00006654947,0.00021988069],"domain_scores_gemma":[0.9996161,0.000015001648,0.00003471203,0.00025384402,0.000029348881,0.00005098302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003390171,0.000115931914,0.00012332386,0.000057455287,0.000042674656,0.000007901267,0.00020405094,0.000066368215,0.000017881262],"category_scores_gemma":[0.000017728693,0.00007984578,0.00003148439,0.00008229398,0.000018179211,0.0000031610314,0.000042139156,0.000029388546,0.0000012418383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010453441,0.000048588277,0.00049091317,0.000007322664,0.000012810187,6.885909e-7,0.00045819633,0.00014626638,0.98914105,0.00001617403,0.00009875485,0.0094747245],"study_design_scores_gemma":[0.0010595658,0.00014883398,0.0031428959,0.000023810353,0.0000014233242,0.0000015932463,0.00009939531,0.000025541896,0.978129,0.000036566802,0.017197257,0.00013407483],"about_ca_topic_score_codex":0.000061136285,"about_ca_topic_score_gemma":0.0008807732,"teacher_disagreement_score":0.017098501,"about_ca_system_score_codex":0.000019101124,"about_ca_system_score_gemma":0.00005323085,"threshold_uncertainty_score":0.32560164},"labels":[],"label_agreement":null},{"id":"W2340776849","doi":"10.1371/journal.pone.0153901","title":"A Digital PCR-Based Method for Efficient and Highly Specific Screening of Genome Edited Cells","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Cancer Foundation; Alberta Innovates; Alberta Innovates - Health Solutions; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Transcription activator-like effector nuclease; CRISPR; Genome editing; Amplicon; Computational biology; Biology; Digital polymerase chain reaction; Genetics; Cas9; Genome engineering; False positive paradox; Trans-activating crRNA; Gene; Polymerase chain reaction; Computer science","score_opus":0.019872526380018317,"score_gpt":0.25278436344656025,"score_spread":0.23291183706654192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340776849","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44831318,0.0004260554,0.55084074,0.00006481059,0.000020556643,0.00014937902,0.00010445955,0.000007384972,0.00007342207],"genre_scores_gemma":[0.92835134,0.000032504886,0.07110583,0.00001663751,0.00019133187,0.000015224506,0.000032042455,0.000018727136,0.00023637884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994391,0.000007399823,0.00012791783,0.0001971403,0.00008618695,0.00014224967],"domain_scores_gemma":[0.99964625,0.000041325296,0.000035959154,0.00016336577,0.000060339727,0.000052757987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083547646,0.00008647223,0.00012505348,0.000036625337,0.00001874303,0.000010188347,0.00006374032,0.00005527879,0.0000053759077],"category_scores_gemma":[0.000033696888,0.00006886048,0.000044381137,0.000035898156,0.000028246935,0.0000011875079,0.00003534542,0.000018405879,0.0000010557175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007179118,0.00012339756,0.000078522324,0.000050182134,0.00006344101,2.8202592e-7,0.0000072362172,0.00044208136,0.9962166,0.0000070868273,0.00004057573,0.002898824],"study_design_scores_gemma":[0.00071490026,0.0002649092,0.00032509243,0.000045510067,0.000029492903,4.3422372e-7,0.0000070539672,0.0017139553,0.9939677,0.000004131981,0.0028186643,0.00010813998],"about_ca_topic_score_codex":5.00805e-7,"about_ca_topic_score_gemma":2.7390098e-7,"teacher_disagreement_score":0.48003814,"about_ca_system_score_codex":0.0000038418125,"about_ca_system_score_gemma":0.0000098192595,"threshold_uncertainty_score":0.28080487},"labels":[],"label_agreement":null},{"id":"W2341041867","doi":"10.1016/j.theriogenology.2016.04.028","title":"New insights and current tools for genetically engineered (GE) sheep and goats","year":2016,"lang":"en","type":"review","venue":"Theriogenology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Biotechnology and Biological Sciences Research Council","keywords":"CRISPR; Genome editing; Genetically modified organism; Somatic cell nuclear transfer; Transgenesis; Biology; Cas9; Transgene; Transcription activator-like effector nuclease; Genetically engineered; Genome engineering; Computational biology; Biomedicine; Synthetic biology; Biotechnology; Zygote; Genome; Genetics; Zinc finger nuclease; Homologous recombination; Reproductive technology; Gene","score_opus":0.02609868731300059,"score_gpt":0.328304381838213,"score_spread":0.3022056945252124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2341041867","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00037584404,0.95853347,0.03992879,0.000023067782,0.0003349285,0.0006482839,0.000058397596,0.000019067584,0.0000781301],"genre_scores_gemma":[0.00019484585,0.9963702,0.0022395565,0.000018392904,0.0006324717,0.00010186808,0.00011520278,0.000075927834,0.0002515155],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99868524,0.00004179127,0.0003260542,0.00055058266,0.0000512835,0.00034504736],"domain_scores_gemma":[0.9992793,0.00007319101,0.000079427125,0.00037234885,0.00003204827,0.00016366616],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006805392,0.00039550572,0.000729987,0.00007482844,0.000042960317,0.00003363627,0.00019646947,0.00046448354,0.00002080947],"category_scores_gemma":[0.00007211478,0.0002975555,0.00015663386,0.00004342037,0.00007614626,0.0000024531605,0.00018684844,0.000106563646,0.000009229858],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000116408255,0.0000067799733,5.527181e-7,0.0010992206,0.00014764363,0.0000011353476,0.000020898386,6.647078e-7,0.0041739447,0.00025549627,0.00024895932,0.99403304],"study_design_scores_gemma":[0.0003872875,0.00024475827,0.000009889398,0.0004880644,0.00019532615,0.000074119474,0.0000027063027,0.000003997642,0.0005876295,0.00015867347,0.9974707,0.0003768469],"about_ca_topic_score_codex":0.000001551131,"about_ca_topic_score_gemma":0.00000569524,"teacher_disagreement_score":0.99722177,"about_ca_system_score_codex":0.000011684585,"about_ca_system_score_gemma":0.00013290899,"threshold_uncertainty_score":0.99994767},"labels":[],"label_agreement":null},{"id":"W2343746986","doi":"10.3389/fpls.2016.00532","title":"The Rice Eukaryotic Translation Initiation Factor 3 Subunit f (OseIF3f) Is Involved in Microgametogenesis","year":2016,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Botany, Chinese Academy of Sciences; Agriculture and Agri-Food Canada; Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences","keywords":"Eukaryotic translation; Protein subunit; Translation (biology); Initiation factor; Biology; Eukaryotic translation initiation factor 4 gamma; EIF4A1; Genetics; Cell biology; Computational biology; Gene; Messenger RNA","score_opus":0.013899010066978032,"score_gpt":0.25823067026372715,"score_spread":0.24433166019674912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2343746986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96256703,0.0011877724,0.035255875,0.00027669044,0.0004378536,0.00013213702,0.00004037872,0.000005965529,0.000096272204],"genre_scores_gemma":[0.9972891,0.0008493101,0.0016786102,0.000064353844,0.000030379815,0.00000931853,0.000008331153,0.000005901668,0.00006465357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991685,0.000026090522,0.00015948305,0.00025090695,0.0001438897,0.00025113925],"domain_scores_gemma":[0.9996879,0.000028056815,0.000033687276,0.00018344937,0.000025642077,0.000041253883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031888764,0.000085203705,0.00007181672,0.00012225188,0.00007864881,0.000025698717,0.0002626307,0.000055811717,0.0000024189214],"category_scores_gemma":[0.00007888199,0.000057660993,0.000023243807,0.0003076823,0.00013722859,0.000013696813,0.000029420562,0.000040957242,0.0000025266065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036463665,0.000012875414,0.11952887,0.0000066474695,0.0000040651817,0.0000016094046,0.00024370213,0.000075437325,0.86123747,0.0000071284426,0.00053180655,0.01831391],"study_design_scores_gemma":[0.00055092823,0.000051569965,0.2236541,0.000034214256,0.000004130989,0.0000037292402,0.00021449925,0.0015838223,0.7684909,0.00010819276,0.0051102196,0.00019370417],"about_ca_topic_score_codex":0.000016318998,"about_ca_topic_score_gemma":0.000119856086,"teacher_disagreement_score":0.10412524,"about_ca_system_score_codex":0.00004048352,"about_ca_system_score_gemma":0.00008135485,"threshold_uncertainty_score":0.23513469},"labels":[],"label_agreement":null},{"id":"W2344328354","doi":"10.1186/s13036-016-0028-1","title":"Seamless site-directed mutagenesis of the Saccharomyces cerevisiae genome using CRISPR-Cas9","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies; Concordia University","keywords":"CRISPR; Genome editing; Saccharomyces cerevisiae; Computational biology; Genome; Cas9; Mutagenesis; Point mutation; Genetics; Gene; Biology; Genome engineering; Computer science; Mutation","score_opus":0.014900123698700241,"score_gpt":0.27079526475690263,"score_spread":0.2558951410582024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344328354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9513203,0.0023505285,0.045904905,0.00006442154,0.0002537962,0.000066636836,0.000014664883,0.000010502505,0.000014241894],"genre_scores_gemma":[0.99539524,0.0004268671,0.0038573146,0.000019360408,0.00025966627,0.0000011153098,0.0000011114392,0.000016569178,0.000022753653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990658,0.00003668372,0.00040766786,0.00014556307,0.00013093224,0.00021331247],"domain_scores_gemma":[0.999361,0.00004370583,0.00018953376,0.00020385649,0.00011982822,0.000082085404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023961208,0.00015780894,0.0002622277,0.000059334856,0.000029898105,0.00000900858,0.00028594665,0.00014224823,0.000027974162],"category_scores_gemma":[0.0002608089,0.000081235245,0.00023519374,0.00013359869,0.000042713717,0.0000053141807,0.000118340504,0.00009262241,9.083008e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024512117,0.000017265214,0.0025075884,0.000020987334,0.00006346792,0.0000039166334,0.000014372024,0.010644792,0.9857332,0.0000075341427,0.000016132713,0.00094624545],"study_design_scores_gemma":[0.0005323958,0.00024573092,0.049478844,0.00014380267,0.000046807214,0.00019443774,0.000024076486,0.0010002851,0.9435733,0.000008315986,0.004516429,0.00023560475],"about_ca_topic_score_codex":0.000002390314,"about_ca_topic_score_gemma":5.263205e-7,"teacher_disagreement_score":0.046971254,"about_ca_system_score_codex":0.000022757273,"about_ca_system_score_gemma":0.000030275805,"threshold_uncertainty_score":0.3312677},"labels":[],"label_agreement":null},{"id":"W2346776360","doi":"10.1111/joac.12161","title":"The <i>Red de Semillas Libres</i>: Contesting Biohegemony in Colombia","year":2016,"lang":"en","type":"article","venue":"Journal of Agrarian Change","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Cognitive reframing; Commodification; Technoscience; Intellectual property; Sovereignty; Narrative; Ethnography; Sociology; Food sovereignty; Political science; Social science; Agriculture; Law; Economy; Anthropology; Biology; Economics; Food security; Ecology","score_opus":0.015974467416802567,"score_gpt":0.28436596825426524,"score_spread":0.26839150083746266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346776360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9852904,0.0051719807,0.0018103932,0.0062507708,0.00052192266,0.00014818671,0.000009972352,0.0000065605773,0.00078980473],"genre_scores_gemma":[0.99786544,0.0009083173,0.0002819999,0.00017495746,0.0005631946,0.0000044418102,8.993231e-7,0.0000098613855,0.00019089018],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993698,0.00003921203,0.00021955941,0.00008111229,0.00008171165,0.00020860617],"domain_scores_gemma":[0.9995771,0.00005932933,0.00011354003,0.00011944598,0.000055854725,0.00007470747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038646755,0.00007971387,0.00010165418,0.00003927092,0.00004034809,0.000021400496,0.00017277877,0.00007208337,0.000004500203],"category_scores_gemma":[0.00022460854,0.000045931716,0.00006745659,0.00006571294,0.00003192537,0.0000048007,0.000043801734,0.00007382797,0.0000013810217],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001004123,0.000022478991,0.019577928,0.000008349178,0.000036158057,0.00003496281,0.00016030871,0.0000141274195,0.9420531,0.00001773084,0.01275999,0.025214452],"study_design_scores_gemma":[0.0035995832,0.0010715957,0.12587303,0.00037676725,0.000036854137,0.00063415186,0.00027885954,0.000100719546,0.41885498,0.00025774416,0.44851455,0.00040115393],"about_ca_topic_score_codex":0.00001204194,"about_ca_topic_score_gemma":0.00010340639,"teacher_disagreement_score":0.5231981,"about_ca_system_score_codex":0.000018080944,"about_ca_system_score_gemma":0.000043664557,"threshold_uncertainty_score":0.18730411},"labels":[],"label_agreement":null},{"id":"W2346982267","doi":"10.1128/mbio.00202-16","title":"Programming Native CRISPR Arrays for the Generation of Targeted Immunity","year":2016,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Acquired immune system; Genome editing; Biology; Computational biology; Cas9; Plasmid; Immunity; Genome; Genetics; Gene; Immune system","score_opus":0.018540203425942637,"score_gpt":0.3034265592294892,"score_spread":0.28488635580354654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346982267","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3027353,0.0009498324,0.6954857,0.00023996255,0.00018562026,0.00027896403,0.000022401124,0.000007803175,0.00009439646],"genre_scores_gemma":[0.9964391,0.000056889137,0.0030363665,0.000023475559,0.00017991412,0.000047274087,0.00002521034,0.00000845592,0.00018333968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99966496,0.000012532516,0.00009019633,0.000093899755,0.00004078516,0.00009760444],"domain_scores_gemma":[0.99969274,0.000019949526,0.000031446372,0.00016531844,0.00007513795,0.00001539691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011571597,0.00005672485,0.000051158888,0.000010539519,0.00005199149,0.0000053354634,0.00008462344,0.000044035656,0.0000060201137],"category_scores_gemma":[0.000093864684,0.000033171233,0.000049671893,0.00002880613,0.000034292294,0.0000012546446,0.000025135481,0.000019025054,6.3411863e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012555387,0.000011925469,0.000098803495,0.000006461011,0.000028320921,3.3752016e-8,0.000056547582,0.000057768983,0.969155,0.000056504,0.0005720537,0.029944023],"study_design_scores_gemma":[0.00024119733,0.000112638656,0.00075116905,0.0000049297055,0.000010299601,7.1552233e-7,0.00005204448,0.00023345719,0.9722423,0.000021211428,0.026273273,0.000056796704],"about_ca_topic_score_codex":0.000009854135,"about_ca_topic_score_gemma":0.000021693522,"teacher_disagreement_score":0.6937038,"about_ca_system_score_codex":0.000004618198,"about_ca_system_score_gemma":0.000015068595,"threshold_uncertainty_score":0.13526836},"labels":[],"label_agreement":null},{"id":"W2358027606","doi":"10.18192/uojm.v6i1.1564","title":"Gene Therapy and Modification as a Therapeutic Strategy for Cancer","year":2016,"lang":"en","type":"article","venue":"University of Ottawa Journal of Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Genetic enhancement; CRISPR; Oncolytic virus; Cancer; Genome editing; Immunotherapy; Virotherapy; Cancer therapy; Gene; Gene transfer; Immune system; Cas9; Gene delivery; Cancer research; Medicine; Computational biology; Biology; Immunology; Genetics","score_opus":0.02518091730469753,"score_gpt":0.3061398415783876,"score_spread":0.28095892427369007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2358027606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9096551,0.009286112,0.07856446,0.0022234363,0.000069156544,0.00007163066,0.0000053296867,0.000001232293,0.00012353472],"genre_scores_gemma":[0.99141747,0.0076828785,0.00044087932,0.000045162666,0.00012168133,7.528473e-8,0.0000011112561,0.0000036975466,0.00028705221],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973744,0.000010069434,0.00008360207,0.000056665715,0.000059131966,0.000053094234],"domain_scores_gemma":[0.9996746,0.000014188997,0.00009378336,0.00005758548,0.00011961467,0.000040199695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012285457,0.000043413736,0.00009161173,0.000036219244,0.000018723782,7.8082974e-7,0.00006982742,0.000035567366,0.000028671062],"category_scores_gemma":[0.000014648907,0.000029366547,0.00002899523,0.000018956727,0.00007460108,0.000002745246,0.0000060073485,0.000018728959,9.576287e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012103847,0.000011606851,0.0008706799,0.0000078988005,0.00007198549,0.0000011499808,0.00009225501,0.00006478584,0.90572864,0.00012699713,0.00052880653,0.09237418],"study_design_scores_gemma":[0.01084256,0.0036442836,0.03463724,0.00017128035,0.00013886867,0.00010069423,0.00090795464,0.00011275302,0.7799729,0.0005963804,0.16868784,0.00018723498],"about_ca_topic_score_codex":0.000023539504,"about_ca_topic_score_gemma":0.000010679544,"teacher_disagreement_score":0.16815902,"about_ca_system_score_codex":0.0000059617323,"about_ca_system_score_gemma":0.000036179274,"threshold_uncertainty_score":0.1197533},"labels":[],"label_agreement":null},{"id":"W2372431333","doi":"","title":"Detection of Genetically Modified Plant by Electrochemiluminescence PCR Method","year":2004,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Electrochemiluminescence; Cauliflower mosaic virus; Genetically modified organism; Chemiluminescence; Molecular biology; Biology; Chemistry; Genetically modified crops; Chromatography; Detection limit; Genetics; Gene; Transgene","score_opus":0.0054062341572429,"score_gpt":0.26959786179902917,"score_spread":0.2641916276417863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2372431333","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.33262807,0.00040519907,0.6664115,0.000021957781,0.000029208228,0.000057712256,0.0000055667806,0.000009880765,0.00043085695],"genre_scores_gemma":[0.9827178,0.000119849836,0.016867649,0.00005322117,0.00004901221,0.000008668683,0.0000347672,0.000012192363,0.00013682399],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938494,0.000008986394,0.00015065067,0.00020622295,0.00008348295,0.00016569863],"domain_scores_gemma":[0.9996931,0.0000049757014,0.000027252487,0.00018163178,0.000039218525,0.00005384941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007346078,0.00010037414,0.00009528272,0.000020681948,0.000016768945,0.0000046309115,0.0001012777,0.000097100194,0.000005412138],"category_scores_gemma":[0.000027768468,0.0000957574,0.000049647668,0.000062090316,0.00002342831,9.040995e-7,0.00003111193,0.000046522644,0.0000014699863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026488691,0.000026773647,0.000013505574,0.000011565869,0.00001638123,3.1925623e-7,0.0000106990865,0.0014561486,0.9963934,0.00006933514,0.000073148745,0.0019022382],"study_design_scores_gemma":[0.0003483919,0.00019111272,0.00010800262,0.0000041796325,0.000008857936,0.00001834324,0.000010381256,0.00044391488,0.99750304,0.000075350916,0.0011712479,0.00011716415],"about_ca_topic_score_codex":0.00003036547,"about_ca_topic_score_gemma":0.000017018781,"teacher_disagreement_score":0.65008974,"about_ca_system_score_codex":0.000008099919,"about_ca_system_score_gemma":0.000024669698,"threshold_uncertainty_score":0.39048737},"labels":[],"label_agreement":null},{"id":"W2377743252","doi":"10.1016/j.fsigen.2016.05.004","title":"DNA transfer during laundering may yield complete genetic profiles","year":2016,"lang":"en","type":"article","venue":"Forensic Science International Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Quebec Rehabilitation Research Network; McGill University; Natural Sciences and Engineering Research Council of Canada; École de Technologie Supérieure","funders":"","keywords":"Yield (engineering); Computational biology; Biology; Materials science","score_opus":0.017424408010617738,"score_gpt":0.2854325456948093,"score_spread":0.26800813768419157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2377743252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9508578,0.0001731321,0.04671703,0.00029164038,0.0008767926,0.0001320452,0.000030352376,0.000024746485,0.00089646317],"genre_scores_gemma":[0.9938546,0.00018498347,0.0046783346,0.00008546571,0.00044056663,0.000017191935,0.00000800235,0.000024029394,0.00070684764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846554,0.000008301474,0.00024140022,0.00047843443,0.00042417174,0.00038213882],"domain_scores_gemma":[0.9993171,0.000016504839,0.000030027417,0.0003349377,0.00017363418,0.00012781481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001291761,0.00017154125,0.00010099792,0.00012298957,0.00012152697,0.00005910949,0.00058101164,0.00006727899,0.00008323558],"category_scores_gemma":[0.00009747812,0.00013766024,0.00007634248,0.00014000482,0.00037016315,0.000009931019,0.0001878367,0.000050733124,0.000027648548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001631186,0.000012289858,0.0038491124,0.0000062015165,0.000019259416,0.0000035852872,0.000071334594,0.00072259986,0.98896515,0.00012588696,0.000085612395,0.0061226613],"study_design_scores_gemma":[0.00034892897,0.00008440732,0.04387665,0.000042428583,0.0000075644707,0.00006488034,0.000054835677,0.00041736214,0.9502472,0.00010906891,0.004506061,0.00024057158],"about_ca_topic_score_codex":0.000004082764,"about_ca_topic_score_gemma":0.000019735337,"teacher_disagreement_score":0.04299678,"about_ca_system_score_codex":0.000041552736,"about_ca_system_score_gemma":0.00007472844,"threshold_uncertainty_score":0.5613622},"labels":[],"label_agreement":null},{"id":"W2382589658","doi":"","title":"Apoptosis detection of tetraploid embryos and production on chimeric embryos","year":2013,"lang":"en","type":"article","venue":"Dongbei Nongye Daxue xuebao","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Science North","funders":"","keywords":"Embryo; Electrofusion; Transgene; TUNEL assay; Biology; Apoptosis; Cell biology; Green fluorescent protein; Complementation; Cell fusion; Genetically modified organism; Zygote; Chimera (genetics); Gene; Molecular biology; Genetics; Cell culture; Embryogenesis; Phenotype","score_opus":0.004728615039462303,"score_gpt":0.24005260218558463,"score_spread":0.23532398714612232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2382589658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99627835,0.0004173767,0.0016742317,0.00007525849,0.0003809284,0.00034211166,0.000006306476,0.000024789424,0.0008006267],"genre_scores_gemma":[0.9982822,0.0002261106,0.00031826296,0.00004471093,0.000269075,0.000067001514,0.000030082614,0.000029357087,0.0007331757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990541,0.000026851127,0.00020836889,0.0003725419,0.00012445677,0.00021368258],"domain_scores_gemma":[0.9994193,0.0000092336095,0.00006933267,0.00034714432,0.00007680815,0.00007822757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009154531,0.00017775803,0.00015739075,0.00009466299,0.00006672948,0.00002486985,0.00009504039,0.00012607852,0.000021147122],"category_scores_gemma":[0.00007572751,0.00017142421,0.00006503679,0.000149821,0.000059100956,0.000009436912,0.00004780653,0.00010200225,0.000020160043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028033617,0.00004947711,0.0006650458,0.00004673486,0.000039157698,1.5353561e-7,0.00004068289,0.00028334704,0.9837485,0.0000064996457,0.00034678995,0.014745612],"study_design_scores_gemma":[0.00026425542,0.00035557512,0.016310943,0.000019382596,0.000022273232,0.0000116795345,0.00007400205,0.0001798373,0.9802698,0.000021549258,0.0022770937,0.00019363024],"about_ca_topic_score_codex":0.00008797119,"about_ca_topic_score_gemma":0.000021757562,"teacher_disagreement_score":0.015645897,"about_ca_system_score_codex":0.000009630516,"about_ca_system_score_gemma":0.00001326665,"threshold_uncertainty_score":0.6990477},"labels":[],"label_agreement":null},{"id":"W2395959166","doi":"10.1007/978-1-61779-882-5_21","title":"Rolling Circle Amplification-Mediated Long Hairpin RNA Library Construction in Plants","year":2012,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Small hairpin RNA; Gene; Computational biology; Gene silencing; Biology; Genetics; RNA; RNA silencing; RNA interference; Cloning (programming); Functional genomics; Population; Complementary DNA; Genome; Computer science; Genomics","score_opus":0.01310349005698176,"score_gpt":0.37596604646952836,"score_spread":0.3628625564125466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2395959166","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4022177,0.0028628532,0.59396744,0.000051679395,0.00028466783,0.00012604243,0.000005410584,0.00001669373,0.00046749692],"genre_scores_gemma":[0.6904003,0.00033210823,0.3087398,0.0001470754,0.000105014034,0.00003324757,0.0001992398,0.000025831458,0.000017361126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985109,0.0004111514,0.00031127443,0.0003221662,0.000041692507,0.00040281587],"domain_scores_gemma":[0.99949557,0.000057080764,0.000063052226,0.0002940907,0.000008928111,0.000081289436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048511312,0.00015215142,0.00020696042,0.00018033646,0.000023138085,0.0000099758545,0.00016750414,0.0002935868,0.000018151457],"category_scores_gemma":[0.00018005609,0.00017441409,0.00005537887,0.0002026075,0.00007218343,0.000010012714,0.00009496312,0.00017204518,0.000005161856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027188686,0.000036101326,0.09983083,0.000010938569,0.000015840655,0.0000037063076,0.000040626855,0.0004397925,0.8842597,0.000251516,0.0000070085707,0.015076752],"study_design_scores_gemma":[0.000568414,0.00005362695,0.049173176,0.00001849,0.0000059240165,0.000032546563,0.000066555585,0.0005531531,0.9464993,0.00044840164,0.0023183264,0.00026208896],"about_ca_topic_score_codex":0.000009473449,"about_ca_topic_score_gemma":0.0000050010153,"teacher_disagreement_score":0.28818262,"about_ca_system_score_codex":0.00001096121,"about_ca_system_score_gemma":0.000028436272,"threshold_uncertainty_score":0.71124},"labels":[],"label_agreement":null},{"id":"W2399342261","doi":"10.1186/s12977-016-0270-0","title":"CRISPR/Cas9: a double-edged sword when used to combat HIV infection","year":2016,"lang":"en","type":"article","venue":"Retrovirology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; SWORD; Human immunodeficiency virus (HIV); Medicine; Virology; Cas9; Computational biology; Biology; Immunology; Bioinformatics; Genetics; Computer science; World Wide Web; Gene","score_opus":0.01370862665907602,"score_gpt":0.2996128818741972,"score_spread":0.2859042552151212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2399342261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9020609,0.00016153125,0.09521166,0.0013625103,0.00039837905,0.00018879765,0.000008937129,0.000044862853,0.0005624159],"genre_scores_gemma":[0.9966049,0.00006292656,0.0005134176,0.00040396533,0.00036755615,0.000041102034,0.000022318165,0.00003286934,0.0019509008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890965,0.00004532219,0.00019157845,0.00040120195,0.00008850238,0.00036373804],"domain_scores_gemma":[0.9993185,0.000020517251,0.000040225008,0.00043016663,0.000047920126,0.00014270266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013854796,0.00017641146,0.00018638019,0.00009013958,0.00005259601,0.000012472319,0.00014767764,0.00023985264,0.000106213665],"category_scores_gemma":[0.000071223905,0.0001412887,0.000088386914,0.00007332516,0.00004955675,0.0000034951654,0.000131506,0.000081038736,0.0001780282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021927003,0.000028978244,0.027333237,0.000009086717,0.000040374005,0.000003737595,0.00006217436,0.000093458846,0.96134716,0.00010531953,0.0076348693,0.003122346],"study_design_scores_gemma":[0.002738314,0.00101008,0.04284349,0.000015693882,0.000034230845,0.00005248656,0.00001010374,0.00002921327,0.68382436,0.0001187041,0.26893455,0.00038875669],"about_ca_topic_score_codex":0.00003288303,"about_ca_topic_score_gemma":0.00013684001,"teacher_disagreement_score":0.27752277,"about_ca_system_score_codex":0.000026117608,"about_ca_system_score_gemma":0.000027768587,"threshold_uncertainty_score":0.57615864},"labels":[],"label_agreement":null},{"id":"W2400411104","doi":"10.1038/nmeth.3871","title":"Comparison of Cas9 activators in multiple species","year":2016,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":553,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Activator (genetics); Cas9; Biology; Computational biology; Cooperativity; CRISPR; Gene expression; Gene; Cell biology; Regulation of gene expression; Transcription factor; Genetics","score_opus":0.0261591798199725,"score_gpt":0.4468460745435732,"score_spread":0.4206868947236007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2400411104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8358862,0.0022120306,0.16061065,0.000079530226,0.0002876405,0.00007310319,0.000007677703,0.0000065268064,0.0008366737],"genre_scores_gemma":[0.9293788,0.00004410861,0.070153296,0.000017438035,0.00008545352,0.0000034310647,0.0000035306928,0.000009504963,0.00030442787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994544,0.000069295515,0.00014018633,0.00015482327,0.000060539078,0.000120795696],"domain_scores_gemma":[0.9996314,0.00007877525,0.000036133806,0.00019782742,0.000027539261,0.000028324363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023243976,0.00008081957,0.00014578948,0.000045331082,0.000010200502,0.0000022048846,0.000101278514,0.00023049374,0.000016817437],"category_scores_gemma":[0.00044030097,0.00005671051,0.00004862722,0.00007890833,0.000032447937,0.0000012640298,0.00004754225,0.000116079675,6.330089e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024508163,0.00002107879,0.046135332,0.000009175976,0.00001008664,3.376133e-7,0.00004212187,0.00003837656,0.9279856,0.00004625735,0.0003084641,0.025378648],"study_design_scores_gemma":[0.0002797275,0.000044144508,0.045766357,0.000013761623,0.000003087971,0.0000011743203,0.000046240733,0.000036803092,0.90483695,0.000026751582,0.04886932,0.00007565023],"about_ca_topic_score_codex":0.0000042509664,"about_ca_topic_score_gemma":0.00002572235,"teacher_disagreement_score":0.09349264,"about_ca_system_score_codex":0.000008794675,"about_ca_system_score_gemma":0.000013472847,"threshold_uncertainty_score":0.23125875},"labels":[],"label_agreement":null},{"id":"W2404451320","doi":"10.1158/1538-7445.fbcr15-pr03","title":"Abstract PR03: High-resolution detection of fitness genes and genotype-specific cancer vulnerabilities with CRISPR-Cas9 screens","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Biology; CRISPR; Gene; Genetics; Gene knockout; Context (archaeology); Computational biology; RNA interference; RNA","score_opus":0.033244287744331774,"score_gpt":0.3577820944463337,"score_spread":0.32453780670200194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2404451320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9715674,0.019503802,0.008329444,0.00018674287,0.000092831564,0.00019484357,0.00006484397,0.000008930552,0.00005114188],"genre_scores_gemma":[0.98620915,0.012804425,0.00012475491,0.000004606715,0.00031567345,0.00013424044,0.000005916966,0.000023593688,0.00037765907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989821,0.000043278087,0.00013474551,0.0003163362,0.0002282139,0.00029536808],"domain_scores_gemma":[0.9992904,0.00003387873,0.000031799642,0.00025632337,0.0003128953,0.00007468752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026890181,0.000109715664,0.00011675187,0.00008354692,0.00009948467,0.000017144104,0.00010434803,0.00009702929,0.000062997824],"category_scores_gemma":[0.00002809655,0.00007620027,0.000025382797,0.0001308279,0.0002452651,0.000007266874,0.00006604418,0.00009796287,0.0000016471763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023924845,0.0000123620275,0.0012856249,0.00009464429,0.000031743213,0.0000012225744,0.000049645805,0.000500407,0.9529501,0.000029865041,0.00014451066,0.044660613],"study_design_scores_gemma":[0.00046784582,0.00019442946,0.034640532,0.000110271256,0.000005976509,0.0000035843138,0.00009033555,0.000015110086,0.95724255,0.00003307279,0.007073594,0.00012269216],"about_ca_topic_score_codex":0.00092236005,"about_ca_topic_score_gemma":0.0012643085,"teacher_disagreement_score":0.04453792,"about_ca_system_score_codex":0.000051362204,"about_ca_system_score_gemma":0.000089269975,"threshold_uncertainty_score":0.31073567},"labels":[],"label_agreement":null},{"id":"W2406226695","doi":"10.1007/978-1-62703-968-0_3","title":"PCR-Based Bioprospecting for Homing Endonucleases in Fungal Mitochondrial rRNA Genes","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Université de Montréal","funders":"","keywords":"Homing endonuclease; Bioprospecting; Mitochondrial DNA; Homing (biology); Biology; Endonuclease; Genome; Gene; Computational biology; Metagenomics; Genetics; Botany","score_opus":0.014840935072899804,"score_gpt":0.403408037158425,"score_spread":0.3885671020855252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406226695","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19760399,0.0013278421,0.80011815,0.000057582212,0.00044334028,0.00029928845,0.000007702357,0.000015545727,0.00012656311],"genre_scores_gemma":[0.25690204,0.00002545618,0.74232864,0.00020501968,0.00029646582,0.00012671882,0.0000457106,0.00004259131,0.00002733207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824345,0.00029996855,0.0003638585,0.00057687203,0.000049743172,0.00046608524],"domain_scores_gemma":[0.9993084,0.00015577149,0.000073981966,0.0003588139,0.000041073552,0.00006195675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077025,0.00023035923,0.00031371467,0.00018328523,0.000043626915,0.000016293328,0.00023498952,0.00028774558,0.000005864344],"category_scores_gemma":[0.00089636166,0.00024133862,0.00014901577,0.00016074283,0.00007217524,0.0000018350789,0.000091701535,0.00013427463,9.773962e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000936586,0.000046515008,0.005129397,0.000028802557,0.000015378359,0.0000038461394,0.000015322777,0.0025905161,0.9630345,0.00053959637,0.0000074083528,0.028495034],"study_design_scores_gemma":[0.0018785772,0.00034140085,0.00058360345,0.000019632957,0.000012758867,0.000009785912,0.00002564955,0.0064495765,0.9799832,0.0011792728,0.009214035,0.0003025086],"about_ca_topic_score_codex":0.000038760714,"about_ca_topic_score_gemma":0.00006897674,"teacher_disagreement_score":0.059298057,"about_ca_system_score_codex":0.000023434115,"about_ca_system_score_gemma":0.000033672924,"threshold_uncertainty_score":0.98415035},"labels":[],"label_agreement":null},{"id":"W2406708336","doi":"10.3727/000000004772664833","title":"Transgenic Sertoli Cells as a Vehicle for Gene Therapy","year":2004,"lang":"en","type":"review","venue":"Cell Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Genetic enhancement; Transgene; Gene; Sertoli cell; Biology; Genetically modified mouse; Immune system; Gene delivery; Function (biology); Genetically modified organism; Cell therapy; Stem cell; Immunology; Cell biology; Computational biology; Genetics; Spermatogenesis; Endocrinology","score_opus":0.01897032314261755,"score_gpt":0.3301729509654058,"score_spread":0.31120262782278824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406708336","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010046562,0.96274495,0.034732267,0.000003298064,0.00023771243,0.00092517183,0.00019172313,0.000019576471,0.00014064554],"genre_scores_gemma":[0.0012329068,0.99472016,0.0010034974,0.000023796067,0.00021025537,0.00020167013,0.0021267487,0.00008049518,0.00040046344],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99898607,0.000026976117,0.0002865603,0.00038437,0.00008220505,0.00023380008],"domain_scores_gemma":[0.99959815,0.000016891094,0.0000685906,0.00022177608,0.00002779297,0.00006681151],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006794818,0.00030237125,0.00038730682,0.0000527024,0.000051443745,0.000019519448,0.00016586315,0.00033685094,0.000014400641],"category_scores_gemma":[0.0000010877502,0.0002843723,0.00041884632,0.00006997262,0.000016544622,0.0000020064965,0.000003354769,0.00009118525,0.000022475864],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001541864,0.00014231358,6.012192e-7,0.0414098,0.00027102046,0.000011931312,0.0003737354,0.0011027753,0.3814648,0.000011320782,0.00009160913,0.5749659],"study_design_scores_gemma":[0.00081683457,0.00020487829,9.873589e-7,0.0006150911,0.00031070362,0.000022735961,0.00000501996,0.0000036556569,0.43517685,0.000011752226,0.56250626,0.00032526845],"about_ca_topic_score_codex":0.0000072005623,"about_ca_topic_score_gemma":0.0000044755075,"teacher_disagreement_score":0.57464063,"about_ca_system_score_codex":0.000016485468,"about_ca_system_score_gemma":0.00016848305,"threshold_uncertainty_score":0.99996084},"labels":[],"label_agreement":null},{"id":"W2409604727","doi":"10.1007/978-1-4939-2687-9_3","title":"Analysis of CRISPR Pre-crRNA Cleavage","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Trans-activating crRNA; CRISPR; Cleavage (geology); RNase P; Chemistry; Polyacrylamide gel electrophoresis; Biochemistry; Biology; RNA; Enzyme; Palindrome; Gene","score_opus":0.02116422241470006,"score_gpt":0.45943963107234526,"score_spread":0.4382754086576452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2409604727","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15491109,0.0020095238,0.8416747,0.00002629245,0.00014252018,0.00009939178,0.000009427966,0.000008038883,0.0011190287],"genre_scores_gemma":[0.5370006,0.00006636917,0.46255532,0.00012975263,0.000037419653,0.000018520937,0.00008237531,0.00001985753,0.000089779365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850374,0.00045198936,0.00034090583,0.0003730677,0.00006985101,0.0002604429],"domain_scores_gemma":[0.9992262,0.000032452634,0.000078450066,0.00050275563,0.000067707144,0.00009242848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010164651,0.00015622546,0.0003667278,0.0002906949,0.0000099194285,0.000004652497,0.00025322402,0.00023246504,0.000010392543],"category_scores_gemma":[0.00047093455,0.00015506678,0.00017641783,0.00055775914,0.0000903803,0.0000011526353,0.00015786996,0.000103120954,0.0000011107154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045203462,0.0000387244,0.013776648,0.000007791696,0.0003249269,0.000004411634,0.00008397674,0.006355551,0.9726215,0.0002699599,0.00006897231,0.0064023514],"study_design_scores_gemma":[0.00040949904,0.00026471907,0.005492819,0.0000035113258,0.00018633482,0.0000041549188,0.000058944068,0.0017119073,0.9850785,0.00044372384,0.0061510955,0.00019474818],"about_ca_topic_score_codex":0.00006773279,"about_ca_topic_score_gemma":0.000037015318,"teacher_disagreement_score":0.38208953,"about_ca_system_score_codex":0.000013159883,"about_ca_system_score_gemma":0.000043356802,"threshold_uncertainty_score":0.63234395},"labels":[],"label_agreement":null},{"id":"W2409736188","doi":"10.1385/1-59259-384-4:445","title":"Reverse Transcriptase In Situ PCR: New Methods in Cellular Interrogation","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"","keywords":"Reverse transcriptase; RNA; Messenger RNA; Molecular biology; Biology; In situ hybridization; In situ; Polymerase chain reaction; Nucleic acid; Reverse transcription polymerase chain reaction; Computational biology; Blot; Chemistry; Gene; Genetics","score_opus":0.04247580086175304,"score_gpt":0.3556993831683294,"score_spread":0.3132235823065763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2409736188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5511466,0.015936987,0.33738604,0.000024291661,0.0006147185,0.000723939,0.000005132883,0.000041888015,0.094120346],"genre_scores_gemma":[0.9851028,0.000077905715,0.011438534,0.000069724185,0.00005332295,0.00002007843,0.000014663194,0.00002025402,0.0032027555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992295,0.00010029251,0.00019445062,0.00023341872,0.000061932944,0.00018042183],"domain_scores_gemma":[0.99967396,0.000005486411,0.000023369885,0.00023186735,0.000010650833,0.000054638072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023018115,0.000115259645,0.000111927504,0.00006136805,0.00001441166,0.000012423898,0.000097294534,0.000099760255,0.000012401826],"category_scores_gemma":[0.000022194026,0.00012925219,0.000049902854,0.000017885584,0.000017680157,0.000002101764,0.000020335738,0.000099904355,8.872787e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019283205,0.000019110856,0.000015344136,0.000024908679,0.000009670184,0.000009615762,0.0007292815,0.00049765885,0.9870926,0.0009096884,0.0002973398,0.010375506],"study_design_scores_gemma":[0.00064429775,0.0000410513,0.000090274036,0.000020711115,0.000008642802,0.0000024195901,0.00014144095,0.00009217516,0.89077044,0.00014864969,0.10789912,0.00014075427],"about_ca_topic_score_codex":0.00009332287,"about_ca_topic_score_gemma":0.00028711342,"teacher_disagreement_score":0.43395612,"about_ca_system_score_codex":0.000015819931,"about_ca_system_score_gemma":0.00003277253,"threshold_uncertainty_score":0.5270752},"labels":[],"label_agreement":null},{"id":"W2410334038","doi":"10.1139/bcb-2015-0150","title":"Footprintless disruption of prosurvival genes in aneuploid cancer cells using CRISPR/Cas9 technology","year":2016,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Graduiertenakademie, Technische Universität Dresden; Universität Heidelberg; Deutsche Forschungsgemeinschaft","keywords":"CRISPR; Biology; Cas9; Genome editing; Genetics; Gene; Computational biology; Cancer cell; Cancer","score_opus":0.008441366269322901,"score_gpt":0.3006434426672815,"score_spread":0.2922020763979586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410334038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99106985,0.0053727143,0.0030978876,0.000057234,0.00011307097,0.00009803562,0.00003878331,0.000009872755,0.00014255852],"genre_scores_gemma":[0.9971574,0.001975136,0.0005486593,0.000010248546,0.00010756902,0.000020258249,0.000011923088,0.0000143609495,0.00015446763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990863,0.000020371344,0.00022593285,0.00038100826,0.000036671598,0.0002496782],"domain_scores_gemma":[0.99958336,0.000010698905,0.00007836139,0.0002343803,0.00004454006,0.00004867678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008814084,0.00016070879,0.0001847884,0.000057360325,0.000024896664,0.0000033659633,0.00012968443,0.00034704956,0.0000137905145],"category_scores_gemma":[0.000015702333,0.00012820012,0.0000419965,0.00009391513,0.0001888351,0.000001883851,0.00012824542,0.000058514426,6.3678266e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042929714,0.00003758319,0.020841118,0.00008521345,0.0000120571785,0.000001186531,0.000008231518,0.000037631256,0.9713466,0.000018056771,0.000005667888,0.0075637037],"study_design_scores_gemma":[0.00047747337,0.000088353845,0.0005349253,0.000032509124,0.000011058677,0.000010074297,0.00005620234,0.000029222145,0.9966563,0.000045481545,0.0018785528,0.00017986732],"about_ca_topic_score_codex":0.000027636566,"about_ca_topic_score_gemma":0.000011135413,"teacher_disagreement_score":0.025309658,"about_ca_system_score_codex":0.000014554307,"about_ca_system_score_gemma":0.000045976994,"threshold_uncertainty_score":0.52278495},"labels":[],"label_agreement":null},{"id":"W2410616080","doi":"10.1016/j.molcel.2016.03.029","title":"Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire","year":2016,"lang":"en","type":"review","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":330,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Eye Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Repertoire; Terminal (telecommunication); Genetics; Computational biology; Long terminal repeat; Evolutionary biology; Cell biology; Gene; Genome","score_opus":0.00894375105038294,"score_gpt":0.29464719800650163,"score_spread":0.2857034469561187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410616080","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011971221,0.9742591,0.012464726,0.000017219083,0.0003198799,0.0005052627,0.00015526018,0.000009798324,0.00029756493],"genre_scores_gemma":[0.03351553,0.96004045,0.0031690702,0.00017601947,0.00047787253,0.00014012818,0.00027027781,0.00017392053,0.0020367561],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981368,0.000098268516,0.000570669,0.00060824415,0.00028276298,0.00030325862],"domain_scores_gemma":[0.99865454,0.000013711693,0.00018493198,0.0009858628,0.000050192215,0.0001107504],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013948929,0.00037560877,0.00055159506,0.000065437496,0.00005636138,0.000015622747,0.00053723087,0.00029855562,0.00004474481],"category_scores_gemma":[0.000033268687,0.00027002345,0.00062929216,0.00010544958,0.00005333238,0.0000016406609,0.00013230093,0.00014824356,0.000007408784],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015639316,0.000072792,0.000059926366,0.0019725973,0.0003007735,0.000053290656,0.000026726984,0.00006802358,0.6214344,0.000018917533,0.00048663712,0.37549028],"study_design_scores_gemma":[0.00023968042,0.00007457609,0.00006561274,0.0037092655,0.00037530402,0.00002807925,0.0000039101647,0.000002594379,0.176069,0.000017765706,0.8189973,0.00041688886],"about_ca_topic_score_codex":0.000006503241,"about_ca_topic_score_gemma":0.0000031281643,"teacher_disagreement_score":0.81851065,"about_ca_system_score_codex":0.000040021678,"about_ca_system_score_gemma":0.00017190141,"threshold_uncertainty_score":0.9999752},"labels":[],"label_agreement":null},{"id":"W2411331668","doi":"10.1016/j.cbpa.2016.05.021","title":"Applications of CRISPR-Cas in its natural habitat","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Fonds de recherche du Québec – Nature et technologies; Novalait; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"CRISPR; Natural (archaeology); Biology; Computational biology; Genetics; Gene; Paleontology","score_opus":0.03831153786019007,"score_gpt":0.44647233811152626,"score_spread":0.40816080025133616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2411331668","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000055946628,0.996484,0.0016109974,0.000016588814,0.0011890846,0.00047619667,0.000111991554,0.0000067162355,0.0000484959],"genre_scores_gemma":[0.0020560734,0.9960161,0.00009660489,0.0000028988939,0.00052375824,0.00032871397,0.0009401397,0.00002376803,0.000011930537],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99845153,0.000063112304,0.00063597603,0.00050510204,0.000053720316,0.00029057593],"domain_scores_gemma":[0.99934936,0.00007340655,0.00015148129,0.0003273648,0.000043052387,0.00005535868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011697609,0.0002799923,0.00070222357,0.00016189287,0.0000077595705,0.0000030426756,0.00035435965,0.00045832465,0.000011964531],"category_scores_gemma":[0.00011965173,0.00022053663,0.0002224706,0.00020100316,0.000090733476,0.0000015188323,0.00020994627,0.0002999525,0.000018046425],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000068982595,0.00007265742,0.00009693838,0.0049677165,0.00002056467,8.7552166e-8,0.000005135583,3.6363136e-7,0.008193062,0.00019854472,0.000371094,0.98606694],"study_design_scores_gemma":[0.0002517765,0.00002727264,0.000007755061,0.0025648044,0.000011315664,0.000007339272,0.0000016526137,0.0000025535971,0.0061841756,0.000066482775,0.99062324,0.00025166094],"about_ca_topic_score_codex":0.0000010590007,"about_ca_topic_score_gemma":0.0000015714284,"teacher_disagreement_score":0.99025214,"about_ca_system_score_codex":0.000042757027,"about_ca_system_score_gemma":0.000089664645,"threshold_uncertainty_score":0.89932233},"labels":[],"label_agreement":null},{"id":"W2412186354","doi":"10.1007/978-1-59745-471-1_19","title":"Creation and Use of a Cre Recombinase Transgenic Database","year":2009,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Recombinase; Database; Computer science; Transgene; Computational biology; Biology; Genetics; Gene; Recombination","score_opus":0.05139945305885478,"score_gpt":0.4883868827947208,"score_spread":0.436987429735866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2412186354","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000109898945,0.6015964,0.39787805,0.0000041803196,0.00006121946,0.00027255533,0.000043021213,0.0000045545626,0.000030113433],"genre_scores_gemma":[0.000008439933,0.69190824,0.30746016,0.000024554545,0.000023820892,0.000033929915,0.00047083126,0.000028822022,0.000041216193],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976158,0.00093449553,0.0005685582,0.000580896,0.0000446544,0.00025558812],"domain_scores_gemma":[0.9990658,0.000100763864,0.00015935802,0.000572016,0.00003397932,0.00006804792],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061297807,0.00034446345,0.00097087264,0.00022245091,0.00001615023,0.000009765853,0.00018990213,0.0005889617,0.0000072151147],"category_scores_gemma":[0.00038370586,0.0003224199,0.00025336986,0.00019762984,0.00009885468,0.000002157529,0.00010330271,0.00022721305,5.134891e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011167531,0.000041452684,0.00000836487,0.0013755063,0.000081784776,0.000007155276,0.00000996759,0.00001193328,0.11462578,0.00015356057,0.000016249194,0.8836571],"study_design_scores_gemma":[0.00037751993,0.0003873399,0.000009456307,0.0011249778,0.00034127742,0.00006369421,0.000004799999,0.000030088722,0.04084677,0.0002031279,0.95613384,0.0004770828],"about_ca_topic_score_codex":0.000021390564,"about_ca_topic_score_gemma":0.0000102508475,"teacher_disagreement_score":0.95611763,"about_ca_system_score_codex":0.000013157501,"about_ca_system_score_gemma":0.000078926656,"threshold_uncertainty_score":0.9999228},"labels":[],"label_agreement":null},{"id":"W2412677665","doi":"10.2144/000114147","title":"Improved Injection Needles Facilitate Germline Transformation of the Buckeye Butterfly <i>Junonia Coenia</i>","year":2014,"lang":"en","type":"article","venue":"BioTechniques","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Center for Research Resources","keywords":"Transposable element; Butterfly; Germline; Transformation (genetics); Biology; Larva; Zoology; Ecology; Genetics; Genome; Gene","score_opus":0.006222289043678057,"score_gpt":0.2511974338073418,"score_spread":0.24497514476366372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2412677665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5730968,0.00017277175,0.42558387,0.0002109324,0.00013421802,0.00024007053,0.000022973009,0.000050168375,0.00048819606],"genre_scores_gemma":[0.99744964,0.000096616284,0.0020787662,0.000098900695,0.00007893586,0.000016413365,0.000023701745,0.000011033007,0.0001459774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994683,0.00003305369,0.00018690755,0.00013037513,0.00006760093,0.00011372761],"domain_scores_gemma":[0.99962354,0.000005182723,0.000053366995,0.0002502678,0.00004505662,0.000022587366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017038055,0.00010212645,0.00009068977,0.000029685078,0.000040819534,0.000009061968,0.00012744477,0.00014224518,0.000002388606],"category_scores_gemma":[0.000026461577,0.00007793132,0.000081872065,0.00007062123,0.000048072463,0.0000036002061,0.000033206743,0.00007072405,6.9108063e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018644516,0.000011135022,0.000075100266,0.00003135228,0.000007932955,1.4469632e-8,0.00011998916,0.00008143579,0.98890847,0.000033371613,0.00027713552,0.010435447],"study_design_scores_gemma":[0.00013815484,0.00022214881,0.00065202534,0.000015636037,0.000009029012,0.0000039525935,0.000027403681,0.0008767582,0.97707576,0.000057450943,0.02082702,0.00009468361],"about_ca_topic_score_codex":0.000062925996,"about_ca_topic_score_gemma":0.00002392766,"teacher_disagreement_score":0.42435285,"about_ca_system_score_codex":0.0000065918935,"about_ca_system_score_gemma":0.0000126931145,"threshold_uncertainty_score":0.31779468},"labels":[],"label_agreement":null},{"id":"W2413143420","doi":"10.1385/1-59259-434-4:227","title":"Pronuclear Microinjection of Purified Artificial Chromosomes for Generation of Transgenic Mice: Pick-and-Inject Technique","year":2004,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; D-Wave Systems (Canada)","funders":"","keywords":"Transgenesis; Insertional mutagenesis; Human artificial chromosome; Biology; Genome; Genetics; Gene; Transgene; DNA; Mutagenesis; Microinjection; Computational biology; Chromosome; Mutation; Cell biology","score_opus":0.03831782820614685,"score_gpt":0.30771239185450705,"score_spread":0.26939456364836023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413143420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91659623,0.0014172461,0.0808256,0.0000064671976,0.00008614638,0.0007257585,0.000020830863,0.0000144573705,0.0003072725],"genre_scores_gemma":[0.99645436,0.00007950569,0.0030374138,0.000006384681,0.0001766273,0.00008387549,0.000026413923,0.000019046192,0.000116388306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945563,0.000011216825,0.0002018108,0.00017748207,0.0000501901,0.00010364822],"domain_scores_gemma":[0.99972504,0.0000029922232,0.000060188453,0.00014127014,0.000049597456,0.000020894397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008102506,0.000092083676,0.00011950012,0.00003600851,0.00003740318,0.000006877615,0.000062304935,0.00010215921,0.000001056705],"category_scores_gemma":[0.000008096729,0.000097010496,0.00006954059,0.000008802307,0.000049965587,0.0000018204161,0.000017447603,0.000035813802,6.441292e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050934843,0.000022736787,9.0491955e-7,0.00013280673,0.00003268812,7.6347106e-8,0.0002328003,0.0006009884,0.9942916,0.00072179607,0.000034103192,0.0038785767],"study_design_scores_gemma":[0.0003594328,0.00034373096,0.000033486853,0.000018835943,0.00003387524,0.000004690464,0.000018387527,0.00006459281,0.9970564,0.00017770987,0.0017920823,0.0000967748],"about_ca_topic_score_codex":0.00005746043,"about_ca_topic_score_gemma":0.000053902688,"teacher_disagreement_score":0.079858124,"about_ca_system_score_codex":0.0000059391773,"about_ca_system_score_gemma":0.000028395514,"threshold_uncertainty_score":0.3955973},"labels":[],"label_agreement":null},{"id":"W2413307312","doi":"10.1101/057307","title":"Daisy-chain gene drives for the alteration of local populations","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"CRISPR; Gene drive; Population; Daisy chain; Biology; Gene; Computational biology; Computer science; Genetics","score_opus":0.013057494964479605,"score_gpt":0.26624478996267814,"score_spread":0.25318729499819853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413307312","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.28144124,0.0021415884,0.71465236,0.0001985454,0.00071979174,0.0005264609,0.00028929726,0.000028280141,0.000002394227],"genre_scores_gemma":[0.9921341,0.00021127069,0.006611609,0.000049775168,0.0007031512,0.0002126084,0.0000029548362,0.000061995546,0.000012523607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987837,0.00003239067,0.0003410189,0.0004596642,0.00013302859,0.0002502123],"domain_scores_gemma":[0.9986014,0.000026203432,0.00018236598,0.00084453664,0.00027124112,0.000074263306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025644962,0.00026264333,0.00022208104,0.00006473312,0.00015431152,0.000029962492,0.00031411738,0.00030056492,0.0000069700704],"category_scores_gemma":[0.00009407575,0.00020947399,0.00016123294,0.000072357274,0.00009791791,0.0000037242141,0.00030475575,0.00012179605,0.0000015288332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020510719,0.000029501985,0.00038258772,0.00008201193,0.00009873289,4.176252e-7,0.0000050525905,0.0034365952,0.9949519,0.00062543555,0.00035200664,0.000015218733],"study_design_scores_gemma":[0.00031647127,0.0000836304,0.010855311,0.00007410421,0.00007867399,1.2217272e-8,0.0000024794292,0.0020165893,0.98061323,0.000008523571,0.0056613754,0.00028960954],"about_ca_topic_score_codex":0.000009213111,"about_ca_topic_score_gemma":0.0000040892514,"teacher_disagreement_score":0.7106929,"about_ca_system_score_codex":0.00002845044,"about_ca_system_score_gemma":0.00015614943,"threshold_uncertainty_score":0.85421014},"labels":[],"label_agreement":null},{"id":"W2413327718","doi":"10.1093/aob/mcw089","title":"Targeted Genome Editing Using Site-Specific Nucleases, ZFNs, TALENs, and the CRISPR/Cas9 system Takashi Yamamoto (ed.).","year":2016,"lang":"en","type":"article","venue":"Annals of Botany","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SNC-Lavalin (Canada)","funders":"","keywords":"Transcription activator-like effector nuclease; Biology; CRISPR; Genome editing; Cas9; Genetics; Zinc finger nuclease; Computational biology; Gene","score_opus":0.016953907342242037,"score_gpt":0.2807785516212812,"score_spread":0.2638246442790391,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413327718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96656346,0.026765134,0.005458216,0.0003586121,0.0001949865,0.0002226545,0.000102440325,0.000023729317,0.00031078275],"genre_scores_gemma":[0.99638087,0.002205153,0.00049808127,0.0001237026,0.0005967617,0.000007585921,0.000008725008,0.000036220797,0.00014290455],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988144,0.00006587422,0.00032455192,0.00031931332,0.00015535633,0.00032052145],"domain_scores_gemma":[0.9991922,0.00003477674,0.00013518176,0.00040432936,0.00013428484,0.000099269484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036870092,0.00018947959,0.00024548254,0.000036961083,0.00010719696,0.000029135928,0.00016768734,0.00011548185,0.000028906985],"category_scores_gemma":[0.00008445428,0.0001262078,0.00012538355,0.00006637425,0.00016772562,0.000006377074,0.00013561077,0.000060446695,0.000010584995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009395948,0.000014263816,0.00037370741,0.00005656461,0.000060026927,0.000006456088,0.000052580992,0.00005926105,0.995423,0.0001551634,0.0023475152,0.0013574898],"study_design_scores_gemma":[0.0027535057,0.00028669275,0.007116939,0.0003980178,0.000089170746,0.0001571608,0.0009045721,0.0008144939,0.80488056,0.000053776585,0.18181051,0.00073462084],"about_ca_topic_score_codex":0.000023407332,"about_ca_topic_score_gemma":0.0000047620642,"teacher_disagreement_score":0.19054247,"about_ca_system_score_codex":0.000008462343,"about_ca_system_score_gemma":0.000018761099,"threshold_uncertainty_score":0.5146605},"labels":[],"label_agreement":null},{"id":"W2414695611","doi":"10.1007/978-1-4939-2727-2_15","title":"Ethics of Cancer Gene Transfer Clinical Research","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Gene transfer; Cancer; Translation (biology); Gene; Medicine; Engineering ethics; Biology; Genetics; Engineering","score_opus":0.20093644639056052,"score_gpt":0.6336943683142412,"score_spread":0.4327579219236807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414695611","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24107936,0.006339122,0.7514664,0.00024209468,0.0003314596,0.00013769302,0.000008383915,0.000005109914,0.00039038272],"genre_scores_gemma":[0.35244617,0.0014566763,0.6453113,0.00030748761,0.00021728953,0.00006340949,0.0000329196,0.000038934562,0.00012582935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962123,0.0024579554,0.0004407175,0.00041392766,0.00013217547,0.00034289583],"domain_scores_gemma":[0.9989969,0.00017360479,0.00002607042,0.00042849706,0.00025723502,0.00011765408],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007706897,0.00012622152,0.00027956103,0.00012099197,0.000019426074,0.000003948195,0.00029186966,0.00058794144,0.00001017712],"category_scores_gemma":[0.0017220126,0.00012025786,0.0001097398,0.00024091444,0.0003017813,8.6087084e-7,0.0001454069,0.0005817728,0.0000016219552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067705754,0.000051057865,0.008142672,0.000015797454,0.00004393704,0.000005154373,0.000112737274,0.00060396927,0.9778076,0.0006697125,0.00006322626,0.012416443],"study_design_scores_gemma":[0.00065676623,0.00041385615,0.0008484071,0.000011052096,0.000011030652,0.0000048713296,0.00006553302,0.00014683284,0.97465414,0.0016044473,0.021440467,0.0001425776],"about_ca_topic_score_codex":0.0001424504,"about_ca_topic_score_gemma":0.00008970297,"teacher_disagreement_score":0.11136681,"about_ca_system_score_codex":0.000015433661,"about_ca_system_score_gemma":0.0002498691,"threshold_uncertainty_score":0.4903973},"labels":[],"label_agreement":null},{"id":"W2414874570","doi":"10.1007/978-1-62703-968-0_8","title":"Rapid Screening of Endonuclease Target Site Preference Using a Modified Bacterial Two-Plasmid Selection","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Homing endonuclease; Plasmid; Endonuclease; Biology; Restriction enzyme; Genetics; Bacterial conjugation; Computational biology; DNA; Molecular biology","score_opus":0.02986903467698526,"score_gpt":0.3872431047885814,"score_spread":0.35737407011159616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414874570","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37335318,0.00019610285,0.6259819,0.0000070350634,0.00013629743,0.00010402174,0.000007210287,0.0000089460655,0.00020526937],"genre_scores_gemma":[0.46906474,0.000012807987,0.5307253,0.000041791878,0.00007725667,0.000008804708,0.000045357567,0.000018283812,0.000005640668],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980776,0.00077037315,0.0003472481,0.0004369275,0.000060406735,0.0003075026],"domain_scores_gemma":[0.9994149,0.000047819525,0.000113822185,0.00029388623,0.00006355243,0.00006597769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008554903,0.00019968563,0.00029819264,0.00013679647,0.00003420622,0.00000912284,0.00017443988,0.00022418135,0.00003001677],"category_scores_gemma":[0.00039826034,0.00021081041,0.00010176991,0.00016795262,0.00008066007,0.00000291262,0.00013236652,0.00014063252,6.8982587e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011918809,0.000026016443,0.0011146581,0.000019668296,0.000032517513,8.812245e-7,0.00002190186,0.019146545,0.9686189,0.00029544643,0.0000037458321,0.010600495],"study_design_scores_gemma":[0.0008849233,0.0002718907,0.00029702694,0.000015285665,0.000019424018,0.000015771602,0.0000079462425,0.047309753,0.94884783,0.00040735365,0.0017096567,0.00021316561],"about_ca_topic_score_codex":0.00007219334,"about_ca_topic_score_gemma":0.000012497672,"teacher_disagreement_score":0.09571156,"about_ca_system_score_codex":0.000009865992,"about_ca_system_score_gemma":0.00003353455,"threshold_uncertainty_score":0.8596599},"labels":[],"label_agreement":null},{"id":"W2415749474","doi":"10.1038/srep18676","title":"Horizontal functional gene transfer from bacteria to fishes","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ontario Museum","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Horizontal gene transfer; Gene transfer; Bacteria; Biology; Computational biology; Gene; Genetics; Phylogenetics","score_opus":0.015363210229887212,"score_gpt":0.25568489140617157,"score_spread":0.24032168117628436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2415749474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685567,0.00019914994,0.023797497,0.00007457731,0.006758729,0.000104834464,0.000013547552,0.000017922062,0.00047704056],"genre_scores_gemma":[0.9953201,0.0000012800648,0.0019523558,0.00004616369,0.00044468997,0.00001443111,0.00048880506,0.000013672073,0.0017185227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890435,0.00001103341,0.00018761703,0.00050425594,0.0002134307,0.00017932322],"domain_scores_gemma":[0.9992408,0.000002219231,0.000016087017,0.0004364928,0.00009187652,0.00021251546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027126132,0.00010241746,0.000085471635,0.00003750875,0.000059711412,0.00009054025,0.00007234032,0.000064082116,0.00008913336],"category_scores_gemma":[0.00005188325,0.000098411736,0.00005937311,0.00009464248,0.00003757148,0.000003860197,0.000051423463,0.000034120865,0.000029283554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018253835,0.000017284408,0.0014096774,0.0000012951807,0.000014432605,0.000025508505,0.00008426383,0.0003700739,0.9624678,0.000001306834,0.03491179,0.00067831716],"study_design_scores_gemma":[0.00010371677,0.000056083147,0.0048988475,0.0000030111835,0.000007621137,0.00006254495,0.000036693782,0.000015582065,0.7641674,0.00012229121,0.2303991,0.00012706427],"about_ca_topic_score_codex":0.000029448502,"about_ca_topic_score_gemma":0.00005989186,"teacher_disagreement_score":0.19830036,"about_ca_system_score_codex":0.0000129310365,"about_ca_system_score_gemma":0.000093254755,"threshold_uncertainty_score":0.40131143},"labels":[],"label_agreement":null},{"id":"W2416331553","doi":"10.1007/978-1-61779-276-2_9","title":"Pooled Lentiviral shRNA Screening for Functional Genomics in Mammalian Cells","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Small hairpin RNA; RNA interference; Computational biology; Biology; Genome; Gene; Genomics; Functional genomics; RNA; Caenorhabditis elegans; Genetics","score_opus":0.03598016671439417,"score_gpt":0.3817376164376946,"score_spread":0.3457574497233004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416331553","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13519076,0.00073452696,0.86312366,0.000020645646,0.00030590454,0.00024594218,0.000012201977,0.000007830025,0.00035855314],"genre_scores_gemma":[0.16783583,0.00003187161,0.8315695,0.00018935117,0.00008388077,0.00008210121,0.00007630965,0.000032903616,0.000098233286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859643,0.00023424691,0.00030348773,0.00044461363,0.000035935896,0.00038530928],"domain_scores_gemma":[0.99956995,0.000028397451,0.000052900472,0.00026716184,0.000031419007,0.000050195715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007663164,0.00018366057,0.00021629994,0.00014981176,0.000025261015,0.0000063372345,0.00019108664,0.0002672469,0.000022454538],"category_scores_gemma":[0.00010173695,0.00020033545,0.00012462694,0.00011216359,0.00006216086,0.000002010458,0.00012088503,0.00013160506,0.0000017407259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011577353,0.000038585786,0.0026862763,0.000011618992,0.00003188488,0.0000056975155,0.000050990537,0.0007618089,0.9818151,0.00042350675,0.000022609735,0.014036134],"study_design_scores_gemma":[0.0008902926,0.0002063318,0.003525401,0.0000065552003,0.000015645703,0.000007594409,0.000051519564,0.0007986212,0.9875903,0.0012904217,0.005369673,0.000247644],"about_ca_topic_score_codex":0.00004794215,"about_ca_topic_score_gemma":0.000053307853,"teacher_disagreement_score":0.032645088,"about_ca_system_score_codex":0.000018687615,"about_ca_system_score_gemma":0.000033433793,"threshold_uncertainty_score":0.81694424},"labels":[],"label_agreement":null},{"id":"W2416874763","doi":"10.1128/aem.01159-16","title":"Development of a CRISPR-Cas9 Tool Kit for Comprehensive Engineering of Bacillus subtilis","year":2016,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"CRISPR; Cas9; Biology; Trans-activating crRNA; Bacillus subtilis; CRISPR interference; Guide RNA; Genome editing; Genome engineering; Plasmid; Computational biology; Genetics; RNA polymerase III; Transcription (linguistics); Gene; RNA; RNA polymerase","score_opus":0.006467555077786699,"score_gpt":0.21523012203068198,"score_spread":0.20876256695289527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416874763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96855426,0.00043889886,0.030657548,0.000008558081,0.000040097537,0.0001680269,0.000109013956,0.0000042981615,0.000019298026],"genre_scores_gemma":[0.989955,0.000119674776,0.009719893,0.00001993304,0.000023430617,0.000026053907,0.00009533698,0.000013004985,0.000027651227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994294,0.000003322566,0.00020185656,0.00019644023,0.000017614984,0.0001513774],"domain_scores_gemma":[0.99978936,0.000018475448,0.00004624738,0.00011544973,0.0000044574613,0.000026038859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000036478985,0.00011595029,0.00016076774,0.000023390709,0.000018567698,9.762313e-7,0.000062019615,0.000093992916,0.000010959735],"category_scores_gemma":[0.0000034498535,0.000093168834,0.000038402646,0.000011603087,0.00008285546,0.0000010124113,0.00008971648,0.000018533497,0.0000014425704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043419815,0.000022184584,0.00020590627,0.000041477633,0.00005061158,1.00882225e-7,0.00006669549,0.000033325425,0.9918249,0.000039786057,0.00005305111,0.0076185195],"study_design_scores_gemma":[0.000671973,0.00008135969,0.0022266968,0.0000088181505,0.000010368467,0.000009368628,0.00008006428,0.000007773962,0.9591007,0.000003863051,0.037676748,0.00012222018],"about_ca_topic_score_codex":6.406798e-7,"about_ca_topic_score_gemma":9.314861e-7,"teacher_disagreement_score":0.037623696,"about_ca_system_score_codex":0.000008858578,"about_ca_system_score_gemma":0.000008100135,"threshold_uncertainty_score":0.37993148},"labels":[],"label_agreement":null},{"id":"W2418224993","doi":"10.1385/1-59745-046-4:201","title":"Retroviral Transduction of Hematopoietic Progenitors Derived From Human Embryonic Stem Cells","year":2006,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Haematopoiesis; Biology; Embryonic stem cell; Transduction (biophysics); Progenitor cell; Stem cell; Cell biology; Genetics; Gene","score_opus":0.015041883459770172,"score_gpt":0.26048800852191456,"score_spread":0.2454461250621444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2418224993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923337,0.0027089375,0.002580684,0.000002294751,0.00017958754,0.00020834435,0.000023520795,0.000028001123,0.0019349118],"genre_scores_gemma":[0.99782217,0.000021636883,0.00023566744,0.0000054388133,0.00034984414,0.000024449067,0.000049998664,0.00003083933,0.0014599457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991307,0.000029927964,0.00024782532,0.0002795593,0.00012017685,0.0001917848],"domain_scores_gemma":[0.99951863,0.0000037818857,0.00007631969,0.0003264366,0.00003677958,0.000038055186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000049412076,0.00015622975,0.00016132634,0.000030200981,0.000060968086,0.000016636257,0.00015206657,0.00012096807,0.000008217382],"category_scores_gemma":[8.166986e-7,0.00016573138,0.00011280416,0.00001040841,0.00006756583,0.000001984571,0.000039148228,0.00007065174,9.3302316e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016678754,0.000026392407,0.000041532316,0.000051788862,0.000039463364,0.0000016642875,0.00009141233,0.0003283065,0.9978242,0.00019658316,0.00024377253,0.0011382414],"study_design_scores_gemma":[0.00041034096,0.00010614322,0.000526204,0.00001766449,0.000047635996,0.0000022160352,0.000039780614,0.00002916496,0.99392766,0.00007270455,0.0046472293,0.00017328537],"about_ca_topic_score_codex":0.00027232,"about_ca_topic_score_gemma":0.00007588861,"teacher_disagreement_score":0.005488462,"about_ca_system_score_codex":0.000008653485,"about_ca_system_score_gemma":0.000013146476,"threshold_uncertainty_score":0.6758329},"labels":[],"label_agreement":null},{"id":"W2418955755","doi":"10.1038/sj.onc.1203516","title":"GA-binding protein α/β is a critical regulator of the BRCA1 promoter","year":2000,"lang":"en","type":"article","venue":"Oncogene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Cancer Care Ontario; McKnight Foundation","keywords":"Transactivation; Biology; Transcription factor; Promoter; Molecular biology; Regulator; Activator (genetics); Binding site; Transcription (linguistics); Cancer research; Cell culture; Mutant; Gene expression; Gene; Genetics","score_opus":0.0065162708232539175,"score_gpt":0.28555289913653314,"score_spread":0.27903662831327924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2418955755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963236,0.00033051454,0.0003524661,0.00040378244,0.000049257156,0.00017214927,0.000016889862,0.0000065133668,0.0023448316],"genre_scores_gemma":[0.9925082,0.000015446698,0.0012727187,0.00008739248,0.00014233314,0.00001640394,0.000004851344,0.0000172822,0.0059353933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937326,0.000019707777,0.00013960633,0.0001875759,0.00010899528,0.00017088237],"domain_scores_gemma":[0.9995606,0.0000033398069,0.00001803845,0.00034122696,0.000030369707,0.000046449928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007584551,0.00009314525,0.000088989626,0.000011555473,0.000043031116,0.000008231965,0.00015253873,0.000087989094,0.00033376474],"category_scores_gemma":[0.000032561362,0.00007145993,0.00008994398,0.00006631589,0.000059527523,0.0000013162901,0.000049145565,0.00005102837,0.000015208216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014892721,0.000027995116,0.00013368625,0.000023108601,0.000015349153,8.3280685e-7,0.000034070377,0.000021117003,0.99420565,0.000029292152,0.0004909262,0.005003103],"study_design_scores_gemma":[0.00017438972,0.000077998106,0.00036160726,0.000030463007,0.000011650471,0.000015361218,0.000010196353,0.00006363817,0.96864945,0.000029193983,0.030482132,0.00009390811],"about_ca_topic_score_codex":0.000004604638,"about_ca_topic_score_gemma":0.0000035321193,"teacher_disagreement_score":0.029991206,"about_ca_system_score_codex":0.00000510904,"about_ca_system_score_gemma":0.000033164095,"threshold_uncertainty_score":0.36544898},"labels":[],"label_agreement":null},{"id":"W2428382841","doi":"10.1385/1-59259-761-0:143","title":"Gene Targeting at the Chromosomal Immunoglobulin Locus: A Model System for the Study of Mammalian Homologous Recombination Mechanisms","year":2004,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Homologous recombination; Biology; Gene; Homologous chromosome; Gene targeting; Genetics; Plasmid; Recombination; Transfection; DNA; Locus (genetics); Genetic recombination; Molecular biology","score_opus":0.02013680937396813,"score_gpt":0.2759476171288009,"score_spread":0.2558108077548328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2428382841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88085276,0.003763554,0.113484636,0.00001791189,0.00020543036,0.001297976,0.00002328875,0.000024182407,0.0003302814],"genre_scores_gemma":[0.99829215,0.000022336279,0.0007008243,0.000013842285,0.000078392746,0.00026236495,0.000022781362,0.000026952477,0.000580345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991716,0.000033589055,0.00024450533,0.0002378186,0.00011975442,0.00019272778],"domain_scores_gemma":[0.9993809,0.000013908609,0.00008904582,0.00042023012,0.00007309164,0.000022849805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002544439,0.00013947632,0.00012707297,0.0000155537,0.00029917192,0.000025895168,0.00029841007,0.00007721363,0.0000011379699],"category_scores_gemma":[0.000014327168,0.00009482082,0.000083082996,0.000010657833,0.000046922247,0.0000014502527,0.00016977605,0.00006005653,4.6844588e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001308409,0.000117527285,0.0000019407544,0.000119547236,0.00022258496,0.0000036777005,0.0019105865,0.29231617,0.6993038,0.0021517246,0.00009972372,0.0036218448],"study_design_scores_gemma":[0.001453076,0.0004946976,0.00002920834,0.000017822513,0.00010176434,0.000016017384,0.0008210884,0.005359831,0.9909305,0.0002095273,0.00040889467,0.00015757093],"about_ca_topic_score_codex":0.00018232022,"about_ca_topic_score_gemma":0.00015687948,"teacher_disagreement_score":0.29162666,"about_ca_system_score_codex":0.000033939286,"about_ca_system_score_gemma":0.000024127216,"threshold_uncertainty_score":0.3866681},"labels":[],"label_agreement":null},{"id":"W2430331709","doi":"10.1038/nmicrobiol.2016.85","title":"Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species","year":2016,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Trans-activating crRNA; Mobile genetic elements; Horizontal gene transfer; CRISPR interference; Computational biology; Genetics; Gene; Genome; Cas9","score_opus":0.004020212289826928,"score_gpt":0.24993897274353344,"score_spread":0.2459187604537065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2430331709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98954874,0.0013652918,0.0076131076,0.00012691302,0.0006947996,0.00027999168,0.00022476556,0.000009530921,0.00013688243],"genre_scores_gemma":[0.9988113,0.0001718248,0.00014574236,0.000031999203,0.00021439562,0.000012786037,0.00019084984,0.0000146674965,0.00040640082],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999174,0.000058667043,0.0002246164,0.0002862972,0.00003475952,0.00022167963],"domain_scores_gemma":[0.99957573,0.000016830016,0.000084858206,0.00021834866,0.00007592187,0.000028289023],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109617315,0.00014690867,0.00021643858,0.00007351053,0.000019767429,0.000006525761,0.00015515414,0.00052657584,0.000027436954],"category_scores_gemma":[0.000096328455,0.00010920306,0.00005161892,0.000076358374,0.00007845999,0.0000045311795,0.00008462624,0.00013532925,0.000004569338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007563556,0.000038577487,0.002066911,0.000027452612,0.00002504456,0.0000015314572,0.000026452924,0.000010334672,0.99224806,0.000058362817,0.0051460154,0.00027560905],"study_design_scores_gemma":[0.00069978787,0.0001409122,0.003649637,0.000033022305,0.000005841639,0.000017408018,0.000037243033,0.0000012671043,0.90897876,0.000003373417,0.08629807,0.00013470218],"about_ca_topic_score_codex":0.000036107656,"about_ca_topic_score_gemma":0.000042413623,"teacher_disagreement_score":0.08326934,"about_ca_system_score_codex":0.000029921657,"about_ca_system_score_gemma":0.000027977463,"threshold_uncertainty_score":0.44531715},"labels":[],"label_agreement":null},{"id":"W2431139512","doi":"10.1385/1-59259-755-6:097","title":"Gene Targeting in &lt;I&gt;Drosophila&lt;/I&gt;","year":2004,"lang":"en","type":"article","venue":"Mobile Genetic Elements","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Genome; Gene; Genetics; Computational biology; DNA; Biology; Drosophila (subgenus); genomic DNA","score_opus":0.004863030883805819,"score_gpt":0.2574070089809454,"score_spread":0.2525439780971396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2431139512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844788,0.008236091,0.005753613,0.00004363164,0.0003281293,0.0005449637,0.000023001088,0.000029606084,0.0005621791],"genre_scores_gemma":[0.98719645,0.00091946643,0.01057171,0.00015359577,0.00037576476,0.00023351681,0.00017153457,0.00006420028,0.0003137443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978993,0.00003552276,0.0005414902,0.0006159451,0.00026291565,0.00064483105],"domain_scores_gemma":[0.9992568,0.0000061113346,0.00008780059,0.0004379808,0.000057750236,0.00015358225],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023007425,0.00030765985,0.00022879716,0.00010610927,0.0000860244,0.00003027158,0.00030424332,0.00017275802,0.0000705456],"category_scores_gemma":[0.000036188074,0.00034215645,0.00011091259,0.00019480553,0.000050033763,0.0000041274784,0.00021171245,0.000107281834,0.000055769495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017350338,0.00012031295,0.0030505469,0.00002384366,0.000037070604,0.00002118222,0.0000704702,0.031841364,0.9605915,0.000013525396,0.0006369293,0.003575902],"study_design_scores_gemma":[0.002963386,0.0006102755,0.025020873,0.000046149547,0.00003209652,0.000029396733,0.000036848654,0.00031443912,0.89426625,0.00025883,0.075691156,0.00073029555],"about_ca_topic_score_codex":0.000009866035,"about_ca_topic_score_gemma":0.0000650091,"teacher_disagreement_score":0.07505422,"about_ca_system_score_codex":0.00006387007,"about_ca_system_score_gemma":0.00008010682,"threshold_uncertainty_score":0.999903},"labels":[],"label_agreement":null},{"id":"W2437789759","doi":"10.1007/978-1-60761-652-8_23","title":"Phenotype Based Functional Gene Screening Using Retrovirus-Mediated Gene Trapping in Quasi-Haploid RAW 264.7 Cells","year":2010,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Mutagenesis; Phenotype; Biology; Gene; Retrovirus; Ploidy; Genetics; Somatic cell; Mutation","score_opus":0.022166753971024623,"score_gpt":0.37864958599659904,"score_spread":0.3564828320255744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2437789759","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35357535,0.00052918436,0.64517117,0.00003325637,0.0004518709,0.00015469866,0.000009740443,0.00001619983,0.000058551028],"genre_scores_gemma":[0.35992113,0.000026715059,0.6393219,0.00031980328,0.00016580992,0.000023656807,0.00015984934,0.00004799754,0.000013110339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975874,0.0005227993,0.00049482886,0.00071195466,0.00010973129,0.0005733327],"domain_scores_gemma":[0.99910647,0.000102121,0.00010479174,0.0005062211,0.00006695557,0.00011344831],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013275741,0.00031746126,0.0003687346,0.0003202894,0.00005787648,0.00001763276,0.000269726,0.000563021,0.000057411507],"category_scores_gemma":[0.0004223864,0.00034917914,0.00014616521,0.00040182433,0.00012638328,0.0000040474033,0.00013036498,0.00052136695,0.000002706027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009136148,0.00006632793,0.0016641795,0.000013355017,0.000032107233,0.00002562657,0.000018659373,0.0195239,0.97445554,0.000035521978,0.0000064433066,0.0040670023],"study_design_scores_gemma":[0.001074597,0.00014685967,0.001277298,0.000011251805,0.000016822112,0.00001985138,0.000017023302,0.035908557,0.95962435,0.00010628416,0.0014178327,0.00037927812],"about_ca_topic_score_codex":0.00009478201,"about_ca_topic_score_gemma":0.00009027312,"teacher_disagreement_score":0.01638466,"about_ca_system_score_codex":0.000026663798,"about_ca_system_score_gemma":0.000116106,"threshold_uncertainty_score":0.99989605},"labels":[],"label_agreement":null},{"id":"W2438420784","doi":"10.1385/1-59259-755-6:227","title":"Transformation Systems in Insects","year":2004,"lang":"en","type":"article","venue":"Mobile Genetic Elements","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Transposable element; Biology; Transformation (genetics); Vector (molecular biology); Insect; Gene; Computational biology; Genetics; Genome; Ecology","score_opus":0.0050227363811799425,"score_gpt":0.26725932513404255,"score_spread":0.2622365887528626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2438420784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98284185,0.0018441568,0.014102762,0.000010806458,0.00020429617,0.00045776126,0.0000061588466,0.000011294215,0.00052090886],"genre_scores_gemma":[0.9985011,0.00024885437,0.0007910295,0.00004289008,0.00008217432,0.00019392328,0.000053742704,0.000016625887,0.00006964564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918485,0.000014960875,0.00026012992,0.00019537659,0.00011427179,0.0002304125],"domain_scores_gemma":[0.9997064,0.0000015304281,0.00002889126,0.00019196344,0.00002049369,0.000050715407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009107646,0.000113057475,0.00008924106,0.000058380076,0.000025986312,0.000016323664,0.00010549856,0.00007290183,0.0000088544175],"category_scores_gemma":[0.000005444026,0.000120607554,0.000032977907,0.000090140435,0.000012162877,0.0000023241707,0.00002440178,0.00004689138,0.000015962196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025285683,0.00013384425,0.0074004834,0.000090452115,0.00003244938,0.000007903124,0.00042655887,0.3308957,0.64902115,0.000060187103,0.0000896093,0.011816361],"study_design_scores_gemma":[0.0072704493,0.0015274667,0.08750142,0.00014648445,0.000032703796,0.00006537084,0.00077818625,0.001716214,0.83126265,0.00019021581,0.06857618,0.0009326914],"about_ca_topic_score_codex":0.000066929264,"about_ca_topic_score_gemma":0.00006742315,"teacher_disagreement_score":0.3291795,"about_ca_system_score_codex":0.000029295767,"about_ca_system_score_gemma":0.000032605454,"threshold_uncertainty_score":0.49182332},"labels":[],"label_agreement":null},{"id":"W2460536673","doi":"10.1007/978-1-4939-2687-9_16","title":"Analysis of Nuclease Activity of Cas1 Proteins Against Complex DNA Substrates","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Nuclease; Holliday junction; DNA; RecBCD; Endonuclease; Escherichia coli; Biology; Chemistry; Gene; Biochemistry; Computational biology; Genetics; DNA repair","score_opus":0.03850996858642323,"score_gpt":0.4322244509636225,"score_spread":0.39371448237719925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2460536673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5975234,0.00031071057,0.4017095,0.00001582996,0.000032902717,0.00010559125,0.000022044136,0.0000037941347,0.00027623682],"genre_scores_gemma":[0.769575,0.000022594746,0.23025659,0.000029951327,0.0000135758255,0.000011888519,0.00006959122,0.000012285107,0.000008520087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862605,0.00046578256,0.00031439244,0.00031241056,0.00006890567,0.00021248052],"domain_scores_gemma":[0.9992194,0.000031202344,0.00013094996,0.0004319434,0.00010655912,0.00007995077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074080913,0.00015308357,0.00043630978,0.00023487442,0.000009801314,0.00000290122,0.00020516202,0.00019489224,0.000008539318],"category_scores_gemma":[0.00035333325,0.00015143512,0.00017933795,0.00048657652,0.00014802277,0.0000015547258,0.00011603122,0.00008392611,3.5039565e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006444635,0.00008392618,0.006426952,0.000020272553,0.00031719048,0.000004111263,0.000050187606,0.0048244987,0.98111755,0.000082873354,0.0000067322285,0.0070012673],"study_design_scores_gemma":[0.00038114493,0.00023006956,0.0070814015,0.0000046963137,0.00011436538,0.0000017216388,0.000048151145,0.0025973304,0.98880893,0.00012048123,0.00046498174,0.00014672942],"about_ca_topic_score_codex":0.00010900651,"about_ca_topic_score_gemma":0.00008076043,"teacher_disagreement_score":0.17205161,"about_ca_system_score_codex":0.000012519894,"about_ca_system_score_gemma":0.000058900485,"threshold_uncertainty_score":0.6175345},"labels":[],"label_agreement":null},{"id":"W2460642590","doi":"10.1007/978-1-4939-2687-9_13","title":"Procedures for Generating CRISPR Mutants with Novel Spacers Acquired from Viruses or Plasmids","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Plasmid; Computational biology; Biology; Streptococcus thermophilus; Trans-activating crRNA; Genome editing; Genetics; Bacteriophage; Bacteria; DNA; Gene; Escherichia coli","score_opus":0.04633891567250576,"score_gpt":0.44171905485625723,"score_spread":0.3953801391837515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2460642590","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23326509,0.0008782619,0.76515967,0.000051665073,0.0001960742,0.0003099321,0.000060713384,0.000019109468,0.00005948051],"genre_scores_gemma":[0.09560552,0.000025689462,0.9032492,0.0005491006,0.00018442795,0.00015986768,0.00010129621,0.000056018147,0.000068863155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984793,0.00016126221,0.00028212767,0.00059056643,0.0000770517,0.0004096603],"domain_scores_gemma":[0.99926275,0.00008161541,0.000081440005,0.0003505222,0.000100143625,0.0001235243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004949447,0.00026985942,0.00030974817,0.000085283034,0.000040570063,0.00002203067,0.000236341,0.00028552653,0.0000069748116],"category_scores_gemma":[0.0011043455,0.00021382695,0.00006809396,0.00014812658,0.00010400792,0.0000032078353,0.00011450408,0.000077265046,7.246223e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004571735,0.000043869346,0.0011656628,0.000019024827,0.00008811908,0.000007733907,0.00010381887,0.0042021526,0.99124134,0.00006744406,0.000117682954,0.002485986],"study_design_scores_gemma":[0.0018825211,0.0007596021,0.000112403955,0.000023371866,0.000033131524,0.000026288333,0.0002446366,0.0029702224,0.9856719,0.00022772898,0.007695677,0.00035251168],"about_ca_topic_score_codex":0.000060255843,"about_ca_topic_score_gemma":0.00022222145,"teacher_disagreement_score":0.13808954,"about_ca_system_score_codex":0.000025943633,"about_ca_system_score_gemma":0.00021964687,"threshold_uncertainty_score":0.871961},"labels":[],"label_agreement":null},{"id":"W2460807747","doi":"10.4081/mem.2000.765","title":"L’elaborazione di “regole” per le innovazioni biotecnologiche","year":2000,"lang":"it","type":"article","venue":"Medicina e Morale","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Humanities; Art","score_opus":0.0074100353559367164,"score_gpt":0.2701364735192669,"score_spread":0.2627264381633302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2460807747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93321574,0.030469175,0.0064666206,0.008670243,0.0009659836,0.0004676165,0.000066919805,0.000094869225,0.019582815],"genre_scores_gemma":[0.9733038,0.005062774,0.00063039945,0.0009196842,0.001004879,0.000024366349,0.00021220132,0.00006464022,0.018777251],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99776196,0.00008146975,0.00046430778,0.0007043367,0.0002918998,0.000696001],"domain_scores_gemma":[0.9987521,0.000013916892,0.0000780063,0.00081032707,0.000116192314,0.00022941886],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028018796,0.0004310219,0.0004106228,0.000094798925,0.0001912212,0.000043345917,0.00040990315,0.0005549297,0.0018844465],"category_scores_gemma":[0.00006153562,0.00040901784,0.00014482354,0.000373632,0.00033993882,0.000007796285,0.00013059103,0.00040589407,0.00039776872],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022778207,0.0005542501,0.0032587275,0.00019675618,0.0003103965,0.00013222732,0.00063197786,0.0027351396,0.7565951,0.00031321394,0.040195912,0.19484855],"study_design_scores_gemma":[0.0018385671,0.0007563982,0.006834794,0.00010583862,0.0000893505,0.00009502405,0.00050955557,0.00070058263,0.19818914,0.00005274399,0.79012924,0.0006987382],"about_ca_topic_score_codex":0.00015390455,"about_ca_topic_score_gemma":0.000021243197,"teacher_disagreement_score":0.74993336,"about_ca_system_score_codex":0.000030744905,"about_ca_system_score_gemma":0.00016982033,"threshold_uncertainty_score":0.99983615},"labels":[],"label_agreement":null},{"id":"W2464806956","doi":"10.1016/j.bbamcr.2016.06.009","title":"Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9","year":2016,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":178,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"King Saud University","keywords":"CRISPR; Genome editing; Cas9; Biology; Transcription activator-like effector nuclease; Computational biology; Zinc finger nuclease; Genome; Genetics; Gene","score_opus":0.05388268752695543,"score_gpt":0.41832548319995505,"score_spread":0.36444279567299964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2464806956","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030885514,0.9598806,0.0027766938,0.000105739186,0.0006814014,0.002739527,0.00043671357,0.00015349747,0.0023403123],"genre_scores_gemma":[0.044555314,0.9476094,0.0027633547,0.00006677995,0.0016719183,0.00031082207,0.0007101672,0.0006037853,0.0017084115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99207646,0.0011528913,0.0012708041,0.002383753,0.0012586229,0.0018574746],"domain_scores_gemma":[0.995477,0.00021254357,0.0005741822,0.0026443512,0.0005165407,0.0005753438],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0014078276,0.0012759903,0.0018295677,0.0006629095,0.00039019532,0.00027566083,0.0017148231,0.001150364,0.000024060899],"category_scores_gemma":[0.00035209203,0.0010121334,0.0010789868,0.0010829887,0.00031660954,0.00002077265,0.0015277242,0.0012720684,0.00013161206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014972886,0.000120522,3.647992e-8,0.009912886,0.00035691028,0.00022056406,0.000044505123,0.000017414695,0.9683439,0.000029039535,0.0005181754,0.020286312],"study_design_scores_gemma":[0.00066849624,0.00051838026,7.309234e-7,0.0059788506,0.0002503827,0.00013836718,0.00010893658,0.000065717366,0.5277451,0.0000052932746,0.4633093,0.0012104291],"about_ca_topic_score_codex":0.00003151413,"about_ca_topic_score_gemma":0.0000038947505,"teacher_disagreement_score":0.46279112,"about_ca_system_score_codex":0.00042752852,"about_ca_system_score_gemma":0.0013820152,"threshold_uncertainty_score":0.9999992},"labels":[],"label_agreement":null},{"id":"W2465390537","doi":"10.1007/s10529-016-2164-6","title":"Genomic integration occurs in the packaging cell via unexported lentiviral precursors","year":2016,"lang":"en","type":"article","venue":"Biotechnology Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Cancer Society Research Institute","keywords":"HEK 293 cells; Cell culture; Viral vector; Lentivirus; Embryonic stem cell; Cell; Cell biology; Transfection; Viral envelope; Virology; Biology; Virus; Chemistry; Gene; Genetics; Recombinant DNA; Viral disease","score_opus":0.004994945057675279,"score_gpt":0.2346139358842678,"score_spread":0.2296189908265925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2465390537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88337976,0.00022774337,0.10741328,0.008596081,0.00013713405,0.00014753458,0.0000037677848,0.00003137863,0.00006332537],"genre_scores_gemma":[0.99854344,0.00009253621,0.0005283625,0.00067931344,0.00006481758,0.000023153498,0.000016259663,0.000014635708,0.00003746129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922997,0.000036145924,0.0001533941,0.00027242492,0.00005896882,0.0002491284],"domain_scores_gemma":[0.99957156,0.0000110664705,0.000044846915,0.00034934407,0.000007675127,0.000015501764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014402,0.00013187295,0.000086073356,0.00010378134,0.00003362868,0.000008693803,0.0002736151,0.00020652573,0.0000046265773],"category_scores_gemma":[0.00002233225,0.000085815904,0.000051531857,0.00011344259,0.00011401349,0.0000032814978,0.000056685458,0.000120803095,0.000015206117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010224668,0.0000152726,0.0027554147,0.0000029049343,0.00000814649,0.000004819254,0.000048238206,0.00001952105,0.9847593,0.000038345308,0.00094218866,0.011395643],"study_design_scores_gemma":[0.00039605974,0.00006893586,0.009788072,0.000011322753,0.000008430222,0.000015440182,0.000093579736,0.00003869519,0.9830187,0.00003437987,0.006373011,0.00015339845],"about_ca_topic_score_codex":0.000013019583,"about_ca_topic_score_gemma":0.00004376637,"teacher_disagreement_score":0.115163706,"about_ca_system_score_codex":0.00002024409,"about_ca_system_score_gemma":0.000008586849,"threshold_uncertainty_score":0.3499471},"labels":[],"label_agreement":null},{"id":"W2465518848","doi":"10.1093/molbev/msw125","title":"Functional and Evolutionary Characterization of a Gene Transfer Agent’s Multilocus “Genome”","year":2016,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Biology; Genome; Evolutionary biology; Gene; Gene transfer; Genetics; Horizontal gene transfer; Computational biology","score_opus":0.0049567609555869,"score_gpt":0.23283988329412145,"score_spread":0.22788312233853456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2465518848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.58979785,0.0010776904,0.40886998,0.00008597804,0.000055562956,0.000061889,0.000029958677,0.0000052592836,0.000015825915],"genre_scores_gemma":[0.9987572,0.0003451202,0.0004897067,0.000036096364,0.00006605703,0.000013812478,0.00018149576,0.000009423123,0.00010109969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994087,0.00003909613,0.00013801704,0.0002422801,0.000040011375,0.00013188207],"domain_scores_gemma":[0.9997692,0.0000050854364,0.000022340711,0.000110555455,0.000046596924,0.00004620293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007221138,0.00010206369,0.000094274124,0.000052334282,0.00004499329,0.0000022465767,0.0000338408,0.00014882488,0.000012238565],"category_scores_gemma":[0.0000195496,0.00008246552,0.00003613817,0.000039882656,0.00012292093,0.0000040429445,0.000028697352,0.000027516995,0.000001892084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006956345,0.000017777846,0.0068627717,0.000010578672,0.000036175163,6.046103e-7,0.0000109916255,0.000016926379,0.9906105,0.0005750507,0.000006663667,0.0017824167],"study_design_scores_gemma":[0.00068586547,0.00021383962,0.40845183,0.000009789168,0.000023883948,0.00003450965,0.00000639303,0.00006647561,0.5887764,0.0002975043,0.0012891862,0.00014433653],"about_ca_topic_score_codex":0.000005084538,"about_ca_topic_score_gemma":0.0000018680632,"teacher_disagreement_score":0.40895933,"about_ca_system_score_codex":0.000009701923,"about_ca_system_score_gemma":0.00001841692,"threshold_uncertainty_score":0.33628464},"labels":[],"label_agreement":null},{"id":"W2466033530","doi":"10.1007/s002940100201","title":"Cis -acting sites contributing to expression of divergently transcribed DAL1 and DAL4 genes in S. cerevisiae : a word of caution when correlating cis -acting sequences with genome-wide expression analyses","year":2001,"lang":"en","type":"article","venue":"Current Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Genetics; Intergenic region; Genome; Gene; Saccharomyces cerevisiae; Transcription (linguistics); Promoter; Computational biology; Regulatory sequence; Gene expression","score_opus":0.03869785517159476,"score_gpt":0.3431305825927145,"score_spread":0.30443272742111976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2466033530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8791323,0.016818928,0.10362012,0.000015707736,0.000086888496,0.00026575715,0.000026446789,0.00001013192,0.000023747858],"genre_scores_gemma":[0.9913612,0.0023893146,0.006019033,0.0000072117887,0.00008256588,0.000014691943,0.000094163486,0.000024690951,0.000007125826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832284,0.00007748555,0.0005594747,0.0004275769,0.00022212081,0.00039049218],"domain_scores_gemma":[0.9991409,0.00006957988,0.00027295583,0.0002589976,0.0001414572,0.00011610828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000273751,0.0002494721,0.00035180617,0.00013949042,0.00010770753,0.000023498742,0.00016307064,0.000106044055,0.000012844003],"category_scores_gemma":[0.00015472007,0.0002265261,0.000073435265,0.00024173167,0.00005663654,0.000012476721,0.00017154275,0.00012581679,2.341648e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106233005,0.000034860288,0.14997827,0.00013285546,0.000019847093,0.0000018788187,0.0009881158,0.014883421,0.80997694,3.084456e-7,0.0000050235085,0.023872238],"study_design_scores_gemma":[0.0006265728,0.00022967173,0.029576682,0.00058928225,0.00005975691,0.000006095403,0.0012542922,0.0013647286,0.9652432,0.000007867225,0.0007452216,0.00029661617],"about_ca_topic_score_codex":0.000035869805,"about_ca_topic_score_gemma":0.000062481275,"teacher_disagreement_score":0.15526626,"about_ca_system_score_codex":0.000021063413,"about_ca_system_score_gemma":0.000039641724,"threshold_uncertainty_score":0.92374665},"labels":[],"label_agreement":null},{"id":"W2467860689","doi":"10.1007/978-1-62703-761-7_14","title":"A Bacterial One-Hybrid System to Isolate Homing Endonuclease Variants with Altered DNA Target Specificities","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences","keywords":"Homing endonuclease; Endonuclease; Biology; Plasmid; DNA; Restriction enzyme; Genetics; Gene; Homing (biology); Locus (genetics); Genomic library; Computational biology; genomic DNA; Base sequence","score_opus":0.011133567094511281,"score_gpt":0.33546154313673426,"score_spread":0.32432797604222297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2467860689","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30159226,0.000134854,0.69683504,0.000042658306,0.00039990759,0.00022367746,0.000018726076,0.00002452542,0.00072833087],"genre_scores_gemma":[0.46024498,0.000008343467,0.53909457,0.00016535827,0.00030061998,0.000043763055,0.000050238108,0.00004540892,0.000046696856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977326,0.0006879742,0.0003538254,0.0006440312,0.00007562517,0.00050595857],"domain_scores_gemma":[0.999104,0.000047267255,0.00007708248,0.0005696963,0.000051779487,0.00015014355],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00081795215,0.00028909702,0.0004096757,0.00015053869,0.000051255258,0.000032817425,0.00029967676,0.00016825042,0.000031013766],"category_scores_gemma":[0.00020322113,0.00027785843,0.00008455173,0.00013083722,0.00006706104,0.000002794442,0.00018585057,0.00013913758,0.000008775497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000245184,0.000028249411,0.00020361762,0.000043723594,0.00006305373,0.000015767117,0.00005438473,0.0010950222,0.9941953,0.00071628107,0.000028694367,0.0033107623],"study_design_scores_gemma":[0.0009893944,0.00072798115,0.00050037814,0.000058500766,0.000025945483,0.000078096375,0.00007545223,0.0014736303,0.97996706,0.00013538338,0.015525403,0.00044278742],"about_ca_topic_score_codex":0.00003202126,"about_ca_topic_score_gemma":0.000012922553,"teacher_disagreement_score":0.15865271,"about_ca_system_score_codex":0.000029427238,"about_ca_system_score_gemma":0.00003664931,"threshold_uncertainty_score":0.99996734},"labels":[],"label_agreement":null},{"id":"W2468401125","doi":"10.1038/srep27697","title":"Improvement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levels","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transactivation; Inducer; Gene; Gene expression; Biology; Regulation of gene expression; Transcription (linguistics); Activator (genetics); Genetics; Transcription factor; Cell biology; Computational biology","score_opus":0.014138732925883994,"score_gpt":0.26218675635223265,"score_spread":0.24804802342634866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2468401125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.920482,0.00024979096,0.07661128,0.00018119637,0.0020173127,0.00028278917,0.00004947682,0.000010405575,0.00011577065],"genre_scores_gemma":[0.99251676,0.000005705966,0.0018092371,0.000029376708,0.000049845195,0.000021108615,0.000016486758,0.000013926666,0.005537567],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986885,0.000015845684,0.00028521975,0.0005066615,0.00025945518,0.00024427747],"domain_scores_gemma":[0.9988464,0.0000060363795,0.00012366138,0.00082246226,0.00007985246,0.00012157963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003233943,0.00012775192,0.000114307026,0.000038065715,0.0001544089,0.000027352213,0.00016952191,0.00007649615,0.00009012621],"category_scores_gemma":[0.00012842753,0.00008032023,0.00009732377,0.00015095662,0.00012331414,0.000009548132,0.000076636825,0.000041394473,0.0000023402763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009345542,0.00006113272,0.00018919083,0.00000956095,0.000010480573,0.0000023543557,0.000038103677,0.0001474336,0.9911233,3.4038345e-7,0.0069093513,0.0014994121],"study_design_scores_gemma":[0.00013445942,0.00005893645,0.00024765162,0.000042127638,0.000009443575,0.000018500168,0.000032428674,0.0000021477754,0.95837075,0.000042529344,0.04091986,0.00012117728],"about_ca_topic_score_codex":0.0000075053154,"about_ca_topic_score_gemma":0.000007257117,"teacher_disagreement_score":0.07480204,"about_ca_system_score_codex":0.000030376093,"about_ca_system_score_gemma":0.00009082843,"threshold_uncertainty_score":0.32753637},"labels":[],"label_agreement":null},{"id":"W2469297379","doi":"10.1038/ncomms12144","title":"Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Azrieli Foundation; Israel Science Foundation; Rosetrees Trust; New York Stem Cell Foundation","keywords":"Biology; Genetics; RNA-Seq; Gene; Phenotype; Gene expression; Karyotype; Homologous recombination; Ploidy; Comparative genomic hybridization; Molecular biology; Genome; Chromosome; Transcriptome","score_opus":0.014711152607417434,"score_gpt":0.3257818636844852,"score_spread":0.31107071107706774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469297379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98350996,0.009656176,0.002824631,0.0026782355,0.000039627597,0.00011335289,0.00007017013,0.0000089625955,0.0010988835],"genre_scores_gemma":[0.995936,0.0026613274,0.0009399702,0.000044010936,0.000007319661,0.000016298725,0.00022090132,0.000005471568,0.00016869714],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995851,0.000042580017,0.00014569148,0.00011275401,0.000047290883,0.00006661262],"domain_scores_gemma":[0.9992445,0.000049388513,0.000044671222,0.00057877426,0.000058802074,0.000023836781],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010981932,0.00005620821,0.000089739464,0.000111728295,0.000035280682,0.000005235534,0.0002084874,0.00014370907,0.000007915285],"category_scores_gemma":[0.00013056435,0.000047412606,0.000039871175,0.00027031227,0.00005068074,0.0000035282167,0.000097119904,0.00008937615,4.78402e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000047690955,0.00008928115,0.027092757,0.000003852812,0.00018028021,6.01132e-8,0.00008481481,0.000071112765,0.9636488,0.0010699435,0.0014990268,0.0062553138],"study_design_scores_gemma":[0.0018019327,0.00021512131,0.5374178,0.00006497422,0.0004823274,0.0000049167843,0.00018244836,0.0038635326,0.34548634,0.00030472234,0.10961681,0.00055901636],"about_ca_topic_score_codex":0.000019420499,"about_ca_topic_score_gemma":0.0012393915,"teacher_disagreement_score":0.61816245,"about_ca_system_score_codex":0.000009072563,"about_ca_system_score_gemma":0.000014773895,"threshold_uncertainty_score":0.193343},"labels":[],"label_agreement":null},{"id":"W2470683212","doi":"10.1371/journal.pone.0158294","title":"Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Leibniz-Gemeinschaft; York University; Deutsches Zentrum für Infektionsforschung","keywords":"Provirus; CRISPR; Cas9; Biology; Long terminal repeat; Gene silencing; Computational biology; Virus latency; Transcription (linguistics); Guide RNA; Genetics; RNA interference; Genome; Genome editing; Trans-activating crRNA; Cell biology; Gene; Viral replication; RNA; Cell culture","score_opus":0.030040353915366656,"score_gpt":0.25470097353209264,"score_spread":0.22466061961672598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2470683212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9540188,0.0010385573,0.04421989,0.00015603536,0.00015263625,0.00017756464,0.00007846216,0.000032205116,0.0001258682],"genre_scores_gemma":[0.9957815,0.00014581434,0.0026691111,0.00003598669,0.0004448443,0.000017809309,0.000040634503,0.00003345938,0.00083084614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990553,0.000030748295,0.0001788863,0.00028149618,0.00017840421,0.00027516542],"domain_scores_gemma":[0.99953216,0.000009588486,0.00004089574,0.00023501537,0.000077501965,0.000104843915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000077391975,0.00014846081,0.00016282134,0.00003783205,0.000055125027,0.000015668522,0.000116421616,0.00013030463,0.00007281446],"category_scores_gemma":[0.000043165546,0.00012251873,0.00006615003,0.00005227293,0.0000344582,0.0000064641117,0.000030794756,0.000057091554,0.000024410045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004411087,0.00013713645,0.0011940476,0.000053768836,0.00017053902,0.0000025796753,0.000026084792,0.00006438847,0.9980006,0.0000231802,0.00021620272,0.00006731751],"study_design_scores_gemma":[0.00063321873,0.00008780056,0.0019886333,0.00013185195,0.00006878863,0.0000074453683,0.00003122061,0.0006228738,0.99483794,0.0000085152105,0.0013490332,0.0002326528],"about_ca_topic_score_codex":0.0000120150635,"about_ca_topic_score_gemma":0.0000018554571,"teacher_disagreement_score":0.041762713,"about_ca_system_score_codex":0.000027966375,"about_ca_system_score_gemma":0.000046927056,"threshold_uncertainty_score":0.49961686},"labels":[],"label_agreement":null},{"id":"W2471415527","doi":"10.1093/biolreprod/78.s1.165b","title":"Genome-wide Mapping of DNA Fragmentation in Elongating Spermatids.","year":2008,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Biology; DNA fragmentation; DNA; Fragmentation (computing); Molecular biology; DNA damage; DNA polymerase II; Chromatin; Genetics; DNA clamp; TUNEL assay; Plasmid; Polymerase chain reaction; Gene; Reverse transcriptase","score_opus":0.013527896250941642,"score_gpt":0.2743757927120413,"score_spread":0.2608478964610997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2471415527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908786,0.0019262605,0.0067750933,0.000047698773,0.00013309055,0.00009596475,0.0000020230066,0.0000049496625,0.00013634848],"genre_scores_gemma":[0.9960108,0.0005267589,0.0032267582,0.0000057724014,0.00011091692,0.000005183265,0.0000671062,0.000005707931,0.00004099753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993949,0.000028420249,0.00024030266,0.00021490769,0.00003375832,0.0000876891],"domain_scores_gemma":[0.99964935,0.000005940229,0.00009701141,0.00019317189,0.000042987143,0.000011526328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017392027,0.00006032237,0.00010819255,0.000071691495,0.00001947924,5.331302e-7,0.000048869053,0.00007145145,0.000005540919],"category_scores_gemma":[0.00012719052,0.0000642358,0.000032262873,0.00009033502,0.000067276465,0.0000024872413,0.000024435376,0.0000368534,8.390368e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010641742,0.000017212553,0.10374001,0.000022002498,0.000010753478,2.5830525e-7,0.00022898923,0.0009036241,0.89266306,0.0000043818327,0.0000116055035,0.0023874303],"study_design_scores_gemma":[0.00015827257,0.00006974005,0.28183088,0.00000724207,0.0000016794602,0.000013621774,0.00010160603,0.000023849569,0.7165667,0.000019555662,0.0011564768,0.00005037363],"about_ca_topic_score_codex":0.000023670098,"about_ca_topic_score_gemma":0.0000050595136,"teacher_disagreement_score":0.17809086,"about_ca_system_score_codex":0.000007222876,"about_ca_system_score_gemma":0.000015830736,"threshold_uncertainty_score":0.261946},"labels":[],"label_agreement":null},{"id":"W2471647919","doi":"10.1093/nar/gkw614","title":"Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preference","year":2016,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Homing endonuclease; Biology; Cleavage (geology); Nuclease; Endonuclease; Cleavage and polyadenylation specificity factor; Cleavage factor; Genetics; Homing (biology); DNA; Population; Restriction enzyme; Gene; Biochemistry; RNA","score_opus":0.07422894447290335,"score_gpt":0.3630609375221058,"score_spread":0.28883199304920243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2471647919","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939972,0.0006438487,0.0042548734,0.00051202334,0.00004073152,0.00026931887,0.000020840096,0.000010210163,0.0002509356],"genre_scores_gemma":[0.99878114,0.00059618294,0.00019722304,0.000022828379,0.000121805846,0.000053591935,0.00000807276,0.000020919771,0.00019824666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989434,0.000106555904,0.0001767237,0.00026225473,0.0002599145,0.0002511884],"domain_scores_gemma":[0.999288,0.000082472805,0.00005118368,0.00037226008,0.00011887025,0.000087213215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068996515,0.00008699256,0.00008521652,0.00006710471,0.00017940921,0.000037280264,0.00022254293,0.000073252675,0.000024241004],"category_scores_gemma":[0.000490241,0.000058242185,0.000034218723,0.00011815764,0.0002073218,0.000012119256,0.00020515565,0.00010449633,0.000010381566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002184663,0.000016730573,0.0029638861,0.000035765726,0.000019246276,6.465088e-7,0.0006358594,0.000019947685,0.92900974,0.000083908664,0.00009282584,0.06709961],"study_design_scores_gemma":[0.0005958643,0.00016932651,0.25997347,0.000091655034,0.000017544426,0.000009859939,0.0010747267,0.003282697,0.73299116,0.00027775648,0.0013242015,0.0001917469],"about_ca_topic_score_codex":0.000031625128,"about_ca_topic_score_gemma":0.000013588636,"teacher_disagreement_score":0.25700957,"about_ca_system_score_codex":0.000011177932,"about_ca_system_score_gemma":0.000031323478,"threshold_uncertainty_score":0.23750474},"labels":[],"label_agreement":null},{"id":"W2474205092","doi":"10.1101/060954","title":"A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval; Jewish General Hospital; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"KWF Kankerbestrijding; Krembil Foundation; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Homology directed repair; Homologous recombination; Genome editing; Biology; Gene; DNA; Molecular biology; Non-homologous end joining; Cell biology; Chemistry; Genetics; DNA repair; Nucleotide excision repair; Genome","score_opus":0.007510863681816284,"score_gpt":0.2462159910553705,"score_spread":0.23870512737355423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2474205092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90409267,0.0010168671,0.0921681,0.00017021887,0.0013026949,0.00064487907,0.0005048439,0.000087257446,0.000012482323],"genre_scores_gemma":[0.97213763,0.000058255286,0.025911098,0.00023761154,0.0012715943,0.00021912051,0.0000023956036,0.0001541116,0.00000817847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971423,0.00011059001,0.00065455347,0.001098502,0.00035147948,0.00064253283],"domain_scores_gemma":[0.9975164,0.00003843529,0.00028495802,0.0014154923,0.00040086033,0.00034386717],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046471547,0.0005520553,0.00055093487,0.00024591907,0.00009850795,0.000039690283,0.00065855205,0.0005687776,0.000067849985],"category_scores_gemma":[0.00034411481,0.0005798394,0.00024354557,0.00021967654,0.00011585773,0.0000034072327,0.00094472733,0.00035359705,0.000015350357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007411784,0.000086101216,0.0013081062,0.00017596013,0.00011665914,0.00001884215,0.0000037887419,0.006970617,0.9908693,0.000026807287,0.00034263727,0.00000706415],"study_design_scores_gemma":[0.0007000072,0.00028232136,0.005438055,0.0001543048,0.000075357726,4.4179753e-8,0.000001136459,0.00043471376,0.98733056,0.0000016630755,0.004928976,0.00065286015],"about_ca_topic_score_codex":0.0000097787715,"about_ca_topic_score_gemma":0.000001476352,"teacher_disagreement_score":0.06804498,"about_ca_system_score_codex":0.00008799268,"about_ca_system_score_gemma":0.0005409147,"threshold_uncertainty_score":0.9996653},"labels":[],"label_agreement":null},{"id":"W2475623366","doi":"10.1002/jsfa.7913","title":"Successful detection of foreign inserts in transgenic rice TT51‐1 (BT63) by RNA‐sequencing combined with PCR","year":2016,"lang":"en","type":"article","venue":"Journal of the Science of Food and Agriculture","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Huazhong Agricultural University; National Natural Science Foundation of China; National Science Foundation","keywords":"Biology; Terminator (solar); Gene; DNA sequencing; Genetics; Primer (cosmetics); Genome; Computational biology; Polymerase chain reaction; Oryza sativa","score_opus":0.003978428322344455,"score_gpt":0.20847283453254017,"score_spread":0.2044944062101957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2475623366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99835294,0.0005289578,0.00081909046,0.00012100403,0.00004856126,0.000052670275,0.0000036319295,6.892731e-7,0.00007243527],"genre_scores_gemma":[0.9997074,0.00013825053,0.00009542903,0.00000704768,0.00002659088,5.406958e-7,1.3940277e-7,0.0000022302684,0.000022355012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994562,0.000013591235,0.0001712315,0.00008686141,0.00017012148,0.00010194683],"domain_scores_gemma":[0.9996054,0.0000070349706,0.00015828916,0.00007479864,0.00011449527,0.000039951654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019400753,0.000066260625,0.00010752161,0.000033352935,0.0000365387,0.0000073406127,0.00019528173,0.000042568852,6.406214e-7],"category_scores_gemma":[0.00003056849,0.000026799931,0.000046099853,0.00020497516,0.00011546592,0.000015325117,0.000021660064,0.000056354835,1.8449912e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004811348,0.000014228748,0.00027567844,0.000014679882,0.000010543255,2.1577195e-7,0.000059726426,0.00014974704,0.9987936,0.000007469622,0.000022185322,0.0006038182],"study_design_scores_gemma":[0.0004849157,0.0008657407,0.005788826,0.00010461496,0.000012305274,0.000046312252,0.00023683613,0.0000057293323,0.99233013,0.000056231114,0.000016602642,0.000051766463],"about_ca_topic_score_codex":0.0000059111176,"about_ca_topic_score_gemma":0.000029386234,"teacher_disagreement_score":0.006463474,"about_ca_system_score_codex":0.0000124383905,"about_ca_system_score_gemma":0.00004659814,"threshold_uncertainty_score":0.10928694},"labels":[],"label_agreement":null},{"id":"W2479285410","doi":"10.1128/aem.02128-16","title":"Extending CRISPR-Cas9 Technology from Genome Editing to Transcriptional Engineering in the Genus Clostridium","year":2016,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centurion Biofuels (Canada); University of Waterloo","funders":"Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"CRISPR; Genome editing; Biology; Genome; Genetics; Computational biology; Cas9; Gene","score_opus":0.002988185360314819,"score_gpt":0.1948008756512281,"score_spread":0.1918126902909133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2479285410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894876,0.000977772,0.008697534,0.00042284522,0.000086983164,0.00016279543,0.00010762077,0.000010491894,0.000046391226],"genre_scores_gemma":[0.9983755,0.00019996357,0.00073888403,0.00024212433,0.00023155639,0.000048917806,0.000127028,0.000016775875,0.000019269879],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991929,0.000010883663,0.00015517542,0.00033718333,0.000027995886,0.00027588173],"domain_scores_gemma":[0.9997516,0.000018507959,0.000025182908,0.00016451397,0.0000013437856,0.000038820686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000810229,0.00015029205,0.000117030235,0.00006573073,0.000043906846,0.0000067579304,0.00015511697,0.00014955288,0.0000334825],"category_scores_gemma":[0.000007548518,0.00010874328,0.000028817753,0.000046453675,0.0000700259,0.0000020287825,0.00009426645,0.00008285432,0.000017192317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013154644,0.000016415963,0.0011010288,0.0000023650412,0.000014999846,0.0000028999054,0.00006707462,0.00009516102,0.9950455,0.00009082509,0.000051248553,0.0034993691],"study_design_scores_gemma":[0.0010530293,0.00016650526,0.023620991,0.000013944411,0.000016435493,0.00011983329,0.00044063132,0.000008915068,0.8674285,0.00006784022,0.10672314,0.00034027093],"about_ca_topic_score_codex":0.0000048608044,"about_ca_topic_score_gemma":0.0000056395156,"teacher_disagreement_score":0.12761699,"about_ca_system_score_codex":0.000020923124,"about_ca_system_score_gemma":0.0000037337538,"threshold_uncertainty_score":0.44344226},"labels":[],"label_agreement":null},{"id":"W2479542477","doi":"10.4018/ijehmc.2016070101","title":"Identifying Critical Changes in Adoption of Personalized Medicine (PM) in Healthcare Management","year":2016,"lang":"en","type":"article","venue":"International Journal of E-Health and Medical Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg","funders":"","keywords":"Personalized medicine; Health care; Set (abstract data type); Medicine; Computer science; Bioinformatics; Political science","score_opus":0.04465321042836246,"score_gpt":0.4415479374088188,"score_spread":0.39689472698045636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2479542477","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26944506,0.07663228,0.067229204,0.58485585,0.0009779922,0.00030128617,0.000021802049,0.000006415736,0.00053011696],"genre_scores_gemma":[0.94975144,0.047503565,0.0019151006,0.0007062756,0.00008320006,0.000005162165,0.000011660898,0.00000407836,0.00001955155],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9989843,0.00011207109,0.00044464204,0.000073178526,0.0002839332,0.00010191476],"domain_scores_gemma":[0.9993689,0.00009536337,0.00012215598,0.0001465751,0.00013808606,0.00012892779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086863857,0.000050507908,0.00013868579,0.00017585052,0.000018504848,0.0000028362483,0.0003305595,0.00005202883,0.000017634558],"category_scores_gemma":[0.0005397932,0.00003752131,0.000023384377,0.000058106005,0.00015349718,0.000005398485,0.000120739256,0.00011164585,2.6680067e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007685014,0.00073337596,0.06575758,0.0006739328,0.00022495515,0.000053857497,0.002743135,0.000011059062,0.028640857,0.05914502,0.0016466491,0.8396011],"study_design_scores_gemma":[0.036024425,0.005234509,0.58531845,0.030188749,0.000102471044,0.0013517144,0.014999796,0.0011191836,0.005407341,0.01953432,0.29960254,0.0011164779],"about_ca_topic_score_codex":0.000055464065,"about_ca_topic_score_gemma":0.00037612976,"teacher_disagreement_score":0.8384846,"about_ca_system_score_codex":0.000035655285,"about_ca_system_score_gemma":0.00009394067,"threshold_uncertainty_score":0.15300745},"labels":[],"label_agreement":null},{"id":"W2482074696","doi":"10.1385/0-89603-509-3:75","title":"Messenger RNA Differential Display: An Unbiased Tool to Uncover Alterations in Gene Expression Underlying Biological Processes","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Gene; Biology; Gene expression; Complement (music); Somatic cell; Genetics; Cell; Computational biology; Differential display; Cell type; Messenger RNA; Cell biology; Phenotype","score_opus":0.06414024935398603,"score_gpt":0.3241983970114032,"score_spread":0.26005814765741714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2482074696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69059205,0.0137782935,0.08346308,0.00004754405,0.0016422832,0.0046138484,0.00061968545,0.00025391046,0.20498933],"genre_scores_gemma":[0.92663795,0.0006195806,0.0015482362,0.00031017474,0.0005966519,0.00023205325,0.00090688793,0.00016211635,0.068986356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983235,0.00003595695,0.0003830216,0.0007390053,0.00018542663,0.00033311138],"domain_scores_gemma":[0.99912524,0.00001672637,0.000090818474,0.00054897764,0.000082645565,0.00013557548],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007235543,0.0004419047,0.0003348551,0.00010255465,0.00010993987,0.00008648367,0.00026197714,0.00045970024,0.00006125716],"category_scores_gemma":[0.000034057,0.00040699405,0.0000996192,0.0000098134005,0.00005238444,0.0000053035747,0.00015993069,0.00023367339,0.0000036086353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016320524,0.00007792721,0.000005076761,0.00018621102,0.00009498289,0.00003321377,0.00028645803,0.0018382241,0.9887598,0.0031998248,0.0009602206,0.0043948563],"study_design_scores_gemma":[0.001094806,0.00051788776,0.0001331947,0.00038012268,0.00008663454,0.00001462092,0.000020929027,0.00008854699,0.8119281,0.0006305483,0.18360598,0.0014986593],"about_ca_topic_score_codex":0.000016968992,"about_ca_topic_score_gemma":0.00014235421,"teacher_disagreement_score":0.23604591,"about_ca_system_score_codex":0.000027233222,"about_ca_system_score_gemma":0.000057109104,"threshold_uncertainty_score":0.9998382},"labels":[],"label_agreement":null},{"id":"W2494669249","doi":"10.1186/s12864-016-2881-1","title":"A simplified method for identifying early CRISPR-induced indels in zebrafish embryos using High Resolution Melting analysis","year":2016,"lang":"en","type":"article","venue":"BMC Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; ALS Society of Canada; Fonds de Recherche du Québec - Santé; Ministère de l'Éducation, du Loisir et du Sport Québec","keywords":"Biology; High Resolution Melt; CRISPR; Indel; Zebrafish; Computational biology; Genetics; DNA microarray; Embryo; High resolution; Gene; Polymerase chain reaction; Genotype; Single-nucleotide polymorphism; Gene expression","score_opus":0.044472697500952334,"score_gpt":0.3560120404186273,"score_spread":0.31153934291767493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2494669249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5098866,0.00007133989,0.48977056,0.000012248445,0.00007607821,0.00015238945,0.000014920601,0.000007899647,0.0000079333295],"genre_scores_gemma":[0.88562834,0.000011322568,0.113996714,0.00003335249,0.00019281846,0.000026818841,0.000026358055,0.00003423504,0.00005001861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986521,0.00006650927,0.00037075687,0.00045341437,0.00008940055,0.00036784253],"domain_scores_gemma":[0.9993256,0.00006204505,0.00011504586,0.00035195213,0.00007438315,0.00007102224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005324546,0.00017339419,0.00025087126,0.00020965806,0.00007840013,0.000041706695,0.0001750969,0.00019412514,0.0000041388294],"category_scores_gemma":[0.00017410744,0.00016404568,0.0001925268,0.00024520664,0.000012653732,0.000007704952,0.00011084454,0.00006010799,0.0000015439599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060939958,0.000012996515,0.0027265423,0.000021960155,0.00011207346,6.123271e-7,0.000096276926,0.014981305,0.9804328,0.000039921917,0.000011281894,0.0015032995],"study_design_scores_gemma":[0.0012829066,0.00007872167,0.019387778,0.000026964462,0.00025360612,0.000003887482,0.00015055019,0.027254269,0.95071185,0.00026964908,0.00020325511,0.0003765745],"about_ca_topic_score_codex":0.00022222793,"about_ca_topic_score_gemma":0.0006197002,"teacher_disagreement_score":0.37577385,"about_ca_system_score_codex":0.000081014754,"about_ca_system_score_gemma":0.000067708526,"threshold_uncertainty_score":0.66895884},"labels":[],"label_agreement":null},{"id":"W2500341763","doi":"10.15252/embr.201541476","title":"Ubiquitously expressed genes participate in cell‐specific functions via alternative promoter usage","year":2016,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"Chinese academy of sciences; Beijing; China; Biology; Developmental biology; Genetics; Molecular genetics; Developmental genetics; Gene; Political science; Regulation of gene expression","score_opus":0.013501277578445568,"score_gpt":0.2758213365332803,"score_spread":0.26232005895483473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2500341763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9499034,0.0008525267,0.047234643,0.00008492186,0.0005405811,0.0001803596,0.0000056926406,0.000019779129,0.0011780867],"genre_scores_gemma":[0.9966984,0.00015991894,0.00031471835,0.000024959982,0.00031876602,0.000079535304,0.00001625452,0.000025404177,0.0023620615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998908,0.00002837482,0.00028712986,0.00039893022,0.00011024758,0.00026733713],"domain_scores_gemma":[0.9993737,0.000008836869,0.00007840285,0.00042130766,0.00004113813,0.00007662203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001557311,0.00014155966,0.00012186834,0.000046884226,0.000033810167,0.000014889216,0.00007152811,0.00008139822,0.0000905299],"category_scores_gemma":[0.000020494215,0.00010857848,0.000062459934,0.000059411414,0.000033166205,0.000004981964,0.00007048698,0.000046233872,0.000017112998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013960886,0.000054359934,0.0054532182,0.000007971883,0.000013390972,0.00014709092,0.0000840997,0.00033808898,0.9868991,0.0000012970493,0.0014221054,0.005565328],"study_design_scores_gemma":[0.00025956667,0.00008578666,0.0039556855,0.000020154994,0.000006574833,0.000060409773,0.000018456783,0.00003437848,0.93342245,0.00013455759,0.061817072,0.0001849182],"about_ca_topic_score_codex":0.000018213335,"about_ca_topic_score_gemma":0.000027452912,"teacher_disagreement_score":0.060394965,"about_ca_system_score_codex":0.000015158422,"about_ca_system_score_gemma":0.000022718401,"threshold_uncertainty_score":0.4427702},"labels":[],"label_agreement":null},{"id":"W2508591601","doi":"10.3390/laws5030037","title":"The Discussions around Precision Genetic Engineering: Role of and Impact on Disabled People","year":2016,"lang":"en","type":"article","venue":"Laws","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Corporate governance; Stakeholder; Genetic discrimination; Intervention (counseling); Public relations; Political science; Psychology; Engineering ethics; Sociology; Genetic testing; Engineering; Business; Genetics","score_opus":0.003134371290848921,"score_gpt":0.26232047224767807,"score_spread":0.25918610095682915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2508591601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954855,0.0008348479,0.0031970425,0.00010745931,0.000051400315,0.00008952633,0.000012115859,0.000006115419,0.00021601011],"genre_scores_gemma":[0.99899817,0.0004268792,0.00018112031,0.000004589649,0.00007299766,0.000009544611,0.000002990089,0.000012906569,0.0002907971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995454,0.000010906325,0.00010197186,0.00013507262,0.000066699875,0.00013995304],"domain_scores_gemma":[0.9996039,0.000048690596,0.00002182416,0.00025533634,0.00001431159,0.00005589143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005696301,0.00009047284,0.0000777418,0.000012347155,0.00004178183,0.000011075642,0.00008858811,0.00004709062,0.000006153386],"category_scores_gemma":[0.0000599099,0.000040708757,0.000050256975,0.000034288125,0.000023366256,0.0000013803742,0.000057215035,0.000025434658,0.0000024626895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044179556,0.000017538234,0.004327379,0.0000049692985,0.000024389192,1.783664e-7,0.000031821197,0.0014800178,0.97413015,0.00019289371,0.00017175282,0.01957471],"study_design_scores_gemma":[0.00085124973,0.0007552132,0.2643974,0.00008392297,0.000030407948,0.00001755955,0.00009764452,0.002761506,0.6990097,0.0006330291,0.03104468,0.0003176627],"about_ca_topic_score_codex":0.0000068286663,"about_ca_topic_score_gemma":0.000022967572,"teacher_disagreement_score":0.27512047,"about_ca_system_score_codex":0.00000536198,"about_ca_system_score_gemma":0.0000086983455,"threshold_uncertainty_score":0.16600549},"labels":[],"label_agreement":null},{"id":"W2508844583","doi":"10.1007/978-1-4939-3801-8_19","title":"CRISPR/Cas9 Genome Editing as a Strategy to Study the Tumor Microenvironment in Transgenic Mice","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Transcription activator-like effector nuclease; Zinc finger nuclease; Cas9; Biology; Transgene; Effector; Computational biology; Genome; Genome engineering; Genetically modified organism; Genetics; Gene; Cell biology","score_opus":0.015353722663827998,"score_gpt":0.3999557227793051,"score_spread":0.38460200011547707,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2508844583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56632495,0.00081631285,0.43194908,0.00025285294,0.0001191255,0.00043608987,0.0000059142553,0.000005584911,0.00009011753],"genre_scores_gemma":[0.92721343,0.00007034222,0.07176009,0.00052950234,0.00013343792,0.00019027936,0.000006384201,0.000036714144,0.000059840415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997588,0.00082896283,0.00039361586,0.0006205448,0.00007477762,0.0004941167],"domain_scores_gemma":[0.99928993,0.00006666397,0.000050126007,0.0004950373,0.000016799137,0.00008143042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012355567,0.0002444766,0.00025449722,0.0001143895,0.000038562055,0.000011224798,0.00041931853,0.00012737623,0.000047436624],"category_scores_gemma":[0.00020736891,0.00016870283,0.00009120288,0.0001802494,0.00007321488,0.0000018186266,0.00018985286,0.00015228186,0.0000131917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044388726,0.000099258425,0.0018111677,0.0000043448867,0.00004264826,0.000023055687,0.00019125926,0.0005808728,0.98150694,0.000033724355,0.0000055596806,0.015656767],"study_design_scores_gemma":[0.0010951041,0.0010836377,0.010226228,0.000012148163,0.000021746711,0.000037018734,0.0005699998,0.000015703095,0.981078,0.0003370554,0.00521725,0.00030606944],"about_ca_topic_score_codex":0.000059163485,"about_ca_topic_score_gemma":0.00010479409,"teacher_disagreement_score":0.36088848,"about_ca_system_score_codex":0.000038822993,"about_ca_system_score_gemma":0.000030861644,"threshold_uncertainty_score":0.68795013},"labels":[],"label_agreement":null},{"id":"W2515336098","doi":"10.1016/j.nmd.2016.06.152","title":"Gene editing using CRISPR/Cas9 in neuromuscular disorders","year":2016,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"CRISPR; Genome editing; Cas9; Genetics; Duchenne muscular dystrophy; Gene; Biology; Exon skipping; Missense mutation; Exon; Mutation; Dystrophin; Nemaline myopathy; Computational biology; Alternative splicing","score_opus":0.006628819088863041,"score_gpt":0.2680610404189565,"score_spread":0.2614322213300935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515336098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9492493,0.001277477,0.047470804,0.0005699859,0.0006447659,0.00035753788,0.000013240889,0.00005353696,0.0003633047],"genre_scores_gemma":[0.99709016,0.0012744236,0.00084940554,0.0002203491,0.0002940067,0.00003355301,0.000024515613,0.00011501604,0.000098565186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976903,0.00012612501,0.0003830684,0.00081984716,0.00029050236,0.00069012505],"domain_scores_gemma":[0.9990032,0.00002663941,0.00008198929,0.0006994397,0.00003657764,0.00015215538],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021694243,0.0003815006,0.0002624768,0.00017189342,0.0001082259,0.000033762386,0.00035881845,0.00019333104,0.00003720602],"category_scores_gemma":[0.00023573384,0.00034075437,0.00027714856,0.0002747059,0.00011047081,0.000016180422,0.0002054095,0.00016531932,0.0000147557885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003146067,0.0001116574,0.022551216,0.00004238776,0.000048272505,0.000016074368,0.000056657955,0.0062518558,0.9486404,0.000029092844,0.0001868104,0.022034125],"study_design_scores_gemma":[0.011484578,0.0012619119,0.1797583,0.0003027105,0.00025880986,0.00014871,0.0005521465,0.006104509,0.5465869,0.001207292,0.24833263,0.004001521],"about_ca_topic_score_codex":0.000089876485,"about_ca_topic_score_gemma":0.00037125882,"teacher_disagreement_score":0.4020535,"about_ca_system_score_codex":0.000025927968,"about_ca_system_score_gemma":0.000049168346,"threshold_uncertainty_score":0.99990445},"labels":[],"label_agreement":null},{"id":"W2515385119","doi":"10.1007/978-1-4939-3795-0_16","title":"Quantitative Microinjection of Morpholino Antisense Oligonucleotides into Mouse Oocytes to Examine Gene Function in Meiosis-I","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Fondation Jean-Louis Lévesque","keywords":"Microinjection; Morpholino; RNA interference; Germinal vesicle; Oocyte; Biology; Conditional gene knockout; Meiosis; Cell biology; Gene; Oligonucleotide; Function (biology); Genetics; Molecular biology; RNA; Embryo; Gene knockdown","score_opus":0.01566514391253097,"score_gpt":0.40141368913158226,"score_spread":0.3857485452190513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515385119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.50528026,0.0006283741,0.49378622,0.00005052418,0.00009955259,0.00012164657,0.000005962953,0.0000059495596,0.000021551328],"genre_scores_gemma":[0.5374667,0.0001781498,0.46214485,0.000082847415,0.000025268262,0.000025575284,0.000014695243,0.000021956117,0.00003993671],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833995,0.000462468,0.0004005125,0.00046861157,0.000050286013,0.00027818762],"domain_scores_gemma":[0.99937195,0.00008161082,0.00007836383,0.00033771028,0.000072633404,0.000057762252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007180639,0.00019177525,0.000294699,0.00030717364,0.000016717348,0.0000041670532,0.00014468122,0.00020882445,0.000007845984],"category_scores_gemma":[0.0005981374,0.00016356217,0.000079871614,0.00027453256,0.00009098263,0.0000034227,0.00012677522,0.000074896,0.0000037193365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002252915,0.0000510025,0.004668046,0.000017126154,0.0000335533,0.000004933282,0.00006350134,0.0007060259,0.9833782,0.00024292487,0.000011589826,0.0105978055],"study_design_scores_gemma":[0.0006189314,0.0007693039,0.0052578337,0.000026825846,0.000011237311,0.000010721279,0.000055851015,0.00007657156,0.99189025,0.0005346091,0.0005434925,0.0002043419],"about_ca_topic_score_codex":0.00016925627,"about_ca_topic_score_gemma":0.00015538203,"teacher_disagreement_score":0.0321865,"about_ca_system_score_codex":0.000032222102,"about_ca_system_score_gemma":0.00003221642,"threshold_uncertainty_score":0.6669872},"labels":[],"label_agreement":null},{"id":"W2517855006","doi":"10.1016/j.nmd.2016.06.444","title":"Gene Therapy 2.0: CRISPR/Cas9 genome editing provides novel therapeutic avenues for neuromuscular disorders","year":2016,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation","funders":"","keywords":"CRISPR; Genome editing; Cas9; Utrophin; Duchenne muscular dystrophy; Biology; Gene duplication; Computational biology; Genetic enhancement; Gene; Dystrophin; Bioinformatics; Genetics","score_opus":0.010837534954358857,"score_gpt":0.26985341232158006,"score_spread":0.2590158773672212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2517855006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69439864,0.007173208,0.29377985,0.0019531632,0.000845978,0.0014664278,0.00010815859,0.00012584853,0.00014871961],"genre_scores_gemma":[0.9924535,0.004382724,0.0011494912,0.0006013542,0.0006285018,0.00031087958,0.00009699351,0.00018887296,0.00018765905],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976591,0.000073720126,0.00036193352,0.0009049372,0.000281103,0.00071920035],"domain_scores_gemma":[0.9988081,0.000059010155,0.000119765165,0.0007785068,0.00008218846,0.0001524414],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023373932,0.00046704544,0.00029876817,0.00010629758,0.00021987314,0.000060329716,0.0004720969,0.00019718098,0.000020573832],"category_scores_gemma":[0.00016960913,0.0003813109,0.0004816706,0.00014943554,0.00014323852,0.000017887265,0.000114935196,0.00012309186,0.000009463359],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007396941,0.0001405173,0.0012093224,0.0000491212,0.000148285,0.0000012804851,0.000075195894,0.0006695986,0.93687683,0.00003812225,0.00013775713,0.060579974],"study_design_scores_gemma":[0.0065134335,0.0017255492,0.038571466,0.00004954045,0.00014974145,0.000030133031,0.00015473491,0.0005700212,0.27264684,0.0009574119,0.67706275,0.0015683718],"about_ca_topic_score_codex":0.00001730511,"about_ca_topic_score_gemma":0.00005766836,"teacher_disagreement_score":0.676925,"about_ca_system_score_codex":0.0000168135,"about_ca_system_score_gemma":0.00005592915,"threshold_uncertainty_score":0.99986386},"labels":[],"label_agreement":null},{"id":"W2517973533","doi":"10.22004/ag.econ.235110","title":"Consumers’ Willingness-To-Pay for RNAi versus Bt Rice: Are all biotechnologies the same?","year":2016,"lang":"en","type":"preprint","venue":"AgEcon Search (University of Minnesota, USA)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Science Foundation","keywords":"RNA interference; Biotechnology; Genetically modified crops; Agriculture; Genetically modified organism; Pest control; Pesticide; Biology; Willingness to pay; Bacillus thuringiensis; Business; Valuation (finance); Agricultural science; Economics; Gene; Ecology; Transgene; Genetics; RNA","score_opus":0.03490665863191626,"score_gpt":0.3096501087728928,"score_spread":0.2747434501409765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2517973533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95207334,0.0010718795,0.03775858,0.006629764,0.0005773459,0.00083633856,0.00070131884,0.000041753676,0.0003097031],"genre_scores_gemma":[0.99177015,0.0024185884,0.002998228,0.00007726107,0.00011860758,0.000007242184,0.0001437494,0.00003585508,0.0024303054],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985174,0.00005159879,0.00015764403,0.0006222751,0.00020457969,0.00044649272],"domain_scores_gemma":[0.99850476,0.00013542242,0.00014456322,0.0008623458,0.00023065215,0.00012227715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032823283,0.0002760181,0.00033395173,0.00012981502,0.00017264514,0.00002499378,0.0010583849,0.0005417442,0.000044308785],"category_scores_gemma":[0.00015224579,0.00022979775,0.00026265075,0.00009803223,0.00025817056,0.000006078833,0.0012498167,0.00033613277,0.000027979413],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033213024,0.0003135942,0.010436098,0.0021283154,0.0034686155,0.000108454326,0.0031117832,0.003372783,0.8528894,0.0010741217,0.059036713,0.060738776],"study_design_scores_gemma":[0.005439146,0.0012730842,0.031238653,0.00045235586,0.00048025188,0.000015841955,0.012230468,0.00049529795,0.32243845,0.00045195993,0.6237161,0.0017683475],"about_ca_topic_score_codex":0.00023012985,"about_ca_topic_score_gemma":0.00054486946,"teacher_disagreement_score":0.56467944,"about_ca_system_score_codex":0.000044195058,"about_ca_system_score_gemma":0.00012904442,"threshold_uncertainty_score":0.937088},"labels":[],"label_agreement":null},{"id":"W2519270966","doi":"10.1016/j.cels.2016.08.008","title":"Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci","year":2016,"lang":"en","type":"article","venue":"Cell Systems","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"DNA damage; Biology; Phenomics; Saccharomyces cerevisiae; Computational biology; Genome; Functional genomics; Mutant; DNA; Genomics; Genetics; Context (archaeology); Cell biology; Gene","score_opus":0.038474771875930604,"score_gpt":0.2543623934573078,"score_spread":0.21588762158137723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2519270966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93413115,0.000562018,0.062825024,0.0000046022783,0.000122010424,0.000098085875,0.000032768574,0.000008862226,0.0022154984],"genre_scores_gemma":[0.99864256,0.00006788361,0.0004895469,0.000002633047,0.000065082524,0.000016763923,0.000021924141,0.000022380502,0.0006712363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992995,0.000026822205,0.00019098073,0.000230701,0.00008992501,0.00016204537],"domain_scores_gemma":[0.99945813,0.00001782398,0.00009614342,0.00030593816,0.00006534012,0.000056605844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009489918,0.00012072647,0.00021100763,0.000084848456,0.000021375434,0.000011955351,0.00011492362,0.000046455934,0.000004615269],"category_scores_gemma":[0.000009484686,0.00008667282,0.00008319196,0.00017121262,0.000036383244,0.0000044241274,0.000037186837,0.000023817276,0.0000053985245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028102026,0.000038155336,0.0011076184,0.000061497616,0.00019317037,0.0000014251715,0.00018420021,0.0044451333,0.993732,0.000032605032,0.00003800885,0.00013808574],"study_design_scores_gemma":[0.00047998907,0.0002855246,0.0009213269,0.000041449483,0.00023040263,0.0000010581862,0.0011087916,0.0006339221,0.9933071,5.9736885e-7,0.0027979838,0.0001918323],"about_ca_topic_score_codex":0.000028247003,"about_ca_topic_score_gemma":0.000024065366,"teacher_disagreement_score":0.06451142,"about_ca_system_score_codex":0.000016161308,"about_ca_system_score_gemma":0.000018053375,"threshold_uncertainty_score":0.3534415},"labels":[],"label_agreement":null},{"id":"W2520006314","doi":"10.1007/s40592-016-0062-2","title":"CRISPR as a driving force: the Model T of biotechnology","year":2016,"lang":"en","type":"article","venue":"Bioethics News","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Framing (construction); Genome editing; CLARITY; Engineering ethics; Environmental ethics; Sociology; Biology; Engineering; Genetics; Gene; Philosophy","score_opus":0.025653573509364334,"score_gpt":0.33780690883125436,"score_spread":0.31215333532189005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520006314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.55220675,0.00092181657,0.4347082,0.010473338,0.0001863282,0.00018734575,0.000015288726,0.000035231893,0.0012656722],"genre_scores_gemma":[0.99589604,0.0010901152,0.0015143217,0.0002596534,0.00008097253,0.000010450815,0.0000026493706,0.00001804294,0.0011277238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993178,0.000020296688,0.00016635288,0.00020958729,0.00009692565,0.00018898772],"domain_scores_gemma":[0.99934715,0.00003123681,0.000053839372,0.00048278892,0.00004820738,0.000036759837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017597622,0.00010787549,0.00009972527,0.000033961987,0.000047346482,0.0000060885586,0.00027172102,0.0003075154,0.000008442404],"category_scores_gemma":[0.00023919392,0.000063192965,0.00007837942,0.00006199876,0.0002808752,0.0000015474819,0.00015788017,0.00010414697,0.000008965908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009886052,0.000009214444,0.00019101881,0.000007812465,0.000018483066,2.6787828e-7,0.000043571414,0.00029964265,0.987871,0.0056191944,0.0005778566,0.005352049],"study_design_scores_gemma":[0.00020804527,0.00011407798,0.000050524948,0.000018231594,0.000011034498,0.0000067666174,0.00010059156,0.0007778024,0.9876758,0.0017175112,0.009209036,0.00011057658],"about_ca_topic_score_codex":0.000039301034,"about_ca_topic_score_gemma":0.00012649226,"teacher_disagreement_score":0.44368932,"about_ca_system_score_codex":0.0000060793445,"about_ca_system_score_gemma":0.000068056725,"threshold_uncertainty_score":0.25769344},"labels":[],"label_agreement":null},{"id":"W2520728971","doi":"10.1128/jb.00389-16","title":"Spontaneous Reversions of an Evolutionary Trait Loss Reveal Regulators of a Small RNA That Controls Multicellular Development in Myxobacteria","year":2016,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; National Institutes of Health; Studienstiftung des Deutschen Volkes","keywords":"Biology; Myxococcus xanthus; Myxobacteria; Genetics; Mutant; Reversion; Gene; Response regulator; Mutation; Pregnane X receptor; Transcription factor; Regulator gene; Regulation of gene expression; Phenotype; Bacteria","score_opus":0.008520673210829013,"score_gpt":0.23991745199502976,"score_spread":0.23139677878420073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520728971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973527,0.00036948145,0.0018768649,0.000073737036,0.0001973451,0.000091682894,0.00002007724,0.0000016774849,0.000016439666],"genre_scores_gemma":[0.9910015,0.00009640012,0.0086985575,0.000017354092,0.00008756015,0.0000019172498,0.00001109658,0.000012490405,0.00007314084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998862,0.00010625592,0.00061039056,0.00014896029,0.00008427766,0.000188071],"domain_scores_gemma":[0.9991783,0.00004314493,0.0003740365,0.0001861999,0.0001284642,0.000089852285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003239487,0.0001282839,0.00037093463,0.000120687575,0.000015354693,0.00000201707,0.00020303627,0.00017219549,0.000031637843],"category_scores_gemma":[0.000101245,0.00009613007,0.00010955751,0.00004342934,0.00009463963,0.000007217829,0.000052907148,0.00007775487,5.073216e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006412889,0.000090457346,0.0040612174,0.00002602811,0.00007518134,0.00011982858,0.00009958012,0.000100735095,0.9918886,0.0000072594007,0.000017832488,0.0028720177],"study_design_scores_gemma":[0.0023338099,0.0010106378,0.3210696,0.00019310751,0.000034538258,0.0020378255,0.00007802297,0.000019215253,0.67009014,0.000038287075,0.0029125332,0.0001822537],"about_ca_topic_score_codex":0.000008345776,"about_ca_topic_score_gemma":0.000026544807,"teacher_disagreement_score":0.3217984,"about_ca_system_score_codex":0.000037553655,"about_ca_system_score_gemma":0.00014884726,"threshold_uncertainty_score":0.39200705},"labels":[],"label_agreement":null},{"id":"W2525334519","doi":"","title":"Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may infl uence risk of breast cancer","year":2013,"lang":"en","type":"article","venue":"Kölner Universitäts PublikationsServer (Universität zu Köln)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Molecular Biology Laboratory; University of Pennsylvania; University of Alberta; Brigham and Women's Hospital","keywords":"Medicine; Breast cancer; Polarization (electrochemistry); Cancer research; Cancer; Internal medicine; Chemistry","score_opus":0.0032963231116091363,"score_gpt":0.2305918418147658,"score_spread":0.22729551870315667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2525334519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99206465,0.00034963692,0.005781449,0.0008747241,0.000077885416,0.00022813736,0.00023537177,0.000026350168,0.00036180214],"genre_scores_gemma":[0.996666,0.0002603828,0.0011002772,0.000035692043,0.00008369659,0.0000022823176,0.00014169593,0.000019755065,0.0016901807],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99899244,0.00006378441,0.0001698297,0.00038837554,0.00014359037,0.0002419613],"domain_scores_gemma":[0.9991584,0.000030160798,0.00014765993,0.0002693363,0.00022729415,0.00016713826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010938132,0.00020241766,0.00019301704,0.00024825326,0.00020736468,0.000064622436,0.00022370944,0.0001866245,0.0001559952],"category_scores_gemma":[0.000022278833,0.00022514892,0.0000649098,0.0002991052,0.00017941331,0.00028000234,0.0002851174,0.00012926217,0.0000046274276],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010141061,0.00007392419,0.7680708,0.00012122123,0.0007369415,0.00000458877,0.0010691383,0.00092853117,0.2058987,0.0030757745,0.0012411397,0.018677788],"study_design_scores_gemma":[0.0012344543,0.00011355327,0.97960097,0.0000483422,0.00023940724,0.000015986416,0.0012111807,0.0008571798,0.013615242,0.0002607427,0.0024124451,0.00039051255],"about_ca_topic_score_codex":0.001364162,"about_ca_topic_score_gemma":0.00019275128,"teacher_disagreement_score":0.21153012,"about_ca_system_score_codex":0.00003677983,"about_ca_system_score_gemma":0.00006907876,"threshold_uncertainty_score":0.9181307},"labels":[],"label_agreement":null},{"id":"W2525640728","doi":"10.1101/078162","title":"A Pif1-dependent threshold separates DNA double-strand breaks and telomeres","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Krembil Foundation","keywords":"Telomere; Telomerase; DNA; Point mutation; Biology; Molecular biology; Cell biology; Genetics; Mutation; Gene","score_opus":0.009320707836975323,"score_gpt":0.2520088651480406,"score_spread":0.24268815731106527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2525640728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98687685,0.008028147,0.0032103118,0.00014475817,0.0007074084,0.0005594464,0.00026312663,0.00012022743,0.00008972438],"genre_scores_gemma":[0.99668044,0.001527769,0.0006079068,0.00008861498,0.0007716774,0.0001385831,0.0000014215418,0.0001314876,0.00005207825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99756914,0.00003475483,0.00041622322,0.0011403228,0.00025816436,0.00058141607],"domain_scores_gemma":[0.99820954,0.000015902724,0.00016855894,0.0010996371,0.00019526138,0.0003111211],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029611468,0.00062215334,0.00046405033,0.00013395962,0.00011671023,0.00018089058,0.0004240968,0.0006898042,0.000026034268],"category_scores_gemma":[0.00003317116,0.00057591056,0.00014555517,0.00009770131,0.00014155245,0.000008835733,0.00065316976,0.00035330126,0.0000198054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010303964,0.000047214926,0.0037794295,0.0002225335,0.00021379808,0.0000210925,0.000005270296,0.00009302066,0.9949502,0.000114609335,0.000444336,0.000005499304],"study_design_scores_gemma":[0.0012680996,0.00008895344,0.014052976,0.00020422431,0.0000970211,1.7993399e-7,0.0000023656703,0.000048817074,0.97546464,0.0000046974537,0.007930891,0.0008371042],"about_ca_topic_score_codex":0.000017079687,"about_ca_topic_score_gemma":0.000007669361,"teacher_disagreement_score":0.019485485,"about_ca_system_score_codex":0.000040039893,"about_ca_system_score_gemma":0.00021792915,"threshold_uncertainty_score":0.99966925},"labels":[],"label_agreement":null},{"id":"W2526459078","doi":"10.1139/bcb-2016-0137","title":"Precision genome editing in the CRISPR era","year":2016,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Genome editing; CRISPR; Cas9; Biology; Homology directed repair; Computational biology; Gene; Enhancer; Genome; Genome engineering; Genetics; DNA repair; Nucleotide excision repair; Gene expression","score_opus":0.011232213104376327,"score_gpt":0.32200060049681845,"score_spread":0.3107683873924421,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2526459078","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009216395,0.99577016,0.0003384149,0.000025915408,0.0001754447,0.00024647076,0.000082917504,0.000007975798,0.0024310548],"genre_scores_gemma":[0.0053273663,0.9923114,0.000091921196,0.00004989497,0.0011426883,0.000077626704,0.0004488999,0.000028450211,0.00052171294],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984986,0.00010764226,0.00038304398,0.00060199434,0.000059906033,0.0003487761],"domain_scores_gemma":[0.99923116,0.00007152583,0.00013103984,0.0004826352,0.000021006605,0.00006262474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033079297,0.00036065438,0.00049799104,0.000042876225,0.0000617147,0.000022136412,0.00041175092,0.0007154583,0.000025051058],"category_scores_gemma":[0.00006958564,0.00022059702,0.00018509051,0.000083371095,0.000102545855,0.0000012511626,0.00019646433,0.00026832632,0.000012426766],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000112315975,0.000048017817,0.000013745911,0.0034767324,0.00004966196,0.000010154242,0.00002955173,8.098535e-7,0.13872336,0.000014245261,0.00080117764,0.8568213],"study_design_scores_gemma":[0.00016454728,0.00006934404,0.0000040188274,0.00050792436,0.000047854865,0.000059411206,0.00002741618,5.7235684e-7,0.013545862,0.00001508208,0.98527354,0.00028441823],"about_ca_topic_score_codex":0.0000025115785,"about_ca_topic_score_gemma":0.0000011886298,"teacher_disagreement_score":0.9844724,"about_ca_system_score_codex":0.000014325008,"about_ca_system_score_gemma":0.00007700602,"threshold_uncertainty_score":0.89956856},"labels":[],"label_agreement":null},{"id":"W2527847483","doi":"10.1787/5jlsvvxn1zjc-en","title":"Adverse Outcome Pathway on Alkylation of DNA in Male Pre-Meiotic Germ Cells Leading to Heritable Mutations","year":2016,"lang":"en","type":"paratext","venue":"OECD series on adverse outcome pathways","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Health Canada","funders":"","keywords":"Meiosis; Genetics; Biology; Germ; Germline; Adverse Outcome Pathway; Germ cell; Alkylation; Cell biology; Gene; Computational biology; Biochemistry","score_opus":0.01754271309100722,"score_gpt":0.2978753135767306,"score_spread":0.28033260048572334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527847483","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8811455,0.00034892862,0.0046096025,0.0002528925,0.0051106736,0.002305407,0.002770164,0.00007966561,0.10337721],"genre_scores_gemma":[0.8179171,0.00014248402,0.0010483257,0.00027902084,0.00032951258,0.00013654075,0.0007142244,0.00016454505,0.17926824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688,0.00009396019,0.0010454498,0.00090167345,0.0003884686,0.0006904764],"domain_scores_gemma":[0.99826014,0.00007257817,0.0003604777,0.0009756647,0.00010193497,0.00022919654],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027660234,0.00069353,0.0008398775,0.0004172509,0.000105310515,0.000020764282,0.0004157289,0.0005938372,0.0008982698],"category_scores_gemma":[0.00011522387,0.0006654707,0.00036072207,0.00018769692,0.00008725008,0.000021523176,0.00018654474,0.00034005867,0.0028022255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005485371,0.00027712242,0.0024666928,0.0007917766,0.00014026738,0.000052989315,0.0005368365,0.073086664,0.91440016,0.00027365066,0.0062454934,0.0011798197],"study_design_scores_gemma":[0.0019818149,0.0014517205,0.0031002548,0.0005552939,0.00006898087,0.000018944134,0.00049640913,0.00006427464,0.7637419,0.000019404064,0.22695908,0.0015418896],"about_ca_topic_score_codex":0.000029881054,"about_ca_topic_score_gemma":0.00013260651,"teacher_disagreement_score":0.22071359,"about_ca_system_score_codex":0.00017921753,"about_ca_system_score_gemma":0.00015074431,"threshold_uncertainty_score":0.99957967},"labels":[],"label_agreement":null},{"id":"W2529324599","doi":"10.1038/ncomms12853","title":"Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Marsden Fund; Royal Society Te Apārangi; Royal Society; University of Toronto; University of Otago","keywords":"CRISPR; Biology; Plasmid; DNA; Computational biology; Genetics; Cas9; Acquired immune system; Trans-activating crRNA; Nucleic acid; Gene; Immune system","score_opus":0.011511003671865222,"score_gpt":0.319327210018697,"score_spread":0.3078162063468318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2529324599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9249676,0.010537735,0.058704555,0.0030927965,0.00022272913,0.00062925153,0.00010380889,0.000034797864,0.0017067251],"genre_scores_gemma":[0.9965279,0.00089644245,0.0022508572,0.000095191375,0.00003488517,0.00005100656,0.000040478946,0.000011616395,0.000091613416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994212,0.00006532442,0.00014086827,0.00018615823,0.000064930304,0.0001215372],"domain_scores_gemma":[0.9992053,0.000049436516,0.000054835917,0.0005533352,0.000097142045,0.000039960596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097053606,0.00010084098,0.00009645818,0.00006892206,0.000060035687,0.000013679415,0.00019920082,0.00020406689,0.000005549928],"category_scores_gemma":[0.000063089574,0.00007891391,0.000031663913,0.00008536646,0.00006333244,0.000007636497,0.00019665986,0.0001574093,0.0000030603444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001080126,0.00008359014,0.008497693,0.000043024145,0.00008469989,0.0000016826277,0.0027123874,0.000037244205,0.9768008,0.004054503,0.0016941212,0.0058822436],"study_design_scores_gemma":[0.0033736806,0.00036194397,0.17316853,0.000830171,0.00008601761,0.000047967067,0.0032176042,0.0092525175,0.7829333,0.00021202,0.025756076,0.0007601753],"about_ca_topic_score_codex":0.000024748882,"about_ca_topic_score_gemma":0.00046129126,"teacher_disagreement_score":0.1938675,"about_ca_system_score_codex":0.000054796492,"about_ca_system_score_gemma":0.00003209999,"threshold_uncertainty_score":0.32180157},"labels":[],"label_agreement":null},{"id":"W2530925810","doi":"10.1097/qad.0000000000001294","title":"New research on using CRISPR/Cas9 to treat HIV","year":2016,"lang":"en","type":"article","venue":"AIDS","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"McGill University","keywords":"CRISPR; Cas9; Genome editing; Human immunodeficiency virus (HIV); Biology; Guide RNA; Gene; Computational biology; Virology; Genetics","score_opus":0.05213808736370194,"score_gpt":0.4249809158468933,"score_spread":0.37284282848319134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2530925810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.883171,0.00022099912,0.11262127,0.0005019688,0.000121313926,0.00010332926,0.0000070242195,0.000013060452,0.0032400368],"genre_scores_gemma":[0.9848662,0.00003569746,0.0044721537,0.0001220943,0.00047679606,0.00000471368,0.0000032554776,0.00002179416,0.009997317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923915,0.000026974823,0.00008104238,0.00025185882,0.00013234904,0.0002686255],"domain_scores_gemma":[0.99945426,0.000019859111,0.000006896928,0.00033015342,0.000043458676,0.00014538183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014731742,0.00008688624,0.000069896974,0.0000740292,0.000045885237,0.000013960095,0.00013098471,0.000072957635,0.000069441776],"category_scores_gemma":[0.00007621861,0.000063153195,0.000040178,0.000108874876,0.000016094162,0.0000013227649,0.00008722457,0.00004569876,0.00013655669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034764245,0.000009278383,0.00062853296,0.0000034518348,0.000006997232,0.0000026774367,0.000020486577,0.0001507872,0.9553116,0.00012787971,0.017927108,0.025776463],"study_design_scores_gemma":[0.00030274945,0.00042108246,0.0006775364,0.000025741352,0.0000044261915,0.000005493713,0.000026141504,0.0000103004895,0.9208157,0.00005650561,0.0775418,0.00011253171],"about_ca_topic_score_codex":0.00003214806,"about_ca_topic_score_gemma":0.0000044684652,"teacher_disagreement_score":0.10814911,"about_ca_system_score_codex":0.000020412432,"about_ca_system_score_gemma":0.00004193468,"threshold_uncertainty_score":0.25753126},"labels":[],"label_agreement":null},{"id":"W2531773509","doi":"10.1093/nar/gkw914","title":"Altered stoichiometry<i>Escherichia coli</i>Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation","year":2016,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Skolkovo Institute of Science and Technology; National Institute of General Medical Sciences; Russian Science Foundation; Ministry of Education and Science of the Russian Federation; Russian Foundation for Basic Research; M.J. Murdock Charitable Trust; U.S. Department of Energy","keywords":"Trans-activating crRNA; CRISPR; Biology; Effector; CRISPR interference; RNA; Escherichia coli; RNA interference; Genetics; Random hexamer; Cell biology; Cas9; Molecular biology; Gene","score_opus":0.03488729887169334,"score_gpt":0.33478716992951707,"score_spread":0.29989987105782373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531773509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96356744,0.0006345912,0.034820303,0.0002228233,0.00003769344,0.000245264,0.000024578661,0.000012922911,0.0004344087],"genre_scores_gemma":[0.9951364,0.00039092117,0.0038597605,0.000022184699,0.00007193985,0.000022863174,0.0000103185375,0.000030898744,0.0004547346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986542,0.000092104696,0.00018082694,0.00036324767,0.00031320925,0.00039642322],"domain_scores_gemma":[0.9991511,0.00004991275,0.000055522898,0.0003434235,0.0002525602,0.00014746835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036009672,0.00014502481,0.00019291023,0.00014895074,0.00008130942,0.000026871645,0.00021419945,0.00010941005,0.000029965746],"category_scores_gemma":[0.00014570012,0.000104029605,0.000032330267,0.00026398126,0.00029393268,0.0000075780886,0.00015311567,0.0001380857,0.0000035030198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026415533,0.000033397027,0.0034783354,0.000055066015,0.000057778445,0.0000019020108,0.0001864675,0.000053416214,0.9870547,0.000031904274,0.00043018197,0.008352685],"study_design_scores_gemma":[0.00094095786,0.00083715544,0.03010686,0.00012205635,0.0000127326775,0.000006904433,0.00094095606,0.0005803591,0.9629283,0.00003403522,0.0033000787,0.00018963283],"about_ca_topic_score_codex":0.00008927253,"about_ca_topic_score_gemma":0.00018151879,"teacher_disagreement_score":0.031568967,"about_ca_system_score_codex":0.000027018996,"about_ca_system_score_gemma":0.00008379607,"threshold_uncertainty_score":0.4242204},"labels":[],"label_agreement":null},{"id":"W2531915249","doi":"10.1038/ncomms13134","title":"The solution structure of an anti-CRISPR protein","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Computational biology; Biology; DNA; ENCODE; Trans-activating crRNA; Gene; Pseudomonas aeruginosa; Genetics; Cas9; Bacteria","score_opus":0.006904017346852162,"score_gpt":0.3118007315586675,"score_spread":0.30489671421181536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531915249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97969174,0.009678622,0.0067621195,0.0030149762,0.00012399637,0.00027186814,0.000063853055,0.00001878455,0.00037406618],"genre_scores_gemma":[0.99600405,0.00041415304,0.0033346908,0.000026592726,0.000050372044,0.000007885367,0.000039717565,0.000008518452,0.000114001],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99960726,0.00004870383,0.000101484846,0.00009135583,0.000059702732,0.000091464266],"domain_scores_gemma":[0.998579,0.000019211477,0.000042105523,0.001244527,0.00008955129,0.000025579997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000074831194,0.00005860446,0.00004725148,0.000013854372,0.00013706075,0.000007525512,0.0005626265,0.00015221989,0.0000025340632],"category_scores_gemma":[0.000105078616,0.00003437668,0.000031698026,0.000053990032,0.00009970943,0.000002761906,0.00014834681,0.00012735694,7.8050925e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000047828153,0.000012850624,0.0001828369,0.0000019091203,0.0000114307395,2.1356929e-8,0.000010304079,0.0000060311745,0.99210936,0.0011954493,0.00036234758,0.0061026844],"study_design_scores_gemma":[0.00014996693,0.000046902955,0.006686392,0.00001152561,0.00000677577,0.0000032116657,0.000019442257,0.000057864007,0.9120574,0.00020182312,0.080689,0.000069719164],"about_ca_topic_score_codex":0.000004141634,"about_ca_topic_score_gemma":0.00028814116,"teacher_disagreement_score":0.08032665,"about_ca_system_score_codex":0.0000051696866,"about_ca_system_score_gemma":0.00002476761,"threshold_uncertainty_score":0.14018403},"labels":[],"label_agreement":null},{"id":"W2536296768","doi":"10.1182/blood.v124.21.244.244","title":"An Unexpected Role for Ribonuclease Inhibitor (RNH1) in Erythropoiesis","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"GATA1; Biology; Erythropoiesis; GATA2; Haematopoiesis; Cell biology; Transcription factor; Molecular biology; Gene expression; Diamond–Blackfan anemia; Gene; Stem cell; Genetics; RNA; Internal medicine","score_opus":0.003383844506995744,"score_gpt":0.25771241482414026,"score_spread":0.2543285703171445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2536296768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937283,0.00032711995,0.0053934916,0.00003765636,0.00006990274,0.00013185719,0.000011742235,0.000019336738,0.00028063467],"genre_scores_gemma":[0.9967786,0.000014366208,0.0026080066,0.00006290206,0.00035457188,0.00003382973,0.00007029748,0.000023758,0.000053669417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994109,0.00001796461,0.00011786237,0.00022534747,0.000046174086,0.00018169446],"domain_scores_gemma":[0.9996285,0.0000075379467,0.00001899629,0.00024911764,0.000028244882,0.00006764016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008181476,0.00009599465,0.000092214235,0.000034656696,0.000029271743,0.000013747373,0.00009528498,0.00008887089,0.0000071510876],"category_scores_gemma":[0.00006512879,0.00010098901,0.00004591649,0.00005226308,0.000017839418,0.0000019596343,0.00002462132,0.000034248744,0.0000030591123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025284739,0.00019451267,0.0026363155,0.0000140500315,0.000014028332,6.5357335e-7,0.00005003293,0.0002221418,0.9948374,0.000045224733,0.00016774931,0.0017926237],"study_design_scores_gemma":[0.0020288196,0.00044855435,0.008254984,0.000009615394,0.000025235784,0.0000060622183,0.000110796056,0.0011402315,0.9718822,0.00008992876,0.015790496,0.00021303026],"about_ca_topic_score_codex":0.000018349076,"about_ca_topic_score_gemma":0.00007576449,"teacher_disagreement_score":0.022955138,"about_ca_system_score_codex":0.0000030484582,"about_ca_system_score_gemma":0.000013483867,"threshold_uncertainty_score":0.41182125},"labels":[],"label_agreement":null},{"id":"W2539923080","doi":"10.1016/b978-0-12-803309-8.00012-4","title":"Genetic Engineering of Plants Using Zn Fingers, TALENs, and CRISPRs","year":2016,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Transcription activator-like effector nuclease; CRISPR; Biology; Genetics; Genome editing; Gene","score_opus":0.008558685918490334,"score_gpt":0.24638338371623222,"score_spread":0.2378246977977419,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2539923080","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13699163,0.06325655,0.004523001,0.000026535925,0.0014056995,0.001221408,0.0005393858,0.00008387063,0.7919519],"genre_scores_gemma":[0.2223752,0.003776952,0.007635808,0.000093414754,0.0014378398,0.000019682031,0.000050182494,0.00037903123,0.7642319],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989011,0.0000063453795,0.00032130114,0.00038818078,0.00013476115,0.0002482845],"domain_scores_gemma":[0.99934214,0.000013555856,0.0001206318,0.00038267384,0.000038961618,0.00010202575],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007107408,0.00034298524,0.00034252947,0.000094015726,0.00003040844,0.000011052292,0.00014146739,0.00033486946,0.000019191148],"category_scores_gemma":[0.000013330755,0.00032532535,0.00012368259,0.0000041869807,0.000073045616,0.0000012269925,0.00015239092,0.00012442883,0.0000032587882],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025760564,0.00000465102,0.00006261688,0.00035927474,0.00025880616,0.000022113603,0.000058740166,0.00018438416,0.42495105,0.0001303613,0.00006571262,0.57387656],"study_design_scores_gemma":[0.0006918402,0.00020867953,0.0002492331,0.0012170178,0.00020063214,0.00019275259,0.000007999409,0.00021312591,0.09168931,0.00022944402,0.9039814,0.0011185498],"about_ca_topic_score_codex":4.1661056e-7,"about_ca_topic_score_gemma":0.0000027043768,"teacher_disagreement_score":0.9039157,"about_ca_system_score_codex":0.000014266212,"about_ca_system_score_gemma":0.00004622638,"threshold_uncertainty_score":0.9999199},"labels":[],"label_agreement":null},{"id":"W2544218357","doi":"10.1139/bcb-2016-0159","title":"The discovery and development of the CRISPR system in applications in genome manipulation","year":2016,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"CRISPR; Cas9; Genome editing; Biology; Computational biology; Biomedicine; Function (biology); Genome engineering; Epigenome; Genetics; Gene; DNA methylation","score_opus":0.0117949447878492,"score_gpt":0.29479207306709526,"score_spread":0.28299712827924606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2544218357","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01094153,0.98783463,0.0006520371,0.0000041001563,0.000037071088,0.0003027274,0.00002554341,0.000002061204,0.0002003132],"genre_scores_gemma":[0.122483216,0.876974,0.000052737727,0.000001985867,0.000059590024,0.00012207357,0.00009873349,0.00001096264,0.00019668497],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991783,0.00003904511,0.00033983492,0.00027212713,0.000028081111,0.00014263586],"domain_scores_gemma":[0.9995547,0.000034098233,0.00012175376,0.00025705376,0.000010624609,0.000021788146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014705422,0.00016360517,0.0002617273,0.00002036247,0.000057086414,0.000008906499,0.00016693524,0.00026985852,4.245175e-7],"category_scores_gemma":[0.000009589216,0.000088384644,0.000048164577,0.000055606622,0.0000911039,9.945023e-7,0.00016505402,0.000081672275,3.5824092e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021606735,0.00006239624,0.0011851521,0.016839512,0.00009866486,8.6518304e-7,0.000086592394,0.0000065485733,0.3662241,0.00028991295,0.00001536952,0.6151693],"study_design_scores_gemma":[0.0001685106,0.000012610118,0.00033022047,0.00072418025,0.000024558276,0.000009508539,0.00010943643,0.000001595553,0.052499216,0.000006431501,0.94591033,0.00020342178],"about_ca_topic_score_codex":0.0000027801602,"about_ca_topic_score_gemma":0.000011143294,"teacher_disagreement_score":0.94589496,"about_ca_system_score_codex":0.000024153584,"about_ca_system_score_gemma":0.0000937772,"threshold_uncertainty_score":0.3604221},"labels":[],"label_agreement":null},{"id":"W2549217376","doi":"10.5376/bt.2014.05.0002","title":"Development of Insect-resistant Transgenic Rice with &lt;i&gt;cry1Ac1&lt;/i&gt; Gene","year":2014,"lang":"en","type":"article","venue":"Bt Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genetically modified rice; Transgene; Insect; Biology; Gene; Genetics; Genetically modified crops; Botany","score_opus":0.02636464674113471,"score_gpt":0.32245359540716373,"score_spread":0.29608894866602903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2549217376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9719179,0.0014024425,0.023076031,0.000048620586,0.00003681594,0.00021636517,0.000007037883,0.000012221392,0.003282524],"genre_scores_gemma":[0.9880268,0.00014378507,0.010321145,0.000013433064,0.00011605606,0.00004581033,0.0000391985,0.00003356762,0.0012602183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983044,0.00009390406,0.00025625253,0.00037039618,0.0004949551,0.00048008666],"domain_scores_gemma":[0.9991044,0.000036358473,0.000031991418,0.00045534663,0.00022565619,0.00014623808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091683026,0.00015410616,0.000173113,0.00011744466,0.000120412835,0.000019254545,0.00031950866,0.000120624885,0.000029604662],"category_scores_gemma":[0.00007386219,0.00013217567,0.000056470897,0.00023061984,0.000094566356,0.0000023484977,0.000106689185,0.00013746141,0.0000169345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016655662,0.000060194514,0.00006887395,0.00009267857,0.000060535473,0.0000020147363,0.00020897495,0.00014101423,0.9950611,0.00017308671,0.00036957354,0.0035954188],"study_design_scores_gemma":[0.00055297546,0.00032915673,0.0072973464,0.000023161288,0.000007610724,0.000005429418,0.000023875558,0.00006920118,0.83239,0.0000119432925,0.15912218,0.00016709739],"about_ca_topic_score_codex":0.000007973883,"about_ca_topic_score_gemma":0.00028600197,"teacher_disagreement_score":0.16267106,"about_ca_system_score_codex":0.000027571668,"about_ca_system_score_gemma":0.000270206,"threshold_uncertainty_score":0.5389967},"labels":[],"label_agreement":null},{"id":"W2550662841","doi":"10.1007/s00299-016-2069-9","title":"Targeted mutagenesis by CRISPR/Cas9 system in the model legume Medicago truncatula","year":2016,"lang":"en","type":"article","venue":"Plant Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Medicago truncatula; Biology; CRISPR; Mutagenesis; Cas9; Genetics; Genome editing; Medicago; Computational biology; Legume; Biotechnology; Mutation; Gene; Botany; Symbiosis; Bacteria","score_opus":0.005030861752425792,"score_gpt":0.22839871497302117,"score_spread":0.22336785322059538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2550662841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9444392,0.0031847376,0.04814184,0.00022944239,0.00040022563,0.0003349881,0.00011108937,0.00004367183,0.0031148314],"genre_scores_gemma":[0.99822104,0.00017738683,0.00024077849,0.00008977719,0.00009533391,0.00004121765,0.00014726364,0.000022175887,0.00096502085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875176,0.000037863458,0.00033285184,0.000365903,0.00022272364,0.00028887772],"domain_scores_gemma":[0.9992923,0.000023568335,0.00009464993,0.00048764204,0.000023108198,0.000078703466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038881932,0.00016764287,0.0001531469,0.000036064073,0.000042144984,0.00001477095,0.00016277774,0.00014010143,0.000009666459],"category_scores_gemma":[0.000046231457,0.0001003549,0.00006822762,0.00005918341,0.000027839591,0.0000026821328,0.00004832772,0.00006130362,0.000005139923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016020615,0.000038052614,0.00088821596,0.000045523855,0.000015379495,0.0002911949,0.00007776898,0.00067971885,0.97050005,0.000007885353,0.026910951,0.0005292602],"study_design_scores_gemma":[0.00035950454,0.000056372868,0.00037848242,0.000049462076,0.000031188087,0.0007454794,0.00015691058,0.002722356,0.9255328,0.000014016367,0.06965192,0.00030147424],"about_ca_topic_score_codex":0.000042652446,"about_ca_topic_score_gemma":0.000025993673,"teacher_disagreement_score":0.053781874,"about_ca_system_score_codex":0.000018274979,"about_ca_system_score_gemma":0.000052256935,"threshold_uncertainty_score":0.4092354},"labels":[],"label_agreement":null},{"id":"W2551013397","doi":"10.1182/blood.v126.23.4422.4422","title":"In Vivo Genome Editing in Neonatal Mouse Liver Preferentially Utilizes Homology Directed Repair","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Zinc finger nuclease; Homology (biology); Genome editing; Homology directed repair; Biology; Gene; Zinc finger; In vivo; Molecular biology; DNA; Nuclease; Cell biology; Genome; DNA repair; Genetics; Nucleotide excision repair; Transcription factor","score_opus":0.010808936989615272,"score_gpt":0.2542070559458054,"score_spread":0.24339811895619012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2551013397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660623,0.0021983634,0.00026344848,0.000015316771,0.00013245932,0.00011213199,0.000014404196,0.000039464623,0.0006181863],"genre_scores_gemma":[0.9978081,0.00010861477,0.001223652,0.000034943165,0.0002630608,0.000019727779,0.0000383862,0.000019182933,0.00048434493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991993,0.000039345745,0.00017947973,0.00026846115,0.00007240915,0.00024105796],"domain_scores_gemma":[0.99966294,0.000006570128,0.000026242395,0.00020143302,0.000034665194,0.000068135065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013052233,0.00011595195,0.00012704167,0.00007103951,0.000011539801,0.0000074447685,0.00011368714,0.00013438762,0.000024792824],"category_scores_gemma":[0.00009512239,0.00012584931,0.000044284778,0.00008345434,0.000024821986,0.0000035692901,0.000112097274,0.00009117687,0.00000480399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007533589,0.00027472238,0.014193627,0.00004344788,0.00006583068,0.00012981832,0.00073602854,0.0008800301,0.9825155,0.000025247817,0.0007105046,0.00034990665],"study_design_scores_gemma":[0.003691835,0.00032067334,0.011331787,0.000018062587,0.00003028895,0.000080551516,0.00024231085,0.0005349706,0.96032083,0.000030240435,0.023021761,0.00037666413],"about_ca_topic_score_codex":0.00010508572,"about_ca_topic_score_gemma":0.00081684464,"teacher_disagreement_score":0.022311255,"about_ca_system_score_codex":0.000009605152,"about_ca_system_score_gemma":0.000043986212,"threshold_uncertainty_score":0.5131986},"labels":[],"label_agreement":null},{"id":"W2553481980","doi":"10.1038/nm.4219","title":"Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors","year":2016,"lang":"en","type":"article","venue":"Nature Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":319,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; Interface Biologics (Canada); University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Frizzled; Biology; Wnt signaling pathway; CRISPR; Cancer research; Cell biology; Signal transduction; Genetics; Gene","score_opus":0.007042944432584528,"score_gpt":0.28595923093611997,"score_spread":0.27891628650353545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2553481980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9796878,0.0060496596,0.011307074,0.0008429744,0.00019352202,0.0003005507,0.00002447266,0.00002776108,0.0015661708],"genre_scores_gemma":[0.99744856,0.00018046783,0.00033351872,0.00049433904,0.0005887436,0.000018613322,0.000044793698,0.000036892143,0.00085406133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823797,0.00007167354,0.00045989736,0.000496897,0.00034174745,0.00039178767],"domain_scores_gemma":[0.9987993,0.00012372041,0.00013024984,0.0005587995,0.00020176622,0.00018614145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064211525,0.000263519,0.00044544283,0.000092039314,0.00005935207,0.0000046206333,0.00027182512,0.00032341958,0.0001607274],"category_scores_gemma":[0.0013131041,0.00017480724,0.000114014736,0.00017252352,0.00018156185,0.0000042796773,0.00008249112,0.00029864354,0.0000063755156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008426785,0.000033626315,0.004115702,0.000107493084,0.0000746395,0.000015147666,0.00011695857,0.00004566738,0.99384344,0.000078734665,0.00050648575,0.0009778404],"study_design_scores_gemma":[0.0014589003,0.00065957755,0.012769455,0.00036301313,0.00010713601,0.000056780045,0.0001611839,0.000011790468,0.97471267,0.000687516,0.008715369,0.0002965982],"about_ca_topic_score_codex":0.00007097115,"about_ca_topic_score_gemma":0.00001664847,"teacher_disagreement_score":0.019130755,"about_ca_system_score_codex":0.000037260215,"about_ca_system_score_gemma":0.00009863384,"threshold_uncertainty_score":0.7128432},"labels":[],"label_agreement":null},{"id":"W2555957775","doi":"10.1016/j.mito.2016.11.005","title":"Random shearing as an alternative to digestion for mitochondrial DNA processing in droplet digital PCR","year":2016,"lang":"en","type":"article","venue":"Mitochondrion","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Digital polymerase chain reaction; Mitochondrial DNA; Shearing (physics); Computational biology; Biology; Chemistry; Physics; Genetics; Polymerase chain reaction; Thermodynamics; Gene","score_opus":0.008766059603405131,"score_gpt":0.294714778924747,"score_spread":0.28594871932134186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2555957775","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.729731,0.00007067108,0.26897803,0.00016372513,0.00037796973,0.00048651017,0.000018097744,0.000019257226,0.000154741],"genre_scores_gemma":[0.9953569,0.000013649496,0.0028374153,0.00005210183,0.0008487945,0.00015497366,0.00006572002,0.000035668567,0.00063473155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989266,0.000017410699,0.00021125996,0.00043673723,0.00011989969,0.00028809247],"domain_scores_gemma":[0.99955356,0.000017317268,0.000039932875,0.00020629952,0.000065787586,0.000117118696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006718937,0.00016484922,0.00014690908,0.00008912263,0.000053162177,0.0000740481,0.00014399264,0.0001098882,0.0000053391054],"category_scores_gemma":[0.00023119067,0.00013480353,0.000065161636,0.00007910529,0.000020599415,0.000025109206,0.0000576888,0.000046030065,0.000011329595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005795302,0.000043057415,0.0004400437,0.000011394027,0.0000060990146,0.0000018883508,0.00015636097,0.00067646,0.9581323,0.000017114464,0.00013417634,0.039801527],"study_design_scores_gemma":[0.0055614104,0.0009272333,0.0018474797,0.00019908586,0.000013592219,0.000019331692,0.00009656414,0.00083825807,0.96665645,0.0003259614,0.023037143,0.0004774813],"about_ca_topic_score_codex":0.000017582408,"about_ca_topic_score_gemma":0.00007317275,"teacher_disagreement_score":0.2661406,"about_ca_system_score_codex":0.00003804745,"about_ca_system_score_gemma":0.00004056703,"threshold_uncertainty_score":0.54971284},"labels":[],"label_agreement":null},{"id":"W2557305965","doi":"10.3389/fmicb.2016.01941","title":"Insight into the ERVK Integrase – Propensity for DNA Damage","year":2016,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Winnipeg","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Integrase; DNA damage; DNA; Biology; Genetics; Computational biology; Virology","score_opus":0.005945923139760385,"score_gpt":0.2446708291912399,"score_spread":0.2387249060514795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557305965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8137166,0.0015235625,0.18228294,0.0008797333,0.00096983864,0.0003991755,0.000028824994,0.000010751812,0.00018860635],"genre_scores_gemma":[0.9901547,0.00022057905,0.007954887,0.00037298427,0.00016784453,0.000063014035,0.00007600627,0.000021209466,0.0009687748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921787,0.000054636566,0.00016143717,0.00029717886,0.000015917232,0.0002529463],"domain_scores_gemma":[0.99956036,0.000018150895,0.000034886838,0.00031534853,0.000039875275,0.000031364925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019860959,0.00013347613,0.0001601805,0.000046925965,0.000053599182,0.0000070263723,0.00026389744,0.0001595843,0.0000070206224],"category_scores_gemma":[0.00011117174,0.00007512473,0.000070105794,0.000055050616,0.00016292487,0.0000022816773,0.00011402582,0.00006519759,0.0000046119967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008529346,0.000016639331,0.00394665,0.000008734834,0.000035210123,0.0000012616342,0.00014898166,0.000007631132,0.9692862,0.0000370842,0.019348854,0.007077466],"study_design_scores_gemma":[0.0006144854,0.00012682105,0.0010983233,0.000012425805,0.000009462526,0.000008669483,0.00006256998,0.000017354596,0.6426912,0.00014997498,0.35507086,0.00013785498],"about_ca_topic_score_codex":0.000010445946,"about_ca_topic_score_gemma":0.00015061583,"teacher_disagreement_score":0.335722,"about_ca_system_score_codex":0.000023865849,"about_ca_system_score_gemma":0.000034851346,"threshold_uncertainty_score":0.30634975},"labels":[],"label_agreement":null},{"id":"W2557601429","doi":"10.4269/ajtmh.16-0726","title":"Results from the Workshop “Problem Formulation for the Use of Gene Drive in Mosquitoes”","year":2016,"lang":"en","type":"article","venue":"American Journal of Tropical Medicine and Hygiene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"International Life Sciences Institute Research Foundation; New Partnership for Africa's Development; Universidade Federal de Pernambuco; Inyuvesi Yakwazulu-Natali; University of Toronto; Universidade de Pernambuco; Wellcome Trust","keywords":"Gene drive; Malaria; Anopheles gambiae; Public health; Vector control; Vector (molecular biology); Process (computing); Cas9; Anopheles; Control (management); CRISPR; Risk analysis (engineering); Biology; Computer science; Medicine; Engineering; Gene; Artificial intelligence; Immunology; Genetics","score_opus":0.02496017217718104,"score_gpt":0.3053311732376884,"score_spread":0.28037100106050733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557601429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90668344,0.00089551735,0.08403759,0.008203557,0.000074682495,0.00008579916,0.000013279568,7.773095e-7,0.0000053303493],"genre_scores_gemma":[0.9938362,0.0010770457,0.004381365,0.00023953352,0.0004357911,0.000002527187,0.0000030567917,0.0000057952725,0.000018647797],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99936604,0.000026385746,0.00032403416,0.00009064737,0.00009326507,0.000099639765],"domain_scores_gemma":[0.99897254,0.00058200327,0.00017746499,0.00014349046,0.00008335146,0.000041145926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011950264,0.00006585358,0.00016369828,0.000023881094,0.000022364884,0.0000039740544,0.000108775464,0.000026115662,0.00000191154],"category_scores_gemma":[0.00048735892,0.000026783733,0.000046186207,0.000065547465,0.0001446679,0.000004558922,0.000022263814,0.000054182416,5.063375e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013483868,0.000040938598,0.014380384,0.000005316315,0.00014606479,0.0000028710638,0.0008383605,0.0012521439,0.56316096,0.00014613618,0.0024255358,0.41625288],"study_design_scores_gemma":[0.0101866545,0.0063493424,0.79370457,0.00059997843,0.0002875789,0.000063129846,0.0025335595,0.0010373418,0.095752984,0.00053515716,0.08865014,0.00029956145],"about_ca_topic_score_codex":0.000053986867,"about_ca_topic_score_gemma":0.000049673923,"teacher_disagreement_score":0.7793242,"about_ca_system_score_codex":0.0000055475575,"about_ca_system_score_gemma":0.00001697675,"threshold_uncertainty_score":0.10922089},"labels":[],"label_agreement":null},{"id":"W2557622858","doi":"10.1182/blood.v120.21.920.920","title":"Targeted Repression of TP53 Promotes Erythropoiesis in Del(5q) MDS and Overcomes Clinical Resistance to Lenalidomide","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Lenalidomide; Molecular biology; Biology; Erythropoiesis; Cancer research; Immunology; Medicine; Internal medicine; Anemia; Multiple myeloma","score_opus":0.011849090905171143,"score_gpt":0.33018588557214357,"score_spread":0.3183367946669724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557622858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924123,0.006550901,0.00057287724,0.00007140664,0.00007295498,0.00011835981,0.000007465274,0.000005990263,0.00018772221],"genre_scores_gemma":[0.99450284,0.00035377903,0.0048139896,0.000038999187,0.00012194401,0.000009365364,0.000008229006,0.000012127947,0.00013873949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925935,0.000041591626,0.00025478753,0.0001952275,0.00006907399,0.00017999054],"domain_scores_gemma":[0.99958587,0.000025130017,0.000041889034,0.00023656055,0.000024137511,0.0000864137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029078688,0.000089549,0.00016054281,0.00003315761,0.000016771726,0.0000045174297,0.00007011696,0.00010105374,0.000006441417],"category_scores_gemma":[0.0002481547,0.00008247207,0.0000435078,0.00006323214,0.000035307443,0.000003258602,0.00009488756,0.000053670934,9.953072e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089264344,0.000245579,0.27417278,0.00006199032,0.000039497198,0.0000015521549,0.00013279231,0.000021140382,0.7238373,0.000021518292,0.00051921123,0.0008573814],"study_design_scores_gemma":[0.00082588755,0.0000985968,0.23776536,0.000054156735,0.000024180408,0.0000038723383,0.00004173369,0.0000052305204,0.7578571,0.00001878804,0.0031845137,0.00012057763],"about_ca_topic_score_codex":0.000013357443,"about_ca_topic_score_gemma":0.000039105307,"teacher_disagreement_score":0.036407415,"about_ca_system_score_codex":0.0000023739472,"about_ca_system_score_gemma":0.000013345434,"threshold_uncertainty_score":0.33631134},"labels":[],"label_agreement":null},{"id":"W2558538885","doi":"10.1002/sctm.16-0158","title":"A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing","year":2016,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs","keywords":"CRISPR; Genome editing; Computational biology; Genetics; Gene; Cas9; Biology; Pipeline (software); Bioinformatics; Computer science","score_opus":0.008217826052900503,"score_gpt":0.2483089302991246,"score_spread":0.2400911042462241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2558538885","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11610711,0.0008754689,0.87670374,0.004979963,0.0002692374,0.000371227,0.00010229941,0.000035326506,0.00055561576],"genre_scores_gemma":[0.9922152,0.00017382251,0.0055338163,0.0005670688,0.00047567012,0.000021450413,0.000091621645,0.000040743656,0.0008806033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987893,0.00001650515,0.00026152693,0.00038752615,0.00028123104,0.00026390582],"domain_scores_gemma":[0.9994864,0.000051507006,0.00003898536,0.00018096804,0.00007830976,0.00016382714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106171654,0.00021023926,0.00017182373,0.000063885345,0.00006325736,0.000004986834,0.00012369592,0.00006840951,0.0000535534],"category_scores_gemma":[0.000015997723,0.00014071762,0.00003926266,0.000099451565,0.000060693586,0.000004412668,0.000020629812,0.00005617826,0.0000080433265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000195501,0.000029252,0.00018985839,0.000031980595,0.000035652163,0.000010522545,0.0002959917,0.067435674,0.8799695,0.000010593506,0.002368592,0.049426924],"study_design_scores_gemma":[0.006133979,0.0012194223,0.00041419553,0.0002847985,0.00009961366,0.000095464,0.00032026903,0.029207429,0.8561321,0.00006943122,0.10507249,0.00095080066],"about_ca_topic_score_codex":0.0000035704832,"about_ca_topic_score_gemma":0.000034871642,"teacher_disagreement_score":0.8761081,"about_ca_system_score_codex":0.000009621944,"about_ca_system_score_gemma":0.000054735898,"threshold_uncertainty_score":0.57382977},"labels":[],"label_agreement":null},{"id":"W2559722650","doi":"10.1071/rdv29n1ab70","title":"70 XBP1 DYSREGULATION BY CRISPR/Cas9-MEDIATED GENE EDITING DURING PORCINE EMBRYO EARLY DEVELOPMENT","year":2016,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"XBP1; Biology; Unfolded protein response; Cell biology; Endoplasmic reticulum; Cas9; Embryo; CRISPR; Molecular biology; Genetics; Gene; RNA; RNA splicing","score_opus":0.007998385453010851,"score_gpt":0.2418763355962136,"score_spread":0.23387795014320276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2559722650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9764823,0.0010044643,0.021593045,0.000313217,0.0003043683,0.00019864421,0.000004975025,0.000056400004,0.000042633746],"genre_scores_gemma":[0.9952033,0.00008579738,0.0029182658,0.000024057264,0.00021513767,0.00003856267,0.00011992461,0.00002177253,0.0013731841],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832356,0.000029870094,0.00041217846,0.0007387514,0.00019992985,0.00029570368],"domain_scores_gemma":[0.9993364,0.000007662933,0.00008399135,0.00033172284,0.00011666961,0.00012354505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038293813,0.00020587319,0.00015320003,0.000058379468,0.0002204474,0.00002573386,0.00007164884,0.00011975171,0.000027317732],"category_scores_gemma":[0.00014453752,0.00017328605,0.000025802126,0.000084923195,0.00004344837,0.000015181167,0.000108282184,0.0000594433,0.0000179791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012352224,0.000045779787,0.011745228,0.000045329136,0.00004917085,0.0000010809212,0.00028290413,0.000023902387,0.9627164,6.8417626e-7,0.0003266502,0.02463934],"study_design_scores_gemma":[0.00038402577,0.000021080192,0.36677244,0.000018689105,0.0000037565976,0.000008870702,0.000030498453,0.0000036598528,0.61588913,0.0000029183427,0.016703151,0.0001617964],"about_ca_topic_score_codex":0.0000068977497,"about_ca_topic_score_gemma":0.000008186948,"teacher_disagreement_score":0.3550272,"about_ca_system_score_codex":0.00006609676,"about_ca_system_score_gemma":0.0000787351,"threshold_uncertainty_score":0.70664006},"labels":[],"label_agreement":null},{"id":"W2560266955","doi":"10.1038/mt.2016.191","title":"Gene Editing for Duchenne Muscular Dystrophy Using the CRISPR/Cas9 Technology: The Importance of Fine-tuning the Approach","year":2016,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"Dystrophin; Duchenne muscular dystrophy; Exon; Genome editing; Nonsense mutation; Muscular dystrophy; CRISPR; Genetics; Biology; Exon skipping; Gene; Molecular biology; Utrophin; Mutation; Alternative splicing; Missense mutation","score_opus":0.01367872603796289,"score_gpt":0.2802106464241298,"score_spread":0.2665319203861669,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560266955","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11720311,0.030775933,0.69106936,0.1578629,0.0006728004,0.0021219738,0.00014434449,0.000050433773,0.00009913856],"genre_scores_gemma":[0.6424182,0.003000967,0.04607447,0.2730372,0.02926728,0.0024232774,0.001296782,0.001296319,0.0011854968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978549,0.00013293418,0.00044875726,0.00062786567,0.0003103321,0.00062523276],"domain_scores_gemma":[0.9976433,0.000061413215,0.0003560173,0.0016955644,0.00021544096,0.000028280636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005606996,0.00049025903,0.0003832605,0.000081708655,0.0003242041,0.000051974337,0.001243236,0.0007011014,0.0000061250503],"category_scores_gemma":[0.000099079116,0.00024440602,0.00048552718,0.00022610632,0.00037135708,0.0000034340082,0.0002011732,0.00069202937,7.4966226e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032375832,0.000015368427,0.000054962355,0.000068626345,0.0005934111,0.000018312905,0.00007058851,0.001145049,0.9731597,0.00005725927,0.020861277,0.0039230864],"study_design_scores_gemma":[0.00061153655,0.0001281335,0.000008565987,0.00004495015,0.00011735768,0.00008373089,0.000092361566,0.0007299697,0.52660084,0.0002594964,0.47096202,0.00036101934],"about_ca_topic_score_codex":0.000008847638,"about_ca_topic_score_gemma":0.0000016589448,"teacher_disagreement_score":0.6449949,"about_ca_system_score_codex":0.000024056018,"about_ca_system_score_gemma":0.000084572246,"threshold_uncertainty_score":0.9966588},"labels":[],"label_agreement":null},{"id":"W2560511456","doi":"10.1016/j.cell.2016.11.017","title":"Naturally Occurring Off-Switches for CRISPR-Cas9","year":2016,"lang":"en","type":"letter","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":414,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; CRISPR; Cas9; Computational biology; Genetics; Gene","score_opus":0.008251045516481486,"score_gpt":0.2743337778846146,"score_spread":0.2660827323681331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560511456","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.048687972,0.1093835,0.26827148,0.5059521,0.019271791,0.005750525,0.0025153924,0.00053250097,0.0396347],"genre_scores_gemma":[0.06082582,0.0018147468,0.008110882,0.76862645,0.05936426,0.000448987,0.0031737646,0.0006862314,0.096948855],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99872416,0.000011105412,0.00020219674,0.00049636484,0.00011247282,0.00045368777],"domain_scores_gemma":[0.9992882,0.000028631373,0.00007665554,0.00047733355,0.00007834054,0.000050826628],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000079135054,0.00030892488,0.00022203499,0.00004984092,0.000051282186,0.000030539315,0.00033068043,0.00077116303,0.000030433175],"category_scores_gemma":[0.00003390608,0.00026119075,0.00023452894,0.000025435505,0.000031110347,0.0000015186854,0.00010928449,0.00032619774,0.000033374283],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000870769,0.0000035555825,0.000011772563,0.00019428927,0.000030557152,0.000006834743,0.000009297504,0.0000069133216,0.24293855,7.055426e-7,0.755066,0.0017228206],"study_design_scores_gemma":[0.0002497218,0.00005877426,0.000006877313,0.000031235366,0.000027658485,0.0000060835378,0.000003942454,0.000009306223,0.31594938,0.000022590717,0.68335456,0.00027988802],"about_ca_topic_score_codex":0.0000022096613,"about_ca_topic_score_gemma":0.000002857208,"teacher_disagreement_score":0.2626743,"about_ca_system_score_codex":0.000015906278,"about_ca_system_score_gemma":0.000069805814,"threshold_uncertainty_score":0.999984},"labels":[],"label_agreement":null},{"id":"W2560886376","doi":"10.1101/089763","title":"The Aquarius/EMB-4 helicase licenses co-transcriptional gene silencing","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Cancer Research UK; National Institutes of Health; Government of the United Kingdom; Canada Research Chairs; Wellcome Trust","keywords":"Argonaute; Biology; Piwi-interacting RNA; RNA Helicase A; Transposable element; Gene silencing; Trans-acting siRNA; RNA; Genetics; RNA silencing; Small RNA; RNA-induced transcriptional silencing; Gene; RasiRNA; Intron; RNA interference; Transcription (linguistics); Genome; Helicase","score_opus":0.009282243216916487,"score_gpt":0.25229993289411495,"score_spread":0.24301768967719847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560886376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95534545,0.011122024,0.030241253,0.00038027027,0.001744618,0.0005430372,0.000429284,0.00015604796,0.00003801096],"genre_scores_gemma":[0.9942716,0.0021431118,0.00131383,0.00019965385,0.0017328958,0.00016918483,0.0000022383563,0.00013284235,0.000034661458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99749273,0.00009477511,0.00047870303,0.00093375647,0.0003418085,0.00065822684],"domain_scores_gemma":[0.9977822,0.000052373194,0.00019602236,0.001401939,0.00030816247,0.00025930756],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047426077,0.0005457671,0.00032421487,0.0000863746,0.00032915705,0.0002233396,0.0006561437,0.0005547878,0.000024302772],"category_scores_gemma":[0.00016718343,0.00044188168,0.0002575513,0.0001153836,0.00017083924,0.000008188633,0.00032574372,0.0004160225,0.00006053747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041306535,0.000037521135,0.00042801647,0.00008237185,0.00016368796,0.000016444419,0.0000046046985,0.00014174043,0.99791396,0.00017488669,0.0009875732,0.0000078736875],"study_design_scores_gemma":[0.00038084533,0.00006527841,0.00939938,0.000120214674,0.00006157846,1.513789e-7,0.0000037703926,0.00008262418,0.9466338,0.0000024893595,0.042626556,0.000623305],"about_ca_topic_score_codex":0.000014591362,"about_ca_topic_score_gemma":0.000004616132,"teacher_disagreement_score":0.051280163,"about_ca_system_score_codex":0.00007919056,"about_ca_system_score_gemma":0.0004136019,"threshold_uncertainty_score":0.9998033},"labels":[],"label_agreement":null},{"id":"W2561038183","doi":"10.1128/microbe.9.204.1","title":"CRISPR-Cas Systems: Making the Cut","year":2014,"lang":"en","type":"article","venue":"Microbe Magazine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Computer science; Computational biology; Biology; Genetics; Gene","score_opus":0.006822451885739949,"score_gpt":0.2772290932668746,"score_spread":0.2704066413811347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2561038183","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30983126,0.012050316,0.6521528,0.0013615265,0.0016300662,0.0005566437,0.000026721527,0.000102763595,0.022287905],"genre_scores_gemma":[0.99553347,0.000058322556,0.00055460463,0.00040284873,0.00055325066,0.000014257939,0.000026245825,0.00002797194,0.0028290148],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992838,0.000038551854,0.00015335187,0.00022432786,0.00006803037,0.000231928],"domain_scores_gemma":[0.9994572,0.000011321419,0.000036027395,0.0004190496,0.00004180019,0.00003461375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020266695,0.00013576954,0.00010604689,0.00002264352,0.000077509205,0.000047069327,0.00021288644,0.00007509866,0.000019864068],"category_scores_gemma":[0.000045688208,0.00010155101,0.00006283692,0.00005981168,0.00003761424,0.0000012613862,0.00012229822,0.00008014374,0.00011518302],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000102758,0.000012835385,0.00038639657,0.00004015371,0.000026507336,0.0000015306413,0.000043431464,0.0013379303,0.94251823,0.00018727664,0.05410708,0.0013283307],"study_design_scores_gemma":[0.0002594848,0.00006910529,0.0021063467,0.000022835926,0.000020578076,0.00007698924,0.000033601427,0.001107945,0.1954377,0.000011220547,0.8006674,0.00018679707],"about_ca_topic_score_codex":0.000008747374,"about_ca_topic_score_gemma":0.000021384605,"teacher_disagreement_score":0.74708056,"about_ca_system_score_codex":0.000007857964,"about_ca_system_score_gemma":0.000010595034,"threshold_uncertainty_score":0.41411301},"labels":[],"label_agreement":null},{"id":"W2562765584","doi":"10.1089/humc.2016.29019.per","title":"User-Friendly Technology the Key to Gene-Editing's Bloom: Market for Gene-Editing Tools Estimated at $608m and Growing as New Applications Are Found","year":2016,"lang":"en","type":"editorial","venue":"Human Gene Therapy Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Innovation, Science and Economic Development Canada","funders":"","keywords":"Key (lock); User Friendly; Genome editing; Computer science; Gene; Download; World Wide Web; Biology; Genetics; CRISPR; Operating system","score_opus":0.03171068162398359,"score_gpt":0.382900122455972,"score_spread":0.3511894408319884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2562765584","genre_codex":"empirical","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.54863507,0.015927574,0.14845832,0.0040507885,0.27063692,0.010066086,0.0010340102,0.0005887034,0.000602545],"genre_scores_gemma":[0.008403012,0.0065811113,0.11530505,0.0018408368,0.84237117,0.0045936247,0.00338598,0.0006722341,0.016846964],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960621,0.00008743441,0.0012707295,0.0013849065,0.0004302309,0.00076461793],"domain_scores_gemma":[0.9972837,0.00050601695,0.00048757225,0.00096327515,0.00035952308,0.00039993826],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011356012,0.000672351,0.00071343937,0.00014297212,0.0007009961,0.00014937206,0.0009097509,0.0012587815,0.00006197363],"category_scores_gemma":[0.0011810762,0.00053706433,0.00023622836,0.00016034246,0.00018048013,0.000010142687,0.00068333047,0.0004314915,0.000028125165],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026059488,0.00008932573,0.00047069913,0.00007348707,0.00068495114,0.0000085154625,0.000095921445,0.000039463077,0.09187182,0.000028085484,0.854928,0.05144913],"study_design_scores_gemma":[0.001745852,0.00039089308,0.00070282834,0.00011995489,0.00006491048,0.000017246211,0.000032436536,0.0000051396773,0.09192748,0.00012423069,0.9042342,0.00063486124],"about_ca_topic_score_codex":0.000007070904,"about_ca_topic_score_gemma":0.00006627964,"teacher_disagreement_score":0.57173425,"about_ca_system_score_codex":0.00011177455,"about_ca_system_score_gemma":0.0005924644,"threshold_uncertainty_score":0.9997081},"labels":[],"label_agreement":null},{"id":"W2562772129","doi":"10.1016/s1525-0016(16)33908-9","title":"299. Efficient Functional Oxidase Correction after CRISPR-Oligomer Gene Repair in X-CGD Patient Hematopoietic Stem Cells (HSC) Using Non-Viral, cGMP Compliant, Scalable, Closed System","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biology; Genome editing; CRISPR; Genetic enhancement; Stem cell; Hematopoietic stem cell; Viral vector; Cas9; Gene; Haematopoiesis; Molecular biology; Genetics","score_opus":0.013579354903624446,"score_gpt":0.2534261298596158,"score_spread":0.23984677495599138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2562772129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88147146,0.0034041363,0.11339181,0.0000151160475,0.0010840431,0.0004978746,0.000018405113,0.000046801782,0.000070371636],"genre_scores_gemma":[0.9983631,0.000040545896,0.00094246556,0.0002454546,0.000107972526,0.00008756527,0.000041881594,0.00007278312,0.00009824374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980397,0.0001236906,0.00044659287,0.0006022573,0.00034822972,0.00043948894],"domain_scores_gemma":[0.9989865,0.000007931701,0.00010139294,0.0005573355,0.00015225493,0.00019459164],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024454555,0.00034527658,0.00029643966,0.00014129691,0.00006575521,0.00003446565,0.0001294246,0.0002078863,0.000010250495],"category_scores_gemma":[0.000005437156,0.0003437102,0.00021044981,0.000227846,0.00004905928,0.000005511674,0.00008201441,0.00015167205,0.000028307146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034927923,0.00018474575,0.0003927526,0.00004488975,0.00006834046,0.00008514814,0.00018792314,0.13059713,0.86701035,0.0000034049094,0.0004974437,0.0005786107],"study_design_scores_gemma":[0.0015963286,0.00033975832,0.0005950454,0.000085080435,0.00002363285,0.000099792655,0.0003049884,0.048883807,0.9453106,0.0000021439282,0.0023339463,0.00042490216],"about_ca_topic_score_codex":0.00008257228,"about_ca_topic_score_gemma":0.000005600773,"teacher_disagreement_score":0.116891645,"about_ca_system_score_codex":0.00014400313,"about_ca_system_score_gemma":0.00009607607,"threshold_uncertainty_score":0.9999015},"labels":[],"label_agreement":null},{"id":"W2563140273","doi":"10.1073/pnas.1616343114","title":"Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease","year":2016,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Nuclease; Biology; Genome editing; Transcription activator-like effector nuclease; DNA; Genetics; Computational biology; Non-homologous end joining; Oligonucleotide; Genome; Molecular biology; DNA repair; Gene","score_opus":0.037469834339065713,"score_gpt":0.32871304866037243,"score_spread":0.29124321432130673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2563140273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979652,0.00007196522,0.0001351618,0.0008456413,0.000015267206,0.00010490685,0.0000193812,0.000006900402,0.0008355691],"genre_scores_gemma":[0.9957956,0.000034532033,0.0038338907,0.00006264661,0.00017915573,0.0000062423283,4.4352228e-7,0.0000068213094,0.00008068681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989563,0.0000046850287,0.00019617345,0.00023219716,0.00046207695,0.00014855531],"domain_scores_gemma":[0.9995562,0.000016849963,0.00016520091,0.000012658149,0.00019927541,0.000049859515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004906029,0.00008689444,0.00008331975,0.00006773336,0.00012516585,0.000011958975,0.00034517256,0.000060658127,0.000007055837],"category_scores_gemma":[0.00029573447,0.000050546296,0.000043842512,0.00019749132,0.00025582552,0.000032571443,0.00009887365,0.000051894032,5.2582595e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014651714,0.000020258562,0.0021016547,0.000017014572,0.000013330349,6.4952603e-9,0.00006096605,0.0003356889,0.996032,0.0005187477,0.00008606499,0.00079961773],"study_design_scores_gemma":[0.00029197842,0.00015391358,0.03353974,0.00009191784,0.0000144802325,0.000023560984,0.00016302837,0.0002930256,0.96374387,0.0011157398,0.00045373722,0.000114997725],"about_ca_topic_score_codex":0.0000023644004,"about_ca_topic_score_gemma":1.3553874e-7,"teacher_disagreement_score":0.032288115,"about_ca_system_score_codex":0.000016783522,"about_ca_system_score_gemma":0.0000347401,"threshold_uncertainty_score":0.2061218},"labels":[],"label_agreement":null},{"id":"W2565299518","doi":"10.1016/s1525-0016(16)32948-3","title":"139. Development of a Therapy for Duchenne Muscular Dystrophy Using Either TALEN of Cas9 Proteins","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Transcription activator-like effector nuclease; Genome editing; CRISPR; Cas9; Biology; Dystrophin; Duchenne muscular dystrophy; Genetics; Exon; Gene; Stop codon; Exon skipping; Muscular dystrophy; Computational biology","score_opus":0.014775631356734337,"score_gpt":0.2964885862540888,"score_spread":0.2817129548973545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565299518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6866549,0.002219962,0.31055337,0.000022821017,0.000038246377,0.00047472853,0.000013637335,0.0000058029236,0.000016533879],"genre_scores_gemma":[0.96440876,0.00021964795,0.03506166,0.00003681247,0.00005210183,0.00008455516,0.000012392009,0.000052367857,0.000071694914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901897,0.000030540825,0.00029734627,0.00027889546,0.00014159697,0.00023264425],"domain_scores_gemma":[0.99931145,0.000007058118,0.000111461,0.00038242489,0.00013730307,0.00005031675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016003214,0.00018941557,0.00021794309,0.00005718121,0.0000336417,0.000004952915,0.00018297536,0.00011650798,0.000020102423],"category_scores_gemma":[0.000017393551,0.00013811681,0.00017521586,0.0000720959,0.00006048427,0.0000027963756,0.00003273477,0.000026898138,8.3280554e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019944274,0.000088056,0.00013240331,0.000026852806,0.0002161944,0.0000013289037,0.000121852296,0.00014732755,0.9621376,0.000027254166,0.0000073094416,0.036894396],"study_design_scores_gemma":[0.0019151958,0.00040062203,0.0004245572,0.000039643557,0.000008133418,0.0000041074327,0.000018002716,0.00003268274,0.98119026,0.000046151694,0.015727034,0.00019363145],"about_ca_topic_score_codex":0.000009278327,"about_ca_topic_score_gemma":0.0000023334946,"teacher_disagreement_score":0.27775386,"about_ca_system_score_codex":0.000013174615,"about_ca_system_score_gemma":0.0000921024,"threshold_uncertainty_score":0.563224},"labels":[],"label_agreement":null},{"id":"W2565894557","doi":"10.1534/genetics.116.193870","title":"Multiple Transcriptional and Post-transcriptional Pathways Collaborate to Control Sense and Antisense RNAs of <i>Tf2</i> Retroelements in Fission Yeast","year":2016,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Biology; Genetics; Yeast; Schizosaccharomyces; Sense (electronics); Transcriptional regulation; Computational biology; Saccharomyces cerevisiae; Schizosaccharomyces pombe; Gene; Transcription factor","score_opus":0.006427912769358209,"score_gpt":0.23952324291377305,"score_spread":0.23309533014441486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565894557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98560673,0.0012402972,0.011915962,0.0002753065,0.00008664445,0.00021383254,0.0006392418,0.000004783478,0.000017215709],"genre_scores_gemma":[0.99683636,0.00066245743,0.002157894,0.00016747777,0.000059542574,0.0000086988475,0.000030890453,0.000016521977,0.000060165545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991758,0.000033038337,0.00022251214,0.00025596068,0.00012249139,0.00019022259],"domain_scores_gemma":[0.9996096,0.000013516223,0.00003197678,0.00013460779,0.0000944456,0.00011589042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111750676,0.00012973262,0.00013802316,0.00005873554,0.000027564794,0.00000891392,0.000037492482,0.000089029665,0.000007826666],"category_scores_gemma":[0.000041429277,0.00011172828,0.000027954167,0.0000680146,0.000052453408,0.0000030048202,0.000027559541,0.00003438883,0.0000010803034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001828962,0.000031083055,0.013843254,0.000023123013,0.00001771236,0.000004890653,0.0000914557,0.0001773776,0.9832317,0.00003150198,0.00009302894,0.0022719274],"study_design_scores_gemma":[0.0033747498,0.00048519697,0.2846145,0.00006563308,0.000019944937,0.000035948848,0.00007815505,0.0002622056,0.70211506,0.00003253738,0.008689271,0.00022680192],"about_ca_topic_score_codex":0.0000060161824,"about_ca_topic_score_gemma":0.00010199078,"teacher_disagreement_score":0.28111672,"about_ca_system_score_codex":0.000007730489,"about_ca_system_score_gemma":0.000036234407,"threshold_uncertainty_score":0.45561472},"labels":[],"label_agreement":null},{"id":"W2566444561","doi":"10.1038/srep38968","title":"A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Occupational Cancer Research Centre; Institute for Research in Immunology and Cancer; McGill University","funders":"Canadian Cancer Society Research Institute","keywords":"CRISPR; Suppressor; Cas9; Computational biology; Biology; Computer science; Genetics; Gene","score_opus":0.009601333199828277,"score_gpt":0.2661813204443528,"score_spread":0.2565799872445245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2566444561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711628,0.0006662235,0.02038235,0.00020480614,0.0060752374,0.00018485778,0.00001864805,0.0000491191,0.001255938],"genre_scores_gemma":[0.9799732,0.000008323079,0.00026702668,0.000034507702,0.00028202683,0.000022059481,0.000093821705,0.000020902431,0.019298112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983548,0.000021010523,0.00029794706,0.0007034659,0.00031582866,0.00030698424],"domain_scores_gemma":[0.9989094,0.000010166869,0.00009581109,0.00071113196,0.00015147746,0.000122005215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045201406,0.00014833859,0.00011496964,0.00008399703,0.00017738284,0.00011947092,0.0001283542,0.00006626248,0.00030698074],"category_scores_gemma":[0.000208428,0.00010941646,0.00012141932,0.00012560535,0.00017548974,0.000010317599,0.0001429331,0.000041984764,0.000047482506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012698421,0.000018487897,0.0034402024,0.00000901899,0.000021538945,0.00007837608,0.00001560018,0.000071128015,0.9037402,0.000013507538,0.091800146,0.00077907636],"study_design_scores_gemma":[0.00015403605,0.000026900241,0.0055160825,0.000023893417,0.000012352031,0.0003316672,0.000033010532,0.0000102359245,0.83800215,0.00046670783,0.15523815,0.00018481907],"about_ca_topic_score_codex":0.000009346739,"about_ca_topic_score_gemma":0.000029543435,"teacher_disagreement_score":0.06573807,"about_ca_system_score_codex":0.000012249208,"about_ca_system_score_gemma":0.000079696976,"threshold_uncertainty_score":0.4461874},"labels":[],"label_agreement":null},{"id":"W2566990832","doi":"10.1016/s1525-0016(16)34168-5","title":"559. Spell Checking Nature: A Therapeutic Use of the CRISPR/Cas9 System in Duchenne Muscular Dystrophy","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"CRISPR; Cas9; Duchenne muscular dystrophy; Genome editing; Biology; Dystrophin; Genetics; Gene; Guide RNA; Point mutation; Exon; Computational biology; Mutation","score_opus":0.017698957548221508,"score_gpt":0.28248760550306184,"score_spread":0.26478864795484036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2566990832","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9753985,0.010551167,0.0130396625,0.00009129806,0.0003296738,0.00038017126,0.000006523637,0.000016569516,0.0001864694],"genre_scores_gemma":[0.9986426,0.00014238193,0.0006723265,0.0002897797,0.0000863549,0.000011630251,0.000012043696,0.000052305946,0.00009054747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867606,0.00013693025,0.00027693532,0.0003466416,0.00026499017,0.0002984519],"domain_scores_gemma":[0.9989464,0.000009075403,0.00008849766,0.0007643702,0.00011018351,0.000081471735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025638175,0.00023529374,0.00022796694,0.00006644541,0.00002330183,0.000032960186,0.00034931133,0.0002607129,0.0000032143662],"category_scores_gemma":[0.00004519452,0.00018150786,0.00020362507,0.00025069257,0.0000604264,0.0000054609877,0.00009350297,0.0002379322,0.0000048200627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010130116,0.00006476232,0.0015603169,0.00003142974,0.000105295905,0.000021520107,0.00013994265,0.0063770986,0.98981476,0.0002638903,0.000069988826,0.0014496949],"study_design_scores_gemma":[0.0013269141,0.00017161647,0.0029241012,0.00005470088,0.000020951858,0.000035654804,0.00013731584,0.0008459212,0.9650525,0.00004915356,0.029119194,0.00026199405],"about_ca_topic_score_codex":0.00006291113,"about_ca_topic_score_gemma":0.000012696066,"teacher_disagreement_score":0.029049205,"about_ca_system_score_codex":0.000038470505,"about_ca_system_score_gemma":0.00006912057,"threshold_uncertainty_score":0.74016756},"labels":[],"label_agreement":null},{"id":"W2567060063","doi":"10.1007/978-3-319-48775-5_2","title":"In the Eye of the Beholder","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina; Campion College","funders":"","keywords":"Adaptation (eye); Natural selection; Selection (genetic algorithm); Human eye; Natural (archaeology); Computer science; Computer vision; Artificial intelligence; Optometry; Art; Psychology; Aesthetics; Biology; Neuroscience; Paleontology; Medicine","score_opus":0.008057073093244523,"score_gpt":0.26857243436010453,"score_spread":0.26051536126686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567060063","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013118765,0.0011722639,0.0006679368,0.00062662613,0.00020599365,0.00017407253,0.00001793843,0.0000021358376,0.9958212],"genre_scores_gemma":[0.17300686,0.00024658124,0.000037282516,0.00041129615,0.00022456402,0.000004849561,0.000004860711,0.00001978526,0.8260439],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995995,0.000005883155,0.00011492462,0.000121238045,0.000081087994,0.00007734031],"domain_scores_gemma":[0.9995343,0.0000065112763,0.000033091957,0.00040083154,0.00001598835,0.000009265117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007086823,0.00010053531,0.00007826422,0.000013477006,0.00001083867,0.0000029339672,0.00025009466,0.00014843201,0.00012742166],"category_scores_gemma":[0.000007177514,0.000045425855,0.000096001975,0.0000066538187,0.000045778936,3.0107498e-7,0.00007798251,0.0000696876,0.0000065208073],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048430447,0.000063650885,0.00065979303,0.00018224759,0.0003018453,0.000010772763,0.00029773897,0.00012914553,0.6505211,0.24956214,0.08523609,0.012987016],"study_design_scores_gemma":[0.00014442616,0.000032964243,0.0004106285,0.000040753377,0.000015462549,0.0000045691763,0.000007520631,0.0000011016926,0.063370585,0.0013475944,0.9344981,0.00012634828],"about_ca_topic_score_codex":0.000002695589,"about_ca_topic_score_gemma":0.000029922552,"teacher_disagreement_score":0.84926194,"about_ca_system_score_codex":0.0000025921775,"about_ca_system_score_gemma":0.000017972869,"threshold_uncertainty_score":0.18524127},"labels":[],"label_agreement":null},{"id":"W2567478124","doi":"10.1016/s1525-0016(16)33369-x","title":"561. CRISPR-Induced Deletion (CinDel) Method Allows Permanent and Efficient Restoration of the DMD Gene Reading Frame in Duchenne Patient Myoblasts and Preserves Truncated Dystrophin Structure","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Exon; Duchenne muscular dystrophy; Dystrophin; Exon skipping; Biology; CRISPR; Myogenesis; Gene; Molecular biology; Genetics; Alternative splicing; Exon shuffling","score_opus":0.0057994815439620226,"score_gpt":0.2663999112752608,"score_spread":0.26060042973129877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567478124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788501,0.0013204535,0.01918746,0.00022830308,0.00006984312,0.00032048888,0.000011293512,0.000006161214,0.000005844685],"genre_scores_gemma":[0.9978352,0.0001850649,0.0018326675,0.00006242123,0.00002523538,0.000015116932,0.0000128311185,0.000021698215,0.000009756566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901825,0.00014387352,0.00022011792,0.00030633746,0.00014319709,0.00016821462],"domain_scores_gemma":[0.9995013,0.00001284291,0.000082335624,0.0002998892,0.000056395365,0.00004724394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014450093,0.00015838738,0.00014090064,0.0000529986,0.000040280855,0.000014368635,0.00009824484,0.0001375082,0.00000320473],"category_scores_gemma":[0.00004380318,0.00010315322,0.000044331475,0.00008303175,0.00003594306,0.0000037552247,0.0000699157,0.00007461191,1.2760442e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009713247,0.000025254492,0.00067297235,0.000011530623,0.00003072231,0.0000019757183,0.00029179573,0.002323161,0.9884711,0.000022854138,0.0000054986995,0.008046029],"study_design_scores_gemma":[0.00081454276,0.00027637806,0.016244773,0.000034328274,0.00000890068,0.000012907376,0.00003357115,0.0008649261,0.98134494,0.00006439053,0.00016708652,0.00013326273],"about_ca_topic_score_codex":0.00004101916,"about_ca_topic_score_gemma":0.000024899226,"teacher_disagreement_score":0.018985055,"about_ca_system_score_codex":0.000019342882,"about_ca_system_score_gemma":0.000020242647,"threshold_uncertainty_score":0.42064664},"labels":[],"label_agreement":null},{"id":"W2569944120","doi":"10.1016/j.jtho.2016.11.2061","title":"PUB091 Metabolic and Epigenetic Changes Associated with Lung Cancer Using a CRISPR/Cas9 Mouse Model","year":2017,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"KRAS; Epigenetics; Lung cancer; Cancer research; CRISPR; Cancer; Biology; Medicine; Lung; Bioinformatics; Pathology; Gene; Genetics; Internal medicine; Colorectal cancer","score_opus":0.026648645429924105,"score_gpt":0.431932467222229,"score_spread":0.4052838217923049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2569944120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9739258,0.008095001,0.01692931,0.0006168315,0.00021246297,0.00010007951,0.000015411038,0.0000038795324,0.00010121118],"genre_scores_gemma":[0.9923812,0.0022321998,0.004496815,0.00013327382,0.0003236982,0.000006228746,0.0000022433646,0.000029131816,0.00039519274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991362,0.00006191871,0.00022818563,0.00018027126,0.00013158991,0.00026181276],"domain_scores_gemma":[0.9988967,0.0000153348,0.000484079,0.00025749952,0.000209007,0.00013738318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037862564,0.00016052158,0.00035985402,0.000081300626,0.00017180174,0.000052069467,0.00024441426,0.00019132673,0.000006654449],"category_scores_gemma":[0.0001558608,0.00013033424,0.000063479696,0.0000313413,0.00010541297,0.000010312528,0.00011607967,0.0001818658,1.3174815e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043196295,0.00012240057,0.010636943,0.000058659265,0.0006755211,0.00005202728,0.0002945755,0.027950522,0.9287428,0.000009135888,0.00039636964,0.030629085],"study_design_scores_gemma":[0.0022261776,0.0017816749,0.026835341,0.00024104665,0.0015971316,0.000600333,0.0002467773,0.081376456,0.8763885,0.00008389329,0.00783623,0.0007864504],"about_ca_topic_score_codex":0.000026987731,"about_ca_topic_score_gemma":0.00038275053,"teacher_disagreement_score":0.053425934,"about_ca_system_score_codex":0.000044495504,"about_ca_system_score_gemma":0.00022527513,"threshold_uncertainty_score":0.5314876},"labels":[],"label_agreement":null},{"id":"W2574251228","doi":"10.1016/j.csbj.2016.12.006","title":"Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering","year":2017,"lang":"en","type":"review","venue":"Computational and Structural Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba","keywords":"Genome editing; Genome; Computational biology; Synthetic biology; Genome engineering; Gene; Biology; DNA; Computer science; Genetics","score_opus":0.024193606514145313,"score_gpt":0.31685396479971867,"score_spread":0.29266035828557335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2574251228","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028937077,0.90995705,0.08633492,0.00008162253,0.00023279779,0.00036853235,0.000107610904,0.000020307269,0.000003456947],"genre_scores_gemma":[0.015187408,0.9677,0.015175465,0.000010266077,0.0010849054,0.000036444588,0.00072088646,0.000047661702,0.000036950412],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990257,0.000013508621,0.0003315693,0.0003142984,0.00006175795,0.00025317262],"domain_scores_gemma":[0.9994283,0.00003208415,0.00025093666,0.0001393784,0.00007475536,0.00007459603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016211768,0.0002806375,0.00046405292,0.00013785908,0.00034872073,0.00016367434,0.00018633997,0.00042569693,0.000001981477],"category_scores_gemma":[0.000089264475,0.00021666233,0.00014504125,0.00003961971,0.00009932006,0.0000058793867,0.00014061225,0.0002805024,2.9976096e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006057785,0.0000028830787,0.0000016331977,0.00094493385,0.00017263686,0.0000021496885,0.000016491224,0.010919548,0.0019212695,0.00023140285,0.000008427186,0.98577255],"study_design_scores_gemma":[0.0004745893,0.00023445698,0.00036802865,0.00070907414,0.00014118054,0.0032428917,0.00002065179,0.018500807,0.00017416994,0.00079494703,0.97481084,0.00052839005],"about_ca_topic_score_codex":2.3394257e-7,"about_ca_topic_score_gemma":2.5228292e-7,"teacher_disagreement_score":0.98524415,"about_ca_system_score_codex":0.00002240078,"about_ca_system_score_gemma":0.000059624705,"threshold_uncertainty_score":0.88352334},"labels":[],"label_agreement":null},{"id":"W2574578428","doi":"10.1080/21645698.2016.1270489","title":"Genome editing of crops: A renewed opportunity for food security","year":2017,"lang":"en","type":"review","venue":"GM crops & food","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":175,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Quest University Canada","funders":"","keywords":"Genome editing; Genome; Mutagenesis; Biology; Computational biology; Genetic engineering; Biotechnology; Food security; Mutation; Genetics; Gene; Agriculture","score_opus":0.07370891443501797,"score_gpt":0.3839807581539186,"score_spread":0.3102718437189006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2574578428","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010481204,0.9929186,0.0020548126,0.000007955151,0.0005301611,0.000911677,0.0016485926,0.000022015254,0.00085804355],"genre_scores_gemma":[0.012436973,0.9831055,0.0008489972,0.000014310399,0.0016829001,0.00020294462,0.001320967,0.000121105666,0.00026629717],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99804515,0.00006131369,0.0006734528,0.00060329266,0.00015759942,0.00045917567],"domain_scores_gemma":[0.9978736,0.000025936122,0.0005902774,0.0011275811,0.00017971131,0.00020289543],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003962289,0.00048432458,0.0011934983,0.000091092574,0.00016324139,0.00005075166,0.00066327985,0.00057441875,0.000017580078],"category_scores_gemma":[0.00039793138,0.0004672936,0.00079443137,0.00006559605,0.00009930569,0.000003644412,0.00031426715,0.00023272616,0.0000026338978],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008086382,0.00031929777,0.000012447386,0.059289142,0.0028712677,0.000011900125,0.00027734647,0.000024485416,0.0046407646,0.00023981258,0.00244625,0.92978644],"study_design_scores_gemma":[0.000349469,0.0010619956,0.000008371419,0.0010637308,0.0003734745,0.00003382791,0.000024090541,0.0000030366994,0.0018125783,0.00008558667,0.9947239,0.00045994922],"about_ca_topic_score_codex":0.0000110457595,"about_ca_topic_score_gemma":0.00011845071,"teacher_disagreement_score":0.9922776,"about_ca_system_score_codex":0.00002441307,"about_ca_system_score_gemma":0.00041064576,"threshold_uncertainty_score":0.99977785},"labels":[],"label_agreement":null},{"id":"W2577572217","doi":"10.1038/ncomms14112","title":"Rapid generation of hypomorphic mutations","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Golder Associates (Canada); Agriculture and Agri-Food Canada; Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Science Foundation; National Institutes of Health; American Cancer Society","keywords":"Gene; Biology; Coding region; Gene expression; Genetics; Translation (biology); Mutation; Computational biology; Regulation of gene expression; Function (biology); Messenger RNA","score_opus":0.03322991257937323,"score_gpt":0.3534349443360357,"score_spread":0.32020503175666243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2577572217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90915436,0.043301105,0.01502347,0.005972468,0.0008011368,0.000521448,0.0001446352,0.000041151827,0.02504023],"genre_scores_gemma":[0.99047226,0.0011381315,0.00778897,0.000053065287,0.00009604017,0.000015772977,0.00028333894,0.000008447644,0.00014397995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99966353,0.000021478838,0.000107424894,0.00009095038,0.000052620948,0.00006401338],"domain_scores_gemma":[0.99792325,0.000010883841,0.000080549915,0.0018487893,0.00011120593,0.000025331596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008752818,0.00005496416,0.000057723733,0.00002444742,0.00028163602,0.000021456246,0.000638201,0.00013747471,0.000007593448],"category_scores_gemma":[0.00022100279,0.000057581896,0.000043971795,0.000025011737,0.00010589831,0.000003404891,0.00018920464,0.00014238262,0.0000027137835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033289791,0.00004963195,0.0021241596,0.0000052184228,0.000037291655,1.2402056e-7,0.000045285975,0.00015466532,0.98442054,0.002920348,0.0034903656,0.006749071],"study_design_scores_gemma":[0.00049923686,0.000092007744,0.06753366,0.00001543486,0.00004866682,0.000010971926,0.000049312643,0.0034282063,0.70075643,0.00013722634,0.22719769,0.00023118086],"about_ca_topic_score_codex":0.000007825063,"about_ca_topic_score_gemma":0.00018643757,"teacher_disagreement_score":0.2836641,"about_ca_system_score_codex":0.0000035531011,"about_ca_system_score_gemma":0.000028081355,"threshold_uncertainty_score":0.23481216},"labels":[],"label_agreement":null},{"id":"W2577803396","doi":"10.1128/msphere.00340-16","title":"Optimized CRISPR-Cas9 Genome Editing for <i>Leishmania</i> and Its Use To Target a Multigene Family, Induce Chromosomal Translocation, and Study DNA Break Repair Mechanisms","year":2017,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; CRISPR; Genome editing; Cas9; Genetics; Gene; Guide RNA; Recombinase; Homologous recombination","score_opus":0.01774999224538712,"score_gpt":0.2934497100654763,"score_spread":0.2756997178200892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2577803396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94256645,0.0011456416,0.05487424,0.00009937938,0.00017144809,0.0009840684,0.00008113397,0.000035306366,0.000042325417],"genre_scores_gemma":[0.9674834,0.00009250866,0.03152858,0.0001492566,0.00029156505,0.00015326151,0.000039803886,0.000045381068,0.00021625393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998857,0.000024167673,0.00022222729,0.00052072364,0.00009792321,0.00027796635],"domain_scores_gemma":[0.9992096,0.000014864399,0.00007046269,0.00042470524,0.00012408491,0.00015631098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002033236,0.00021656927,0.00022507088,0.000019645664,0.00033828718,0.00013581022,0.000176338,0.0001300741,0.0000074242002],"category_scores_gemma":[0.00014987729,0.00022650731,0.000060218543,0.000027368516,0.00002247781,0.00001738235,0.00014213023,0.00006663568,0.0000013770762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000913826,0.00008130658,0.00038164933,0.000053040476,0.000098018994,0.000009066075,0.0004183992,0.00090066175,0.9966689,0.000016527494,0.0002621402,0.0010189521],"study_design_scores_gemma":[0.007838429,0.0019193754,0.05895419,0.00008507027,0.00018952614,0.00008622566,0.0021780822,0.0076571438,0.89751387,0.000063700594,0.022283569,0.0012308261],"about_ca_topic_score_codex":0.00006793137,"about_ca_topic_score_gemma":0.00012838456,"teacher_disagreement_score":0.099154994,"about_ca_system_score_codex":0.000008530268,"about_ca_system_score_gemma":0.000027131064,"threshold_uncertainty_score":0.92367005},"labels":[],"label_agreement":null},{"id":"W2578246706","doi":"10.1177/153567601301800404","title":"Biosafety, Biosecurity, and Bioethics Governance in Synthetic Biology: The “7P” Approach","year":2013,"lang":"en","type":"article","venue":"Applied Biosafety","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Science Centre for Human and Animal Health","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Biosecurity; Biosafety; Bioethics; Corporate governance; Intervention (counseling); Political science; Engineering ethics; Public health; Public relations; Business; Biotechnology; Law; Engineering; Biology; Medicine","score_opus":0.00912711576088475,"score_gpt":0.273557668649637,"score_spread":0.2644305528887522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2578246706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9241833,0.009053611,0.008719821,0.016777925,0.0005461619,0.0029456648,0.0001609393,0.00013561104,0.037476975],"genre_scores_gemma":[0.99635416,0.0016106066,0.0011915818,0.00046501623,0.00013000396,0.000105593055,0.000055594333,0.000027628383,0.000059830512],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986397,0.00004393086,0.00029681317,0.00052134035,0.00010638371,0.00039180214],"domain_scores_gemma":[0.99926025,0.000042252297,0.00007550527,0.0005097225,0.000030323527,0.000081933744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568146,0.00025079056,0.000212531,0.000036400324,0.000102002545,0.000036483973,0.00030601362,0.00030139228,0.000022666702],"category_scores_gemma":[0.0000401152,0.00018441495,0.00006163232,0.00019185041,0.00047569277,0.0000038276744,0.00032921496,0.00025514947,0.00002489454],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009174377,0.00025975262,0.00822915,0.0001695507,0.0001276467,0.0000017414577,0.00042198598,0.000117517375,0.7444728,0.2090528,0.0014659835,0.03558935],"study_design_scores_gemma":[0.0031006471,0.00037807785,0.62886673,0.0000810266,0.000078541685,0.00009644973,0.001466373,0.0021389467,0.30063224,0.0066283415,0.054478396,0.0020542464],"about_ca_topic_score_codex":0.00013928933,"about_ca_topic_score_gemma":0.000042325944,"teacher_disagreement_score":0.62063754,"about_ca_system_score_codex":0.000014086023,"about_ca_system_score_gemma":0.000031644086,"threshold_uncertainty_score":0.7520223},"labels":[],"label_agreement":null},{"id":"W2580375224","doi":"10.1139/gen-2016-0127","title":"Enhancement of single guide RNA transcription for efficient CRISPR/Cas-based genomic engineering","year":2017,"lang":"en","type":"article","venue":"Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Trans-activating crRNA; Guide RNA; Biology; Subgenomic mRNA; Cas9; RNA; Computational biology; Genome editing; RNA polymerase III; Transcription (linguistics); Genetics; DNA; Genome engineering; genomic DNA; RNA polymerase; Gene","score_opus":0.012064148756922462,"score_gpt":0.27932402404294465,"score_spread":0.2672598752860222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2580375224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5598519,0.000613497,0.4389195,0.000041168645,0.00019100863,0.00018663358,0.00002738744,0.0000062870645,0.0001626514],"genre_scores_gemma":[0.9919213,0.000025938774,0.007538083,0.000025515375,0.00016657382,0.00003859745,0.00006190881,0.000024699244,0.00019737073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928164,0.000004118477,0.00020523228,0.00022133056,0.00007292602,0.00021473228],"domain_scores_gemma":[0.99936783,0.000004887518,0.00007645813,0.00044448886,0.000054949393,0.000051395276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013270571,0.00012318151,0.00012903693,0.00003746646,0.000081784034,0.000022775575,0.0002110967,0.00006693614,0.000011609906],"category_scores_gemma":[0.000036269215,0.00013437778,0.00011315257,0.000014245954,0.000024452576,0.000001501668,0.000033562766,0.000028179764,0.0000030542747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029864432,0.000041270076,0.000015474196,0.00007345259,0.000024531597,3.6901957e-7,0.00003929283,0.041881084,0.95717716,0.000010644972,0.000028743552,0.00067808456],"study_design_scores_gemma":[0.00058052543,0.0002488373,0.0024046644,0.000013297753,0.000023074457,9.977693e-7,0.00001017626,0.0033248828,0.967505,0.0000023419395,0.025734682,0.00015151504],"about_ca_topic_score_codex":0.000009754789,"about_ca_topic_score_gemma":0.0000053204026,"teacher_disagreement_score":0.43206945,"about_ca_system_score_codex":0.000027032183,"about_ca_system_score_gemma":0.00002710622,"threshold_uncertainty_score":0.5479767},"labels":[],"label_agreement":null},{"id":"W2580902218","doi":"10.1016/j.cels.2016.12.011","title":"Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways","year":2017,"lang":"en","type":"article","venue":"Cell Systems","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Aging; National Cancer Institute; National Institutes of Health; JPB Foundation; Parkinson's Disease Foundation; Multiple System Atrophy Coalition; National Human Genome Research Institute; American Brain Foundation; Howard Hughes Medical Institute","keywords":"Gene; Biology; Disease; Genome; Computational biology; Genetics; Medicine","score_opus":0.013036160266628044,"score_gpt":0.25172465635808994,"score_spread":0.2386884960914619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2580902218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76865447,0.01802127,0.20803584,0.0001237672,0.0013431065,0.00060435914,0.00004703381,0.00003507535,0.0031350646],"genre_scores_gemma":[0.9958418,0.0006633854,0.0005955672,0.00009697184,0.0015735336,0.00007754636,0.00008526003,0.000068032205,0.0009978897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856174,0.000051766936,0.00025321558,0.00059408374,0.00014991092,0.00038926906],"domain_scores_gemma":[0.99826264,0.0000050866424,0.00009965392,0.001273222,0.000076633776,0.00028274945],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000111805006,0.00026564897,0.00022348533,0.000023521021,0.00028262628,0.00022060987,0.0005169236,0.00013042305,0.00000846942],"category_scores_gemma":[0.000015597287,0.00026715093,0.0001323012,0.000041698615,0.000050770625,0.000006417566,0.0002658487,0.00009510909,0.00004741781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002809133,0.000024417459,0.00030140742,0.000040014005,0.000019486533,0.000035128716,0.00007327721,0.11715901,0.88099664,0.00005060642,0.00066720886,0.0006046874],"study_design_scores_gemma":[0.00063953374,0.00022690793,0.0062655816,0.000044503067,0.000043823966,0.000010363709,0.0001103705,0.0053260075,0.65642834,0.000014522114,0.33008203,0.0008080288],"about_ca_topic_score_codex":0.000021791044,"about_ca_topic_score_gemma":0.000005814741,"teacher_disagreement_score":0.3294148,"about_ca_system_score_codex":0.000016084368,"about_ca_system_score_gemma":0.000030111905,"threshold_uncertainty_score":0.99997807},"labels":[],"label_agreement":null},{"id":"W2581106579","doi":"10.1016/j.mod.2017.01.004","title":"Zebrafish akt2 is essential for survival, growth, bone development, and glucose homeostasis","year":2017,"lang":"en","type":"article","venue":"Mechanisms of Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"Zebrafish; AKT2; Biology; Morpholino; Cell biology; Homeostasis; AKT1; Genetics; Gene; Signal transduction; Protein kinase B","score_opus":0.01215022979673216,"score_gpt":0.2770579974864437,"score_spread":0.2649077676897116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2581106579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73337144,0.00074230245,0.2649375,0.00014879885,0.00033688612,0.00028467475,0.000021428305,0.000012695555,0.00014428188],"genre_scores_gemma":[0.8950672,0.00018388756,0.10417387,0.00006531719,0.000057342946,0.00005791345,0.000059878977,0.000029921935,0.00030463104],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989093,0.000007637145,0.00029444086,0.00035625356,0.0001598896,0.00027246977],"domain_scores_gemma":[0.9993151,0.000008296516,0.00013808695,0.0003253046,0.00011722287,0.000095996256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002585798,0.00019477437,0.00022304541,0.00005258748,0.0002882387,0.000053897027,0.00024438158,0.00012208607,0.000014177736],"category_scores_gemma":[0.00007222538,0.0002042663,0.000053997017,0.000022355469,0.000040212846,0.00000641745,0.0002757687,0.00003933794,0.000002656516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008273998,0.00007444623,0.00023596323,0.0002063502,0.0001943715,0.0000029221883,0.00046579697,0.0000025125128,0.9606541,0.00072237046,0.00067968736,0.036678765],"study_design_scores_gemma":[0.00081700087,0.000059722846,0.0032407355,0.000027446626,0.000016604305,0.000004794676,0.00008830786,0.000011154693,0.9738108,0.0003536272,0.021301625,0.00026820402],"about_ca_topic_score_codex":0.0000071728427,"about_ca_topic_score_gemma":0.000037839513,"teacher_disagreement_score":0.16169578,"about_ca_system_score_codex":0.000012012333,"about_ca_system_score_gemma":0.00013129486,"threshold_uncertainty_score":0.8329738},"labels":[],"label_agreement":null},{"id":"W2581592259","doi":"10.1038/srep41120","title":"Potential molecular consequences of transgene integration: The R6/2 mouse example","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; CHDI Foundation; Canada Research Chairs; National Institutes of Health; University of Auckland; National Alliance for Research on Schizophrenia and Depression; Neurological Foundation of New Zealand","keywords":"Transgene; Biology; Genome; Gene; Genetics; Computational biology; Genetically modified mouse; Exon","score_opus":0.013419344852686952,"score_gpt":0.28952710533533266,"score_spread":0.2761077604826457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2581592259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96737844,0.00045397054,0.02950325,0.00017595007,0.001639979,0.00014314607,0.0000041959465,0.0000066666353,0.00069440936],"genre_scores_gemma":[0.9977276,0.000015821914,0.0006029259,0.000013062353,0.000059884358,0.000009384507,0.000034681212,0.000008005154,0.001528677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909824,0.000018562363,0.00022622425,0.0003297749,0.0001896655,0.00013754936],"domain_scores_gemma":[0.99854624,0.0000024889803,0.0001576925,0.0011442121,0.00010727872,0.000042059295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004924632,0.00008576724,0.00008655671,0.000022738684,0.00031124917,0.00014965188,0.0002584572,0.0000528878,0.000024946974],"category_scores_gemma":[0.00009030319,0.00006221794,0.000092323906,0.00003328903,0.0005214577,0.0000047703834,0.00006256456,0.00004304442,0.0000012805409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000041328644,0.000011203079,0.00019987127,0.0000057674447,0.000015414418,0.000024788882,0.000055904595,0.0005757276,0.99722016,0.00005602467,0.00062334555,0.0012076682],"study_design_scores_gemma":[0.000061308885,0.000026558433,0.0004414731,0.0000058860082,0.000013578121,0.0000924546,0.000055009248,0.000055060642,0.9901112,0.00049908704,0.008561026,0.00007738223],"about_ca_topic_score_codex":0.000081953825,"about_ca_topic_score_gemma":0.000045733042,"teacher_disagreement_score":0.030349126,"about_ca_system_score_codex":0.0000028729714,"about_ca_system_score_gemma":0.00007074012,"threshold_uncertainty_score":0.25371742},"labels":[],"label_agreement":null},{"id":"W2581771809","doi":"10.1038/s41536-017-0007-2","title":"Human gene editing: revisiting Canadian policy","year":2017,"lang":"en","type":"editorial","venue":"npj Regenerative Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Ottawa Hospital; NeuroDevNet; University of British Columbia; McGill University; University of Ottawa; Institute of Health Economics; McGill Genome Centre; Université de Montréal; University of Alberta; McGill University Health Centre","funders":"","keywords":"Genome editing; Gene; Political science; Biology; Genetics; CRISPR","score_opus":0.01258558102727118,"score_gpt":0.35561214490240517,"score_spread":0.34302656387513397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2581771809","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017853127,0.01725662,0.0017728092,0.003929818,0.93048894,0.00072265544,0.00067089964,0.00006279894,0.043310117],"genre_scores_gemma":[0.018941106,0.0005494311,0.00027612186,0.00015811283,0.95604295,0.000041723863,0.0044968533,0.0001170519,0.019376626],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99749947,0.0000824413,0.00045034618,0.0008034439,0.0004973988,0.0006668839],"domain_scores_gemma":[0.9976548,0.00002867177,0.0003064697,0.0010567281,0.0004707471,0.00048258808],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053290045,0.0005547928,0.00062359835,0.0002801939,0.00059752504,0.00006420456,0.00063985103,0.0009309266,0.000075116586],"category_scores_gemma":[0.002855728,0.0005071163,0.00013617874,0.000090838155,0.00026192344,0.0000036690776,0.00014921465,0.0006273501,0.0000138183805],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003732753,0.000003741859,0.000013150007,0.00006214895,0.00009545508,0.000041600924,0.000084098465,0.000037496313,0.11646592,0.000057400957,0.8817336,0.0014016507],"study_design_scores_gemma":[0.0006526119,0.00027176336,0.000037528443,0.00029785774,0.000072262774,0.000013690778,0.000038131795,0.000013033863,0.04544079,0.000020657115,0.9527008,0.00044087818],"about_ca_topic_score_codex":0.024135906,"about_ca_topic_score_gemma":0.03278113,"teacher_disagreement_score":0.07102513,"about_ca_system_score_codex":0.00016515274,"about_ca_system_score_gemma":0.0011140376,"threshold_uncertainty_score":0.99973804},"labels":[],"label_agreement":null},{"id":"W2583808977","doi":"10.1016/j.bpj.2016.11.416","title":"Live Cell Imaging of Genomic Loci using Fluorescent RNA Aptamers","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Aptamer; Subgenomic mRNA; Live cell imaging; RNA; CRISPR; Fluorescence; Cas9; Systematic evolution of ligands by exponential enrichment; Computational biology; Green fluorescent protein; Biology; Guide RNA; Biophysics; Cell; Molecular biology; Genetics; Gene","score_opus":0.009420318509238988,"score_gpt":0.28414883385162243,"score_spread":0.27472851534238346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583808977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917893,0.00023604429,0.007453142,0.000040597744,0.00022333133,0.000039444367,0.0000052005876,0.0000024321669,0.00021052666],"genre_scores_gemma":[0.9971944,0.00014181825,0.0018761876,0.00002254622,0.0007143438,4.2418296e-7,0.000002709007,0.000016993947,0.000030590843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993866,0.000014099065,0.0001597579,0.00014067144,0.00010358309,0.00019529615],"domain_scores_gemma":[0.9994092,0.0000028638,0.00015459955,0.00027123943,0.000057656936,0.00010443345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006996615,0.00010764334,0.00012454648,0.000022523274,0.00016643948,0.000055535347,0.00026644493,0.00004115445,0.000013149537],"category_scores_gemma":[0.000016447777,0.00010006656,0.00014405116,0.000010434341,0.000096455646,0.0000045227835,0.00012596996,0.000116491385,0.000007077891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020738544,0.00003707345,0.00087085157,0.000011336155,0.000022549957,0.000008563409,0.000034946584,0.00039308995,0.9961866,0.0000039810416,0.0001303107,0.0022799217],"study_design_scores_gemma":[0.00035916961,0.000061688486,0.007941689,0.000014960895,0.000028106371,0.000035020923,0.00006991971,0.0028329305,0.9880583,0.0000093398585,0.00045736312,0.0001314716],"about_ca_topic_score_codex":0.000018073819,"about_ca_topic_score_gemma":6.4726953e-7,"teacher_disagreement_score":0.0081282975,"about_ca_system_score_codex":0.000016221114,"about_ca_system_score_gemma":0.000041796557,"threshold_uncertainty_score":0.40805957},"labels":[],"label_agreement":null},{"id":"W2586144003","doi":"10.1534/g3.116.037739","title":"Variants of the Sir4 Coiled-Coil Domain Improve Binding to Sir3 for Heterochromatin Formation in <i>Saccharomyces cerevisiae</i>","year":2017,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Deutsche Forschungsgemeinschaft","keywords":"Saccharomyces cerevisiae; Biology; Heterochromatin; Chromatin; Gene silencing; Genetics; Mutation; Histone; Histone H4; Cell biology; Yeast; Gene","score_opus":0.011193360806607417,"score_gpt":0.2916015732874605,"score_spread":0.28040821248085307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586144003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9588415,0.024212608,0.015000403,0.00019113696,0.00050887425,0.00087875285,0.00014608052,0.000008344768,0.00021226915],"genre_scores_gemma":[0.98542815,0.0042716465,0.009602119,0.00008937397,0.00025951408,0.000100237594,0.000037601778,0.000042566404,0.00016879148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986079,0.000034123063,0.00044887938,0.00036164667,0.00016358506,0.00038387804],"domain_scores_gemma":[0.9985543,0.000018308478,0.0002664381,0.0009831995,0.00009190921,0.00008586099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025375313,0.00023529175,0.00025867485,0.000067614434,0.00022314151,0.000078484074,0.00073398027,0.00015175166,0.0000053123176],"category_scores_gemma":[0.000030698873,0.00020599019,0.00014958082,0.00007679417,0.00005930349,0.000009154864,0.00038507694,0.00006255159,0.0000045178635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035355675,0.000024133999,0.0022409619,0.00013727724,0.000028679282,5.80317e-7,0.0002022419,0.0022649008,0.89383924,0.000013833158,0.00010592419,0.10110686],"study_design_scores_gemma":[0.0008890849,0.00027671934,0.005656171,0.000058770216,0.00002910746,0.000012257916,0.00019518567,0.00079008454,0.9632823,0.00011310477,0.02837997,0.00031724444],"about_ca_topic_score_codex":0.00000988027,"about_ca_topic_score_gemma":0.00019305521,"teacher_disagreement_score":0.100789614,"about_ca_system_score_codex":0.00002678333,"about_ca_system_score_gemma":0.000047984682,"threshold_uncertainty_score":0.8400036},"labels":[],"label_agreement":null},{"id":"W2586180368","doi":"10.71781/30024","title":"Production de vecteurs viraux efficaces pour la transduction de cellules transformées et de cellules primaires","year":2005,"lang":"fr","type":"dissertation","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Transduction (biophysics); Chemistry; Biochemistry","score_opus":0.010692015779474333,"score_gpt":0.32236861521784244,"score_spread":0.3116765994383681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586180368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9720551,0.007025487,0.013358041,0.00079943496,0.00042588552,0.0006401406,0.00005681749,0.0000060813554,0.005633037],"genre_scores_gemma":[0.9606018,0.0058979327,0.02265921,0.000026862133,0.00083085697,0.00008525558,0.0011771013,0.000089750414,0.008631223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979455,0.00025515995,0.00039656294,0.000707533,0.00015555117,0.0005396918],"domain_scores_gemma":[0.9992885,0.00003624006,0.0001347166,0.00029062765,0.000089032656,0.00016086943],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000741194,0.00044756362,0.00032420625,0.000091210735,0.00016790887,0.00020548937,0.00041660015,0.00067951065,0.00021020506],"category_scores_gemma":[0.00008109498,0.0005058843,0.00019903279,0.00010797893,0.00008427735,0.000024426194,0.000027453254,0.00035993202,0.000030008361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022672827,0.00022744646,0.00021884647,0.00020360251,0.00012152344,0.0000074132813,0.006151988,0.014502996,0.82796484,0.00003954398,0.00013299452,0.15020211],"study_design_scores_gemma":[0.00050748565,0.00015303338,0.0038585817,0.00025096207,0.00025261103,0.00011273098,0.0028036349,0.00046928102,0.8860329,0.000028492716,0.10503041,0.0004998872],"about_ca_topic_score_codex":0.00020358324,"about_ca_topic_score_gemma":0.0022894894,"teacher_disagreement_score":0.14970222,"about_ca_system_score_codex":0.00012272196,"about_ca_system_score_gemma":0.0008568151,"threshold_uncertainty_score":0.9997393},"labels":[],"label_agreement":null},{"id":"W2586249289","doi":"10.1080/21645698.2017.1289305","title":"New GMO regulations for old: Determining a new future for EU crop biotechnology","year":2017,"lang":"en","type":"review","venue":"GM crops & food","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biotechnology; Process (computing); Agricultural biotechnology; Business; Agriculture; Risk analysis (engineering); Biology; Computer science","score_opus":0.04681428010056332,"score_gpt":0.3881809140787686,"score_spread":0.34136663397820527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586249289","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000025102388,0.8798455,0.117447786,0.00023672829,0.0008638743,0.0012176696,0.00023076475,0.000049120765,0.000083449086],"genre_scores_gemma":[0.00007198701,0.9443978,0.042936195,0.000056084915,0.0045069396,0.0002831425,0.00084633427,0.00016729152,0.006734234],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998281,0.0000144786945,0.00044858435,0.00069382903,0.00007665926,0.0004854728],"domain_scores_gemma":[0.9983465,0.000028298757,0.00029713905,0.0010992244,0.000063830696,0.00016500475],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000105147985,0.00047627348,0.000864271,0.00013246688,0.00023301928,0.00008833297,0.00062762544,0.0011508346,0.000010954723],"category_scores_gemma":[0.00016088186,0.00045052738,0.00068854814,0.00008044952,0.000043588803,0.000003638624,0.00017736446,0.00018782481,0.000006171415],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011405012,0.000009311271,3.880875e-7,0.0016943433,0.00023034758,8.5629495e-7,0.000017187405,0.000011125864,0.0005948434,0.00027022412,0.013372078,0.9837879],"study_design_scores_gemma":[0.00056743214,0.000567999,0.0000029818002,0.0007132073,0.00049129355,0.000063558,0.000009066962,0.000010999971,0.002268777,0.00012410192,0.9946795,0.0005010832],"about_ca_topic_score_codex":0.000011630348,"about_ca_topic_score_gemma":0.00010906834,"teacher_disagreement_score":0.9832868,"about_ca_system_score_codex":0.000024110623,"about_ca_system_score_gemma":0.0004984622,"threshold_uncertainty_score":0.99979466},"labels":[],"label_agreement":null},{"id":"W2587028347","doi":"10.1038/nbt.3787","title":"Industrializing rare disease therapy discovery and development","year":2017,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Rare Disease Foundation","keywords":"Disease; Rare disease; Medicine; Internal medicine","score_opus":0.012283372649996955,"score_gpt":0.28877772776129157,"score_spread":0.2764943551112946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2587028347","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09355482,0.15650785,0.0037598908,0.7394739,0.0043088817,0.0013902913,0.00031113016,0.00029016339,0.00040310193],"genre_scores_gemma":[0.45128843,0.024451355,0.006231735,0.464376,0.025219444,0.00036545744,0.007974952,0.000635073,0.019457556],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861944,0.000021839052,0.00017972651,0.0006830429,0.00013613817,0.00035979744],"domain_scores_gemma":[0.99892426,0.0000097039665,0.00012228181,0.00085862103,0.000031512354,0.000053646472],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00007868694,0.00035988513,0.0002743761,0.00013478486,0.00015054925,0.00008621825,0.0004913324,0.0057666884,0.0000055389737],"category_scores_gemma":[0.00014293366,0.0003252536,0.00007067654,0.000035164354,0.0001604332,0.0000037852064,0.00032886138,0.002309579,0.0000033432868],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009317755,0.00002098301,0.0003547116,0.000117239746,0.00027509662,0.0003464807,0.000014096117,0.0000030170581,0.043762676,0.00004264997,0.9081563,0.0468136],"study_design_scores_gemma":[0.00037967224,0.00004921049,0.00030785718,0.000045060326,0.000013797669,0.000028706529,0.0000041551875,9.96273e-7,0.098702595,0.00002340738,0.90008444,0.00036012504],"about_ca_topic_score_codex":0.0000031125956,"about_ca_topic_score_gemma":0.0000039493684,"teacher_disagreement_score":0.3577336,"about_ca_system_score_codex":0.000017498309,"about_ca_system_score_gemma":0.00018333111,"threshold_uncertainty_score":0.99999213},"labels":[],"label_agreement":null},{"id":"W2588162183","doi":"10.1038/srep42551","title":"A ‘selfish’ B chromosome induces genome elimination by disrupting the histone code in the jewel wasp Nasonia vitripennis","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Science Foundation","keywords":"Nasonia vitripennis; Biology; Genetics; Chromatin; Genome; Histone; Chromosome; Gene; Pteromalidae","score_opus":0.011178929751110645,"score_gpt":0.3141288691770944,"score_spread":0.3029499394259838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588162183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948726,0.0013058301,0.0004330606,0.0008762874,0.0014180241,0.0002634437,0.000007130258,0.000008768931,0.0008148319],"genre_scores_gemma":[0.99809265,0.000035650155,0.00010376712,0.00004918505,0.00014783218,0.000044178134,0.00009795494,0.000013211426,0.0014155923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986135,0.00003999707,0.00028831803,0.0004995153,0.00029166712,0.0002670193],"domain_scores_gemma":[0.99836814,0.00001369569,0.00023892263,0.0012763483,0.00006125177,0.000041663505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016926655,0.00012877464,0.00010380951,0.000037139485,0.0007723638,0.00043871798,0.0004932501,0.000083798914,0.000010684423],"category_scores_gemma":[0.0003005552,0.00008536,0.00006563731,0.000094335875,0.00023174933,0.000011853035,0.00015242441,0.00012002427,0.000004092706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000031235993,0.000032563523,0.00063005777,0.000009049916,0.000008561599,0.000034256867,0.0005465532,0.00006405559,0.993078,0.000008882999,0.003564065,0.0020208464],"study_design_scores_gemma":[0.00026631457,0.00006637426,0.034974378,0.000028517283,0.000030436004,0.000314584,0.0005851534,0.00028247552,0.6809803,0.00029420623,0.2818189,0.00035834967],"about_ca_topic_score_codex":0.000053590564,"about_ca_topic_score_gemma":0.00013829763,"teacher_disagreement_score":0.31209767,"about_ca_system_score_codex":0.000026106793,"about_ca_system_score_gemma":0.000054205415,"threshold_uncertainty_score":0.5940476},"labels":[],"label_agreement":null},{"id":"W2588815320","doi":"10.1038/nmicrobiol.2017.18","title":"CRISPR–Cas in the laboratory classroom","year":2017,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Archaea; Nucleic acid; Biology; Computational biology; Bacteria; Trans-activating crRNA; Genetics; Gene; Microbiology; Genome editing","score_opus":0.004010651564084817,"score_gpt":0.30574125962072374,"score_spread":0.3017306080566389,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588815320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886298,0.0059595373,0.0006468698,0.0017050563,0.0007741738,0.00017394469,0.000055435023,0.000009873979,0.0020452954],"genre_scores_gemma":[0.9977478,0.0001197712,0.00027677967,0.001292565,0.00030968263,0.0000102332615,0.0000671946,0.000011708028,0.00016429115],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993342,0.00005308195,0.00010920421,0.00024993918,0.000025583999,0.00022796726],"domain_scores_gemma":[0.99921656,0.000013385529,0.000049046997,0.00066109933,0.00003841544,0.00002147303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002211604,0.00011951246,0.00010951676,0.000028367996,0.00012353944,0.00003165668,0.00056644843,0.00048790095,0.0000107287615],"category_scores_gemma":[0.00014155831,0.000087020395,0.000049565897,0.000031185686,0.00009851755,0.000001957544,0.00011279822,0.00039096017,0.00001421983],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001798829,0.00001880254,0.0052464283,0.000005862731,0.000013186381,0.000010196278,0.000050768824,0.000011232317,0.9812435,0.00015108152,0.012717741,0.0005132443],"study_design_scores_gemma":[0.00047355558,0.00008789557,0.036562342,0.0000066129073,0.0000079947085,0.00006211359,0.000065671324,0.0000041321036,0.4337463,0.00005318603,0.5287596,0.00017056483],"about_ca_topic_score_codex":0.000010346147,"about_ca_topic_score_gemma":0.00027391122,"teacher_disagreement_score":0.54749715,"about_ca_system_score_codex":0.000007710331,"about_ca_system_score_gemma":0.00003203836,"threshold_uncertainty_score":0.3763139},"labels":[],"label_agreement":null},{"id":"W2589116452","doi":"10.1038/nprot.2016.186","title":"Detecting natural adaptation of the Streptococcus thermophilus CRISPR-Cas systems in research and classroom settings","year":2017,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Streptococcus thermophilus; Adaptation (eye); Computational biology; Biology; Synthetic biology; Systems biology; Computer science; Microbiology; Genetics; Bacteria; Neuroscience; Gene","score_opus":0.03816342516754459,"score_gpt":0.4176131860353687,"score_spread":0.3794497608678241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2589116452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685898,0.0014854311,0.00032307726,0.00025797662,0.00017776752,0.028768605,0.0000100525895,0.000008306399,0.00037900792],"genre_scores_gemma":[0.99192566,0.0000055386477,0.00015044064,0.000011487768,0.00014259007,0.0076431446,0.0000021760102,0.000014905559,0.00010406298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907637,0.00007496773,0.00017987256,0.00025484228,0.0002064386,0.00020750804],"domain_scores_gemma":[0.999138,0.00002998783,0.00012176184,0.00052447326,0.00015723423,0.000028567356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006192194,0.00010223085,0.00011601294,0.0000439881,0.0002044478,0.00008067159,0.0003503096,0.0002710157,6.53811e-7],"category_scores_gemma":[0.00054263236,0.00007474051,0.00003549537,0.00006571917,0.00009429763,0.0000061354294,0.0002287249,0.00058282865,2.9107585e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012547227,0.000035867102,0.0387806,0.00033145605,0.000025065612,0.0000032278028,0.00031822984,0.00050448923,0.9455474,0.00016915113,0.00015726541,0.014001799],"study_design_scores_gemma":[0.0011725011,0.0002749865,0.15923631,0.0005172139,0.000005562154,0.00001553883,0.0005706246,0.003578291,0.825879,0.00021198032,0.008329402,0.00020863548],"about_ca_topic_score_codex":0.00007581047,"about_ca_topic_score_gemma":0.00026564335,"teacher_disagreement_score":0.12045571,"about_ca_system_score_codex":0.000016742808,"about_ca_system_score_gemma":0.000043853597,"threshold_uncertainty_score":0.30478296},"labels":[],"label_agreement":null},{"id":"W2589897652","doi":"10.1093/bmb/ldx002","title":"Ethical issues of CRISPR technology and gene editing through the lens of solidarity","year":2017,"lang":"en","type":"review","venue":"British Medical Bulletin","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre; McGill Genome Centre; Dalhousie University","funders":"","keywords":"CRISPR; Eugenics; Solidarity; Political science; Transhumanism; Engineering ethics; Biology; Environmental ethics; Genetics; Law; Gene; Engineering; Politics","score_opus":0.030517416341560747,"score_gpt":0.38794904450754575,"score_spread":0.357431628165985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2589897652","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008084944,0.9948781,0.0013445673,0.0025707586,0.00021499916,0.0002926826,0.00006559376,0.000011467334,0.00054096815],"genre_scores_gemma":[0.0012484224,0.99677974,0.0008410276,0.00011729398,0.0006946595,0.000044717,0.000056728695,0.00003354546,0.0001838822],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99830335,0.00011136506,0.00060126197,0.0003928436,0.00032413588,0.0002670128],"domain_scores_gemma":[0.9989389,0.00007708446,0.00028480001,0.0005314877,0.00009659112,0.0000711361],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00062931725,0.00022094815,0.0009880116,0.000038701306,0.00009773612,0.000022330829,0.00062018016,0.0015761598,0.000109780965],"category_scores_gemma":[0.0026022312,0.00019252028,0.0002293233,0.00006444848,0.00096142315,8.429427e-7,0.00055344845,0.0008541906,0.0000035068288],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034031086,0.000044122706,0.000005528692,0.005188496,0.00017439868,0.00004191,0.00002083993,3.601011e-7,0.00013808183,0.0002545239,0.019098343,0.97503],"study_design_scores_gemma":[0.00016657068,0.00008069961,0.000006133935,0.004178122,0.00014102625,0.00050010055,0.000019073668,0.000001226252,0.00093723246,0.00006132551,0.99374294,0.00016557238],"about_ca_topic_score_codex":0.00014431194,"about_ca_topic_score_gemma":0.000037528218,"teacher_disagreement_score":0.9748644,"about_ca_system_score_codex":0.000004490562,"about_ca_system_score_gemma":0.00014469028,"threshold_uncertainty_score":0.99972},"labels":[],"label_agreement":null},{"id":"W2590143063","doi":"10.1038/ng.3793","title":"Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci","year":2017,"lang":"en","type":"article","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Biology; Genetics; Computational biology; Mutagenesis; Intergenic region; Cas9; MYB; Quantitative trait locus; Insertional mutagenesis; CRISPR; Genome; Gene; Mutation; Gene expression","score_opus":0.011847632126900706,"score_gpt":0.3017242933716994,"score_spread":0.2898766612447987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590143063","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99375236,0.003762506,0.0011426577,0.000035952653,0.0007607466,0.0002252493,0.000161532,0.000034371136,0.0001246378],"genre_scores_gemma":[0.995615,0.000180922,0.0025322319,0.000121175515,0.0004972154,0.0000074730665,0.00024170945,0.00007654663,0.00072770513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983072,0.0000464267,0.00034139972,0.00054665544,0.0002966378,0.00046165727],"domain_scores_gemma":[0.9984874,0.000016671744,0.00027322565,0.0009164159,0.00016798082,0.00013828653],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019832877,0.00031502033,0.00023926614,0.00005219552,0.00078161753,0.00015454438,0.0004955633,0.0006610529,0.000034873756],"category_scores_gemma":[0.000374442,0.00033927025,0.00016656872,0.000054514734,0.00010069559,0.000008651141,0.00041917685,0.0002562368,0.000004704147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057262154,0.000064645414,0.03395271,0.000062831394,0.00026750183,0.00004585615,0.00012348406,0.0027749708,0.9555443,0.0000028934192,0.0024394465,0.0046640825],"study_design_scores_gemma":[0.0014512419,0.000107532695,0.25915664,0.00007014669,0.00018218665,0.00006508495,0.00015909587,0.010909503,0.7179237,0.000021325512,0.009194869,0.0007586782],"about_ca_topic_score_codex":0.000038604227,"about_ca_topic_score_gemma":0.0004748966,"teacher_disagreement_score":0.23762062,"about_ca_system_score_codex":0.00007215969,"about_ca_system_score_gemma":0.00006347893,"threshold_uncertainty_score":0.99990594},"labels":[],"label_agreement":null},{"id":"W2590381489","doi":"10.3390/diseases5010006","title":"A Prospective Treatment Option for Lysosomal Storage Diseases: CRISPR/Cas9 Gene Editing Technology for Mutation Correction in Induced Pluripotent Stem Cells","year":2017,"lang":"en","type":"review","venue":"Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"CRISPR; Genome editing; Induced pluripotent stem cell; Cas9; Biology; Computational biology; Genetic enhancement; Homology directed repair; Gene; Bioinformatics; Genetics; DNA repair; Embryonic stem cell; Nucleotide excision repair","score_opus":0.03128012698098827,"score_gpt":0.3653439993233172,"score_spread":0.3340638723423289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590381489","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0057918853,0.9675199,0.0192785,0.000010911899,0.0014498893,0.004478954,0.0014091383,0.000055753248,0.000005077282],"genre_scores_gemma":[0.08268303,0.90028554,0.0005074812,0.000007886467,0.0018904395,0.010369785,0.003762077,0.00016045042,0.00033333842],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984475,0.00003685099,0.00039364785,0.0006975713,0.000093211944,0.0003312328],"domain_scores_gemma":[0.9989869,0.000040087834,0.00032818667,0.00042553555,0.00011722126,0.00010209039],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004968879,0.00041810362,0.000712623,0.00022676065,0.00016362492,0.00005782843,0.00017552769,0.0003584202,0.0000011894659],"category_scores_gemma":[0.000106979875,0.00039192004,0.00047985977,0.0000892586,0.000034334258,0.000008467225,0.000054011492,0.00007567672,0.0000018291266],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013070267,0.0003325508,0.000121324054,0.0033980291,0.00028654604,0.000014727158,0.00003263458,0.0005517976,0.0018700105,0.00001270417,0.00013679157,0.9931122],"study_design_scores_gemma":[0.008900538,0.006454985,0.00093377515,0.008117908,0.008217623,0.00011682026,0.001112851,0.004767452,0.0719304,0.00023775718,0.8858511,0.0033587797],"about_ca_topic_score_codex":0.000011402286,"about_ca_topic_score_gemma":0.000027738775,"teacher_disagreement_score":0.9897534,"about_ca_system_score_codex":0.00025809093,"about_ca_system_score_gemma":0.00024314101,"threshold_uncertainty_score":0.99985325},"labels":[],"label_agreement":null},{"id":"W2590748603","doi":"10.1080/21645515.2017.1295191","title":"New approaches for characterization of the genetic stability of vaccine cell lines","year":2017,"lang":"en","type":"review","venue":"Human Vaccines & Immunotherapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Computational biology; Biology; Digital polymerase chain reaction; Cell culture; Polymerase chain reaction; DNA sequencing; Genetics; Virology; DNA; Gene","score_opus":0.0956123976189678,"score_gpt":0.35925949074801294,"score_spread":0.26364709312904516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590748603","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0063195825,0.9844819,0.0075576426,0.000010850327,0.0002917893,0.0011911711,0.00010845586,0.000007668556,0.0000309527],"genre_scores_gemma":[0.008645392,0.9887642,0.0008061798,0.000009314236,0.00047432305,0.000064139596,0.00036699077,0.00011174454,0.000757688],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984916,0.00005913424,0.0007933471,0.0003440334,0.00010518092,0.00020669348],"domain_scores_gemma":[0.99757546,0.000023010527,0.00086877105,0.0013965544,0.00010411916,0.00003206498],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015767662,0.00037987094,0.000908669,0.000054917058,0.00010651995,0.00002222384,0.0007834684,0.00032784106,0.000018017206],"category_scores_gemma":[0.000020649059,0.00027822217,0.0006053662,0.00007198145,0.000028410355,0.0000030813774,0.0001597809,0.00011414186,4.6669484e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005499275,0.00015658622,0.00029391926,0.017434672,0.00051484915,8.2671896e-8,0.0001156275,0.000020902658,0.20296171,0.00003662108,0.000058103426,0.77835196],"study_design_scores_gemma":[0.00078067265,0.00022103559,0.0016587758,0.0009477452,0.00087367627,0.000004948036,0.000007348294,0.000022227392,0.100192785,0.000027990689,0.8948634,0.00039935877],"about_ca_topic_score_codex":0.000010020796,"about_ca_topic_score_gemma":0.000015904714,"teacher_disagreement_score":0.8948053,"about_ca_system_score_codex":0.000012230465,"about_ca_system_score_gemma":0.00018503593,"threshold_uncertainty_score":0.999967},"labels":[],"label_agreement":null},{"id":"W2591652900","doi":"10.1038/protex.2017.026","title":"Generation of FLIP and FLIP-FlpE targeting vectors for conditional and reversible gene knockouts","year":2017,"lang":"en","type":"article","venue":"Protocol Exchange","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"L'Alliance Boviteq","funders":"","keywords":"Flip; Gene knockout; Computational biology; Conditional gene knockout; Gene; Genetics; Biology; Computer science; Cell biology; Phenotype","score_opus":0.04099159183153085,"score_gpt":0.3625465830521922,"score_spread":0.32155499122066133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2591652900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7981739,0.0009829733,0.06272727,0.00039316068,0.00025842056,0.13641566,0.00032852477,0.000027986267,0.00069212104],"genre_scores_gemma":[0.907703,0.000045255943,0.009141955,0.000047973357,0.00082865084,0.081538364,0.00017254661,0.000025506448,0.00049679057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995385,0.0000087095,0.000106668245,0.00018332459,0.000051283307,0.00011154412],"domain_scores_gemma":[0.9996676,0.000004663379,0.00007847018,0.00014745002,0.000059210353,0.000042595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013103017,0.00008327699,0.00008877217,0.000021446016,0.00015163599,0.000026802847,0.000062123916,0.000069943875,0.000014462329],"category_scores_gemma":[0.0000745858,0.00008410137,0.000025749043,0.000009297787,0.000041131778,0.0000058749915,0.00007897128,0.000023688448,2.6311892e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041464165,0.0000137467705,0.0023745298,0.0001754217,0.000018797615,3.1692562e-7,0.00005786043,0.000028114317,0.9922866,0.00002865742,0.002643249,0.0023312215],"study_design_scores_gemma":[0.0009878291,0.00021679509,0.003451164,0.000013746296,0.000010030387,0.0000038017392,0.000013307576,0.00095225265,0.94550323,0.00005483762,0.048668973,0.00012402267],"about_ca_topic_score_codex":0.000009012172,"about_ca_topic_score_gemma":0.000012061275,"teacher_disagreement_score":0.10952907,"about_ca_system_score_codex":0.0000038266253,"about_ca_system_score_gemma":0.000014166767,"threshold_uncertainty_score":0.34295544},"labels":[],"label_agreement":null},{"id":"W2592336675","doi":"10.1242/dmm.026765","title":"A rapid and effective method for screening, sequencing and reporter verification of engineered frameshift mutations in zebrafish","year":2017,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Terry Fox Research Institute; Canadian Institutes of Health Research; Dalhousie University","keywords":"Frameshift mutation; Biology; CRISPR; Genetics; Zebrafish; Cas9; Gene; Genome editing; Mutant; Mutation; Exon; Genetic screen; Computational biology","score_opus":0.017522943414378715,"score_gpt":0.3165613096682174,"score_spread":0.29903836625383867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592336675","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31128818,0.00032737735,0.6879587,0.00003193801,0.000023459681,0.00031275532,0.000037370835,0.000004724193,0.000015459224],"genre_scores_gemma":[0.924377,0.00003332756,0.07531375,0.000022610753,0.000021012293,0.00014426291,0.000063106,0.000014853034,0.000010065242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994155,0.000019079502,0.00014001793,0.00025825144,0.000056645986,0.00011046923],"domain_scores_gemma":[0.99950117,0.00001771835,0.00007642894,0.00027716224,0.000048448546,0.00007910172],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021756715,0.0000962632,0.00011871164,0.000041689374,0.00006869161,0.000026100985,0.0000622298,0.00006365589,9.213578e-7],"category_scores_gemma":[0.0001430186,0.000103460516,0.000040236693,0.000015573192,0.000022827375,0.000010428095,0.00004165037,0.000031183397,2.6676693e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013976815,0.000027513302,0.0001453287,0.00016157528,0.00006115478,0.0000042615643,0.00040337,0.011448989,0.965927,0.0035668048,0.000010338189,0.018103916],"study_design_scores_gemma":[0.0012084561,0.00016177732,0.010900779,0.00007212522,0.000102327205,0.0000058228065,0.0001507376,0.48004505,0.48685148,0.020181837,0.00006438994,0.00025521353],"about_ca_topic_score_codex":0.000021847485,"about_ca_topic_score_gemma":0.000009400182,"teacher_disagreement_score":0.61308885,"about_ca_system_score_codex":0.0000055699015,"about_ca_system_score_gemma":0.000023615894,"threshold_uncertainty_score":0.42189974},"labels":[],"label_agreement":null},{"id":"W2593551397","doi":"10.7554/elife.21666","title":"A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress","year":2017,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Human Frontier Science Program; Darwin Trust of Edinburgh; Cancer Research UK; Wellcome Trust","keywords":"Heterochromatin; Biology; Heterochromatin protein 1; Piwi-interacting RNA; Genetics; Euchromatin; Chromatin; Germline; RNA interference; Epigenetics; Transposable element; Genome; Cell biology; Gene; RNA","score_opus":0.01253474694172283,"score_gpt":0.27865317021313657,"score_spread":0.2661184232714137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2593551397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977461,0.00019525523,0.0013676316,0.000024325003,0.00004187878,0.00015207424,0.00015310041,0.000005127225,0.00031450915],"genre_scores_gemma":[0.99760824,0.000062429346,0.002097007,0.000033830012,0.000049134258,0.000009752742,0.000040301307,0.000013786388,0.000085505366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994516,0.00000953543,0.00013341384,0.00019145351,0.000083790655,0.00013024667],"domain_scores_gemma":[0.99941707,0.0000061544115,0.00008680053,0.00031442472,0.00009386346,0.00008171548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005604278,0.00011127577,0.00013083793,0.000019607916,0.00007402373,0.000027957769,0.00012355848,0.000045689765,0.000004148962],"category_scores_gemma":[0.00007846665,0.000091950606,0.00001814315,0.000020932404,0.000042159303,0.0000021447042,0.00011225243,0.000031149186,6.868076e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041278527,0.000032898304,0.03402159,0.000037076163,0.000049193724,0.000002044533,0.0002256729,0.000103165294,0.9647231,0.000009813056,0.00014695157,0.00060723285],"study_design_scores_gemma":[0.00038995073,0.00039231192,0.08987029,0.000052251322,0.000010003182,0.0000013779039,0.0001937403,0.00002923147,0.90809995,0.0000013094826,0.0008460137,0.00011356341],"about_ca_topic_score_codex":0.000023783407,"about_ca_topic_score_gemma":0.00021045667,"teacher_disagreement_score":0.056623124,"about_ca_system_score_codex":0.0000039150686,"about_ca_system_score_gemma":0.000022681148,"threshold_uncertainty_score":0.3749637},"labels":[],"label_agreement":null},{"id":"W2598322167","doi":"10.3389/fmicb.2017.00461","title":"Predictive Modeling of a Batch Filter Mating Process","year":2017,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Canada Foundation for Innovation","keywords":"Identifiability; Computer science; Biological system; Filter (signal processing); Extrapolation; Plasmid; Process (computing); Biochemical engineering; Mathematics; Machine learning; Biology; Statistics; Engineering; Gene; Genetics","score_opus":0.006569573616172563,"score_gpt":0.27767286097428073,"score_spread":0.2711032873581082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2598322167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8157268,0.0006347588,0.18255717,0.00003135538,0.0003887948,0.000106678424,0.000024221696,0.0000043379437,0.0005258509],"genre_scores_gemma":[0.99059117,0.0000574459,0.009105145,0.000022470382,0.000075400836,0.000012712383,0.00004122388,0.000012591721,0.00008186654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993611,0.000018301727,0.00018186915,0.00022641517,0.00001933414,0.00019297138],"domain_scores_gemma":[0.99954015,0.0000025012005,0.000080410246,0.00031243893,0.000042938107,0.000021559312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116708674,0.00009918372,0.00016812496,0.000044977874,0.000059594568,0.000008121251,0.00027755948,0.00014555924,0.000004414735],"category_scores_gemma":[0.00007996784,0.00009952444,0.00004369378,0.000018763156,0.00009562294,0.00000318847,0.00010113569,0.00008095991,6.562257e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008536845,0.000026336693,0.040705405,0.0000614678,0.000052428346,0.0000018782846,0.00027023008,0.02370062,0.93295974,0.0000035429027,0.0010081887,0.0011247834],"study_design_scores_gemma":[0.0015442923,0.0003300968,0.0033401668,0.00013065047,0.000029991235,0.000039075072,0.0009331714,0.1079703,0.8834094,0.0004675649,0.0013550498,0.00045026667],"about_ca_topic_score_codex":0.000013819388,"about_ca_topic_score_gemma":0.000012110787,"teacher_disagreement_score":0.1748643,"about_ca_system_score_codex":0.000007980231,"about_ca_system_score_gemma":0.000026159621,"threshold_uncertainty_score":0.4058489},"labels":[],"label_agreement":null},{"id":"W2601226883","doi":"10.1016/j.cell.2017.03.012","title":"Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex","year":2017,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":231,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Office of Experimental Program to Stimulate Competitive Research; Montana State University; National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; NIH Office of the Director; University of California, San Francisco; M.J. Murdock Charitable Trust; National Institutes of Health; Canadian Institutes of Health Research; Sandler Foundation; University of California; Amgen","keywords":"Trans-activating crRNA; Biology; CRISPR; Nuclease; RNA; Immune system; Computational biology; Genetics; Cas9; DNA; Cell biology; Gene","score_opus":0.018974687271636273,"score_gpt":0.3058475079350208,"score_spread":0.28687282066338454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2601226883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738005,0.00020297924,0.022804279,0.000070184935,0.00031075106,0.00013125423,0.00008940238,0.000010218679,0.002580425],"genre_scores_gemma":[0.9965256,0.00004668782,0.002363093,0.000057721507,0.00009561821,0.0000030486804,0.000071045906,0.00002204957,0.0008151417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992727,0.000024497444,0.00016011512,0.0002461957,0.00009767861,0.00019880726],"domain_scores_gemma":[0.99907476,0.000005893709,0.00012381199,0.00069745677,0.0000385819,0.0000595112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086158536,0.0001449795,0.00018509978,0.00002053321,0.0000787214,0.000031370717,0.0004151756,0.000119033284,0.00009016369],"category_scores_gemma":[0.000039791128,0.00013757746,0.00008825368,0.000012170332,0.00006283192,0.0000029874093,0.00018965946,0.00006900736,0.000003493348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016474021,0.000010789205,0.000901544,0.0000433101,0.00001593261,0.0000016781951,0.000046526904,0.00010419681,0.9944067,0.000030133244,0.0042197974,0.00020290291],"study_design_scores_gemma":[0.000394561,0.00007834384,0.0184374,0.000010071028,0.000007914784,0.0000053192907,0.000040656905,0.00012868721,0.9781321,0.00044376164,0.0021630274,0.0001581256],"about_ca_topic_score_codex":0.000028464394,"about_ca_topic_score_gemma":0.000033088872,"teacher_disagreement_score":0.022725087,"about_ca_system_score_codex":0.000005096165,"about_ca_system_score_gemma":0.000014396724,"threshold_uncertainty_score":0.5610246},"labels":[],"label_agreement":null},{"id":"W2604034495","doi":"10.1101/116251","title":"A marker-free co-selection strategy for high efficiency human genome engineering","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Université Laval; Héma-Québec; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Genome editing; CRISPR; Genome engineering; Biology; Cas9; Computational biology; Genetics; Gene","score_opus":0.01102794308620109,"score_gpt":0.2627472356845057,"score_spread":0.2517192925983046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604034495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8801291,0.0016518754,0.11566976,0.000032224987,0.0008420028,0.0010139213,0.0004537395,0.00018575067,0.000021616635],"genre_scores_gemma":[0.99246705,0.00015417316,0.005450353,0.000022182669,0.0013234059,0.0003589823,0.000008811035,0.00018307327,0.000031969226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99759495,0.000030218862,0.00043476833,0.0010598187,0.00022082208,0.0006594064],"domain_scores_gemma":[0.9974782,0.000015156133,0.0002770643,0.0017181898,0.00029791764,0.00021346808],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004472928,0.00059307466,0.00044889466,0.00017581224,0.00030586735,0.00025398677,0.0009849931,0.00069748197,0.00001621982],"category_scores_gemma":[0.00021318806,0.00071214465,0.0002191968,0.000090532376,0.00006609793,0.000008747817,0.00043684215,0.00041076553,0.0000066311836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027600561,0.00005867402,0.000397682,0.00039076732,0.0001547818,0.0000049047503,0.0000017169043,0.00965538,0.9888225,0.0002147132,0.0002688521,0.0000023876835],"study_design_scores_gemma":[0.001033112,0.00031515452,0.061091363,0.00013540151,0.00012800668,7.8140246e-8,0.0000011322055,0.0018980055,0.925135,0.000004525157,0.009074327,0.0011839046],"about_ca_topic_score_codex":0.00003660642,"about_ca_topic_score_gemma":0.0000055833766,"teacher_disagreement_score":0.11233794,"about_ca_system_score_codex":0.00009894108,"about_ca_system_score_gemma":0.00027129878,"threshold_uncertainty_score":0.99953294},"labels":[],"label_agreement":null},{"id":"W2604236951","doi":"10.1158/1557-3125.dnarepair16-pr05","title":"Abstract PR05: Distinct BRCA1- and BRCA2-specific functions at stalled replication forks: Clinical implications for differences between BRCA1 and BRCA2 mutation-driven cancer","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"BRCA2 Protein; Biology; Mutation; Cancer research; DNA replication; DNA repair; Suppressor; Breast cancer; Gene; Cancer; Cell biology; Genetics; Germline mutation","score_opus":0.11948806297946768,"score_gpt":0.4822580194204909,"score_spread":0.3627699564410232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604236951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97490597,0.0051070964,0.01482324,0.0035059599,0.000099690835,0.0009139915,0.00040691672,0.000017755483,0.00021938197],"genre_scores_gemma":[0.9944004,0.003014712,0.0004170892,0.000029435672,0.00039831726,0.0009927187,0.000260418,0.000042805048,0.00044410396],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99808013,0.00006405125,0.0003495573,0.000883775,0.00021189856,0.00041059678],"domain_scores_gemma":[0.998169,0.00012119847,0.0001397627,0.0010344358,0.0003174589,0.00021813587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005688453,0.00018727912,0.00023807379,0.000071240036,0.0008741545,0.00020230768,0.00034598235,0.00019960705,0.000025606734],"category_scores_gemma":[0.0003083355,0.00018416386,0.00009876073,0.00006837673,0.00037301413,0.000014257881,0.00031701336,0.0002197572,0.0000026376063],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020323828,0.000085319814,0.34703922,0.0001731503,0.00039617994,0.0000034881677,0.00013649305,0.00013635031,0.51935154,0.00021858614,0.0046862545,0.1275702],"study_design_scores_gemma":[0.0009874345,0.0001794272,0.9492944,0.000046211906,0.000045115572,0.0000043281043,0.00004117336,0.00020383304,0.024376022,0.00033883244,0.024229886,0.00025331957],"about_ca_topic_score_codex":0.0003110953,"about_ca_topic_score_gemma":0.0008064658,"teacher_disagreement_score":0.60225517,"about_ca_system_score_codex":0.00007204229,"about_ca_system_score_gemma":0.00013220418,"threshold_uncertainty_score":0.75099844},"labels":[],"label_agreement":null},{"id":"W2604376600","doi":"10.3389/fgene.2017.00040","title":"Disease Resistance and the Definition of Genetic Enhancement","year":2017,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"Canadian Institutes of Health Research","keywords":"Disease; Context (archaeology); Genome editing; Resistance (ecology); Affect (linguistics); Public health; Psychological intervention; Mechanism (biology); CRISPR; Internet privacy; Medicine; Psychology; Biology; Genetics; Computer science; Gene; Psychiatry; Communication","score_opus":0.0067633164054214465,"score_gpt":0.25596271196648296,"score_spread":0.24919939556106152,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604376600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84681326,0.032372683,0.11833173,0.0002943209,0.0004617595,0.00028473462,0.000014184378,0.0000027415385,0.0014246147],"genre_scores_gemma":[0.9608156,0.0064034406,0.03243151,0.000039263712,0.000063766776,0.000022425744,0.0000071516733,0.0000103531,0.00020648932],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99942386,0.000024508694,0.00016444686,0.00017303658,0.000085867905,0.00012826864],"domain_scores_gemma":[0.99932843,0.0000051467327,0.00008058529,0.0005149938,0.00002613594,0.000044729928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120548444,0.00008686077,0.00010958883,0.00002197116,0.00008474058,0.000021807808,0.00020726063,0.000042848696,0.0000018123153],"category_scores_gemma":[0.00007979293,0.00007337616,0.00003582916,0.000017533343,0.00026071785,0.0000013651302,0.000101326244,0.00004055262,3.0570732e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028590446,0.00024510192,0.809982,0.0006564997,0.00029670942,0.00002431247,0.0008941465,0.0027311635,0.11624507,0.0030203406,0.01730012,0.04574548],"study_design_scores_gemma":[0.005719018,0.00015208614,0.82637316,0.00013438106,0.00012858733,0.0000030503297,0.00020658034,0.0026877117,0.1255175,0.014741712,0.023792151,0.0005440322],"about_ca_topic_score_codex":0.0000041488524,"about_ca_topic_score_gemma":0.00002563726,"teacher_disagreement_score":0.11400237,"about_ca_system_score_codex":0.0000052837504,"about_ca_system_score_gemma":0.000022882794,"threshold_uncertainty_score":0.2992193},"labels":[],"label_agreement":null},{"id":"W2604383012","doi":"10.1158/1557-3125.dnarepair16-a23","title":"Abstract A23: BRCA1 mutations in the BRCT domain can be removed through alternative splicing and induce PARP inhibitor resistance","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Exon; Biology; Molecular biology; Olaparib; Immunoprecipitation; Mutation; Cancer research; Gene; Genetics; Poly ADP ribose polymerase; Polymerase","score_opus":0.04777240708747944,"score_gpt":0.42084901607713926,"score_spread":0.37307660898965983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604383012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99032104,0.0022739025,0.0007454316,0.0034992346,0.00006982264,0.00035031984,0.0000333481,0.000004590337,0.0027023195],"genre_scores_gemma":[0.99824524,0.0005043865,0.00048947847,0.00021629593,0.00017846988,0.00013038194,0.000020576452,0.000026302638,0.00018889744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850893,0.00011997459,0.0001710752,0.00042122454,0.00037480408,0.00040396914],"domain_scores_gemma":[0.9990501,0.000038447728,0.00005849071,0.00068086386,0.0001094222,0.000062697225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006994693,0.00014077827,0.00012407753,0.00005509086,0.00038914933,0.00017245594,0.00047491762,0.000100162484,0.00000668589],"category_scores_gemma":[0.00022440714,0.00012250834,0.00004413572,0.00010720095,0.00024211979,0.000009300595,0.00019109152,0.00036062623,0.0000010344628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049564496,0.000029450532,0.001036847,0.00004138656,0.00003567428,0.00008930095,0.0012926838,0.00024565708,0.9953656,0.00037791595,0.00038930992,0.0010465772],"study_design_scores_gemma":[0.0011460643,0.000069485584,0.06484699,0.00014550773,0.000009263835,0.000010327349,0.0010988816,0.00003812643,0.91801935,0.0017654785,0.012565886,0.00028461558],"about_ca_topic_score_codex":0.0026340208,"about_ca_topic_score_gemma":0.005184762,"teacher_disagreement_score":0.07734626,"about_ca_system_score_codex":0.000052326315,"about_ca_system_score_gemma":0.00012464513,"threshold_uncertainty_score":0.4995745},"labels":[],"label_agreement":null},{"id":"W2604874086","doi":"10.1158/1557-3125.dnarepair16-pr15","title":"Abstract PR15: Cas9/RNA-based forward genetic screenings in mouse embryonic stem cells uncovered the role of genes mediating resistance to ATR inhibitors","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Biology; Cas9; Embryonic stem cell; Genome editing; Doxycycline; Gene knockout; Gene; Guide RNA; Cell biology; Computational biology; Genetics","score_opus":0.017837505474910337,"score_gpt":0.3431429405597196,"score_spread":0.32530543508480925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604874086","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988513,0.0090619335,0.000994328,0.0003861223,0.00008722775,0.0005845821,0.00005343863,0.000007391972,0.0003119653],"genre_scores_gemma":[0.99798673,0.0002278967,0.00091449136,0.00004889812,0.00014587172,0.00017804475,0.00000776541,0.000056371642,0.00043394757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782413,0.00010851145,0.00032575647,0.0005083611,0.0006263347,0.00060692395],"domain_scores_gemma":[0.9983569,0.000043238986,0.00013054919,0.0010856692,0.00023048963,0.00015319648],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077895593,0.0002039422,0.00021980249,0.00013585764,0.0002376633,0.00009820801,0.00085055624,0.00014906909,0.000009791958],"category_scores_gemma":[0.00012910338,0.00018323692,0.00012267088,0.00018157781,0.00015700015,0.000006441644,0.00032316573,0.0002933882,0.0000049596397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013339975,0.000021853391,0.0041432437,0.00008561254,0.0000329282,0.000017999202,0.00009778718,0.021346463,0.96741366,0.0000062797208,0.00025165663,0.006449141],"study_design_scores_gemma":[0.00048013218,0.00009779359,0.004218454,0.000093588824,0.0000077983295,5.191744e-7,0.00017744409,0.00039241038,0.9886792,0.000017244009,0.0056359153,0.00019951431],"about_ca_topic_score_codex":0.0011698065,"about_ca_topic_score_gemma":0.002446607,"teacher_disagreement_score":0.02126555,"about_ca_system_score_codex":0.00008205241,"about_ca_system_score_gemma":0.00032330243,"threshold_uncertainty_score":0.74721843},"labels":[],"label_agreement":null},{"id":"W2605234400","doi":"10.1158/1557-3125.dnarepair16-ia21","title":"Abstract IA21: Targeting WEE1 kinase to potentiate chemoradiation in the treatment of pancreatic cancer","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Gemcitabine; Pancreatic cancer; Wee1; Cancer research; Cancer; Medicine; Colorectal cancer; Oncology; DNA damage; Radiation therapy; G2-M DNA damage checkpoint; Internal medicine; Cell cycle checkpoint; Cell cycle; Biology; Cyclin-dependent kinase 1","score_opus":0.03530080655290229,"score_gpt":0.41976400178458323,"score_spread":0.38446319523168093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605234400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99167687,0.0061551416,0.0003587624,0.000895326,0.00007651086,0.0004169609,0.00002079999,0.0000027690824,0.0003968631],"genre_scores_gemma":[0.9970505,0.0021160147,0.00014860628,0.00004447181,0.00014898855,0.00033283568,0.00001917288,0.000020294756,0.00011911951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988658,0.000057656463,0.00016484676,0.00027875378,0.00029310654,0.00033985332],"domain_scores_gemma":[0.9991952,0.000012560128,0.000050928465,0.00057147746,0.00010347962,0.000066331464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004015807,0.00011512223,0.00013521191,0.00007557102,0.00014658833,0.00006068275,0.00035892645,0.00006649719,0.000027660597],"category_scores_gemma":[0.00009560507,0.00009135352,0.000071492,0.00010151592,0.000056670546,0.000003766239,0.00005988643,0.000088153516,0.000003814984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062279214,0.00007913812,0.0045990604,0.000041414445,0.000041090756,0.000022892902,0.0003147092,0.004025569,0.9759141,0.00000975962,0.0002551364,0.014634834],"study_design_scores_gemma":[0.00053805654,0.00021100727,0.06549019,0.000044367218,0.0000135228365,7.295834e-7,0.00012369944,0.00017414946,0.9253623,0.000020241258,0.007904889,0.00011684312],"about_ca_topic_score_codex":0.003844808,"about_ca_topic_score_gemma":0.00067248184,"teacher_disagreement_score":0.06089113,"about_ca_system_score_codex":0.00006964157,"about_ca_system_score_gemma":0.00009965548,"threshold_uncertainty_score":0.58122253},"labels":[],"label_agreement":null},{"id":"W2605240021","doi":"10.1158/1557-3125.dnarepair16-ia09","title":"Abstract IA09: Replication fork stability confers chemoresistance in BRCA-deficient cells","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"PARP1; Cisplatin; Poly ADP ribose polymerase; DNA replication; Homologous recombination; Biology; DNA repair; DNA damage; Cancer research; Polymerase; Molecular biology; DNA; Genetics; Chemotherapy","score_opus":0.0540417647408808,"score_gpt":0.4349319384568168,"score_spread":0.38089017371593603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605240021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921887,0.0017027966,0.0015831112,0.00047830614,0.00010285097,0.00039457742,0.000019438276,0.000008581169,0.0035216524],"genre_scores_gemma":[0.99895525,0.0003764119,0.00018060562,0.000041899555,0.00006959516,0.00016677116,0.000022202868,0.000027053042,0.00016022481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982662,0.000047822716,0.00020364227,0.00064918166,0.00036569734,0.00046740894],"domain_scores_gemma":[0.9978846,0.000012219078,0.000058815218,0.0017530409,0.00018636363,0.00010498382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00099675,0.0001259943,0.0001334082,0.000062436295,0.0001928397,0.00010474123,0.0005411184,0.00012470916,0.000038017817],"category_scores_gemma":[0.00024628063,0.00014078812,0.00007087828,0.00008824024,0.0001860038,0.000005154663,0.0002171561,0.00024564375,0.0000097225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000726933,0.000047286165,0.0030477324,0.000064252636,0.000012202961,0.000011103832,0.000046316352,0.00059788156,0.99160165,0.0000656197,0.0003501245,0.004083155],"study_design_scores_gemma":[0.0003783245,0.00004126065,0.058151297,0.00003264219,0.0000025705597,7.28984e-7,0.000051155963,0.000121760015,0.93346524,0.00006189052,0.0075439946,0.00014912189],"about_ca_topic_score_codex":0.0006651022,"about_ca_topic_score_gemma":0.0007209584,"teacher_disagreement_score":0.058136377,"about_ca_system_score_codex":0.00010079147,"about_ca_system_score_gemma":0.0001717493,"threshold_uncertainty_score":0.5741173},"labels":[],"label_agreement":null},{"id":"W2605294424","doi":"10.1177/0840470416689313","title":"The ethics of genome editing in the clinic: A dose of realism for healthcare leaders","year":2017,"lang":"en","type":"review","venue":"Healthcare Management Forum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Timeline; Genome editing; Health care; Translational research; Engineering ethics; Ethical issues; Genome; Medicine; Political science; Biology; Genetics; Engineering","score_opus":0.1661568409373097,"score_gpt":0.4944614077458528,"score_spread":0.3283045668085431,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605294424","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000052766345,0.9869823,0.0006526334,0.008890779,0.00048811568,0.0024637533,0.00017394015,0.000005566983,0.00033765542],"genre_scores_gemma":[0.0017071421,0.99614525,0.00030423098,0.00036650684,0.00030242477,0.0004233617,0.0003760267,0.00004941029,0.00032564267],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99750143,0.00029588817,0.000998873,0.00040609582,0.00026576887,0.00053193094],"domain_scores_gemma":[0.9976692,0.00021491642,0.00072466535,0.0012170414,0.00011991992,0.000054260145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025430783,0.00028961312,0.0007476034,0.0000955999,0.00028940485,0.000024569781,0.0009594851,0.00044408883,7.846828e-7],"category_scores_gemma":[0.00020908429,0.00019188301,0.000449067,0.00010735725,0.00015714743,0.0000022075849,0.00026731734,0.0005052909,9.085996e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003067268,0.000030414347,0.000016368254,0.07427928,0.00019531138,0.000003753056,0.00045728192,0.000011066783,0.0000017119781,0.0027830047,0.0020449993,0.92014617],"study_design_scores_gemma":[0.0002246042,0.0002397847,0.00003291486,0.0027981123,0.00010789676,0.0000042920888,0.0025873182,0.000004989655,0.0000036318897,0.00015096668,0.9936885,0.00015697694],"about_ca_topic_score_codex":0.00020539785,"about_ca_topic_score_gemma":0.001364029,"teacher_disagreement_score":0.9916435,"about_ca_system_score_codex":0.000031441887,"about_ca_system_score_gemma":0.00019557466,"threshold_uncertainty_score":0.7824762},"labels":[],"label_agreement":null},{"id":"W2605538093","doi":"10.1139/cjm-2017-0067","title":"Three new active members of the I-OnuI family of homing endonucleases","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Islamic Development Bank","keywords":"Homing endonuclease; Endonuclease; Cleave; Biology; Genetics; Restriction enzyme; Computational biology; Intron; Homing (biology); DNA; Gene","score_opus":0.010296324694867772,"score_gpt":0.24813884456256127,"score_spread":0.2378425198676935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605538093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99649346,0.0018355658,0.0005187409,0.00019887637,0.00046976123,0.000049960625,0.000051136903,3.770303e-7,0.0003821003],"genre_scores_gemma":[0.9992861,0.00005224832,0.0003881528,0.00005952854,0.00013610932,1.9745092e-7,0.0000024716296,0.000008990751,0.00006619093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999501,0.000017030157,0.00021533109,0.000082774604,0.000022086924,0.00016176229],"domain_scores_gemma":[0.9991434,0.00001101806,0.00031789925,0.00029766487,0.00009908581,0.00013091396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088836285,0.00008145125,0.00017582458,0.00004950464,0.00007618588,0.0000069693197,0.0004761935,0.00010147514,0.000024521501],"category_scores_gemma":[0.00016972578,0.00006310555,0.00013916483,0.00002003745,0.00021401848,0.0000029622959,0.000043855278,0.00009369993,4.2698548e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024029392,0.0000033794875,0.0051738955,0.0000072590024,0.000084068924,0.0000038031258,0.000075725315,0.00013012497,0.9884925,0.000021514097,0.0028145344,0.003169176],"study_design_scores_gemma":[0.0005174147,0.00017561289,0.0466675,0.000052647418,0.00004234232,0.0001804269,0.00014053372,0.0000026645325,0.92220265,0.0000496453,0.02987886,0.00008968086],"about_ca_topic_score_codex":0.0032103069,"about_ca_topic_score_gemma":0.026722515,"teacher_disagreement_score":0.06628982,"about_ca_system_score_codex":0.000015128268,"about_ca_system_score_gemma":0.0006403527,"threshold_uncertainty_score":0.99103725},"labels":[],"label_agreement":null},{"id":"W2605666315","doi":"","title":"Establishment of hypersensitive transposon trap vector system for isolating transcriptionally stimulated cells and genes","year":2016,"lang":"en","type":"article","venue":"The Molecular Biology Society of Japan","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sciencetech (Canada)","funders":"","keywords":"Transposable element; Trap (plumbing); Gene; Biology; Vector (molecular biology); Cell biology; Genetics; Genome; Physics; Recombinant DNA","score_opus":0.007383299791315255,"score_gpt":0.2571315309323815,"score_spread":0.24974823114106626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605666315","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8345112,0.0015153175,0.16325983,0.00023759068,0.000064399275,0.0002579801,0.00013170061,0.0000077512095,0.00001418153],"genre_scores_gemma":[0.9945376,0.00017504914,0.005126578,0.000042891537,0.000038381742,0.000014239167,0.000029128512,0.00001683392,0.00001929233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992927,0.00004647603,0.00021759547,0.0002211047,0.000052071202,0.00017006301],"domain_scores_gemma":[0.9995834,0.00004668285,0.00007549094,0.00016825469,0.000092361624,0.00003377674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001918494,0.00013086779,0.00019446888,0.000013269626,0.00004742734,0.0000027218396,0.000102378246,0.00014664493,0.0000015027571],"category_scores_gemma":[0.000008529719,0.00008692475,0.00021155213,0.000039241502,0.00020168393,0.0000018365185,0.00001849101,0.000032783108,1.0829443e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007044978,0.000016954053,0.00019129313,0.0000925751,0.00020806426,6.276548e-8,0.00029635412,0.00028255838,0.99634933,0.00023763909,0.000012265809,0.0022424455],"study_design_scores_gemma":[0.0008500136,0.000388179,0.00062376494,0.00004391511,0.00007567978,0.000005169198,0.0004250398,0.00054720143,0.9965803,0.000028261864,0.00031924513,0.00011320247],"about_ca_topic_score_codex":0.000014621812,"about_ca_topic_score_gemma":0.000003073177,"teacher_disagreement_score":0.16002636,"about_ca_system_score_codex":0.00000820001,"about_ca_system_score_gemma":0.000025486604,"threshold_uncertainty_score":0.35446885},"labels":[],"label_agreement":null},{"id":"W2605682686","doi":"10.21769/bioprotoc.2222","title":"Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9","year":2017,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"Canadian Institutes of Health Research; Universität Zürich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Gene knockout; CRISPR; Cell sorting; Cas9; Biology; Computational biology; Transduction (biophysics); Cell culture; Gene knockin; Genome editing; Gene; Cell biology; Cell; Genetics","score_opus":0.04573708340868193,"score_gpt":0.35850729909546897,"score_spread":0.31277021568678703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605682686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.888658,0.00007826851,0.016738847,0.000011142269,0.00018338027,0.094268605,0.000029016905,0.000014036548,0.000018711313],"genre_scores_gemma":[0.9010454,0.000004431254,0.019594686,0.000020860984,0.00020931863,0.07900474,0.00002363357,0.000036819856,0.00006010061],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882984,0.00003496817,0.000343274,0.0004072075,0.0001265867,0.00025810188],"domain_scores_gemma":[0.9989393,0.0000039398574,0.00024938435,0.00055560516,0.00015185605,0.000099914934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009566489,0.0002320741,0.00019993745,0.00005661031,0.00025126006,0.00006605248,0.00019183088,0.0001799733,0.00000912972],"category_scores_gemma":[0.00006571854,0.000218302,0.000092862516,0.00003454109,0.00011237136,0.0000046000227,0.00023611604,0.0000626219,0.0000020723576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069862974,0.00020010059,0.0011844588,0.00010250772,0.00002211981,0.0000021830758,0.00009875507,0.0033950242,0.992316,4.3632664e-7,0.000055691853,0.0025528679],"study_design_scores_gemma":[0.0026923039,0.00023965524,0.0043374435,0.000024582663,0.000019583364,0.0000049967853,0.00003914057,0.04303433,0.94643116,2.100999e-7,0.0029330594,0.00024354353],"about_ca_topic_score_codex":0.00006759329,"about_ca_topic_score_gemma":0.00003920033,"teacher_disagreement_score":0.045884844,"about_ca_system_score_codex":0.00001225441,"about_ca_system_score_gemma":0.000044670804,"threshold_uncertainty_score":0.8902097},"labels":[],"label_agreement":null},{"id":"W2606620317","doi":"10.1038/s41598-017-01170-z","title":"Enhancing the throughput and multiplexing capabilities of next generation sequencing for efficient implementation of pooled shRNA and CRISPR screens","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Prostate Cancer Canada; Cancer Research Society; Movember Foundation","keywords":"CRISPR; Computational biology; DNA sequencing; Multiplex; Multiplexing; Small hairpin RNA; Computer science; Heteroduplex; Throughput; Biology; DNA; Genetics; Gene; Telecommunications; RNA; Wireless","score_opus":0.034236726823000406,"score_gpt":0.33814868887573224,"score_spread":0.30391196205273185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606620317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711449,0.0005774002,0.027425839,0.000035130262,0.0004949802,0.00029274359,0.0000073499496,0.000002477206,0.000019151421],"genre_scores_gemma":[0.9972255,0.000015799214,0.0025963925,0.000004760812,0.0000668922,0.000013960855,0.0000276342,0.0000065062527,0.000042547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991978,0.000012489337,0.00029246134,0.00027550163,0.00010633616,0.0001154135],"domain_scores_gemma":[0.9991797,0.000014481914,0.00024115935,0.00040966872,0.00013054784,0.00002443063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008189924,0.00007041627,0.000096600765,0.000026003558,0.00034527289,0.000093150964,0.00005741211,0.00003245773,0.0000017349862],"category_scores_gemma":[0.00018985519,0.00005648476,0.000036857346,0.0000198109,0.00019867718,0.000008204343,0.00007980034,0.000020179388,1.686632e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029350479,0.000003406664,0.0019991423,0.000055976878,0.000013632996,4.214268e-7,0.0007379621,0.000915905,0.9944429,0.000027839074,0.000042986852,0.0017568883],"study_design_scores_gemma":[0.00013449971,0.00004044111,0.0031450994,0.000018338495,0.000021436581,0.000016150381,0.0018362827,0.004162894,0.9902752,0.00008847527,0.00019960178,0.00006155778],"about_ca_topic_score_codex":0.00024258053,"about_ca_topic_score_gemma":0.00044870493,"teacher_disagreement_score":0.026080579,"about_ca_system_score_codex":0.0000073524093,"about_ca_system_score_gemma":0.000054365664,"threshold_uncertainty_score":0.2655595},"labels":[],"label_agreement":null},{"id":"W2607021366","doi":"10.1038/nmeth.4265","title":"Marker-free coselection for CRISPR-driven genome editing in human cells","year":2017,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Université Laval; Héma-Québec; Centre hospitalier universitaire de Québec","funders":"","keywords":"CRISPR; Genome editing; Cas9; Biology; Computational biology; Genome engineering; Nuclease; Homology directed repair; DNA; Genetics; Cell biology; DNA repair; Gene; Nucleotide excision repair","score_opus":0.012951897586686472,"score_gpt":0.41781107017819125,"score_spread":0.4048591725915048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607021366","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1847459,0.0020185087,0.80694336,0.00022199942,0.0018172569,0.0005262853,0.00003821502,0.00002727999,0.003661195],"genre_scores_gemma":[0.700374,0.000043599553,0.29754397,0.000085032225,0.0012061156,0.000043098153,0.0000468194,0.00003171976,0.0006256483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991762,0.000064110296,0.00015170372,0.00030249447,0.000065915025,0.00023954533],"domain_scores_gemma":[0.9991769,0.000027108465,0.000081953534,0.0006026906,0.00006456533,0.000046778227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065409177,0.0001299909,0.00014425533,0.000052003365,0.00019911736,0.000047993857,0.00038023887,0.0003862888,0.0000076031024],"category_scores_gemma":[0.0004555562,0.00013570861,0.00008702205,0.00003322331,0.00002886089,0.0000038264966,0.00013747046,0.0002762076,4.545847e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019132316,0.000013362109,0.00048698156,0.000031856656,0.000017860053,0.0000010048435,0.00001890596,0.00024505827,0.99050903,0.00005129352,0.0011777569,0.0074277553],"study_design_scores_gemma":[0.00063288806,0.0001020892,0.011602934,0.000012163305,0.00001546438,0.000003756389,0.000018847653,0.0007061201,0.90189636,0.0003370222,0.084496,0.00017637487],"about_ca_topic_score_codex":0.00001168124,"about_ca_topic_score_gemma":0.00007576409,"teacher_disagreement_score":0.5156281,"about_ca_system_score_codex":0.000018081133,"about_ca_system_score_gemma":0.000015890226,"threshold_uncertainty_score":0.5534037},"labels":[],"label_agreement":null},{"id":"W2607698473","doi":"10.1177/0840470417707091","title":"L’éthique de la modification du génome en clinique : une dose de réalisme pour les leaders en santé","year":2017,"lang":"fr","type":"review","venue":"Healthcare Management Forum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Political science; Humanities; Philosophy","score_opus":0.04397349414812718,"score_gpt":0.42348617260669735,"score_spread":0.3795126784585702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607698473","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007979547,0.859719,0.09613391,0.033606328,0.00061939127,0.0032319506,0.00014125269,0.00008146207,0.0056687654],"genre_scores_gemma":[0.096726485,0.89339364,0.004180618,0.00078562315,0.0009332818,0.000687455,0.0005718099,0.00012560218,0.0025955008],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960143,0.0011548357,0.0007846036,0.00084484194,0.00019589145,0.0010055271],"domain_scores_gemma":[0.9979218,0.00014514432,0.0004024829,0.0011473593,0.00008639708,0.00029680814],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0020011794,0.00062933157,0.0007866092,0.00017351692,0.00035042092,0.00011119811,0.0008241299,0.0014430638,0.000029736315],"category_scores_gemma":[0.00017609076,0.00068795076,0.0004776835,0.00011422982,0.00018608187,0.000008971043,0.00042771338,0.00078429806,0.000044426033],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033274304,0.00012397827,0.0011458345,0.024685023,0.00044397285,0.000099510755,0.0004725597,0.0005424099,0.00020338787,0.013136154,0.0049070856,0.9542068],"study_design_scores_gemma":[0.00043925009,0.00015784202,0.002522204,0.002390469,0.00030590405,0.00009376579,0.0012869738,0.00049924746,0.00017666828,0.0006276553,0.990869,0.0006310576],"about_ca_topic_score_codex":0.00078873534,"about_ca_topic_score_gemma":0.00041533887,"teacher_disagreement_score":0.98596185,"about_ca_system_score_codex":0.000419106,"about_ca_system_score_gemma":0.0004406702,"threshold_uncertainty_score":0.99985325},"labels":[],"label_agreement":null},{"id":"W2609007084","doi":"10.1038/s41598-017-01554-1","title":"Construction of a highly efficient CRISPR/Cas9-mediated duck enteritis virus-based vaccine against H5N1 avian influenza virus and duck Tembusu virus infection","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; Huazhong Agricultural University","keywords":"Virology; Influenza A virus subtype H5N1; CRISPR; Biology; Hemagglutinin (influenza); Virus; Cas9; Gene; Genetics","score_opus":0.00795419727517677,"score_gpt":0.28138267348649376,"score_spread":0.273428476211317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2609007084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935433,0.0005136031,0.0018273849,0.00003705036,0.003479371,0.00032896717,0.000038673224,0.000035289286,0.00019631528],"genre_scores_gemma":[0.9989647,0.00011817873,0.00041313728,0.00004558092,0.00012799798,0.000021473295,0.00015656829,0.00002685697,0.00012550085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979846,0.00003854464,0.0005929541,0.00077622035,0.00029029622,0.00031739473],"domain_scores_gemma":[0.9979487,0.0000101718915,0.0005053874,0.0011277833,0.00024193237,0.00016604253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005852333,0.0002396613,0.00026518563,0.00018113163,0.0004519555,0.00023379181,0.00013996236,0.00017522104,0.000021939979],"category_scores_gemma":[0.00035508865,0.0002439404,0.00011811248,0.00013809055,0.0003041583,0.000015826914,0.00014974979,0.000111048896,0.000005446968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006110039,0.000088828325,0.018333916,0.000067774985,0.000034137567,0.00004771698,0.00006659264,0.0015551188,0.97681713,0.0000023377356,0.0005399661,0.0023853977],"study_design_scores_gemma":[0.0006004662,0.00012406544,0.039042644,0.00007194127,0.000036263104,0.00013378586,0.000025204406,0.00078502094,0.9419212,0.000024781699,0.016970279,0.00026439413],"about_ca_topic_score_codex":0.00046124487,"about_ca_topic_score_gemma":0.00063692266,"teacher_disagreement_score":0.03489596,"about_ca_system_score_codex":0.000027246651,"about_ca_system_score_gemma":0.000108906694,"threshold_uncertainty_score":0.9947601},"labels":[],"label_agreement":null},{"id":"W2611972582","doi":"10.1016/bs.pmbts.2017.03.008","title":"CRISPR/Cas9-Based Genome Editing in Plants","year":2017,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Global Institute for Water Security","funders":"","keywords":"CRISPR; Genome editing; Cas9; Zinc finger nuclease; Genome; Computational biology; Biology; Transcription activator-like effector nuclease; Palindrome; Genome engineering; Effector; Genetics; Gene","score_opus":0.030375817769913882,"score_gpt":0.42292252804774133,"score_spread":0.39254671027782745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2611972582","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012831163,0.99230653,0.0057207346,0.00003822752,0.00013103323,0.00032802936,0.000045432243,0.000005605942,0.000141274],"genre_scores_gemma":[0.13233015,0.86303526,0.0039284327,0.000032053456,0.00013957775,0.00014102773,0.0003618546,0.000025768333,0.000005861894],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998452,0.0000685816,0.00032538647,0.0006460237,0.00012696012,0.00038103072],"domain_scores_gemma":[0.999496,0.000021569476,0.00011153265,0.000270806,0.00002782775,0.00007230831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006128218,0.000246683,0.00042300875,0.00026092902,0.000118999444,0.000041591513,0.00045340517,0.00030609436,0.0000034447467],"category_scores_gemma":[0.000044878358,0.00022599117,0.00009085159,0.00015158216,0.0006698381,0.000005834767,0.000079884594,0.00022483319,0.000001384134],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001586159,0.00006658871,0.00854562,0.0011763218,0.000031716332,0.00006327623,0.000028725612,0.0001770734,0.0015674662,0.0005951654,0.0000010594028,0.9877311],"study_design_scores_gemma":[0.001993011,0.0003534279,0.015959373,0.004736569,0.00013641035,0.00019767028,0.000017502056,0.0011165879,0.0032196064,0.0010184894,0.9692813,0.0019700427],"about_ca_topic_score_codex":0.0000044431436,"about_ca_topic_score_gemma":0.000028105036,"teacher_disagreement_score":0.9857611,"about_ca_system_score_codex":0.000010683325,"about_ca_system_score_gemma":0.00028030138,"threshold_uncertainty_score":0.92156523},"labels":[],"label_agreement":null},{"id":"W2612348884","doi":"10.1158/1538-7445.transcontrol16-b13","title":"Abstract B13: EGF/Ras/Erk signaling controls growth and proliferation through regulation of tRNA synthesis","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Cell biology; Biology; Gene knockdown; Cell growth; MAPK/ERK pathway; RNA interference; Signal transduction; Protein biosynthesis; Epidermal growth factor; Small interfering RNA; Translation (biology); Transcription factor; Messenger RNA; RNA; Molecular biology; Cell culture; Genetics; Gene","score_opus":0.045344381750907145,"score_gpt":0.41079602543770527,"score_spread":0.3654516436867981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2612348884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621046,0.0013251401,0.0011607697,0.00025226202,0.000047084257,0.00021007552,0.000013152721,0.000003988446,0.0007770459],"genre_scores_gemma":[0.9986464,0.00065201113,0.00025643382,0.000008423776,0.00026549777,0.00007400262,0.000007166765,0.000013310542,0.00007675641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927264,0.00003265458,0.00013238475,0.00020318647,0.00018072412,0.00017838897],"domain_scores_gemma":[0.99943346,0.000040277882,0.00005704982,0.00027205696,0.00015532963,0.000041834486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033855854,0.00007092541,0.000106255866,0.000030103107,0.00019260413,0.000060323055,0.00014040091,0.0000937179,0.000022353684],"category_scores_gemma":[0.00038793997,0.00006722542,0.000030024843,0.000026689253,0.00011315124,0.000009889509,0.00006055944,0.000095053896,8.627294e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000073853575,0.000010640094,0.0026914403,0.00008969933,0.000026486992,5.0181563e-7,0.000085415035,0.00022529007,0.9939137,0.00013443838,0.00011499875,0.0026335283],"study_design_scores_gemma":[0.00025906714,0.0000660486,0.033333104,0.00005899189,0.0000075293624,9.744442e-7,0.000041259387,0.00009338113,0.9655559,0.00023592218,0.00027626104,0.00007156863],"about_ca_topic_score_codex":0.00018058416,"about_ca_topic_score_gemma":0.000052181313,"teacher_disagreement_score":0.030641664,"about_ca_system_score_codex":0.000012262651,"about_ca_system_score_gemma":0.00005982522,"threshold_uncertainty_score":0.2741373},"labels":[],"label_agreement":null},{"id":"W2612801470","doi":"10.1101/137067","title":"Priming in a permissive type I-C CRISPR-Cas system reveals distinct dynamics of spacer acquisition and loss","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"Canadian Institutes of Health Research; Connaught Fund","keywords":"CRISPR; Biology; CRISPR interference; Computational biology; Priming (agriculture); Genetics; Adaptation (eye); Cas9; Gene","score_opus":0.008987012292692817,"score_gpt":0.26378439447756397,"score_spread":0.25479738218487114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2612801470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989778,0.0027946425,0.00622627,0.0000549843,0.000489105,0.0004314628,0.00016934724,0.000034922214,0.00002125443],"genre_scores_gemma":[0.99774176,0.00037738474,0.0014855382,0.000011685023,0.0002534881,0.000040053124,0.0000034638165,0.00007676563,0.000009847815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834436,0.000063164895,0.00040311602,0.0006923086,0.0001679545,0.0003291177],"domain_scores_gemma":[0.998178,0.000015605065,0.00036181542,0.0010075249,0.00029881805,0.00013821761],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037203773,0.00037362456,0.00047339464,0.0001308484,0.00008198223,0.00007831814,0.00028790542,0.00051562075,0.0000034003638],"category_scores_gemma":[0.00019195784,0.0004179684,0.000088347,0.00008837659,0.000106564454,0.000007156198,0.00051344285,0.0002856044,0.0000020895613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000083286795,0.000052930114,0.053851143,0.002193821,0.00012034607,0.000068196074,0.00002332946,0.00031728763,0.9429951,0.00024478917,0.00004234364,0.0000074620816],"study_design_scores_gemma":[0.00084566156,0.00015462324,0.495362,0.0019360902,0.00017310676,4.825591e-7,0.000029952915,0.003159875,0.4969535,0.000003118676,0.00039320308,0.0009883803],"about_ca_topic_score_codex":0.00006581224,"about_ca_topic_score_gemma":0.000018916484,"teacher_disagreement_score":0.44604158,"about_ca_system_score_codex":0.00013485254,"about_ca_system_score_gemma":0.00019456184,"threshold_uncertainty_score":0.9998272},"labels":[],"label_agreement":null},{"id":"W2614006244","doi":"10.1038/gim.2017.43","title":"Gene patents still alive and kicking: their impact on provision of genetic testing for long QT syndrome in the Canadian public health-care system","year":2017,"lang":"en","type":"article","venue":"Genetics in Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"Genome Alberta; Ontario Ministry of Health and Long-Term Care; Genome Canada","keywords":"Blueprint; Genetic testing; Context (archaeology); Public health; Long QT syndrome; Health care; Test (biology); Medicine; Business; Political science; Law; Geography; Nursing","score_opus":0.04434974531286323,"score_gpt":0.3459488821463727,"score_spread":0.3015991368335095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2614006244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99111426,0.006494912,0.000770246,0.0005664122,0.0001508479,0.00077719695,0.00004236085,0.000003882657,0.00007986761],"genre_scores_gemma":[0.9984369,0.00019133213,0.0009866486,0.0001225649,0.00012848596,0.000043559412,0.00005958073,0.000026727805,0.0000041625312],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99862057,0.000066468994,0.00037336425,0.00033520555,0.00017395118,0.00043046556],"domain_scores_gemma":[0.99887115,0.000053849973,0.00017090011,0.0006188709,0.00011576141,0.00016945835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006644716,0.00020762699,0.00029582717,0.0001596593,0.00017114072,0.00003578221,0.00039734953,0.00012637059,8.896545e-7],"category_scores_gemma":[0.00031849442,0.0001383335,0.000039137558,0.000084232415,0.00011497038,0.000002646286,0.00007069076,0.00012195477,2.1681508e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000112709226,0.000113453985,0.8063746,0.001790258,0.000147322,0.0002764059,0.0081968205,0.006215925,0.025161209,0.000052581156,0.00019654707,0.15136217],"study_design_scores_gemma":[0.0013684423,0.00207207,0.988258,0.0004676992,0.000015361837,0.00020885149,0.001262269,0.002246591,0.0035952714,0.00001763287,0.00028911466,0.00019869997],"about_ca_topic_score_codex":0.00622676,"about_ca_topic_score_gemma":0.02689305,"teacher_disagreement_score":0.1818834,"about_ca_system_score_codex":0.000098884186,"about_ca_system_score_gemma":0.00024357799,"threshold_uncertainty_score":0.9908636},"labels":[],"label_agreement":null},{"id":"W2615491300","doi":"10.1016/j.celrep.2017.04.064","title":"Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress","year":2017,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Pennsylvania; National Human Genome Research Institute; American Heart Association","keywords":"Microsomal triglyceride transfer protein; Induced pluripotent stem cell; Biology; Missense mutation; Cell biology; Apolipoprotein B; Intracellular; Mutation; Endocrinology; Lipoprotein; Biochemistry; Very low-density lipoprotein; Cholesterol; Gene; Embryonic stem cell","score_opus":0.011942623639651406,"score_gpt":0.2657816243730534,"score_spread":0.253839000733402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2615491300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940481,0.004507673,0.00023025887,0.00000779933,0.000083919585,0.000183214,0.000012527652,0.0000068534287,0.0009196151],"genre_scores_gemma":[0.997895,0.0016695795,0.00014557612,0.000004482129,0.000060437877,0.000011927776,0.000019623109,0.000016412752,0.00017693736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991478,0.0000273111,0.0002101237,0.0003515593,0.00009725323,0.00016600908],"domain_scores_gemma":[0.9991849,0.000013771889,0.00021292115,0.0004587413,0.00004557209,0.00008408617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014874556,0.0001555976,0.00022773971,0.000027554011,0.00007339911,0.00004623821,0.00007015577,0.000121137666,0.0000023184375],"category_scores_gemma":[0.000025493202,0.0001552122,0.000049718896,0.00001654504,0.00009121215,0.000009408626,0.00017060492,0.000066188375,1.5844822e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029534682,0.000054702392,0.12033315,0.00024358452,0.000010093853,0.000052345844,0.00008538625,0.00022408787,0.8774767,2.848636e-7,0.000026927128,0.0014632044],"study_design_scores_gemma":[0.00029519817,0.00006147765,0.13418953,0.00003136423,0.000022388354,0.000024036219,0.000114938965,0.00017610723,0.8645383,0.0000062862464,0.00039392896,0.00014643683],"about_ca_topic_score_codex":0.00048286037,"about_ca_topic_score_gemma":0.00006574888,"teacher_disagreement_score":0.013856378,"about_ca_system_score_codex":0.000007673432,"about_ca_system_score_gemma":0.000034665663,"threshold_uncertainty_score":0.63293695},"labels":[],"label_agreement":null},{"id":"W2616140259","doi":"10.1016/j.molcel.2017.05.007","title":"Synthetic Genomics: Rewriting the Genome Chromosome by Chromosome","year":2017,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Genomics; Genetics; Chromosome; Genome; Rewriting; Computational biology; Gene; Programming language","score_opus":0.00496972017538335,"score_gpt":0.24295880810386267,"score_spread":0.2379890879284793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616140259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9645199,0.008316584,0.013106138,0.00060670753,0.00024119967,0.00036266292,0.0000473156,0.00002908939,0.01277037],"genre_scores_gemma":[0.9972014,0.0003256571,0.0005612206,0.0002951264,0.00024678907,0.00003575157,0.00006860984,0.000065612985,0.0011998686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987152,0.000038519367,0.00021533835,0.0004675298,0.00015068003,0.0004126903],"domain_scores_gemma":[0.99828506,0.0000081096505,0.00012119805,0.0014384475,0.000039562943,0.00010762301],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021294254,0.0002341299,0.00016275169,0.000021188216,0.0004264422,0.00016836758,0.0008243622,0.0001394536,0.000039511408],"category_scores_gemma":[0.00006295873,0.00020598921,0.00015112224,0.00002764032,0.00013885395,0.0000042453294,0.00034207315,0.00015170344,0.00006099084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000059495073,0.000024049063,0.000052185143,0.00002317732,0.000030506584,0.000020378722,0.00003745884,0.00032886345,0.99823165,0.000025977453,0.00048103338,0.0007387787],"study_design_scores_gemma":[0.000325963,0.00007827383,0.00023081673,0.000009591424,0.000029057093,0.000023857114,0.0000405901,0.000171224,0.8753642,0.000044566703,0.12339492,0.0002869416],"about_ca_topic_score_codex":0.000022831997,"about_ca_topic_score_gemma":0.000005545107,"teacher_disagreement_score":0.12291388,"about_ca_system_score_codex":0.000022104798,"about_ca_system_score_gemma":0.00004725329,"threshold_uncertainty_score":0.8399996},"labels":[],"label_agreement":null},{"id":"W2616172523","doi":"10.1007/s11427-017-9031-y","title":"Increased lateral root formation by CRISPR/Cas9-mediated editing of arginase genes in cotton","year":2017,"lang":"en","type":"letter","venue":"Science China Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"CRISPR; Genome editing; Arginase; Gene; Biology; Cas9; Computational biology; Genetics","score_opus":0.009335958507922622,"score_gpt":0.29532871382161824,"score_spread":0.2859927553136956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616172523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9771261,0.0013552618,0.00048283246,0.018753635,0.000944628,0.00027548624,0.000115867224,0.000017809956,0.0009283447],"genre_scores_gemma":[0.9926639,0.00015045452,0.00034261393,0.0053946683,0.0010483717,0.000018270059,0.00024682475,0.00001613695,0.000118738724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975128,0.000053864347,0.00040601517,0.00068116374,0.00071683497,0.00062931067],"domain_scores_gemma":[0.99892265,0.000025522446,0.00036118372,0.00046543096,0.00010588106,0.00011930877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001343561,0.00027166444,0.00029197664,0.0003252155,0.0004041832,0.00015491727,0.0013668428,0.00028488005,0.000013492743],"category_scores_gemma":[0.00078876485,0.00023742733,0.000077227436,0.0004226974,0.0014029079,0.000064884254,0.0002454015,0.00033420816,0.000004443158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011912765,0.000039651466,0.011654675,0.00021140391,0.000009911468,0.000018388757,0.00029691565,0.00051059347,0.7667421,0.000004508581,0.21975392,0.00074600824],"study_design_scores_gemma":[0.00078318024,0.00053197774,0.019840224,0.0003281235,0.000024863546,0.000045401353,0.00019881153,0.0072362106,0.85418254,0.00007705404,0.11575973,0.0009918913],"about_ca_topic_score_codex":0.00033435944,"about_ca_topic_score_gemma":0.000070676615,"teacher_disagreement_score":0.10399419,"about_ca_system_score_codex":0.000029848174,"about_ca_system_score_gemma":0.00044994275,"threshold_uncertainty_score":0.96820056},"labels":[],"label_agreement":null},{"id":"W2616853239","doi":"10.1146/annurev-virology-101416-041616","title":"The Discovery, Mechanisms, and Evolutionary Impact of Anti-CRISPRs","year":2017,"lang":"en","type":"review","venue":"Annual Review of Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":242,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"CRISPR; Biology; Trans-activating crRNA; Archaea; Plasmid; Genetics; Function (biology); Computational biology; Gene; DNA; Genome editing; RNA; Bacteriophage; Escherichia coli","score_opus":0.016718790339470824,"score_gpt":0.3972748609744031,"score_spread":0.3805560706349323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616853239","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000050375584,0.99854016,0.00040899336,0.000029999725,0.00013860052,0.00040178892,0.0003123157,0.0000022623028,0.000115516734],"genre_scores_gemma":[0.0004514377,0.9989879,0.00010515354,0.000025493442,0.00008631707,0.000029322458,0.00014780654,0.000026575473,0.00013997788],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99865884,0.00014453118,0.0005758301,0.00029812942,0.0000994597,0.00022318545],"domain_scores_gemma":[0.99850756,0.00006603266,0.0005381751,0.00075136067,0.00008618351,0.0000506713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004056462,0.00028470767,0.0012600418,0.000037396403,0.00007456384,0.0000074952127,0.00044907047,0.00025303435,0.000005517578],"category_scores_gemma":[0.00031824986,0.00017195298,0.00063697493,0.000042449465,0.00024328801,0.0000046014693,0.00030379297,0.0001438497,0.0000021020755],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001464549,0.000044109875,0.000011190221,0.05231773,0.0007608435,0.0000040208315,0.000008143853,0.0000038194403,0.0006026036,0.00044447317,0.005995141,0.9397933],"study_design_scores_gemma":[0.00007540435,0.00043678124,0.00015589222,0.008352046,0.00044186172,0.000100602694,0.0000032357127,8.420601e-7,0.000040949544,0.000060840295,0.99016345,0.0001681145],"about_ca_topic_score_codex":0.000022077353,"about_ca_topic_score_gemma":0.0000035511682,"teacher_disagreement_score":0.9841683,"about_ca_system_score_codex":0.000009049392,"about_ca_system_score_gemma":0.00020815727,"threshold_uncertainty_score":0.7012039},"labels":[],"label_agreement":null},{"id":"W2619400894","doi":"10.1038/s41598-017-02927-2","title":"Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Center for Advancing Translational Sciences; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canada Research Chairs; National Institutes of Health; Children's Hospital Foundation; Rare Diseases Clinical Research Network; Rare Disease Foundation; BC Children's Hospital","keywords":"Arginase; CRISPR; Urea cycle; Genome editing; Biology; Induced pluripotent stem cell; Exon; Gene knockin; Phenotype; Locus (genetics); Gene; Cell biology; Cas9; Loss function; Cancer research; Genetics; Embryonic stem cell","score_opus":0.024306284560389416,"score_gpt":0.3079653686488158,"score_spread":0.2836590840884264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2619400894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8723533,0.001032794,0.12339953,0.00006638636,0.0022298875,0.00035641642,0.000014318871,0.000004663781,0.00054267014],"genre_scores_gemma":[0.9956013,0.0000035680525,0.0031247821,0.0000032335938,0.00013614156,0.000025566473,0.000024548935,0.000010267658,0.0010705779],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902743,0.000004377358,0.00028327305,0.00034732337,0.00015975165,0.00017781825],"domain_scores_gemma":[0.99832153,0.000007895721,0.00031470179,0.0011444574,0.00017734626,0.00003406843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006916634,0.00008256936,0.000108255605,0.000029129487,0.00030154304,0.00004881364,0.0002542316,0.000052035215,0.0000036082722],"category_scores_gemma":[0.0003429793,0.00006274931,0.00009338383,0.00004090128,0.0002488157,0.000005106835,0.0001309852,0.0000352114,9.508656e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000047400754,0.000032277134,0.00040179637,0.000040875268,0.000011992405,0.0000016349278,0.00010378476,0.040851537,0.9535129,0.000033981923,0.0014361256,0.0035683478],"study_design_scores_gemma":[0.00009657204,0.00003923247,0.00014235628,0.0000130510425,0.000016544067,0.000015084792,0.00003956874,0.009990625,0.9868846,0.00048167814,0.0022106858,0.000070018905],"about_ca_topic_score_codex":0.0000102323675,"about_ca_topic_score_gemma":0.000008104365,"teacher_disagreement_score":0.12324799,"about_ca_system_score_codex":0.0000034164966,"about_ca_system_score_gemma":0.00009456572,"threshold_uncertainty_score":0.25588423},"labels":[],"label_agreement":null},{"id":"W2620568304","doi":"10.1371/journal.pone.0178700","title":"Frameshift indels introduced by genome editing can lead to in-frame exon skipping","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Institute of Genetics; National Institutes of Health; Fondation Institut de Cardiologie de Montréal; U.S. National Library of Medicine; Max-Planck-Gesellschaft; Institut de Cardiologie de Montréal; National Heart, Lung, and Blood Institute; Canada Excellence Research Chairs, Government of Canada; Canadian Institutes of Health Research; David and Lucile Packard Foundation","keywords":"Frameshift mutation; Exon; Exon skipping; Biology; Genetics; Indel; Alternative splicing; Nonsense-mediated decay; RNA splicing; Genome; Stop codon; Computational biology; INDEL Mutation; Gene; Genome editing; Human genome; Nonsense mutation; Exon shuffling; Mutation; RNA; Single-nucleotide polymorphism","score_opus":0.01874914736750231,"score_gpt":0.27310381037380016,"score_spread":0.25435466300629783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2620568304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99579966,0.00034333675,0.0018296826,0.0010909685,0.00009534361,0.00019857373,0.000021457672,0.000015157614,0.0006058446],"genre_scores_gemma":[0.99610615,0.000058935217,0.0022172083,0.00029534835,0.0008306416,0.00003274215,0.000049981158,0.000029503697,0.0003795195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989824,0.000013280619,0.00017669056,0.0003535156,0.00014448672,0.00032958962],"domain_scores_gemma":[0.9992017,0.0000065821027,0.000058920337,0.0005855221,0.00004497027,0.00010227028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014002288,0.00014231002,0.00018104962,0.000048255588,0.000109807246,0.000072227485,0.00031959655,0.00013551557,0.000013452059],"category_scores_gemma":[0.0003680893,0.00016455362,0.000033435113,0.000037616814,0.000027148899,0.000004108804,0.00020204701,0.00016156345,0.000013975115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009465683,0.0000980915,0.004675741,0.00003312696,0.000045034372,0.0000022960894,0.00014282302,0.00009940201,0.993759,0.0000047289664,0.00019080176,0.00093952037],"study_design_scores_gemma":[0.0003421073,0.00012856818,0.012242388,0.000082817176,0.00001778357,0.000001140857,0.00006741755,0.00013386102,0.9849352,0.000022119822,0.0017647875,0.00026177263],"about_ca_topic_score_codex":0.00008921614,"about_ca_topic_score_gemma":0.0002021282,"teacher_disagreement_score":0.008823732,"about_ca_system_score_codex":0.000021855838,"about_ca_system_score_gemma":0.00001928609,"threshold_uncertainty_score":0.6710302},"labels":[],"label_agreement":null},{"id":"W2622791909","doi":"10.1002/bies.201700042","title":"Mechanisms of suppression: The wiring of genetic resilience","year":2017,"lang":"en","type":"review","venue":"BioEssays","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health; Canadian Institute for Advanced Research","keywords":"Biology; Penetrance; Genetics; Allele; Phenotype; Genome; Gene; Suppressor; Mutant; Disease; Computational biology; Medicine","score_opus":0.03844284556125796,"score_gpt":0.37669748957140453,"score_spread":0.3382546440101466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2622791909","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000037332502,0.98988765,0.008872398,0.0000052235605,0.00027600126,0.00025877732,0.0000428064,0.000003930632,0.0006158982],"genre_scores_gemma":[0.006555284,0.99195486,0.0009840613,0.000003244767,0.00010711709,0.000026239402,0.000025602047,0.000029901483,0.0003137086],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989436,0.000051442745,0.00040349909,0.00028171952,0.00014873546,0.00017098186],"domain_scores_gemma":[0.99843794,0.000023829283,0.0003685787,0.0010803792,0.000049831524,0.000039438317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019099079,0.00021936378,0.0005700213,0.00004046445,0.00006243618,0.000010921138,0.0007780209,0.00024662557,0.000012856771],"category_scores_gemma":[0.00009058371,0.00014149421,0.00029682266,0.000049395654,0.00013232468,0.0000010442296,0.00029642993,0.000102125785,0.0000025789936],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000076095293,0.000033059245,0.000008025894,0.008456011,0.00015703254,0.0000041390995,0.000022702096,0.000061620565,0.02737857,0.00025703304,0.0009100286,0.9627042],"study_design_scores_gemma":[0.000094127136,0.000109321365,0.000039493574,0.0029292388,0.00023380727,0.000029569925,0.000013216595,0.000010152528,0.035266276,0.000075496304,0.96096516,0.00023416438],"about_ca_topic_score_codex":0.000008262206,"about_ca_topic_score_gemma":0.0000033725007,"teacher_disagreement_score":0.96247,"about_ca_system_score_codex":0.0000044424064,"about_ca_system_score_gemma":0.000105904524,"threshold_uncertainty_score":0.5769966},"labels":[],"label_agreement":null},{"id":"W2625075029","doi":"10.1016/j.mib.2017.06.001","title":"The CRISPR-Cas app goes viral","year":2017,"lang":"en","type":"review","venue":"Current Opinion in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Biology; Computational biology; Genome; Identification (biology); Genetics; Gene; Ecology","score_opus":0.06891686453963987,"score_gpt":0.44596862583462643,"score_spread":0.3770517612949866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2625075029","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000009093423,0.98878133,0.0005135248,0.000025562027,0.010002288,0.00045942978,0.0001041291,0.000012435625,0.000092188064],"genre_scores_gemma":[0.00003197025,0.99688244,0.000035022862,0.000005127409,0.0013578138,0.00013010304,0.0012535165,0.000042775217,0.00026121235],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99823475,0.00016216892,0.00053804414,0.0005651051,0.000035674366,0.0004642878],"domain_scores_gemma":[0.9987431,0.000049477498,0.0002586628,0.00085988536,0.0000347808,0.00005405046],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003052435,0.00041001837,0.00070473045,0.00008216639,0.00018153763,0.0000561671,0.0008580903,0.00048012694,0.000008028363],"category_scores_gemma":[0.000117919015,0.00028546536,0.0003732601,0.00004848956,0.00020711774,0.0000017854678,0.00040921726,0.00043912258,0.00006822905],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000072859048,0.000029075361,0.00001326298,0.0025304763,0.000064187465,4.7356133e-7,0.000011173951,0.0000030501437,0.00048411483,0.00007355864,0.018508812,0.9782745],"study_design_scores_gemma":[0.00017424622,0.000058083966,0.000008007056,0.0015910869,0.00003291402,0.00006913271,0.0000045731185,0.0000013122218,0.00012195812,0.000014199108,0.9975956,0.0003289031],"about_ca_topic_score_codex":0.0000042629226,"about_ca_topic_score_gemma":0.000011929045,"teacher_disagreement_score":0.97908676,"about_ca_system_score_codex":0.000034907334,"about_ca_system_score_gemma":0.00015628707,"threshold_uncertainty_score":0.99995977},"labels":[],"label_agreement":null},{"id":"W2625158686","doi":"10.71781/26305","title":"Development of a retroviral strategy that efficiently creates nested chromosomal deletions in mouse embryonic stem cells and its exploitation for functional genomics","year":2007,"lang":"en","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Génome Québec; George Washington University","keywords":"Embryonic stem cell; Biology; Stem cell; Computational biology; Genomics; Genetics; Cell biology; Genome; Gene","score_opus":0.009819645730056472,"score_gpt":0.21302188890930296,"score_spread":0.20320224317924648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2625158686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903421,0.0062028454,0.0025190325,0.0000037032703,0.00021370305,0.00035366626,0.00006618033,0.000012259802,0.00028654828],"genre_scores_gemma":[0.99035525,0.00022607476,0.001089498,0.0000053496524,0.000054179774,0.000033613003,0.0010693549,0.000023384126,0.007143266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898213,0.000018070732,0.00026056028,0.0003449304,0.00018250874,0.00021180604],"domain_scores_gemma":[0.99945897,0.0000215196,0.00016427858,0.00011644335,0.00015268885,0.0000860836],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011070488,0.00021364326,0.00018909332,0.00019196245,0.0006294763,0.000015118192,0.00009881223,0.00029363311,0.0000020353905],"category_scores_gemma":[0.00000774064,0.0002606805,0.00009209483,0.00008717323,0.000033170934,0.00001230855,0.000037617832,0.00010535391,8.311566e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062091195,0.00007598817,0.0005356648,0.0001907747,0.000104145955,0.00001592239,0.00265353,0.01445534,0.9799453,0.0002261087,0.000022147588,0.001154173],"study_design_scores_gemma":[0.0009509119,0.00013601723,0.013965684,0.00006685312,0.00006325255,0.000036154823,0.010735377,0.0013882257,0.9703079,0.000003214352,0.0020573002,0.0002891118],"about_ca_topic_score_codex":0.00014218476,"about_ca_topic_score_gemma":0.0021745896,"teacher_disagreement_score":0.01343002,"about_ca_system_score_codex":0.00056553714,"about_ca_system_score_gemma":0.0007764986,"threshold_uncertainty_score":0.99998456},"labels":[],"label_agreement":null},{"id":"W2625973567","doi":"10.1186/s13568-017-0425-y","title":"An enhanced vector-free allele exchange (VFAE) mutagenesis protocol for genome editing in a wide range of bacterial species","year":2017,"lang":"ca","type":"article","venue":"AMB Express","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; National Science Foundation","keywords":"Pseudomonas stutzeri; Biology; Mutagenesis; Genome; Genome editing; Bacterial genome size; Bacillus subtilis; Genetics; Plasmid; Escherichia coli; Mutant; Computational biology; DNA; Bacteria; Gene","score_opus":0.017985658651751307,"score_gpt":0.3281747479184165,"score_spread":0.3101890892666652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2625973567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9099894,0.00045767016,0.02185215,0.00013662632,0.0008389931,0.06471926,0.00069541595,0.000026524363,0.0012839345],"genre_scores_gemma":[0.9434092,0.00006314771,0.002227873,0.00001947417,0.0027808049,0.050888818,0.00011856108,0.000072129755,0.00041997564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821424,0.00006397156,0.00046458733,0.0005718498,0.00016791257,0.00051744404],"domain_scores_gemma":[0.9979307,0.000033221546,0.0003255747,0.0014611386,0.00012852605,0.000120851444],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030737964,0.0003294665,0.00043754475,0.00006414902,0.00016238626,0.000111416135,0.0009351633,0.00028374747,0.0001334999],"category_scores_gemma":[0.00031745256,0.0003614047,0.00017218354,0.000032741376,0.00013285363,0.000023825132,0.0003536588,0.000092137285,0.0000015879027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064262724,0.00014290801,0.00054364733,0.0007384919,0.000057738824,0.000005000479,0.0007540005,0.00013108914,0.99490315,0.000008138581,0.00054241694,0.0015308151],"study_design_scores_gemma":[0.0046638246,0.000705711,0.021742996,0.00014861059,0.00003182359,0.0000017405525,0.00021267137,0.00013569617,0.9309427,0.000021172702,0.040962588,0.00043045759],"about_ca_topic_score_codex":0.00011603949,"about_ca_topic_score_gemma":0.000538001,"teacher_disagreement_score":0.06396042,"about_ca_system_score_codex":0.000027470702,"about_ca_system_score_gemma":0.000059842034,"threshold_uncertainty_score":0.9998838},"labels":[],"label_agreement":null},{"id":"W2626911737","doi":"10.1021/cen-09449-notw6","title":"CRISPR knocks out HIV in cells","year":2016,"lang":"en","type":"article","venue":"C&EN Global Enterprise","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Human immunodeficiency virus (HIV); Virology; Biology; Genetics; Gene","score_opus":0.0038751297723718767,"score_gpt":0.2785003907109402,"score_spread":0.2746252609385683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2626911737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8775117,0.0012558129,0.10979264,0.00044423805,0.00082745,0.00020997573,0.00011838612,0.000039052644,0.009800767],"genre_scores_gemma":[0.99722147,0.00021061396,0.00044622034,0.00014590783,0.0001656807,0.0000111838945,0.000010956579,0.000013517887,0.0017744318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913716,0.00002606949,0.00017241295,0.00029765227,0.00008452087,0.00028218646],"domain_scores_gemma":[0.99954414,0.000007838658,0.000024247625,0.00030630955,0.000021844626,0.00009564231],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007813258,0.00014599889,0.00011594626,0.000022712458,0.00001495495,0.000012588802,0.00020474597,0.00011802513,0.000047798694],"category_scores_gemma":[0.000041238764,0.000115091505,0.00007772465,0.000047303438,0.00002898135,0.0000029101514,0.00013966973,0.000041297575,0.00014112548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011292689,0.00010402466,0.033124097,0.000021297414,0.00003590705,0.000029040462,0.000100880214,0.00021455347,0.9228331,0.00005746353,0.025108265,0.018258456],"study_design_scores_gemma":[0.0021480236,0.0001882021,0.015034482,0.00011533481,0.00001972254,0.000022678214,0.00008184657,0.0001073091,0.7172063,0.00017036535,0.26436818,0.00053756335],"about_ca_topic_score_codex":0.000011835767,"about_ca_topic_score_gemma":0.0000591517,"teacher_disagreement_score":0.23925991,"about_ca_system_score_codex":0.000044579356,"about_ca_system_score_gemma":0.000026792315,"threshold_uncertainty_score":0.46932954},"labels":[],"label_agreement":null},{"id":"W2626968415","doi":"10.1101/150656","title":"Inducible, tunable and multiplex human gene regulation using CRISPR-Cpf1-based transcription factors","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Massachusetts General Hospital; Charles A. King Trust; Howard Hughes Medical Institute","keywords":"Multiplex; Gene; Gene expression; CRISPR; Biology; Regulation of gene expression; Computational biology; Transcription factor; Transcription (linguistics); Cell biology; Genetics","score_opus":0.026497641101064687,"score_gpt":0.2811777506366677,"score_spread":0.25468010953560305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2626968415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9603655,0.0015282851,0.03675773,0.000026254858,0.0005851645,0.0005123418,0.0001329719,0.00008695074,0.000004830971],"genre_scores_gemma":[0.99291813,0.00012213104,0.006255212,0.00003274567,0.000475269,0.000044671564,0.00000971942,0.00013193923,0.000010193128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781835,0.000068201676,0.00040129654,0.0010281813,0.00023283047,0.0004511121],"domain_scores_gemma":[0.9978865,0.000008436627,0.00029692473,0.0013395791,0.0002518691,0.00021672624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032778847,0.0005425428,0.00040562224,0.0001946328,0.00038413523,0.00024196741,0.00035148874,0.00077728037,0.0000128834345],"category_scores_gemma":[0.000098365585,0.0006230029,0.00015432254,0.000087267596,0.000119031276,0.000016306392,0.00021625182,0.00036732721,0.0000017284626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019038358,0.000046563382,0.007431681,0.00024108996,0.000080805476,0.0000052588384,0.000007560061,0.004318699,0.9877944,0.000012315061,0.00004070656,0.0000018722878],"study_design_scores_gemma":[0.00055919454,0.000054988996,0.12888253,0.00014065686,0.000107261025,3.1197683e-8,0.0000022196953,0.0034706667,0.8650902,0.0000014100226,0.0010730522,0.0006177911],"about_ca_topic_score_codex":0.00018201537,"about_ca_topic_score_gemma":0.00001255801,"teacher_disagreement_score":0.12270421,"about_ca_system_score_codex":0.00008327538,"about_ca_system_score_gemma":0.00023030124,"threshold_uncertainty_score":0.9996221},"labels":[],"label_agreement":null},{"id":"W2631627478","doi":"10.1073/pnas.1703133114","title":"Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Government of Canada","keywords":"Endoribonuclease; Phosphodiester bond; RNA; Biology; Ribosomal RNA; Endonuclease; Post-transcriptional modification; Cleavage (geology); 5.8S ribosomal RNA; Cell biology; Biochemistry; Exosome complex; Molecular biology; RNA-dependent RNA polymerase; Gene; Non-coding RNA; RNase P","score_opus":0.03261352492602709,"score_gpt":0.3424229666087721,"score_spread":0.309809441682745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2631627478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930767,0.00026559312,0.00006132326,0.0022891841,0.00006960918,0.00031019954,0.000014971808,0.0000042388524,0.003908174],"genre_scores_gemma":[0.9984856,0.000055145392,0.00090722553,0.000052991505,0.00030790572,0.000015495689,3.6444382e-7,0.0000042907654,0.00017094784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992517,0.0000016672554,0.00013922641,0.00016866757,0.00031865257,0.000120049146],"domain_scores_gemma":[0.9996278,0.000013645027,0.00020198796,0.000019257614,0.000116264586,0.000021010743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053791085,0.00006454773,0.00006613121,0.00001997363,0.00036755577,0.000054512395,0.0009102088,0.000053418316,0.0000018431889],"category_scores_gemma":[0.00023812705,0.000038568927,0.00008446927,0.000058173864,0.0005939905,0.000013633752,0.0001644169,0.00005674613,3.576275e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018456914,0.000020506117,0.0006416905,0.000025376288,0.000012159607,1.881374e-9,0.00003320947,0.00003983427,0.98766935,0.006861482,0.0019702655,0.0027076434],"study_design_scores_gemma":[0.00016575701,0.000054895747,0.01328226,0.000017869119,0.00000765855,0.000002907745,0.00006572847,0.00027566217,0.9746849,0.003195899,0.00819038,0.000056096513],"about_ca_topic_score_codex":0.0000020083273,"about_ca_topic_score_gemma":1.2259434e-7,"teacher_disagreement_score":0.012984489,"about_ca_system_score_codex":0.000003864286,"about_ca_system_score_gemma":0.00001300283,"threshold_uncertainty_score":0.2826979},"labels":[],"label_agreement":null},{"id":"W2644975518","doi":"10.1534/genetics.117.202580","title":"High-Throughput Characterization of Cascade type I-E CRISPR Guide Efficacy Reveals Unexpected PAM Diversity and Target Sequence Preferences","year":2017,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Alfred P. Sloan Foundation; National Science Foundation","keywords":"CRISPR; Trans-activating crRNA; Biology; CRISPR interference; Genetics; RNA interference; RNA; Cas9; Computational biology; DNA; Locus (genetics); Gene","score_opus":0.02698609299134851,"score_gpt":0.3151713460006004,"score_spread":0.2881852530092519,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2644975518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939548,0.00041977112,0.0050974106,0.00004835791,0.00021168834,0.00013443979,0.000049831455,0.000010003261,0.000073732874],"genre_scores_gemma":[0.99394727,0.0011740144,0.0044106906,0.000029665678,0.00013681498,0.0000021303524,0.00010710884,0.000012767292,0.000179537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999249,0.000023879818,0.00018380347,0.0002668681,0.00011020134,0.00016626442],"domain_scores_gemma":[0.99919313,0.0000068951585,0.00013617412,0.00047423554,0.00012477505,0.000064780805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008277106,0.00013064814,0.0001543366,0.000022764625,0.00029279603,0.000026351036,0.00026831063,0.00012562337,0.000010582327],"category_scores_gemma":[0.00011431615,0.000132094,0.000029942163,0.000034225533,0.000106987245,0.000005311554,0.0005936878,0.00005272961,0.0000018230514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018522302,0.000017897208,0.03729729,0.000028839848,0.000032079784,0.0000014271013,0.00018679255,0.00014609449,0.9609566,0.000019915815,0.000096206386,0.0011983842],"study_design_scores_gemma":[0.0002493724,0.00013134448,0.40494817,0.000015707094,0.000023499462,0.000003904682,0.000015852567,0.00008596769,0.59245104,0.000048783386,0.0018932135,0.00013318213],"about_ca_topic_score_codex":0.000086758286,"about_ca_topic_score_gemma":0.000026416106,"teacher_disagreement_score":0.36850554,"about_ca_system_score_codex":0.00000789,"about_ca_system_score_gemma":0.000025403462,"threshold_uncertainty_score":0.53866374},"labels":[],"label_agreement":null},{"id":"W2663079491","doi":"10.1111/jcmm.13236","title":"Expression of <scp>PTEN</scp>‐long mediated by <scp>CRISPR</scp>/Cas9 can repress U87 cell proliferation","year":2017,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Science Foundation of Henan Province; National Natural Science Foundation of China","keywords":"PTEN; CRISPR; Biology; Cell growth; PI3K/AKT/mTOR pathway; Cell; Gene; Cancer research; Cell biology; Molecular biology; Genetics; Signal transduction","score_opus":0.005960309360664519,"score_gpt":0.26253001150359784,"score_spread":0.25656970214293334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2663079491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9009058,0.020011015,0.07728962,0.00018759789,0.00034713553,0.00020815613,0.000013542453,0.0000062821173,0.0010308821],"genre_scores_gemma":[0.9962851,0.0019597975,0.0004416786,0.00014487478,0.0003933952,0.0000050474173,0.00008619261,0.0000419401,0.00064196513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99817204,0.00008752366,0.0006474448,0.0003100729,0.00047467998,0.00030824746],"domain_scores_gemma":[0.9980055,0.00005541957,0.00072838337,0.0005728087,0.0003313144,0.00030655955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060673436,0.00027212754,0.00047217746,0.00012349169,0.00014220038,0.000039770795,0.00037332246,0.00024971727,0.0000050301405],"category_scores_gemma":[0.0011930442,0.00022090973,0.00013975476,0.000059464935,0.00017616239,0.000015885324,0.00013404505,0.00026794142,5.8377634e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015132696,0.00006527617,0.001763976,0.00012592488,0.0000657298,0.0000986182,0.0003286359,0.00010560049,0.99021244,0.0000040480486,0.006783677,0.00043093454],"study_design_scores_gemma":[0.0019167447,0.0006175989,0.0011457638,0.000196325,0.00014503651,0.000096501855,0.00031916355,0.0001805964,0.9820818,0.000028458928,0.013208332,0.000063708045],"about_ca_topic_score_codex":0.000026732887,"about_ca_topic_score_gemma":0.0000053310664,"teacher_disagreement_score":0.09537934,"about_ca_system_score_codex":0.000011246178,"about_ca_system_score_gemma":0.00007530512,"threshold_uncertainty_score":0.90084374},"labels":[],"label_agreement":null},{"id":"W2704159227","doi":"10.1038/nrg.2017.47","title":"Synthetic lethality and cancer","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":681,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Lethality; Synthetic lethality; Biology; Computational biology; Cancer; Genetics; DNA repair; Gene","score_opus":0.058460860415421735,"score_gpt":0.4625632830109952,"score_spread":0.40410242259557344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2704159227","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000052232162,0.99758273,0.00017980445,0.00001974232,0.00065280293,0.0009243735,0.00009246524,0.000010918283,0.0005319273],"genre_scores_gemma":[0.000014848486,0.9968742,0.0007770299,0.00007411708,0.00095754286,0.0001868897,0.00012377316,0.000088295645,0.00090330717],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980109,0.00015352096,0.00056854327,0.00077677827,0.0001468883,0.0003433782],"domain_scores_gemma":[0.9979547,0.000020102429,0.00039662377,0.001412305,0.000056440615,0.00015977405],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004479351,0.0005921527,0.0015659909,0.00005961596,0.00012049337,0.00007233279,0.0005653629,0.0013474516,0.000020050149],"category_scores_gemma":[0.00023100835,0.0004666224,0.00051535165,0.000065003645,0.000104525876,0.0000014707773,0.00031852044,0.00073376554,0.000018269111],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[9.269819e-7,0.000009019839,0.000005549584,0.011078358,0.000086035434,0.0000023146094,0.0000033337765,0.0000010001353,0.00004308475,0.000007947154,0.0018973039,0.9868651],"study_design_scores_gemma":[0.000070712296,0.00003459186,0.0000075318812,0.0053400947,0.00071073486,0.0000654371,5.733115e-7,0.0000021503813,0.000096899574,0.0000065169233,0.99316317,0.00050161825],"about_ca_topic_score_codex":0.0000034690866,"about_ca_topic_score_gemma":0.000018347062,"teacher_disagreement_score":0.99126583,"about_ca_system_score_codex":0.000023087532,"about_ca_system_score_gemma":0.00015523002,"threshold_uncertainty_score":0.99994904},"labels":[],"label_agreement":null},{"id":"W2725337673","doi":"10.1016/j.mib.2017.06.003","title":"Inhibition of CRISPR-Cas systems by mobile genetic elements","year":2017,"lang":"en","type":"review","venue":"Current Opinion in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"CRISPR; Mobile genetic elements; Biology; Effector; Genome editing; CRISPR interference; Plasmid; Computational biology; Trans-activating crRNA; Cas9; Genome; Genetics; Palindrome; Function (biology); Gene; Cell biology","score_opus":0.05227305811563032,"score_gpt":0.41973776959145387,"score_spread":0.36746471147582355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2725337673","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021338742,0.9911259,0.0021395546,0.000001078828,0.0049193315,0.00092339405,0.0006471578,0.0000070884166,0.00002313699],"genre_scores_gemma":[0.00056773453,0.9923332,0.00006011964,0.000001422604,0.0004301059,0.00028024157,0.0062252544,0.000044406075,0.000057516863],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979588,0.00015814856,0.00091698277,0.00057237124,0.000049035407,0.00034465583],"domain_scores_gemma":[0.99871856,0.000014201047,0.0005384448,0.00061666017,0.000056956116,0.00005515566],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019789679,0.00038741482,0.00097548217,0.00015450074,0.00004144006,0.000018477816,0.0003567625,0.00050475483,0.000015639776],"category_scores_gemma":[0.000027737446,0.00036933375,0.00025847147,0.00006625327,0.000103162194,0.0000021677956,0.00022531589,0.00023951863,0.000018907613],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013923117,0.00025686336,0.00015130776,0.029480651,0.00018489297,0.0000013407885,0.00003448638,0.000080320366,0.031320535,0.000008364972,0.038690712,0.8997766],"study_design_scores_gemma":[0.000308012,0.00015951451,0.0000043793357,0.003842627,0.00005019077,0.000051771316,0.000007688443,0.0000043372406,0.0016779484,0.0000011340131,0.9935637,0.00032866167],"about_ca_topic_score_codex":0.000010986095,"about_ca_topic_score_gemma":0.0000019114073,"teacher_disagreement_score":0.954873,"about_ca_system_score_codex":0.000044049622,"about_ca_system_score_gemma":0.00011166401,"threshold_uncertainty_score":0.99987584},"labels":[],"label_agreement":null},{"id":"W2727479110","doi":"10.1534/g3.117.041277","title":"Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens","year":2017,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":681,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Canadian Institute for Advanced Research; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"CRISPR; Computational biology; Genome; Genome editing; Computer science; Genetics; Biology; Gene","score_opus":0.03263420924424068,"score_gpt":0.33258931428237565,"score_spread":0.29995510503813494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2727479110","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2661921,0.58226657,0.14944427,0.0001003195,0.00030431608,0.0008075451,0.000051923045,0.000017335957,0.00081560324],"genre_scores_gemma":[0.9124949,0.07343041,0.013308575,0.000055739256,0.00029674108,0.000037419664,0.00005670667,0.000053289605,0.0002662167],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983642,0.0000919126,0.00035131542,0.0004866477,0.00034837218,0.0003575617],"domain_scores_gemma":[0.99813384,0.000022035743,0.00021958529,0.0011243968,0.00035449324,0.0001456434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007085893,0.0002721022,0.00026118735,0.00007944273,0.0002578422,0.00007767655,0.00045156974,0.00019075187,0.000032131502],"category_scores_gemma":[0.00006730103,0.00028856797,0.00009061365,0.00004293582,0.00018365639,0.0000057418433,0.0003452759,0.000071984534,0.000007592097],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000346964,0.000029830024,0.011026462,0.000043721346,0.00016608609,0.0000018744694,0.00011449399,0.025790805,0.4798262,0.0000069588714,0.00013215402,0.4828267],"study_design_scores_gemma":[0.002088327,0.0009077909,0.102894716,0.0000322499,0.0006169214,0.000047097194,0.00022683904,0.016488798,0.76870537,0.00035720886,0.1066038,0.0010308796],"about_ca_topic_score_codex":0.00001606869,"about_ca_topic_score_gemma":0.00003370458,"teacher_disagreement_score":0.6463028,"about_ca_system_score_codex":0.000018742918,"about_ca_system_score_gemma":0.00014339213,"threshold_uncertainty_score":0.99995667},"labels":[],"label_agreement":null},{"id":"W2735462188","doi":"10.1038/nm.4367","title":"Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism","year":2017,"lang":"en","type":"article","venue":"Nature Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Ontario Genomics; University of Toronto; Heart and Stroke Foundation; Hospital for Sick Children","funders":"","keywords":"Exon; Genetics; Biology; Muscular dystrophy; Congenital muscular dystrophy; CRISPR; RNA splicing; Genome editing; Mutation; Homology directed repair; Duchenne muscular dystrophy; splice; Gene; DNA repair; RNA; DNA mismatch repair","score_opus":0.009164083653839665,"score_gpt":0.2977450335480118,"score_spread":0.28858094989417216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735462188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876816,0.0015430093,0.009757242,0.000014038667,0.00059524283,0.0001632143,0.000007886876,0.000015355192,0.00022240278],"genre_scores_gemma":[0.9977938,0.000090560745,0.0017607654,0.00002071002,0.00012656087,0.0000035063472,0.000016084778,0.000019517443,0.00016852851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917585,0.00002500037,0.00023455887,0.00024381741,0.00016025451,0.00016052225],"domain_scores_gemma":[0.99924034,0.000010854542,0.00014219192,0.0004225115,0.00013875286,0.000045352946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022717577,0.00014013708,0.00027544823,0.000109613946,0.000044465818,0.0000027506178,0.00015625692,0.00033988548,0.000005484372],"category_scores_gemma":[0.00034245354,0.00012483676,0.000099029974,0.00006137083,0.000082529834,0.0000035760343,0.00008005738,0.00026480114,2.0893187e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011194409,0.000030726555,0.0007729035,0.0000463839,0.00007999853,0.0000058216133,0.00009739111,0.0051048747,0.9934132,0.000039539456,0.000034058936,0.00026317168],"study_design_scores_gemma":[0.0011771048,0.00048353744,0.0011676867,0.00010431223,0.00009975176,0.000028934304,0.00008067152,0.1231307,0.87350595,0.000054198958,0.000028474147,0.00013866574],"about_ca_topic_score_codex":0.0002752288,"about_ca_topic_score_gemma":0.000207558,"teacher_disagreement_score":0.11990723,"about_ca_system_score_codex":0.000020739759,"about_ca_system_score_gemma":0.000051010713,"threshold_uncertainty_score":0.50906956},"labels":[],"label_agreement":null},{"id":"W2736224128","doi":"10.1016/j.devcel.2017.07.002","title":"The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription","year":2017,"lang":"en","type":"article","venue":"Developmental Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; H2020 European Research Council; Canada Research Chairs; National Institutes of Health; Cancer Research UK; Human Frontier Science Program; Government of the United Kingdom; Wellcome Trust; National Institute of General Medical Sciences; Wellcome","keywords":"Biology; Argonaute; Genetics; RNA interference; Transposable element; Gene silencing; Piwi-interacting RNA; Trans-acting siRNA; RasiRNA; Intron; Gene; RNA; Small RNA; RNA Helicase A; RNA silencing; RNA splicing; Genome; Helicase","score_opus":0.009668733061981561,"score_gpt":0.2550243900988085,"score_spread":0.24535565703682694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2736224128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99495316,0.00017122967,0.0016732584,0.001057669,0.00034743606,0.00037767077,0.00003344561,0.00002002223,0.0013661027],"genre_scores_gemma":[0.9925161,0.000084433515,0.004202012,0.0020074823,0.000098015975,0.00004475321,0.000014508272,0.000036874157,0.0009957943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878263,0.00001558952,0.00020465678,0.00041261248,0.00016833075,0.00041620355],"domain_scores_gemma":[0.9989895,0.0000052420064,0.000034093744,0.00048207623,0.000036727146,0.00045233383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016072612,0.00019664734,0.00012341212,0.000031233456,0.0005352745,0.00015415535,0.0005294753,0.00008937371,0.00006495552],"category_scores_gemma":[0.000078746016,0.00018145387,0.00006764208,0.00005806969,0.00003241276,0.000009011277,0.00023955372,0.000078646415,0.00021872322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092487906,0.000013392261,0.00013383871,0.000012267414,0.000016512278,0.000005622431,0.0018614802,0.00009279664,0.9887605,0.000016288157,0.0050972477,0.0038975994],"study_design_scores_gemma":[0.0003334077,0.00024847465,0.0043740524,0.000021973015,0.0000070532633,0.000010198223,0.0010524518,0.00003391165,0.729814,0.000012068907,0.2637549,0.0003375346],"about_ca_topic_score_codex":0.00005118639,"about_ca_topic_score_gemma":0.000105134626,"teacher_disagreement_score":0.2589465,"about_ca_system_score_codex":0.000070465285,"about_ca_system_score_gemma":0.00010797855,"threshold_uncertainty_score":0.73994744},"labels":[],"label_agreement":null},{"id":"W2736456985","doi":"","title":"Functional significance of missense variants in BRCA1","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital","funders":"","keywords":"Missense mutation; Biology; Genetics; Gene; Allele; Ovarian cancer; Tumor suppressor gene; Transcription factor; Loss function; Phenotype; Cancer research; Cancer; Carcinogenesis","score_opus":0.0429198932877899,"score_gpt":0.39605091560542166,"score_spread":0.35313102231763177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2736456985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950017,0.0016363855,0.0024091578,0.00020164534,0.00008416379,0.00011645903,0.000009717725,0.000002625983,0.00053818914],"genre_scores_gemma":[0.9988811,0.00029887678,0.00019144519,0.000018244978,0.00013134842,0.000040215487,0.000008460592,0.0000096509075,0.00042063245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931836,0.000024544745,0.0001026788,0.00018319898,0.00016730158,0.0002039095],"domain_scores_gemma":[0.9996673,0.000010588243,0.000011146222,0.00016771985,0.00009709855,0.000046142806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025551257,0.000050409704,0.0000655948,0.000063938096,0.000021825259,0.000004993674,0.0000922679,0.00005708869,0.000058727805],"category_scores_gemma":[0.00006312227,0.000051736602,0.000023544575,0.00017642725,0.00006550727,0.000001251373,0.00004289135,0.000108359294,0.0000056531694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006538943,0.00003112661,0.0006528215,0.000025964984,0.00000937172,0.0000062330682,0.000041663363,0.012265956,0.98540884,0.00012972468,0.00050706166,0.00085582776],"study_design_scores_gemma":[0.0006191211,0.000086866596,0.025620297,0.00003126386,0.0000012380266,0.000004733727,0.000061468214,0.000015892036,0.97024983,0.00021745531,0.0030203324,0.00007149616],"about_ca_topic_score_codex":0.00031206332,"about_ca_topic_score_gemma":0.00020398188,"teacher_disagreement_score":0.024967475,"about_ca_system_score_codex":0.00003438297,"about_ca_system_score_gemma":0.00021563937,"threshold_uncertainty_score":0.21097575},"labels":[],"label_agreement":null},{"id":"W2737167849","doi":"10.1038/s41598-017-07153-4","title":"Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Foundation Fighting Blindness","keywords":"Biology; Rhodopsin; Frameshift mutation; CRISPR; Xenopus; Genetics; Retinitis pigmentosa; Genome editing; PAX6; Cas9; Gene; Point mutation; Retinal degeneration; Phenotype; Computational biology; Mutation; Retinal","score_opus":0.020686002777422562,"score_gpt":0.3173876766272612,"score_spread":0.29670167384983864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2737167849","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9782837,0.0022602333,0.01748774,0.00003085824,0.0014758854,0.00017440617,0.000007078831,0.000005372255,0.00027469217],"genre_scores_gemma":[0.997635,0.00013913291,0.001967424,0.00000416385,0.000114230555,0.000007664411,0.000032845535,0.000018945835,0.000080604856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838275,0.000015258062,0.00048098623,0.0005950293,0.00021374277,0.00031223887],"domain_scores_gemma":[0.99879044,0.000007074873,0.00032302112,0.0006904127,0.00011101295,0.00007804274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084670057,0.0001562702,0.0002173118,0.00008404882,0.00038715376,0.00020736552,0.00015992863,0.000104704515,0.0000048102197],"category_scores_gemma":[0.00029342299,0.0001487043,0.000058357564,0.00006784407,0.00016322473,0.000024113862,0.00024765873,0.00007844597,1.8882461e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008158201,0.000014016668,0.012035595,0.000055523047,0.000011395326,0.000051004266,0.00010952267,0.002964303,0.98205364,0.000004365994,0.00010173195,0.0025907583],"study_design_scores_gemma":[0.00022214561,0.00003366878,0.00025587642,0.00018891279,0.00001991421,0.00016508905,0.00024864008,0.02725048,0.9703563,0.0004358897,0.00061397423,0.00020913439],"about_ca_topic_score_codex":0.0001678569,"about_ca_topic_score_gemma":0.00018239908,"teacher_disagreement_score":0.024286177,"about_ca_system_score_codex":0.000016653146,"about_ca_system_score_gemma":0.000052585845,"threshold_uncertainty_score":0.6063986},"labels":[],"label_agreement":null},{"id":"W2738000304","doi":"10.1108/caer-02-2017-0028","title":"Promise, problems and prospects: agri-biotech governance in China, India and Japan","year":2017,"lang":"en","type":"article","venue":"China Agricultural Economic Review","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Global Affairs Canada","funders":"","keywords":"Corporate governance; Incentive; Scarcity; China; Business; Agriculture; Biotechnology; Agricultural biotechnology; Population; International trade; Economic growth; Economics; Political science; Market economy; Finance; Biology","score_opus":0.005167503196766125,"score_gpt":0.24327993511836513,"score_spread":0.238112431921599,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738000304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8874225,0.109283134,0.0000028437694,0.00080282014,0.000079354264,0.00063941214,0.00001212828,0.000007140587,0.0017506526],"genre_scores_gemma":[0.8482694,0.1509822,0.000104532875,0.000040698324,0.00010702274,0.00005418582,0.000023922203,0.000008956982,0.00040905928],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999153,0.000012264204,0.00023818723,0.00037702286,0.000031314466,0.00018819039],"domain_scores_gemma":[0.999456,0.0000022149154,0.00016162892,0.00029949695,0.000007424514,0.00007322724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013891455,0.00019006363,0.00028269785,0.000007691679,0.00010161138,0.00008222921,0.00019886905,0.000087494365,0.000010705903],"category_scores_gemma":[0.000045104134,0.0001313528,0.00004790078,0.000016377917,0.00005685967,0.000016881382,0.00016628673,0.00011040809,0.0000054365732],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000771489,0.00027242707,0.20052712,0.021731317,0.00042713273,0.00002261556,0.0012155576,0.00036876256,0.41161296,0.003724708,0.01658086,0.3434394],"study_design_scores_gemma":[0.00036661737,0.00006940007,0.97987694,0.0008235105,0.000015652844,0.00006105676,0.0000054958077,0.000019323536,0.003979957,0.000047376914,0.014477156,0.00025753275],"about_ca_topic_score_codex":0.00007294917,"about_ca_topic_score_gemma":0.00012736965,"teacher_disagreement_score":0.7793498,"about_ca_system_score_codex":0.000024370169,"about_ca_system_score_gemma":0.000012702945,"threshold_uncertainty_score":0.5356412},"labels":[],"label_agreement":null},{"id":"W2738622934","doi":"10.17863/cam.1180","title":"Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.","year":2016,"lang":"en","type":"article","venue":"Apollo (University of Cambridge)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Medical Research Council; lékařská fakulta Univerzity Karlovy; National Institutes of Health; Ministero dello Sviluppo Economico; National Cancer Institute; Hospices Civils de Lyon; Institut Gustave-Roussy; Sahlgrenska Universitetssjukhuset; Università degli Studi di Firenze; Jewish General Hospital; Lunds Universitet; Uppsala Universitet; Cancer Australia; University of California, San Francisco; Linköpings Universitet; Cancer Research UK; University of Chicago; McGill University; Univerzita Karlova v Praze; National Breast Cancer Foundation; Umeå Universitet; University of Pennsylvania; Ministère du Développement Économique, de l’Innovation et de l’Exportation; Centre Léon Bérard; Breast Cancer Research Foundation; Susan G. Komen for the Cure","keywords":"Scale (ratio); Ovarian cancer; Mutation; Cancer; Computer science; Genetics; Biology; Gene; Geography; Cartography","score_opus":0.0069873118227249485,"score_gpt":0.22640792778892668,"score_spread":0.21942061596620174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738622934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98495144,0.0005669093,0.01355732,0.00023902094,0.00012913739,0.00010558515,0.00018129445,0.000009251778,0.00026003286],"genre_scores_gemma":[0.99695086,0.0007109794,0.0002300787,0.000012775048,0.000038699276,8.0393187e-7,0.000027958566,0.000011206578,0.0020166135],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992801,0.00003501484,0.00009328234,0.00028980707,0.000101048696,0.00020076557],"domain_scores_gemma":[0.99959654,0.000013753189,0.00008037401,0.00019463274,0.000036160094,0.000078520876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116385905,0.000117330295,0.00015256951,0.00008655168,0.00009986928,0.000008830717,0.00011168924,0.000109021086,0.000029667512],"category_scores_gemma":[0.00001689482,0.00012338262,0.000049712642,0.00008179941,0.00009516426,0.000015483174,0.000114694296,0.000051508192,0.0000027807932],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016419083,0.00002048741,0.13136435,0.0000652665,0.00016396715,0.00004100405,0.0013339325,0.00038981411,0.8564568,0.00003643189,0.0019030361,0.008060719],"study_design_scores_gemma":[0.0025560472,0.00006312804,0.8494034,0.00009342476,0.000069858026,0.000024227676,0.0012415219,0.0006145544,0.1427464,0.000021361515,0.0028317107,0.00033440892],"about_ca_topic_score_codex":0.005483623,"about_ca_topic_score_gemma":0.009355,"teacher_disagreement_score":0.718039,"about_ca_system_score_codex":0.00004971886,"about_ca_system_score_gemma":0.000043582553,"threshold_uncertainty_score":0.82896346},"labels":[],"label_agreement":null},{"id":"W2738755612","doi":"10.1016/j.jogc.2017.05.007","title":"Mitochondrial Replacement Therapy: The Road to the Clinic in Canada","year":2017,"lang":"en","type":"article","venue":"Journal of Obstetrics and Gynaecology Canada","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Université de Montréal; University of Alberta; McGill University; Montreal Neurological Institute and Hospital; University of Ottawa; McGill Genome Centre","funders":"","keywords":"Mitochondrial DNA; Medicine; Mitochondrion; Genetics; Mitochondrial disease; Genome; Bioinformatics; Biology; Gene","score_opus":0.010753728385858701,"score_gpt":0.27031198584459637,"score_spread":0.2595582574587377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738755612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9810735,0.004997498,0.00005466459,0.0028001596,0.010636826,0.00013819049,0.0000074356612,2.665423e-7,0.00029146014],"genre_scores_gemma":[0.99821603,0.0004570011,0.00005367975,0.0009315283,0.00011841045,0.0000040091168,8.7666416e-7,0.000006439348,0.00021201595],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9992141,0.000038941278,0.00027705246,0.00011059345,0.00016051173,0.00019881484],"domain_scores_gemma":[0.99912596,0.00018116208,0.00019056836,0.00032940885,0.00008095164,0.00009192963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025741546,0.000086561064,0.00013828023,0.00002570621,0.00017508939,0.00003130888,0.00041631053,0.00004599565,0.00003072741],"category_scores_gemma":[0.0016191497,0.00005108715,0.000031211683,0.000047790734,0.000025375453,0.000002187835,0.000092269,0.00017036452,1.600104e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015288968,0.000076517135,0.39763907,0.00002071193,0.00047209277,0.0007123884,0.00029708797,0.0058847344,0.0034679356,0.000025082454,0.16430838,0.42694312],"study_design_scores_gemma":[0.0012102342,0.0002592515,0.6698149,0.0000021065541,0.000010952346,0.000018089046,0.0002679987,0.00004699276,0.0011236945,0.00000691203,0.32714075,0.000098162214],"about_ca_topic_score_codex":0.80167955,"about_ca_topic_score_gemma":0.9938569,"teacher_disagreement_score":0.42684495,"about_ca_system_score_codex":0.00024949867,"about_ca_system_score_gemma":0.002685633,"threshold_uncertainty_score":0.47641975},"labels":[],"label_agreement":null},{"id":"W2738903728","doi":"10.7554/elife.28129","title":"CRISPR-mediated genetic interaction profiling identifies RNA binding proteins controlling metazoan fitness","year":2017,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"NIH Office of the Director; Natural Sciences and Engineering Research Council of Canada; University of Toronto; National Institutes of Health; Harvard University","keywords":"CRISPR; RNA-binding protein; Biology; Genetics; Computational biology; RNA; Gene","score_opus":0.015381320852017584,"score_gpt":0.32341267749746555,"score_spread":0.30803135664544795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738903728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96614116,0.00075030926,0.031331245,0.00009688443,0.00082310976,0.00034715445,0.000014893422,0.000036678237,0.0004585394],"genre_scores_gemma":[0.99664235,0.00019670399,0.001875498,0.0000457428,0.00059045426,0.000070408416,0.00006686603,0.00003612663,0.00047585298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988829,0.000029572817,0.0002659635,0.00035047703,0.00018011569,0.00029099095],"domain_scores_gemma":[0.9990749,0.000014371168,0.00016610473,0.0005443132,0.00010835084,0.000092008195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022155064,0.000184596,0.00018744929,0.000063271786,0.0003542808,0.00020342357,0.00030292413,0.0001217518,0.000017753311],"category_scores_gemma":[0.0004620814,0.0001829872,0.000105598425,0.00003371947,0.00005151417,0.000013587263,0.00013891123,0.00013517427,0.000037460508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003508493,0.000018403933,0.0026192921,0.00003301077,0.000077022385,0.000006640788,0.00004496519,0.0010565026,0.9947475,0.000007086581,0.00013748524,0.0012170033],"study_design_scores_gemma":[0.00059280073,0.00006357823,0.0051239426,0.000041213712,0.000036732814,0.000010369176,0.00012490115,0.0026469426,0.987971,0.0000070440196,0.0031463131,0.00023512694],"about_ca_topic_score_codex":0.00004126838,"about_ca_topic_score_gemma":0.00005518088,"teacher_disagreement_score":0.03050116,"about_ca_system_score_codex":0.000014868987,"about_ca_system_score_gemma":0.000036308982,"threshold_uncertainty_score":0.74620014},"labels":[],"label_agreement":null},{"id":"W2740295197","doi":"10.1007/978-3-319-55780-9_21","title":"Gene Therapy in Tyrosinemia: Potential and Pitfalls","year":2017,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Tyrosinemia; Genetic enhancement; Medicine; Bioinformatics; Computational biology; Computer science; Biology; Gene; Genetics","score_opus":0.040804406639116074,"score_gpt":0.46124025874880886,"score_spread":0.4204358521096928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2740295197","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0048774695,0.9942172,0.00004503107,0.000022712911,0.00034424107,0.00027734757,0.000007243644,0.0000037023196,0.00020503881],"genre_scores_gemma":[0.021770176,0.97736126,0.00016789256,0.0000621924,0.00038880124,0.00006473635,0.00013216845,0.000019503444,0.000033240405],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99892414,0.00005046314,0.00031540226,0.00045121982,0.000034137753,0.00022466914],"domain_scores_gemma":[0.9995966,0.000017193363,0.000100515856,0.00022439026,0.0000075777125,0.0000537425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011620277,0.0002796722,0.00072813523,0.000107887856,0.00003484558,0.0000062413797,0.00015130325,0.00030062953,0.00000757611],"category_scores_gemma":[0.000027983304,0.00020219396,0.00004725123,0.000038591694,0.000298132,0.000004890797,0.00013122296,0.00015287712,5.199484e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026125072,0.000033875516,0.00016405179,0.00030799746,0.00002066987,0.000014357435,0.000047071422,0.0000010094784,0.023207529,0.000022944318,0.000024385228,0.97613],"study_design_scores_gemma":[0.0010482704,0.0008707765,0.00004190292,0.00088483666,0.000017131095,0.00011943182,0.00008153253,0.0000023488656,0.00413509,0.000032390897,0.9924867,0.00027958752],"about_ca_topic_score_codex":0.00003101666,"about_ca_topic_score_gemma":0.000025189896,"teacher_disagreement_score":0.99246234,"about_ca_system_score_codex":0.000011684111,"about_ca_system_score_gemma":0.00002243529,"threshold_uncertainty_score":0.82452303},"labels":[],"label_agreement":null},{"id":"W2742893306","doi":"10.1038/s41467-017-02760-1","title":"BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Genome instability; Bloom syndrome; Genetics; Biology; Gene; Helicase; Genome; Sister chromatid exchange; RecQ helicase; DNA; DNA repair; DNA damage; RNA","score_opus":0.014156026737773178,"score_gpt":0.34215437183263836,"score_spread":0.3279983450948652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2742893306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97226936,0.019636517,0.0016793205,0.0026303055,0.0002741057,0.00029298075,0.000045315126,0.00004149099,0.0031306369],"genre_scores_gemma":[0.99399024,0.0017553228,0.0032265985,0.00017691145,0.00009209335,0.000038271348,0.00037083286,0.000017762533,0.000331949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993615,0.000060870258,0.00016219757,0.00019304604,0.000070554815,0.00015180858],"domain_scores_gemma":[0.9987164,0.000029562876,0.000029802757,0.0010696471,0.000110265806,0.00004431518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120193385,0.00010417414,0.00008566805,0.000064752865,0.00012764113,0.000014436988,0.00049502583,0.000242088,0.00003250543],"category_scores_gemma":[0.00008947535,0.00011048691,0.000049308048,0.00015985286,0.000094255956,0.0000039947226,0.00019122746,0.00020279594,0.000015035201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028016962,0.00013407604,0.0030062734,0.000012242151,0.000023606613,6.7433155e-7,0.00024181248,0.00008435347,0.9876971,0.00050853554,0.0039754487,0.0042878264],"study_design_scores_gemma":[0.00060017157,0.00011361774,0.017975641,0.00001858144,0.000017461716,0.000017436865,0.000079222154,0.0014250792,0.65621763,0.00009261675,0.32320514,0.00023738042],"about_ca_topic_score_codex":0.000018939107,"about_ca_topic_score_gemma":0.00262221,"teacher_disagreement_score":0.3314795,"about_ca_system_score_codex":0.000022739408,"about_ca_system_score_gemma":0.00002253658,"threshold_uncertainty_score":0.45055252},"labels":[],"label_agreement":null},{"id":"W2744099942","doi":"10.1038/s41564-017-0004-7","title":"An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9","year":2017,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Biology; Streptococcus thermophilus; Temperateness; Virulence; Cas9; Genome; Prophage; Streptococcus pyogenes; Phagemid; Genetics; Trans-activating crRNA; Genome editing; Microbiology; Bacteriophage; Gene; Virology; Bacteria; Escherichia coli; Staphylococcus aureus","score_opus":0.005496294196583403,"score_gpt":0.32419116457362873,"score_spread":0.3186948703770453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2744099942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99229544,0.004334028,0.0013191539,0.00013100693,0.00084668037,0.00033496626,0.00050096324,0.000040764487,0.00019700873],"genre_scores_gemma":[0.99660325,0.00013807176,0.0007838768,0.0003168849,0.00091631454,0.000030850682,0.0010366874,0.00004630354,0.0001277347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835867,0.00006700098,0.00026152653,0.00079192984,0.000055663448,0.0004652107],"domain_scores_gemma":[0.9983289,0.000013191256,0.00014660657,0.0012740698,0.00009320753,0.00014400395],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001221995,0.0003368615,0.00031914917,0.000053669773,0.00027278933,0.00008645945,0.00071551395,0.00097430515,0.00009369714],"category_scores_gemma":[0.000068464906,0.00031407652,0.00014766291,0.000030704825,0.00017761052,0.000009080046,0.00028493284,0.0004274458,0.000033380966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004266396,0.000084248604,0.01890077,0.000008557478,0.000087977925,0.000019671814,0.00003693761,0.00005879624,0.9750359,0.000019361978,0.0016902142,0.0040148688],"study_design_scores_gemma":[0.00085102546,0.000229611,0.029438587,0.000014739538,0.000032151445,0.000034946785,0.000035755813,0.000037767426,0.9225804,0.000020593834,0.046353996,0.00037037773],"about_ca_topic_score_codex":0.00006346712,"about_ca_topic_score_gemma":0.00032964937,"teacher_disagreement_score":0.05245548,"about_ca_system_score_codex":0.000017304557,"about_ca_system_score_gemma":0.0000604941,"threshold_uncertainty_score":0.99993116},"labels":[],"label_agreement":null},{"id":"W2744797881","doi":"10.1016/j.ajhg.2017.06.012","title":"Human Germline Genome Editing","year":2017,"lang":"en","type":"review","venue":"The American Journal of Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":244,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Provincial Health Services Authority; University of Toronto; St. Michael's Hospital","funders":"Center for Information Technology; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Human Genome Research Institute; U.S. Department of Health and Human Services","keywords":"Workgroup; Human genetics; Germline; Bioethics; Genome editing; Genetics; CRISPR; Political science; Biology; Computer science; Gene","score_opus":0.04415433096477406,"score_gpt":0.4113080399266139,"score_spread":0.36715370896183985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2744797881","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007089073,0.9917122,0.00043211385,0.000018785764,0.00028729354,0.00017716408,0.000021255302,0.0000052813975,0.0002567952],"genre_scores_gemma":[0.00736356,0.986196,0.0004517985,0.00004161894,0.0053127785,0.000006103083,0.000042187745,0.000110556124,0.0004754413],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980008,0.00015771388,0.00094247895,0.0002628625,0.00027078015,0.00036537548],"domain_scores_gemma":[0.9963068,0.000018743824,0.0023326168,0.0010292863,0.00016564508,0.0001469434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006234501,0.00042289228,0.0013311916,0.00013388184,0.00035591712,0.000095339405,0.0015361743,0.00011834395,0.00001612372],"category_scores_gemma":[0.00005087369,0.00029681422,0.00075247424,0.00007994617,0.00043012688,0.0000022531167,0.00030576554,0.00052447035,0.000007029702],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000072797734,0.00005445458,0.000013407351,0.00093166344,0.0008410464,0.000046862395,0.00009384312,0.00020951126,0.0088957,0.000012325078,0.001307541,0.9875864],"study_design_scores_gemma":[0.00015553318,0.0010444344,0.00009454204,0.00080438657,0.0007121317,0.000515634,0.000053351472,0.0000012491182,0.00019665973,0.00002340633,0.996042,0.0003566406],"about_ca_topic_score_codex":0.0000040618356,"about_ca_topic_score_gemma":0.0000057382767,"teacher_disagreement_score":0.99473447,"about_ca_system_score_codex":0.00003090059,"about_ca_system_score_gemma":0.00014657827,"threshold_uncertainty_score":0.9999484},"labels":[],"label_agreement":null},{"id":"W2747183034","doi":"10.1016/j.cell.2017.07.037","title":"A Broad-Spectrum Inhibitor of CRISPR-Cas9","year":2017,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":270,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Paul G. Allen Frontiers Group; Paul G. Allen Family Foundation; Howard Hughes Medical Institute; Canadian Institutes of Health Research; Sandler Foundation; National Institutes of Health; National Science Foundation","keywords":"Cas9; CRISPR; Biology; DNA; Genome editing; Computational biology; Cell biology; Genetics; Gene","score_opus":0.00707313309116966,"score_gpt":0.279499603284483,"score_spread":0.27242647019331334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2747183034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9770654,0.0010999138,0.0060324343,0.000118844866,0.00032375392,0.000076348566,0.000008678853,0.0000072470884,0.015267417],"genre_scores_gemma":[0.99721986,0.00010324321,0.00048979983,0.000022339953,0.00023562611,0.000003051619,0.0000076128686,0.000012406728,0.0019060714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999577,0.0000048300412,0.00009364208,0.00014522983,0.000051650175,0.00012766704],"domain_scores_gemma":[0.9993982,0.0000021845608,0.000052490395,0.00048510623,0.000018916217,0.000043131735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004701599,0.000073726405,0.00007933881,0.000013994309,0.00005856015,0.000016461332,0.00018737366,0.000067318084,0.000024845913],"category_scores_gemma":[0.000023759214,0.000073346775,0.00005817081,0.000009883055,0.00004255424,0.0000013031641,0.00010135295,0.00003919986,0.000012575639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010900617,0.000023288774,0.0009350129,0.000027387958,0.0000074299833,0.0000017224094,0.000024070387,0.000041581017,0.9958696,0.000019307092,0.002514771,0.00052493793],"study_design_scores_gemma":[0.00026523008,0.0000827969,0.0043357634,0.000006239199,0.000006812449,0.0000024576232,0.00001584009,0.00004018527,0.9659945,0.000038763552,0.029124726,0.00008671553],"about_ca_topic_score_codex":0.000019507737,"about_ca_topic_score_gemma":0.000016249414,"teacher_disagreement_score":0.02987512,"about_ca_system_score_codex":0.0000025179374,"about_ca_system_score_gemma":0.000021338528,"threshold_uncertainty_score":0.29909948},"labels":[],"label_agreement":null},{"id":"W2751363320","doi":"10.1016/j.ibmb.2017.08.009","title":"Functional characterization of Pol III U6 promoters for gene knockdown and knockout in Plutella xylostella","year":2017,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"National Natural Science Foundation of China","keywords":"Biology; Promoter; CRISPR; RNA polymerase III; Genetics; Gene knockdown; Small hairpin RNA; Plasmid; Gene; Guide RNA; Cas9; RNA polymerase II; Molecular biology; Computational biology; RNA; Gene expression; RNA polymerase","score_opus":0.009284489438702918,"score_gpt":0.28842535626156796,"score_spread":0.27914086682286504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2751363320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861408,0.000794506,0.012430752,0.00011622264,0.00009719913,0.00022482114,0.00007154566,0.0000050477543,0.000119136654],"genre_scores_gemma":[0.9984637,0.000270092,0.0005005633,0.000065727596,0.000108392436,0.000031881726,0.00039957653,0.000016098511,0.00014400315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915403,0.000013686722,0.00020892678,0.00038566318,0.000038506027,0.00019915657],"domain_scores_gemma":[0.999446,0.0000085772535,0.00011473174,0.00031588672,0.000050274168,0.00006456732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011031631,0.0001668277,0.0001877107,0.000039364862,0.00008511482,0.000019808138,0.00012209038,0.00026312732,0.000004004097],"category_scores_gemma":[0.000072448485,0.0001725969,0.00005422696,0.000022464481,0.00017589514,0.0000032390144,0.00012999214,0.00006161011,1.7257454e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013948623,0.000026525413,0.0015102044,0.00008188215,0.000040378978,0.0000020547643,0.00002394447,0.0000055568535,0.9942329,0.00004370566,0.000008869908,0.0038844917],"study_design_scores_gemma":[0.0010484986,0.00018405046,0.004728825,0.000020635627,0.000016719046,0.000040330786,0.000011612448,0.00007746805,0.99312925,0.00008343009,0.00047439628,0.00018479221],"about_ca_topic_score_codex":0.000020204096,"about_ca_topic_score_gemma":0.000004815393,"teacher_disagreement_score":0.012322895,"about_ca_system_score_codex":0.0000063598563,"about_ca_system_score_gemma":0.000035995334,"threshold_uncertainty_score":0.70382977},"labels":[],"label_agreement":null},{"id":"W2751800749","doi":"10.1016/j.tibtech.2017.08.004","title":"Genome Editing for Global Food Security","year":2017,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Global Institute for Water Security","funders":"","keywords":"Food security; World population; Agriculture; Genome editing; Population; Agricultural productivity; Climate change; Crop; Global population; Natural resource economics; Production (economics); Biotechnology; Business; Biology; Genome; Ecology; Economics; Gene; Environmental health; Medicine; Genetics","score_opus":0.012553953048449636,"score_gpt":0.3234914988353415,"score_spread":0.31093754578689187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2751800749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849272,0.00077242375,0.009821244,0.0011590938,0.00040260743,0.00010524267,0.000083658,0.0000488452,0.0026797012],"genre_scores_gemma":[0.9976927,0.00005340518,0.0017653595,0.000026929541,0.000254822,0.000028111133,0.0000541855,0.000011445155,0.00011306614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923515,0.0000051803718,0.00013325024,0.00029981748,0.00003731733,0.0002892638],"domain_scores_gemma":[0.9993351,0.0000026845323,0.000059725116,0.00055700226,0.000015938995,0.000029558527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009193201,0.00011634024,0.00012710535,0.000062634244,0.00010337555,0.000019492401,0.00038806626,0.00038363336,0.000006714255],"category_scores_gemma":[0.000088574365,0.00012597065,0.00006324302,0.000052993808,0.00010571614,0.0000020596362,0.00020055399,0.00008975556,0.0000015762781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000173274,0.00020893691,0.016164644,0.0000921142,0.00019230637,0.000017292276,0.00008759085,0.00040641462,0.73212004,0.026974317,0.0011776849,0.2223854],"study_design_scores_gemma":[0.0029288095,0.00169662,0.057545543,0.00002162575,0.000030393057,0.00007444698,0.00010777708,0.0007293906,0.7429744,0.010315112,0.18286751,0.0007083758],"about_ca_topic_score_codex":0.000010527943,"about_ca_topic_score_gemma":0.00041521975,"teacher_disagreement_score":0.22167704,"about_ca_system_score_codex":0.000015695714,"about_ca_system_score_gemma":0.000009463854,"threshold_uncertainty_score":0.5136934},"labels":[],"label_agreement":null},{"id":"W2751911121","doi":"10.1186/s40246-017-0116-4","title":"Falling giants and the rise of gene editing: ethics, private interests and the public good","year":2017,"lang":"en","type":"article","venue":"Human Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill Genome Centre; Dalhousie University","funders":"","keywords":"Public relations; Redress; Sociology; Environmental ethics; Political science; Law","score_opus":0.026817580672145645,"score_gpt":0.31439445077985373,"score_spread":0.2875768701077081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2751911121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993696,0.0032313778,0.0015851812,0.00082281185,0.00012343097,0.00015182798,0.0000075700814,0.0000035308392,0.0003782887],"genre_scores_gemma":[0.99803966,0.001108446,0.000398274,0.00006449362,0.00028110394,0.0000058244254,0.00000640548,0.000014340251,0.00008142675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944335,0.000046831614,0.00015740334,0.00016251062,0.000056091114,0.00013378653],"domain_scores_gemma":[0.9993066,0.000031251155,0.00012443715,0.00045860308,0.000041746458,0.00003733625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066081784,0.00009524128,0.00012722028,0.00001296037,0.00037692735,0.000111829315,0.00029809913,0.000088997695,0.0000018623949],"category_scores_gemma":[0.00021232144,0.00006169592,0.000038684186,0.000007207485,0.000636839,0.0000031223767,0.000295324,0.00015715662,4.7093738e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034727703,0.000047946585,0.011337179,0.00019860212,0.00044640436,0.0000046345776,0.0053159297,0.00019540719,0.9350203,0.03762209,0.00032308217,0.009141113],"study_design_scores_gemma":[0.027753714,0.00043543673,0.09721664,0.00016717466,0.00038584546,0.00018823541,0.0021181735,0.007014415,0.7359942,0.010444334,0.11695309,0.0013287298],"about_ca_topic_score_codex":0.000021944421,"about_ca_topic_score_gemma":0.0001019742,"teacher_disagreement_score":0.19902612,"about_ca_system_score_codex":0.0000033596323,"about_ca_system_score_gemma":0.00001612502,"threshold_uncertainty_score":0.28990585},"labels":[],"label_agreement":null},{"id":"W2752403657","doi":"10.1016/j.ajhg.2017.07.014","title":"Variant Interpretation: Functional Assays to the Rescue","year":2017,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":427,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Ontario Institute for Cancer Research; Canadian Institute for Advanced Research","funders":"National Human Genome Research Institute; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; Canada Excellence Research Chairs, Government of Canada; Division of Cancer Prevention, National Cancer Institute; Howard Hughes Medical Institute; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Interpretation (philosophy); Computational biology; Biology; Computer science; Programming language","score_opus":0.01304228263719491,"score_gpt":0.3165963790144947,"score_spread":0.3035540963772998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2752403657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94203186,0.00049353536,0.054478433,0.0020992246,0.0003754168,0.00007491686,0.0000037225732,0.000002180719,0.00044069893],"genre_scores_gemma":[0.99712384,0.00009151803,0.00097044616,0.000508816,0.0010386994,0.0000027386232,0.0000014655211,0.000015074685,0.00024740375],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99929607,0.000059312773,0.00022323395,0.00010237194,0.00017845232,0.00014056973],"domain_scores_gemma":[0.99891704,0.000015852189,0.00025234092,0.00060238806,0.00014140853,0.0000709959],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042859212,0.000096893295,0.00012514033,0.000027041586,0.00036509155,0.00008903725,0.0006996072,0.000018705205,0.000014526925],"category_scores_gemma":[0.00009053888,0.000057495778,0.00010121272,0.00003386465,0.00018845718,0.0000024315618,0.00015938185,0.00013172155,0.0000067127467],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006757826,0.00009995508,0.003555685,0.000012037726,0.00065079733,0.000036314006,0.0018705484,0.11264455,0.7405346,0.00038739902,0.031705026,0.1078273],"study_design_scores_gemma":[0.0017558002,0.009024773,0.6371942,0.0001266841,0.00043903894,0.0018695424,0.0028704144,0.002935313,0.17870018,0.0010762534,0.16302958,0.0009781906],"about_ca_topic_score_codex":0.000009477441,"about_ca_topic_score_gemma":0.00003684898,"teacher_disagreement_score":0.63363856,"about_ca_system_score_codex":0.000009478395,"about_ca_system_score_gemma":0.00004494228,"threshold_uncertainty_score":0.28080258},"labels":[],"label_agreement":null},{"id":"W2753273415","doi":"","title":"Elucidation of Mechanisms of Fetal Hemoglobin Regulation by CRISPR/Cas9 Mediated Genome Editing","year":2016,"lang":"en","type":"dissertation","venue":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Science Foundation; Damon Runyon Cancer Research Foundation; Canadian Institutes of Health Research; Institut de Cardiologie de Montréal; Harvard Stem Cell Institute; Fondation Institut de Cardiologie de Montréal; McKnight Foundation; Simons Center for the Social Brain, Massachusetts Institute of Technology; National Institutes of Health; Charles H. Hood Foundation","keywords":"CRISPR; Genome editing; Computational biology; Biology; Cas9; Genetics; Gene","score_opus":0.008208209225893019,"score_gpt":0.2543192529413184,"score_spread":0.2461110437154254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2753273415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96101254,0.00006390392,0.025467183,0.000030278698,0.00056596956,0.00074194296,0.0023526696,0.00006333616,0.009702152],"genre_scores_gemma":[0.978144,0.00008972183,0.00028908977,0.000029768124,0.00015394701,0.0000057967736,0.012913543,0.000086672095,0.008287465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764806,0.00006381212,0.0005640433,0.0007673285,0.00053530524,0.00042146028],"domain_scores_gemma":[0.9979859,0.000041213327,0.00057619694,0.00055062294,0.0005942451,0.0002518487],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021708336,0.00047273253,0.0005234202,0.0005055764,0.00013248234,0.0001496944,0.00092208694,0.00061297667,0.00025930343],"category_scores_gemma":[0.00034161765,0.00052993867,0.00028920325,0.0004940722,0.000053730866,0.00019923081,0.0004055717,0.00021710542,0.00012725162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005180129,0.00007838369,0.0013640117,0.00025025714,0.00021748099,0.0000074708937,0.00006131018,0.0001525412,0.99424165,0.00013490712,0.0007509763,0.0022229673],"study_design_scores_gemma":[0.0008693599,0.0002398976,0.0107762655,0.000239004,0.00012681376,0.000004594429,0.00013751138,0.0000142588915,0.91513026,0.000096716874,0.07174613,0.0006191796],"about_ca_topic_score_codex":0.00001389079,"about_ca_topic_score_gemma":0.00005610212,"teacher_disagreement_score":0.07911141,"about_ca_system_score_codex":0.00016212265,"about_ca_system_score_gemma":0.00012702323,"threshold_uncertainty_score":0.9997152},"labels":[],"label_agreement":null},{"id":"W2754270182","doi":"10.1038/s41564-017-0026-1","title":"Cheese, phages and anti-CRISPRs","year":2017,"lang":"en","type":"letter","venue":"Nature Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Genetics; Gene","score_opus":0.0038760447522853576,"score_gpt":0.2822118093726535,"score_spread":0.27833576462036813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754270182","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34081474,0.1765059,0.0005121075,0.4611139,0.009954675,0.0013981235,0.0018565141,0.0001731767,0.0076708747],"genre_scores_gemma":[0.49309406,0.0040837415,0.0013206298,0.4576521,0.01609723,0.000043599204,0.008788451,0.00024858935,0.0186716],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985832,0.000047677553,0.0001766609,0.0007055869,0.00004107784,0.00044577278],"domain_scores_gemma":[0.9990393,0.000013208259,0.00012092713,0.00071725016,0.00006622624,0.000043104013],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00009847595,0.00038987765,0.00040337467,0.00008069381,0.00011543116,0.000044697925,0.0004626237,0.004010885,0.000028450193],"category_scores_gemma":[0.000087546854,0.0003586078,0.0001273806,0.000022865122,0.00021335017,0.0000016341453,0.0002789053,0.0019138628,0.000015807178],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000037925654,0.0000031586214,0.00005702568,0.00004540036,0.00006658953,0.00004804875,0.000004812047,7.3644907e-7,0.48006895,0.0000010750218,0.51940805,0.00029237216],"study_design_scores_gemma":[0.00027798396,0.00006442053,0.00039354074,0.000022752138,0.000042922326,0.0004800911,0.000002722029,6.837377e-7,0.11468298,0.000009008733,0.8836636,0.00035929424],"about_ca_topic_score_codex":0.0000065858135,"about_ca_topic_score_gemma":0.000008803251,"teacher_disagreement_score":0.36538598,"about_ca_system_score_codex":0.000009043753,"about_ca_system_score_gemma":0.000047294096,"threshold_uncertainty_score":0.9998866},"labels":[],"label_agreement":null},{"id":"W2754486903","doi":"10.1016/j.cbpa.2017.08.012","title":"Genetic code asymmetry supports diversity through experimentation with posttranslational modifications","year":2017,"lang":"en","type":"review","venue":"Current Opinion in Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Genetic code; Computational biology; Biology; Diversity (politics); Evolutionary biology; Genetics; DNA; Political science","score_opus":0.14646228297833705,"score_gpt":0.4833899856379396,"score_spread":0.3369277026596026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754486903","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033278984,0.9891358,0.008659743,0.00001985128,0.00101641,0.00043332615,0.00024982454,0.000013499112,0.0001387652],"genre_scores_gemma":[0.004402829,0.98888594,0.0015423873,0.0000055020155,0.0005132151,0.00012379752,0.0044892817,0.000027959213,0.0000090809845],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985717,0.000058387348,0.00039188346,0.0006120739,0.00009855765,0.00026738405],"domain_scores_gemma":[0.99918854,0.000030207355,0.00020207604,0.00046084076,0.000047614372,0.000070722366],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006854108,0.00031570505,0.00051159365,0.000072541414,0.000105991116,0.000017008237,0.0003871115,0.00039224353,0.000020310617],"category_scores_gemma":[0.000034826422,0.00027960827,0.00017337677,0.00007915524,0.00015998287,0.0000049300033,0.00025050837,0.00024201104,0.000009403993],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004863511,0.00030759166,0.0016756484,0.0043180394,0.00020552707,0.0000013298902,0.00014614554,0.000040139945,0.0025952964,0.00045626174,0.0015037382,0.98870164],"study_design_scores_gemma":[0.00037747482,0.00007178012,0.00009822549,0.00087033655,0.00006566853,0.000028406905,0.000007891956,0.000011057153,0.0008900638,0.00009685057,0.9970808,0.00040144954],"about_ca_topic_score_codex":0.000008133747,"about_ca_topic_score_gemma":0.0000020555572,"teacher_disagreement_score":0.99557704,"about_ca_system_score_codex":0.000042621414,"about_ca_system_score_gemma":0.00013921266,"threshold_uncertainty_score":0.9999656},"labels":[],"label_agreement":null},{"id":"W2754650985","doi":"","title":"iGEM Calgary 2014: B.s. Detector, A Multiplexed Rapid Diagnostic Device","year":2014,"lang":"en","type":"article","venue":"Journal of undergraduate research in Alberta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Bacillus subtilis; Medicine; Computer science; Intensive care medicine; Biology; Genetics","score_opus":0.023756251602601856,"score_gpt":0.35318923066317404,"score_spread":0.3294329790605722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754650985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9521628,0.008390771,0.014191299,0.020644208,0.0008443169,0.0006095782,0.0000035044022,0.00001054352,0.00314296],"genre_scores_gemma":[0.9955934,0.0023820573,0.0012141132,0.00006643651,0.00036901745,0.000009369935,0.0000060784946,0.00003269786,0.00032680092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979546,0.00037941468,0.00045301294,0.00024157752,0.0004568736,0.0005145129],"domain_scores_gemma":[0.99805826,0.0009885915,0.00010570949,0.00033969095,0.0002631609,0.00024461668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016305308,0.00015909947,0.0002452175,0.00028059987,0.000068831745,0.000044735414,0.00040455052,0.0001365585,0.00000808124],"category_scores_gemma":[0.0028128282,0.0001398716,0.00013016499,0.00023568836,0.00008993535,0.000008677773,0.0001471741,0.0004960083,0.000029399765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004470596,0.00038718496,0.014796122,0.00023117638,0.00022497898,0.00010267111,0.00012764681,0.004122396,0.90687394,0.0010949865,0.010975749,0.060616072],"study_design_scores_gemma":[0.008850009,0.0050119655,0.018577762,0.0008509293,0.00007876756,0.0007572929,0.0001686873,0.011154606,0.6117036,0.013893305,0.32763383,0.0013192799],"about_ca_topic_score_codex":0.0004814759,"about_ca_topic_score_gemma":0.0014487248,"teacher_disagreement_score":0.31665808,"about_ca_system_score_codex":0.00004931138,"about_ca_system_score_gemma":0.00014544245,"threshold_uncertainty_score":0.5703798},"labels":[],"label_agreement":null},{"id":"W2755019340","doi":"10.1007/978-1-4939-7337-8_11","title":"Targeted Mutagenesis in Hexaploid Bread Wheat Using the TALEN and CRISPR/Cas Systems","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Key Research and Development Program of China","keywords":"Transcription activator-like effector nuclease; CRISPR; Genome editing; Palindrome; Biology; Genetics; Cas9; Genome; Effector; Computational biology; Mutagenesis; Gene; Mutation; Cell biology","score_opus":0.024551460406294624,"score_gpt":0.44068460581914626,"score_spread":0.4161331454128516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755019340","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43298572,0.007650031,0.5586267,0.00009651498,0.00028528768,0.00021818157,0.000006936617,0.000006082197,0.00012451888],"genre_scores_gemma":[0.8661868,0.0004063024,0.13303615,0.00010973797,0.00010223825,0.000045314657,0.000015138979,0.00003595699,0.00006238618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824655,0.00056247227,0.00029060262,0.00047285054,0.000054766162,0.0003727646],"domain_scores_gemma":[0.99899113,0.00004455207,0.0000951337,0.0007785749,0.000033517634,0.000057077206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010520869,0.00021606851,0.00029154288,0.00009571962,0.00013112769,0.000055551693,0.00039773996,0.000287878,0.0000033841097],"category_scores_gemma":[0.00038624322,0.00017732788,0.00006648477,0.000071759634,0.00020874628,0.0000036762492,0.00032964576,0.0001649541,6.1622694e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020631918,0.000014623932,0.012744322,0.000024442374,0.000029218922,0.000021557487,0.000058118363,0.0014116653,0.9814317,0.00011774101,0.000007286204,0.0041186656],"study_design_scores_gemma":[0.00071001187,0.000116681644,0.013058205,0.00003488776,0.000026985346,0.000113217946,0.00016657742,0.0055626417,0.9763736,0.0002786045,0.0032106356,0.00034796563],"about_ca_topic_score_codex":0.00061985827,"about_ca_topic_score_gemma":0.00012370636,"teacher_disagreement_score":0.43320104,"about_ca_system_score_codex":0.000021173682,"about_ca_system_score_gemma":0.00003166828,"threshold_uncertainty_score":0.7231221},"labels":[],"label_agreement":null},{"id":"W2755839104","doi":"10.1172/jci.insight.95918","title":"Functional correction of dystrophin actin binding domain mutations by genome editing","year":2017,"lang":"en","type":"article","venue":"JCI Insight","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Parent Project Muscular Dystrophy; Bundesministerium für Bildung und Forschung; School of Medicine, New York University; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Deutsches Zentrum für Herz-Kreislaufforschung; Welch Foundation; Deutsche Forschungsgemeinschaft; York University","keywords":"Dystrophin; Duchenne muscular dystrophy; Exon; Biology; Muscular dystrophy; Genome editing; Induced pluripotent stem cell; Mutation; Genetics; Utrophin; Exon skipping; Cell biology; CRISPR; Gene; Alternative splicing; Embryonic stem cell","score_opus":0.009582990360213232,"score_gpt":0.2703424259421202,"score_spread":0.260759435581907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755839104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9697929,0.000176968,0.024911974,0.00008296682,0.0011018019,0.00007175446,0.000026647467,0.000010064547,0.003824898],"genre_scores_gemma":[0.9973395,0.00002196585,0.0005686398,0.00001168153,0.0005101487,0.0000097921875,0.00019434535,0.000013436365,0.0013304964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994852,0.000010641368,0.00013657106,0.00016251586,0.000087028515,0.00011807539],"domain_scores_gemma":[0.9995678,0.000007744298,0.00011225993,0.00022794625,0.00004531914,0.00003894636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069678936,0.000082571976,0.000079654485,0.000034610657,0.00021946708,0.000029949457,0.00009874805,0.00007826413,0.000037620197],"category_scores_gemma":[0.00007765034,0.00008523931,0.000050498093,0.000026075406,0.00004391065,0.000006202043,0.000051341212,0.00006672332,0.0000075837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011435197,0.000019636556,0.0005796988,0.000007601956,0.000024280294,8.8553463e-7,0.000055823668,0.0006685024,0.99535716,0.000015158922,0.0023971961,0.00086263294],"study_design_scores_gemma":[0.0003959843,0.00010086143,0.010838785,0.000013463948,0.0000145954855,0.000012889535,0.00015189018,0.00022743987,0.92592794,0.000019965195,0.06215522,0.00014097501],"about_ca_topic_score_codex":0.00001827695,"about_ca_topic_score_gemma":0.000012899154,"teacher_disagreement_score":0.06942922,"about_ca_system_score_codex":0.000012855856,"about_ca_system_score_gemma":0.000020047839,"threshold_uncertainty_score":0.34759584},"labels":[],"label_agreement":null},{"id":"W2755929587","doi":"10.1007/s11816-017-0448-5","title":"Genome editing in potato plants by agrobacterium-mediated transient expression of transcription activator-like effector nucleases","year":2017,"lang":"en","type":"article","venue":"Plant Biotechnology Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Food Inspection Agency; McGill University; Agriculture and Agri-Food Canada; University of New Brunswick","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Transcription activator-like effector nuclease; Genome editing; Effector; Agrobacterium; Genetics; Petunia; CRISPR; Genome; Gene; Transformation (genetics); Cell biology","score_opus":0.005622725362318014,"score_gpt":0.23256518219897818,"score_spread":0.22694245683666017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755929587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99761426,0.00064735266,0.0007730926,0.00009851097,0.00035852217,0.00021776349,0.00020952588,0.000039173457,0.000041801297],"genre_scores_gemma":[0.99874157,0.0004294496,0.00015267235,0.00001621708,0.00004971301,0.000019069987,0.0005513613,0.000021548742,0.000018399689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998834,0.000020553136,0.0003572394,0.0004031364,0.0001079607,0.00027709905],"domain_scores_gemma":[0.99911714,0.000009897299,0.00025421302,0.00054392236,0.000016640439,0.000058194713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014535287,0.0001833911,0.00025146967,0.00009458409,0.00008257601,0.000014436319,0.00018835936,0.00045518248,0.000009352833],"category_scores_gemma":[0.00009374446,0.00017814207,0.00006542383,0.000032756332,0.00010311127,0.000008425432,0.00006142826,0.00015915884,0.0000011034239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007407934,0.00006962293,0.004421035,0.00004658976,0.000022273753,0.00012396666,0.00004470213,0.000030226216,0.994427,4.0216875e-7,0.00027221165,0.0004678597],"study_design_scores_gemma":[0.00036434908,0.00012876092,0.032008417,0.00008464338,0.000009558088,0.0002564326,0.000034617547,0.000026853842,0.9561229,0.00000202641,0.0107896,0.00017187782],"about_ca_topic_score_codex":0.000065153115,"about_ca_topic_score_gemma":0.000037230366,"teacher_disagreement_score":0.03830417,"about_ca_system_score_codex":0.000013503737,"about_ca_system_score_gemma":0.00001958579,"threshold_uncertainty_score":0.7264423},"labels":[],"label_agreement":null},{"id":"W2756281840","doi":"10.1016/j.ddmod.2017.08.002","title":"Genome wide conditional mouse knockout resources","year":2016,"lang":"en","type":"article","venue":"Drug Discovery Today Disease Models","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Children's Hospital; Toronto Centre for Phenogenomics; SickKids Foundation; Mount Sinai Hospital; University of Manitoba","funders":"National Human Genome Research Institute; National Institutes of Health; Centre National de la Recherche Scientifique; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; European Commission; Genome British Columbia; Genome Canada","keywords":"Conditional gene knockout; Genome; Computational biology; Genetics; Biology; Knockout mouse; Computer science; Gene; Phenotype","score_opus":0.006559302728496631,"score_gpt":0.24193446395490653,"score_spread":0.2353751612264099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2756281840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8668987,0.0016538311,0.12948324,0.0004133996,0.00007472436,0.00014153347,0.00068006665,0.00003169076,0.0006227817],"genre_scores_gemma":[0.9862811,0.00027284466,0.00008731983,0.00031069043,0.00027830215,0.000049948983,0.0003598133,0.00004013089,0.012319846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988318,0.00003264157,0.00018939532,0.00043454906,0.00020111402,0.00031050466],"domain_scores_gemma":[0.99920076,0.00002215052,0.000041570613,0.00044375792,0.00004125764,0.0002504992],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076014396,0.00020582779,0.00013032871,0.00004682776,0.0000782851,0.00005224165,0.00021820063,0.000055005785,0.00005430676],"category_scores_gemma":[0.00004153909,0.0001574966,0.00015700364,0.000040592447,0.00008542812,0.000026756094,0.00013777857,0.00004233295,0.00003194918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054283434,0.00028742253,0.004715962,0.00008018282,0.00022665664,0.000032762124,0.00020444932,0.13933778,0.8433822,0.0023256796,0.008068918,0.0007951692],"study_design_scores_gemma":[0.0077567743,0.00033204487,0.10745933,0.00034667534,0.0004041318,0.000024917459,0.00041921926,0.006545297,0.61715883,0.03902447,0.21602206,0.004506254],"about_ca_topic_score_codex":0.0000051125235,"about_ca_topic_score_gemma":0.000005163944,"teacher_disagreement_score":0.22622335,"about_ca_system_score_codex":0.000021453936,"about_ca_system_score_gemma":0.00007130304,"threshold_uncertainty_score":0.6422525},"labels":[],"label_agreement":null},{"id":"W2756408218","doi":"10.1038/s41598-017-12262-1","title":"CRISPR/Cas9-induced Targeted Mutagenesis and Gene Replacement to Generate Long-shelf Life Tomato Lines","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":254,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Special Fund for Agro-scientific Research in the Public Interest","keywords":"CRISPR; Cas9; Biology; Mutagenesis; Gene; Genome editing; Genetics; Transgene; Mutant; Genotyping; Genetically modified crops; Transformation (genetics); Computational biology; Biotechnology; Genotype","score_opus":0.014623726815739568,"score_gpt":0.30715493491441054,"score_spread":0.29253120809867095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2756408218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98982656,0.00095320673,0.0043333,0.00028108803,0.004055962,0.00034051464,0.000006204178,0.000032411794,0.00017077125],"genre_scores_gemma":[0.993749,0.000033668017,0.0020973,0.00010565457,0.00036570942,0.00004454979,0.000074962845,0.000032644446,0.0034964993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978855,0.000023005576,0.00040533274,0.0010315547,0.00027253333,0.00038203757],"domain_scores_gemma":[0.99743825,0.0000037644822,0.00019582735,0.0018137195,0.00018260816,0.00036580898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007103461,0.00022778551,0.00020709255,0.00009041814,0.0006381511,0.0005076329,0.00023489443,0.00011958147,0.000032903143],"category_scores_gemma":[0.00044172644,0.00021942837,0.00008197896,0.000085117485,0.000087169465,0.000010392353,0.0003802078,0.000054413144,0.00001258825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020034942,0.000031637905,0.0053228294,0.000022960754,0.000042611155,0.00013687636,0.00006627037,0.00044691956,0.9844028,0.0000014264589,0.008095989,0.0014096607],"study_design_scores_gemma":[0.00017967985,0.0000906255,0.014934521,0.0000140781,0.00002545817,0.00019972643,0.000027121918,0.00026427006,0.9664249,0.000019625664,0.017522482,0.00029750596],"about_ca_topic_score_codex":0.000048008496,"about_ca_topic_score_gemma":0.00007802102,"teacher_disagreement_score":0.017977878,"about_ca_system_score_codex":0.000012493293,"about_ca_system_score_gemma":0.00011024528,"threshold_uncertainty_score":0.8948029},"labels":[],"label_agreement":null},{"id":"W2756992211","doi":"10.1186/s13073-017-0475-4","title":"Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic","year":2017,"lang":"en","type":"article","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Simon Fraser University","funders":"Economic and Social Research Council; University of Tasmania","keywords":"CRISPR; Genome editing; Somatic cell; Cas9; Human genetics; Medicine; Computational biology; Palindrome; Genome; Biology; Bioinformatics; Genetics; Gene","score_opus":0.031445118044267424,"score_gpt":0.3332337283286593,"score_spread":0.30178861028439186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2756992211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9218113,0.06608297,0.00083223893,0.0047670538,0.0003729055,0.00026026394,0.0000012356895,0.00001656555,0.005855462],"genre_scores_gemma":[0.9706823,0.027986532,0.000120042365,0.00021402695,0.00048560376,0.00002229063,0.000018141098,0.000024445977,0.00044659228],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990577,0.000035442787,0.00024585307,0.000275628,0.00012633165,0.00025900643],"domain_scores_gemma":[0.998981,0.000034651497,0.00009448695,0.0007930925,0.00002892503,0.00006784655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005343761,0.00015723018,0.00019448224,0.00005115383,0.00014778663,0.000016980033,0.00047027698,0.000089849535,0.00006969181],"category_scores_gemma":[0.00017588893,0.000107222884,0.000045407975,0.000034825935,0.00011971589,0.0000028266127,0.00011893253,0.00013605345,0.000029733952],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000524128,0.00006608982,0.0059792865,0.00011876124,0.000060553277,0.00002019272,0.006647227,0.00012633692,0.95244324,0.000010419223,0.0003683599,0.034107108],"study_design_scores_gemma":[0.009169357,0.0017749396,0.52761334,0.00031546623,0.00007100041,0.00004623963,0.006409997,0.0013571251,0.1276027,0.0005341508,0.32395062,0.0011550713],"about_ca_topic_score_codex":0.000076582444,"about_ca_topic_score_gemma":0.00012686543,"teacher_disagreement_score":0.82484055,"about_ca_system_score_codex":0.000010320044,"about_ca_system_score_gemma":0.000024145438,"threshold_uncertainty_score":0.43724224},"labels":[],"label_agreement":null},{"id":"W2757471682","doi":"10.1016/j.cjca.2017.07.057","title":"OVER-EXPRESSION OF MYBL2 REJUVENATES EXPLANT DERIVED CARDIAC STEM CELLS FROM AGED DONORS WITH ISCHEMIC CARDIOMYOPATHY","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Telomere; Transcriptome; Stem cell; Senescence; Ischemic cardiomyopathy; Oxidative stress; Myocardial infarction; Internal medicine; Telomerase; Andrology; Gene expression; Immunology; Cell biology; Heart failure; Gene; Biology; Genetics; Ejection fraction","score_opus":0.0069391787822307,"score_gpt":0.22568050368050918,"score_spread":0.2187413248982785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757471682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99224263,0.0027368239,0.0032307927,0.00003465111,0.0007249114,0.000082156264,0.00018281351,0.000001960953,0.00076323765],"genre_scores_gemma":[0.99842966,0.00042023257,0.00035966962,0.000017513154,0.000684344,0.0000031750294,0.000022674181,0.00002412348,0.000038588172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999035,0.00008088695,0.0002913057,0.00020679788,0.00009931827,0.0002867026],"domain_scores_gemma":[0.998678,0.000021901073,0.00030214648,0.00054593507,0.00013093991,0.0003210406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002127422,0.00017439862,0.0005168255,0.00008534606,0.00012003889,0.00002629039,0.00040428844,0.00019416987,0.000004620172],"category_scores_gemma":[0.000036502974,0.00014740304,0.00024302598,0.000022747687,0.00016383632,0.000008532976,0.000045155015,0.00017262278,7.427757e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008533713,9.4811867e-7,0.038591024,0.000011756282,0.00023320984,0.00006883668,0.000087819804,0.0030500095,0.9526701,0.0000010317445,0.004423836,0.0007760789],"study_design_scores_gemma":[0.0006446019,0.00022368747,0.040149014,0.000075988384,0.00009234272,0.000057253805,0.00018941099,0.0000038523717,0.9244309,0.000005868658,0.033944108,0.00018293815],"about_ca_topic_score_codex":0.0009977347,"about_ca_topic_score_gemma":0.0006601996,"teacher_disagreement_score":0.029520271,"about_ca_system_score_codex":0.000028609347,"about_ca_system_score_gemma":0.00038139406,"threshold_uncertainty_score":0.60109216},"labels":[],"label_agreement":null},{"id":"W2757485969","doi":"10.1016/j.cjca.2017.07.319","title":"MODELING THE DILATED CARDIOMYOPATHY WITH ATAXIA SYNDROME (DCMA), A PEDIATRIC MITOCHONDRIAL CARDIOMYOPATHY, USING CARDIOMYOCYTES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Calgary Laboratory Services","funders":"","keywords":"Medicine; Induced pluripotent stem cell; Cardiomyopathy; Dilated cardiomyopathy; Heart failure; Internal medicine; Transplantation; Cardiology; Bioinformatics; Embryonic stem cell; Biology; Genetics","score_opus":0.01680679829154207,"score_gpt":0.24002751500853248,"score_spread":0.2232207167169904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757485969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94231373,0.004252065,0.050684944,0.00006987113,0.0022274812,0.00025840284,0.000097606586,0.000006288129,0.000089628105],"genre_scores_gemma":[0.99547714,0.00020718806,0.000509514,0.000031322987,0.003674315,0.000008491877,0.000014516835,0.00006363244,0.000013851994],"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797577,0.00020881936,0.00050886004,0.00042803574,0.00024223528,0.0006362957],"domain_scores_gemma":[0.9977197,0.00002577605,0.00032030843,0.0010412082,0.00036425082,0.00052874687],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032179928,0.00037035556,0.0007986034,0.00019200057,0.00055438303,0.00017288182,0.00089187373,0.00033323912,0.0000024095561],"category_scores_gemma":[0.00007208333,0.00028574732,0.0004988739,0.00009526266,0.00015950056,0.00002156086,0.00011806289,0.00042235697,0.00000273684],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018281778,0.0000024612934,0.021663744,0.000021469245,0.0013544578,0.0010703941,0.00019496687,0.64043176,0.33397222,0.0000020688042,0.00025509865,0.00084853213],"study_design_scores_gemma":[0.03457361,0.009037152,0.19176638,0.0010378179,0.017910276,0.049333077,0.007968211,0.0525644,0.55097157,0.00034742357,0.07302754,0.01146252],"about_ca_topic_score_codex":0.0038791425,"about_ca_topic_score_gemma":0.0012093158,"teacher_disagreement_score":0.5878674,"about_ca_system_score_codex":0.00011199106,"about_ca_system_score_gemma":0.0011344354,"threshold_uncertainty_score":0.99995947},"labels":[],"label_agreement":null},{"id":"W2757927608","doi":"10.1101/194936","title":"Successful optimization of CRISPR/Cas9-mediated defined point mutation knock-in using allele-specific PCR assays in zebrafish","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Appili Therapeutics (Canada); Dalhousie University","funders":"","keywords":"CRISPR; Point mutation; Gene knockin; Biology; Genetics; Cas9; Primer (cosmetics); Restriction site; LMNA; Genome editing; High Resolution Melt; Molecular biology; Mutant; Mutation; Polymerase chain reaction; Gene; Restriction enzyme; Chemistry","score_opus":0.01391655503099618,"score_gpt":0.2571338151324169,"score_spread":0.24321726010142072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757927608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9073595,0.002255976,0.08898881,0.00006062904,0.000531074,0.00061945495,0.00012184241,0.000045514604,0.000017211356],"genre_scores_gemma":[0.98405296,0.0007968422,0.014710282,0.000025445866,0.00021584851,0.0000669624,0.000015535403,0.000114553164,0.0000015923337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99745905,0.00012315488,0.0007721306,0.0009022178,0.00026769307,0.00047573168],"domain_scores_gemma":[0.9978226,0.000029280709,0.0005185537,0.0011415394,0.00035857013,0.00012948386],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006189055,0.00047868915,0.00056479493,0.00039911413,0.00007021364,0.00010837547,0.00051194866,0.000750365,0.00002109103],"category_scores_gemma":[0.00040709143,0.0005898605,0.0001376811,0.00027200635,0.00008556046,0.000020905261,0.0003785737,0.00043190713,0.0000033051622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005857702,0.00013577212,0.008301167,0.00024076163,0.000051583833,0.000039825423,0.000014033357,0.20365115,0.7874219,0.000019942687,0.000062526706,0.0000028169159],"study_design_scores_gemma":[0.0017566241,0.0000949965,0.063703634,0.00051162124,0.00005508737,1.3974177e-7,0.00001434129,0.052716903,0.879535,0.0000026323742,0.00061435025,0.0009946269],"about_ca_topic_score_codex":0.00018328737,"about_ca_topic_score_gemma":0.000053873016,"teacher_disagreement_score":0.15093423,"about_ca_system_score_codex":0.00014963251,"about_ca_system_score_gemma":0.00034217414,"threshold_uncertainty_score":0.9996553},"labels":[],"label_agreement":null},{"id":"W2759801681","doi":"10.1142/s2529732517400090","title":"CRISPR System: From Adaptive Immunity to Genome Editing","year":2017,"lang":"en","type":"article","venue":"Molecular Frontiers Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Francisco; Connaught Fund","keywords":"CRISPR; Genome editing; Cas9; Computational biology; DNA; Genome; Biology; Acquired immune system; Function (biology); Förster resonance energy transfer; Computer science; Genetics; Gene; Antigen; Physics","score_opus":0.007380483039579626,"score_gpt":0.26923512090389984,"score_spread":0.2618546378643202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2759801681","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3639774,0.0023423042,0.6310397,0.00016371481,0.001261721,0.0001036686,0.000024144894,0.000011737473,0.0010756209],"genre_scores_gemma":[0.96773076,0.000053367494,0.03074441,0.00014160616,0.0011089864,0.000008152856,0.000023297298,0.0000425369,0.00014685493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880904,0.000065036606,0.00025173035,0.00028626405,0.00021528016,0.00037264935],"domain_scores_gemma":[0.9986879,0.0000026655641,0.00016782084,0.0007182662,0.00013171858,0.0002916111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027170987,0.00020782571,0.00021871924,0.00006828575,0.0006059688,0.00025441655,0.0006790167,0.00013223567,0.000010886693],"category_scores_gemma":[0.00012650278,0.00021549953,0.00017389195,0.000029701605,0.00005085717,0.0000093357085,0.0002658397,0.00027297102,0.000015187661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000884002,0.000029777504,0.0012421603,0.000010093768,0.0002977452,0.00017525142,0.00016222922,0.0023068453,0.986257,0.000022578393,0.005245389,0.0041625034],"study_design_scores_gemma":[0.0023296643,0.00094179396,0.04074046,0.00020131882,0.00026376016,0.00046503716,0.003616229,0.0017551957,0.8529773,0.00025094312,0.09515355,0.0013047741],"about_ca_topic_score_codex":0.00007446032,"about_ca_topic_score_gemma":0.000011651772,"teacher_disagreement_score":0.6037534,"about_ca_system_score_codex":0.000057646754,"about_ca_system_score_gemma":0.00005249019,"threshold_uncertainty_score":0.87878156},"labels":[],"label_agreement":null},{"id":"W2760870410","doi":"10.1016/j.molcel.2017.09.002","title":"The Anti-CRISPR Story: A Battle for Survival","year":2017,"lang":"en","type":"review","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Genome editing; Arms race; Cas9; Computational biology; Genome; Battle; Gene; Genetics","score_opus":0.0348125794065268,"score_gpt":0.37391671817545175,"score_spread":0.3391041387689249,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2760870410","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000009477857,0.97617847,0.020336194,0.000031585067,0.0014117103,0.0005999045,0.000068023386,0.000013050219,0.0013515591],"genre_scores_gemma":[0.00016301812,0.99568117,0.0003983145,0.0000128493375,0.0004308917,0.00018470021,0.00029929745,0.00012102682,0.0027087587],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861383,0.00009433395,0.00025205262,0.000494188,0.00013696284,0.00040864528],"domain_scores_gemma":[0.9983559,0.000086343265,0.00018874352,0.0012167741,0.00006060339,0.00009163682],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003748636,0.0003860937,0.00061943865,0.000034572306,0.00031935165,0.00010897485,0.00074931444,0.00034138956,0.0000031420252],"category_scores_gemma":[0.00022591915,0.0002908173,0.00071464473,0.000034639314,0.00007547762,0.0000010701267,0.00020106041,0.00021103345,0.000024147415],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009855768,0.000043603304,0.0000011651791,0.0051469654,0.0003409156,0.000020292806,0.000008913206,0.00003954133,0.0044794255,0.0001043177,0.013691346,0.9761137],"study_design_scores_gemma":[0.0001908989,0.00007233904,5.700752e-7,0.0002358463,0.00026778525,0.000006477771,0.0000051561833,0.000008099401,0.004205569,0.0000061232713,0.9946403,0.00036085906],"about_ca_topic_score_codex":0.0000028715774,"about_ca_topic_score_gemma":0.0000071106015,"teacher_disagreement_score":0.9809489,"about_ca_system_score_codex":0.000016442382,"about_ca_system_score_gemma":0.00022267202,"threshold_uncertainty_score":0.9999544},"labels":[],"label_agreement":null},{"id":"W2762506895","doi":"10.1128/mbio.01581-17","title":"Time-Resolved Transposon Insertion Sequencing Reveals Genome-Wide Fitness Dynamics during Infection","year":2017,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity Western University; Western University","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Government of Canada; National Institutes of Health; Ministry of Agriculture of the People's Republic of China; National Natural Science Foundation of China; Howard Hughes Medical Institute","keywords":"Transposable element; Genome; Biology; Insertion sequence; DNA Transposable Elements; Computational biology; Genetics; Gene","score_opus":0.007980891842500537,"score_gpt":0.26060772969337964,"score_spread":0.2526268378508791,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762506895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861709,0.00011639065,0.012580066,0.00007326305,0.00016303746,0.00012673158,0.00001146797,0.00002899068,0.0007291823],"genre_scores_gemma":[0.9982058,0.0001060974,0.0002177908,0.000026268672,0.00018240398,0.000012316625,0.00011921055,0.000024741623,0.001105394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993055,0.000015902731,0.00015105442,0.0002470164,0.00007362487,0.00020693235],"domain_scores_gemma":[0.9993941,0.0000036116671,0.00006752972,0.00044168113,0.000035493747,0.000057542307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109449276,0.00012944543,0.00011082916,0.000033230386,0.0002654321,0.000053557305,0.00014738743,0.00013652275,0.000015970978],"category_scores_gemma":[0.00006042547,0.00014233161,0.00007395981,0.000025250805,0.000040537634,0.000007975219,0.0000502038,0.00007869795,0.000016549204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026995162,0.000009855947,0.026004491,0.000048946775,0.000023086503,0.0000034046607,0.000046588877,0.0021990282,0.97091776,0.000004040213,0.000017165092,0.00069861795],"study_design_scores_gemma":[0.00049603765,0.00007961773,0.46205395,0.00003891267,0.00002400926,0.0000134057045,0.000012968216,0.0022247666,0.5338317,0.00003295546,0.0009227724,0.00026889925],"about_ca_topic_score_codex":0.00007919513,"about_ca_topic_score_gemma":0.00022349636,"teacher_disagreement_score":0.43708608,"about_ca_system_score_codex":0.00006167216,"about_ca_system_score_gemma":0.000017983599,"threshold_uncertainty_score":0.5804115},"labels":[],"label_agreement":null},{"id":"W2762515279","doi":"10.1038/s41467-017-00866-0","title":"Non-canonical reader modules of BAZ1A promote recovery from DNA damage","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stemcell Technologies","funders":"Genentech; Constellation Pharmaceuticals","keywords":"Chromatin; Bromodomain; Histone; DNA damage; Genetics; Nucleosome; Biology; DNA; Chromatin remodeling; Cell biology; Epigenetics; DNA repair; PHD finger; Computational biology; Gene; Transcription factor; Zinc finger","score_opus":0.013989662739287501,"score_gpt":0.3293680940143842,"score_spread":0.31537843127509674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762515279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98433733,0.0047851386,0.001750844,0.0014031677,0.00020011938,0.00017990227,0.00013402684,0.000012758317,0.007196743],"genre_scores_gemma":[0.9844371,0.0008814986,0.013991338,0.000063383384,0.00009723706,0.000013227099,0.00027975714,0.000016138229,0.00022028937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994721,0.000021873542,0.00015154133,0.00017015853,0.00007329818,0.00011107116],"domain_scores_gemma":[0.99655914,0.000022116985,0.00009704049,0.0031947808,0.00008223037,0.000044710298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096111246,0.00009518379,0.0001182925,0.00002075546,0.00018305657,0.000028871716,0.0012271629,0.00029280767,0.000009783119],"category_scores_gemma":[0.00015286617,0.00009472633,0.000078933095,0.00002446413,0.000131962,0.0000052754326,0.0005630413,0.00030348857,0.0000043545956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002070511,0.000091095404,0.0032790299,0.000009455368,0.000097645556,5.1295876e-7,0.00005946293,0.000054230313,0.98889285,0.0002801051,0.003541614,0.0036733197],"study_design_scores_gemma":[0.00051768613,0.00009534862,0.3192557,0.000057847254,0.00005638418,0.0000028783973,0.000047031088,0.0009518098,0.5857605,0.00031336042,0.0926679,0.0002735986],"about_ca_topic_score_codex":0.00005692265,"about_ca_topic_score_gemma":0.00047835347,"teacher_disagreement_score":0.40313238,"about_ca_system_score_codex":0.0000074460495,"about_ca_system_score_gemma":0.000044760658,"threshold_uncertainty_score":0.38628277},"labels":[],"label_agreement":null},{"id":"W2762534636","doi":"10.1016/j.stem.2017.09.010","title":"Human Embryo Editing: Opportunities and Importance of Transnational Cooperation","year":2017,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Francis Crick Institute","keywords":"Genome editing; CRISPR; Biology; Scopus; Pace; Zhàng; Corporate governance; Library science; Computational biology; Engineering ethics; Genetics; Political science; Computer science; MEDLINE; China; Gene; Law; Management","score_opus":0.021166412065747445,"score_gpt":0.27664907514892245,"score_spread":0.255482663083175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762534636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861511,0.0005709865,0.0012949962,0.000110193876,0.00009436023,0.000068132475,0.000014746615,0.000004037321,0.011691466],"genre_scores_gemma":[0.9961123,0.00006959751,0.00015200404,0.000018414428,0.00011104758,0.0000043339883,0.00004722299,0.000009366703,0.0034757177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99960244,0.0000067826436,0.00012445799,0.00012941983,0.000056376528,0.000080509795],"domain_scores_gemma":[0.9996428,0.0000024675599,0.00007432821,0.00019649883,0.000046441728,0.00003748962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007574186,0.000070728565,0.0000720087,0.000012951272,0.00012152537,0.000024916559,0.00009256072,0.000055906152,0.000016232436],"category_scores_gemma":[0.0000017838266,0.00007396127,0.000025221692,0.0000055670002,0.000051064813,0.000003723062,0.000028876304,0.00002871978,3.0739608e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002957329,0.000017893419,0.0013001199,0.0000759989,0.0000050324325,0.0000013178932,0.00005810336,0.000104590436,0.9969213,0.00075369247,0.00044064005,0.00031836837],"study_design_scores_gemma":[0.00033948338,0.00007937304,0.0047354624,0.0000046398745,0.000010138932,0.0000021130143,0.0001542536,0.00013716628,0.98834324,0.000016581114,0.0060766325,0.00010091376],"about_ca_topic_score_codex":0.0000021565384,"about_ca_topic_score_gemma":0.00001564897,"teacher_disagreement_score":0.009961214,"about_ca_system_score_codex":0.0000021732503,"about_ca_system_score_gemma":0.000021592525,"threshold_uncertainty_score":0.3016053},"labels":[],"label_agreement":null},{"id":"W2762982342","doi":"10.1016/j.jogc.2017.08.028","title":"CRISPR Gene Editing Should Be Allowed in Canada, But Under What Circumstances?","year":2017,"lang":"en","type":"article","venue":"Journal of Obstetrics and Gynaecology Canada","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Medicine; Genome editing; Genetics; Gene; Computational biology; Biology","score_opus":0.01595739030356796,"score_gpt":0.2684308128277151,"score_spread":0.2524734225241471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762982342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.974202,0.013053155,0.00055653113,0.0010756612,0.010817794,0.00006125126,0.000015944295,7.3075125e-7,0.00021696178],"genre_scores_gemma":[0.9976033,0.0012288517,0.0001795503,0.00076456973,0.00012283228,0.0000015640351,0.0000048799634,0.000013781749,0.000080651196],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989057,0.000023676697,0.00036236405,0.0001735629,0.00022798663,0.0003066866],"domain_scores_gemma":[0.99897754,0.00015085773,0.00031109047,0.0002356959,0.00015184315,0.00017296534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018723865,0.00013964697,0.00025287038,0.00006907274,0.00014041647,0.000073300194,0.00030026835,0.00011497735,0.00002602718],"category_scores_gemma":[0.0011689824,0.00013725297,0.000039247654,0.000052267274,0.00003977026,0.000017596969,0.00008843919,0.00023470799,4.041436e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039290546,0.00014176466,0.7127059,0.0001960683,0.0007774637,0.008592901,0.00019613987,0.034409847,0.056881014,0.00011804693,0.025971387,0.15997015],"study_design_scores_gemma":[0.0030410993,0.00024923118,0.92032397,0.000023244273,0.000066567496,0.00015731106,0.0026413507,0.00042614248,0.029842062,0.00007805301,0.042629227,0.00052174827],"about_ca_topic_score_codex":0.72601324,"about_ca_topic_score_gemma":0.9909371,"teacher_disagreement_score":0.26492387,"about_ca_system_score_codex":0.00051711366,"about_ca_system_score_gemma":0.0029146932,"threshold_uncertainty_score":0.5597013},"labels":[],"label_agreement":null},{"id":"W2763878102","doi":"10.1186/s13059-017-1325-9","title":"Perfectly matched 20-nucleotide guide RNA sequences enable robust genome editing using high-fidelity SpCas9 nucleases","year":2017,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Transgenic Science and Technology Program; National Key Research and Development Program of China; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Genome editing; Biology; High fidelity; Guide RNA; Computational biology; Genome; Fidelity; Genetics; Transcription activator-like effector nuclease; Subgenomic mRNA; Gene; Computer science; Telecommunications","score_opus":0.02337835001626479,"score_gpt":0.31693975445692907,"score_spread":0.29356140444066425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763878102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985496,0.0024989122,0.008964784,0.0001737208,0.00074468926,0.00022607368,0.00013685181,0.000047030946,0.0017119388],"genre_scores_gemma":[0.9879766,0.00031137944,0.008672374,0.00018764235,0.0021022325,0.000013982207,0.0002242535,0.00005397905,0.00045754397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979442,0.0000759296,0.0004415195,0.00072618795,0.000099492514,0.0007127019],"domain_scores_gemma":[0.9984095,0.000018496583,0.0002612859,0.0010013639,0.00013355959,0.00017577842],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042430012,0.00033647014,0.00039000183,0.000070599686,0.0006055529,0.0001194239,0.0007162827,0.00030397234,0.00017351334],"category_scores_gemma":[0.00024202865,0.00033431948,0.00015350904,0.000049671744,0.00028422353,0.000014501823,0.0004991833,0.0001655517,0.00004276612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021204329,0.000021770911,0.002774077,0.00003390233,0.000094915,0.000014780328,0.000036563215,0.0069620837,0.9893144,0.000052821542,0.00012449801,0.00054901274],"study_design_scores_gemma":[0.0020032786,0.0009948808,0.05256023,0.00007246196,0.00026262214,0.00025350106,0.00060627796,0.001897062,0.78926504,0.00088262965,0.14907707,0.0021249587],"about_ca_topic_score_codex":0.00092197023,"about_ca_topic_score_gemma":0.00014688162,"teacher_disagreement_score":0.20004934,"about_ca_system_score_codex":0.000059776066,"about_ca_system_score_gemma":0.000098404336,"threshold_uncertainty_score":0.9999109},"labels":[],"label_agreement":null},{"id":"W2765306825","doi":"10.1128/mcb.00302-17","title":"A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Université de Montréal; McGill University; University Health Network; Institute for Research in Immunology and Cancer","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Government of Canada; National Institutes of Health; Canada Research Chairs","keywords":"Biology; CRISPR; Genetics; Gene; Genome; Computational biology; Proteome; Ribosome biogenesis; Ribosome; RNA","score_opus":0.00592442357926305,"score_gpt":0.25959445718093294,"score_spread":0.2536700336016699,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765306825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902684,0.0016577697,0.007328969,0.00012084687,0.000105104526,0.00036303414,0.000058542195,0.0000060821058,0.000091257636],"genre_scores_gemma":[0.99936867,0.000028465622,0.0002689756,0.00005630216,0.000076910765,0.0000067724477,0.00007769454,0.00001207015,0.00010416804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989861,0.000116110896,0.00018040894,0.00039723204,0.0000830204,0.0002370824],"domain_scores_gemma":[0.9991281,0.000007772992,0.00014155067,0.00058758137,0.00006174585,0.00007324155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018681843,0.00018394724,0.00022494823,0.000024905086,0.000583257,0.00003044738,0.00033169298,0.00021798651,0.000007463569],"category_scores_gemma":[0.00007532611,0.00014601917,0.00010279784,0.000021639491,0.000496029,0.0000046727587,0.0010121084,0.00012959627,2.804997e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035615092,0.000012893519,0.036001977,0.000041955333,0.000045276745,0.0000030773667,0.000054543656,0.000029534756,0.96341753,0.00021935826,0.000024905412,0.00011330675],"study_design_scores_gemma":[0.0005963824,0.00017185889,0.220051,0.0000061605565,0.00004943362,0.000009770245,0.00002731379,0.000014012268,0.77822405,0.00053382496,0.0001512571,0.00016489305],"about_ca_topic_score_codex":0.00044293355,"about_ca_topic_score_gemma":0.000062753636,"teacher_disagreement_score":0.18519348,"about_ca_system_score_codex":0.0000069767298,"about_ca_system_score_gemma":0.000015210542,"threshold_uncertainty_score":0.5954489},"labels":[],"label_agreement":null},{"id":"W2765526825","doi":"10.1007/978-1-4939-7374-3_19","title":"From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Dystrophin; CRISPR; Duchenne muscular dystrophy; Exon; Biology; Utrophin; Genetics; Gene; Computational biology","score_opus":0.04328729529551085,"score_gpt":0.4691693143321801,"score_spread":0.4258820190366693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765526825","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37456274,0.00021617037,0.6238072,0.00023750607,0.00062870677,0.00050742645,0.000029401393,0.0000060765483,0.000004774866],"genre_scores_gemma":[0.56778944,0.000013150991,0.43160662,0.00003055811,0.0002471514,0.00015608057,0.00012036055,0.000022768265,0.000013873497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99768454,0.0008957089,0.0005144915,0.00053551164,0.00011121506,0.00025853256],"domain_scores_gemma":[0.9981375,0.00010857416,0.00036830577,0.0011016921,0.00023064161,0.00005329516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015215689,0.00021467874,0.00025695813,0.00010325306,0.0003572314,0.00007170236,0.0005394986,0.00025877924,0.000003677641],"category_scores_gemma":[0.0011589443,0.00016145797,0.00015727883,0.00013304182,0.0000910008,0.000011311738,0.00014317119,0.00017082473,6.7660136e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000856582,0.000025288979,0.000050819053,0.000008315812,0.00004730818,0.000001226363,0.0001400838,0.0449984,0.9446123,0.00010743867,0.000025457017,0.009897676],"study_design_scores_gemma":[0.00042032902,0.00022155893,0.0017028515,0.000018871782,0.00007278027,0.000010803074,0.00023630152,0.022697292,0.97271776,0.0011705891,0.00055745273,0.00017338834],"about_ca_topic_score_codex":0.00052041735,"about_ca_topic_score_gemma":0.00007940552,"teacher_disagreement_score":0.19322671,"about_ca_system_score_codex":0.00004223056,"about_ca_system_score_gemma":0.000071942944,"threshold_uncertainty_score":0.65840644},"labels":[],"label_agreement":null},{"id":"W2765734704","doi":"10.1038/nmeth.4466","title":"CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens","year":2017,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"CRISPR; Biology; Reprogramming; Induced pluripotent stem cell; Computational biology; Genome editing; Cas9; Negative selection; Single-cell analysis; Embryonic stem cell; Genetics; Gene; Cell; Genome","score_opus":0.01867576945757532,"score_gpt":0.40833401607916214,"score_spread":0.3896582466215868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765734704","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2547064,0.009650532,0.7216443,0.00023676662,0.0010973292,0.00025952744,0.00003721156,0.00003601067,0.012331903],"genre_scores_gemma":[0.76784945,0.000089418565,0.23059228,0.00012367322,0.00042041775,0.0000049836344,0.000021629226,0.000037353202,0.00086076756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986854,0.00012569841,0.00029658896,0.00041837405,0.00015938742,0.0003145581],"domain_scores_gemma":[0.9984164,0.00005815849,0.00019658133,0.0010663458,0.00015094387,0.00011155037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007447508,0.00023849818,0.00030848428,0.00006604666,0.00016224895,0.00005215775,0.00049985724,0.0006152807,0.000024275627],"category_scores_gemma":[0.0008621057,0.00022740895,0.00021207385,0.000057618654,0.00008783426,0.0000062996346,0.00020103557,0.00046145447,0.0000024634876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041637148,0.000063957545,0.000524036,0.00007554883,0.000050039627,0.000005490542,0.000050563674,0.00013072183,0.98200583,0.000029941873,0.00084616145,0.016176078],"study_design_scores_gemma":[0.0005425408,0.00017053552,0.0032694822,0.000031480573,0.000075012395,0.000012552682,0.000050783055,0.0003357956,0.9698376,0.000034400528,0.025389004,0.00025081285],"about_ca_topic_score_codex":0.000019446106,"about_ca_topic_score_gemma":0.0000150553215,"teacher_disagreement_score":0.51314306,"about_ca_system_score_codex":0.000009970596,"about_ca_system_score_gemma":0.00003590117,"threshold_uncertainty_score":0.92734677},"labels":[],"label_agreement":null},{"id":"W2766874121","doi":"10.1038/nrmicro.2017.120","title":"Anti-CRISPR: discovery, mechanism and function","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":409,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Horizontal gene transfer; Mobile genetic elements; Archaea; Computational biology; Function (biology); Mechanism (biology); Genetics; Limiting; Genome editing; Gene; Evolutionary biology; Genome","score_opus":0.023266054872840364,"score_gpt":0.372061683673262,"score_spread":0.3487956288004216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766874121","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012830961,0.9952661,0.0021570201,0.000015030011,0.0013211635,0.0009026469,0.00012355384,0.000014233379,0.00018741957],"genre_scores_gemma":[0.00006951969,0.9960406,0.00029979966,0.00013041425,0.0007596879,0.000077743694,0.0012938885,0.0000674025,0.0012609486],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980066,0.00019577077,0.00054796116,0.0008499787,0.000034114324,0.0003655722],"domain_scores_gemma":[0.9984838,0.000018400538,0.0004351121,0.00094897446,0.000037171605,0.00007659043],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00040566557,0.000601962,0.0019033748,0.00009783904,0.00013150231,0.000067995534,0.00043760327,0.0019605628,0.000012045819],"category_scores_gemma":[0.00012631252,0.00044766715,0.000573582,0.00005651353,0.00009469805,0.0000053733042,0.00033778808,0.00081577356,0.00004529381],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005093391,0.000018534083,0.0000016833073,0.007832497,0.00021903309,0.000004645358,0.0000025538209,1.0564021e-7,0.013158596,0.0003341656,0.0069697765,0.9714533],"study_design_scores_gemma":[0.00012787725,0.00010883583,0.0000018057879,0.0022611548,0.00057091267,0.000429349,8.552071e-7,1.4084986e-7,0.00043842537,0.000030543622,0.9955671,0.00046299995],"about_ca_topic_score_codex":0.0000022363733,"about_ca_topic_score_gemma":0.000010775422,"teacher_disagreement_score":0.98859733,"about_ca_system_score_codex":0.000018871395,"about_ca_system_score_gemma":0.000088139626,"threshold_uncertainty_score":0.9997975},"labels":[],"label_agreement":null},{"id":"W2766913168","doi":"10.1101/204339","title":"Efficient generation of targeted large insertions in mouse embryos using 2C-HR-CRISPR","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Ontario Genomics; Genome Canada","keywords":"CRISPR; Biology; Transgenesis; Transgene; Blastocyst; Gene knockin; Gene targeting; Embryo; Genome editing; Genetics; Computational biology; Cell biology; Chromatin; Gene; Embryogenesis; Reproductive technology","score_opus":0.017753603989136776,"score_gpt":0.2736950639411081,"score_spread":0.2559414599519713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766913168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96666014,0.0021151286,0.029660413,0.000022429604,0.00069588,0.00048473064,0.00031828365,0.000039132825,0.000003837278],"genre_scores_gemma":[0.9944439,0.00019085192,0.0047462704,0.00003271856,0.0004138748,0.00006547641,0.000005091429,0.00009328239,0.000008567289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794877,0.00007969313,0.00053853425,0.0007485732,0.00022614146,0.0004582759],"domain_scores_gemma":[0.9978267,0.0000066884727,0.00033859882,0.0013822741,0.00030846256,0.00013726522],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043519423,0.00040438192,0.0004167406,0.00023618691,0.00014036997,0.00007509386,0.0004402469,0.00057044614,0.000010160332],"category_scores_gemma":[0.00023143315,0.00047655366,0.00016094063,0.00013988043,0.0000674548,0.0000048484017,0.00048554802,0.00035678007,0.000004129359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017634604,0.00015572108,0.003780448,0.00014027192,0.000065675435,0.0000065880654,0.000010374656,0.036688615,0.9590383,0.00003057999,0.00006492064,8.281809e-7],"study_design_scores_gemma":[0.0005350958,0.000041220203,0.019689133,0.00012341754,0.0000464888,2.1105365e-8,0.0000028969641,0.039458983,0.9391204,2.0058857e-7,0.00050468236,0.00047746926],"about_ca_topic_score_codex":0.00008857762,"about_ca_topic_score_gemma":0.00003013632,"teacher_disagreement_score":0.027783703,"about_ca_system_score_codex":0.00009035892,"about_ca_system_score_gemma":0.00038684404,"threshold_uncertainty_score":0.9997686},"labels":[],"label_agreement":null},{"id":"W2766955181","doi":"10.1038/nrg.2017.74","title":"Emerging and evolving concepts in gene essentiality","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":312,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canadian Institute for Advanced Research","funders":"","keywords":"Biology; Gene; Computational biology; Context (archaeology); Genetics; Genome; Evolutionary biology","score_opus":0.03533204528761167,"score_gpt":0.4546186408315254,"score_spread":0.41928659554391373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766955181","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00004364702,0.9977102,0.00040197378,0.000009076731,0.0005729679,0.0009190387,0.000036794805,0.000008913935,0.000297336],"genre_scores_gemma":[0.00018061977,0.99628943,0.002105919,0.00004034298,0.00073487597,0.00007962473,0.0002549048,0.00007771624,0.00023656645],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99765843,0.00019706461,0.00079917256,0.00078593375,0.00015668044,0.0004027022],"domain_scores_gemma":[0.99824846,0.000021526546,0.0004244374,0.0011169236,0.000057671456,0.00013096444],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006529232,0.00057643215,0.0016133329,0.000111576956,0.00009820433,0.00008442099,0.0005291573,0.0011901063,0.000013156946],"category_scores_gemma":[0.00033541457,0.0005101646,0.00041353467,0.000118183576,0.00008283565,0.000003291277,0.00038345423,0.0007985123,0.000009178672],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000010482203,0.0000141421015,0.000034043533,0.007815418,0.000051525265,0.000007771458,0.000013152896,0.0000034786403,0.00020483737,0.000005149883,0.0007764688,0.99107295],"study_design_scores_gemma":[0.00014580328,0.00002759244,0.000034546632,0.0043353178,0.0002654734,0.00005711092,0.000002383598,0.000013936841,0.00025749148,0.000006606771,0.9943415,0.0005122651],"about_ca_topic_score_codex":0.0000034157342,"about_ca_topic_score_gemma":0.000031731823,"teacher_disagreement_score":0.993565,"about_ca_system_score_codex":0.000030424675,"about_ca_system_score_gemma":0.00013038988,"threshold_uncertainty_score":0.999735},"labels":[],"label_agreement":null},{"id":"W2767286122","doi":"10.1182/bloodadvances.2017010355","title":"A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1","year":2017,"lang":"en","type":"article","venue":"Blood Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Strain (injury); Phenotype; Knockout mouse; Biology; Genetics; Anatomy; Gene","score_opus":0.006531248503340475,"score_gpt":0.3028832994302317,"score_spread":0.2963520509268912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767286122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897469,0.009039118,0.0008319132,0.000031845975,0.000035124987,0.00007408385,0.000043726384,0.0000038136745,0.00019344826],"genre_scores_gemma":[0.9968376,0.0014745111,0.0014460746,0.000005322357,0.0000163682,0.000007130324,0.000008999542,0.000006157676,0.00019781287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954504,0.000007314274,0.000115041286,0.00016665613,0.000047525013,0.0001184342],"domain_scores_gemma":[0.9997004,0.0000070082933,0.000048119444,0.00020318017,0.000014039618,0.00002722521],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006940256,0.000079411904,0.00009962085,0.000020457994,0.00004105542,0.000014749584,0.000106217696,0.000035755347,0.0000020252144],"category_scores_gemma":[0.000053689437,0.00007619817,0.00002471428,0.00001046392,0.00005298349,0.000005678472,0.000050021947,0.000031659274,2.486407e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001259732,0.00003915337,0.011296186,0.000057373276,0.00001792178,0.0000020905775,0.00008768298,0.0004493693,0.9650883,0.000019737246,0.0000013440738,0.022928212],"study_design_scores_gemma":[0.0008189722,0.0001880279,0.0461826,0.000033522356,0.000014344674,0.000006867624,0.00025698968,0.00018409069,0.94890517,0.0001555274,0.0030849539,0.00016893573],"about_ca_topic_score_codex":0.000012128316,"about_ca_topic_score_gemma":0.00016001308,"teacher_disagreement_score":0.034886416,"about_ca_system_score_codex":0.0000018168938,"about_ca_system_score_gemma":0.000007860116,"threshold_uncertainty_score":0.31072715},"labels":[],"label_agreement":null},{"id":"W2767444421","doi":"10.1093/neuonc/nox168.956","title":"STEM-42. GENOME-WIDE CRISPR SCREENS IN BRAIN TUMOR INITIATING CELLS (BTICS) IDENTIFY POTENT SENSITIZERS OF CONVENTIONAL CHEMORADIOTHERAPY","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"CRISPR; Chemoradiotherapy; Cancer research; Genome editing; Frameshift mutation; Temozolomide; Biology; Medicine; Gene; Mutation; Cancer; Genetics; Glioma","score_opus":0.01719811970316495,"score_gpt":0.328887365967081,"score_spread":0.3116892462639161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767444421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99037933,0.0003107668,0.0060266447,0.00084360334,0.00055336487,0.00028546102,0.000038814313,0.000012747327,0.0015492553],"genre_scores_gemma":[0.99659413,0.00014639022,0.0015115644,0.0013295334,0.00023779448,0.000015217866,0.000034988563,0.000040164014,0.00009020299],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850816,0.000118846336,0.0004470845,0.0004156142,0.00015335645,0.000356943],"domain_scores_gemma":[0.99888515,0.00011280214,0.00029180408,0.00052006886,0.0001003007,0.00008987965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003682264,0.00020131104,0.00037569832,0.00009478522,0.000109239845,0.000029944504,0.00033223382,0.00017996402,0.000028017264],"category_scores_gemma":[0.00017995638,0.00022846242,0.0001438144,0.000047967747,0.00017168002,0.0000074745167,0.00017243109,0.00020510412,0.000006559847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009223372,0.000081351085,0.005067914,0.000045313835,0.000040554514,0.00012061319,0.00009216504,0.0013301068,0.9906651,0.000029177347,0.00086690765,0.0015685749],"study_design_scores_gemma":[0.0022343346,0.00053065066,0.025987659,0.00002248455,0.000022437107,0.000097392905,0.00020731922,0.0006849152,0.9422664,0.000035304907,0.027641838,0.00026923913],"about_ca_topic_score_codex":0.000048597234,"about_ca_topic_score_gemma":0.00008913812,"teacher_disagreement_score":0.048398662,"about_ca_system_score_codex":0.000048540856,"about_ca_system_score_gemma":0.00014533644,"threshold_uncertainty_score":0.9316427},"labels":[],"label_agreement":null},{"id":"W2767673199","doi":"10.1158/1538-8514.synthleth-ia06","title":"Abstract IA06: Leveraging genome-wide CRISPR screens and synthetic lethal interactions for novel cancer therapeutics","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Frizzled; Biology; Wnt signaling pathway; Cancer; Genome editing; Computational biology; Cas9; Genome; Context (archaeology); Cancer research; Genetics; Gene","score_opus":0.040523857169522455,"score_gpt":0.35626202916618976,"score_spread":0.3157381719966673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767673199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6905946,0.013215831,0.29172003,0.0024110205,0.00074168394,0.00059361063,0.00021026906,0.00003747381,0.00047548593],"genre_scores_gemma":[0.9928766,0.0024716544,0.002068155,0.0016331769,0.00032428227,0.00018584315,0.00003395831,0.0001029548,0.00030340586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998554,0.000016048867,0.0002647925,0.0005351144,0.00016272589,0.00046733223],"domain_scores_gemma":[0.9987753,0.00003132274,0.00016661047,0.0007606017,0.0001541944,0.00011195403],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001445206,0.00033545986,0.00024667243,0.00005810342,0.00043967573,0.00017049364,0.00039709822,0.00016153329,0.00002059679],"category_scores_gemma":[0.000023789735,0.00034578083,0.00017083333,0.000036429115,0.00015305585,0.000013139368,0.00014297657,0.00020470207,0.0000012864487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000761785,0.00005615076,0.0018476127,0.00006648081,0.00053220487,0.0000043021278,0.00021532208,0.0022522716,0.97606933,0.000043654192,0.000036861715,0.018799614],"study_design_scores_gemma":[0.0017865616,0.00014794777,0.036740832,0.00012226253,0.00047713047,0.000027884367,0.0002159566,0.0029706005,0.7540295,0.0001402003,0.20243108,0.0009100072],"about_ca_topic_score_codex":0.00021200832,"about_ca_topic_score_gemma":0.00024236547,"teacher_disagreement_score":0.30228198,"about_ca_system_score_codex":0.00005146844,"about_ca_system_score_gemma":0.000106152336,"threshold_uncertainty_score":0.99989945},"labels":[],"label_agreement":null},{"id":"W2767803504","doi":"10.1101/217166","title":"SgTiler: a fast method to design tiling sgRNAs for CRISPR/Cas9 mediated screening","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Princess Margaret Cancer Foundation; Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health","keywords":"CRISPR; Python (programming language); Computer science; Cas9; Endonuclease; Guide RNA; Computational biology; Programming language; Biology; Genetics; DNA; Gene","score_opus":0.025741636648891515,"score_gpt":0.3135152633390783,"score_spread":0.2877736266901868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767803504","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04143835,0.0017508043,0.95361763,0.00019082076,0.0009256567,0.0015373172,0.00036452056,0.00016528476,0.0000095869145],"genre_scores_gemma":[0.6002573,0.00015354696,0.39738572,0.00022711733,0.0011198726,0.00058793,0.000004595758,0.0002372421,0.000026728241],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99658674,0.00014000272,0.0005783257,0.0015082596,0.00031406735,0.0008726137],"domain_scores_gemma":[0.99653476,0.000101927704,0.0003573055,0.0019271022,0.00058316975,0.0004957449],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013761515,0.00076180603,0.00069080957,0.00024491668,0.00032891094,0.00030899202,0.0010648733,0.0008482638,0.00001233288],"category_scores_gemma":[0.0009957607,0.000872365,0.00032395023,0.00015251171,0.000059509257,0.000010197247,0.00087059627,0.00048787237,0.000020490697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012669596,0.000043457447,0.00024933775,0.00024129436,0.0002696757,0.000014360994,0.000011875553,0.009600027,0.98795706,0.000019870422,0.0014003257,0.000066033324],"study_design_scores_gemma":[0.000723486,0.00018858728,0.00262101,0.00032001737,0.00016479283,7.659205e-8,0.0000058226724,0.0070519676,0.9492756,0.0000016085022,0.038551997,0.001094993],"about_ca_topic_score_codex":0.000034405763,"about_ca_topic_score_gemma":0.0000042041725,"teacher_disagreement_score":0.55881894,"about_ca_system_score_codex":0.00006719772,"about_ca_system_score_gemma":0.000421023,"threshold_uncertainty_score":0.9993727},"labels":[],"label_agreement":null},{"id":"W2768045733","doi":"10.1158/1538-8514.synthleth-a38","title":"Abstract A38: Genome-wide CRISPR-Cas9 screens reveal modulators of temozolomide sensitivity in glioblastoma","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Temozolomide; MSH6; CRISPR; Cancer research; Biology; Synthetic lethality; Gene; DNA repair; Medicine; Glioblastoma; Genetics; DNA mismatch repair","score_opus":0.014533477766253739,"score_gpt":0.30992175175134634,"score_spread":0.2953882739850926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768045733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864827,0.002460997,0.009995379,0.0002363661,0.00016424106,0.00022293291,0.000046933506,0.000012362852,0.00037811478],"genre_scores_gemma":[0.9984517,0.0004447757,0.0005258758,0.0003177259,0.00010382513,0.000017244598,0.000011563097,0.00005435854,0.00007293869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986834,0.00003713717,0.0003140338,0.00039805827,0.00019316458,0.0003742209],"domain_scores_gemma":[0.998694,0.00001234588,0.00017910716,0.0009334902,0.00009575008,0.00008527525],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024880876,0.0002518969,0.00028522447,0.00007539874,0.000098717646,0.00003661019,0.00030229357,0.0002047018,0.000010193342],"category_scores_gemma":[0.000038683476,0.00027226802,0.00015540897,0.0000654013,0.00013754536,0.000006946254,0.00015269259,0.0001749176,0.000002706488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010700757,0.000051751216,0.029774565,0.000046888195,0.00013689316,0.00004942069,0.000064239095,0.007904271,0.957684,0.000013461253,0.000025575817,0.00414197],"study_design_scores_gemma":[0.0005575363,0.00009855623,0.23501498,0.000037515252,0.00003736438,0.0000075040193,0.000029607063,0.00040285575,0.7607267,0.00004528955,0.0027681603,0.00027397912],"about_ca_topic_score_codex":0.00027770488,"about_ca_topic_score_gemma":0.0007552479,"teacher_disagreement_score":0.2052404,"about_ca_system_score_codex":0.00003890078,"about_ca_system_score_gemma":0.00008318355,"threshold_uncertainty_score":0.99997294},"labels":[],"label_agreement":null},{"id":"W2768231922","doi":"10.1266/ggs.17-00024","title":"&lt;i&gt;piggyBac&lt;/i&gt;- and phiC31 integrase-mediated transgenesis in &lt;i&gt;Drosophila prolongata&lt;/i&gt;","year":2017,"lang":"en","type":"article","venue":"Genes & Genetic Systems","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science","keywords":"Transgenesis; Biology; Drosophila melanogaster; Integrase; Transformation (genetics); Genetics; Computational biology; Gene; Embryogenesis; Reproductive technology","score_opus":0.010620750781388685,"score_gpt":0.2580009770246781,"score_spread":0.24738022624328943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768231922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9025258,0.09043354,0.0023144584,0.00021749586,0.001655375,0.0014459039,0.0002266518,0.00010120917,0.0010795839],"genre_scores_gemma":[0.98604274,0.0093057975,0.0007170631,0.00007924293,0.0013460327,0.00048222806,0.00029417544,0.00021611377,0.0015166021],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948552,0.00028341572,0.0012239695,0.0016799725,0.0006300929,0.0013273106],"domain_scores_gemma":[0.996431,0.00008165035,0.00043308694,0.002227849,0.00026313248,0.0005632844],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008319667,0.0010054472,0.0010394645,0.00032961712,0.0005032637,0.0003422895,0.0012594591,0.0008855397,0.000042808148],"category_scores_gemma":[0.00023292487,0.0010107729,0.00032782886,0.0002757026,0.00043323266,0.000027085804,0.00040435526,0.00023683633,0.000057501034],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001330462,0.00012774215,0.006405228,0.00037108158,0.0002581514,0.00007684423,0.00026595176,0.0023699563,0.9806966,0.00006480906,0.0016472568,0.007583343],"study_design_scores_gemma":[0.0078080525,0.001514286,0.24324329,0.0008021364,0.00061919674,0.00074626785,0.00021408267,0.010772454,0.21571279,0.00009369428,0.51444215,0.0040315962],"about_ca_topic_score_codex":0.00006722743,"about_ca_topic_score_gemma":0.0012139966,"teacher_disagreement_score":0.76498383,"about_ca_system_score_codex":0.00007897767,"about_ca_system_score_gemma":0.0002496074,"threshold_uncertainty_score":0.99923426},"labels":[],"label_agreement":null},{"id":"W2768494297","doi":"10.1038/nbt.4021","title":"Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency","year":2017,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":297,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Heart, Lung, and Blood Institute","keywords":"Genome editing; Homology directed repair; Cas9; CRISPR; DNA repair; DNA; Biology; Homologous recombination; Gene; DNA damage; Homology (biology); Genome; Computational biology; Genetics; Cell biology; Molecular biology; Nucleotide excision repair","score_opus":0.004062020126763813,"score_gpt":0.26934985040765086,"score_spread":0.26528783028088704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768494297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918764,0.0044871,0.0023401636,0.00039415646,0.00023222264,0.00015575365,0.000035241264,0.00007593559,0.00040302335],"genre_scores_gemma":[0.99774563,0.0005713293,0.0012771877,0.00007088216,0.00019175447,0.000009284695,0.000035761084,0.000019792424,0.00007835448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893767,0.000021577287,0.00022055751,0.0004525565,0.00009953904,0.0002680888],"domain_scores_gemma":[0.99898523,0.00001349657,0.0001695163,0.00071127486,0.00006838722,0.0000521146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020547525,0.00017715865,0.00021345806,0.00013007876,0.0001913639,0.000015906304,0.00026040693,0.0012246046,0.0000067344026],"category_scores_gemma":[0.00062222464,0.00017463428,0.000080004655,0.00005288591,0.00035664474,0.0000051610527,0.00039753303,0.00039868127,0.0000017579358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022801947,0.00004761527,0.0019617584,0.000045937282,0.000037201473,0.000018002109,0.000015890977,0.000015619176,0.99529207,0.00062892615,0.0001263153,0.0017878563],"study_design_scores_gemma":[0.00047630008,0.00032868425,0.014091774,0.000023866256,0.000030860585,0.00014433502,0.00010064959,0.000058214253,0.98054653,0.00015558348,0.0038452528,0.00019795453],"about_ca_topic_score_codex":0.00004522387,"about_ca_topic_score_gemma":0.000071655646,"teacher_disagreement_score":0.01474555,"about_ca_system_score_codex":0.000011818144,"about_ca_system_score_gemma":0.000029201385,"threshold_uncertainty_score":0.94452715},"labels":[],"label_agreement":null},{"id":"W2768540553","doi":"10.2174/1566523217666171121165046","title":"Therapeutic Applications of CRISPR/Cas for Duchenne Muscular Dystrophy","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Dystrophin; Utrophin; CRISPR; Duchenne muscular dystrophy; Exon skipping; Muscular dystrophy; Biology; Genome editing; Exon; Bioinformatics; Medicine; Genetics; Gene; Alternative splicing","score_opus":0.09907920268079923,"score_gpt":0.4626543951073407,"score_spread":0.36357519242654146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768540553","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000036207835,0.8800097,0.117770314,0.0000057762377,0.00040783137,0.0015386672,0.00019843047,0.000012378882,0.000020658683],"genre_scores_gemma":[0.0003411315,0.99580246,0.00062772806,0.000006917334,0.00095184386,0.0012346475,0.0008340505,0.00009242142,0.00010877959],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860835,0.00004197001,0.00044456238,0.00050437264,0.00011560971,0.000285134],"domain_scores_gemma":[0.99820876,0.000019366316,0.00034368597,0.001216187,0.00013179968,0.000080170204],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017128015,0.00040974966,0.00084088,0.00008958253,0.00010660374,0.000029110583,0.0006371647,0.0002568896,0.000009751277],"category_scores_gemma":[0.00001404898,0.00034863356,0.0008164977,0.00006792114,0.00007677433,0.0000019836377,0.000067991445,0.00013551771,0.00000619176],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000119084625,0.00008199165,0.0000010996132,0.0025823794,0.00031520956,1.2853808e-7,0.000011189105,0.00001042967,0.0030337044,0.000037919726,0.00021118842,0.9937028],"study_design_scores_gemma":[0.0003869324,0.00016029929,0.0000035449857,0.00036653507,0.00026160813,0.0000068213226,0.0000021864664,0.000005236123,0.008412214,0.00005603644,0.9899936,0.0003450271],"about_ca_topic_score_codex":0.000001971546,"about_ca_topic_score_gemma":8.9033176e-7,"teacher_disagreement_score":0.99335784,"about_ca_system_score_codex":0.000016939272,"about_ca_system_score_gemma":0.00015973955,"threshold_uncertainty_score":0.9998966},"labels":[],"label_agreement":null},{"id":"W2768625334","doi":"10.1016/b978-0-12-811060-7.00008-5","title":"The Role of Noncoding RNAs in Genome Stability and Aging","year":2017,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Genome; Biology; Transposable element; Chromatin; RNA; Non-coding RNA; Long non-coding RNA; Noncoding DNA; Genetics; Computational biology; RNA splicing; DNA; Gene","score_opus":0.008588127922406541,"score_gpt":0.2590839759362222,"score_spread":0.25049584801381564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768625334","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012291481,0.023422051,0.000012603313,0.000016366414,0.00009554939,0.00024702225,0.00001783545,0.000004399391,0.9638927],"genre_scores_gemma":[0.6604247,0.0020962886,0.0001392087,0.000016087819,0.00025030642,0.000014736108,0.000016542554,0.000052490268,0.3369896],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99926114,0.000010381572,0.00022799548,0.000255765,0.00008329483,0.00016144397],"domain_scores_gemma":[0.99926376,0.000016684127,0.00011635503,0.0005267056,0.000034165634,0.000042340238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027232533,0.0001730505,0.00020533091,0.00002758814,0.000084650484,0.000024354553,0.00020536245,0.00015943947,0.0000051515117],"category_scores_gemma":[0.000024319666,0.0001449026,0.000077092634,0.0000017963308,0.00013393386,9.054687e-7,0.00020099027,0.00015686835,9.4541804e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011219961,0.0000020753466,0.00015997996,0.000053270156,0.000039045113,0.000001943722,0.00012545238,0.0000034258196,0.15210184,0.00025488963,9.0875005e-7,0.84724593],"study_design_scores_gemma":[0.00015622449,0.00004147458,0.00060199026,0.000093338844,0.000021594971,0.0000060941816,0.000026841848,0.00001171792,0.035463996,0.0012286948,0.9621457,0.00020235837],"about_ca_topic_score_codex":0.0000015236056,"about_ca_topic_score_gemma":0.0001310523,"teacher_disagreement_score":0.9621448,"about_ca_system_score_codex":0.000012177559,"about_ca_system_score_gemma":0.00004163085,"threshold_uncertainty_score":0.59089565},"labels":[],"label_agreement":null},{"id":"W2768713198","doi":"10.2174/1566523217666171122094629","title":"CRISPR/Cas9 Gene Editing: From Basic Mechanisms to Improved Strategies for Enhanced Genome Engineering In Vivo","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Cas9; Homologous recombination; Genome; Biology; Computational biology; Genome engineering; Genetics; Gene; Homology directed repair; DNA repair; DNA mismatch repair","score_opus":0.050504660936735,"score_gpt":0.3814422626638076,"score_spread":0.3309376017270726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768713198","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017258086,0.7949791,0.19992347,0.0000060785815,0.0015121127,0.0014158287,0.00039192615,0.000032142234,0.000013559291],"genre_scores_gemma":[0.0017446114,0.9896507,0.0039393078,0.000021105428,0.002495858,0.0010370737,0.000871535,0.00017701328,0.00006279343],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99764925,0.000036068654,0.00060951343,0.000938905,0.00014116561,0.0006250865],"domain_scores_gemma":[0.99849415,0.000029397917,0.00024067357,0.0009764666,0.000079560254,0.0001797598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023142538,0.00072355656,0.0011350102,0.00018130658,0.00008661157,0.00014191245,0.000769719,0.00038248816,0.000025063136],"category_scores_gemma":[0.00004737262,0.0007039159,0.0004932312,0.000096646574,0.000018626837,0.00000808806,0.00015358959,0.00024707627,0.000007469536],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027811691,0.00004377974,1.1145179e-7,0.0008719788,0.000152812,0.0000013535473,0.00006830927,0.0003641578,0.6186576,0.000012790683,0.00010328126,0.37969604],"study_design_scores_gemma":[0.00073225854,0.0002635686,0.0000023989292,0.0006862104,0.00007790769,0.0000031182672,0.000014221998,0.00008058586,0.23499873,0.000054750184,0.7623845,0.0007018017],"about_ca_topic_score_codex":0.000013353848,"about_ca_topic_score_gemma":0.000020525082,"teacher_disagreement_score":0.7622812,"about_ca_system_score_codex":0.00006299823,"about_ca_system_score_gemma":0.0002493106,"threshold_uncertainty_score":0.9995412},"labels":[],"label_agreement":null},{"id":"W2768878686","doi":"10.15252/embr.201745343","title":"The Council of Europe and the prohibition on human germline genome editing","year":2017,"lang":"en","type":"letter","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Germline; Genome; Biology; Genome editing; Genetics; Political science; Computational biology; Gene","score_opus":0.021150983292852518,"score_gpt":0.28638239315316105,"score_spread":0.2652314098603085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768878686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46217367,0.030357657,0.0012516779,0.35459143,0.0069744512,0.004254868,0.0001560884,0.000114333336,0.14012584],"genre_scores_gemma":[0.9044157,0.0008260187,0.000076511285,0.034036417,0.022461519,0.00012227215,0.0008575169,0.00016651112,0.037037525],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988725,0.000042750173,0.00031870842,0.00029877757,0.00029208034,0.00017517451],"domain_scores_gemma":[0.9985228,0.000023529894,0.00042177693,0.0008126084,0.0002006852,0.000018555147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007891134,0.00016911243,0.00018274433,0.000011471556,0.00027565102,0.00005765767,0.00014668153,0.00020073492,0.000003579926],"category_scores_gemma":[0.00034945164,0.00009956294,0.00008313812,0.000015119887,0.00020986231,0.0000011182368,0.00011208935,0.00033832388,7.636747e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005433939,0.000023230452,0.00009614772,0.00031440248,0.0002739959,0.0009824216,0.00029916764,0.00014852997,0.16260216,0.000058280835,0.83361197,0.0015353522],"study_design_scores_gemma":[0.00018260596,0.000068897236,0.00040275612,0.0000483075,0.000037672497,0.00027284445,0.0000040806963,0.000005678851,0.007923485,0.000076166274,0.99085176,0.00012576995],"about_ca_topic_score_codex":0.000017736646,"about_ca_topic_score_gemma":0.000012296199,"teacher_disagreement_score":0.44224206,"about_ca_system_score_codex":0.000019366738,"about_ca_system_score_gemma":0.00014827424,"threshold_uncertainty_score":0.4060059},"labels":[],"label_agreement":null},{"id":"W2769343347","doi":"10.1038/s41467-017-01592-3","title":"A multiplexable TALE-based binary expression system for in vivo cellular interaction studies","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Yale University; National Institutes of Health; Medical Research Council; Princeton University","keywords":"Enhancer; Transgene; Effector; Computational biology; Biology; In vivo; Cell biology; Transcription factor; Activator (genetics); Transcription (linguistics); Genetics; Gene","score_opus":0.02878514806936121,"score_gpt":0.3771592373196088,"score_spread":0.3483740892502476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769343347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94310975,0.040116142,0.011208885,0.0015881592,0.0011000708,0.0011170907,0.00009280637,0.00006580587,0.0016012806],"genre_scores_gemma":[0.99213076,0.00023896153,0.007161734,0.000027764767,0.0000639999,0.00017086056,0.00008091121,0.000013419336,0.000111587025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995471,0.00003085262,0.00012661975,0.00014863942,0.00004324123,0.00010351101],"domain_scores_gemma":[0.9983384,0.00004857777,0.00007887895,0.0014200452,0.00009087905,0.000023199611],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013565262,0.000085259395,0.00009642477,0.000042789587,0.00030801207,0.000027102133,0.00052452384,0.00016635262,9.109874e-7],"category_scores_gemma":[0.0002184779,0.00008181755,0.000055100012,0.000024873521,0.00004795225,0.000005785494,0.00023161375,0.00017304356,8.4307754e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033514934,0.000047061465,0.0010285401,0.00006473426,0.000016621865,4.072849e-7,0.000047870228,0.0012706253,0.99575543,0.00007065505,0.0014888627,0.00017568146],"study_design_scores_gemma":[0.0006204745,0.000050002094,0.0007362662,0.00016033174,0.00001242971,0.0000013196046,0.00044457288,0.008574626,0.93125427,0.0000053543167,0.058020983,0.00011937916],"about_ca_topic_score_codex":0.00000993047,"about_ca_topic_score_gemma":0.00020475994,"teacher_disagreement_score":0.06450117,"about_ca_system_score_codex":0.000028311777,"about_ca_system_score_gemma":0.000019737356,"threshold_uncertainty_score":0.33364227},"labels":[],"label_agreement":null},{"id":"W2770152187","doi":"10.2174/1566523217666171121164132","title":"New Developments in CRISPR/Cas-based Functional Genomics and their Implications for Research Using Zebrafish","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Zebrafish; Functional genomics; Genomics; Computational biology; Biology; Genetics; Computer science; Genome; Gene","score_opus":0.36889615227854183,"score_gpt":0.5229553943083401,"score_spread":0.15405924202979832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770152187","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007634806,0.9375924,0.06029167,0.000022195893,0.0003087365,0.00090178946,0.00010318487,0.0000061566125,0.0000103970715],"genre_scores_gemma":[0.00033638574,0.9955832,0.0023546785,0.000012110125,0.0005690287,0.00020530357,0.0008313575,0.000062239415,0.00004570667],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987093,0.000057589383,0.0003188966,0.00050300546,0.00006433685,0.0003468624],"domain_scores_gemma":[0.99913955,0.000041214487,0.00011305957,0.0004938177,0.000101416,0.000110944246],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039727552,0.000289737,0.0004485638,0.00017328643,0.00019737535,0.000070496775,0.0003097266,0.00021293822,0.00000400116],"category_scores_gemma":[0.00003553681,0.00025520206,0.00016921952,0.00008798892,0.000045156135,0.0000028466006,0.00009712672,0.00019763895,0.000001383403],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018292647,0.00003070234,0.000034983514,0.00047498423,0.000061302744,6.973432e-8,0.0000200117,0.00004073578,0.0053932946,0.000009673754,0.00084762555,0.99306834],"study_design_scores_gemma":[0.00053441885,0.000049782255,0.00028289517,0.00036009095,0.000018423849,0.000007136607,0.0000030524834,0.000036137324,0.00310187,0.00006978639,0.99526244,0.00027398512],"about_ca_topic_score_codex":0.000007279674,"about_ca_topic_score_gemma":0.000014198798,"teacher_disagreement_score":0.9944148,"about_ca_system_score_codex":0.00008323418,"about_ca_system_score_gemma":0.0010105837,"threshold_uncertainty_score":0.99999005},"labels":[],"label_agreement":null},{"id":"W2770623899","doi":"10.1089/aid.2017.0161","title":"Purging Exhausted Virus-Specific CD8 T Cell Phenotypes by Somatic Cell Reprogramming","year":2017,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"UCLA AIDS Institute; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Bill and Melinda Gates Foundation","keywords":"Reprogramming; Biology; KLF4; Cytotoxic T cell; Induced pluripotent stem cell; Somatic cell; clone (Java method); SOX2; T cell; Virology; Cell biology; Immune system; Cell; Immunology; Genetics; In vitro; Gene; Embryonic stem cell","score_opus":0.04030991721227249,"score_gpt":0.3725687123523322,"score_spread":0.3322587951400597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770623899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889029,0.005657332,0.000782305,0.0000345372,0.000059215425,0.0002350524,0.000014842536,0.000027847052,0.0042859237],"genre_scores_gemma":[0.99466854,0.0010974796,0.0006326094,0.000028645902,0.00027254186,0.00003267384,0.00004595376,0.000045239965,0.003176336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981832,0.000059288464,0.00022315021,0.00055709237,0.0003204494,0.00065680186],"domain_scores_gemma":[0.99859184,0.000032360018,0.00007738511,0.0009652183,0.00011531201,0.00021788137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005689437,0.00019644502,0.00019094581,0.000110246925,0.00110963,0.00050063763,0.00048768378,0.00013836217,0.000063791806],"category_scores_gemma":[0.00008494744,0.00019244375,0.00006544202,0.000060982962,0.00031951134,0.000016529395,0.0003789051,0.00027642757,0.000025959125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033870754,0.00009125186,0.021259397,0.00010113015,0.00002053232,0.000008739187,0.000085719614,0.00000473261,0.96818614,0.00007023027,0.0075242063,0.002614075],"study_design_scores_gemma":[0.0006650759,0.0009037355,0.006645093,0.000032429165,0.0000089399055,0.0000031597124,0.00027106097,0.0000067717287,0.8757528,0.00017561959,0.115253136,0.00028218547],"about_ca_topic_score_codex":0.00022288407,"about_ca_topic_score_gemma":0.000050946655,"teacher_disagreement_score":0.10772893,"about_ca_system_score_codex":0.00001810336,"about_ca_system_score_gemma":0.000028980854,"threshold_uncertainty_score":0.8534489},"labels":[],"label_agreement":null},{"id":"W2771920161","doi":"10.1111/pbi.12870","title":"Application of protoplast technology to CRISPR/Cas9 mutagenesis: from single‐cell mutation detection to mutant plant regeneration","year":2017,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":335,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Agricultural Biotechnology Research Center, Academia Sinica; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; Academia Sinica","keywords":"Biology; CRISPR; Mutagenesis; Protoplast; Cas9; Mutant; Genetics; Nicotiana tabacum; DNA; Insertional mutagenesis; Gene; Phytoene desaturase; Transfection; Molecular biology","score_opus":0.007076309430220888,"score_gpt":0.2609948396821039,"score_spread":0.25391853025188305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2771920161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59892666,0.00018392013,0.39918897,0.00094963686,0.00022075535,0.00038472915,0.00009368225,0.00003323029,0.00001839728],"genre_scores_gemma":[0.99105257,0.00011849891,0.008306252,0.000050629405,0.00024569954,0.00010001939,0.00008115543,0.000025937794,0.000019258643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874735,0.00002297566,0.00039209632,0.000405086,0.00014868726,0.00028377684],"domain_scores_gemma":[0.9988257,0.000008785276,0.00032114607,0.0006233882,0.00011516572,0.00010581466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018119205,0.00020009965,0.00021803379,0.00037520524,0.00030842875,0.00005686613,0.00046514085,0.0005539183,0.0000041549642],"category_scores_gemma":[0.00019478038,0.00019981629,0.00005899666,0.00013260808,0.0000675152,0.000010084677,0.00016232145,0.00023664556,0.000015355863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013441025,0.000058996786,0.00055766496,0.000011280458,0.000035606958,0.00001667676,0.000040497922,0.0013001256,0.9557446,0.000022649565,0.00007077351,0.04200672],"study_design_scores_gemma":[0.00042529483,0.00069640257,0.0010705566,0.000033967313,0.000032265445,0.00048281418,0.00013173874,0.001224428,0.98711985,0.000113698385,0.008452724,0.0002162399],"about_ca_topic_score_codex":0.000047875656,"about_ca_topic_score_gemma":0.00031765472,"teacher_disagreement_score":0.39212587,"about_ca_system_score_codex":0.00004307382,"about_ca_system_score_gemma":0.000039424696,"threshold_uncertainty_score":0.8148272},"labels":[],"label_agreement":null},{"id":"W2772961895","doi":"10.1073/pnas.1714640114","title":"Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Howard Hughes Medical Institute","keywords":"CRISPR; Genome editing; Biology; Cas9; Indel; Computational biology; Genetics; Human genome; Genome; Genetic variation; Single-nucleotide polymorphism; Population; Gene; Genotype; Medicine","score_opus":0.032027829642522494,"score_gpt":0.34622144266644755,"score_spread":0.31419361302392507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2772961895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99690366,0.00018978107,0.000026924825,0.0010603283,0.0000129240225,0.00010650171,0.000006239069,0.0000033315923,0.0016903401],"genre_scores_gemma":[0.99874413,0.00006786764,0.0008787455,0.00013453301,0.00009869121,0.00000406426,3.465305e-7,0.000004555227,0.00006707263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914205,0.0000035915027,0.00018333759,0.00023422479,0.00031885956,0.000117924195],"domain_scores_gemma":[0.99959433,0.000012385706,0.00023247361,0.000018902703,0.000112714195,0.000029180514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043306025,0.000079982856,0.00008337081,0.000035335885,0.00041341648,0.00003459713,0.00045851205,0.00007424162,0.0000048266565],"category_scores_gemma":[0.00017452743,0.000059168702,0.0000412506,0.000053467575,0.00039193302,0.000010958279,0.00018726697,0.00006554126,3.9870474e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009383803,0.0000129443715,0.0066089057,0.00001551406,0.000012789096,2.5926634e-9,0.00003839339,0.00013949853,0.9908687,0.0015886925,0.0002492579,0.0004559355],"study_design_scores_gemma":[0.000109050765,0.000055511944,0.426203,0.00001086735,0.0000064737505,0.0000024836966,0.0000150946835,0.00050924066,0.5709049,0.0018011904,0.0003251164,0.00005701777],"about_ca_topic_score_codex":0.0000039948595,"about_ca_topic_score_gemma":1.4836841e-7,"teacher_disagreement_score":0.41996375,"about_ca_system_score_codex":0.000011369374,"about_ca_system_score_gemma":0.0000082246015,"threshold_uncertainty_score":0.3179707},"labels":[],"label_agreement":null},{"id":"W2773124324","doi":"10.1016/j.omtn.2017.11.012","title":"Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canada Research Chairs; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Rare Diseases Clinical Research Network; Rare Disease Foundation; National Center for Advancing Translational Sciences; BC Children’s Hospital Foundation","keywords":"Transcription activator-like effector nuclease; Induced pluripotent stem cell; Arginase; Biology; Effector; Transplantation; Cell biology; Embryonic stem cell; Molecular biology; Genome editing; Cancer research; Gene; Genetics; Arginine; CRISPR; Medicine","score_opus":0.009508594802257408,"score_gpt":0.26875770787647724,"score_spread":0.25924911307421983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2773124324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94456726,0.000975601,0.05353066,0.000027296723,0.00031318358,0.00023246984,0.000066477,0.000012189309,0.00027488547],"genre_scores_gemma":[0.9963611,0.0009802053,0.002337246,0.000051433468,0.000060136008,0.000012251378,0.00007134037,0.000046687626,0.00007962654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885595,0.00004406115,0.00029892277,0.0003328743,0.00022836079,0.0002398206],"domain_scores_gemma":[0.9988673,0.000007425247,0.00019413586,0.0007450163,0.0001162618,0.00006990209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172927,0.00021681213,0.00025323985,0.0000571143,0.00008576883,0.000024379655,0.00042920487,0.00016154592,0.0000111233685],"category_scores_gemma":[0.000012161268,0.00021721802,0.00018978876,0.000050559716,0.00013095813,0.000006558977,0.000042580057,0.00007477193,0.0000020597035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022527951,0.00008861755,0.0004901183,0.0000652548,0.00009717532,0.000008360488,0.00014377577,0.0014599548,0.995103,0.000033376244,0.000016865473,0.0022681984],"study_design_scores_gemma":[0.0011884668,0.00034439642,0.0046576257,0.000018423363,0.0000323938,0.000007346563,0.000038299902,0.0011683166,0.9910128,0.000018775052,0.0012916087,0.00022154696],"about_ca_topic_score_codex":0.00006220556,"about_ca_topic_score_gemma":0.000008126917,"teacher_disagreement_score":0.051793836,"about_ca_system_score_codex":0.000008265999,"about_ca_system_score_gemma":0.000040544015,"threshold_uncertainty_score":0.8857894},"labels":[],"label_agreement":null},{"id":"W2773472223","doi":"","title":"Development of Site-Specific CFTR Gene Integration Tools for Testing Gene Editing in Pig Cells","year":2017,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Transgene; Biology; Gene; Cystic fibrosis transmembrane conductance regulator; Genome editing; Gene delivery; Gene targeting; Computational biology; Genetics; Genome engineering; Genetic enhancement; Reporter gene; Molecular biology; Gene expression","score_opus":0.02289882229750397,"score_gpt":0.27962772357020227,"score_spread":0.2567289012726983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2773472223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781407,0.0012703409,0.014541927,0.0000071579307,0.00033024367,0.0003129408,0.000042646418,0.000007514054,0.005346491],"genre_scores_gemma":[0.8850253,0.0002823236,0.11007312,0.0000014007333,0.00014667648,0.0000020534576,0.0014127413,0.000023451646,0.0030329137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928486,0.000010798616,0.00016232379,0.0002738001,0.00010605709,0.00016216986],"domain_scores_gemma":[0.9992188,0.000021257854,0.00029959832,0.00024417148,0.0001778088,0.00003835177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014902759,0.00016074009,0.00024377684,0.000038169816,0.000103109385,0.000013310789,0.00022508884,0.00023096186,0.000094355724],"category_scores_gemma":[0.00006183621,0.00021680196,0.00008710718,0.00001963511,0.000020628462,0.000012974806,0.000040191393,0.00006475728,9.2320863e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007693234,0.000021829539,0.000033614746,0.00012141102,0.000025172294,0.0000011097412,0.0028058905,0.00015592591,0.8843865,0.0000031595534,0.00009373107,0.11227472],"study_design_scores_gemma":[0.000526537,0.00009184636,0.0244986,0.00017211131,0.0000317411,5.9877686e-7,0.007485281,0.00022608423,0.9629438,0.0000012344944,0.0037804632,0.00024173794],"about_ca_topic_score_codex":0.0017942104,"about_ca_topic_score_gemma":0.03486621,"teacher_disagreement_score":0.11203299,"about_ca_system_score_codex":0.00007762228,"about_ca_system_score_gemma":0.000111927926,"threshold_uncertainty_score":0.982745},"labels":[],"label_agreement":null},{"id":"W2773954796","doi":"10.1126/science.aap9026","title":"Principles for gene drive research","year":2017,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Gene; Gene drive; Political science; Computational biology; Biology; Genetics","score_opus":0.07951527555894737,"score_gpt":0.46392168972745707,"score_spread":0.3844064141685097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2773954796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9799527,0.00023670155,0.014947648,0.00020931795,0.0002283023,0.00015617674,0.0000056970703,0.000004787614,0.0042586736],"genre_scores_gemma":[0.9920304,0.000036543574,0.0062103076,0.000014210156,0.0001703443,0.000019093412,0.000002042805,0.000004515217,0.0015125704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993256,0.000004054243,0.000051410378,0.00023498203,0.00014386752,0.00024012543],"domain_scores_gemma":[0.999266,0.0000060409443,0.000018367615,0.0005071502,0.00014340825,0.000059015063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007752707,0.000037621056,0.00003275142,0.00002947138,0.00061941927,0.00009449762,0.0005749086,0.000025905361,0.0000020950984],"category_scores_gemma":[0.0005957497,0.00003420584,0.0000200725,0.000036337937,0.0004239601,0.0000033299411,0.00025124225,0.00003205793,0.000005009729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038454477,0.000004283028,0.00077982806,0.0000032123726,0.0000012672576,2.6197026e-7,0.000022752532,0.00008940448,0.9964338,0.00040188807,0.00010233365,0.0021571117],"study_design_scores_gemma":[0.000091514434,0.00006779729,0.01895675,0.0000029452585,7.591166e-7,0.0000019492095,0.000020888043,0.00045333395,0.916649,0.00011319244,0.06359128,0.000050621555],"about_ca_topic_score_codex":0.0000048932693,"about_ca_topic_score_gemma":0.000013798637,"teacher_disagreement_score":0.07978485,"about_ca_system_score_codex":0.0000069176967,"about_ca_system_score_gemma":0.00009914348,"threshold_uncertainty_score":0.4764135},"labels":[],"label_agreement":null},{"id":"W2774709934","doi":"10.24870/cjb.2017-a213","title":"Leveraging OncoMD to identify synthetic lethal interactions between recurrently mutated genes","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genetics; Gene; Biology; Computational biology","score_opus":0.02311497833936273,"score_gpt":0.3494266839715272,"score_spread":0.3263117056321645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2774709934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9797885,0.0007428494,0.01443966,0.0037563154,0.00097309187,0.000068039524,0.00001814864,0.0000068675095,0.00020652512],"genre_scores_gemma":[0.9985958,0.000057354973,0.0008501989,0.0000496555,0.00029902215,0.000001851863,0.000006151482,0.00001830475,0.00012166217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919015,0.000019223808,0.00025951228,0.00017661651,0.000059210633,0.00029530734],"domain_scores_gemma":[0.9989833,0.000008785294,0.0001602293,0.00044006348,0.000091805094,0.00031581544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638052,0.00012177282,0.00018228433,0.00031958122,0.00024037158,0.00007441869,0.00058508274,0.00019558512,0.000025692854],"category_scores_gemma":[0.0002958638,0.0001283249,0.000092653776,0.000060531183,0.000117296484,0.0000069193693,0.00006836457,0.00026837262,0.0000149390125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015197747,0.00001163997,0.009120831,0.000015742691,0.0002057881,0.00019057764,0.00018351698,0.00037722738,0.8407007,0.000052522144,0.002322495,0.1468038],"study_design_scores_gemma":[0.00030879647,0.00024375127,0.020458216,0.00008647658,0.000050467876,0.0006187886,0.00020112924,0.000020137742,0.8313565,0.000103158935,0.14631692,0.00023561205],"about_ca_topic_score_codex":0.0007939128,"about_ca_topic_score_gemma":0.0043049073,"teacher_disagreement_score":0.14656818,"about_ca_system_score_codex":0.000046271438,"about_ca_system_score_gemma":0.0002489919,"threshold_uncertainty_score":0.52329373},"labels":[],"label_agreement":null},{"id":"W2774801279","doi":"10.1038/npp.2017.197","title":"The Promise of Genome Editing for Modeling Psychiatric Disorders","year":2017,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Genome editing; Psychology; Psychiatry; MEDLINE; Computational biology; Genome; Genetics; Biology; Gene","score_opus":0.010633009548632028,"score_gpt":0.3362518035241658,"score_spread":0.3256187939755337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2774801279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9637508,0.0012418503,0.029702011,0.0010334306,0.002524547,0.0005312438,0.000016133541,0.000012221149,0.0011877905],"genre_scores_gemma":[0.99736536,0.000849614,0.00060032617,0.00009854323,0.000808174,0.0000785296,0.000006544657,0.000027391678,0.00016553536],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992406,0.000022179618,0.00019625717,0.00024247706,0.00005514056,0.000243366],"domain_scores_gemma":[0.9993567,0.000020387559,0.00012224141,0.000396333,0.000057202826,0.00004713609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015659955,0.00010864372,0.00009982452,0.000023141683,0.0004136209,0.00002324479,0.00044177196,0.000064021784,0.0000038644343],"category_scores_gemma":[0.00010028547,0.00009101663,0.00009973921,0.000022146733,0.00007819152,0.0000025506522,0.00008449937,0.0000791666,0.0000012611421],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023383436,0.000039021008,0.00050627487,0.000035035777,0.000046638088,3.772916e-7,0.000021474327,0.011900196,0.97775316,0.000052812513,0.000913779,0.008497376],"study_design_scores_gemma":[0.019214008,0.0036378026,0.030148683,0.000025413872,0.0004912063,0.000056537312,0.00024645435,0.27330866,0.14366096,0.0025814334,0.52497184,0.0016569641],"about_ca_topic_score_codex":0.000003473372,"about_ca_topic_score_gemma":0.000013034574,"teacher_disagreement_score":0.8340922,"about_ca_system_score_codex":0.0000026074138,"about_ca_system_score_gemma":0.000022855122,"threshold_uncertainty_score":0.37115505},"labels":[],"label_agreement":null},{"id":"W2774846165","doi":"10.12688/gatesopenres.12771.1","title":"Informed consent in field trials of gene-drive mosquitoes","year":2017,"lang":"en","type":"preprint","venue":"Gates Open Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"Bill and Melinda Gates Foundation","keywords":"Informed consent; Population; Gene drive; Clinical trial; Field (mathematics); Bioethics; Psychology; Engineering ethics; Political science; Medicine; Law; Environmental health; Alternative medicine; Biology; Engineering; Pathology; Genetics","score_opus":0.22604274977358346,"score_gpt":0.5428108801447825,"score_spread":0.31676813037119905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2774846165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96988314,0.0044394904,0.00042321775,0.0009085658,0.0005059395,0.0027973787,0.00019136422,0.0000064388,0.020844486],"genre_scores_gemma":[0.9892736,0.0062346454,0.0016251702,0.000027418337,0.00022450215,0.00027476222,0.0002546141,0.000024577152,0.0020607046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99796647,0.00028518034,0.0006174635,0.00044529833,0.00029533415,0.000390255],"domain_scores_gemma":[0.9977247,0.0006321942,0.00019636292,0.001107474,0.00024789997,0.000091333044],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.003519619,0.00017974,0.0005742855,0.00016286054,0.00007141373,0.00018558085,0.0016234999,0.000416593,0.000075237636],"category_scores_gemma":[0.00877188,0.00016308895,0.00014429068,0.00005226251,0.00013493552,0.0000033063322,0.0034315356,0.00047251882,0.000010573129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097181957,0.00019200609,0.012050342,0.0017436197,0.00044048592,0.00004072833,0.0007550015,0.0043521808,0.9355642,0.00021210183,0.029993262,0.013684226],"study_design_scores_gemma":[0.0008058775,0.00023549047,0.0032018435,0.0004579454,0.000011246263,0.0000030793708,0.00020454185,0.00010196141,0.9831702,0.0005719645,0.011012369,0.00022349432],"about_ca_topic_score_codex":0.0019334571,"about_ca_topic_score_gemma":0.0029155766,"teacher_disagreement_score":0.04760596,"about_ca_system_score_codex":0.00002544475,"about_ca_system_score_gemma":0.0013591294,"threshold_uncertainty_score":0.99957764},"labels":[],"label_agreement":null},{"id":"W2775017129","doi":"10.3390/ijms18122565","title":"Applications of Alternative Nucleases in the Age of CRISPR/Cas9","year":2017,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Transcription activator-like effector nuclease; Genome editing; CRISPR; Zinc finger nuclease; Cas9; Nuclease; Biology; Palindrome; Computational biology; Genome; Genetics; Genome engineering; DNA; Gene","score_opus":0.043847789230520226,"score_gpt":0.4336585506667237,"score_spread":0.38981076143620347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2775017129","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007838542,0.9815721,0.016391575,0.00004926092,0.00024003799,0.00016127343,0.00002984237,5.5191384e-7,0.00077151076],"genre_scores_gemma":[0.06690814,0.9319219,0.0009192273,0.00002744665,0.00017706228,0.000009736323,0.000012384164,0.000008392241,0.000015679985],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99869186,0.00007581394,0.00053421967,0.00014036056,0.00047080667,0.00008692194],"domain_scores_gemma":[0.99869365,0.00004547858,0.00079902064,0.00021643334,0.00022453548,0.00002086244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000581291,0.00012079738,0.00036540828,0.00022047183,0.000025718766,0.00003707376,0.0018933531,0.00007002459,0.0000045034785],"category_scores_gemma":[0.00015763855,0.00008063447,0.00032589544,0.00009680376,0.000255785,0.000006672241,0.00011568883,0.00011980298,5.6470884e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014129287,0.00018309994,0.000052718933,0.0005502393,0.00042358728,0.000121048746,0.00019574161,0.0007231347,0.0058164247,0.0010279904,0.00015665541,0.99073523],"study_design_scores_gemma":[0.00019135118,0.00021906284,0.00004626227,0.0016400731,0.00011936119,0.00025452877,0.00011678444,0.000011143111,0.007404955,0.00031377416,0.9895437,0.00013904845],"about_ca_topic_score_codex":0.000019303716,"about_ca_topic_score_gemma":0.0000073791607,"teacher_disagreement_score":0.9905962,"about_ca_system_score_codex":0.00001072486,"about_ca_system_score_gemma":0.00019313907,"threshold_uncertainty_score":0.35183525},"labels":[],"label_agreement":null},{"id":"W2775363837","doi":"10.1128/mbio.01751-17","title":"Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein","year":2017,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Ministère de l’Éducation, Gouvernement de l’Ontario; Scheme for Promotion of Academic and Research Collaboration; Canadian Institutes of Health Research; Hospital for Sick Children; Government of Canada","keywords":"CRISPR; Trans-activating crRNA; Biology; Nuclease; CRISPR interference; Plasmid; Bacteriophage; Gene; Cas9; Helicase; Mobile genetic elements; Repressor; Genetics; Computational biology; RNA; Gene expression; Escherichia coli","score_opus":0.010062731520186085,"score_gpt":0.30246221336571555,"score_spread":0.29239948184552944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2775363837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99146444,0.00028652002,0.0062732524,0.00022681161,0.00015820339,0.0002505824,0.000011256985,0.000028255752,0.0013006546],"genre_scores_gemma":[0.9964773,0.000038620045,0.0020133872,0.00008663936,0.00024674536,0.000018198014,0.000029853982,0.000041936433,0.0010472863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990929,0.00001483665,0.00013829411,0.0003530012,0.00010882564,0.00029217664],"domain_scores_gemma":[0.9989473,0.0000025700442,0.00007656103,0.0007858984,0.00007064598,0.000117001895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009003193,0.00018578582,0.00015731805,0.000026472077,0.00023940127,0.00014724572,0.0003083017,0.00010737619,0.000048532096],"category_scores_gemma":[0.00009737462,0.00016201042,0.000056994657,0.000039777296,0.00008663408,0.00000816189,0.00014516686,0.00010172226,0.00004112456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107912194,0.00005028705,0.0035902846,0.00004366763,0.000045559358,0.000030337525,0.0000598689,0.000058797716,0.99423844,0.000023156319,0.0004946403,0.0012570452],"study_design_scores_gemma":[0.0008587399,0.0003502789,0.027802654,0.00006718734,0.00003144883,0.000030558826,0.000052530468,0.0002556024,0.95227045,0.000017749917,0.017899001,0.00036378612],"about_ca_topic_score_codex":0.000064208834,"about_ca_topic_score_gemma":0.000054396067,"teacher_disagreement_score":0.04196798,"about_ca_system_score_codex":0.000009682357,"about_ca_system_score_gemma":0.000046039644,"threshold_uncertainty_score":0.6606593},"labels":[],"label_agreement":null},{"id":"W2778853949","doi":"10.1172/jci.insight.96560","title":"Targeting and silencing of rhodopsin by ectopic expression of the transcription factor KLF15","year":2017,"lang":"en","type":"article","venue":"JCI Insight","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; European Research Council; Fondazione Telethon","keywords":"Ectopic expression; Biology; Gene silencing; Transcription factor; Gene; Genetics; Gene expression; Retinitis pigmentosa; Cell biology; Regulation of gene expression","score_opus":0.009673822414378856,"score_gpt":0.26863261525789156,"score_spread":0.2589587928435127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2778853949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99524325,0.0014926937,0.002741503,0.000029684852,0.00012802621,0.00006352795,0.000010443029,0.0000020554141,0.00028878936],"genre_scores_gemma":[0.99940777,0.00015166847,0.0002542209,0.000008588484,0.000046246154,0.0000018068959,0.000004724864,0.000006298737,0.000118668],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996424,0.000013870443,0.000112415495,0.000104334074,0.000058998754,0.00006799939],"domain_scores_gemma":[0.9996505,0.000004466936,0.00007870373,0.00022563897,0.00002255402,0.000018146546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000039642804,0.000059514125,0.00007704758,0.000008694458,0.00007124083,0.000008234345,0.000113185706,0.00006108687,0.000006564976],"category_scores_gemma":[0.000050635805,0.000042381344,0.000034817698,0.000010111823,0.00004241692,0.0000033916492,0.000051108404,0.000037633847,9.829714e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000056538624,0.000008670825,0.0030716287,0.000034353765,0.00000451268,6.984535e-8,0.00021133765,0.000031429914,0.9956332,0.0000042333927,0.00018968737,0.0008052181],"study_design_scores_gemma":[0.00017004083,0.000035209312,0.016059048,0.00003475203,0.0000051085267,6.081023e-7,0.000037629346,0.000066804656,0.9809129,0.000007154208,0.0026211108,0.00004958789],"about_ca_topic_score_codex":0.000021208067,"about_ca_topic_score_gemma":0.0000045828015,"teacher_disagreement_score":0.014720258,"about_ca_system_score_codex":0.0000022646814,"about_ca_system_score_gemma":0.000008476484,"threshold_uncertainty_score":0.1728261},"labels":[],"label_agreement":null},{"id":"W2781785051","doi":"10.3390/biomedicines6010001","title":"Skipping Multiple Exons to Treat DMD—Promises and Challenges","year":2018,"lang":"en","type":"review","venue":"Biomedicines","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; University of Alberta; Women and Children's Health Research Institute; Children's Health Research Institute; Muscular Dystrophy Canada; Canadian Institutes of Health Research; Parent Project Muscular Dystrophy","keywords":"Exon skipping; Exon; Duchenne muscular dystrophy; Medicine; Bioinformatics; Muscular dystrophy; Computational biology; Pharmacology; Biology; Genetics; Gene; Internal medicine; Alternative splicing","score_opus":0.06896496417085068,"score_gpt":0.3780366884314863,"score_spread":0.3090717242606356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781785051","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021843091,0.99822384,0.00028881428,0.00011052942,0.00034694496,0.00040471958,0.000034564568,0.000025005898,0.00034716178],"genre_scores_gemma":[0.0001554901,0.99655753,0.00054143614,0.000037466918,0.0017986406,0.000087487155,0.00012298672,0.000053324064,0.0006456472],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988233,0.00002779167,0.00026938165,0.0005260003,0.00009245286,0.0002610864],"domain_scores_gemma":[0.9992913,0.000035202505,0.00006228847,0.00039390704,0.000040948835,0.00017637905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011512065,0.00035074825,0.0006325498,0.00015922509,0.000053211254,0.000015484158,0.00017557693,0.00026425612,0.000008298571],"category_scores_gemma":[0.00014308303,0.0002655235,0.00012511849,0.00010780499,0.000093976436,0.0000012023003,0.00016273516,0.00005915774,0.00001896204],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005512328,0.000017585602,0.000004146093,0.007665765,0.000082445345,0.000004689123,0.000065856526,1.4044684e-7,0.0016399167,0.0000027921744,0.0034451152,0.98706603],"study_design_scores_gemma":[0.00018877465,0.00028469102,0.000018853638,0.0026534991,0.00019153696,0.000060167295,0.00004743866,0.0000011596577,0.00053855573,0.0000014621157,0.9957162,0.0002976322],"about_ca_topic_score_codex":0.0000090685,"about_ca_topic_score_gemma":0.000021283837,"teacher_disagreement_score":0.9922711,"about_ca_system_score_codex":0.000009931617,"about_ca_system_score_gemma":0.000045302382,"threshold_uncertainty_score":0.9999797},"labels":[],"label_agreement":null},{"id":"W2781815848","doi":"10.1016/j.stemcr.2017.12.004","title":"Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection","year":2018,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; Division of Chemical, Bioengineering, Environmental, and Transport Systems; National Human Genome Research Institute; National Eye Institute; National Science Foundation of Sri Lanka; Research to Prevent Blindness; VitreoRetinal Surgery Foundation; National Institute of General Medical Sciences; John Merck Fund; Waisman Center; Brain and Behavior Research Foundation; University of Wisconsin-Madison; Brain Research Foundation; Burroughs Wellcome Fund; Foundation Fighting Blindness; National Institutes of Health; National Science Foundation","keywords":"Biology; Induced pluripotent stem cell; CRISPR; Genome editing; Cas9; Puromycin; Genome; Computational biology; Gene; Genetics; Cell sorting; Embryonic stem cell; Cell; Protein biosynthesis","score_opus":0.006425518078481189,"score_gpt":0.2408215437813149,"score_spread":0.23439602570283372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781815848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97502494,0.0004511015,0.021751443,0.0000050493227,0.0005545796,0.00021531472,0.0000037872117,0.000020348249,0.0019734353],"genre_scores_gemma":[0.99807125,0.000018305314,0.00022527769,0.000010230062,0.00054276735,0.000010621792,0.000018564151,0.000031067124,0.0010719316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872327,0.000025049569,0.00043789623,0.00038475468,0.00017738859,0.00025161708],"domain_scores_gemma":[0.9992613,0.0000027100705,0.00019574926,0.0003174837,0.00013839857,0.000084355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002261606,0.00015958311,0.00017466125,0.00005100959,0.000085874344,0.000013192244,0.00007821373,0.00011559492,0.00001908371],"category_scores_gemma":[9.4562176e-7,0.00016523123,0.00010673235,0.00008958838,0.000047137117,0.0000027591386,0.000045697514,0.00006601165,0.0000027848887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000068057534,0.000035995417,0.0003813673,0.00008197725,0.000023056287,0.000017754908,0.00017606532,0.000726127,0.99687696,9.2985834e-7,0.00012376618,0.0015492056],"study_design_scores_gemma":[0.0001387415,0.00032937396,0.0009710694,0.00001822251,0.000028840466,0.000092449285,0.00013204223,0.00009807141,0.99197876,0.0000034824045,0.006045765,0.00016318183],"about_ca_topic_score_codex":0.00002276642,"about_ca_topic_score_gemma":0.000025234307,"teacher_disagreement_score":0.023046294,"about_ca_system_score_codex":0.000020165118,"about_ca_system_score_gemma":0.0000314052,"threshold_uncertainty_score":0.67379344},"labels":[],"label_agreement":null},{"id":"W2782913153","doi":"10.1111/pbi.12886","title":"Verification of <scp>DNA</scp> motifs <i>in Arabidopsis</i> using <scp>CRISPR</scp>/Cas9‐mediated mutagenesis","year":2018,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"National Institute of General Medical Sciences; Agriculture and Agri-Food Canada; National Institutes of Health; Recruitment Program of Global Experts; Arizona Biomedical Research Commission; China Scholarship Council","keywords":"Biology; Chromatin; Chromatin immunoprecipitation; DNA; Arabidopsis; Sequence motif; Genetics; CRISPR; Gene; Computational biology; RNA; DNA sequencing; Cas9; Gene expression; Mutant; Promoter","score_opus":0.011021520071036012,"score_gpt":0.25981499745532577,"score_spread":0.24879347738428975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2782913153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9722733,0.0024110791,0.024326922,0.00008424267,0.00046370763,0.00014127306,0.00007325396,0.000039633527,0.00018660001],"genre_scores_gemma":[0.994241,0.0018267619,0.0033236286,0.00007122571,0.0003347306,0.000005355661,0.00007487436,0.0000384469,0.00008398133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982806,0.00006294108,0.00054190616,0.0003949001,0.00018366976,0.0005359833],"domain_scores_gemma":[0.9989901,0.000068279565,0.00028205177,0.0004180178,0.00012686066,0.00011467018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040986235,0.00026018094,0.00031631003,0.00038618568,0.00012225632,0.000025696732,0.00042278052,0.000748836,0.000006102747],"category_scores_gemma":[0.00065131305,0.00026036584,0.000111378984,0.00038045004,0.00025468416,0.000009442961,0.00012010704,0.00039142062,0.000015623691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008602263,0.000071442395,0.003961178,0.000021655045,0.00007661985,0.000028700959,0.000103015314,0.00043337882,0.9932186,0.000026449005,0.0010489296,0.0010014529],"study_design_scores_gemma":[0.00059584336,0.00026774933,0.004044571,0.000050125527,0.000042798398,0.0008469977,0.00042163034,0.0021200727,0.97037184,0.00004832396,0.021120893,0.000069147434],"about_ca_topic_score_codex":0.00002173295,"about_ca_topic_score_gemma":0.000037149683,"teacher_disagreement_score":0.022846729,"about_ca_system_score_codex":0.000039029477,"about_ca_system_score_gemma":0.0001019383,"threshold_uncertainty_score":0.99998486},"labels":[],"label_agreement":null},{"id":"W2783642298","doi":"10.1101/237313","title":"Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Gene; Biology; Computational biology; Genome; Genetics; Promoter; MALAT1; Coding region; Untranslated region; Enhancer; Long non-coding RNA; RNA; Gene expression","score_opus":0.008239742007242366,"score_gpt":0.25390887295335207,"score_spread":0.2456691309461097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783642298","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99276733,0.0014494545,0.004893531,0.00007683543,0.00023713477,0.0002776728,0.0002838755,0.000011912824,0.0000022214442],"genre_scores_gemma":[0.9964195,0.002809406,0.00044559466,0.00001818007,0.0001810341,0.00006470877,0.000005912778,0.00004454267,0.000011154791],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99895215,0.000018569326,0.00024293081,0.00048453186,0.000093677074,0.00020811288],"domain_scores_gemma":[0.9991961,0.000007209264,0.00020511924,0.00043023415,0.00009284616,0.00006847062],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013337833,0.00024352752,0.00028149615,0.00013291051,0.00008430797,0.00011539971,0.00015868839,0.0002451414,0.0000015084793],"category_scores_gemma":[0.000031956228,0.0002749108,0.000044390334,0.00006332792,0.00010561132,0.000020166246,0.0003285234,0.00016580494,2.9080903e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009274836,0.000015182583,0.06734799,0.0002445244,0.000042799653,0.0000035557305,0.000038613583,0.00012466499,0.93214554,0.000013631295,0.0000034312172,0.000010816101],"study_design_scores_gemma":[0.00020568747,0.0000132433815,0.51397294,0.00021935126,0.00003148914,1.44263925e-8,0.000005009461,0.00051451445,0.48467478,3.27461e-7,0.00015283005,0.0002098244],"about_ca_topic_score_codex":0.000058762475,"about_ca_topic_score_gemma":0.000016682581,"teacher_disagreement_score":0.44747075,"about_ca_system_score_codex":0.0000285968,"about_ca_system_score_gemma":0.00011171332,"threshold_uncertainty_score":0.9999703},"labels":[],"label_agreement":null},{"id":"W2783777211","doi":"10.1016/j.devcel.2017.12.007","title":"Ribosomal Protein S12e Has a Distinct Function in Cell Competition","year":2018,"lang":"en","type":"article","venue":"Developmental Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Cancer Institute, Cairo University; National Institutes of Health","keywords":"Biology; Haploinsufficiency; Ribosomal protein; Mutant; Cell; Genetics; Mutation; Cell biology; Gene; Phenotype; RNA; Ribosome","score_opus":0.007530501943727526,"score_gpt":0.22659503180621193,"score_spread":0.2190645298624844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783777211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762975,0.00010018462,0.0086820815,0.00002079662,0.00014701538,0.00018968312,0.000005810932,0.00001490658,0.014542008],"genre_scores_gemma":[0.9951719,0.0000040906916,0.003211354,0.000052330768,0.0001524578,0.00003023502,0.0001697242,0.000016487935,0.0011914071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993228,0.00001559353,0.00014794897,0.00023830312,0.00008248403,0.00019290402],"domain_scores_gemma":[0.99980634,0.0000020570035,0.000026775546,0.00009245808,0.000024804633,0.000047553698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069572765,0.00011871373,0.00007187472,0.000040164436,0.00006729158,0.000020728858,0.00007536787,0.000077958866,0.000099985824],"category_scores_gemma":[0.000005639668,0.00012656876,0.000027130915,0.000081387734,0.000048831524,0.0000029333348,0.000068509915,0.000058112924,0.00010868823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005704955,0.00006914173,0.004698606,0.000028627908,0.0000037720442,0.0000028220707,0.000106368716,0.000009976634,0.99398637,0.00000951444,0.00036642008,0.0006613336],"study_design_scores_gemma":[0.0005831331,0.00020255352,0.030529303,0.000014894081,0.000003100654,0.000005688566,0.00011728912,0.000059350103,0.93769765,0.00002561024,0.030571016,0.00019040167],"about_ca_topic_score_codex":0.000019610814,"about_ca_topic_score_gemma":0.00014901302,"teacher_disagreement_score":0.056288708,"about_ca_system_score_codex":0.000029448258,"about_ca_system_score_gemma":0.000064872685,"threshold_uncertainty_score":0.5161324},"labels":[],"label_agreement":null},{"id":"W2784203523","doi":"10.1038/s10038-017-0400-0","title":"A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping","year":2018,"lang":"en","type":"article","venue":"Journal of Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"","keywords":"Exon skipping; Duchenne muscular dystrophy; Exon; CRISPR; Morpholino; Genome editing; Dystrophin; RNA splicing; mdx mouse; Cas9; Biology; Muscular dystrophy; HEK 293 cells; Gene; Molecular biology; Alternative splicing; Genetics; RNA; Gene knockdown","score_opus":0.02245604092114683,"score_gpt":0.318720431392756,"score_spread":0.2962643904716092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784203523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9811342,0.0025620174,0.015936822,0.0000097112425,0.00007074328,0.00014029037,0.00003130183,0.0000029579242,0.00011198455],"genre_scores_gemma":[0.9959382,0.00025478116,0.0035221137,0.000013711588,0.00017871684,0.0000015105169,0.00003017015,0.000030722545,0.000030115918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998563,0.000051160372,0.0006192735,0.00019432291,0.00038156766,0.00019066171],"domain_scores_gemma":[0.9982391,0.000009166093,0.0004519959,0.0002647323,0.0009342379,0.00010075377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005300389,0.00017301732,0.00029010104,0.00012344097,0.00006978237,0.000014166753,0.00016260294,0.00015002221,0.000014331573],"category_scores_gemma":[0.00005464278,0.00017244658,0.00011057736,0.00008710711,0.00014587565,0.0000059290164,0.00007001082,0.0001076979,2.8753792e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021530304,0.00013472945,0.00028867894,0.00006138375,0.00007520084,8.4971e-7,0.00022270514,0.006542607,0.99201864,0.0000029469804,0.00027543513,0.0003553165],"study_design_scores_gemma":[0.0019523111,0.0011685737,0.004056585,0.00005626869,0.00024208365,0.000018598495,0.00013162324,0.01999395,0.97201073,0.000043238888,0.00015011578,0.00017594385],"about_ca_topic_score_codex":0.0000120752375,"about_ca_topic_score_gemma":0.000010878199,"teacher_disagreement_score":0.020007908,"about_ca_system_score_codex":0.000017155262,"about_ca_system_score_gemma":0.00006961894,"threshold_uncertainty_score":0.70321673},"labels":[],"label_agreement":null},{"id":"W2784476961","doi":"10.1146/annurev-genom-083117-021552","title":"The Genomic Commons","year":2018,"lang":"en","type":"review","venue":"Annual Review of Genomics and Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Commons; Genomics; Intellectual property; Data science; Bureaucracy; Corporate governance; Political science; Biology; Computer science; Business; Genome; Law; Genetics","score_opus":0.017439868905247367,"score_gpt":0.3539630672440992,"score_spread":0.33652319833885186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784476961","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016350488,0.9981703,0.00005638417,0.000016547134,0.00017618672,0.0006327962,0.00020518659,0.000004898637,0.000574174],"genre_scores_gemma":[0.00003516759,0.9982983,0.00022640613,0.00008585887,0.00053699466,0.00003858762,0.00022493962,0.000078041434,0.00047572333],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982482,0.00009035599,0.00083087466,0.00040845588,0.00011610275,0.00030596307],"domain_scores_gemma":[0.99846417,0.000037863396,0.0003815827,0.0008673367,0.00013859732,0.00011043934],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048263415,0.00039858287,0.00094082975,0.00004071655,0.00023257603,0.00003407929,0.00059923844,0.00022237003,0.000007818087],"category_scores_gemma":[0.00003723009,0.00029126767,0.0004198272,0.00007095477,0.00028711915,0.0000010471787,0.00049976545,0.00016897295,0.000011499846],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033236565,0.000031089046,0.0000050405624,0.058076534,0.00043844836,0.0000014672793,0.00005082637,0.0000011611688,0.00023098353,0.0004471797,0.019493492,0.9212205],"study_design_scores_gemma":[0.00006500592,0.00022063815,0.000013498094,0.00717118,0.0004933104,0.000032234573,0.000012738682,6.091079e-7,0.000039772556,0.000030908945,0.9916089,0.00031119687],"about_ca_topic_score_codex":0.0000038589105,"about_ca_topic_score_gemma":0.000036902293,"teacher_disagreement_score":0.9721154,"about_ca_system_score_codex":0.000018308669,"about_ca_system_score_gemma":0.00016318206,"threshold_uncertainty_score":0.9999539},"labels":[],"label_agreement":null},{"id":"W2785033403","doi":"10.1371/journal.pone.0191709","title":"Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Broad Institute","keywords":"CRISPR; Genome editing; Biology; HEK 293 cells; Transfection; Genetics; Gene; Cas9; DNA; Mutation; Guide RNA; Allele; Computational biology","score_opus":0.01012542987184363,"score_gpt":0.24766084317229006,"score_spread":0.23753541330044642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785033403","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895583,0.000031999476,0.00820226,0.0016970304,0.000039938473,0.00020944829,0.000013834777,0.0000057639686,0.00024142105],"genre_scores_gemma":[0.9951474,0.0000011238099,0.0029935953,0.00024050544,0.0011156407,0.000019923773,0.000012842025,0.000012868069,0.00045610312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994989,0.000014518624,0.000093237046,0.00014734922,0.00012431329,0.00012166895],"domain_scores_gemma":[0.9995372,0.0000033399651,0.000026516016,0.0002856135,0.00010850323,0.00003880961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000073722746,0.0000662245,0.000067687804,0.00001845352,0.00010562826,0.000010653318,0.0001563876,0.000027808843,0.000012760595],"category_scores_gemma":[0.000050749226,0.000042137002,0.000024812953,0.00010931641,0.00004702058,9.814923e-7,0.0001019404,0.00004451872,0.000009278288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010531415,0.00005618555,0.00024972387,0.0000068615177,0.000049236438,1.6256325e-7,0.00019374197,0.00053648994,0.9977219,0.000011177025,0.0010608297,0.00010315863],"study_design_scores_gemma":[0.00014018016,0.00021545944,0.0030664562,0.000020622136,0.000044966484,0.0000017458857,0.000096994925,0.000047313788,0.9955721,0.0000045158317,0.00072746066,0.00006218036],"about_ca_topic_score_codex":0.00000836406,"about_ca_topic_score_gemma":0.00004814311,"teacher_disagreement_score":0.0055890945,"about_ca_system_score_codex":0.0000045374923,"about_ca_system_score_gemma":0.00001635938,"threshold_uncertainty_score":0.1718297},"labels":[],"label_agreement":null},{"id":"W2786398328","doi":"10.1242/dev.160333","title":"Genome and epigenome engineering CRISPR toolkit for <i>in vivo</i> modulation of <i>cis</i> -regulatory interactions and gene expression in the chicken embryo","year":2018,"lang":"en","type":"article","venue":"Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council Canada; Lister Institute of Preventive Medicine; Ovarian Cancer Action","keywords":"Biology; Epigenome; Enhancer; CRISPR; Cas9; Genome editing; Chromatin; Computational biology; Genetics; Genome engineering; Regulation of gene expression; Morpholino; Gene; Genome; Epigenetics; Cell biology; Gene expression; DNA methylation; Gene knockdown","score_opus":0.007257499084222797,"score_gpt":0.25585422021366994,"score_spread":0.24859672112944714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2786398328","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9612705,0.0004979781,0.037883323,0.00002724827,0.00006430022,0.00020649785,0.000005210767,0.0000030711408,0.00004184006],"genre_scores_gemma":[0.98965555,0.00006000842,0.010067307,0.000034623605,0.00006716863,0.00004809836,0.000019503726,0.000009839529,0.00003787982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994735,0.000009023302,0.0001797542,0.0001654572,0.000052808464,0.0001194302],"domain_scores_gemma":[0.9998005,0.000013374915,0.000027697819,0.0001121433,0.000023443416,0.000022833676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017493866,0.0000855658,0.00008416856,0.000057932528,0.00003315036,0.000009003143,0.000058976297,0.000043317115,0.0000024448113],"category_scores_gemma":[0.000014828091,0.000074983574,0.000013636545,0.000048888316,0.000019120123,0.000004657825,0.000049491537,0.00003469521,1.889196e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018131417,0.000013941233,0.0010418566,0.000028004055,0.000006597064,2.429183e-7,0.0008452945,0.00067496765,0.9965913,0.0000076144865,0.000017334103,0.0007546778],"study_design_scores_gemma":[0.0003216736,0.000045699682,0.21249092,0.000024712388,0.0000029871755,0.0000048408165,0.00009411346,0.00050118245,0.7751324,0.000010372145,0.011262428,0.00010869078],"about_ca_topic_score_codex":0.0000033567494,"about_ca_topic_score_gemma":0.000038230195,"teacher_disagreement_score":0.22145896,"about_ca_system_score_codex":0.000011744713,"about_ca_system_score_gemma":0.000019100804,"threshold_uncertainty_score":0.30577415},"labels":[],"label_agreement":null},{"id":"W2787171996","doi":"10.1021/cen-09604-buscon8","title":"Croda buys marine biology services firm","year":2018,"lang":"en","type":"article","venue":"C&EN Global Enterprise","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Business","score_opus":0.002818985191691877,"score_gpt":0.2908211545516341,"score_spread":0.2880021693599422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2787171996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9736509,0.0007821559,0.009082087,0.00011069584,0.00069592317,0.00011165676,0.000059205042,0.000042058957,0.015465365],"genre_scores_gemma":[0.9970159,0.00012140229,0.0011722929,0.00042576654,0.000696941,0.000008460119,0.00012553527,0.000013756514,0.00041992805],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991465,0.000023582612,0.0001546539,0.00033215212,0.00005795841,0.00028512598],"domain_scores_gemma":[0.99944144,0.0000042244374,0.000033360568,0.0003601385,0.000060304243,0.00010055591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006855763,0.00016249128,0.00012182725,0.000017723776,0.000049990536,0.000021303125,0.0002809817,0.0001437387,0.0001391551],"category_scores_gemma":[0.000020018046,0.00015551459,0.00007341255,0.00007895891,0.000074235344,0.0000024567034,0.00036818365,0.000047385034,0.00011136034],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005538902,0.0003086764,0.32184783,0.00019619624,0.00040721148,0.000035221885,0.00033042303,0.00017422307,0.59025395,0.00080386875,0.016575428,0.06851308],"study_design_scores_gemma":[0.0017464971,0.0012273057,0.07543493,0.000052575233,0.00006693069,0.00014550965,0.0001332928,0.0009202753,0.1543085,0.00093842816,0.7642138,0.00081192213],"about_ca_topic_score_codex":0.000121237426,"about_ca_topic_score_gemma":0.00019498124,"teacher_disagreement_score":0.7476384,"about_ca_system_score_codex":0.000019171408,"about_ca_system_score_gemma":0.00002125426,"threshold_uncertainty_score":0.63417006},"labels":[],"label_agreement":null},{"id":"W2788012813","doi":"10.1101/262808","title":"Highly efficient CRISPR gene editing in yeast enabled by double selection","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Multiplex; Cas9; Selection (genetic algorithm); Computational biology; Mutagenesis; Biology; Genetics; Functional genomics; Mutation; Genomics; Gene; Genome; Computer science; Artificial intelligence","score_opus":0.006392318911320983,"score_gpt":0.23611670985710495,"score_spread":0.22972439094578398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788012813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98079485,0.0016836328,0.015226552,0.00005159594,0.0014604477,0.0005230911,0.000118202406,0.000117344345,0.00002429621],"genre_scores_gemma":[0.995231,0.00014428592,0.0025171686,0.00006948991,0.0017173517,0.0001639931,0.0000048241423,0.00013231904,0.000019566884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99744076,0.00006117815,0.00048584098,0.0010857611,0.0002679746,0.0006585151],"domain_scores_gemma":[0.998537,0.000007080085,0.00020653293,0.0007499152,0.00030257137,0.00019691134],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048283464,0.0005036295,0.00038028735,0.00019194595,0.00010886084,0.000121829136,0.00039602842,0.00066683907,0.000022031694],"category_scores_gemma":[0.000079378086,0.00059384096,0.00012711286,0.00032570012,0.00006849148,0.000005092135,0.0004422946,0.00046111332,0.000029830668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051213574,0.00010337474,0.0017879921,0.00013233007,0.00006623181,0.000008412324,0.000006213921,0.0036096436,0.99193615,0.000010170581,0.0022871206,0.0000011415518],"study_design_scores_gemma":[0.0008565691,0.00008095626,0.005587968,0.00012055111,0.00004058442,6.552411e-8,0.000002581685,0.001767489,0.9817591,2.287803e-7,0.009177475,0.0006064522],"about_ca_topic_score_codex":0.00009128714,"about_ca_topic_score_gemma":0.000011002852,"teacher_disagreement_score":0.014436164,"about_ca_system_score_codex":0.00014886186,"about_ca_system_score_gemma":0.00024989957,"threshold_uncertainty_score":0.9996513},"labels":[],"label_agreement":null},{"id":"W2788529035","doi":"10.1534/genetics.117.300124","title":"How Surrogate and Chemical Genetics in Model Organisms Can Suggest Therapies for Human Genetic Diseases","year":2018,"lang":"en","type":"review","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Genome Canada","keywords":"Biology; Model organism; Disease; Genetics; Zebrafish; Organism; Computational biology; Genome; Gene; Medicine","score_opus":0.024530881545478306,"score_gpt":0.3317102033344831,"score_spread":0.30717932178900476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788529035","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016828135,0.97677463,0.0046826187,0.000032097567,0.00014013972,0.0009978622,0.0005110688,0.000023970362,0.000009503593],"genre_scores_gemma":[0.011116142,0.9778375,0.008796649,0.000039680144,0.00071414607,0.0002192165,0.0007668468,0.0002196197,0.0002902141],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976205,0.000057780417,0.00052127277,0.00093259994,0.00017888614,0.0006889195],"domain_scores_gemma":[0.9986712,0.00003211635,0.00017271354,0.0007627618,0.00011134312,0.00024986378],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011357493,0.00070203183,0.00095454446,0.00013595825,0.00009616862,0.00013460523,0.00047932647,0.00062283344,0.000003154835],"category_scores_gemma":[0.000052059007,0.0006836284,0.00029040317,0.00013984091,0.0002257192,0.0000019157426,0.0003099614,0.00017534017,0.0000013343804],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054740805,0.0004612232,0.0009935845,0.025913509,0.0012763197,0.000031944073,0.00058474793,0.0014998976,0.07401171,0.00013096571,0.0036680968,0.8913733],"study_design_scores_gemma":[0.001345221,0.0006086909,0.00013123096,0.001203554,0.001252899,0.000085477026,0.00007230157,0.0014552858,0.014737426,0.00059492607,0.9762964,0.0022165335],"about_ca_topic_score_codex":0.0000034884854,"about_ca_topic_score_gemma":0.00014949599,"teacher_disagreement_score":0.97262836,"about_ca_system_score_codex":0.00004383265,"about_ca_system_score_gemma":0.00024246161,"threshold_uncertainty_score":0.9995615},"labels":[],"label_agreement":null},{"id":"W2788789448","doi":"10.1089/crispr.2017.0009","title":"Allele-Specific CRISPR-Cas9 Genome Editing of the Single-Base P23H Mutation for Rhodopsin-Associated Dominant Retinitis Pigmentosa","year":2018,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Eye Institute; Charles A. King Trust; Research to Prevent Blindness","keywords":"Retinitis pigmentosa; Allele; Biology; Genetics; CRISPR; Cas9; Mutant; Genome editing; Rhodopsin; Gene; Retinal","score_opus":0.020868455491166567,"score_gpt":0.2924181890584948,"score_spread":0.27154973356732826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788789448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8863015,0.0017539539,0.108746506,0.0011722507,0.0011733243,0.0003877565,0.00005739737,0.000010386295,0.00039691833],"genre_scores_gemma":[0.9961716,0.00018503399,0.0011485616,0.00015707304,0.0020460384,0.000013191132,0.000031786534,0.000038871156,0.00020783195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985808,0.00013681986,0.00045682298,0.00021440747,0.00023508105,0.00037608252],"domain_scores_gemma":[0.9987699,0.000061923885,0.00035040584,0.00034870204,0.00039043586,0.00007863054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000913147,0.0001840323,0.00018521876,0.00004334598,0.0004665688,0.00006835918,0.00038877802,0.000115992545,0.000052348223],"category_scores_gemma":[0.00036038517,0.00012221764,0.00022145224,0.00012332488,0.00018092307,0.0000068428217,0.00010177422,0.00019953762,0.000003531696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012400508,0.00006550694,0.000105246545,0.000015926267,0.0000928845,0.000003570238,0.0006167269,0.0002722981,0.98999304,0.000036094327,0.006207792,0.0024669014],"study_design_scores_gemma":[0.0012460835,0.00061307894,0.0024027585,0.000062834,0.000088778965,0.00023234858,0.00088977406,0.00028581586,0.9638354,0.0002648565,0.029875785,0.00020247784],"about_ca_topic_score_codex":0.0000060172583,"about_ca_topic_score_gemma":0.00002526368,"teacher_disagreement_score":0.109870106,"about_ca_system_score_codex":0.000045534896,"about_ca_system_score_gemma":0.000059152877,"threshold_uncertainty_score":0.49838907},"labels":[],"label_agreement":null},{"id":"W2789086709","doi":"10.1007/s00425-018-2866-1","title":"Gene editing by CRISPR/Cas9 in the obligatory outcrossing Medicago sativa","year":2018,"lang":"en","type":"article","venue":"Planta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Genome; Genome editing; Cas9; Biology; Genetics; Gene; Computational biology","score_opus":0.008721587812692102,"score_gpt":0.29820106670574964,"score_spread":0.28947947889305753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789086709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910347,0.0012547768,0.0043768757,0.00039089183,0.00037543027,0.0000958296,0.000038791975,0.00001368247,0.002419036],"genre_scores_gemma":[0.9977626,0.00006370418,0.0003129114,0.00060666335,0.0010341948,0.000007950865,0.000092210896,0.000012943079,0.00010679755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926054,0.00003153315,0.00014884376,0.00020094705,0.00012650531,0.00023165361],"domain_scores_gemma":[0.99966353,0.000020873797,0.000032355332,0.00022016407,0.00001855439,0.000044501077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026797064,0.00010320643,0.00008375335,0.000023899183,0.00009010689,0.000032645894,0.00020485136,0.000085171116,0.00001763044],"category_scores_gemma":[0.000082623825,0.000080246245,0.00002912473,0.00006266764,0.00008427476,0.0000021949675,0.000057176814,0.00009641415,0.000014100352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014754021,0.000023125034,0.005439581,0.000013701489,0.000016321796,0.00000979106,0.0006997589,0.000009525614,0.93129027,0.000012262906,0.05952172,0.0029491642],"study_design_scores_gemma":[0.00033095188,0.000079755206,0.0035372982,0.000022615435,0.000008885195,0.00006294277,0.00047434686,0.00014723506,0.8302211,0.000019801175,0.16493687,0.00015816928],"about_ca_topic_score_codex":0.00004062795,"about_ca_topic_score_gemma":0.000086334905,"teacher_disagreement_score":0.10541516,"about_ca_system_score_codex":0.00000673978,"about_ca_system_score_gemma":0.00002360633,"threshold_uncertainty_score":0.32723472},"labels":[],"label_agreement":null},{"id":"W2789485290","doi":"10.1016/bs.mie.2017.11.030","title":"Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities","year":2018,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Active site; Computational biology; Exonuclease; Proofreading; DNA; Nuclease; Biology; Biochemistry; Enzyme; Chemistry; Cell biology; Polymerase","score_opus":0.024322250853868087,"score_gpt":0.38754946206043844,"score_spread":0.36322721120657037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789485290","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6019901,0.0005301948,0.39585808,0.00010257134,0.0006883712,0.00047129713,0.0000106902935,0.0000409868,0.00030770423],"genre_scores_gemma":[0.47992012,0.0000677573,0.5189436,0.000423115,0.00024478746,0.00013714765,0.000014088671,0.00009137817,0.00015799138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99141604,0.004890064,0.00071813614,0.0015776143,0.00018405728,0.0012140807],"domain_scores_gemma":[0.9963158,0.0022986156,0.0002605872,0.00075001334,0.000107005166,0.00026802855],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005059929,0.0007211063,0.0009839924,0.0005969637,0.00018843713,0.00004904023,0.00046446765,0.0008320083,0.000041731655],"category_scores_gemma":[0.002469872,0.00072106963,0.000096660675,0.00055449957,0.0005691585,0.000028444721,0.00047756158,0.0008672487,0.0000047530025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092203246,0.0002725259,0.0029906444,0.000059092818,0.00006443461,0.000073223906,0.00070102804,0.0010662581,0.96223646,0.00001880809,0.000639631,0.030955842],"study_design_scores_gemma":[0.0015510325,0.0031057976,0.0091336565,0.00006892036,0.000041310635,0.00016609364,0.000702817,0.0002883368,0.9805352,0.0002471351,0.0033080187,0.0008516888],"about_ca_topic_score_codex":0.0001783951,"about_ca_topic_score_gemma":0.0002796925,"teacher_disagreement_score":0.12308553,"about_ca_system_score_codex":0.000107398315,"about_ca_system_score_gemma":0.00011790236,"threshold_uncertainty_score":0.99952406},"labels":[],"label_agreement":null},{"id":"W2790354793","doi":"10.1007/s00216-018-1010-1","title":"Critical assessment of digital PCR for the detection and quantification of genetically modified organisms","year":2018,"lang":"en","type":"review","venue":"Analytical and Bioanalytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"FP7 Food, Agriculture and Fisheries, Biotechnology; Javna Agencija za Raziskovalno Dejavnost RS; Shanghai Jiao Tong University; European Commission","keywords":"Digital polymerase chain reaction; Chromatography; Computational biology; Environmental chemistry; Chemistry; Biochemical engineering; Polymerase chain reaction; Biology; Engineering; Genetics; Gene","score_opus":0.03178715787191659,"score_gpt":0.37023134630306276,"score_spread":0.33844418843114615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790354793","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00055035175,0.80137044,0.19689265,0.000101559395,0.000058642392,0.00039824436,0.00021619009,0.000009225715,0.00040272748],"genre_scores_gemma":[0.3400227,0.6587397,0.0005979341,0.000008762029,0.00029123356,0.000028550936,0.00010458869,0.00003546539,0.00017106913],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984538,0.000018407354,0.0006284034,0.0004906147,0.00018062067,0.00022813924],"domain_scores_gemma":[0.9987961,0.00034720352,0.0001221788,0.00037813484,0.0002113357,0.00014507018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023462235,0.00028232398,0.00069356797,0.0000312261,0.000059474565,0.00005095217,0.00018935234,0.0004116656,0.000012673281],"category_scores_gemma":[0.0006062448,0.00019085935,0.00030452013,0.00013331824,0.0007937271,0.00000382837,0.00015572012,0.00015388416,4.2402277e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017134316,0.00064348726,0.00010202774,0.04970218,0.002909892,0.0000038117487,0.00001731846,0.000024410445,0.06778704,0.005179978,0.00025496568,0.8732036],"study_design_scores_gemma":[0.0022490276,0.0027637396,0.00048536743,0.004106357,0.021336773,0.0004119279,0.0002264219,0.13900211,0.15423563,0.0021308446,0.66968805,0.003363756],"about_ca_topic_score_codex":0.0000017605826,"about_ca_topic_score_gemma":8.767077e-7,"teacher_disagreement_score":0.8698398,"about_ca_system_score_codex":0.000010462139,"about_ca_system_score_gemma":0.000097419215,"threshold_uncertainty_score":0.77830184},"labels":[],"label_agreement":null},{"id":"W2790739701","doi":"10.1101/252163","title":"Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Danmarks Frie Forskningsfond; Deutsche Forschungsgemeinschaft; Children's Health Research Institute; Sundhed og Sygdom, Det Frie Forskningsråd; Amon G. Carter Foundation","keywords":"Genome editing; Induced pluripotent stem cell; Cas9; CRISPR; Biology; Computational biology; Homologous recombination; Genome; Genetics; Gene; Embryonic stem cell","score_opus":0.008075649312681515,"score_gpt":0.23054064611422698,"score_spread":0.22246499680154547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790739701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889204,0.001997695,0.007434556,0.000019721283,0.0008656447,0.0004144991,0.0002806855,0.00006124847,0.000005545463],"genre_scores_gemma":[0.99325335,0.0002687396,0.005594582,0.000022696919,0.00070172583,0.00003886948,0.000003868396,0.0001048529,0.000011330231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979073,0.00008334972,0.00053528784,0.0008496241,0.00021610504,0.00040836557],"domain_scores_gemma":[0.9981974,0.000011398168,0.00041207438,0.0007707227,0.0004556559,0.00015278772],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038170093,0.0004335342,0.0004137203,0.0001607334,0.00017636587,0.00007203603,0.00037444962,0.00059600844,0.000013867108],"category_scores_gemma":[0.000044376397,0.00052245177,0.00009995606,0.00017586985,0.00012972247,0.000009395606,0.00048753634,0.00032167966,0.0000017652119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000063292314,0.00005850028,0.001349037,0.0002884928,0.00012639894,0.0000044093185,0.0000079119845,0.00024738497,0.99771225,0.000025378611,0.00017170196,0.0000022102495],"study_design_scores_gemma":[0.00043208958,0.00019343886,0.0054454682,0.00012280358,0.00010428792,1.6981802e-7,0.0000045677516,0.00029347974,0.99262637,0.0000049643945,0.0002620188,0.00051032903],"about_ca_topic_score_codex":0.00020996369,"about_ca_topic_score_gemma":0.000008985901,"teacher_disagreement_score":0.0050858627,"about_ca_system_score_codex":0.000116898176,"about_ca_system_score_gemma":0.0001544099,"threshold_uncertainty_score":0.9997227},"labels":[],"label_agreement":null},{"id":"W2790778573","doi":"10.1534/g3.117.300327","title":"Inducible Genome Editing with Conditional CRISPR/Cas9 Mice","year":2018,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal","funders":"McGill University; Lymphoma Research Foundation","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Biology; Genetics; Computer science; Gene","score_opus":0.009883502025762634,"score_gpt":0.2817411919817457,"score_spread":0.27185768995598303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790778573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6531086,0.21494266,0.12465046,0.00026969737,0.0009843349,0.00064576685,0.0002146595,0.00011047238,0.00507331],"genre_scores_gemma":[0.9696722,0.010633035,0.0135069415,0.00046578175,0.004273987,0.000046719222,0.00046294174,0.00010487991,0.00083351776],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980396,0.000037720925,0.00032790605,0.0006850988,0.00028877796,0.00062088866],"domain_scores_gemma":[0.99873024,0.000012414189,0.000112723996,0.0006230467,0.00030644206,0.00021513541],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001725662,0.00036021322,0.00023249745,0.0001246716,0.00024155706,0.00006751106,0.0003804977,0.00021116185,0.00012865938],"category_scores_gemma":[0.0000067062947,0.00035515978,0.0000952045,0.00024193966,0.00024910356,0.0000056901877,0.00021450284,0.00012743138,0.00010520165],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066365305,0.000066164284,0.004457405,0.000050121653,0.00020803226,0.00001249861,0.00024109674,0.0049344106,0.9121333,0.0000629059,0.000966324,0.07680143],"study_design_scores_gemma":[0.0005686435,0.00068010873,0.002465475,0.000009612118,0.00005411717,0.00012682135,0.00021098476,0.0002771411,0.4616524,0.00007430033,0.53339446,0.00048592736],"about_ca_topic_score_codex":0.000009366983,"about_ca_topic_score_gemma":0.00007933844,"teacher_disagreement_score":0.53242815,"about_ca_system_score_codex":0.000027316712,"about_ca_system_score_gemma":0.00014258057,"threshold_uncertainty_score":0.99989},"labels":[],"label_agreement":null},{"id":"W2791633339","doi":"10.1787/38a54acb-en","title":"Gene editing in an international context","year":2018,"lang":"en","type":"paratext","venue":"OECD science, technology and industry working papers","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Massachusetts Institute of Technology","keywords":"Genome editing; Context (archaeology); Sustainability; Corporate governance; Political science; Engineering ethics; Biology; Engineering; Business; Genome; Gene; Ecology; Genetics","score_opus":0.011751411376208163,"score_gpt":0.3043378726449084,"score_spread":0.29258646126870025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791633339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8851693,0.00122534,0.00006158738,0.00035354035,0.0036832413,0.00016571043,0.000017684417,0.000035642304,0.10928793],"genre_scores_gemma":[0.9886283,0.00030183993,0.00047018428,0.00018738235,0.0011738583,0.00002375548,0.00008128252,0.00002472331,0.009108648],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99828553,0.000016009864,0.00025031276,0.0007905378,0.00018135953,0.00047621896],"domain_scores_gemma":[0.99932146,0.000006127919,0.000106879656,0.00040873318,0.000057625562,0.00009916974],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00034867987,0.0002552658,0.00021126866,0.00089594687,0.00022140531,0.00008316266,0.00079368375,0.0016152662,0.00023974452],"category_scores_gemma":[0.00007315673,0.00026599062,0.000033502878,0.00056148635,0.0012274679,0.00000956054,0.00037812436,0.00091042113,0.00005007465],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042108382,0.00008101767,0.041489962,0.00002259469,0.00007260378,0.000023426841,0.00015420814,0.0004227668,0.81414723,0.00047741228,0.009871152,0.13319552],"study_design_scores_gemma":[0.00044001,0.00023622085,0.0012065596,0.00016338278,0.000011369631,0.00008076499,0.0007020897,0.00011757535,0.21091999,0.000027053264,0.7855892,0.0005057755],"about_ca_topic_score_codex":0.000004793047,"about_ca_topic_score_gemma":0.00003152833,"teacher_disagreement_score":0.77571803,"about_ca_system_score_codex":0.00004103959,"about_ca_system_score_gemma":0.0001745847,"threshold_uncertainty_score":0.99997926},"labels":[],"label_agreement":null},{"id":"W2791875139","doi":"10.1016/j.omtn.2018.03.007","title":"CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer’s Disease","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Common Fund; Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; National Institutes of Health; Marcus och Amalia Wallenbergs minnesfond; Hjärnfonden; National Center for Research Resources; National Institute of General Medical Sciences; Kosciuszko Foundation","keywords":"CRISPR; Amyloid precursor protein; Biology; Mutant; Allele; Cas9; Point mutation; Gene; Transgene; Genetics; Molecular biology; Alzheimer's disease; Disease; Medicine; Pathology","score_opus":0.014089067671773682,"score_gpt":0.2980079156000912,"score_spread":0.2839188479283175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791875139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8944419,0.0046666567,0.09917407,0.00022473263,0.00017984862,0.0008780003,0.0000691081,0.000037431066,0.0003282312],"genre_scores_gemma":[0.9970347,0.0002124435,0.0012224226,0.0007935963,0.00020002718,0.0001386378,0.00019818764,0.00008297573,0.00011696632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985779,0.000089696565,0.00027105052,0.00045087503,0.00025142982,0.00035902584],"domain_scores_gemma":[0.99882007,0.00001352619,0.00010338359,0.0007801724,0.00014446028,0.00013840587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019311305,0.00027624497,0.00020744532,0.00004388852,0.00013461114,0.000030695268,0.00046563902,0.0001507102,0.000035751906],"category_scores_gemma":[0.00005238909,0.00021588682,0.00030032423,0.0001695763,0.00023875703,0.0000057644397,0.00010243198,0.00009877642,0.000008526314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008775669,0.00027547876,0.004171574,0.000034148947,0.00057057926,0.0000026356843,0.0003642859,0.00023410562,0.985289,0.00015119325,0.00083209085,0.007197383],"study_design_scores_gemma":[0.0024510243,0.001114256,0.028313586,0.000019688818,0.00021858065,0.000018131048,0.00013431776,0.0026264384,0.9288619,0.0005380959,0.035095077,0.0006088757],"about_ca_topic_score_codex":0.000017995057,"about_ca_topic_score_gemma":0.000002697182,"teacher_disagreement_score":0.10259282,"about_ca_system_score_codex":0.000010209492,"about_ca_system_score_gemma":0.00006910752,"threshold_uncertainty_score":0.8803609},"labels":[],"label_agreement":null},{"id":"W2791921126","doi":"10.1073/pnas.1720962115","title":"Double-stranded DNA break polarity skews repair pathway choice during intrachromosomal and interchromosomal recombination","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Government of Canada","keywords":"Recombination; Polarity (international relations); Genetics; Biology; DNA; DNA repair; Cell biology; Gene; Cell","score_opus":0.020203392299149702,"score_gpt":0.31374592362600723,"score_spread":0.29354253132685754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791921126","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99802345,0.00009255185,0.0000051969664,0.0003457544,0.000029928406,0.00011164867,0.00000767959,0.000010161806,0.0013736134],"genre_scores_gemma":[0.99885267,0.000020086147,0.00080125895,0.000033464068,0.00020090552,0.0000047001063,4.916475e-7,0.000004374342,0.00008207018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990913,0.000004613964,0.00021246476,0.0002466684,0.00031783961,0.00012710583],"domain_scores_gemma":[0.9996214,0.0000140944285,0.00013743994,0.000011597689,0.00018238254,0.00003307722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046524708,0.000086525346,0.00009254042,0.000060993883,0.00015241331,0.000017730166,0.00028680326,0.00010015902,0.0000054816865],"category_scores_gemma":[0.0001768399,0.00006744684,0.00005550486,0.00019283585,0.0004922303,0.000028158782,0.00015263949,0.000090319634,2.9147316e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000310441,0.000024134546,0.008304931,0.000049259652,0.000013499758,3.0287854e-9,0.000079775615,0.0000049406885,0.99027264,0.0009616825,0.000045117635,0.0002129949],"study_design_scores_gemma":[0.00034002936,0.00010359658,0.17287366,0.000036346315,0.0000056442022,0.000018654033,0.00003378172,0.00022117487,0.82534325,0.0007884287,0.00016781295,0.00006764548],"about_ca_topic_score_codex":0.000007922136,"about_ca_topic_score_gemma":0.0000011439239,"teacher_disagreement_score":0.16492939,"about_ca_system_score_codex":0.00001153049,"about_ca_system_score_gemma":0.000020039088,"threshold_uncertainty_score":0.27504024},"labels":[],"label_agreement":null},{"id":"W2792416096","doi":"10.1373/clinchem.2017.278317","title":"Counterpoint: The Potential Harms of Human Gene Editing Using CRISPR-Cas9","year":2018,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Counterpoint; CRISPR; Genome editing; Computational biology; Biology; Gene; Computer science; Genetics; Psychology","score_opus":0.027290814619336294,"score_gpt":0.4019187278158515,"score_spread":0.37462791319651517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792416096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98914844,0.00030225443,0.009153361,0.000069933354,0.00038710708,0.000060898084,0.000015007801,0.000011250361,0.00085172954],"genre_scores_gemma":[0.994541,0.000030160762,0.00068117346,0.00012786675,0.0043759067,0.0000027171836,0.000033125154,0.000022771264,0.00018526959],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886674,0.000023643439,0.000466242,0.0003013117,0.00012549809,0.00021654795],"domain_scores_gemma":[0.9991726,0.00001969557,0.00013775966,0.0004545098,0.00013633775,0.000079097066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003803908,0.00013504465,0.00017405732,0.0000063664365,0.00011042692,0.000017086604,0.0002907069,0.00019969248,0.000118832075],"category_scores_gemma":[0.00018813956,0.00011072451,0.00017999904,0.000048498594,0.00036985948,0.0000019262425,0.00019099009,0.0001682669,0.000004463636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019849762,0.000040048257,0.0017687096,0.000030446836,0.000046147405,0.000002965642,0.00001270216,0.00005226209,0.99628633,0.0000019033571,0.0014524048,0.00028623405],"study_design_scores_gemma":[0.00037082663,0.000095990705,0.0007574268,0.00002310485,0.000043248903,0.000038749477,0.00009929549,0.0011971416,0.99485624,0.00003107018,0.0023542906,0.00013261533],"about_ca_topic_score_codex":0.0000062541044,"about_ca_topic_score_gemma":0.0000010969142,"teacher_disagreement_score":0.008472188,"about_ca_system_score_codex":0.0000065906693,"about_ca_system_score_gemma":0.000038612892,"threshold_uncertainty_score":0.45152146},"labels":[],"label_agreement":null},{"id":"W2793161357","doi":"10.1016/j.ymeth.2018.02.023","title":"Catch the live show: Visualizing damaged DNA in vivo","year":2018,"lang":"en","type":"review","venue":"Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"DNA; DNA repair; Computational biology; DNA damage; Biology; Genome; Cell biology; Genetics; Gene","score_opus":0.05731361266106838,"score_gpt":0.4819024155868326,"score_spread":0.42458880292576423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793161357","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006472997,0.9684009,0.029738268,0.000010596016,0.00041622747,0.00034722456,0.000012177024,0.000011754983,0.0009981416],"genre_scores_gemma":[0.000012740944,0.9705193,0.027294561,0.00005085133,0.0006436237,0.00009256871,0.000038840375,0.00006417667,0.0012833442],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980478,0.0007521425,0.0003678796,0.00044464128,0.000087100634,0.00030039143],"domain_scores_gemma":[0.9990152,0.0001290133,0.00010354808,0.00066578534,0.00003257665,0.00005387719],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015561535,0.0003186982,0.0006132118,0.00006927678,0.00006016181,0.000032233704,0.00044996414,0.00035932419,0.000055657798],"category_scores_gemma":[0.00028035723,0.00022279551,0.00029001178,0.00018618193,0.000067320725,0.0000010606282,0.0002530433,0.00026656518,0.000015685737],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004318825,0.000025459804,0.0000063570797,0.002377104,0.0001479195,0.0000059902704,0.00026452323,0.000006835767,0.006158236,0.000017247845,0.0035817293,0.9874043],"study_design_scores_gemma":[0.000068230554,0.000049214308,0.000003900591,0.0007302456,0.000127793,0.0000210726,0.000051169813,0.000016543872,0.007500303,0.000011337785,0.99115044,0.0002697566],"about_ca_topic_score_codex":0.000027158601,"about_ca_topic_score_gemma":0.000044461085,"teacher_disagreement_score":0.9875687,"about_ca_system_score_codex":0.000026861862,"about_ca_system_score_gemma":0.000103328544,"threshold_uncertainty_score":0.90853375},"labels":[],"label_agreement":null},{"id":"W2793258504","doi":"10.1016/j.plantsci.2018.03.023","title":"A Golden Gate and Gateway double-compatible vector system for high throughput functional analysis of genes","year":2018,"lang":"en","type":"article","venue":"Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Biology; CRISPR; Computational biology; Gene; Cloning (programming); Genetics; Cas9; Genome; Vector (molecular biology); Genome editing; Computer science","score_opus":0.016303148593157547,"score_gpt":0.2790864763437014,"score_spread":0.2627833277505438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793258504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9704057,0.00034326717,0.028700782,0.000013164316,0.00020723046,0.00009338735,0.000105569634,0.0000077386685,0.00012316345],"genre_scores_gemma":[0.9983775,0.000021126263,0.0013765615,0.000008982584,0.00009861155,0.0000108712875,0.000048133574,0.0000037442637,0.000054486238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935997,0.0000041057656,0.0001136967,0.00025365737,0.00011738154,0.00015116653],"domain_scores_gemma":[0.99965054,0.000011946758,0.00003974619,0.0001536285,0.00009689961,0.000047231377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018889215,0.00006828603,0.00011783849,0.00008991487,0.000092634844,0.000019284156,0.000113249705,0.000029404564,0.000005172653],"category_scores_gemma":[0.000011165208,0.00005786895,0.00003385093,0.000290978,0.00016912568,0.0000041469625,0.00005239764,0.000012990167,0.0000010178206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065813474,0.000008623258,0.0039142636,0.00003193598,0.00007268193,2.2298283e-7,0.000050735816,0.001125847,0.99384993,0.00062961545,0.00006751249,0.00018280366],"study_design_scores_gemma":[0.00032052753,0.0001435456,0.03377631,0.000011333549,0.00010996284,0.000008168032,0.000050747825,0.012459765,0.9521918,0.000006228127,0.00082326523,0.000098309385],"about_ca_topic_score_codex":0.00007074914,"about_ca_topic_score_gemma":0.0000742045,"teacher_disagreement_score":0.041658107,"about_ca_system_score_codex":0.000007773588,"about_ca_system_score_gemma":0.000039861665,"threshold_uncertainty_score":0.23598273},"labels":[],"label_agreement":null},{"id":"W2793996648","doi":"10.1007/s10806-018-9719-6","title":"Genetically Modifying Livestock for Improved Welfare: A Path Forward","year":2018,"lang":"en","type":"article","venue":"Journal of Agricultural and Environmental Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Welfare; Animal welfare; Status quo; Argument (complex analysis); Agriculture; Livestock; Genetically modified organism; Public economics; Biotechnology; Economics; Business; Biology; Gene; Genetics; Market economy","score_opus":0.010140550027281345,"score_gpt":0.2625637185753724,"score_spread":0.25242316854809105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793996648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848093,0.001000396,0.012699976,0.0011701377,0.00015624016,0.00011134353,0.000018319288,0.0000023093892,0.000031974258],"genre_scores_gemma":[0.99053586,0.00082196086,0.0077363695,0.00018199651,0.0005749964,0.0000032554897,0.00002369304,0.000008697752,0.00011319261],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994129,0.000015540609,0.00020122052,0.00012470837,0.000096510375,0.00014912311],"domain_scores_gemma":[0.9996928,0.000015924377,0.00008802327,0.000063259315,0.0000354492,0.00010455653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016091159,0.00011310435,0.00011538778,0.000012699497,0.00012684581,0.000020267044,0.0000847971,0.0001576213,0.000005079537],"category_scores_gemma":[0.00004740311,0.000073717245,0.00009537783,0.00001731049,0.00009847275,0.000005630356,0.000061406136,0.00017428852,7.5804996e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006187544,0.0000294744,0.00015160882,0.000019784593,0.000049023627,3.9821776e-7,0.00022328498,0.00013012368,0.99634176,0.000027043709,0.00027519724,0.0026904275],"study_design_scores_gemma":[0.0037402427,0.010059983,0.2704833,0.00010581813,0.000287491,0.0010549702,0.00356731,0.0010112149,0.6203349,0.00036549644,0.08799705,0.0009922097],"about_ca_topic_score_codex":0.0000013735804,"about_ca_topic_score_gemma":0.0000033980334,"teacher_disagreement_score":0.37600684,"about_ca_system_score_codex":0.000012250022,"about_ca_system_score_gemma":0.000010450615,"threshold_uncertainty_score":0.30061018},"labels":[],"label_agreement":null},{"id":"W2794019234","doi":"10.1080/20477724.2018.1427192","title":"Population modification of Anopheline species to control malaria transmission","year":2017,"lang":"en","type":"review","venue":"Pathogens and Global Health","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Bill and Melinda Gates Foundation; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Institute of Genetics; University of California; W. M. Keck Foundation","keywords":"Gene drive; Malaria; Population; Biology; Vector (molecular biology); Effector; Transmission (telecommunications); Mosquito control; Computational biology; Biotechnology; CRISPR; Gene; Computer science; Genetics; Medicine; Environmental health; Immunology","score_opus":0.042756850748662915,"score_gpt":0.42006820691395996,"score_spread":0.37731135616529704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794019234","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015022595,0.96601903,0.032243807,0.000085075495,0.000113613874,0.0005366317,0.000755552,0.0000058005826,0.00009027264],"genre_scores_gemma":[0.011463736,0.98630047,0.0013370398,0.0000376699,0.00017564069,0.000016595204,0.0005843646,0.000014783703,0.0000696976],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989667,0.000055522753,0.00039661597,0.00030644386,0.00009289386,0.00018181147],"domain_scores_gemma":[0.99925923,0.000004707254,0.00021026345,0.00032772694,0.0000437402,0.0001543209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022220185,0.00019381782,0.00066088606,0.000031914315,0.000081618105,0.000014739979,0.00011199228,0.00017772056,0.00000342871],"category_scores_gemma":[0.00002676271,0.00016685738,0.00013651888,0.00004938906,0.000015491889,0.0000013683433,0.00002890564,0.00004906296,0.0000015717195],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001289892,0.000016728643,0.000036093665,0.002760043,0.000023248635,4.3961012e-7,0.000005983221,0.000037016063,0.00031599967,0.00015869731,0.000109888526,0.99652296],"study_design_scores_gemma":[0.00020876862,0.00022373341,0.0032191242,0.0011837806,0.00009498506,0.000017548185,0.0000033562942,0.00006226796,0.00002341225,0.000021099204,0.99475545,0.0001864859],"about_ca_topic_score_codex":0.00006197228,"about_ca_topic_score_gemma":0.000024628958,"teacher_disagreement_score":0.99633646,"about_ca_system_score_codex":0.000030633284,"about_ca_system_score_gemma":0.00010802995,"threshold_uncertainty_score":0.68042463},"labels":[],"label_agreement":null},{"id":"W2794379535","doi":"10.21769/bioprotoc.2765","title":"Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9","year":2018,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Genome editing; CRISPR; Selectable marker; Cas9; Biology; Genetics; Homology directed repair; Homologous recombination; Locus (genetics); Genome; Computational biology; Gene; DNA; DNA repair; Transformation (genetics); Nucleotide excision repair","score_opus":0.02518560121350588,"score_gpt":0.3547524386194919,"score_spread":0.329566837405986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794379535","genre_codex":"protocol","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36819017,0.00005286385,0.10576374,0.000067578156,0.00071733503,0.51801455,0.000038962946,0.000099869896,0.0070549375],"genre_scores_gemma":[0.69151837,8.198092e-7,0.015406231,0.00013347308,0.0037537033,0.2887912,0.000026585634,0.00008806017,0.00028156504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879646,0.00003509168,0.00029584332,0.00038868916,0.00014113156,0.00034278276],"domain_scores_gemma":[0.99940634,0.0000053194926,0.000072538394,0.0003532308,0.000079442914,0.00008314238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020513793,0.00018375489,0.0001381895,0.00008312254,0.00007389927,0.000039930314,0.00019037195,0.00017001454,0.000079996076],"category_scores_gemma":[0.000078580495,0.00018183824,0.00006380118,0.00014881873,0.00006447925,0.000005333874,0.0001699903,0.000085383486,0.00002779997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008145935,0.00005960598,0.0010930917,0.000044456112,0.000007908556,0.0000043216965,0.00004090731,0.00013823688,0.9919377,0.000004079033,0.00033148416,0.0062567787],"study_design_scores_gemma":[0.001179564,0.00043619817,0.0028846024,0.000072549425,0.000005640242,0.000021817164,0.00006624022,0.0018289892,0.7170576,0.000013143384,0.27613953,0.00029412852],"about_ca_topic_score_codex":0.00002824538,"about_ca_topic_score_gemma":0.000058386384,"teacher_disagreement_score":0.32332817,"about_ca_system_score_codex":0.000036960228,"about_ca_system_score_gemma":0.000039563547,"threshold_uncertainty_score":0.7415148},"labels":[],"label_agreement":null},{"id":"W2794836173","doi":"10.1016/j.jim.2018.03.009","title":"Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins","year":2018,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Pew Charitable Trusts; Burroughs Wellcome Fund; University of California, San Francisco; Howard Hughes Medical Institute","keywords":"CRISPR; Cas9; Genome editing; Biology; Ribonucleoprotein; Electroporation; Genome engineering; Computational biology; Oligonucleotide; Guide RNA; Gene; Genetics; Cell biology; RNA","score_opus":0.011526405787848413,"score_gpt":0.33948651227427756,"score_spread":0.32796010648642915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794836173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79705054,0.0015531606,0.20083936,0.000031421816,0.00013931432,0.000083533116,5.900253e-7,0.00000675152,0.00029531246],"genre_scores_gemma":[0.6440106,0.00012361983,0.35548908,0.000049110484,0.00025937567,0.0000034071995,6.785298e-7,0.00001728652,0.00004681757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988904,0.00012216612,0.0004153241,0.0001825371,0.00012111069,0.00026848863],"domain_scores_gemma":[0.9993988,0.000033060685,0.0001435028,0.0002322424,0.00012309717,0.000069240836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057714933,0.00016982526,0.00028440313,0.00011154228,0.000038934017,0.00002032372,0.0002710804,0.00016949285,0.00002761792],"category_scores_gemma":[0.00012323643,0.00012490536,0.00009730705,0.00015015242,0.000096829266,0.0000050992803,0.00009864069,0.00028787245,0.000002325028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010834036,0.00006076419,0.0008469146,0.000014187476,0.000052549043,0.000030243355,0.000031330583,0.0008583771,0.9854431,0.000012403605,0.000039016795,0.012502735],"study_design_scores_gemma":[0.000980075,0.0031978919,0.10466816,0.000060986964,0.000023121362,0.00019589347,0.000027657548,0.000086987806,0.88465565,0.00005244037,0.0058331587,0.00021794367],"about_ca_topic_score_codex":0.000004741227,"about_ca_topic_score_gemma":0.0000023465614,"teacher_disagreement_score":0.15464972,"about_ca_system_score_codex":0.000030542586,"about_ca_system_score_gemma":0.000035314722,"threshold_uncertainty_score":0.5093493},"labels":[],"label_agreement":null},{"id":"W2794949547","doi":"10.3389/fgene.2018.00117","title":"Efficient Gene Transfer and Gene Editing in Sterlet (Acipenser ruthenus)","year":2018,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Beijing Academy of Agricultural and Forestry Sciences; National Natural Science Foundation of China; University of Ottawa","keywords":"Transcription activator-like effector nuclease; CRISPR; Biology; Genome editing; Cas9; Gene; Nuclease; Guide RNA; Mutant; Genetics; Molecular biology; Cell biology","score_opus":0.004960123797178067,"score_gpt":0.24439002595537054,"score_spread":0.2394299021581925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794949547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89777595,0.0038370132,0.096948594,0.00003896828,0.0009957245,0.00017762535,0.00001513522,0.000007726888,0.0002032382],"genre_scores_gemma":[0.9761752,0.00038376686,0.022652041,0.00010793698,0.0005083883,0.000014864826,0.000022163149,0.00003371561,0.00010192266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988281,0.00003583004,0.00026328236,0.00038991676,0.00011462541,0.0003682106],"domain_scores_gemma":[0.999586,0.000004620991,0.00001883198,0.00027224174,0.000036465666,0.00008186071],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019098907,0.00018199444,0.000177677,0.00012016645,0.000038880025,0.000020154941,0.00014464055,0.00016234112,0.0000071656095],"category_scores_gemma":[0.000021016942,0.0001991185,0.00003807222,0.00013283083,0.00011826109,0.0000011940034,0.00007553344,0.00010438618,0.0000024712233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013619398,0.00011666556,0.09483849,0.000057402438,0.00005578009,0.000026878964,0.0016677096,0.016142104,0.86476785,0.000010007051,0.0017856408,0.020395286],"study_design_scores_gemma":[0.0022762457,0.0004462792,0.045990363,0.00005123954,0.000029551207,0.000039622064,0.00055648875,0.03535916,0.8987053,0.00007586719,0.015819805,0.00065007794],"about_ca_topic_score_codex":0.0000083507875,"about_ca_topic_score_gemma":0.00005989966,"teacher_disagreement_score":0.078399226,"about_ca_system_score_codex":0.000019663446,"about_ca_system_score_gemma":0.000024472536,"threshold_uncertainty_score":0.8119817},"labels":[],"label_agreement":null},{"id":"W2795045463","doi":"10.1093/schbul/sby014.159","title":"39.1 DNA METHYLATION OF IMMUNE CELLS IN PERSONS AT CLINICAL HIGH RISK FOR PSYCHOSIS","year":2018,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Psychosis; Schizophrenia (object-oriented programming); DNA methylation; Immune system; Psychology; Anxiety; Prepulse inhibition; Medicine; Internal medicine; Immunology; Psychiatry; Biology; Genetics; Gene; Gene expression","score_opus":0.010472723396479939,"score_gpt":0.30795612036626496,"score_spread":0.29748339696978504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795045463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917237,0.00050677796,0.006571389,0.00024024774,0.00046470226,0.00024550065,0.000101745325,0.000009527408,0.00013640731],"genre_scores_gemma":[0.98267233,0.00019516534,0.016128963,0.00003639844,0.00045291687,0.000029880595,0.00006223348,0.000025602847,0.00039652534],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889827,0.00006763776,0.00042145656,0.00032840887,0.00007982016,0.0002044129],"domain_scores_gemma":[0.99936247,0.000052116524,0.00013050437,0.0003339197,0.00006583927,0.000055154174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005026716,0.00013353793,0.00020780173,0.00005265928,0.00005442424,0.000006292106,0.00014870983,0.00018494748,0.00012780863],"category_scores_gemma":[0.00014371343,0.00013494409,0.00017071754,0.000074683965,0.00009329279,8.672169e-7,0.00007474887,0.00008915017,0.000029133525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014004256,0.00010188673,0.0027040972,0.000031278145,0.000075171076,3.730501e-7,0.00007232578,0.000131355,0.97573006,0.000040957108,0.009747906,0.009964168],"study_design_scores_gemma":[0.0024300267,0.0006721818,0.038269997,0.000022263093,0.0000422651,0.0000013250362,0.000028052664,0.00015592898,0.8786187,0.000073844945,0.07947362,0.00021175828],"about_ca_topic_score_codex":0.000082257255,"about_ca_topic_score_gemma":0.00012211641,"teacher_disagreement_score":0.09711132,"about_ca_system_score_codex":0.00000999177,"about_ca_system_score_gemma":0.000018102026,"threshold_uncertainty_score":0.550286},"labels":[],"label_agreement":null},{"id":"W2795075167","doi":"10.1038/s41579-018-0002-7","title":"CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms","year":2018,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"CRISPR; Biology; Genome editing; Computational biology; Identification (biology); Gene; Genetics; Cas9; Ecology","score_opus":0.030699728166191015,"score_gpt":0.366325403412361,"score_spread":0.33562567524616993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795075167","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000022623954,0.9680015,0.028482229,0.00003122331,0.00070239673,0.0024703247,0.00024848082,0.000009207798,0.00003204947],"genre_scores_gemma":[0.00008375701,0.9885105,0.007928533,0.00023726228,0.000860323,0.00022207473,0.0019482942,0.00008860376,0.000120642544],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977325,0.00019389178,0.0009857017,0.00064635987,0.000040532337,0.00040102183],"domain_scores_gemma":[0.99810153,0.00022597329,0.00055551925,0.0009002215,0.00016449277,0.00005225625],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00067550666,0.00052019104,0.0014346787,0.00007990792,0.000083989944,0.000029571747,0.00072712585,0.0015735398,0.000046328078],"category_scores_gemma":[0.00034243954,0.00033941795,0.0008765182,0.000145823,0.00015376693,0.0000023858715,0.00014417323,0.00046898623,0.000032264743],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027119313,0.000047796326,0.00000117609,0.011135843,0.00031127583,5.225397e-7,0.0000056801236,0.000017367114,0.28880236,0.00005373343,0.018529242,0.6810679],"study_design_scores_gemma":[0.0001915905,0.00019894195,0.0000025696468,0.0010697792,0.0007423683,0.00006461466,0.0000013282365,0.0000062059357,0.016594268,0.0000053855424,0.9807797,0.00034326018],"about_ca_topic_score_codex":0.0000016543632,"about_ca_topic_score_gemma":0.000010861733,"teacher_disagreement_score":0.9622505,"about_ca_system_score_codex":0.000038130944,"about_ca_system_score_gemma":0.00023117197,"threshold_uncertainty_score":0.99990577},"labels":[],"label_agreement":null},{"id":"W2795605127","doi":"10.1016/j.jmb.2018.03.030","title":"Development of the SapI/AarI Incision Mediated Plasmid Editing Method","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; State Key Laboratory of Synthetical Automation for Process Industries; National Institutes of Health; Alberta Agricultural Research Institute; University of Southern California","keywords":"Plasmid; Insert (composites); Mutagenesis; Computational biology; Cloning (programming); Cloning vector; DNA; Biology; Molecular cloning; Restriction enzyme; Restriction site; Restriction digest; Genetics; Recombinant DNA; Computer science; Vector (molecular biology); Gene; Mutation; Complementary DNA; Engineering","score_opus":0.008169451815969085,"score_gpt":0.3486577155780738,"score_spread":0.3404882637621047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795605127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67886126,0.00050016533,0.31977984,0.0001175567,0.0005009179,0.00004897152,0.0000028602337,0.0000019097538,0.00018649061],"genre_scores_gemma":[0.90299904,0.000023364142,0.09642661,0.00017936614,0.0003374739,0.000001149587,0.0000067371875,0.000012989628,0.00001327519],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989885,0.00010711547,0.00046714148,0.00013407785,0.00013114803,0.0001720168],"domain_scores_gemma":[0.9991616,0.000025550646,0.00031339217,0.0001947143,0.0002478291,0.000056935136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006153818,0.00011364688,0.00018739978,0.00006451665,0.000053387932,0.000004475861,0.0003053837,0.00016316093,0.0000148672425],"category_scores_gemma":[0.0003648309,0.000077369805,0.00012350582,0.000106219166,0.000087800945,0.0000016783291,0.00017578942,0.00012831001,0.0000020351263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037506314,0.000019262485,0.00046233746,0.0000068393565,0.00008296895,0.000002016588,0.000103046375,0.000082319035,0.9926362,0.000038592374,0.00022349868,0.0063054156],"study_design_scores_gemma":[0.00036876017,0.0002521828,0.0010715609,0.000025661884,0.000019003577,0.00008095447,0.000058495818,0.00007721182,0.963266,0.00007818142,0.03462072,0.00008127225],"about_ca_topic_score_codex":0.0000015847196,"about_ca_topic_score_gemma":0.000008702161,"teacher_disagreement_score":0.22413775,"about_ca_system_score_codex":0.000012889181,"about_ca_system_score_gemma":0.00014040005,"threshold_uncertainty_score":0.3155049},"labels":[],"label_agreement":null},{"id":"W2795791084","doi":"10.1002/cpmo.40","title":"Engineering Point Mutant and Epitope‐Tagged Alleles in Mice Using Cas9 RNA‐Guided Nuclease","year":2018,"lang":"en","type":"article","venue":"Current Protocols in Mouse Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Toronto Centre for Phenogenomics","funders":"National Institutes of Health; Ontario Genomics; Genome Canada","keywords":"Biology; Cas9; Point mutation; Guide RNA; Genetics; Epitope; Nuclease; CRISPR; Computational biology; Subgenomic mRNA; Genome editing; Directed evolution; Gene; Mutant; Molecular biology; Antibody","score_opus":0.03066246127422577,"score_gpt":0.3893431658034489,"score_spread":0.3586807045292231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795791084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864976,0.000536799,0.004783689,0.000021692724,0.00016386033,0.007939535,0.000014606414,0.000019859428,0.000022354767],"genre_scores_gemma":[0.9931209,0.000111962516,0.0023652876,0.00003423105,0.0003160644,0.0039862185,0.000021335216,0.00003433954,0.000009643963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867785,0.00006695125,0.00036428805,0.00045267763,0.0000486078,0.0003896074],"domain_scores_gemma":[0.9995448,0.0000149054285,0.000060578444,0.0002506307,0.000043664088,0.00008543318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028191792,0.00021837467,0.00023446584,0.00014352928,0.000034110624,0.000018391887,0.00017605972,0.00017827634,0.000012573964],"category_scores_gemma":[0.0001674243,0.00021847375,0.00004045949,0.000116653624,0.00009873264,0.0000056694685,0.00015246026,0.00016789863,0.0000036488834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075329444,0.00006577438,0.0039265235,0.00008208998,0.000009758098,0.0000045116253,0.00010394981,0.00040402255,0.9916851,0.000064176005,0.000040479397,0.0035383073],"study_design_scores_gemma":[0.0018660808,0.00035046056,0.0017396818,0.00018182296,0.000006291583,0.000042679258,0.000046754198,0.0078073665,0.9666299,0.000048786962,0.020812467,0.00046769783],"about_ca_topic_score_codex":0.00004630191,"about_ca_topic_score_gemma":0.000097242344,"teacher_disagreement_score":0.025055168,"about_ca_system_score_codex":0.000037828595,"about_ca_system_score_gemma":0.000046565754,"threshold_uncertainty_score":0.89091015},"labels":[],"label_agreement":null},{"id":"W2796520106","doi":"10.1016/j.bdq.2018.03.002","title":"Effect of endogenous reference genes on digital PCR assessment of genetically engineered canola events","year":2018,"lang":"en","type":"article","venue":"Biomolecular Detection and Quantification","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Digital polymerase chain reaction; Reference genes; Canola; Gene; Biology; Real-time polymerase chain reaction; Computational biology; Genetics; Polymerase chain reaction; Botany","score_opus":0.015536551634984264,"score_gpt":0.30806100475735326,"score_spread":0.292524453122369,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796520106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82987183,0.0002747595,0.16931918,0.000004882194,0.00009730295,0.0001662355,0.000018898487,0.000008840226,0.00023803618],"genre_scores_gemma":[0.9994204,0.000113200826,0.00032165754,0.0000047680137,0.00004533063,0.000013608634,0.00004630437,0.000013766433,0.000020947706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992748,0.000046733487,0.00020916048,0.0002381649,0.00012576459,0.000105373176],"domain_scores_gemma":[0.9994998,0.0000133080375,0.00008031464,0.00025785706,0.00010375569,0.000044965596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015671006,0.00011535125,0.000121885205,0.000074438074,0.00003817404,0.000010186773,0.0000706546,0.00009546755,0.0000033560473],"category_scores_gemma":[0.000050836185,0.00010772398,0.000048093236,0.000094580515,0.0000612693,0.0000028090392,0.000025181474,0.0000339559,0.0000018754308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007262505,0.000030771458,0.0003147244,0.000047045054,0.0000320655,3.2949697e-7,0.000009218072,0.000050826864,0.9628524,0.000040912968,0.0000014550094,0.036547605],"study_design_scores_gemma":[0.0003185021,0.001954045,0.005167054,0.000014788976,0.000023528599,0.000014059548,0.000005899896,0.0013984327,0.99030995,0.000003843005,0.0006898712,0.000099992416],"about_ca_topic_score_codex":0.0000105520885,"about_ca_topic_score_gemma":0.0000049841815,"teacher_disagreement_score":0.16954856,"about_ca_system_score_codex":0.000007945296,"about_ca_system_score_gemma":0.000019633308,"threshold_uncertainty_score":0.43928564},"labels":[],"label_agreement":null},{"id":"W2796765042","doi":"10.1089/hum.2018.018","title":"CRISPR/Cas9 Inhibits Multiple Steps of HIV-1 Infection","year":2018,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Cas9; CRISPR; Biology; Provirus; DNA; Plasmid; Virology; Gene; Genome editing; Molecular biology; Genetics; Genome","score_opus":0.01779815648448066,"score_gpt":0.3188524716163099,"score_spread":0.30105431513182923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796765042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98758024,0.0006251067,0.010661366,0.000013725153,0.00015399134,0.00013212519,0.0000075668777,0.000019685689,0.00080618914],"genre_scores_gemma":[0.99801016,0.00038047764,0.00048715321,0.000060777253,0.00059713755,0.000010673927,0.000049835522,0.000025915804,0.00037787354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937576,0.000022864542,0.00016027954,0.00020477216,0.00007825856,0.00015808847],"domain_scores_gemma":[0.9995401,0.0000038085195,0.000049277456,0.00029190906,0.00007264589,0.000042241587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000091783535,0.000119611206,0.00010507407,0.000046331657,0.00007143304,0.000008266715,0.00008666898,0.00008952724,0.000073633615],"category_scores_gemma":[0.00000926161,0.00011807587,0.000071540926,0.000060909693,0.00006859566,0.0000021094465,0.000037064743,0.0000428253,0.0000166164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000397827,0.000048127527,0.0062503796,0.000006804036,0.00003310194,2.0349059e-7,0.00012369185,0.0000866666,0.98897403,0.000015771899,0.0008981383,0.0035233153],"study_design_scores_gemma":[0.0006989019,0.0005479515,0.022609707,0.000005844125,0.000004429381,0.000004865336,0.000008925784,0.000053248445,0.95298827,0.000043841264,0.022902196,0.00013182282],"about_ca_topic_score_codex":0.000031665775,"about_ca_topic_score_gemma":0.00010735651,"teacher_disagreement_score":0.03598575,"about_ca_system_score_codex":0.000005832134,"about_ca_system_score_gemma":0.000013287052,"threshold_uncertainty_score":0.48149943},"labels":[],"label_agreement":null},{"id":"W2796961959","doi":"10.1038/s41467-018-03927-0","title":"Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; National Research Foundation of Korea; National Research Foundation; Universities Space Research Association","keywords":"CRISPR; Nucleic acid; Cas9; Genome editing; DNA; Endonuclease; Trans-activating crRNA; Computational biology; Cleavage (geology); Guide RNA; Nucleic acid structure; Gene; Biology; Chemistry; RNA; Biochemistry","score_opus":0.010781154812494191,"score_gpt":0.31796894647736074,"score_spread":0.30718779166486654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796961959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9691961,0.0053778896,0.019357534,0.00094514154,0.00034589152,0.00029810035,0.00004126574,0.00004398008,0.0043941056],"genre_scores_gemma":[0.9863865,0.00039887935,0.012591452,0.00012697474,0.0002165205,0.000010776002,0.00016899379,0.000019682293,0.00008024812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999349,0.000051553827,0.00021128042,0.00017898357,0.00009272002,0.00011648815],"domain_scores_gemma":[0.9981736,0.000020251464,0.000093323004,0.0013980601,0.00025748037,0.000057311572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013383766,0.0001111669,0.0001082467,0.00005363835,0.00015280061,0.000016414637,0.00057761715,0.00023208898,0.000011290222],"category_scores_gemma":[0.0001649079,0.000116079354,0.00006709762,0.00015189718,0.00020887103,0.0000057949405,0.00031518284,0.00025975303,0.000010137451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023425991,0.00005553017,0.00087465026,0.000010032311,0.000027150107,1.8403055e-7,0.00013595376,0.000012098185,0.9923071,0.0009907458,0.002498311,0.0030648215],"study_design_scores_gemma":[0.00025681988,0.00016212297,0.02184126,0.000011205826,0.000024175486,0.0000061307846,0.00009861203,0.00047547935,0.88276917,0.0001677657,0.09402971,0.00015755376],"about_ca_topic_score_codex":0.000048320762,"about_ca_topic_score_gemma":0.00053684396,"teacher_disagreement_score":0.10953793,"about_ca_system_score_codex":0.000016616403,"about_ca_system_score_gemma":0.000047134294,"threshold_uncertainty_score":0.47335786},"labels":[],"label_agreement":null},{"id":"W2798991228","doi":"10.1101/305516","title":"3 minutes to precisely measure morphogen concentration","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Agence Nationale de la Recherche; Natural Sciences and Engineering Research Council of Canada; Mitacs; Infrastructures en Biologie Santé et Agronomie","keywords":"Morphogen; Drosophila embryogenesis; Biology; Mitosis; Transcription factor; Transcription (linguistics); Cell biology; Gap gene; Genetics; Embryo; Embryogenesis; Gene","score_opus":0.010714027529401655,"score_gpt":0.24347919551883548,"score_spread":0.23276516798943384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2798991228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96182007,0.0030005763,0.032282446,0.0001506738,0.0014700296,0.0008675239,0.0002500238,0.00012430715,0.00003435322],"genre_scores_gemma":[0.9886138,0.00017442663,0.009084638,0.00023545591,0.0015728422,0.00017589827,0.0000028093693,0.0001163669,0.000023790284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997802,0.00006073712,0.00037078795,0.0009841771,0.0002921726,0.00049008074],"domain_scores_gemma":[0.997847,0.0000096338135,0.00014117488,0.0011683878,0.0005122349,0.00032152905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032875704,0.00047497472,0.00032977064,0.000080966296,0.00009224735,0.00013027321,0.0005044895,0.0005748979,0.000033476685],"category_scores_gemma":[0.0002335791,0.00053949433,0.00014684856,0.00018307829,0.00006502606,0.0000050535673,0.0004477083,0.00024686859,0.00008178414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040274386,0.00003975927,0.0018107645,0.00009213101,0.00012373793,0.0000055370583,0.0000071461964,0.00048419685,0.9913878,0.000011757761,0.0059924163,0.000004466762],"study_design_scores_gemma":[0.00027589995,0.0001253656,0.017153643,0.00014122191,0.000066407796,2.3294287e-8,0.0000012336723,0.00015271231,0.9517682,5.3216496e-7,0.029676957,0.0006377559],"about_ca_topic_score_codex":0.00001451385,"about_ca_topic_score_gemma":0.0000047862404,"teacher_disagreement_score":0.039619565,"about_ca_system_score_codex":0.00006966637,"about_ca_system_score_gemma":0.00033615506,"threshold_uncertainty_score":0.9997057},"labels":[],"label_agreement":null},{"id":"W2799065786","doi":"10.1101/309302","title":"CRISPRCloud2: A cloud-based platform for deconvolving CRISPR screen data","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institute of General Medical Sciences; Huffington Foundation; Parkinson's Foundation; Houston Endowment; Cancer Prevention and Research Institute of Texas; Division of Mathematical Sciences; National Science Foundation","keywords":"CRISPR; Computer science; Cloud computing; Prioritization; Visualization; Data mining; Interface (matter); Feature (linguistics); Data science; Operating system; Engineering; Gene; Biology","score_opus":0.02527155925417372,"score_gpt":0.2906401319897265,"score_spread":0.26536857273555275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799065786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5214575,0.0045214063,0.46454635,0.00017383588,0.0032923417,0.0017942475,0.00389329,0.00029893583,0.000022113356],"genre_scores_gemma":[0.95467484,0.00020326332,0.040294472,0.00040495006,0.0038180235,0.00025500628,0.000051108644,0.00028506157,0.000013274917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961826,0.00004819528,0.00066506554,0.0018998598,0.00031908014,0.00088520267],"domain_scores_gemma":[0.9946589,0.000060149687,0.00033225477,0.0040005953,0.0005958955,0.0003522239],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009182175,0.000776436,0.00059977546,0.00018048614,0.00023014034,0.00023716758,0.0018788554,0.0009480838,0.00003340803],"category_scores_gemma":[0.0006195745,0.0008831331,0.00023986166,0.00018483042,0.00015323538,0.000015770413,0.0016830821,0.00044824943,0.000028123213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001835442,0.00013395146,0.0015775447,0.0007307595,0.00039321237,0.000011524315,0.000004312183,0.0007327833,0.9792453,0.0000636657,0.016911708,0.000011682783],"study_design_scores_gemma":[0.0012627754,0.00024681428,0.0035225635,0.00030139726,0.00025988862,4.2363446e-8,0.000003618894,0.01070047,0.91456276,0.0000034300915,0.067750774,0.0013854416],"about_ca_topic_score_codex":0.000049004815,"about_ca_topic_score_gemma":0.000021161404,"teacher_disagreement_score":0.43321738,"about_ca_system_score_codex":0.00008647681,"about_ca_system_score_gemma":0.0007866363,"threshold_uncertainty_score":0.99936193},"labels":[],"label_agreement":null},{"id":"W2800153285","doi":"10.1016/j.jgg.2018.02.009","title":"Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells","year":2018,"lang":"en","type":"letter","venue":"Journal of genetics and genomics/Journal of Genetics and Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Health, British Columbia; National Natural Science Foundation of China; Eye Hospital Wenzhou Medical University; Wenzhou Medical University","keywords":"CRISPR; Cas9; Genome editing; Computational biology; Biology; Human genome; Mutagenesis; Genome engineering; Palindrome; Cleavage (geology); DNA; Genetics; Genome; Molecular biology; Cell biology; Mutation; Gene","score_opus":0.009713587251680304,"score_gpt":0.25541684500050355,"score_spread":0.24570325774882323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800153285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9483571,0.038484003,0.0066802087,0.0041607977,0.0017635609,0.0002860553,0.00021679702,0.000002566694,0.000048880378],"genre_scores_gemma":[0.8390464,0.10557894,0.01046146,0.024085728,0.018934244,0.000007526525,0.00026280098,0.00045666617,0.0011662422],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.995638,0.00013105877,0.0023536333,0.0006022471,0.0005164251,0.00075861893],"domain_scores_gemma":[0.9963064,0.00007413766,0.0020738698,0.0004846395,0.00067644444,0.00038450892],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010046521,0.00079299265,0.001315033,0.00059338333,0.00018563618,0.00022282131,0.0006800664,0.0011949453,0.000043779582],"category_scores_gemma":[0.000033307686,0.0007884641,0.00045627618,0.00011961054,0.00027521807,0.000013886342,0.00035226866,0.0016263337,0.0000019103427],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027360691,0.00013846447,0.0013938284,0.0002693862,0.0008399845,0.00041292465,0.00054392207,0.003130337,0.7695278,0.0000014784714,0.21851487,0.0049534105],"study_design_scores_gemma":[0.0049545043,0.0051653218,0.005003238,0.00029644166,0.0008424756,0.0038254396,0.0003932649,0.00041027143,0.23976661,0.00032872014,0.7374517,0.0015620427],"about_ca_topic_score_codex":0.00001610352,"about_ca_topic_score_gemma":0.000031310767,"teacher_disagreement_score":0.5297612,"about_ca_system_score_codex":0.00013186825,"about_ca_system_score_gemma":0.00051179354,"threshold_uncertainty_score":0.99945664},"labels":[],"label_agreement":null},{"id":"W2800614641","doi":"10.1101/321208","title":"Versatile and robust genome editing with <i>Streptococcus thermophilus</i> CRISPR1-Cas9","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Université Laval; Centre Hospitalier Universitaire de Sherbrooke; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Agence Nationale de la Recherche; University of California, San Francisco; Banting Research Foundation","keywords":"Genome editing; Genome; Phenotype; CRISPR; Cytosine; Complement (music); Synthetic biology; DNA","score_opus":0.0077479204257895435,"score_gpt":0.22135748753631976,"score_spread":0.21360956711053022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800614641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98256785,0.0023902142,0.013238222,0.000088305205,0.00062370475,0.0006716467,0.00021558418,0.00013795921,0.00006650844],"genre_scores_gemma":[0.99123025,0.00042953575,0.0057571954,0.00014212259,0.002110419,0.0001458148,0.000003185067,0.00017280344,0.000008645109],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99763536,0.0000521825,0.00034881904,0.0011399118,0.0002487574,0.0005749533],"domain_scores_gemma":[0.99804896,0.000014286161,0.0002236127,0.0011372565,0.00030609244,0.0002697722],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028631018,0.00060082215,0.0004086225,0.000120987366,0.00016044112,0.0001609264,0.00039545805,0.00053392036,0.00003281184],"category_scores_gemma":[0.00007472197,0.0005987697,0.00010070303,0.0001652981,0.00020455215,0.000008608817,0.00064891967,0.00041796133,0.000014940424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043291868,0.000044826138,0.0041449745,0.00026452472,0.00022517478,0.000027535098,0.000014116291,0.0012594804,0.9934422,0.000010367789,0.0005199517,0.0000035911],"study_design_scores_gemma":[0.0010065573,0.00038246493,0.053570632,0.00030874254,0.0002143791,2.4906487e-7,0.000015878277,0.0004893284,0.9215162,8.598747e-7,0.021072378,0.0014223327],"about_ca_topic_score_codex":0.000023341157,"about_ca_topic_score_gemma":0.0000066066254,"teacher_disagreement_score":0.07192597,"about_ca_system_score_codex":0.00004981271,"about_ca_system_score_gemma":0.00021719807,"threshold_uncertainty_score":0.99964637},"labels":[],"label_agreement":null},{"id":"W2800660178","doi":"10.1080/15476286.2018.1456300","title":"Live-cell imaging reveals the dynamics and function of single-telomere TERRA molecules in cancer cells","year":2018,"lang":"en","type":"article","venue":"RNA Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Austrian Science Fund","keywords":"Telomere; Biology; Heterochromatin; Genome instability; Telomere-binding protein; RNA; Live cell imaging; Genetics; Cell biology; DNA; Gene; Chromosome; DNA damage; Cell; DNA-binding protein; Transcription factor","score_opus":0.0065669561525340155,"score_gpt":0.27467372251758476,"score_spread":0.26810676636505076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800660178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891971,0.0032995099,0.0063202446,0.00010547051,0.000203314,0.00007990237,0.000015545886,0.0000040457835,0.0007748636],"genre_scores_gemma":[0.9989632,0.0003668525,0.00026799573,0.00012105704,0.0001305379,0.0000073394604,0.000015524292,0.000010015192,0.00011748912],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994778,0.00003438729,0.00013396789,0.00018158223,0.000022589777,0.00014968622],"domain_scores_gemma":[0.9997339,0.000012129744,0.000047427035,0.00014996679,0.00003521202,0.000021332522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008708568,0.000086968575,0.00009684771,0.00003133673,0.000025941632,0.0000046737396,0.00008271791,0.00007593259,0.000023707507],"category_scores_gemma":[0.000011952032,0.00006759739,0.00002488266,0.00004873972,0.00013683007,0.0000013109262,0.000070498034,0.000048407797,0.0000016426759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021713875,0.000015704514,0.011279367,0.000014479583,0.000009339578,3.104184e-7,0.00005761156,0.00004147857,0.97601503,0.000049616614,0.000104874845,0.012390462],"study_design_scores_gemma":[0.00032131028,0.0003079432,0.015918227,0.000015273248,0.000017236858,0.0000045949296,0.00019328385,0.0019679996,0.9792426,0.00009399118,0.0017802953,0.00013721279],"about_ca_topic_score_codex":0.00008166188,"about_ca_topic_score_gemma":0.00022171364,"teacher_disagreement_score":0.012253249,"about_ca_system_score_codex":0.000009526817,"about_ca_system_score_gemma":0.000012867721,"threshold_uncertainty_score":0.27565417},"labels":[],"label_agreement":null},{"id":"W2801424073","doi":"10.3389/fpls.2018.00617","title":"Application of CRISPR/Cas9 Genome Editing Technology for the Improvement of Crops Cultivated in Tropical Climates: Recent Progress, Prospects, and Challenges","year":2018,"lang":"en","type":"review","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":231,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada)","funders":"Krishi Gobeshona Foundation; West Virginia University; World Bank Group","keywords":"CRISPR; Genome editing; Transcription activator-like effector nuclease; Biology; Cas9; Biotechnology; Genome; Population; Zinc finger nuclease; Computational biology; Genetics; Gene; Medicine","score_opus":0.01706400837666799,"score_gpt":0.31478185110960355,"score_spread":0.29771784273293556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801424073","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005615693,0.9878763,0.010068852,0.000056940702,0.00018954992,0.0011643373,0.000070872156,0.0000044056223,0.0000071656837],"genre_scores_gemma":[0.0039901286,0.9906087,0.004991891,0.0000019758709,0.000063767075,0.00029540912,0.000035997655,0.000010137539,0.000001988021],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99885345,0.000010085687,0.000381428,0.00040325354,0.00011086674,0.00024092563],"domain_scores_gemma":[0.9994179,0.000013564846,0.00021197162,0.00026276932,0.00007048128,0.000023294055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036882947,0.00014602688,0.00039802684,0.00017792416,0.000037768878,0.000007397722,0.00037289248,0.00016277067,1.8516147e-7],"category_scores_gemma":[0.000107427724,0.00010318764,0.000037679198,0.00030845767,0.0005419505,0.0000030771898,0.00014910645,0.00009262295,6.443353e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028631222,0.00008346463,0.0019766383,0.0072032446,0.000041264833,7.6220977e-7,0.000110456116,0.00001310617,0.0074499855,0.00015610635,0.000080464364,0.98285586],"study_design_scores_gemma":[0.0006015479,0.00075543835,0.0013859168,0.0026456492,0.000103569604,0.000022177213,0.00060819706,0.0015775652,0.03754824,0.00012851578,0.9542076,0.00041558503],"about_ca_topic_score_codex":0.000002253647,"about_ca_topic_score_gemma":0.000010939846,"teacher_disagreement_score":0.9824403,"about_ca_system_score_codex":0.00003542313,"about_ca_system_score_gemma":0.000086966,"threshold_uncertainty_score":0.42078698},"labels":[],"label_agreement":null},{"id":"W2802027241","doi":"10.1007/978-981-10-8372-3_14","title":"Chemical and CRISPR/Cas9 Tools for Functional Characterization of RNA Helicases","year":2018,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Computational biology; Helicase; Biology; RNA; Genetics; Gene","score_opus":0.01936585931145574,"score_gpt":0.27290626866661793,"score_spread":0.2535404093551622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802027241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44038677,0.0020649012,0.43161583,0.00030217078,0.0011667275,0.0018212773,0.0016250052,0.0000772729,0.12094004],"genre_scores_gemma":[0.5499038,0.0017380149,0.005010883,0.0005173651,0.0043754023,0.00009502523,0.009031167,0.00020949816,0.4291188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994099,0.000001595278,0.00017814373,0.00024958904,0.0000673143,0.00009346707],"domain_scores_gemma":[0.999603,0.00001434943,0.00006460267,0.00015879355,0.00011601785,0.000043258828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038366587,0.0001548103,0.000158235,0.000028948443,0.00001786,0.000014193444,0.000048614264,0.00025177377,0.0001988141],"category_scores_gemma":[0.000033378266,0.00015081729,0.00008239307,0.000005580351,0.000058589507,0.0000021367835,0.000055918576,0.000038482383,0.0000030120755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054319604,0.00000613675,0.000002223709,0.00006914728,0.000050531362,1.8010009e-7,0.0000040437258,7.0838007e-7,0.9935367,0.00098509,0.0016363357,0.0036545973],"study_design_scores_gemma":[0.00021382018,0.00013243301,0.000059072572,0.000026598984,0.000038938677,0.000009936075,0.0000026838957,0.000026535818,0.80650747,0.00013161887,0.19267774,0.00017318303],"about_ca_topic_score_codex":4.492277e-7,"about_ca_topic_score_gemma":0.0000010048878,"teacher_disagreement_score":0.42660496,"about_ca_system_score_codex":0.0000042519155,"about_ca_system_score_gemma":0.000024729827,"threshold_uncertainty_score":0.61501503},"labels":[],"label_agreement":null},{"id":"W2802269419","doi":"10.1038/s41525-018-0046-7","title":"Clinical testing of BRCA1 and BRCA2: a worldwide snapshot of technological practices","year":2018,"lang":"en","type":"article","venue":"npj Genomic Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; National Human Genome Research Institute; National Health and Medical Research Council; Florida Breast Cancer Foundation","keywords":"Genetic testing; Medicine; Snapshot (computer storage); Computer science; Database; Internal medicine","score_opus":0.04580133963204189,"score_gpt":0.39198922757549576,"score_spread":0.3461878879434539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802269419","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919841,0.0024070311,0.0016677589,0.00026539914,0.00009827256,0.00010334748,0.0000028158634,0.0000077522445,0.0034635074],"genre_scores_gemma":[0.9915472,0.00029203534,0.007593245,0.00009348327,0.00037980158,0.000002735389,0.00000929973,0.0000096774065,0.00007249333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990701,0.00003535191,0.00041919167,0.00025230588,0.00008506124,0.00013795806],"domain_scores_gemma":[0.9991409,0.00012996234,0.00029201165,0.00027989966,0.00009476327,0.00006246935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071408215,0.000100284284,0.00025306045,0.000049764454,0.00002214545,0.0000017659719,0.00014392695,0.00013099262,0.00005944802],"category_scores_gemma":[0.0024562303,0.00007895782,0.00002981275,0.00010084459,0.0006505864,0.0000013777951,0.000120613644,0.00009809374,0.0000012048242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051453833,0.000026716696,0.029669162,0.000040681796,0.000041437488,0.0000015392966,0.000045840847,0.0000042554548,0.9501521,0.000058345475,0.00039744415,0.019511031],"study_design_scores_gemma":[0.0027152947,0.004899969,0.20844814,0.00027349053,0.00019565523,0.00015377927,0.0006147053,0.00080756145,0.70754045,0.00031445894,0.07366395,0.00037253127],"about_ca_topic_score_codex":0.000024835792,"about_ca_topic_score_gemma":0.0000135620085,"teacher_disagreement_score":0.24261163,"about_ca_system_score_codex":0.0000034458915,"about_ca_system_score_gemma":0.000035089623,"threshold_uncertainty_score":0.32198063},"labels":[],"label_agreement":null},{"id":"W2802473049","doi":"10.1016/j.omtn.2018.04.017","title":"Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Natur og Univers, Det Frie Forskningsråd; Stanford Maternal and Child Health Research Institute; Sundhed og Sygdom, Det Frie Forskningsråd; Amon G. Carter Foundation; Children's Health Research Institute; California Institute for Regenerative Medicine","keywords":"Biology; Progenitor cell; Haematopoiesis; Electroporation; Genome editing; Stem cell; Cell biology; Transduction (biophysics); Population; Molecular biology; CRISPR; Genetics; Gene; Medicine","score_opus":0.01246488081359751,"score_gpt":0.2931785660832801,"score_spread":0.28071368526968254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802473049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9447682,0.0024198862,0.051919907,0.000038181817,0.00020057452,0.00051868317,0.000006802712,0.000046375324,0.00008139267],"genre_scores_gemma":[0.98245364,0.000058368227,0.016443714,0.0001790853,0.0005192401,0.000061081875,0.000038638536,0.000102370876,0.0001438411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985007,0.000041665848,0.00034393932,0.00054477586,0.00014670166,0.0004222386],"domain_scores_gemma":[0.99924093,0.000008812623,0.00011147352,0.00041101885,0.000110178065,0.00011759598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002622856,0.00027565542,0.00022316801,0.00004936863,0.00028731997,0.00006709826,0.00018747256,0.00017505324,0.000009658954],"category_scores_gemma":[0.000019186167,0.00027971683,0.00013111629,0.00007938053,0.000094061565,0.000005352461,0.00010849455,0.00008531226,0.0000031416719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037487527,0.000025273888,0.0004598602,0.00004408722,0.00007812533,0.0000071830004,0.0003411327,0.00006213321,0.9940829,0.00003544709,0.00009346611,0.004732902],"study_design_scores_gemma":[0.0007582918,0.0004867545,0.00016126016,0.000022688922,0.00002380388,0.000040203486,0.0001496077,0.00048682536,0.9894814,0.00005717004,0.007983457,0.00034857492],"about_ca_topic_score_codex":0.000007853792,"about_ca_topic_score_gemma":0.0000021953247,"teacher_disagreement_score":0.037685465,"about_ca_system_score_codex":0.000016168906,"about_ca_system_score_gemma":0.000022128621,"threshold_uncertainty_score":0.9999655},"labels":[],"label_agreement":null},{"id":"W2802788852","doi":"10.3389/fcell.2018.00046","title":"Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases","year":2018,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; New York State Department of Health - Wadsworth Center; Crowley Family Foundation; Research to Prevent Blindness; National Cancer Institute; National Institutes of Health; Foundation Fighting Blindness","keywords":"CRISPR; Genome editing; Genome; Biology; Bioinformatics; Medicine; Computational biology; Genetics; Gene","score_opus":0.019670301646002256,"score_gpt":0.3141569921370419,"score_spread":0.29448669049103965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802788852","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00045177515,0.9699117,0.028361682,0.000014980093,0.00047565103,0.00050529814,0.00018552349,0.0000031412778,0.00009027245],"genre_scores_gemma":[0.00083894824,0.9850611,0.012706325,0.000040080016,0.00017969866,0.00012920798,0.0009219625,0.00002156546,0.0001010748],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990245,0.000048591784,0.0003641294,0.00032415995,0.000033800727,0.00020478932],"domain_scores_gemma":[0.99967635,0.000054516935,0.0000784196,0.00011812337,0.000020373182,0.000052238192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018012969,0.00019680933,0.0005179564,0.00010994962,0.000040116345,0.000005643297,0.00013676945,0.0002012495,0.0000038615844],"category_scores_gemma":[0.000037244416,0.00014408317,0.00014690217,0.00008985955,0.00007729192,0.0000010956564,0.00006423987,0.00005229032,0.0000015109784],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011839044,0.000046021552,0.0014304431,0.004575446,0.00016024374,0.0000012242635,0.0001635474,0.0000050377066,0.0014206395,0.0000031849393,0.024132151,0.96794367],"study_design_scores_gemma":[0.000102516504,0.00008303902,0.000114892675,0.0001931172,0.00006540617,0.000006341471,0.00005364127,0.000002509263,0.0011013766,0.00002005613,0.9980598,0.00019729548],"about_ca_topic_score_codex":0.000003563622,"about_ca_topic_score_gemma":0.000009677616,"teacher_disagreement_score":0.9739277,"about_ca_system_score_codex":0.000016448934,"about_ca_system_score_gemma":0.000120901335,"threshold_uncertainty_score":0.58755416},"labels":[],"label_agreement":null},{"id":"W2804414244","doi":"10.1016/j.stem.2018.05.001","title":"Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males","year":2018,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia; Medical Research Council; Medical Research Council Canada; Wellcome Trust","keywords":"XIST; Biology; X-inactivation; Homeobox protein NANOG; Epiblast; X chromosome; Genetics; Chromatin; Dosage compensation; Embryonic stem cell; Gene silencing; Cell biology; Gene; Induced pluripotent stem cell; Gastrulation","score_opus":0.008551255189225943,"score_gpt":0.24056340200706083,"score_spread":0.23201214681783489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804414244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906057,0.0015111369,0.0036731842,0.0000211661,0.0002938943,0.00017478352,0.000029544008,0.0000141336095,0.003676422],"genre_scores_gemma":[0.9976331,0.00036396587,0.00043578056,0.000062527106,0.00019988157,0.000018775845,0.00006777576,0.000026648728,0.0011915566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990175,0.000029307346,0.0002178863,0.00037025602,0.00010744695,0.00025761608],"domain_scores_gemma":[0.9995478,0.000011992305,0.00005304609,0.00026498322,0.000046369565,0.00007582319],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000659011,0.00017217676,0.00013982407,0.00008027215,0.000042639353,0.000020668129,0.00016273062,0.00011680099,0.000058092213],"category_scores_gemma":[0.0000020567131,0.000175325,0.000052399784,0.0001488415,0.000051132407,0.0000050664758,0.00005108048,0.000091456815,0.000043620188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031404183,0.00007355133,0.0006766352,0.00003148818,0.000010273891,0.0000063929033,0.0008855549,0.00024988904,0.996487,0.0000011190058,0.00039296562,0.0011537219],"study_design_scores_gemma":[0.00055246823,0.00020293254,0.005477947,0.000021957414,0.000007981481,0.0000012924255,0.0003130585,0.00011335709,0.9804832,0.00004228916,0.012555762,0.00022780064],"about_ca_topic_score_codex":0.00016531041,"about_ca_topic_score_gemma":0.00013277029,"teacher_disagreement_score":0.01600385,"about_ca_system_score_codex":0.00001884358,"about_ca_system_score_gemma":0.000048246922,"threshold_uncertainty_score":0.71495456},"labels":[],"label_agreement":null},{"id":"W2805012591","doi":"10.19070/2332-290x-si02002","title":"A Review of Personalised Molecular Medicine for the Treatment of Corneal Disorders","year":2015,"lang":"en","type":"review","venue":"International Journal of Ophthalmology & Eye Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"","keywords":"Transcription activator-like effector nuclease; CRISPR; Genome editing; Cas9; RNA interference; Gene silencing; Biology; Gene; Computational biology; Genetics; Gene expression; Small interfering RNA; Genetic enhancement; DNA; RNA","score_opus":0.045286575181509574,"score_gpt":0.4554096337984927,"score_spread":0.4101230586169831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805012591","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005794799,0.99655527,0.0012404004,0.00023242226,0.00084660674,0.00031276298,0.0000353863,5.615045e-7,0.00019712493],"genre_scores_gemma":[0.0037987055,0.99534833,0.0005136901,0.00002623096,0.0002177019,0.000015436615,0.000020701227,0.000011940718,0.00004723108],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99855053,0.000049287893,0.00067856634,0.00018774963,0.00039793647,0.00013591388],"domain_scores_gemma":[0.99788755,0.00008893323,0.0007996447,0.00022410681,0.0009330811,0.00006667422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00085428555,0.00017606694,0.0007136127,0.00014586053,0.000021398502,0.000004411064,0.00097576604,0.000083611514,0.000026777081],"category_scores_gemma":[0.0003940999,0.000102392674,0.00044781575,0.00015796133,0.0005931455,0.000004241799,0.000057178644,0.00006819459,3.0526854e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024216146,0.00064528803,0.00014920702,0.0141224675,0.0027354327,0.00016937949,0.00032690936,0.0003100257,0.01191132,0.00033527066,0.0014999402,0.9675526],"study_design_scores_gemma":[0.00082666246,0.0030533539,0.000048225018,0.012313235,0.000806489,0.0034271267,0.000048377162,0.00002663278,0.0011474914,0.00007672538,0.97804767,0.00017802582],"about_ca_topic_score_codex":0.000010688765,"about_ca_topic_score_gemma":4.2790205e-7,"teacher_disagreement_score":0.9765477,"about_ca_system_score_codex":0.000055184813,"about_ca_system_score_gemma":0.0007375998,"threshold_uncertainty_score":0.4175452},"labels":[],"label_agreement":null},{"id":"W2805081247","doi":"10.1038/s41598-018-24690-8","title":"Targeted mutagenesis in wheat microspores using CRISPR/Cas9","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Plant Biotechnology Institute","funders":"National Research Council Canada; Agriculture and Agri-Food Canada; U.S. Department of Energy","keywords":"CRISPR; Microspore; Cas9; Genome editing; Biology; Doubled haploidy; Mutagenesis; Gene; Computational biology; Genetics; Genome; Ploidy; Biotechnology; Mutation; Stamen; Botany","score_opus":0.010005931413783612,"score_gpt":0.30342563674991374,"score_spread":0.29341970533613015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805081247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912158,0.00087964494,0.0040262057,0.000019948193,0.0033328047,0.00013414782,0.0000022081426,0.000016437169,0.00037280316],"genre_scores_gemma":[0.99576557,0.000007868652,0.002623957,0.000028692462,0.00024121284,0.000005203471,0.00004864968,0.000020282649,0.0012585489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985758,0.00001852511,0.00030491504,0.00062038045,0.00016091802,0.00031943948],"domain_scores_gemma":[0.9991095,0.00000255809,0.00007093919,0.00062541943,0.00011098323,0.00008059631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048722373,0.00013211192,0.00011987973,0.00011757798,0.00013668212,0.00008524642,0.000107762855,0.00009653398,0.0000693462],"category_scores_gemma":[0.00007548996,0.0001322497,0.000066103465,0.00027538073,0.00019007089,0.0000047446224,0.00009786341,0.00004531788,0.000008889152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073072133,0.000020912497,0.011010169,0.0000090361655,0.0000074409686,0.00007205474,0.000084867286,0.00038606592,0.9845127,0.0000012265467,0.0033796164,0.00050862523],"study_design_scores_gemma":[0.0000953262,0.00003271292,0.0048701293,0.000014680416,0.0000073194337,0.00016085169,0.00005138799,0.0004063699,0.95683837,0.00009165553,0.037260517,0.00017067877],"about_ca_topic_score_codex":0.000064304986,"about_ca_topic_score_gemma":0.00016575809,"teacher_disagreement_score":0.033880904,"about_ca_system_score_codex":0.000018349147,"about_ca_system_score_gemma":0.00009624047,"threshold_uncertainty_score":0.5392986},"labels":[],"label_agreement":null},{"id":"W2805282888","doi":"10.1016/j.tibtech.2018.04.008","title":"Building Capacity for a Global Genome Editing Observatory: Institutional Design","year":2018,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of General Medical Sciences; World Health Organization","keywords":"Observatory; Genome editing; Key (lock); Reflection (computer programming); Genome; Capacity building; Computer science; Biology; Political science; Gene; Genetics; Ecology","score_opus":0.03572064149874072,"score_gpt":0.32463120845913174,"score_spread":0.288910566960391,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805282888","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41986805,0.00024703683,0.5789299,0.0003109882,0.00028625454,0.00008373453,0.000027718203,0.00004770705,0.00019860532],"genre_scores_gemma":[0.845468,0.000013427246,0.1538844,0.00008002642,0.00044611734,0.000035158162,0.000028103823,0.000010427252,0.00003432855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991083,0.000014011451,0.00016570651,0.0003353398,0.000053493615,0.00032314015],"domain_scores_gemma":[0.9996525,0.0000065052295,0.000037257054,0.0002316407,0.000036943035,0.00003512182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017082531,0.00013322063,0.00012623006,0.00010244918,0.00007963465,0.000008225574,0.00021702718,0.00038248033,0.00000909784],"category_scores_gemma":[0.0000977683,0.00014456564,0.00005066966,0.00026347552,0.00022804491,0.0000027588057,0.00009835011,0.00008900965,0.0000024576282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052268097,0.000038979524,0.00081967516,0.000012414174,0.00003412539,0.0000028867182,0.000015032295,0.0010805288,0.9380788,0.013773762,0.0003856053,0.045705922],"study_design_scores_gemma":[0.0011078798,0.00066405296,0.007861644,0.000017895747,0.000015653795,0.0000704026,0.000018368659,0.0023422963,0.8090911,0.002106363,0.17633556,0.00036879748],"about_ca_topic_score_codex":0.000011799311,"about_ca_topic_score_gemma":0.000088886154,"teacher_disagreement_score":0.42559996,"about_ca_system_score_codex":0.00004758042,"about_ca_system_score_gemma":0.000029321536,"threshold_uncertainty_score":0.5895216},"labels":[],"label_agreement":null},{"id":"W2805400981","doi":"10.1038/s41467-018-05092-w","title":"Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Streptococcus thermophilus; Virulence; Cas9; Genome; Biology; Genome editing; Computational biology; Genetics; Gene; Bacteria","score_opus":0.011122184902965036,"score_gpt":0.32220044906224143,"score_spread":0.3110782641592764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805400981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871194,0.008302129,0.001515908,0.00072459626,0.00010817601,0.00072960067,0.000048827173,0.00002056564,0.0014308483],"genre_scores_gemma":[0.99073535,0.0005844844,0.008215336,0.000092357775,0.00008697198,0.00010686737,0.00006296175,0.000020170899,0.00009547318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992321,0.000068480156,0.00024001386,0.00019449681,0.000094841045,0.00017006237],"domain_scores_gemma":[0.99839723,0.000019077172,0.000072809686,0.0013254343,0.00014161352,0.00004384221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017445307,0.00012722245,0.00014910215,0.00008577147,0.00007168709,0.000012214508,0.0005699986,0.00025964543,0.00001231753],"category_scores_gemma":[0.00017008785,0.00012698479,0.00006169842,0.00020470869,0.00016497665,0.0000050422764,0.00033761482,0.0003136329,0.00000612096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020897452,0.0001462467,0.006176881,0.000027426648,0.000023053952,7.1150055e-7,0.00021541517,0.000010474047,0.9915531,0.0001966187,0.00039007826,0.0012390908],"study_design_scores_gemma":[0.0005063593,0.00018656337,0.0602975,0.00009269206,0.000013976067,0.000009022481,0.00006194969,0.00011450039,0.90189755,0.000024947376,0.0366094,0.0001855535],"about_ca_topic_score_codex":0.00007128017,"about_ca_topic_score_gemma":0.0016115843,"teacher_disagreement_score":0.08965557,"about_ca_system_score_codex":0.0000148927875,"about_ca_system_score_gemma":0.000053575142,"threshold_uncertainty_score":0.51782894},"labels":[],"label_agreement":null},{"id":"W2805515939","doi":"10.1038/s41467-019-09148-3","title":"Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; University of Oxford; International Seafood Sustainability Foundation; Wellcome Trust","keywords":"Transfer RNA; Computational biology; RNA polymerase III; Synthetic biology; Cas9; CRISPR; RNA; Biology; Guide RNA; Function (biology); Computer science; Genetics; Gene; RNA polymerase","score_opus":0.009251791199604398,"score_gpt":0.3108032040619988,"score_spread":0.3015514128623944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805515939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9528892,0.041054416,0.001562446,0.00046765365,0.00010594761,0.00021556331,0.0000088076595,0.000028340739,0.0036676344],"genre_scores_gemma":[0.9853334,0.001984577,0.011497663,0.00007100569,0.00008623968,0.000016877508,0.00006606412,0.000021174725,0.00092302356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943465,0.000019842002,0.00013023168,0.00019724846,0.0000730622,0.00014495943],"domain_scores_gemma":[0.99902445,0.000019761676,0.00004754062,0.0008157198,0.000050204868,0.000042302123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010246679,0.000114078925,0.000094956325,0.000041955023,0.00022540818,0.000042137388,0.0003272563,0.0002040453,0.000009207795],"category_scores_gemma":[0.000025316873,0.00010597789,0.000033556036,0.00006161638,0.000047538924,0.000009428254,0.0003962807,0.00028092365,0.0000017929107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007257207,0.000027336406,0.00074457366,0.000022691958,0.00000916849,1.8041767e-7,0.00019861225,0.00006260126,0.9920471,0.0000592788,0.0010950802,0.005726137],"study_design_scores_gemma":[0.00028115558,0.00005554222,0.0019109023,0.00009255743,0.0000103923285,0.000017691982,0.00034185074,0.0008086693,0.7124362,0.000031137897,0.28379846,0.000215476],"about_ca_topic_score_codex":0.000003724523,"about_ca_topic_score_gemma":0.000032718144,"teacher_disagreement_score":0.28270337,"about_ca_system_score_codex":0.000011178794,"about_ca_system_score_gemma":0.000031012467,"threshold_uncertainty_score":0.43216527},"labels":[],"label_agreement":null},{"id":"W2806063849","doi":"10.1016/j.jogc.2018.01.003","title":"The Cement Spiral","year":2018,"lang":"en","type":"editorial","venue":"Journal of Obstetrics and Gynaecology Canada","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Cement; Spiral (railway); Metallurgy; Mechanical engineering","score_opus":0.004461627407692656,"score_gpt":0.24716040942989276,"score_spread":0.2426987820222001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806063849","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0073942537,0.0251202,0.00011119666,0.00006547404,0.9669203,0.00006115149,0.00003472166,8.0870524e-7,0.000291887],"genre_scores_gemma":[0.21676937,0.013535352,0.0005557634,0.00029466354,0.7638517,0.000010573542,0.00012013005,0.00010922616,0.004753251],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987967,0.000034700905,0.0004004393,0.00015617869,0.00035606572,0.00025592878],"domain_scores_gemma":[0.9981131,0.0007537677,0.00033602782,0.00019742448,0.00047508298,0.00012462914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031933544,0.00017131557,0.00023696305,0.00005378568,0.00013980281,0.000037263948,0.0003110319,0.00038570308,0.000018494777],"category_scores_gemma":[0.00474392,0.000121781006,0.000074022144,0.000072576164,0.00007733354,0.0000013020777,0.000116754876,0.00038265067,3.0184145e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000035902146,0.0000070989922,0.00017671105,0.000015417003,0.00013024796,0.000076957236,0.000005048643,0.00002464937,0.000052857078,0.0000025770207,0.98688525,0.012619618],"study_design_scores_gemma":[0.0004973644,0.0005274033,0.0008039129,0.0000031710767,0.000054590735,0.0000074477402,0.000033603268,0.000005827456,0.0003017081,0.000012292867,0.99761957,0.00013313774],"about_ca_topic_score_codex":0.0014820517,"about_ca_topic_score_gemma":0.02777102,"teacher_disagreement_score":0.20937511,"about_ca_system_score_codex":0.00019458264,"about_ca_system_score_gemma":0.0021470415,"threshold_uncertainty_score":0.9899696},"labels":[],"label_agreement":null},{"id":"W2806185321","doi":"10.1016/j.tibtech.2018.04.009","title":"Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges","year":2018,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of General Medical Sciences; World Health Organization","keywords":"Observatory; Genome editing; Genome; Key (lock); Global health; Political science; Biology; Sociology; Data science; Computer science; Genetics; Gene; Ecology; Law","score_opus":0.04060299428970559,"score_gpt":0.3284056560626236,"score_spread":0.287802661772918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806185321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9571263,0.0021784168,0.038090587,0.0011786572,0.000446904,0.000109709676,0.000046691563,0.00009012164,0.0007326192],"genre_scores_gemma":[0.97247183,0.00013125961,0.026559139,0.00007396015,0.0006466414,0.000034990688,0.000023068524,0.000017146964,0.000041938718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896026,0.000014184149,0.00017693537,0.00040666555,0.00005313641,0.00038880634],"domain_scores_gemma":[0.99956447,0.000007300654,0.00004594181,0.00030423573,0.00003767669,0.000040364466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014002,0.00015687839,0.00017198118,0.00008765687,0.000051371095,0.0000060919583,0.00024942553,0.0004700701,0.000009923337],"category_scores_gemma":[0.0000831877,0.00017024718,0.000060674687,0.00017543451,0.00031671245,0.000002361406,0.00012890885,0.00010220743,0.0000023299365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004074617,0.000050618415,0.00080488616,0.000023490526,0.000055656255,0.0000023530447,0.00011368559,0.00006803283,0.85056853,0.034838874,0.0003226925,0.113110445],"study_design_scores_gemma":[0.0013797348,0.001117311,0.011131183,0.000022385178,0.000019339212,0.000037990478,0.0002990925,0.0003803223,0.57875824,0.0014124145,0.40495378,0.00048817214],"about_ca_topic_score_codex":0.000010044036,"about_ca_topic_score_gemma":0.00027548362,"teacher_disagreement_score":0.4046311,"about_ca_system_score_codex":0.00003159762,"about_ca_system_score_gemma":0.000013226463,"threshold_uncertainty_score":0.69424784},"labels":[],"label_agreement":null},{"id":"W2806478486","doi":"10.1186/s13059-018-1443-z","title":"Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion","year":2018,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":496,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Key Research and Development Program of China; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Biology; CRISPR; Cytosine; Genome editing; Cas9; Point mutation; Thymine; Adenosine deaminase; Gene; Genetics; Cytosine deaminase; Rice plant; Base (topology); Computational biology; Base pair; Adenosine; Mutation; Biochemistry; DNA; Agronomy; Genetic enhancement","score_opus":0.012845773106475104,"score_gpt":0.3130833730037014,"score_spread":0.3002375998972263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806478486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894156,0.0024882653,0.007544208,0.00004972799,0.00020734314,0.0001081613,0.000011987555,0.000009599265,0.0001651468],"genre_scores_gemma":[0.99647933,0.00015140363,0.00229451,0.00011945622,0.0008309318,0.0000065913187,0.000053370768,0.000015703306,0.000048704493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991406,0.00004029962,0.00016702143,0.00033254738,0.000030766474,0.0002887332],"domain_scores_gemma":[0.9996636,0.0000097577,0.000034187342,0.00018302603,0.000039295566,0.00007012822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015422425,0.00013280458,0.00013681581,0.00008011092,0.00006861093,0.000009247851,0.00007962442,0.00015797811,0.000020880667],"category_scores_gemma":[0.000051287432,0.00013050964,0.000024650752,0.00008952028,0.00009853111,0.000002245387,0.00014933258,0.00006363201,0.000004298244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002993459,0.000014630694,0.0048550824,0.000014119841,0.0000074958557,0.000006092531,0.00010561831,0.000027984372,0.99354744,0.00000824651,0.000021320402,0.0013620482],"study_design_scores_gemma":[0.0020956963,0.0012225999,0.04476514,0.000044115422,0.000036310477,0.00035801492,0.00046443945,0.0023490207,0.9310974,0.000115688694,0.01676905,0.00068254664],"about_ca_topic_score_codex":0.000090180954,"about_ca_topic_score_gemma":0.00012323055,"teacher_disagreement_score":0.06245005,"about_ca_system_score_codex":0.000016392027,"about_ca_system_score_gemma":0.000022946318,"threshold_uncertainty_score":0.53220284},"labels":[],"label_agreement":null},{"id":"W2806892099","doi":"10.1128/aem.00991-18","title":"Substrate-Specific Differential Gene Expression and RNA Editing in the Brown Rot Fungus Fomitopsis pinicola","year":2018,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Science Foundation","keywords":"Gene; Gene expression; Fungus; Biology; RNA; Transcription (linguistics); Botany; Genetics","score_opus":0.004924796541416591,"score_gpt":0.20641652644925756,"score_spread":0.20149172990784098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806892099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976389,0.0010667582,0.00077542366,0.00002943205,0.00011158319,0.00014719756,0.000024281573,0.000004045456,0.0002024119],"genre_scores_gemma":[0.998345,0.00057946384,0.00030895628,0.000110772955,0.0004298546,0.000021336638,0.00017284349,0.000012101771,0.000019671634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929154,0.000024469919,0.00013771752,0.0003115337,0.000023789138,0.00021095423],"domain_scores_gemma":[0.9997715,0.000011558454,0.000030119054,0.00015183662,0.000001330549,0.000033685614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006865356,0.00013834368,0.00010864992,0.000020289022,0.000093214294,0.00001551422,0.00009360392,0.00013461342,0.00003090121],"category_scores_gemma":[0.0000013966602,0.00010786954,0.000021788816,0.00001868768,0.00021184405,0.0000017483469,0.0001273556,0.00008570073,0.000004784663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003130251,0.000027201317,0.0015731788,0.0000038298936,0.000007561793,0.0000010156283,0.00014299569,0.000004582004,0.9960725,0.000012299952,0.00022462916,0.0018989275],"study_design_scores_gemma":[0.00064200984,0.00013386123,0.024631837,0.0000045412376,0.000007214248,0.00005426596,0.00041491073,0.000009787515,0.96642697,0.000021005695,0.007501608,0.00015198057],"about_ca_topic_score_codex":0.0000034293087,"about_ca_topic_score_gemma":0.000008398163,"teacher_disagreement_score":0.029645499,"about_ca_system_score_codex":0.0000060147613,"about_ca_system_score_gemma":0.000002292655,"threshold_uncertainty_score":0.4398792},"labels":[],"label_agreement":null},{"id":"W2807348997","doi":"10.1101/344234","title":"Complete Disruption of Autism-Susceptibility Genes by Gene-Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; University of Prince Edward Island; SickKids Foundation; University of Toronto; McMaster University; Hospital for Sick Children","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Ontario Genomics; National Institutes of Health; Hospital for Sick Children; Sick Kids Foundation; Genome Canada; Canadian Institute for Advanced Research; Autism Speaks; University of Toronto; National Alliance for Research on Schizophrenia and Depression; GlaxoSmithKline; International Rett Syndrome Foundation","keywords":"Biology; Gene; Induced pluripotent stem cell; Candidate gene; CRISPR; Phenotype; Genetics; Excitatory postsynaptic potential; Neuroscience; Receptor","score_opus":0.015034137530293642,"score_gpt":0.26017497947014334,"score_spread":0.2451408419398497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807348997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98230785,0.001804232,0.013172952,0.000026989968,0.0008344731,0.00044584123,0.0013553534,0.000047636582,0.0000046686478],"genre_scores_gemma":[0.9974278,0.00017238494,0.0016659092,0.000012119861,0.00056180026,0.00005983906,0.000016789336,0.00007856378,0.0000047590665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99753386,0.00014581338,0.0006840707,0.0009715256,0.00028819733,0.00037651826],"domain_scores_gemma":[0.99783516,0.000029048582,0.0005724567,0.0010289031,0.00039680247,0.00013760738],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005135479,0.00044187673,0.00053971325,0.00010709574,0.00013562507,0.00003070838,0.00037861752,0.0004670769,0.000030440397],"category_scores_gemma":[0.00016088887,0.0005101145,0.00026086016,0.00015502032,0.0003407263,0.000009223908,0.0005133991,0.00027028035,0.0000025252898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004706733,0.00014957246,0.009435962,0.0003171193,0.00016714323,0.0000011598686,0.000005586764,0.0004168555,0.9891305,0.000026107971,0.00029834916,0.000004556985],"study_design_scores_gemma":[0.00036438607,0.00020077419,0.14648588,0.000089029825,0.00010197833,6.00659e-8,0.0000030970682,0.00029520926,0.85157377,0.0000020741027,0.000518849,0.00036486992],"about_ca_topic_score_codex":0.00005542538,"about_ca_topic_score_gemma":0.000011112111,"teacher_disagreement_score":0.13755673,"about_ca_system_score_codex":0.000052020725,"about_ca_system_score_gemma":0.00020414375,"threshold_uncertainty_score":0.99973506},"labels":[],"label_agreement":null},{"id":"W2807389226","doi":"10.3390/mps1020017","title":"A Two-Step Method for Obtaining Highly Pure Cas9 Nuclease for Genome Editing, Biophysical, and Structural Studies","year":2018,"lang":"en","type":"article","venue":"Methods and Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada)","funders":"","keywords":"Cas9; Genome editing; Ribonucleoprotein; Computational biology; CRISPR; Nuclease; RNA; DNA; Genome; Biology; Gene; Biochemistry","score_opus":0.039541532462902054,"score_gpt":0.4908049222223368,"score_spread":0.45126338975943475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807389226","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03885582,0.0006999865,0.9361007,0.00016305325,0.00012457823,0.023902792,0.00007568752,0.000022429254,0.00005493177],"genre_scores_gemma":[0.012642896,0.000012328319,0.9573606,0.00012340295,0.0015472404,0.028098611,0.00001627719,0.000034881337,0.00016373738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990207,0.000091702634,0.0001880221,0.00039142586,0.000046977093,0.00026118496],"domain_scores_gemma":[0.9993989,0.00011568648,0.00007055723,0.00018036958,0.00014615276,0.00008834138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070753344,0.0001840381,0.00025918565,0.000028672817,0.0002135641,0.000051294002,0.00008067459,0.000085571264,0.0000034806103],"category_scores_gemma":[0.00029036353,0.00015343574,0.00006999407,0.000044118595,0.00010706921,0.000004589874,0.00010767599,0.000051436982,1.4950342e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018432876,0.000008459423,0.00004931019,0.00033792196,0.000118335265,3.34463e-7,0.0003129409,0.00001497463,0.92546487,0.0005940646,0.00037925143,0.072535194],"study_design_scores_gemma":[0.0028136827,0.002852418,0.0002861685,0.000077977435,0.000108644264,0.00003145667,0.00064315327,0.013862804,0.5983075,0.0031534403,0.3773468,0.00051595474],"about_ca_topic_score_codex":0.0000049424857,"about_ca_topic_score_gemma":0.0000061418245,"teacher_disagreement_score":0.37696758,"about_ca_system_score_codex":0.0000055241203,"about_ca_system_score_gemma":0.000018268644,"threshold_uncertainty_score":0.6256928},"labels":[],"label_agreement":null},{"id":"W2807520101","doi":"10.1016/j.jogc.2018.04.019","title":"La spirale en ciment","year":2018,"lang":"en","type":"editorial","venue":"Journal of Obstetrics and Gynaecology Canada","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine","score_opus":0.0033743496117755838,"score_gpt":0.2479810718256799,"score_spread":0.24460672221390434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807520101","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02386556,0.014783429,0.0001733217,0.000033604352,0.9600769,0.000061109524,0.00006177797,0.000001392766,0.00094287464],"genre_scores_gemma":[0.47897315,0.0064910618,0.001516354,0.00021914518,0.509891,0.000007925331,0.00017495257,0.0001250622,0.0026013695],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988429,0.00006616778,0.00037474293,0.00018813749,0.0003111882,0.00021684957],"domain_scores_gemma":[0.9982628,0.00081298174,0.00028375405,0.00016695842,0.00032470012,0.00014880957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033510439,0.00019105684,0.00032105847,0.000107370695,0.000041747262,0.000021856895,0.00024207444,0.0007068254,0.000049795253],"category_scores_gemma":[0.0040309085,0.00017557396,0.00007735962,0.00007697803,0.000053616644,0.0000017586508,0.00011333704,0.00047384825,4.248046e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000031449574,0.000016777392,0.00030892063,0.000042955104,0.00015144935,0.00028612648,0.000013037851,0.000038665905,0.00020773278,0.000002240371,0.9891506,0.009778392],"study_design_scores_gemma":[0.00066673395,0.0005006863,0.0014272151,0.000006498326,0.000072511546,0.000020273332,0.00003377604,0.000004380795,0.0007478949,0.000008037157,0.996335,0.00017697387],"about_ca_topic_score_codex":0.0015748268,"about_ca_topic_score_gemma":0.009581815,"teacher_disagreement_score":0.4551076,"about_ca_system_score_codex":0.00024217524,"about_ca_system_score_gemma":0.0021213812,"threshold_uncertainty_score":0.71596986},"labels":[],"label_agreement":null},{"id":"W2807624799","doi":"10.1038/nbt.4166","title":"Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos","year":2018,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":347,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"CRISPR; Biology; Homologous recombination; Genome editing; Gene targeting; Transgenesis; Gene knockin; Genetics; Chromatin; Cas9; Embryo; Computational biology; Gene; Cell biology; Embryogenesis; Reproductive technology","score_opus":0.0032983053571978096,"score_gpt":0.2674415670147394,"score_spread":0.2641432616575416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807624799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94161993,0.0024370763,0.055045158,0.00020860415,0.0003342722,0.00015568505,0.000057587626,0.000054810196,0.00008685188],"genre_scores_gemma":[0.9957168,0.000078587356,0.002906515,0.00012505776,0.00018457675,0.000010271911,0.00023342989,0.000021425754,0.0007233228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991708,0.000021031676,0.00018456297,0.00033042568,0.00007820364,0.00021500002],"domain_scores_gemma":[0.99941313,0.0000030602753,0.00007148677,0.00037179582,0.000106351734,0.000034171444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095651965,0.00013905574,0.000118961514,0.00012319392,0.00009174777,0.0000063043085,0.000157221,0.0008869574,0.000019475248],"category_scores_gemma":[0.00006171639,0.00014107552,0.000055888664,0.00020562005,0.0001017773,0.0000012791246,0.0000948732,0.0002703292,0.000008402749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020518733,0.00009264134,0.00009099358,0.000011233404,0.000018601697,3.479027e-7,0.000027088521,0.00026103825,0.9946691,0.00017479216,0.0043132366,0.00032040934],"study_design_scores_gemma":[0.0004936097,0.00029590167,0.000053353648,0.000002817863,0.000010433508,0.000004079443,0.000036924313,0.0033731707,0.9665615,0.0000044427848,0.02902548,0.00013826852],"about_ca_topic_score_codex":0.000024074987,"about_ca_topic_score_gemma":0.000120287594,"teacher_disagreement_score":0.05409686,"about_ca_system_score_codex":0.000019972344,"about_ca_system_score_gemma":0.000028388864,"threshold_uncertainty_score":0.6841028},"labels":[],"label_agreement":null},{"id":"W2807817820","doi":"10.1093/nar/gky674","title":"Optimized knock-in of point mutations in zebrafish using CRISPR/Cas9","year":2018,"lang":"en","type":"erratum","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Appili Therapeutics (Canada); McMaster University; Dalhousie University","funders":"","keywords":"CRISPR; Biology; Cas9; Zebrafish; Gene knockin; Point mutation; Genetics; Computational biology; Genome editing; Palindrome; Mutation; Polymerase chain reaction; Gene","score_opus":0.03605644548208621,"score_gpt":0.3946273896439861,"score_spread":0.3585709441618999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807817820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8688335,0.013518502,0.014085809,0.00073693035,0.009658159,0.0032338835,0.00038782752,0.00006579,0.089479595],"genre_scores_gemma":[0.9234684,0.0026051106,0.023464821,0.00008970991,0.0033286002,0.00016771269,0.001364491,0.00040414307,0.04510699],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99743557,0.00023087273,0.000531024,0.0006091376,0.0005119952,0.0006813917],"domain_scores_gemma":[0.99871206,0.000045182616,0.00007921719,0.00069727394,0.00035258813,0.00011370343],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011113234,0.00025998827,0.0004387665,0.00067431515,0.000066933135,0.000038210583,0.00053591834,0.00076995644,0.00019949257],"category_scores_gemma":[0.00058709603,0.00028411808,0.00013949933,0.0006007668,0.000278734,0.000005338816,0.0004366391,0.0009899761,0.00001703302],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043448483,0.00046769556,0.00090976927,0.0008903406,0.00018303642,0.00011332467,0.0010463375,0.008120481,0.4248185,0.00004402035,0.5608894,0.0020825916],"study_design_scores_gemma":[0.009132821,0.0024256133,0.009268014,0.002860739,0.00011313278,0.00012366264,0.003235109,0.07301232,0.3510574,0.000938881,0.5450174,0.0028148724],"about_ca_topic_score_codex":0.0003580432,"about_ca_topic_score_gemma":0.00025716636,"teacher_disagreement_score":0.07376109,"about_ca_system_score_codex":0.00011216303,"about_ca_system_score_gemma":0.00048274783,"threshold_uncertainty_score":0.9999611},"labels":[],"label_agreement":null},{"id":"W2808410617","doi":"10.3390/ijms19072041","title":"Recent Developments in Using Drosophila as a Model for Human Genetic Disease","year":2018,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Drosophila (subgenus); Human disease; Disease; Biology; Value (mathematics); Candidate gene; Computational biology; Genetics; Gene; Evolutionary biology; Data science; Computer science; Medicine; Machine learning; Pathology","score_opus":0.0636766851535785,"score_gpt":0.4354154601298287,"score_spread":0.3717387749762502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808410617","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012288096,0.9608475,0.026075432,0.000024954885,0.0004959317,0.00020189889,0.000015535785,0.0000015163336,0.000049129652],"genre_scores_gemma":[0.010750741,0.97510695,0.013649656,0.00007920246,0.00031789806,0.000012504413,0.000021460508,0.000024267305,0.00003733495],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99854714,0.00003498858,0.0005618566,0.0002695121,0.00040752513,0.00017900643],"domain_scores_gemma":[0.9991654,0.00000909611,0.0003368125,0.00010970181,0.0002773915,0.00010157495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035743325,0.00018639615,0.00030343165,0.00028107947,0.000046922913,0.000065654305,0.0007944503,0.00009404951,0.0000035272285],"category_scores_gemma":[0.00012905964,0.00016215662,0.0002537095,0.00011270505,0.00009291329,0.0000059873237,0.0001321867,0.00008414912,0.0000010466383],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001165802,0.000485821,0.00013023133,0.0013838487,0.0010055158,0.00043973135,0.00018714964,0.07687133,0.020156058,0.000505398,0.00025307556,0.8984653],"study_design_scores_gemma":[0.0013014491,0.00057387276,0.00006672116,0.008156065,0.00044140202,0.0007034589,0.000026944828,0.014009894,0.0031764067,0.0029262686,0.9674997,0.0011178467],"about_ca_topic_score_codex":0.0000017950831,"about_ca_topic_score_gemma":0.0000034228221,"teacher_disagreement_score":0.9672466,"about_ca_system_score_codex":0.00006754711,"about_ca_system_score_gemma":0.0008733386,"threshold_uncertainty_score":0.6612555},"labels":[],"label_agreement":null},{"id":"W2808872711","doi":"10.1101/350504","title":"Potent Cas9 inhibition in bacterial and human cells by new anti-CRISPR protein families","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Cas9; Biology; Haemophilus parainfluenzae; Genome editing; Genome; Computational biology; Acquired immune system; Gene; Mobile genetic elements; Genetics; Bacteria; Immune system; Haemophilus","score_opus":0.0063564978126104885,"score_gpt":0.23010625854059888,"score_spread":0.22374976072798838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808872711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99525094,0.0010022814,0.00228125,0.000052805724,0.00050126354,0.0006818186,0.00016722908,0.000055232205,0.00000718924],"genre_scores_gemma":[0.9970243,0.00031958643,0.0015658623,0.00004746599,0.00084675464,0.00007565857,0.000006377014,0.000093801355,0.000020181094],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803215,0.00006336857,0.00041160476,0.0008946388,0.00016877576,0.00042946506],"domain_scores_gemma":[0.99885917,0.000004020745,0.00015281417,0.00066343317,0.000114599716,0.00020595055],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023500875,0.00046138497,0.00036960698,0.00014216495,0.00008119865,0.00013107352,0.00017347226,0.000598484,0.00001627713],"category_scores_gemma":[0.000037551396,0.00053271255,0.00008027271,0.000121506346,0.00010356715,0.000007952149,0.0004664354,0.0003155343,0.000008356399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002089154,0.000057883393,0.0007952101,0.00017423209,0.000037571775,0.000014044897,0.0000069858743,0.000040637562,0.9972227,0.0000103401635,0.0016166783,0.0000028037682],"study_design_scores_gemma":[0.0006605389,0.00012988491,0.011917982,0.00021982018,0.000027109414,3.9360003e-8,0.0000029471955,0.00002142787,0.9785011,0.0000012209333,0.007936006,0.0005819459],"about_ca_topic_score_codex":0.00023972504,"about_ca_topic_score_gemma":0.000024442705,"teacher_disagreement_score":0.018721644,"about_ca_system_score_codex":0.00005535354,"about_ca_system_score_gemma":0.0001869499,"threshold_uncertainty_score":0.99971247},"labels":[],"label_agreement":null},{"id":"W2808880569","doi":"10.1534/g3.118.200539","title":"A <i>Drosophila</i> CRISPR/Cas9 Toolkit for Conditionally Manipulating Gene Expression in the Prothoracic Gland as a Test Case for Polytene Tissues","year":2018,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Cas9; Biology; Polytene chromosome; Prothoracic gland; RNA interference; Gene; Computational biology; Gene expression; Regulation of gene expression; Phenotype; Genome editing; Cell biology; Genetics; Drosophila melanogaster; RNA","score_opus":0.020691067369757177,"score_gpt":0.3382022332804061,"score_spread":0.31751116591064893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808880569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.754523,0.16438103,0.07580749,0.00042639015,0.00042233942,0.0036605601,0.00048802374,0.00004273532,0.0002484604],"genre_scores_gemma":[0.9426986,0.003927725,0.048897907,0.0005238733,0.0021235284,0.0009484133,0.00046651624,0.00009376621,0.00031968867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998151,0.00004802771,0.00045109724,0.00061058596,0.00019171357,0.00054758927],"domain_scores_gemma":[0.9988331,0.00011704383,0.00013051323,0.0005836864,0.00023116625,0.000104478895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037587987,0.00033925968,0.00024975382,0.000086239794,0.00031518436,0.00009641839,0.00036671417,0.00021346279,0.000015469073],"category_scores_gemma":[0.00005680016,0.00029329074,0.00014916548,0.00014350598,0.000107465254,0.000006754222,0.00013286926,0.00007981361,0.000007851324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013615805,0.000104725645,0.00272426,0.0001349673,0.000041156578,0.000044167573,0.00044748397,0.0014306899,0.9421175,0.000026824047,0.0006649758,0.052127097],"study_design_scores_gemma":[0.0013346826,0.0014734468,0.00056947884,0.000033277684,0.00007363603,0.0011364779,0.00042474412,0.0024849128,0.8488398,0.00044948453,0.14264062,0.0005394492],"about_ca_topic_score_codex":0.0000108809545,"about_ca_topic_score_gemma":0.000120319695,"teacher_disagreement_score":0.1881756,"about_ca_system_score_codex":0.00002106044,"about_ca_system_score_gemma":0.00009512236,"threshold_uncertainty_score":0.9999519},"labels":[],"label_agreement":null},{"id":"W2809300200","doi":"10.1093/gbe/evy123","title":"Rates and Patterns of Mutation in Tandem Repetitive DNA in Six Independent Lineages of Chlamydomonas reinhardtii","year":2018,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Chlamydomonas reinhardtii; Chlamydomonas; Evolutionary biology; Genetics; Mutation; Tandem repeat; Mutation rate; DNA; Computational biology; Gene; Genome; Mutant","score_opus":0.005772779456475991,"score_gpt":0.27973665162736727,"score_spread":0.2739638721708913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809300200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943885,0.0018338087,0.0035662083,0.000020293242,0.000045627094,0.00008680603,0.000011916192,0.0000017282251,0.000045096258],"genre_scores_gemma":[0.9992839,0.00046219362,0.00010442286,0.0000073767974,0.000060358085,0.00000556307,0.000052821157,0.0000037660816,0.000019602809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994927,0.00003713634,0.00017960915,0.00017083311,0.000022521288,0.000097219825],"domain_scores_gemma":[0.99980694,0.000010417816,0.00005487703,0.00007157912,0.00003948867,0.000016695982],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017876933,0.00006492339,0.00011365564,0.000062626794,0.000013641964,0.0000013107754,0.000030577477,0.00013288826,0.000004299304],"category_scores_gemma":[0.000042775955,0.00006362054,0.000013532038,0.000047998426,0.00008993594,0.000002604152,0.000041620417,0.000040288705,2.7259514e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032816963,0.000012682043,0.42240375,0.000013886929,0.000007996357,5.489096e-7,0.00012376353,0.0000260322,0.57688636,0.00007742517,7.455784e-7,0.00041400795],"study_design_scores_gemma":[0.0003866129,0.00031572068,0.8058746,0.000016989397,0.000004083643,0.0000063019925,0.00013182477,0.000088687746,0.19293304,0.00013141878,0.000054446904,0.00005626713],"about_ca_topic_score_codex":0.00010223623,"about_ca_topic_score_gemma":0.00054475456,"teacher_disagreement_score":0.3839533,"about_ca_system_score_codex":0.000008862405,"about_ca_system_score_gemma":0.000014418218,"threshold_uncertainty_score":0.25943702},"labels":[],"label_agreement":null},{"id":"W2809595124","doi":"10.1089/crispr.2017.0020","title":"TIE: A Method to Electroporate Long DNA Templates into Preimplantation Embryos for CRISPR-Cas9 Gene Editing","year":2018,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Electroporation; CRISPR; Genome editing; Cas9; Microinjection; Plasmid; Biology; Endonuclease; Oligonucleotide; DNA; Template; Computational biology; Gene; Molecular biology; Cell biology; Genetics; Computer science","score_opus":0.01210721544504288,"score_gpt":0.3676910347957183,"score_spread":0.3555838193506754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809595124","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.281248,0.0004920714,0.71673036,0.00077396,0.00041894676,0.00023747259,0.000008216081,0.000014124059,0.00007683468],"genre_scores_gemma":[0.9375656,0.000096419375,0.055905372,0.0007860213,0.005218313,0.000042592827,0.00003785029,0.000056510435,0.00029132562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876004,0.00009219334,0.0003147569,0.0002575527,0.00015576284,0.00041969298],"domain_scores_gemma":[0.99914914,0.000042175896,0.0001275602,0.00024580842,0.00028431288,0.00015102417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009107586,0.0001916863,0.00016143337,0.000072926676,0.0004504205,0.000116426905,0.00029213564,0.0001004224,0.000023783392],"category_scores_gemma":[0.00015830359,0.00014632814,0.00011028153,0.000118586824,0.000039089435,0.000009318168,0.000079856676,0.00017644884,0.000013600372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015739986,0.000013937063,0.00011075599,0.000020207723,0.00008938331,0.0000041287817,0.00045922413,0.00048737798,0.9729153,0.000018787336,0.016125139,0.009598347],"study_design_scores_gemma":[0.00043563562,0.00061243324,0.00041524947,0.000021301385,0.0000690134,0.000654195,0.00026398033,0.000924962,0.974973,0.00049044087,0.020939881,0.00019989905],"about_ca_topic_score_codex":0.0000140311795,"about_ca_topic_score_gemma":0.000044792356,"teacher_disagreement_score":0.660825,"about_ca_system_score_codex":0.000028525594,"about_ca_system_score_gemma":0.000055212517,"threshold_uncertainty_score":0.59670883},"labels":[],"label_agreement":null},{"id":"W2810487964","doi":"10.1016/j.ymthe.2018.06.002","title":"Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34+ Hematopoietic Stem and Progenitor Cells","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Stanford Maternal and Child Health Research Institute; Amon G. Carter Foundation; Sundhed og Sygdom, Det Frie Forskningsråd; Children's Health Research Institute; National Heart, Lung, and Blood Institute; Natur og Univers, Det Frie Forskningsråd; National Institute of Allergy and Infectious Diseases; Stanford University","keywords":"Genome editing; Biology; Stem cell; Cas9; Cell biology; Haematopoiesis; RNA editing; Progenitor cell; Electroporation; CRISPR; Gene expression; Genetics; Gene","score_opus":0.0077512330091821895,"score_gpt":0.2819906133048418,"score_spread":0.27423938029565964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810487964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9293306,0.001852131,0.067854986,0.00034095137,0.00017715375,0.00034375684,0.000027218946,0.000019096882,0.000054092292],"genre_scores_gemma":[0.99627745,0.000025634106,0.00252967,0.0007786883,0.00023633227,0.0000533154,0.000015166802,0.000031571377,0.000052194875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878895,0.0000972671,0.00020876521,0.00041449955,0.00016653143,0.00032400322],"domain_scores_gemma":[0.9994805,0.00000848973,0.000027934104,0.00028056075,0.00006664983,0.00013587077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002677496,0.00020270525,0.00015252431,0.000066377324,0.00005621422,0.00003758207,0.00015580728,0.00012482767,0.000017557728],"category_scores_gemma":[0.0000125587485,0.00021271252,0.00007597369,0.00017187276,0.00006300153,0.0000028293823,0.00003270069,0.000057722133,0.000011091289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005889336,0.00004807776,0.0005614894,0.000013474425,0.000024091813,0.000021525106,0.00014698632,0.00058590405,0.9965438,0.00001845071,0.000046807912,0.0014004553],"study_design_scores_gemma":[0.0012055662,0.00063829275,0.005267689,0.000020211537,0.0000067005867,0.00002206487,0.000082958606,0.00021929343,0.971804,0.000026499838,0.020433478,0.00027321937],"about_ca_topic_score_codex":0.000009970053,"about_ca_topic_score_gemma":0.000019838686,"teacher_disagreement_score":0.06694681,"about_ca_system_score_codex":0.000029053639,"about_ca_system_score_gemma":0.00006082629,"threshold_uncertainty_score":0.8674165},"labels":[],"label_agreement":null},{"id":"W2810682161","doi":"10.1111/pbi.12982","title":"Activities and specificities of <scp>CRISPR</scp>/Cas9 and Cas12a nucleases for targeted mutagenesis in maize","year":2018,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Food and Agriculture; National Cancer Institute; Iowa State University; National Institutes of Health; University of Maryland; U.S. Department of Agriculture","keywords":"CRISPR; Biology; Genome editing; Cas9; Genetics; Guide RNA; Indel; Computational biology; Mutagenesis; Genome; Transcription activator-like effector nuclease; Trans-activating crRNA; Gene; Nuclease; RNA; Mutation","score_opus":0.007814371272212019,"score_gpt":0.2504014910939184,"score_spread":0.2425871198217064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810682161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898288,0.0055753877,0.004075424,0.00011439643,0.00012925145,0.00009865894,0.000113267575,0.0000119663455,0.000052813506],"genre_scores_gemma":[0.99301934,0.0039620018,0.0027264382,0.000027611904,0.00015893874,0.0000049448277,0.000011630343,0.000015815383,0.00007329574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929976,0.000016133348,0.00020238169,0.00018841775,0.00005203801,0.00024124603],"domain_scores_gemma":[0.9996734,0.00005139859,0.000080705955,0.00011539043,0.000031425847,0.000047665548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013554667,0.00013186905,0.00019229576,0.0001857017,0.00008110265,0.000018281311,0.000098712044,0.00027259925,0.0000042704896],"category_scores_gemma":[0.0001382788,0.00012379709,0.000034890727,0.00005912862,0.00029517585,0.000004933056,0.0000740181,0.00012407877,2.9289765e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055349967,0.000024269117,0.002851919,0.000041374824,0.000057658784,0.000013261788,0.00014978029,0.000010531785,0.9919256,0.0001483782,0.00080783723,0.00391407],"study_design_scores_gemma":[0.0005451516,0.0005090504,0.0035840974,0.00003102242,0.000020218,0.0008542414,0.0016301032,0.00015817884,0.97690785,0.00017641379,0.015510063,0.000073601164],"about_ca_topic_score_codex":0.0000120013865,"about_ca_topic_score_gemma":0.00007209544,"teacher_disagreement_score":0.01501771,"about_ca_system_score_codex":0.0000069247158,"about_ca_system_score_gemma":0.000023343564,"threshold_uncertainty_score":0.5048299},"labels":[],"label_agreement":null},{"id":"W2811024324","doi":"10.1016/j.ddtec.2018.06.002","title":"CRISPR/Cas9-mediated genome editing in human stem cell-derived cardiomyocytes: Applications for cardiovascular disease modelling and cardiotoxicity screening","year":2018,"lang":"en","type":"review","venue":"Drug Discovery Today Technologies","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Cardiotoxicity; CRISPR; Genome editing; Induced pluripotent stem cell; Cas9; Disease; Drug discovery; Medicine; Computational biology; Drug; Pharmacology; Biology; Bioinformatics; Embryonic stem cell; Genetics; Internal medicine; Gene; Chemotherapy","score_opus":0.023466293153392135,"score_gpt":0.2925402826558438,"score_spread":0.26907398950245165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2811024324","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011060733,0.71612793,0.28032804,0.000007940766,0.00006750165,0.001686712,0.0004943749,0.00015555599,0.000025877333],"genre_scores_gemma":[0.031030212,0.9626062,0.0022684673,0.0000055791925,0.0004230017,0.0023041042,0.0011432639,0.0001331627,0.0000860261],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99726593,0.00007417552,0.0006228035,0.0012243936,0.00022116423,0.00059153506],"domain_scores_gemma":[0.99831206,0.000067278845,0.0002018649,0.0012480483,0.000082127255,0.00008860193],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004558489,0.0006530607,0.0013760643,0.0003039386,0.00024506066,0.00013381007,0.00058042357,0.00054591993,3.239355e-7],"category_scores_gemma":[0.000054303448,0.00063590053,0.0011311221,0.0002957519,0.00023047882,0.00002043348,0.0005863813,0.00034708699,0.0000012891652],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119686454,0.0003762936,0.0002445453,0.074718036,0.009863157,0.000112737966,0.00041484676,0.21476427,0.011070905,0.00027052636,0.0010009266,0.6870441],"study_design_scores_gemma":[0.0005623605,0.0000666115,0.0000047861176,0.0017545493,0.0014761345,0.000011734174,0.00089597504,0.0008700315,0.005433067,0.00007830322,0.987549,0.0012974271],"about_ca_topic_score_codex":0.000026885009,"about_ca_topic_score_gemma":0.0000061678115,"teacher_disagreement_score":0.98654807,"about_ca_system_score_codex":0.00007166266,"about_ca_system_score_gemma":0.000101819256,"threshold_uncertainty_score":0.99960923},"labels":[],"label_agreement":null},{"id":"W2811426600","doi":"10.1101/359588","title":"Optimizing guide RNA selection and CRISPR/Cas9 methodology for efficient generation of deletions in <i>C. elegans</i>","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"CRISPR; Biology; Cas9; Genetics; ORFS; Computational biology; Caenorhabditis elegans; Gene; Genome; Genome editing; Open reading frame","score_opus":0.027693213554401193,"score_gpt":0.3024255481002651,"score_spread":0.27473233454586393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2811426600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59511185,0.0013884641,0.40258244,0.000037220907,0.00038564828,0.0004137956,0.00005587117,0.000021690717,0.000003012422],"genre_scores_gemma":[0.8499997,0.00033671057,0.14884071,0.000049108567,0.0005334622,0.0001731824,0.0000026104938,0.00006053115,0.0000039611987],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982469,0.0001183356,0.00049302954,0.00070185825,0.000110255074,0.0003295956],"domain_scores_gemma":[0.99882084,0.00003713407,0.00020750011,0.00043791198,0.00040660214,0.000090020854],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00081920286,0.00030121586,0.00036454614,0.00020357422,0.000077046054,0.000036605106,0.00017196732,0.00049586437,0.0000035758806],"category_scores_gemma":[0.00032711448,0.00035434368,0.000101165606,0.00017397579,0.00006899018,0.0000039370607,0.00019610503,0.0001977006,6.3306777e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030346384,0.000045430894,0.00031903447,0.00018254263,0.00005919254,7.717955e-7,0.000011177912,0.02013037,0.97883356,0.00006858921,0.00031288102,0.0000061286282],"study_design_scores_gemma":[0.00044957834,0.00014402746,0.0018151823,0.00007348257,0.00006948525,6.236246e-8,0.0000033364909,0.01832844,0.9757542,9.788945e-7,0.0030235604,0.00033765586],"about_ca_topic_score_codex":0.000046886074,"about_ca_topic_score_gemma":0.000031821713,"teacher_disagreement_score":0.25488785,"about_ca_system_score_codex":0.00005824137,"about_ca_system_score_gemma":0.00020552198,"threshold_uncertainty_score":0.99989086},"labels":[],"label_agreement":null},{"id":"W2813550190","doi":"10.1016/j.bej.2018.07.008","title":"Perspective: Solidifying the impact of cell-free synthetic biology through lyophilization","year":2018,"lang":"en","type":"article","venue":"Biochemical Engineering Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Connaught Fund; University of Toronto; Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation","keywords":"Synthetic biology; Biology; Artificial cell; Computational biology; Biochemical engineering; Cell-free protein synthesis; Biotechnology; Translation (biology); Computer science; Nanotechnology; Gene; Protein biosynthesis; Engineering; Biochemistry; Messenger RNA","score_opus":0.008145205584709526,"score_gpt":0.3154254646142477,"score_spread":0.30728025902953815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2813550190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8084658,0.0030806554,0.18767376,0.00008306483,0.00026168805,0.00007914698,0.000010617784,0.000015958534,0.00032934605],"genre_scores_gemma":[0.9952077,0.0002708855,0.0034770626,0.0000134753855,0.00097386946,0.000003074755,0.0000061872356,0.000027025153,0.00002070523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999212,0.000019084107,0.00022495577,0.00018375997,0.0000920722,0.00026810265],"domain_scores_gemma":[0.9993111,0.000021183809,0.00007501938,0.00034117544,0.000178343,0.00007317833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015392876,0.00016446468,0.00014079316,0.000042431297,0.00007129761,0.000020047219,0.00035302757,0.000116198345,0.00003129749],"category_scores_gemma":[0.00033800857,0.000116595096,0.00018733303,0.00012859995,0.00010984846,0.0000042595125,0.0001189665,0.00017110597,0.0000024249327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022435423,0.00002631143,0.000105550695,0.000010513889,0.000059259764,6.885473e-7,0.00011978103,0.0032700503,0.9951539,0.00011823772,0.0010584947,0.00005479817],"study_design_scores_gemma":[0.00041067557,0.00034695654,0.00048456233,0.00002864717,0.000023132929,0.00017947759,0.000070921,0.004268331,0.9929985,0.00026456686,0.0007474828,0.00017678685],"about_ca_topic_score_codex":0.000014258761,"about_ca_topic_score_gemma":2.3397452e-7,"teacher_disagreement_score":0.18674195,"about_ca_system_score_codex":0.00004737115,"about_ca_system_score_gemma":0.00005727106,"threshold_uncertainty_score":0.475461},"labels":[],"label_agreement":null},{"id":"W2818473048","doi":"10.1016/j.ccell.2018.05.014","title":"Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation","year":2018,"lang":"en","type":"article","venue":"Cancer Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of California, San Francisco; National Institutes of Health; Sandler Foundation; National Cancer Institute; Melanoma Research Alliance","keywords":"Cancer research; CDKN2A; Melanoma; Allele; Biology; Cell biology; Medicine; Genetics; Gene","score_opus":0.010506942074531275,"score_gpt":0.28516826486894525,"score_spread":0.27466132279441396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2818473048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850631,0.0012126127,0.010808238,0.000038965103,0.00016905117,0.00007537649,0.0000072160524,0.000007789314,0.002617663],"genre_scores_gemma":[0.9984316,0.0004721483,0.00033447123,0.00009462484,0.00035963178,0.000010898544,0.00003241186,0.000014045859,0.00025012725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999555,0.000008945845,0.00010852399,0.00015573009,0.000057063942,0.00011472995],"domain_scores_gemma":[0.9996737,0.0000047335116,0.000044095686,0.0001716551,0.00007120342,0.000034577006],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037795748,0.00007984884,0.00007463743,0.000017539802,0.000025570274,0.0000043963655,0.00008531355,0.0000782501,0.00011010743],"category_scores_gemma":[0.000008143283,0.00007773363,0.00003415254,0.000048828304,0.000043401138,0.0000027273252,0.00004407148,0.000029146866,0.000006870678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023927138,0.00001811103,0.0020665643,0.0000345092,0.000012036543,2.8273888e-7,0.00007323492,0.000073321986,0.99396217,0.0000069141984,0.00067296065,0.003055977],"study_design_scores_gemma":[0.0002447785,0.00017089228,0.0032064486,0.000016411748,0.0000078484445,0.0000012801524,0.000028936278,0.00009000087,0.98430675,0.00003624335,0.011795093,0.0000953228],"about_ca_topic_score_codex":0.00012149656,"about_ca_topic_score_gemma":0.000109989094,"teacher_disagreement_score":0.013368552,"about_ca_system_score_codex":0.00001277216,"about_ca_system_score_gemma":0.00004177882,"threshold_uncertainty_score":0.31698856},"labels":[],"label_agreement":null},{"id":"W2850515613","doi":"10.1039/c8lc00470f","title":"An automated microfluidic gene-editing platform for deciphering cancer genes","year":2018,"lang":"en","type":"article","venue":"Lab on a Chip","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Gene; Genome editing; Microfluidics; Computational biology; Biology; Computer science; Genetics; CRISPR; Nanotechnology; Materials science","score_opus":0.013786040643018062,"score_gpt":0.3335975781187325,"score_spread":0.3198115374757144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2850515613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867495,0.001753807,0.010520782,0.00003140451,0.00043064053,0.00016123144,0.000041484167,0.00010590727,0.00020525522],"genre_scores_gemma":[0.9942107,0.00020081412,0.0032775544,0.0002866775,0.001718627,0.000060608025,0.00008059176,0.00004271845,0.00012167012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922943,0.0000068854883,0.00013573916,0.00028588998,0.00006516864,0.0002768864],"domain_scores_gemma":[0.99956733,0.000007292252,0.000034477896,0.000249724,0.000060078248,0.00008111285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008858651,0.00014180996,0.000101241465,0.000027724336,0.00010745581,0.00002735648,0.00014490543,0.0001056548,0.000021370342],"category_scores_gemma":[0.000022230468,0.00013850704,0.00005187256,0.000054647742,0.000031177267,0.0000031634092,0.000031428066,0.00003859928,0.000006840968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000451321,0.000018130833,0.0006942297,0.00001796139,0.000028562068,6.8410856e-7,0.00007130859,0.0002421765,0.9878323,0.000017201502,0.0013258697,0.009706409],"study_design_scores_gemma":[0.00044348362,0.00032373032,0.0019769277,0.000018910087,0.000013246147,0.000006089911,0.000033883418,0.005001207,0.957654,0.0000114531485,0.034339525,0.00017751682],"about_ca_topic_score_codex":0.000023557826,"about_ca_topic_score_gemma":0.00006885679,"teacher_disagreement_score":0.033013657,"about_ca_system_score_codex":0.000014055101,"about_ca_system_score_gemma":0.00003002044,"threshold_uncertainty_score":0.5648153},"labels":[],"label_agreement":null},{"id":"W2883095167","doi":"10.1016/j.pbiomolbio.2018.07.005","title":"A beginner's guide to understanding and implementing the genetic modification of zebrafish","year":2018,"lang":"en","type":"review","venue":"Progress in Biophysics and Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"CRISPR; Zebrafish; Transcription activator-like effector nuclease; Genome editing; Biology; Computational biology; Forward genetics; Insertional mutagenesis; Genetic screen; Transgenesis; Cas9; Transposable element; Genetics; Gene; Genome; Phenotype","score_opus":0.030277267121411225,"score_gpt":0.4050247917181219,"score_spread":0.3747475245967107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883095167","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0045432923,0.968254,0.026350992,0.000058271424,0.00007769597,0.0006257338,0.000033763285,0.0000053383055,0.00005085714],"genre_scores_gemma":[0.04626062,0.94972914,0.0034601854,0.000050075407,0.00015678843,0.00016322463,0.00012531217,0.00004707302,0.0000075991184],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99865127,0.000088169654,0.0004043412,0.000490232,0.00005993846,0.00030608225],"domain_scores_gemma":[0.9993606,0.000019026167,0.00016716134,0.00036182447,0.000034118937,0.000057245325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023408006,0.00026590607,0.00046546143,0.00009949547,0.000059305454,0.000026106478,0.00021702194,0.00021087985,6.6834656e-7],"category_scores_gemma":[0.000022602957,0.00020425628,0.0001002871,0.00017465813,0.00023880131,0.0000013946373,0.0003835159,0.000094715644,4.4664998e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017088563,0.000058430807,0.00045334952,0.0033235722,0.00036478817,0.000005443481,0.00014219062,0.000006512661,0.016629362,0.009542968,0.00014030667,0.969316],"study_design_scores_gemma":[0.0005183671,0.00070520677,0.000106035004,0.0016628326,0.00040779644,0.0000536702,0.00011648984,0.00012715755,0.009355909,0.0019335594,0.98413,0.00088292547],"about_ca_topic_score_codex":0.000009899085,"about_ca_topic_score_gemma":0.000010268983,"teacher_disagreement_score":0.9839897,"about_ca_system_score_codex":0.000016391681,"about_ca_system_score_gemma":0.000046003428,"threshold_uncertainty_score":0.83293295},"labels":[],"label_agreement":null},{"id":"W2883634918","doi":"10.1101/378331","title":"CRISPR-induced deletion with SaCas9 restores dystrophin expression in dystrophic models <i>in vitro</i> and <i>in vivo</i>","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Dystrophin; Exon; Duchenne muscular dystrophy; Biology; Spectrin; Muscular dystrophy; Gene; CRISPR; Genetics; Molecular biology; Intron; Cytoskeleton","score_opus":0.009160815768576594,"score_gpt":0.23375016785709615,"score_spread":0.22458935208851954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883634918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926063,0.0018301,0.004519215,0.00004821644,0.00024855958,0.0006291353,0.000064709304,0.000044536177,0.000009271945],"genre_scores_gemma":[0.9931454,0.000520743,0.005624324,0.00007598073,0.00029382145,0.00021337568,0.0000013742863,0.00012265464,0.0000022985107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971834,0.00013164581,0.00055465766,0.0012462203,0.00027033524,0.00061376113],"domain_scores_gemma":[0.99856704,0.000016294915,0.00018675183,0.0009158563,0.00013634838,0.00017768165],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004354495,0.0005782293,0.0005328276,0.00037190193,0.00005198616,0.00008133373,0.00034431202,0.00072591286,0.0000036246465],"category_scores_gemma":[0.00005750976,0.0005939853,0.00006555393,0.00030263953,0.000095213974,0.000019763596,0.00039611978,0.0006211187,0.0000017375756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039115548,0.00008872754,0.0028776953,0.00019688075,0.000017993827,0.000079121346,0.00001241454,0.004076735,0.9922,0.0000069901785,0.000050311988,0.0000019640045],"study_design_scores_gemma":[0.0012346571,0.00014812149,0.015125976,0.0006354396,0.0000198255,1.7985063e-7,0.0000057168686,0.0023188808,0.9795302,0.0000037892976,0.00029140888,0.0006858029],"about_ca_topic_score_codex":0.00013290744,"about_ca_topic_score_gemma":0.000087986264,"teacher_disagreement_score":0.012669808,"about_ca_system_score_codex":0.00013228522,"about_ca_system_score_gemma":0.00023125853,"threshold_uncertainty_score":0.99965113},"labels":[],"label_agreement":null},{"id":"W2883957385","doi":"10.1242/dev.150888","title":"Gene editing in human development: ethical concerns and practical applications","year":2018,"lang":"en","type":"article","venue":"Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Genome editing; CRISPR; Human genetics; Induced pluripotent stem cell; Germline; Cas9; Computational biology; Gene; Human genome; Genetics; Engineering ethics; Genome; Embryonic stem cell","score_opus":0.021118895831518707,"score_gpt":0.3628747471693602,"score_spread":0.3417558513378415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883957385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9339745,0.00011854418,0.06408168,0.00023024231,0.000057311692,0.0001914184,8.571092e-7,0.000016305823,0.001329117],"genre_scores_gemma":[0.9573952,0.000011836065,0.041700754,0.0002370232,0.00037648118,0.00008460202,0.000049111157,0.00001176999,0.00013325372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992628,0.000013505921,0.00019700984,0.00024783323,0.00009109244,0.00018774797],"domain_scores_gemma":[0.99974495,0.000008448389,0.00002636638,0.00010604637,0.00004388057,0.000070320566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020872774,0.00009489845,0.000076131706,0.000034135428,0.00011732386,0.000016765409,0.000050649112,0.0001429026,0.000015931762],"category_scores_gemma":[0.000033237182,0.00010061791,0.000009072542,0.000056421766,0.00006331831,0.0000016106162,0.00011590208,0.00012637598,0.00001216139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040748702,0.00018685909,0.027758772,0.000102714504,0.00013122267,0.000021849732,0.0039975867,0.000038601847,0.8855596,0.0013263043,0.0036920002,0.07714372],"study_design_scores_gemma":[0.0003687665,0.000036017806,0.023684172,0.0000131969955,0.0000027033182,0.000018498005,0.00007369832,0.000022083004,0.7154783,0.00002232762,0.26010776,0.00017247528],"about_ca_topic_score_codex":0.0000023677119,"about_ca_topic_score_gemma":0.00007682429,"teacher_disagreement_score":0.25641575,"about_ca_system_score_codex":0.000020918496,"about_ca_system_score_gemma":0.00011366229,"threshold_uncertainty_score":0.4103079},"labels":[],"label_agreement":null},{"id":"W2883959588","doi":"10.1101/369249","title":"CRISPR-Cas9 human gene replacement and phenomic characterization in <i>Caenorhabditis elegans</i> to understand the functional conservation of human genes and decipher variants of uncertain significance","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Genetics; Gene; Caenorhabditis elegans; Computational biology; Genome; PTEN; CRISPR; Phenotype; Copy-number variation; PI3K/AKT/mTOR pathway","score_opus":0.01597465713098867,"score_gpt":0.25382233834693657,"score_spread":0.2378476812159479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883959588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9785562,0.00061213435,0.01987023,0.00007769582,0.00016280045,0.0005077913,0.0002012841,0.000009444706,0.0000024174044],"genre_scores_gemma":[0.99853575,0.00027123434,0.00080961233,0.00009545579,0.00018478799,0.000050337574,0.0000089771265,0.00003838275,0.0000054880106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986482,0.00006862303,0.00043121187,0.00052202295,0.00014456133,0.00018533552],"domain_scores_gemma":[0.9989837,0.000015467916,0.0002455741,0.00047641384,0.00020991628,0.000068942994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038300868,0.00023624062,0.00026606367,0.00009361679,0.00008509942,0.000036041634,0.00014288643,0.00019872445,0.000009812464],"category_scores_gemma":[0.00003422999,0.00023901869,0.000033414995,0.0001282547,0.0001348111,0.000007161217,0.00020584736,0.000108620574,2.9327808e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057547524,0.000037192473,0.014909117,0.00016749292,0.000064151514,0.000001121317,0.0000273901,0.00018342529,0.9843767,0.000113364906,0.000059605143,0.000002891763],"study_design_scores_gemma":[0.00035068215,0.00012557459,0.3549083,0.0000902362,0.0000321994,4.228436e-8,0.000013451662,0.00010727941,0.6439628,0.0000032117666,0.0002201679,0.00018604886],"about_ca_topic_score_codex":0.00009402784,"about_ca_topic_score_gemma":0.00003814163,"teacher_disagreement_score":0.34041387,"about_ca_system_score_codex":0.000046141588,"about_ca_system_score_gemma":0.00012042588,"threshold_uncertainty_score":0.9746899},"labels":[],"label_agreement":null},{"id":"W2884590356","doi":"10.1186/s12919-018-0109-x","title":"Public engagement pathways for emerging GM insect technologies","year":2018,"lang":"en","type":"review","venue":"BMC Proceedings","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Commonwealth Scientific and Industrial Research Organisation; North Carolina State University","keywords":"Public involvement; Public engagement; Context (archaeology); Agency (philosophy); Negotiation; Government (linguistics); Public relations; Gene drive; Public participation; Knowledge management; Control (management); Political science; Business; Sociology; Computer science; Biology; Management; Economics","score_opus":0.13286478773905974,"score_gpt":0.3562770639962261,"score_spread":0.22341227625716636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884590356","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010973647,0.9906904,0.006700989,0.000016491556,0.0002857359,0.0010147812,0.0000348579,0.00018414765,0.00096287025],"genre_scores_gemma":[0.0007605562,0.99062604,0.0065147597,0.000013387991,0.0006534091,0.0008951796,0.00015940901,0.00010161013,0.00027562294],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99833196,0.0000075997045,0.00039785184,0.00066393183,0.00012601572,0.00047266466],"domain_scores_gemma":[0.9992899,0.000017891787,0.00019378064,0.00026932152,0.0001715967,0.000057525864],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043041044,0.00042635755,0.0005868791,0.00018668461,0.0001403128,0.0000954452,0.0005484665,0.0004961012,0.000005464439],"category_scores_gemma":[0.00057780655,0.00037318232,0.0004004734,0.00020846854,0.000063153304,0.000004729609,0.00039805638,0.00019034884,0.000012318468],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009873317,0.0000513233,0.000024553774,0.029455846,0.00026141264,5.761946e-7,0.00006588341,4.850071e-7,0.0022207343,0.0012535185,0.019922901,0.9467329],"study_design_scores_gemma":[0.00014670232,0.00019488814,0.000001114992,0.0009914188,0.00014800903,0.000017224858,0.00010575622,0.000014149411,0.0027975165,0.00009416397,0.9950459,0.00044312765],"about_ca_topic_score_codex":7.2699396e-7,"about_ca_topic_score_gemma":0.000002411167,"teacher_disagreement_score":0.97512305,"about_ca_system_score_codex":0.000037583068,"about_ca_system_score_gemma":0.00015863903,"threshold_uncertainty_score":0.999872},"labels":[],"label_agreement":null},{"id":"W2884801482","doi":"10.3389/fgene.2018.00260","title":"CRISPR/Cas9 Application for Gene Copy Fate Survey of Polyploid Vertebrates","year":2018,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ontario Museum","funders":"National Postdoctoral Program for Innovative Talents; Yunnan Provincial Science and Technology Department; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"CRISPR; Polyploid; Biology; Genetics; Cas9; Gene; Epigenetics; Evolutionary biology; Genome; Computational biology","score_opus":0.02434590710774982,"score_gpt":0.35565112562286505,"score_spread":0.33130521851511524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884801482","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00020490999,0.74012375,0.25768653,0.0000015942551,0.0006742538,0.0008605869,0.00041209,0.0000071486315,0.000029138739],"genre_scores_gemma":[0.00041838273,0.9727027,0.023856921,0.000010971567,0.0003001968,0.00022793567,0.002163111,0.00010849188,0.00021131845],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981227,0.00009683698,0.00069064734,0.00059528294,0.00012896922,0.00036555267],"domain_scores_gemma":[0.9987141,0.00002849796,0.00027567238,0.00071650953,0.00018228932,0.000082929095],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038702544,0.00040097052,0.0009521225,0.00016683842,0.00003551947,0.000014824993,0.00048897957,0.00055417424,0.000003388494],"category_scores_gemma":[0.00010623877,0.00041078846,0.00025601196,0.00025443226,0.000104816,0.0000015109924,0.00012378726,0.000117580814,0.000003739754],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001235425,0.00019288156,0.0050070663,0.012213565,0.00077047624,0.0000010164435,0.00006330126,0.00039310483,0.0055926894,0.000006632678,0.0653171,0.9103186],"study_design_scores_gemma":[0.00038661167,0.00027714772,0.00027250964,0.00042655636,0.0002452202,0.0000043032965,0.000010075549,0.00075565855,0.029144801,0.000028680852,0.96789825,0.00055017276],"about_ca_topic_score_codex":0.000032904794,"about_ca_topic_score_gemma":0.000054712877,"teacher_disagreement_score":0.90976846,"about_ca_system_score_codex":0.00003687838,"about_ca_system_score_gemma":0.00021512421,"threshold_uncertainty_score":0.9998344},"labels":[],"label_agreement":null},{"id":"W2885552279","doi":"10.1128/jvi.01135-18","title":"HIV-1 Employs Multiple Mechanisms To Resist Cas9/Single Guide RNA Targeting the Viral Primer Binding Site","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Cas9; Biology; CRISPR; Subgenomic mRNA; Guide RNA; DNA; Reverse transcriptase; Genome editing; Primer (cosmetics); Virology; Human immunodeficiency virus (HIV); Genetics; RNA; Gene; Computational biology; Molecular biology; Chemistry","score_opus":0.00881762885325819,"score_gpt":0.28498574876633453,"score_spread":0.2761681199130763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885552279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8949494,0.0004978937,0.10279828,0.00077491126,0.0006466464,0.0000841735,0.000010181969,0.000006338124,0.00023217426],"genre_scores_gemma":[0.9845722,0.000025251118,0.012879571,0.00069632585,0.0012923913,0.000002590788,0.000008539136,0.000028386228,0.00049474975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989096,0.00007279003,0.00039662042,0.00018224868,0.00013223714,0.00030652527],"domain_scores_gemma":[0.99931186,0.00003497203,0.00017905208,0.00022418327,0.00014459249,0.00010536144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043897895,0.00014068336,0.00019079992,0.00008434661,0.00013427541,0.000023311579,0.0002758417,0.00012794812,0.000032065414],"category_scores_gemma":[0.00031539434,0.00010518379,0.0001176198,0.00007699334,0.00006804271,0.000004747252,0.00014937347,0.00015597839,0.000046042507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108033266,0.000025157939,0.0007823877,0.0000032488635,0.000052938347,0.000011858056,0.000120835735,0.0005246667,0.9846737,0.000012323479,0.0130665265,0.00061832415],"study_design_scores_gemma":[0.00046708903,0.0011708993,0.0016898162,0.000011393694,0.000039951177,0.00016061377,0.00007089358,0.00015270627,0.86855114,0.000038568527,0.12750469,0.00014224817],"about_ca_topic_score_codex":0.0000129152595,"about_ca_topic_score_gemma":0.000037810612,"teacher_disagreement_score":0.116122566,"about_ca_system_score_codex":0.000023033352,"about_ca_system_score_gemma":0.000035694393,"threshold_uncertainty_score":0.42892703},"labels":[],"label_agreement":null},{"id":"W2885626840","doi":"10.1101/389122","title":"Receptor Mediated Delivery of Cas9-Nanobody Induces Cisplatin Synthetic Dose Sensitivity","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; William Osler Health System","funders":"","keywords":"Ribonucleoprotein; Transfection; Cas9; CRISPR; Cisplatin; Chemistry; Cell biology; Internalization; A549 cell; Molecular biology; Cancer research; Cell; Biology; RNA; Gene; Biochemistry; Genetics","score_opus":0.009429592107996423,"score_gpt":0.24056059916442876,"score_spread":0.23113100705643233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885626840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944957,0.0014458498,0.0019300991,0.0000358803,0.0010954569,0.00042974,0.0004659787,0.00008628339,0.000014998481],"genre_scores_gemma":[0.9950146,0.0005615321,0.0035146957,0.000053509244,0.0006686221,0.000051161955,0.000005513736,0.00012437809,0.0000060017196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974714,0.00017416621,0.0005640906,0.0009808714,0.00031575965,0.00049370865],"domain_scores_gemma":[0.9974644,0.000060946455,0.00036939041,0.0013042488,0.00057320326,0.00022777084],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006648467,0.0005590268,0.00057149894,0.00017828478,0.00008249351,0.000049982107,0.000365343,0.0008648365,0.000043315733],"category_scores_gemma":[0.00043501737,0.0006147004,0.00020927332,0.00024070541,0.0002144177,0.000006749062,0.0006590062,0.0004080656,0.00003562871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057066325,0.00009207642,0.0011662337,0.00026110216,0.00020205147,0.000016208525,0.000008218125,0.00017868879,0.99757576,0.000009454295,0.00042793326,0.000005212065],"study_design_scores_gemma":[0.00036029425,0.00012839165,0.016867708,0.00027041067,0.00008875109,7.2924266e-8,0.0000037355069,0.00032747246,0.97878766,3.0761086e-7,0.0025124634,0.0006527151],"about_ca_topic_score_codex":0.00007037704,"about_ca_topic_score_gemma":0.000008771566,"teacher_disagreement_score":0.018788079,"about_ca_system_score_codex":0.000058416816,"about_ca_system_score_gemma":0.00043106166,"threshold_uncertainty_score":0.99963045},"labels":[],"label_agreement":null},{"id":"W2886012737","doi":"10.1158/1538-7445.am2018-390","title":"Abstract 390: Genome-wide CRISPR screens in brain tumor initiating cells (BTICs) identify potent sensitizers and resistors of conventional chemoradiotherapy","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"CRISPR; Temozolomide; Chemoradiotherapy; Cancer research; Medicine; Biology; Radiation therapy; Gene; Glioblastoma; Genetics; Internal medicine","score_opus":0.03223462503692623,"score_gpt":0.40212389956831507,"score_spread":0.36988927453138887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886012737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965294,0.0017024647,0.0008053491,0.000269818,0.00009020016,0.00018507881,0.000031735563,0.0000046119603,0.0003813504],"genre_scores_gemma":[0.9984364,0.0003807783,0.0005298635,0.00013998715,0.00027173944,0.000017301385,0.000018434457,0.000024750674,0.00018076577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988164,0.00006151503,0.00023499515,0.0003029209,0.0002537439,0.0003304811],"domain_scores_gemma":[0.9993754,0.0000624336,0.000047335834,0.00020502925,0.00021561582,0.00009418122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007324298,0.0001050925,0.00015406721,0.00014221235,0.00007193132,0.000021329372,0.00012733896,0.00007570571,0.00006598762],"category_scores_gemma":[0.00013189518,0.00011443299,0.000046785954,0.00015451695,0.0002751748,0.0000042482043,0.0000836729,0.0001694929,0.000002814215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094309704,0.00002157913,0.0038207672,0.00009292576,0.000030423824,0.000011221552,0.0001490418,0.00019450371,0.9937334,0.000008369864,0.0013290696,0.00051439786],"study_design_scores_gemma":[0.00068511115,0.000130594,0.09949906,0.00006723607,0.000003562236,0.0000046457963,0.00030339236,0.00009549256,0.89582384,0.000032599088,0.0032176413,0.00013680455],"about_ca_topic_score_codex":0.00033987148,"about_ca_topic_score_gemma":0.00029102652,"teacher_disagreement_score":0.09790953,"about_ca_system_score_codex":0.00005551816,"about_ca_system_score_gemma":0.00013554526,"threshold_uncertainty_score":0.4666442},"labels":[],"label_agreement":null},{"id":"W2886231837","doi":"10.1101/390484","title":"Fine Tuning of Histone Demethylase KDM6A/B Improves the Development of Nuclear Transfer Embryo","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Peking University; Tongji University; Chinese Academy of Sciences; York University","keywords":"Somatic cell nuclear transfer; Demethylase; XIST; Reprogramming; Biology; Endogenous retrovirus; Cell biology; Gene knockdown; Maternal to zygotic transition; Histone; Embryo; Molecular biology; Blastocyst; Genetics; X-inactivation; Embryogenesis; Cell culture; Zygote; Cell; Genome; Gene; X chromosome","score_opus":0.00928801217819225,"score_gpt":0.254708639276748,"score_spread":0.24542062709855572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886231837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805487,0.0020408458,0.016479723,0.000039623857,0.00044964039,0.00033336933,0.000061898354,0.00003220663,0.000013987399],"genre_scores_gemma":[0.9866116,0.000102592574,0.012860035,0.000031394047,0.00025431346,0.000036915066,0.0000010366186,0.00009475849,0.0000073312954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982001,0.000058385438,0.0006384381,0.00054746406,0.00023187496,0.00032374414],"domain_scores_gemma":[0.99834794,0.000018365425,0.00019111512,0.0009855962,0.00034870152,0.000108307606],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005139556,0.00037053367,0.00041254994,0.00010344399,0.00009229572,0.000020481802,0.0005605084,0.00038506612,0.000025504509],"category_scores_gemma":[0.000113215596,0.00033399346,0.00016727015,0.00015492583,0.00020135823,0.0000036224812,0.00040291934,0.00027598013,0.000004420133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004388392,0.00006573074,0.00015253795,0.00037926756,0.00020903688,0.0000012859324,0.000052805783,0.00010001861,0.9988009,0.000035392506,0.00013879356,0.000020354777],"study_design_scores_gemma":[0.00030930422,0.00010035048,0.0150773125,0.00014740045,0.00008537256,1.5767078e-8,0.0000074411187,0.00014788925,0.9756912,3.9982834e-7,0.008071245,0.00036206187],"about_ca_topic_score_codex":0.000013510274,"about_ca_topic_score_gemma":0.000009032725,"teacher_disagreement_score":0.023109684,"about_ca_system_score_codex":0.00003795522,"about_ca_system_score_gemma":0.00039353844,"threshold_uncertainty_score":0.9999112},"labels":[],"label_agreement":null},{"id":"W2886688143","doi":"10.1126/sciadv.aat5107","title":"BioBits™ Bright: A fluorescent synthetic biology education kit","year":2018,"lang":"en","type":"article","venue":"Science Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Army Research Office; Paul G. Allen Frontiers Group; Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University; Air Force Office of Scientific Research; David and Lucile Packard Foundation; Defense Threat Reduction Agency; National Science Foundation","keywords":"Fluorescence; Computational biology; Biology; Physics; Optics","score_opus":0.0047903840466935075,"score_gpt":0.33094254000336437,"score_spread":0.32615215595667085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886688143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9780797,0.004516119,0.012276064,0.0002355415,0.0014834722,0.00013689329,0.0000045083616,0.000023678382,0.0032440277],"genre_scores_gemma":[0.9958217,0.00012631869,0.0032762107,0.00013314742,0.00035310967,0.0000112511625,0.0000057949005,0.0000058573546,0.00026662447],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922574,0.0000086749205,0.00009425013,0.000342009,0.000085161795,0.0002441771],"domain_scores_gemma":[0.9995289,0.0000033833226,0.000028851542,0.00025799888,0.00010721142,0.000073675285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014652881,0.00008274578,0.000058506328,0.000065055545,0.00014633007,0.000021799873,0.0002713857,0.000034828714,0.000024453642],"category_scores_gemma":[0.000088349094,0.000069715294,0.000024082727,0.00022793995,0.00066510664,0.000008768972,0.00007155725,0.00002816932,0.000038663184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004058834,0.000019666166,0.000875105,0.000004209601,0.0000014953278,7.3300406e-8,0.00002933131,0.000014641765,0.9162855,0.00026234274,0.0001031703,0.082400404],"study_design_scores_gemma":[0.000050993945,0.00013993966,0.001661543,0.000010585064,0.0000026357911,0.000008372293,0.00005794392,0.000029926025,0.8737924,0.000335578,0.123806864,0.00010320174],"about_ca_topic_score_codex":0.0000071463687,"about_ca_topic_score_gemma":0.000016447108,"teacher_disagreement_score":0.123703696,"about_ca_system_score_codex":0.000011630177,"about_ca_system_score_gemma":0.00017382769,"threshold_uncertainty_score":0.2842907},"labels":[],"label_agreement":null},{"id":"W2886688163","doi":"10.1038/s41467-018-05793-2","title":"The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Kirsten og Freddy Johansens Fond; Medical Research Council; Svend Andersen Fonden; Aase og Ejnar Danielsens Fond","keywords":"Malaria; Computational biology; Cancer research; Virology; Biology; Immunology","score_opus":0.00921440773466274,"score_gpt":0.3111085275304012,"score_spread":0.30189411979573844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886688163","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99209744,0.00413465,0.00072368083,0.00091194693,0.00021874832,0.00045058315,0.000016688113,0.000024648118,0.0014216432],"genre_scores_gemma":[0.99659866,0.000048910322,0.0027963198,0.00011521059,0.00013520345,0.000045826906,0.00006272158,0.000019701862,0.00017747114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917465,0.00008463667,0.00019483166,0.00021472687,0.00011748598,0.00021369045],"domain_scores_gemma":[0.9981749,0.000031287742,0.000057387046,0.001557887,0.00012648286,0.00005206551],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037172184,0.00011222862,0.000075822194,0.0000375957,0.00031320297,0.0000578802,0.0008814752,0.00018574703,0.000005430059],"category_scores_gemma":[0.00013304938,0.000093455215,0.0000425302,0.00018196266,0.00012704816,0.0000044001663,0.00032648433,0.00044719377,0.000008777222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000176376,0.000076351556,0.0013656653,0.0000049941814,0.000014126527,0.000001035354,0.00015147406,0.00019101273,0.99510866,0.0020610872,0.00029461,0.0007133252],"study_design_scores_gemma":[0.00063770893,0.00026561064,0.06570411,0.000054518703,0.000021790442,0.000021801727,0.0004880912,0.00699447,0.82884073,0.00019556837,0.09632568,0.00044994138],"about_ca_topic_score_codex":0.000009411748,"about_ca_topic_score_gemma":0.00083248067,"teacher_disagreement_score":0.16626796,"about_ca_system_score_codex":0.00001878769,"about_ca_system_score_gemma":0.00004205972,"threshold_uncertainty_score":0.38109928},"labels":[],"label_agreement":null},{"id":"W2887070160","doi":"10.1080/15476286.2018.1502589","title":"<i>Lactococcus lactis</i> type III-A CRISPR-Cas system cleaves bacteriophage RNA","year":2018,"lang":"en","type":"article","venue":"RNA Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; CRISPR; Lactococcus lactis; Bacteriophage; RNA; Plasmid; DNA; Nucleic acid; Transcription (linguistics); Molecular biology; Phagemid; Siphoviridae; Genetics; Gene; Bacteria; Escherichia coli","score_opus":0.008784187160595876,"score_gpt":0.31462137328531964,"score_spread":0.30583718612472377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887070160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9725346,0.00135923,0.012966475,0.00008742981,0.0018323391,0.00026334176,0.000030640804,0.00008894896,0.010837001],"genre_scores_gemma":[0.9967815,0.00014359181,0.00053461076,0.0002524248,0.0014066083,0.000016940341,0.000082879655,0.000036923688,0.00074451265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987565,0.000060461334,0.00025710414,0.00044471715,0.000057036745,0.0004241698],"domain_scores_gemma":[0.9991911,0.000015125904,0.00007701786,0.00047926034,0.000115687035,0.000121820805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013978378,0.00023017412,0.00023987479,0.000054530054,0.00010119081,0.000022489829,0.0002585325,0.0003058209,0.00008781133],"category_scores_gemma":[0.000044993772,0.00020980566,0.00008926029,0.00011417078,0.00014446591,0.0000034256532,0.00014949779,0.00011362261,0.00017823579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010990018,0.000018423443,0.000643439,0.000027156115,0.00006114924,0.000006156396,0.000050220373,0.0000045256224,0.9932108,0.00022085456,0.002622598,0.0030247704],"study_design_scores_gemma":[0.0005414371,0.00070497463,0.003377156,0.000017006809,0.000025268619,0.00005797087,0.0000935781,0.000076028846,0.8687337,0.000015138446,0.12606892,0.00028881754],"about_ca_topic_score_codex":0.00005278871,"about_ca_topic_score_gemma":0.000045293666,"teacher_disagreement_score":0.1244771,"about_ca_system_score_codex":0.00002458977,"about_ca_system_score_gemma":0.000047032598,"threshold_uncertainty_score":0.8555626},"labels":[],"label_agreement":null},{"id":"W2887180609","doi":"10.1016/j.tibtech.2018.07.016","title":"Angels and Devils: Dilemmas in Dual-Use Biotechnology","year":2018,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Dual (grammatical number); Dual purpose; The Internet; Dual role; Biotechnology; Political science; Engineering ethics; Biology; Computer science; Engineering; World Wide Web; Chemistry; Philosophy","score_opus":0.014603058064142188,"score_gpt":0.30859287107807537,"score_spread":0.2939898130139332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887180609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954141,0.0011910353,0.0012184418,0.0015383238,0.00013882374,0.000079307334,0.000010309711,0.00007845198,0.00033120508],"genre_scores_gemma":[0.99594223,0.0007658002,0.0027791378,0.00010588956,0.00007767725,0.00002008985,0.000024768447,0.000024657169,0.000259754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872154,0.000024860467,0.00025541618,0.00052055315,0.00005119075,0.00042645782],"domain_scores_gemma":[0.99940217,0.000012225133,0.000040120096,0.0004895643,0.000016469756,0.000039484767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012835173,0.0001971048,0.00021978018,0.0007196085,0.000030486759,0.000012028069,0.00015497969,0.0009297483,0.000028624896],"category_scores_gemma":[0.0001010921,0.00020433015,0.00003131805,0.0005872683,0.0004501612,0.000004787843,0.00028677052,0.00025105267,0.0000089328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051749208,0.000064984226,0.0074494127,0.000009818331,0.000019709158,0.000048355385,0.00005490532,0.000014516542,0.89377165,0.0022272,0.00053616497,0.09575151],"study_design_scores_gemma":[0.00096646184,0.0004948432,0.028874785,0.000022586102,0.0000071298227,0.0001376546,0.00006338207,0.00022365144,0.8821817,0.00027521758,0.08641448,0.00033810243],"about_ca_topic_score_codex":0.00008464204,"about_ca_topic_score_gemma":0.0019815715,"teacher_disagreement_score":0.09541341,"about_ca_system_score_codex":0.000017751987,"about_ca_system_score_gemma":0.000012688811,"threshold_uncertainty_score":0.8332342},"labels":[],"label_agreement":null},{"id":"W2887405675","doi":"10.1016/j.molcel.2018.07.023","title":"Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates","year":2018,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondation Pierre Mercier; Canadian Institutes of Health Research; SystemsX.ch; Carigest","keywords":"Biology; Protein turnover; Protein degradation; Cell biology; Cytokinesis; Proteasome; Cell cycle; Protein biosynthesis; Intracellular; Cell; Biochemistry; Cell division","score_opus":0.00666042578323316,"score_gpt":0.24674808047805494,"score_spread":0.24008765469482177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887405675","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9563487,0.0010971689,0.041208785,0.0000063632506,0.00007014689,0.00023382479,0.000007106046,0.000006102108,0.0010217949],"genre_scores_gemma":[0.9890263,0.000027221871,0.010604958,0.000006148515,0.000054674776,0.000007416677,0.0000126689765,0.000021763475,0.0002388347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999048,0.00006760794,0.00026867536,0.0003130676,0.00012917914,0.00017345493],"domain_scores_gemma":[0.9993133,0.000012948086,0.00012360606,0.00035037997,0.00014043601,0.000059325386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022310119,0.00014889293,0.00016153012,0.000035623816,0.000026641375,0.000011545721,0.00014023288,0.00012527624,0.000014481967],"category_scores_gemma":[0.00005028488,0.00015644227,0.000063270556,0.00007367383,0.00009091753,0.0000051291627,0.00012511239,0.00006857339,0.000002426123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026926196,0.00010048419,0.0027290676,0.00020419263,0.000009992217,0.0000019142765,0.0001534023,0.00013346803,0.9962416,0.000005512712,0.0000064985893,0.00038690952],"study_design_scores_gemma":[0.00029494535,0.00038363753,0.0007556767,0.000041151787,0.000024353862,0.000001457107,0.0001096396,0.00019581127,0.9978345,0.00010373508,0.00010592486,0.00014917702],"about_ca_topic_score_codex":0.00003126087,"about_ca_topic_score_gemma":0.0000025938248,"teacher_disagreement_score":0.032677606,"about_ca_system_score_codex":0.000010446846,"about_ca_system_score_gemma":0.000033138433,"threshold_uncertainty_score":0.63795304},"labels":[],"label_agreement":null},{"id":"W2888407023","doi":"10.1371/journal.pone.0202868","title":"Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Genome editing; Guide RNA; Biology; Cas9; Plasmid; Genetics; Gene; RNA polymerase III; Genome; Transfer RNA; Computational biology; RNA","score_opus":0.025479180819267585,"score_gpt":0.2759975680860567,"score_spread":0.2505183872667891,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888407023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993635,0.0003827105,0.0049676546,0.000056752215,0.00011949257,0.00021486747,0.000009150521,0.000019479005,0.0005949029],"genre_scores_gemma":[0.9922494,0.000019377308,0.0062760133,0.00006692497,0.0011967067,0.00001140655,0.000019215246,0.00003558318,0.00012531747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888533,0.000025762214,0.0002218862,0.00033896434,0.00017423824,0.0003537987],"domain_scores_gemma":[0.9994917,0.0000051135053,0.000047881065,0.00028889984,0.000084433625,0.000081971804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013164211,0.00015580872,0.00017368463,0.00007455155,0.000069020694,0.000021505834,0.00014737945,0.00011604182,0.000043406577],"category_scores_gemma":[0.00006662081,0.0001648935,0.00004987036,0.000116952666,0.00005614732,0.0000017565002,0.00012435253,0.00010749047,0.00002150009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015069939,0.00025568984,0.0016788341,0.00004064262,0.000054813598,0.000007485127,0.00021041972,0.0028573023,0.9946831,0.000002679718,0.000010964484,0.00018300914],"study_design_scores_gemma":[0.000552536,0.0002853886,0.0048866747,0.00011901453,0.000044474084,0.000011129987,0.00007751411,0.03847552,0.9548011,0.000006749816,0.0004315946,0.00030830555],"about_ca_topic_score_codex":0.000019849545,"about_ca_topic_score_gemma":0.00003210632,"teacher_disagreement_score":0.03988199,"about_ca_system_score_codex":0.000034290297,"about_ca_system_score_gemma":0.00002928667,"threshold_uncertainty_score":0.67241615},"labels":[],"label_agreement":null},{"id":"W2888670791","doi":"10.15562/gnc.62","title":"CRISPR as a Versatile Technology for Gene Activation and Genome Editing","year":2018,"lang":"en","type":"article","venue":"Journal of Genes and Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Zinc finger nuclease; Transcription activator-like effector nuclease; Cas9; Biology; Gene; Genome engineering; Computational biology; Genome; Genetics","score_opus":0.004981750588696437,"score_gpt":0.27259606043201123,"score_spread":0.2676143098433148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888670791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9581533,0.002508787,0.038893264,0.00016314491,0.0001596188,0.000059872833,0.000003166896,0.000002100149,0.000056757708],"genre_scores_gemma":[0.99262226,0.00085163413,0.0053802636,0.000067923356,0.0009790821,0.0000018641311,0.0000023265438,0.00000928489,0.000085377964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99962807,0.0000045290744,0.00013361013,0.00009169254,0.00004185235,0.000100257705],"domain_scores_gemma":[0.9996958,0.0000066038233,0.0000829924,0.000060189872,0.00011198903,0.000042422977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099728386,0.00006361362,0.00008788248,0.000053628923,0.00005388705,0.0000140764805,0.000046284087,0.00007663955,0.000005422926],"category_scores_gemma":[0.000022090251,0.000056873523,0.00002869448,0.000032529646,0.00004195111,0.0000034567129,0.000032816555,0.00003447662,4.45468e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034333858,0.0000068443524,0.00015119469,0.000013572808,0.000026283298,6.64196e-7,0.000050194132,0.000028677488,0.991067,0.000010072761,0.00016002898,0.0084511675],"study_design_scores_gemma":[0.0003525305,0.0006598721,0.00034354514,0.0000083405175,0.000018445127,0.00007118534,0.00023772873,0.00006897916,0.94889486,0.00010569651,0.04917723,0.00006157103],"about_ca_topic_score_codex":0.0000017026501,"about_ca_topic_score_gemma":0.0000013219693,"teacher_disagreement_score":0.049017202,"about_ca_system_score_codex":0.000003717592,"about_ca_system_score_gemma":0.00001897104,"threshold_uncertainty_score":0.23192349},"labels":[],"label_agreement":null},{"id":"W2889043728","doi":"10.1101/393231","title":"Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; McGill University Health Centre","funders":"National Institute of General Medical Sciences; Biotechnology and Biological Sciences Research Council; Medical Research Council; National Institutes of Health; Ministry of Education, Culture, Sports, Science and Technology; Canadian Institutes of Health Research; Indiana Clinical and Translational Sciences Institute; McGill University; McGill University Health Centre; British Heart Foundation; National Center for Advancing Translational Sciences; Wellcome Trust; Japan Agency for Medical Research and Development; University of California, Davis","keywords":"CRISPR; Cas9; Conditional gene knockout; Genome editing; Biology; Allele; Computational biology; Genetics; Gene knockout; Cre recombinase; Oligonucleotide; Transgene; Gene; Computer science; Genetically modified mouse; Phenotype","score_opus":0.019210216921186938,"score_gpt":0.2772081651222286,"score_spread":0.25799794820104166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889043728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9356138,0.0043762634,0.057575002,0.00017862917,0.00073746115,0.00054965744,0.00082697347,0.00012999796,0.000012216043],"genre_scores_gemma":[0.97820306,0.00031971495,0.01908838,0.000101054255,0.0019100981,0.0001634177,0.00007444588,0.00013387878,0.000005978288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971039,0.00010594686,0.00077003276,0.0010622232,0.00040753605,0.0005503066],"domain_scores_gemma":[0.99744767,0.000032372478,0.0005743147,0.0008912998,0.00089822407,0.00015614709],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006662488,0.0005199215,0.0005240804,0.00027138146,0.00017866296,0.00006904856,0.0005140434,0.0009846363,0.000044961114],"category_scores_gemma":[0.0006322401,0.00065229577,0.00014691793,0.00029349822,0.00020603053,0.000010787073,0.00056252116,0.0004819653,0.000013559354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015557413,0.00006433498,0.0009365293,0.00024522177,0.00024005001,0.0000035074777,0.000008119658,0.0009787903,0.9962254,0.000023806144,0.0012556766,0.0000030060476],"study_design_scores_gemma":[0.0005086198,0.00018207007,0.0018263407,0.00015148873,0.00012230455,6.0827354e-8,0.0000194638,0.003628387,0.98984885,0.0000016699737,0.0030724343,0.00063829386],"about_ca_topic_score_codex":0.000025955194,"about_ca_topic_score_gemma":0.000009548864,"teacher_disagreement_score":0.042589232,"about_ca_system_score_codex":0.00009861145,"about_ca_system_score_gemma":0.0003436942,"threshold_uncertainty_score":0.99959284},"labels":[],"label_agreement":null},{"id":"W2889282955","doi":"10.1093/nar/gky785","title":"Programmable T7-based synthetic transcription factors","year":2018,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund","keywords":"Biology; Synthetic biology; RNA polymerase; Transcription (linguistics); General transcription factor; Bacterial transcription; Transcription factor II D; RNA polymerase II; Computational biology; Polymerase; Transcription factor; Sigma factor; Eukaryotic transcription; Genetics; DNA; Cell biology; Escherichia coli; Promoter; Gene expression; Gene","score_opus":0.03618843275376969,"score_gpt":0.3693739558263352,"score_spread":0.3331855230725655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889282955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845471,0.00024623986,0.011267968,0.00016417522,0.00014391767,0.00026693125,0.000007478382,0.000038477592,0.0033177063],"genre_scores_gemma":[0.99730355,0.000026746708,0.0012658589,0.000027842976,0.00029639158,0.00003086313,0.00003841999,0.00003598747,0.0009743524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985926,0.00008113253,0.00013210464,0.00035125553,0.00033558608,0.00050730864],"domain_scores_gemma":[0.9992109,0.000015234334,0.000013043889,0.0004194968,0.00020875236,0.00013257336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046954927,0.00012342307,0.00009598172,0.00010490252,0.0001897031,0.000055053522,0.00025739372,0.00015153365,0.00018964442],"category_scores_gemma":[0.000110495865,0.000112833266,0.00007487115,0.00022938056,0.00026540348,0.000003198133,0.000054075554,0.00018146366,0.0000913636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000628518,0.00006476998,0.0019396706,0.000029814795,0.000018031093,0.0000015695292,0.00011418893,0.00004835576,0.98837674,0.00004855273,0.0015633287,0.0077321427],"study_design_scores_gemma":[0.00034291946,0.00080557476,0.003599676,0.000017736513,0.0000060882953,0.000002760749,0.00015488606,0.0012529384,0.8417648,0.000045995504,0.15184665,0.00015996264],"about_ca_topic_score_codex":0.000033471904,"about_ca_topic_score_gemma":0.000031194748,"teacher_disagreement_score":0.1502833,"about_ca_system_score_codex":0.000024004039,"about_ca_system_score_gemma":0.00007398009,"threshold_uncertainty_score":0.4601207},"labels":[],"label_agreement":null},{"id":"W2889416995","doi":"10.1101/402982","title":"Evolution of Bacterial Gene Transfer Agents","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gene; Recombination; Prophage; Biology; Epistasis; Genetics; Selection (genetic algorithm); DNA; Bacteriophage; Escherichia coli","score_opus":0.008882679716619853,"score_gpt":0.23801974095322206,"score_spread":0.2291370612366022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889416995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9569899,0.0012210716,0.039476804,0.000011678736,0.0016079783,0.00033632503,0.0002984328,0.000048605296,0.000009247001],"genre_scores_gemma":[0.99529856,0.00025498174,0.0028460117,0.000021354785,0.0014258763,0.00005136998,0.000003297142,0.00009272731,0.0000058326445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827445,0.000056575926,0.00041613192,0.00068509346,0.00021142427,0.00035634014],"domain_scores_gemma":[0.99846435,0.0000049739124,0.00010549854,0.00096890616,0.00030949494,0.00014677024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000247623,0.00037731606,0.0003454129,0.00011310361,0.00005151504,0.000034735214,0.00039238774,0.0005974249,0.00006721067],"category_scores_gemma":[0.00006258865,0.00043231912,0.00019056488,0.00012837871,0.000105997,0.0000039283045,0.00028124903,0.0002003631,0.000015195415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055444158,0.00006206246,0.0011994876,0.00017652265,0.00013179143,0.0000029564426,0.000003974866,0.00029569716,0.99758434,0.000023632068,0.00046314456,9.4615143e-7],"study_design_scores_gemma":[0.00043470258,0.0001188645,0.034743726,0.0000850269,0.00008402873,1.7248839e-8,8.5680944e-7,0.00016008447,0.9587695,6.298441e-7,0.0051714308,0.00043110736],"about_ca_topic_score_codex":0.000021070562,"about_ca_topic_score_gemma":0.0000026072798,"teacher_disagreement_score":0.038814817,"about_ca_system_score_codex":0.00006822943,"about_ca_system_score_gemma":0.00030271983,"threshold_uncertainty_score":0.99981284},"labels":[],"label_agreement":null},{"id":"W2889479076","doi":"10.1007/978-1-4939-8651-4_10","title":"Creation of DMD Muscle Cell Model Using CRISPR-Cas9 Genome Editing to Test the Efficacy of Antisense-Mediated Exon Skipping","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Exon skipping; Duchenne muscular dystrophy; Genome editing; Exon; CRISPR; Dystrophin; Biology; Mutation; Cell culture; Cancer research; Gene; Molecular biology; Genetics; Alternative splicing","score_opus":0.021384216357327873,"score_gpt":0.4095568078614546,"score_spread":0.38817259150412675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889479076","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46237835,0.00029689583,0.5368874,0.000020998426,0.00008301866,0.00014970836,0.000010677648,0.000004402231,0.00016853657],"genre_scores_gemma":[0.6356558,0.000024024092,0.36407837,0.00007465965,0.00010995843,0.000006240028,0.00002165553,0.000020420284,0.000008854922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855,0.00027622472,0.00043842706,0.00035991182,0.0000748335,0.00030057886],"domain_scores_gemma":[0.9990594,0.00015390139,0.00015284884,0.0004336881,0.0001481459,0.00005203287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008700427,0.00017217947,0.00026987103,0.00013720595,0.00004636549,0.0000056929925,0.00024521572,0.00020172537,0.000006362313],"category_scores_gemma":[0.0011404038,0.00015327231,0.000093972194,0.00028650608,0.0001483984,0.0000020681475,0.00019095383,0.00010570127,9.781785e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019368552,0.0000577714,0.0004624207,0.0000255984,0.000016112877,0.0000012449626,0.00020223671,0.022359617,0.97472626,0.000019048359,0.000003854073,0.0021064891],"study_design_scores_gemma":[0.00038076224,0.00033324127,0.001156746,0.000022597134,0.000025004678,0.000004803209,0.00008586649,0.025523338,0.9718384,0.000083760635,0.00039434124,0.00015115067],"about_ca_topic_score_codex":0.000046920395,"about_ca_topic_score_gemma":0.000011827189,"teacher_disagreement_score":0.17327747,"about_ca_system_score_codex":0.00001556121,"about_ca_system_score_gemma":0.000048051545,"threshold_uncertainty_score":0.62502635},"labels":[],"label_agreement":null},{"id":"W2890107400","doi":"10.1146/annurev-genet-120417-031321","title":"Phage-Encoded Anti-CRISPR Defenses","year":2018,"lang":"en","type":"review","venue":"Annual Review of Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Arms race; Trans-activating crRNA; Bacteria; Computational biology; CRISPR interference; Genetics; Immune system; Gene; Cas9","score_opus":0.019854523749205582,"score_gpt":0.389898921542253,"score_spread":0.3700443977930474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890107400","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00001768307,0.9966335,0.0009882384,0.000013233279,0.0004149204,0.0007564825,0.00034850952,0.000015722337,0.0008116688],"genre_scores_gemma":[0.000018891293,0.99616426,0.0017245738,0.00027544878,0.0007068121,0.000050876195,0.00052081916,0.00011117437,0.00042711807],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973935,0.00015336685,0.0011175842,0.00063695456,0.00028695402,0.00041164135],"domain_scores_gemma":[0.9978627,0.0000346039,0.00048027228,0.0011222183,0.00035034202,0.0001498819],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040803553,0.0005968275,0.0017780284,0.00009051539,0.000046798497,0.000012914396,0.00068257883,0.00041054754,0.000059384016],"category_scores_gemma":[0.00028426404,0.000510864,0.0009006207,0.00027297717,0.0001522596,0.0000022522347,0.00033608917,0.00019074007,0.00008425831],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000023578134,0.00006544457,0.0000032426813,0.1839457,0.0003358998,0.0000064623255,0.000017267268,0.0000025546663,0.0001505034,0.000009284817,0.0492901,0.7661712],"study_design_scores_gemma":[0.00008877706,0.00025454164,0.0000028294583,0.042035114,0.0009205147,0.000067194356,0.0000069775565,9.977999e-7,0.001909385,0.000003590251,0.95422673,0.00048335266],"about_ca_topic_score_codex":0.0000022486354,"about_ca_topic_score_gemma":0.0000020258158,"teacher_disagreement_score":0.9049366,"about_ca_system_score_codex":0.000013865421,"about_ca_system_score_gemma":0.00028555735,"threshold_uncertainty_score":0.9997343},"labels":[],"label_agreement":null},{"id":"W2891365275","doi":"10.1111/pbi.13012","title":"Zinc finger nuclease‐mediated targeting of multiple transgenes to an endogenous soybean genomic locus via non‐homologous end joining","year":2018,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Zinc finger nuclease; Genome editing; Biology; CRISPR; Genetics; Gene targeting; Non-homologous end joining; Cas9; Transgene; Homology directed repair; Zinc finger; Locus (genetics); Nuclease; Gene; Genome engineering; Transcription activator-like effector nuclease; Homologous recombination; Computational biology; DNA repair; Transcription factor; DNA mismatch repair","score_opus":0.010917436590837982,"score_gpt":0.24037864023497404,"score_spread":0.22946120364413605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891365275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95752144,0.0010204789,0.040566128,0.00018530607,0.00035444033,0.0001481311,0.00008669658,0.000044636923,0.000072751434],"genre_scores_gemma":[0.9912548,0.0002712955,0.0077104922,0.00013801304,0.00047938168,0.0000048515567,0.00008360908,0.000044560587,0.000012962165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845356,0.000044310902,0.00046492933,0.00037341987,0.00012728728,0.00053649],"domain_scores_gemma":[0.9991981,0.00002517464,0.00016634147,0.00031878185,0.000096365206,0.0001952767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035219922,0.00024539404,0.00030515282,0.0002415064,0.00021014563,0.00001962391,0.00042954565,0.00049136614,0.00006302525],"category_scores_gemma":[0.00014718663,0.0002370195,0.00010090363,0.00013890941,0.0001819517,0.0000060247835,0.00011295899,0.00033227587,0.000026174048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013531062,0.000067492234,0.00088377733,0.0000121155745,0.00010141235,0.0000645168,0.0002834098,0.00035949788,0.98967355,0.0000031043246,0.00019821832,0.008217591],"study_design_scores_gemma":[0.00067228376,0.0011936511,0.00069862464,0.000021847152,0.00003429476,0.0016973031,0.00020831887,0.001189953,0.9882023,0.000015057269,0.005778439,0.0002879485],"about_ca_topic_score_codex":0.00004463808,"about_ca_topic_score_gemma":0.000107801716,"teacher_disagreement_score":0.033733405,"about_ca_system_score_codex":0.000023124829,"about_ca_system_score_gemma":0.000075816264,"threshold_uncertainty_score":0.9665375},"labels":[],"label_agreement":null},{"id":"W2893391390","doi":"10.1016/j.scr.2018.09.011","title":"Generation of integration-free iPS cell lines from three sickle cell disease patients from the state of Bahia, Brazil","year":2018,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado da Bahia; Instituto Nacional de Ciência e Tecnologia em Medicina Regenerativa; Ministry of Health, British Columbia; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Biology; Induced pluripotent stem cell; Reprogramming; Disease; Peripheral blood mononuclear cell; Karyotype; Germ layer; Cell; Cell culture; Immunology; Cancer research; Embryonic stem cell; Gene; Genetics; Internal medicine; Chromosome; Medicine","score_opus":0.03433696750502609,"score_gpt":0.3316566532569314,"score_spread":0.2973196857519053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2893391390","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857918,0.0018261168,0.01081171,0.000039290382,0.00016788708,0.00028536635,0.00041386907,0.000004706548,0.0006592281],"genre_scores_gemma":[0.99740976,0.00017179566,0.00047175772,0.000018358756,0.00040304646,0.000015968819,0.00042627583,0.00002428498,0.0010587453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863493,0.00013744584,0.0002786343,0.00030764422,0.00041169304,0.00022963926],"domain_scores_gemma":[0.9984061,0.00010782655,0.000077378136,0.00076879247,0.00054175337,0.00009811336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000329414,0.00012460108,0.00012467103,0.000042769905,0.00009046561,0.00002647645,0.0004509188,0.00007052178,0.0000535168],"category_scores_gemma":[0.00005748956,0.000095315474,0.00007089388,0.00012775838,0.00015766025,0.0000054831335,0.00027664134,0.00012609364,0.000016723745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000120098106,0.00013429292,0.009490516,0.000034595036,0.000015422003,3.7676745e-7,0.00038444172,0.00030409702,0.97602063,0.000002073125,0.00586831,0.007625115],"study_design_scores_gemma":[0.00056196813,0.00026212493,0.010632939,0.000017058082,0.0000132685245,1.3962182e-8,0.00011878164,0.0029732543,0.98350215,0.0001632506,0.0016553729,0.000099845915],"about_ca_topic_score_codex":0.0005895021,"about_ca_topic_score_gemma":0.0011020862,"teacher_disagreement_score":0.011617941,"about_ca_system_score_codex":0.000011460636,"about_ca_system_score_gemma":0.00011248506,"threshold_uncertainty_score":0.38868523},"labels":[],"label_agreement":null},{"id":"W2894427028","doi":"10.1101/426973","title":"<i>beditor</i> : A computational workflow for designing libraries of guide RNAs for CRISPR-mediated base editing","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research","keywords":"CRISPR; Workflow; Guide RNA; Computer science; Computational biology; Base (topology); Mutagenesis; RNA; Genome editing; Genome; Biology; Mutation; Genetics; Database; Gene","score_opus":0.011348969401822522,"score_gpt":0.25662211891234626,"score_spread":0.24527314951052373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894427028","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.088964775,0.0013919771,0.90387434,0.00013338985,0.0030622862,0.0012294775,0.00122482,0.000113422866,0.000005516091],"genre_scores_gemma":[0.6798373,0.000053385636,0.3133897,0.00014408703,0.005883547,0.00049245014,0.000029273384,0.0001626979,0.000007586799],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977146,0.000046627127,0.0006703547,0.00082305976,0.00023600092,0.0005093686],"domain_scores_gemma":[0.9976391,0.00019305169,0.00041149062,0.00062673,0.00094475003,0.0001848318],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005765484,0.00046589144,0.00048040578,0.00014468384,0.00015041577,0.000106861364,0.00044406005,0.0005689977,0.000007852265],"category_scores_gemma":[0.0010605826,0.00054181746,0.00027027904,0.00015851544,0.0001409171,0.000012264572,0.0003307662,0.00020190758,0.0000023067741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000117040705,0.000071657996,0.00079648115,0.0008393986,0.00026427247,0.0000021126414,0.0000113644455,0.0059032957,0.96919787,0.00008242123,0.022706915,0.000007150275],"study_design_scores_gemma":[0.00095819245,0.00022643141,0.000969169,0.0003487215,0.00012740055,2.261257e-8,0.0000064207075,0.00797392,0.9604772,0.000021497142,0.028282959,0.0006080949],"about_ca_topic_score_codex":0.0000061273377,"about_ca_topic_score_gemma":0.0000014401068,"teacher_disagreement_score":0.59087247,"about_ca_system_score_codex":0.00004005262,"about_ca_system_score_gemma":0.0006090015,"threshold_uncertainty_score":0.99970335},"labels":[],"label_agreement":null},{"id":"W2895133584","doi":"10.1053/j.semperi.2018.09.014","title":"In search of: Suggesting a course of action for the scientific community to research potential impacts of heritable gene editing on the maternal carrier","year":2018,"lang":"en","type":"review","venue":"Seminars in Perinatology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"HalTech","funders":"","keywords":"CRISPR; Germline; Genome editing; Context (archaeology); Offspring; Germline mutation; Genetics; Reproductive technology; Germline mosaicism; Medicine; Preimplantation genetic diagnosis; Biology; Mutation; Gene; Pregnancy","score_opus":0.08010963072471185,"score_gpt":0.45743400675511287,"score_spread":0.37732437603040103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895133584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6359209,0.36245584,0.00008617121,0.000039586444,0.0004014492,0.00068869337,0.00037997865,0.0000013614739,0.000026018482],"genre_scores_gemma":[0.80416465,0.19502196,0.0002938602,0.0000056870654,0.0001541684,0.00015255787,0.00007789568,0.00003474968,0.000094475465],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982841,0.00049929594,0.00043268251,0.00023130667,0.00018225503,0.00037035783],"domain_scores_gemma":[0.998534,0.0004902984,0.00013549575,0.0005591384,0.00024654527,0.00003452525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003487045,0.00015306061,0.00047909823,0.00020384723,0.00014054359,0.000012518848,0.0005716216,0.0002367291,0.00001918882],"category_scores_gemma":[0.00070379087,0.00010569628,0.00012451944,0.00037644507,0.00044356837,0.0000024470717,0.00034830096,0.0004793874,4.7209178e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009096459,0.0008952411,0.001499796,0.048102707,0.00066041836,0.00003759083,0.0069070146,0.0026687991,0.32393187,0.00035009292,0.00926933,0.6047675],"study_design_scores_gemma":[0.0005695343,0.0018862152,0.0004352537,0.0121230865,0.000110212575,0.0002720051,0.0047020754,0.0005563276,0.5267229,0.000079564015,0.4521264,0.00041638536],"about_ca_topic_score_codex":0.00035286843,"about_ca_topic_score_gemma":0.00033831425,"teacher_disagreement_score":0.6043511,"about_ca_system_score_codex":0.00003831172,"about_ca_system_score_gemma":0.00024211177,"threshold_uncertainty_score":0.43101692},"labels":[],"label_agreement":null},{"id":"W2895140123","doi":"10.1534/g3.118.200461","title":"Double Selection Enhances the Efficiency of Target-AID and Cas9-Based Genome Editing in Yeast","year":2018,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Canadian Institutes of Health Research","keywords":"Genome editing; CRISPR; Selection (genetic algorithm); Multiplex; Cas9; Computational biology; Computer science; Biology; Genetics; Gene; Artificial intelligence","score_opus":0.007028226109623308,"score_gpt":0.2672020532728505,"score_spread":0.26017382716322723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895140123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8723384,0.111124694,0.015716016,0.0000426832,0.00023430891,0.00023685338,0.000012630373,0.000010142257,0.0002842593],"genre_scores_gemma":[0.9899684,0.005198268,0.0039330856,0.00005305693,0.00068043865,0.0000202658,0.000022499778,0.000026619917,0.00009734683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988863,0.00003341718,0.00028698044,0.00033460523,0.00013974354,0.00031899364],"domain_scores_gemma":[0.9994568,0.00001053709,0.00009203083,0.00027202212,0.00011066261,0.000057918136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023990707,0.00017891946,0.00015948732,0.000082585386,0.00010660585,0.00002302178,0.00020655422,0.000110087494,0.000022386439],"category_scores_gemma":[0.0000054657144,0.00015525443,0.000051669056,0.00022337974,0.00018915329,0.0000025158986,0.0001011819,0.00007100939,0.0000039202077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038880517,0.00003049751,0.007818299,0.000040168114,0.000019519473,5.713584e-7,0.00025654284,0.007475369,0.9605018,0.000007853443,0.000017555103,0.023792924],"study_design_scores_gemma":[0.00056020333,0.00035256305,0.0030324736,0.0000096531785,0.000016800243,0.000010963216,0.00018514556,0.0034807448,0.9463746,0.000015965568,0.045766745,0.00019413276],"about_ca_topic_score_codex":0.000025280498,"about_ca_topic_score_gemma":0.00019638872,"teacher_disagreement_score":0.11763001,"about_ca_system_score_codex":0.000013568686,"about_ca_system_score_gemma":0.00007809031,"threshold_uncertainty_score":0.6331092},"labels":[],"label_agreement":null},{"id":"W2896360542","doi":"10.1158/1538-7445.pedca17-b44","title":"Abstract B44: Identification of epigenomic changes induced by H3 K27M mutation in glioblastoma using patient-derived and CRISPR/Cas9 edited cell lines","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Chromatin immunoprecipitation; Histone H3; Epigenomics; Histone; Biology; H3K4me3; Chromatin; Epigenetics; Genetics; Methylation; Histone methylation; DNA methylation; Cancer research; Molecular biology; Gene expression; Gene; Promoter","score_opus":0.03484336375706161,"score_gpt":0.39287898568490126,"score_spread":0.35803562192783966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896360542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99760723,0.0016180058,0.00032426405,0.000055012722,0.00013223736,0.00021480593,0.00002984405,0.000003945532,0.000014634591],"genre_scores_gemma":[0.99929446,0.00032789,0.000045928857,0.000009628893,0.00023334472,0.000031071824,0.000024344616,0.000017410972,0.000015917998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917024,0.00003991298,0.0001840485,0.0002453742,0.00014542631,0.0002149668],"domain_scores_gemma":[0.9994425,0.0000151525155,0.00006006502,0.00016027638,0.00027204343,0.00004993576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024263308,0.00008130416,0.00008927868,0.00013884966,0.00005521031,0.00002040403,0.00008718297,0.00010178629,0.000015128413],"category_scores_gemma":[0.000065679815,0.0000870783,0.0000135735545,0.00020396213,0.00008782047,0.000005254461,0.000063320804,0.00009468062,0.0000016044866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007206385,0.000022951719,0.00017134302,0.0000618326,0.000007484176,7.413405e-7,0.00037923447,0.00012967642,0.9938199,3.2411384e-7,0.00018645772,0.005147976],"study_design_scores_gemma":[0.00027722746,0.0002409833,0.0043514315,0.000027469432,0.0000034211196,0.0000010132067,0.0003129143,0.0005574011,0.99384093,0.0000064334113,0.00029530938,0.0000854747],"about_ca_topic_score_codex":0.00036278818,"about_ca_topic_score_gemma":0.00052497763,"teacher_disagreement_score":0.0050625014,"about_ca_system_score_codex":0.00003445306,"about_ca_system_score_gemma":0.00006618559,"threshold_uncertainty_score":0.355095},"labels":[],"label_agreement":null},{"id":"W2896443010","doi":"10.1038/nbt.4263","title":"Opening options for material transfer","year":2018,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; National Institute of Standards and Technology; National Institutes of Health; Consortium of International Agricultural Research Centers; Pontificia Universidad Católica de Chile; King Mongkut's University of Technology Thonburi; Universiteit Gent; John Innes Foundation; Queensland University of Technology; Woodrow Wilson International Center for Scholars; University of Technology Sydney; University College Cork; University of Tasmania; Cardiff University; Vanderbilt University; London School of Economics and Political Science; Biotechnology and Biological Sciences Research Council; World Health Organization; Wellcome Trust; California Institute of Technology; Kent State University; University of Denver; Sidra Medicine; Leona M. and Harry B. Helmsley Charitable Trust; Genome Center, University of California, Davis; University of California, Davis; U.S. Department of Energy; Simon Fraser University; King's College London; University of Crete; Yale University; Bill and Melinda Gates Foundation; Directorate for Biological Sciences; Imperial College London; Princeton University; McGill University; U.S. Department of Commerce; U.S. Department of Health and Human Services","keywords":"Technology transfer; Gene transfer; Biochemical engineering; Nanotechnology; Business; Materials science; Computer science; Knowledge management; Chemistry; Engineering","score_opus":0.004685464756688784,"score_gpt":0.29858425175709286,"score_spread":0.29389878700040406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896443010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75233614,0.0011783832,0.24221858,0.0016081261,0.0015152356,0.00038959074,0.00009659907,0.000117296615,0.00054001744],"genre_scores_gemma":[0.98803335,0.00006662123,0.010564943,0.00019427214,0.0007328222,0.000033083794,0.00008211161,0.00002041687,0.0002723876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994095,0.000005594804,0.00009316584,0.0002553745,0.00003421679,0.00020216391],"domain_scores_gemma":[0.99966925,0.000003602511,0.000009124924,0.00024370007,0.000048670565,0.00002563327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006575346,0.00009835071,0.00008636245,0.000054789612,0.00007125764,0.000010755041,0.00017947656,0.0009331808,0.000031183372],"category_scores_gemma":[0.000045523546,0.00009513104,0.00005040543,0.000068418,0.00009562183,0.0000012079071,0.000049872695,0.00013988072,0.0000065175577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050921324,0.000008856604,0.000010612613,0.0000063274915,0.00001974488,3.767307e-7,0.000006052421,0.000005244949,0.99108744,0.003983357,0.0017726864,0.003048386],"study_design_scores_gemma":[0.0002236154,0.00025096853,0.000057580684,0.0000028693082,0.0000079756055,0.000014576819,0.000009580407,0.000038095775,0.71883017,0.00010536676,0.2803703,0.00008889561],"about_ca_topic_score_codex":0.0000014808396,"about_ca_topic_score_gemma":0.000019344396,"teacher_disagreement_score":0.27859762,"about_ca_system_score_codex":0.0000046521745,"about_ca_system_score_gemma":0.000016561473,"threshold_uncertainty_score":0.7197545},"labels":[],"label_agreement":null},{"id":"W2896471204","doi":"10.1016/j.jconrel.2018.10.018","title":"Tumor targeted genome editing mediated by a multi-functional gene vector for regulating cell behaviors","year":2018,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Canadian Celiac Association","keywords":"Genome editing; CRISPR; Biology; Cas9; Gene delivery; Cell biology; Gene; Molecular biology; Genetic enhancement; Genetics","score_opus":0.005553121742923587,"score_gpt":0.2538061428772771,"score_spread":0.24825302113435352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896471204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8717449,0.002752686,0.12429288,0.00010486996,0.0006812593,0.00032945967,0.000059030495,0.000009167633,0.000025758865],"genre_scores_gemma":[0.99085337,0.000028063521,0.0061103236,0.00013223894,0.0023751787,0.000021577192,0.000076996585,0.000035982735,0.0003662403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876785,0.000042117543,0.000558959,0.000179229,0.00018647431,0.00026536928],"domain_scores_gemma":[0.9987293,0.00004500276,0.00041904114,0.00013298127,0.00049406785,0.0001796309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037324292,0.00017030662,0.00033185314,0.000076453754,0.000111735506,0.00002390216,0.00012798367,0.000103694765,0.00004320246],"category_scores_gemma":[0.0005642434,0.00014612285,0.0002763927,0.000066474924,0.000043937293,0.0000061313685,0.000025763691,0.00012806516,0.0000027890346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011380502,0.00009643591,0.00013598758,0.000012185738,0.00009933424,0.0000058504484,0.000027417458,0.00083494,0.9953223,6.5843125e-7,0.002176294,0.00015057239],"study_design_scores_gemma":[0.030930487,0.0015820803,0.002099851,0.00002971349,0.00027353977,0.00011505874,0.000119979835,0.011513037,0.9395826,0.0000059881168,0.013386963,0.0003607102],"about_ca_topic_score_codex":0.0000024295125,"about_ca_topic_score_gemma":0.000004071763,"teacher_disagreement_score":0.119108506,"about_ca_system_score_codex":0.000024746696,"about_ca_system_score_gemma":0.00011183909,"threshold_uncertainty_score":0.5958717},"labels":[],"label_agreement":null},{"id":"W2896929167","doi":"10.1007/978-1-4939-8805-1_15","title":"Pooled Lentiviral CRISPR-Cas9 Screens for Functional Genomics in Mammalian Cells","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"CRISPR; Functional genomics; Cas9; Gene knockout; Biology; Computational biology; Gene; Genome editing; Guide RNA; Genetic screen; Genomics; Drug discovery; Function (biology); Genetics; Phenotype; Genome; Bioinformatics","score_opus":0.02085657723877584,"score_gpt":0.4020531646386547,"score_spread":0.3811965873998789,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896929167","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14730987,0.0006327648,0.8507719,0.00009410885,0.000514779,0.0003006947,0.000023009232,0.0000091905595,0.000343702],"genre_scores_gemma":[0.25187418,0.000042403743,0.74670875,0.0005053232,0.00036752556,0.000095104144,0.00012855502,0.00004705294,0.00023107341],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832237,0.00028484783,0.00033691482,0.0005448505,0.000046329173,0.00046467182],"domain_scores_gemma":[0.99942136,0.000043501062,0.00005562605,0.0003513133,0.00006808145,0.000060094106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008387345,0.00021322802,0.00024864668,0.0001665153,0.00003959277,0.0000117144455,0.00021009563,0.00032422962,0.000026229516],"category_scores_gemma":[0.00017364675,0.00022986475,0.00013054315,0.00015217061,0.00014306979,0.0000020633663,0.00013983672,0.00013302216,0.000006263735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012116018,0.000039704486,0.0010851428,0.000012256237,0.000031662126,0.000004036787,0.00002770711,0.00041018415,0.98913026,0.0004680375,0.00016715452,0.008502673],"study_design_scores_gemma":[0.00096018845,0.00039106206,0.0014390877,0.0000062778035,0.000016709162,0.0000091366,0.00004027782,0.0010191051,0.9631652,0.0011869301,0.031498842,0.00026718856],"about_ca_topic_score_codex":0.000037415928,"about_ca_topic_score_gemma":0.00014475625,"teacher_disagreement_score":0.104564324,"about_ca_system_score_codex":0.00003279989,"about_ca_system_score_gemma":0.000057282534,"threshold_uncertainty_score":0.93736124},"labels":[],"label_agreement":null},{"id":"W2897152552","doi":"10.1007/978-1-4939-8669-9_14","title":"Generation and Analysis of Xenopus laevis Models of Retinal Degeneration Using CRISPR/Cas9","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Xenopus; CRISPR; Gene knockdown; Cas9; Genome editing; Biology; Computational biology; Gene knockout; Transgene; Model organism; Gene; Genetics; Gene knockin; Point mutation; Mutation","score_opus":0.044285326377180904,"score_gpt":0.4513800128831154,"score_spread":0.4070946865059345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897152552","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4650532,0.0008291167,0.53397423,0.0000057141915,0.000044211465,0.000048068596,0.0000066856146,0.0000015133013,0.000037250316],"genre_scores_gemma":[0.5451243,0.00006895448,0.45467755,0.000023904991,0.00004187265,0.0000031602528,0.000048487538,0.00000739984,0.00000437307],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884176,0.00033239994,0.00033480523,0.00029623555,0.00004938037,0.00014541892],"domain_scores_gemma":[0.99946004,0.000016291655,0.00010772996,0.00026088956,0.00012502166,0.000029998128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063450565,0.00011544736,0.00028009267,0.00024382875,0.000022587494,0.0000042265797,0.0000849203,0.00017888892,0.000006911903],"category_scores_gemma":[0.00012298475,0.00011794488,0.000080578226,0.0003363661,0.00013758421,0.0000024908875,0.00007599842,0.00004722519,5.382532e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020330783,0.000015520944,0.0023360455,0.0000112789285,0.0001352888,5.1039456e-7,0.00006446582,0.016499577,0.97770286,0.00061116175,0.0000025119743,0.002600446],"study_design_scores_gemma":[0.00014456772,0.00018062198,0.0002684536,0.000003969227,0.00015573978,0.0000034248592,0.00001391016,0.17743137,0.8214092,0.00024826228,0.00004877499,0.00009168054],"about_ca_topic_score_codex":0.00006104619,"about_ca_topic_score_gemma":0.00004766045,"teacher_disagreement_score":0.1609318,"about_ca_system_score_codex":0.00000867933,"about_ca_system_score_gemma":0.000026517537,"threshold_uncertainty_score":0.4809653},"labels":[],"label_agreement":null},{"id":"W2897791282","doi":"10.1089/crispr.2018.0043","title":"A Unified Resource for Tracking Anti-CRISPR Names","year":2018,"lang":"en","type":"letter","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":145,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Toronto","funders":"National Institute of General Medical Sciences; Novo Nordisk Fonden","keywords":"CRISPR; Resource (disambiguation); Computer science; Biology; Genetics; Gene; Computer network","score_opus":0.018560631475609244,"score_gpt":0.3178383942852925,"score_spread":0.2992777628096832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897791282","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02983185,0.020108007,0.28231752,0.6568679,0.0056379717,0.0017099583,0.0002779374,0.00011730461,0.0031315594],"genre_scores_gemma":[0.14069629,0.0027934283,0.006131363,0.66484076,0.15885822,0.00014268306,0.0010721986,0.0008659787,0.024599075],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980164,0.00013317299,0.00045448742,0.0004175318,0.00030004437,0.0006783387],"domain_scores_gemma":[0.99864084,0.0000769157,0.0002681392,0.0006767982,0.0002437442,0.00009358923],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007211189,0.0004166747,0.0003634876,0.000102684935,0.0004587541,0.00023006632,0.0008734082,0.0006890109,0.000056343295],"category_scores_gemma":[0.00019935312,0.00030468885,0.00043638336,0.00008211229,0.00015358803,0.0000042170755,0.00013948912,0.0013421187,0.000013772609],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043489013,0.000010257318,0.000014057482,0.00006662255,0.00019591485,0.00003226286,0.00012230677,0.00010665334,0.024149623,0.000003475465,0.97380537,0.0014499971],"study_design_scores_gemma":[0.0004890489,0.00023919082,0.000048474405,0.000088979665,0.00016448055,0.00071285956,0.00011412625,0.00007064579,0.060204897,0.00015574865,0.93731904,0.00039251702],"about_ca_topic_score_codex":0.0000038647695,"about_ca_topic_score_gemma":0.0000033312297,"teacher_disagreement_score":0.27618617,"about_ca_system_score_codex":0.000028005183,"about_ca_system_score_gemma":0.00011908634,"threshold_uncertainty_score":0.9999405},"labels":[],"label_agreement":null},{"id":"W2898144596","doi":"10.1242/dmm.037515","title":"Zebrafish knock-ins swim into the mainstream","year":2018,"lang":"en","type":"editorial","venue":"Disease Models & Mechanisms","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"CRISPR; Zebrafish; Genome editing; Cas9; Gene knockin; Computational biology; Forward genetics; Biology; Computer science; Mutation; Genetics; Mutant; Gene","score_opus":0.0052841807438759126,"score_gpt":0.2676262014335832,"score_spread":0.26234202068970724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898144596","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0047901985,0.0040664305,0.36743918,0.00019025696,0.6205822,0.0007850146,0.00081944815,0.00012868157,0.0011985934],"genre_scores_gemma":[0.16601779,0.001271021,0.0023410043,0.00037139814,0.8217961,0.00034759316,0.004694864,0.0003109262,0.0028492627],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975224,0.00006897548,0.00032832255,0.0009050742,0.0006422179,0.00053297693],"domain_scores_gemma":[0.997926,0.00003533493,0.00011641209,0.0013059495,0.00024809202,0.0003682223],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026198765,0.0005536918,0.00031704895,0.00006600679,0.00023166077,0.00011025144,0.00083494413,0.0007063639,0.00007486398],"category_scores_gemma":[0.00019007573,0.00045396632,0.00035143388,0.000095797695,0.00009296426,0.0000058500477,0.00045046423,0.00035487438,0.000056252215],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015002697,0.000094783194,5.4098473e-7,0.00012363424,0.00020190833,0.000018492949,0.00018267847,0.0019514721,0.017128702,0.00068953173,0.97728014,0.0021780625],"study_design_scores_gemma":[0.0007825205,0.0003427499,0.000006876054,0.00012654018,0.0004022304,0.0000019005398,0.00009733045,0.0072155595,0.027646514,0.019899914,0.94236535,0.0011125087],"about_ca_topic_score_codex":0.000065704575,"about_ca_topic_score_gemma":0.000100925536,"teacher_disagreement_score":0.36509818,"about_ca_system_score_codex":0.00004345488,"about_ca_system_score_gemma":0.000430104,"threshold_uncertainty_score":0.9997912},"labels":[],"label_agreement":null},{"id":"W2898677375","doi":"10.3390/v10110602","title":"CRISPRStudio: A User-Friendly Software for Rapid CRISPR Array Visualization","year":2018,"lang":"en","type":"article","venue":"Viruses","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"CRISPR; Computer science; Trans-activating crRNA; Computational biology; Biology; Genetics; Genome editing; Gene","score_opus":0.016774567387429443,"score_gpt":0.3459441328392829,"score_spread":0.32916956545185344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898677375","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10545643,0.0011063841,0.8923319,0.00003412504,0.00047725305,0.00026626757,0.000059060694,0.00006017333,0.00020843995],"genre_scores_gemma":[0.977309,0.00022246479,0.019259406,0.0010270688,0.0015010108,0.00010819941,0.00012259146,0.00006908554,0.00038118236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919134,0.000016948263,0.00016373712,0.00030035223,0.00008743961,0.00024020682],"domain_scores_gemma":[0.9994171,0.00001724862,0.00004223035,0.00027829848,0.00018269493,0.00006238324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009928814,0.00014813058,0.00011756452,0.00004275268,0.00012423907,0.000029505869,0.00013623374,0.00010352513,0.000045769604],"category_scores_gemma":[0.00026965604,0.00014473608,0.000065232896,0.00010514184,0.00006011217,0.0000051589286,0.000045084533,0.00002900446,0.000024950463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084755164,0.000044780627,0.0014225978,0.000038310303,0.000057364414,3.8253484e-7,0.00006805764,0.000036907968,0.92958444,0.00014442227,0.06641459,0.002103379],"study_design_scores_gemma":[0.0002563645,0.00037671922,0.0005191167,0.00000762462,0.000015751153,0.000002195295,0.000040215218,0.000017929482,0.576009,0.000012214927,0.42261335,0.00012955896],"about_ca_topic_score_codex":0.000010564493,"about_ca_topic_score_gemma":0.000034988723,"teacher_disagreement_score":0.87307245,"about_ca_system_score_codex":0.000007527283,"about_ca_system_score_gemma":0.000035934394,"threshold_uncertainty_score":0.5902166},"labels":[],"label_agreement":null},{"id":"W2898972432","doi":"10.1038/s41588-018-0254-1","title":"Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens","year":2018,"lang":"en","type":"article","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":204,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institutes of Health","keywords":"Phagocytosis; Biology; Filopodia; RAC1; Phagosome; Cell biology; Gene; Actin; Genetics; Signal transduction","score_opus":0.006954892547312249,"score_gpt":0.29358703752723875,"score_spread":0.2866321449799265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898972432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95761263,0.00933946,0.032166805,0.000027226528,0.00040629404,0.0001857784,0.000029883591,0.000015401452,0.00021652643],"genre_scores_gemma":[0.9922121,0.0003853882,0.0063616596,0.00013011653,0.0006136066,0.000004025833,0.00004209244,0.00004301689,0.00020798258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987401,0.000028776512,0.00036237572,0.00037948095,0.0002174795,0.00027180745],"domain_scores_gemma":[0.99886686,0.000008813987,0.00012293555,0.00061544764,0.00029731562,0.00008865917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017022972,0.00019021943,0.00016377674,0.00009752772,0.000076374345,0.000018628247,0.0002781601,0.00040185187,0.000025698706],"category_scores_gemma":[0.000096730444,0.00020490157,0.000099961806,0.0002193701,0.00014534603,0.000002621637,0.00011696851,0.0001509791,0.0000059370154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025911873,0.000026939031,0.007676195,0.000026191472,0.000036641013,6.5471767e-7,0.000056615725,0.0008814249,0.9893246,0.00000957601,0.00036986775,0.001565332],"study_design_scores_gemma":[0.0002668622,0.00023076625,0.04908864,0.000010480232,0.000052838655,0.000011032696,0.000044374887,0.0015333134,0.9370388,0.000043376363,0.011457139,0.00022241077],"about_ca_topic_score_codex":0.0000052085643,"about_ca_topic_score_gemma":0.000017437365,"teacher_disagreement_score":0.052285884,"about_ca_system_score_codex":0.000017087417,"about_ca_system_score_gemma":0.00005420041,"threshold_uncertainty_score":0.8355644},"labels":[],"label_agreement":null},{"id":"W2899187507","doi":"10.20944/preprints201811.0018.v1","title":"Methods of CRISPR/Cas9 Exon Skipping for Duchenne Muscular Dystrophy","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Alberta Innovates; University of Alberta; Japan Society for the Promotion of Science; Women and Children's Health Research Institute; Children's Health Research Institute; Muscular Dystrophy Canada; Canadian Institutes of Health Research; Parent Project Muscular Dystrophy","keywords":"CRISPR; Genome editing; Duchenne muscular dystrophy; Exon skipping; Dystrophin; Cas9; Genetic enhancement; Muscular dystrophy; Medicine; Biology; Genetics; Computational biology; Bioinformatics; Exon; Gene; Alternative splicing","score_opus":0.08335447276990914,"score_gpt":0.44115536104520814,"score_spread":0.357800888275299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899187507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.66902816,0.00089538016,0.32783517,0.000048252336,0.00082067057,0.00065347843,0.000051813637,0.000034358756,0.0006326948],"genre_scores_gemma":[0.93256533,0.0003000513,0.06526131,0.000042326606,0.0008532189,0.0002612837,0.0001975212,0.00009287652,0.00042606035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975116,0.00013136132,0.000613423,0.0011235548,0.0001789412,0.00044108884],"domain_scores_gemma":[0.9974484,0.000041027528,0.00029667895,0.0016975012,0.00037656285,0.00013983912],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00092766323,0.00043790488,0.0005564456,0.000119967626,0.00006741619,0.000014241437,0.00066906743,0.00062541815,0.000106777574],"category_scores_gemma":[0.00063190033,0.00048062054,0.00054514874,0.000080022844,0.00012642927,0.0000031161799,0.0016455264,0.00032216744,0.000024810404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093017516,0.000079618556,0.006615013,0.0007463478,0.0004007251,0.0000016091166,0.00016506904,0.002730022,0.98721653,0.00004029936,0.00014331807,0.0017684553],"study_design_scores_gemma":[0.00044699066,0.00010418152,0.011547998,0.00012751478,0.00015116735,0.0000074811405,0.00004805774,0.00051481277,0.9554806,0.0004746609,0.030627014,0.0004695232],"about_ca_topic_score_codex":0.000052685566,"about_ca_topic_score_gemma":0.000005587948,"teacher_disagreement_score":0.26353717,"about_ca_system_score_codex":0.000034434455,"about_ca_system_score_gemma":0.00012242836,"threshold_uncertainty_score":0.99976456},"labels":[],"label_agreement":null},{"id":"W2899256508","doi":"10.1534/genetics.118.301456","title":"Transgenerational Epigenetic Inheritance Is Negatively Regulated by the HERI-1 Chromodomain Protein","year":2018,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"RNA interference; Biology; Chromodomain; Genetics; Epigenetics; Gene silencing; RNA silencing; Gene; Genetic screen; Cell biology; RNA; Mutant","score_opus":0.009120461304376815,"score_gpt":0.2721878289833146,"score_spread":0.2630673676789378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899256508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9324141,0.0037981481,0.061849125,0.0007855002,0.00014614666,0.00042313474,0.000070869224,0.000022510107,0.0004904768],"genre_scores_gemma":[0.9899489,0.00014366565,0.0064006434,0.00057270244,0.0006414345,0.000063724976,0.00007326519,0.000048315374,0.002107327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871916,0.0000630124,0.0002563756,0.00040730077,0.00021315877,0.0003409828],"domain_scores_gemma":[0.9992226,0.000006979982,0.000057304194,0.0004860956,0.00013605114,0.00009097104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014107394,0.00022667897,0.00012732136,0.000019769144,0.00020237762,0.00004435069,0.00031749916,0.00015985809,0.0001198229],"category_scores_gemma":[0.000021813361,0.00019342307,0.00007692462,0.00015779742,0.00026390716,0.0000024218668,0.000062870284,0.000093458846,0.000029951652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002236565,0.0000259625,0.0000931288,0.000008008539,0.000045597426,5.7009623e-7,0.00018696307,0.0002376538,0.983318,0.000026610884,0.012950118,0.003085055],"study_design_scores_gemma":[0.0003610025,0.00031161302,0.0013063997,0.000009787818,0.0000137529005,0.000012837548,0.00003503457,0.0009784593,0.8840431,0.0001481689,0.112537436,0.00024241609],"about_ca_topic_score_codex":0.0000067509895,"about_ca_topic_score_gemma":0.000065380125,"teacher_disagreement_score":0.09958732,"about_ca_system_score_codex":0.000014479554,"about_ca_system_score_gemma":0.00007268429,"threshold_uncertainty_score":0.7887564},"labels":[],"label_agreement":null},{"id":"W2899342278","doi":"10.1016/j.omtn.2018.10.015","title":"Overcoming the Undesirable CRISPR-Cas9 Expression in Gene Correction","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"Cystic Fibrosis Canada; Canadian Institutes of Health Research; Cystic Fibrosis Foundation Therapeutics","keywords":"CRISPR; Gene; Computational biology; Expression (computer science); Genetics; Gene expression; Biology; Computer science; Programming language","score_opus":0.009627486999189975,"score_gpt":0.28074911113221446,"score_spread":0.2711216241330245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899342278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89949566,0.0018033116,0.09670167,0.000115605915,0.00054940506,0.00021169039,0.0000016271196,0.000025205858,0.0010958047],"genre_scores_gemma":[0.99696815,0.00035251104,0.0013003838,0.00064078794,0.00027785552,0.000024643381,0.00001625019,0.000047926653,0.00037146188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892926,0.00008143411,0.00019073777,0.00034435655,0.00015070551,0.0003035189],"domain_scores_gemma":[0.9993312,0.000010018842,0.000044443215,0.0005115185,0.000049898652,0.000052959967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022897377,0.00018815261,0.00012523758,0.000054038297,0.00013217393,0.000040464816,0.00025557296,0.00015241154,0.00006338041],"category_scores_gemma":[0.00003220515,0.00015083703,0.00008916581,0.00016521975,0.000085460946,0.00000538581,0.00008711577,0.00013472348,0.000022300623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009099263,0.000035034693,0.00083486404,0.0000026351247,0.000020153533,0.0000050841654,0.00015393183,0.0005316397,0.99142265,0.00001276577,0.00081823516,0.006071985],"study_design_scores_gemma":[0.00061635574,0.00023877255,0.0030140972,0.000017716915,0.0000051505012,0.000020763258,0.00008381781,0.0009112332,0.96154267,0.000076526485,0.033278294,0.00019459694],"about_ca_topic_score_codex":0.000030564424,"about_ca_topic_score_gemma":0.000017611792,"teacher_disagreement_score":0.0974725,"about_ca_system_score_codex":0.000024670182,"about_ca_system_score_gemma":0.00002732262,"threshold_uncertainty_score":0.61509556},"labels":[],"label_agreement":null},{"id":"W2899381247","doi":"10.1038/s41598-018-34738-4","title":"Effects of CRISPR/Cas9 dosage on TICAM1 and RBL gene mutation rate, embryonic development, hatchability and fry survival in channel catfish","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Microinjection; Biology; Catfish; Cas9; CRISPR; Embryo; Andrology; Guide RNA; Molecular biology; Gene; Genetics; Cell biology; Medicine","score_opus":0.005834203167220407,"score_gpt":0.2644452104444918,"score_spread":0.25861100727727143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899381247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99629205,0.0004245331,0.0017724307,0.00001961838,0.0011469298,0.00022959623,0.000001138824,0.000006963523,0.00010673923],"genre_scores_gemma":[0.99925697,0.000017472134,0.00035148693,0.000011524321,0.000050239396,0.000013992302,0.00003093444,0.000009827138,0.00025752644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988797,0.000040042753,0.0002460419,0.0005268508,0.00012235908,0.00018506085],"domain_scores_gemma":[0.9994578,0.000023059782,0.00008247042,0.0002872309,0.000080444406,0.00006899744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084995286,0.000113610295,0.00013636166,0.0000773366,0.00008088645,0.000036693702,0.00004483426,0.00007948542,0.000002849111],"category_scores_gemma":[0.00020993337,0.000110309345,0.000020810141,0.00012979773,0.00019674642,0.0000052380756,0.00007768403,0.00004606948,9.699327e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021585513,0.000051252147,0.0056082825,0.00012228767,0.000013408899,0.000037492722,0.00044551396,0.000033905053,0.9919709,0.000002797157,0.00015340047,0.0015391578],"study_design_scores_gemma":[0.00019860924,0.00009108269,0.11788993,0.000027380916,0.000006714834,0.000029915747,0.00003823803,0.00009345748,0.88062495,0.00013450031,0.0007534793,0.00011175843],"about_ca_topic_score_codex":0.000017235003,"about_ca_topic_score_gemma":0.00014528148,"teacher_disagreement_score":0.11228165,"about_ca_system_score_codex":0.000011075017,"about_ca_system_score_gemma":0.000067017994,"threshold_uncertainty_score":0.44982845},"labels":[],"label_agreement":null},{"id":"W2899654256","doi":"10.1016/j.gfs.2018.10.005","title":"CRISPR versus GMOs: Public acceptance and valuation","year":2018,"lang":"en","type":"article","venue":"Global Food Security","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Science Foundation","keywords":"CRISPR; Food security; Food safety; Willingness to pay; Valuation (finance); Business; Genetically modified food; Biotechnology; Genetically modified organism; Agriculture; Marketing; Biology; Food science; Economics; Gene; Genetics; Ecology","score_opus":0.02165082605296896,"score_gpt":0.3324249476220954,"score_spread":0.3107741215691264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899654256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849762,0.0018196307,0.008434725,0.0001440931,0.0005164001,0.00010103773,0.000039843846,0.000023700957,0.0039444184],"genre_scores_gemma":[0.99895126,0.000094978626,0.0003978823,0.0000959114,0.00040166595,0.000006475313,0.000034469114,0.000006306656,0.0000110750825],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993117,0.000022484337,0.000098175515,0.00025895474,0.000105314706,0.00020340184],"domain_scores_gemma":[0.9995737,0.0000037036834,0.000024401956,0.00021505188,0.0000943295,0.000088776505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010555782,0.000104834624,0.000073302675,0.000010560632,0.00007359392,0.000038127535,0.000107080166,0.00009905059,0.000020132264],"category_scores_gemma":[0.000099167955,0.00011120516,0.00003351295,0.000091507274,0.000070648166,0.0000051370935,0.00010383961,0.000039995706,0.00001141468],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005515653,0.0014157222,0.129154,0.000631246,0.0025854593,0.000022524262,0.003747138,0.0002727736,0.28341576,0.16212316,0.09797326,0.3131433],"study_design_scores_gemma":[0.009532047,0.011809716,0.1006026,0.000044434983,0.00019648635,0.000102655635,0.0010352834,0.0039967215,0.42413688,0.024866536,0.42153475,0.0021419222],"about_ca_topic_score_codex":0.000009234353,"about_ca_topic_score_gemma":0.00029768134,"teacher_disagreement_score":0.3235615,"about_ca_system_score_codex":0.000016341863,"about_ca_system_score_gemma":0.000030738836,"threshold_uncertainty_score":0.4534815},"labels":[],"label_agreement":null},{"id":"W2900039373","doi":"10.20944/preprints201811.0159.v1","title":"A Multiplex CRISPR/Cas9 System for Use as an Anti-BmNPV Therapeutic","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Genome editing; Biology; Subgenomic mRNA; Multiplex; Computational biology; Genome engineering; Gene; Transcription activator-like effector nuclease; Genome; Genetics","score_opus":0.09654238614321489,"score_gpt":0.39486469236777133,"score_spread":0.29832230622455647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900039373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96904314,0.0004639824,0.027156778,0.000040538423,0.0012447707,0.0013212449,0.000119052995,0.00015138401,0.00045912815],"genre_scores_gemma":[0.99510175,0.00016602958,0.0018548492,0.00012666287,0.0010384419,0.00040541549,0.00042727933,0.00014012858,0.0007394638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971649,0.00010928778,0.00049872923,0.0014655327,0.00021761702,0.00054391794],"domain_scores_gemma":[0.9970902,0.00003283223,0.00020851754,0.0021297869,0.00031111477,0.00022753185],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048607265,0.00054046133,0.00047846613,0.00010005309,0.00013078832,0.00007043784,0.00076013326,0.0007300783,0.0000656868],"category_scores_gemma":[0.00018320113,0.0005680518,0.00036266213,0.000060507406,0.00010004718,0.000008135355,0.0011273819,0.00033137287,0.00019116317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026287313,0.00020436021,0.10396851,0.00089575996,0.0005671994,0.000009669485,0.0003568746,0.0024315813,0.89006674,0.00009271885,0.00017753213,0.00096616003],"study_design_scores_gemma":[0.00085127156,0.00019145205,0.06571777,0.00017185922,0.00017309784,0.000043126296,0.00016664044,0.0029267932,0.90153754,0.00010674178,0.027249832,0.00086388225],"about_ca_topic_score_codex":0.00017679602,"about_ca_topic_score_gemma":0.00003627727,"teacher_disagreement_score":0.038250744,"about_ca_system_score_codex":0.00005848503,"about_ca_system_score_gemma":0.00015889041,"threshold_uncertainty_score":0.9996771},"labels":[],"label_agreement":null},{"id":"W2900564760","doi":"10.3390/jpm8040038","title":"Applications of CRISPR/Cas9 for the Treatment of Duchenne Muscular Dystrophy","year":2018,"lang":"en","type":"review","venue":"Journal of Personalized Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Duchenne muscular dystrophy; Dystrophin; Cas9; Exon skipping; Medicine; Muscular dystrophy; Genetic enhancement; Bioinformatics; Computational biology; Biology; Genetics; Gene; Exon; Alternative splicing","score_opus":0.03045498754806557,"score_gpt":0.4020737553894709,"score_spread":0.3716187678414053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900564760","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006178042,0.9339568,0.06501067,0.000086007756,0.00021855334,0.0005872168,0.000052201452,0.0000010951926,0.000025650337],"genre_scores_gemma":[0.00018418732,0.99549943,0.001684646,0.000011719558,0.0021459328,0.00007502283,0.0000490221,0.000030233123,0.00031983329],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987012,0.000037931863,0.0007677861,0.00015389935,0.00020310671,0.0001360617],"domain_scores_gemma":[0.99828124,0.00011389642,0.00078884413,0.00034107355,0.0003969053,0.00007801546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033356468,0.00022874624,0.0011005211,0.000106504194,0.00003302082,0.000002453019,0.00026309318,0.0001563458,0.000037369566],"category_scores_gemma":[0.00009986585,0.00012060439,0.0008055003,0.00012018821,0.00022334076,0.0000012052839,0.000015064909,0.00007468204,4.2816384e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020831655,0.00037465902,0.0000030660724,0.01051946,0.003766171,0.0000050703375,0.00050296885,0.000017668215,0.00839522,0.00009928739,0.0069798864,0.96912825],"study_design_scores_gemma":[0.0012029703,0.0022556887,0.0000016556063,0.0014019174,0.0027491648,0.000102462545,0.00012523627,0.000005494832,0.0012315915,0.000010307953,0.9908214,0.000092109665],"about_ca_topic_score_codex":0.000007748079,"about_ca_topic_score_gemma":0.0000016916878,"teacher_disagreement_score":0.98384154,"about_ca_system_score_codex":0.000030150632,"about_ca_system_score_gemma":0.0001727489,"threshold_uncertainty_score":0.49181044},"labels":[],"label_agreement":null},{"id":"W2900586415","doi":"10.1186/s13059-018-1580-4","title":"Conferring DNA virus resistance with high specificity in plants using virus-inducible genome-editing system","year":2018,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Transgenic Science and Technology Program; Chinese Academy of Sciences; National Natural Science Foundation of China; National Key Research and Development Program of China; University of Minnesota","keywords":"Biology; Nicotiana benthamiana; CRISPR; Arabidopsis; Genome editing; Cas9; Genome; Transgene; Genetics; Virus; Computational biology; Genetically modified crops; Virology; Gene; Plant virus; DNA sequencing; Guide RNA; Deep sequencing","score_opus":0.01736828481400573,"score_gpt":0.28241442378399606,"score_spread":0.26504613896999035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900586415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853988,0.0010809534,0.011468102,0.000012162353,0.00034008978,0.00020298306,0.000104729785,0.000032694934,0.0013594298],"genre_scores_gemma":[0.996089,0.00006800766,0.0023050003,0.00004570558,0.00123626,0.000013595885,0.00011148322,0.000038380134,0.00009255643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837846,0.000066228844,0.00032252257,0.0006094208,0.00007746871,0.00054591714],"domain_scores_gemma":[0.99929225,0.000011193395,0.00010931662,0.0004267863,0.00006839717,0.00009206254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026020946,0.00024448545,0.00029445085,0.000116754185,0.00012473823,0.000022077978,0.00024646363,0.00022723661,0.000027301308],"category_scores_gemma":[0.000018010598,0.00023294626,0.000040574065,0.00013467878,0.00014554581,0.0000044993126,0.00013140604,0.00012963278,0.000019696088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012440204,0.000017396344,0.0017225526,0.00003963175,0.000039387167,0.000016586351,0.00009364196,0.0005087023,0.9972182,0.00014264266,0.000008151595,0.00006872211],"study_design_scores_gemma":[0.0010491394,0.00044157886,0.023501355,0.0000866609,0.000021203445,0.00009021826,0.0004213074,0.00021249712,0.94636905,0.000027761114,0.02716503,0.0006141748],"about_ca_topic_score_codex":0.00023878735,"about_ca_topic_score_gemma":0.0014997642,"teacher_disagreement_score":0.05084911,"about_ca_system_score_codex":0.00008593229,"about_ca_system_score_gemma":0.00006529349,"threshold_uncertainty_score":0.9499273},"labels":[],"label_agreement":null},{"id":"W2901411615","doi":"10.1038/s41586-018-0733-7","title":"Linking a cell-division gene and a suicide gene to define and improve cell therapy safety","year":2018,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Suicide gene; Thymidine kinase; Genetic enhancement; Gene; Genome editing; Biology; Cell; Cell therapy; Cyclin-dependent kinase 1; Computational biology; Induced pluripotent stem cell; Genome engineering; Genome; Herpes simplex virus; Cell cycle; Genetics; Virus; Embryonic stem cell","score_opus":0.003637863007031136,"score_gpt":0.2667357560798675,"score_spread":0.2630978930728364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901411615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9757385,0.017513627,0.0059285522,0.00017912932,0.00015468843,0.0001602432,0.000020044514,0.000011492848,0.00029368507],"genre_scores_gemma":[0.9893917,0.0014078922,0.0074846107,0.0010296027,0.0003775664,0.0000045697466,0.000039088936,0.00002198272,0.00024302183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993051,0.000010932899,0.00009990491,0.00032059447,0.00007715884,0.00018629212],"domain_scores_gemma":[0.9996096,0.000010015541,0.000023229406,0.00020358001,0.000059144204,0.00009445613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010059866,0.00013826911,0.00010136902,0.00003134444,0.000072738825,0.00002380872,0.00007929638,0.0005094631,0.000005329763],"category_scores_gemma":[0.000019101217,0.00012053517,0.000027863554,0.000060004953,0.000025330739,0.0000017783209,0.00011203159,0.0002680503,0.000002351991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063924366,0.000012502146,0.0008686868,0.000013049509,0.0000075173057,0.0000015040679,0.00009296584,0.000018577317,0.9847622,0.0000023192506,0.00030420697,0.013852576],"study_design_scores_gemma":[0.0006004003,0.00037626943,0.0066027613,0.0000086163545,0.000006372276,0.000008455907,0.000012473554,0.000106455496,0.9595884,0.000015270587,0.03251607,0.00015842564],"about_ca_topic_score_codex":0.000007376358,"about_ca_topic_score_gemma":0.000015393205,"teacher_disagreement_score":0.032211863,"about_ca_system_score_codex":0.0000049438986,"about_ca_system_score_gemma":0.000014976259,"threshold_uncertainty_score":0.49152815},"labels":[],"label_agreement":null},{"id":"W2901672380","doi":"10.1534/g3.118.200778","title":"CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in <i>Caenorhabditis elegans</i>","year":2018,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"CRISPR; Biology; ORFS; Genetics; Cas9; Caenorhabditis elegans; Gene; Computational biology; Genome; Null allele; Open reading frame; Allele","score_opus":0.05917931918555822,"score_gpt":0.3652300367463614,"score_spread":0.30605071756080315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901672380","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17768174,0.2850049,0.5350604,0.00029764877,0.0009375623,0.00071663177,0.000105409126,0.000015182752,0.00018052984],"genre_scores_gemma":[0.89786005,0.047095932,0.05182114,0.0003388636,0.0020453576,0.00017424802,0.00015906189,0.00006667449,0.00043868122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852586,0.000098961966,0.0004440988,0.00040978432,0.00012595633,0.00039532353],"domain_scores_gemma":[0.9988764,0.000088467554,0.00011186619,0.00060497236,0.00025308985,0.00006523192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044899486,0.00022189578,0.00024239061,0.00009901997,0.0001384746,0.000019834895,0.00035450354,0.0002026843,0.00002708911],"category_scores_gemma":[0.00003503581,0.00019830256,0.00014262603,0.00019785696,0.00019334767,0.0000028453103,0.00012581274,0.00007504499,0.0000054628895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003027871,0.00002936218,0.0009968807,0.000024162948,0.00006120658,4.3557685e-7,0.00018668825,0.005537544,0.7267829,0.000101771904,0.0011414242,0.26510736],"study_design_scores_gemma":[0.0004362709,0.00040090844,0.0008998176,0.0000043491495,0.00005361632,0.000016175329,0.00012769108,0.0028346577,0.67188215,0.00008881362,0.32305408,0.0002014489],"about_ca_topic_score_codex":0.000030358508,"about_ca_topic_score_gemma":0.00075800065,"teacher_disagreement_score":0.7201783,"about_ca_system_score_codex":0.000017298842,"about_ca_system_score_gemma":0.000101063444,"threshold_uncertainty_score":0.80865437},"labels":[],"label_agreement":null},{"id":"W2901761318","doi":"10.1051/medsci/2018215","title":"Le système CRISPR-Cas","year":2018,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Molecular biology; Biology; Humanities; Philosophy","score_opus":0.030228629649951152,"score_gpt":0.35960158269283066,"score_spread":0.3293729530428795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901761318","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006861282,0.9589481,0.014783234,0.00042763643,0.0021164895,0.00046293656,0.00006052154,0.00003035002,0.022484656],"genre_scores_gemma":[0.027806854,0.96052194,0.0034104409,0.00021317218,0.0029892623,0.00006802004,0.000095354895,0.000079091085,0.004815897],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965084,0.00017214371,0.0007477614,0.0012777161,0.00041018843,0.000883777],"domain_scores_gemma":[0.9986543,0.00008136621,0.00026547606,0.0006535367,0.000120967525,0.00022435612],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00096062664,0.00066751754,0.00094553654,0.00017303071,0.0005893648,0.0001803829,0.0011821316,0.0005944468,0.00020968722],"category_scores_gemma":[0.00024960213,0.0005948354,0.0005425734,0.0006103093,0.0012269375,0.000009457702,0.00043905724,0.00024383701,0.00052750536],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006801591,0.0017662337,0.0026374971,0.044087026,0.0020438824,0.00017022429,0.00058389764,0.0027573914,0.022071412,0.057123452,0.1973798,0.66931117],"study_design_scores_gemma":[0.0003008682,0.00073649565,0.0001191674,0.0019670238,0.00020536898,0.00019555015,0.00007402382,0.00013432292,0.004471463,0.00025634863,0.9907842,0.000755152],"about_ca_topic_score_codex":0.000141456,"about_ca_topic_score_gemma":0.00008881181,"teacher_disagreement_score":0.7934044,"about_ca_system_score_codex":0.00006456846,"about_ca_system_score_gemma":0.0013383959,"threshold_uncertainty_score":0.9996503},"labels":[],"label_agreement":null},{"id":"W2902038937","doi":"10.1186/s13059-018-1586-y","title":"Applications and potential of genome editing in crop improvement","year":2018,"lang":"en","type":"review","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":427,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"Natural Science Foundation of Shandong Province; Institute of Genetics; National Natural Science Foundation of China","keywords":"Genome editing; Biology; Genome; Adaptation (eye); Computational biology; Genomics; Organism; Biotechnology; Gene; Genetics","score_opus":0.010328981996304384,"score_gpt":0.3256743241071773,"score_spread":0.3153453421108729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902038937","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006084179,0.9898298,0.008661657,0.000003958887,0.00012595215,0.0005079698,0.00013642512,0.0000049466835,0.00012090795],"genre_scores_gemma":[0.0034876368,0.99400127,0.0005862576,0.000012042666,0.00094349927,0.0001695648,0.0006965424,0.000028487319,0.00007470513],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988301,0.00003393358,0.00043115337,0.00042720741,0.000032044787,0.00024559267],"domain_scores_gemma":[0.9994337,0.0000068500153,0.00016153722,0.00031153037,0.000037267626,0.00004912094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015969516,0.00021540478,0.0005283073,0.00011322394,0.000027226239,0.0000057183206,0.00019830768,0.00034263855,0.000014549641],"category_scores_gemma":[0.000012354848,0.00019908832,0.000119464494,0.00008701054,0.00011340728,6.81726e-7,0.00024128711,0.0000985777,0.0000061375135],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007992746,0.00006049321,0.00002531025,0.0054819407,0.00024484296,0.0000021289654,0.000029427189,0.00002187549,0.1763883,0.00007474326,0.000028316033,0.81763464],"study_design_scores_gemma":[0.00012365278,0.000206019,0.000045004934,0.0000860142,0.000071470815,0.000017636026,0.000008564434,0.0000019206668,0.0002360748,0.000022076407,0.99899244,0.00018913976],"about_ca_topic_score_codex":0.000008839154,"about_ca_topic_score_gemma":0.000007986885,"teacher_disagreement_score":0.99896413,"about_ca_system_score_codex":0.000016339007,"about_ca_system_score_gemma":0.00006292048,"threshold_uncertainty_score":0.8118586},"labels":[],"label_agreement":null},{"id":"W2902080644","doi":"10.1097/cmr.0000000000000545","title":"Loss of miR-155 upregulates WEE1 in metastatic melanoma","year":2018,"lang":"en","type":"article","venue":"Melanoma Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute","keywords":"Wee1; Melanoma; Gene silencing; Cancer research; microRNA; Suppressor; Phenotype; Medicine; Metastasis; Metastatic melanoma; Population; Oncology; Cancer; Biology; Cell cycle; Internal medicine; Gene; Cyclin-dependent kinase 1; Genetics","score_opus":0.03179498572432186,"score_gpt":0.3865553176741381,"score_spread":0.3547603319498162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902080644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951284,0.0012762365,0.00059727684,0.00011592659,0.0000862301,0.00018981747,0.000011436813,0.0000060690513,0.0025886162],"genre_scores_gemma":[0.99755996,0.00006659736,0.0010799759,0.000009528759,0.00017804351,0.000024199575,0.000024979097,0.00002302411,0.0010336663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986061,0.0001316212,0.00024126198,0.000306561,0.0002830279,0.00043141755],"domain_scores_gemma":[0.9992332,0.00004674526,0.000026131975,0.00042993278,0.00018075193,0.00008324929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007708916,0.00011645211,0.0001728624,0.00017956553,0.00004822428,0.000015861837,0.00030044955,0.000091368456,0.00012449907],"category_scores_gemma":[0.00015310007,0.00010934066,0.000055593675,0.00030293057,0.0002624771,0.0000029841508,0.00019547268,0.0001389567,0.000047040434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017047484,0.00012110995,0.03658846,0.00009661498,0.00006887905,0.000034422625,0.0002956979,0.00007436555,0.95681,0.00026217336,0.0016374594,0.0038403303],"study_design_scores_gemma":[0.0006377847,0.00077528093,0.043263864,0.00003379864,0.0000058768005,0.000029465133,0.00018225452,0.00042180516,0.94188374,0.00027563842,0.012335483,0.00015498782],"about_ca_topic_score_codex":0.00011012039,"about_ca_topic_score_gemma":0.000257694,"teacher_disagreement_score":0.014926252,"about_ca_system_score_codex":0.000016479507,"about_ca_system_score_gemma":0.00007412844,"threshold_uncertainty_score":0.44587827},"labels":[],"label_agreement":null},{"id":"W2902250247","doi":"10.1101/485805","title":"Synthetic Biology Research and Innovation Profile 2018: Publications and Patents","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Office of Naval Research; National Key Research and Development Program of China; Japan Society for the Promotion of Science; Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Defense Advanced Research Projects Agency; National Institutes of Health; Directorate for Biological Sciences; National Natural Science Foundation of China; Natural Sciences and Engineering Research Council of Canada; U.S. Department of Energy; European Commission; Deutsche Forschungsgemeinschaft; National Science Foundation","keywords":"Synthetic biology; Citation; Subject (documents); Computer science; Library science; Data science; Biology; Computational biology","score_opus":0.03649711983264275,"score_gpt":0.32041935734286014,"score_spread":0.2839222375102174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902250247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99283415,0.001904674,0.003818265,0.00023213642,0.00043824452,0.0005227479,0.00015300285,0.000059278933,0.000037526308],"genre_scores_gemma":[0.9953279,0.00058992143,0.0032169246,0.000040219908,0.0004929733,0.00022592298,0.000005583774,0.000059797352,0.000040795385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982206,0.000082805294,0.0003033583,0.000860572,0.0001385605,0.0003941111],"domain_scores_gemma":[0.9981331,0.000021524924,0.000112680704,0.0008341884,0.00077442004,0.00012403897],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00073252036,0.0002577574,0.00020926322,0.0004353696,0.0001677845,0.00012760825,0.00024818088,0.0005172598,0.000015215495],"category_scores_gemma":[0.00038641918,0.00027466417,0.000025103322,0.00048910506,0.00032124322,0.0000062656627,0.0007694534,0.00034663192,0.000013216174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000118196,0.000046622074,0.009113008,0.0001379665,0.000060388764,7.0769414e-7,0.0000038603066,0.0000022486518,0.98837876,0.00080344634,0.001430021,0.000011122645],"study_design_scores_gemma":[0.00039668492,0.000301311,0.09011204,0.0001468624,0.000035911173,9.967879e-8,0.000004428817,0.00028417286,0.8646148,0.00003650112,0.043448366,0.0006188583],"about_ca_topic_score_codex":0.000015463018,"about_ca_topic_score_gemma":0.0000014363561,"teacher_disagreement_score":0.12376402,"about_ca_system_score_codex":0.000030498333,"about_ca_system_score_gemma":0.00018237236,"threshold_uncertainty_score":0.99997056},"labels":[],"label_agreement":null},{"id":"W2902868244","doi":"10.1071/rdv31n1ab20","title":"20 Generation of myostatin knockout horse embryos using clustered regularly interspaced short palindromic repeats/CRISPR-associated gene 9 and somatic cell nuclear transfer","year":2018,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artron Bioresearch (Canada)","funders":"","keywords":"Biology; CRISPR; Plasmid; Genetics; Molecular biology; Gene; Zinc finger nuclease; Guide RNA; Exon; Cas9; Genome editing","score_opus":0.026249552430097033,"score_gpt":0.27534239536700633,"score_spread":0.2490928429369093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902868244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788025,0.00038718185,0.020320188,0.000044859837,0.00015973719,0.00024646206,0.0000058184887,0.0000169188,0.000016318587],"genre_scores_gemma":[0.99349594,0.000055671826,0.006122852,0.000020114845,0.0000776931,0.0000060765133,0.000068446905,0.000018889234,0.00013433571],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987793,0.00006211104,0.00035879042,0.0005230195,0.00011505085,0.00016171136],"domain_scores_gemma":[0.99944556,0.0000034262473,0.000045577362,0.0003010226,0.00013625844,0.000068139925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033832015,0.00015385685,0.00017965015,0.000052944015,0.00013331627,0.000025200668,0.000047622907,0.000121745645,0.000011447946],"category_scores_gemma":[0.000059213275,0.00015968842,0.000031812506,0.000065850894,0.000081734106,0.000010228042,0.000058381404,0.00005855692,0.0000012111498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013324368,0.00006067097,0.0010342975,0.00006625963,0.000046322326,4.5726048e-7,0.001615022,0.00010539523,0.99385005,3.4450142e-7,0.00004897018,0.003038987],"study_design_scores_gemma":[0.00040676096,0.00015785739,0.026641073,0.000025407482,0.00003060395,0.000012953338,0.00036422978,0.002200887,0.96945477,0.000003685169,0.00052175694,0.00018003957],"about_ca_topic_score_codex":0.000017104547,"about_ca_topic_score_gemma":0.00004092675,"teacher_disagreement_score":0.025606776,"about_ca_system_score_codex":0.000031853127,"about_ca_system_score_gemma":0.000057546513,"threshold_uncertainty_score":0.6511905},"labels":[],"label_agreement":null},{"id":"W2903404198","doi":"10.1128/mbio.02321-18","title":"Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins","year":2018,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Government of Canada","keywords":"CRISPR; Cas9; Computational biology; Biology; Genome editing; Genetics; Gene","score_opus":0.0045243914265239715,"score_gpt":0.26025837679456,"score_spread":0.25573398536803604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903404198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980151,0.0007206958,0.0006263634,0.00012459,0.00009451645,0.00020303098,0.000025006524,0.00000770993,0.00018298543],"genre_scores_gemma":[0.998955,0.00029504817,0.00017589296,0.00013568974,0.00019331186,0.000011952258,0.000077586774,0.000013077609,0.000142459],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994102,0.000015895632,0.00011852004,0.00023879633,0.000050083654,0.00016650576],"domain_scores_gemma":[0.9997744,0.0000015251779,0.000020736876,0.00012746893,0.000021581494,0.000054292046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007792952,0.00010482948,0.00009486155,0.000023965644,0.000050309663,0.000021710306,0.000030178771,0.00009061814,0.000016493981],"category_scores_gemma":[0.000007934977,0.00010670686,0.0000156407,0.00003349781,0.00007029461,0.0000031306547,0.00007803377,0.000049898837,0.0000025969175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000102201475,0.000023574736,0.0005048508,0.000044595716,0.0000054477246,0.0000030540107,0.00004414881,5.990387e-7,0.9957311,0.000004163135,0.0030846864,0.0005435609],"study_design_scores_gemma":[0.0004920619,0.0002576101,0.0055845687,0.00004829937,0.0000066421003,0.000015712834,0.00002242297,0.000009190778,0.9812869,0.000010900376,0.012125497,0.00014018742],"about_ca_topic_score_codex":0.00008215812,"about_ca_topic_score_gemma":0.00011600551,"teacher_disagreement_score":0.014444192,"about_ca_system_score_codex":0.000005687205,"about_ca_system_score_gemma":0.000007773189,"threshold_uncertainty_score":0.43513796},"labels":[],"label_agreement":null},{"id":"W2903828136","doi":"10.20944/preprints201812.0117.v1","title":"Increasing Cellular Radioresistance by Simultaneous CRISPR/dCas9-Driven Overexpression of XPC and HR23B Genes","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Radioresistance; CRISPR; Gene; Biology; HEK 293 cells; Cas9; DNA damage; Clonogenic assay; Cell biology; Cell; Genetics; DNA; Cell culture","score_opus":0.024098661398269598,"score_gpt":0.3237785117460363,"score_spread":0.2996798503477667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903828136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861257,0.0068862843,0.005639975,0.00002441429,0.00024382577,0.0003819713,0.00015845131,0.000035333756,0.000504037],"genre_scores_gemma":[0.99500287,0.0020347976,0.001825139,0.000028106771,0.00032689664,0.0000294841,0.00028249325,0.00007012047,0.00040010997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977867,0.00012731612,0.00047854215,0.0010206047,0.00024248245,0.0003443589],"domain_scores_gemma":[0.9981993,0.00005474954,0.00027293395,0.0011422549,0.0001672055,0.00016357073],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003152791,0.00041867595,0.00044196192,0.000064254564,0.000083317806,0.000018854618,0.00045667728,0.00054339383,0.00007791559],"category_scores_gemma":[0.00032078841,0.0004504441,0.00015506422,0.000052630752,0.00018990779,0.0000039274373,0.0016254039,0.00030170375,0.000018398068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015446306,0.00005602734,0.05278138,0.00035411908,0.00011219478,0.000006318984,0.00012906414,0.0030147373,0.9427613,0.000002656596,0.00027067147,0.00035706194],"study_design_scores_gemma":[0.00035946077,0.00005473102,0.0049677375,0.00030668388,0.00006581836,0.000017537566,0.00003747917,0.0013039449,0.9793429,0.000049794497,0.013027677,0.0004662574],"about_ca_topic_score_codex":0.00012552786,"about_ca_topic_score_gemma":0.0000076413235,"teacher_disagreement_score":0.047813643,"about_ca_system_score_codex":0.000029550642,"about_ca_system_score_gemma":0.000072979434,"threshold_uncertainty_score":0.9997947},"labels":[],"label_agreement":null},{"id":"W2904045627","doi":"10.1016/j.trecan.2018.11.001","title":"A Road Map to Personalizing Targeted Cancer Therapies Using Synthetic Lethality","year":2018,"lang":"en","type":"review","venue":"Trends in cancer","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Health Research Foundation","keywords":"Synthetic lethality; CRISPR; Epigenetics; Computational biology; Personalized medicine; Precision medicine; Cancer; Biology; Medicine; Bioinformatics; Gene; Genetics; DNA repair","score_opus":0.07724367842033365,"score_gpt":0.4485675640002626,"score_spread":0.37132388557992896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2904045627","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013472011,0.9971076,0.00023737582,0.000050574094,0.00073944684,0.00019107222,0.00018340023,0.000016035307,0.00012729103],"genre_scores_gemma":[0.0012991051,0.9955512,0.0006232132,0.00007398664,0.0010269496,0.0002937395,0.000076072174,0.00009241169,0.00096329546],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99831355,0.00008588799,0.00036666414,0.0006540283,0.00015106647,0.00042880123],"domain_scores_gemma":[0.9992993,0.000009391795,0.00011170388,0.0004372761,0.000044553923,0.00009777643],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018128287,0.00042470125,0.0007344264,0.00015336575,0.000052102405,0.000027804512,0.0002910484,0.0003181844,0.00043385627],"category_scores_gemma":[0.000014292646,0.00038003657,0.00030135937,0.00032693188,0.000057811365,0.0000022603735,0.00012797868,0.00018865986,0.000007663376],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011175527,0.000020097532,0.0000383587,0.001647338,0.00020612033,0.0000033837998,0.00023621751,0.00025095404,0.0008544791,0.0000012259917,0.0010855844,0.99564505],"study_design_scores_gemma":[0.0001220622,0.000041694646,0.0000481812,0.0034645768,0.00018481411,0.0000066718853,0.000025343865,0.000052268224,0.0005163348,0.0000013543529,0.995044,0.0004927195],"about_ca_topic_score_codex":0.0011507969,"about_ca_topic_score_gemma":0.0012591004,"teacher_disagreement_score":0.99515235,"about_ca_system_score_codex":0.00019056324,"about_ca_system_score_gemma":0.00015982488,"threshold_uncertainty_score":0.9998652},"labels":[],"label_agreement":null},{"id":"W2904299237","doi":"10.18192/uojm.v8i2.3651","title":"Gene Therapy: A Promising Therapeutic Strategy for Malaria","year":2018,"lang":"en","type":"article","venue":"University of Ottawa Journal of Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Malaria; CRISPR; Cas9; Genome editing; Gene drive; Genetic enhancement; Medicine; Disease; Vector (molecular biology); Viral vector; Biology; Bioinformatics; Computational biology; Immunology; Gene; Genetics; Internal medicine","score_opus":0.01849907638238381,"score_gpt":0.28831628213919047,"score_spread":0.2698172057568067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2904299237","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8072993,0.0042835325,0.18586436,0.0011273536,0.00028027128,0.00016549602,0.000004957304,0.000003559994,0.00097114895],"genre_scores_gemma":[0.9958027,0.00034075422,0.0030503883,0.00006507473,0.00050172984,3.2795096e-8,0.000003349037,0.0000072518787,0.00022870049],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995754,0.00001779186,0.00013858994,0.00007665589,0.00009487693,0.000096681055],"domain_scores_gemma":[0.99943626,0.000012168176,0.00014281744,0.00009949723,0.00025494312,0.000054320873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027135195,0.00006766844,0.0001475057,0.000059940085,0.000042327647,0.000001899441,0.00015208732,0.000057664718,0.000055640463],"category_scores_gemma":[0.000026522626,0.000057924757,0.000066239234,0.000045075518,0.00014814758,0.0000031366596,0.000013574222,0.000047540034,3.2011988e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027950108,0.000035305256,0.000717726,0.00001818494,0.00017396019,0.0000056554272,0.0003057831,0.000110570894,0.9789001,0.00012420578,0.0024262334,0.016902795],"study_design_scores_gemma":[0.009666908,0.008812429,0.015424805,0.00014080603,0.00018005894,0.00020951097,0.0015933295,0.0003549437,0.7935112,0.0003109891,0.1695673,0.00022769537],"about_ca_topic_score_codex":0.00001024589,"about_ca_topic_score_gemma":0.000009401295,"teacher_disagreement_score":0.1885034,"about_ca_system_score_codex":0.000006981968,"about_ca_system_score_gemma":0.000057693207,"threshold_uncertainty_score":0.2362103},"labels":[],"label_agreement":null},{"id":"W2904791059","doi":"10.18192/uojm.v8i2.3741","title":"CRISPR-Cas9 Germline Editing: Full Steam Ahead to Revolutionary Profit or Revolutionary Public Medicine?","year":2018,"lang":"en","type":"article","venue":"University of Ottawa Journal of Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"CRISPR; Germline; Genome editing; Commercialization; Cas9; Intellectual property; Bioethics; Political science; Biology; Business; Genetics; Law","score_opus":0.017995124345456744,"score_gpt":0.2926866834287164,"score_spread":0.27469155908325965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2904791059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6212393,0.021194203,0.2608043,0.08026651,0.003723995,0.0007111771,0.000056269677,0.00004541614,0.011958828],"genre_scores_gemma":[0.98400396,0.0011749353,0.006505598,0.00047206657,0.0051844446,2.0439516e-7,0.000031539323,0.000021172727,0.0026060562],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860644,0.00006525755,0.00044358618,0.00021445053,0.0004193476,0.0002509014],"domain_scores_gemma":[0.9981096,0.000039522707,0.00032555184,0.000270864,0.00094520557,0.00030925745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073273253,0.00016397434,0.00036100097,0.00030210524,0.000118908705,0.0000011349733,0.0004030953,0.00012988945,0.0005789213],"category_scores_gemma":[0.00074573926,0.00013504183,0.000089341476,0.0002845166,0.00048669215,0.000014868442,0.00012024637,0.00017841805,0.000007873517],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059391354,0.000081415186,0.0035582918,0.000111138346,0.00019379568,0.00010951107,0.00052228145,0.00009580404,0.19817464,0.00018753552,0.7927004,0.003671247],"study_design_scores_gemma":[0.004281184,0.008453377,0.016823849,0.00074277096,0.00020415487,0.0011509332,0.0034697324,0.0001869081,0.0061406675,0.00007180858,0.9581878,0.0002868244],"about_ca_topic_score_codex":0.000041124225,"about_ca_topic_score_gemma":0.00009513202,"teacher_disagreement_score":0.3627647,"about_ca_system_score_codex":0.000054824897,"about_ca_system_score_gemma":0.00018447476,"threshold_uncertainty_score":0.63387823},"labels":[],"label_agreement":null},{"id":"W2906076582","doi":"10.1089/crispr.2018.0030","title":"Safe Harbor Targeted CRISPR-Cas9 Tools for Molecular-Genetic Imaging of Cells in Living Subjects","year":2018,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Robarts Clinical Trials; Western University","funders":"","keywords":"CRISPR; Cas9; Biology; Reporter gene; Plasmid; Gene; Genome editing; Green fluorescent protein; Molecular biology; Genetics; Gene expression","score_opus":0.008250713597200513,"score_gpt":0.2878417624945897,"score_spread":0.27959104889738917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906076582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8147185,0.003939484,0.1800223,0.0002186634,0.00052631303,0.00027302094,0.000015330397,0.000007598534,0.0002788311],"genre_scores_gemma":[0.9928973,0.000241193,0.0059348512,0.000228985,0.0005737499,0.0000147376895,0.0000033149147,0.00004464309,0.000061272636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860775,0.000093410104,0.0004336069,0.00024383515,0.00016917454,0.00045222064],"domain_scores_gemma":[0.9990902,0.00008420601,0.00015092606,0.00036199912,0.00021130712,0.000101392936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006122997,0.00020049697,0.0002124619,0.000098923076,0.00013061216,0.0000807516,0.00039685576,0.000084222076,0.00005229972],"category_scores_gemma":[0.00034856892,0.00016511527,0.00016749115,0.0001370729,0.000114637434,0.000010417111,0.0001129651,0.00019346834,0.0000049160735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006657105,0.000036084773,0.00087711803,0.000026237645,0.0000421909,0.000008544233,0.00023541087,0.0008419342,0.99335593,0.000019954228,0.0012751188,0.0032149097],"study_design_scores_gemma":[0.0005472117,0.00022982236,0.0070091314,0.00008833516,0.000044245775,0.00008455517,0.00025938297,0.0014293618,0.98651093,0.00010335157,0.0034718835,0.00022176025],"about_ca_topic_score_codex":0.000013506197,"about_ca_topic_score_gemma":0.000018525312,"teacher_disagreement_score":0.17817879,"about_ca_system_score_codex":0.000021562044,"about_ca_system_score_gemma":0.00009646121,"threshold_uncertainty_score":0.67332053},"labels":[],"label_agreement":null},{"id":"W2906117327","doi":"10.1089/crispr.2018.29037.kda","title":"The Phage Whisperer: An Interview with Sylvain Moineau","year":2018,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Computer science; Library science; Biology; Genetics; Gene","score_opus":0.011006069992096508,"score_gpt":0.31758288741777196,"score_spread":0.30657681742567544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906117327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83743244,0.011664999,0.14204827,0.004213546,0.0008733694,0.0002376484,0.0000053512335,0.000026349877,0.003498008],"genre_scores_gemma":[0.99556726,0.0009567855,0.0005061935,0.0005416256,0.0015549832,0.000005002756,0.0000029297598,0.000025828109,0.00083938224],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99917233,0.00011690927,0.000166632,0.000139475,0.0001357109,0.00026895193],"domain_scores_gemma":[0.9992786,0.0000142443405,0.00006164575,0.00042577987,0.0001190331,0.00010066389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072665757,0.00013080951,0.000085959444,0.000015520865,0.00047750253,0.00013096146,0.00046888075,0.000044655164,0.000061113395],"category_scores_gemma":[0.000034203873,0.00006185888,0.000062106476,0.00006336084,0.00017494363,0.0000050911303,0.000077033044,0.00020130663,0.000019724048],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065550156,0.00018738478,0.0010490135,0.000041364732,0.00065660145,0.000053238353,0.0027160991,0.00066509756,0.67767966,0.0007527084,0.09433483,0.22120853],"study_design_scores_gemma":[0.0008897864,0.0018898487,0.0022023872,0.000061648425,0.000087406086,0.0018864117,0.0014155834,0.0009993573,0.28863564,0.0002936519,0.7012918,0.00034650412],"about_ca_topic_score_codex":0.000004049682,"about_ca_topic_score_gemma":0.00008767731,"teacher_disagreement_score":0.60695696,"about_ca_system_score_codex":0.000009211772,"about_ca_system_score_gemma":0.000041879728,"threshold_uncertainty_score":0.36726117},"labels":[],"label_agreement":null},{"id":"W2906279666","doi":"","title":"Medicinal marijuana: Commercialisation and innovation in a complex regulatory environment","year":2018,"lang":"en","type":"article","venue":"Australasian biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Legislation; Project commissioning; Competition (biology); Business; Face (sociological concept); State (computer science); Production (economics); Publishing; International trade; Industrial organization; Marketing; Economics; Political science; Law; Ecology","score_opus":0.016910660784537408,"score_gpt":0.29293394549381757,"score_spread":0.27602328470928017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906279666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895804,0.000107964646,0.0075092656,0.0023276627,0.000060859114,0.00011936682,0.0000039754486,0.000020551071,0.0002699354],"genre_scores_gemma":[0.9979219,0.00008610807,0.0015533167,0.00015123107,0.00011667009,0.000007471875,0.000069774454,0.000009515334,0.00008400346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935937,0.0000139955055,0.00018456184,0.0002247901,0.0000524298,0.0001648596],"domain_scores_gemma":[0.9997167,0.0000024121853,0.000040481667,0.00020679549,0.000012573257,0.000021040545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098796314,0.00009391279,0.00009455251,0.00020744947,0.0000343241,0.0000048591023,0.00007908451,0.00026838036,0.00003231011],"category_scores_gemma":[0.000022314292,0.00010170408,0.000010232995,0.00019082651,0.00028922415,0.0000021018247,0.00006925987,0.00009227384,0.000006287187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019836263,0.00002322699,0.009928638,0.000008587367,0.0000129104055,0.0000023802734,0.000048664133,0.0000113710685,0.94807994,0.003805205,0.0012993065,0.036759906],"study_design_scores_gemma":[0.0008625431,0.0006129581,0.41817275,0.000012080523,0.000012060485,0.000063465355,0.0002129604,0.00023145368,0.47398934,0.0006398898,0.10494847,0.00024204682],"about_ca_topic_score_codex":0.00001621647,"about_ca_topic_score_gemma":0.000053978016,"teacher_disagreement_score":0.47409064,"about_ca_system_score_codex":0.000015474283,"about_ca_system_score_gemma":0.000010272959,"threshold_uncertainty_score":0.4147372},"labels":[],"label_agreement":null},{"id":"W2906621567","doi":"10.1089/crispr.2018.0045","title":"Double-Stranded Biotinylated Donor Enhances Homology-Directed Repair in Combination with Cas9 Monoavidin in Mammalian Cells","year":2018,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Biotinylation; Homology (biology); CRISPR; Biology; Homology directed repair; Cell biology; Chemistry; Computational biology; Molecular biology; Genetics; DNA; DNA repair; Gene; Nucleotide excision repair","score_opus":0.009366188521981598,"score_gpt":0.28263483309608345,"score_spread":0.2732686445741018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906621567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966835,0.0005593081,0.0016288827,0.0004361035,0.00024877983,0.00018604838,0.000003391349,0.000023385357,0.00023060695],"genre_scores_gemma":[0.99841803,0.00023548084,0.00081227464,0.00007774578,0.00019478975,0.000007992609,0.000008791786,0.000018557681,0.00022632525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989938,0.00009936255,0.00028593754,0.00021225454,0.00010550437,0.00030312277],"domain_scores_gemma":[0.99953103,0.000013837073,0.00008738414,0.00021229527,0.00009323723,0.00006221351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004842197,0.000152888,0.00015352134,0.00011265987,0.00009774773,0.000027849424,0.00020133285,0.0001263204,0.000037048274],"category_scores_gemma":[0.000016697295,0.00010853609,0.00005321712,0.00023118082,0.00011412545,0.000006983797,0.00003410177,0.00026500243,0.000006064219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009105534,0.000121760684,0.0041213566,0.000014352769,0.00005153286,0.000049965474,0.00064047467,0.0006424934,0.9905089,0.000012802995,0.0020181935,0.00090760813],"study_design_scores_gemma":[0.0029751332,0.0006377741,0.01583185,0.000046748828,0.00001966714,0.00023732537,0.000241795,0.0006667979,0.97643745,0.000057855395,0.0026510458,0.00019655074],"about_ca_topic_score_codex":0.00014616999,"about_ca_topic_score_gemma":0.0013088428,"teacher_disagreement_score":0.014071451,"about_ca_system_score_codex":0.000027819708,"about_ca_system_score_gemma":0.000057575493,"threshold_uncertainty_score":0.44259733},"labels":[],"label_agreement":null},{"id":"W2906792477","doi":"10.1016/j.scr.2018.101372","title":"Fibroblast-derived integration-free iPSC line ISRM-NBS1 from an 18-year-old Nijmegen Breakage Syndrome patient carrying the homozygous NBN c.657_661del5 mutation","year":2018,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf","keywords":"Biology; Induced pluripotent stem cell; LIN28; SOX2; Homeobox protein NANOG; Embryoid body; Embryonic stem cell; Mutation; Cell culture; Molecular biology; KLF4; Reprogramming; Cell biology; Genetics; Cell; Gene","score_opus":0.025482729061142486,"score_gpt":0.33860767773914563,"score_spread":0.31312494867800317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906792477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99188906,0.0005068301,0.005121267,0.00015307797,0.0001674727,0.00049663766,0.00009885283,0.000030240635,0.0015365757],"genre_scores_gemma":[0.9971368,0.00006229636,0.0007101435,0.00006031599,0.00043925716,0.00006472733,0.00030343217,0.00005486385,0.0011682184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978648,0.0002592574,0.00030610952,0.0005415994,0.0005108301,0.00051742245],"domain_scores_gemma":[0.9982053,0.000110788,0.00006042155,0.0010467896,0.00040302763,0.0001736944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005072692,0.00021068666,0.00016566331,0.00010063269,0.00034397037,0.00013704746,0.0005903315,0.00018893625,0.00013746804],"category_scores_gemma":[0.00008562529,0.00016937121,0.00008451376,0.00024593683,0.00018953136,0.000012896402,0.0003781378,0.0003204141,0.00007425051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000118609154,0.00007555382,0.00011588152,0.0000334085,0.00004845789,0.000045319943,0.0015690678,0.0007214415,0.9856854,0.00001415499,0.00276481,0.008807893],"study_design_scores_gemma":[0.00073024543,0.0018271233,0.0013510416,0.00007796587,0.000015554193,0.000054836728,0.0030269718,0.0034698087,0.98674786,0.00013941574,0.0022641567,0.00029503598],"about_ca_topic_score_codex":0.0006007119,"about_ca_topic_score_gemma":0.0007827205,"teacher_disagreement_score":0.008512857,"about_ca_system_score_codex":0.00004718559,"about_ca_system_score_gemma":0.000102284364,"threshold_uncertainty_score":0.69067574},"labels":[],"label_agreement":null},{"id":"W2907742760","doi":"10.20944/preprints201811.0444.v1","title":"TALEN Mediated Gene Targeting for CF Gene Therapy","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Hospital for Sick Children","funders":"Peking University; Cystic Fibrosis Canada; Canadian Institutes of Health Research; Cystic Fibrosis Foundation Therapeutics","keywords":"Transcription activator-like effector nuclease; Genome editing; Biology; Genetic enhancement; Reporter gene; Gene targeting; Minigene; Gene; Gene delivery; Gene expression; Nuclease; Viral vector; Genetics; Molecular biology; Computational biology; Cell biology; Exon; CRISPR; Recombinant DNA","score_opus":0.05691900137962026,"score_gpt":0.3640255360927087,"score_spread":0.30710653471308846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2907742760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97771734,0.0030890205,0.016150836,0.00011534385,0.0010992712,0.0009748113,0.00017000627,0.00009111531,0.00059228344],"genre_scores_gemma":[0.98783886,0.002516184,0.0043620877,0.00018248316,0.002002658,0.00042053455,0.0018029764,0.0001280455,0.00074613857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975434,0.000059568785,0.00049038837,0.0011880108,0.00020009509,0.0005185679],"domain_scores_gemma":[0.9981445,0.000028681296,0.0002101705,0.0011940097,0.0002572303,0.00016538054],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059937907,0.00046625902,0.00038655484,0.00007790526,0.000106737316,0.000022481061,0.00068398204,0.0006461678,0.0002003485],"category_scores_gemma":[0.00031865222,0.0004895267,0.00032823562,0.00006312673,0.00009011847,0.000002598242,0.0012069134,0.00030304538,0.00014055408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011244026,0.000063942185,0.018903727,0.000090440866,0.00027546583,0.0000022119893,0.00015146901,0.0012595386,0.9779567,0.0000024986055,0.00075425813,0.00042727086],"study_design_scores_gemma":[0.00065617415,0.00007856298,0.011990049,0.000028695295,0.00003329423,0.000005880476,0.000018266663,0.00037920556,0.93330276,0.00013261726,0.05283801,0.0005364812],"about_ca_topic_score_codex":0.000030101479,"about_ca_topic_score_gemma":0.0000057491357,"teacher_disagreement_score":0.052083753,"about_ca_system_score_codex":0.000033898967,"about_ca_system_score_gemma":0.00014503667,"threshold_uncertainty_score":0.9997556},"labels":[],"label_agreement":null},{"id":"W2907895283","doi":"10.3390/genes10010017","title":"Alternative Biochemistries for Alien Life: Basic Concepts and Requirements for the Design of a Robust Biocontainment System in Genetic Isolation","year":2018,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Genetic code; Synthetic biology; Organism; Biology; Isolation (microbiology); Computer science; Computational biology; Genetics; Gene; Bioinformatics","score_opus":0.06040738796236684,"score_gpt":0.36494767866756467,"score_spread":0.30454029070519784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2907895283","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029352214,0.7140164,0.28376752,0.0000033377341,0.00012790937,0.0016866012,0.00009889601,0.0000032269402,0.0000026399991],"genre_scores_gemma":[0.0059503596,0.9862493,0.0059908633,0.000008713216,0.00040619096,0.0011537265,0.00014882562,0.00004126292,0.00005072169],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989202,0.000039605966,0.0004157541,0.00035746727,0.000076471544,0.00019047642],"domain_scores_gemma":[0.9992996,0.00008896133,0.00022393899,0.00026344316,0.00008485413,0.000039193656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028316394,0.00024185551,0.00044684546,0.00004350087,0.000052083764,0.000017972707,0.00019068131,0.0001699323,9.3915156e-7],"category_scores_gemma":[0.00006610337,0.00018081418,0.0001332913,0.000056198973,0.000078779245,0.0000016535947,0.000074072974,0.000028830707,2.6942718e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041841742,0.00011832335,0.00014256118,0.06374328,0.002326049,0.0000019333936,0.00046037394,0.010306022,0.03982703,0.0001256627,0.0020567428,0.8804736],"study_design_scores_gemma":[0.0023402371,0.0013647763,0.000037817943,0.0056177685,0.0014738172,0.000026313122,0.0005270285,0.009934806,0.10765286,0.000031490188,0.8699666,0.0010264786],"about_ca_topic_score_codex":0.000011292175,"about_ca_topic_score_gemma":0.000005538284,"teacher_disagreement_score":0.8794471,"about_ca_system_score_codex":0.000030960364,"about_ca_system_score_gemma":0.00010986579,"threshold_uncertainty_score":0.73733884},"labels":[],"label_agreement":null},{"id":"W2907976376","doi":"10.1007/978-1-4939-8991-1_21","title":"Gene Replacement by Intron Targeting with CRISPR-Cas9","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Genome editing; Cas9; Gene; Intron; Biology; Genetics; Computational biology; Homology directed repair; Genome; Gene knockout; DNA; Gene targeting; Homology (biology); Homologous recombination; DNA repair; Nucleotide excision repair","score_opus":0.00591489628406061,"score_gpt":0.3773505685823677,"score_spread":0.3714356722983071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2907976376","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.27946272,0.0023998104,0.71710765,0.00007758111,0.00017008689,0.00023842324,0.000006006479,0.00001318436,0.00052451575],"genre_scores_gemma":[0.2485985,0.00013541234,0.75005203,0.00043643956,0.000072688235,0.000057352983,0.00020098715,0.00005120593,0.00039537845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982838,0.00033952235,0.00027975067,0.0006033727,0.00007251627,0.0004210493],"domain_scores_gemma":[0.999316,0.00002776514,0.00006989415,0.0004784399,0.000040709554,0.000067229725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007538623,0.00022895486,0.00025923934,0.00007260024,0.00002430692,0.000011268931,0.0002167839,0.00022095052,0.000056943416],"category_scores_gemma":[0.00010875185,0.00020471335,0.00006437706,0.00013266123,0.0000539286,0.0000017611286,0.00015182137,0.00017018671,0.000009500072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097217446,0.000029794259,0.0058043725,0.000016205815,0.000047265527,0.0000042286706,0.00002259336,0.00085840677,0.9895363,0.000076908145,0.00032003582,0.0031866773],"study_design_scores_gemma":[0.00077012856,0.0006396492,0.00013369623,0.0000085276315,0.000011495336,0.000016930095,0.00004987076,0.00030679966,0.9615344,0.00009083547,0.036155768,0.0002819059],"about_ca_topic_score_codex":0.000024825475,"about_ca_topic_score_gemma":0.0000045809365,"teacher_disagreement_score":0.035835735,"about_ca_system_score_codex":0.000024086356,"about_ca_system_score_gemma":0.000031852207,"threshold_uncertainty_score":0.8347968},"labels":[],"label_agreement":null},{"id":"W2908238701","doi":"10.1007/978-1-4939-8991-1_24","title":"Biolistic Delivery of CRISPR/Cas9 with Ribonucleoprotein Complex in Wheat","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Ribonucleoprotein; Cas9; Genome editing; Subgenomic mRNA; Biology; Genome; Computational biology; Genome engineering; DNA; Genetics; Gene; RNA","score_opus":0.014951989416616086,"score_gpt":0.3974300456125697,"score_spread":0.38247805619595365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2908238701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5797276,0.0008863902,0.41849235,0.000032647647,0.000069313006,0.0002602303,0.000007864134,0.000005724191,0.0005178874],"genre_scores_gemma":[0.68941855,0.000055566088,0.31027982,0.0001017782,0.000017822467,0.000022401284,0.000041682837,0.000023897948,0.00003847532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845695,0.0003567478,0.00033575812,0.00045004633,0.00006189264,0.00033860045],"domain_scores_gemma":[0.99932486,0.000042953354,0.000069036636,0.0004655176,0.000050503662,0.000047147856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051968655,0.00020284066,0.00036487106,0.00018217933,0.000009957522,0.000004786022,0.00023248863,0.00022950552,0.000041267274],"category_scores_gemma":[0.000090166075,0.00018504103,0.0000709851,0.00023861634,0.00010731288,0.0000017656185,0.00013472585,0.00015159235,0.0000041807048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010990454,0.000046296413,0.018415816,0.00005075806,0.000025821748,0.000010226276,0.000025496662,0.0019386683,0.97513944,0.00033985346,0.000007701141,0.0038900482],"study_design_scores_gemma":[0.0011589393,0.0006202069,0.010205595,0.000043338896,0.00001103831,0.00002076739,0.00006419473,0.0009216268,0.9836817,0.00035816574,0.0026251425,0.0002893115],"about_ca_topic_score_codex":0.00016168336,"about_ca_topic_score_gemma":0.00010104192,"teacher_disagreement_score":0.10969098,"about_ca_system_score_codex":0.000017533926,"about_ca_system_score_gemma":0.00004966447,"threshold_uncertainty_score":0.75457543},"labels":[],"label_agreement":null},{"id":"W2909308595","doi":"10.1016/j.dmpk.2018.09.039","title":"Genome-guided medications for safer and more effective treatment of disease","year":2019,"lang":"en","type":"article","venue":"Drug Metabolism and Pharmacokinetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"SAFER; Disease; Medicine; Intensive care medicine; Genome; Computational biology; Pharmacology; Biology; Internal medicine; Genetics; Computer science; Gene; Computer security","score_opus":0.006939475469778332,"score_gpt":0.31528675579884313,"score_spread":0.3083472803290648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909308595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97590005,0.020312373,0.002553078,0.00016550365,0.00014910032,0.00064603466,0.00018709392,0.0000055223154,0.00008121499],"genre_scores_gemma":[0.99240357,0.0059528644,0.00072470016,0.00006801562,0.00019021277,0.00008067326,0.00014003747,0.000016637496,0.00042326536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994749,0.000016554499,0.00012602696,0.0002050164,0.000057339956,0.00012017808],"domain_scores_gemma":[0.99961597,0.000025063304,0.000034730263,0.00015389387,0.00004869938,0.000121624995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055801273,0.00012227605,0.0001549334,0.0000334302,0.000026671594,0.000006300391,0.00004702325,0.00003083427,0.000011284143],"category_scores_gemma":[0.000008138281,0.00010544623,0.000049307135,0.000035964695,0.00004829728,0.0000019425531,0.000029899827,0.000019035677,6.693511e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001627675,0.000104415136,0.0032766766,0.00018392877,0.00026350498,4.4893932e-7,0.0005692042,0.00069296604,0.9801465,0.00016354954,0.00021455162,0.014221451],"study_design_scores_gemma":[0.004670512,0.00019691655,0.16229784,0.00001288059,0.0008222421,0.0000044294356,0.0001066093,0.0022806833,0.52459925,0.0001028093,0.3045611,0.00034473502],"about_ca_topic_score_codex":0.0000046497535,"about_ca_topic_score_gemma":5.82195e-7,"teacher_disagreement_score":0.4555473,"about_ca_system_score_codex":0.0000025812474,"about_ca_system_score_gemma":0.000016814833,"threshold_uncertainty_score":0.42999724},"labels":[],"label_agreement":null},{"id":"W2909954685","doi":"10.3390/genes10010039","title":"TALEN-Mediated Gene Targeting for Cystic Fibrosis-Gene Therapy","year":2019,"lang":"en","type":"article","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"Peking University; Cystic Fibrosis Canada; Canadian Institutes of Health Research; Cystic Fibrosis Foundation Therapeutics","keywords":"Transcription activator-like effector nuclease; Biology; Genome editing; Genetic enhancement; Cystic fibrosis; Gene targeting; Cystic fibrosis transmembrane conductance regulator; Minigene; Reporter gene; Gene delivery; Gene; Nuclease; Gene expression; Molecular biology; Cell biology; Genetics; CRISPR; Exon","score_opus":0.0059958239275220175,"score_gpt":0.26077087787535247,"score_spread":0.25477505394783045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909954685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96511185,0.014401008,0.01944558,0.000043919328,0.00044971373,0.00036656985,0.000068780966,0.000029352548,0.00008324741],"genre_scores_gemma":[0.98806494,0.000996719,0.008771652,0.00014512142,0.0005458501,0.00006465212,0.00061725837,0.000047389556,0.0007464362],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991287,0.000015065198,0.0001667329,0.00031838682,0.000081423204,0.00028971088],"domain_scores_gemma":[0.9995413,0.000023398361,0.00004116393,0.00026908284,0.00006131555,0.00006376474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012029241,0.0001609837,0.0001389629,0.000030532512,0.00005043516,0.000018708883,0.0001469642,0.0001183883,0.0000394063],"category_scores_gemma":[0.000035816225,0.00015240323,0.00010426311,0.000058188558,0.000017006781,0.00000209414,0.00004696335,0.00003497166,0.000037145674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060790266,0.000016317024,0.0011173458,0.000024637557,0.00003994013,4.5162963e-7,0.00002738632,0.0017998526,0.9929229,0.0000033178253,0.000799568,0.0031874734],"study_design_scores_gemma":[0.000663634,0.0002224654,0.0010306292,0.000004596528,0.0000074915665,0.000004954353,0.000027878628,0.0005884903,0.90216506,0.000013355872,0.095063634,0.00020781411],"about_ca_topic_score_codex":0.000005098405,"about_ca_topic_score_gemma":0.0000020288815,"teacher_disagreement_score":0.09426406,"about_ca_system_score_codex":0.0000062434033,"about_ca_system_score_gemma":0.000030489891,"threshold_uncertainty_score":0.6214823},"labels":[],"label_agreement":null},{"id":"W2910618698","doi":"10.1002/jgc4.1073","title":"Indigenous Peoples and genomics: Starting a conversation","year":2018,"lang":"en","type":"article","venue":"Journal of Genetic Counseling","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia; B.C. Women's Hospital & Health Centre; Children's & Women's Health Centre of British Columbia","funders":"Genome British Columbia","keywords":"Indigenous; Conversation; Thematic analysis; Interpretation (philosophy); Focus group; Racism; Theme (computing); Sociology; Public relations; Qualitative research; Gender studies; Political science; Social science; Linguistics; World Wide Web; Anthropology; Biology; Communication; Computer science","score_opus":0.004923944645650424,"score_gpt":0.25886724598541316,"score_spread":0.25394330133976273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910618698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9296481,0.0056880293,0.06432164,0.00003917152,0.000219081,0.000055703284,0.0000013693979,0.0000029056457,0.000024013889],"genre_scores_gemma":[0.9873824,0.00217504,0.0094292965,0.000100602905,0.00087487616,6.953227e-7,0.0000013458244,0.000014859787,0.00002088033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999307,0.000017970375,0.00030111973,0.00011235861,0.00011156172,0.00015000485],"domain_scores_gemma":[0.99944216,0.000016962647,0.00016189773,0.00010100372,0.00020702566,0.00007094571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002812029,0.00008836671,0.00011309574,0.0000588938,0.00006864924,0.000030776406,0.000084162195,0.00005867598,0.000009713318],"category_scores_gemma":[0.00007579632,0.00008661338,0.000043844964,0.000041831103,0.000044916866,0.0000030872911,0.000025559413,0.00006180674,0.0000019848778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007119904,0.000014874735,0.006701925,0.000028953778,0.000069482136,0.000005983097,0.007066891,0.001136755,0.96716577,0.0000013039627,0.00019258645,0.017544296],"study_design_scores_gemma":[0.00349869,0.004116459,0.049946718,0.0002360322,0.00030374213,0.0014512992,0.011969287,0.006722246,0.87772375,0.0004874043,0.042548306,0.000996091],"about_ca_topic_score_codex":0.0000067630963,"about_ca_topic_score_gemma":0.00003317875,"teacher_disagreement_score":0.08944202,"about_ca_system_score_codex":0.000013285073,"about_ca_system_score_gemma":0.00011720393,"threshold_uncertainty_score":0.3531991},"labels":[],"label_agreement":null},{"id":"W2911024257","doi":"10.3166/i2m.17.653-661","title":"Comparing gene regulatory inferring algorithms with different perspective","year":2018,"lang":"en","type":"article","venue":"Instrumentation Mesure Métrologie","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Perspective (graphical); Algorithm; Computational biology; Computer science; Biology; Artificial intelligence","score_opus":0.018232229263305283,"score_gpt":0.3172559338284476,"score_spread":0.29902370456514227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911024257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93854123,0.00016658466,0.059974868,0.00009356155,0.00020639313,0.00015178164,0.0000051667926,0.000043781598,0.0008166105],"genre_scores_gemma":[0.9947892,0.000026447826,0.004536679,0.000115003124,0.0003710852,0.000024821218,0.000049068225,0.000021015823,0.00006669682],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991008,0.000036697347,0.0001516575,0.0003275121,0.000147505,0.0002358311],"domain_scores_gemma":[0.9995045,0.000006876122,0.000057593283,0.0002525549,0.00011468422,0.000063763924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102567654,0.00016855373,0.00013714886,0.00005335003,0.00010189865,0.000028770497,0.00012535695,0.00008548882,0.00001798071],"category_scores_gemma":[0.00002179745,0.0001426569,0.00004329677,0.000069285656,0.000118088195,0.0000063100356,0.0000713813,0.00008119348,0.0000057949665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029492818,0.0000743474,0.12030432,0.000012415595,0.0002293052,0.0000056570716,0.00058942544,0.0018631753,0.8686478,0.000355686,0.0003035719,0.0073193326],"study_design_scores_gemma":[0.0010510143,0.00062363484,0.25646996,0.000010779791,0.000029626792,0.000024201423,0.0004738871,0.00089895923,0.73974633,0.000098949335,0.000352581,0.00022006521],"about_ca_topic_score_codex":0.00002088031,"about_ca_topic_score_gemma":0.00007603935,"teacher_disagreement_score":0.13616565,"about_ca_system_score_codex":0.00004897347,"about_ca_system_score_gemma":0.000029792367,"threshold_uncertainty_score":0.58173794},"labels":[],"label_agreement":null},{"id":"W2911506501","doi":"10.1503/cmaj.181657","title":"“CRISPR babies”: What does this mean for science and Canada?","year":2019,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"McGill University; McGill Genome Centre; McGill University Health Centre","funders":"","keywords":"CRISPR; Palindrome; Key (lock); China; Biology; Genetics; Computer science; History; Gene; Ecology; Archaeology","score_opus":0.00237011338153704,"score_gpt":0.23216746473030475,"score_spread":0.22979735134876772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911506501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97915655,0.0011206305,0.00046096352,0.015553096,0.0025272472,0.00017336095,0.000025892818,0.0000036567412,0.0009786156],"genre_scores_gemma":[0.99283767,0.00042516738,0.00015983752,0.0048016687,0.0007301943,0.0000036002532,0.000006602403,0.000009556343,0.0010257044],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988193,0.0000151085405,0.00013594913,0.00014704661,0.00055904785,0.0003235564],"domain_scores_gemma":[0.998791,0.000025974052,0.000047034817,0.00007933846,0.00033879568,0.00071790547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009803359,0.000067232446,0.000082446386,0.00004925023,0.00016542972,0.00012308716,0.00015904309,0.000120131124,0.0002362348],"category_scores_gemma":[0.0008213692,0.00005555822,0.000024476774,0.000058278703,0.00003238331,0.000011613998,0.000019262825,0.00014782658,0.0000029222965],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040058534,0.000029570276,0.14938214,0.00010861151,0.00033257884,0.00006396881,0.0010987323,0.00011785069,0.070797846,0.00079597323,0.59831107,0.17892164],"study_design_scores_gemma":[0.00044817818,0.00005329421,0.004458804,0.000026802838,0.000008351804,0.000073517906,0.0008198686,0.0003735253,0.008018965,0.000028474518,0.98554295,0.00014727209],"about_ca_topic_score_codex":0.07304068,"about_ca_topic_score_gemma":0.8935251,"teacher_disagreement_score":0.8204844,"about_ca_system_score_codex":0.00029566593,"about_ca_system_score_gemma":0.004727511,"threshold_uncertainty_score":0.93313205},"labels":[],"label_agreement":null},{"id":"W2911720118","doi":"10.1182/blood-2018-99-120229","title":"Comprehensive Integrated Genomic Perturbations Reveal Molecular Mechanisms of Red Blood Cell Trait Associations","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Biology; Genetics; Genome-wide association study; Single-nucleotide polymorphism; Chromatin; Gene; Computational biology; Genotype","score_opus":0.007157463926986183,"score_gpt":0.24437593890513581,"score_spread":0.23721847497814963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911720118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9706633,0.00040297245,0.027102703,0.000055656037,0.00009251095,0.00016621116,0.00013837276,0.000019282214,0.0013589666],"genre_scores_gemma":[0.9899976,0.000023508883,0.009184024,0.00009189528,0.00009743501,0.00001256794,0.00024564238,0.000024794548,0.00032252326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992449,0.000034418797,0.0002181601,0.00022955476,0.00009316125,0.0001797967],"domain_scores_gemma":[0.99937356,0.000010333735,0.00008006426,0.00026588596,0.00021180545,0.00005836092],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005517594,0.00013172292,0.00014729277,0.00004673922,0.000059582268,0.000010153206,0.00014808649,0.00013327957,0.000027243363],"category_scores_gemma":[0.00004069332,0.00013952282,0.00010000974,0.000112895614,0.000043601554,0.0000017034577,0.00005263062,0.00006828791,0.000004848788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000049833257,0.00020914132,0.00008959711,0.000011646146,0.00013152423,0.0000017053477,0.00006637211,0.00007224023,0.99896663,0.00013589393,0.00026118144,0.000049094644],"study_design_scores_gemma":[0.0010061467,0.0003525025,0.0041831816,0.000007606392,0.000171758,0.000009166811,0.000078570825,0.0000578598,0.99245256,0.00022080963,0.0013063622,0.00015347793],"about_ca_topic_score_codex":0.000018631688,"about_ca_topic_score_gemma":0.000010892609,"teacher_disagreement_score":0.019334285,"about_ca_system_score_codex":0.000005724363,"about_ca_system_score_gemma":0.00005629566,"threshold_uncertainty_score":0.5689575},"labels":[],"label_agreement":null},{"id":"W2911838180","doi":"10.1128/msphere.00002-19","title":"A CRISPR Interference Platform for Efficient Genetic Repression in <i>Candida albicans</i>","year":2019,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Banting Research Foundation; University of Guelph","keywords":"CRISPR; CRISPR interference; Biology; Candida albicans; Cas9; Psychological repression; Virulence; Gene; RNA interference; Repressor; Genetics; Pathogen; Genetic screen; Trans-activating crRNA; Corpus albicans; Fungal pathogen; Human pathogen; Computational biology; RNA; Gene expression; Mutant","score_opus":0.00633170988995219,"score_gpt":0.2769470367006662,"score_spread":0.27061532681071404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911838180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96594,0.0009893095,0.03060491,0.000028768487,0.00022937237,0.00036513348,0.000009812978,0.000011272792,0.0018213971],"genre_scores_gemma":[0.9969133,0.000042339856,0.0016821394,0.00008960486,0.00007353865,0.000052633197,0.000023675646,0.000021082811,0.0011016489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991948,0.000007709819,0.00017038896,0.00032421338,0.00006720921,0.00023567396],"domain_scores_gemma":[0.9995577,0.000012451043,0.000031091648,0.00032170615,0.00002637743,0.000050692597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007032904,0.00012313704,0.00012198447,0.000020033118,0.000019874784,0.000014614245,0.00015115038,0.00010002098,0.00009824175],"category_scores_gemma":[0.000025492916,0.00011433619,0.000060680068,0.00005826543,0.000014048149,0.0000013344252,0.00007799251,0.00006481242,0.000016758047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021519014,0.000083108716,0.014318331,0.00012377213,0.000023439723,0.000003391023,0.00023839972,0.04696622,0.91898245,0.000040595438,0.0022040645,0.016801035],"study_design_scores_gemma":[0.0038031596,0.0010505874,0.034777638,0.0002880569,0.000027230753,0.000031031643,0.000597785,0.028474862,0.83472145,0.0001430054,0.095214956,0.00087026175],"about_ca_topic_score_codex":0.000030329116,"about_ca_topic_score_gemma":0.00009001584,"teacher_disagreement_score":0.093010895,"about_ca_system_score_codex":0.000014404451,"about_ca_system_score_gemma":0.00002898787,"threshold_uncertainty_score":0.46624944},"labels":[],"label_agreement":null},{"id":"W2911938510","doi":"10.1101/552208","title":"Paralog dependency indirectly affects the robustness of human cells","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"","keywords":"Biology; Robustness (evolution); Gene; Genetics; CRISPR; Function (biology); Loss function; Gene duplication; Phenotype; Computational biology","score_opus":0.00860877359597686,"score_gpt":0.2447618813704281,"score_spread":0.23615310777445123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911938510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98952657,0.00259592,0.0056275628,0.000028477209,0.0013585693,0.0006898382,0.0000955435,0.000052455303,0.000025079562],"genre_scores_gemma":[0.99817276,0.00028716857,0.00075526605,0.000039614715,0.0005283052,0.00008608481,0.0000012095845,0.00010770107,0.000021884762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807763,0.00010947646,0.00036367224,0.00074427977,0.0002677056,0.0004372364],"domain_scores_gemma":[0.99774575,0.000026773412,0.00029880152,0.0016144867,0.00019801714,0.00011615079],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004242109,0.00046128928,0.00044591556,0.000103044265,0.00009551687,0.000060811268,0.00079515827,0.0006131206,0.000017561784],"category_scores_gemma":[0.000058674108,0.00041248967,0.00022178101,0.00017136884,0.00010558627,0.0000040880273,0.0006322992,0.00047441307,0.0000118759035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012049542,0.00005499968,0.0019609262,0.00036687768,0.00014384525,0.0000044967005,0.000005021959,0.013818543,0.9831318,0.000034007986,0.00046572104,0.0000016953084],"study_design_scores_gemma":[0.0003012659,0.00010224443,0.015173936,0.00014120869,0.00009235458,2.2433078e-8,0.0000028431584,0.0003497423,0.9821402,5.1304136e-7,0.0012033965,0.0004922759],"about_ca_topic_score_codex":0.000022018417,"about_ca_topic_score_gemma":0.0000064993537,"teacher_disagreement_score":0.013468801,"about_ca_system_score_codex":0.000033076856,"about_ca_system_score_gemma":0.00025050793,"threshold_uncertainty_score":0.9998327},"labels":[],"label_agreement":null},{"id":"W2912317070","doi":"10.1016/j.jgg.2019.01.001","title":"The 10th National Congress of Genetic Society of China: Celebrating its 40th anniversary in Nanjing","year":2018,"lang":"en","type":"article","venue":"Journal of genetics and genomics/Journal of Genetics and Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Jiangsu Collaborative Innovation Center for Modern Crop Production; State Key Laboratory of Crop Genetics and Germplasm Enhancement; Nanjing Agricultural University; Canada's Michael Smith Genome Sciences Centre","keywords":"Piwi-interacting RNA; Germline; Biology; Genetics; Gene knockdown; RNA interference; Gene; RNA; Molecular biology","score_opus":0.0077631673052185116,"score_gpt":0.2642494063528429,"score_spread":0.25648623904762435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912317070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9503393,0.046032794,0.0027667042,0.00016045808,0.00047230732,0.00013880756,0.00003150617,8.028227e-7,0.000057329355],"genre_scores_gemma":[0.9360284,0.046495676,0.016589694,0.00006397847,0.0007441986,5.7125675e-7,0.0000021950025,0.000037798407,0.000037460697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975302,0.00006916382,0.0014900931,0.00022145979,0.00036104015,0.00032803786],"domain_scores_gemma":[0.9970132,0.00006468749,0.001455382,0.00020870092,0.001075965,0.00018205728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010786492,0.00027470384,0.0005242732,0.00017005634,0.00015466144,0.000058203397,0.000440948,0.00020419544,0.0000037830123],"category_scores_gemma":[0.00007594714,0.00023320441,0.00025373383,0.0001451356,0.00032650487,0.000013023864,0.00023033202,0.00028774393,1.7720797e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000279365,0.00009955621,0.009771173,0.00013555902,0.00043587154,0.000008833827,0.0015888206,0.018091502,0.95849466,0.00004544447,0.0006260621,0.010423172],"study_design_scores_gemma":[0.00560366,0.0056045987,0.15265396,0.0003328058,0.00039278594,0.0015043411,0.0026193669,0.021985514,0.7804841,0.0013256187,0.026595453,0.0008977899],"about_ca_topic_score_codex":0.000005409715,"about_ca_topic_score_gemma":0.000026513899,"teacher_disagreement_score":0.17801054,"about_ca_system_score_codex":0.000051046994,"about_ca_system_score_gemma":0.00049053447,"threshold_uncertainty_score":0.95097995},"labels":[],"label_agreement":null},{"id":"W2912459593","doi":"10.1007/s10539-018-9659-6","title":"Mutationism, not Lamarckism, captures the novelty of CRISPR–Cas","year":2019,"lang":"en","type":"article","venue":"Biology & Philosophy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Novelty; Philosophy of biology; Inheritance (genetic algorithm); Mechanism (biology); Computer science; Cognitive science; Computational biology; Biology; Epistemology; Philosophy; Genetics; Psychology; Philosophy of science; Gene","score_opus":0.01040039887359077,"score_gpt":0.3025565396182401,"score_spread":0.2921561407446493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912459593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879308,0.0013851621,0.0040565445,0.0016723056,0.0005273167,0.00027150026,0.000054373497,0.000016799018,0.0040852],"genre_scores_gemma":[0.99806565,0.00007154971,0.00029945406,0.0008722051,0.00039852492,0.000014053786,0.000091624606,0.000017289078,0.00016962813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992556,0.000040393355,0.00019451034,0.0002622839,0.00006556085,0.00018164786],"domain_scores_gemma":[0.9993966,0.000031773616,0.000071052666,0.00040618447,0.00006481878,0.000029568688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012290446,0.00013887977,0.00015449639,0.00003360071,0.00004344723,0.0000060132606,0.00024147068,0.00016919081,0.000038207796],"category_scores_gemma":[0.000038684666,0.000100896366,0.00011170115,0.000054454893,0.0001259582,0.0000016924553,0.00009677487,0.00009579682,0.00003201175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000519846,0.00003183186,0.00649767,0.000025924648,0.000083928804,7.7083826e-7,0.00008735222,0.0003738319,0.9844233,0.0072194603,0.00064941694,0.0005545326],"study_design_scores_gemma":[0.00067910523,0.00042755154,0.026994957,0.0000121885,0.000032344113,0.000023442868,0.000045529083,0.00010585868,0.92949605,0.0036953744,0.0382266,0.0002610125],"about_ca_topic_score_codex":0.00002329623,"about_ca_topic_score_gemma":0.00000672747,"teacher_disagreement_score":0.05492726,"about_ca_system_score_codex":0.0000050735666,"about_ca_system_score_gemma":0.000030243678,"threshold_uncertainty_score":0.41144344},"labels":[],"label_agreement":null},{"id":"W2913124665","doi":"10.1038/s41467-019-08777-y","title":"Precise tuning of gene expression levels in mammalian cells","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Royal Society; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; National Institute for Health and Care Research; Cancer Research UK; International Seafood Sustainability Foundation; Wellcome Trust","keywords":"Gene silencing; microRNA; CRISPR; Computational biology; Biology; Gene; Gene expression; Regulation of gene expression; Cas9; RNA interference; Endogeny; Cell biology; Genetics; RNA","score_opus":0.012537566075429997,"score_gpt":0.31377327907517755,"score_spread":0.30123571299974755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913124665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866959,0.008388669,0.0016519814,0.00013969633,0.00014150547,0.00020834668,0.000026217012,0.000008187162,0.0027395196],"genre_scores_gemma":[0.9811748,0.00020183793,0.018248476,0.000029381934,0.000018125002,0.000008826727,0.00006277868,0.000010636502,0.00024510172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956214,0.000035740937,0.0001365888,0.00011690817,0.000057406378,0.00009123154],"domain_scores_gemma":[0.99881727,0.000020702282,0.000039922383,0.0010548662,0.000042688942,0.00002457354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001021304,0.000065376,0.000080843456,0.000044901248,0.000020850388,0.000004390956,0.00044840443,0.00018242658,0.000014766907],"category_scores_gemma":[0.000027559476,0.000066761604,0.000036508434,0.00008816976,0.0000212449,0.0000022421982,0.0001848286,0.00021560189,0.0000048836005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004706325,0.000028122688,0.0029226523,0.00000884779,0.000003919613,8.809215e-8,0.00006895472,0.00053567823,0.9957738,0.000049117705,0.00022799897,0.00037610452],"study_design_scores_gemma":[0.00020656068,0.000023369153,0.011672154,0.000026931384,0.0000030196252,0.0000011895858,0.000052515195,0.00022870296,0.97168076,0.000009757789,0.016018385,0.000076670076],"about_ca_topic_score_codex":0.0000060970888,"about_ca_topic_score_gemma":0.0000530611,"teacher_disagreement_score":0.024093064,"about_ca_system_score_codex":0.000006457634,"about_ca_system_score_gemma":0.000020813668,"threshold_uncertainty_score":0.2722459},"labels":[],"label_agreement":null},{"id":"W2913239114","doi":"10.1038/s41562-019-0544-3","title":"Questioning the proposed translational pathway for germline genome editing","year":2019,"lang":"en","type":"article","venue":"Nature Human Behaviour","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Genome editing; Germline; CRISPR; Genome; Genetics; Biology; World Wide Web; Computational biology; Computer science; Gene","score_opus":0.00584225822660125,"score_gpt":0.3005624991676628,"score_spread":0.2947202409410616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913239114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914086,0.0008606972,0.0063536293,0.00022164543,0.0003403214,0.0004765127,0.00004621309,0.00002169885,0.00027066976],"genre_scores_gemma":[0.9963048,0.000002797154,0.0010897708,0.00010983357,0.0009246681,0.00002416664,0.0004809035,0.000024721256,0.0010383439],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935544,0.000013247751,0.00013335519,0.00021947574,0.00011058465,0.00016788195],"domain_scores_gemma":[0.9996463,0.0000106947155,0.000040523133,0.00019109547,0.000081505306,0.000029892799],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017545623,0.000109333705,0.0000784521,0.000022804827,0.00013295769,0.000025046666,0.00014002612,0.00021139075,0.000034195713],"category_scores_gemma":[0.000022414293,0.00008666003,0.00008851765,0.000034613466,0.000018390592,0.0000025689535,0.000021438529,0.00022478783,0.0000032365745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012785939,0.000024061623,0.0076500317,0.000023543205,0.00001666992,6.1040504e-7,0.00007982869,0.0009697142,0.98962694,0.000930468,0.0001805192,0.00048482322],"study_design_scores_gemma":[0.00290182,0.0006431117,0.31834507,0.00007247904,0.000113466696,0.000039787003,0.0001904116,0.0008054695,0.5806437,0.0005255442,0.09485254,0.0008665734],"about_ca_topic_score_codex":0.0000021510452,"about_ca_topic_score_gemma":0.000013311897,"teacher_disagreement_score":0.4089832,"about_ca_system_score_codex":0.0000068253826,"about_ca_system_score_gemma":0.000025513662,"threshold_uncertainty_score":0.35338935},"labels":[],"label_agreement":null},{"id":"W2913828593","doi":"10.1101/553214","title":"De novo mutations across 1,465 diverse genomes reveal novel mutational insights and reductions in the Amish founder population","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Genetics; Biology; Heritability; Mutation rate; Population; Genetic variation; Genome; Loss of heterozygosity; Founder effect; Evolutionary biology; Gene; Genotype; Haplotype; Allele; Demography","score_opus":0.013378784359254145,"score_gpt":0.27427262571964117,"score_spread":0.260893841360387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913828593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987423,0.0012688368,0.010076993,0.00014796418,0.00042590377,0.00044088214,0.00018319189,0.000026866424,0.00000634556],"genre_scores_gemma":[0.9952541,0.00017149208,0.003898289,0.00012460245,0.0003812126,0.000103414626,0.000012538306,0.00004230623,0.00001202703],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99866945,0.00005500002,0.00027873833,0.00053110294,0.0001725424,0.00029319758],"domain_scores_gemma":[0.9991307,0.000028044911,0.00011967849,0.0004993689,0.00014758135,0.00007461855],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025998705,0.0002558983,0.00018342481,0.000093687064,0.0001650172,0.00014934535,0.00022966212,0.0003219526,0.000004328998],"category_scores_gemma":[0.00009046923,0.00025489577,0.00007226993,0.00017710046,0.000077424775,0.000011981151,0.000208357,0.0003068576,0.0000037140433],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022634564,0.00012946856,0.030562462,0.00016930744,0.00012917926,0.00001311361,0.00023821356,0.022289779,0.94596183,0.00038200803,0.000091400674,0.000010607595],"study_design_scores_gemma":[0.0007983833,0.000047564277,0.9645942,0.00009763804,0.000077823825,7.78966e-7,0.00013255737,0.0011669134,0.029893572,0.000016664122,0.002591462,0.00058244466],"about_ca_topic_score_codex":0.000071219954,"about_ca_topic_score_gemma":0.000036578876,"teacher_disagreement_score":0.9340317,"about_ca_system_score_codex":0.00008361954,"about_ca_system_score_gemma":0.0001835947,"threshold_uncertainty_score":0.99999034},"labels":[],"label_agreement":null},{"id":"W2914186588","doi":"10.1016/j.ymgme.2018.12.264","title":"Lentiviral-modified T Rapa cells as 'micropharmacies' for lysosomal diseases","year":2019,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Progenitor cell; Haematopoiesis; Genetic enhancement; Ex vivo; Biology; CD34; Stem cell; Immunology; Cancer research; Population; Cell biology; Medicine; In vitro; Biochemistry","score_opus":0.0047114185796601335,"score_gpt":0.2705744805641876,"score_spread":0.26586306198452747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914186588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9502305,0.025560088,0.022192596,0.00006045181,0.00050342083,0.00057187193,0.00007047182,0.000017582788,0.00079305883],"genre_scores_gemma":[0.9948663,0.0014300552,0.0016970423,0.00054036104,0.00024959896,0.000052115192,0.000098555734,0.00006029082,0.0010056554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987886,0.000029013343,0.00020189611,0.0004943913,0.00011930592,0.00036681982],"domain_scores_gemma":[0.9993052,0.00000898361,0.000051395127,0.00038848704,0.00008183383,0.0001641391],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000076338234,0.0002569219,0.00023953777,0.00006029435,0.00006217162,0.00006211708,0.00017512403,0.00012235362,0.000016998632],"category_scores_gemma":[0.000014734085,0.00026191171,0.00018090942,0.000066828055,0.00005069031,0.000003246272,0.00014193125,0.000063471925,0.000014713308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052804542,0.000036981946,0.000088310764,0.00005084282,0.000089304034,0.0000032300431,0.000025361462,0.0010858892,0.9947934,0.0007067758,0.00038565468,0.0026814523],"study_design_scores_gemma":[0.0013290592,0.00010750791,0.0005461058,0.0000053729746,0.00011482884,0.000007947858,0.000019818406,0.0006699676,0.8310593,0.0003822424,0.16544005,0.00031780807],"about_ca_topic_score_codex":0.000004321388,"about_ca_topic_score_gemma":5.9143264e-7,"teacher_disagreement_score":0.1650544,"about_ca_system_score_codex":0.000003582649,"about_ca_system_score_gemma":0.000046901496,"threshold_uncertainty_score":0.9999833},"labels":[],"label_agreement":null},{"id":"W2914434989","doi":"10.1139/bcb-2018-0353","title":"Cellular roles of the human Obg-like ATPase 1 (hOLA1) and its YchF homologs","year":2019,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Ministero dello Sviluppo Economico","keywords":"GTPase; Biology; Carcinogenesis; Translation (biology); Function (biology); Computational biology; Cell biology; Motility; Signal transduction; Protein family; Genetics; Messenger RNA; Cancer; Gene","score_opus":0.014055363184345759,"score_gpt":0.30416036348092973,"score_spread":0.290105000296584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914434989","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07982009,0.9189248,0.000022080707,0.0000058355586,0.00017408202,0.0002690448,0.00014285017,0.0000075085322,0.00063367194],"genre_scores_gemma":[0.1013124,0.8949266,0.00001995514,0.00002473852,0.00020179145,0.000025722047,0.00040952247,0.00003563181,0.003043645],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99853987,0.00008073528,0.00039607345,0.00063520373,0.000057272453,0.00029084462],"domain_scores_gemma":[0.9990911,0.000025873249,0.00017791736,0.0005765058,0.000039566312,0.00008901906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014033052,0.0004189863,0.0007292493,0.000030500676,0.00008476665,0.000011636351,0.00036454046,0.0009026722,0.000015026495],"category_scores_gemma":[0.000023959474,0.00030447863,0.00026767352,0.00007106037,0.00019929952,0.0000012594768,0.00044602787,0.00025390022,0.0000034381344],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062258796,0.000042597727,0.00005275331,0.009254087,0.000115841875,0.0000021233263,0.000012953877,0.0000011375337,0.95510745,0.000043040534,0.00017077093,0.03519101],"study_design_scores_gemma":[0.00019756686,0.00008919226,0.0000036729764,0.00035646994,0.00024564264,0.000033185515,0.000014317651,0.0000021043475,0.41820747,0.000005049891,0.5805431,0.00030226517],"about_ca_topic_score_codex":0.0000027498672,"about_ca_topic_score_gemma":0.0000013957942,"teacher_disagreement_score":0.58037233,"about_ca_system_score_codex":0.000008302993,"about_ca_system_score_gemma":0.00008979811,"threshold_uncertainty_score":0.99994075},"labels":[],"label_agreement":null},{"id":"W2915013877","doi":"10.1038/s41587-018-0011-0","title":"Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing","year":2019,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":724,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Human Genome Research Institute; Nature","keywords":"Genome editing; CRISPR; Ribonucleoprotein; Computational biology; Biology; Epigenetics; Multiplex; Gene; Cas9; Genetics; HEK 293 cells; RNA","score_opus":0.001938441349481033,"score_gpt":0.22484331994718187,"score_spread":0.22290487859770083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2915013877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9701059,0.008296117,0.020441977,0.00034122655,0.00020428935,0.00046810825,0.000054076558,0.000062125626,0.000026185551],"genre_scores_gemma":[0.9786828,0.0003887872,0.020389242,0.00011601198,0.00021779588,0.000040518164,0.00006771684,0.000042022628,0.000055105873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896467,0.000015582102,0.00013787861,0.000493352,0.000060374823,0.000328124],"domain_scores_gemma":[0.99952084,0.000045267916,0.000059483333,0.00026600884,0.00004504304,0.00006338013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001474936,0.00022536621,0.00022415495,0.00010629955,0.000068024085,0.000022758812,0.00011175339,0.0008438009,0.0000038132162],"category_scores_gemma":[0.00016054022,0.00020203863,0.00003282322,0.00008082666,0.00007953567,0.0000053027065,0.00010368836,0.00029884168,3.547714e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097522105,0.000011951035,0.0006834751,0.000096068354,0.00006141803,0.0000022519596,0.000020416652,0.00003317798,0.99605507,0.00008206718,0.000101863785,0.0027547125],"study_design_scores_gemma":[0.001332127,0.000499003,0.0014078896,0.000021925236,0.000037371115,0.000058682603,0.00018399383,0.0017959282,0.9893417,0.000027823577,0.005020046,0.0002735198],"about_ca_topic_score_codex":0.000011729312,"about_ca_topic_score_gemma":0.00001836186,"teacher_disagreement_score":0.008576905,"about_ca_system_score_codex":0.000007595178,"about_ca_system_score_gemma":0.000028474286,"threshold_uncertainty_score":0.8238896},"labels":[],"label_agreement":null},{"id":"W2915674805","doi":"10.1504/ijarge.2018.10019321","title":"Top plant breeding techniques for improving food security: an expert Delphi survey of the opportunities and challenges","year":2018,"lang":"en","type":"article","venue":"International Journal of Agricultural Resources Governance and Ecology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Food security; Delphi method; Delphi; Agriculture; Business; Population; Sustainable agriculture; Biotechnology; Environmental resource management; Natural resource economics; Environmental planning; Computer science; Geography; Biology; Economics; Ecology; Environmental health; Medicine","score_opus":0.02966336104516624,"score_gpt":0.27992154261374325,"score_spread":0.250258181568577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2915674805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99416107,0.0045544985,0.00007318487,0.00081837876,0.00023632938,0.00005451025,0.000053588934,0.0000018394979,0.00004659402],"genre_scores_gemma":[0.99209243,0.007055167,0.00021245293,0.00008417509,0.0005231036,0.0000030446124,0.000006019733,0.0000040976174,0.000019525032],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995096,0.000023740611,0.00018488121,0.000095255564,0.00009881714,0.000087714],"domain_scores_gemma":[0.99935997,0.000036214802,0.00022206087,0.00004610167,0.000301828,0.00003383335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039404,0.000072998664,0.00010789113,0.000016169995,0.00004126595,0.000017905635,0.00018728066,0.000068072215,0.0000017618698],"category_scores_gemma":[0.00012102621,0.000044206277,0.00003608981,0.00001335844,0.00008319096,0.000013510354,0.00009388295,0.00004647263,1.4453837e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013426056,0.00020574138,0.032548837,0.00016236897,0.00081491686,0.000008283046,0.00926311,0.00004211617,0.7939693,0.002025299,0.0031236366,0.15649384],"study_design_scores_gemma":[0.00061526196,0.0036595967,0.76568586,0.000081561266,0.000023294637,0.00052531436,0.0026744953,0.00007402017,0.19316015,0.00008203099,0.033228725,0.00018970862],"about_ca_topic_score_codex":0.00004339285,"about_ca_topic_score_gemma":0.00092757563,"teacher_disagreement_score":0.733137,"about_ca_system_score_codex":0.000009553619,"about_ca_system_score_gemma":0.000016067717,"threshold_uncertainty_score":0.18026797},"labels":[],"label_agreement":null},{"id":"W2917855738","doi":"10.1126/science.aaw7166","title":"Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice","year":2019,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":684,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Key Research and Development Program of China; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Genome; Biology; Computational biology; Genetics; Gene","score_opus":0.006153930249904703,"score_gpt":0.26497167233576724,"score_spread":0.25881774208586256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917855738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954199,0.00027178245,0.0021254474,0.00016654239,0.0008948369,0.00013421182,0.000012120095,0.000010270037,0.00096484734],"genre_scores_gemma":[0.99675876,0.000020906227,0.0020866105,0.00017102521,0.00038853992,0.000010038619,0.000018967681,0.000009473729,0.0005356807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990042,0.000010868869,0.00013854075,0.00036275873,0.00019841913,0.00028520357],"domain_scores_gemma":[0.99950063,0.00001677038,0.000030390896,0.00029512102,0.000067825844,0.000089262714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002556281,0.000098206816,0.00008101584,0.000110579895,0.00005718491,0.000029543615,0.0003080322,0.00005817016,0.000025023044],"category_scores_gemma":[0.00020110222,0.00009907137,0.000029317136,0.0004109221,0.0001047793,0.0000109758275,0.000106662075,0.000086642365,0.000047380716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000052610058,0.000015673804,0.0068123764,0.0000071334885,0.0000017690669,0.0000018430226,0.000057448797,0.004012803,0.98877096,0.000005775249,0.00016081546,0.00014811465],"study_design_scores_gemma":[0.0002519719,0.000071592,0.17774081,0.0000071253526,0.0000027087558,0.0000056132953,0.00012045592,0.0009152673,0.8101054,0.0000136964645,0.010594371,0.00017101137],"about_ca_topic_score_codex":0.000017961574,"about_ca_topic_score_gemma":0.000009996669,"teacher_disagreement_score":0.17866562,"about_ca_system_score_codex":0.000021939202,"about_ca_system_score_gemma":0.00016551552,"threshold_uncertainty_score":0.4040013},"labels":[],"label_agreement":null},{"id":"W2917873126","doi":"10.1089/crispr.2018.0052","title":"Meet the Anti-CRISPRs: Widespread Protein Inhibitors of CRISPR-Cas Systems","year":2019,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Horizontal gene transfer; Mobile genetic elements; Biology; Plasmid; Transposable element; Trans-activating crRNA; Gene; Genetics; Genome editing; Computational biology; Bacteria; Genome; Bacterial conjugation","score_opus":0.03198250993016277,"score_gpt":0.3633563609090158,"score_spread":0.331373850978853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917873126","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004178989,0.99062455,0.0048805284,0.00012172035,0.0020354548,0.001435902,0.000054816523,0.000013822514,0.00041530945],"genre_scores_gemma":[0.012656134,0.98401105,0.000076138705,0.00003459585,0.0021634777,0.0000822864,0.000025813844,0.00013672742,0.0008137801],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966662,0.00057610305,0.001239045,0.00043619005,0.0005028995,0.00057959807],"domain_scores_gemma":[0.99729013,0.00011788781,0.0009373068,0.0012794951,0.00023108294,0.00014406329],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001590661,0.00064364675,0.0013381632,0.00013668058,0.00026290677,0.00018385037,0.0014202608,0.00047927143,0.000021621185],"category_scores_gemma":[0.00025093366,0.00033808633,0.0009819359,0.00025843544,0.00019268261,0.000008044592,0.00034744953,0.0009260086,0.000034919256],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022893964,0.0006237186,0.00008896312,0.075225875,0.00888326,0.00017263215,0.00153529,0.0048390985,0.07292168,0.0018122116,0.27934435,0.554324],"study_design_scores_gemma":[0.00026709205,0.00020231325,0.000003562553,0.0058721313,0.00093365734,0.0011118132,0.00023108422,0.000024748515,0.01516911,0.000024338646,0.9757041,0.0004560519],"about_ca_topic_score_codex":0.000033800174,"about_ca_topic_score_gemma":0.000005279578,"teacher_disagreement_score":0.69635975,"about_ca_system_score_codex":0.000051407635,"about_ca_system_score_gemma":0.00040715782,"threshold_uncertainty_score":0.99990714},"labels":[],"label_agreement":null},{"id":"W2918043289","doi":"10.1016/j.rsci.2018.11.001","title":"Improvements of TKC Technology Accelerate Isolation of Transgene-Free CRISPR/Cas9-Edited Rice Plants","year":2019,"lang":"en","type":"article","venue":"Rice Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Transgenic Science and Technology Program; Ministry of Agriculture of the People's Republic of China; Consejo de Ciencia y Tecnología del Estado de Tabasco; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Biology; CRISPR; Transgene; Cas9; Genome editing; Genetics; Gene; Genetically modified rice; Genetically modified crops; Computational biology; Biotechnology","score_opus":0.006751623861124935,"score_gpt":0.2834103016454121,"score_spread":0.27665867778428715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918043289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850967,0.00026206215,0.013434567,0.0000470666,0.00023137864,0.00016312936,0.000023801347,0.00001005128,0.00073128054],"genre_scores_gemma":[0.99752486,0.00006909589,0.002220556,0.000028375307,0.00002762782,0.0000042744355,0.000007877762,0.0000075587404,0.00010978988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906206,0.0000072072153,0.00020964474,0.00029330002,0.00020602379,0.00022177384],"domain_scores_gemma":[0.99925834,0.000007204506,0.0000983372,0.00045845925,0.00013637368,0.000041314026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021440096,0.00009607619,0.00012479463,0.00015857875,0.000035395882,0.0000075855028,0.0005224632,0.00009047228,0.0000114723325],"category_scores_gemma":[0.000058048063,0.0000922637,0.00003379821,0.00048523923,0.00013282118,0.000010350755,0.0001255243,0.000055974684,0.0000043326063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018443425,0.000027287813,0.0016785575,0.00004207581,0.000008363028,1.7891553e-7,0.000046654237,0.00046306194,0.9969071,0.00002389204,0.00006007398,0.0007242894],"study_design_scores_gemma":[0.00042217885,0.0002340159,0.010259451,0.000013371567,0.000006675232,0.0000028264815,0.000091286296,0.001296402,0.9872921,0.000043086267,0.00023776921,0.00010079822],"about_ca_topic_score_codex":0.0000192142,"about_ca_topic_score_gemma":0.0000053136087,"teacher_disagreement_score":0.01242818,"about_ca_system_score_codex":0.000009111179,"about_ca_system_score_gemma":0.000074155345,"threshold_uncertainty_score":0.37624043},"labels":[],"label_agreement":null},{"id":"W2918227673","doi":"10.1038/s41598-019-38718-0","title":"Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Office of AIDS Research; National Institute of Allergy and Infectious Diseases; Vlaamse regering; International AIDS Society; University of California, San Francisco; Center for AIDS Research, University of Washington; Canadian Institutes of Health Research; KU Leuven; Fonds Wetenschappelijk Onderzoek","keywords":"Provirus; Integrase; Biology; Gene; Chromatin; CRISPR; Genome editing; Locus (genetics); Cell cycle; Cell; Viral replication; Cell culture; Virology; Genetics; Cell biology; Computational biology; Genome","score_opus":0.004654174546564984,"score_gpt":0.23316800757176862,"score_spread":0.22851383302520364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918227673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898981,0.00013801511,0.0016108563,0.000016927863,0.006686143,0.0003631865,0.0000021231058,0.0000148872,0.0012697744],"genre_scores_gemma":[0.9972397,0.0000061679953,0.0003246151,0.000012771919,0.00018757429,0.000011252243,0.000033282467,0.000013772487,0.0021708282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886733,0.000025068952,0.0002843205,0.00041181425,0.00021108656,0.00020034805],"domain_scores_gemma":[0.9990175,0.000003854048,0.0001978699,0.0006306453,0.00010735897,0.000042785396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005414614,0.000104952254,0.00010344792,0.000049890612,0.00011635852,0.000043423956,0.000099633515,0.000081848455,0.000019575727],"category_scores_gemma":[0.00009811726,0.00008423337,0.00010691098,0.0002064508,0.00006405631,0.0000049060254,0.00012116234,0.000079229874,0.0000073733045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000017366614,0.000012967674,0.006500525,0.000035789402,0.000010175487,0.0000030695194,0.00005361989,0.006429796,0.98529166,0.0000012832413,0.0013404653,0.0003189221],"study_design_scores_gemma":[0.000077919016,0.000018093622,0.001763221,0.000031191452,0.000005803366,0.000024365032,0.000020921098,0.00037558487,0.9812829,0.000027120706,0.016276233,0.000096633055],"about_ca_topic_score_codex":0.0000069203334,"about_ca_topic_score_gemma":0.000006644523,"teacher_disagreement_score":0.014935767,"about_ca_system_score_codex":0.000012491209,"about_ca_system_score_gemma":0.00006893061,"threshold_uncertainty_score":0.3434937},"labels":[],"label_agreement":null},{"id":"W2918797603","doi":"10.1007/s11248-019-00118-5","title":"Benefits of genome-edited crops: expert opinion","year":2019,"lang":"en","type":"article","venue":"Transgenic Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canada First Research Excellence Fund","keywords":"Biology; Agriculture; Expert opinion; Biotechnology; Genome; European union; Genome editing; Product (mathematics); Variety (cybernetics); Business; Genetics; International trade; Gene; Ecology; Computer science","score_opus":0.044397937943458365,"score_gpt":0.3970377277231525,"score_spread":0.3526397897796941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918797603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98718834,0.008399945,0.0017668443,0.00010329783,0.00018314208,0.0002821162,0.000015553416,0.000008690603,0.0020520694],"genre_scores_gemma":[0.99542296,0.0031931796,0.00030555078,0.000015136388,0.000233379,0.00001713686,0.00006587215,0.00002352651,0.0007232606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888146,0.000051987547,0.00017233641,0.0002738564,0.00029959666,0.00032077415],"domain_scores_gemma":[0.9993276,0.000019915014,0.0000143881225,0.00041757294,0.0001444209,0.000076123804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039052338,0.00009260908,0.00012080983,0.00009273304,0.000032079133,0.000009831985,0.00026304412,0.00011928434,0.00017498479],"category_scores_gemma":[0.000022320464,0.000089099376,0.000082017665,0.0001839506,0.000055970668,0.0000021735932,0.000053436113,0.00013210528,0.000044624107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074677824,0.000036498033,0.00052670896,0.000053328084,0.00003353101,1.4188072e-7,0.00020691754,0.002200611,0.99377364,0.00006829368,0.0003980119,0.0026276228],"study_design_scores_gemma":[0.00084629725,0.0005769814,0.020021725,0.00003057387,0.0000021414025,0.0000040505975,0.00016451113,0.00015747992,0.9092987,0.000017329969,0.06869848,0.00018170953],"about_ca_topic_score_codex":0.000038896273,"about_ca_topic_score_gemma":0.000009366135,"teacher_disagreement_score":0.084474936,"about_ca_system_score_codex":0.000008762211,"about_ca_system_score_gemma":0.000052898158,"threshold_uncertainty_score":0.3633367},"labels":[],"label_agreement":null},{"id":"W2921207188","doi":"10.1080/14756366.2019.1587416","title":"CRISPR/Cas9-based liver-derived reporter cells for screening of mPGES-1 inhibitors","year":2019,"lang":"en","type":"article","venue":"Journal of Enzyme Inhibition and Medicinal Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Education and Child Care","funders":"Medical Innovation Project of Fujian Province; Natural Science Foundation of Fujian Province","keywords":"Flow cytometry; CRISPR; Cas9; Inflammation; Reporter gene; Immunofluorescence; High-throughput screening; Fluorescence; Molecular biology; Biology; Chemistry; Cancer research; Cell biology; Biochemistry; Gene; Gene expression; Immunology; Antibody","score_opus":0.0086909725005621,"score_gpt":0.27311677117291394,"score_spread":0.26442579867235183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921207188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96580666,0.0014735963,0.03205014,0.00012793734,0.00017681092,0.00012232148,0.000010879649,0.0000036554818,0.00022798554],"genre_scores_gemma":[0.99659663,0.00012059421,0.0024121827,0.00013753638,0.0004937283,0.0000029387957,0.000025151916,0.000016433385,0.00019482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990083,0.000011599272,0.00047331754,0.00016142098,0.00019706777,0.00014829228],"domain_scores_gemma":[0.9991115,0.000031774187,0.00035920934,0.00013469816,0.00023505698,0.00012776513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033212508,0.00013416394,0.00024113758,0.000044195018,0.000024343564,0.0000086044865,0.000057288074,0.00013956403,0.00004895684],"category_scores_gemma":[0.000096844065,0.000120362776,0.00015301132,0.000043941323,0.000057861977,0.00000646326,0.000022972135,0.00012054414,2.8533967e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021640798,0.000037015176,0.00025761378,0.00033659377,0.00003395189,0.000014335966,0.000037117465,0.00029607376,0.9957943,9.0057335e-7,0.002241851,0.00073385844],"study_design_scores_gemma":[0.001638038,0.00046324148,0.00016902981,0.00031199877,0.000054970285,0.00020282192,0.00026889873,0.00027207666,0.9905004,0.0000058877795,0.00598823,0.00012440032],"about_ca_topic_score_codex":0.0000023467994,"about_ca_topic_score_gemma":5.9915595e-7,"teacher_disagreement_score":0.030789942,"about_ca_system_score_codex":0.000010000653,"about_ca_system_score_gemma":0.00007855333,"threshold_uncertainty_score":0.49082515},"labels":[],"label_agreement":null},{"id":"W2921219680","doi":"10.1016/j.ymthe.2019.03.003","title":"Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"Sangamo Therapeutics","keywords":"Zinc finger nuclease; Genome editing; Transgene; Biology; Zinc finger; Gene; Gene delivery; Genetic enhancement; In vivo; Genome; Messenger RNA; Gene knockout; Computational biology; Cell biology; Genetics","score_opus":0.004535572124586177,"score_gpt":0.22677664807937314,"score_spread":0.22224107595478695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921219680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886901,0.0063680355,0.004293617,0.000018735282,0.00014524885,0.0003113377,0.00002158543,0.000007479337,0.00014390604],"genre_scores_gemma":[0.9984247,0.0003015028,0.00094373646,0.0001250311,0.000066265784,0.000012062941,0.000028099406,0.000044219803,0.000054385207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888235,0.0000363638,0.0003146103,0.00031148628,0.00017017961,0.0002850059],"domain_scores_gemma":[0.9993671,0.000012151935,0.00010558129,0.0003928805,0.00007245456,0.00004980757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016308214,0.00019410759,0.0002532891,0.00009477621,0.000019473307,0.000007605994,0.00021368377,0.00012338701,0.00004005819],"category_scores_gemma":[0.000009682519,0.00019170567,0.00015010466,0.00010577398,0.000043081156,0.000002739093,0.00006768767,0.000078581324,0.000004389472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011503028,0.00012416493,0.0020575367,0.000039570677,0.000075657576,0.000006790919,0.0001848039,0.041687112,0.9548372,0.000008682531,0.000007560381,0.00085586554],"study_design_scores_gemma":[0.0013724859,0.00027688575,0.0035335782,0.000022923723,0.00000858671,0.0000026843072,0.00005813781,0.0036070822,0.989226,0.000009651645,0.0016872779,0.00019474309],"about_ca_topic_score_codex":0.00006001986,"about_ca_topic_score_gemma":0.000004956179,"teacher_disagreement_score":0.03808003,"about_ca_system_score_codex":0.000014353308,"about_ca_system_score_gemma":0.000038518847,"threshold_uncertainty_score":0.78175306},"labels":[],"label_agreement":null},{"id":"W2921561164","doi":"10.5539/jas.v11n4p364","title":"Influence of Cry1Ac Toxin From Bt Cotton on the Soil Microbiota","year":2019,"lang":"en","type":"article","venue":"Journal of Agricultural Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Cry1Ac; Bt cotton; Biology; Context (archaeology); Bacillus thuringiensis; Bacteria; 16S ribosomal RNA; Population; Soil water; Biotechnology; Agronomy; Botany; Genetically modified crops; Horticulture; Transgene; Ecology; Gene","score_opus":0.0033137369833921076,"score_gpt":0.23210262128433412,"score_spread":0.22878888430094202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921561164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990699,0.00020478453,0.000022153288,0.00032829243,0.00013975396,0.000050507584,0.00000391488,0.0000013688625,0.00017932341],"genre_scores_gemma":[0.99946415,0.00005602013,0.00015031877,0.00010663793,0.000094213974,2.7558946e-7,9.408304e-7,0.0000018916724,0.00012555018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935865,0.00001291375,0.00018238771,0.000110648,0.00021014655,0.00012527517],"domain_scores_gemma":[0.9994238,0.000021328215,0.00018980827,0.00013464935,0.00018110713,0.000049334027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002228319,0.00007149942,0.00009207429,0.00001993532,0.000040395855,0.000022362085,0.00041480432,0.00003541469,0.000009712748],"category_scores_gemma":[0.00010050631,0.000033606553,0.00006401814,0.00014551877,0.00008058828,0.000009025738,0.00006238032,0.00008963348,0.0000065518084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009443518,0.00001163645,0.0010530871,0.0000020499333,0.000007062496,2.9606127e-7,0.000066339075,0.013759353,0.98444754,0.00002239758,0.0005447345,0.000076086435],"study_design_scores_gemma":[0.000090039495,0.00014809538,0.3181166,0.000027826445,0.0000038011206,0.000014394062,0.00011136742,0.000007778997,0.68090343,0.000004638928,0.0005277693,0.000044284192],"about_ca_topic_score_codex":0.00001917588,"about_ca_topic_score_gemma":0.000005838185,"teacher_disagreement_score":0.3170635,"about_ca_system_score_codex":0.000013097064,"about_ca_system_score_gemma":0.0000442261,"threshold_uncertainty_score":0.13704354},"labels":[],"label_agreement":null},{"id":"W2921966714","doi":"10.1371/journal.pbio.2006146","title":"The histone methyltransferase G9a regulates tolerance to oxidative stress–induced energy consumption","year":2019,"lang":"en","type":"article","venue":"PLoS Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Canada Research Chairs","keywords":"Biology; Glycogen; Epigenetics; Cell biology; Oxidative stress; Genetics; Biochemistry; Gene","score_opus":0.011350802952624752,"score_gpt":0.30950226756566046,"score_spread":0.2981514646130357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921966714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929938,0.0017613013,0.004115657,0.00028979077,0.00032209925,0.00017562743,0.000026803129,0.000018620256,0.00029635208],"genre_scores_gemma":[0.99826413,0.00041941268,0.00029613415,0.00024867625,0.00014978411,0.000045836176,0.00009515356,0.000014970315,0.0004658779],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990908,0.0000717204,0.00016799167,0.0003471834,0.00005530048,0.00026702468],"domain_scores_gemma":[0.99941117,0.000049908052,0.000031504685,0.00037667583,0.000059498747,0.00007122862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088695415,0.00014911189,0.00015283586,0.000031623425,0.00007273889,0.000011690396,0.00020084494,0.00014440573,0.00004631583],"category_scores_gemma":[0.000047091686,0.00011449938,0.00005693554,0.000058461992,0.000051064664,0.0000018558958,0.000059588387,0.00007046253,0.00004192787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076615856,0.000025540665,0.0013882396,0.0000089614505,0.00006471803,4.4505381e-7,0.00004589252,0.00022087306,0.99372834,0.00044856212,0.00015480876,0.0038370017],"study_design_scores_gemma":[0.00026664103,0.0003144902,0.0016966626,0.000011050373,0.000013271938,0.0000029334124,0.000027463993,0.00015893826,0.9772419,0.000055279554,0.020045241,0.00016614745],"about_ca_topic_score_codex":0.000035083714,"about_ca_topic_score_gemma":0.00010663315,"teacher_disagreement_score":0.019890431,"about_ca_system_score_codex":0.0000141955215,"about_ca_system_score_gemma":0.000021303853,"threshold_uncertainty_score":0.46691492},"labels":[],"label_agreement":null},{"id":"W2922072440","doi":"10.1042/etls20180059","title":"Development of therapeutic genome engineering in laminin-α2-deficient congenital muscular dystrophy","year":2019,"lang":"en","type":"article","venue":"Emerging Topics in Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Hospital for Sick Children; Muscular Dystrophy Association","keywords":"Muscular dystrophy; Congenital muscular dystrophy; Laminin; Genetic enhancement; Cas9; Genome editing; Gene; Bioinformatics; Medicine; Genome; Biology; CRISPR; Genetics; Computational biology; Extracellular matrix","score_opus":0.011379007949083832,"score_gpt":0.278268971272976,"score_spread":0.2668899633238922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922072440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963236,0.0012580445,0.0016386571,0.000037542053,0.00023280538,0.00010102368,7.328756e-7,0.000005211121,0.0004024067],"genre_scores_gemma":[0.99410015,0.000037831913,0.0057017687,0.000027590637,0.00004921549,0.000006867592,0.0000030007102,0.000006521193,0.000067038665],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991297,0.000011208504,0.0002452615,0.00023689153,0.0001589636,0.00021794684],"domain_scores_gemma":[0.99977183,0.0000073491706,0.000033035743,0.00014007787,0.000016090271,0.0000315916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032248755,0.00009572188,0.00011920526,0.00012512026,0.000022738195,0.0000084777375,0.00021201445,0.0000501052,0.000013979111],"category_scores_gemma":[0.00003028253,0.00009324362,0.00003172024,0.00022058428,0.000038890685,0.00000431943,0.00008263191,0.00006498007,0.0000027178576],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009967547,0.00006710063,0.057625797,0.0000872999,0.000031179276,0.0000027475685,0.0020213074,0.1303383,0.8059847,0.0007079279,0.000004385744,0.0031193288],"study_design_scores_gemma":[0.002425875,0.00062939344,0.5520529,0.00017955064,0.000017070079,0.000010558808,0.0031614974,0.02610794,0.3505877,0.00007207198,0.063467935,0.0012875011],"about_ca_topic_score_codex":0.000007789146,"about_ca_topic_score_gemma":0.000020356954,"teacher_disagreement_score":0.4944271,"about_ca_system_score_codex":0.000014354177,"about_ca_system_score_gemma":0.00008169437,"threshold_uncertainty_score":0.38023645},"labels":[],"label_agreement":null},{"id":"W2922098147","doi":"10.1016/j.healun.2019.01.634","title":"CRISPR-Mediated IL-10 Gene Activation as a Novel Gene Therapeutic Strategy in Lung Transplantation","year":2019,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"CRISPR; Biology; Transfection; Viral vector; Cas9; Gene delivery; Genetic enhancement; Genome editing; Gene; Gene expression; Plasmid; Molecular biology; Genetics; Recombinant DNA","score_opus":0.007648810652266979,"score_gpt":0.28347175309747424,"score_spread":0.2758229424452073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922098147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96820986,0.00095480797,0.030303635,0.00018293974,0.0000804039,0.00018536656,0.000014577731,0.0000038744834,0.00006455507],"genre_scores_gemma":[0.99627733,0.003138696,0.00021487598,0.00010944772,0.00008571816,0.0000024931662,0.00010041706,0.000014017278,0.000056978603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992832,0.000057525758,0.00027150242,0.000105240404,0.00014541672,0.00013711113],"domain_scores_gemma":[0.9996888,0.00004670174,0.000082042294,0.00008439296,0.00005830718,0.000039778664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003359619,0.000113464535,0.00012832046,0.00008239605,0.000040109735,0.000017843382,0.000070639995,0.000089137924,0.00002216025],"category_scores_gemma":[0.0000047531325,0.0000880206,0.000044430388,0.000086086984,0.000017346649,0.000020246463,0.0000029766572,0.00012779361,0.0000024300155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071970944,0.000027761618,0.0019696204,0.00009989548,0.000043528067,0.000002220858,0.00059148506,0.008555555,0.9877554,0.000009025532,0.000024426894,0.000201337],"study_design_scores_gemma":[0.0023862487,0.00043638874,0.113289334,0.00008831632,0.00015096327,0.00054275704,0.00019748922,0.00441604,0.878077,0.000027076701,0.00021591474,0.00017253072],"about_ca_topic_score_codex":0.0000336027,"about_ca_topic_score_gemma":0.000026827462,"teacher_disagreement_score":0.11131971,"about_ca_system_score_codex":0.000011986914,"about_ca_system_score_gemma":0.000050156148,"threshold_uncertainty_score":0.35893756},"labels":[],"label_agreement":null},{"id":"W2922527005","doi":"10.1042/bst028a445c","title":"CHARACTERISATION OF THE REGULATORY ELEMENTS INVOLVED IN PARP GENE TRANSCRIPTION","year":2000,"lang":"en","type":"article","venue":"Biochemical Society Transactions","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Icon; Citation; Download; Transcription (linguistics); Library science; Information retrieval; Computer science; World Wide Web; Linguistics","score_opus":0.0070657896875887865,"score_gpt":0.2422316590582775,"score_spread":0.23516586937068873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922527005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99095416,0.0002809882,0.008362468,0.0001340391,0.000065211134,0.00013351771,0.000023918252,0.000007815778,0.000037852027],"genre_scores_gemma":[0.99851274,0.00037365974,0.0007067662,0.000082327344,0.000050547056,0.000022577882,0.000055214165,0.000010101252,0.00018603899],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939024,0.000016342146,0.0002052928,0.00016235438,0.00009771655,0.00012803044],"domain_scores_gemma":[0.999737,0.0000027838203,0.000024909681,0.00018611793,0.000017898547,0.000031235948],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007393233,0.000085442196,0.00007660966,0.0000075912894,0.000041056202,0.000004084261,0.00009472836,0.00013421259,0.000104080085],"category_scores_gemma":[0.0000022352071,0.00007668893,0.0001872612,0.00010987649,0.000055862536,0.0000032595403,0.0000029892756,0.000083648345,0.0000012080649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015627844,0.00006444,0.0005501025,0.0000146787925,0.000022440468,2.3081894e-8,0.00013968551,0.00031162868,0.996031,7.352355e-7,0.00014939264,0.002700241],"study_design_scores_gemma":[0.0003771429,0.000019711202,0.032199737,0.000011499735,0.000016913416,9.859674e-7,0.0000617213,0.00029753297,0.9642888,0.000008682972,0.0026312277,0.00008610291],"about_ca_topic_score_codex":0.000014712896,"about_ca_topic_score_gemma":0.000011430166,"teacher_disagreement_score":0.031742264,"about_ca_system_score_codex":0.000020047131,"about_ca_system_score_gemma":0.000021629095,"threshold_uncertainty_score":0.31272838},"labels":[],"label_agreement":null},{"id":"W2922584262","doi":"10.1038/s41593-019-0365-8","title":"SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons","year":2019,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Prince Edward Island; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Mental Health","keywords":"Neuroscience; Biology; Dendrite (mathematics); Autism spectrum disorder; Synapse; Induced pluripotent stem cell; Transcriptome; Postsynaptic potential; Cellular neuroscience; Excitatory postsynaptic potential; Gene; Genetics; Autism; Gene expression; Inhibitory postsynaptic potential; Psychology","score_opus":0.005644524333388736,"score_gpt":0.2796648824261012,"score_spread":0.27402035809271247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922584262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979581,0.0000949726,0.00081805134,0.0002231207,0.00024346924,0.00014627661,0.00002069906,0.000017249835,0.00047803385],"genre_scores_gemma":[0.9991862,0.000009055473,0.00003363534,0.00016332345,0.000016751235,0.000003968236,0.00001638217,0.000014268184,0.0005563923],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992054,0.00002551688,0.00009039994,0.0003333178,0.00015462565,0.0001907177],"domain_scores_gemma":[0.99959147,0.00001804304,0.000049258408,0.000273009,0.00002245781,0.000045756846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006729268,0.00010770718,0.000101061574,0.00004430924,0.000060854487,0.000014369841,0.00018223963,0.00011856453,0.000007520442],"category_scores_gemma":[0.00012796851,0.00009522176,0.00003762342,0.0002393406,0.00008715462,0.000006369838,0.000059325277,0.00020790705,0.0000012863147],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000046366745,0.00005556971,0.022329045,0.0000056956237,0.0000042641846,0.0000026150326,0.000020514915,0.001960513,0.9752226,0.00031914999,0.000026104566,0.00004929045],"study_design_scores_gemma":[0.0005388794,0.0007934601,0.63764644,0.000018583942,0.000022451823,0.000024190507,0.000020937934,0.00076764286,0.3582006,0.00007805449,0.0016416486,0.0002470741],"about_ca_topic_score_codex":0.0000075778044,"about_ca_topic_score_gemma":0.00012020683,"teacher_disagreement_score":0.617022,"about_ca_system_score_codex":0.0000061673336,"about_ca_system_score_gemma":0.00003680041,"threshold_uncertainty_score":0.38830307},"labels":[],"label_agreement":null},{"id":"W2924182346","doi":"10.1016/j.euroneuro.2017.08.007","title":"GENOME-EDITING OF THE RERE SUPER-ENHANCER ALTERS EXPRESSION OF GENES IN INDEPENDENT SCHIZOPHRENIA GWAS REGIONS","year":2019,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Krembil Foundation","funders":"","keywords":"Enhancer; Genome-wide association study; Biology; Gene; Genetics; Regulation of gene expression; CRISPR; Gene expression; Single-nucleotide polymorphism","score_opus":0.008133964226049187,"score_gpt":0.27972762616030294,"score_spread":0.27159366193425377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924182346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99591273,0.0008466785,0.00016328845,0.00008127038,0.0009837692,0.00026239193,0.000009104271,0.000012221225,0.0017285293],"genre_scores_gemma":[0.99884313,0.0003728201,0.00012566498,0.00013629638,0.00022545671,0.00000574092,0.0000071213517,0.000054526517,0.00022923926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986603,0.0002915442,0.000363924,0.00035084106,0.000108640765,0.00022471689],"domain_scores_gemma":[0.9993073,0.00001808525,0.00014813218,0.00042896756,0.000048539794,0.000049014674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019387506,0.0001543674,0.00017699611,0.00007577981,0.00002414794,0.0000042269776,0.00042209102,0.000056229095,0.000052442418],"category_scores_gemma":[0.000027507074,0.00012957671,0.00010511342,0.00015165597,0.000077914556,0.000004100766,0.00026375797,0.00019408924,0.000009394901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014723855,0.000050550192,0.0050135097,0.00003949451,0.000013982197,0.0000051784664,0.00010074043,0.0046079103,0.9893398,0.0000051493766,0.00022800105,0.00044839512],"study_design_scores_gemma":[0.0017965374,0.00019368199,0.1697889,0.000045120818,0.000016479533,0.00001985235,0.00006988333,0.000050256025,0.819613,0.000004355551,0.008242676,0.00015929736],"about_ca_topic_score_codex":0.0000037265681,"about_ca_topic_score_gemma":0.000005130618,"teacher_disagreement_score":0.16972688,"about_ca_system_score_codex":0.000007096564,"about_ca_system_score_gemma":0.000025573847,"threshold_uncertainty_score":0.52839845},"labels":[],"label_agreement":null},{"id":"W2924476341","doi":"10.1038/s41477-019-0386-z","title":"An efficient DNA- and selectable-marker-free genome-editing system using zygotes in rice","year":2019,"lang":"en","type":"letter","venue":"Nature Plants","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Innovation Cluster (Canada)","funders":"","keywords":"CRISPR; Biology; Cas9; Guide RNA; Genome editing; Selectable marker; Exogenous DNA; Genome; Genetics; Nuclease; DNA; Cell biology; Computational biology; Plasmid; Gene","score_opus":0.004138505671910374,"score_gpt":0.25025333524235815,"score_spread":0.24611482957044778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924476341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98070365,0.014014833,0.0010046904,0.0013083656,0.0013073595,0.00049577357,0.00048863265,0.00004333556,0.0006333746],"genre_scores_gemma":[0.97726905,0.00012629143,0.0013845202,0.014474472,0.004925414,0.000011559055,0.0015563844,0.00011089766,0.00014142938],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983656,0.00006848771,0.00023924121,0.00062981446,0.00022447374,0.00047238544],"domain_scores_gemma":[0.99923056,0.000040117986,0.00010429445,0.00052832183,0.000046374542,0.00005033985],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00021223298,0.00034002648,0.00032904508,0.0001504857,0.000054267246,0.000055102624,0.0003452511,0.0016972212,0.0000024717356],"category_scores_gemma":[0.00005374769,0.00033906964,0.00005066089,0.00009396458,0.000018978973,0.000002746247,0.00013920321,0.0012907373,0.0000023357659],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085475614,0.00004270319,0.0017988171,0.0023951684,0.00020360449,0.00042496572,0.00015179596,0.01229862,0.9105084,0.0000024115654,0.07176396,0.00032407173],"study_design_scores_gemma":[0.004907673,0.0006417978,0.011099627,0.002688306,0.00033405542,0.002582083,0.0005805774,0.08885794,0.22270489,0.00000796524,0.6610655,0.0045295623],"about_ca_topic_score_codex":0.000027285128,"about_ca_topic_score_gemma":0.000016036034,"teacher_disagreement_score":0.6878035,"about_ca_system_score_codex":0.00005232756,"about_ca_system_score_gemma":0.000055992077,"threshold_uncertainty_score":0.9999061},"labels":[],"label_agreement":null},{"id":"W2924595615","doi":"10.1038/s41436-019-0492-3","title":"What do we do now?: Responding to claims of germline gene editing in humans","year":2019,"lang":"en","type":"editorial","venue":"Genetics in Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Germline; Genome editing; Pregnancy; Resistance (ecology); Genetics; Medicine; Biology; Gene; CRISPR","score_opus":0.008977842985914678,"score_gpt":0.3416695091257013,"score_spread":0.3326916661397866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924595615","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17427668,0.090738505,0.002242472,0.0006252047,0.73065305,0.0009705917,0.00010916403,0.000017362807,0.00036696476],"genre_scores_gemma":[0.064373635,0.120773405,0.003348941,0.00012212752,0.8074062,0.00008214067,0.0009526213,0.00024849543,0.0026924578],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964697,0.0000980473,0.0010987468,0.0009411804,0.0007729936,0.00061937724],"domain_scores_gemma":[0.9981296,0.00019677656,0.00024986212,0.00103294,0.000232538,0.00015827436],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012754535,0.00050944724,0.00089573587,0.0010915443,0.000028017292,0.00003439792,0.0006887348,0.0010688734,0.000052488365],"category_scores_gemma":[0.0007306524,0.00051529653,0.00011039633,0.0006595264,0.00010767515,0.0000049768573,0.0003986702,0.00074230763,0.000011167881],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024560554,0.0000850305,0.0010129444,0.0007386523,0.00008560445,0.00004982326,0.0014174697,0.013810259,0.46859124,0.000013397988,0.5052597,0.008690278],"study_design_scores_gemma":[0.0021070212,0.000914984,0.00025094743,0.0035410349,0.000059290884,0.0000036387476,0.000810485,0.000105699975,0.04480328,0.000088734756,0.946715,0.0005998633],"about_ca_topic_score_codex":0.000016524757,"about_ca_topic_score_gemma":0.0002028144,"teacher_disagreement_score":0.4414553,"about_ca_system_score_codex":0.000093058305,"about_ca_system_score_gemma":0.00019078028,"threshold_uncertainty_score":0.9997299},"labels":[],"label_agreement":null},{"id":"W2925067026","doi":"10.1098/rstb.2018.0097","title":"Variability in the durability of CRISPR-Cas immunity","year":2019,"lang":"en","type":"article","venue":"Philosophical Transactions of the Royal Society B Biological Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Environment Research Council; Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Sight Research UK; Université de Montpellier; Centre National de la Recherche Scientifique; Leverhulme Trust","keywords":"CRISPR; Biology; Lytic cycle; Genome editing; Genetics; Bacteriophage; Computational biology; Gene; Virus","score_opus":0.024871966696279703,"score_gpt":0.30644980045056847,"score_spread":0.28157783375428874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2925067026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98298025,0.00011381356,0.013518332,0.002326536,0.000100510624,0.00024097748,0.000017395692,0.0000045081542,0.0006977044],"genre_scores_gemma":[0.9993373,0.000045620043,0.0004629934,0.00010321125,0.000030281688,0.000009513699,0.0000015447425,0.0000019727263,0.0000075546104],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99884725,0.00029320776,0.00025773537,0.0002467561,0.0001862876,0.000168764],"domain_scores_gemma":[0.99929565,0.00021853157,0.00005678525,0.00036409782,0.000039255738,0.000025652971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017772776,0.000097641736,0.00015761222,0.000006793307,0.00012147348,0.000006551862,0.00067885476,0.00015284501,0.00006405471],"category_scores_gemma":[0.00016764778,0.000047948586,0.00033572136,0.0002767777,0.00089076534,0.0000030088086,0.00005034386,0.00022009229,8.8387094e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019610781,0.0020634164,0.49253118,0.00022077444,0.0001476306,2.1736882e-7,0.0011218565,0.055529736,0.43964505,0.0052919756,0.000052536685,0.0031994996],"study_design_scores_gemma":[0.0006624487,0.001264243,0.7857298,0.000034402074,0.0000411014,0.000005319408,0.0008437826,0.0076191197,0.16558115,0.037528623,0.00032942637,0.00036054323],"about_ca_topic_score_codex":0.00008773005,"about_ca_topic_score_gemma":0.0000057916386,"teacher_disagreement_score":0.29319865,"about_ca_system_score_codex":0.000009763635,"about_ca_system_score_gemma":0.000032232972,"threshold_uncertainty_score":0.3282062},"labels":[],"label_agreement":null},{"id":"W2925107547","doi":"10.1007/s10295-019-02160-y","title":"Advances in engineered <i>trans</i>-acting regulatory RNAs and their application in bacterial genome engineering","year":2019,"lang":"en","type":"review","venue":"Journal of Industrial Microbiology & Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Computational biology; Biology; Synthetic biology; Genome engineering; Genome; RNA; Gene; DNA; Function (biology); Regulation of gene expression; Base pair; Genetics; Genome editing","score_opus":0.01341243072065231,"score_gpt":0.26989228927353265,"score_spread":0.25647985855288036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2925107547","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013290066,0.9821349,0.0030931518,0.000044898887,0.0008584057,0.0005108937,0.000048002203,0.000012520531,0.0000071824697],"genre_scores_gemma":[0.018078217,0.98081297,0.00028667675,0.000008199072,0.000619423,0.000018456862,0.00011535033,0.000055048775,0.000005675446],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99791515,0.00009506313,0.0011207511,0.00043196272,0.00003374188,0.00040331093],"domain_scores_gemma":[0.99896234,0.00006945773,0.0005535355,0.00032563607,0.00003659603,0.000052409545],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005164238,0.00044937982,0.0014759444,0.0007428204,0.000017130802,0.0000120998675,0.00042905792,0.0024846618,0.0000033447334],"category_scores_gemma":[0.00014549292,0.0003890114,0.00022995034,0.00030779684,0.00009923159,0.000011212453,0.00013829059,0.0012670882,0.0000011521593],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005398116,0.000026968291,0.000013006895,0.0005117103,0.00007821564,0.000008252934,0.00001581157,0.0003576878,0.5988989,0.0000088728675,0.000013111343,0.40001348],"study_design_scores_gemma":[0.0010689175,0.0003110536,0.0000043355326,0.0012759201,0.000067569075,0.0006929472,0.000027554363,0.000007626532,0.02055803,0.0000034097661,0.9756237,0.00035891903],"about_ca_topic_score_codex":0.0000036350411,"about_ca_topic_score_gemma":0.000018972747,"teacher_disagreement_score":0.9756106,"about_ca_system_score_codex":0.00009093684,"about_ca_system_score_gemma":0.00019862833,"threshold_uncertainty_score":0.9998562},"labels":[],"label_agreement":null},{"id":"W2926334753","doi":"10.1016/j.celrep.2019.03.019","title":"Global Characterization of X Chromosome Inactivation in Human Pluripotent Stem Cells","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; United States-Israel Binational Science Foundation","keywords":"XIST; X-inactivation; Biology; Induced pluripotent stem cell; Epigenetics; Dosage compensation; Embryonic stem cell; X chromosome; Genetics; Long non-coding RNA; Gene silencing; Cell biology; Gene; RNA","score_opus":0.004464958650481352,"score_gpt":0.23741762712618436,"score_spread":0.232952668475703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2926334753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736816,0.00005415874,0.0011519443,0.00000371327,0.00020889824,0.0001621171,0.0000029694809,0.0000049794735,0.0010430476],"genre_scores_gemma":[0.9992261,0.000018260756,0.000032715816,0.000009158325,0.000039528044,0.0000045219326,0.00008706906,0.000007966504,0.0005746584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940664,0.000009027387,0.00022797007,0.0001853826,0.000076139135,0.00009486406],"domain_scores_gemma":[0.99960995,9.666938e-7,0.000116274314,0.00021977905,0.000029777042,0.000023249664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007002194,0.00007102925,0.00009276413,0.000023544124,0.000008252864,0.0000048382535,0.000036044094,0.00007212751,0.0000141677165],"category_scores_gemma":[0.0000017996475,0.00007647107,0.00003211409,0.000068792535,0.000007538856,0.0000027348135,0.000032026954,0.000023865941,0.0000015375326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004491288,0.000033687415,0.018805979,0.000044822922,0.0000035112143,0.0000074791014,0.000017752796,0.00084492576,0.9798805,0.000003916565,0.000010226571,0.00034267228],"study_design_scores_gemma":[0.00012770468,0.000064940024,0.052069183,0.000014110503,0.000002865617,0.000011044454,0.000012868244,0.0000465638,0.94608,0.000006197801,0.0014883254,0.00007614643],"about_ca_topic_score_codex":0.000012076524,"about_ca_topic_score_gemma":0.0000036154513,"teacher_disagreement_score":0.033800486,"about_ca_system_score_codex":0.00002189311,"about_ca_system_score_gemma":0.00002161386,"threshold_uncertainty_score":0.31183997},"labels":[],"label_agreement":null},{"id":"W2926956074","doi":"10.1021/acssynbio.8b00386","title":"A Yeast System for Discovering Optogenetic Inhibitors of Eukaryotic Translation Initiation","year":2019,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Institute of Mental Health; University of Toronto","keywords":"Optogenetics; EIF4E; Eukaryotic translation; Translation (biology); Protein biosynthesis; Initiation factor; Yeast; Biology; Cell biology; Computational biology; Biochemistry; Messenger RNA; Gene; Neuroscience","score_opus":0.009720388037483032,"score_gpt":0.2847557081517817,"score_spread":0.27503532011429865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2926956074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95257854,0.0007525522,0.045348845,0.000027980856,0.00041798764,0.00039723577,0.00004353303,0.000013842322,0.00041946096],"genre_scores_gemma":[0.9985711,0.0000367006,0.0010681726,0.000011205049,0.00011418775,0.000037721373,0.00010895165,0.000022635915,0.000029339933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992305,0.000032349053,0.00025025877,0.0002565268,0.00004641936,0.00018393375],"domain_scores_gemma":[0.9995837,0.000028368908,0.00007812341,0.00023608639,0.000042264182,0.000031428837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013236648,0.00012161047,0.00017334924,0.000054578308,0.000022355815,0.0000049054456,0.00010611318,0.00015720396,0.000006206214],"category_scores_gemma":[0.000028931254,0.00011735581,0.00008542769,0.000056124747,0.000038156475,0.000002648922,0.000030032848,0.00003590509,0.0000068398517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048421294,0.000015306672,0.0027753275,0.00016778585,0.000031903488,9.197825e-8,0.00006002962,0.001307043,0.9909184,0.00033654942,0.000005834786,0.004333307],"study_design_scores_gemma":[0.000573746,0.00037310383,0.0016795932,0.00006175047,0.000034835037,0.000012880453,0.00014205932,0.0009024875,0.994825,0.000043155138,0.0011869998,0.00016440643],"about_ca_topic_score_codex":0.000008242068,"about_ca_topic_score_gemma":0.000005321921,"teacher_disagreement_score":0.045992523,"about_ca_system_score_codex":0.000011283391,"about_ca_system_score_gemma":0.00002771507,"threshold_uncertainty_score":0.4785631},"labels":[],"label_agreement":null},{"id":"W2928730330","doi":"10.1371/journal.pgen.1008101","title":"DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells","year":2019,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Biology; Chromosomal translocation; Recombination; Genetics; DNA; Immunoglobulin class switching; Gene; B cell; Antibody","score_opus":0.006437749248372933,"score_gpt":0.2721289750488462,"score_spread":0.2656912258004733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2928730330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979962,0.000353408,0.0009139257,0.000088372486,0.00011534168,0.00029255816,0.0000112689,0.000010776069,0.00021812318],"genre_scores_gemma":[0.998796,0.000052079875,0.0008262554,0.0000817754,0.00008621048,0.000006861352,0.00004192101,0.000028596276,0.00008034156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991942,0.000023355138,0.00017734518,0.0002851635,0.000095271826,0.000224631],"domain_scores_gemma":[0.99961257,0.000009193031,0.000028468095,0.0002242875,0.000033005002,0.000092483875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000667702,0.00013937295,0.00012590685,0.00008515971,0.00004478707,0.000032705706,0.00010768019,0.00012377334,0.000015177796],"category_scores_gemma":[0.000014119936,0.0001554194,0.000026176021,0.00010428582,0.00000953279,0.00000359303,0.00004630701,0.00010039342,0.000005815965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000476052,0.000023311393,0.002630563,0.00004806767,0.000013963513,5.7409954e-7,0.00039003073,0.00508531,0.9909302,0.000021421238,0.000027224509,0.0008246022],"study_design_scores_gemma":[0.00037569957,0.00018839903,0.0048690937,0.000037014495,0.000013111954,0.0000042965635,0.000083397455,0.0027416437,0.9909245,0.000047628266,0.00051461277,0.00020059841],"about_ca_topic_score_codex":0.0000033683677,"about_ca_topic_score_gemma":0.00013957726,"teacher_disagreement_score":0.0023436665,"about_ca_system_score_codex":0.000020186964,"about_ca_system_score_gemma":0.00002189643,"threshold_uncertainty_score":0.6337819},"labels":[],"label_agreement":null},{"id":"W2929860547","doi":"10.1242/dmm.037259","title":"<i>fs(1)h</i> controls metabolic and immune function and enhances survival via AKT and FOXO in <i>Drosophila</i>","year":2019,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Imperial College London; Medical Research Council Canada; Wellcome Trust; GlaxoSmithKline","keywords":"Immune system; Drosophila (subgenus); Protein kinase B; Biology; Function (biology); PI3K/AKT/mTOR pathway; Cell biology; Immunology; Genetics; Signal transduction; Gene","score_opus":0.004864034721090976,"score_gpt":0.22796580889256093,"score_spread":0.22310177417146995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2929860547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85082275,0.018806443,0.12974086,0.00006294891,0.00015588812,0.0002776305,0.0000229815,0.000012855611,0.000097609925],"genre_scores_gemma":[0.99796766,0.0012914768,0.0003719874,0.00015716645,0.00005560874,0.000038323542,0.000044435594,0.000023282877,0.00005005118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908596,0.000027514676,0.00016578681,0.00039920266,0.00010648883,0.00021503119],"domain_scores_gemma":[0.9995783,0.000010448744,0.000035137127,0.00020515261,0.000024078734,0.00014690607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001483818,0.00018134828,0.00022003328,0.000040984396,0.00003938051,0.000033867538,0.00005660661,0.000079281876,0.0000045510014],"category_scores_gemma":[0.000008143134,0.00017902422,0.000038832623,0.00004434614,0.000028902301,0.00001407228,0.000097998454,0.00006125881,0.0000014513893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001995742,0.000036149082,0.0003509312,0.00004660842,0.000032496595,0.0000019050615,0.000030713065,0.00072710775,0.99012476,0.006802626,0.0000022649851,0.0016448717],"study_design_scores_gemma":[0.008469653,0.0009066222,0.02427135,0.00011350412,0.0003726478,0.000024115576,0.00022400665,0.08750952,0.69547355,0.17993903,0.0011695935,0.0015264241],"about_ca_topic_score_codex":0.0000242495,"about_ca_topic_score_gemma":0.000015814214,"teacher_disagreement_score":0.29465124,"about_ca_system_score_codex":0.0000028304162,"about_ca_system_score_gemma":0.000016781545,"threshold_uncertainty_score":0.7300396},"labels":[],"label_agreement":null},{"id":"W2931234257","doi":"10.1242/jeb.175737","title":"Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; University of Ottawa","keywords":"Gene knockdown; RNA interference; Gene knockout; Morpholino; Zebrafish; Knockout mouse; Phenotype; Biology; CRISPR; Computational biology; Transcription activator-like effector nuclease; Genetics; Genome editing; Gene; RNA","score_opus":0.026466405328526472,"score_gpt":0.34048114794948964,"score_spread":0.3140147426209632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2931234257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98944014,0.009611168,0.00020885962,0.00006934302,0.0002958279,0.00023233125,0.000013494581,6.227787e-7,0.00012818743],"genre_scores_gemma":[0.99898535,0.00007631074,0.00050228706,0.00007939677,0.00030368142,0.000016658645,0.000023146222,0.0000066436364,0.0000065333174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992511,0.000066967776,0.00035596077,0.00013790226,0.000052899468,0.00013513863],"domain_scores_gemma":[0.99956834,0.000022000308,0.00022591278,0.00012905645,0.0000374602,0.00001719983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017804095,0.000111990346,0.0002808007,0.000052696665,0.000011601532,0.0000024502083,0.00018200646,0.00012682597,0.00002594971],"category_scores_gemma":[0.0000058529818,0.00007735574,0.00011396383,0.00006165863,0.00006568798,0.0000049487535,0.00003823697,0.0001234653,5.599555e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042518522,0.00018961658,0.0055553582,0.00001593262,0.000057860805,3.4651373e-7,0.0023199485,0.00021354876,0.9909978,0.0000715651,0.0000690159,0.000083852145],"study_design_scores_gemma":[0.001458486,0.001977883,0.011743752,0.0000212072,0.000007088345,0.000014505152,0.010492664,0.00006900763,0.97196794,0.0000513033,0.0021096654,0.00008647453],"about_ca_topic_score_codex":0.0000053026934,"about_ca_topic_score_gemma":0.000002700519,"teacher_disagreement_score":0.019029805,"about_ca_system_score_codex":0.000014255703,"about_ca_system_score_gemma":0.000023713912,"threshold_uncertainty_score":0.31544757},"labels":[],"label_agreement":null},{"id":"W2931368040","doi":"10.1038/s41586-019-1076-8","title":"Precise therapeutic gene correction by a simple nuclease-induced double-stranded break","year":2019,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; University of Massachusetts","keywords":"Biology; Frameshift mutation; Genome editing; Genetics; CRISPR; Cas9; Homology directed repair; Mutation; DNA repair; Gene; Nucleotide excision repair","score_opus":0.00488285864890066,"score_gpt":0.27910217761371053,"score_spread":0.2742193189648099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2931368040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943541,0.0021375655,0.0008395342,0.00008612836,0.00084574695,0.00026307942,0.000018108973,0.000032459935,0.0014232413],"genre_scores_gemma":[0.9975005,0.00007205261,0.00006583264,0.00028842446,0.00017936328,0.00000945193,0.00019665084,0.000029180681,0.0016585395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929875,0.000013011646,0.00010087096,0.00028411802,0.000112001435,0.00019123637],"domain_scores_gemma":[0.9995708,0.00000605994,0.000029382147,0.00028882956,0.00004440138,0.00006053287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005769158,0.00013978424,0.00010695591,0.000023134604,0.000034745706,0.000021378579,0.00012375177,0.00078334904,0.00008131217],"category_scores_gemma":[0.0000070226124,0.00013148236,0.00007575222,0.00007558991,0.000007859433,0.0000028373897,0.000028528422,0.0004651216,0.000027431326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015810823,0.00002940756,0.00035300423,0.000010113564,0.000038145135,6.7243866e-7,0.000023232038,0.00016838791,0.9841478,0.000004062651,0.010084458,0.004982643],"study_design_scores_gemma":[0.0011626375,0.00015079747,0.0011097548,0.00000567919,0.000018201843,0.000021388263,0.000025353456,0.00040795121,0.9201692,0.000013104981,0.07673135,0.00018460167],"about_ca_topic_score_codex":0.000012754703,"about_ca_topic_score_gemma":0.000014966191,"teacher_disagreement_score":0.06664689,"about_ca_system_score_codex":0.000012132737,"about_ca_system_score_gemma":0.000023167968,"threshold_uncertainty_score":0.6041905},"labels":[],"label_agreement":null},{"id":"W2932613074","doi":"10.1016/s1383-5718(03)00013-5","title":"On the origin of unusual mutations recovered from the transgenic assay","year":2003,"lang":"en","type":"article","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Mutant; Biology; Genetics; Gene; Mutation; Genome; Point mutation; Transgene; Bacteriophage; Molecular biology; Escherichia coli","score_opus":0.024169077024386473,"score_gpt":0.31576389191744186,"score_spread":0.2915948148930554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2932613074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99340063,0.0010887126,0.004195848,0.0004018884,0.000094326315,0.00035406306,0.00015006438,0.0000046326727,0.000309827],"genre_scores_gemma":[0.9984816,0.00043001573,0.00034666783,0.00018446738,0.00004375302,0.000094017,0.00011773854,0.000020688873,0.0002810903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982966,0.0006634126,0.00022195006,0.00032145943,0.00023659781,0.00025993653],"domain_scores_gemma":[0.99894124,0.00060622033,0.000046828947,0.0003244173,0.000014163074,0.00006714491],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061217445,0.00014046584,0.00011399825,0.000047717633,0.00029018518,0.00001780689,0.00018304856,0.00013989917,0.00034475533],"category_scores_gemma":[0.00023093019,0.00009886374,0.00006600263,0.00011984173,0.00045616753,0.0000030529573,0.000043371427,0.00015709968,0.000018009174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009674445,0.00014875224,0.00460723,0.00000797324,0.00015450931,0.0000054873144,0.0005632025,0.006829901,0.9788824,0.0007116652,0.0005577275,0.007434409],"study_design_scores_gemma":[0.0009794127,0.0008515243,0.110346854,0.000012835928,0.00007094499,0.000026658277,0.0028489004,0.0005705604,0.8721885,0.00235517,0.009480066,0.00026856535],"about_ca_topic_score_codex":0.000029738403,"about_ca_topic_score_gemma":0.0000596752,"teacher_disagreement_score":0.106693886,"about_ca_system_score_codex":0.00002402482,"about_ca_system_score_gemma":0.000043319236,"threshold_uncertainty_score":0.40315464},"labels":[],"label_agreement":null},{"id":"W2933677450","doi":"10.1007/978-3-030-03095-7_16","title":"Genome Editing for Muscle Gene Therapy","year":2019,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children; SickKids Foundation","funders":"","keywords":"CRISPR; Genome editing; Zinc finger nuclease; Duchenne muscular dystrophy; Biology; Transcription activator-like effector nuclease; Genetic enhancement; Gene; Cas9; Computational biology; Dystrophin; Muscle disorder; Genetics; Bioinformatics; Medicine","score_opus":0.012167402102693953,"score_gpt":0.26620702615475794,"score_spread":0.254039624052064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2933677450","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0051533645,0.016701575,0.11243302,0.00013906987,0.0016863578,0.0016417439,0.00029671183,0.000077561985,0.8618706],"genre_scores_gemma":[0.018607063,0.0022168304,0.0040262504,0.00034723303,0.0035098046,0.000028639382,0.0010549814,0.0001686979,0.9700405],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991988,0.0000018552278,0.00016598038,0.00035944895,0.00007611151,0.00019782316],"domain_scores_gemma":[0.9994664,0.000007802632,0.000054979675,0.00035869144,0.000063026826,0.000049096885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007036792,0.00023197597,0.00018152004,0.00003364957,0.00003207208,0.00001563313,0.00014898369,0.0003134503,0.00018906141],"category_scores_gemma":[0.0000064793026,0.00022278386,0.00019271241,0.000004954979,0.00001686442,6.435852e-7,0.00005826371,0.00007518647,0.000035423443],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020548525,0.0000074686386,0.0000033966915,0.000048660688,0.00014494776,0.0000010204961,0.00001287603,0.00027134555,0.98416096,0.0015818216,0.0026418658,0.011105066],"study_design_scores_gemma":[0.00035013744,0.0001790271,0.00005140096,0.000008914346,0.000013584259,0.0000039565725,0.000003959597,0.000027939537,0.07391493,0.00018177161,0.92497295,0.00029141587],"about_ca_topic_score_codex":0.000001355759,"about_ca_topic_score_gemma":0.0000043247924,"teacher_disagreement_score":0.9223311,"about_ca_system_score_codex":0.000008330053,"about_ca_system_score_gemma":0.000043512708,"threshold_uncertainty_score":0.9084862},"labels":[],"label_agreement":null},{"id":"W2935366323","doi":"10.1101/597849","title":"Suppression of unwanted CRISPR/Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Canadian Institute for Advanced Research; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Genome editing; Guide RNA; Cas9; Computational biology; Cleavage (geology); Computer science; Genome engineering; RNA; Biology; Genetics; Gene","score_opus":0.007565348199331913,"score_gpt":0.27325136991031324,"score_spread":0.2656860217109813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2935366323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9676247,0.0007409802,0.029866425,0.000047752106,0.0006030417,0.00051012926,0.00050048844,0.000052969855,0.000053465363],"genre_scores_gemma":[0.9965524,0.00012820735,0.0028303543,0.000028322242,0.0002916597,0.000031613297,0.000023799059,0.000099191355,0.00001443456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975345,0.000079171194,0.0008893039,0.0007381562,0.00037556258,0.0003833081],"domain_scores_gemma":[0.9975117,0.000044292472,0.000697595,0.0010245758,0.0005819402,0.00013990993],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048264553,0.0004423558,0.0005670292,0.00013083918,0.00007834522,0.000036726127,0.00047221256,0.00065597857,0.00001445496],"category_scores_gemma":[0.000584113,0.00048875343,0.00014723274,0.0001931849,0.00010612169,0.00001045844,0.0006110185,0.000389996,0.0000029190974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007744775,0.00010218661,0.0029008044,0.0006701462,0.00013100366,0.0000038115395,0.000008908096,0.000399397,0.99417245,0.000013584901,0.0015159809,0.000004289645],"study_design_scores_gemma":[0.00047690232,0.00020984586,0.006732507,0.0004559314,0.000077288154,6.17051e-8,0.000011339082,0.00078206015,0.98887867,3.837545e-7,0.0019469091,0.00042811708],"about_ca_topic_score_codex":0.000050185856,"about_ca_topic_score_gemma":0.0000017973222,"teacher_disagreement_score":0.02892767,"about_ca_system_score_codex":0.00006002865,"about_ca_system_score_gemma":0.00044438007,"threshold_uncertainty_score":0.9997564},"labels":[],"label_agreement":null},{"id":"W2935834115","doi":"10.1016/j.mrgentox.2019.04.002","title":"In vitro mammalian cell mutation assays based on transgenic reporters: A report of the International Workshop on Genotoxicity Testing (IWGT)","year":2019,"lang":"en","type":"review","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Rijksinstituut voor Volksgezondheid en Milieu; Health Canada; Chugai Pharmaceutical","keywords":"In vitro toxicology; Transgene; Biology; Genotoxicity; Computational biology; In vitro; Genetics; Gene; Toxicity; Chemistry","score_opus":0.04996586999521497,"score_gpt":0.3575814444961564,"score_spread":0.30761557450094146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2935834115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6138316,0.37537107,0.0026877078,0.00034114427,0.0013097342,0.0046451343,0.0004273476,0.000025286461,0.0013609657],"genre_scores_gemma":[0.8555889,0.14098835,0.0010843463,0.00015802948,0.00016938902,0.00037358812,0.0005846367,0.00009946973,0.00095325295],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693996,0.00048675775,0.0007909636,0.00084996683,0.00054047845,0.0003918773],"domain_scores_gemma":[0.9985517,0.00033820493,0.00034955668,0.000641143,0.000026400148,0.00009299558],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00084894744,0.00036375228,0.00053181197,0.00033944682,0.00011733789,0.000027314629,0.00039130356,0.00051440345,0.0000652268],"category_scores_gemma":[0.00028548716,0.00031484262,0.0002443025,0.00027232326,0.00023254358,0.0000058981645,0.0001546555,0.00044387323,0.00001223895],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004632704,0.001113619,0.0009893342,0.0036068975,0.0002892904,0.00090441044,0.00024176986,0.04587377,0.37790397,0.0000029578719,0.00022570536,0.568385],"study_design_scores_gemma":[0.0054262625,0.0036725139,0.039299656,0.0041237734,0.0011548355,0.0021702729,0.001031675,0.011903586,0.7496496,0.00008398863,0.17850322,0.002980645],"about_ca_topic_score_codex":0.000018055905,"about_ca_topic_score_gemma":0.000015396703,"teacher_disagreement_score":0.56540436,"about_ca_system_score_codex":0.00019036866,"about_ca_system_score_gemma":0.00019743698,"threshold_uncertainty_score":0.9999304},"labels":[],"label_agreement":null},{"id":"W2936179117","doi":"10.1016/j.exphem.2019.03.004","title":"ETV6-RUNX1 interacts with a region in SPIB intron 1 to regulate gene expression in pre-B-cell acute lymphoblastic leukemia","year":2019,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Intron; Gene; RUNX1; Biology; Lymphoblastic Leukemia; ETV6; Leukemia; Genetics; Gene expression; Cancer research; Molecular biology; Cell biology; Transcription factor; Chromosomal translocation","score_opus":0.003545811376179333,"score_gpt":0.26768879377427773,"score_spread":0.2641429823980984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936179117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99581116,0.0014359796,0.0017457698,0.00003636307,0.00017970502,0.00042447442,0.0000014572837,0.000013613286,0.00035147584],"genre_scores_gemma":[0.99740845,0.000023304381,0.0018380188,0.000118193275,0.000037795522,0.00009022178,0.000036585487,0.000035582067,0.00041182627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987619,0.000039719507,0.0002608275,0.0004909864,0.00008830826,0.00035827575],"domain_scores_gemma":[0.99947155,0.000011068637,0.000053360825,0.00035798823,0.000013591954,0.000092435555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048944417,0.00021865052,0.0002688964,0.00012952415,0.000015739692,0.000010028288,0.0001705671,0.00016633356,0.000023525721],"category_scores_gemma":[0.000006907512,0.00020297946,0.00003864748,0.0001155232,0.000028220415,0.0000076195474,0.00018749603,0.000099084595,0.00003116319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007448417,0.000108757005,0.0037589367,0.000026521368,0.000009950532,0.000069274305,0.0006066437,0.0025184648,0.99184793,0.00004810267,0.00019181412,0.00006874309],"study_design_scores_gemma":[0.0020105238,0.0007045,0.0023809425,0.00011134046,0.0000035961837,0.00027675822,0.0002076535,0.00033703714,0.99334973,0.0000053513822,0.00036791217,0.00024462558],"about_ca_topic_score_codex":0.000039986382,"about_ca_topic_score_gemma":0.000055755892,"teacher_disagreement_score":0.0021814278,"about_ca_system_score_codex":0.00012241439,"about_ca_system_score_gemma":0.000055385663,"threshold_uncertainty_score":0.8277262},"labels":[],"label_agreement":null},{"id":"W2936337436","doi":"10.1038/s41436-019-0482-5","title":"CRISPR in the North American popular press","year":2019,"lang":"en","type":"article","venue":"Genetics in Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Institute of Health Economics; Université de Montréal; University of Alberta","funders":"Genome Canada","keywords":"CRISPR; Context (archaeology); Social media; Promotion (chess); Internet privacy; Political science; Biology; World Wide Web; Computer science; Genetics; Law; Politics","score_opus":0.00988191434564925,"score_gpt":0.31700296562472596,"score_spread":0.30712105127907674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936337436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939035,0.0033553229,0.00090779027,0.0003648507,0.00019681608,0.00025811838,0.0000025800407,0.0000044830317,0.0010065413],"genre_scores_gemma":[0.997152,0.0013313565,0.00042849552,0.0006081062,0.00024714635,0.00001914217,0.00003953449,0.000016796235,0.00015746185],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990192,0.000054908407,0.00022530125,0.00026378367,0.00018154629,0.00025526018],"domain_scores_gemma":[0.99939364,0.000014794274,0.000038661456,0.00049198593,0.000021579268,0.00003936509],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026079954,0.00013093784,0.00017256293,0.00005626751,0.000012976061,0.0000058918326,0.00032148242,0.00004440786,0.000010725219],"category_scores_gemma":[0.00005211245,0.00009593666,0.000026226822,0.00020266637,0.00008135705,8.48718e-7,0.00006329836,0.00014892007,0.0000062159734],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062368956,0.000099564015,0.8896705,0.00007436238,0.00002750154,0.000029151406,0.0013305407,0.016765153,0.075865254,0.00009382877,0.0037609942,0.012220779],"study_design_scores_gemma":[0.0014534544,0.0008630459,0.82714146,0.00004225834,0.000019933392,0.000024349338,0.0008872333,0.0011169274,0.011699171,0.000041167874,0.15637942,0.00033157607],"about_ca_topic_score_codex":0.00014296442,"about_ca_topic_score_gemma":0.0009688311,"teacher_disagreement_score":0.15261842,"about_ca_system_score_codex":0.000008823919,"about_ca_system_score_gemma":0.000013737418,"threshold_uncertainty_score":0.39121833},"labels":[],"label_agreement":null},{"id":"W2936889661","doi":"10.1038/s41477-019-0405-0","title":"Generation of herbicide tolerance traits and a new selectable marker in wheat using base editing","year":2019,"lang":"en","type":"letter","venue":"Nature Plants","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":345,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Selectable marker; Genome editing; Acetolactate synthase; Biology; Glufosinate; Sulfonylurea; Agronomy; Transgene; Biotechnology; Genetics; Gene; CRISPR; Glyphosate","score_opus":0.014452178384303235,"score_gpt":0.27401677960612614,"score_spread":0.2595646012218229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936889661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96886414,0.021021817,0.0019166614,0.0064451094,0.00083782244,0.0004048133,0.00016206583,0.000010108731,0.00033743615],"genre_scores_gemma":[0.89916146,0.0005932292,0.0077365707,0.075651966,0.013122311,0.000009353325,0.001476827,0.00012420269,0.0021240858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991068,0.000027176628,0.00018476976,0.00032761617,0.00012639811,0.00022718695],"domain_scores_gemma":[0.9997452,0.000015347889,0.0000691015,0.00011660678,0.00002841124,0.000025352925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081734666,0.00018828572,0.00022985604,0.000072375406,0.000015887723,0.000014979731,0.000083443854,0.0010404737,0.000008981543],"category_scores_gemma":[0.000037206482,0.00019406708,0.000036866248,0.00005409208,0.000009031051,0.0000034135783,0.000031848125,0.0007065203,4.9169626e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017596334,0.0000041301687,0.0004717377,0.0001532562,0.000021734897,0.000017244287,0.000023061433,0.0012661482,0.76268417,1.5811251e-7,0.23458171,0.0007590434],"study_design_scores_gemma":[0.0014437493,0.00011313508,0.0033243718,0.0007455417,0.000057889563,0.00021403527,0.000013969642,0.014616135,0.72869265,0.0000068845748,0.25003353,0.00073813193],"about_ca_topic_score_codex":0.00005267773,"about_ca_topic_score_gemma":0.00009316503,"teacher_disagreement_score":0.069702715,"about_ca_system_score_codex":0.000013078757,"about_ca_system_score_gemma":0.000083668456,"threshold_uncertainty_score":0.8025086},"labels":[],"label_agreement":null},{"id":"W2937126128","doi":"10.1016/j.celrep.2019.02.041","title":"Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Canadian Institute for Advanced Research; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Biology; CRISPR; Gene; Computational biology; Context (archaeology); Genetics; Genome; Stem cell; Cellular differentiation; Regenerative medicine; Embryonic stem cell; Cell biology","score_opus":0.008317772701550378,"score_gpt":0.26204127803812693,"score_spread":0.25372350533657656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937126128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946158,0.0015784139,0.0026156632,0.0000071416894,0.0005377811,0.0005003653,0.000012259412,0.000017514223,0.00011506827],"genre_scores_gemma":[0.99530804,0.00017752463,0.00048318243,0.00001424121,0.00018705078,0.00004317082,0.0001192673,0.000030596384,0.0036369471],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892724,0.000012051721,0.0002907002,0.00043031553,0.0001079524,0.00023175142],"domain_scores_gemma":[0.9993911,0.0000051888132,0.00013153131,0.0003290091,0.000067357476,0.000075806485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015908259,0.00016639214,0.00016806442,0.000030637577,0.00006585744,0.00005386823,0.00006903096,0.000116640105,0.000017940161],"category_scores_gemma":[0.000002810968,0.00016304714,0.00009066474,0.000024753268,0.000026843702,0.0000043841137,0.00007746564,0.000043438275,0.000003398314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016590862,0.000020974865,0.0030968345,0.00012769224,0.000027172806,0.000026426971,0.000028543445,0.0001225479,0.9961878,0.000002760462,0.00006301044,0.0002796554],"study_design_scores_gemma":[0.00031192866,0.00009098058,0.004480083,0.000008984769,0.000031373896,0.00007717427,0.000055475062,0.000036948684,0.9909995,0.000021195177,0.0036801526,0.00020616956],"about_ca_topic_score_codex":0.000008904331,"about_ca_topic_score_gemma":0.0000065054583,"teacher_disagreement_score":0.0051882565,"about_ca_system_score_codex":0.0000062574477,"about_ca_system_score_gemma":0.000034501532,"threshold_uncertainty_score":0.66488695},"labels":[],"label_agreement":null},{"id":"W2938052030","doi":"10.1101/612887","title":"Scalable, FACS-Free Genome-Wide Phenotypic Screening","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; University of Toronto","funders":"Sickkids Research Institute; Hospital for Sick Children","keywords":"Phenotype; CRISPR; Genome; Genetic screen; Computational biology; Cas9; Phenotypic screening; Biology; Cell sorting; Cell; Function (biology); Sorting; Genetics; Gene; Computer science","score_opus":0.008721810389380361,"score_gpt":0.22848573657222523,"score_spread":0.21976392618284488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2938052030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84571826,0.007856925,0.1433244,0.00013673534,0.0014249865,0.000884508,0.00033415025,0.00022949524,0.00009055506],"genre_scores_gemma":[0.98307246,0.0005727889,0.014628664,0.00030815374,0.0009736466,0.000112173584,0.000005565208,0.000243077,0.000083497376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968232,0.000076774,0.0005398601,0.0013758171,0.00036763566,0.00081670814],"domain_scores_gemma":[0.99623436,0.000028012018,0.0002552378,0.0028499328,0.00032164634,0.00031080018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042720526,0.00074202777,0.00057995296,0.00019646973,0.00013167846,0.00017957305,0.0012265247,0.0008653649,0.000056038763],"category_scores_gemma":[0.00032521994,0.0008596154,0.00028108002,0.00024489462,0.00009053592,0.00000893135,0.0017117268,0.0006845344,0.00009772689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004458321,0.000059089514,0.011951692,0.0003789152,0.00029096956,0.000014938852,0.0000048407646,0.009750287,0.9760509,0.000034545552,0.0014142664,0.000004979647],"study_design_scores_gemma":[0.001148966,0.00012791246,0.16809933,0.0002540521,0.00014687772,4.8000185e-8,0.000004835028,0.0008564483,0.7710277,0.0000025155707,0.056655314,0.0016760438],"about_ca_topic_score_codex":0.000027749924,"about_ca_topic_score_gemma":0.0000038016726,"teacher_disagreement_score":0.20502323,"about_ca_system_score_codex":0.0000754651,"about_ca_system_score_gemma":0.00034005748,"threshold_uncertainty_score":0.9993855},"labels":[],"label_agreement":null},{"id":"W2938233269","doi":"10.1089/nat.2018.0758","title":"Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9","year":2019,"lang":"en","type":"article","venue":"Nucleic Acid Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"University of Massachusetts Medical School; National Institute of General Medical Sciences; U.S. Department of Defense","keywords":"CRISPR; Cas9; RNA; Nucleic acid; DNA; Oligonucleotide; Trans-activating crRNA; Biology; Effector; Genome editing; Computational biology; Guide RNA; Gene; Enzyme; Biochemistry","score_opus":0.009876524100314652,"score_gpt":0.27613690469935004,"score_spread":0.2662603805990354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2938233269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9772376,0.0022185843,0.018065296,0.00019260994,0.0005577393,0.00035086734,0.00002480237,0.00004175537,0.0013107811],"genre_scores_gemma":[0.99579364,0.00035457368,0.0025960868,0.0005470942,0.00023829221,0.00000857381,0.000060421233,0.00007727892,0.00032401993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984974,0.00005416763,0.00040590533,0.00040624104,0.00028079763,0.00035544182],"domain_scores_gemma":[0.9989918,0.000017436225,0.00013629292,0.0006054869,0.0001593999,0.00008959488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019927474,0.0002821928,0.00029130472,0.000081006845,0.00006524779,0.00003076868,0.0003362334,0.00027005654,0.00016073957],"category_scores_gemma":[0.000020684696,0.00028126687,0.00018117955,0.00016465876,0.000085873944,0.0000097465645,0.000111438865,0.00015153801,0.000083260216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006209729,0.000083996136,0.003226156,0.00004582445,0.00014414042,0.0000014868431,0.00016168787,0.00043156598,0.9922955,0.00019433146,0.0004461585,0.0029070652],"study_design_scores_gemma":[0.0008151352,0.0003486712,0.0042730686,0.00002457147,0.000057723686,0.0000135793725,0.00015116313,0.00066162244,0.9716719,0.000075251286,0.021570532,0.00033680862],"about_ca_topic_score_codex":0.0000046146665,"about_ca_topic_score_gemma":0.000004221957,"teacher_disagreement_score":0.021124372,"about_ca_system_score_codex":0.000019900368,"about_ca_system_score_gemma":0.00008774164,"threshold_uncertainty_score":0.99996394},"labels":[],"label_agreement":null},{"id":"W2938307111","doi":"10.1016/j.celrep.2019.03.047","title":"Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":247,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Calgary; University of Toronto","funders":"National Cancer Institute; Genome Canada; Canadian Institutes of Health Research; Cancer Prevention and Research Institute of Texas; University of Texas MD Anderson Cancer Center; Terry Fox Research Institute","keywords":"CRISPR; Biology; Temozolomide; Genome; Gene; Glioblastoma; Computational biology; Genetics; Cas9; Stem cell; Genome editing; Cancer research","score_opus":0.004558563094037195,"score_gpt":0.21902173114899395,"score_spread":0.21446316805495677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2938307111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98639446,0.00084141834,0.011841841,0.000008923771,0.00018688718,0.0003391646,0.000006889815,0.000012370206,0.0003680535],"genre_scores_gemma":[0.9980302,0.00009436277,0.0009212485,0.000034006138,0.000036354737,0.000009506894,0.0000052950736,0.000032613905,0.0008364076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998602,0.00005399182,0.00043332716,0.0004886028,0.00014005293,0.00028204915],"domain_scores_gemma":[0.99912924,0.00003563401,0.00014088853,0.0005400739,0.000060400187,0.000093762435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034509064,0.00020258884,0.00028563512,0.00007984906,0.0000238646,0.000013761007,0.00005549983,0.00015259793,0.000017900002],"category_scores_gemma":[0.000020238422,0.00021236554,0.0000777129,0.00007434032,0.000051367562,0.0000041249045,0.00013923085,0.00009766805,0.0000036009337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032016676,0.00003885258,0.017727476,0.00013600425,0.000013147577,0.00015162471,0.00009053256,0.003891644,0.97763145,0.000004268594,0.000026827072,0.00025614467],"study_design_scores_gemma":[0.00025327742,0.00028453773,0.018316256,0.000020373034,0.0000138040805,0.00015699834,0.0003151774,0.00020257558,0.97961956,0.00009725843,0.00049085886,0.00022934028],"about_ca_topic_score_codex":0.000045179928,"about_ca_topic_score_gemma":0.00009117505,"teacher_disagreement_score":0.011635752,"about_ca_system_score_codex":0.000015649619,"about_ca_system_score_gemma":0.000047357033,"threshold_uncertainty_score":0.86600155},"labels":[],"label_agreement":null},{"id":"W2939295728","doi":"10.1016/j.gde.2019.03.002","title":"Genetic interaction networks in cancer cells","year":2019,"lang":"en","type":"review","venue":"Current Opinion in Genetics & Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; National Institute for Health and Care Research; Canadian Institutes of Health Research; Health Canada; National Institutes of Health; National Health Research Institutes","keywords":"Biology; Phenotype; Genome; Genetics; CRISPR; Gene; Computational biology; Genome editing; Disease; Genetic screen; Model organism; Genetic model; Gene interaction; Genotype-phenotype distinction","score_opus":0.0678829956231653,"score_gpt":0.42315746394642517,"score_spread":0.3552744683232599,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939295728","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003361146,0.983158,0.0040721577,0.0000028022491,0.011406957,0.0009684646,0.000012838244,0.000010123072,0.00003254355],"genre_scores_gemma":[0.00027719693,0.99694467,0.0009955013,0.000007004835,0.0007584624,0.0004565889,0.0004111395,0.00009022632,0.00005922794],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972865,0.00010061301,0.0010461626,0.0008192358,0.00020814581,0.0005393494],"domain_scores_gemma":[0.99911475,0.00002286894,0.00023925959,0.00047144244,0.000047000554,0.000104669954],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018741051,0.0005709235,0.00080853107,0.0003340728,0.000028514723,0.000039531442,0.00040413786,0.00042802756,0.000030203548],"category_scores_gemma":[0.000010006233,0.0005903035,0.00018622322,0.00031870758,0.000023920922,0.0000026263945,0.00031478258,0.00048679614,0.000041933654],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000059255694,0.00009174914,0.00033843395,0.0061181267,0.00004833715,7.161784e-7,0.000059828657,0.019867603,0.000037092184,0.0000012991115,0.0009670611,0.97246385],"study_design_scores_gemma":[0.00030438913,0.000037619455,0.00060310675,0.0081970105,0.000036636433,0.0000061751825,0.0000092869805,0.0005740999,0.00019159677,0.0000012080691,0.98937166,0.000667206],"about_ca_topic_score_codex":0.0000077093455,"about_ca_topic_score_gemma":0.000042506646,"teacher_disagreement_score":0.98840463,"about_ca_system_score_codex":0.00025000062,"about_ca_system_score_gemma":0.0005680668,"threshold_uncertainty_score":0.9996548},"labels":[],"label_agreement":null},{"id":"W2939400822","doi":"10.1371/journal.pbio.3000236","title":"Epigenetic regulator G9a provides glucose as a sweet key to stress resistance","year":2019,"lang":"en","type":"letter","venue":"PLoS Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Adaptive response; Epigenetics; Cell biology; Oxidative stress; Regulator; Adaptation (eye); Genetics; Gene; Neuroscience; Biochemistry","score_opus":0.008893219963668203,"score_gpt":0.28273827439343285,"score_spread":0.27384505442976464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939400822","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59102166,0.036575153,0.0050002076,0.34640086,0.0040767626,0.0052506933,0.0022243012,0.0003135649,0.009136797],"genre_scores_gemma":[0.27144632,0.0019285788,0.0070618163,0.59519315,0.018696796,0.0009769854,0.00859106,0.00069790817,0.09540741],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972511,0.00013575003,0.0004340183,0.0012097082,0.0001799028,0.00078953773],"domain_scores_gemma":[0.9982303,0.00006141233,0.00014677556,0.0013026178,0.0001399703,0.00011894029],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000109138055,0.0005606011,0.0005854293,0.00015096887,0.00006301336,0.000038479135,0.0007219308,0.0014534874,0.00008025054],"category_scores_gemma":[0.00026986556,0.00054153166,0.00020467027,0.00012713595,0.00010291937,0.0000019301451,0.00034022753,0.0005722095,0.0003005159],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089641646,0.000040939532,0.00041943695,0.00039640686,0.00026178255,0.000039561073,0.000056263496,0.000080868034,0.44593996,0.000020542911,0.55228966,0.00036494507],"study_design_scores_gemma":[0.00023196885,0.00039033292,0.00013981137,0.000104124534,0.00005845225,0.000009856348,0.000008553327,0.000008067298,0.26184088,0.00008256603,0.7365869,0.0005384592],"about_ca_topic_score_codex":0.000030438465,"about_ca_topic_score_gemma":0.000102699574,"teacher_disagreement_score":0.31957534,"about_ca_system_score_codex":0.00004112913,"about_ca_system_score_gemma":0.00017390763,"threshold_uncertainty_score":0.9998428},"labels":[],"label_agreement":null},{"id":"W2940134047","doi":"10.1101/609040","title":"Functional Profiling of Single CRISPR/Cas9-Edited Human Long-Term Hematopoietic Stem Cells","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"University of Toronto; Terry Fox Foundation; Government of Ontario","keywords":"CRISPR; Haematopoiesis; Biology; Stem cell; Hematopoietic stem cell; Cell biology; Genome editing; Computational biology; Cas9; Xenotransplantation; Single-cell analysis; Embryonic stem cell; Cell; Transplantation; Genetics; Gene; Medicine","score_opus":0.015492606023885497,"score_gpt":0.2482882943757915,"score_spread":0.232795688351906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940134047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9657987,0.0021484294,0.029285053,0.00001639527,0.0017937896,0.0006859541,0.00016370403,0.000096272735,0.000011732786],"genre_scores_gemma":[0.9975974,0.000090085145,0.001206427,0.00004211674,0.00077734044,0.000078646604,0.0000056623585,0.0001611877,0.000041133313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973275,0.00007077637,0.0006691486,0.0010373443,0.00037860614,0.00051660335],"domain_scores_gemma":[0.99752146,0.000020934413,0.00040088827,0.0014108198,0.00045432185,0.0001915534],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030407045,0.0005845069,0.0005811373,0.00019410664,0.00009010663,0.00008228023,0.00048124822,0.00072808866,0.000043016924],"category_scores_gemma":[0.000026872793,0.00066689536,0.0002849099,0.00019774723,0.00010575864,0.000007876936,0.00060128013,0.0004436226,0.00002917654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002864371,0.00017282432,0.008396953,0.0011891392,0.00019764114,0.00001123818,0.0000054939474,0.0019176075,0.98768854,0.000041012663,0.00034971663,0.0000012176591],"study_design_scores_gemma":[0.00051606994,0.00015140817,0.01760179,0.00031215503,0.00011946965,8.2426425e-8,0.000004180308,0.00009207717,0.9802488,4.0295822e-7,0.00028706904,0.00066649937],"about_ca_topic_score_codex":0.000006439268,"about_ca_topic_score_gemma":0.0000015996047,"teacher_disagreement_score":0.03179873,"about_ca_system_score_codex":0.000079499456,"about_ca_system_score_gemma":0.0002634038,"threshold_uncertainty_score":0.99957824},"labels":[],"label_agreement":null},{"id":"W2941240433","doi":"10.1016/j.semcdb.2019.04.012","title":"Versatile and multifaceted CRISPR/Cas gene editing tool for plant research","year":2019,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; National Research Council Canada","funders":"National Research Council Canada","keywords":"CRISPR; Genome editing; Transcription activator-like effector nuclease; Biology; Zinc finger nuclease; Computational biology; Biotechnology; Gene; Genetics","score_opus":0.045409919465171686,"score_gpt":0.39745066311855853,"score_spread":0.35204074365338683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2941240433","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011585645,0.9865903,0.00021243296,0.000005661186,0.00037198444,0.00081215415,0.0001875501,0.0000067087494,0.00022751199],"genre_scores_gemma":[0.0015977164,0.9906659,0.0054730834,0.000018574208,0.00019568988,0.00015541837,0.0014086909,0.000036243975,0.0004486444],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984186,0.00007909314,0.00035859479,0.0006309354,0.000063397434,0.0004493326],"domain_scores_gemma":[0.9994929,0.00019697816,0.000066378794,0.00014777249,0.000031719414,0.00006427471],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005021211,0.00029047602,0.00057774683,0.00015760434,0.00008470213,0.000019730898,0.00014603882,0.0005153669,0.0000067197325],"category_scores_gemma":[0.00010752082,0.0002597664,0.00007031554,0.00009018657,0.00010601764,0.0000021832627,0.00035661762,0.00023801542,0.0000074727614],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006398831,0.000053051295,0.0007816976,0.008331993,0.00011080422,0.00001342299,0.00042204603,0.0000021705346,0.035128556,0.000010018871,0.003743969,0.9513383],"study_design_scores_gemma":[0.000512365,0.00022975284,0.000023318584,0.0009252674,0.000035156147,0.00009221691,0.0002739694,0.00001998876,0.019962244,0.000010547795,0.97753453,0.00038066995],"about_ca_topic_score_codex":0.0000130340695,"about_ca_topic_score_gemma":0.000011590533,"teacher_disagreement_score":0.9737905,"about_ca_system_score_codex":0.000048016092,"about_ca_system_score_gemma":0.00015124086,"threshold_uncertainty_score":0.99998546},"labels":[],"label_agreement":null},{"id":"W2941737830","doi":"10.1101/618413","title":"A broad-host-range CRISPRi toolkit for silencing gene expression in <i>Burkholderia</i>","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cystic Fibrosis Canada; Institut national de la recherche scientifique; Cystic Fibrosis Foundation","keywords":"Biology; Burkholderia; Gene silencing; Genetics; Genome editing; Computational biology; Cas9; Gene; Burkholderia cenocepacia; CRISPR; Bacteria","score_opus":0.010246030390137686,"score_gpt":0.25073016499057665,"score_spread":0.24048413460043896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2941737830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9328349,0.0061457455,0.057422474,0.000064149615,0.0015945879,0.0015179575,0.0003040681,0.000104125225,0.000011950527],"genre_scores_gemma":[0.981731,0.0008052894,0.015581496,0.00020983099,0.0009135172,0.00052317267,0.000004018164,0.00021094849,0.00002075043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99692833,0.00007104727,0.00061364943,0.0013728794,0.00026607778,0.00074801553],"domain_scores_gemma":[0.9977037,0.000037301357,0.0002466462,0.0015488334,0.00026093645,0.00020258437],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046526926,0.00065727753,0.000604364,0.00021170935,0.00008465475,0.00012703777,0.0006376695,0.000905119,0.000014128983],"category_scores_gemma":[0.0002222412,0.00074402546,0.000273645,0.00019247756,0.00004772639,0.000012087248,0.00067356706,0.00047581916,0.000017504623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000824185,0.00007861293,0.00375049,0.00052581145,0.00005581688,0.0000101292635,0.000012675922,0.002346405,0.9923622,0.000008458636,0.0007646029,0.0000023816197],"study_design_scores_gemma":[0.001074312,0.00011163127,0.015824698,0.0003954185,0.00005100079,3.9871285e-8,0.0000058624696,0.0005748352,0.9733716,7.037443e-7,0.007702916,0.00088696345],"about_ca_topic_score_codex":0.000032247382,"about_ca_topic_score_gemma":0.00000595795,"teacher_disagreement_score":0.048896037,"about_ca_system_score_codex":0.000112206384,"about_ca_system_score_gemma":0.00030019702,"threshold_uncertainty_score":0.99950105},"labels":[],"label_agreement":null},{"id":"W2944166269","doi":"10.1101/630236","title":"The Vertebrate Codex Gene Breaking Protein Trap Library For Genomic Discovery and Disease Modeling Applications","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Mayo Foundation for Medical Education and Research; National Human Genome Research Institute; Mayo Clinic","keywords":"Biology; Genetics; Forward genetics; Gene; Zebrafish; Insertional mutagenesis; Genetic screen; Gene knockdown; Phenotype; Locus (genetics); Positional cloning; Transposable element; Mutagenesis; Mutant","score_opus":0.007501791575728955,"score_gpt":0.2254073325198416,"score_spread":0.21790554094411266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944166269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6704501,0.010169092,0.31619534,0.00019801274,0.00023621258,0.0020485418,0.0006232071,0.00007705855,0.0000024236724],"genre_scores_gemma":[0.9923413,0.001144509,0.0042024804,0.000104807186,0.00058932457,0.0014211761,0.00000901258,0.00015592176,0.00003148104],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832,0.00003625565,0.00032345144,0.0008104076,0.000115564755,0.00039434925],"domain_scores_gemma":[0.99850106,0.000020350699,0.00013555687,0.0010363293,0.00008466215,0.000222063],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018946483,0.000375755,0.0002448055,0.000055485736,0.00024206963,0.0003578522,0.00042727622,0.0002562924,0.0000010685541],"category_scores_gemma":[0.000047109825,0.0003501004,0.00014556917,0.00007825502,0.00006495251,0.000016887645,0.000509204,0.00022764177,0.0000030520946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008294211,0.00003164103,0.0005489867,0.0003821449,0.00012518241,0.0000013755692,0.0000023474634,0.012664762,0.98564744,0.00039280145,0.00010899066,0.00001136154],"study_design_scores_gemma":[0.0011039667,0.000100791876,0.004847767,0.00030585052,0.0002776048,5.4490986e-8,0.000007008384,0.15549357,0.8095227,0.000058766986,0.026680369,0.0016015277],"about_ca_topic_score_codex":0.0000037018524,"about_ca_topic_score_gemma":8.331496e-7,"teacher_disagreement_score":0.32189116,"about_ca_system_score_codex":0.000026151765,"about_ca_system_score_gemma":0.0004761514,"threshold_uncertainty_score":0.9998951},"labels":[],"label_agreement":null},{"id":"W2944275418","doi":"10.1186/s13104-019-4207-2","title":"Mutagenesis of seed storage protein genes in Soybean using CRISPR/Cas9","year":2019,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Recruitment Program of Global Experts","keywords":"Gene; Storage protein; CRISPR; Biology; Mutagenesis; Transformation (genetics); Mutant; Genome editing; Agrobacterium; Cas9; Biotechnology; Genetics","score_opus":0.07373390637663106,"score_gpt":0.41482295442151107,"score_spread":0.34108904804488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944275418","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99109095,0.001922405,0.006201702,0.000019461566,0.000052059317,0.000497036,0.000008566431,0.000006674079,0.00020111582],"genre_scores_gemma":[0.9960494,0.00003340318,0.003454674,0.0000045244174,0.00010420962,0.000022523442,0.000012700523,0.00002902207,0.00028955034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986558,0.00014839243,0.00021086166,0.0003218469,0.00029338375,0.00036971935],"domain_scores_gemma":[0.99927473,0.00005946659,0.00003312025,0.00042746917,0.00013622576,0.000069013215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007669052,0.000118668264,0.00016768448,0.00018695382,0.000035929737,0.000019001836,0.0002288064,0.00012269468,0.000031271346],"category_scores_gemma":[0.00030592794,0.00011747216,0.00006921452,0.00025620728,0.000067673216,0.0000042293073,0.00019148942,0.00012650184,0.000013449143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005895729,0.000039062466,0.048298705,0.00016046173,0.000011055251,0.0000029238668,0.00005686685,0.005022482,0.9459793,0.00001551169,0.000011273722,0.00034339837],"study_design_scores_gemma":[0.00040130617,0.00016255546,0.021919446,0.000051725263,0.0000022023933,0.000002888632,0.00021441787,0.0041537583,0.97254896,0.000022728122,0.00037979355,0.0001401974],"about_ca_topic_score_codex":0.00034236588,"about_ca_topic_score_gemma":0.00014949386,"teacher_disagreement_score":0.02656968,"about_ca_system_score_codex":0.00002235853,"about_ca_system_score_gemma":0.00017703928,"threshold_uncertainty_score":0.47903755},"labels":[],"label_agreement":null},{"id":"W2944307723","doi":"10.1038/s41467-019-10079-2","title":"Building a global alliance of biofoundries","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":307,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council","keywords":"Alliance; Genetically engineered; Biotechnology; Business; Computer science; Data science; Biology; Political science; Genetics","score_opus":0.008059828732439104,"score_gpt":0.34325515451476313,"score_spread":0.335195325782324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944307723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94701785,0.038131554,0.0059152404,0.00073252525,0.00026568444,0.00019606511,0.000041582192,0.000020976318,0.0076785213],"genre_scores_gemma":[0.97158796,0.0006237284,0.027548762,0.00007914911,0.000022367298,0.0000048438433,0.000032034957,0.000005204535,0.00009592806],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99967927,0.000014057285,0.00008834254,0.00009318321,0.000049402403,0.00007572155],"domain_scores_gemma":[0.99895304,0.000011203655,0.00003179586,0.0009244112,0.00006018767,0.000019368623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005033572,0.000054023112,0.00006249949,0.0000081273065,0.000027892946,0.000005973256,0.0004544064,0.00012841019,0.000005389233],"category_scores_gemma":[0.000042647476,0.00005553941,0.000041316307,0.000094170755,0.00004335503,0.0000015354406,0.00020010938,0.00011408542,0.000005393334],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012945097,0.00005204415,0.039641857,0.000026861837,0.000057473542,9.181652e-8,0.000026857922,0.00036220922,0.9246033,0.031149663,0.0016716213,0.0023951035],"study_design_scores_gemma":[0.00044960892,0.00011479121,0.057374742,0.000049497678,0.000024363635,0.000012859577,0.00008353557,0.0005815731,0.24991056,0.000545519,0.69057536,0.00027760759],"about_ca_topic_score_codex":0.0000050310573,"about_ca_topic_score_gemma":0.00005745326,"teacher_disagreement_score":0.68890375,"about_ca_system_score_codex":0.0000069114835,"about_ca_system_score_gemma":0.000022879623,"threshold_uncertainty_score":0.22648315},"labels":[],"label_agreement":null},{"id":"W2944862599","doi":"10.1038/s41587-019-0145-8","title":"How bans on germline editing deprive patients with mitochondrial disease","year":2019,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Germline; Genome editing; Genetics; Biology; CRISPR; Gene","score_opus":0.002038368810961175,"score_gpt":0.21870754919247606,"score_spread":0.2166691803815149,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944862599","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07706668,0.004059515,0.007903691,0.89813656,0.008635962,0.0021360079,0.0013763885,0.00034549108,0.00033968815],"genre_scores_gemma":[0.36583248,0.00043234965,0.006230866,0.54551464,0.048690226,0.00022622541,0.021749489,0.0007274078,0.010596297],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99802715,0.000027766417,0.0001637597,0.00096513965,0.00029811036,0.00051806046],"domain_scores_gemma":[0.998614,0.000023565783,0.00014897808,0.0010379452,0.00011877282,0.00005670961],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.000026891801,0.00049329706,0.0003414281,0.00020461305,0.000055991808,0.0000399463,0.0005017068,0.0053254566,0.00000801393],"category_scores_gemma":[0.00024758678,0.00041130887,0.00014993017,0.00012608155,0.0001145589,0.0000025881775,0.0001827263,0.003210024,0.000014827391],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022874198,0.00006291797,0.0007068802,0.00015271855,0.00021593261,0.00011685584,0.0000036631848,0.000061808416,0.017865721,0.000039409173,0.9785076,0.0020377776],"study_design_scores_gemma":[0.0009557239,0.00050847715,0.00045500477,0.00007606928,0.000074060874,0.0000056438153,0.0000032234902,0.000010513841,0.038986985,0.000012679051,0.95841515,0.0004964817],"about_ca_topic_score_codex":0.0000012299047,"about_ca_topic_score_gemma":0.0000054700586,"teacher_disagreement_score":0.3526219,"about_ca_system_score_codex":0.00003132064,"about_ca_system_score_gemma":0.00007076405,"threshold_uncertainty_score":0.9998339},"labels":[],"label_agreement":null},{"id":"W2945057570","doi":"10.1089/hum.2019.074","title":"<i>In Vitro</i> Validation of a CRISPR-Mediated CFTR Correction Strategy for Preclinical Translation in Pigs","year":2019,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Biology; Viral vector; Genome editing; Genetic enhancement; Electroporation; Gene targeting; Gene; Computational biology; Molecular biology; Cell biology; Genetics; Recombinant DNA","score_opus":0.0329318824274944,"score_gpt":0.3606802611280246,"score_spread":0.3277483787005302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945057570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935166,0.00042582833,0.0052306945,0.000020414462,0.00016743051,0.0005002204,0.0000102521235,0.000006083291,0.00012242609],"genre_scores_gemma":[0.9989164,0.00013943754,0.00032255126,0.00004006008,0.00008829776,0.00004241015,0.0003062984,0.00001694073,0.00012759786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993196,0.00003523567,0.00026207988,0.00019899756,0.000060121907,0.00012396109],"domain_scores_gemma":[0.9997227,0.000027301669,0.000053324202,0.00014619324,0.000031698797,0.000018752913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019949756,0.00008995988,0.00013331862,0.000060701255,0.000011087524,0.000005737624,0.00006306768,0.000116803596,0.00002372389],"category_scores_gemma":[0.0000100111265,0.00009486814,0.000059342845,0.00006959347,0.000011537145,0.0000045819015,0.0000047545714,0.000053084623,0.0000018766539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035333337,0.00007450176,0.0011931563,0.000014240304,0.000009971962,1.4816672e-7,0.00012401308,0.005654645,0.9901455,0.0000031363813,0.00006189027,0.0023654397],"study_design_scores_gemma":[0.0020921882,0.00047255954,0.005333992,0.000009588806,0.0000025624975,0.0000011000136,0.000033929504,0.0016745783,0.9893811,0.000063266845,0.0008289214,0.000106255],"about_ca_topic_score_codex":0.000022857465,"about_ca_topic_score_gemma":0.00003537789,"teacher_disagreement_score":0.005399756,"about_ca_system_score_codex":0.000008498622,"about_ca_system_score_gemma":0.000022235283,"threshold_uncertainty_score":0.38686106},"labels":[],"label_agreement":null},{"id":"W2945437644","doi":"10.1038/s41591-019-0467-6","title":"Molecular scissors cut in on stem cells","year":2019,"lang":"en","type":"article","venue":"Nature Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"World Federation of Science Journalists","funders":"","keywords":"Stem cell; Biology; Genome editing; Medicine; Gene; Computational biology; Bioinformatics; Genetics; CRISPR","score_opus":0.0028041742981229313,"score_gpt":0.275426588624695,"score_spread":0.2726224143265721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945437644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909674,0.0030056653,0.00021624572,0.0004255177,0.0005951208,0.00016294693,0.0000018915619,0.000009315967,0.0046159304],"genre_scores_gemma":[0.99762225,0.000087998385,0.00004858678,0.00096839434,0.00018401511,0.000004061931,0.000016116388,0.000018266608,0.0010503219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992521,0.000016927588,0.0001231142,0.00026414954,0.00016494043,0.00017881529],"domain_scores_gemma":[0.99958485,0.000010535015,0.000022017393,0.00030095578,0.000025005385,0.000056651137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013853716,0.00012418875,0.00014147279,0.00007730353,0.000008522647,0.000002828776,0.00013350724,0.00024657775,0.00003676365],"category_scores_gemma":[0.00001942201,0.00009995234,0.00003397004,0.000119463075,0.000022320168,7.69131e-7,0.00003129132,0.00028477094,0.00002955131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035229074,0.000016369717,0.0011085398,0.000023388659,0.000010866211,0.000013710134,0.00003695576,0.0016452704,0.99397653,0.00013376425,0.0015592437,0.0014401296],"study_design_scores_gemma":[0.0008498742,0.00035860273,0.0015818559,0.000074282434,0.0000061595365,0.0000052743094,0.00006015558,0.00014291391,0.95623,0.000014986329,0.040548064,0.00012784223],"about_ca_topic_score_codex":0.000004629063,"about_ca_topic_score_gemma":0.000008243528,"teacher_disagreement_score":0.03898882,"about_ca_system_score_codex":0.000011354832,"about_ca_system_score_gemma":0.000014421302,"threshold_uncertainty_score":0.40759382},"labels":[],"label_agreement":null},{"id":"W2945543852","doi":"10.20529/ijme.2019.016","title":"Starting the conversation: CRISPR’s role in India","year":2019,"lang":"en","type":"article","venue":"Indian Journal of Medical Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NeuroDevNet; University Health Network; University of British Columbia","funders":"","keywords":"CRISPR; Sociocultural evolution; Conversation; Context (archaeology); Business; Internet privacy; Political science; Public relations; Sociology; Biology; Computer science; Law; Gene; Genetics; Communication","score_opus":0.009841698132956475,"score_gpt":0.32928258245624825,"score_spread":0.31944088432329176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945543852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9847736,0.0013989685,0.0017727097,0.011135035,0.0005259149,0.0000685653,0.0000012245044,0.0000018403185,0.00032218968],"genre_scores_gemma":[0.99732655,0.0003741391,0.00013892117,0.0017713832,0.00035106242,7.3843944e-7,0.000002094758,0.000008264997,0.00002682981],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987519,0.00010535079,0.00030332216,0.0000807462,0.0006088429,0.00014987576],"domain_scores_gemma":[0.99940956,0.0001472856,0.00011072657,0.00012816842,0.00008729603,0.000116995085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025529878,0.000066698754,0.000106261075,0.00004787698,0.00002536304,0.000016484091,0.00030015688,0.0003347475,0.00013107719],"category_scores_gemma":[0.0014261921,0.000047859274,0.000059210313,0.00007787103,0.00006256141,0.0000034224104,0.000052311265,0.0010967631,0.0000100288435],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086274266,0.0006440255,0.4482251,0.0012012541,0.0009718774,0.0021322912,0.15612112,0.018714802,0.2487765,0.004729286,0.017043889,0.1005771],"study_design_scores_gemma":[0.017691562,0.0041660275,0.21186626,0.0030361316,0.00015609093,0.0023935419,0.08183226,0.0053821364,0.40089846,0.0077727106,0.26273733,0.002067523],"about_ca_topic_score_codex":0.000009850957,"about_ca_topic_score_gemma":0.000032909422,"teacher_disagreement_score":0.24569343,"about_ca_system_score_codex":0.000011804646,"about_ca_system_score_gemma":0.0005353694,"threshold_uncertainty_score":0.47649506},"labels":[],"label_agreement":null},{"id":"W2945712785","doi":"10.3390/plants8050128","title":"Mutation Breeding in Tomato: Advances, Applicability and Challenges","year":2019,"lang":"en","type":"review","venue":"Plants","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Mutagenesis; Genome editing; Genome; Biology; Computational biology; Biotechnology; Insertional mutagenesis; Molecular breeding; Mutation breeding; Mutation; Identification (biology); Whole genome sequencing; Trait; Forward genetics; Genetics; Computer science; Mutant; Gene","score_opus":0.0433873332759436,"score_gpt":0.36059789105748474,"score_spread":0.31721055778154117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945712785","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006996569,0.9984588,0.00009071027,0.000003800642,0.00009378237,0.00027484325,0.00003105884,0.000006767368,0.00034055611],"genre_scores_gemma":[0.0010803156,0.99850124,0.0001118714,0.000003213333,0.000083058025,0.00003951009,0.00014295329,0.000016739576,0.0000211091],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993141,0.000019232664,0.00017281127,0.00031108412,0.00005013862,0.0001325778],"domain_scores_gemma":[0.99972427,0.000022191236,0.00004934156,0.00016741466,0.000006067963,0.00003069375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010552127,0.00015458913,0.00036716627,0.0000385818,0.00000955793,0.0000072159655,0.00007665496,0.00018038439,0.0000017142875],"category_scores_gemma":[0.000019047691,0.00014264244,0.00004610105,0.000025459372,0.000011263751,0.000001583974,0.0000566984,0.00008039226,0.0000067603355],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000022341187,0.00000766337,0.000014169495,0.008632399,0.000013351477,0.0000021291517,0.000013549267,0.000008771922,0.00005433693,0.0000052621776,0.0000107127635,0.99123544],"study_design_scores_gemma":[0.000112925794,0.000036234702,0.000073666786,0.0011367585,0.000026732725,0.00006443249,0.000019131634,0.000019953295,0.00009634601,0.000008803226,0.9982213,0.00018371575],"about_ca_topic_score_codex":0.000002672918,"about_ca_topic_score_gemma":0.000025504827,"teacher_disagreement_score":0.9982106,"about_ca_system_score_codex":0.000009315155,"about_ca_system_score_gemma":0.0000206541,"threshold_uncertainty_score":0.581679},"labels":[],"label_agreement":null},{"id":"W2946009223","doi":"10.1101/057802","title":"Genome-wide specificity profiles of CRISPR-Cas Cpf1 nucleases in human cells","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Trans-activating crRNA; Biology; Genome editing; Computational biology; Cas9; Genome; RNA; Guide RNA; Genetics; Genome engineering; Gene","score_opus":0.009972333570783394,"score_gpt":0.2460241019151595,"score_spread":0.2360517683443761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946009223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989486,0.001886669,0.007092512,0.000041966305,0.00047037785,0.00058194494,0.00033857088,0.00005975006,0.000042251668],"genre_scores_gemma":[0.99740064,0.0005142889,0.0012851779,0.000039976967,0.00053188263,0.000078403566,0.0000015223011,0.00013129703,0.000016782886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99753463,0.00008329379,0.0006533668,0.0009548987,0.0002457557,0.00052808],"domain_scores_gemma":[0.99794024,0.00002457824,0.000302539,0.0013024495,0.00024682863,0.00018338992],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003303158,0.0005218864,0.00055316655,0.00022635276,0.000062230836,0.000049144943,0.0006018409,0.0005730571,0.00005885559],"category_scores_gemma":[0.000113215814,0.0005320683,0.00020951508,0.0001710107,0.00014550422,0.000006376196,0.00062210223,0.00034028935,0.000016657486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028922885,0.00012626096,0.014214104,0.00036113115,0.00008011698,0.000018595156,0.000006378113,0.00024677793,0.9846511,0.000054696757,0.00021079145,0.0000011378818],"study_design_scores_gemma":[0.00037204046,0.00007529469,0.13119853,0.00021257332,0.00003366268,1.1362695e-8,0.0000033867937,0.000012773499,0.86380714,0.0000028261015,0.0037421223,0.00053962873],"about_ca_topic_score_codex":0.000035189554,"about_ca_topic_score_gemma":0.0000080164355,"teacher_disagreement_score":0.12084394,"about_ca_system_score_codex":0.00008906793,"about_ca_system_score_gemma":0.00021322625,"threshold_uncertainty_score":0.99971306},"labels":[],"label_agreement":null},{"id":"W2947089828","doi":"10.1186/s13059-019-1678-3","title":"Linking CRISPR-Cas9 interference in cassava to the evolution of editing-resistant geminiviruses","year":2019,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Eidgenössische Technische Hochschule Zürich; European Commission","keywords":"CRISPR; Biology; Cas9; Genetics; Virus; Genome editing; Nicotiana benthamiana; Virology; Genome; Geminiviridae; DNA virus; Plant virus; Computational biology; Gene; Begomovirus","score_opus":0.010497821005578547,"score_gpt":0.29838630122279614,"score_spread":0.2878884802172176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947089828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97514176,0.001820971,0.02157385,0.00012049793,0.00042613517,0.00019954205,0.00002520365,0.000006344395,0.00068569207],"genre_scores_gemma":[0.9991418,0.0000467319,0.00031180866,0.00008831137,0.00024135322,0.000013697504,0.000026312488,0.000010618021,0.000119363016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992116,0.000043640826,0.00021843328,0.00025812775,0.000038457463,0.00022972883],"domain_scores_gemma":[0.99954236,0.000021343789,0.00005275356,0.00030767792,0.000043951997,0.000031897962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022756497,0.00010550128,0.00014192278,0.00007067364,0.000020096813,0.000005247037,0.00024779697,0.00011652554,0.000023996283],"category_scores_gemma":[0.000064671374,0.000083684914,0.000044454297,0.00011049344,0.00003519016,0.0000013529022,0.0001714367,0.000083294166,0.000028316936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043171774,0.000011848002,0.022144359,0.000019032157,0.000012862947,5.3349646e-7,0.00015933091,0.0013646123,0.9751535,0.00019464511,0.00005241784,0.000843703],"study_design_scores_gemma":[0.0013851589,0.002982154,0.20468532,0.00016093683,0.00003847109,0.00003613514,0.0024004932,0.00070850947,0.6047214,0.00044074276,0.1815424,0.00089826755],"about_ca_topic_score_codex":0.00012868416,"about_ca_topic_score_gemma":0.0004015858,"teacher_disagreement_score":0.37043208,"about_ca_system_score_codex":0.00003319856,"about_ca_system_score_gemma":0.00004178195,"threshold_uncertainty_score":0.34125715},"labels":[],"label_agreement":null},{"id":"W2947212862","doi":"10.7554/elife.47900","title":"Reality check for transposon enhancers","year":2019,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"","keywords":"Reality check; Transposable element; Enhancer; Computational biology; Biology; Genetics; Genome; Gene; Transcription factor","score_opus":0.008432916332853967,"score_gpt":0.31761374520564345,"score_spread":0.30918082887278947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947212862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9521353,0.00054506224,0.04452653,0.00013751275,0.0002786971,0.00022689655,0.000021506961,0.000014180917,0.0021143076],"genre_scores_gemma":[0.9970941,0.000088772016,0.0008586464,0.00015424204,0.00020317822,0.000018825549,0.00006685193,0.000012663333,0.0015027391],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995722,0.000004610909,0.0000786221,0.0001623378,0.000053098523,0.00012909803],"domain_scores_gemma":[0.99974304,0.0000041380154,0.0000130987055,0.00017725014,0.00002567379,0.000036800044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007883375,0.00006464299,0.00006686042,0.00000836954,0.000015007545,0.0000048526476,0.000068211775,0.000062735395,0.000024505827],"category_scores_gemma":[0.0000125796805,0.00006467067,0.000062955034,0.000020491758,0.000007856268,7.4176364e-7,0.000009300496,0.000025503463,0.00001635031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040616032,0.000009289639,0.000592018,0.00003337171,0.000016864216,9.146461e-8,0.000034448207,0.00053421216,0.99435604,0.000041976153,0.0029471195,0.0013939699],"study_design_scores_gemma":[0.00031061773,0.000103253675,0.0019327081,0.000004311311,0.000005189917,7.1635316e-7,0.00002032963,0.00017033504,0.8323036,0.000007030677,0.16505435,0.000087595756],"about_ca_topic_score_codex":0.000006102291,"about_ca_topic_score_gemma":0.000010884903,"teacher_disagreement_score":0.16210724,"about_ca_system_score_codex":0.0000048020506,"about_ca_system_score_gemma":0.000018824085,"threshold_uncertainty_score":0.26371935},"labels":[],"label_agreement":null},{"id":"W2948582879","doi":"10.1093/nar/gkz269","title":"Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system","year":2019,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Structural Genomics Consortium; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Biology; CRISPR; Effector; RNA; RNase P; Computational biology; Cell biology; Genetics; Gene","score_opus":0.0162793713809626,"score_gpt":0.3311758770190848,"score_spread":0.3148965056381222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948582879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948604,0.0021643506,0.000019992876,0.00017184814,0.00011804177,0.00071195216,0.0000014920751,0.00000590047,0.0019460025],"genre_scores_gemma":[0.99938524,0.000027515405,0.000030570474,0.000031999025,0.00012413652,0.00003649983,0.0000035358485,0.000020308024,0.00034017398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844664,0.00032487622,0.00018936401,0.00025043846,0.00047950097,0.00030916635],"domain_scores_gemma":[0.9988591,0.000035771925,0.0000372699,0.00088330643,0.00014976284,0.00003477329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072577165,0.00011508292,0.000115775496,0.00005397479,0.00014458454,0.000039386035,0.0010263512,0.0001334264,0.000018635636],"category_scores_gemma":[0.0000979835,0.000057376677,0.00006611064,0.00034547385,0.00015597776,0.000005806573,0.0003924144,0.00039427791,0.000019977739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048979808,0.000014334887,0.0059299315,0.00009583776,0.000023641702,0.0000011518274,0.0023864845,0.0006452541,0.9880407,0.0011385988,0.00014871187,0.0015263843],"study_design_scores_gemma":[0.00050465367,0.00028813825,0.11535732,0.0000992386,0.000008658107,0.000011396419,0.007848626,0.0069137174,0.8553722,0.00043454944,0.012954589,0.00020689497],"about_ca_topic_score_codex":0.00018106682,"about_ca_topic_score_gemma":0.000111245114,"teacher_disagreement_score":0.13266847,"about_ca_system_score_codex":0.000039390703,"about_ca_system_score_gemma":0.000098590564,"threshold_uncertainty_score":0.2339753},"labels":[],"label_agreement":null},{"id":"W2948909630","doi":"10.1101/661140","title":"Essential gene networks in acute myeloid leukemia identified using a <i>microRNA</i> -knockout CRISPR library screen","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Leslie Dan Faculty of Pharmacy, University of Toronto; Natural Sciences and Engineering Research Council of Canada; Leukemia and Lymphoma Society of Canada; University of Toronto; Leukemia and Lymphoma Society","keywords":"microRNA; Myeloid leukemia; XIAP; Biology; Signal transduction; Computational biology; Gene; Cancer research; Cell biology; Apoptosis; Genetics; Programmed cell death","score_opus":0.00706652255185521,"score_gpt":0.2377725549698951,"score_spread":0.23070603241803989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948909630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92682105,0.005765802,0.06422104,0.000037328704,0.0019149235,0.0008051923,0.00027962576,0.00014119076,0.000013817942],"genre_scores_gemma":[0.9887244,0.0017568265,0.0074033155,0.00025577666,0.001426215,0.00006736899,0.000017236553,0.0003069182,0.00004190876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996351,0.0001270207,0.00077794236,0.0015284263,0.00030032612,0.0009152705],"domain_scores_gemma":[0.99748534,0.000017468647,0.00034315683,0.0017302257,0.00014903021,0.00027475183],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003371002,0.0008138142,0.00072511367,0.0002999417,0.0001048211,0.00031429323,0.00093621097,0.0012167939,0.000032346426],"category_scores_gemma":[0.000040589228,0.0009837357,0.00032014152,0.00040266803,0.00009866683,0.00002887741,0.0016116324,0.00092538266,0.000028181126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009697638,0.000047740083,0.0044253366,0.00016211164,0.0002963232,0.00007833355,0.000004448282,0.03921926,0.954766,0.0000097767215,0.00089093926,0.0000027647518],"study_design_scores_gemma":[0.00092111045,0.000047484944,0.016931064,0.00029444927,0.00019731946,2.6673473e-7,0.0000022391084,0.010386691,0.9674623,5.813799e-7,0.002598999,0.0011574948],"about_ca_topic_score_codex":0.000104152205,"about_ca_topic_score_gemma":0.000007660737,"teacher_disagreement_score":0.061903354,"about_ca_system_score_codex":0.00016128496,"about_ca_system_score_gemma":0.00088322704,"threshold_uncertainty_score":0.9992613},"labels":[],"label_agreement":null},{"id":"W2949033967","doi":"10.1038/s41467-019-10577-3","title":"Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Chinese Academy of Sciences; National Natural Science Foundation of China-Yunnan Joint Fund; Canadian Light Source; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Natural Science Foundation of China; National Institutes of Health; Government of Canada; Salt Science Research Foundation; Ministry of Science and Technology of the People's Republic of China; Foundation for the National Institutes of Health","keywords":"CRISPR; Ribonucleoprotein; Genome editing; Cas9; Trans-activating crRNA; Computational biology; Biology; Genetics; RNA; Gene","score_opus":0.010903407870956915,"score_gpt":0.3220277338456019,"score_spread":0.311124325974645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949033967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975921,0.010051881,0.005945432,0.0013811069,0.00016774356,0.0005129995,0.000178882,0.0000414633,0.0057995096],"genre_scores_gemma":[0.9935135,0.0006522213,0.0044297716,0.00024767368,0.000039774943,0.000018965247,0.0008633188,0.000025825153,0.00020890888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918926,0.00006188447,0.00023527068,0.00021396426,0.0001293052,0.00017033082],"domain_scores_gemma":[0.9981576,0.00002662312,0.00009223745,0.0014999864,0.00017142724,0.000052081035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014417172,0.00013784564,0.00016459367,0.000050066206,0.00007836837,0.000018073535,0.00050850445,0.00030744632,0.000027874612],"category_scores_gemma":[0.00007126201,0.0001462158,0.000091054666,0.00015248681,0.00006811771,0.000006339195,0.0003184482,0.00035496042,0.000022267224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000074029185,0.00008563762,0.0015034986,0.000023200733,0.000030353927,1.2197032e-7,0.000037608912,0.00004913679,0.9820703,0.00041082237,0.0152583085,0.0005235774],"study_design_scores_gemma":[0.00044817917,0.00010488267,0.010028589,0.00002889658,0.000021699694,0.0000061980268,0.000101201906,0.0006150536,0.79266924,0.00003136084,0.19572729,0.00021739845],"about_ca_topic_score_codex":0.000024842773,"about_ca_topic_score_gemma":0.000060824987,"teacher_disagreement_score":0.18940108,"about_ca_system_score_codex":0.000011836557,"about_ca_system_score_gemma":0.000028666977,"threshold_uncertainty_score":0.5962507},"labels":[],"label_agreement":null},{"id":"W2949222337","doi":"10.1002/bit.27084","title":"Construction of a sensitive pyrogen‐testing cell model by site‐specific knock‐in of multiple genes","year":2019,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"TLR4; CD14; Chemistry; Cell biology; Molecular biology; Biology; Signal transduction; Flow cytometry","score_opus":0.0050659571387995424,"score_gpt":0.207681418721801,"score_spread":0.20261546158300145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949222337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9710141,0.0033588966,0.02534953,0.00001677439,0.0000546477,0.00011272427,0.000028356098,0.000019980576,0.000045014243],"genre_scores_gemma":[0.9841129,0.0005436785,0.015279961,0.0000028744653,0.000011472847,0.0000028915936,0.000015788966,0.000013118531,0.000017315979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993844,0.0000055524442,0.00019069877,0.00022230395,0.00004047422,0.000156574],"domain_scores_gemma":[0.999717,0.000014437052,0.000052257343,0.00016401192,0.000030688414,0.000021621207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006230051,0.000119266,0.0001692399,0.000105000414,0.000011201069,0.0000021409464,0.00005941711,0.00027090893,0.0000010597788],"category_scores_gemma":[0.000014753934,0.00012785134,0.00003108218,0.00012399378,0.00007552648,0.0000023102812,0.00006778084,0.00008721567,6.898402e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016636437,0.000015970269,0.008355019,0.00007227218,0.0000119494225,6.216311e-7,0.000019879704,0.0139854085,0.97559774,0.00005168658,0.0000068143568,0.0018660239],"study_design_scores_gemma":[0.0003591041,0.00010474316,0.00047556602,0.000026402296,0.000005797247,0.000015610067,0.00008807667,0.05042908,0.94812787,0.0000054288907,0.0002404567,0.00012185897],"about_ca_topic_score_codex":0.000010462854,"about_ca_topic_score_gemma":0.000004210067,"teacher_disagreement_score":0.03644367,"about_ca_system_score_codex":0.000005495739,"about_ca_system_score_gemma":0.000010326711,"threshold_uncertainty_score":0.5213626},"labels":[],"label_agreement":null},{"id":"W2949460184","doi":"10.1101/003327","title":"Measuring error rates in genomic perturbation screens: gold standards for human functional genomics","year":2014,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Princess Margaret Cancer Centre; University Health Network; Ontario Institute for Cancer Research; University of Toronto","funders":"Ontario Institute for Cancer Research; Ontario Ministry of Research and Innovation; Canadian Institute for Advanced Research","keywords":"CRISPR; RNA interference; Computational biology; Biology; Gene; Functional genomics; Genomics; Gene knockdown; Computer science; Genome; Genetics; RNA","score_opus":0.02162495210871693,"score_gpt":0.2647788304067884,"score_spread":0.24315387829807147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949460184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92071676,0.002058949,0.07521443,0.00005608615,0.000692269,0.0007871485,0.00039575723,0.000066222034,0.000012352845],"genre_scores_gemma":[0.993662,0.0001563001,0.004411363,0.00010004463,0.0011811432,0.00029580222,0.000013143907,0.00015499887,0.00002518538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977181,0.00006242533,0.0005258587,0.0009410133,0.00026234105,0.00049026957],"domain_scores_gemma":[0.9983549,0.000023013605,0.00021761016,0.00078603957,0.00047200624,0.000146417],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008904515,0.00048301634,0.00041994484,0.0002092974,0.00011614064,0.000117190975,0.00034660866,0.000571082,0.000010524418],"category_scores_gemma":[0.00022087582,0.0005770105,0.00019765756,0.00010540445,0.00005997717,0.00000691655,0.0003079172,0.00034710809,0.0000042470915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000073544456,0.000041200634,0.001985062,0.00029889707,0.00010072626,0.0000016786584,0.000005312982,0.012198053,0.9847281,0.00016533212,0.00039802387,0.0000040744053],"study_design_scores_gemma":[0.0015286066,0.00017277872,0.08389198,0.00023808381,0.00009928227,4.5808076e-8,0.0000060552916,0.00418156,0.8832274,0.000014689205,0.025477367,0.0011621254],"about_ca_topic_score_codex":0.000023519859,"about_ca_topic_score_gemma":0.000026146865,"teacher_disagreement_score":0.10150067,"about_ca_system_score_codex":0.00032736792,"about_ca_system_score_gemma":0.00051283895,"threshold_uncertainty_score":0.9996681},"labels":[],"label_agreement":null},{"id":"W2949471222","doi":"10.1002/humu.23842","title":"The spectrum of <i>BRCA1</i> and <i>BRCA2</i> pathogenic sequence variants in Middle Eastern, North African, and South European countries","year":2019,"lang":"en","type":"article","venue":"Human Mutation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"European Social Fund; National Cancer Institute; Medical Research Council; Ministero dello Sviluppo Economico; National Health and Medical Research Council; Dr. Ralph and Marian Falk Medical Research Trust; Cancer Research UK; Dipartimenti di Eccellenza; National Institutes of Health; Ovarian Cancer Research Fund; University of Chicago; National Breast Cancer Foundation; Ministère du Développement Économique, de l’Innovation et de l’Exportation; Jonsson Comprehensive Cancer Center; Canadian Institutes of Health Research; Associazione Italiana per la Ricerca sul Cancro; European Commission; Breast Cancer Research Foundation","keywords":"Biology; Genotyping; Demography; Population; Inbreeding; Genetics; Consanguinity; Founder effect; Allele; Haplotype; Gene; Genotype","score_opus":0.010609336617678926,"score_gpt":0.2396964232879168,"score_spread":0.22908708667023786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949471222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981088,0.00082112494,0.00030046728,0.000024901365,0.00003586175,0.000119787226,0.000010241535,0.0000038263493,0.0005749762],"genre_scores_gemma":[0.9996201,0.00009663388,0.000048678176,0.00002825298,0.000030402189,0.0000026343598,0.000022821625,0.000010467453,0.00014001102],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995014,0.000035891917,0.00013403627,0.00016102578,0.000060337363,0.00010728724],"domain_scores_gemma":[0.9997638,0.000008848094,0.000052299005,0.00013328885,0.00001874952,0.000023017385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014420357,0.000072801304,0.00006761283,0.000020260508,0.00004378796,0.000022759577,0.000058794798,0.000022828457,0.0000023876748],"category_scores_gemma":[0.000010467514,0.00006219038,0.000013329541,0.000038326754,0.00005328018,0.0000036980143,0.000042047726,0.000037841983,0.0000033416343],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009509448,0.000029422403,0.24565089,0.0001868829,0.000052944943,0.000015680884,0.004940883,0.0013170049,0.744331,0.00075419905,0.00002641873,0.002599606],"study_design_scores_gemma":[0.0012409835,0.00037881138,0.9616782,0.00005427565,0.000024463126,0.00003145659,0.0010690505,0.0009015082,0.032661576,0.00021040697,0.0014708966,0.00027835515],"about_ca_topic_score_codex":0.000013118301,"about_ca_topic_score_gemma":0.00017122371,"teacher_disagreement_score":0.7160273,"about_ca_system_score_codex":0.000004178175,"about_ca_system_score_gemma":0.00001113638,"threshold_uncertainty_score":0.25360504},"labels":[],"label_agreement":null},{"id":"W2949522556","doi":"10.1242/dmm.036517","title":"CRISPR-Cas9 human gene replacement and phenomic characterization in <i>Caenorhabditis elegans</i> to understand the functional conservation of human genes and decipher variants of uncertain significance","year":2018,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Genetics; Gene; Caenorhabditis elegans; CRISPR; Computational biology; PTEN; Genome; Phenotype; Copy-number variation; PI3K/AKT/mTOR pathway","score_opus":0.021401158976181476,"score_gpt":0.2791803606631287,"score_spread":0.2577792016869472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949522556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.66109234,0.00014487853,0.3383921,0.00005820221,0.000031664902,0.00019636507,0.000071175666,0.0000026373266,0.000010617633],"genre_scores_gemma":[0.9988901,0.00006189041,0.0005696623,0.00017298096,0.000057004196,0.000024712463,0.0001696716,0.00001469243,0.00003925867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992669,0.000033322503,0.00021448621,0.00025938833,0.00010919139,0.00011669698],"domain_scores_gemma":[0.99958265,0.0000065410877,0.0000702424,0.0001955485,0.000077596844,0.00006741873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015030788,0.000108165186,0.00011174021,0.000039436538,0.00007593774,0.000012680214,0.00006122748,0.000043044314,0.000011371481],"category_scores_gemma":[0.0000074006775,0.00010124496,0.000020358777,0.000061099585,0.00005995448,0.000008146738,0.000053667565,0.000023895082,1.4582145e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013637633,0.000034283257,0.00042864966,0.000032119326,0.000020270883,6.1653196e-7,0.00018744088,0.0011266886,0.99421537,0.003592741,0.000020947078,0.00020448864],"study_design_scores_gemma":[0.0009882473,0.00044195977,0.047742132,0.00005097094,0.000059280843,0.0000027636522,0.0003475067,0.01170637,0.9309462,0.0074272715,0.00005365161,0.00023368602],"about_ca_topic_score_codex":0.000055648125,"about_ca_topic_score_gemma":0.00008209942,"teacher_disagreement_score":0.33782247,"about_ca_system_score_codex":0.000013380768,"about_ca_system_score_gemma":0.000035306963,"threshold_uncertainty_score":0.41286495},"labels":[],"label_agreement":null},{"id":"W2949593109","doi":"10.1371/journal.pgen.1007676","title":"3 minutes to precisely measure morphogen concentration","year":2018,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Agence Nationale de la Recherche; Ontario Trillium Foundation; Infrastructures en Biologie Santé et Agronomie; Université de Recherche Paris Sciences et Lettres; Mitacs; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Association pour la Recherche sur le Cancer","keywords":"Morphogen; Drosophila embryogenesis; Biology; Mitosis; Transcription factor; Cell biology; Transcription (linguistics); Genetics; Gap gene; Embryo; Embryogenesis; Gene","score_opus":0.015351846366029306,"score_gpt":0.2783130338514972,"score_spread":0.2629611874854679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949593109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806371,0.0015160732,0.015134126,0.00013757964,0.00025709768,0.00029443385,0.000022281114,0.000026033333,0.0019752828],"genre_scores_gemma":[0.99280727,0.00006361941,0.00538671,0.00030376285,0.0008944341,0.000022490913,0.000038376726,0.000028913113,0.00045440387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914116,0.000018162349,0.0001516194,0.00028611114,0.00015868324,0.00024425675],"domain_scores_gemma":[0.9993271,0.000005011252,0.000025199884,0.0003331937,0.00017340103,0.00013606934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006211755,0.00013666022,0.00009406458,0.00002159831,0.000056766035,0.000026405109,0.0001723261,0.00010090661,0.00004523425],"category_scores_gemma":[0.00006612771,0.00014292155,0.00004179065,0.000090264475,0.00004167035,0.0000012750482,0.00007265434,0.000038385235,0.00008987211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025735562,0.00002914061,0.0013285637,0.000007684084,0.00003717509,6.406351e-7,0.00012022674,0.0003089816,0.99035025,0.000006109042,0.0056244223,0.0021610728],"study_design_scores_gemma":[0.00019647749,0.0003587847,0.0008417903,0.000011316187,0.000023967146,0.0000046751834,0.000020769075,0.000989214,0.95765615,0.000014905223,0.039697625,0.00018430388],"about_ca_topic_score_codex":0.0000012221362,"about_ca_topic_score_gemma":0.000026729726,"teacher_disagreement_score":0.0340732,"about_ca_system_score_codex":0.000009658009,"about_ca_system_score_gemma":0.000041156305,"threshold_uncertainty_score":0.5828172},"labels":[],"label_agreement":null},{"id":"W2950109307","doi":"10.1016/j.ymthe.2018.08.010","title":"CRISPR-Induced Deletion with SaCas9 Restores Dystrophin Expression in Dystrophic Models In Vitro and In Vivo","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Mitacs","keywords":"Dystrophin; Exon; Duchenne muscular dystrophy; Frameshift mutation; Biology; CRISPR; Muscular dystrophy; Intron; Exon skipping; Molecular biology; Genetics; Gene; Alternative splicing","score_opus":0.00966042889023605,"score_gpt":0.271645979132171,"score_spread":0.26198555024193493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950109307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9834481,0.0014020391,0.014726821,0.00005834227,0.000034243083,0.00024004273,0.0000024375004,0.000008463966,0.0000795186],"genre_scores_gemma":[0.9975755,0.0002462751,0.0019071781,0.000120067285,0.000052999283,0.00004465912,0.000008841392,0.00003284731,0.000011581992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989612,0.00007207502,0.00019435315,0.00038441346,0.00012083606,0.00026712663],"domain_scores_gemma":[0.999612,0.000004626569,0.000033699635,0.00026876747,0.000029452951,0.000051502233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013701597,0.00018044768,0.00016462916,0.00015559261,0.000023047314,0.000017885188,0.00010979913,0.00014996156,0.000004232882],"category_scores_gemma":[0.000009485533,0.0001624238,0.000025140807,0.00015611848,0.000047112146,0.000007344092,0.00003861072,0.00012491847,6.2842116e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073784153,0.00004692719,0.0006646862,0.000007328264,0.0000062848558,0.000047157602,0.0001466276,0.002178491,0.9948415,0.000008100335,0.0000066476055,0.0013083824],"study_design_scores_gemma":[0.0017201662,0.0003720389,0.003129915,0.000052346935,0.0000016697504,0.0000147037545,0.00004378174,0.002144014,0.99195504,0.00013191788,0.00023284067,0.00020158527],"about_ca_topic_score_codex":0.000101090154,"about_ca_topic_score_gemma":0.0001972346,"teacher_disagreement_score":0.014127458,"about_ca_system_score_codex":0.00002430566,"about_ca_system_score_gemma":0.000026894033,"threshold_uncertainty_score":0.66234505},"labels":[],"label_agreement":null},{"id":"W2950112461","doi":"10.1101/381962","title":"Competition between mobile genetic elements drives optimization of a phage-encoded CRISPR-Cas system: Insights from a natural arms-race","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh; National Institute of Allergy and Infectious Diseases; Global Affairs Canada; Department for International Development; National Science Foundation; Department for International Development, UK Government; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"CRISPR; Vibrio cholerae; Biology; Mobile genetic elements; Genetics; Computational biology; Chromosome; Gene; Function (biology); Genome; Bacteria","score_opus":0.006264195228265843,"score_gpt":0.24235182343370537,"score_spread":0.23608762820543952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950112461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8315936,0.0039092507,0.16238505,0.0000080168875,0.0008613239,0.00076297054,0.00037904974,0.000095700714,0.0000050883705],"genre_scores_gemma":[0.9583436,0.00038086477,0.03989504,0.000019666342,0.0010244721,0.00018761048,0.0000324264,0.00011327227,0.0000030007434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973674,0.00014017444,0.00077279203,0.0009939565,0.00034607336,0.00037963016],"domain_scores_gemma":[0.99765337,0.000024663379,0.0005306744,0.0011111209,0.00050349795,0.00017668518],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015665175,0.0005475726,0.0006017946,0.000184475,0.00010169788,0.000085695756,0.00052220904,0.0005649042,0.000020815012],"category_scores_gemma":[0.00006254815,0.00060246,0.00018502254,0.00020028168,0.00012178294,0.000011862632,0.00048716637,0.00032070137,0.000012809271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035469802,0.0000798477,0.0056856396,0.0005331356,0.00037729152,0.00000870393,0.000034546913,0.015218884,0.97793174,0.000011198956,0.000080440695,0.0000030889146],"study_design_scores_gemma":[0.0007399406,0.00018125921,0.035777804,0.00050230214,0.0002705763,3.2582662e-8,0.000021602767,0.010462281,0.9508315,9.2644603e-7,0.0005234489,0.00068836764],"about_ca_topic_score_codex":0.000055574612,"about_ca_topic_score_gemma":0.0000051351403,"teacher_disagreement_score":0.1267501,"about_ca_system_score_codex":0.000110823574,"about_ca_system_score_gemma":0.00020386631,"threshold_uncertainty_score":0.99964267},"labels":[],"label_agreement":null},{"id":"W2950114027","doi":"10.1534/genetics.119.302089","title":"<i>beditor</i> : A Computational Workflow for Designing Libraries of Guide RNAs for CRISPR-Mediated Base Editing","year":2019,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Workflow; Genetics; Guide RNA; Computational biology; Base (topology); Genome editing; World Wide Web; Computer science; Database; Gene","score_opus":0.009182172179352601,"score_gpt":0.2785637669332133,"score_spread":0.2693815947538607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950114027","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11480434,0.0009904263,0.88219047,0.00011485007,0.0010056016,0.0005925482,0.00016858955,0.000019164903,0.000114020695],"genre_scores_gemma":[0.604504,0.00003600372,0.39256647,0.00017366046,0.0017319779,0.000074423704,0.00060806307,0.000053420143,0.00025202794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905497,0.000013330164,0.00029819418,0.0002600323,0.000117482225,0.00025600963],"domain_scores_gemma":[0.99930423,0.00014413096,0.0000954607,0.00019988953,0.00019049094,0.00006580146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016047717,0.00014571138,0.00016753351,0.000041993713,0.00004904639,0.000022907518,0.00015267631,0.0001269685,0.000009321433],"category_scores_gemma":[0.0001773765,0.00015940261,0.00011237829,0.000065376065,0.000034118355,0.0000035066096,0.00006107967,0.000042320942,0.0000024354717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000091765396,0.000040147548,0.0027503022,0.00023950648,0.000093955845,3.687811e-7,0.00011208308,0.115882106,0.8411025,0.000102389124,0.03623365,0.0033512749],"study_design_scores_gemma":[0.0014005086,0.00047705654,0.00039913293,0.00004593902,0.00004221488,0.0000034634963,0.00014960169,0.03512959,0.85869735,0.0005725063,0.1028055,0.0002771451],"about_ca_topic_score_codex":0.0000011243266,"about_ca_topic_score_gemma":0.0000035233431,"teacher_disagreement_score":0.48969963,"about_ca_system_score_codex":0.000006313157,"about_ca_system_score_gemma":0.00009919455,"threshold_uncertainty_score":0.650025},"labels":[],"label_agreement":null},{"id":"W2950338203","doi":"10.1101/gr.227124.117","title":"Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo","year":2018,"lang":"en","type":"article","venue":"Genome Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"H2020 European Research Council; Biotechnology and Biological Sciences Research Council; Medical Research Council Canada; Medical Research Council; University of Edinburgh","keywords":"Biology; Transcription factor; SOX2; Embryonic stem cell; Embryo; Gene; Cell biology; Genetics; In vivo; DNA; Computational biology","score_opus":0.04629733479405013,"score_gpt":0.37073888479935163,"score_spread":0.3244415500053015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950338203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975829,0.00073370134,0.0012479014,0.000010156843,0.000036335194,0.00013570563,0.000020184452,0.0000016799903,0.00023142605],"genre_scores_gemma":[0.9982592,0.00015694935,0.0014209935,0.0000039284355,0.00007971949,0.000004129009,0.000004081709,0.000010233582,0.000060782364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991874,0.00005104697,0.00015395584,0.00020464571,0.000120641635,0.00028227264],"domain_scores_gemma":[0.9997529,0.000009848853,0.000013126072,0.0001282541,0.0000507025,0.00004518579],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031057606,0.00006661983,0.000099490324,0.00018904558,0.000024786612,0.000009026781,0.00008299656,0.000082003724,0.000022144379],"category_scores_gemma":[0.000018118277,0.00007295148,0.00002169615,0.00020674097,0.000093287716,0.0000027501083,0.00005390472,0.00009708432,0.0000013228256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009486574,0.000017637192,0.002197994,0.000053969423,0.000005101989,0.000001997431,0.0005783417,0.000040199782,0.9964624,5.686909e-7,0.000005146934,0.0005417591],"study_design_scores_gemma":[0.0003218392,0.00007853694,0.01576703,0.00001738615,7.2063176e-7,0.0000025262268,0.00034061773,0.00047986896,0.9816815,0.000006542558,0.001228037,0.00007538685],"about_ca_topic_score_codex":0.00013224306,"about_ca_topic_score_gemma":0.000088754925,"teacher_disagreement_score":0.01478091,"about_ca_system_score_codex":0.000022698603,"about_ca_system_score_gemma":0.000041714073,"threshold_uncertainty_score":0.2974875},"labels":[],"label_agreement":null},{"id":"W2950781663","doi":"10.1101/112847","title":"A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Darwin Trust of Edinburgh; Cancer Research UK; Wellcome Trust","keywords":"Heterochromatin; Biology; Heterochromatin protein 1; Piwi-interacting RNA; Genetics; Chromatin; Germline; Euchromatin; Transposable element; Genome; RNA interference; Cell biology; Gene; RNA","score_opus":0.012143404849072796,"score_gpt":0.2422543821020777,"score_spread":0.2301109772530049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950781663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931422,0.0010427322,0.0033880926,0.000024038025,0.00023131668,0.0007205141,0.001397819,0.00003958836,0.000013723568],"genre_scores_gemma":[0.9910779,0.00028559257,0.008225343,0.00003251247,0.00016256416,0.00010258102,0.0000059660065,0.00010046459,0.0000070664955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99798226,0.000052379582,0.0004612911,0.0008769562,0.00022271709,0.00040440357],"domain_scores_gemma":[0.99753475,0.000018836867,0.0004426844,0.0012320656,0.000499082,0.00027256118],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022535038,0.00053457695,0.00055410014,0.00012907102,0.00012123227,0.00012137451,0.00045301975,0.0003572714,0.000005531473],"category_scores_gemma":[0.00018914916,0.0005094284,0.00007967984,0.00011320971,0.00012232344,0.000006356378,0.00065923814,0.00024297087,0.0000015426187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006963733,0.00008613299,0.015827648,0.00042841007,0.00022771284,0.000010608173,0.00003126546,0.00026916046,0.9829676,0.000016790682,0.000060573802,0.0000044370026],"study_design_scores_gemma":[0.00054611533,0.00036395423,0.095442414,0.00055014074,0.00007735076,2.778186e-8,0.000017436503,0.00005402135,0.901749,3.6119178e-7,0.0006548069,0.0005443489],"about_ca_topic_score_codex":0.000040297367,"about_ca_topic_score_gemma":0.000043449716,"teacher_disagreement_score":0.0812186,"about_ca_system_score_codex":0.000039407503,"about_ca_system_score_gemma":0.00026314383,"threshold_uncertainty_score":0.9997357},"labels":[],"label_agreement":null},{"id":"W2950871194","doi":"10.1101/565366","title":"The size of the immune repertoire of bacteria","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft; Aspen Center for Physics; Max-Planck-Gesellschaft; National Science Foundation","keywords":"Biology; Bacteria; Archaea; CRISPR; Immune system; Repertoire; Acquired immune system; Genome; Microbiology; Genetics; Computational biology; Gene; Physics","score_opus":0.004956973686977303,"score_gpt":0.22054999403538367,"score_spread":0.21559302034840636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950871194","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913628,0.0060547367,0.00043203856,0.000120761746,0.0014573078,0.0004333101,0.00010374262,0.000016859723,0.000018442493],"genre_scores_gemma":[0.9982867,0.0007692133,0.0005899958,0.000025075808,0.00019231485,0.00003342487,2.4126967e-7,0.00006096052,0.000042065225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985542,0.000078143195,0.00048389856,0.00041751837,0.00020042977,0.00026576107],"domain_scores_gemma":[0.99715316,0.00004776194,0.00039041037,0.0020788421,0.0002794453,0.00005035427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038112185,0.0002840814,0.0003314817,0.00002425044,0.00008118102,0.000030472962,0.0008291236,0.00035685577,0.000009200964],"category_scores_gemma":[0.0003640112,0.0001986148,0.0002662997,0.0001307131,0.0001633098,0.0000020671794,0.00083105586,0.0002733208,0.0000026198454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027382248,0.000025532949,0.0020688947,0.00019930107,0.00013177448,4.5115183e-7,0.000003760805,0.00030186042,0.99704874,0.000060071907,0.00012939058,0.0000028694549],"study_design_scores_gemma":[0.00018782644,0.000038375147,0.103996366,0.00014829088,0.000046170302,1.2418473e-8,0.0000027377619,0.000050079652,0.8867985,5.3725915e-7,0.008527468,0.00020361163],"about_ca_topic_score_codex":0.000023722103,"about_ca_topic_score_gemma":0.0000021968228,"teacher_disagreement_score":0.11025018,"about_ca_system_score_codex":0.00002196947,"about_ca_system_score_gemma":0.00030297058,"threshold_uncertainty_score":0.80992764},"labels":[],"label_agreement":null},{"id":"W2950980129","doi":"10.1007/s12250-019-00121-4","title":"Construction of a One-Vector Multiplex CRISPR/Cas9 Editing System to Inhibit Nucleopolyhedrovirus Replication in Silkworms","year":2019,"lang":"en","type":"article","venue":"Virologica Sinica","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Genome editing; Biology; Subgenomic mRNA; Multiplex; Gene; CRISPR interference; Guide RNA; Computational biology; Genome; Genetics","score_opus":0.010539336316233217,"score_gpt":0.28634715124713533,"score_spread":0.2758078149309021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950980129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99593437,0.00013746273,0.001887521,0.0001485488,0.00021377514,0.00042114902,0.000015808911,0.000034391935,0.001206988],"genre_scores_gemma":[0.99552137,0.000024565214,0.0040617576,0.00010893695,0.00016381421,0.000034169654,0.000025426149,0.000017721448,0.000042214277],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871814,0.000043637312,0.00040372607,0.0004907279,0.0001166875,0.00022707757],"domain_scores_gemma":[0.9991226,0.000029095008,0.00012826751,0.00059879076,0.000053148426,0.000068064415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027666087,0.00013885509,0.00023658524,0.000080949496,0.000026992475,0.000010885241,0.0001637838,0.00020107899,0.00002544427],"category_scores_gemma":[0.00022322749,0.00013352737,0.00006512269,0.00016585292,0.000042904965,0.000004360071,0.00011785123,0.000104816914,0.000036692756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000990799,0.000047186575,0.011234112,0.00005514163,0.000014849541,9.2390746e-7,0.000047465408,0.0010608297,0.9847291,0.00024179206,0.00006305924,0.0024064702],"study_design_scores_gemma":[0.0010304806,0.0010465479,0.10043918,0.00010898143,0.000019030145,0.000026868562,0.0004590944,0.0014990683,0.89028,0.000021978702,0.0047364915,0.00033223713],"about_ca_topic_score_codex":0.000044602682,"about_ca_topic_score_gemma":0.000025323334,"teacher_disagreement_score":0.09444906,"about_ca_system_score_codex":0.000024886129,"about_ca_system_score_gemma":0.000021388794,"threshold_uncertainty_score":0.5445088},"labels":[],"label_agreement":null},{"id":"W2951129593","doi":"10.1101/033068","title":"BAGEL: A computational framework for identifying essential genes from pooled library screens","year":2015,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Computational biology; Gene; Computer science; Biology; Genetics","score_opus":0.01627218944084809,"score_gpt":0.27942190508264086,"score_spread":0.2631497156417928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951129593","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46766686,0.006487014,0.5226287,0.00012450304,0.0012427088,0.00053789536,0.0011515176,0.00015692187,0.0000038272115],"genre_scores_gemma":[0.79432976,0.0001931899,0.20268196,0.00016760909,0.0022401458,0.00015996389,0.00004074445,0.00017932586,0.000007275381],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769706,0.0000658305,0.00045954826,0.001031772,0.00028547278,0.00046029998],"domain_scores_gemma":[0.99824643,0.000057313544,0.00023512258,0.00087954913,0.00029760943,0.00028400298],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022393827,0.0005055198,0.00043113748,0.00012912035,0.00012261642,0.000278589,0.0005625639,0.0007852419,0.000034467987],"category_scores_gemma":[0.00017839033,0.000602673,0.00025588527,0.00015048856,0.00007402601,0.000014239492,0.0007496952,0.00038268848,0.000016318645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012564253,0.000101370264,0.0021919734,0.00029042538,0.00067559484,0.000017695631,0.000011959358,0.01616608,0.97681284,0.00056704006,0.0030311786,0.000008187984],"study_design_scores_gemma":[0.001101635,0.00009764858,0.01444852,0.0004218966,0.0003701345,3.9262602e-8,0.000009835132,0.006438514,0.9634544,0.00029924596,0.011967596,0.0013905314],"about_ca_topic_score_codex":0.000016808543,"about_ca_topic_score_gemma":0.0000015923006,"teacher_disagreement_score":0.32666293,"about_ca_system_score_codex":0.000035096495,"about_ca_system_score_gemma":0.00053242786,"threshold_uncertainty_score":0.9996425},"labels":[],"label_agreement":null},{"id":"W2951560455","doi":"10.1101/160036","title":"Enhanced proofreading governs CRISPR-Cas9 targeting accuracy","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Charles A. King Trust; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Cas9; Nuclease; Proofreading; CRISPR; Genome editing; Computational biology; Förster resonance energy transfer; Guide RNA; Fidelity; Biology; Polymerase; Genetics; DNA; Computer science; Gene; Physics","score_opus":0.010778329444231372,"score_gpt":0.2738448240959287,"score_spread":0.26306649465169735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951560455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9186405,0.0058214366,0.07116771,0.000152027,0.0025753938,0.000981044,0.00026376653,0.0002548397,0.00014327426],"genre_scores_gemma":[0.99087334,0.0009683063,0.005701836,0.00010067012,0.0018741391,0.00021382574,0.000003677972,0.00021699077,0.00004722656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967602,0.000072557756,0.00057184347,0.0014000033,0.00036126524,0.00083412864],"domain_scores_gemma":[0.9965101,0.00003246585,0.00057040964,0.0021811966,0.00038842738,0.00031738624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005365513,0.0007567773,0.00057463784,0.00011455902,0.00034437288,0.0003729036,0.0011200395,0.00082694145,0.000031201504],"category_scores_gemma":[0.0012946518,0.00086065364,0.00029529826,0.00010244589,0.00010890549,0.000017380333,0.0012330624,0.0007254061,0.000048526592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002731333,0.00005468441,0.00081424223,0.0003349818,0.00017511573,0.000020578358,0.000009220867,0.00049468136,0.99666464,0.000044337725,0.0013467653,0.000013407001],"study_design_scores_gemma":[0.00042295989,0.000061435734,0.006909727,0.00028340015,0.000092809976,3.380156e-8,0.000003872362,0.00032080742,0.96833664,0.0000014307062,0.022547083,0.0010197763],"about_ca_topic_score_codex":0.000044788267,"about_ca_topic_score_gemma":0.0000051825823,"teacher_disagreement_score":0.07223281,"about_ca_system_score_codex":0.000116405994,"about_ca_system_score_gemma":0.00044418895,"threshold_uncertainty_score":0.9993844},"labels":[],"label_agreement":null},{"id":"W2951624220","doi":"10.1101/336016","title":"The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"National Institutes of Health","keywords":"PCSK9; Biology; Secretion; Endoplasmic reticulum; Cell biology; Proprotein convertase; Biotinylation; Kexin; HEK 293 cells; Secretory pathway; Calnexin; LDL receptor; Receptor; Golgi apparatus; Molecular biology; Biochemistry; Calreticulin","score_opus":0.006638573943902119,"score_gpt":0.2255518486882647,"score_spread":0.21891327474436256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951624220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9847339,0.005192026,0.007626717,0.00016274853,0.0014462022,0.00066735275,0.000110630135,0.00004772712,0.000012687312],"genre_scores_gemma":[0.99780136,0.00033945302,0.0007913811,0.000027887698,0.0008370906,0.00010377026,0.000001967514,0.000081511556,0.000015561256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99810743,0.00013693783,0.00042596008,0.0006160864,0.00030045735,0.00041310443],"domain_scores_gemma":[0.99758637,0.000039860854,0.00028535962,0.0015169126,0.00046605818,0.000105410625],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008625483,0.00037615068,0.00026850207,0.000048416045,0.0002341813,0.000092022136,0.0007075145,0.0004135128,0.000012714356],"category_scores_gemma":[0.00024897305,0.0002666091,0.00019675867,0.0001791897,0.00023964347,0.0000018591688,0.0005601989,0.00033692655,0.000015757318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026037793,0.000040049064,0.0004312153,0.00012253434,0.000116562194,0.0000010089057,0.000012289917,0.0006769395,0.99798554,0.00005065335,0.00053302804,0.00000413196],"study_design_scores_gemma":[0.00016104862,0.00009704915,0.0039800038,0.000101078425,0.00006068193,1.2742285e-8,0.00000679274,0.000884362,0.9714314,7.4364186e-7,0.022954868,0.00032200056],"about_ca_topic_score_codex":0.00002312724,"about_ca_topic_score_gemma":0.0000029159264,"teacher_disagreement_score":0.026554191,"about_ca_system_score_codex":0.000042536103,"about_ca_system_score_gemma":0.0002605026,"threshold_uncertainty_score":0.9999786},"labels":[],"label_agreement":null},{"id":"W2951624526","doi":"10.1016/j.ydbio.2019.06.004","title":"Parental allele-specific protein expression in single cells In vivo","year":2019,"lang":"en","type":"article","venue":"Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Allele; Locus (genetics); Genetics; Gene; Protein expression; Molecular biology; Ribosomal protein; Ribosome; RNA","score_opus":0.0077488229292203645,"score_gpt":0.253905808321041,"score_spread":0.24615698539182063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951624526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971878,0.0003504543,0.00022595935,0.000014429812,0.00016434194,0.00029869034,0.000010094093,0.0000081897315,0.001740064],"genre_scores_gemma":[0.9962225,0.000053462245,0.0031053962,0.00004341948,0.000034348075,0.000038647846,0.000111229325,0.00001454543,0.00037646122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907935,0.000032572523,0.00021731583,0.00034836057,0.000044818364,0.00027760278],"domain_scores_gemma":[0.9998,0.000005191893,0.00002741536,0.000121254685,0.00000809864,0.000038013994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000847318,0.00013946604,0.00013759876,0.00007933128,0.0000130188755,0.0000063955076,0.00013275564,0.0001612292,0.00016795378],"category_scores_gemma":[0.000005558311,0.00013712043,0.000028457363,0.00008366326,0.000026376101,0.0000026422665,0.00013325988,0.00008228939,0.000054828088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046131136,0.000065103566,0.034250274,0.000008474356,0.0000033575332,0.0000038084545,0.000078196084,0.000050633083,0.9643629,0.000008675628,0.0002344705,0.00088793965],"study_design_scores_gemma":[0.0006403289,0.00010974374,0.0074023944,0.00002240542,2.758019e-7,0.000006476763,0.00016922136,0.000008746823,0.94253254,0.000013911478,0.04890905,0.00018493284],"about_ca_topic_score_codex":0.000011845683,"about_ca_topic_score_gemma":0.00008514001,"teacher_disagreement_score":0.04867458,"about_ca_system_score_codex":0.000046442226,"about_ca_system_score_gemma":0.000026373045,"threshold_uncertainty_score":0.5591609},"labels":[],"label_agreement":null},{"id":"W2951735047","doi":"10.1089/crispr.2018.0053","title":"The Human Right to Science and the Regulation of Human Germline Engineering","year":2019,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"Universidad Autónoma de Madrid; Banco Santander","keywords":"Germline; Corporate governance; Legislation; Political science; Human rights; Obstacle; Ideal (ethics); Engineering ethics; Autonomy; CRISPR; Law and economics; Engineering; Law; Sociology; Biology; Management; Genetics; Economics","score_opus":0.018031878872574895,"score_gpt":0.35915836510583005,"score_spread":0.34112648623325514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951735047","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022236388,0.9953681,0.0012758719,0.00017019233,0.0003236719,0.00042284312,0.0000037287791,0.000003936632,0.00020800166],"genre_scores_gemma":[0.024959711,0.9734097,0.00007682026,0.000031381896,0.0008328966,0.000017109387,0.0000058364317,0.00003757034,0.0006289506],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99878806,0.00007881328,0.000422379,0.00018442735,0.00028465,0.00024169026],"domain_scores_gemma":[0.99895173,0.00006657744,0.00021786382,0.0005344706,0.00016055442,0.00006881389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022117414,0.00019723787,0.0003720823,0.00007206499,0.00061882596,0.00012736699,0.0007541588,0.00008372812,0.000007494826],"category_scores_gemma":[0.00016805003,0.00008575007,0.00017625223,0.0001811264,0.00028278783,0.0000035341523,0.0002415826,0.00032708741,0.0000021537078],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007262004,0.000058644135,0.00001189817,0.004758821,0.0009764694,0.0000050531444,0.0010176713,0.0031137741,0.30875695,0.011939877,0.010405887,0.6588823],"study_design_scores_gemma":[0.00029382663,0.0000863208,0.000081257574,0.0008329839,0.00028332858,0.00024288197,0.000027110184,0.0000873797,0.0057286574,0.000088745175,0.99205476,0.00019273796],"about_ca_topic_score_codex":0.0000031555044,"about_ca_topic_score_gemma":0.0000030215638,"teacher_disagreement_score":0.98164886,"about_ca_system_score_codex":0.000024662913,"about_ca_system_score_gemma":0.000103608494,"threshold_uncertainty_score":0.47595713},"labels":[],"label_agreement":null},{"id":"W2951985652","doi":"10.3389/fmicb.2018.02527","title":"Evolution of Bacterial Gene Transfer Agents","year":2018,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gene; Recombination; Prophage; Biology; Epistasis; Genetics; DNA; Bacteriophage; Escherichia coli","score_opus":0.0042030547473137945,"score_gpt":0.23859565119018275,"score_spread":0.23439259644286894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951985652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8617437,0.00069353863,0.13597882,0.000009512586,0.001327961,0.000080772275,0.00003305079,0.0000038323114,0.00012882377],"genre_scores_gemma":[0.9935472,0.00006501983,0.0058348035,0.000027097978,0.00028235654,0.000004405468,0.00012687744,0.000010682231,0.00010154313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940276,0.00003402264,0.00016815648,0.00019745632,0.00001555156,0.00018202931],"domain_scores_gemma":[0.9997673,0.0000015110705,0.000016493852,0.00016024851,0.00003232912,0.000022109594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008284925,0.0000877268,0.00013285717,0.00006634982,0.000015574702,0.0000018091796,0.00012045991,0.00016136229,0.00004142488],"category_scores_gemma":[0.000012842217,0.00009115574,0.000046022382,0.00006255767,0.00013324319,0.0000011552639,0.00003222059,0.00004006927,0.0000037892942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009832092,0.00002093201,0.006328784,0.000006649295,0.000022574915,5.0183564e-7,0.00005515848,0.000045707056,0.9868276,0.00000766986,0.00606289,0.00052318716],"study_design_scores_gemma":[0.000601634,0.00024163938,0.0043880977,0.000005603482,0.000007863834,0.000012787541,0.000039199305,0.000055329536,0.9647392,0.000027432272,0.029771343,0.00010987847],"about_ca_topic_score_codex":0.000010364346,"about_ca_topic_score_gemma":0.00003036654,"teacher_disagreement_score":0.13180353,"about_ca_system_score_codex":0.00001911665,"about_ca_system_score_gemma":0.000028031058,"threshold_uncertainty_score":0.37172234},"labels":[],"label_agreement":null},{"id":"W2952025615","doi":"10.1101/354258","title":"A <i>Drosophila</i> CRISPR/Cas9 toolkit for conditionally manipulating gene expression in the prothoracic gland as a test case for polytene tissues","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Cas9; Biology; Polytene chromosome; Prothoracic gland; RNA interference; Gene; Gene expression; Regulation of gene expression; Phenotype; Computational biology; Genome editing; Drosophila melanogaster; Cell biology; Genetics; RNA","score_opus":0.016254430559900068,"score_gpt":0.29431860269340426,"score_spread":0.2780641721335042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952025615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95716333,0.002440533,0.03535075,0.00024224476,0.00043913003,0.003336036,0.0009543019,0.000066201144,0.0000074549785],"genre_scores_gemma":[0.9660196,0.00010316721,0.029286709,0.00027029202,0.0016610491,0.0024960435,0.000019813098,0.00013281562,0.000010530555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977075,0.00006674793,0.0005176751,0.00095997157,0.0002171652,0.0005309817],"domain_scores_gemma":[0.9981755,0.00012550171,0.0002572957,0.0009330335,0.000381373,0.00012730142],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006894417,0.00050067424,0.00038176577,0.00011589871,0.00023750235,0.00018402541,0.00046587395,0.0005209013,0.000008114962],"category_scores_gemma":[0.00060200965,0.000457396,0.00018991099,0.00014094883,0.000081112186,0.000010973943,0.00028073855,0.0002615679,0.0000047461167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001011592,0.00011931905,0.0013720097,0.0004947258,0.000052332707,0.000100121906,0.000020196994,0.0003074675,0.99669516,0.000032426105,0.0007016168,0.000003457547],"study_design_scores_gemma":[0.0009583845,0.00038367012,0.003413222,0.00028960555,0.00009351489,0.0000040121054,0.000013100682,0.0009960571,0.98662317,0.000016497757,0.0065352595,0.0006735273],"about_ca_topic_score_codex":0.00002300085,"about_ca_topic_score_gemma":0.000012767836,"teacher_disagreement_score":0.010072018,"about_ca_system_score_codex":0.00004916342,"about_ca_system_score_gemma":0.00024223053,"threshold_uncertainty_score":0.99978775},"labels":[],"label_agreement":null},{"id":"W2952221338","doi":"10.1101/173252","title":"BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Genome instability; Bloom syndrome; Biology; Genetics; Gene; Sister chromatid exchange; Sister chromatids; Genome; Helicase; DNA; DNA damage; Chromosome; RNA","score_opus":0.013229754748321545,"score_gpt":0.26519555340103135,"score_spread":0.2519657986527098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952221338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98922056,0.0060608517,0.0026023218,0.00019115859,0.0010234741,0.0005739797,0.00022290729,0.000085550346,0.000019184832],"genre_scores_gemma":[0.9954612,0.002207034,0.0014842611,0.000053555323,0.00041902534,0.00019766386,0.0000074827,0.00012844488,0.000041296273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976058,0.00008667756,0.0004691129,0.0010717874,0.00023387354,0.0005327359],"domain_scores_gemma":[0.9977044,0.000017477563,0.00022603462,0.0016328965,0.00022091712,0.00019826154],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037656014,0.0005339427,0.00045203412,0.00018806815,0.00015624054,0.00014685474,0.00066708314,0.0007149314,0.000036786012],"category_scores_gemma":[0.00019154474,0.00062619697,0.00019392373,0.00010537791,0.000092061906,0.000010382399,0.0005212197,0.00036986818,0.000022270986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046443132,0.00010536204,0.003728471,0.00029913968,0.00007630664,0.000038656413,0.000009477784,0.0011092309,0.9942259,0.000019942556,0.00032689137,0.000014180332],"study_design_scores_gemma":[0.0007482825,0.00006488446,0.042074636,0.00016999227,0.00005442741,7.705662e-8,0.000001966975,0.00058671704,0.94277483,0.0000017613221,0.012820109,0.0007023092],"about_ca_topic_score_codex":0.000078213634,"about_ca_topic_score_gemma":0.00006118485,"teacher_disagreement_score":0.05145106,"about_ca_system_score_codex":0.00011795625,"about_ca_system_score_gemma":0.00021378488,"threshold_uncertainty_score":0.99961895},"labels":[],"label_agreement":null},{"id":"W2952358323","doi":"10.1093/gbe/evy201","title":"The Grayling Genome Reveals Selection on Gene Expression Regulation after Whole-Genome Duplication","year":2018,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Norges Forskningsråd; Universitetet i Oslo; National Science Council; Norwegian Sequencing Centre; McGill University","keywords":"Biology; Gene duplication; Genome; Grayling; Gene; Genetics; Selection (genetic algorithm); Computational biology; Gene expression; Regulation of gene expression; Evolutionary biology; Fish <Actinopterygii>; Fishery","score_opus":0.005507323533176581,"score_gpt":0.2596455190179773,"score_spread":0.2541381954848007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952358323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9172953,0.0030692334,0.07884689,0.00015124779,0.00020562962,0.00023931338,0.000021673548,0.000026775186,0.00014394044],"genre_scores_gemma":[0.99699503,0.0003167196,0.0007087408,0.00007510629,0.0010963423,0.00006847591,0.0003385855,0.000017606704,0.00038341092],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998954,0.00007806607,0.0002165002,0.00041068712,0.00006224287,0.0002785143],"domain_scores_gemma":[0.99945855,0.000013454001,0.00008415755,0.00027767837,0.00010556246,0.0000606018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002748615,0.00015795315,0.000101917845,0.000051704115,0.0004371699,0.000023064036,0.00009959599,0.00024051183,0.000009769501],"category_scores_gemma":[0.000038728325,0.0001270539,0.00004547653,0.00010514787,0.00013885999,0.000006789563,0.00006542948,0.00008843104,0.000034927652],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017345403,0.000011485255,0.003591701,0.000005809906,0.000017065464,8.602424e-8,0.000044576005,0.00026044133,0.9951304,0.0001602683,0.000026336666,0.00057832844],"study_design_scores_gemma":[0.00039823583,0.0007778261,0.83665526,0.00001149014,0.0000259067,0.000025713623,0.00004264211,0.00036613105,0.11993343,0.0016963482,0.039751478,0.0003155276],"about_ca_topic_score_codex":0.000006443438,"about_ca_topic_score_gemma":0.000016500808,"teacher_disagreement_score":0.875197,"about_ca_system_score_codex":0.00004735214,"about_ca_system_score_gemma":0.000020297693,"threshold_uncertainty_score":0.51811075},"labels":[],"label_agreement":null},{"id":"W2952798674","doi":"10.1101/618116","title":"An antisense oligonucleotide leads to suppressed transcriptional elongation of <i>Hdac2</i> and long-term memory enhancement","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Abbott (Canada)","funders":"","keywords":"Gene knockdown; Gene silencing; Histone deacetylase 2; RNA; Biology; Messenger RNA; Gene isoform; Psychological repression; Gene; Gene expression; Molecular biology; Cell biology; Genetics; Histone; Histone deacetylase","score_opus":0.007648963148647503,"score_gpt":0.25048514746610034,"score_spread":0.24283618431745285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952798674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9677614,0.0017059798,0.029032558,0.000049223912,0.0005983648,0.0006253664,0.00018606192,0.000036644415,0.0000043884515],"genre_scores_gemma":[0.99562633,0.0005035495,0.0033020163,0.00012039799,0.0002889912,0.00006052201,0.000007661683,0.0000811166,0.000009418085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981518,0.00006239592,0.00040729635,0.0008041571,0.00024654542,0.00032784772],"domain_scores_gemma":[0.9984655,0.000009547468,0.00014883313,0.0009104604,0.0002499742,0.00021571599],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026792937,0.00038101434,0.00036932988,0.00013188261,0.00004984555,0.000060641643,0.0002913164,0.0003511932,0.000017361603],"category_scores_gemma":[0.00003232191,0.0004484362,0.00010215529,0.000104710394,0.000066761284,0.000010354691,0.00017818542,0.00021005445,0.0000072954713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000705541,0.000101957616,0.00991225,0.00039592653,0.00008108959,0.0000052505916,0.000014631299,0.001893141,0.98741263,0.000018534167,0.00008753203,0.000006514436],"study_design_scores_gemma":[0.00039350468,0.00017760119,0.18943809,0.00012418328,0.00006002967,4.153878e-8,0.0000015584918,0.00015421207,0.8090781,1.4913758e-7,0.00017863399,0.00039388202],"about_ca_topic_score_codex":0.0000106609305,"about_ca_topic_score_gemma":0.0000049352734,"teacher_disagreement_score":0.17952584,"about_ca_system_score_codex":0.000031817177,"about_ca_system_score_gemma":0.00016525062,"threshold_uncertainty_score":0.99979675},"labels":[],"label_agreement":null},{"id":"W2952862039","doi":"10.1261/rna.062083.117","title":"Priming in a permissive type I-C CRISPR–Cas system reveals distinct dynamics of spacer acquisition and loss","year":2017,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"Canadian Institutes of Health Research; Connaught Fund; University of Toronto; Canada Foundation for Innovation","keywords":"Biology; CRISPR; CRISPR interference; Computational biology; Genetics; Context (archaeology); Adaptation (eye); Cas9; Gene","score_opus":0.008299028463079528,"score_gpt":0.30578559410814704,"score_spread":0.29748656564506754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952862039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99481905,0.00052857574,0.003472539,0.00006012104,0.00008826929,0.00008077665,0.000011105712,0.0000038622356,0.00093572383],"genre_scores_gemma":[0.9993624,0.00006420294,0.0003009638,0.0000057730504,0.0000664802,0.0000026647083,0.000018431689,0.000009911501,0.00016915053],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995936,0.000010733116,0.00010676786,0.00014049983,0.000046691028,0.00010170703],"domain_scores_gemma":[0.99960715,0.00000486571,0.00006850482,0.00024681038,0.00003870284,0.00003398459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008621018,0.00007137988,0.000104849634,0.00002009532,0.00004714304,0.00001710671,0.000072318406,0.000068985675,0.0000024144992],"category_scores_gemma":[0.00005768224,0.000070463895,0.000022025957,0.000015444959,0.00003423836,0.0000025357679,0.00007577213,0.00003611936,8.063511e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014559548,0.000040808212,0.12778673,0.0008265334,0.000055802837,0.000049172697,0.00038375138,0.00030439737,0.8623502,0.0007101797,0.00012455117,0.007222265],"study_design_scores_gemma":[0.0008929175,0.00025195422,0.70184535,0.0004740488,0.000052766023,0.000092799695,0.00055045297,0.0064022304,0.2885478,0.000090907444,0.00041961897,0.00037914052],"about_ca_topic_score_codex":0.0000463289,"about_ca_topic_score_gemma":0.000067451256,"teacher_disagreement_score":0.57405865,"about_ca_system_score_codex":0.000017853154,"about_ca_system_score_gemma":0.000013257601,"threshold_uncertainty_score":0.2873434},"labels":[],"label_agreement":null},{"id":"W2953135660","doi":"10.1101/342485","title":"Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; University of Oxford; International Seafood Sustainability Foundation; Wellcome Trust","keywords":"Transfer RNA; RNA polymerase III; Computational biology; CRISPR; Cas9; RNA; Guide RNA; Biology; Computer science; Genetics; Gene; RNA-dependent RNA polymerase","score_opus":0.009617276033501782,"score_gpt":0.25077170365802437,"score_spread":0.24115442762452258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953135660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9748828,0.009092241,0.014711826,0.000049649614,0.0006096147,0.00043984776,0.000061628445,0.000120354525,0.000032048247],"genre_scores_gemma":[0.9833048,0.0012906946,0.013494672,0.000051312258,0.0015538242,0.00009666212,0.0000015751438,0.00016022292,0.000046255085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975364,0.000042518146,0.0004518519,0.0011379427,0.00024983543,0.0005814567],"domain_scores_gemma":[0.99836165,0.00001211214,0.0002514422,0.0009180168,0.00022905011,0.0002277469],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036979275,0.00059767935,0.00042327808,0.00015948951,0.00033250998,0.0002502815,0.0003738676,0.0006206207,0.00001983406],"category_scores_gemma":[0.0000760206,0.0006156365,0.0001137342,0.00012400372,0.00016232897,0.000018499602,0.0009815186,0.00038253696,0.0000038967037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003211561,0.00004923801,0.00056509086,0.00038411297,0.0000520019,0.0000120904415,0.000027276554,0.00010781315,0.9979482,0.0000040089085,0.00078143226,0.000036597536],"study_design_scores_gemma":[0.00034150484,0.00010302956,0.0030600708,0.00058727735,0.00004402885,1.6582665e-7,0.0000117015115,0.00038050936,0.9721417,0.0000013073599,0.02259625,0.0007324506],"about_ca_topic_score_codex":0.000013332555,"about_ca_topic_score_gemma":0.0000027704475,"teacher_disagreement_score":0.025806518,"about_ca_system_score_codex":0.0000665569,"about_ca_system_score_gemma":0.00026906017,"threshold_uncertainty_score":0.9996295},"labels":[],"label_agreement":null},{"id":"W2953212411","doi":"10.1101/117341","title":"Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Canadian Institute for Advanced Research; Amgen (Canada); Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Cancer Society Research Institute; Cancer Prevention and Research Institute of Texas; University of Texas MD Anderson Cancer Center; Canada Research Chairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"CRISPR; Gene knockout; Computational biology; Biology; Gene; Functional genomics; Cas9; Genome editing; Genome; Guide RNA; Genetics; Human genome; Genomics","score_opus":0.02269493981156739,"score_gpt":0.28364804565985485,"score_spread":0.26095310584828746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953212411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81361055,0.0142117515,0.17006643,0.00007778678,0.00056081935,0.001210295,0.00018069547,0.000054085544,0.000027569553],"genre_scores_gemma":[0.98945343,0.0013937415,0.008548948,0.000038978098,0.0003495659,0.00011566078,0.0000019800614,0.0000897372,0.000007930661],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794656,0.00014506413,0.0003879502,0.0007896981,0.00038105447,0.00034966497],"domain_scores_gemma":[0.997308,0.000025574365,0.0003471563,0.001436325,0.0007099436,0.0001730064],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001309486,0.00041193358,0.00040786818,0.00012922262,0.00012538841,0.00009680454,0.00044361618,0.00052502943,0.000014932638],"category_scores_gemma":[0.0007082638,0.0004658973,0.00011155022,0.00006253169,0.0001310142,0.00000684688,0.0005409148,0.0002699463,0.0000052826254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002986345,0.00003835308,0.002476237,0.00019464864,0.00021378606,0.0000045124643,0.0000063284388,0.00446509,0.99234724,0.000010606991,0.00019410228,0.000019251633],"study_design_scores_gemma":[0.0006319611,0.00013867259,0.12808686,0.00016457876,0.0003452809,4.0270876e-8,0.0000027860672,0.0030874172,0.8642623,0.0000037588318,0.0026307437,0.00064563676],"about_ca_topic_score_codex":0.000029341565,"about_ca_topic_score_gemma":0.0000030033775,"teacher_disagreement_score":0.17584288,"about_ca_system_score_codex":0.000049992712,"about_ca_system_score_gemma":0.0004812367,"threshold_uncertainty_score":0.9997793},"labels":[],"label_agreement":null},{"id":"W2953230159","doi":"10.1101/053058","title":"Continuous Genetic Recording with Self-Targeting CRISPR-Cas in Human Cells","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Office of Naval Research; Natural Sciences and Engineering Research Council of Canada; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; National Institutes of Health; National Science Foundation","keywords":"Biology; CRISPR; Cas9; Computational biology; DNA; Cell biology; Population; Genetics; Gene; Medicine","score_opus":0.005271597011996058,"score_gpt":0.23114689708914482,"score_spread":0.22587530007714876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953230159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97687346,0.0021633583,0.019254792,0.000057887966,0.0007005161,0.0006887666,0.00005842344,0.00017314556,0.000029650811],"genre_scores_gemma":[0.98693657,0.0004013039,0.011323427,0.000067910936,0.0008663475,0.00016870347,8.298618e-7,0.00021920144,0.000015713804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99689204,0.00010710325,0.00062226556,0.001295193,0.00026412096,0.00081929716],"domain_scores_gemma":[0.9980239,0.000023021077,0.00030316913,0.0011514452,0.0002565291,0.00024190742],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042364292,0.0006871677,0.0005839211,0.00022615118,0.00012594523,0.00012752185,0.00055811467,0.0006405598,0.000021880927],"category_scores_gemma":[0.00006508599,0.00065635587,0.00015262679,0.00020799533,0.00007443316,0.000008036199,0.00052241306,0.0005177987,0.000017304774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028261984,0.00007566666,0.016873548,0.00024024691,0.00012938306,0.00007459425,0.000010484238,0.00044297546,0.9817093,0.00001663986,0.00039476133,0.000004127707],"study_design_scores_gemma":[0.00087457604,0.00016964925,0.019039067,0.00043453334,0.0000787804,8.2220645e-8,0.000005320702,0.000106860796,0.97382236,0.0000018383157,0.004438029,0.0010289141],"about_ca_topic_score_codex":0.000052714688,"about_ca_topic_score_gemma":0.000010568336,"teacher_disagreement_score":0.010063103,"about_ca_system_score_codex":0.00013786221,"about_ca_system_score_gemma":0.00024835032,"threshold_uncertainty_score":0.9995888},"labels":[],"label_agreement":null},{"id":"W2954106725","doi":"10.1073/pnas.1900751116","title":"Meiotic viral attenuation through an ancestral apoptotic pathway","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Endonuclease; Biology; Apoptosis; Cell biology; Programmed cell death; Meiosis; Budding; Yeast; Budding yeast; Genetics; Saccharomyces cerevisiae; DNA; Gene","score_opus":0.026122185541236066,"score_gpt":0.3306081097050196,"score_spread":0.3044859241637835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954106725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968094,0.00010176227,0.000018674755,0.00027896411,0.000030274843,0.0001039526,0.000004967214,0.0000035246617,0.002648477],"genre_scores_gemma":[0.99799126,0.000019747216,0.0016659733,0.00010407973,0.00009197301,0.000002559932,6.2004506e-7,0.0000033227727,0.00012044499],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917805,0.0000030751257,0.00015254156,0.00018149619,0.0003806573,0.000104161234],"domain_scores_gemma":[0.9997499,0.000007995959,0.00011960929,0.000009304451,0.00009627612,0.000016934666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003432381,0.00006315011,0.00007268283,0.000028494658,0.00004934902,0.000010761385,0.00035335793,0.00006221125,0.000006364766],"category_scores_gemma":[0.0000765687,0.00004587231,0.00004449764,0.00015497947,0.00016796839,0.00003507008,0.00005617607,0.000056361943,0.0000013198903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006082051,0.000015532529,0.0048149903,0.00002553638,0.000005373443,6.0212463e-10,0.000053061438,0.0014177524,0.987452,0.0060116304,0.00004889542,0.00014916998],"study_design_scores_gemma":[0.000121712095,0.00011929583,0.046089325,0.000021360269,0.000004145989,0.0000034074615,0.00008676232,0.0009578476,0.94813734,0.004140411,0.00025234025,0.000066034685],"about_ca_topic_score_codex":0.00000226205,"about_ca_topic_score_gemma":5.5421488e-8,"teacher_disagreement_score":0.04127433,"about_ca_system_score_codex":0.000006427486,"about_ca_system_score_gemma":0.000020034226,"threshold_uncertainty_score":0.18706186},"labels":[],"label_agreement":null},{"id":"W2954109914","doi":"10.3390/diseases7030047","title":"Cell and Gene Therapies for Mucopolysaccharidoses: Base Editing and Therapeutic Delivery to the CNS","year":2019,"lang":"en","type":"review","venue":"Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Rare Disease Foundation; BC Children's Hospital; Children's Hospital Foundation","keywords":"Genome editing; CRISPR; Computational biology; Genetic enhancement; Genome; Gene; Biology; Disease; RNA editing; Neurodegeneration; Neuroscience; Bioinformatics; Medicine; Genetics; RNA; Pathology","score_opus":0.02153632507444079,"score_gpt":0.31924919554857234,"score_spread":0.29771287047413153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954109914","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001573133,0.99591863,0.0010986265,0.0000338996,0.00018456783,0.00074687024,0.00042339705,0.000009393476,0.000011505026],"genre_scores_gemma":[0.0054389993,0.9930125,0.00016634396,0.00022464746,0.0006016491,0.00019086676,0.00016462925,0.000047874233,0.00015253043],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992142,0.000031436128,0.00015390977,0.00034893744,0.00005986206,0.00019166188],"domain_scores_gemma":[0.9994666,0.00007043238,0.000054858643,0.00028817783,0.000029018505,0.00009091675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006393291,0.00024437168,0.00033825892,0.000035762765,0.00008591409,0.000051929383,0.0001431156,0.00009675919,0.00000583272],"category_scores_gemma":[0.000027291386,0.00016494999,0.00016150324,0.000040337174,0.000031157644,0.0000013817887,0.00011012796,0.000051051247,0.0000028700777],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016028467,0.000030011406,0.000036304897,0.0057149427,0.00021987407,0.0000015670691,0.000084113024,0.000019150712,0.0014842808,0.000008552845,0.0016971778,0.99068797],"study_design_scores_gemma":[0.00016335155,0.00011304697,0.000027410208,0.00035331806,0.0006729531,0.000008424533,0.000105809624,0.000028390834,0.00068260514,0.0000061024825,0.99757123,0.00026738015],"about_ca_topic_score_codex":0.0000042107617,"about_ca_topic_score_gemma":0.0000023633986,"teacher_disagreement_score":0.99587405,"about_ca_system_score_codex":0.0000049155,"about_ca_system_score_gemma":0.00006043136,"threshold_uncertainty_score":0.6726465},"labels":[],"label_agreement":null},{"id":"W2954180890","doi":"10.1039/c9sc01432b","title":"Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers","year":2019,"lang":"en","type":"article","venue":"Chemical Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bentley (Canada)","funders":"National Health and Medical Research Council; Medical Research Council; Cancer Council Western Australia; National Institutes of Health; Australian Research Council; National Breast Cancer Foundation","keywords":"Pharmacology; Medicine","score_opus":0.0039552727136354885,"score_gpt":0.26953942248311924,"score_spread":0.26558414976948375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954180890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99543875,0.0003924113,0.0032542835,0.000032026914,0.00025692792,0.00009239521,0.000006576358,0.000011293218,0.0005153257],"genre_scores_gemma":[0.99851096,0.000010761028,0.0011396778,0.00009519098,0.000085250744,0.0000024203518,0.000019227062,0.000012364746,0.0001241428],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998881,0.000006108516,0.00012427471,0.00039339438,0.00019953714,0.00039567892],"domain_scores_gemma":[0.99954844,0.00000584089,0.000026009378,0.00022515267,0.00003690687,0.00015767851],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010488168,0.00011963703,0.00010059478,0.000027642469,0.000064261265,0.000033818174,0.00033063823,0.00008434735,0.0000595802],"category_scores_gemma":[0.00005685264,0.00011202777,0.00004231215,0.00015463498,0.0001704732,0.000007872186,0.00016255239,0.00009280097,0.000015751313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008074389,0.00001888224,0.00029636294,0.000009633231,0.0000024058731,9.611301e-7,0.000023072453,0.000092982846,0.9987645,0.000003048388,0.00032415733,0.00045591465],"study_design_scores_gemma":[0.0001962697,0.000049247865,0.00029514587,0.00001401565,0.0000049793357,0.000017087063,0.00003752169,0.0028552865,0.99571496,0.000007912864,0.0006371754,0.00017040402],"about_ca_topic_score_codex":0.000022308162,"about_ca_topic_score_gemma":2.441149e-7,"teacher_disagreement_score":0.0030722045,"about_ca_system_score_codex":0.000027047447,"about_ca_system_score_gemma":0.000076550314,"threshold_uncertainty_score":0.45683596},"labels":[],"label_agreement":null},{"id":"W2954359362","doi":"10.17912/micropub.biology.000146","title":"Tools for Mos1-mediated single copy insertion (mosSCI) with excisable unc-119(+) or NeoR (G418) selection cassettes","year":2019,"lang":"en","type":"article","venue":"PubMed","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institutes of Health","keywords":"Selection (genetic algorithm); Computer science; Genetics; Computational biology; Biology; Artificial intelligence","score_opus":0.01781783919308359,"score_gpt":0.24846864169029084,"score_spread":0.23065080249720726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954359362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846682,0.000159573,0.013096082,0.00013807442,0.00023620915,0.0011551082,0.00002386869,0.00004725125,0.0004756532],"genre_scores_gemma":[0.9943734,0.000021680573,0.0013275415,0.00017368082,0.00021260619,0.00088463665,0.00025865762,0.000036933492,0.0027108814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902964,0.000015319369,0.00015504385,0.00031861456,0.000105532345,0.00037583284],"domain_scores_gemma":[0.999523,0.00004259992,0.00005334524,0.00019443815,0.000099450124,0.00008719952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014089649,0.00015279959,0.00013982026,0.000038514678,0.000052238003,0.00006836467,0.00009374136,0.00012970457,0.00002078385],"category_scores_gemma":[0.00015915351,0.00012533412,0.000046555855,0.00015248847,0.00002061695,0.000013857861,0.00002563104,0.00005701316,0.000008855145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014068878,0.00017751964,0.012973571,0.00015267346,0.00015504178,0.000002225236,0.00004829065,0.004089745,0.93516976,0.000024015253,0.0052768434,0.040523436],"study_design_scores_gemma":[0.0021425423,0.00080689095,0.042107176,0.0000150525,0.000047073743,0.00003399624,0.00008673445,0.0010851517,0.8572638,0.000020705116,0.09595881,0.00043208525],"about_ca_topic_score_codex":0.000016360957,"about_ca_topic_score_gemma":0.000108270644,"teacher_disagreement_score":0.09068196,"about_ca_system_score_codex":0.00003500947,"about_ca_system_score_gemma":0.000041721196,"threshold_uncertainty_score":0.5110977},"labels":[],"label_agreement":null},{"id":"W2956128574","doi":"10.1016/j.plasmid.2019.102419","title":"Assembly of large mobilizable genetic cargo by double recombinase operated insertion of DNA (DROID)","year":2019,"lang":"en","type":"article","venue":"Plasmid","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Plasmid; Biology; Recombinase; CRISPR; DNA; Cas9; Trans-activating crRNA; Genetics; Cre recombinase; Computational biology; Insert (composites); Gene; Transgene; Recombination","score_opus":0.004766488571567525,"score_gpt":0.26018294119045965,"score_spread":0.2554164526188921,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2956128574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99693036,0.0010349752,0.00082296826,0.00001176684,0.00017029815,0.00020201044,0.000045777506,0.000008905068,0.00077296305],"genre_scores_gemma":[0.9984315,0.00017600674,0.00035369888,0.000024374911,0.000016237833,0.000011875838,0.00015578534,0.00002102322,0.0008094771],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992329,0.000017806144,0.0002356685,0.00022240955,0.000099536366,0.00019166923],"domain_scores_gemma":[0.9995041,0.000007089177,0.00006392837,0.00029403958,0.00008137345,0.00004949024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099842015,0.00011587691,0.00017321983,0.000034907072,0.000016205902,0.0000056578738,0.00012627152,0.00011874612,0.00006411178],"category_scores_gemma":[0.00001422475,0.000118960765,0.000059462152,0.00009741734,0.000015476195,0.0000032972582,0.000059009686,0.000049111735,0.000014860126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086683125,0.00011120673,0.0043303994,0.00007980586,0.000032295124,3.883765e-7,0.00002714268,0.0019926445,0.991666,0.000014270595,0.0015661746,0.00009299054],"study_design_scores_gemma":[0.001339217,0.00032611625,0.0015872911,0.00001939729,0.000013672398,0.0000034607622,0.000041284908,0.0015998792,0.9890361,0.0000041354856,0.0058984417,0.00013102514],"about_ca_topic_score_codex":0.00006333805,"about_ca_topic_score_gemma":0.000021644184,"teacher_disagreement_score":0.0043322667,"about_ca_system_score_codex":0.00000781082,"about_ca_system_score_gemma":0.000039573828,"threshold_uncertainty_score":0.4851079},"labels":[],"label_agreement":null},{"id":"W2956334572","doi":"10.3390/genes10070523","title":"Synthetic DNA and RNA Programming","year":2019,"lang":"en","type":"editorial","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Synthetic biology; Computational biology; RNA; Biology; DNA; Molecular cell biology; Genetics; Gene; Cell biology","score_opus":0.0038601628537974315,"score_gpt":0.2684895410953251,"score_spread":0.26462937824152766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2956334572","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017838484,0.038804114,0.0016877545,0.000029979794,0.940469,0.00038526405,0.000079979975,0.000039945404,0.0006654556],"genre_scores_gemma":[0.015735695,0.0047726617,0.0012033901,0.000017459051,0.97245574,0.00005361684,0.0006019008,0.00011468904,0.0050448664],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99899966,0.00001579409,0.00014162953,0.0004365964,0.0001633785,0.00024294954],"domain_scores_gemma":[0.9994324,0.000027779992,0.00004884828,0.00037076627,0.00005769079,0.00006252314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001067077,0.00022630887,0.00019751364,0.00003695985,0.000037415393,0.000044943044,0.0001536034,0.00052472134,0.000006942334],"category_scores_gemma":[0.0001145816,0.00022215059,0.000073442025,0.000029512656,0.000036602418,8.633415e-7,0.00014681218,0.00013749077,0.000014807752],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021691827,0.000016511582,0.00003034226,0.00032634687,0.00010505055,0.000004058818,0.00003295249,0.000058844573,0.20837224,0.0000027275928,0.7058213,0.085207954],"study_design_scores_gemma":[0.00015958342,0.00010780239,0.000008821631,0.00003542388,0.000039503746,0.0000038010362,0.000015374464,0.000011303824,0.06477993,0.0000035813387,0.9345768,0.00025806885],"about_ca_topic_score_codex":0.0000096803415,"about_ca_topic_score_gemma":0.000012010198,"teacher_disagreement_score":0.22875552,"about_ca_system_score_codex":0.0000071298637,"about_ca_system_score_gemma":0.000077355304,"threshold_uncertainty_score":0.9059038},"labels":[],"label_agreement":null},{"id":"W2957215989","doi":"10.1101/707562","title":"P granules protect RNA interference genes from silencing by piRNAs","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Johns Hopkins University","keywords":"Piwi-interacting RNA; Argonaute; Gene silencing; RNA interference; RasiRNA; RNA-induced silencing complex; Biology; RNA; Trans-acting siRNA; Cell biology; Small RNA; RNA silencing; Germline; Genetics; Gene","score_opus":0.008209811899030665,"score_gpt":0.23185621682027496,"score_spread":0.2236464049212443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2957215989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9281012,0.012926242,0.056334667,0.000049079936,0.0012023243,0.00069891056,0.00054267125,0.00013031914,0.000014586871],"genre_scores_gemma":[0.9940724,0.0012704248,0.0034705526,0.0001050205,0.0007216328,0.00018233481,0.000006632915,0.00015178569,0.000019237716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974033,0.0000825839,0.00046163378,0.0012579388,0.00025366002,0.0005408625],"domain_scores_gemma":[0.9978256,0.000022282135,0.00024532984,0.0014821844,0.00021876078,0.00020580913],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023917317,0.00064350205,0.00049586355,0.00010238218,0.00008864357,0.00016170727,0.0007698069,0.00070896005,0.00003507287],"category_scores_gemma":[0.00011611729,0.0007010742,0.00020377849,0.0001275002,0.00007633634,0.000007673222,0.0007914289,0.00056017004,0.000054494813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028748575,0.00004178234,0.0015086323,0.00018640315,0.00015972817,0.000006227454,0.000007049742,0.0005752014,0.9966599,0.0000060414454,0.00080251537,0.000017780485],"study_design_scores_gemma":[0.0003428638,0.000091468784,0.0043020686,0.00030142273,0.0000689582,1.4959854e-8,0.000004626107,0.00048416227,0.9870517,0.000001263861,0.006518509,0.00083291304],"about_ca_topic_score_codex":0.00018456171,"about_ca_topic_score_gemma":0.000007044693,"teacher_disagreement_score":0.06597118,"about_ca_system_score_codex":0.00007094535,"about_ca_system_score_gemma":0.00027875553,"threshold_uncertainty_score":0.999544},"labels":[],"label_agreement":null},{"id":"W2957899377","doi":"10.1038/s41598-019-46129-4","title":"The AMPK system of salmonid fishes was expanded through genome duplication and is regulated by growth and immune status in muscle","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Fisheries and Oceans Canada","funders":"Biotechnology and Biological Sciences Research Council; University of Aberdeen; Research Councils UK","keywords":"AMPK; Biology; Gene; Protein kinase A; Transgene; Immune system; Oncorhynchus; Cell biology; Protein subunit; Genetics; Phosphorylation; Fishery","score_opus":0.0037603834728769385,"score_gpt":0.23045460720203478,"score_spread":0.22669422372915785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2957899377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99379915,0.0051464746,0.00013439739,0.00004319928,0.00037040008,0.00023005575,0.000005043269,0.0000062173,0.00026508956],"genre_scores_gemma":[0.99897236,0.00023292063,0.00008895703,0.0000041582794,0.000008949797,0.000009426963,0.000056134082,0.000008192941,0.0006189176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990935,0.000015498099,0.0002708656,0.00035327912,0.00010658115,0.0001603273],"domain_scores_gemma":[0.9993728,0.0000074105183,0.00011159067,0.0004293406,0.000047150264,0.000031742537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032181642,0.00007761625,0.00010762909,0.000021701475,0.00007004416,0.00005367407,0.0000528593,0.000057078407,0.0000021647406],"category_scores_gemma":[0.000024580859,0.0000613291,0.000022699776,0.00010774227,0.000097619064,0.0000058271257,0.00006625728,0.000031717143,3.9801463e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062531894,0.000007764256,0.005006802,0.00005301553,0.0000088064435,0.0000014350436,0.0002317939,0.000018158917,0.9940774,0.000012581936,0.00024414266,0.0003318355],"study_design_scores_gemma":[0.00020764704,0.000042915002,0.062431235,0.000029383944,0.000007676247,0.000043402633,0.00042356073,0.00016044083,0.9278606,0.00015192086,0.0085257385,0.000115461975],"about_ca_topic_score_codex":0.00008947506,"about_ca_topic_score_gemma":0.000011132782,"teacher_disagreement_score":0.06621679,"about_ca_system_score_codex":0.000007739379,"about_ca_system_score_gemma":0.000022047294,"threshold_uncertainty_score":0.2500928},"labels":[],"label_agreement":null},{"id":"W2957938624","doi":"10.1534/genetics.119.302351","title":"Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of <i>Saccharomyces cerevisiae</i>","year":2019,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Biology; CRISPR; Genetics; Cas9; Locus (genetics); Extrachromosomal DNA; Saccharomyces cerevisiae; Genome; Ribosomal DNA; Gene; Phylogenetics","score_opus":0.008621084429630724,"score_gpt":0.27857456197603403,"score_spread":0.2699534775464033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2957938624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948762,0.003876061,0.0004985124,0.00013238545,0.00008621108,0.00022219708,0.000015088213,0.0000015002993,0.0002918232],"genre_scores_gemma":[0.9984648,0.000542412,0.0008565704,0.000043766162,0.000057156718,0.0000051351967,0.0000058148003,0.000007597139,0.000016717244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929816,0.000044731314,0.00026385929,0.00017360758,0.00011496152,0.00010465964],"domain_scores_gemma":[0.99922836,0.000028418115,0.00015228175,0.0005170979,0.000060410533,0.000013432019],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023259707,0.000082663355,0.0001323973,0.000022523422,0.000016834494,0.000004410736,0.00024445113,0.000064569314,0.0000051634142],"category_scores_gemma":[0.00005335098,0.00005646236,0.000038578517,0.00011154255,0.00012352524,0.0000016119347,0.00007007857,0.00005574543,3.92521e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007003563,0.000014535196,0.04481414,0.000114491275,0.000013104347,6.21414e-8,0.00021421732,0.000507505,0.95252806,0.00040467086,0.00004736034,0.0013348701],"study_design_scores_gemma":[0.00018670462,0.00010434065,0.040537447,0.000038970236,0.000020639443,0.000006538026,0.00044618922,0.00010219098,0.95614475,0.00016027923,0.002187273,0.000064693806],"about_ca_topic_score_codex":0.00003403819,"about_ca_topic_score_gemma":0.000034816207,"teacher_disagreement_score":0.0042766896,"about_ca_system_score_codex":0.0000047506646,"about_ca_system_score_gemma":0.00003870896,"threshold_uncertainty_score":0.23024681},"labels":[],"label_agreement":null},{"id":"W2959428333","doi":"10.1016/j.dnarep.2019.102653","title":"IT’S 2 for the price of 1: Multifaceted ITS2 processing machines in RNA and DNA maintenance","year":2019,"lang":"en","type":"review","venue":"DNA repair","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; RNA; DNA; Computational biology; Genetics; Gene","score_opus":0.023750179407140963,"score_gpt":0.346612007281116,"score_spread":0.32286182787397505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2959428333","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041918326,0.9966326,0.0017491933,0.00004299109,0.00011399929,0.0008379688,0.000037757436,0.000012697521,0.00015363283],"genre_scores_gemma":[0.0015169354,0.9962453,0.0011030473,0.000046672605,0.00009214951,0.00011672237,0.00006426246,0.000042554067,0.00077235384],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990417,0.000025937357,0.000337721,0.0003327668,0.000065117085,0.0001967586],"domain_scores_gemma":[0.99938035,0.000058800644,0.00015414883,0.00032571788,0.00005416388,0.000026829397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024200355,0.00022241131,0.0005007641,0.00004429995,0.000027969467,0.000011552707,0.0001777438,0.00019384893,0.0000018904807],"category_scores_gemma":[0.0001661978,0.00014755032,0.00021815869,0.00009615891,0.00004044441,0.0000022581578,0.000094441544,0.0001054967,7.9762367e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022609445,0.00003061712,0.000020261989,0.024059363,0.00013238107,0.0000014093043,0.000116919786,0.00007244652,0.0037872496,0.000009254503,0.001387372,0.9703601],"study_design_scores_gemma":[0.00024551258,0.000055642053,0.00004077432,0.002114528,0.00012143292,0.000013230056,0.0000258855,0.0015333862,0.0007561348,0.000001976155,0.9948937,0.00019777384],"about_ca_topic_score_codex":0.000008066371,"about_ca_topic_score_gemma":0.000020756173,"teacher_disagreement_score":0.9935064,"about_ca_system_score_codex":0.000011055264,"about_ca_system_score_gemma":0.000085981,"threshold_uncertainty_score":0.6016928},"labels":[],"label_agreement":null},{"id":"W2960706662","doi":"10.1038/s41434-019-0091-6","title":"A next-generation sequencing method for gene doping detection that distinguishes low levels of plasmid DNA against a background of genomic DNA","year":2019,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Biology; Plasmid; DNA sequencing; DNA; genomic DNA; Gene; Genetics; Sequencing by ligation; Computational biology; DNA nanoball sequencing; Molecular biology; Genomic library; Virology; Base sequence","score_opus":0.060769216193680455,"score_gpt":0.3143895871252087,"score_spread":0.2536203709315282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2960706662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75172615,0.0010750085,0.2465482,0.000006602015,0.00024170718,0.00033032542,0.00003584854,0.000008710631,0.000027442753],"genre_scores_gemma":[0.97459394,0.0003519777,0.024461105,0.00006374059,0.00033132185,0.000030070738,0.000082456914,0.000039443643,0.000045958477],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903464,0.000045838893,0.0002869033,0.00031791264,0.00010340509,0.00021128918],"domain_scores_gemma":[0.99936163,0.000028104982,0.0001652937,0.00030983766,0.00009689111,0.000038241655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030698467,0.00017568203,0.00024044799,0.00005880266,0.000048064074,0.000018534476,0.00013466408,0.00012665101,0.000010513663],"category_scores_gemma":[0.000015386151,0.0001769924,0.0001450265,0.00006138624,0.000021548552,0.0000066193206,0.000033108758,0.00004466583,0.000001133055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008418534,0.000016467386,0.0001223323,0.000067345696,0.00009062176,1.8136726e-7,0.00015655471,0.010888049,0.9721206,0.000004473527,0.000005656701,0.01644353],"study_design_scores_gemma":[0.0008719819,0.0002907379,0.0010003715,0.000019100431,0.0000136849585,0.000005696795,0.00012992356,0.0120079,0.9851009,0.000019977033,0.00034993826,0.00018977506],"about_ca_topic_score_codex":0.000022638895,"about_ca_topic_score_gemma":0.000030047355,"teacher_disagreement_score":0.22286779,"about_ca_system_score_codex":0.000037313515,"about_ca_system_score_gemma":0.00006900914,"threshold_uncertainty_score":0.721754},"labels":[],"label_agreement":null},{"id":"W2961434543","doi":"10.1016/j.jmb.2019.07.015","title":"Gaining Insights into the Function of Post-Translational Protein Modification Using Genome Engineering and Molecular Cell Biology","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"Eidgenössische Technische Hochschule Zürich","keywords":"Biology; Cell biology; Phosphorylation; Kinase; Genome engineering; CRISPR; Cyclin-dependent kinase; Embryonic stem cell; Transcription factor; Gene; Computational biology; Genetics; Genome editing; Cell cycle","score_opus":0.006189061137723694,"score_gpt":0.2647641280240247,"score_spread":0.258575066886301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2961434543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76849854,0.005759124,0.22539674,0.00006211539,0.00010066458,0.00013968465,0.0000018310891,0.0000022569332,0.000039057777],"genre_scores_gemma":[0.99444157,0.00007689255,0.00528544,0.00006844422,0.000073059055,0.0000029980033,0.000027784123,0.000018605446,0.00000521107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999155,0.00008024257,0.00035948673,0.00018068792,0.00007676648,0.00014784666],"domain_scores_gemma":[0.99933827,0.000016174663,0.00022224209,0.00018440669,0.00019179296,0.000047140766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023334647,0.00013868019,0.00019265132,0.00012682723,0.000028853623,0.000007786013,0.00014954986,0.00017470795,0.00000513287],"category_scores_gemma":[0.000043637338,0.000109549714,0.00010356422,0.00008955861,0.000054434837,0.0000057267525,0.000051779054,0.00014419948,7.036456e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061901956,0.000015545547,0.00033483768,0.000031219737,0.00007658982,0.0000015199058,0.00012080801,0.027680442,0.97027934,0.00060896284,2.7026357e-7,0.00078854366],"study_design_scores_gemma":[0.00060794695,0.0007820144,0.0012583743,0.000022424405,0.000051711086,0.000028169903,0.00008267316,0.0039142543,0.99072677,0.00043060855,0.0019325471,0.0001625332],"about_ca_topic_score_codex":0.000008358146,"about_ca_topic_score_gemma":8.761404e-7,"teacher_disagreement_score":0.22594304,"about_ca_system_score_codex":0.000009855783,"about_ca_system_score_gemma":0.00006344009,"threshold_uncertainty_score":0.44673076},"labels":[],"label_agreement":null},{"id":"W2961677697","doi":"10.1101/701656","title":"The PAX3 and 7 homeodomains have evolved unique determinants that influence DNA-binding, structure and communication with the paired domain","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Homeobox; Biology; DNA; Genetics; Hox gene; Transcription factor; Binding site; DNA-binding domain; PAX3; Gene; Computational biology","score_opus":0.005724353221630559,"score_gpt":0.22572839042904985,"score_spread":0.2200040372074193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2961677697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99330044,0.0046200026,0.00096675224,0.00021836472,0.00009411693,0.00067344954,0.00009225105,0.00003219585,0.0000024375008],"genre_scores_gemma":[0.9956725,0.0023741894,0.0016484858,0.00008856613,0.000059679405,0.0000781302,0.0000013713808,0.00006745099,0.000009585531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985734,0.00015052894,0.00020562994,0.00055699167,0.00017678301,0.0003366672],"domain_scores_gemma":[0.9979941,0.00006810461,0.00022800388,0.0014586443,0.00014328808,0.000107830136],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040469432,0.0003884437,0.0002573009,0.00004374024,0.0003591452,0.00024192696,0.00053871784,0.00038305938,0.0000011021773],"category_scores_gemma":[0.00005326857,0.0002573291,0.000045996316,0.00007790096,0.00033030086,0.000009394911,0.00068563485,0.0004288309,7.232295e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000594049,0.000011982076,0.07197718,0.00015537297,0.00014004267,0.0000051062602,0.00005699854,0.00012046889,0.92729884,0.00006058243,0.00009462291,0.000019391064],"study_design_scores_gemma":[0.0006379988,0.000114839524,0.4114161,0.00026526724,0.000090343034,4.1718897e-7,0.00006405636,0.0003345423,0.57892466,0.0000061921874,0.007501427,0.000644129],"about_ca_topic_score_codex":0.000025575064,"about_ca_topic_score_gemma":0.0000984895,"teacher_disagreement_score":0.3483742,"about_ca_system_score_codex":0.000033344313,"about_ca_system_score_gemma":0.00014902533,"threshold_uncertainty_score":0.9999879},"labels":[],"label_agreement":null},{"id":"W2963604054","doi":"10.1038/s41586-019-1430-x","title":"A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene","year":2019,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Congenital muscular dystrophy; Downregulation and upregulation; Muscular dystrophy; Biology; Transgene; Skeletal muscle; Paralysis; Genetic enhancement; Cancer research; Molecular biology; Gene; Pathology; Endocrinology; Medicine; Genetics; Surgery","score_opus":0.0031886429674505565,"score_gpt":0.2553374320813964,"score_spread":0.25214878911394584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963604054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6575111,0.000864019,0.34101474,0.000012246373,0.00010465582,0.00029481787,0.000016925671,0.000004921365,0.00017656089],"genre_scores_gemma":[0.98124564,0.000005691076,0.017963951,0.00003650716,0.00011545139,0.000024899393,0.0003223122,0.000015004566,0.00027054476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948376,0.000007681356,0.000102739476,0.00019540486,0.000109226334,0.00010117924],"domain_scores_gemma":[0.9996421,0.000003850603,0.00003823071,0.00020776463,0.000082979874,0.000025109717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000066462664,0.00008188951,0.000089802365,0.000028328655,0.000014580807,0.0000051334023,0.000080348094,0.0005133842,0.0000062070335],"category_scores_gemma":[0.00001342711,0.00007767305,0.00008953831,0.00004534857,0.000008122908,0.0000017935629,0.000021431359,0.00014783604,9.973589e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044751858,0.000026032354,0.00022589107,0.000070166694,0.000046067762,2.1709309e-7,0.000032588305,0.03651785,0.96165735,0.00009405689,0.00009619049,0.0011888408],"study_design_scores_gemma":[0.0009539398,0.00016592574,0.005021617,0.0000058524806,0.000029600593,0.000012355823,0.000033845925,0.03306354,0.9582944,0.000120975244,0.0021371916,0.0001607743],"about_ca_topic_score_codex":0.0000021453889,"about_ca_topic_score_gemma":6.8987896e-7,"teacher_disagreement_score":0.32373452,"about_ca_system_score_codex":0.0000061071823,"about_ca_system_score_gemma":0.000015097732,"threshold_uncertainty_score":0.3959689},"labels":[],"label_agreement":null},{"id":"W2963839877","doi":"10.1038/s41467-019-11306-6","title":"FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":332,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"U.S. Army Medical Research Institute of Infectious Diseases; U.S. National Library of Medicine; University of Colorado School of Medicine, Anschutz Medical Campus; DHHS Office of the Secretary; Defense Threat Reduction Agency; Hamilton Health Sciences Foundation; Public Health Agency; Children's National Hospital; British Columbia Centre for Disease Control; Public Health England; National Institutes of Health; U.S. Department of Health and Human Services; U.S. Department of Energy; U.S. Department of Defense","keywords":"Computer science; Quality (philosophy); Genome; Database; Computational biology; Biology; Genetics; Gene","score_opus":0.030996344447294825,"score_gpt":0.35343641665724873,"score_spread":0.3224400722099539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963839877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97738224,0.017619876,0.0019148343,0.0016350015,0.00005894143,0.0008662404,0.00014817726,0.000020780279,0.00035391588],"genre_scores_gemma":[0.9873049,0.0012970123,0.010357321,0.00049381616,0.000020882624,0.00010994311,0.00019603538,0.000012882818,0.00020719826],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992574,0.00003610556,0.00014129175,0.0002749274,0.000115243274,0.00017506577],"domain_scores_gemma":[0.997559,0.0002937575,0.00006032472,0.0017499033,0.00025771747,0.000079298945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035963266,0.0001048039,0.00013702128,0.000064625376,0.00018457836,0.0000833175,0.00058065075,0.00011351215,0.0000040408795],"category_scores_gemma":[0.0007844573,0.000087554974,0.000030361145,0.00014130819,0.0001948601,0.00001925218,0.00030067647,0.00019295834,0.0000019292922],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022530017,0.00018229528,0.055539284,0.0000936896,0.00016707144,3.0816358e-7,0.00026043173,0.00005429289,0.9107466,0.028391153,0.0021926991,0.0021469006],"study_design_scores_gemma":[0.011344701,0.0006995969,0.25753197,0.00014508233,0.00020913333,0.000038878294,0.00060670107,0.0031183108,0.09688401,0.00021079801,0.6278606,0.0013502347],"about_ca_topic_score_codex":0.0000076256206,"about_ca_topic_score_gemma":0.0001404558,"teacher_disagreement_score":0.81386256,"about_ca_system_score_codex":0.000011849506,"about_ca_system_score_gemma":0.00013514509,"threshold_uncertainty_score":0.35703883},"labels":[],"label_agreement":null},{"id":"W2963853663","doi":"10.1007/s11248-019-00153-2","title":"Canadian regulatory aspects of gene editing technologies","year":2019,"lang":"en","type":"article","venue":"Transgenic Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Environment and Climate Change Canada; Health Canada; Canadian Food Inspection Agency","funders":"Health Canada; Environment and Climate Change Canada; Government of Canada","keywords":"Biology; Novelty; Biotechnology; Product (mathematics); Genome editing; Government (linguistics); Agency (philosophy); Gene; Genetics; CRISPR","score_opus":0.01884477464599851,"score_gpt":0.33795479200179657,"score_spread":0.3191100173557981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963853663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863321,0.0018303737,0.00035113934,0.00024429054,0.000102191145,0.00021414306,0.0000114197555,0.00001834604,0.010895952],"genre_scores_gemma":[0.9987509,0.00014144939,0.00035851554,0.0000061344745,0.000077750716,0.000010227088,0.000016656539,0.000017952756,0.0006203687],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989766,0.00002986528,0.00013225638,0.00023635123,0.00022568309,0.0003992473],"domain_scores_gemma":[0.99934936,0.000013296625,0.0000124877315,0.00043790595,0.000111665846,0.00007527058],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045055346,0.00007797457,0.000102146856,0.00016769934,0.000044277804,0.000008562521,0.0002827637,0.0001500461,0.000056052566],"category_scores_gemma":[0.00004972344,0.0000789163,0.00005772029,0.00019121672,0.000075195865,0.0000017859628,0.000030362346,0.00017093026,0.00002636793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009832478,0.000007395485,0.001625248,0.000045027027,0.000025490535,0.0000017723761,0.00004928905,0.00022788347,0.99456644,0.00038800226,0.00031825807,0.0027353743],"study_design_scores_gemma":[0.0002158446,0.00013772838,0.002916999,0.000014133035,0.0000027490573,0.0000048184347,0.0003344777,0.000052328094,0.98741734,0.00014851397,0.00866883,0.000086253865],"about_ca_topic_score_codex":0.0022251895,"about_ca_topic_score_gemma":0.0073045837,"teacher_disagreement_score":0.0124188,"about_ca_system_score_codex":0.000030073736,"about_ca_system_score_gemma":0.0002489367,"threshold_uncertainty_score":0.40761292},"labels":[],"label_agreement":null},{"id":"W2964043747","doi":"10.1080/17513758.2017.1314025","title":"Mathematical modelling of CRISPR-Cas system effects on biofilm formation","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Dynamics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Biofilm; Biology; Computational biology; Biological system; Biochemical engineering; Evolutionary biology; Genetics; Engineering; Bacteria; Gene","score_opus":0.022085554187236258,"score_gpt":0.29997446452217713,"score_spread":0.2778889103349409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964043747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5413018,0.00010704598,0.45797935,0.000037123267,0.00012251294,0.00005099617,0.0000050225203,0.0000026295786,0.00039354138],"genre_scores_gemma":[0.99442667,0.00014409651,0.0052157203,0.000014917714,0.00016714165,0.0000013188616,0.0000074653926,0.000007357444,0.000015285803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992748,0.000030127143,0.00035798314,0.000092529786,0.000114574825,0.00012999539],"domain_scores_gemma":[0.9992009,0.000035938458,0.0003600187,0.0002405021,0.00009868406,0.00006400152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002832473,0.00010666511,0.00023313727,0.00003867712,0.00006831352,0.000022702448,0.0002523988,0.00016939903,0.0000015466723],"category_scores_gemma":[0.00016450661,0.000072237075,0.00015253652,0.000016779602,0.000045694418,0.0000055474106,0.000059893824,0.00011359331,0.0000022923018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085112144,0.0003862623,0.003324807,0.0013592995,0.00031959228,0.000084409534,0.00013447445,0.08959684,0.8607112,0.016845396,0.00023771028,0.026148854],"study_design_scores_gemma":[0.00097066694,0.0024469797,0.003032947,0.00043838564,0.000059990347,0.00027021967,0.00016064696,0.37849456,0.61266345,0.001024146,0.00017883691,0.00025919976],"about_ca_topic_score_codex":9.92615e-7,"about_ca_topic_score_gemma":6.5774833e-7,"teacher_disagreement_score":0.45312494,"about_ca_system_score_codex":0.000026042506,"about_ca_system_score_gemma":0.0000117698755,"threshold_uncertainty_score":0.29457426},"labels":[],"label_agreement":null},{"id":"W2964875256","doi":"10.1093/bioinformatics/btz616","title":"MultiGuideScan: a multi-processing tool for designing CRISPR guide RNA libraries","year":2019,"lang":"en","type":"article","venue":"Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; RNA; Guide RNA; Computational biology; Genome; Computer science; Genome editing; Biology; Gene; Genetics","score_opus":0.015178518619465653,"score_gpt":0.29648346503472606,"score_spread":0.2813049464152604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964875256","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06936246,0.00078367285,0.92798376,0.00004282558,0.00024538347,0.00048081906,0.000022100156,0.000051313782,0.0010276779],"genre_scores_gemma":[0.3458267,0.000040264385,0.65129155,0.0003216921,0.00016101063,0.00004022621,0.000109030814,0.00004060314,0.002168944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902326,0.0000065533804,0.00038782245,0.00016432007,0.0001040803,0.00031396214],"domain_scores_gemma":[0.9994345,0.00002052568,0.00009679032,0.0002938999,0.00008891223,0.00006541148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016687938,0.00018411687,0.00016134736,0.00005105963,0.00008699045,0.00010201429,0.00019961513,0.00013600243,0.000011836207],"category_scores_gemma":[0.00013653305,0.00017561382,0.000099999364,0.000067733454,0.000028741904,0.000021606616,0.000095708274,0.000058812882,0.00002559515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011865706,0.00007495641,0.004521927,0.0013892098,0.00012730056,0.0000012784155,0.0015778971,0.009507883,0.85258883,0.00019118475,0.023437446,0.10646343],"study_design_scores_gemma":[0.001444189,0.00020123196,0.000611027,0.00008290309,0.00002927903,0.000009241661,0.0007464885,0.19955744,0.67407095,0.000014651822,0.12274331,0.00048927055],"about_ca_topic_score_codex":0.0000033740791,"about_ca_topic_score_gemma":0.0000017873817,"teacher_disagreement_score":0.2766922,"about_ca_system_score_codex":0.00001220803,"about_ca_system_score_gemma":0.00009676824,"threshold_uncertainty_score":0.71613234},"labels":[],"label_agreement":null},{"id":"W2964894801","doi":"10.1038/s41467-019-11105-z","title":"Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Associazione Italiana per la Ricerca sul Cancro; National Institute of General Medical Sciences; New York State Stem Cell Science; Dalhousie University; Irving Medical Center, Columbia University; Université Laval; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"CRISPR; Homology directed repair; Genome editing; Cas9; DNA; Computational biology; Enhancer; DNA repair; Biology; DNA damage; Embryonic stem cell; Cell biology; Genetics; Nucleotide excision repair; Gene; Transcription factor","score_opus":0.006354679423081003,"score_gpt":0.29903129532208633,"score_spread":0.29267661589900534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964894801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96482944,0.017119965,0.014118157,0.0004399096,0.00041343275,0.0006712161,0.000234527,0.00028040196,0.0018929647],"genre_scores_gemma":[0.98493385,0.00033055112,0.0126094585,0.000084418214,0.000029054512,0.000015140118,0.0018256183,0.000020956757,0.00015096604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993153,0.00008028885,0.00020158873,0.00019316176,0.00008071003,0.00012895859],"domain_scores_gemma":[0.9981726,0.000055607783,0.00006144868,0.0015101567,0.00014686852,0.000053337775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013956931,0.00011121824,0.00013212294,0.000054839027,0.00004402982,0.000005588089,0.0004448967,0.00035272192,0.00002355219],"category_scores_gemma":[0.0001362808,0.0001169405,0.00006601749,0.00016536817,0.000041854833,0.0000049770388,0.00012620667,0.0002787923,0.000008034237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033042557,0.0001692089,0.0030919893,0.000014899943,0.00008798339,3.7943173e-7,0.00007033111,0.0017517902,0.98703283,0.00044312072,0.0070244777,0.000279939],"study_design_scores_gemma":[0.0031201025,0.0011936895,0.09489386,0.00006147237,0.00018037608,0.00005957799,0.00021785755,0.21751961,0.4553313,0.00012148321,0.22619411,0.0011065727],"about_ca_topic_score_codex":0.000015191653,"about_ca_topic_score_gemma":0.000047987924,"teacher_disagreement_score":0.53170156,"about_ca_system_score_codex":0.000010110309,"about_ca_system_score_gemma":0.00003485579,"threshold_uncertainty_score":0.47686952},"labels":[],"label_agreement":null},{"id":"W2965106952","doi":"10.1101/725465","title":"Spatial and temporal control of CRISPR/Cas9-mediated gene editing delivered via a light-triggered liposome system","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"Macquarie University; Heart Research Institute","keywords":"CRISPR; Genome editing; Cas9; Gene knockout; Computational biology; Biology; Gene; HEK 293 cells; Zebrafish; Genetics","score_opus":0.004626513358633309,"score_gpt":0.21006213606183188,"score_spread":0.20543562270319857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2965106952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87307346,0.00612301,0.11758306,0.000051250358,0.0014740264,0.000950525,0.0006188398,0.00011997378,0.0000058571013],"genre_scores_gemma":[0.9966035,0.00022976467,0.0016785124,0.00004513235,0.0011989521,0.0000908055,0.0000075631046,0.0001423273,0.0000034333614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972382,0.000119155855,0.00075596647,0.0010169884,0.00032694804,0.00054272724],"domain_scores_gemma":[0.9975929,0.000034489807,0.00053483073,0.0010709957,0.0004974954,0.0002692864],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004279491,0.00061827205,0.0008244017,0.00019238998,0.000080943915,0.000075576325,0.00040795188,0.0008417336,0.000007116095],"category_scores_gemma":[0.00015320012,0.00067439553,0.00020724804,0.00016117294,0.00007955325,0.000008391735,0.00046032452,0.00041163006,0.000012643884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102666854,0.000053333042,0.00961502,0.0009876139,0.00033696674,0.000024099758,0.000008796542,0.0004030674,0.9883739,0.000008520898,0.00008185142,0.0000041673907],"study_design_scores_gemma":[0.0018797147,0.00020730047,0.015002171,0.00039183802,0.0002226892,2.854836e-7,0.000009027615,0.008458393,0.9718236,1.5367311e-7,0.0012339691,0.0007709025],"about_ca_topic_score_codex":0.00018038992,"about_ca_topic_score_gemma":0.0000073008514,"teacher_disagreement_score":0.12353005,"about_ca_system_score_codex":0.00007736567,"about_ca_system_score_gemma":0.00029609498,"threshold_uncertainty_score":0.9995707},"labels":[],"label_agreement":null},{"id":"W2967820651","doi":"10.1007/s12687-019-00430-x","title":"Human germline genome editing is illegal in Canada, but could it be desirable for some members of the rare disease community?","year":2019,"lang":"en","type":"review","venue":"Journal of Community Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre","funders":"","keywords":"Germline; Context (archaeology); Genome editing; Disease; Community engagement; Genome; Public health; Genetics; Biology; Public relations; Political science; Medicine; Gene","score_opus":0.07120412190383961,"score_gpt":0.3650235738592013,"score_spread":0.2938194519553617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2967820651","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07463816,0.9231237,0.00013918539,0.00017283451,0.0005074218,0.0006180284,0.00073330593,0.0000018015875,0.00006555957],"genre_scores_gemma":[0.09282638,0.9049664,0.0003875509,0.00056746975,0.00052084285,0.000015784275,0.00024647586,0.00010944147,0.00035961551],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972404,0.000742943,0.0012172633,0.00010708021,0.00034469753,0.0003475656],"domain_scores_gemma":[0.9970736,0.00019426853,0.0010040915,0.0012596926,0.00029797427,0.00017039054],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010379226,0.00038379873,0.0011295669,0.00012320957,0.00029351172,0.00002685469,0.0016579692,0.00022450124,0.000014251251],"category_scores_gemma":[0.00021268264,0.0003167017,0.0006161128,0.00014443723,0.00009461424,0.000006296243,0.00053721876,0.0016715804,1.860313e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081181637,0.0050251116,0.004179574,0.31520376,0.011891528,0.0001448981,0.009065689,0.16992891,0.043189574,0.000210231,0.14927399,0.29107493],"study_design_scores_gemma":[0.0009204663,0.0003556422,0.00045027625,0.0032668477,0.0009936151,0.00006706163,0.0014414056,0.000069967165,0.0013551856,0.000046427213,0.9905238,0.0005093133],"about_ca_topic_score_codex":0.020950487,"about_ca_topic_score_gemma":0.09754297,"teacher_disagreement_score":0.8412498,"about_ca_system_score_codex":0.00021661444,"about_ca_system_score_gemma":0.0021639194,"threshold_uncertainty_score":0.99992853},"labels":[],"label_agreement":null},{"id":"W2967946563","doi":"10.15252/msb.20188679","title":"CRISPR screens are feasible in TP53 wild‐type cells","year":2019,"lang":"en","type":"letter","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; University of Toronto","funders":"","keywords":"Library science; Computer science","score_opus":0.010495376489887657,"score_gpt":0.2958816565517814,"score_spread":0.28538628006189376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2967946563","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25297305,0.28410003,0.19238612,0.1628643,0.057216853,0.015978329,0.0025708138,0.00074449135,0.031165987],"genre_scores_gemma":[0.7890424,0.0012837362,0.0006202886,0.1862844,0.006289167,0.00024204401,0.0048835278,0.00053342857,0.010821017],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968797,0.00033211053,0.00058609946,0.0011380907,0.0001895482,0.0008744319],"domain_scores_gemma":[0.9982621,0.000029054803,0.00025379687,0.0012325406,0.00014923126,0.000073290976],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00025436375,0.0006316976,0.0008185131,0.00028112315,0.000037713733,0.000045238816,0.00062770076,0.002376665,0.0000127392],"category_scores_gemma":[0.000058766684,0.00064240413,0.00024970024,0.00022593624,0.00008519611,0.0000029030377,0.00026831072,0.00095546036,0.000115068324],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026510286,0.000023847078,0.00076404674,0.0004051465,0.00016435859,0.00035482986,0.0000129976925,0.0029927639,0.44356874,0.000027349288,0.55158657,0.00007284973],"study_design_scores_gemma":[0.0005877236,0.0003450624,0.00008817822,0.00018251615,0.00004932179,0.00009446469,0.000032668097,0.00028058098,0.055486158,0.00001980043,0.9419978,0.00083572627],"about_ca_topic_score_codex":0.0004047571,"about_ca_topic_score_gemma":0.000057377325,"teacher_disagreement_score":0.53606933,"about_ca_system_score_codex":0.000057649846,"about_ca_system_score_gemma":0.00013242672,"threshold_uncertainty_score":0.99960274},"labels":[],"label_agreement":null},{"id":"W2968408741","doi":"10.1007/978-3-030-17119-3_8","title":"Comparative Analysis: The Regulation of Plants Derived from Genome Editing in Argentina, Australia, Canada, the European Union, Japan and the United States","year":2019,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung","keywords":"Sect; Diversity (politics); European union; Political science; Genome; Biology; Biotechnology; Geography; Law; Genetics; Business; International trade; Gene","score_opus":0.014939447514554937,"score_gpt":0.24964490708686068,"score_spread":0.23470545957230574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968408741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97669005,0.0017200256,0.0017770674,0.0003816791,0.00013371318,0.0005371588,0.00036948218,0.000005228593,0.018385598],"genre_scores_gemma":[0.978354,0.0002254261,0.00002096215,0.00006528617,0.000117186966,0.0000021543249,0.0019471269,0.000012868312,0.019254997],"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","domain_scores_codex":[0.99909157,0.00015900987,0.0002853339,0.00021375576,0.00012651968,0.00012378824],"domain_scores_gemma":[0.9993192,0.00007446476,0.00017699921,0.00034581532,0.000059343227,0.000024161887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039008458,0.00017914778,0.0002501425,0.00005387403,0.00005867266,0.000019113677,0.0002102239,0.00006648313,0.000043862998],"category_scores_gemma":[0.000007894806,0.00009585784,0.00006565202,0.00004889736,0.00012775768,0.0000012025831,0.00010119292,0.00014363845,0.0000011284797],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005424449,0.000066320565,0.013349301,0.0002009443,0.019836873,0.0000138184805,0.015199474,0.6541228,0.27584216,0.0073787267,0.01170067,0.0017464445],"study_design_scores_gemma":[0.0027932997,0.000118054006,0.790742,0.00017639944,0.002170898,0.000009371365,0.0070223934,0.012976245,0.028093899,0.0008099039,0.15395302,0.001134548],"about_ca_topic_score_codex":0.10922977,"about_ca_topic_score_gemma":0.39446795,"teacher_disagreement_score":0.7773927,"about_ca_system_score_codex":0.000010205211,"about_ca_system_score_gemma":0.000038767244,"threshold_uncertainty_score":0.89670193},"labels":[],"label_agreement":null},{"id":"W2968534099","doi":"10.1007/978-1-4939-9674-2_16","title":"Visualizing Transcription Factor Binding on Mitotic Chromosomes Using Single-Molecule Live-Cell Imaging","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Mitosis; Cell biology; Biology; Embryonic stem cell; Transcription factor; Live cell imaging; Cell division; Cell; Genetics; Gene","score_opus":0.02320409415888272,"score_gpt":0.40283597541391886,"score_spread":0.3796318812550361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968534099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5657212,0.0010721569,0.43226096,0.0000169484,0.0003966606,0.00020232808,0.000006386899,0.00001842734,0.00030491597],"genre_scores_gemma":[0.7957822,0.000042475407,0.20367588,0.00020388684,0.00008532983,0.000012602955,0.00005225196,0.00006600845,0.00007933561],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99775636,0.00050927786,0.0003707977,0.0007157047,0.00010158384,0.0005462683],"domain_scores_gemma":[0.99928224,0.000054317523,0.000096428565,0.00044264807,0.000040206825,0.0000841859],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041386922,0.0003314755,0.00033958344,0.00025676013,0.00004921695,0.000031395095,0.00025157665,0.00025500703,0.00005287668],"category_scores_gemma":[0.000106115454,0.0003504084,0.00018224178,0.00020879906,0.00006164911,0.000005517672,0.00009924909,0.00022827029,0.000020087047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003108951,0.000078704325,0.0033096548,0.00004772893,0.000026385871,0.000012682273,0.00010347657,0.001677615,0.99183273,0.00005820719,0.0000030028732,0.0028187404],"study_design_scores_gemma":[0.000722431,0.00034405245,0.00020836735,0.000054945704,0.000019246512,0.000023466833,0.00012307409,0.0034345577,0.99361265,0.00006209513,0.0009850579,0.00041003822],"about_ca_topic_score_codex":0.000020587475,"about_ca_topic_score_gemma":0.0000031583695,"teacher_disagreement_score":0.23006101,"about_ca_system_score_codex":0.000067331806,"about_ca_system_score_gemma":0.000038216112,"threshold_uncertainty_score":0.9998948},"labels":[],"label_agreement":null},{"id":"W2968665392","doi":"10.1186/s12915-019-0685-x","title":"Synthetic Biology Goes Cell-Free","year":2019,"lang":"en","type":"review","venue":"BMC Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; International Development Research Centre","keywords":"Synthetic biology; Biology; Systems biology; Scope (computer science); Key (lock); Computational biology; Biochemical engineering; Nanotechnology; Computer science; Ecology; Engineering","score_opus":0.03155118434071593,"score_gpt":0.3794506449125352,"score_spread":0.3478994605718193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968665392","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052745774,0.98969495,0.0062642535,0.000009923017,0.001202682,0.0005220756,0.00022788414,0.000035388417,0.001990096],"genre_scores_gemma":[0.00028529263,0.9946437,0.0014309464,0.00004522747,0.00068403414,0.000110122324,0.0011361119,0.00009567748,0.0015688817],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99766815,0.0002352551,0.0005257739,0.00095583923,0.00004455093,0.0005704239],"domain_scores_gemma":[0.99802434,0.00008254782,0.0002088566,0.0015426638,0.000040001414,0.00010156213],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00020805867,0.0005736296,0.0012653229,0.00014222802,0.000044785207,0.000013942368,0.0009595609,0.001349882,0.00008200782],"category_scores_gemma":[0.0001702316,0.0004611586,0.00061919494,0.00011471442,0.00014488793,8.9615787e-7,0.00061018503,0.00028044893,0.0003262789],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027617298,0.00013434887,0.00013502248,0.01790447,0.00045172163,0.000004271417,0.000016481152,0.000025227773,0.008936771,0.0013838006,0.0056149927,0.9653653],"study_design_scores_gemma":[0.00025016794,0.00028187662,0.000003865552,0.0003216803,0.00028092664,0.00005342602,0.000004809628,0.0000043038867,0.0006672686,0.000082308514,0.9975063,0.0005430738],"about_ca_topic_score_codex":0.000015026349,"about_ca_topic_score_gemma":0.000018228058,"teacher_disagreement_score":0.9918913,"about_ca_system_score_codex":0.000022182208,"about_ca_system_score_gemma":0.00026427727,"threshold_uncertainty_score":0.9999466},"labels":[],"label_agreement":null},{"id":"W2968863659","doi":"10.1080/15476286.2019.1649586","title":"Todos Santos small RNA symposium","year":2019,"lang":"pt","type":"article","venue":"RNA Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; National Institute of General Medical Sciences; University of New England; Colorado State University","keywords":"Biology; Genealogy; Library science; Environmental ethics; History; Computer science","score_opus":0.008162436029140225,"score_gpt":0.29142412646906707,"score_spread":0.2832616904399268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968863659","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96891403,0.009450374,0.00595381,0.000616416,0.0028920595,0.00052090385,0.00009566879,0.00003936774,0.011517395],"genre_scores_gemma":[0.9852239,0.0019054057,0.00026506817,0.00047615528,0.0007858579,0.000018636478,0.00024140363,0.00006238426,0.011021222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785715,0.00010573464,0.0004082237,0.00080941414,0.0000740847,0.0007453743],"domain_scores_gemma":[0.9987581,0.000034121873,0.000118733995,0.0008171608,0.000081977494,0.00018994599],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020011584,0.00041825796,0.0004461425,0.000087545595,0.000062987005,0.000029001181,0.00045973665,0.00075361796,0.000423755],"category_scores_gemma":[0.00004016671,0.00041457952,0.0002431593,0.00011769602,0.0000894967,0.0000024723727,0.00032562023,0.00026361877,0.0006360182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007724647,0.000051035327,0.0036364114,0.00009941244,0.00017909441,0.0000056803547,0.00013367947,0.00030051952,0.98987854,0.00018811622,0.001360974,0.004089287],"study_design_scores_gemma":[0.0013191988,0.0013661886,0.001548146,0.00005262275,0.000082843966,0.000052633794,0.00016414605,0.0008019652,0.7986118,0.00003779041,0.19517234,0.0007903217],"about_ca_topic_score_codex":0.000051514315,"about_ca_topic_score_gemma":0.00004053412,"teacher_disagreement_score":0.19381136,"about_ca_system_score_codex":0.000029224275,"about_ca_system_score_gemma":0.000105655585,"threshold_uncertainty_score":0.9998306},"labels":[],"label_agreement":null},{"id":"W2969219984","doi":"10.1039/c9cc04226a","title":"Beacon-mediated exponential amplification reaction (BEAR) using a single enzyme and primer","year":2019,"lang":"en","type":"article","venue":"Chemical Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Health; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Primer (cosmetics); Exponential function; Enzyme; Chemistry; Combinatorial chemistry; Biochemistry; Mathematics; Organic chemistry","score_opus":0.024587747738744295,"score_gpt":0.3058020218954223,"score_spread":0.28121427415667805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969219984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99399936,0.0010668768,0.003964866,0.00014518385,0.000046887468,0.00014454145,0.000007167167,0.000021151194,0.0006039693],"genre_scores_gemma":[0.9946088,0.0001339658,0.0046438733,0.00004563468,0.00005094772,0.000012492952,0.00041176318,0.00001548211,0.00007705018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949926,0.00002166863,0.00013856938,0.00017388235,0.000055378598,0.00011121599],"domain_scores_gemma":[0.9991159,0.000026567262,0.000043583732,0.00071264594,0.00004800615,0.000053338215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006322675,0.0000814964,0.00007579261,0.000025199792,0.000050545954,0.000017077075,0.00018327862,0.000103241255,0.0000067499495],"category_scores_gemma":[0.000058150847,0.000091324015,0.000032093936,0.00006542665,0.00006263904,0.000005029593,0.00017814581,0.00009608441,0.000012966553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008385569,0.000045404984,0.00032648136,0.000006985684,0.0000135399005,2.5007651e-8,0.000035805326,0.000010459837,0.9989132,0.000042707445,0.00005698506,0.00053997844],"study_design_scores_gemma":[0.00026693055,0.000027003822,0.0011058201,0.000012111416,0.000018945479,0.000009882223,0.000060282116,0.0019527122,0.97859025,0.000024733368,0.017794317,0.00013701459],"about_ca_topic_score_codex":0.000016772054,"about_ca_topic_score_gemma":0.0000025088816,"teacher_disagreement_score":0.020322993,"about_ca_system_score_codex":0.000017126655,"about_ca_system_score_gemma":0.000017375396,"threshold_uncertainty_score":0.3724085},"labels":[],"label_agreement":null},{"id":"W2969238338","doi":"10.1186/s13059-019-1776-2","title":"Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation","year":2019,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; McGill University Health Centre","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences; Biotechnology and Biological Sciences Research Council; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Medical Research Council; University of California, Davis; Directorate for Biological Sciences; National Institutes of Health; Akademie Věd České Republiky; Indiana Clinical and Translational Sciences Institute; Ministerstvo Školství, Mládeže a Tělovýchovy; Ministry of Education, Culture, Sports, Science and Technology; McGill University; McGill University Health Centre; National Cancer Institute; British Heart Foundation; National Center for Advancing Translational Sciences; Wellcome Trust; Japan Agency for Medical Research and Development; Canadian Institutes of Health Research; Royal Society; Wellcome","keywords":"CRISPR; Biology; Cas9; Conditional gene knockout; Genome editing; Genetics; Homologous recombination; Computational biology; Allele; Gene; Phenotype","score_opus":0.06423970125261735,"score_gpt":0.4498523355932214,"score_spread":0.38561263434060405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969238338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6073961,0.0008594191,0.3909902,0.0000215056,0.00013736782,0.000447134,0.00011956678,0.0000029753446,0.000025709189],"genre_scores_gemma":[0.9381465,0.000049835813,0.0596907,0.00003647281,0.00012975086,0.00006197019,0.0017708285,0.000010798023,0.000103142644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884665,0.00013521308,0.00030075217,0.0005455561,0.00004505732,0.0001267553],"domain_scores_gemma":[0.9989288,0.00002160179,0.000115177274,0.00062870956,0.00028168698,0.00002404191],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014276891,0.00009282714,0.00018323393,0.000042078274,0.000015426773,0.0000018331252,0.00009454103,0.00013402,0.000055855642],"category_scores_gemma":[0.0003418393,0.00008935623,0.00009661983,0.00003402194,0.000048399877,0.0000019068447,0.000046919118,0.000029785251,0.000001966766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048954065,0.00009511747,0.0020504212,0.000045384713,0.000061641666,8.9964445e-9,0.000048990074,0.0015182312,0.9933602,0.00007406657,0.000052064974,0.0026449068],"study_design_scores_gemma":[0.0013890694,0.00044004715,0.004515103,0.000001912402,0.000024694975,0.0000022875122,0.000028548668,0.006062658,0.98067003,0.00010181503,0.0066560176,0.00010781311],"about_ca_topic_score_codex":0.0000072060116,"about_ca_topic_score_gemma":0.0000074836794,"teacher_disagreement_score":0.33129948,"about_ca_system_score_codex":0.000012899475,"about_ca_system_score_gemma":0.000053797175,"threshold_uncertainty_score":0.36438414},"labels":[],"label_agreement":null},{"id":"W2969520863","doi":"10.1128/msphere.00408-19","title":"Single-Strand Annealing Plays a Major Role in Double-Strand DNA Break Repair following CRISPR-Cas9 Cleavage in <i>Leishmania</i>","year":2019,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"CRISPR; Biology; Genome editing; DNA repair; Cas9; DNA; Non-homologous end joining; Genetics; Gene; Guide RNA; Computational biology; Cell biology","score_opus":0.0061694635803404415,"score_gpt":0.2483449875310197,"score_spread":0.24217552395067926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969520863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98860765,0.002237884,0.00034285983,0.000044485285,0.00023971962,0.0003775786,0.000013838926,0.000045043722,0.008090955],"genre_scores_gemma":[0.99831545,0.000041189967,0.0006426109,0.000115198374,0.00013339004,0.000022039403,0.00005576186,0.00005533804,0.0006190224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836236,0.000034470777,0.0003833202,0.00055827026,0.0001588301,0.00050277356],"domain_scores_gemma":[0.99938977,0.000017503262,0.000048945578,0.0004271988,0.000018507704,0.000098067234],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024829287,0.00026779203,0.0003030082,0.0000580482,0.000038482664,0.000045562698,0.00020001706,0.00026269912,0.000049249793],"category_scores_gemma":[0.000016252583,0.00029277185,0.00019385661,0.00018539913,0.000019695459,0.000012808778,0.00008011729,0.00021239597,0.000023545823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035745173,0.00011910368,0.07143614,0.00012447881,0.000058388934,0.00008303136,0.0003780532,0.004320124,0.92151576,0.000015993272,0.00050066836,0.0010908308],"study_design_scores_gemma":[0.0091318,0.0004330073,0.018673826,0.00029512297,0.000046634308,0.000049942733,0.001261126,0.0017384625,0.94357026,0.000049872662,0.023823649,0.0009263118],"about_ca_topic_score_codex":0.00024482567,"about_ca_topic_score_gemma":0.0019155446,"teacher_disagreement_score":0.052762315,"about_ca_system_score_codex":0.000035257555,"about_ca_system_score_gemma":0.00003904911,"threshold_uncertainty_score":0.99995244},"labels":[],"label_agreement":null},{"id":"W2969792006","doi":"10.1093/nar/gkz721","title":"The autoregulator Aca2 mediates anti-CRISPR repression","year":2019,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Marsden Fund; Royal Society Te Apārangi; University of Toronto; University of Otago","keywords":"CRISPR; Biology; CRISPR interference; Inverted repeat; Genetics; Gene; Operon; DNA; Psychological repression; Trans-activating crRNA; Cas9; Direct repeat; Gene expression; Genome; Mutant","score_opus":0.01602297028132943,"score_gpt":0.36133207887000285,"score_spread":0.3453091085886734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969792006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99323034,0.002030036,0.00018096142,0.00046486108,0.0003179097,0.00027066912,0.000004291291,0.000023794963,0.003477123],"genre_scores_gemma":[0.9937056,0.0006223858,0.00019214953,0.00002798326,0.0003423001,0.000020754545,0.000018233179,0.00003400808,0.0050365995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983916,0.00010612716,0.00016257998,0.00037836985,0.00045978912,0.0005014876],"domain_scores_gemma":[0.99884176,0.00007236234,0.000023204935,0.0007981536,0.0001490333,0.000115457806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091835874,0.00011730223,0.00010823708,0.000050895083,0.00024317382,0.00007621789,0.00049122755,0.00016602376,0.00010418166],"category_scores_gemma":[0.00025913687,0.00008139679,0.0000704381,0.0001649225,0.00014033966,0.0000038600697,0.0003988087,0.00028084515,0.0002475921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004296965,0.000020483307,0.009425287,0.000020179941,0.00002729527,0.0000020950079,0.00007109024,0.0002054613,0.96787655,0.00016197306,0.01549488,0.0066517363],"study_design_scores_gemma":[0.00044794165,0.00022900852,0.049060255,0.000026320975,0.000004200685,0.000009303049,0.00029023743,0.0018757964,0.5670599,0.00011734164,0.38068497,0.00019476096],"about_ca_topic_score_codex":0.000012389689,"about_ca_topic_score_gemma":0.0000040822206,"teacher_disagreement_score":0.40081668,"about_ca_system_score_codex":0.000017584389,"about_ca_system_score_gemma":0.00006693749,"threshold_uncertainty_score":0.33192647},"labels":[],"label_agreement":null},{"id":"W2969976636","doi":"10.1038/s41467-019-11695-8","title":"High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of Allergy and Infectious Diseases; School of Medicine, New York University; National Institutes of Health; National Institute of General Medical Sciences; Chinese Academy of Sciences; University of Toronto; Universität Wien; National Natural Science Foundation of China; York University; Foundation for the National Institutes of Health","keywords":"CRISPR; Trans-activating crRNA; Biology; CRISPR interference; Genetics; RNA; Computational biology; Cas9; Transcription (linguistics); Gene","score_opus":0.009191911747329676,"score_gpt":0.3220201580942142,"score_spread":0.3128282463468845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969976636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95847976,0.021216238,0.009777681,0.0063461713,0.000488562,0.0009295069,0.00019874041,0.00011170561,0.0024516624],"genre_scores_gemma":[0.96088094,0.00034367567,0.03574209,0.00059590454,0.00014680717,0.000039941104,0.00073196617,0.000040866937,0.0014778017],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998801,0.00009600235,0.00030286593,0.00038792187,0.00015826219,0.00025394815],"domain_scores_gemma":[0.9977371,0.000066143606,0.00010729168,0.0018201073,0.00018439948,0.00008494035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030638,0.00017890417,0.00017392878,0.00006867884,0.00018732487,0.00004433814,0.0007930669,0.00035039074,0.000020429827],"category_scores_gemma":[0.0003259973,0.00019101515,0.0000821632,0.00022273055,0.000038091897,0.000010189944,0.0004885029,0.00031600567,0.000028684064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009921012,0.000034425702,0.0036984421,0.00001575996,0.000037035228,1.4368413e-7,0.00010429531,0.00064742315,0.9589012,0.00022677844,0.034041554,0.0022830002],"study_design_scores_gemma":[0.00048323977,0.00010997862,0.015939131,0.0000864223,0.000047052526,0.000008116426,0.00028262468,0.00067368965,0.7793133,0.000069513866,0.20243183,0.0005550631],"about_ca_topic_score_codex":0.000076833705,"about_ca_topic_score_gemma":0.000057305882,"teacher_disagreement_score":0.17958789,"about_ca_system_score_codex":0.000027696178,"about_ca_system_score_gemma":0.000022214323,"threshold_uncertainty_score":0.77893716},"labels":[],"label_agreement":null},{"id":"W2970071674","doi":"10.1016/j.cell.2019.07.046","title":"Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription","year":2019,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; CRISPR; Gene; Repressor; Transcription (linguistics); Genetics; Promoter; DNA; Transcription factor; Genome; CRISPR interference; DNA-binding protein; Conserved sequence; Cell biology; Computational biology; Cas9; Gene expression; Peptide sequence","score_opus":0.006435162014956998,"score_gpt":0.24800023516695752,"score_spread":0.24156507315200051,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970071674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943883,0.00082475477,0.00251315,0.00004051017,0.00034630467,0.0003538602,0.000033880482,0.00002205415,0.0014772252],"genre_scores_gemma":[0.9980998,0.00016575796,0.0002470088,0.000034543496,0.00010603521,0.000010472631,0.000072910814,0.000030415258,0.0012330469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900717,0.00003521184,0.00024407293,0.00033397644,0.00013794542,0.00024159995],"domain_scores_gemma":[0.9993714,0.0000049839414,0.00011391642,0.00036866753,0.000084035186,0.00005701502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012644836,0.0001572739,0.00024001354,0.000045190987,0.00003148077,0.000012323486,0.00016607501,0.00019525501,0.000055689456],"category_scores_gemma":[0.00003253551,0.00016357668,0.00013844822,0.00009545031,0.000030465575,0.000003961749,0.00004180465,0.00010004027,0.000021863756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002070463,0.00010868982,0.0067911693,0.00009286525,0.000027995906,0.0000017465208,0.00009444407,0.0011548786,0.99101406,0.0000043451655,0.0005751888,0.00011393587],"study_design_scores_gemma":[0.0007434439,0.00015256472,0.02965566,0.000038124537,0.000026094307,0.000001717768,0.00009694102,0.00017922604,0.9646497,0.000010467055,0.0042515886,0.00019448658],"about_ca_topic_score_codex":0.000032899185,"about_ca_topic_score_gemma":0.000014823319,"teacher_disagreement_score":0.02636435,"about_ca_system_score_codex":0.000009653824,"about_ca_system_score_gemma":0.000034556168,"threshold_uncertainty_score":0.6670463},"labels":[],"label_agreement":null},{"id":"W2970990602","doi":"10.1007/978-981-13-8367-0_15","title":"Application of CRISPR-Cas9 Screening Technologies to Study Mitochondrial Biology in Healthy and Disease States","year":2019,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"CRISPR; Cas9; Biology; Computational biology; Disease; Mitochondrial disease; Genome editing; Mitochondrial DNA; Genetics; Gene; Medicine; Pathology","score_opus":0.029668137768321928,"score_gpt":0.4625659086004975,"score_spread":0.43289777083217557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970990602","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0099906735,0.9854339,0.003125996,0.000076351345,0.0001821726,0.0011504649,0.000021871443,0.000009287043,0.0000092892915],"genre_scores_gemma":[0.13219653,0.8665422,0.0006768238,0.000048391412,0.0000833322,0.00027709466,0.00015875354,0.000014884812,0.000001946028],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861825,0.000082903935,0.00047271105,0.0005701207,0.000035057863,0.0002209693],"domain_scores_gemma":[0.9994835,0.000064079795,0.00012096161,0.00024911025,0.000013518421,0.000068794805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110610454,0.00025730385,0.00081715244,0.00023691346,0.000018110768,0.000001923286,0.00015299425,0.00019142739,0.0000014728731],"category_scores_gemma":[0.00010464301,0.00019453946,0.00003435294,0.00015810267,0.00019410436,0.000003950647,0.00023245146,0.00012855593,3.8298725e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024283107,0.00014135508,0.004982936,0.0010643803,0.00003444558,0.0000024526175,0.0001876854,0.000012818121,0.00759998,0.00009150634,0.000010294062,0.9856293],"study_design_scores_gemma":[0.004134444,0.012866219,0.00029450472,0.0023053943,0.00016789645,0.000026380034,0.0064898944,0.000071261675,0.0033403141,0.00043921656,0.96894234,0.0009221336],"about_ca_topic_score_codex":0.000059313043,"about_ca_topic_score_gemma":0.00004050197,"teacher_disagreement_score":0.9847072,"about_ca_system_score_codex":0.000013111923,"about_ca_system_score_gemma":0.000024505505,"threshold_uncertainty_score":0.7933089},"labels":[],"label_agreement":null},{"id":"W2971177113","doi":"10.1038/s41576-019-0156-9","title":"Leveraging European infrastructures to access 1 million human genomes by 2022","year":2019,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; Ontario Institute for Cancer Research","funders":"Wellcome Trust","keywords":"Biology; Genome; Computational biology; Evolutionary biology; Genetics; Gene","score_opus":0.030951528305866272,"score_gpt":0.40116952442908616,"score_spread":0.3702179961232199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971177113","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000049505594,0.9946501,0.0013700316,0.000012648167,0.000818875,0.0017135186,0.0001407698,0.000024292083,0.0012202555],"genre_scores_gemma":[0.000052711108,0.9936577,0.0010629457,0.0004795116,0.0011498568,0.000069720416,0.0018393907,0.00022048685,0.0014676824],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99681324,0.00035168746,0.0009305153,0.0010786139,0.00028133002,0.00054460735],"domain_scores_gemma":[0.99792576,0.00001695231,0.00037365884,0.0013627093,0.00008148164,0.0002394437],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048817298,0.0008732422,0.0016024925,0.00020047712,0.00011605873,0.00014845778,0.001462974,0.00082168856,0.00007479489],"category_scores_gemma":[0.00007906053,0.00074010034,0.0006947189,0.00039678035,0.000030457353,0.0000035215323,0.0008621199,0.00098283,0.00012312795],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000013106786,0.000012265321,0.0000115172825,0.0071173687,0.00010463778,0.0000028203365,0.000016535365,0.00004867825,0.0025672482,0.0000019954484,0.07525197,0.91486365],"study_design_scores_gemma":[0.000109041095,0.000094890915,0.00001946461,0.0022811107,0.00041196367,0.00003100206,0.0000022353513,0.0000012077442,0.0006630032,0.0000034660798,0.99556094,0.00082168693],"about_ca_topic_score_codex":0.000001587623,"about_ca_topic_score_gemma":0.000003976688,"teacher_disagreement_score":0.92030895,"about_ca_system_score_codex":0.00005704732,"about_ca_system_score_gemma":0.0000887074,"threshold_uncertainty_score":0.999505},"labels":[],"label_agreement":null},{"id":"W2971521058","doi":"10.3791/59780","title":"Pooled CRISPR-Based Genetic Screens in Mammalian Cells","year":2019,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Computational biology; Genome editing; Biology; Genome; Genetic screen; Context (archaeology); Cas9; Functional genomics; Genomics; Gene; Genetics; Phenotype","score_opus":0.011197284412041075,"score_gpt":0.39146166728462145,"score_spread":0.38026438287258035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971521058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98913807,0.0018759355,0.00811219,0.0000347957,0.00042626774,0.00015691169,0.0000028230295,0.0000037188488,0.0002492774],"genre_scores_gemma":[0.9929456,0.00006446824,0.00634475,0.00022426459,0.00014426121,0.0000039129427,0.000005672392,0.000030364847,0.00023668773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882215,0.000061165134,0.00045640243,0.00018157545,0.00022742542,0.00025127662],"domain_scores_gemma":[0.9994025,0.000009029499,0.00016533524,0.00023117245,0.000075729986,0.00011620398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001819424,0.00016320847,0.00025072487,0.00014198487,0.000016116966,0.000022136102,0.0002155914,0.00011170662,0.00014544434],"category_scores_gemma":[0.00001888184,0.00015497055,0.00014935543,0.00009574756,0.000018126295,0.00000459745,0.0000438484,0.00010823617,0.000023684079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021860977,0.000137474,0.0045325416,0.000016782418,0.00004149672,0.000020837879,0.000067028144,0.0027547241,0.9913128,0.0000031519016,0.00056887936,0.00032564413],"study_design_scores_gemma":[0.0031395522,0.0005614284,0.0063773594,0.00004730974,0.000016325803,0.000017843433,0.00014251606,0.00042362345,0.98229307,0.0000052219125,0.0067961137,0.00017962736],"about_ca_topic_score_codex":0.00001377516,"about_ca_topic_score_gemma":0.0000029560792,"teacher_disagreement_score":0.009019751,"about_ca_system_score_codex":0.000028405399,"about_ca_system_score_gemma":0.00007270505,"threshold_uncertainty_score":0.6319516},"labels":[],"label_agreement":null},{"id":"W2971621341","doi":"10.9787/kjbs.2019.51.3.175","title":"Gene-Edited Crops: Present Status and their Future","year":2019,"lang":"en","type":"article","venue":"Korean Journal of Breeding Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Rural Development Administration; Canadian Food Inspection Agency; U.S. Department of Agriculture","keywords":"Commercialization; Harmonization; Biotechnology; Gene technology; Emerging technologies; Genome editing; Biology; Genetic engineering; Standardization; Plant breeding; Risk analysis (engineering); Business; Computer science; Gene; Marketing; Genome; Agronomy; Genetics","score_opus":0.0062902728112906444,"score_gpt":0.2628913383676465,"score_spread":0.25660106555635587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971621341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955392,0.0016885247,0.0015507055,0.00016050178,0.00069154805,0.000044981767,0.0000029349621,0.0000028388156,0.000318799],"genre_scores_gemma":[0.9974889,0.00031218995,0.0012348265,0.00003749179,0.0008503127,2.5825014e-7,9.805054e-7,0.0000072129164,0.00006783334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926686,0.00000779656,0.00015722032,0.00015824044,0.00018046937,0.00022943059],"domain_scores_gemma":[0.99945784,0.000007660342,0.00008884106,0.00013697358,0.0001548186,0.00015386514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003869238,0.0000870997,0.00010128658,0.00008802841,0.00005896345,0.00005614141,0.00023064145,0.00003765085,0.000006599438],"category_scores_gemma":[0.000042019954,0.000063605374,0.000042197236,0.00014898276,0.00012438312,0.000012819731,0.00009091174,0.00009205376,9.672809e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015691181,0.000007777441,0.009894134,0.000007529084,0.000010729202,0.0000016799493,0.00024099354,0.00048448032,0.9831123,0.00001792035,0.00026840332,0.0059383963],"study_design_scores_gemma":[0.0005624495,0.0006388783,0.04817247,0.000039396276,0.000008898673,0.00033931268,0.0010210173,0.00082855875,0.93582714,0.000051181578,0.012337254,0.00017346104],"about_ca_topic_score_codex":0.0000027634253,"about_ca_topic_score_gemma":9.942084e-7,"teacher_disagreement_score":0.047285143,"about_ca_system_score_codex":0.000011722169,"about_ca_system_score_gemma":0.00008572747,"threshold_uncertainty_score":0.25937518},"labels":[],"label_agreement":null},{"id":"W2971826972","doi":"10.1016/j.crbiot.2019.08.001","title":"Risk and safety considerations of genome edited crops: Expert opinion","year":2019,"lang":"en","type":"article","venue":"Current Research in Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canada First Research Excellence Fund","keywords":"Surprise; Genome editing; Emerging technologies; Expert opinion; Scientific evidence; Biotechnology; Agriculture; Politics; Human health; Risk analysis (engineering); Business; Genome; Political science; Biology; Computer science; Medicine; Sociology; Environmental health; Genetics; Law; Ecology","score_opus":0.03493736127541586,"score_gpt":0.39890159872028136,"score_spread":0.3639642374448655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971826972","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705928,0.024289893,0.0033255145,0.0006260957,0.00041559833,0.0004540649,0.000037755133,0.000018313965,0.00023997518],"genre_scores_gemma":[0.9736628,0.025650805,0.0005043035,0.0000061219985,0.00008625796,0.00001894687,0.000042919935,0.000009323469,0.000018499837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990752,0.000075413416,0.00019024365,0.00029017378,0.00010860468,0.00026040166],"domain_scores_gemma":[0.9994737,0.000044248613,0.000030004307,0.00033662753,0.00007541228,0.0000400359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039757093,0.00008206033,0.00012611,0.00026110385,0.000041520438,0.000007672069,0.00011733742,0.0002316167,0.00003316344],"category_scores_gemma":[0.00020177134,0.00008037469,0.000024001403,0.00019712574,0.00022276238,0.000002243089,0.00023836072,0.00033262168,0.000009103998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045533183,0.00007352616,0.006211587,0.00006103723,0.000016706443,9.253111e-7,0.00006188719,0.0002051803,0.97475934,0.0017169097,0.00050866656,0.016338691],"study_design_scores_gemma":[0.0016415959,0.00078427163,0.022425259,0.00010641886,0.0000026446744,0.000029139486,0.00031851808,0.0010925379,0.60938823,0.0014298727,0.36246085,0.00032067738],"about_ca_topic_score_codex":0.000033093926,"about_ca_topic_score_gemma":0.000018859897,"teacher_disagreement_score":0.36537114,"about_ca_system_score_codex":0.00001403176,"about_ca_system_score_gemma":0.000047838803,"threshold_uncertainty_score":0.32775846},"labels":[],"label_agreement":null},{"id":"W2971842044","doi":"10.1021/acssynbio.9b00232","title":"A Broad-Host-Range CRISPRi Toolkit for Silencing Gene Expression in <i>Burkholderia</i>","year":2019,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cystic Fibrosis Canada; Institut national de la recherche scientifique; Cystic Fibrosis Foundation","keywords":"Gene silencing; Host (biology); Biology; Computational biology; Genetics; Gene expression; Burkholderia; Range (aeronautics); Gene; Burkholderia pseudomallei; Expression (computer science); Computer science; Bacteria; Engineering; Programming language","score_opus":0.008717419336382651,"score_gpt":0.2927382615832976,"score_spread":0.28402084224691493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971842044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97728515,0.0021637422,0.018818669,0.00014408791,0.000521131,0.00052679016,0.000033438275,0.00002278642,0.00048418107],"genre_scores_gemma":[0.99523556,0.00026020134,0.0035609032,0.00025555445,0.00018862938,0.00011399715,0.000060314025,0.000038891223,0.0002859501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986275,0.000051106006,0.00028181795,0.00054405804,0.000056998335,0.00043856294],"domain_scores_gemma":[0.99928254,0.000059518476,0.0000603032,0.0004896251,0.000043921977,0.0000640989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021544723,0.00021192632,0.00026030783,0.00007399681,0.000037891074,0.000012704519,0.00025659127,0.0003204463,0.000043796303],"category_scores_gemma":[0.000112854716,0.00019711797,0.00009926382,0.00007320622,0.00004702913,0.000003785133,0.00013862856,0.000102950115,0.000028879047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071962095,0.000034231718,0.004143051,0.000037282844,0.000013580061,0.0000010090783,0.000072514995,0.0001617594,0.9936501,0.00005411194,0.00022047701,0.0015399193],"study_design_scores_gemma":[0.000848197,0.0003102881,0.0014780487,0.000038914543,0.000010707521,0.000018442031,0.00008245911,0.00013673196,0.9779968,0.000105327235,0.018696977,0.00027709012],"about_ca_topic_score_codex":0.000023957486,"about_ca_topic_score_gemma":0.000018207062,"teacher_disagreement_score":0.018476501,"about_ca_system_score_codex":0.000016939108,"about_ca_system_score_gemma":0.000030610558,"threshold_uncertainty_score":0.80382377},"labels":[],"label_agreement":null},{"id":"W2972407461","doi":"10.1007/978-1-4939-9837-1_7","title":"Generation of Large Fragment Knock-In Mouse Models by Microinjecting into 2-Cell Stage Embryos","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Gene knockin; CRISPR; Germline; Biology; Mutant; Homologous recombination; Computational biology; Fragment (logic); Genetics; Embryo; Genome editing; Cell biology; Gene; Computer science; Algorithm","score_opus":0.015428192358722325,"score_gpt":0.38777653180374955,"score_spread":0.3723483394450272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972407461","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49888578,0.0017023376,0.49897128,0.000009609489,0.00008209872,0.0001655154,0.000011470252,0.0000037740326,0.00016814389],"genre_scores_gemma":[0.5915317,0.00015752489,0.40724316,0.0001278995,0.000027127977,0.000029600227,0.00014600385,0.00003354771,0.00070343306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835575,0.00039919617,0.00039225348,0.00046599182,0.000058565118,0.00032827668],"domain_scores_gemma":[0.99941725,0.000024395566,0.00009029515,0.0003920611,0.000035635494,0.000040371844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084005797,0.00018633323,0.00027810995,0.00012538489,0.000015802218,0.0000060951174,0.00018939469,0.00027674175,0.000019226489],"category_scores_gemma":[0.00006119045,0.0001994002,0.00008292681,0.00012766568,0.000026269965,0.0000030136491,0.0001577589,0.00015499594,0.0000020351515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018850918,0.00008337131,0.0018427116,0.000048466416,0.00001486611,0.0000016207682,0.00010510421,0.01673625,0.97991884,0.00016253148,0.000026345162,0.0010410532],"study_design_scores_gemma":[0.0008147273,0.00019033584,0.00001734833,0.000007824193,0.0000042863107,0.00000135987,0.00010831799,0.015586227,0.9815913,0.0001220886,0.0013539393,0.00020224176],"about_ca_topic_score_codex":0.00009995147,"about_ca_topic_score_gemma":0.000050182123,"teacher_disagreement_score":0.092645936,"about_ca_system_score_codex":0.000028466948,"about_ca_system_score_gemma":0.000033976812,"threshold_uncertainty_score":0.81313044},"labels":[],"label_agreement":null},{"id":"W2972469055","doi":"10.1038/s41576-019-0178-3","title":"Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022","year":2019,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Computational biology; Genome; Genetics; Gene","score_opus":0.03488637561991457,"score_gpt":0.4062784313704898,"score_spread":0.3713920557505752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972469055","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000266186,0.9914571,0.0025377146,0.00002233323,0.0030329388,0.0016782369,0.00010940591,0.00003156442,0.0011040876],"genre_scores_gemma":[0.000046867437,0.9890584,0.000839057,0.00037348093,0.0015514285,0.00008148224,0.0015863522,0.00020417209,0.0062587713],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967855,0.00038874193,0.00094218244,0.0010864652,0.00028792096,0.0005091791],"domain_scores_gemma":[0.9979634,0.00002175664,0.00040445547,0.0012645838,0.0001007614,0.0002450039],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005329101,0.0008490226,0.001514444,0.00021150407,0.00015242759,0.00016304162,0.0011996846,0.00087386055,0.000093320705],"category_scores_gemma":[0.00011392897,0.0007335203,0.00067627744,0.000472343,0.000030921037,0.000004312884,0.000698551,0.0010996915,0.000114366696],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000015245147,0.000011071644,0.00001005622,0.003909324,0.000084348125,0.0000021518201,0.000015824799,0.00007219267,0.0011677619,0.0000010757716,0.207612,0.78711265],"study_design_scores_gemma":[0.00009521315,0.00011966152,0.000025415091,0.0023254412,0.00043696817,0.00005641584,0.000003378776,0.000004199561,0.0006549026,0.0000020788948,0.9954711,0.0008052172],"about_ca_topic_score_codex":0.0000020507873,"about_ca_topic_score_gemma":0.0000066103685,"teacher_disagreement_score":0.78785914,"about_ca_system_score_codex":0.000072786715,"about_ca_system_score_gemma":0.00010061653,"threshold_uncertainty_score":0.9995116},"labels":[],"label_agreement":null},{"id":"W2972584372","doi":"10.1007/978-1-4939-9837-1_5","title":"Targeted Mutations in the Mouse via Embryonic Stem Cells","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Toronto Centre for Phenogenomics","funders":"","keywords":"Embryonic stem cell; Homologous recombination; Gene targeting; CRISPR; Biology; Transfection; Cas9; Mutant; Gene; Stem cell; Genetics; Cell biology; Genome editing; Molecular biology","score_opus":0.010301279744532443,"score_gpt":0.3723419286719466,"score_spread":0.36204064892741417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972584372","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4201982,0.0010306531,0.5780052,0.00008220449,0.00015273113,0.00026148173,0.000004638835,0.0000069219195,0.00025797868],"genre_scores_gemma":[0.7358627,0.000087943146,0.26271975,0.00062660273,0.00004781157,0.000091926326,0.000089463785,0.000037500973,0.00043631214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983043,0.0007251453,0.000233714,0.00036820283,0.00005429905,0.00031435466],"domain_scores_gemma":[0.9993552,0.0000635269,0.000043515367,0.0004848202,0.000023010274,0.000029913846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008577246,0.00015963774,0.00018612866,0.000107701504,0.000019181862,0.000009973834,0.0003271247,0.00021652726,0.000020111316],"category_scores_gemma":[0.00003984676,0.000132092,0.00008434558,0.00022849714,0.000050629187,0.00000146287,0.00008849315,0.000194859,0.000016144839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001092781,0.000029948087,0.0012690789,0.000010429975,0.0000150594815,0.0000054530633,0.00009088974,0.003933551,0.9908812,0.00020076624,0.000022698703,0.0035300215],"study_design_scores_gemma":[0.00044183654,0.00015185497,0.00051358383,0.0000035324865,0.0000070096075,0.000011759344,0.00015017022,0.0010724141,0.9904258,0.00035291284,0.006686913,0.00018221281],"about_ca_topic_score_codex":0.000024035506,"about_ca_topic_score_gemma":0.000029819303,"teacher_disagreement_score":0.31566447,"about_ca_system_score_codex":0.000014767699,"about_ca_system_score_gemma":0.000029912822,"threshold_uncertainty_score":0.5386555},"labels":[],"label_agreement":null},{"id":"W2972647388","doi":"10.1145/3307339.3342623","title":"Beta-Binomial Modeling of CRISPR Pooled Screen Data Identifies Target Genes with Greater Sensitivity and fewer False Negatives","year":2019,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Houston Endowment; Howard Hughes Medical Institute","keywords":"CRISPR; Negative binomial distribution; Computer science; Cas9; Beta-binomial distribution; Computational biology; Count data; Binomial distribution; Identification (biology); Data mining; Gene; Biology; Genetics; Statistics; Mathematics","score_opus":0.015928303736804334,"score_gpt":0.2745402959310548,"score_spread":0.25861199219425046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972647388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9192117,0.00059677276,0.079623446,0.000046122183,0.000046965994,0.00014217981,0.00006928519,0.00000927312,0.00025430127],"genre_scores_gemma":[0.99349016,0.00006118798,0.005796725,0.00003164779,0.0000712955,0.0000018376653,0.00015560354,0.000017976035,0.00037353864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992004,0.000028539751,0.00014728468,0.00037293753,0.00009349811,0.00015733883],"domain_scores_gemma":[0.99933964,0.000009187441,0.00003399449,0.0005010395,0.00006897497,0.000047170728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159221,0.00014421837,0.00018695767,0.000032236872,0.000028018203,0.00002503674,0.00011182371,0.00006139946,0.000020987953],"category_scores_gemma":[0.000011675324,0.00011238524,0.000028330864,0.00003268558,0.00004825331,0.000011494146,0.00027158187,0.00004458797,0.0000025991578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013088658,0.000019517609,0.023423811,0.000051652343,0.00017801991,0.000003272222,0.00007173875,0.01714077,0.9584178,0.000016527132,0.0001383172,0.00040769886],"study_design_scores_gemma":[0.00062876113,0.000120506054,0.0052392096,0.000018408355,0.000057158755,0.000016959275,0.0002667899,0.067752704,0.9254193,0.000010939886,0.0002335252,0.0002357458],"about_ca_topic_score_codex":0.00015311665,"about_ca_topic_score_gemma":0.00014485123,"teacher_disagreement_score":0.07427853,"about_ca_system_score_codex":0.0000019838303,"about_ca_system_score_gemma":0.000020346408,"threshold_uncertainty_score":0.4582937},"labels":[],"label_agreement":null},{"id":"W2972929791","doi":"10.7554/elife.48417","title":"Long-term adult human brain slice cultures as a model system to study human CNS circuitry and disease","year":2019,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Rural Affairs; Eberhard Karls Universität Tübingen; Deutsche Forschungsgemeinschaft","keywords":"Neuroscience; Cytoarchitecture; Human brain; Biocytin; Biology; Slice preparation; Model organism; Human disease; Electrophysiology; Computational biology; Gene; Genetics","score_opus":0.007297473699041463,"score_gpt":0.3149562249775188,"score_spread":0.3076587512784773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972929791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974534,0.00033481093,0.0010485015,0.00006660023,0.00006121362,0.0004910723,0.000014734408,0.000033221208,0.0004964789],"genre_scores_gemma":[0.9978151,0.0000055953055,0.000039179307,0.00052276783,0.00017071186,0.000043040047,0.000045103785,0.000027966826,0.0013305844],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99907047,0.000024699162,0.00015761411,0.00039081436,0.00015483568,0.00020155532],"domain_scores_gemma":[0.9992329,0.0000034902455,0.000027808093,0.00039947624,0.00005965921,0.00027669792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083640654,0.0001644434,0.00014027725,0.00003227386,0.00009756541,0.000040070132,0.00015563666,0.00006525487,0.000007979501],"category_scores_gemma":[0.000033856737,0.00015775014,0.00005021132,0.00004061988,0.000012691841,0.0000026472046,0.00013413647,0.000066044195,0.000023077642],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029296292,0.00013468588,0.06427449,0.00015774918,0.00008082613,0.000016075708,0.0007123373,0.0021021462,0.9309854,0.0003301381,0.0010191374,0.00015770986],"study_design_scores_gemma":[0.0051971264,0.0020202918,0.83109283,0.0003222898,0.0002498891,0.000052621323,0.003189766,0.0027690777,0.15214857,0.000045934485,0.0009807897,0.0019307876],"about_ca_topic_score_codex":0.000022314209,"about_ca_topic_score_gemma":0.00004276336,"teacher_disagreement_score":0.77883685,"about_ca_system_score_codex":0.0000112421885,"about_ca_system_score_gemma":0.000022083519,"threshold_uncertainty_score":0.64328635},"labels":[],"label_agreement":null},{"id":"W2973379642","doi":"10.1186/s40694-019-0076-7","title":"Efficient marker free CRISPR/Cas9 genome editing for functional analysis of gene families in filamentous fungi","year":2019,"lang":"en","type":"article","venue":"Fungal Biology and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Danmarks Tekniske Universitet; Concordia University","keywords":"CRISPR; Genome editing; Gene knockout; Cas9; Biology; Plasmid; Genetics; Gene; Transformation (genetics); Computational biology; Marker gene; Genome","score_opus":0.004916068669664316,"score_gpt":0.24648045743813385,"score_spread":0.24156438876846953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2973379642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9763163,0.0032082347,0.01949796,0.00012754231,0.00025496242,0.00024182658,0.0002425589,0.000017874896,0.000092776114],"genre_scores_gemma":[0.99750346,0.0002474054,0.0016556032,0.00006733631,0.000086505504,0.000029524752,0.00030497336,0.000010739654,0.000094475334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989144,0.000026240838,0.00027532948,0.00043783346,0.000044016695,0.00030213228],"domain_scores_gemma":[0.9994642,0.000044854598,0.00007947984,0.00033446448,0.000046529192,0.000030431549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021673508,0.00016074766,0.00032174346,0.00039718673,0.000036239253,0.0000038647454,0.00016581726,0.0005507698,0.000033377837],"category_scores_gemma":[0.000073227864,0.00014956569,0.00011818674,0.00030528542,0.00013830997,0.000001162729,0.00015590785,0.0001230634,0.0000019989848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012208101,0.00003916754,0.040206637,0.000026217262,0.000332514,9.305382e-7,0.000015947151,0.0035634208,0.9538723,0.0005089077,0.00004373168,0.0012681135],"study_design_scores_gemma":[0.0016699409,0.0010269532,0.1756912,0.000011031886,0.00028275803,0.000025572377,0.0003415752,0.010379917,0.8029757,0.00012281022,0.0070638456,0.00040865623],"about_ca_topic_score_codex":0.00001845365,"about_ca_topic_score_gemma":0.000066022614,"teacher_disagreement_score":0.1508966,"about_ca_system_score_codex":0.000010385369,"about_ca_system_score_gemma":0.000019184858,"threshold_uncertainty_score":0.6099112},"labels":[],"label_agreement":null},{"id":"W2974023053","doi":"10.1128/aem.01644-19","title":"Using the Endogenous CRISPR-Cas System of <i>Heliobacterium modesticaldum</i> To Delete the Photochemical Reaction Center Core Subunit Gene","year":2019,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Basic Energy Sciences; U.S. Department of Energy","keywords":"CRISPR; Homologous recombination; Biology; Genetics; Plasmid; Gene; Site-specific recombination; Locus (genetics); In silico; Genome; Computational biology; Recombination; Recombinase","score_opus":0.012265012264838768,"score_gpt":0.2292271934884061,"score_spread":0.2169621812235673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974023053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99666005,0.00022237505,0.0023773143,0.000020590687,0.00009557367,0.00040423495,0.00009173669,0.000005364334,0.00012275354],"genre_scores_gemma":[0.99908257,0.00006481679,0.00033681295,0.00023948147,0.00006384407,0.00002061321,0.00015669322,0.00001831458,0.000016856211],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931425,0.00001833078,0.00016778916,0.00025585943,0.000032233038,0.00021154784],"domain_scores_gemma":[0.99960846,0.000014854601,0.00004478492,0.0002840815,0.0000042047227,0.000043591284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000074860196,0.00014341382,0.00014119585,0.000014428982,0.00005956779,0.0000058083883,0.00013678723,0.00011409676,0.0000071393883],"category_scores_gemma":[0.0000017692431,0.00009597546,0.000044854565,0.000027254351,0.000114691684,0.0000012027871,0.00017351855,0.00008684318,0.000011587157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006577757,0.000023072444,0.0011045359,0.000017449871,0.000034031662,5.756986e-7,0.000064226595,0.00021116603,0.99832463,0.00001613338,0.000024243465,0.00011417397],"study_design_scores_gemma":[0.0003142217,0.000091848466,0.00084544567,0.000006250114,0.00002890624,0.00043099088,0.00030000517,0.00012109016,0.9952741,0.0000025759107,0.0024617068,0.00012284207],"about_ca_topic_score_codex":0.000016681177,"about_ca_topic_score_gemma":0.0000015852124,"teacher_disagreement_score":0.0030504966,"about_ca_system_score_codex":0.00002396141,"about_ca_system_score_gemma":0.000006104283,"threshold_uncertainty_score":0.39137658},"labels":[],"label_agreement":null},{"id":"W2974223043","doi":"10.1038/s41551-019-0454-8","title":"High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting","year":2019,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Cell sorting; Genetic screen; CRISPR; Phenotype; Computational biology; High-throughput screening; Biology; Cas9; Cell; Genome; Sorting; Cell biology; Genetics; Gene; Computer science","score_opus":0.0017522620287305348,"score_gpt":0.21766039054399167,"score_spread":0.21590812851526114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974223043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7081809,0.0075382846,0.28229868,0.00011293559,0.001206157,0.00025460872,0.00000926364,0.000111020214,0.00028814632],"genre_scores_gemma":[0.9730506,0.00007098709,0.025427455,0.00021113429,0.00057476386,0.000013426796,0.00020344896,0.00007776063,0.00037042107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982352,0.000013928483,0.0003522217,0.00051814254,0.00031007576,0.00057039794],"domain_scores_gemma":[0.99918,0.000037633105,0.00006570742,0.00046667084,0.000048740705,0.00020120811],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000208569,0.00031540435,0.0002692943,0.0001216224,0.000051211373,0.00003221704,0.0003463785,0.0005926399,0.000114793416],"category_scores_gemma":[0.00011385229,0.00031926978,0.00013725786,0.00024816458,0.000035235495,0.0000072354774,0.00020224061,0.0006289931,0.000053369316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002043012,0.000033380275,0.00049871503,0.0001321383,0.000054058175,0.000008888146,0.000031592455,0.018314712,0.9780833,0.000027099257,0.00018118026,0.0026144856],"study_design_scores_gemma":[0.0051619746,0.001354131,0.054144725,0.000262924,0.00015123135,0.00011996088,0.00013552886,0.05948914,0.5704918,0.00006139238,0.30579185,0.0028353538],"about_ca_topic_score_codex":0.000011102385,"about_ca_topic_score_gemma":9.275182e-7,"teacher_disagreement_score":0.40759152,"about_ca_system_score_codex":0.000027332744,"about_ca_system_score_gemma":0.000034658435,"threshold_uncertainty_score":0.9999259},"labels":[],"label_agreement":null},{"id":"W2974281126","doi":"10.1007/978-1-4939-9865-4_14","title":"Emerging Genome Engineering Tools in Crop Research and Breeding","year":2019,"lang":"en","type":"book-chapter","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge; Agriculture and Agri-Food Canada","funders":"","keywords":"Genome editing; Transcription activator-like effector nuclease; Biology; CRISPR; Zinc finger nuclease; Genome engineering; Genome; Epigenome; Biotechnology; Computational biology; Cas9; Genetics; Gene; DNA methylation; Gene expression","score_opus":0.04870684557916598,"score_gpt":0.44724307358131377,"score_spread":0.3985362280021478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974281126","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019892108,0.04095118,0.8791666,0.00014737957,0.0007869975,0.001155167,0.00004388987,0.000036829726,0.057819832],"genre_scores_gemma":[0.029974975,0.0064580953,0.90463704,0.0002729854,0.00086190057,0.0001474398,0.0005305341,0.0005882844,0.05652874],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978156,0.00015069263,0.00045604352,0.0008597557,0.00011601742,0.000601871],"domain_scores_gemma":[0.99912673,0.0001251263,0.000064725034,0.00052949064,0.000072483715,0.00008145164],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018694898,0.00037545024,0.00051416294,0.0006305181,0.000028066932,0.00003112414,0.0003243304,0.0008631715,0.000028516077],"category_scores_gemma":[0.00032660135,0.00042581072,0.000095421485,0.00010492631,0.000119065444,0.00000279565,0.0005666718,0.00081083825,0.000006219598],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019539866,0.000007801264,0.00016735011,0.00009190476,0.00004654184,0.000038141243,0.00003999433,0.0014514604,0.9803024,0.008424511,0.000007916689,0.009402442],"study_design_scores_gemma":[0.0022965183,0.0017659563,0.0012876238,0.0006758658,0.000056330893,0.00019962636,0.00009127003,0.0023225155,0.37021032,0.0125188865,0.60571337,0.002861741],"about_ca_topic_score_codex":0.000017345099,"about_ca_topic_score_gemma":0.000018697905,"teacher_disagreement_score":0.6100921,"about_ca_system_score_codex":0.000059606562,"about_ca_system_score_gemma":0.00007033485,"threshold_uncertainty_score":0.9998194},"labels":[],"label_agreement":null},{"id":"W2974728347","doi":"10.1007/978-1-4939-9865-4_15","title":"CRISPR/Cas9-Mediated Targeted Mutagenesis in Wheat Doubled Haploids","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Saskatchewan Research Council (Canada)","funders":"","keywords":"Genome editing; Microspore; CRISPR; Doubled haploidy; Ploidy; Biology; Cas9; Mutagenesis; Genetics; Genome; Gene; Mutant; Computational biology; Botany; Stamen","score_opus":0.010014425322039399,"score_gpt":0.39315852753502334,"score_spread":0.38314410221298395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974728347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56863415,0.0026872228,0.42690694,0.0001059183,0.00042786522,0.00037133088,0.000009204295,0.000024088093,0.0008332878],"genre_scores_gemma":[0.6852599,0.0002640036,0.31317088,0.0005084021,0.000073962765,0.00009874112,0.00021793756,0.00007255198,0.00033365193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975056,0.00063323084,0.0004589174,0.00072907883,0.00008304994,0.0005901067],"domain_scores_gemma":[0.9990985,0.000074260366,0.00006381045,0.00062134454,0.00004817323,0.00009394313],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009583616,0.00030746835,0.00043797152,0.0002894399,0.00001960628,0.000013263531,0.00034456482,0.00050867395,0.00010743593],"category_scores_gemma":[0.0003132302,0.0003139476,0.00013595898,0.00041242843,0.00006865457,0.0000030544452,0.00020632442,0.00024942003,0.000032406784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007843749,0.00005247195,0.02009842,0.000026125546,0.000035568344,0.000022693055,0.000043364897,0.0015519995,0.9746896,0.00012250459,0.000032831034,0.0032459544],"study_design_scores_gemma":[0.0016518984,0.00027219867,0.0059766886,0.000017162776,0.0000115099465,0.000016773245,0.00006162155,0.0011918801,0.9795983,0.00029559428,0.01047683,0.00042953342],"about_ca_topic_score_codex":0.000097744116,"about_ca_topic_score_gemma":0.00007520194,"teacher_disagreement_score":0.116625726,"about_ca_system_score_codex":0.00003684996,"about_ca_system_score_gemma":0.00006915289,"threshold_uncertainty_score":0.9999313},"labels":[],"label_agreement":null},{"id":"W2975014278","doi":"","title":"RNA-mediated Post-transcriptional Gene Silencing","year":2004,"lang":"en","type":"article","venue":"分子植物育种","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"RNA silencing; Gene silencing; Gene; RNA-induced silencing complex; RNA; Biology; RNA interference; RNA-induced transcriptional silencing; Genetics; Regulation of gene expression; Function (biology); Trans-acting siRNA; Computational biology","score_opus":0.004932188012409007,"score_gpt":0.2505483162490104,"score_spread":0.24561612823660142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2975014278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9674342,0.0014538309,0.029325053,0.00020560816,0.0002512324,0.000068768444,0.000025051264,0.000027347578,0.0012088614],"genre_scores_gemma":[0.99697804,0.00008779117,0.0019391512,0.0002833708,0.00033079984,0.000007956459,0.00020502273,0.000018098719,0.00014974119],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940276,0.0000079373085,0.00011264321,0.00019337141,0.00009545446,0.00018780238],"domain_scores_gemma":[0.9996968,0.000003286717,0.000016161466,0.00016312748,0.00004823891,0.000072384886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064905806,0.00010166553,0.000068544425,0.000028357174,0.00004342001,0.000014494536,0.000095881456,0.00008588996,0.000033914635],"category_scores_gemma":[0.000029354946,0.00010450227,0.00006344218,0.00005259697,0.000022593,0.0000025084285,0.000025436217,0.000059569196,0.000043294633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000075969856,0.000020622912,0.00008990469,0.0000065270283,0.000017782086,0.000004327363,0.00005801537,0.0031462794,0.99590176,0.00007064913,0.00008925507,0.0005872529],"study_design_scores_gemma":[0.0005710028,0.00010601259,0.009721227,0.000008399219,0.000009108075,0.000026554939,0.000059910784,0.000020724152,0.984551,0.000072035575,0.004687196,0.00016683711],"about_ca_topic_score_codex":0.000034022258,"about_ca_topic_score_gemma":0.000024754096,"teacher_disagreement_score":0.02954382,"about_ca_system_score_codex":0.000013210033,"about_ca_system_score_gemma":0.000053029526,"threshold_uncertainty_score":0.4261479},"labels":[],"label_agreement":null},{"id":"W2975604509","doi":"10.1101/787200","title":"<i>Listeria</i> phages induce Cas9 degradation to protect lysogenic genomes","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University of California, San Francisco; Margaret Q. Landenberger Research Foundation; Vallee Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Canadian Institutes of Health Research; Sandler Foundation; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Lytic cycle; Cas9; Listeria; Biology; Lysogenic cycle; Prophage; Bacteriophage; CRISPR interference; Genetics; Listeria monocytogenes; Gene; Bacteria; Virus; Escherichia coli","score_opus":0.011322493587391033,"score_gpt":0.2507193634426579,"score_spread":0.23939686985526684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2975604509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9751987,0.0036814928,0.017935228,0.00014002949,0.001281874,0.0014137998,0.00020806998,0.00012213731,0.000018664537],"genre_scores_gemma":[0.99271905,0.00034694996,0.0052989516,0.00027262067,0.00079048215,0.0003440683,0.0000043996583,0.00016267003,0.00006079303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99754286,0.00007842717,0.00042644452,0.0011459002,0.00026484855,0.00054149784],"domain_scores_gemma":[0.99776685,0.000010977063,0.00019305403,0.0015108372,0.0002662338,0.00025202188],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003415631,0.0005708685,0.00043050427,0.000178336,0.00008985915,0.00016340506,0.0005907572,0.00061483117,0.000020997453],"category_scores_gemma":[0.00011904143,0.0006408948,0.0001816451,0.00024097436,0.000036342994,0.000007509616,0.0007441741,0.00037997865,0.000098364544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003203068,0.000040818246,0.0010125325,0.00025461946,0.00013169218,0.000008070748,0.0000072412668,0.0013968494,0.99654394,0.000010266613,0.0005482819,0.000013667491],"study_design_scores_gemma":[0.00032572294,0.00012749467,0.011423104,0.00011403245,0.00007186454,6.5647484e-8,0.0000029292135,0.000095610434,0.95680064,2.8903924e-7,0.030254964,0.00078328064],"about_ca_topic_score_codex":0.000031505762,"about_ca_topic_score_gemma":0.0000059379786,"teacher_disagreement_score":0.039743286,"about_ca_system_score_codex":0.00009994521,"about_ca_system_score_gemma":0.0003748657,"threshold_uncertainty_score":0.9996042},"labels":[],"label_agreement":null},{"id":"W2976311530","doi":"10.1016/j.devcel.2019.09.004","title":"Defend Thyself and Thy Offspring","year":2019,"lang":"en","type":"letter","venue":"Developmental Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Offspring; Cell biology; Genetics; Zoology; Pregnancy","score_opus":0.006073348047392094,"score_gpt":0.22724941668990906,"score_spread":0.22117606864251696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2976311530","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7125346,0.022497833,0.004462633,0.05154326,0.004392121,0.0021062025,0.00025390665,0.00019195565,0.2020175],"genre_scores_gemma":[0.30000344,0.0026020114,0.026414383,0.5621026,0.005987946,0.000102804224,0.0046717306,0.0005137242,0.097601354],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989746,0.000013165232,0.00016186897,0.00043027048,0.00012722434,0.00029282717],"domain_scores_gemma":[0.99970335,0.0000099173585,0.000044228564,0.00019090335,0.00001690886,0.00003470404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005309156,0.00026531567,0.00017438697,0.000048994512,0.00004201468,0.00003282106,0.00015931512,0.0004301056,0.000035195462],"category_scores_gemma":[0.0000057495135,0.00027418105,0.000058932736,0.00003320397,0.000026518272,0.0000014703718,0.00022900909,0.00033746418,0.00008265004],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000067048713,0.000008862295,0.00084853865,0.00027279803,0.00006095255,0.000036256224,0.00008262641,0.000011787392,0.15240194,0.0000010018533,0.8453216,0.0009469325],"study_design_scores_gemma":[0.00021347188,0.000031095853,0.00039309217,0.000018132641,0.000013125599,0.00003624302,0.000026155154,0.0000050592907,0.15807204,0.0000034052914,0.840846,0.00034217475],"about_ca_topic_score_codex":0.000006281033,"about_ca_topic_score_gemma":0.0000040279,"teacher_disagreement_score":0.5105593,"about_ca_system_score_codex":0.000019435094,"about_ca_system_score_gemma":0.00008271207,"threshold_uncertainty_score":0.99997103},"labels":[],"label_agreement":null},{"id":"W2976820714","doi":"10.1038/s41598-019-50302-0","title":"Whole Genome Sequencing of the Mutamouse Model Reveals Strain- and Colony-Level Variation, and Genomic Features of the Transgene Integration Site","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Environment and Climate Change Canada; Health Canada","funders":"Health Canada","keywords":"Biology; Genome; Genetics; Copy-number variation; Whole genome sequencing; Comparative genomic hybridization; Structural variation; Retrotransposon; DNA sequencing; Reference genome; Computational biology; Context (archaeology); Genomics; Gene; Transposable element","score_opus":0.009439140312302908,"score_gpt":0.2397198076634092,"score_spread":0.23028066735110628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2976820714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957433,0.00042493682,0.003079471,0.000048111775,0.0003373488,0.00026267153,0.000040272873,0.0000021616581,0.00006172806],"genre_scores_gemma":[0.9973633,0.000011738372,0.00068234367,0.000015108731,0.0000131900315,0.0000030822177,0.000024854853,0.000007043496,0.0018792843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992986,0.000021177057,0.00022038522,0.00025280233,0.00011922227,0.00008786765],"domain_scores_gemma":[0.9993337,0.0000045684296,0.00014228867,0.00041795222,0.00007908284,0.000022457538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041241397,0.00007214097,0.000091190224,0.000022850594,0.00006997331,0.000025667272,0.00007671112,0.00005739561,0.0000019251927],"category_scores_gemma":[0.000037384765,0.00004735468,0.0000442126,0.00008060518,0.00010033949,0.0000042025745,0.00006082089,0.000045213124,8.976813e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000030114686,0.000005474828,0.0012187966,0.000028416629,0.000009399464,2.469805e-7,0.0009051446,0.009509328,0.9881047,0.000019155332,0.00004180615,0.0001545072],"study_design_scores_gemma":[0.00013899128,0.00003118016,0.18127465,0.000027666007,0.00002903967,0.00006112195,0.000108073364,0.0022360526,0.8149919,0.0006911281,0.00031380693,0.00009643248],"about_ca_topic_score_codex":0.000015044052,"about_ca_topic_score_gemma":0.0000533013,"teacher_disagreement_score":0.18005584,"about_ca_system_score_codex":0.000009355657,"about_ca_system_score_gemma":0.000083136336,"threshold_uncertainty_score":0.19310677},"labels":[],"label_agreement":null},{"id":"W2977380244","doi":"10.1017/erm.2019.5","title":"Recent advancements in exon-skipping therapies using antisense oligonucleotides and genome editing for the treatment of various muscular dystrophies","year":2019,"lang":"en","type":"review","venue":"Expert Reviews in Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"","keywords":"Exon skipping; Exon; Muscular dystrophy; Duchenne muscular dystrophy; Genetics; Medicine; Antisense therapy; Biology; Bioinformatics; Alternative splicing; Gene; Oligonucleotide","score_opus":0.053136628350198827,"score_gpt":0.39956681563039703,"score_spread":0.3464301872801982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977380244","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008120187,0.98710316,0.0090666115,0.00004450274,0.00034444642,0.002605692,0.0000084175745,0.0000036007198,0.000011557171],"genre_scores_gemma":[0.00013316765,0.99511737,0.0038321388,0.00006704657,0.0003645875,0.00031578884,0.000089614616,0.00006616242,0.000014111265],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99785966,0.00017437707,0.00096753484,0.0005244869,0.0001446215,0.0003293217],"domain_scores_gemma":[0.99891,0.00007364055,0.000335835,0.0005890475,0.000044102468,0.00004734799],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049396564,0.0004853069,0.0017194513,0.00017698832,0.00004111543,0.0000093917015,0.00020294423,0.00016981679,0.000006673167],"category_scores_gemma":[0.00016973355,0.000305336,0.00027194485,0.00022188787,0.000113386865,0.0000035533808,0.00006715187,0.00010520116,4.518729e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010357059,0.00005846142,0.00000617735,0.004559429,0.00020053453,0.000017046503,0.00051045715,0.00017948767,0.035866193,0.000006177088,0.000010220894,0.9585755],"study_design_scores_gemma":[0.0007452632,0.00038547156,0.0000074453737,0.008814781,0.00025217433,0.00003283375,0.00015765807,0.000083631305,0.0005626979,0.0000032178416,0.9886926,0.00026226335],"about_ca_topic_score_codex":0.000040132607,"about_ca_topic_score_gemma":0.000015554248,"teacher_disagreement_score":0.9886823,"about_ca_system_score_codex":0.00007913921,"about_ca_system_score_gemma":0.000048409194,"threshold_uncertainty_score":0.99993986},"labels":[],"label_agreement":null},{"id":"W2978243962","doi":"10.1038/s41467-019-12448-3","title":"Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Ontario Genomics","keywords":"CRISPR; Plasmid; Bacterial conjugation; Salmonella enterica; Biology; Nuclease; Escherichia coli; Bacteria; Cas9; Computational biology; Genetics; Gene; Microbiology","score_opus":0.009990487301903928,"score_gpt":0.2995847502046647,"score_spread":0.28959426290276075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978243962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95673126,0.002888334,0.03772388,0.0005333422,0.0003561237,0.0005298263,0.0002274272,0.000015894024,0.0009939028],"genre_scores_gemma":[0.9955745,0.00010671618,0.0037146707,0.000051327712,0.000051885792,0.000027651533,0.00029069983,0.000016072365,0.0001665289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995198,0.000027839043,0.00015968045,0.00013598842,0.0000499747,0.00010669759],"domain_scores_gemma":[0.9990416,0.00005061598,0.000027977952,0.0006956718,0.00015264937,0.00003145775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000082493825,0.000088965186,0.00011638863,0.00003388586,0.00004843181,0.00000835976,0.0003625505,0.00015872787,0.000042499258],"category_scores_gemma":[0.00006407123,0.00008703509,0.00009866359,0.000062101724,0.000058947306,0.0000011724002,0.00009269396,0.00015473929,0.0000025826478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006780498,0.00006423431,0.00015078257,0.000021800439,0.0000476718,1.8255992e-8,0.00023131559,0.00059136027,0.9964818,0.001532814,0.00063691655,0.0001735301],"study_design_scores_gemma":[0.00088982104,0.00018941177,0.0015112325,0.00003345652,0.00003133692,0.0000014097377,0.0003623595,0.004411943,0.7971909,0.000016947766,0.19517507,0.00018614408],"about_ca_topic_score_codex":0.000002564284,"about_ca_topic_score_gemma":0.000026902873,"teacher_disagreement_score":0.19929087,"about_ca_system_score_codex":0.000008107081,"about_ca_system_score_gemma":0.000026118487,"threshold_uncertainty_score":0.3549188},"labels":[],"label_agreement":null},{"id":"W2978295770","doi":"10.3390/ijms20205212","title":"Trans-Kingdom Conjugation within Solid Media from Escherichia coli to Saccharomyces cerevisiae","year":2019,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Advanced Research Projects Agency; Defense Advanced Research Projects Agency; U.S. Department of Defense","keywords":"Plasmid; Bacterial conjugation; Electroporation; DNA; Escherichia coli; Pilus; Saccharomyces cerevisiae; Exogenous DNA; Biology; Transformation (genetics); Chemistry; Cell biology; Genetics; Yeast; Gene","score_opus":0.010255921757414136,"score_gpt":0.3069265214931456,"score_spread":0.29667059973573146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978295770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9621682,0.0005467802,0.035015855,0.0006463171,0.0012851157,0.00007060688,0.00001081381,0.0000034818054,0.00025279846],"genre_scores_gemma":[0.99075776,0.00005018859,0.008375702,0.0004998619,0.00027928487,0.0000014511528,0.000008881438,0.000008513174,0.000018379278],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988411,0.000032298554,0.0003085373,0.0001897856,0.00050784135,0.000120428485],"domain_scores_gemma":[0.9994003,0.000023111932,0.0001602969,0.00009700405,0.00022990127,0.00008938687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003361005,0.000101562364,0.00012976347,0.000104122206,0.00002561034,0.00008659208,0.000582197,0.000053232674,0.00006744473],"category_scores_gemma":[0.00010370716,0.00008884871,0.00009465495,0.00010180756,0.000048783284,0.0000145213635,0.00005388179,0.00007821377,0.000010038916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040837065,0.000016923246,0.0011937058,0.0000018423119,0.00006858685,0.000010045405,0.00025877295,0.0141666895,0.9829092,0.0001200684,0.00008645413,0.0011268925],"study_design_scores_gemma":[0.00053657347,0.00031913436,0.0044496553,0.0000750261,0.00001737901,0.000023768025,0.00028261702,0.0006706607,0.98798144,0.00032082124,0.0051533976,0.00016950836],"about_ca_topic_score_codex":0.000021317535,"about_ca_topic_score_gemma":0.000012584929,"teacher_disagreement_score":0.028589506,"about_ca_system_score_codex":0.0000146569355,"about_ca_system_score_gemma":0.00010584613,"threshold_uncertainty_score":0.36231455},"labels":[],"label_agreement":null},{"id":"W2978726884","doi":"10.1016/j.molcel.2019.09.012","title":"Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6","year":2019,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de Recherche du Québec - Santé; French Infrastructure for Integrated Structural Biology; National Institutes of Health; Agence Nationale de la Recherche","keywords":"CRISPR; Biology; Allosteric regulation; Cas9; DNA; Computational biology; Gene; Genetics; Receptor","score_opus":0.002630197039431335,"score_gpt":0.22571061009440446,"score_spread":0.22308041305497311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978726884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783864,0.0017369669,0.015188308,0.00023645273,0.0001120654,0.0004478261,0.000011106417,0.000016510507,0.0038643517],"genre_scores_gemma":[0.9965669,0.00003031119,0.0003188223,0.00043169426,0.00005163206,0.000031421492,0.00011288083,0.00003560963,0.002420747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991291,0.00004251876,0.0001376577,0.0003033074,0.0001369664,0.0002504331],"domain_scores_gemma":[0.999431,0.0000029610787,0.000037713773,0.00044270445,0.000032577427,0.000053000513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097979784,0.00015981232,0.00010114808,0.000019483754,0.000042207947,0.00003295474,0.00015108511,0.00010777282,0.000045732962],"category_scores_gemma":[0.000009116102,0.00013198619,0.000089144814,0.000078801735,0.000026819696,0.0000023447926,0.00010888472,0.0001015619,0.00010717391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008117653,0.000027596798,0.00010017523,0.000027580703,0.000013724688,0.000008144118,0.000023891294,0.00028463337,0.9967846,0.0000142531,0.002288188,0.00041904638],"study_design_scores_gemma":[0.00035419577,0.00012434451,0.00008115103,0.000008780713,0.000010535719,0.000013831105,0.00003905736,0.0001112383,0.9392053,0.000016230199,0.059855856,0.0001794855],"about_ca_topic_score_codex":0.000013450214,"about_ca_topic_score_gemma":0.000002445448,"teacher_disagreement_score":0.057579357,"about_ca_system_score_codex":0.000008246936,"about_ca_system_score_gemma":0.000024156927,"threshold_uncertainty_score":0.5382241},"labels":[],"label_agreement":null},{"id":"W2978957730","doi":"10.1101/792929","title":"Transgene-mediated skeletal phenotypic variation in zebrafish","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"Biology; Zebrafish; Transgene; Transposable element; Transgenesis; Genetics; Phenotype; Danio; Genome; Transcription activator-like effector nuclease; Genome editing; Model organism; Gene; Computational biology","score_opus":0.006305307096324711,"score_gpt":0.2275414077714352,"score_spread":0.2212361006751105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978957730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96930355,0.0022742157,0.026224533,0.00007445907,0.001210371,0.0006387955,0.00016513288,0.00009043704,0.000018529763],"genre_scores_gemma":[0.99705416,0.00038389376,0.0016565736,0.00012946394,0.0005296651,0.00010669047,0.0000058158284,0.00012474177,0.000009010335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778765,0.000082521925,0.00046447752,0.0009373679,0.00023022649,0.0004977748],"domain_scores_gemma":[0.99852335,0.000018578374,0.00015759803,0.0009990142,0.00015486077,0.00014660708],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035139493,0.00046964106,0.00040691998,0.0001934008,0.00003972348,0.000072854804,0.00042302278,0.00078441546,0.00002944336],"category_scores_gemma":[0.00012616502,0.0005623371,0.00015946639,0.0002503084,0.000040106268,0.000006972044,0.00023257722,0.00049045926,0.000053886914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002486132,0.000076597236,0.0022358194,0.00021455725,0.00008763827,0.000007768592,0.000008744275,0.0034938618,0.9937023,0.00002173986,0.00012438699,0.0000017207705],"study_design_scores_gemma":[0.0011249968,0.00009851367,0.2936028,0.0001591005,0.00006624237,2.0405512e-8,0.0000017078695,0.0017792078,0.694624,0.0000012890501,0.0075627877,0.0009793282],"about_ca_topic_score_codex":0.00003636256,"about_ca_topic_score_gemma":0.000012669959,"teacher_disagreement_score":0.2990783,"about_ca_system_score_codex":0.000081601516,"about_ca_system_score_gemma":0.00034481057,"threshold_uncertainty_score":0.9996828},"labels":[],"label_agreement":null},{"id":"W2979134593","doi":"10.1101/788372","title":"A method for rapid selection of randomly induced mutations in a gene of interest using CRISPR/Cas9 mediated activation of gene expression","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Toronto","keywords":"CRISPR; Allele; Phenotype; Biology; Genetics; Gene; Cas9; Mutant; Mutation; Point mutation; Function (biology); Loss function; Gene expression","score_opus":0.029718019248889265,"score_gpt":0.30840793565822194,"score_spread":0.27868991640933266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979134593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6809847,0.00024976803,0.31782785,0.000007091604,0.0001530465,0.00065143756,0.00011585413,0.000009798207,4.962851e-7],"genre_scores_gemma":[0.9163185,0.000071335446,0.08335285,0.00000731988,0.00009162166,0.00009202457,0.000007624056,0.0000581887,5.4349294e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983415,0.0001294855,0.0006995257,0.00048265158,0.00013499254,0.00021187164],"domain_scores_gemma":[0.9981867,0.00008186649,0.00063093106,0.00045741868,0.00058687775,0.00005621428],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005557245,0.00027284768,0.0005442506,0.00034814526,0.000023508434,0.00000999115,0.00020196763,0.0005030156,0.0000050115223],"category_scores_gemma":[0.00040203545,0.0003041315,0.0001613643,0.00030634258,0.000031796768,0.000009169538,0.00012961296,0.00019818245,1.7064922e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030010892,0.000106602136,0.0010468793,0.0006023452,0.00011597698,2.8232702e-7,0.000022864993,0.009411571,0.98837453,0.000005356516,0.0000072482458,0.000006233621],"study_design_scores_gemma":[0.0017339071,0.00015614329,0.0051673916,0.0003646406,0.000079918085,2.6583464e-8,0.000008583855,0.0092661055,0.9829435,9.581506e-7,0.000028255474,0.00025058616],"about_ca_topic_score_codex":0.000070883776,"about_ca_topic_score_gemma":0.0000044473013,"teacher_disagreement_score":0.23533383,"about_ca_system_score_codex":0.00005434005,"about_ca_system_score_gemma":0.00035544185,"threshold_uncertainty_score":0.99994105},"labels":[],"label_agreement":null},{"id":"W2979237553","doi":"10.1101/790014","title":"Access to unexplored regions of sequence space in directed enzyme evolution <i>via</i> insertion/deletion mutagenesis","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Directorate for Biological Sciences; Horizon 2020 Framework Programme; University of Cambridge; Science and Technology Facilities Council; Dell EMC","keywords":"Mutagenesis; Genetics; INDEL Mutation; Biology; Sequence space; Indel; Directed evolution; Point mutation; Computational biology; Triad (sociology); Mutation; Gene; Mutant; Genotype","score_opus":0.016915415668233916,"score_gpt":0.2662419911848773,"score_spread":0.2493265755166434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979237553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8975092,0.0011319689,0.09957714,0.00018807995,0.0006032836,0.0007763237,0.00010989386,0.0000983978,0.0000056969966],"genre_scores_gemma":[0.9961749,0.00039731278,0.002840467,0.00008413671,0.00019831548,0.0002028553,0.000004572768,0.000088979315,0.000008465688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978564,0.000105849285,0.00049766904,0.00088347896,0.0002511301,0.00040550088],"domain_scores_gemma":[0.99802494,0.000017021031,0.00024223466,0.0011656007,0.00038825968,0.0001619405],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002984755,0.00040327891,0.0004230555,0.00033356462,0.000045083674,0.00005605805,0.0005580368,0.000528092,0.000005772708],"category_scores_gemma":[0.00020254958,0.00048358846,0.00013549723,0.0006247056,0.00005335618,0.000016001386,0.00055085646,0.000276455,0.000012189733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057281177,0.00007172592,0.008204421,0.00023807432,0.000051625633,0.000004979955,0.000008001136,0.023618914,0.96745235,0.000040971918,0.00024953435,0.0000021336903],"study_design_scores_gemma":[0.0003282351,0.00007293505,0.13217126,0.00028554854,0.000040816354,3.1949313e-8,0.000002750582,0.0015734736,0.86383146,0.0000018973828,0.0011883576,0.0005032351],"about_ca_topic_score_codex":0.00026030626,"about_ca_topic_score_gemma":0.00004725968,"teacher_disagreement_score":0.12396684,"about_ca_system_score_codex":0.00018030903,"about_ca_system_score_gemma":0.00035874333,"threshold_uncertainty_score":0.9997616},"labels":[],"label_agreement":null},{"id":"W2979457236","doi":"10.1089/crispr.2019.29071.bkn","title":"From Poetry to Policy: An Interview with Bartha Maria Knoppers","year":2019,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Poetry; Library science; Download; Art history; Art; Sociology; Media studies; World Wide Web; Computer science; Literature","score_opus":0.0076522346400252446,"score_gpt":0.30772287406983295,"score_spread":0.3000706394298077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979457236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9779712,0.0009433439,0.016787242,0.0027084525,0.00031043784,0.00012409777,0.000010767069,0.000009341447,0.0011351021],"genre_scores_gemma":[0.9951406,0.00012976756,0.0011319664,0.0016021836,0.0011919757,0.000002993646,0.000012129532,0.000028670302,0.0007596952],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992319,0.00007085611,0.00014417626,0.00018240148,0.00012755058,0.00024313986],"domain_scores_gemma":[0.9993172,0.000008264239,0.000040181207,0.00040249983,0.00005142116,0.00018039385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024290137,0.00013725826,0.000121487756,0.00005884973,0.00007295851,0.00007405527,0.00034840577,0.000059715512,0.00019949929],"category_scores_gemma":[0.000021262616,0.000087365835,0.000063643434,0.000103718674,0.000021971586,0.0000051231823,0.000093763934,0.00018734494,0.00007051645],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028418857,0.000064482614,0.0042586667,0.000019092553,0.0002572032,0.000015648555,0.0013664622,0.0039226203,0.9524151,0.00011456924,0.011674608,0.025607327],"study_design_scores_gemma":[0.0025539694,0.0031052472,0.04026306,0.00025181074,0.00014858818,0.0010394587,0.004284932,0.0005417181,0.37986168,0.00052801875,0.5663535,0.0010680247],"about_ca_topic_score_codex":0.0000469781,"about_ca_topic_score_gemma":0.000031485382,"teacher_disagreement_score":0.57255346,"about_ca_system_score_codex":0.000015263726,"about_ca_system_score_gemma":0.00007330964,"threshold_uncertainty_score":0.35626754},"labels":[],"label_agreement":null},{"id":"W2979579934","doi":"10.1158/0008-5472.can-19-1961","title":"Upregulation of Myt1 Promotes Acquired Resistance of Cancer Cells to Wee1 Inhibition","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northern Alberta Institute of Technology; Alberta Cancer Foundation; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Downregulation and upregulation; Wee1; Cancer; Biology; Cancer research; Cell cycle; Genetics; Gene; Cyclin-dependent kinase 1","score_opus":0.021067084947624954,"score_gpt":0.3901589490972172,"score_spread":0.3690918641495923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979579934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963987,0.0020780112,0.0004925626,0.00016400006,0.000099590165,0.00036644685,0.000040916675,0.00000346919,0.00035629587],"genre_scores_gemma":[0.9970584,0.00027147736,0.00028784556,0.000011407217,0.00009879709,0.00007012284,0.000014010781,0.0000149321895,0.0021730321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991656,0.000035035388,0.00015550437,0.00021586593,0.00023671724,0.0001912895],"domain_scores_gemma":[0.9993589,0.000012016423,0.0000362927,0.00026360017,0.00027926947,0.00004991074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023605772,0.00006506637,0.00010917149,0.0000717888,0.000019739347,0.000005638793,0.00010389564,0.00007059724,0.000100538535],"category_scores_gemma":[0.000025347366,0.00006548405,0.000035127283,0.0002088634,0.000046507517,0.0000028610327,0.00007458945,0.000044191023,0.000004798675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001192838,0.000015655687,0.0011078208,0.00020456333,0.000016177308,1.5118152e-7,0.00012591486,0.002087313,0.99400204,0.000029116922,0.0012469671,0.001044996],"study_design_scores_gemma":[0.00022918536,0.00011256359,0.004681106,0.00014388999,0.000003425041,8.50957e-8,0.00004586918,0.000040842682,0.99016285,0.000030614065,0.004480433,0.000069126174],"about_ca_topic_score_codex":0.00014883988,"about_ca_topic_score_gemma":0.00026646833,"teacher_disagreement_score":0.0038391806,"about_ca_system_score_codex":0.000030149457,"about_ca_system_score_gemma":0.00010355849,"threshold_uncertainty_score":0.2670362},"labels":[],"label_agreement":null},{"id":"W2979865448","doi":"10.1038/s41598-019-51090-3","title":"A one-step tRNA-CRISPR system for genome-wide genetic interaction mapping in mammalian cells","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Terry Fox Foundation; Cure Brain Cancer Foundation; Government of Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Québec Consortium for Drug Discovery; European Hematology Association","keywords":"CRISPR; Computational biology; Gene; Genome; Biology; Genome editing; Barcode; Genetic screen; Drug discovery; Genetics; Computer science; Bioinformatics; Phenotype","score_opus":0.009485455131834783,"score_gpt":0.2575504723886465,"score_spread":0.24806501725681168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979865448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96783906,0.00042863644,0.023538081,0.000023617602,0.006809094,0.00071924867,0.0000032125588,0.000021923448,0.0006171098],"genre_scores_gemma":[0.993764,0.0000066429684,0.0033354235,0.000018894689,0.00013635683,0.000062123545,0.00008875037,0.00002808104,0.002559741],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998258,0.00002314806,0.00047216465,0.0007293429,0.00017435738,0.00034298224],"domain_scores_gemma":[0.9989833,0.000011257009,0.00015440464,0.0006828271,0.00008516258,0.00008301034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055501366,0.00014702657,0.00018005166,0.00016189125,0.00006863873,0.00010956539,0.0001282043,0.00010573922,0.000019452094],"category_scores_gemma":[0.00003654176,0.00016501786,0.00011619362,0.00017585952,0.000028934423,0.0000066593675,0.00007188532,0.00006997348,0.00002659611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012548413,0.000027069027,0.006076484,0.00021192324,0.000016844584,0.000021784348,0.000100437595,0.0048234463,0.9868534,0.000002989407,0.0007134264,0.0011396488],"study_design_scores_gemma":[0.00040569296,0.00008444788,0.011708617,0.00011693318,0.000017530672,0.000108573404,0.0006043533,0.0017335152,0.8158875,0.000038464856,0.16893962,0.00035472788],"about_ca_topic_score_codex":0.000025765756,"about_ca_topic_score_gemma":0.000043945358,"teacher_disagreement_score":0.17096588,"about_ca_system_score_codex":0.00005818465,"about_ca_system_score_gemma":0.000061511375,"threshold_uncertainty_score":0.6729233},"labels":[],"label_agreement":null},{"id":"W2980114851","doi":"10.1101/800011","title":"Multi-model functionalization of disease-associated <i>PTEN</i> missense mutations identifies multiple molecular mechanisms underlying protein dysfunction","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Simons Foundation Autism Research Initiative; Simons Foundation","keywords":"PTEN; Missense mutation; Phenotype; Biology; Genetics; Nonsense mutation; Loss function; Computational biology; Mutation; PI3K/AKT/mTOR pathway; Gene; Signal transduction","score_opus":0.015518277270258214,"score_gpt":0.24988460488913306,"score_spread":0.23436632761887485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980114851","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5075563,0.00053213525,0.4905525,0.000022451353,0.0003758015,0.0006608534,0.0002286536,0.00007003953,0.0000012526915],"genre_scores_gemma":[0.98924476,0.000061078186,0.010151802,0.000053317755,0.00004720502,0.00022632636,0.000039417282,0.00013281172,0.000043279782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978722,0.0000944559,0.00051248487,0.0008243202,0.00035519412,0.00034136153],"domain_scores_gemma":[0.99790657,0.00001711857,0.0003930548,0.00084644096,0.0006671457,0.00016968354],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029381568,0.00044107935,0.00034842445,0.00017910163,0.00011669105,0.00008049922,0.0002449944,0.00048326596,0.0000090181065],"category_scores_gemma":[0.00042522833,0.0005369105,0.00023290487,0.00022185197,0.000060823644,0.000013721276,0.00025191111,0.00025892752,0.000009084016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004519378,0.0001550964,0.0003769513,0.0003264314,0.00018292917,0.00000453529,0.0000048266234,0.16585556,0.8329169,0.00009408264,0.000036998757,4.9902775e-7],"study_design_scores_gemma":[0.0008443158,0.000053042546,0.010941746,0.00029264297,0.00020313977,1.6311878e-8,0.000007727601,0.1287784,0.8582112,0.00001609478,0.00005575739,0.000595914],"about_ca_topic_score_codex":0.000021475484,"about_ca_topic_score_gemma":0.0000075323637,"teacher_disagreement_score":0.48168847,"about_ca_system_score_codex":0.00009349932,"about_ca_system_score_gemma":0.00043235492,"threshold_uncertainty_score":0.99970824},"labels":[],"label_agreement":null},{"id":"W2980262914","doi":"10.1089/crispr.2019.0019","title":"Heritable Genome Editing: Who Speaks for “Future” Children?","year":2019,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Clinical trial; Genome editing; Medicine; Genome; Genetics; Pathology; Biology; Gene","score_opus":0.004312620294513896,"score_gpt":0.2667454569251332,"score_spread":0.2624328366306193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980262914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96004075,0.005492632,0.03033776,0.0009926999,0.0013569493,0.00033844035,0.000020021613,0.000012386173,0.001408337],"genre_scores_gemma":[0.98871136,0.00043826917,0.001034778,0.00034156253,0.007248507,0.000007986161,0.000026822583,0.000039299724,0.0021514024],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999199,0.000023724986,0.00017977903,0.0001667114,0.00011182188,0.0003190093],"domain_scores_gemma":[0.9994839,0.000009077579,0.00006984467,0.0002794542,0.00007392147,0.00008382923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034973468,0.00013449193,0.0001282742,0.000024726654,0.00016160322,0.00007044319,0.0003020474,0.00008108876,0.00009629497],"category_scores_gemma":[0.000024191753,0.00009685382,0.00014181292,0.00004339501,0.000022184026,0.000004206843,0.00006518613,0.00018785875,0.000022775921],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017162321,0.000074452124,0.0077744965,0.000051413244,0.0003898212,0.000003570422,0.0005148772,0.005224798,0.94147515,0.00036286918,0.038574588,0.005382329],"study_design_scores_gemma":[0.0024084935,0.00081262126,0.040290438,0.00003951988,0.00011275001,0.0011578068,0.0011387344,0.0004558987,0.24286844,0.0004974501,0.7095859,0.00063192914],"about_ca_topic_score_codex":0.000002294442,"about_ca_topic_score_gemma":0.0000025133807,"teacher_disagreement_score":0.6986067,"about_ca_system_score_codex":0.000010887537,"about_ca_system_score_gemma":0.000033287637,"threshold_uncertainty_score":0.39495844},"labels":[],"label_agreement":null},{"id":"W2980305594","doi":"10.1089/crispr.2019.0020","title":"Attitudes of Members of Genetics Professional Societies Toward Human Gene Editing","year":2019,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Human Genome Research Institute","keywords":"Germline; Genome editing; Human genetics; Somatic cell; Genetics; Biology; Gene; Genome","score_opus":0.014107497515855274,"score_gpt":0.33833410377322704,"score_spread":0.32422660625737176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980305594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99483097,0.0024111322,0.0014209355,0.00014344016,0.0005245766,0.00008965101,0.0000068174268,0.0000030981337,0.0005693904],"genre_scores_gemma":[0.99753046,0.00029006027,0.0011179848,0.000053590313,0.0005068794,0.0000017392939,0.0000068278955,0.000016760647,0.000475725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914527,0.000045788653,0.00030201042,0.000108143206,0.0002222667,0.00017653035],"domain_scores_gemma":[0.9994138,0.000014982362,0.00018278531,0.0002050906,0.00013816578,0.000045165598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039216038,0.000106882806,0.00015679076,0.00002777927,0.000081723934,0.000010811815,0.00027375712,0.00008134161,0.00009065095],"category_scores_gemma":[0.000023144827,0.000076388314,0.00014012452,0.000043808683,0.00009131825,0.0000028298643,0.000120074634,0.00017578332,0.0000017276453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016744798,0.00003502101,0.0071227243,0.00007417594,0.00009064204,5.36863e-7,0.0003188323,0.0022359232,0.9859748,0.00003186598,0.0038468018,0.00025197238],"study_design_scores_gemma":[0.00038276886,0.00018461433,0.013404556,0.00005458893,0.000032558983,0.000069386726,0.00072668295,0.00008869523,0.98298866,0.00010603054,0.0018589633,0.0001025201],"about_ca_topic_score_codex":0.000002829231,"about_ca_topic_score_gemma":0.0000016697843,"teacher_disagreement_score":0.006281831,"about_ca_system_score_codex":0.000007340228,"about_ca_system_score_gemma":0.00005547751,"threshold_uncertainty_score":0.31150252},"labels":[],"label_agreement":null},{"id":"W2980448661","doi":"10.1051/medsci/2019153","title":"Chromosomes synthétiques","year":2019,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Humanities; Genome; Philosophy; Biology; Genetics; Gene","score_opus":0.037217052628717384,"score_gpt":0.3758398076400568,"score_spread":0.3386227550113394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980448661","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019897306,0.9805722,0.0015549102,0.00027164066,0.0018773817,0.0005311839,0.000074224976,0.000028726203,0.01309997],"genre_scores_gemma":[0.00859043,0.98136306,0.0021640155,0.00015427917,0.0012750123,0.00004690346,0.000092436574,0.00005975145,0.006254108],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99687594,0.00015426967,0.00064089824,0.0011729118,0.00038385528,0.0007721519],"domain_scores_gemma":[0.9988092,0.00013344604,0.00023695033,0.0005952065,0.00006909877,0.00015606637],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006707179,0.00067598326,0.0010738311,0.00016514205,0.00026551803,0.00015713993,0.0010466977,0.00057575747,0.00047068414],"category_scores_gemma":[0.00019803098,0.0005666638,0.0005543618,0.0004669241,0.0006724854,0.0000094775505,0.0003851741,0.00027294026,0.0005724751],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000140932425,0.00042633602,0.002518063,0.022894302,0.0007072409,0.000036720106,0.00011037091,0.002419866,0.013717476,0.005701658,0.023642307,0.92781156],"study_design_scores_gemma":[0.00020232321,0.0007099145,0.00013654244,0.0027089464,0.0002613315,0.000120640856,0.000048418577,0.00013899268,0.0044598174,0.00006360964,0.9904038,0.0007457188],"about_ca_topic_score_codex":0.00003029052,"about_ca_topic_score_gemma":0.000016877186,"teacher_disagreement_score":0.9667614,"about_ca_system_score_codex":0.00004400576,"about_ca_system_score_gemma":0.0005656756,"threshold_uncertainty_score":0.9996785},"labels":[],"label_agreement":null},{"id":"W2980811738","doi":"10.1038/s41467-019-12726-0","title":"Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Terry Fox Foundation; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Human Frontier Science Program; Hospital for Sick Children; University of Toronto; National Cancer Institute; Ontario Institute for Cancer Research; Government of Canada; Government of Ontario","keywords":"Haematopoiesis; CRISPR; Biology; Stem cell; Hematopoietic stem cell; Cell biology; Genome editing; Computational biology; Cas9; Genetics; Gene","score_opus":0.017998021706195255,"score_gpt":0.31089018702829113,"score_spread":0.2928921653220959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980811738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883164,0.006360043,0.0030620447,0.00013819394,0.00033382763,0.00028702486,0.000024847564,0.000026753543,0.0014508233],"genre_scores_gemma":[0.99734175,0.00008791514,0.0015613984,0.00005916595,0.00007733191,0.000015723332,0.000309123,0.000021377056,0.0005262272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931604,0.000037430604,0.00021017433,0.0001845412,0.00011722671,0.00013457683],"domain_scores_gemma":[0.9984339,0.00003020824,0.000080353166,0.0012673436,0.00014570734,0.000042487703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000958347,0.00011405168,0.00012555635,0.000053629265,0.00008070015,0.000013245805,0.00045604212,0.00024600318,0.000032347376],"category_scores_gemma":[0.000010642816,0.000118214244,0.000086731925,0.00011698426,0.000056693985,0.0000037143361,0.00024916546,0.00028574106,0.000014371479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000064072383,0.000104791514,0.008450172,0.000047819383,0.000036002642,1.7152668e-7,0.000036020567,0.00017567327,0.98969144,0.0005401238,0.0007772961,0.00013408816],"study_design_scores_gemma":[0.0002969367,0.00008725301,0.009931157,0.00003331641,0.00002468992,0.000008190718,0.00007131869,0.000076025746,0.9866094,0.000012983138,0.002701112,0.00014762391],"about_ca_topic_score_codex":0.0000016387039,"about_ca_topic_score_gemma":0.000028605748,"teacher_disagreement_score":0.009025296,"about_ca_system_score_codex":0.000013331656,"about_ca_system_score_gemma":0.000027624603,"threshold_uncertainty_score":0.48206368},"labels":[],"label_agreement":null},{"id":"W2981015241","doi":"10.1038/s41596-019-0221-z","title":"Magnetically guided virus stamping for the targeted infection of single cells or groups of cells","year":2019,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Transduction (biophysics); Virus; Cell biology; Transgene; Biology; Cell culture; Cell; Virology; Nanotechnology; Biophysics; Materials science; Genetics; Gene","score_opus":0.011639307553013983,"score_gpt":0.3290087527624785,"score_spread":0.31736944520946453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981015241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7790233,0.0008627832,0.08573034,0.00010356672,0.00073112943,0.13252294,0.00015591015,0.000039673207,0.0008303407],"genre_scores_gemma":[0.98472303,0.000021698752,0.0055347043,0.0000880665,0.00015006364,0.008996767,0.00001973326,0.000030088151,0.00043585122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992522,0.000021739708,0.000252861,0.00019371272,0.00011923243,0.00016027296],"domain_scores_gemma":[0.9993279,0.00005028205,0.000109466826,0.0003167448,0.00016761107,0.000028023636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019235573,0.00011863747,0.0001589524,0.000029908664,0.000022803453,0.000010271529,0.00015509431,0.0002706178,0.00004312387],"category_scores_gemma":[0.00008130294,0.000082060214,0.00010376652,0.000094794785,0.000032142307,0.0000024932272,0.00005776428,0.00012318457,0.0000016428228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023730079,0.00006630225,0.00017403148,0.00030085447,0.00003062068,1.205873e-7,0.000022663484,0.0011637013,0.99599683,0.00003520349,0.00095289946,0.0010194774],"study_design_scores_gemma":[0.00069670763,0.000913184,0.00051980047,0.000050814346,0.000015948113,0.0000013916275,0.000007684216,0.00029890487,0.9511527,0.000026996224,0.046213835,0.00010205715],"about_ca_topic_score_codex":0.000011799012,"about_ca_topic_score_gemma":0.000020600395,"teacher_disagreement_score":0.20569971,"about_ca_system_score_codex":0.0000075621742,"about_ca_system_score_gemma":0.000042581058,"threshold_uncertainty_score":0.33463183},"labels":[],"label_agreement":null},{"id":"W2981655730","doi":"10.1111/mec.15185","title":"Genome structure predicts modular transcriptome responses to genetic and environmental conditions","year":2019,"lang":"en","type":"article","venue":"Molecular Ecology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Transcriptome; Genome; Computational biology; Modular design; Genetics; Evolutionary biology; Gene; Gene expression","score_opus":0.0022910633075807364,"score_gpt":0.2235145678281129,"score_spread":0.22122350452053216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981655730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947092,0.0008519206,0.0034817087,0.00012259652,0.00015875052,0.00040370302,0.00019120435,0.000014105289,0.00006680392],"genre_scores_gemma":[0.9972871,0.00005261332,0.0013813331,0.00060002116,0.000040485218,0.000027761529,0.00022110078,0.000033648255,0.00035594837],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901736,0.000050286595,0.00014954533,0.00041343353,0.00008347665,0.00028592692],"domain_scores_gemma":[0.9994952,0.0000071748914,0.0000216476,0.0003249649,0.00001038124,0.0001406205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041968597,0.00016994722,0.0001543113,0.00007883972,0.000044825207,0.000013371441,0.00013228667,0.00016925651,0.00016801534],"category_scores_gemma":[0.0000156472,0.00018932202,0.000052743944,0.00004741276,0.00005372409,0.000002122801,0.000091108566,0.00007980036,0.000027746446],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037316375,0.000018432836,0.013448717,0.000012693485,0.000051749794,0.000020041658,0.00006116388,0.00599802,0.98024005,0.000017214334,0.00002877447,0.0000658484],"study_design_scores_gemma":[0.0007861819,0.0007933675,0.75727296,0.000003920027,0.00004072954,0.00016514183,0.00006949127,0.00027066207,0.2283791,0.00009337729,0.011786981,0.00033809643],"about_ca_topic_score_codex":0.0000020700204,"about_ca_topic_score_gemma":0.000009495317,"teacher_disagreement_score":0.7518609,"about_ca_system_score_codex":0.00001608509,"about_ca_system_score_gemma":0.000022548864,"threshold_uncertainty_score":0.7720328},"labels":[],"label_agreement":null},{"id":"W2981743254","doi":"10.1371/journal.pone.0224113","title":"Off-target effects of CRISPRa on interleukin-6 expression","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Heart Research Centre; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Biology; Transcription factor; Computational biology; Genome editing; HEK 293 cells; Regulation of gene expression; Downregulation and upregulation; Cell biology; Gene; Genetics","score_opus":0.007101644815942645,"score_gpt":0.24237774177580473,"score_spread":0.2352760969598621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981743254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966444,0.0007522206,0.0006677141,0.000017736187,0.000085709995,0.00018308831,0.0000033031831,0.000009760903,0.0016360949],"genre_scores_gemma":[0.99713415,0.000090709524,0.0016759951,0.00006686438,0.000085575935,0.000011190974,0.000019384144,0.000017268532,0.0008988663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994674,0.000015597629,0.00010347661,0.00017572875,0.00011762295,0.00012021798],"domain_scores_gemma":[0.9995937,0.0000177008,0.000032405558,0.0002882928,0.000030150934,0.00003774742],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003933945,0.000089137204,0.0001310903,0.000028688002,0.000009408606,0.000003893906,0.00010095645,0.00007438392,0.00003719017],"category_scores_gemma":[0.000054133634,0.00008258734,0.000045796452,0.000028499515,0.000010665756,0.0000011972396,0.00005898761,0.000057573066,0.000032558564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004668768,0.00027438122,0.0016653765,0.00021547223,0.000050704693,7.738098e-7,0.000028815153,0.00007265617,0.99709266,0.000010566694,0.0002609464,0.0002809719],"study_design_scores_gemma":[0.00038048028,0.0005728736,0.0015458912,0.00022140046,0.000015408677,3.7120392e-7,0.000008762955,0.00010953524,0.9960772,0.00001208517,0.00096076005,0.000095230746],"about_ca_topic_score_codex":0.0000013007748,"about_ca_topic_score_gemma":4.0128276e-7,"teacher_disagreement_score":0.0010154472,"about_ca_system_score_codex":0.000004353817,"about_ca_system_score_gemma":0.00000856593,"threshold_uncertainty_score":0.3367814},"labels":[],"label_agreement":null},{"id":"W2982038705","doi":"10.1038/s41467-019-12829-8","title":"Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; McGill University","funders":"Japan Agency for Medical Research and Development; Compute Canada; Genome Canada","keywords":"Genome editing; Biology; Genetics; Computational biology; Gene; Homologous recombination; Cas9; CRISPR; Nuclease; DNA repair; Human genome; Genome","score_opus":0.009843258708605812,"score_gpt":0.29008568493510767,"score_spread":0.28024242622650186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982038705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762644,0.012393095,0.0048134294,0.0010737344,0.0002219606,0.00041627084,0.00008899669,0.000046914352,0.00468119],"genre_scores_gemma":[0.9769452,0.0011436706,0.02092853,0.00007554604,0.000050262726,0.000029285015,0.00057181844,0.0000139052545,0.00024178268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992748,0.000057977843,0.00024168979,0.00019262433,0.000074371696,0.00015855517],"domain_scores_gemma":[0.9980777,0.0001168204,0.00010486041,0.0014903182,0.00017744758,0.000032892272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018497882,0.00010913681,0.00013084209,0.000055938384,0.0000936135,0.000012401926,0.0008384806,0.00029402558,0.000018449316],"category_scores_gemma":[0.0005753693,0.00010228785,0.000077800185,0.0001288382,0.000112801106,0.0000047588956,0.0004805221,0.00029629172,0.000011456082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001349492,0.000059161925,0.013829019,0.000022211922,0.000044790348,2.6982235e-7,0.0000625553,0.0012096472,0.98293304,0.00046654177,0.0009952914,0.00036398182],"study_design_scores_gemma":[0.0012197867,0.00048961205,0.13198039,0.00008674799,0.000084877815,0.000037241993,0.00071483455,0.0005479425,0.61530405,0.0019619388,0.24695706,0.0006155428],"about_ca_topic_score_codex":0.0000075866083,"about_ca_topic_score_gemma":0.00005967153,"teacher_disagreement_score":0.36762902,"about_ca_system_score_codex":0.000013732726,"about_ca_system_score_gemma":0.000036785124,"threshold_uncertainty_score":0.41711774},"labels":[],"label_agreement":null},{"id":"W2982054941","doi":"10.1101/815431","title":"A method to estimate the frequency of chromosomal rearrangements induced by CRISPR/Cas9 multiplexing in Drosophila","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"CRISPR; Biology; Polytene chromosome; Chromosomal inversion; Genetics; Breakpoint; Cas9; Germline; Chromosomal translocation; Genome editing; Chromosome; Karyotype; Computational biology; Gene","score_opus":0.013422767355175266,"score_gpt":0.30992410091475714,"score_spread":0.29650133355958186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982054941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98099494,0.0011476898,0.015879499,0.00016187593,0.0005010235,0.0010272334,0.00023152733,0.000041113264,0.000015123884],"genre_scores_gemma":[0.97663355,0.000056283134,0.022661168,0.00012926839,0.00020411196,0.0001949764,0.0000026280397,0.00011325033,0.0000047686467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99756867,0.00014904258,0.00057183503,0.00090903265,0.00028650396,0.00051493704],"domain_scores_gemma":[0.998077,0.00003225203,0.0002410188,0.0012936466,0.00020216033,0.00015397466],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00070547895,0.0004816965,0.000495757,0.00015795838,0.000058125064,0.000059392616,0.00071707193,0.00050614466,0.00001007701],"category_scores_gemma":[0.00018545365,0.00046299328,0.0001449579,0.0003079523,0.00004141076,0.000006587924,0.00069089123,0.00047034246,0.000011702396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023876437,0.00006851017,0.0062435805,0.00022631786,0.00010286526,0.000005808153,0.000019666826,0.0035291621,0.9895812,0.00002641136,0.00016686559,0.0000056967224],"study_design_scores_gemma":[0.000517127,0.0001019671,0.059595507,0.00027066443,0.00004135746,2.984808e-8,0.0000040513223,0.00085792516,0.9370674,0.000001725135,0.0010279841,0.0005142989],"about_ca_topic_score_codex":0.00018371844,"about_ca_topic_score_gemma":0.000012992773,"teacher_disagreement_score":0.053351928,"about_ca_system_score_codex":0.00007618407,"about_ca_system_score_gemma":0.00021850581,"threshold_uncertainty_score":0.9997822},"labels":[],"label_agreement":null},{"id":"W2982062700","doi":"10.1038/s41467-019-12922-y","title":"Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Feldan (Canada)","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Global Affairs Canada; Roy J. Carver Charitable Trust; U.S. Department of Health and Human Services; National Institutes of Health; Cystic Fibrosis Foundation","keywords":"Cell biology; Ribonucleoprotein; Recombinant DNA; Biology; Chemistry; RNA; Biochemistry; Gene","score_opus":0.00632860295676501,"score_gpt":0.27386896738856276,"score_spread":0.26754036443179774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982062700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894684,0.008445014,0.00025856675,0.0006133368,0.00005624589,0.00038013147,0.00006352494,0.000022331193,0.0006924548],"genre_scores_gemma":[0.99448854,0.0007092659,0.0041899174,0.00014922826,0.000022672399,0.000028241304,0.0000973354,0.000019620531,0.00029519657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945074,0.00003406804,0.0001443777,0.00016042452,0.00007485837,0.00013555004],"domain_scores_gemma":[0.99881655,0.000037265872,0.000041653188,0.0009085754,0.00013302117,0.00006292738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102220096,0.000104933046,0.0001267828,0.000058536316,0.000055746503,0.00001145507,0.00037839616,0.00018675344,0.000010926056],"category_scores_gemma":[0.00016939783,0.00010713681,0.00004963856,0.00013504826,0.00003562847,0.000003786172,0.0002706023,0.00018790567,0.000008284398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014675644,0.000080321275,0.003280895,0.000025576182,0.00005766162,1.1437813e-7,0.00011206247,0.00031714834,0.9932801,0.00042934658,0.001707177,0.0006949022],"study_design_scores_gemma":[0.0007044754,0.0004126704,0.035678733,0.000114065435,0.000054185373,0.0000059043427,0.00023704665,0.00080331275,0.8626878,0.00007610251,0.09881429,0.00041140223],"about_ca_topic_score_codex":0.000042925647,"about_ca_topic_score_gemma":0.00017247452,"teacher_disagreement_score":0.1305923,"about_ca_system_score_codex":0.000010737998,"about_ca_system_score_gemma":0.000029419625,"threshold_uncertainty_score":0.43689123},"labels":[],"label_agreement":null},{"id":"W2982095232","doi":"10.1186/s13007-019-0500-2","title":"An optimised CRISPR/Cas9 protocol to create targeted mutations in homoeologous genes and an efficient genotyping protocol to identify edited events in wheat","year":2019,"lang":"en","type":"article","venue":"Plant Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Plant Biotechnology Institute; Communications Research Centre Canada; University of Ottawa","funders":"National Research Council Canada; Agriculture and Agri-Food Canada","keywords":"CRISPR; Genetics; Biology; Genotyping; Gene; Protocol (science); Computational biology; Genotype; Medicine","score_opus":0.018370749519925126,"score_gpt":0.43615333593707295,"score_spread":0.4177825864171478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982095232","genre_codex":"empirical","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7213892,0.000014520773,0.0843472,0.000032317686,0.00009700842,0.19402839,0.0000295402,0.000023786628,0.000038028047],"genre_scores_gemma":[0.19540094,0.0000017497562,0.24623848,0.00013441683,0.00015017304,0.55781204,0.00015229631,0.000052273535,0.00005765942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998244,0.00033397903,0.00034905897,0.0005793836,0.00011744946,0.00037616817],"domain_scores_gemma":[0.9992798,0.00003388217,0.000046504192,0.0003760324,0.000053032127,0.00021072468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080377446,0.00021984366,0.00024772316,0.00026234606,0.00004525172,0.000030505142,0.00019891579,0.00015312966,0.000019459476],"category_scores_gemma":[0.00009975037,0.0002172174,0.000032475382,0.00025879336,0.000013259934,0.000008110453,0.00010790347,0.000114783084,0.0000053335975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032168475,0.00013230667,0.0065763826,0.00008840867,0.000010929232,0.000007402456,0.00042562315,0.117537275,0.87067485,0.000002594838,0.000015432945,0.004207123],"study_design_scores_gemma":[0.0022221257,0.0008981646,0.08501289,0.000104081344,0.000011775431,0.000028320697,0.00019975532,0.036077403,0.871586,0.000020800142,0.0033361688,0.00050246355],"about_ca_topic_score_codex":0.000099572906,"about_ca_topic_score_gemma":0.0001311206,"teacher_disagreement_score":0.5259883,"about_ca_system_score_codex":0.000029303095,"about_ca_system_score_gemma":0.000051406023,"threshold_uncertainty_score":0.88578683},"labels":[],"label_agreement":null},{"id":"W2982443853","doi":"10.1101/825166","title":"CRISPR/Cas9 mediated intersectional knockout of GSK3β in D2 receptor expressing mPFC neurons reveals contributions to emotional regulation","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Prefrontal cortex; Neuroscience; GSK-3; Dopamine receptor D2; Synaptic plasticity; Biology; Dopamine; Psychology; Cognition; Receptor; Signal transduction; Cell biology; Genetics","score_opus":0.008519536261669918,"score_gpt":0.26527146624280146,"score_spread":0.25675192998113155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982443853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95171976,0.0006191872,0.04415927,0.00026525828,0.0014070004,0.0007206033,0.0010398463,0.00005585665,0.000013198541],"genre_scores_gemma":[0.9961139,0.00008718948,0.0029771668,0.00010124526,0.00049388246,0.00010756094,0.00002309046,0.00007614709,0.000019837926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977078,0.00013752193,0.00065560406,0.00080403686,0.0002922007,0.00040284247],"domain_scores_gemma":[0.9981198,0.000051910523,0.00027354126,0.0007779317,0.0005894173,0.00018745214],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042687613,0.00038475986,0.00043971196,0.00032507165,0.00006500987,0.000051399336,0.00032601506,0.0005444932,0.00005815842],"category_scores_gemma":[0.0007455774,0.00046408657,0.00016463692,0.0003200655,0.000061938495,0.00001123903,0.0004193107,0.00041493302,0.000027337574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005972849,0.000083556064,0.0043935277,0.00014334354,0.00006795327,0.0000018450094,0.000010483936,0.0100811105,0.98373264,0.00009007074,0.001333876,0.0000018926125],"study_design_scores_gemma":[0.00061085785,0.00010023218,0.17273591,0.0005128036,0.000035275523,6.006989e-8,0.0000053502927,0.0008004116,0.8210605,0.000002683462,0.003633386,0.00050255615],"about_ca_topic_score_codex":0.000028080412,"about_ca_topic_score_gemma":0.000008109671,"teacher_disagreement_score":0.16834238,"about_ca_system_score_codex":0.00016654136,"about_ca_system_score_gemma":0.00038769832,"threshold_uncertainty_score":0.9997811},"labels":[],"label_agreement":null},{"id":"W2982503552","doi":"10.1101/822593","title":"Establishment of an eHAP1 Human Haploid Cell Line Hybrid Reference Genome Assembled from Short and Long Reads","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome British Columbia","funders":"National Institutes of Health; Maryland Advanced Research Computing Center; Johns Hopkins University","keywords":"Reference genome; Computational biology; Genome; Sequence assembly; Biology; Nanopore sequencing; Genetics; Gene; Transcriptome","score_opus":0.012521687819829524,"score_gpt":0.25576970145576056,"score_spread":0.24324801363593104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982503552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891923,0.0037779699,0.0056722388,0.000010784555,0.00031474335,0.0005082476,0.00043971927,0.000060646264,0.00002331788],"genre_scores_gemma":[0.9943368,0.0007364208,0.0042804834,0.000046021305,0.0003838463,0.00005405909,0.000029303377,0.000121261175,0.000011813003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975303,0.0000718687,0.0005471919,0.001167713,0.00026625715,0.0004166955],"domain_scores_gemma":[0.997592,0.000014225559,0.00022413931,0.0016223706,0.0002893326,0.0002579489],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033098506,0.0005292962,0.00057048764,0.00013277518,0.00006839351,0.000111547146,0.0005445646,0.00047876657,0.000023615756],"category_scores_gemma":[0.000033886976,0.0005993985,0.00010352746,0.00009530174,0.000061596045,0.000012344077,0.0007336256,0.00043148152,0.00000485492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029563998,0.00012438765,0.00503819,0.0002812283,0.0001021643,0.000013081887,0.0000047555586,0.0008869467,0.9934849,0.000007697275,0.000023290686,0.0000037540337],"study_design_scores_gemma":[0.00038574656,0.00023584187,0.0736338,0.00011387997,0.000114709925,3.1133062e-8,0.000002725912,0.00028970925,0.9230234,8.508338e-7,0.0015782976,0.00062101457],"about_ca_topic_score_codex":0.00009859422,"about_ca_topic_score_gemma":0.000012624635,"teacher_disagreement_score":0.07046154,"about_ca_system_score_codex":0.000049115977,"about_ca_system_score_gemma":0.00020114606,"threshold_uncertainty_score":0.99964577},"labels":[],"label_agreement":null},{"id":"W2982750119","doi":"10.1093/neuonc/noz175.433","title":"GENE-31. IDENTIFICATION OF CORE AND CONTEXT-SPECIFIC FITNESS GENES IN GLIOBLASTOMA STEM CELLS VIA GENOME-WIDE CRISPR-Cas9 SCREENS","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Context (archaeology); Stem cell; CRISPR; Computational biology; Gene; Genetics; SOX2; Epigenetics; Embryonic stem cell","score_opus":0.012980330572009778,"score_gpt":0.2735275995119839,"score_spread":0.26054726893997415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982750119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908746,0.0036733267,0.004345165,0.00009032684,0.00046533855,0.00043214904,0.000029705123,0.000013170854,0.00007620381],"genre_scores_gemma":[0.998015,0.0013840355,0.00012917498,0.00017777349,0.00010320029,0.000025495003,0.000018853249,0.0000343854,0.000112109454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998557,0.00006956642,0.00047281486,0.00050675997,0.00010982729,0.00028406008],"domain_scores_gemma":[0.9991424,0.00008035371,0.00016105437,0.00042598302,0.00010491879,0.000085281994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019553133,0.00019780667,0.000328212,0.00012299886,0.00003327032,0.000013116706,0.00021220888,0.00024887788,0.000018991792],"category_scores_gemma":[0.000015623045,0.00021461195,0.0000693645,0.00013046412,0.00010172679,0.0000059898853,0.00014511509,0.0001336187,0.000021722824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015434965,0.00005930882,0.007114331,0.00004869629,0.000018513712,0.000015863616,0.00012034918,0.0012613031,0.97567683,0.000014901149,0.00021322722,0.0153022995],"study_design_scores_gemma":[0.0009142208,0.0006678386,0.008945319,0.0000064430233,0.00001408895,0.000052275514,0.00020937248,0.0005179251,0.9432685,0.000011774874,0.04519975,0.00019250697],"about_ca_topic_score_codex":0.000014826539,"about_ca_topic_score_gemma":0.00009594545,"teacher_disagreement_score":0.044986524,"about_ca_system_score_codex":0.00003084788,"about_ca_system_score_gemma":0.00006954532,"threshold_uncertainty_score":0.8751622},"labels":[],"label_agreement":null},{"id":"W2983336726","doi":"10.1139/bcb-2019-0329","title":"Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs)","year":2019,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Lethbridge","funders":"","keywords":"Temozolomide; Cancer research; Stem cell; Biology; Apoptosis; Gene silencing; DNA repair; Cell biology; DNA damage; Programmed cell death; Glioma; Genetics; DNA; Gene","score_opus":0.005733279583275798,"score_gpt":0.23917756210870647,"score_spread":0.23344428252543067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2983336726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996658,0.0017954366,0.000095410476,0.000102600505,0.00018542861,0.00018957893,0.000080981226,0.000023326627,0.00086921005],"genre_scores_gemma":[0.9979347,0.0003422182,0.000097876706,0.0001602022,0.00011745127,0.000012944804,0.00041549208,0.000024669836,0.00089444884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986934,0.000051739116,0.000295868,0.00054914755,0.000057757017,0.00035209526],"domain_scores_gemma":[0.99942535,0.000055630568,0.00008924549,0.0002909561,0.000033777622,0.00010501943],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012598035,0.00025077251,0.0002425489,0.000053545824,0.00003603155,0.000018438092,0.0001660583,0.00044118875,0.000064743486],"category_scores_gemma":[0.000026087839,0.00025024032,0.00006737929,0.00010462447,0.000067218025,0.000004442443,0.00011449952,0.00014423474,0.000024555015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048517388,0.000039679344,0.009141741,0.00011266981,0.000016528376,0.0000011670809,0.00003179929,0.00006173972,0.98952687,0.0000039556426,0.00028893093,0.0007264267],"study_design_scores_gemma":[0.0007545118,0.00016965179,0.0035487097,0.000019582263,0.000008168934,0.0000065273857,0.00010000726,0.00018570152,0.99225444,0.000009898333,0.0026348492,0.000307985],"about_ca_topic_score_codex":0.000012586218,"about_ca_topic_score_gemma":0.0000035319642,"teacher_disagreement_score":0.0055930316,"about_ca_system_score_codex":0.00001954263,"about_ca_system_score_gemma":0.000045515466,"threshold_uncertainty_score":0.999995},"labels":[],"label_agreement":null},{"id":"W2984202283","doi":"10.1038/s41556-019-0415-1","title":"Translational reprogramming marks adaptation to asparagine restriction in cancer","year":2019,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute; U.S. Department of Health and Human Services","keywords":"EIF4E; Reprogramming; MAPK/ERK pathway; Asparagine; mTORC1; Biology; Cancer research; Kinase; Integrated stress response; eIF2; Protein kinase A; Eukaryotic initiation factor; Pancreatic cancer; Translation (biology); Cell biology; PI3K/AKT/mTOR pathway; Cancer; Signal transduction; Genetics; Messenger RNA; Amino acid; Gene","score_opus":0.005681274150609636,"score_gpt":0.31814981239491064,"score_spread":0.312468538244301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984202283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867384,0.00316561,0.0077368715,0.00030639916,0.0005540034,0.00023945798,0.0000098396795,0.000010867861,0.001238577],"genre_scores_gemma":[0.9968982,0.00018112871,0.002032914,0.00019664617,0.00016829013,0.000028031545,0.00019907665,0.000010190751,0.0002855545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993616,0.000022581826,0.000120047545,0.00029202417,0.000042544565,0.00016119915],"domain_scores_gemma":[0.9997594,0.0000100877305,0.000023086945,0.00013913949,0.000033830896,0.000034490084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009400235,0.00008723624,0.00008318083,0.00007436498,0.000012665881,0.0000047236517,0.00007133649,0.00033344532,0.000034923673],"category_scores_gemma":[0.000017250999,0.00008690369,0.00003163916,0.00013606745,0.0000075221237,0.000001629591,0.000017954815,0.00018260392,0.00000927298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008507079,0.000023737637,0.025679024,0.000015364192,0.000008840359,7.4924225e-7,0.00006260027,0.023921834,0.93569916,0.000077106975,0.00022475702,0.01420176],"study_design_scores_gemma":[0.001752636,0.00069479545,0.119346544,0.000035533674,0.000019260144,0.0000053979275,0.00015020363,0.004730557,0.47557148,0.00017812508,0.39691693,0.000598549],"about_ca_topic_score_codex":0.000058272803,"about_ca_topic_score_gemma":0.00017838895,"teacher_disagreement_score":0.46012768,"about_ca_system_score_codex":0.000012231114,"about_ca_system_score_gemma":0.000029211547,"threshold_uncertainty_score":0.35438296},"labels":[],"label_agreement":null},{"id":"W2984255992","doi":"10.1186/s12870-019-2097-z","title":"WheatCRISPR: a web-based guide RNA design tool for CRISPR/Cas9-mediated genome editing in wheat","year":2019,"lang":"en","type":"article","venue":"BMC Plant Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Global Institute for Water Security; University of Saskatchewan; Agriculture and Agri-Food Canada; Plant Biotechnology Institute; National Research Council Canada","funders":"National Research Council Canada","keywords":"CRISPR; Guide RNA; Genome editing; Biology; Cas9; Computational biology; Genome; Gene; Genetics","score_opus":0.0146470907566736,"score_gpt":0.2937210696753137,"score_spread":0.2790739789186401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984255992","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7630792,0.0012501191,0.2328257,0.0001379107,0.00073257415,0.0011149618,0.0004748996,0.00005409575,0.0003305178],"genre_scores_gemma":[0.98068255,0.0001051927,0.016047731,0.0004276491,0.0004921384,0.00017710472,0.0016983526,0.000046233003,0.00032302522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983235,0.00009852312,0.0003993399,0.0005422788,0.00006589953,0.00057047256],"domain_scores_gemma":[0.99925876,0.00018493747,0.00007433668,0.00034924923,0.000054889548,0.000077820034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047093298,0.00025705862,0.0003163017,0.00013193378,0.00004045775,0.000016067659,0.00024258348,0.00034341365,0.0000409171],"category_scores_gemma":[0.00023832795,0.00024406123,0.00011432597,0.00009405539,0.000036763897,0.0000033865413,0.00006644545,0.0001166524,0.00003871165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002333096,0.000034470133,0.011577112,0.00006952577,0.0000228564,0.0000035105627,0.000015368003,0.0041291,0.98125684,0.00002647663,0.0023746563,0.00025677093],"study_design_scores_gemma":[0.006609074,0.0015369024,0.007014621,0.00008033739,0.00004400357,0.000059530576,0.000106720334,0.029888844,0.74522656,0.00006261968,0.20832862,0.0010421583],"about_ca_topic_score_codex":0.00003164341,"about_ca_topic_score_gemma":0.00014264454,"teacher_disagreement_score":0.23603027,"about_ca_system_score_codex":0.0000318884,"about_ca_system_score_gemma":0.00019221303,"threshold_uncertainty_score":0.9952528},"labels":[],"label_agreement":null},{"id":"W2984978709","doi":"10.1038/s41598-019-52543-5","title":"Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Feinstein Institutes for Medical Research; University of Toronto; Government of Canada","keywords":"CRISPR; Interactome; Biology; Computational biology; Bioinformatics; Cell biology; Genetics; Gene","score_opus":0.014793265046540754,"score_gpt":0.30801682374608125,"score_spread":0.2932235586995405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984978709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939016,0.00011772434,0.00089134043,0.00003608541,0.0045208107,0.00033439556,0.000017861448,0.000015529176,0.00016462052],"genre_scores_gemma":[0.99636203,0.00000939326,0.0006801439,0.000040504787,0.000093625174,0.000009088233,0.00009668,0.00003407591,0.0026744837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977129,0.000029851266,0.000622987,0.0008312068,0.00039508188,0.0004079706],"domain_scores_gemma":[0.9986119,0.000018617833,0.00017158485,0.00088052044,0.00015468877,0.0001626863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005489282,0.00022167915,0.0002996564,0.00033709666,0.000048473674,0.00007996251,0.00023093594,0.0001157787,0.000070890565],"category_scores_gemma":[0.00012440945,0.00022416528,0.00013774083,0.0004967053,0.000046600177,0.000012391944,0.00021390499,0.00013859202,0.000034070254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024120607,0.00006243165,0.0023706635,0.00004861671,0.00002390779,0.000056470584,0.0001455431,0.01346795,0.98116356,5.4730924e-7,0.0024120386,0.00022415434],"study_design_scores_gemma":[0.00019397432,0.00014198059,0.009232153,0.000056393717,0.00001899887,0.000035681576,0.0001225944,0.00038976804,0.98486185,0.0000046082578,0.0046972227,0.00024479404],"about_ca_topic_score_codex":0.000095214156,"about_ca_topic_score_gemma":0.000053699972,"teacher_disagreement_score":0.013078182,"about_ca_system_score_codex":0.000036406007,"about_ca_system_score_gemma":0.00011903364,"threshold_uncertainty_score":0.9141195},"labels":[],"label_agreement":null},{"id":"W2985527110","doi":"10.1111/pbi.13296","title":"Genome editing in wheat microspores and haploid embryos mediated by delivery of ZFN proteins and cell‐penetrating peptide complexes","year":2019,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; University of Lethbridge","funders":"Agriculture and Agri-Food Canada; Dow AgroSciences","keywords":"Zinc finger nuclease; Biology; Genome editing; Microspore; Transgene; Genome engineering; Transcription activator-like effector nuclease; Nuclease; Genome; Zinc finger; Genetics; Computational biology; Gene; Cell biology; Botany; Transcription factor","score_opus":0.0035844263150649684,"score_gpt":0.20604736124639386,"score_spread":0.2024629349313289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2985527110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906097,0.008580999,0.00033545346,0.00015388604,0.000053174335,0.00014758042,0.000071011964,0.0000100147845,0.0000381607],"genre_scores_gemma":[0.99557257,0.0027175036,0.001528583,0.000024943978,0.00005095894,0.0000026479738,0.00005951075,0.0000133167505,0.000029944984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991935,0.000019439816,0.00027148594,0.00021009055,0.000068374415,0.00023714891],"domain_scores_gemma":[0.999686,0.000018402341,0.00011439069,0.000106232364,0.000023693186,0.000051276344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001740505,0.00013474327,0.00019157611,0.00012005168,0.00005084913,0.000017981085,0.00011826084,0.00026624033,0.0000074787617],"category_scores_gemma":[0.000028991297,0.00012773006,0.000023695828,0.0000570051,0.000094678006,0.0000051685342,0.00010344099,0.00028587133,8.6142614e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026151756,0.0000181569,0.02123436,0.00004801947,0.000019246792,0.000008811565,0.00004874854,0.00003727474,0.9781603,0.0000039579813,0.00006644079,0.00032848798],"study_design_scores_gemma":[0.00072434294,0.00027620624,0.0127253,0.000058722806,0.000008596066,0.000481637,0.00036535657,0.0002217406,0.9834464,0.000013102767,0.0015228214,0.00015576374],"about_ca_topic_score_codex":0.000027997141,"about_ca_topic_score_gemma":0.000055842072,"teacher_disagreement_score":0.00850906,"about_ca_system_score_codex":0.000007683998,"about_ca_system_score_gemma":0.0000252805,"threshold_uncertainty_score":0.52086806},"labels":[],"label_agreement":null},{"id":"W2986181455","doi":"10.1111/1462-2920.14833","title":"ICETh1 and ICETh2, two interdependent mobile genetic elements in <i>Thermus thermophilus</i> transjugation","year":2019,"lang":"en","type":"article","venue":"Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Centro de Biología Molecular Severo Ochoa; Ministerio de Ciencia, Innovación y Universidades; Fundación Ramón Areces","keywords":"Thermus thermophilus; Biology; Mobile genetic elements; Genetics; Horizontal gene transfer; Computational biology; DNA; Gene; Genome; Escherichia coli; Plasmid","score_opus":0.0015797145134958399,"score_gpt":0.2238810534585896,"score_spread":0.22230133894509377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986181455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968801,0.0017278644,0.0005827312,0.000022429691,0.00014731241,0.00034644833,0.000041550753,0.0000060623424,0.00024549532],"genre_scores_gemma":[0.9986102,0.000337539,0.00039879212,0.00017592128,0.0000542892,0.000027992797,0.00018705713,0.000023903023,0.0001843072],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991104,0.000068513444,0.00020784889,0.00035894534,0.000029290595,0.00022498102],"domain_scores_gemma":[0.9997186,0.0000068058566,0.00003841584,0.00019668028,0.0000015422393,0.000037944563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010604879,0.00015416367,0.00012672895,0.000037181515,0.000019593897,0.0000065695936,0.000112467125,0.00009586443,0.0001644276],"category_scores_gemma":[0.0000013310299,0.00015768435,0.000041019295,0.000020525138,0.000057554593,0.0000026441573,0.000102844824,0.000091432536,0.000051670664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028999537,0.000048551596,0.026584705,0.00000845548,0.00001915061,0.0000023945033,0.00013561817,0.0006524457,0.9666023,0.0000011261353,0.000017747585,0.0058985054],"study_design_scores_gemma":[0.003930409,0.0008402366,0.111794785,0.000024641215,0.000023373572,0.00019221834,0.0004325948,0.00019727251,0.85715425,0.000035587294,0.024812775,0.00056187226],"about_ca_topic_score_codex":0.000010225298,"about_ca_topic_score_gemma":0.000031648353,"teacher_disagreement_score":0.10944806,"about_ca_system_score_codex":0.000025899168,"about_ca_system_score_gemma":0.00000437143,"threshold_uncertainty_score":0.6430181},"labels":[],"label_agreement":null},{"id":"W2986567900","doi":"10.1016/j.scr.2019.101656","title":"Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons","year":2019,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Seventh Framework Programme; Oxford Martin School, University of Oxford; Innovative Medicines Initiative; European Commission; Parkinson's UK; Medical Research Council; Wellcome; European Federation of Pharmaceutical Industries and Associations; Provincia autonoma di Bolzano - Alto Adige; Weston Brain Institute; Wellcome Trust","keywords":"CRISPR; Biology; Gene knockin; Induced pluripotent stem cell; Cas9; Genome editing; Computational biology; Genetics; Molecular biology; Cell biology; Gene; Embryonic stem cell","score_opus":0.02479648719306765,"score_gpt":0.37419464279901415,"score_spread":0.3493981556059465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986567900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99443203,0.0001479334,0.0039213686,0.00008207679,0.00004842994,0.00045971203,0.000013763509,0.0000045011916,0.00089019036],"genre_scores_gemma":[0.9981837,0.000017143104,0.00018605326,0.000021746073,0.00013974225,0.000053031377,0.000040755123,0.00002385498,0.0013339443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987452,0.0000290277,0.00029455902,0.00041377067,0.00020542178,0.0003120028],"domain_scores_gemma":[0.9994074,0.00002480084,0.00003283511,0.00032540812,0.000108005166,0.00010152477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042805233,0.00010632263,0.00014630155,0.00019863978,0.000026024401,0.000038415114,0.0001374568,0.000075803684,0.0000030754284],"category_scores_gemma":[0.000031010357,0.00010924163,0.000022535838,0.00028247669,0.000021219952,0.000004983532,0.00024511374,0.000108850174,0.0000075746207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002161656,0.000049738534,0.012459886,0.00007882386,0.000002722514,0.0000041373646,0.00010531818,0.002050516,0.9834799,0.000016398908,0.00018494189,0.0015459607],"study_design_scores_gemma":[0.00054497644,0.0004997214,0.010044087,0.00003865474,0.000001999043,0.000008486559,0.00033072592,0.0021815333,0.97461736,0.00000645131,0.011536901,0.0001891298],"about_ca_topic_score_codex":0.000076980534,"about_ca_topic_score_gemma":0.000107744825,"teacher_disagreement_score":0.011351959,"about_ca_system_score_codex":0.000015653395,"about_ca_system_score_gemma":0.00002794161,"threshold_uncertainty_score":0.44547442},"labels":[],"label_agreement":null},{"id":"W2986710126","doi":"10.1186/s13024-019-0343-3","title":"Application of CRISPR genetic screens to investigate neurological diseases","year":2019,"lang":"en","type":"review","venue":"Molecular Neurodegeneration","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick; Canada Research Chairs; Discovery Centre; University of Toronto","funders":"Krembil Foundation","keywords":"CRISPR; Genome editing; Cas9; Modular design; Computer science; Disease; Computational biology; Data science; Neuroscience; Risk analysis (engineering); Medicine; Biology; Genetics; Gene","score_opus":0.018720463995069908,"score_gpt":0.3291515109329226,"score_spread":0.31043104693785273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986710126","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031757064,0.76574254,0.22962695,0.000028505548,0.00018954225,0.0010973145,0.00008807228,0.000024335734,0.000027045433],"genre_scores_gemma":[0.011955021,0.9817192,0.0034210563,0.000534993,0.00037597326,0.00031999522,0.0014040727,0.00016685664,0.000102834485],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99791974,0.00018307366,0.0005616409,0.00083243905,0.00023223371,0.00027090352],"domain_scores_gemma":[0.99860203,0.00001409171,0.000196365,0.0009173494,0.00009310824,0.00017704778],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000069315705,0.0004234642,0.00069706957,0.00015302651,0.000038188668,0.0000305999,0.00035984453,0.00030006588,0.000004096731],"category_scores_gemma":[0.00012288721,0.00041067452,0.00036259124,0.00026048202,0.000039026967,0.0000025442778,0.00020382757,0.00014834448,0.000040634437],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025875162,0.000112814065,0.00009535157,0.0044287937,0.00013079673,0.000018130208,0.000009068794,0.038666617,0.22210212,0.0001615532,0.0010456318,0.73320323],"study_design_scores_gemma":[0.0002146643,0.0006639669,0.00028293612,0.000281546,0.0007732494,0.00004234354,8.4542086e-7,0.0018550755,0.04353444,0.000014580193,0.9515904,0.00074593927],"about_ca_topic_score_codex":0.000006488088,"about_ca_topic_score_gemma":0.0000037065097,"teacher_disagreement_score":0.9505448,"about_ca_system_score_codex":0.000009697809,"about_ca_system_score_gemma":0.000108400156,"threshold_uncertainty_score":0.99983454},"labels":[],"label_agreement":null},{"id":"W2987201345","doi":"10.1016/j.celrep.2019.10.017","title":"Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"CRISPR; Genome editing; Cas9; Genome; Computational biology; Biology; Genetics; Gene","score_opus":0.007064573563153331,"score_gpt":0.2653714653455764,"score_spread":0.25830689178242305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987201345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893268,0.0011138379,0.006691263,0.000051754323,0.0009086715,0.00045194392,0.000011001695,0.00002897136,0.0014157646],"genre_scores_gemma":[0.9952477,0.000049849023,0.0010836475,0.00014355338,0.00048124406,0.000027029138,0.00026212324,0.00004822413,0.002656582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865746,0.000011454336,0.00032663633,0.0004952588,0.00011911611,0.0003900777],"domain_scores_gemma":[0.9991851,0.00001080111,0.00013372477,0.00048728116,0.0000806071,0.00010250298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022526889,0.00018812866,0.00020651986,0.000041975378,0.00004755241,0.000027228944,0.000099640514,0.00016992366,0.000028923727],"category_scores_gemma":[0.00004888081,0.0001925539,0.00014289515,0.000047886893,0.000020849604,0.0000037881289,0.00010276318,0.00008462739,0.000015392941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000055409573,0.000031105967,0.0034942091,0.000076826975,0.00002733725,0.00006652687,0.00005497922,0.0011245835,0.99372435,0.0000020811926,0.0012213541,0.00017111577],"study_design_scores_gemma":[0.0003325439,0.00014936645,0.0015556447,0.000010018307,0.000026511569,0.00026036976,0.00006051529,0.00008517486,0.8820709,0.000022704582,0.11517461,0.00025166213],"about_ca_topic_score_codex":0.000010769324,"about_ca_topic_score_gemma":0.0000049849154,"teacher_disagreement_score":0.113953255,"about_ca_system_score_codex":0.0000134594175,"about_ca_system_score_gemma":0.00004594246,"threshold_uncertainty_score":0.785212},"labels":[],"label_agreement":null},{"id":"W2988180713","doi":"10.1101/845446","title":"A genetic map of the response to DNA damage in human cells","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"DNA damage; Biology; CRISPR; DNA; DNA repair; Cell biology; Gene; Genetics","score_opus":0.006419138628990953,"score_gpt":0.24012894468638563,"score_spread":0.23370980605739466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988180713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638283,0.0005475375,0.0012977299,0.000114762785,0.00076965557,0.00076077116,0.00009937571,0.0000221119,0.000005214983],"genre_scores_gemma":[0.9979949,0.000024770054,0.0014665474,0.00011977407,0.00018394546,0.00007453736,1.9184182e-7,0.000090729474,0.0000445833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980826,0.00016716325,0.00044001013,0.0007034003,0.00022070562,0.0003861526],"domain_scores_gemma":[0.9977217,0.000019315683,0.00016649283,0.001826416,0.00014120305,0.0001248789],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047335646,0.00036366895,0.0003519396,0.0001627401,0.00004374099,0.000047354788,0.0007866231,0.00042455003,0.000016599002],"category_scores_gemma":[0.00009583314,0.00035230076,0.00016355592,0.00020988248,0.00006247414,0.0000025581585,0.00097511965,0.00033793217,0.000021188343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007282073,0.00005112441,0.0046729967,0.00020667467,0.000037175385,0.000006142528,0.000011346411,0.006741483,0.98775524,0.00000708503,0.00043753439,3.8074043e-7],"study_design_scores_gemma":[0.00027978138,0.00007244193,0.21845295,0.00015976152,0.000021646436,6.1292575e-9,0.0000026052812,0.00006475812,0.7754948,3.1642222e-7,0.005132148,0.00031880187],"about_ca_topic_score_codex":0.000032667383,"about_ca_topic_score_gemma":0.000013765917,"teacher_disagreement_score":0.21377994,"about_ca_system_score_codex":0.00006217014,"about_ca_system_score_gemma":0.00029180397,"threshold_uncertainty_score":0.9998929},"labels":[],"label_agreement":null},{"id":"W2990517085","doi":"10.1016/j.bbrc.2019.10.007","title":"Highlights for the 60th anniversary of BBRC","year":2019,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Québec Consortium for Drug Discovery; Fondation Brain Canada; Canadian Cancer Society Research Institute; Cancer Research Society; Ontario Centres of Excellence","keywords":"History","score_opus":0.04104087061971304,"score_gpt":0.3945893376020418,"score_spread":0.3535484669823288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990517085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98639905,0.005109393,0.0019918731,0.0046477346,0.00004316044,0.0006256668,0.00005735128,0.00000943417,0.0011163288],"genre_scores_gemma":[0.9968602,0.0014571205,0.0010855702,0.000025987027,0.00007078427,0.0000367726,0.000050856695,0.0000072145267,0.0004055107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942327,0.000035084693,0.00009821622,0.00015514721,0.0001274453,0.00016086352],"domain_scores_gemma":[0.9987452,0.0002694642,0.000017290075,0.00075950427,0.00015222651,0.000056287343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019875857,0.00006150679,0.000080310005,0.000022633092,0.0001067414,0.000011275042,0.00049887,0.00006418377,0.000004676348],"category_scores_gemma":[0.00010629259,0.00004191897,0.000062579435,0.00011662824,0.0003487447,0.0000019879571,0.00036061284,0.000112699774,0.0000050870813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035890076,0.00006207212,0.00005037342,0.00002623721,0.000024792156,2.1382592e-8,0.000019674222,0.000002000792,0.9917922,0.0045009833,0.002276862,0.0012088994],"study_design_scores_gemma":[0.00029496802,0.00023281986,0.0013448542,0.00001678274,0.000011591718,8.9338505e-7,0.00012433296,0.001965999,0.8959892,0.00028883587,0.099641405,0.000088333545],"about_ca_topic_score_codex":0.00001735331,"about_ca_topic_score_gemma":0.000002045143,"teacher_disagreement_score":0.097364545,"about_ca_system_score_codex":0.000004852791,"about_ca_system_score_gemma":0.000030855674,"threshold_uncertainty_score":0.17094061},"labels":[],"label_agreement":null},{"id":"W2990559567","doi":"10.1371/journal.pbio.3000519","title":"Regulation plays a multifaceted role in the retention of gene duplicates","year":2019,"lang":"en","type":"letter","venue":"PLoS Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene duplication; Gene; Genome; Function (biology); Functional divergence; Natural selection; Genetics; Computational biology; Selection (genetic algorithm); Regulation of gene expression; Gene family; Evolutionary biology; Computer science","score_opus":0.012641751947815607,"score_gpt":0.27458184169665256,"score_spread":0.261940089748837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990559567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9478305,0.0035875856,0.0026121493,0.043266006,0.0003598368,0.0012388481,0.00020582008,0.000024032634,0.0008752152],"genre_scores_gemma":[0.97424614,0.00018915637,0.00061183685,0.018342,0.0011147172,0.000086401924,0.0049859025,0.000040582836,0.0003832851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990164,0.0001062765,0.00025579784,0.00034143619,0.000070837414,0.00020927073],"domain_scores_gemma":[0.9993112,0.000039406827,0.00012140826,0.0004728759,0.000047121208,0.000007955196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012958318,0.00016803948,0.00022073177,0.00007694137,0.000015154402,0.000005310783,0.00026924346,0.0007726578,0.000015471562],"category_scores_gemma":[0.000058937414,0.00012940085,0.00009214026,0.000070937764,0.000049539263,9.660839e-7,0.00004879238,0.000299224,0.000012007022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017012651,0.000018837905,0.00097643683,0.000058675796,0.00004812485,0.0000011950398,0.00005253292,0.00014054074,0.97653687,0.0000042895276,0.021928497,0.00021697477],"study_design_scores_gemma":[0.0006087954,0.00038117415,0.00770951,0.000047232585,0.000068437075,0.000020529476,0.000045883542,0.0014171684,0.75734794,0.00013593685,0.23185489,0.0003624821],"about_ca_topic_score_codex":0.000027512911,"about_ca_topic_score_gemma":0.000008836826,"teacher_disagreement_score":0.21918891,"about_ca_system_score_codex":0.000008601452,"about_ca_system_score_gemma":0.000020475885,"threshold_uncertainty_score":0.59594446},"labels":[],"label_agreement":null},{"id":"W2991193264","doi":"10.1038/s41467-019-13403-y","title":"CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"CRISPR; Genome editing; Cas9; Subgenomic mRNA; Guide RNA; Biology; Computational biology; Homologous recombination; Genetics; Gene","score_opus":0.01015169466143732,"score_gpt":0.3447118946815685,"score_spread":0.33456020002013115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991193264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9674654,0.0060831592,0.02177516,0.001612599,0.0004331828,0.0006144654,0.00013686527,0.000030504645,0.0018486422],"genre_scores_gemma":[0.9933947,0.00019249479,0.005280536,0.000046263533,0.00008353362,0.000029301984,0.0006145984,0.00001750017,0.000341112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947137,0.000037206926,0.00013807653,0.0001604877,0.00007374246,0.0001191342],"domain_scores_gemma":[0.9988327,0.000048677528,0.00009349338,0.0008244555,0.00017310993,0.00002755016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017330704,0.000089724475,0.000105975916,0.000029858775,0.00007805684,0.000012179417,0.00039041202,0.0002042555,0.000008620077],"category_scores_gemma":[0.000101471276,0.00009737414,0.00007807491,0.00007693468,0.0000343965,0.000005943798,0.00015492969,0.00021446486,0.0000015725104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000134892125,0.00005825825,0.00082403905,0.000026705133,0.00003506207,1.30097515e-8,0.000031219028,0.00012649593,0.98807263,0.0007203176,0.007535505,0.0025562358],"study_design_scores_gemma":[0.00059730245,0.000074455624,0.0012942901,0.000017318269,0.000025779626,0.000002015223,0.00004489938,0.0026254104,0.93787456,0.00019285639,0.057117343,0.00013374767],"about_ca_topic_score_codex":0.000014832403,"about_ca_topic_score_gemma":0.00006483734,"teacher_disagreement_score":0.05019808,"about_ca_system_score_codex":0.00001452768,"about_ca_system_score_gemma":0.000026272735,"threshold_uncertainty_score":0.3970802},"labels":[],"label_agreement":null},{"id":"W2991321019","doi":"10.1101/851683","title":"A saturating mutagenesis CRISPR-Cas9 mediated functional genomic screen identifies <i>cis-</i> and <i>trans-</i> regulatory elements of <i>Oct4</i> in murine ESCs","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Health and Medical Research Council; Medical Research Council; Monash University; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Enhancer; Biology; Gene; Genetics; Promoter; Cas9; Regulatory sequence; Genome; Mutagenesis; Regulation of gene expression; Transcription factor; Computational biology; Gene expression; Mutation","score_opus":0.007388447373986664,"score_gpt":0.2243297382310692,"score_spread":0.21694129085708252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991321019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842207,0.008067691,0.0058085164,0.000037688347,0.00068838976,0.00069251866,0.0004177671,0.000055166616,0.000011599243],"genre_scores_gemma":[0.99578106,0.0014382644,0.0020748142,0.00013323146,0.00032427575,0.00008295326,0.000014804654,0.00013477942,0.000015786409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969848,0.00010630509,0.00090848637,0.0010976475,0.00037587827,0.0005269042],"domain_scores_gemma":[0.99809015,0.00004233894,0.0003924706,0.0010332634,0.0002627918,0.00017899257],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006586703,0.00059569546,0.0006442821,0.00026214958,0.00007368147,0.000076201635,0.00038467927,0.00061213906,0.00002043947],"category_scores_gemma":[0.00011813265,0.00069537887,0.00017607101,0.0002551032,0.00013088851,0.000015612706,0.0005925566,0.0004415579,0.00000590205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000099578596,0.00006919165,0.021525066,0.00059880293,0.00019589264,0.000010934019,0.000011469483,0.0015733003,0.9756667,0.000010571743,0.00023227869,0.000006237455],"study_design_scores_gemma":[0.0011119852,0.00008029994,0.2035409,0.00027285164,0.000107308566,1.2341764e-7,0.000008190479,0.00044613623,0.79204595,9.38852e-7,0.0017023708,0.0006829188],"about_ca_topic_score_codex":0.000078826735,"about_ca_topic_score_gemma":0.00003148175,"teacher_disagreement_score":0.1836207,"about_ca_system_score_codex":0.00006944746,"about_ca_system_score_gemma":0.00031861072,"threshold_uncertainty_score":0.99954975},"labels":[],"label_agreement":null},{"id":"W2992464475","doi":"","title":"MORGEN & Data Release Policies: An Overview","year":2007,"lang":"en","type":"article","venue":"Health law review","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Commercialization; Science policy; Computer science; Political science; Public administration; Law","score_opus":0.09008845433044926,"score_gpt":0.47213445308555374,"score_spread":0.3820459987551045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992464475","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021102051,0.9905719,0.00381064,0.0014633391,0.00014326075,0.0004561295,0.000058688838,0.000028402601,0.0013573986],"genre_scores_gemma":[0.042870697,0.90853745,0.002923235,0.04375834,0.0005366487,0.000012296118,0.001152368,0.00004486056,0.0001641161],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987833,0.000052377785,0.00036490243,0.00033916565,0.00011102463,0.00034925714],"domain_scores_gemma":[0.99835163,0.000007116554,0.0000740814,0.0012563923,0.000032908076,0.0002778849],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001040203,0.00013052968,0.00023312437,0.00001218789,0.00007259071,0.000008398533,0.0003538512,0.00005319269,0.00003997558],"category_scores_gemma":[0.00005263259,0.00012034811,0.00004631657,0.00010024709,0.000025346466,0.000004398961,0.00015613707,0.00007530861,0.000025047477],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005521343,0.0004996314,0.00043458104,0.039602596,0.00013823628,0.00003006362,0.0001269738,0.000051536124,0.013700165,0.032048192,0.19860378,0.71470904],"study_design_scores_gemma":[0.0000944896,0.000109878965,0.0004187907,0.00061544025,0.000013865402,0.000025697387,0.000005088324,0.000015810803,0.00073912996,0.000012250585,0.9978175,0.0001320597],"about_ca_topic_score_codex":0.0004446681,"about_ca_topic_score_gemma":0.0007796694,"teacher_disagreement_score":0.7992137,"about_ca_system_score_codex":0.000013300053,"about_ca_system_score_gemma":0.000089867885,"threshold_uncertainty_score":0.49076533},"labels":[],"label_agreement":null},{"id":"W2995081665","doi":"10.1038/s41579-019-0299-x","title":"Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants","year":2019,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2464,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université Laval","funders":"National Institute of General Medical Sciences","keywords":"Biology; CRISPR; Class (philosophy); Computational biology; Genetics; Evolutionary biology; Gene; Computer science; Artificial intelligence","score_opus":0.02517715991784872,"score_gpt":0.3543327043941358,"score_spread":0.32915554447628703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995081665","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012466444,0.99660695,0.0010587032,0.0000062861723,0.00057397014,0.0012207611,0.00032359804,0.000005349701,0.00007973448],"genre_scores_gemma":[0.0018216899,0.99599844,0.00050602044,0.000016045646,0.00016441259,0.0000607124,0.0012879183,0.000039544317,0.00010520206],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99783766,0.00034018158,0.0009833,0.00056592544,0.000045394798,0.00022752702],"domain_scores_gemma":[0.99830276,0.000055985158,0.00080511876,0.00066209305,0.00012623366,0.00004780687],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00036120196,0.00038482138,0.0019695198,0.00013836999,0.00001864197,0.0000048990114,0.0003158693,0.00164196,0.000006311898],"category_scores_gemma":[0.00013730567,0.00031470033,0.0004005109,0.00016250518,0.00012497534,0.0000023598789,0.0001564,0.0004434845,0.000009481466],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035509478,0.00011901433,0.00004508794,0.11145055,0.00078400684,0.0000033116462,0.000029110312,0.000008245244,0.4857336,0.0004944929,0.0062663346,0.39503074],"study_design_scores_gemma":[0.00016609754,0.00012407961,0.00008605357,0.004735023,0.0005184818,0.00026667802,0.0000063455554,0.0000040205564,0.0005679848,0.0000014421801,0.9932586,0.0002652259],"about_ca_topic_score_codex":0.000004681951,"about_ca_topic_score_gemma":0.0000026976497,"teacher_disagreement_score":0.98699224,"about_ca_system_score_codex":0.000030451813,"about_ca_system_score_gemma":0.00016219575,"threshold_uncertainty_score":0.9999305},"labels":[],"label_agreement":null},{"id":"W2996715978","doi":"10.1021/acssynbio.9b00456","title":"A Bifunctional Polyphosphate Kinase Driving the Regeneration of Nucleoside Triphosphate and Reconstituted Cell-Free Protein Synthesis","year":2019,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science; Natural Sciences and Engineering Research Council of Canada; Genome Canada; National Science Foundation","keywords":"Nucleoside-diphosphate kinase; Biochemistry; Kinase; GTP'; Polyphosphate; Cell-free protein synthesis; Nucleoside triphosphate; Protein kinase A; Phosphofructokinase 2; Nucleoside; Biology; Protein biosynthesis; Chemistry; Cell biology; Enzyme; Nucleotide; Phosphate; Gene","score_opus":0.004760066890453769,"score_gpt":0.2350407151799278,"score_spread":0.23028064828947403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2996715978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927614,0.0024940604,0.0030158048,0.00048527017,0.0002497584,0.00035209183,0.000023075188,0.00001329987,0.0006052595],"genre_scores_gemma":[0.99811155,0.00026224743,0.001028282,0.000056946214,0.00007015944,0.000058392925,0.000018021792,0.0000181456,0.0003762491],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990716,0.00007547089,0.00024494907,0.0003323555,0.0000628966,0.00021270788],"domain_scores_gemma":[0.999227,0.00006647634,0.00010396283,0.00050314947,0.000052145675,0.00004727965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025814152,0.00015733425,0.00018130665,0.00004334735,0.000070681555,0.000012673159,0.00021088735,0.00016958262,0.000061700484],"category_scores_gemma":[0.00021337646,0.00011950017,0.00006168665,0.000075744865,0.00016471399,0.0000040295577,0.00014372639,0.000082217615,0.000008922234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005067652,0.00002476906,0.001784893,0.000026778023,0.000038647522,4.822763e-7,0.000020911633,0.00014430506,0.99154997,0.0008895755,0.00011426999,0.0053547095],"study_design_scores_gemma":[0.00035908003,0.00016865483,0.0014189109,0.000034687222,0.000030547842,0.0000192136,0.000044038687,0.00027668517,0.99177426,0.0002623444,0.005455423,0.00015615574],"about_ca_topic_score_codex":0.00004618324,"about_ca_topic_score_gemma":0.000023165032,"teacher_disagreement_score":0.005350176,"about_ca_system_score_codex":0.000007508608,"about_ca_system_score_gemma":0.00004781904,"threshold_uncertainty_score":0.48730755},"labels":[],"label_agreement":null},{"id":"W2997388470","doi":"10.1101/gr.255414.119","title":"Versatile and robust genome editing with <i>Streptococcus thermophilus</i> CRISPR1-Cas9","year":2020,"lang":"en","type":"article","venue":"Genome Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec; Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire de Sherbrooke; Centre hospitalier universitaire de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Fondation du Grand défi Pierre Lavoie; National Institutes of Health; Agence Nationale de la Recherche; University of California, San Francisco; National Institute of General Medical Sciences; Banting Research Foundation","keywords":"Biology; CRISPR; Cas9; Genome editing; Computational biology; Streptococcus thermophilus; Genetics; Genome; Cytosine; DNA; Gene; Bacteria","score_opus":0.04119857332022864,"score_gpt":0.3296058049842609,"score_spread":0.28840723166403226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997388470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9750019,0.004650126,0.011144683,0.0017803536,0.000052696843,0.00068164396,0.000058076203,0.000045110355,0.006585441],"genre_scores_gemma":[0.9972315,0.00040974727,0.0009941687,0.00015195948,0.00089607586,0.000043280048,0.0000645793,0.000044475284,0.00016422075],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99852663,0.00005952946,0.00014166991,0.0004799083,0.00029213808,0.00050014246],"domain_scores_gemma":[0.999282,0.000021531467,0.000023664534,0.00028317605,0.00012617871,0.0002634392],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003127022,0.00015407377,0.0001411733,0.00005941362,0.00015955475,0.00006469402,0.00022477252,0.00009641423,0.0000774613],"category_scores_gemma":[0.00007130543,0.00013822023,0.000035936755,0.00023177158,0.00013230181,0.000004386036,0.0002880798,0.00026110787,0.000029636807],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008295918,0.000018143555,0.0010606775,0.00009290084,0.00006216231,0.000028687675,0.0005237383,0.0036212874,0.9924209,0.000013384971,0.00056472863,0.0015104287],"study_design_scores_gemma":[0.0042586755,0.004830587,0.04100801,0.00007410108,0.00007477228,0.00013253787,0.005440957,0.0028820888,0.408442,0.00006249249,0.53111225,0.0016815099],"about_ca_topic_score_codex":0.000017786077,"about_ca_topic_score_gemma":0.000011173572,"teacher_disagreement_score":0.5839789,"about_ca_system_score_codex":0.000015280277,"about_ca_system_score_gemma":0.000067593406,"threshold_uncertainty_score":0.5636458},"labels":[],"label_agreement":null},{"id":"W2997444844","doi":"10.20944/preprints201912.0385.v1","title":"Genome Editing for the Understanding and Treatment of Cardiomyopathies","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"","keywords":"Transcription activator-like effector nuclease; Genome editing; Zinc finger nuclease; CRISPR; Cardiomyopathy; Duchenne muscular dystrophy; Genome; Biology; Computational biology; Muscle disease; Genome engineering; Genetics; Medicine; Disease; Heart failure; Internal medicine; Gene","score_opus":0.10105741056733897,"score_gpt":0.3542359872427503,"score_spread":0.2531785766754113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997444844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500896,0.004705155,0.043032672,0.00010392373,0.00054989033,0.00083273003,0.00006749951,0.000012754743,0.0006057784],"genre_scores_gemma":[0.9966905,0.002135483,0.00019138672,0.000008033619,0.00048640423,0.0001185744,0.0000598524,0.000028272292,0.0002814636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908686,0.000020889918,0.00020780285,0.00042674603,0.000081301034,0.00017642557],"domain_scores_gemma":[0.9991519,0.000046031073,0.00010945441,0.0006117652,0.000045349272,0.000035506015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022549747,0.00019649105,0.00025183565,0.00003562127,0.00006148004,0.000010426358,0.000164636,0.00017483786,0.000007680275],"category_scores_gemma":[0.000057137164,0.00015791293,0.00017834897,0.000021319216,0.00006301653,0.0000010693263,0.00045958193,0.000081369864,0.0000026359978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107555636,0.00005877623,0.18668084,0.00064749666,0.0010717039,0.0000014031145,0.0013438067,0.041169327,0.76759034,0.00020914999,0.00001815868,0.0011014307],"study_design_scores_gemma":[0.0013774792,0.00033603923,0.18210238,0.00014806664,0.00048943196,0.000018999166,0.0019831045,0.0014771764,0.78136533,0.0006434089,0.02937962,0.00067895727],"about_ca_topic_score_codex":0.000027907614,"about_ca_topic_score_gemma":0.000009097665,"teacher_disagreement_score":0.046600934,"about_ca_system_score_codex":0.000046377107,"about_ca_system_score_gemma":0.000047737787,"threshold_uncertainty_score":0.6439502},"labels":[],"label_agreement":null},{"id":"W2998455966","doi":"10.1016/j.omtn.2019.12.021","title":"A Universal Surrogate Reporter for Efficient Enrichment of CRISPR/Cas9-Mediated Homology-Directed Repair in Mammalian Cells","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Major Science and Technology Projects of China; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Genome editing; Homology directed repair; Computational biology; Biology; Trans-activating crRNA; DNA; Genetics; DNA repair; Gene; Nucleotide excision repair","score_opus":0.0050329950211648565,"score_gpt":0.24870616540013565,"score_spread":0.2436731703789708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2998455966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910418,0.0010228237,0.006510854,0.000073265066,0.0002843952,0.0007712344,0.000040853705,0.00005575614,0.00019904142],"genre_scores_gemma":[0.9966749,0.00010663641,0.002445447,0.00019070719,0.000029805833,0.000036254325,0.00011552264,0.000055660807,0.00034509617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984881,0.00007248385,0.00038754955,0.0005123178,0.00015977875,0.00037973147],"domain_scores_gemma":[0.9990838,0.00001946326,0.00012209277,0.00059187826,0.00010244627,0.00008029645],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028506908,0.00024202911,0.0003018387,0.00012796876,0.000023722698,0.0000069182183,0.00020464371,0.0002222987,0.00005159941],"category_scores_gemma":[0.00002701401,0.0002454158,0.00024584023,0.00019581329,0.000057109337,0.0000025418274,0.00007019733,0.000089683504,0.000008654465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032055238,0.00015313832,0.0021750827,0.000039970793,0.00011539638,0.000036319034,0.00015478517,0.0035189479,0.9926466,0.000024632556,0.00033434632,0.00048026466],"study_design_scores_gemma":[0.0027616776,0.00080848613,0.004733875,0.000021430265,0.000020878702,0.000015649268,0.00011267426,0.0029145137,0.96556866,0.0000139282165,0.022701418,0.0003267853],"about_ca_topic_score_codex":0.000040898027,"about_ca_topic_score_gemma":0.000010367253,"teacher_disagreement_score":0.02707788,"about_ca_system_score_codex":0.000033672102,"about_ca_system_score_gemma":0.00005821984,"threshold_uncertainty_score":0.9999998},"labels":[],"label_agreement":null},{"id":"W2998900799","doi":"10.29173/hsi228","title":"An Overview of CRISPR – From Germs to Giants","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Biology; Genetics","score_opus":0.1250713339338267,"score_gpt":0.5039428773900322,"score_spread":0.3788715434562055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2998900799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900948,0.0014060569,0.0071505173,0.0004133809,0.0006608526,0.00012397843,0.000014403821,0.000006756887,0.00012928568],"genre_scores_gemma":[0.9954636,0.00037271032,0.0032276704,0.0006532512,0.00024527402,0.0000051707752,0.0000063312527,0.0000075251637,0.00001848654],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990055,0.00000806539,0.00017497622,0.00033707448,0.00018575405,0.00028864047],"domain_scores_gemma":[0.99864477,0.000002541363,0.00009052104,0.0009276494,0.00006380894,0.00027071612],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003595226,0.00007980583,0.00012419134,0.00004287952,0.00026129093,0.000047031746,0.00066399394,0.000040430394,0.00001322252],"category_scores_gemma":[0.000076296805,0.00007547622,0.000026580114,0.00006841052,0.0002587276,0.000011352939,0.00016426433,0.000039717404,0.000008928396],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027558497,0.00005007878,0.00939504,0.00005372351,0.000004227453,0.0000012550051,0.00075640145,0.00028457725,0.94731617,0.000102780774,0.0011892373,0.040818933],"study_design_scores_gemma":[0.00022375933,0.00054867147,0.5534768,0.00007169385,0.0000024986828,0.000003190857,0.00020601113,0.00033352367,0.43819216,0.00007941589,0.0066847377,0.00017749985],"about_ca_topic_score_codex":0.00033836105,"about_ca_topic_score_gemma":0.00007030531,"teacher_disagreement_score":0.5440818,"about_ca_system_score_codex":0.000012485038,"about_ca_system_score_gemma":0.00022897685,"threshold_uncertainty_score":0.3077831},"labels":[],"label_agreement":null},{"id":"W2998955300","doi":"10.29173/hsi233","title":"CRISPR and TALEN: Facilitating Tailored Genomes of the Future","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Transcription activator-like effector nuclease; Genome editing; Computational biology; Genome; Biology; Computer science; Genetics; Gene","score_opus":0.026312640698383814,"score_gpt":0.38308554374576365,"score_spread":0.35677290304737985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2998955300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937874,0.0034360578,0.00088382704,0.0010108975,0.00062848703,0.00011211168,0.0000040847617,0.0000033209176,0.0001337889],"genre_scores_gemma":[0.99814564,0.00036650273,0.0010255412,0.00016555506,0.00023160224,0.000003581254,8.8085665e-7,0.000003845523,0.000056857356],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993114,0.000008442701,0.00012801921,0.00020767885,0.00013667888,0.00020776673],"domain_scores_gemma":[0.99929166,0.0000036864692,0.00009956996,0.00047977007,0.000046766687,0.00007856652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038137299,0.00006362399,0.000078819714,0.000020260664,0.00055212487,0.000034181565,0.00037151328,0.000036687987,0.0000018827413],"category_scores_gemma":[0.00007479836,0.00004610079,0.000024561092,0.000048720973,0.0007446149,0.0000065571794,0.00023933897,0.000057430956,5.0974796e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001883568,0.000027576913,0.07106415,0.00030416978,0.000010399622,7.0012624e-7,0.0045073894,0.00031477556,0.7838933,0.00037538065,0.0015419541,0.13794139],"study_design_scores_gemma":[0.00035661703,0.0002479646,0.8266479,0.000054117532,0.0000041436815,0.000022438502,0.004661487,0.0006049675,0.1509913,0.000112838934,0.016090425,0.00020581814],"about_ca_topic_score_codex":0.000020323188,"about_ca_topic_score_gemma":0.000023139435,"teacher_disagreement_score":0.7555837,"about_ca_system_score_codex":0.0000073326673,"about_ca_system_score_gemma":0.00016141949,"threshold_uncertainty_score":0.42465538},"labels":[],"label_agreement":null},{"id":"W2999234005","doi":"10.29173/hsi239","title":"Query into the Future of Gene Editing: Possibilities and Apprehensions","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Ted Rogers Centre for Heart Research; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Computer science; Genome editing; Information retrieval; Computational biology; Data science; Gene; World Wide Web; Biology; Genetics; Genome","score_opus":0.027147224063131702,"score_gpt":0.3825576610390751,"score_spread":0.35541043697594343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999234005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910105,0.0051493812,0.0008948317,0.0019310645,0.00083506596,0.00009266227,0.0000018489771,0.000004411044,0.00008024956],"genre_scores_gemma":[0.99653435,0.0006652307,0.0017043508,0.00023891527,0.0008092162,0.0000048656493,0.0000019526142,0.000004416826,0.000036685764],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99931633,0.000009025822,0.00013410524,0.00021468938,0.00012963079,0.00019618668],"domain_scores_gemma":[0.9992186,0.000006611112,0.00008730169,0.0005354812,0.000061764615,0.00009028632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004881217,0.00006421161,0.00008012484,0.000025338684,0.0006715965,0.000041615247,0.00031502216,0.000037935537,0.0000013743312],"category_scores_gemma":[0.00007442836,0.00004516687,0.000021142389,0.000041806314,0.0010755186,0.0000070824804,0.00017704582,0.000058246693,4.164544e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026618596,0.000047401205,0.029614223,0.00027078815,0.00001392808,0.0000015398641,0.013188589,0.00022483681,0.8464574,0.0016198952,0.003343184,0.1051916],"study_design_scores_gemma":[0.00047794252,0.00053483155,0.5748875,0.000096449985,0.000009360457,0.00006490332,0.018977562,0.0007643127,0.37392196,0.00080086314,0.02913063,0.00033368779],"about_ca_topic_score_codex":0.00008739651,"about_ca_topic_score_gemma":0.00006137089,"teacher_disagreement_score":0.5452733,"about_ca_system_score_codex":0.0000065816153,"about_ca_system_score_gemma":0.00019381427,"threshold_uncertainty_score":0.5165445},"labels":[],"label_agreement":null},{"id":"W2999616463","doi":"10.29173/hsi230","title":"CRISPRs to Treat, Understand, and Prevent Disease","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Disease; Medicine; Intensive care medicine; Biology; Internal medicine","score_opus":0.0528171012939696,"score_gpt":0.4403486764562257,"score_spread":0.3875315751622561,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999616463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98601884,0.0008801303,0.009469406,0.0027868513,0.0003439179,0.0002057482,0.000005233181,0.00000860301,0.0002812556],"genre_scores_gemma":[0.99806076,0.0002442529,0.0006540777,0.000639796,0.0001629757,0.000008689303,0.0000020569944,0.000006558691,0.00022081773],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99913484,0.0000055460155,0.00009974579,0.00032966136,0.00013541707,0.0002947624],"domain_scores_gemma":[0.9989348,0.0000022340369,0.000038038248,0.0004993202,0.000026946596,0.0004986493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028478095,0.00007872259,0.00007200888,0.00003996647,0.00053184846,0.000089202105,0.00025571644,0.000021018172,0.0000031192208],"category_scores_gemma":[0.000091067806,0.00007288861,0.00001769017,0.000042935233,0.0003140386,0.0000070455008,0.00019347828,0.00003226695,0.000004086179],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049604295,0.0004802592,0.1252923,0.0011227358,0.000031432697,0.000043998836,0.007590678,0.003020045,0.5495687,0.0034875087,0.04584191,0.26302436],"study_design_scores_gemma":[0.0008723075,0.0009639982,0.87931585,0.00013865203,0.00001443158,0.000025467521,0.001415345,0.00062303705,0.08945767,0.0004725778,0.02605346,0.0006471747],"about_ca_topic_score_codex":0.00003486088,"about_ca_topic_score_gemma":0.000024727284,"teacher_disagreement_score":0.75402355,"about_ca_system_score_codex":0.000024508896,"about_ca_system_score_gemma":0.0002441323,"threshold_uncertainty_score":0.40906018},"labels":[],"label_agreement":null},{"id":"W3000155195","doi":"10.1038/s41596-019-0238-3","title":"Manipulating gene translation in plants by CRISPR–Cas9-mediated genome editing of upstream open reading frames","year":2020,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Biology; Cas9; Genome editing; Transgene; Gene; Translation (biology); Mutant; Open reading frame; Guide RNA; Genetics; Computational biology; Upstream open reading frame; Messenger RNA","score_opus":0.020891704606806435,"score_gpt":0.35319325547725083,"score_spread":0.3323015508704444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000155195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88334405,0.0024934553,0.029681077,0.00089844345,0.00015912179,0.07990897,0.0004379361,0.00008524846,0.0029917243],"genre_scores_gemma":[0.9902652,0.0000122744,0.004656163,0.00020075345,0.00023097236,0.004248741,0.0003443351,0.00002963295,0.000011931987],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990023,0.00003490676,0.00030994546,0.00031427172,0.00013081537,0.00020779092],"domain_scores_gemma":[0.9996112,0.000022608181,0.000105662715,0.00015476845,0.00003489552,0.00007084914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016624389,0.00015025582,0.00020473117,0.00003409682,0.000030688894,0.000031262633,0.00028479044,0.00033146408,0.0000128984775],"category_scores_gemma":[0.00014486643,0.0001537944,0.000041382857,0.00012513647,0.000013653765,0.000008715143,0.000094860006,0.00029399546,0.0000014355558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009461833,0.0000264244,0.0047456785,0.000101918675,0.00001914571,0.0000035081962,0.00022754645,0.0008477646,0.99116915,0.000004309101,0.0002656315,0.002494299],"study_design_scores_gemma":[0.0011027671,0.00020407916,0.0021273715,0.00010541823,0.000005870582,0.0000044413428,0.00011048751,0.0016445069,0.9843786,0.00001666243,0.010090111,0.00020969762],"about_ca_topic_score_codex":0.000017856206,"about_ca_topic_score_gemma":0.000011079899,"teacher_disagreement_score":0.10692117,"about_ca_system_score_codex":0.000009780932,"about_ca_system_score_gemma":0.00002721142,"threshold_uncertainty_score":0.6271554},"labels":[],"label_agreement":null},{"id":"W3000262573","doi":"10.1038/s41587-019-0393-7","title":"Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors","year":2020,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":424,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Mutagenesis; Saturated mutagenesis; Biology; Gene; DNA shuffling; CRISPR; Genetics; Cytosine; Cas9; Directed evolution; Computational biology; Mutant","score_opus":0.002801744524512381,"score_gpt":0.21751821114113223,"score_spread":0.21471646661661986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000262573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9663374,0.02033731,0.008389135,0.00406983,0.00036670946,0.00023309264,0.00017034114,0.000071626826,0.000024548535],"genre_scores_gemma":[0.9944946,0.0007174024,0.0036422992,0.00018612061,0.00080558076,0.0000078418925,0.000104259954,0.000022796014,0.0000190538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923956,0.000013263148,0.00014489451,0.00033555567,0.00009123664,0.000175468],"domain_scores_gemma":[0.99962026,0.0000113362885,0.000053485313,0.0002042299,0.000039907023,0.00007080715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047949106,0.0001633303,0.00021696101,0.000061850515,0.000027582,0.000004508379,0.000118412965,0.00075409346,0.000009329328],"category_scores_gemma":[0.00008604562,0.00013172488,0.00003781851,0.00014963823,0.0001260827,0.0000017467107,0.000105576386,0.00024729865,7.714569e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037562777,0.000015227108,0.00041427743,0.000043543176,0.00007150277,0.000021634056,0.000015841477,0.000117059615,0.9948974,0.000040648123,0.0024898765,0.0014973232],"study_design_scores_gemma":[0.0013085573,0.0005362204,0.00033459996,0.000008605086,0.00003559726,0.00008415091,0.000045047716,0.00016877182,0.93750656,0.0000027190706,0.059815224,0.00015395836],"about_ca_topic_score_codex":0.0000043892423,"about_ca_topic_score_gemma":0.0000077842005,"teacher_disagreement_score":0.05739089,"about_ca_system_score_codex":0.0000026509729,"about_ca_system_score_gemma":0.000026216372,"threshold_uncertainty_score":0.58162594},"labels":[],"label_agreement":null},{"id":"W3000472092","doi":"10.29173/hsi238","title":"It’s In Your Genes: Recent Considerations in Germline versus Somatic Gene Therapy","year":2017,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Germline; Somatic cell; Gene; Genetics; Biology; Genetic enhancement; Germline mutation; Mutation","score_opus":0.15446218859090505,"score_gpt":0.47028417885606616,"score_spread":0.3158219902651611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000472092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989954,0.0023485133,0.0006445597,0.005601338,0.0009988081,0.0002543804,0.0000024973253,0.0000069465486,0.00018895259],"genre_scores_gemma":[0.9932027,0.0037938256,0.001975083,0.00079765293,0.0001697573,0.000027409686,0.000006882514,0.000008422172,0.000018252273],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99882305,0.000018603469,0.00028530465,0.0003316123,0.00015940994,0.00038199977],"domain_scores_gemma":[0.9991859,0.000010822472,0.00008781249,0.0005472409,0.000051486102,0.00011672476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067643786,0.00010150328,0.00012932916,0.00010674318,0.00029208141,0.000071844595,0.00027045715,0.00005603731,0.000016062102],"category_scores_gemma":[0.00019673667,0.00009970339,0.000021174654,0.0001134403,0.0002713974,0.0000124975195,0.00009328342,0.000082100894,0.000004579347],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015301889,0.0003502366,0.05277323,0.00008847329,0.000014396857,0.000033246764,0.004976085,0.008016512,0.86063325,0.00030824705,0.0018789626,0.07077433],"study_design_scores_gemma":[0.006000176,0.00088559586,0.65141076,0.000116990625,0.0000032904877,0.000052291747,0.0016390563,0.004449361,0.30966288,0.00031577176,0.02474569,0.0007181293],"about_ca_topic_score_codex":0.000092199436,"about_ca_topic_score_gemma":0.0006862893,"teacher_disagreement_score":0.5986375,"about_ca_system_score_codex":0.00005745912,"about_ca_system_score_gemma":0.00063111814,"threshold_uncertainty_score":0.40657863},"labels":[],"label_agreement":null},{"id":"W3000630567","doi":"10.29173/hsi3","title":"The Need for Ethical and Experimental Regulation in Genome Editing","year":2019,"lang":"en","type":"article","venue":"Health Science Inquiry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Genome editing; Computational biology; Genome; Biology; Genetics; Gene","score_opus":0.024753000470179337,"score_gpt":0.3974308481062933,"score_spread":0.372677847636114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000630567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947829,0.0008409549,0.0023906692,0.0013179242,0.00037878111,0.00023760427,5.741748e-7,0.0000035035555,0.00004703822],"genre_scores_gemma":[0.99853426,0.000030417668,0.00067255594,0.00050932064,0.00019867429,0.000015825,0.0000036959445,0.000003894965,0.000031336283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941254,0.000007570579,0.00011022024,0.00017570183,0.00008642021,0.00020754136],"domain_scores_gemma":[0.99977875,0.000013592157,0.00002539199,0.00011132129,0.000019577737,0.000051355677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007321704,0.000041387888,0.00004567904,0.000024666502,0.00014333312,0.00002395146,0.000082809565,0.00004792608,0.0000011269422],"category_scores_gemma":[0.0000397084,0.000033237804,0.000010227839,0.000075406526,0.0001513516,0.0000030898336,0.000051147075,0.00006100984,8.3361545e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021147946,0.0000069014636,0.0019512994,0.00002369821,8.1877596e-7,5.6010993e-8,0.00078430754,0.0008426312,0.9932819,0.0005134987,0.00017154348,0.0024021994],"study_design_scores_gemma":[0.0020305573,0.0014187696,0.29542613,0.00007448318,0.0000020881132,0.000033673125,0.010001124,0.029293139,0.61457866,0.0003824747,0.04630875,0.00045015625],"about_ca_topic_score_codex":0.0000073734113,"about_ca_topic_score_gemma":0.000007660005,"teacher_disagreement_score":0.37870324,"about_ca_system_score_codex":0.000019341249,"about_ca_system_score_gemma":0.00009394688,"threshold_uncertainty_score":0.13553983},"labels":[],"label_agreement":null},{"id":"W3000666210","doi":"10.1534/g3.119.400813","title":"Type I-F CRISPR-Cas Distribution and Array Dynamics in <i>Legionella pneumophila</i>","year":2020,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Legionella pneumophila; Biology; Plasmid; Computational biology; Genetics; DNA; Bacteria; Gene","score_opus":0.009753622033832609,"score_gpt":0.2615731311125946,"score_spread":0.251819509078762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000666210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6315876,0.3264858,0.03934039,0.0011739982,0.00039009648,0.00038822438,0.00012500054,0.00004233259,0.00046649866],"genre_scores_gemma":[0.91644263,0.08096683,0.0012423265,0.00041182878,0.0003624914,0.000009584418,0.0004514956,0.00004260398,0.00007023616],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.998704,0.000029176697,0.00028783368,0.00049409486,0.00013043065,0.00035442642],"domain_scores_gemma":[0.99936455,0.0000080989375,0.000055449236,0.00030258682,0.00007111143,0.00019819122],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008420531,0.00025201798,0.00021064446,0.000034778517,0.000059770482,0.000037063048,0.000192674,0.00018142526,0.000003755663],"category_scores_gemma":[0.00000992587,0.00027991843,0.00006024981,0.00022527232,0.00006797326,0.0000029654423,0.00014784237,0.00011810358,0.0000137463985],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011526411,0.00005731881,0.060295653,0.00013508361,0.00006904334,0.000017744966,0.0003317003,0.0104312515,0.75073254,0.00012366966,0.00088841276,0.17680234],"study_design_scores_gemma":[0.0012906445,0.0008782667,0.009267972,0.000020489399,0.00007935829,0.00007830717,0.00065977045,0.014033019,0.4483595,0.00014943196,0.5240536,0.0011296918],"about_ca_topic_score_codex":0.000007854249,"about_ca_topic_score_gemma":0.00007787258,"teacher_disagreement_score":0.52316517,"about_ca_system_score_codex":0.000038487786,"about_ca_system_score_gemma":0.00005320771,"threshold_uncertainty_score":0.9999653},"labels":[],"label_agreement":null},{"id":"W3000684857","doi":"10.1016/b978-0-12-817240-7.00003-6","title":"How are genes modified? Crossbreeding, mutagenesis, and CRISPR-Cas9","year":2020,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Genetics; Mutagenesis; Biology; Crossbreed; Gene; Cas9; Genome editing; Computational biology; Mutation","score_opus":0.015326973855551365,"score_gpt":0.2581335885414877,"score_spread":0.24280661468593634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000684857","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002787176,0.07127726,0.0015103972,0.0005361442,0.00076520356,0.0008424208,0.00025055654,0.000110417604,0.9219204],"genre_scores_gemma":[0.061531685,0.0024120416,0.00057652354,0.0004015439,0.0015238166,0.000035857985,0.00010533348,0.00018883708,0.9332244],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99843603,0.000011307686,0.000261474,0.0007780124,0.00020171516,0.0003114847],"domain_scores_gemma":[0.99901533,0.00000877839,0.00016038322,0.00049425306,0.00008652922,0.00023474026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007835039,0.0005469615,0.00046615538,0.00006459248,0.00011387977,0.00014869045,0.00025639086,0.0005282044,0.00001395358],"category_scores_gemma":[0.000024874635,0.00056091876,0.00022026364,0.000009267841,0.00013853083,0.0000024892597,0.0003223475,0.00025359233,0.000010014256],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004503192,0.0000066547464,0.000057053698,0.00041726523,0.00033473238,0.00008280791,0.00008240241,0.000028658818,0.08420078,0.0007140842,0.0012336478,0.91279685],"study_design_scores_gemma":[0.00030447848,0.00011975341,0.00005218352,0.00010043822,0.0001289924,0.00005611652,0.000024179695,0.00003114215,0.032201666,0.00030334727,0.9660217,0.0006559908],"about_ca_topic_score_codex":4.2762065e-7,"about_ca_topic_score_gemma":0.00001639361,"teacher_disagreement_score":0.9647881,"about_ca_system_score_codex":0.000014337408,"about_ca_system_score_gemma":0.00004932708,"threshold_uncertainty_score":0.9996842},"labels":[],"label_agreement":null},{"id":"W3000693105","doi":"10.1002/cpmo.67","title":"Efficient Generation of Large‐Fragment Knock‐In Mouse Models Using 2‐Cell (2C)‐Homologous Recombination (HR)‐CRISPR","year":2020,"lang":"en","type":"article","venue":"Current Protocols in Mouse Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Ontario Genomics Institute","keywords":"CRISPR; Biology; Computational biology; Gene knockin; Homologous recombination; Cas9; Guide RNA; Genome editing; Genetics; DNA; Gene","score_opus":0.05958662402793901,"score_gpt":0.38955082903376975,"score_spread":0.32996420500583074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000693105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8668407,0.000649545,0.12017693,0.000041264022,0.00014855718,0.0120443115,0.000047886268,0.00001712379,0.00003365142],"genre_scores_gemma":[0.9920667,0.00007714046,0.0015678309,0.00004914972,0.0001410343,0.0058880863,0.00016063378,0.000028556045,0.000020889569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982873,0.00016562101,0.0005604854,0.00052208465,0.00009797252,0.00036649115],"domain_scores_gemma":[0.99940246,0.000010769886,0.00015399355,0.00027659975,0.00007737019,0.00007878938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003137627,0.00022418486,0.00029264373,0.00012020522,0.000033542645,0.000010416617,0.00022165218,0.00023483326,0.000011185554],"category_scores_gemma":[0.00006901593,0.00023197975,0.00007937457,0.00015846493,0.000043862357,0.0000044686285,0.00013573394,0.00018976808,0.000002192729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007249721,0.00037112818,0.0014253414,0.0001382066,0.0000067190003,0.0000010215273,0.00019323129,0.1753447,0.8210946,0.00014415478,0.000055608314,0.0011528311],"study_design_scores_gemma":[0.001585009,0.00042088874,0.000047386275,0.000030896877,0.0000046300415,0.0000016021187,0.000036582125,0.23363648,0.7628436,0.00004174691,0.0011261564,0.00022500036],"about_ca_topic_score_codex":0.0000146129305,"about_ca_topic_score_gemma":0.000022745122,"teacher_disagreement_score":0.12522595,"about_ca_system_score_codex":0.00006226798,"about_ca_system_score_gemma":0.00007986076,"threshold_uncertainty_score":0.945986},"labels":[],"label_agreement":null},{"id":"W3001297896","doi":"10.3389/fphys.2019.01585","title":"CRISPR/Cas9-Mediated Vitellogenin Receptor Knockout Leads to Functional Deficiency in the Reproductive Development of Plutella xylostella","year":2020,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Natural Science Foundation of Fujian Province; National Natural Science Foundation of China","keywords":"Vitellogenin; Biology; Diamondback moth; Plutella; Mutant; Genetics; LDL receptor; Gene; Endocrinology; Botany; Lipoprotein; Cholesterol","score_opus":0.012136312356254005,"score_gpt":0.25391869931034283,"score_spread":0.24178238695408882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3001297896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9816172,0.0011883301,0.015867298,0.0004186328,0.00047028085,0.00026493808,0.000010595659,0.00000667632,0.0001560438],"genre_scores_gemma":[0.9911227,0.00005325282,0.007940161,0.0004959235,0.00019158059,0.00003669812,0.00010556873,0.000015035161,0.000039044084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987391,0.00008991712,0.000318457,0.00048311093,0.00010723374,0.00026217056],"domain_scores_gemma":[0.99957913,0.000020119092,0.00005380128,0.00025050595,0.000043944507,0.000052526673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019778457,0.00015228947,0.0002241255,0.00008140341,0.000030374244,0.0000035596304,0.0002525552,0.00012375384,0.000015727583],"category_scores_gemma":[0.0001859813,0.00013164991,0.000050955376,0.00032556042,0.00007060905,0.0000022945603,0.000107420754,0.00013909629,0.000013695774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024767037,0.00005902993,0.0030575034,0.000024297426,0.000016816866,0.0000011130602,0.0023378627,0.005129995,0.9760836,0.00000672013,0.011555638,0.001479779],"study_design_scores_gemma":[0.0005204476,0.00031222246,0.022494059,0.000010952678,0.00000692568,0.000002917285,0.001699161,0.00017917622,0.9607564,0.00003217374,0.01373647,0.00024906266],"about_ca_topic_score_codex":0.0000048633856,"about_ca_topic_score_gemma":0.000010546961,"teacher_disagreement_score":0.019436557,"about_ca_system_score_codex":0.000022278184,"about_ca_system_score_gemma":0.000079550264,"threshold_uncertainty_score":0.5368528},"labels":[],"label_agreement":null},{"id":"W3001704276","doi":"10.1073/pnas.1902766117","title":"De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Cancer Institute; National Institutes of Health; Sleep Research Society; American Thoracic Society","keywords":"Genetics; Biology; Heritability; Mutation rate; Population; Genetic variation; Genome; Loss of heterozygosity; Evolutionary biology; Gene; Allele; Demography","score_opus":0.03405580444134087,"score_gpt":0.3465918529088312,"score_spread":0.31253604846749033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3001704276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621546,0.00021901299,0.000027074828,0.0031630322,0.000008610094,0.00009154378,0.000011680514,0.000002107449,0.00026149236],"genre_scores_gemma":[0.99838614,0.000029249351,0.0011611616,0.00030438366,0.00008982199,0.0000070152423,0.000001612011,0.000001972125,0.000018663528],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993933,0.0000052862474,0.00013682355,0.00013111603,0.000257503,0.00007599914],"domain_scores_gemma":[0.99980223,0.000022239716,0.0000782728,0.0000051560037,0.00007330876,0.00001880719],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026086328,0.0000465588,0.00004780379,0.000028709668,0.00014719651,0.000020957272,0.000199973,0.00004297834,0.0000015961522],"category_scores_gemma":[0.00019745537,0.000032405424,0.000026113987,0.00026450603,0.0002244776,0.000019960544,0.000055933808,0.00006376574,1.2018674e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001827261,0.00003668081,0.04416325,0.000054969852,0.00002210509,2.5294288e-8,0.004323707,0.009194055,0.93109006,0.009922555,0.0003049871,0.00086933037],"study_design_scores_gemma":[0.00031165368,0.000064962274,0.88565135,0.000023577591,0.000014209649,0.000036776633,0.003821012,0.002357195,0.09125106,0.015854532,0.00050313567,0.000110513254],"about_ca_topic_score_codex":0.000005256537,"about_ca_topic_score_gemma":6.72788e-7,"teacher_disagreement_score":0.8414881,"about_ca_system_score_codex":0.000008397756,"about_ca_system_score_gemma":0.000016399326,"threshold_uncertainty_score":0.13214548},"labels":[],"label_agreement":null},{"id":"W3002143230","doi":"10.3390/ijms21030733","title":"Genome Editing for the Understanding and Treatment of Inherited Cardiomyopathies","year":2020,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Muscular Dystrophy Canada; University of Alberta; Canadian Institutes of Health Research; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Transcription activator-like effector nuclease; Genome editing; Zinc finger nuclease; CRISPR; Duchenne muscular dystrophy; Cardiomyopathy; Biology; Genome; Computational biology; Genome engineering; Muscle disease; Genetics; Bioinformatics; Medicine; Disease; Gene; Heart failure; Internal medicine","score_opus":0.06121968719885937,"score_gpt":0.374863738915066,"score_spread":0.3136440517162067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002143230","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00042961378,0.9435798,0.055332802,0.000116597395,0.00036724916,0.00012656374,0.000021752503,9.373613e-7,0.000024674522],"genre_scores_gemma":[0.021027876,0.9773743,0.0010412869,0.00001331191,0.00051751937,0.0000059556655,0.000006226033,0.000009145648,0.0000043402224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992635,0.000026676742,0.00029856013,0.00012310952,0.00021095472,0.00007714442],"domain_scores_gemma":[0.999468,0.00005562007,0.00029028085,0.00005659846,0.00009765892,0.000031815576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002220637,0.0001143367,0.0003078129,0.0000839872,0.000041987263,0.000045329336,0.00031225596,0.000051148923,9.015563e-7],"category_scores_gemma":[0.00007342202,0.000071190254,0.00027893874,0.00007013784,0.00011866341,0.0000032169594,0.00005244129,0.000040145744,6.3721735e-8],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029275527,0.000032875396,0.000016724416,0.0005029648,0.0018981302,0.000054597516,0.0002824088,0.001171607,0.018750733,0.00044774218,0.000033234995,0.9767797],"study_design_scores_gemma":[0.00027045922,0.0006738597,0.000008554347,0.0005838796,0.0003322875,0.00043932916,0.00036940372,0.00008620128,0.0019005944,0.000075577766,0.99513465,0.00012518682],"about_ca_topic_score_codex":0.0000016893102,"about_ca_topic_score_gemma":0.0000010085608,"teacher_disagreement_score":0.99510145,"about_ca_system_score_codex":0.00003282355,"about_ca_system_score_gemma":0.0001274596,"threshold_uncertainty_score":0.29030544},"labels":[],"label_agreement":null},{"id":"W3002880036","doi":"10.1016/j.enzmictec.2020.109508","title":"CRISPR/Cas9 facilitates rapid generation of constitutive forms of transcription factors in Aspergillus niger through specific on-site genomic mutations resulting in increased saccharification of plant biomass","year":2020,"lang":"en","type":"article","venue":"Enzyme and Microbial Technology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Consejo Nacional de Ciencia y Tecnología; Concordia University; Academy of Finland","keywords":"Aspergillus niger; Biology; CRISPR; Gene; Genetics; Cas9; genomic DNA; Genome editing; Biochemistry","score_opus":0.022656709368567035,"score_gpt":0.25418997362551043,"score_spread":0.2315332642569434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002880036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99268657,0.0010449007,0.005593954,0.0000954029,0.000036126676,0.00021698848,0.0002964002,0.000007434026,0.000022232649],"genre_scores_gemma":[0.998554,0.00038903076,0.00066972006,0.000012316113,0.000014027029,0.0000064629926,0.0003461543,0.00000663377,0.000001684982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922884,0.000021973121,0.0003858154,0.00021798021,0.000035843077,0.00010952584],"domain_scores_gemma":[0.9997223,0.000013088974,0.00010355542,0.00010870902,0.000036721452,0.00001564792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007697316,0.00010314377,0.00019580813,0.00016093702,0.000018145267,0.0000025231345,0.000066293505,0.0001739067,0.0000035264652],"category_scores_gemma":[0.00005222873,0.00010249319,0.000035637564,0.00018783321,0.00014151327,0.000007042084,0.000020176161,0.000078274235,3.7166873e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078197656,0.000040483,0.002500637,0.00004346093,0.000015229231,8.774283e-7,0.0012062247,0.0004194913,0.9950051,0.00034746717,0.000025636615,0.00031723527],"study_design_scores_gemma":[0.00082144496,0.00023814755,0.0029613196,0.000025018633,0.000006895619,0.0000026937237,0.00066812825,0.00014827345,0.9944673,0.00003443455,0.0005363224,0.00009000147],"about_ca_topic_score_codex":0.000118718955,"about_ca_topic_score_gemma":0.00014155921,"teacher_disagreement_score":0.00586741,"about_ca_system_score_codex":0.0000123869595,"about_ca_system_score_gemma":0.000026669695,"threshold_uncertainty_score":0.4179551},"labels":[],"label_agreement":null},{"id":"W3003209623","doi":"10.1038/s41467-020-14284-2","title":"Human and mouse essentiality screens as a resource for disease gene discovery","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; SickKids Foundation; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"Agence Nationale de la Recherche; National Center for Research Resources; National Eye Institute; INFRAFRONTIER; National Heart, Lung, and Blood Institute; Medical Research Council; Centre National de la Recherche Scientifique; Université de Strasbourg; PHENOMIN; Institut National de la Santé et de la Recherche Médicale; National Human Genome Research Institute; Cancer Research UK; Wellcome Trust; National Institute for Health and Care Research; National Institutes of Health; Ontario Genomics; Genome Canada; FP7 Health; Yale University; Johns Hopkins University; University of Washington; Broad Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Government of Canada","keywords":"Computational biology; Gene; Resource (disambiguation); Human disease; Biology; Disease; Computer science; Genetics; Medicine","score_opus":0.015945508400426668,"score_gpt":0.3410416106375163,"score_spread":0.3250961022370896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003209623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.911876,0.029645666,0.035704248,0.019960914,0.000052370917,0.0008274179,0.00060350733,0.00007418745,0.001255676],"genre_scores_gemma":[0.9946378,0.00024704894,0.0028705562,0.0011016519,0.00011703179,0.000034699693,0.00065731106,0.00001586921,0.000318043],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995614,0.000027476162,0.00009372947,0.00017635299,0.000047288926,0.00009374907],"domain_scores_gemma":[0.9990861,0.000015105677,0.000025776957,0.000722319,0.000036423917,0.0001142708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000537135,0.00007919984,0.00006761849,0.000011369752,0.00016333886,0.00003380673,0.00031854011,0.000101913494,0.0000017366572],"category_scores_gemma":[0.000121421166,0.00008256686,0.00005406456,0.00004364303,0.00006299391,0.000003215624,0.00030373211,0.00015398528,6.8298e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058946913,0.00006540676,0.0010957833,0.000040400704,0.00006176876,4.5491666e-7,0.00009307792,0.00012742604,0.98514116,0.003219972,0.009672336,0.00042326874],"study_design_scores_gemma":[0.0009970659,0.00016942233,0.010780783,0.00001408596,0.00012583744,0.0000037897419,0.00016509344,0.0014280267,0.22814429,0.00022142434,0.75752246,0.00042772494],"about_ca_topic_score_codex":0.0000053460712,"about_ca_topic_score_gemma":0.00003824718,"teacher_disagreement_score":0.75699687,"about_ca_system_score_codex":0.0000032650992,"about_ca_system_score_gemma":0.000020881771,"threshold_uncertainty_score":0.3366979},"labels":[],"label_agreement":null},{"id":"W3003342303","doi":"10.1016/j.tibtech.2019.12.022","title":"Geneva Statement on Heritable Human Genome Editing: The Need for Course Correction","year":2020,"lang":"en","type":"review","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Fondation Brocher","keywords":"Statement (logic); Course (navigation); Human genome; Computational biology; Genome; Biology; Genetics; Computer science; Philosophy; Gene; Engineering; Linguistics","score_opus":0.0321895589466304,"score_gpt":0.38604723466532137,"score_spread":0.353857675718691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003342303","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000066536064,0.99558383,0.0018042703,0.00069163676,0.000899098,0.0005091201,0.00009031787,0.0000666083,0.0002886089],"genre_scores_gemma":[0.0009162374,0.9952156,0.00031423185,0.00007373922,0.000687292,0.0003981339,0.0009872047,0.00008338978,0.0013241811],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985115,0.00004278346,0.00044811476,0.0005433033,0.00008032254,0.00037400023],"domain_scores_gemma":[0.9992263,0.000019258763,0.00017290599,0.00052243145,0.000019214905,0.000039940798],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018096526,0.0003495852,0.0006106911,0.00019512638,0.00009142574,0.000017473903,0.0004149252,0.0007617213,0.000021381635],"category_scores_gemma":[0.00003546561,0.0002763514,0.0002342124,0.00032606607,0.000082432794,0.0000010457379,0.00014700841,0.00040525995,0.00000848096],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011067026,0.00005924197,8.2144993e-7,0.0004407764,0.00013735694,0.000005080651,0.000014236098,0.00010103804,0.0028336882,0.00017046832,0.0070079165,0.9892183],"study_design_scores_gemma":[0.00025282518,0.0005444566,0.000003925819,0.0001916599,0.00012730833,0.000020227966,0.000042638723,0.000049876693,0.0030639332,0.000013084833,0.9954327,0.00025739858],"about_ca_topic_score_codex":0.000009185594,"about_ca_topic_score_gemma":0.000065628534,"teacher_disagreement_score":0.9889609,"about_ca_system_score_codex":0.000063905405,"about_ca_system_score_gemma":0.00004988571,"threshold_uncertainty_score":0.9999689},"labels":[],"label_agreement":null},{"id":"W3003386920","doi":"10.1007/978-1-0716-0290-4_21","title":"Genome Editing in Zebrafish Using High-Fidelity Cas9 Nucleases: Choosing the Right Nuclease for the Task","year":2020,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AGADA Biosciences; Dalhousie University; Agricultural Research Institute of Ontario","funders":"","keywords":"Cas9; Genome editing; CRISPR; Computational biology; Biology; Zebrafish; Mutagenesis; Nuclease; Genome; Genetics; Computer science; Mutation; Gene","score_opus":0.020226550463352113,"score_gpt":0.3906998122064582,"score_spread":0.37047326174310613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003386920","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19895408,0.0022195815,0.796732,0.0012549517,0.000279595,0.0004722856,0.000027653381,0.000012722051,0.000047100086],"genre_scores_gemma":[0.73127764,0.0000593766,0.26579836,0.0021251272,0.0005658359,0.00006451311,0.000047537476,0.000054843902,0.0000067926626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979459,0.0005751954,0.00041942723,0.0005359026,0.00006686705,0.0004567145],"domain_scores_gemma":[0.9991394,0.00019279779,0.000100142955,0.00043658086,0.00005055265,0.00008052417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012091944,0.00023258821,0.0002781226,0.000050027003,0.00013227346,0.000032620203,0.0004633063,0.00021859207,0.00002126092],"category_scores_gemma":[0.0011048435,0.00016846007,0.00015068865,0.00024768506,0.00014710026,0.0000034846898,0.0002593624,0.00027527064,0.000001126442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004363979,0.000017638555,0.00023446004,0.000023715163,0.000039649225,0.000007270252,0.00013050094,0.010643882,0.98630697,0.00026864727,0.00003438404,0.0022492465],"study_design_scores_gemma":[0.0019402723,0.0003658746,0.0032080163,0.00003986714,0.00012723356,0.000046415993,0.00062080676,0.053010993,0.8620905,0.0019804803,0.07583411,0.0007353836],"about_ca_topic_score_codex":0.00012257225,"about_ca_topic_score_gemma":0.000043724984,"teacher_disagreement_score":0.53232354,"about_ca_system_score_codex":0.00003224434,"about_ca_system_score_gemma":0.00005063217,"threshold_uncertainty_score":0.6869603},"labels":[],"label_agreement":null},{"id":"W3003606106","doi":"10.1007/s00018-020-03449-3","title":"EMT signaling: potential contribution of CRISPR/Cas gene editing","year":2020,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Guelph","funders":"","keywords":"CRISPR; Biology; Epithelial–mesenchymal transition; Gene; Genome editing; Metastasis; Computational biology; Genetics; Bioinformatics; Cancer","score_opus":0.0144541548331145,"score_gpt":0.3110766051132627,"score_spread":0.29662245028014816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003606106","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00091630075,0.8830868,0.115278214,0.00003120611,0.000299963,0.00027352222,0.000030281264,0.000011588807,0.00007211519],"genre_scores_gemma":[0.059091896,0.9389832,0.0010268338,0.00006166515,0.0005522775,0.000016898477,0.00021916638,0.000032895357,0.000015170311],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99817103,0.000104194194,0.0004798939,0.0006345962,0.0002853704,0.0003249251],"domain_scores_gemma":[0.9992272,0.000013860257,0.00024366837,0.00022492492,0.000083217565,0.00020710913],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037303605,0.00033563634,0.0007304196,0.00009643443,0.00013047787,0.00004493569,0.00033491867,0.00027947745,0.000007960534],"category_scores_gemma":[0.00022437576,0.00030124732,0.00036482376,0.00024323742,0.00025547124,0.000004249686,0.0002223088,0.00015648884,0.0000031807308],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015569,0.000050351136,0.0000090326375,0.0034101936,0.00035589328,0.00010644028,0.00005540392,0.00043820325,0.86840165,0.00023993442,0.00038681205,0.1265305],"study_design_scores_gemma":[0.00021655935,0.00025125034,0.0000010497572,0.0005446062,0.00046131358,0.000052282554,0.000045747696,0.00018217061,0.43092588,0.000026057807,0.566874,0.00041908445],"about_ca_topic_score_codex":0.000005582906,"about_ca_topic_score_gemma":4.8596524e-7,"teacher_disagreement_score":0.5664872,"about_ca_system_score_codex":0.000007734235,"about_ca_system_score_gemma":0.0002517573,"threshold_uncertainty_score":0.999944},"labels":[],"label_agreement":null},{"id":"W3003759327","doi":"10.3389/fgeed.2020.00001","title":"New Opportunities to Meet the Grand Challenges in Infectious Diseases","year":2020,"lang":"en","type":"editorial","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Grand Challenges; Virology; Medicine; Political science","score_opus":0.014410256817257978,"score_gpt":0.26207583194364104,"score_spread":0.24766557512638307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003759327","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000806973,0.066264704,0.007864782,0.0012844928,0.9203088,0.00059508916,0.00024384227,0.00004638207,0.0025849154],"genre_scores_gemma":[0.009827595,0.009129011,0.0010201088,0.000128237,0.9788171,0.00010867842,0.00042823804,0.000107891254,0.00043311252],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99840266,0.000066532666,0.00033442615,0.0005236637,0.00027230944,0.00040039438],"domain_scores_gemma":[0.9993057,0.00005597727,0.000086594344,0.00032372194,0.00004488012,0.00018308187],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002166097,0.0003193918,0.00038162418,0.00016716844,0.000056023026,0.00005296112,0.00040115713,0.0003898442,0.000005094234],"category_scores_gemma":[0.00065233465,0.00030241357,0.000101103724,0.000107798034,0.000035360048,0.0000040635928,0.00022965806,0.0003308898,0.0000014986853],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029851413,0.000010834005,0.00032307833,0.00011573383,0.000051499104,0.000025605577,0.0005943031,0.0010904957,0.00024737345,0.0000062485233,0.9909717,0.0065333056],"study_design_scores_gemma":[0.00045182026,0.00012418133,0.00021201822,0.00008480663,0.000029235287,0.0000011428383,0.0010253153,0.000018521921,0.00013349146,0.00013457518,0.99744034,0.0003445548],"about_ca_topic_score_codex":0.000033183882,"about_ca_topic_score_gemma":0.00039592278,"teacher_disagreement_score":0.058508307,"about_ca_system_score_codex":0.00006735363,"about_ca_system_score_gemma":0.000259853,"threshold_uncertainty_score":0.9999428},"labels":[],"label_agreement":null},{"id":"W3004270985","doi":"10.1128/jb.00644-19","title":"HK97 gp74 Possesses an α-Helical Insertion in the ββα Fold That Affects Its Metal Binding, <i>cos</i> Site Digestion, and <i>In Vivo</i> Activities","year":2020,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Binding site; In vivo; Fold (higher-order function); Biochemistry; Plasma protein binding; Metal; Digestion (alchemy); Molecular biology; Genetics; Chemistry","score_opus":0.013154327263598602,"score_gpt":0.27424661195321975,"score_spread":0.26109228468962115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004270985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99777305,0.0008877544,0.00027930713,0.0007816626,0.00014985439,0.00008339228,0.000008839875,0.0000031439615,0.00003296536],"genre_scores_gemma":[0.9982536,0.00072273274,0.00009494111,0.00059581146,0.0002982883,0.000003998104,0.000010672138,0.000011118532,0.000008860157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999249,0.00015389208,0.00019052517,0.00015819157,0.0000783507,0.00017008606],"domain_scores_gemma":[0.9996635,0.00004597244,0.000111363464,0.0000876774,0.000021020263,0.000070475115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024695945,0.00012468056,0.00021787478,0.00006547289,0.000027999504,0.000029200177,0.00013432282,0.00012907392,0.000007676216],"category_scores_gemma":[0.00008340523,0.000093176954,0.00005539256,0.00007879919,0.000041334424,0.000022826744,0.000045656776,0.0001952027,5.891182e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018849877,0.000037486232,0.031106658,0.000022073806,0.00001790465,0.000018901976,0.00029238017,0.00018701391,0.9677424,0.000008324383,0.00015365593,0.00022472505],"study_design_scores_gemma":[0.0014205349,0.0022657781,0.268965,0.00006241876,0.00004468386,0.0007891863,0.000558298,0.00016332972,0.71107024,0.000016249794,0.014365256,0.00027900012],"about_ca_topic_score_codex":0.000004860062,"about_ca_topic_score_gemma":0.00007764576,"teacher_disagreement_score":0.2566721,"about_ca_system_score_codex":0.0000088095,"about_ca_system_score_gemma":0.00003355669,"threshold_uncertainty_score":0.3799646},"labels":[],"label_agreement":null},{"id":"W3004357814","doi":"10.3390/genes11020140","title":"Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What’s Next","year":2020,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Fragment (logic); Gene knockin; CRISPR; Genome editing; Computational biology; Biology; Endonuclease; Cas9; Genome; Animal model; Genetics; Synthetic biology; Restriction enzyme; Computer science; DNA; Gene","score_opus":0.02268235043317289,"score_gpt":0.3197516966472002,"score_spread":0.2970693462140273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004357814","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00054115703,0.9978035,0.0008085635,0.00017317313,0.00024363674,0.0003817118,0.00002026981,0.000009158179,0.000018799812],"genre_scores_gemma":[0.0005904324,0.99824756,0.0003481055,0.0001444728,0.00022926195,0.00010434498,0.00020299054,0.000048244485,0.000084555904],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987344,0.00007380243,0.00027014906,0.00051348953,0.00009163048,0.00031649688],"domain_scores_gemma":[0.9995207,0.000016335816,0.000066239976,0.00029316446,0.000013748109,0.000089792346],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014786699,0.0003318521,0.00065475336,0.000104963154,0.000019829562,0.0001405481,0.00017967215,0.00031234018,0.000012674247],"category_scores_gemma":[0.000027315464,0.0003138577,0.00015456075,0.00014193953,0.000020068483,0.0000066298016,0.00014597998,0.0001564857,0.0000057423417],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000054915763,0.000029831142,0.000028190081,0.0036000465,0.000035277953,0.0000392348,0.000020001673,0.00004860194,0.0009525054,0.0000052147575,0.00036766296,0.9948679],"study_design_scores_gemma":[0.0003074005,0.00006170109,0.000023481583,0.0014933413,0.00004894935,0.000010534262,0.000093045295,0.00008912698,0.0008267398,0.000002019562,0.9967151,0.00032852092],"about_ca_topic_score_codex":0.0000079528045,"about_ca_topic_score_gemma":0.00015381153,"teacher_disagreement_score":0.9963475,"about_ca_system_score_codex":0.000021022362,"about_ca_system_score_gemma":0.00010850589,"threshold_uncertainty_score":0.99993134},"labels":[],"label_agreement":null},{"id":"W3004467187","doi":"10.1242/jeb.218198","title":"How to turn an organism into a model organism in 10 ‘easy’ steps","year":2020,"lang":"en","type":"review","venue":"Journal of Experimental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; University of British Columbia; Georgia Clinical and Translational Science Alliance; National Center for Advancing Translational Sciences; Howard Hughes Medical Institute","keywords":"Model organism; Biology; Organism; CRISPR; Drosophila melanogaster; Caenorhabditis elegans; Drosophila (subgenus); Genetics; Genome; Computational biology; Evolutionary biology; Gene","score_opus":0.022170383411650778,"score_gpt":0.3795835552847756,"score_spread":0.3574131718731248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004467187","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002862464,0.9932923,0.00303006,0.0000919514,0.00035576685,0.00027846007,0.000023296941,0.000006582702,0.000059163147],"genre_scores_gemma":[0.033326022,0.9574897,0.0073702014,0.00025532575,0.0010588825,0.000024803352,0.00012733125,0.000115586045,0.00023211808],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99840426,0.00012449958,0.0006386247,0.00042187326,0.00010976618,0.00030095442],"domain_scores_gemma":[0.99902755,0.000012204217,0.00029943624,0.00029327284,0.000067116605,0.00030039912],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016244341,0.00041764972,0.0011227952,0.00018886903,0.000029925519,0.000041385312,0.00056019035,0.000502005,0.00003476897],"category_scores_gemma":[0.00008663889,0.0003448077,0.000301419,0.00016005819,0.00004419598,0.0000074863174,0.00027359164,0.00034211008,0.000012384153],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006594689,0.00015085643,0.0000028839988,0.00029002043,0.00017170879,0.00006169799,0.00044550982,0.00004495182,0.91109854,0.000034826317,0.0007158021,0.08691727],"study_design_scores_gemma":[0.00045751006,0.0024181043,4.1160214e-7,0.00033663574,0.000075339536,0.00035975725,0.00029204623,0.00003417888,0.11565628,0.000022402694,0.8799052,0.00044208305],"about_ca_topic_score_codex":0.0000035221758,"about_ca_topic_score_gemma":0.000007643012,"teacher_disagreement_score":0.87918943,"about_ca_system_score_codex":0.000107816246,"about_ca_system_score_gemma":0.0002720561,"threshold_uncertainty_score":0.9999004},"labels":[],"label_agreement":null},{"id":"W3004591611","doi":"10.1016/j.mrrev.2020.108298","title":"Deciphering and simulating models of radiation genotoxicity with CRISPR/Cas9 systems","year":2020,"lang":"en","type":"review","venue":"Mutation Research/Reviews in Mutation Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canada Research Chairs; CANDU Owners Group; National CFIDS Foundation; Bruce Power","keywords":"CRISPR; Genotoxicity; Computational biology; Biology; Computer science; Genetics; Chemistry; Gene","score_opus":0.18487976573276096,"score_gpt":0.5053958065673048,"score_spread":0.32051604083454377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004591611","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012293549,0.9684961,0.026182413,0.000024863271,0.000052906733,0.003682866,0.000031077063,0.000012912329,0.00028751956],"genre_scores_gemma":[0.02218151,0.9748386,0.0013920318,0.0000053462595,0.00019324511,0.0008767545,0.00032988295,0.000092892195,0.000089730194],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9934538,0.0025960165,0.0012571216,0.00089345424,0.0011395455,0.0006600736],"domain_scores_gemma":[0.9975921,0.00067697593,0.00032594503,0.00050691114,0.0006765331,0.00022157142],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006420528,0.00037477416,0.0011901719,0.00082080805,0.00020109743,0.00015100009,0.00039789334,0.00037442616,0.000011827388],"category_scores_gemma":[0.0019110857,0.00032766533,0.000147566,0.0017050891,0.00023825667,0.00003019827,0.00026983075,0.0010210873,0.00001578044],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004248926,0.000045478773,0.000021889184,0.019772232,0.00007825613,0.000043649197,0.00050794065,0.034620576,0.0003812069,0.00015051725,0.00013740596,0.94419837],"study_design_scores_gemma":[0.001421362,0.0012135261,0.000069605456,0.017361231,0.0001367294,0.00013611041,0.0013049699,0.107217185,0.0013902086,0.00024988473,0.8684854,0.00101378],"about_ca_topic_score_codex":0.000167179,"about_ca_topic_score_gemma":0.00007062427,"teacher_disagreement_score":0.94318455,"about_ca_system_score_codex":0.00019341792,"about_ca_system_score_gemma":0.0005801222,"threshold_uncertainty_score":0.99991757},"labels":[],"label_agreement":null},{"id":"W3005354177","doi":"10.1186/s13059-020-1931-9","title":"The Deep Genome Project","year":2020,"lang":"en","type":"editorial","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Centre for Phenogenomics; SickKids Foundation; Lunenfeld-Tanenbaum Research Institute; Hospital for Sick Children; Jewish General Hospital; University of Ottawa; McGill University; Children's Hospital of Eastern Ontario","funders":"National Human Genome Research Institute; National Institutes of Health; British Heart Foundation; Medical Research Council; National Institute for Health and Care Research","keywords":"Biology; Genome; Computational biology; Model organism; Human genome; Genome project; In silico; Human genetics; Genetics; Genome editing; Genomics; Functional genomics; Recombineering; Gene","score_opus":0.006647654259008924,"score_gpt":0.30670994835948545,"score_spread":0.3000622941004765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005354177","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00081311073,0.05378185,0.007089799,0.00033650995,0.9336541,0.0009196618,0.0007020429,0.00008689993,0.0026160122],"genre_scores_gemma":[0.0046856143,0.0075194025,0.00040111787,0.00012655965,0.97941077,0.00015214771,0.005581703,0.000117331576,0.002005372],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981351,0.00009737944,0.0003421905,0.00072136143,0.00014165996,0.0005622935],"domain_scores_gemma":[0.99890494,0.000089108114,0.00012883703,0.0006581986,0.00012050334,0.000098427416],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002334903,0.00038920334,0.00034043824,0.000045660738,0.00018302826,0.0000477282,0.00080319337,0.0010803957,0.000015414284],"category_scores_gemma":[0.00042568956,0.00029355215,0.00020280121,0.0001035329,0.00015506089,7.756356e-7,0.0004360166,0.00048084682,0.00008018788],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011325675,0.000015154058,0.0000129764285,0.00006381125,0.00032889724,0.0000073426754,0.00007778579,0.000050094153,0.32797647,0.00003149444,0.66923684,0.0020858923],"study_design_scores_gemma":[0.00024166297,0.0004289043,0.00004693999,0.0000025703107,0.000037421534,0.000004453547,0.000026828053,0.0000072726716,0.0010449429,0.000031923326,0.99776244,0.00036465595],"about_ca_topic_score_codex":0.000019429524,"about_ca_topic_score_gemma":0.00006115622,"teacher_disagreement_score":0.3285256,"about_ca_system_score_codex":0.00003187102,"about_ca_system_score_gemma":0.0003104394,"threshold_uncertainty_score":0.99995166},"labels":[],"label_agreement":null},{"id":"W3005373577","doi":"10.2139/ssrn.3526892","title":"Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds Against &lt;i&gt;Klebsiella pneumoniae&lt;/i&gt;","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Klebsiella pneumoniae; Microbiology; Klebsiella; Biology; Antibacterial activity; Bacteria; Genetics; Gene; Escherichia coli","score_opus":0.005025630208099595,"score_gpt":0.2354425418015884,"score_spread":0.23041691159348882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005373577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98604757,0.010583001,0.0026570745,0.00035086667,0.000051619336,0.00014268963,0.00000809414,0.000014953522,0.0001441355],"genre_scores_gemma":[0.99052894,0.00805167,0.00057732896,0.00015754801,0.00055576226,0.0000038391613,0.000025639218,0.000045275054,0.000053987966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779576,0.00007640048,0.00037472713,0.0004137458,0.00014056473,0.0011987954],"domain_scores_gemma":[0.9994786,0.0000119325505,0.00009860916,0.00015083225,0.000041479736,0.0002185874],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039735754,0.00026628378,0.00028964467,0.000064243,0.00012530161,0.00007190836,0.00019722647,0.00019917173,0.0000038102614],"category_scores_gemma":[0.00004500991,0.00028204874,0.00007325477,0.00010297191,0.0000763901,0.000008786322,0.0001963359,0.000654948,5.9741006e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049256927,0.000028548431,0.0040225154,0.000025345333,0.000102101796,0.000016838932,0.00008291828,0.000102851714,0.9928609,0.000282906,0.000039285667,0.0023865297],"study_design_scores_gemma":[0.012502558,0.0032544383,0.076549225,0.00030723496,0.00034079485,0.0037497715,0.00043664227,0.0019091966,0.8793938,0.0053000627,0.013594063,0.0026621781],"about_ca_topic_score_codex":0.000002800286,"about_ca_topic_score_gemma":0.00009294764,"teacher_disagreement_score":0.11346707,"about_ca_system_score_codex":0.000032368236,"about_ca_system_score_gemma":0.00019018307,"threshold_uncertainty_score":0.99996316},"labels":[],"label_agreement":null},{"id":"W3005687190","doi":"10.1101/2020.02.07.939256","title":"Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Mental Health; School of Medicine, University of California, San Diego; University of California, San Diego","keywords":"Haploinsufficiency; RHOA; Neurogenesis; Biology; Cell biology; Mutant; Actin cytoskeleton; Phenotype; Cytoskeleton; Genetics; Signal transduction; Gene","score_opus":0.01080033193097076,"score_gpt":0.2545936524316545,"score_spread":0.24379332050068372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005687190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8973265,0.003722521,0.096970946,0.00040930626,0.00060062687,0.00049703184,0.0002819956,0.00018480177,0.0000062698696],"genre_scores_gemma":[0.9889435,0.0014195701,0.008467501,0.00033274866,0.00057447783,0.000054711203,0.000007705126,0.00019608186,0.0000037016428],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967328,0.00011021385,0.0006734388,0.0014118273,0.00034760294,0.00072414207],"domain_scores_gemma":[0.99808,0.0000373086,0.00025313935,0.00096514804,0.00019564485,0.00046877342],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028879376,0.0007443591,0.0006335282,0.00009975637,0.00019216533,0.0001831591,0.0004997699,0.00075626135,0.000014604881],"category_scores_gemma":[0.00034957624,0.0008313826,0.0002568433,0.00029819633,0.000184983,0.0000119227625,0.0009142449,0.00078322453,0.0000130128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042860007,0.00010462385,0.0016026874,0.00038370423,0.0001684294,0.000067187226,0.000013283265,0.0014076083,0.9957425,0.00040425884,0.00005723457,0.000005650835],"study_design_scores_gemma":[0.0011769527,0.000519367,0.055869784,0.00027775843,0.00044785498,7.3945114e-7,0.000012600107,0.041294686,0.89649403,0.000008760959,0.0018630015,0.0020344337],"about_ca_topic_score_codex":0.000031682586,"about_ca_topic_score_gemma":0.0000050282065,"teacher_disagreement_score":0.09924841,"about_ca_system_score_codex":0.00007937154,"about_ca_system_score_gemma":0.00039857143,"threshold_uncertainty_score":0.9994137},"labels":[],"label_agreement":null},{"id":"W3006056876","doi":"10.1101/2020.02.10.942672","title":"A Safe Harbor-Targeted CRISPR/Cas9 Homology Independent Targeted Integration (HITI) System for Multi-Modality Reporter Gene-Based Cell Tracking","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"CRISPR; Reporter gene; Cas9; Biology; Computational biology; Bioluminescence imaging; Gene; Genome editing; Gene targeting; Genetics; Luciferase; Gene expression; Transfection","score_opus":0.020224892961517447,"score_gpt":0.2687685165375579,"score_spread":0.24854362357604046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006056876","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40097734,0.0022081854,0.59198815,0.0001939692,0.0017314663,0.001808356,0.00079839485,0.0002888804,0.0000052705227],"genre_scores_gemma":[0.95688933,0.00006032395,0.040827353,0.00023948819,0.0008739906,0.00079535774,0.000047345915,0.0002603247,0.000006470577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99531007,0.00022869757,0.0012064218,0.0020134954,0.0003917724,0.0008495308],"domain_scores_gemma":[0.99627715,0.000037464742,0.0007641341,0.0016181027,0.00087351183,0.00042962967],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00079356454,0.0009653512,0.00092014833,0.00023424283,0.0002126578,0.0002051122,0.0006770395,0.0013806361,0.000012586421],"category_scores_gemma":[0.0003916018,0.0010900337,0.00053101126,0.00026673876,0.00009700907,0.000014638048,0.00038543533,0.00072907505,0.000011449124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021769936,0.00017343595,0.00094067695,0.0011364681,0.00022795219,0.000083896746,0.000014383535,0.002317046,0.99456704,0.000027165126,0.00028861404,0.0000056413223],"study_design_scores_gemma":[0.0016155784,0.00024242762,0.011925556,0.00018353695,0.00025989208,2.2941994e-7,0.00001310154,0.015582292,0.96706635,6.7311356e-7,0.0019897132,0.0011206528],"about_ca_topic_score_codex":0.00007004381,"about_ca_topic_score_gemma":0.000017483386,"teacher_disagreement_score":0.555912,"about_ca_system_score_codex":0.00028827984,"about_ca_system_score_gemma":0.00084121426,"threshold_uncertainty_score":0.9999158},"labels":[],"label_agreement":null},{"id":"W3006215407","doi":"10.1016/j.chom.2020.01.019","title":"In the Anti-CRISPR Jungle, Only the Weak Thrive?","year":2020,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Population Health Research Institute; McMaster University","funders":"Biotechnology and Biological Sciences Research Council; Natural Environment Research Council; Sight Research UK","keywords":"Biology; CRISPR; Context (archaeology); Jungle; Immune system; Microbiology; Genetics; Gene; Ecology","score_opus":0.006198892817872427,"score_gpt":0.24995848570112567,"score_spread":0.24375959288325325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006215407","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02697634,0.027754962,0.0026018023,0.9256142,0.0021789968,0.0014411926,0.00024656515,0.000046502613,0.013139451],"genre_scores_gemma":[0.10398958,0.0018343121,0.00021154628,0.87755513,0.0063059763,0.00003464863,0.000989436,0.00016517835,0.0089142155],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99846816,0.000109782115,0.0002730171,0.0005344826,0.00016269258,0.00045185207],"domain_scores_gemma":[0.99899995,0.000038828974,0.00008672952,0.00080586626,0.000034939378,0.00003371183],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012862941,0.00038241883,0.00026254967,0.00004074801,0.00009926697,0.00007876831,0.0010090419,0.0004807123,0.000056691242],"category_scores_gemma":[0.000021346803,0.00025153204,0.00022321143,0.00015164203,0.00011086727,0.000002051446,0.0002615827,0.0011699814,0.00011489035],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000030118001,0.0000142338085,0.000028010949,0.00006207202,0.000020425245,0.00006819789,0.00017932289,0.00001896755,0.27747753,0.0000016096816,0.7220621,0.000064491316],"study_design_scores_gemma":[0.00022634176,0.00006415993,0.00016054964,0.000021709875,0.000042549047,0.000047822014,0.000121887075,0.0000068262725,0.10365354,0.000007469483,0.895346,0.00030113623],"about_ca_topic_score_codex":0.00004828648,"about_ca_topic_score_gemma":0.00003815106,"teacher_disagreement_score":0.173824,"about_ca_system_score_codex":0.00001324849,"about_ca_system_score_gemma":0.00009793154,"threshold_uncertainty_score":0.9999937},"labels":[],"label_agreement":null},{"id":"W3006399675","doi":"10.1093/biomethods/bpaa003","title":"Genome editing in the nematode Caenorhabditis briggsae using the CRISPR/Cas9 system","year":2020,"lang":"en","type":"article","venue":"Biology Methods and Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Cas9; Biology; Genetics; Genome editing; Gene; Plasmid; Caenorhabditis elegans; Genome; Caenorhabditis","score_opus":0.058702267669735034,"score_gpt":0.4578715914963711,"score_spread":0.39916932382663606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006399675","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17607741,0.0029629574,0.78491235,0.001712796,0.0002137504,0.033212233,0.00003965971,0.000044425964,0.0008244065],"genre_scores_gemma":[0.91727495,0.00004572718,0.06272019,0.0014447119,0.0018297731,0.016602777,0.000028238914,0.000040397288,0.0000132212535],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984766,0.0006527013,0.0002520512,0.00031140767,0.000049159742,0.00025803412],"domain_scores_gemma":[0.9995044,0.000087184286,0.000074310614,0.00025205404,0.000027741946,0.00005429497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011853642,0.00015582243,0.0002000882,0.000018778926,0.00014094071,0.000038790324,0.00027052537,0.00015108094,0.0000049329715],"category_scores_gemma":[0.00015979231,0.00009402503,0.000059460166,0.000113146656,0.00009097659,0.0000025117358,0.00012689507,0.00016675198,9.612372e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004187462,0.00001117195,0.0028530434,0.00019912113,0.00003532654,0.000007878973,0.0006197235,0.00024828388,0.9873896,0.00059937395,0.00008023047,0.007914376],"study_design_scores_gemma":[0.0025273275,0.0015622649,0.01998258,0.00023643383,0.00011355454,0.0008087524,0.00610381,0.011878318,0.35756817,0.0004575502,0.5976089,0.0011522986],"about_ca_topic_score_codex":0.00003867785,"about_ca_topic_score_gemma":0.0000082610395,"teacher_disagreement_score":0.7411976,"about_ca_system_score_codex":0.000006939876,"about_ca_system_score_gemma":0.000029178984,"threshold_uncertainty_score":0.38342294},"labels":[],"label_agreement":null},{"id":"W3007329329","doi":"10.3389/fphar.2020.00119","title":"Synthetic Biology Speeds Up Drug Target Discovery","year":2020,"lang":"en","type":"review","venue":"Frontiers in Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Synthetic biology; Drug discovery; Electronic circuit; Drug; Computer science; Computational biology; Biology; Bioinformatics; Pharmacology; Engineering","score_opus":0.011978327427218138,"score_gpt":0.3498643674066688,"score_spread":0.33788603997945066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007329329","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000026640248,0.9722537,0.01716416,0.00008661403,0.009318409,0.00060606777,0.00014305292,0.000026416199,0.00037495702],"genre_scores_gemma":[0.00019485518,0.9945775,0.0019092272,0.00020489884,0.001183747,0.00016448874,0.00053445477,0.00010405843,0.001126759],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99746156,0.00031223075,0.00059509074,0.00089045294,0.00007742154,0.0006632222],"domain_scores_gemma":[0.9992764,0.000033450862,0.00017323265,0.00034583433,0.000021019507,0.00015007518],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023537088,0.00056035136,0.0014735862,0.00025197212,0.00004427127,0.000020852018,0.0006438427,0.00055504777,0.00006833051],"category_scores_gemma":[0.000051337774,0.00053901924,0.00043891766,0.00026908945,0.00016639431,0.000004476909,0.0003854416,0.0005489586,0.000032110907],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000754326,0.00009190578,0.000076921,0.0037998057,0.00089843245,0.000096950345,0.00006962252,0.00011616711,0.0018991978,0.000043429925,0.2714703,0.7213618],"study_design_scores_gemma":[0.00043536746,0.000084497624,8.0061113e-7,0.00022140653,0.0003612559,0.00004188149,0.000024452042,0.00007131905,0.001364929,0.000061272636,0.99680847,0.0005243548],"about_ca_topic_score_codex":0.000005070047,"about_ca_topic_score_gemma":0.0000018929434,"teacher_disagreement_score":0.72533816,"about_ca_system_score_codex":0.00008105538,"about_ca_system_score_gemma":0.0002704698,"threshold_uncertainty_score":0.99970615},"labels":[],"label_agreement":null},{"id":"W3007694854","doi":"10.1089/crispr.2020.29082.jco","title":"A Jumbo Formation in the Viral Game Plan","year":2020,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bausch Health (Canada); Université Laval","funders":"","keywords":"Plan (archaeology); Chemistry; Geography; Archaeology","score_opus":0.017424246613579157,"score_gpt":0.29330324947874337,"score_spread":0.2758790028651642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007694854","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9415485,0.0013004541,0.048240174,0.007816689,0.0001279964,0.00011966576,0.000003304543,0.000005767639,0.0008373942],"genre_scores_gemma":[0.9973481,0.00017711346,0.00008709272,0.0017765578,0.0005756904,0.0000034733669,0.000005639278,0.000006736587,0.000019570354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949473,0.000061427156,0.00013799338,0.00006414554,0.00010241849,0.00013930938],"domain_scores_gemma":[0.9997882,0.000008935891,0.000036102607,0.00011092957,0.000016117114,0.000039715716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023290535,0.0000672415,0.000054097298,0.000012678653,0.000066351335,0.00004938833,0.00025671127,0.000035175657,0.000014966422],"category_scores_gemma":[0.000045027005,0.00003799282,0.00005086602,0.000051879222,0.000018293296,0.000004073645,0.00003362688,0.00020665122,0.000010111103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023406495,0.000050896768,0.00087711884,0.00003579398,0.000055128352,0.000055251952,0.011796625,0.008439928,0.91441256,0.00028646036,0.05322554,0.010530643],"study_design_scores_gemma":[0.0030513979,0.0011834988,0.016638761,0.00005399424,0.00009091861,0.00322369,0.008792593,0.014719012,0.5239394,0.0012724883,0.42637095,0.0006633515],"about_ca_topic_score_codex":0.0000022430947,"about_ca_topic_score_gemma":0.0000067047677,"teacher_disagreement_score":0.39047322,"about_ca_system_score_codex":0.000004877969,"about_ca_system_score_gemma":0.000012591494,"threshold_uncertainty_score":0.15493023},"labels":[],"label_agreement":null},{"id":"W3007847401","doi":"10.1073/pnas.1903666117","title":"The size of the immune repertoire of bacteria","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft; Simons Foundation; National Science Foundation","keywords":"Biology; Archaea; CRISPR; Bacteria; Immune system; Acquired immune system; Repertoire; Genome; Genetics; Computational biology; Gene","score_opus":0.016399495430469764,"score_gpt":0.29362914296701986,"score_spread":0.2772296475365501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007847401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99319357,0.00067186315,0.0000020051732,0.0049709813,0.000021833446,0.00008174579,0.0000083562345,0.0000012611159,0.00104836],"genre_scores_gemma":[0.9993903,0.00008718467,0.00029517154,0.00009303913,0.000049149327,0.0000020520556,5.8848602e-8,0.0000022352542,0.000080828904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992644,0.000003747481,0.00022106712,0.000104307255,0.0003385662,0.000067876266],"domain_scores_gemma":[0.99956626,0.00003730042,0.00023215543,0.000012874535,0.00013839173,0.000013023716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039544515,0.000048418282,0.00007791894,0.000008461404,0.0000836544,0.0000050337812,0.0006923995,0.00004432821,0.0000032194407],"category_scores_gemma":[0.0008201973,0.00002396453,0.000080128375,0.00021405547,0.00049824436,0.000005373089,0.00019084285,0.000055029806,6.562416e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011525291,0.00000574234,0.0010500044,0.000029826195,0.00001088662,2.7282465e-10,0.0000755337,0.0000906295,0.9969171,0.0014159518,0.00020290197,0.00018985047],"study_design_scores_gemma":[0.000065928325,0.00003800119,0.044609446,0.000022792692,0.000005534782,0.0000011470931,0.0001193221,0.00016397334,0.9532615,0.0006215557,0.0010634839,0.00002729139],"about_ca_topic_score_codex":0.0000020218645,"about_ca_topic_score_gemma":4.4246182e-8,"teacher_disagreement_score":0.043655626,"about_ca_system_score_codex":0.0000023722166,"about_ca_system_score_gemma":0.000023284916,"threshold_uncertainty_score":0.18358022},"labels":[],"label_agreement":null},{"id":"W3008299308","doi":"10.1089/crispr.2019.0061","title":"CRISPR-Cas9 Application in Canadian Public and Private Plant Breeding","year":2020,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"CRISPR; Genome editing; Context (archaeology); Cas9; Biology; Biotechnology; Genetics","score_opus":0.025783534891670495,"score_gpt":0.32570386363042836,"score_spread":0.29992032873875785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008299308","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021997995,0.99519193,0.0031787127,0.0007123267,0.0001861179,0.00031481945,0.00003837073,0.000006203019,0.0001515377],"genre_scores_gemma":[0.009582637,0.9892244,0.00012258971,0.00011738571,0.0007759696,0.000029381425,0.00007469394,0.0000460741,0.00002687245],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986632,0.000088450885,0.00040458233,0.000282116,0.00011939543,0.0004422536],"domain_scores_gemma":[0.9991671,0.000020155469,0.00015177534,0.0002538356,0.00003141207,0.0003757564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051193236,0.00027274748,0.00045603074,0.00015609075,0.00017313288,0.00014204643,0.00041844096,0.00022900836,0.000009191522],"category_scores_gemma":[0.000098684184,0.00019826337,0.00013935124,0.00017069663,0.00004083712,0.0000045079523,0.00011857245,0.0006206819,0.000009609025],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007755195,0.000013921415,0.00021179963,0.0013113609,0.00019071558,0.000068097965,0.00011855202,0.000014008662,0.000811945,0.00039104343,0.0039380714,0.9929227],"study_design_scores_gemma":[0.00011521018,0.00004263618,0.00003172841,0.00040446632,0.00009408918,0.0009686481,0.000028767357,0.000084598134,0.00009051859,0.000030067225,0.9978847,0.00022455661],"about_ca_topic_score_codex":0.0010224016,"about_ca_topic_score_gemma":0.007263179,"teacher_disagreement_score":0.9939467,"about_ca_system_score_codex":0.00008457217,"about_ca_system_score_gemma":0.00042326204,"threshold_uncertainty_score":0.80849457},"labels":[],"label_agreement":null},{"id":"W3008338337","doi":"10.1101/2020.02.23.959932","title":"Specialized DNA structures act as genomic beacons for integration by evolutionarily diverse retroviruses","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Provirus; Genome; Genetics; DNA; Retrovirus; Integrase; Gene; Computational biology","score_opus":0.012708497332858747,"score_gpt":0.26095214102292247,"score_spread":0.24824364369006371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008338337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93904006,0.0028491858,0.053380627,0.0003155306,0.0015136012,0.0011008473,0.0016391084,0.00014706877,0.000013947105],"genre_scores_gemma":[0.99022776,0.00048247908,0.007150344,0.0003987742,0.0014266503,0.00015528972,0.000026534652,0.000120620796,0.000011521817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980137,0.000053131695,0.00038795557,0.0009508598,0.00019982597,0.00039455688],"domain_scores_gemma":[0.9985722,0.000025763457,0.00022599664,0.0007073642,0.00024513566,0.00022359098],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015311617,0.0005007698,0.00040136807,0.00009117043,0.00014937014,0.00012812926,0.00045506773,0.00059356133,0.00003326528],"category_scores_gemma":[0.00044438726,0.000561485,0.00025365534,0.00011600359,0.000088253044,0.000007921527,0.00039173706,0.0003354265,0.000014316629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012548326,0.000028406548,0.00047601585,0.00010178998,0.00018442936,0.0000030041863,0.00000775557,0.00014800687,0.9864057,0.00024280435,0.012270222,0.000006438226],"study_design_scores_gemma":[0.0006825695,0.00015074064,0.011223101,0.00004482487,0.00014367126,2.8030197e-8,0.000007310038,0.00016728767,0.9162357,0.000015503034,0.07067283,0.0006564652],"about_ca_topic_score_codex":0.000048034304,"about_ca_topic_score_gemma":0.0000071318314,"teacher_disagreement_score":0.07016998,"about_ca_system_score_codex":0.00013048369,"about_ca_system_score_gemma":0.00036648908,"threshold_uncertainty_score":0.9996837},"labels":[],"label_agreement":null},{"id":"W3008790069","doi":"10.1016/j.ibmb.2020.103336","title":"Spatial and temporal control of gene manipulation in Drosophila via drug-activated Cas9 nucleases","year":2020,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Cas9; Biology; Genome editing; Computational biology; Gene; RNA interference; Genetics; Cell biology; RNA","score_opus":0.007632810731540084,"score_gpt":0.26003387839601333,"score_spread":0.25240106766447323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008790069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705266,0.0018774684,0.027130725,0.00021631551,0.000028658933,0.00013238634,0.000036573038,0.000009795807,0.0000414928],"genre_scores_gemma":[0.9989613,0.00008276433,0.00039449983,0.0002654461,0.00008885506,0.000008651047,0.00017754133,0.000016967657,0.000003933209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991556,0.00004125141,0.00022540874,0.00036390306,0.000044050375,0.00016979108],"domain_scores_gemma":[0.9996499,0.000009612879,0.000068821224,0.00013873742,0.000032277738,0.00010065269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058969657,0.00016995236,0.00020951887,0.000027846128,0.000023136357,0.000006694821,0.00007514075,0.00019614013,0.000005576147],"category_scores_gemma":[0.000062904524,0.00017919207,0.000044634617,0.00006610752,0.00011416172,0.000002164059,0.000059153146,0.000086795204,2.94566e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017747692,0.000023854745,0.01242032,0.000060194627,0.000037392852,0.000012864174,0.000038690167,0.000071423165,0.98612916,0.000011002633,0.000008414308,0.0010092178],"study_design_scores_gemma":[0.0010434645,0.00020722809,0.0034420143,0.000010168491,0.000017246652,0.000036027053,0.0000180578,0.00090750074,0.993866,0.000043188164,0.00022356704,0.00018548217],"about_ca_topic_score_codex":0.00013212988,"about_ca_topic_score_gemma":0.00001169033,"teacher_disagreement_score":0.028434757,"about_ca_system_score_codex":0.000005120208,"about_ca_system_score_gemma":0.000025485955,"threshold_uncertainty_score":0.73072404},"labels":[],"label_agreement":null},{"id":"W3009870983","doi":"10.1158/1538-7445.sabcs19-p1-03-11","title":"Abstract P1-03-11: In vivo rapid discovery of tumor suppressors in breast cancer","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Cancer; Biology; Cancer research; Suppressor; Breast cancer; Tumor suppressor gene; Epigenetics; Mammary tumor; Gene; Mutation; Cancer cell; Genetics; Carcinogenesis","score_opus":0.028312452657892426,"score_gpt":0.375782520404754,"score_spread":0.34747006774686157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3009870983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995151,0.0031558704,0.000022887703,0.00093507307,0.000064997206,0.00017558996,0.00020186987,0.0000034762554,0.00028924242],"genre_scores_gemma":[0.9980742,0.0014021643,0.000016630722,0.000077356955,0.00021075016,0.00009358703,0.000008841515,0.000021534279,0.00009498242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988683,0.00004007033,0.00020245259,0.00031041872,0.00021985565,0.00035889487],"domain_scores_gemma":[0.9996223,0.000019886875,0.000024078532,0.00019082798,0.000056859495,0.00008604958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022240786,0.00010155475,0.00015874549,0.000085552056,0.000016956003,0.00001746704,0.00024044266,0.00006815115,0.00029868446],"category_scores_gemma":[0.00004287686,0.000099817196,0.00004605377,0.00028262145,0.000084845095,0.0000070518854,0.00013547683,0.00021256595,0.0000020944356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014366626,0.000033683078,0.03101488,0.0001595077,0.000011988281,0.000013996406,0.0001700043,0.003897129,0.9610213,0.000006418493,0.0027127566,0.0008146568],"study_design_scores_gemma":[0.0006127212,0.000050148843,0.07182303,0.00009719144,0.0000021378005,0.00000176924,0.00025316802,0.00016031261,0.9215719,0.000005232474,0.0052894047,0.00013297296],"about_ca_topic_score_codex":0.0022338042,"about_ca_topic_score_gemma":0.0021336237,"teacher_disagreement_score":0.04080815,"about_ca_system_score_codex":0.000043699514,"about_ca_system_score_gemma":0.00020188154,"threshold_uncertainty_score":0.4070427},"labels":[],"label_agreement":null},{"id":"W3011051523","doi":"10.1016/j.omtm.2020.03.002","title":"Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Health Canada; Canada Foundation for Innovation; Canadian Bee Research Fund; Fondation Brain Canada","keywords":"CRISPR; Aniridia; Germline; Genome editing; Genetics; Biology; Cas9; PAX6; Gene; Transcription factor","score_opus":0.06213300370558905,"score_gpt":0.4431595171498262,"score_spread":0.38102651344423716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011051523","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4968803,0.0006001096,0.5020005,0.00017000195,0.000083532075,0.0002244719,0.000011478893,0.000013988048,0.000015643078],"genre_scores_gemma":[0.47399238,0.0005370872,0.5240727,0.0010567294,0.00010935987,0.000032960656,0.00010280974,0.000054877135,0.000041063904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971141,0.0003067316,0.0012098321,0.0007008187,0.00028085342,0.0003876692],"domain_scores_gemma":[0.9989518,0.000088571265,0.00021801663,0.00038194755,0.00011147339,0.00024821426],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016680718,0.00031583995,0.00052423234,0.000065918895,0.000035108096,0.000014355465,0.00036199726,0.0003097144,0.000012007794],"category_scores_gemma":[0.00061561016,0.00031084684,0.00021922818,0.00021578194,0.00007367705,0.0000055582695,0.00024564506,0.00028007527,0.0000040817768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022014431,0.00029972478,0.0010844619,0.00003373025,0.00012428877,0.0000075813846,0.0002925234,0.00836423,0.96055996,0.000005541494,0.000028502738,0.02897931],"study_design_scores_gemma":[0.002333987,0.00030747888,0.0019322137,0.000029823941,0.000012327579,0.000002066352,0.00001880108,0.018615035,0.9729063,0.00002992365,0.0034716122,0.00034041386],"about_ca_topic_score_codex":0.000004026804,"about_ca_topic_score_gemma":0.0000024261622,"teacher_disagreement_score":0.028638897,"about_ca_system_score_codex":0.000025382089,"about_ca_system_score_gemma":0.00025603457,"threshold_uncertainty_score":0.9999344},"labels":[],"label_agreement":null},{"id":"W3011345444","doi":"10.1038/s41587-020-0437-z","title":"Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform","year":2020,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"Canada First Research Excellence Fund; European Molecular Biology Organization; Canada Excellence Research Chairs, Government of Canada; Government of Canada; Canadian Institutes of Health Research; Genome Canada; Foundation for the National Institutes of Health","keywords":"Functional genomics; Computational biology; CRISPR; Exon; Cas9; Genomics; Genetics; Biology; Genome editing; Genome; Gene","score_opus":0.008705699584421434,"score_gpt":0.23459781235384217,"score_spread":0.22589211276942073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011345444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8944297,0.0029450832,0.10065212,0.0014875412,0.00017217972,0.00014557724,0.000011711951,0.00006500799,0.00009107218],"genre_scores_gemma":[0.99278104,0.00035538836,0.005984822,0.0004714053,0.00029603968,0.000010603799,0.000053863878,0.000021784408,0.000025042502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921924,0.0000063876896,0.00012803273,0.00038059728,0.000070721384,0.00019502534],"domain_scores_gemma":[0.9996741,0.000006278586,0.000048751077,0.00017159562,0.000034826448,0.000064456726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003307958,0.00015315675,0.000117394244,0.000071784896,0.00006346461,0.000015129287,0.00009092093,0.00049962173,0.000008510744],"category_scores_gemma":[0.000043361357,0.00014389587,0.00003166962,0.00010379199,0.00007070608,0.0000041481608,0.00010694451,0.00043368046,0.000004795351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001752,0.00001385094,0.0004893453,0.000033485663,0.00007233253,0.000018499271,0.000037505735,0.0013062753,0.98430055,0.0001812802,0.0010439644,0.01232773],"study_design_scores_gemma":[0.0010722583,0.0007567501,0.0069085495,0.000020764764,0.000039517578,0.0010703612,0.00026272002,0.008227671,0.7375368,0.00006693239,0.24359144,0.0004462727],"about_ca_topic_score_codex":0.0000048869692,"about_ca_topic_score_gemma":0.000017565926,"teacher_disagreement_score":0.24676377,"about_ca_system_score_codex":0.000021153855,"about_ca_system_score_gemma":0.000032186123,"threshold_uncertainty_score":0.5867903},"labels":[],"label_agreement":null},{"id":"W3011385598","doi":"10.1111/jwip.12151","title":"Implications of biological information digitization: Access and benefit sharing of plant genetic resources","year":2020,"lang":"en","type":"article","venue":"The Journal of World Intellectual Property","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Saskatchewan","funders":"","keywords":"Digitization; Genetic resources; Intellectual property; Transformative learning; Decoupling (probability); Corporate governance; Knowledge management; Value (mathematics); Information sharing; Business; Computer science; World Wide Web; Sociology; Biotechnology; Engineering; Telecommunications; Biology","score_opus":0.03582075193752477,"score_gpt":0.27939632411110343,"score_spread":0.24357557217357867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011385598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786284,0.000998613,0.018761642,0.00063677994,0.000025941752,0.000110020774,0.00001563839,0.000002898259,0.0008200757],"genre_scores_gemma":[0.99880135,0.00072419556,0.00021273227,0.0001379235,0.00007087367,9.205482e-7,0.0000062824947,0.0000040415584,0.00004169787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946254,0.00001089247,0.00034333952,0.000050470677,0.000067563175,0.00006516271],"domain_scores_gemma":[0.9995401,0.000038200906,0.00016323489,0.0000902741,0.00012647531,0.00004174979],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010681923,0.00006305635,0.00011540016,0.00004301766,0.000030692947,0.000016078684,0.00026141104,0.000027025588,0.000026769645],"category_scores_gemma":[0.0001841083,0.00003211396,0.000036007285,0.00012899417,0.00006402085,0.000011033473,0.00014708616,0.000068623944,4.2587797e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014988852,0.00009354818,0.018741747,0.00026222228,0.0003293683,7.4600666e-7,0.009875067,0.030358931,0.8908322,0.0002184752,0.0062063313,0.04158247],"study_design_scores_gemma":[0.00086972874,0.0019685088,0.042851437,0.00016072013,0.000111963964,0.00019004678,0.0006798082,0.005719862,0.8805227,0.0006305645,0.065994814,0.0002998364],"about_ca_topic_score_codex":0.000005055957,"about_ca_topic_score_gemma":0.0000044309336,"teacher_disagreement_score":0.059788484,"about_ca_system_score_codex":0.0000031075426,"about_ca_system_score_gemma":0.000012691634,"threshold_uncertainty_score":0.13095692},"labels":[],"label_agreement":null},{"id":"W3011435240","doi":"10.1146/annurev-biochem-011420-111224","title":"Anti-CRISPRs: Protein Inhibitors of CRISPR-Cas Systems","year":2020,"lang":"en","type":"review","venue":"Annual Review of Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"CRISPR; Biology; Computational biology; Genome; Genome editing; Palindrome; Mobile genetic elements; Archaea; Genetics; CRISPR interference; Trans-activating crRNA; Gene","score_opus":0.01046891227442831,"score_gpt":0.3417960559500767,"score_spread":0.3313271436756484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011435240","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003695837,0.99717647,0.00032378157,0.000025273097,0.00018462319,0.0011153031,0.0006753748,0.000016463231,0.00044577153],"genre_scores_gemma":[0.0007440435,0.99736,0.00017620572,0.000031041494,0.0005383549,0.0001362219,0.0006697698,0.00008992771,0.00025441512],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969785,0.000097664866,0.0015493715,0.0006948952,0.00035546644,0.0003240605],"domain_scores_gemma":[0.9976492,0.000022612352,0.0009212581,0.00093357626,0.00028937843,0.00018400738],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034224463,0.0006309213,0.002553083,0.000054092176,0.000023754174,0.00001078564,0.00064075436,0.0005618805,0.000016525071],"category_scores_gemma":[0.0004937469,0.0005551491,0.0010182463,0.0003443572,0.00012592724,0.0000035528335,0.00031748827,0.00030841748,0.000011762815],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000052010078,0.00007656436,0.0000013151325,0.7567347,0.0004007206,0.000012720927,0.000014729317,0.000001339502,0.023724375,0.0000074139157,0.0123090055,0.20671189],"study_design_scores_gemma":[0.000078215475,0.000097000666,1.4820355e-7,0.113748536,0.0004329427,0.000047191566,0.00003106768,5.477041e-7,0.15828611,3.4426722e-7,0.72690994,0.0003679494],"about_ca_topic_score_codex":0.000012217119,"about_ca_topic_score_gemma":1.6321414e-7,"teacher_disagreement_score":0.7146009,"about_ca_system_score_codex":0.000027147249,"about_ca_system_score_gemma":0.00044997758,"threshold_uncertainty_score":0.99969},"labels":[],"label_agreement":null},{"id":"W3012000879","doi":"10.1101/2020.03.20.984476","title":"The pathognomonic FOXL2 C134W mutation alters DNA binding specificity","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Terry Fox Research Institute","keywords":"Biology; Missense mutation; Genetics; Somatic cell; Mutation; Transcription factor; Transcriptome; Point mutation; Computational biology; Cell biology; Molecular biology; Gene; Gene expression","score_opus":0.011470567736201764,"score_gpt":0.24508724945512037,"score_spread":0.2336166817189186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012000879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97722197,0.0023013998,0.017545626,0.00038419376,0.001633262,0.0005986504,0.0001554958,0.0001413309,0.000018089491],"genre_scores_gemma":[0.99583244,0.0010016705,0.0017388808,0.00011762576,0.0010518426,0.00011658837,0.0000036170677,0.00012738512,0.000009975025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767977,0.00009785847,0.00045299498,0.00095356687,0.00027921214,0.00053660007],"domain_scores_gemma":[0.9982287,0.000036410558,0.0002502969,0.0010650358,0.0001857487,0.00023380837],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004223536,0.0004879288,0.0003148652,0.00007470955,0.00027210684,0.00023927754,0.0006241017,0.00043211668,0.000007622419],"category_scores_gemma":[0.0002375929,0.00046602904,0.00022116004,0.00021835738,0.00010195394,0.000005915331,0.0005758636,0.0005263488,0.00004428174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034884397,0.00002334061,0.000543412,0.00010383968,0.00013107684,0.00002739041,0.000007930216,0.00040991177,0.99800426,0.00009392405,0.0006066423,0.000013364026],"study_design_scores_gemma":[0.00031396025,0.00008733175,0.013997558,0.00008792971,0.00007885808,6.091276e-8,0.000010754378,0.0007564212,0.9640167,0.0000025242161,0.019984609,0.00066334376],"about_ca_topic_score_codex":0.000010413688,"about_ca_topic_score_gemma":0.000004805948,"teacher_disagreement_score":0.033987634,"about_ca_system_score_codex":0.0000902378,"about_ca_system_score_gemma":0.00027345002,"threshold_uncertainty_score":0.99977916},"labels":[],"label_agreement":null},{"id":"W3012015863","doi":"10.1158/1535-7163.targ-19-pl03-03","title":"Abstract PL03-03: Navigating gene-gene and drug-gene interaction landscapes underpinning the DNA damage response","year":2019,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Gene; Genome; Computational biology; Genome editing; Biology; Cancer; Drug response; Human genome; CRISPR; DNA; Genetics; Drug; Pharmacology","score_opus":0.011009322859606855,"score_gpt":0.30987547611098887,"score_spread":0.298866153251382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012015863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871757,0.009066933,0.0023875935,0.00067091145,0.00030684864,0.00023148536,0.00001763501,0.000023960529,0.00011894586],"genre_scores_gemma":[0.99719656,0.0009207493,0.00053775124,0.0009240772,0.00015065674,0.000028654536,0.00005090096,0.00005851925,0.00013210635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988557,0.000086273016,0.00021678608,0.00037610132,0.00016991024,0.00029523027],"domain_scores_gemma":[0.99931186,0.00004040526,0.00009153282,0.00043542587,0.00005857672,0.00006222039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003071671,0.0002330489,0.00015380952,0.000030918523,0.00011566481,0.000076221746,0.00019859256,0.000117110554,0.000020916586],"category_scores_gemma":[0.000012681937,0.00019859157,0.000088154695,0.000100686986,0.00004202572,0.0000072414473,0.00010917729,0.00023630468,0.000008257973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018547942,0.000013998934,0.00090179435,0.000019120256,0.00015069166,0.000006709068,0.0004946153,0.006792306,0.98614633,0.0000057700518,0.000016775577,0.0052664336],"study_design_scores_gemma":[0.00051006663,0.00007682138,0.0057687173,0.00004388212,0.000054161825,0.000021523027,0.00035279396,0.0011739914,0.9801754,0.00001920068,0.011530848,0.00027260432],"about_ca_topic_score_codex":0.000050325118,"about_ca_topic_score_gemma":0.000038388695,"teacher_disagreement_score":0.011514073,"about_ca_system_score_codex":0.00003182054,"about_ca_system_score_gemma":0.000060474722,"threshold_uncertainty_score":0.80983293},"labels":[],"label_agreement":null},{"id":"W3012016445","doi":"10.1038/s41587-020-0455-x","title":"Prime genome editing in rice and wheat","year":2020,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":869,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute of Biomedical Imaging and Bioengineering; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Genome; Biology; Genome editing; Prime (order theory); Biotechnology; Computational biology; Genetics; Agronomy; Gene; Mathematics","score_opus":0.003448776320369736,"score_gpt":0.24945437264130488,"score_spread":0.24600559632093513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012016445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9744581,0.0130909085,0.0042473855,0.007457628,0.00013651658,0.00013591349,0.000007980954,0.00006300599,0.0004025574],"genre_scores_gemma":[0.9969984,0.00036814788,0.0016271174,0.000685727,0.0002606838,0.0000043329264,0.000016856857,0.000013105782,0.00002561704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993749,0.000008372994,0.00009874707,0.0002974194,0.000041573323,0.00017897782],"domain_scores_gemma":[0.9997758,0.0000042094075,0.000019649611,0.00014318783,0.000012198417,0.000044951084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004881252,0.000099226236,0.00010465735,0.00005012242,0.000019100713,0.0000061710275,0.00012454894,0.0007821899,0.0000037938114],"category_scores_gemma":[0.000121422825,0.00010126671,0.000019870624,0.00013435571,0.000044268112,0.0000012793927,0.00014422102,0.0004099417,0.0000032745058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001026562,0.0000055182363,0.000447955,0.000015659187,0.0000075400217,0.0000068488794,0.000023678544,0.000019571224,0.9969016,0.00014276186,0.0001494386,0.0022691994],"study_design_scores_gemma":[0.0003771174,0.00016451863,0.0045589996,0.0000056373174,0.000005284187,0.00003099902,0.00006355844,0.00018151218,0.9071047,0.00003419056,0.08731399,0.00015952424],"about_ca_topic_score_codex":0.0000027364035,"about_ca_topic_score_gemma":0.000009064352,"teacher_disagreement_score":0.08979689,"about_ca_system_score_codex":0.000005262599,"about_ca_system_score_gemma":0.000010911555,"threshold_uncertainty_score":0.6032965},"labels":[],"label_agreement":null},{"id":"W3012066364","doi":"10.1146/annurev-genom-121119-100145","title":"Models of Technology Transfer for Genome-Editing Technologies","year":2020,"lang":"en","type":"review","venue":"Annual Review of Genomics and Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wageningen University and Research; Corteva Agriscience; Göteborgs Universitet; Broad Institute; Iowa State University; Queensland University of Technology; University of Tasmania; Colorado State University; Simon Fraser University; U.S. Department of Agriculture","keywords":"Zinc finger nuclease; Transcription activator-like effector nuclease; Genome editing; Commercialization; Technology transfer; Genome; Biology; Business; Computer science; Knowledge management; Marketing; Genetics","score_opus":0.020551060992429798,"score_gpt":0.33203318815455235,"score_spread":0.31148212716212254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012066364","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009799217,0.9906666,0.007126946,0.000045257166,0.00005000671,0.0011286164,0.0007865788,0.00001862749,0.000079331665],"genre_scores_gemma":[0.0004458725,0.99538815,0.0035046549,0.000026792852,0.00013086181,0.00010704981,0.00029221375,0.00007994474,0.000024465075],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981446,0.000020412372,0.0009857694,0.00048955885,0.000095985924,0.000263674],"domain_scores_gemma":[0.9989634,0.000017302593,0.0002810566,0.00049056584,0.000194334,0.000053322285],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020076832,0.00040464845,0.0016369511,0.00015181229,0.000053515047,0.0000072887015,0.00049034646,0.00046074248,0.0000021090068],"category_scores_gemma":[0.00005398081,0.000380316,0.00046493366,0.00015967875,0.00019443629,0.0000022088038,0.0002737028,0.00017252773,4.4943192e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000032422747,0.000026782242,7.811662e-7,0.13323523,0.00028964473,9.848916e-7,0.000048191538,0.000023873135,0.0022723684,0.0013623021,0.00015348272,0.8625831],"study_design_scores_gemma":[0.0001413317,0.00046672305,2.873444e-7,0.008341659,0.0006902387,0.000017674018,0.000092521994,0.000011331574,0.001495977,0.00030166333,0.9881125,0.0003280909],"about_ca_topic_score_codex":8.3717214e-7,"about_ca_topic_score_gemma":0.0000020819466,"teacher_disagreement_score":0.987959,"about_ca_system_score_codex":0.00001305377,"about_ca_system_score_gemma":0.00012733012,"threshold_uncertainty_score":0.9998649},"labels":[],"label_agreement":null},{"id":"W3012393243","doi":"10.3390/genes11030342","title":"CRISPR-Generated Animal Models of Duchenne Muscular Dystrophy","year":2020,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Muscular Dystrophy Canada; Canadian Institutes of Health Research; Women and Children's Health Research Institute","keywords":"CRISPR; Duchenne muscular dystrophy; Dystrophin; Genome editing; Muscular dystrophy; Neuromuscular disease; Computational biology; Medicine; Animal model; Disease; Biology; Bioinformatics; Genetics; Gene; Pathology","score_opus":0.027123886468309183,"score_gpt":0.32675865697275547,"score_spread":0.2996347705044463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012393243","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00043748887,0.99107033,0.007733896,0.000009218129,0.00018777231,0.00029920498,0.00013240316,0.000020438543,0.00010924821],"genre_scores_gemma":[0.0015096208,0.9954159,0.0017265651,0.00001384111,0.0006189958,0.000049381495,0.00047764985,0.00008919232,0.00009881243],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985182,0.0000621331,0.00047735425,0.0005299401,0.00014146478,0.00027088006],"domain_scores_gemma":[0.9991355,0.0000065940276,0.00015368509,0.0004904264,0.00009293157,0.00012084383],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007629886,0.0004135338,0.00095659663,0.00006824166,0.000031928408,0.00001696456,0.00033653466,0.0003735275,0.00001667075],"category_scores_gemma":[0.000023441722,0.00037488423,0.00053320325,0.00018636892,0.00004271027,0.0000020034731,0.00018733513,0.00013415278,0.000012313732],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028745486,0.00006134789,0.0000015216948,0.010323743,0.00089371786,0.000033986966,0.000030690004,0.0023590226,0.09343999,0.00009824337,0.0015016304,0.89122736],"study_design_scores_gemma":[0.00013259008,0.00018028663,7.0130477e-7,0.00035354763,0.00039471278,0.000030211886,0.0000071034447,0.00024361927,0.020068074,0.000006900472,0.978202,0.00038024937],"about_ca_topic_score_codex":0.000010946804,"about_ca_topic_score_gemma":0.0000023984592,"teacher_disagreement_score":0.97670037,"about_ca_system_score_codex":0.0000116743895,"about_ca_system_score_gemma":0.00016428316,"threshold_uncertainty_score":0.9998703},"labels":[],"label_agreement":null},{"id":"W3013133988","doi":"10.1158/2326-6074.tumimm19-b16","title":"Abstract B16: Identification of tumor-specific antigens shared by induced pluripotent stem cells","year":2020,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Induced pluripotent stem cell; Cancer stem cell; Cancer immunotherapy; Biology; Stem cell; Cancer research; Embryonic stem cell; Cancer; Immunotherapy; Antigen; Immunology; Cell biology; Genetics; Gene","score_opus":0.0569917876543167,"score_gpt":0.3631866938506854,"score_spread":0.3061949061963687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013133988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825458,0.015891165,0.0004566552,0.00044780414,0.00020545645,0.00024953356,0.00010258002,0.000012645497,0.000088350615],"genre_scores_gemma":[0.9968737,0.0026186896,0.000024633602,0.000039485014,0.00012641781,0.000055180077,0.000056746285,0.000025529964,0.00017965934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998657,0.00006720613,0.00031686656,0.00040405677,0.00020074614,0.00035413873],"domain_scores_gemma":[0.9992195,0.000018224622,0.000075164004,0.00036647017,0.00024014004,0.00008052952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002456958,0.00011973552,0.00016717,0.000060864124,0.00007391494,0.000022415164,0.0003841537,0.00014522413,0.00009804914],"category_scores_gemma":[0.000023859515,0.0001269875,0.000063767635,0.00021255034,0.00013706433,0.000004313516,0.0001597449,0.00028751223,0.00003662466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102553226,0.000030257586,0.00034083356,0.000046444064,0.00007338617,0.00000298677,0.00015564196,0.00011022921,0.9881442,0.000006458017,0.006711107,0.004275908],"study_design_scores_gemma":[0.00033769954,0.00015899802,0.0058575743,0.0000132517525,0.000003755182,0.0000017400962,0.00033369404,0.000045427634,0.9710982,0.000003253509,0.022031873,0.0001145209],"about_ca_topic_score_codex":0.0000432006,"about_ca_topic_score_gemma":0.0000048074935,"teacher_disagreement_score":0.017045982,"about_ca_system_score_codex":0.000030284371,"about_ca_system_score_gemma":0.00010614931,"threshold_uncertainty_score":0.51784},"labels":[],"label_agreement":null},{"id":"W3013139933","doi":"10.1101/2020.03.28.012518","title":"Unraveling the functional role of DNA methylation using targeted DNA demethylation by steric blockage of DNA methyltransferase with CRISPR/dCas9","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"DNA methylation; Biology; DNA demethylation; Promoter; RNA-Directed DNA Methylation; Methylation; Epigenetics of physical exercise; Genetics; Regulation of gene expression; Gene; DNA; Gene expression; Epigenetics; Molecular biology","score_opus":0.011718237382730064,"score_gpt":0.2367992597872923,"score_spread":0.22508102240456224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013139933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7693844,0.003238347,0.22636561,0.000052118354,0.00020249936,0.0004623567,0.00025637695,0.000035243622,0.000003053424],"genre_scores_gemma":[0.9917756,0.00017250878,0.0075604776,0.000047604775,0.00027322033,0.000045689467,0.000013652822,0.00010985525,0.0000013961293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976456,0.00018008437,0.0006729737,0.000744908,0.00042333064,0.0003330608],"domain_scores_gemma":[0.99811214,0.000048918173,0.00043639672,0.0007503774,0.0005137665,0.00013841852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049980736,0.00048149083,0.00050585746,0.00013932328,0.000111282185,0.000042974705,0.00033536094,0.00043661156,0.000018886543],"category_scores_gemma":[0.00013530772,0.00043527185,0.00019112448,0.00043112866,0.00011769666,0.000012874313,0.00019796319,0.00038612031,0.0000011336647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012924241,0.0000569021,0.00089942187,0.00023332273,0.00040631412,0.0000016251898,0.000028088254,0.010433107,0.9877525,0.000024932651,0.0000256276,0.000008929394],"study_design_scores_gemma":[0.0004896689,0.00014211323,0.008787027,0.00010977826,0.00035379647,5.530745e-8,0.000023933084,0.004942059,0.9841969,0.0000025923696,0.0005020055,0.00045008791],"about_ca_topic_score_codex":0.000048068367,"about_ca_topic_score_gemma":0.0000035078344,"teacher_disagreement_score":0.2223912,"about_ca_system_score_codex":0.00005143842,"about_ca_system_score_gemma":0.00034691836,"threshold_uncertainty_score":0.9998099},"labels":[],"label_agreement":null},{"id":"W3013205857","doi":"10.1101/2020.03.25.008276","title":"Self-cutting and integrating CRISPR plasmids (SCIPs) enable targeted genomic integration of genetic payloads for rapid cell engineering","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; National Research Council Canada","funders":"","keywords":"CRISPR; Genome editing; Biology; Plasmid; Genome engineering; Cas9; Computational biology; Gene; Genetics; Insert (composites); Gene targeting","score_opus":0.006642081482396149,"score_gpt":0.21920276211516718,"score_spread":0.21256068063277103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013205857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8021364,0.0053688246,0.19057037,0.000044540764,0.0005908554,0.0009217959,0.00022086804,0.00013925481,0.000007063894],"genre_scores_gemma":[0.8527498,0.0006421362,0.14572236,0.000041564595,0.0005098949,0.00017535189,0.000005942236,0.00015063869,0.0000022657123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975923,0.000050101477,0.00070470385,0.0009735807,0.00017895609,0.00050036487],"domain_scores_gemma":[0.99842256,0.00005034562,0.0003506736,0.0006374468,0.00031333222,0.0002256585],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035419717,0.0005961069,0.00056331576,0.00017308464,0.000099330304,0.000108762964,0.00037766996,0.00054689776,0.0000063498305],"category_scores_gemma":[0.00029759872,0.00066674873,0.00019697558,0.00019077485,0.000046577872,0.000010123518,0.00046046227,0.0004431157,0.0000017953452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034218774,0.000039458653,0.000571489,0.0013147687,0.0001401101,0.000003186522,0.00004238058,0.0026094145,0.9950913,0.00003732993,0.000100714824,0.000015627658],"study_design_scores_gemma":[0.0005581341,0.00022157512,0.002679126,0.00017290168,0.000148432,6.295432e-8,0.000018950515,0.037171092,0.95537406,0.0000013844168,0.0030115303,0.0006427483],"about_ca_topic_score_codex":0.000017953635,"about_ca_topic_score_gemma":0.0000013586392,"teacher_disagreement_score":0.05061341,"about_ca_system_score_codex":0.00007257065,"about_ca_system_score_gemma":0.00026572825,"threshold_uncertainty_score":0.99957836},"labels":[],"label_agreement":null},{"id":"W3013547549","doi":"10.1016/j.jglr.2020.03.010","title":"Applying functional genomics to the study of lamprey development and sea lamprey population control","year":2020,"lang":"en","type":"article","venue":"Journal of Great Lakes Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Great Lakes Fishery Commission","keywords":"Lamprey; Petromyzon; Biology; CRISPR; Cas9; Genome editing; Evolutionary biology; Genomics; Organism; Ecology; Population; Model organism; Genome; Fishery; Gene; Genetics","score_opus":0.04782793723049053,"score_gpt":0.3447147457635732,"score_spread":0.2968868085330827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013547549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927397,0.0004177417,0.006097251,0.00032235368,0.000042091047,0.00033628504,0.00000291432,0.0000011688136,0.000040513463],"genre_scores_gemma":[0.9992025,0.000029264304,0.0003808278,0.000052265557,0.00025524432,0.00001656912,0.0000036491792,0.000008302197,0.000051365485],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99915916,0.00007199339,0.00023121022,0.00010584432,0.00030746768,0.00012430553],"domain_scores_gemma":[0.99951565,0.000032838856,0.000049163158,0.0000871931,0.00021633845,0.00009883883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005624759,0.00006066128,0.00011410868,0.000055138305,0.00008466655,0.000022556975,0.000121366276,0.000034871635,0.0000060263997],"category_scores_gemma":[0.00013146573,0.000043276614,0.000028147937,0.00009712892,0.000015229985,0.000003079087,0.00007684069,0.00013984425,9.830637e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016511235,0.00019758931,0.21325073,0.00009546617,0.00048448937,0.000017064709,0.005151106,0.051358715,0.6790269,0.000017271046,0.002400379,0.046349183],"study_design_scores_gemma":[0.0060095442,0.0051901178,0.66353863,0.00006678244,0.000088114684,0.000109073284,0.0067886743,0.003453816,0.1390469,0.000026363856,0.17528677,0.00039522245],"about_ca_topic_score_codex":0.000009726428,"about_ca_topic_score_gemma":0.0000794498,"teacher_disagreement_score":0.53998,"about_ca_system_score_codex":0.000015530211,"about_ca_system_score_gemma":0.000057458605,"threshold_uncertainty_score":0.17647691},"labels":[],"label_agreement":null},{"id":"W3013605673","doi":"10.1074/jbc.ra119.011193","title":"It takes two (Las1 HEPN endoribonuclease domains) to cut RNA correctly","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Nuclease; RNA; Biology; Endoribonuclease; Genetics; Cell biology; Computational biology; RNase P; Gene","score_opus":0.01651942423532247,"score_gpt":0.291811103127132,"score_spread":0.2752916788918095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013605673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98658115,0.0008319113,0.0071578063,0.0024015892,0.00018167296,0.00007195568,0.000020028672,0.000014143583,0.0027397498],"genre_scores_gemma":[0.9940066,0.00015324254,0.0020453865,0.0022161,0.0014249345,0.000002659248,0.000015501995,0.00001597811,0.0001196006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998901,0.000023577057,0.00039806464,0.0002577269,0.00015627663,0.0002633714],"domain_scores_gemma":[0.9990963,0.000024301264,0.0001411444,0.00016397354,0.000114364055,0.00045993392],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014671298,0.00019468257,0.00027325036,0.00001332974,0.00004022803,0.000025948317,0.00035180463,0.00016612963,0.00016125612],"category_scores_gemma":[0.00056254497,0.0001514341,0.00021865769,0.000102091704,0.0000626893,0.0000030449794,0.00010060109,0.00024295138,0.000016370539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023989084,0.00004191981,0.00046149318,0.000019796202,0.00004796085,0.00005746927,0.0000532408,0.00050066365,0.9885058,0.000002208255,0.00862113,0.0014484297],"study_design_scores_gemma":[0.00062987354,0.0004910332,0.00022267825,0.000019173205,0.000018511013,0.00015063827,0.00016492463,0.000054826953,0.9069837,0.0000141470855,0.09105035,0.00020018329],"about_ca_topic_score_codex":0.0000010812483,"about_ca_topic_score_gemma":7.784489e-7,"teacher_disagreement_score":0.08242922,"about_ca_system_score_codex":0.000016635773,"about_ca_system_score_gemma":0.000050280578,"threshold_uncertainty_score":0.61753035},"labels":[],"label_agreement":null},{"id":"W3013975168","doi":"10.1007/978-1-0716-0294-2_14","title":"Application of CRISPR/Cas9-Mediated Genome Editing in Leishmania","year":2020,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Biology; Cas9; Guide RNA; Gene; Leishmania; Genome; Computational biology; Trans-activating crRNA; Genetics","score_opus":0.013140606123639799,"score_gpt":0.3898788883675957,"score_spread":0.3767382822439559,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013975168","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10190239,0.0012680133,0.8961036,0.000211273,0.00006482828,0.00019679552,0.0000095525875,0.000009825768,0.0002336817],"genre_scores_gemma":[0.69873863,0.00006679593,0.30054006,0.00036544897,0.00010412942,0.00004140791,0.0001171089,0.000022787803,0.0000036128247],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986692,0.00027271552,0.00036907734,0.00039421036,0.000047262016,0.0002475302],"domain_scores_gemma":[0.99954927,0.00003642028,0.000081752696,0.00023651241,0.00003612126,0.00005994665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049144094,0.00014342858,0.00025428756,0.00008992956,0.00001009023,0.0000033224092,0.00021829394,0.00022277144,0.0000076126657],"category_scores_gemma":[0.00050878734,0.00015751955,0.00006333064,0.00027869735,0.000058816127,0.0000014059386,0.00013403664,0.000151005,0.0000026186501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021255191,0.00002066092,0.0062582823,0.000030401938,0.000012982365,0.000004641017,0.00007851079,0.0018220902,0.98634493,0.00015679505,0.000005943974,0.0052434877],"study_design_scores_gemma":[0.00053283386,0.00019076483,0.0042247246,0.0000060391003,0.0000072437037,0.000004431265,0.00007744731,0.0041975663,0.9828163,0.00022658713,0.007529956,0.00018614868],"about_ca_topic_score_codex":0.000035787954,"about_ca_topic_score_gemma":0.00001741923,"teacher_disagreement_score":0.59683627,"about_ca_system_score_codex":0.000011264175,"about_ca_system_score_gemma":0.00002381395,"threshold_uncertainty_score":0.6423461},"labels":[],"label_agreement":null},{"id":"W3014043586","doi":"10.1158/1078-0432.ccr-19-1627","title":"Generation of Genetically Engineered Mouse Lung Organoid Models for Squamous Cell Lung Cancers Allows for the Study of Combinatorial Immunotherapy","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"CRISPR; Cancer research; Organoid; Biology; Immunotherapy; Immune checkpoint; Genome editing; Cancer; Immunology; Immune system; Gene; Cell biology; Genetics","score_opus":0.1164828579181202,"score_gpt":0.46028509772617604,"score_spread":0.34380223980805585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014043586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88622934,0.0048194244,0.10596088,0.00024010333,0.00038291977,0.0022484441,0.000096811,0.0000068050254,0.000015251028],"genre_scores_gemma":[0.9965692,0.0009779633,0.0007592993,0.00006554805,0.0009466059,0.000538545,0.000030407356,0.00004556302,0.00006687237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983776,0.00011364951,0.00055300514,0.0003720277,0.00029360078,0.00029007325],"domain_scores_gemma":[0.998557,0.00034996428,0.00008128439,0.0003666755,0.0005420606,0.00010303157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091125414,0.00012822771,0.00027605376,0.000027747747,0.00008523954,0.000015396912,0.00040493012,0.00015069009,0.000014039784],"category_scores_gemma":[0.0003345883,0.00010541363,0.00015931763,0.00013535464,0.000099349156,0.000003291746,0.0000966649,0.00018575507,1.3728742e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014168876,0.00026529323,0.00044313492,0.00019178452,0.00017314432,2.0955854e-7,0.00047980298,0.14821738,0.8425345,0.000060918017,0.004671447,0.0015455252],"study_design_scores_gemma":[0.006598375,0.003775276,0.00015942837,0.000006504111,0.00007077078,1.09785994e-7,0.0003220973,0.3564292,0.63010114,0.000029696554,0.0023276855,0.00017971963],"about_ca_topic_score_codex":0.00012682872,"about_ca_topic_score_gemma":0.000064304266,"teacher_disagreement_score":0.21243332,"about_ca_system_score_codex":0.00003321804,"about_ca_system_score_gemma":0.0003445339,"threshold_uncertainty_score":0.42986432},"labels":[],"label_agreement":null},{"id":"W3014605631","doi":"10.1038/s41467-020-15449-9","title":"The translational landscape of ground state pluripotency","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"KWF Kankerbestrijding; Oncode Institute; Queen's University; Queen's University Belfast; European Commission","keywords":"Messenger RNA; Translational regulation; Biology; Proteome; Gene expression; Embryonic stem cell; Cell biology; Regulation of gene expression; Translation (biology); Translational efficiency; Gene; Post-transcriptional regulation; Ribosome profiling; Protein biosynthesis; Ribosome; Genetics; RNA","score_opus":0.010832872838840551,"score_gpt":0.29931708462379325,"score_spread":0.2884842117849527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014605631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.52785116,0.30718583,0.048866287,0.092407465,0.0005213599,0.00096580654,0.0003524459,0.000098501936,0.021751126],"genre_scores_gemma":[0.99607533,0.0016817631,0.0018593196,0.00017733431,0.000042279997,0.000006174474,0.000098288234,0.0000063145217,0.000053202337],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996834,0.000023337134,0.00010274237,0.00006887189,0.00006008066,0.00006161458],"domain_scores_gemma":[0.9993931,0.000034665838,0.000026989057,0.0004418368,0.000074471194,0.00002890905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058599977,0.000045567846,0.00004161204,0.0000068387562,0.000094071926,0.000007822753,0.00041087432,0.00006360353,0.000003392902],"category_scores_gemma":[0.000068339854,0.000035781974,0.000035744353,0.000090834525,0.000055312146,0.0000012434555,0.0000765432,0.00016536048,0.0000015121743],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017493535,0.00016311825,0.013200967,0.00006256974,0.00038715976,6.9129493e-7,0.0021365967,0.0058153374,0.8939788,0.019042354,0.02909052,0.035946965],"study_design_scores_gemma":[0.0005096981,0.00011542036,0.04090365,0.000007983866,0.000028563441,0.0000046062364,0.00016645681,0.0049210177,0.0429783,0.00039724816,0.9097727,0.00019436855],"about_ca_topic_score_codex":0.000001944123,"about_ca_topic_score_gemma":0.000064741,"teacher_disagreement_score":0.8806822,"about_ca_system_score_codex":9.4260133e-7,"about_ca_system_score_gemma":0.000029030354,"threshold_uncertainty_score":0.14591466},"labels":[],"label_agreement":null},{"id":"W3016153681","doi":"10.1146/annurev-genom-111919-082433","title":"Cultivating DNA Sequencing Technology After the Human Genome Project","year":2020,"lang":"en","type":"review","venue":"Annual Review of Genomics and Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Human Genome Research Institute","keywords":"DNA sequencing; Human genome; Genome; Sanger sequencing; Personal genomics; Computational biology; Biology; Data science; Computer science; DNA; Genetics; Gene","score_opus":0.020280937810012993,"score_gpt":0.35054329435584997,"score_spread":0.33026235654583697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016153681","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015265449,0.99665403,0.00009786695,0.00003824167,0.000053823227,0.0011719244,0.00019155831,0.000013980618,0.00025203533],"genre_scores_gemma":[0.0006916564,0.99749523,0.00062300806,0.00018204273,0.00042443044,0.00015096409,0.00020440185,0.000102507576,0.00012574885],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978019,0.00009050098,0.0009835088,0.00061987643,0.00014933004,0.00035490567],"domain_scores_gemma":[0.99857825,0.000016493163,0.00046805863,0.0007159906,0.00014020977,0.000080987644],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033071157,0.00053328427,0.0013264064,0.00011133173,0.00017493597,0.000032060958,0.0005972024,0.00033762248,0.000011208983],"category_scores_gemma":[0.00005576706,0.00040311774,0.0004007992,0.0002340637,0.00021463851,0.000002476063,0.00066220283,0.00035896062,0.000004033513],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000067387873,0.000050369155,0.000024108936,0.16513263,0.0009460553,0.000029417843,0.00063990726,0.0000076005563,0.022341711,0.0003882662,0.0008758284,0.8095574],"study_design_scores_gemma":[0.00008184056,0.00023130227,0.000008600381,0.009944754,0.0005699048,0.00007749603,0.00010309049,9.943205e-7,0.00027510844,0.000025392997,0.9882455,0.00043601988],"about_ca_topic_score_codex":0.0000060395914,"about_ca_topic_score_gemma":0.000008611086,"teacher_disagreement_score":0.98736966,"about_ca_system_score_codex":0.000046119003,"about_ca_system_score_gemma":0.00025936813,"threshold_uncertainty_score":0.99984205},"labels":[],"label_agreement":null},{"id":"W3016449795","doi":"10.1534/g3.120.401299","title":"A Method for Rapid Selection of Randomly Induced Mutations in a Gene of Interest Using CRISPR/Cas9 Mediated Activation of Gene Expression","year":2020,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institutes of Health","keywords":"CRISPR; Allele; Phenotype; Biology; Gene; Genetics; Cas9; Mutant; Point mutation; Mutation; Loss function; Function (biology)","score_opus":0.05359732269554448,"score_gpt":0.351122187496456,"score_spread":0.29752486480091156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016449795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.61700374,0.011994283,0.3704372,0.00002743801,0.000048689046,0.00042208415,0.000055930916,0.0000055030564,0.000005127247],"genre_scores_gemma":[0.8563308,0.0023449908,0.1409447,0.000027715723,0.00011282549,0.000032986,0.00016501058,0.000037650396,0.0000032952644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998544,0.00009844207,0.00067733985,0.00033928757,0.0001280785,0.00021287825],"domain_scores_gemma":[0.9990055,0.00006748233,0.0003394577,0.00021669657,0.00029183138,0.00007906473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023043198,0.00020141061,0.00039540697,0.00017271482,0.000030178762,0.0000055470973,0.00017617994,0.0002026452,0.000010231673],"category_scores_gemma":[0.00006285205,0.0002167774,0.00014525041,0.00035756503,0.000038135157,0.00000565833,0.000074546944,0.00007069256,1.8355095e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036123005,0.00006147556,0.0010778123,0.00018910803,0.000076606295,2.1437147e-7,0.00051769166,0.0391426,0.92307335,0.0000022969957,0.000008937689,0.03548865],"study_design_scores_gemma":[0.0019801727,0.00052317174,0.00040743395,0.00003095769,0.000064335036,0.00000392784,0.00023643753,0.026157908,0.96984285,0.000017129962,0.000552636,0.00018304023],"about_ca_topic_score_codex":0.000021422877,"about_ca_topic_score_gemma":0.000016522607,"teacher_disagreement_score":0.2393271,"about_ca_system_score_codex":0.00001822984,"about_ca_system_score_gemma":0.00013490346,"threshold_uncertainty_score":0.88399255},"labels":[],"label_agreement":null},{"id":"W3016457421","doi":"10.1038/s41467-020-15796-7","title":"Perturbing proteomes at single residue resolution using base editing","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Université Laval","keywords":"CRISPR; Genome editing; Computational biology; Proteome; Guide RNA; Gene; Genome; Context (archaeology); Biology; Cas9; Genetics; RNA editing; RNA","score_opus":0.031288468911497724,"score_gpt":0.3205597658883621,"score_spread":0.2892712969768644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016457421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88970256,0.048821695,0.036313348,0.01781988,0.00041020237,0.0008945547,0.00007996056,0.00019352176,0.0057642497],"genre_scores_gemma":[0.9731371,0.00012286495,0.025591055,0.0005635038,0.0003510562,0.000013186916,0.00014895668,0.00002112116,0.000051179253],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999385,0.000054341097,0.0001378573,0.00019025624,0.00008518305,0.00014739064],"domain_scores_gemma":[0.99910045,0.000021506588,0.000050525596,0.00067847,0.0000749822,0.000074086725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008989268,0.00009745029,0.0000769787,0.000022608387,0.00025934918,0.000020450505,0.00036909725,0.00019540812,0.000012588396],"category_scores_gemma":[0.0003909815,0.00010454218,0.000052512252,0.00011460393,0.000046143905,0.00000389335,0.0004658332,0.00029788844,0.0000057729812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008954402,0.00001856119,0.0006948288,0.000013199226,0.000014693833,5.453379e-7,0.00013576206,0.0013068538,0.9946498,0.00007573717,0.0027840212,0.0002969896],"study_design_scores_gemma":[0.00037590202,0.000112781716,0.0012126653,0.00004916906,0.00003894245,0.000021067897,0.00024373484,0.031809278,0.8094901,0.000015019221,0.1563157,0.00031567528],"about_ca_topic_score_codex":0.00000677635,"about_ca_topic_score_gemma":0.000059726073,"teacher_disagreement_score":0.18515979,"about_ca_system_score_codex":0.000032566306,"about_ca_system_score_gemma":0.000026591028,"threshold_uncertainty_score":0.42631063},"labels":[],"label_agreement":null},{"id":"W3017176450","doi":"10.1096/fasebj.2020.34.s1.02133","title":"Dynamics of allosteric activation in PLC‐γ isozymes","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Isozyme; Second messenger system; Cell biology; Diacylglycerol kinase; Phosphatidylinositol; Biochemistry; Biology; SH2 domain; Phosphorylation; Phospholipase C; HAMP domain; Chemistry; Tyrosine phosphorylation; Protein kinase C; Signal transduction; Binding domain; Binding site; Enzyme","score_opus":0.009783295338245807,"score_gpt":0.2630829576298417,"score_spread":0.2532996622915959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017176450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9729611,0.00017309553,0.02528689,0.0013146709,0.0000391689,0.000032948145,0.0000020156792,0.000001568252,0.00018851733],"genre_scores_gemma":[0.9993441,0.000088881665,0.00023731694,0.00016403467,0.00012324762,6.3325496e-7,0.000007299384,0.000005855854,0.000028648881],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968946,0.000018972694,0.00011093101,0.00005183063,0.000055554745,0.00007325246],"domain_scores_gemma":[0.99984145,0.0000054352045,0.000041761574,0.000063885695,0.000017608905,0.000029867873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007618388,0.000045032026,0.000053682932,0.000014090802,0.000018081444,0.0000073514057,0.00010269437,0.000028679206,0.000012424277],"category_scores_gemma":[0.00003320677,0.00003344757,0.000032994467,0.000054109743,0.000014860241,0.000001629655,0.000031010848,0.000084592706,9.587487e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034649995,0.000007149218,0.0013072672,0.000006250998,0.00001170914,8.068456e-7,0.00015033668,0.0031096067,0.9933476,0.000021434149,0.000111548754,0.0018916585],"study_design_scores_gemma":[0.0002877678,0.000135843,0.003748473,0.00001159721,0.000005823122,0.000019776515,0.00031110938,0.004080029,0.9909901,0.000055644494,0.00029557777,0.00005823255],"about_ca_topic_score_codex":0.0000027715962,"about_ca_topic_score_gemma":0.000006761858,"teacher_disagreement_score":0.026382957,"about_ca_system_score_codex":0.0000063459365,"about_ca_system_score_gemma":0.000018643666,"threshold_uncertainty_score":0.13639523},"labels":[],"label_agreement":null},{"id":"W3017782040","doi":"10.1021/acs.biochem.0c00275","title":"Allosteric Control of Enzyme Activity: From Ancient Origins to Recent Gene-Editing Technologies","year":2020,"lang":"en","type":"letter","venue":"Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Haven; Citation; Phone; Library science; Allosteric regulation; Art history; World Wide Web; Computer science; Chemistry; History; Philosophy; Biochemistry; Mathematics; Enzyme; Combinatorics","score_opus":0.010342415311290801,"score_gpt":0.2587402060114906,"score_spread":0.24839779070019982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017782040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5598876,0.012736884,0.04842657,0.3709067,0.0018228202,0.0011619168,0.0041167843,0.00039756479,0.00054316793],"genre_scores_gemma":[0.90982395,0.00048991555,0.002437961,0.08041791,0.004869951,0.00010686535,0.0014877853,0.00011871588,0.00024693212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981364,0.00002013271,0.0003205804,0.00081416266,0.00028092152,0.00042779284],"domain_scores_gemma":[0.99882144,0.00002338618,0.00019044717,0.00076628936,0.000109411376,0.00008905809],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000509224,0.00042407407,0.0004508343,0.000048750888,0.000038502658,0.000027264941,0.0005392591,0.00088643696,0.000023935158],"category_scores_gemma":[0.00023243453,0.00045137326,0.00017731989,0.00015482622,0.00007721676,0.000001640215,0.0003159894,0.0005472506,0.000011402909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027316682,0.000014520228,0.000031067662,0.000112966874,0.00011272747,0.000037441696,0.000010101541,0.000032295997,0.75473124,8.310122e-8,0.24278098,0.0021092396],"study_design_scores_gemma":[0.00020352108,0.00006505124,0.0000099394365,0.000040244602,0.000040797047,0.000006170467,0.000020953361,0.000031487256,0.59097254,0.0000020139446,0.40835068,0.0002566162],"about_ca_topic_score_codex":0.000019957344,"about_ca_topic_score_gemma":0.0000015485709,"teacher_disagreement_score":0.3499364,"about_ca_system_score_codex":0.00007316617,"about_ca_system_score_gemma":0.00013543955,"threshold_uncertainty_score":0.9997938},"labels":[],"label_agreement":null},{"id":"W3018428740","doi":"10.1016/j.molcel.2020.04.007","title":"A Family of Argonaute-Interacting Proteins Gates Nuclear RNAi","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Cancer Research UK; Human Frontier Science Program; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Argonaute; RNA interference; Biology; Piwi-interacting RNA; RasiRNA; Genetics; Epigenetics; Gene silencing; Germline; Cell biology; Caenorhabditis elegans; Gene; RNA","score_opus":0.006495592036190433,"score_gpt":0.2432312902615753,"score_spread":0.23673569822538487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3018428740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9577861,0.0011880238,0.033936925,0.0002698451,0.000066971195,0.00019368035,0.000007467369,0.00002327143,0.006527722],"genre_scores_gemma":[0.9940489,0.000038130114,0.005251192,0.00046714165,0.00007154149,0.000005826767,0.00001804333,0.000037656115,0.00006158722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992825,0.000020636724,0.0001727983,0.00024889107,0.000102328006,0.00017285882],"domain_scores_gemma":[0.9996063,0.000004026756,0.00005717428,0.00020104721,0.00004006679,0.0000913691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004333767,0.00012771989,0.00013164298,0.000018917193,0.000022549779,0.000013084144,0.000164016,0.000073132556,0.000018976158],"category_scores_gemma":[0.00004978565,0.00013620898,0.00011036799,0.000072322044,0.000022048109,0.000001760917,0.0001127119,0.00008691145,0.000018578981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027988805,0.00002583886,0.00006779732,0.000068387446,0.000022972834,0.000013290367,0.00011313463,0.001531891,0.99718165,0.000037288955,0.0003953532,0.0005143915],"study_design_scores_gemma":[0.0002892983,0.00021986467,0.00010767333,0.000014401411,0.000013961892,0.00000261468,0.00010798945,0.0013489798,0.97147596,0.000008808574,0.026261471,0.00014898466],"about_ca_topic_score_codex":0.000009678382,"about_ca_topic_score_gemma":6.3016495e-7,"teacher_disagreement_score":0.036262788,"about_ca_system_score_codex":0.0000033441465,"about_ca_system_score_gemma":0.00002322049,"threshold_uncertainty_score":0.55544406},"labels":[],"label_agreement":null},{"id":"W3019816543","doi":"10.1101/2020.04.21.053090","title":"FORCAST: a fully integrated and open source pipeline to design Cas-mediated mutagenesis experiments","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; SickKids Foundation; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"","keywords":"Computer science; Software portability; Pipeline (software); Source code; Software; Open source; Software engineering; Usability; Computational biology; Operating system; Biology","score_opus":0.021680421469684144,"score_gpt":0.2784075574915421,"score_spread":0.256727136021858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019816543","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47942528,0.0021465088,0.5157926,0.0003446449,0.00040924174,0.0014999341,0.00023680658,0.0001396819,0.000005257998],"genre_scores_gemma":[0.9675654,0.00026875013,0.030400632,0.0007858998,0.0003615443,0.00038950253,0.000006158345,0.00019560372,0.000026468473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738795,0.0001167976,0.00047145344,0.0012969421,0.00021155266,0.00051532185],"domain_scores_gemma":[0.99804544,0.000024179328,0.00016530111,0.00093264104,0.00027436676,0.0005580404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003573837,0.00063311215,0.0005675886,0.00013452172,0.000111957655,0.00029207038,0.00083183625,0.0005053294,0.000023455488],"category_scores_gemma":[0.0003822982,0.0006890235,0.000097497374,0.00031670494,0.00005633102,0.000008430156,0.0020517306,0.00033068514,0.000031631225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015480528,0.000055352324,0.00033359602,0.00010068595,0.0001574489,0.00003209646,0.000032204145,0.0012307629,0.9955583,0.000003374135,0.0023218982,0.000019462363],"study_design_scores_gemma":[0.0007246087,0.00022226293,0.0020391913,0.00011739802,0.00008214543,9.912967e-8,0.000012911002,0.0021861128,0.96695024,3.7105244e-7,0.026822232,0.0008424224],"about_ca_topic_score_codex":0.00010166798,"about_ca_topic_score_gemma":0.0000057239968,"teacher_disagreement_score":0.48814014,"about_ca_system_score_codex":0.00007350998,"about_ca_system_score_gemma":0.00037779752,"threshold_uncertainty_score":0.99955606},"labels":[],"label_agreement":null},{"id":"W3020430037","doi":"10.1016/j.chom.2020.04.001","title":"Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes","year":2020,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Lytic cycle; Biology; CRISPR; Cas9; Lysogenic cycle; Listeria; Prophage; Bacteriophage; Genome; Microbiology; Listeria monocytogenes; Genetics; Bacteria; Virus; Escherichia coli; Gene","score_opus":0.010966251157466637,"score_gpt":0.2611662163160983,"score_spread":0.2501999651586317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020430037","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5486096,0.04749121,0.029749932,0.35684758,0.0045691323,0.0068122707,0.0014279226,0.0003695325,0.004122831],"genre_scores_gemma":[0.1849073,0.0016871385,0.010115473,0.7306559,0.017738681,0.00052067236,0.010045204,0.0007601344,0.04356949],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99839133,0.000048408045,0.00028168998,0.0007321598,0.00012528223,0.0004211462],"domain_scores_gemma":[0.9991797,0.000008023921,0.000097421536,0.0005439113,0.00006382265,0.000107096654],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005530204,0.00042209902,0.00030001835,0.00008215337,0.00007352804,0.00008047099,0.0004156814,0.00057105167,0.00007117081],"category_scores_gemma":[0.000022985272,0.000454498,0.0001780118,0.00012907588,0.000029583114,0.0000023129178,0.00027743567,0.0005095041,0.00017365099],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000871877,0.0000068238464,0.000006170595,0.00014087126,0.000031287258,0.000038541257,0.00005762713,0.000010825091,0.624005,4.4533095e-8,0.3751232,0.000570868],"study_design_scores_gemma":[0.00011613379,0.00010032454,0.00001872698,0.000016075404,0.00003209059,0.000017783397,0.000009680151,0.0000018680822,0.48559016,6.645434e-7,0.5138126,0.00028391785],"about_ca_topic_score_codex":0.000023673867,"about_ca_topic_score_gemma":0.000010333393,"teacher_disagreement_score":0.37380832,"about_ca_system_score_codex":0.000036976355,"about_ca_system_score_gemma":0.00009791679,"threshold_uncertainty_score":0.99979067},"labels":[],"label_agreement":null},{"id":"W3020997026","doi":"10.1344/rbd2020.49.29384","title":"La protección de la diversidad en el patrimonio genético: implicaciones bioéticas y jurídicas en el uso de CRISPR-Cas9 como herramienta de edición genómica en humanos","year":2020,"lang":"es","type":"article","venue":"Revista de Bioética y Derecho","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Humanities; Philosophy; Political science","score_opus":0.008296304003293445,"score_gpt":0.3434210293723198,"score_spread":0.3351247253690263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020997026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8810269,0.014426427,0.09649763,0.004560939,0.00014431388,0.0015405683,0.00038153288,0.00022074714,0.0012009382],"genre_scores_gemma":[0.98105824,0.008301095,0.0075709773,0.0011258826,0.0014163131,0.00012555158,0.00012980597,0.00019638485,0.00007576142],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943486,0.0015820495,0.0008501421,0.0012616898,0.00041678586,0.0015407201],"domain_scores_gemma":[0.9968884,0.00058395136,0.00025423412,0.0010130331,0.00013468256,0.0011256835],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0014891835,0.00088510296,0.00084299274,0.00016164184,0.00032547282,0.00054787844,0.0011860359,0.001605278,0.00009634592],"category_scores_gemma":[0.0014908306,0.00094900787,0.0005658068,0.00038943856,0.0004104168,0.000021140757,0.0008656505,0.0011914412,0.000054970194],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003178327,0.00044350943,0.021786787,0.0017292179,0.00072837214,0.00036618108,0.0023788698,0.00016736,0.95285,0.0028488333,0.0047044503,0.011678626],"study_design_scores_gemma":[0.0032154769,0.0013693592,0.030183746,0.0007747499,0.0017230648,0.0011820118,0.00194532,0.0038860135,0.41620064,0.00035566563,0.536656,0.0025079204],"about_ca_topic_score_codex":0.00017158396,"about_ca_topic_score_gemma":0.0000046221285,"teacher_disagreement_score":0.5366493,"about_ca_system_score_codex":0.0004847944,"about_ca_system_score_gemma":0.0007730456,"threshold_uncertainty_score":0.99969083},"labels":[],"label_agreement":null},{"id":"W3021442850","doi":"10.1016/j.btre.2020.e00460","title":"How should we regulate products of new breeding techniques? Opinion of surveyed experts in plant biotechnology","year":2020,"lang":"en","type":"article","venue":"Biotechnology Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canada First Research Excellence Fund; Genome Canada","keywords":"Biotechnology; Product (mathematics); Genome editing; Agriculture; Agricultural biotechnology; Process (computing); Emerging technologies; Business; Genome; Biology; Computer science; Genetics; Gene","score_opus":0.03330935480910506,"score_gpt":0.28875088875047356,"score_spread":0.2554415339413685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021442850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.950539,0.0065421825,0.011637302,0.029847044,0.0004150766,0.0007033039,0.000019281428,0.00023750463,0.000059330516],"genre_scores_gemma":[0.9929078,0.0017366292,0.005034359,0.00003976099,0.00011552365,0.000013921794,0.00005172557,0.00003292971,0.00006730648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983648,0.000023578557,0.00054793456,0.00062941987,0.00013223267,0.00030200285],"domain_scores_gemma":[0.99886745,0.000007292721,0.0003337717,0.00066847354,0.000058332724,0.000064685955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023358491,0.00023113555,0.0004348985,0.00024048085,0.000016837206,0.0000058828355,0.0002532458,0.0010557857,0.0000024480798],"category_scores_gemma":[0.00051954464,0.00023006016,0.00007624955,0.00047833723,0.00024666177,0.0000056237054,0.00027924078,0.00020744943,1.7841182e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048738722,0.000034753055,0.0023287989,0.00010359589,0.000033079046,0.00004642812,0.000057743022,0.000021178812,0.9867242,0.00013064267,0.0017522641,0.008718604],"study_design_scores_gemma":[0.00019927594,0.00048668517,0.0004702215,0.000071115595,0.000007653924,0.00026819,0.00012246422,0.000034840472,0.95698315,0.00006310314,0.04108916,0.00020415592],"about_ca_topic_score_codex":0.00006767529,"about_ca_topic_score_gemma":0.000030798492,"teacher_disagreement_score":0.04236887,"about_ca_system_score_codex":0.000013383866,"about_ca_system_score_gemma":0.000100472316,"threshold_uncertainty_score":0.9381581},"labels":[],"label_agreement":null},{"id":"W3021645731","doi":"10.21769/bioprotoc.3615","title":"Rapid Generation of Human Neuronal Cell Models Enabling Inducible Expression of Proteins-of-interest for Functional Studies","year":2020,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Biology; CRISPR; Computational biology; Gene; Genetics","score_opus":0.2203415714327725,"score_gpt":0.3799091931003061,"score_spread":0.15956762166753358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021645731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6488466,0.00017198005,0.09764293,0.00006786137,0.00009252016,0.25296423,0.000061187755,0.00001594868,0.0001367377],"genre_scores_gemma":[0.82648146,0.0000026425644,0.0024009605,0.000018140403,0.00025334652,0.1707701,0.00003383462,0.000014987746,0.000024554925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992827,0.000019856614,0.00030536082,0.00021492584,0.00008362346,0.00009353831],"domain_scores_gemma":[0.9995082,0.0000069712914,0.00014569772,0.00014482444,0.00015990066,0.000034394216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088902416,0.000103377104,0.00015372032,0.00003139167,0.00003368226,0.0000036099907,0.000085489955,0.00007473849,0.000010150017],"category_scores_gemma":[0.00003739229,0.00009292942,0.000083301085,0.000048075828,0.000036431888,0.0000047141975,0.00007798668,0.000038415867,1.3939973e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017439299,0.000061145154,0.00004545673,0.00063191506,0.000016930022,7.11446e-8,0.00007079072,0.0037623527,0.99400675,0.000045838267,0.0007660826,0.000418267],"study_design_scores_gemma":[0.0010460463,0.0009778225,0.00004282087,0.000038714203,0.00000789864,2.2449622e-7,0.000060602444,0.0016582893,0.99364954,0.000032506392,0.0024015561,0.00008395016],"about_ca_topic_score_codex":0.0000021433596,"about_ca_topic_score_gemma":0.0000015944764,"teacher_disagreement_score":0.17763482,"about_ca_system_score_codex":0.0000035624728,"about_ca_system_score_gemma":0.000036853522,"threshold_uncertainty_score":0.37895516},"labels":[],"label_agreement":null},{"id":"W3023817783","doi":"10.1101/2020.05.07.083444","title":"Automated design of CRISPR prime editors for thousands of human pathogenic variants","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Advanced Research Projects Agency; National Institutes of Health; York University; Sidney Kimmel Foundation; Canadian Institutes of Health Research; Melanoma Research Alliance","keywords":"CRISPR; Genome editing; Computational biology; Human genome; Computer science; Human disease; Genome; Gene; dbSNP; Cas9; Prime (order theory); Genetics; Biology; Genotype; Single-nucleotide polymorphism; Mathematics","score_opus":0.015396559371364606,"score_gpt":0.2746169704372924,"score_spread":0.2592204110659278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023817783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5108696,0.002115381,0.48138803,0.000062888495,0.0025368382,0.0017869953,0.00092183216,0.00031355227,0.000004848166],"genre_scores_gemma":[0.9808387,0.00012371968,0.017278796,0.000023499753,0.0014508611,0.00014111392,0.000004365891,0.00013664382,0.0000022969732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978906,0.00008601998,0.0006641564,0.0007569316,0.00022802755,0.0003742815],"domain_scores_gemma":[0.9979583,0.000028737351,0.00044962586,0.00094381673,0.00044951082,0.0001700223],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042059587,0.0004422455,0.00062102417,0.00012362449,0.000060380757,0.000026886011,0.00053243106,0.0006323683,0.0000072629755],"category_scores_gemma":[0.00021312432,0.0004974831,0.00025437563,0.00019133589,0.00010365631,0.0000042428037,0.00037842724,0.00022306075,0.0000016413044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066436565,0.00009058758,0.00033130546,0.0006239103,0.00027385567,0.0000035485991,0.000007913928,0.0015922254,0.9953553,0.000033364286,0.0016203312,0.0000011936346],"study_design_scores_gemma":[0.0006272899,0.00037405652,0.008913468,0.0001553786,0.0001817564,1.4627464e-8,0.000001958011,0.0035432228,0.9851207,0.000002163431,0.00060884934,0.00047111942],"about_ca_topic_score_codex":0.000009999271,"about_ca_topic_score_gemma":2.9716645e-7,"teacher_disagreement_score":0.46996906,"about_ca_system_score_codex":0.000029914157,"about_ca_system_score_gemma":0.00042049424,"threshold_uncertainty_score":0.9997477},"labels":[],"label_agreement":null},{"id":"W3024596941","doi":"10.1016/j.cll.2020.02.008","title":"Therapeutic Gene Editing with CRISPR","year":2020,"lang":"en","type":"review","venue":"Clinics in Laboratory Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Gene; Biology; Genetics","score_opus":0.032987462782870874,"score_gpt":0.40550393887773645,"score_spread":0.3725164760948656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3024596941","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000029107794,0.9962671,0.002135526,0.000091283255,0.0007528559,0.00037964483,0.000041935244,0.000024030622,0.0002785404],"genre_scores_gemma":[0.0001919231,0.99513173,0.00046998254,0.00046427915,0.0032674384,0.00006423646,0.0002549641,0.00010985508,0.000045577297],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980137,0.00012938312,0.0007322102,0.0006192967,0.00020161794,0.0003038098],"domain_scores_gemma":[0.99885,0.00008660794,0.00024617775,0.0005553709,0.000104927996,0.00015693509],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004975764,0.00044093851,0.001220791,0.00011501307,0.000032827138,0.000009105647,0.00034400207,0.0004268435,0.000026208212],"category_scores_gemma":[0.0003114975,0.000325387,0.00010889404,0.0005190336,0.00014660948,0.0000019216495,0.00009124449,0.00057702087,0.000014266079],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036846508,0.0000652456,0.00011751418,0.007094605,0.00040698462,0.00021494512,0.00012645741,0.000041358915,0.00034640337,0.00005764035,0.0033714778,0.9881205],"study_design_scores_gemma":[0.0005034705,0.00044850173,0.0000062523277,0.0030180973,0.00030189662,0.000021355714,0.000057472087,0.00001104542,0.00012740196,0.00000524165,0.99517465,0.00032460358],"about_ca_topic_score_codex":0.0000018041152,"about_ca_topic_score_gemma":0.000010572194,"teacher_disagreement_score":0.99180317,"about_ca_system_score_codex":0.000029540062,"about_ca_system_score_gemma":0.00039840717,"threshold_uncertainty_score":0.99991983},"labels":[],"label_agreement":null},{"id":"W3025058453","doi":"10.1016/j.tips.2020.04.009","title":"Rewired Cas9s with Minimal Sequence Constraints","year":2020,"lang":"en","type":"letter","venue":"Trends in Pharmacological Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Computational biology; Cas9; Biology; Genome engineering; Gene; Genome; Genetics","score_opus":0.06377986607646954,"score_gpt":0.38742174409588365,"score_spread":0.32364187801941413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025058453","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.22589894,0.0020551097,0.0008136689,0.7279094,0.0013287792,0.0006382591,0.00030605888,0.00017357836,0.040876213],"genre_scores_gemma":[0.7896942,0.00013730183,0.0020807476,0.20567495,0.0014314242,0.000050716815,0.00016085543,0.000018965262,0.0007508449],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99815404,0.000077420955,0.00022407112,0.00075245474,0.00029300828,0.000499015],"domain_scores_gemma":[0.9996633,0.000035954843,0.00007359903,0.00011227328,0.000021412709,0.00009348509],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000147865,0.0002775157,0.00025778232,0.00009467126,0.000080889775,0.0000429775,0.000558281,0.0003146179,0.0004530616],"category_scores_gemma":[0.000030686537,0.00019716605,0.00007393534,0.00043840782,0.0010600326,0.0000035630148,0.00013367346,0.0005986087,0.00000927591],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072686686,0.000056410263,0.0007333522,0.000030793046,0.000062787214,0.0018718767,0.000051285453,0.00050418114,0.16513208,0.0000071176682,0.8128669,0.018610494],"study_design_scores_gemma":[0.0018947384,0.0029086561,0.0010906179,0.00006883659,0.00012413053,0.00033050773,0.00007847515,0.0009993262,0.09687259,0.00006547567,0.89412063,0.0014459823],"about_ca_topic_score_codex":0.00000909981,"about_ca_topic_score_gemma":0.000010688136,"teacher_disagreement_score":0.56379527,"about_ca_system_score_codex":0.000020678908,"about_ca_system_score_gemma":0.000090534006,"threshold_uncertainty_score":0.8040198},"labels":[],"label_agreement":null},{"id":"W3025263087","doi":"10.1021/acschembio.0c00253","title":"CRISPR-Based Screen Links an Inhibitor of Nonsense-Mediated Decay to eIF4A3 Target Engagement","year":2020,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Nonsense-mediated decay; CRISPR; Biology; RNA splicing; Exon; Genetics; Stop codon; Intron; RNA; Cell biology; Gene","score_opus":0.016638771796756484,"score_gpt":0.31678578751252384,"score_spread":0.30014701571576735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025263087","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747913,0.00025025752,0.022907691,0.0014265454,0.00008940377,0.00021564835,0.000121247045,0.00003482336,0.00016310757],"genre_scores_gemma":[0.9877431,0.00001773706,0.008340525,0.0026832954,0.00037753323,0.00001879638,0.00078586873,0.000026014777,0.000007144177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879485,0.00006450359,0.0003027326,0.0004532106,0.00007886593,0.00030581723],"domain_scores_gemma":[0.9992231,0.000046474433,0.000052429412,0.00030188827,0.00008540393,0.0002907079],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349571,0.00019105025,0.0002546546,0.000035562356,0.000024233803,0.0000057812913,0.00026450446,0.00040260376,0.000040230098],"category_scores_gemma":[0.0003269958,0.00018276808,0.00007963253,0.00013367983,0.00007868652,0.0000016436103,0.00016909759,0.00021871965,0.00002133118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001669472,0.00006026038,0.000997867,0.00002006568,0.00003309656,0.0000020965279,0.00005888116,0.00022735329,0.99573624,0.00001809075,0.0019382562,0.0007408684],"study_design_scores_gemma":[0.00057970104,0.0006899156,0.00014439423,0.0000061255205,0.000013797054,0.0000012664303,0.000028716962,0.0002886961,0.96614665,0.000007891281,0.031882823,0.00021003853],"about_ca_topic_score_codex":0.00001172478,"about_ca_topic_score_gemma":0.0000029979312,"teacher_disagreement_score":0.029944567,"about_ca_system_score_codex":0.000008954242,"about_ca_system_score_gemma":0.000055426783,"threshold_uncertainty_score":0.7453066},"labels":[],"label_agreement":null},{"id":"W3025812418","doi":"10.1016/j.ymthe.2020.05.007","title":"Immunity to Cas9 as an Obstacle to Persistent Genome Editing","year":2020,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health","keywords":"CRISPR; Population; Scopus; Cas9; Biology; Genome editing; Genetics; Medicine; Gene","score_opus":0.013598591596097552,"score_gpt":0.28605257332443595,"score_spread":0.2724539817283384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025812418","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6762192,0.0047365036,0.02248037,0.29268822,0.00096149306,0.0015034243,0.0001633308,0.00012595142,0.001121486],"genre_scores_gemma":[0.1508455,0.00012567181,0.002237844,0.8399173,0.0042319954,0.00012133784,0.0014162561,0.00023188927,0.0008722306],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980599,0.000106458734,0.0002519257,0.0007457255,0.00030757068,0.00052837795],"domain_scores_gemma":[0.9986417,0.0000062060913,0.00005275206,0.00091154623,0.000100308236,0.000287453],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009834176,0.00043796646,0.000316001,0.00009264779,0.00010800189,0.000088590496,0.00062837364,0.0004153509,0.00006771462],"category_scores_gemma":[0.00004931694,0.00048048087,0.00031641303,0.00015746968,0.000023063249,0.0000022447423,0.00020493126,0.0005641982,0.00013218536],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004721694,0.000024010473,0.00000480641,0.000027154845,0.00020644547,0.0003074435,0.00043979252,0.0013238585,0.93966866,0.0000015142105,0.055538196,0.0024108994],"study_design_scores_gemma":[0.00023881701,0.0010532592,0.000030873558,0.00001419658,0.000021406604,0.000038463626,0.00009050882,0.000016157966,0.19867161,0.0000103622215,0.7993153,0.0004990512],"about_ca_topic_score_codex":0.00007375715,"about_ca_topic_score_gemma":0.000005893054,"teacher_disagreement_score":0.7437771,"about_ca_system_score_codex":0.000041246934,"about_ca_system_score_gemma":0.0000672172,"threshold_uncertainty_score":0.9997647},"labels":[],"label_agreement":null},{"id":"W3026606344","doi":"10.1002/advs.201903562","title":"CRISPR‐Net: A Recurrent Convolutional Network Quantifies CRISPR Off‐Target Activities with Mismatches and Indels","year":2020,"lang":"en","type":"article","venue":"Advanced Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Health and Medical Research Fund; City University of Hong Kong","keywords":"CRISPR; Computer science; Indel; Computational biology; In silico; Guide RNA; Code (set theory); Tree (set theory); Artificial intelligence; Data mining; Gene; Cas9; Genetics; Biology; Set (abstract data type)","score_opus":0.010277524491662852,"score_gpt":0.2838149168541789,"score_spread":0.27353739236251606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026606344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8989009,0.005934321,0.09397749,0.0005371905,0.00017648329,0.00015952947,0.000014645216,0.000029508154,0.00026990182],"genre_scores_gemma":[0.9865679,0.00032576855,0.012569423,0.00031181236,0.00013804235,0.000014894099,0.000009209754,0.000011015901,0.000051893217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989298,0.000012680381,0.00011820417,0.0004287325,0.00019655567,0.00031404715],"domain_scores_gemma":[0.9995701,0.000021682361,0.00004410099,0.00015695217,0.000060606057,0.00014659246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011765865,0.00014186262,0.00012404032,0.000022238766,0.00018198052,0.000042500462,0.00017595658,0.000039313356,0.000007202568],"category_scores_gemma":[0.00008080754,0.00012450245,0.000023670584,0.00020255319,0.00041411148,0.00002120888,0.000116679046,0.0000849275,0.0000015326293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028446488,0.00003445074,0.006461822,0.00008133673,0.000033924913,0.0000057736797,0.0008227037,0.06956607,0.91298455,0.00073617813,0.0011419933,0.007846755],"study_design_scores_gemma":[0.0010892544,0.0012749117,0.013826354,0.00009759508,0.000023405337,0.000043761964,0.0014753431,0.011490034,0.9285341,0.00038401617,0.04100625,0.00075496506],"about_ca_topic_score_codex":0.0000023679731,"about_ca_topic_score_gemma":0.000015315365,"teacher_disagreement_score":0.087667,"about_ca_system_score_codex":0.0000085159645,"about_ca_system_score_gemma":0.00012471771,"threshold_uncertainty_score":0.5077062},"labels":[],"label_agreement":null},{"id":"W3027038845","doi":"10.3389/fmolb.2020.00098","title":"Bio-Layer Interferometry Analysis of the Target Binding Activity of CRISPR-Cas Effector Complexes","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Biosciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"International Max Planck Research School for Advanced Methods in Process and Systems Engineering; University of Toronto; Deutsche Forschungsgemeinschaft; International Max Planck Research School for Environmental, Cellular and Molecular Microbiology; Justus Liebig Universität Gießen","keywords":"CRISPR; Effector; Biotinylation; Microscale thermophoresis; Nucleic acid; Computational biology; Chemistry; CRISPR interference; Biology; Biochemistry; Gene; Genome editing","score_opus":0.009712974658078773,"score_gpt":0.28278689430510107,"score_spread":0.27307391964702227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3027038845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7484107,0.00057261466,0.25050703,0.00011074188,0.00021965528,0.00009832178,0.00003484358,0.000003345028,0.000042758977],"genre_scores_gemma":[0.99266666,0.000029249488,0.007193757,0.00006779771,0.000015150757,0.0000037383631,0.000008829233,0.0000075979,0.000007203398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989851,0.00008371723,0.00021028458,0.00031794186,0.00021595781,0.00018701228],"domain_scores_gemma":[0.99953085,0.000010620089,0.000111513276,0.00025785208,0.000032470725,0.000056667093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019310473,0.00012934128,0.00028938652,0.00022072191,0.000033775766,0.000012031121,0.00047367378,0.00007727807,0.0000061528735],"category_scores_gemma":[0.0001697537,0.000099849945,0.00021988578,0.001627909,0.00024125101,0.0000045776337,0.00018696747,0.000077953104,2.6515127e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019479907,0.000023923196,0.12958735,0.000028300965,0.00014617441,7.861071e-7,0.000099414734,0.0024932073,0.8671865,0.0000047861395,0.00014696232,0.0002631564],"study_design_scores_gemma":[0.00012966395,0.00013112581,0.044837236,0.0000117489135,0.00009085381,3.300461e-7,0.00014783912,0.005593928,0.94876856,0.0000059497647,0.00017416943,0.00010861553],"about_ca_topic_score_codex":0.000024964767,"about_ca_topic_score_gemma":0.0000062369936,"teacher_disagreement_score":0.24425597,"about_ca_system_score_codex":0.000010080285,"about_ca_system_score_gemma":0.000031979438,"threshold_uncertainty_score":0.40717626},"labels":[],"label_agreement":null},{"id":"W3027712520","doi":"10.1101/2020.05.22.110353","title":"<i>Peel-1</i> negative selection promotes screening-free CRISPR-Cas9 genome editing in <i>Caenorhabditis elegans</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Genome; CRISPR; Cas9; Biology; Genome engineering; Genome editing; Computational biology; Caenorhabditis elegans; Genetics; Gene; Negative selection","score_opus":0.008975391211672665,"score_gpt":0.23561686511357366,"score_spread":0.22664147390190098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3027712520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8893169,0.003175419,0.10218583,0.0009373225,0.001416795,0.0017245068,0.0007705709,0.00041560023,0.000057051362],"genre_scores_gemma":[0.97886944,0.00031390347,0.017388865,0.00036058057,0.002554012,0.00026144623,0.000007655189,0.00023497817,0.0000090976055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963193,0.00014573768,0.0007217665,0.0015776696,0.00039690177,0.0008386247],"domain_scores_gemma":[0.99779516,0.00003401064,0.00035489615,0.0011005587,0.00037909337,0.00033628565],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044721662,0.0007952155,0.0006534119,0.00023294835,0.00015613044,0.00019979678,0.0008587655,0.0008074611,0.000022693193],"category_scores_gemma":[0.0007225812,0.0009846513,0.0002338189,0.00059447315,0.000104279046,0.000020153839,0.0010558352,0.0011020382,0.000015585347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004758916,0.00007564366,0.0031887817,0.0003276725,0.00015712058,0.000046485897,0.000023089038,0.0016138249,0.99353397,0.00002711243,0.0009525801,0.0000061145047],"study_design_scores_gemma":[0.00096559577,0.00020641107,0.025405087,0.00026529244,0.00009098421,2.0163287e-7,0.000011325947,0.0010872417,0.9626235,0.0000062593854,0.008259856,0.0010782938],"about_ca_topic_score_codex":0.00013430777,"about_ca_topic_score_gemma":0.00005249139,"teacher_disagreement_score":0.08955256,"about_ca_system_score_codex":0.0001254396,"about_ca_system_score_gemma":0.00036032157,"threshold_uncertainty_score":0.99926037},"labels":[],"label_agreement":null},{"id":"W3027852753","doi":"10.1186/s13229-020-00333-6","title":"Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells","year":2020,"lang":"en","type":"review","venue":"Molecular Autism","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; University of Prince Edward Island","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; McLaughlin Centre, University of Toronto; GlaxoSmithKline; University of Toronto; Simons Foundation Autism Research Initiative; Simons Foundation","keywords":"Induced pluripotent stem cell; Biology; Gene; Computational biology; Genome; Genome editing; Human genome; Genetics; Human genetics; Autism spectrum disorder; Autism; Neuroscience; Medicine; Embryonic stem cell","score_opus":0.02344108395769964,"score_gpt":0.28645386863581646,"score_spread":0.26301278467811684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3027852753","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.041601036,0.94407487,0.013051363,0.000035237514,0.00023799355,0.00074125634,0.00013781418,0.000050075145,0.000070333794],"genre_scores_gemma":[0.55292964,0.4458002,0.00058605865,0.000052396488,0.000026494732,0.00005638134,0.00030454577,0.00016261333,0.00008168586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973672,0.00020659255,0.0007374297,0.0008495315,0.00039866206,0.00044058354],"domain_scores_gemma":[0.9987624,0.000009267292,0.00033185983,0.00064596714,0.00005334126,0.00019712125],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001573403,0.0006247335,0.0012239902,0.00011629547,0.00008538493,0.000033692955,0.00048663313,0.0005757067,0.000008436972],"category_scores_gemma":[0.000011477153,0.0005838125,0.00044663437,0.00022995795,0.00010270119,0.0000035376506,0.00022796872,0.00039007032,0.0000049988234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000093688395,0.000058126712,3.515474e-7,0.0012369704,0.00070028694,0.00019888827,0.000030463088,0.0035019047,0.9566443,0.00018663441,0.000020538524,0.037412148],"study_design_scores_gemma":[0.0044830325,0.0040650787,0.00022950437,0.018353358,0.007173248,0.00087757537,0.00008145881,0.0065865074,0.7996664,0.00027864808,0.15108249,0.0071227155],"about_ca_topic_score_codex":0.000038832248,"about_ca_topic_score_gemma":0.000007580258,"teacher_disagreement_score":0.5113286,"about_ca_system_score_codex":0.000053607986,"about_ca_system_score_gemma":0.00043459583,"threshold_uncertainty_score":0.9996613},"labels":[],"label_agreement":null},{"id":"W3028174036","doi":"10.1016/j.chembiol.2020.05.005","title":"CRISPR Lights up In Situ Protein Evolution","year":2020,"lang":"en","type":"letter","venue":"Cell chemical biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; In situ; Fluorescent protein; Protein evolution; Biology; Computational biology; Cas9; Directed evolution; Cell biology; Genetics; Green fluorescent protein; Chemistry; Gene","score_opus":0.006856239047882237,"score_gpt":0.2606901867723469,"score_spread":0.25383394772446466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3028174036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46532014,0.020724602,0.024615422,0.46173543,0.003647058,0.0033927006,0.00029301769,0.0003222952,0.019949345],"genre_scores_gemma":[0.9125627,0.0000860689,0.00060932833,0.077841975,0.0048369444,0.00012716852,0.0024341077,0.00008377807,0.0014179013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982682,0.00006275427,0.00032879616,0.00076814886,0.000080345904,0.0004917433],"domain_scores_gemma":[0.9994063,0.000015698952,0.000079352816,0.00038037277,0.000038227554,0.00008006864],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00004734189,0.00035495654,0.00036150424,0.00006525102,0.000020599062,0.000010666985,0.000364464,0.0015534926,0.000026363534],"category_scores_gemma":[0.00007196965,0.00034852067,0.00015539181,0.00010397639,0.00010095553,0.0000011549799,0.00021314436,0.0009847204,0.000074810545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019558747,0.000012039837,0.000021966727,0.00009880263,0.000013124902,0.000025935287,0.0000100075795,0.0000016215905,0.7590867,0.000007091979,0.24061261,0.000090499976],"study_design_scores_gemma":[0.00023689607,0.00007536412,0.000003849907,0.000014173155,0.000009479295,0.0000053638964,0.0000029300802,0.000008305055,0.59440047,0.00021983557,0.40476632,0.00025704844],"about_ca_topic_score_codex":0.000014529382,"about_ca_topic_score_gemma":0.000005047898,"teacher_disagreement_score":0.4472426,"about_ca_system_score_codex":0.000048963575,"about_ca_system_score_gemma":0.00007409589,"threshold_uncertainty_score":0.9998967},"labels":[],"label_agreement":null},{"id":"W3029194094","doi":"10.1186/s13059-020-02046-8","title":"MAUDE: inferring expression changes in sorting-based CRISPR screens","year":2020,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Klarman Cell Observatory, Broad Institute; National Institutes of Health; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"CRISPR; Sorting; Biology; Leverage (statistics); Computational biology; Expression (computer science); Gene expression; Gene; Computer science; Genetics; Artificial intelligence; Algorithm; Programming language","score_opus":0.017732184960938837,"score_gpt":0.318719065549013,"score_spread":0.3009868805880742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3029194094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9444362,0.0018834302,0.051902335,0.0010024111,0.00011660656,0.00019172298,0.00002155868,0.000038899143,0.0004068563],"genre_scores_gemma":[0.9967985,0.00008391794,0.0014484461,0.0011494998,0.0003158481,0.000023404311,0.00013719629,0.000021235015,0.000021927537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907523,0.00003930619,0.00017503426,0.00035981496,0.00004109299,0.000309524],"domain_scores_gemma":[0.9996312,0.000009252607,0.00004498328,0.00019181005,0.000022233013,0.00010050315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009366651,0.00014658566,0.00016018888,0.000053770076,0.0000320223,0.0000071006307,0.0001712851,0.00017230905,0.00004164773],"category_scores_gemma":[0.000083424464,0.00014435587,0.00004583979,0.00009264931,0.00003615312,0.0000011277164,0.0001332309,0.00010209172,0.000011418844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003820639,0.00001172867,0.01368944,0.000021537366,0.0000066587017,0.0000035600297,0.00006587943,0.0028050866,0.9824026,0.000012479473,0.000069806236,0.0008729802],"study_design_scores_gemma":[0.000776844,0.0004846629,0.018265806,0.000014364364,0.000006996798,0.0000033207914,0.00008285169,0.0011675488,0.9291838,0.000024535193,0.04965568,0.0003336142],"about_ca_topic_score_codex":0.000017782268,"about_ca_topic_score_gemma":0.00009401576,"teacher_disagreement_score":0.053218864,"about_ca_system_score_codex":0.000008747637,"about_ca_system_score_gemma":0.000028491393,"threshold_uncertainty_score":0.5886662},"labels":[],"label_agreement":null},{"id":"W3030023178","doi":"10.1111/hae.14023","title":"Uncertainty in an era of transformative therapy for haemophilia: Addressing the unknowns","year":2020,"lang":"en","type":"article","venue":"Haemophilia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Hemophilia Society","funders":"","keywords":"Haemophilia; Medicine; Clinical trial; Haemophilia A; Acknowledgement; Gene transfer; Genetic enhancement; Intensive care medicine; Transformative learning; Gene; Surgery; Computer science; Pathology; Biology; Psychology","score_opus":0.04787332188454652,"score_gpt":0.3425752217972616,"score_spread":0.29470189991271506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030023178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866246,0.0013122375,0.009689378,0.0015829736,0.00007520527,0.00049745664,0.00006335403,0.000011190216,0.00014361314],"genre_scores_gemma":[0.99855375,0.00021750949,0.00045293753,0.0004494324,0.0001838982,0.00004210258,0.000069832895,0.00001946615,0.000011078389],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999244,0.00003705457,0.00022369066,0.00021679672,0.000085287524,0.00019322216],"domain_scores_gemma":[0.9996025,0.000021265223,0.0000437071,0.0002096228,0.00005931739,0.00006360548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013926708,0.00013524591,0.00016699312,0.000016345351,0.0000505587,0.000012598246,0.0002198121,0.000088371875,0.000009973233],"category_scores_gemma":[0.000039127866,0.00010156868,0.00009304096,0.00011108179,0.0000709541,0.0000057363527,0.000023243427,0.0001209065,7.934948e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006756808,0.000106313244,0.0008046438,0.000121635014,0.000068820606,0.0000026667262,0.0058691837,0.034689177,0.89904404,0.0001863884,0.0005992981,0.05783218],"study_design_scores_gemma":[0.0029999826,0.0014922539,0.008970381,0.00007027993,0.000025285493,0.000007193267,0.0013274576,0.02139785,0.945233,0.00047661705,0.017562777,0.0004369552],"about_ca_topic_score_codex":0.000012598088,"about_ca_topic_score_gemma":0.000055602548,"teacher_disagreement_score":0.057395227,"about_ca_system_score_codex":0.0000062360855,"about_ca_system_score_gemma":0.000045083823,"threshold_uncertainty_score":0.41418505},"labels":[],"label_agreement":null},{"id":"W3030181293","doi":"10.1038/s41467-020-16542-9","title":"Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Science Foundation; National Institutes of Health; U.S. Department of Health and Human Services; National Cancer Institute; National Institute of General Medical Sciences; Canadian Institute for Advanced Research","keywords":"CRISPR; Genome editing; Cas9; Guide RNA; Computational biology; Cleavage (geology); Computer science; Genome engineering; RNA; Biology; Genetics; Gene","score_opus":0.0133752239792848,"score_gpt":0.3556321362887498,"score_spread":0.342256912309465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030181293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9006122,0.010991986,0.06406888,0.0101453215,0.000271577,0.0008416128,0.0006538592,0.00010379359,0.012310803],"genre_scores_gemma":[0.99338144,0.00016596868,0.0051562632,0.00013957458,0.000058714508,0.0000071953705,0.0010496493,0.00001548355,0.000025739208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992119,0.000050602062,0.00034751472,0.00015397508,0.00013045508,0.00010553977],"domain_scores_gemma":[0.99888086,0.00006112921,0.00016544868,0.0006292648,0.00020258572,0.000060716073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222,0.000101031634,0.0001426091,0.000024817567,0.00009818559,0.0000069915723,0.0005003131,0.00022280526,0.0000065002755],"category_scores_gemma":[0.0007514241,0.000103792096,0.000049450657,0.00015672742,0.00008080854,0.0000053084595,0.00031613957,0.00029600505,5.920305e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028988801,0.000050607403,0.0007581455,0.000033499895,0.000028833194,1.666629e-7,0.00013405089,0.00003897651,0.9890739,0.0000998144,0.009225041,0.0005279769],"study_design_scores_gemma":[0.00023623402,0.00013673249,0.0009801945,0.000032620337,0.000021118774,0.0000031047691,0.00020574992,0.001376253,0.9753138,0.000006150512,0.021596909,0.00009115246],"about_ca_topic_score_codex":0.000011754062,"about_ca_topic_score_gemma":0.00002009695,"teacher_disagreement_score":0.09276925,"about_ca_system_score_codex":0.000008346548,"about_ca_system_score_gemma":0.000059776066,"threshold_uncertainty_score":0.42325187},"labels":[],"label_agreement":null},{"id":"W3030310275","doi":"10.1021/acssynbio.0c00148","title":"Dynamic Cell Programming with Quorum Sensing-Controlled CRISPRi Circuit","year":2020,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Ontario Ministry of Research, Innovation and Science","keywords":"Quorum sensing; Synthetic biology; Biomanufacturing; Computer science; Computational biology; Systems biology; Population; Biology; Biochemical engineering; Biotechnology; Engineering; Bacteria; Genetics; Biofilm","score_opus":0.006910286148679296,"score_gpt":0.26364390772042756,"score_spread":0.2567336215717483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030310275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83642614,0.002180815,0.15746102,0.0016374646,0.00020233165,0.00061657035,0.000013828764,0.00009516029,0.0013666985],"genre_scores_gemma":[0.9952556,0.00008904071,0.003722552,0.0005751829,0.00011441254,0.000021026235,0.000050145387,0.00004575104,0.00012627507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860615,0.00006779843,0.00024818408,0.0005413476,0.00007457177,0.00046195666],"domain_scores_gemma":[0.9993342,0.00003100748,0.00008062913,0.00034164742,0.00006001193,0.00015247067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011887084,0.0002567359,0.00034298777,0.000035883913,0.0000732941,0.000022472334,0.0002084625,0.00022301202,0.000017878814],"category_scores_gemma":[0.00008300328,0.00020855574,0.00010398719,0.00010377158,0.00012534732,0.0000018642911,0.00009973354,0.00014998796,0.000028888857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025417053,0.000039655995,0.00046882595,0.000038402555,0.000099849305,0.0000102636095,0.00015477884,0.00026116724,0.9813011,0.00007401541,0.00009627183,0.017201489],"study_design_scores_gemma":[0.009349697,0.0039041154,0.0005303064,0.00005435917,0.0003206437,0.0002478668,0.00083013874,0.005653031,0.8603312,0.00016259385,0.1170662,0.0015498771],"about_ca_topic_score_codex":0.00001555367,"about_ca_topic_score_gemma":0.000021858466,"teacher_disagreement_score":0.1588295,"about_ca_system_score_codex":0.000009850711,"about_ca_system_score_gemma":0.000053044336,"threshold_uncertainty_score":0.8504656},"labels":[],"label_agreement":null},{"id":"W3030499850","doi":"10.1101/2020.05.28.119941","title":"An anti-CRISPR protein induces strong non-specific DNA binding activity in a CRISPR-Cas complex","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; DNA; Nucleic acid; Cleave; RNA; Biology; Computational biology; Genome editing; Function (biology); Genetics; Guide RNA; Gene","score_opus":0.02420738798667988,"score_gpt":0.2825219379461828,"score_spread":0.2583145499595029,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030499850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97680426,0.0005300007,0.020428095,0.00014352307,0.0004952589,0.001211942,0.00023578003,0.00014049548,0.0000106465295],"genre_scores_gemma":[0.99427664,0.00023358446,0.004135355,0.000052939777,0.000840366,0.0002507945,0.0000065169843,0.0002018389,0.0000019777947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963549,0.00016592513,0.0005763999,0.0017098357,0.00036741627,0.00082552497],"domain_scores_gemma":[0.9976114,0.000013786942,0.00030346433,0.0014766324,0.00018920847,0.00040549226],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004478539,0.00081179757,0.00075115217,0.0002987563,0.0001439355,0.00026660215,0.0008711752,0.0008124104,0.000023838762],"category_scores_gemma":[0.00007798907,0.00096729933,0.00020237855,0.000458067,0.00011173963,0.000025115956,0.00071111997,0.0010134238,0.000025624991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057865946,0.00019091426,0.0026489566,0.00030264788,0.00009433493,0.000057659534,0.000020091855,0.0004930375,0.9959385,0.000028841372,0.0001544694,0.000012686337],"study_design_scores_gemma":[0.0005872144,0.00015182616,0.12483715,0.00021107921,0.00002907546,4.0759403e-8,0.00001288306,0.0007731911,0.8708009,5.2694924e-7,0.001661537,0.0009345474],"about_ca_topic_score_codex":0.00008078353,"about_ca_topic_score_gemma":0.000015725247,"teacher_disagreement_score":0.12513757,"about_ca_system_score_codex":0.00015263181,"about_ca_system_score_gemma":0.0003194572,"threshold_uncertainty_score":0.9992778},"labels":[],"label_agreement":null},{"id":"W3030735207","doi":"10.1038/s41467-020-16512-1","title":"AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Office of Extramural Research, National Institutes of Health; Thailand Science Research and Innovation; Simons Foundation; Life Sciences Research Foundation; National Institute of Biomedical Imaging and Bioengineering; Montana State University; Amgen; U.S. Department of Health and Human Services; National Institutes of Health; M.J. Murdock Charitable Trust; National Institute of Food and Agriculture; Damon Runyon Cancer Research Foundation; U.S. Department of Agriculture","keywords":"CRISPR; RNA; Computational biology; Biology; Trans-activating crRNA; DNA; Acquired immune system; Guide RNA; Oligonucleotide; Immune system; Cas9; CRISPR interference; Genetics; Gene","score_opus":0.050514531895096686,"score_gpt":0.3676702678100953,"score_spread":0.3171557359149986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030735207","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26829594,0.060448423,0.15532093,0.4617085,0.0016600045,0.0035278732,0.00075574324,0.00038547264,0.04789714],"genre_scores_gemma":[0.98578286,0.0011053601,0.007945294,0.0046312325,0.00022749456,0.000033050157,0.00017906878,0.000022771232,0.00007284829],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99921495,0.000070312235,0.00017252835,0.00024183087,0.00011347944,0.00018690417],"domain_scores_gemma":[0.9980682,0.000048722024,0.000039300907,0.0016144156,0.00011649691,0.00011285534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014998256,0.0001341388,0.00011203138,0.000018219265,0.00020188304,0.000036616275,0.0014598892,0.00014797103,0.00002012996],"category_scores_gemma":[0.00018127143,0.00011200894,0.00007241472,0.00025155375,0.0000804676,0.000002405465,0.00044453354,0.00041522924,0.0000483956],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011821853,0.000018758208,0.0006366027,0.0000062659187,0.000030019968,5.510276e-7,0.00032443323,0.0011259245,0.80054295,0.00035406448,0.1953983,0.0015503097],"study_design_scores_gemma":[0.00016365672,0.000047568214,0.010305207,0.000005684351,0.0000055904065,0.0000053330646,0.0001795338,0.0009026538,0.039287273,0.0000092997625,0.9489043,0.0001839449],"about_ca_topic_score_codex":0.000011224719,"about_ca_topic_score_gemma":0.00014589337,"teacher_disagreement_score":0.7612557,"about_ca_system_score_codex":0.000012621695,"about_ca_system_score_gemma":0.000031997548,"threshold_uncertainty_score":0.45675918},"labels":[],"label_agreement":null},{"id":"W3032385310","doi":"10.1093/nar/gkaa474","title":"Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription","year":2020,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Vetenskapsrådet; Cancerfonden; Wellcome Trust","keywords":"Biology; Transcription (linguistics); Transcription factor; Genetics; Molecular biology; Cancer research; Gene","score_opus":0.03868006816398308,"score_gpt":0.3599983973504086,"score_spread":0.32131832918642556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3032385310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830807,0.00042533485,0.01167145,0.0035010446,0.00006621958,0.00040862832,0.00003649981,0.00002404578,0.0007860993],"genre_scores_gemma":[0.996785,0.00012028471,0.0016874057,0.00061018486,0.00033992837,0.000028028931,0.00002283498,0.00003768915,0.00036867007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998409,0.000080986465,0.00016900367,0.0005057772,0.00035448832,0.0004807871],"domain_scores_gemma":[0.9990841,0.000016843687,0.000008842597,0.0002569774,0.00012564013,0.0005075927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032064202,0.00014674479,0.000151932,0.000088662404,0.00011635955,0.00007014281,0.00023825436,0.00012958197,0.000106581094],"category_scores_gemma":[0.00011178826,0.00014861253,0.000051726623,0.00026357197,0.00006166184,0.00000463107,0.0002039813,0.00021701054,0.00008491881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021251457,0.000021747861,0.00031437323,0.00004497905,0.000019978272,0.000013932799,0.00077499123,0.00032779865,0.9794063,0.000020447504,0.01123817,0.0076047573],"study_design_scores_gemma":[0.0005927282,0.0012082389,0.006668985,0.000025424191,0.0000092252885,0.000016791124,0.0004300789,0.0012365251,0.83810025,0.000014710538,0.15141793,0.00027909226],"about_ca_topic_score_codex":0.00002751106,"about_ca_topic_score_gemma":0.000016581875,"teacher_disagreement_score":0.14130604,"about_ca_system_score_codex":0.000012763714,"about_ca_system_score_gemma":0.000034754354,"threshold_uncertainty_score":0.60602427},"labels":[],"label_agreement":null},{"id":"W3033123873","doi":"10.1016/j.omtn.2020.05.030","title":"CRISPR-Cas13a Inhibits HIV-1 Infection","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Peking Union Medical College; Canadian Institutes of Health Research; Chinese Academy of Medical Sciences; National Natural Science Foundation of China; Chinese Academy of Meteorological Sciences; Ministry of Science and Technology of the People's Republic of China","keywords":"CRISPR; Biology; RNA; Effector; Plasmid; Trans-activating crRNA; Virology; DNA; Gene; Cas9; Genetics; Cell biology","score_opus":0.01045312759101866,"score_gpt":0.2709161115900577,"score_spread":0.260462983999039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033123873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8556794,0.001692891,0.14011587,0.00090635096,0.00014100403,0.00020847227,0.000008682538,0.0000790169,0.0011683118],"genre_scores_gemma":[0.99475276,0.00054080744,0.0010779186,0.0030187464,0.00031500022,0.000020676945,0.00007950759,0.0000722894,0.0001222809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988465,0.00004778228,0.00020663021,0.00043704297,0.00016751523,0.00029456205],"domain_scores_gemma":[0.9993837,0.0000033713306,0.000045278284,0.00033792268,0.000055650373,0.00017408337],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007901042,0.00024294804,0.00016826879,0.000037759182,0.00007048631,0.000040938652,0.0001758898,0.00017821624,0.00009518776],"category_scores_gemma":[0.00003999738,0.00025026593,0.00016632058,0.00017377721,0.000043969063,0.000004955711,0.00009251487,0.0001452386,0.00011632283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069736656,0.000033428118,0.0014188649,0.00001249108,0.00007286186,0.000011352013,0.00015652135,0.0010308293,0.98831403,0.00005239215,0.0018351588,0.006992303],"study_design_scores_gemma":[0.00079822924,0.00035125134,0.0019676753,0.0000064623787,0.000011676801,0.0000149054185,0.000017936933,0.00033429015,0.83485097,0.000025777563,0.1613352,0.00028564606],"about_ca_topic_score_codex":0.000008654692,"about_ca_topic_score_gemma":0.000001736765,"teacher_disagreement_score":0.15950005,"about_ca_system_score_codex":0.000010952193,"about_ca_system_score_gemma":0.00002793343,"threshold_uncertainty_score":0.99999493},"labels":[],"label_agreement":null},{"id":"W3033205583","doi":"10.1101/2020.06.04.134841","title":"GO-CRISPR: a highly controlled workflow to discover gene essentiality in loss-of-function screens","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Western University","funders":"","keywords":"CRISPR; Workflow; Function (biology); Computational biology; Biology; Loss function; Gene; Computer science; Genetics; Database; Phenotype","score_opus":0.00952600741281796,"score_gpt":0.253233084511127,"score_spread":0.24370707709830908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033205583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8967455,0.0013269838,0.09904838,0.00033767484,0.0010644285,0.0011466284,0.00024922198,0.000068605215,0.000012547001],"genre_scores_gemma":[0.9927252,0.00024284323,0.005754507,0.00023151726,0.0007184833,0.00020829265,0.0000043208424,0.000107202824,0.000007617055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972865,0.00011601347,0.00072927214,0.001082865,0.00030547832,0.00047987778],"domain_scores_gemma":[0.9980872,0.00002199686,0.00025156312,0.0011093388,0.00024501144,0.0002848746],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041192316,0.00053229945,0.0008189158,0.00018902599,0.000046207177,0.00007848406,0.00045531747,0.0005402321,0.000015972297],"category_scores_gemma":[0.0002790934,0.0005824937,0.00029746964,0.0003946746,0.00006792264,0.0000074070435,0.0006287478,0.0004119631,0.000019857247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006964465,0.000116118965,0.0086500235,0.00021247078,0.0002496555,0.000020034973,0.0000061399073,0.0033693663,0.9862706,0.000098110555,0.0003071208,0.0000038781277],"study_design_scores_gemma":[0.0025212339,0.00017841089,0.077294186,0.00019839902,0.00016758151,2.0113083e-8,0.000002373248,0.00042271795,0.91526777,0.00000479955,0.003203156,0.0007393793],"about_ca_topic_score_codex":0.000074905984,"about_ca_topic_score_gemma":0.000022070586,"teacher_disagreement_score":0.09597968,"about_ca_system_score_codex":0.0000724142,"about_ca_system_score_gemma":0.00033472636,"threshold_uncertainty_score":0.99966264},"labels":[],"label_agreement":null},{"id":"W3033505600","doi":"10.1016/j.scr.2020.101852","title":"Rates of homology directed repair of CRISPR-Cas9 induced double strand breaks are lower in naïve compared to primed human pluripotent stem cells","year":2020,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Oxford Martin School, University of Oxford; Innovative Medicines Initiative; European Commission; University of Oxford; Parkinson's UK; National Institute for Health and Care Research; Medical Research Council; Seventh Framework Programme; European Federation of Pharmaceutical Industries and Associations; Stem Cell Network; Biotechnology and Biological Sciences Research Council; University Hospitals; Wellcome Trust; Roche","keywords":"CRISPR; Biology; Induced pluripotent stem cell; Genome editing; Homology directed repair; Cas9; Gene; Homology (biology); Homologous recombination; Genetics; Cell biology; Molecular biology; Computational biology; DNA repair; Embryonic stem cell; Nucleotide excision repair","score_opus":0.07184285759221691,"score_gpt":0.38074886762279747,"score_spread":0.30890601003058055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033505600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974541,0.0007281258,0.00014222469,0.00008217464,0.000073003386,0.00067325495,0.000029309473,0.00002013429,0.000797651],"genre_scores_gemma":[0.9992085,0.000042598804,0.00012906673,0.000018209224,0.000054828142,0.00003342872,0.000018861552,0.000031008825,0.00046346412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980671,0.00018254227,0.00046914892,0.00049218815,0.00034029727,0.00044874882],"domain_scores_gemma":[0.99890107,0.000047874288,0.000081424776,0.00043267987,0.00032879543,0.00020818524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004735367,0.00017417122,0.00039318457,0.00015907978,0.000045304067,0.0000121720195,0.00033100712,0.00018840577,0.000026348544],"category_scores_gemma":[0.000011425839,0.0001748563,0.00010952539,0.000421025,0.000081281396,0.0000029576636,0.000258761,0.00026550432,0.000006873905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057214266,0.00015431504,0.0021367162,0.00033840942,0.000043748718,0.000021999993,0.00055578613,0.00091854704,0.9942691,0.000005146723,0.0007938239,0.00019030548],"study_design_scores_gemma":[0.0014675093,0.00080629246,0.005449473,0.00005532596,0.000008303572,0.0000013157523,0.000868016,0.00021792673,0.99002993,0.0000018995606,0.0009332265,0.0001607883],"about_ca_topic_score_codex":0.00022869548,"about_ca_topic_score_gemma":0.00018929332,"teacher_disagreement_score":0.0042391354,"about_ca_system_score_codex":0.000026120797,"about_ca_system_score_gemma":0.000106579944,"threshold_uncertainty_score":0.7130433},"labels":[],"label_agreement":null},{"id":"W3033735360","doi":"10.1016/j.molcel.2020.05.021","title":"Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; National Research Council Canada; Mount Sinai Hospital","funders":"Basic Energy Sciences; National Institute of Environmental Health Sciences; Medical Research Council; Canada Research Chairs; National Institutes of Health; Office of Science; Department of Energy, Labor and Economic Growth; National Center for Research Resources; Krembil Foundation; Argonne National Laboratory; U.S. Department of Energy; European Molecular Biology Organization; Canadian Cancer Society; Canadian Institutes of Health Research; National Research Council","keywords":"Biology; Nuclease; Endogeny; DNA; Genetics; Cell biology; Computational biology; Molecular biology; Biochemistry","score_opus":0.00969186557819323,"score_gpt":0.21997487695582926,"score_spread":0.21028301137763603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033735360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9717453,0.014127132,0.0119702695,0.0010255898,0.000045356235,0.00039016033,0.00008985748,0.000018183711,0.0005881626],"genre_scores_gemma":[0.99793166,0.00017737133,0.00043372638,0.0011736964,0.000059022917,0.000027420338,0.00002901702,0.000029306262,0.00013878757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918336,0.000027590782,0.00012643171,0.00036150205,0.000080974765,0.00022014072],"domain_scores_gemma":[0.99955976,0.000017443828,0.000048065613,0.0002221673,0.000035968704,0.00011658476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000074703596,0.0001622185,0.00013179776,0.000010849913,0.00011857456,0.00003879377,0.00012211512,0.00008637979,0.0000073248452],"category_scores_gemma":[0.00008047908,0.0001394765,0.00006407122,0.000043375545,0.00007802569,0.00000181766,0.00009497525,0.00007526272,0.0000011387161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002816396,0.000021954807,0.00021672115,0.00011749387,0.000016546912,0.00000848892,0.0002510974,0.00017066658,0.9955953,0.000012567105,0.0029288956,0.0006321054],"study_design_scores_gemma":[0.000845487,0.00026065912,0.00012622657,0.00000928351,0.0000582035,0.000022835662,0.0010833123,0.00059223484,0.94478303,0.000044798024,0.051896263,0.00027764667],"about_ca_topic_score_codex":0.000008665924,"about_ca_topic_score_gemma":0.000004483444,"teacher_disagreement_score":0.05081225,"about_ca_system_score_codex":0.0000047815024,"about_ca_system_score_gemma":0.000017787426,"threshold_uncertainty_score":0.5687687},"labels":[],"label_agreement":null},{"id":"W3033805182","doi":"10.1007/s11192-020-03537-y","title":"Gatekeepers in knowledge transfer between science and technology: an exploratory study in the area of gene editing","year":2020,"lang":"en","type":"article","venue":"Scientometrics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Natural Science Foundation of China","keywords":"Betweenness centrality; Knowledge flow; Social network analysis; Knowledge transfer; Computer science; Data science; Knowledge management; World Wide Web; Centrality; Social media","score_opus":0.042753495327502666,"score_gpt":0.33993385302328943,"score_spread":0.29718035769578677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033805182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99789506,0.00071483303,0.00095330086,0.000102102036,0.000045266064,0.000185183,0.000004790701,0.0000055118935,0.00009395548],"genre_scores_gemma":[0.9997543,0.000020555628,0.00013657128,0.000025994825,0.000045157845,0.000008909782,0.0000023492007,0.0000052153864,9.2201543e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905384,0.00002747325,0.00015570378,0.00030212014,0.00026674752,0.0001941201],"domain_scores_gemma":[0.9996057,0.000015507389,0.000013909512,0.00018011156,0.000118960896,0.00006579202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014569345,0.000072489864,0.00010215293,0.0010250715,0.00004263985,0.000022708065,0.0003788413,0.00004966682,5.025621e-7],"category_scores_gemma":[0.00057272287,0.00006049585,0.000010349742,0.009155121,0.00020761573,0.000008479092,0.000082615894,0.00009721177,2.9561454e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000046156847,0.00013048958,0.47856554,0.000019279983,0.000004500421,0.000003288938,0.0086007295,0.00017938425,0.5029861,0.000011852299,0.000012154742,0.009482079],"study_design_scores_gemma":[0.0013220495,0.0012755768,0.32548314,0.000015309224,0.000017344553,0.0000027969986,0.033009402,0.0012873005,0.6367018,0.000011782927,0.0006045575,0.0002688837],"about_ca_topic_score_codex":0.0000027557724,"about_ca_topic_score_gemma":0.000045710585,"teacher_disagreement_score":0.1530824,"about_ca_system_score_codex":0.00001242543,"about_ca_system_score_gemma":0.000080116064,"threshold_uncertainty_score":0.43987322},"labels":[],"label_agreement":null},{"id":"W3034021106","doi":"10.1016/j.scr.2020.101856","title":"Generation of two patient-derived iPSC lines from siblings (LIBUCi001-A and LIBUCi002-A) and a genetically modified iPSC line (JMUi001-A-1) to mimic dilated cardiomyopathy with ataxia (DCMA) caused by a homozygous DNAJC19 mutation","year":2020,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Libin Cardiovascular Institute of Alberta","funders":"Bundesministerium für Bildung und Forschung","keywords":"Induced pluripotent stem cell; Biology; Germ layer; Sendai virus; CRISPR; Ataxia; Reprogramming; Karyotype; Mutation; Dilated cardiomyopathy; Cardiomyopathy; Cell culture; Cell biology; Molecular biology; Cancer research; Genetics; Internal medicine; Embryonic stem cell; Cell; Chromosome; Heart failure; Gene; Neuroscience; Medicine","score_opus":0.0426946599574335,"score_gpt":0.31861974787821684,"score_spread":0.27592508792078335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034021106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801336,0.0036561093,0.014999453,0.0002637863,0.000029345942,0.00067193585,0.00016249201,0.000026808206,0.000056471457],"genre_scores_gemma":[0.9968718,0.00048019123,0.0018345319,0.00010717897,0.00017928408,0.000055932607,0.0003605456,0.000055864686,0.000054647833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979941,0.00014981178,0.0003464449,0.00070146134,0.00042125786,0.0003868842],"domain_scores_gemma":[0.9988917,0.00004991274,0.0000681911,0.00028427568,0.0003630262,0.00034286783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021476932,0.00023970388,0.00029906636,0.000121591096,0.00011448182,0.0000839686,0.0001540841,0.00015683708,0.0000060107677],"category_scores_gemma":[0.000042181466,0.00022487149,0.000041906365,0.0003565894,0.000118158416,0.000009650291,0.0002294345,0.0001954254,0.000003022145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002777301,0.000041858202,0.000288934,0.000082859806,0.00005999984,0.000018511224,0.0010096538,0.004266559,0.98742825,0.0000014055345,0.00046788141,0.006056346],"study_design_scores_gemma":[0.0015698257,0.0019095454,0.00033364078,0.000032577133,0.000043859352,0.000007211062,0.0003732392,0.028078336,0.9666822,0.0000048459024,0.00068555574,0.00027918638],"about_ca_topic_score_codex":0.00015051324,"about_ca_topic_score_gemma":0.000091855094,"teacher_disagreement_score":0.023811778,"about_ca_system_score_codex":0.000014247846,"about_ca_system_score_gemma":0.00008659722,"threshold_uncertainty_score":0.9169993},"labels":[],"label_agreement":null},{"id":"W3034739500","doi":"10.1186/s13059-020-02051-x","title":"SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds","year":2020,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"Chinese Academy of Sciences; Institute of Microbiology, Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Genome editing; CRISPR; Biology; Cas9; Cytidine deaminase; RNA editing; Computational biology; Guide RNA; Indel; Genetics; RNA; DNA; Gene","score_opus":0.009938021214321496,"score_gpt":0.2662095425051744,"score_spread":0.25627152129085295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034739500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912026,0.0036653904,0.0042801993,0.00028679572,0.000082876686,0.0002130222,0.00014110885,0.000025364752,0.00010265367],"genre_scores_gemma":[0.996885,0.0002367679,0.0014978218,0.00032685118,0.0005542828,0.000026357013,0.00041906492,0.000032805536,0.000021017571],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987383,0.000036742364,0.00024587288,0.0005057614,0.00005764866,0.00041567322],"domain_scores_gemma":[0.99953234,0.000017132856,0.000051103165,0.00018462268,0.000027635506,0.00018717807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106487016,0.00023340184,0.0002581135,0.000067712055,0.000042648007,0.000013599737,0.00015286096,0.00019609534,0.000024449497],"category_scores_gemma":[0.00004298769,0.00021527715,0.000040792125,0.000093465685,0.00006945632,0.0000032954858,0.00013491181,0.00010438733,0.0000066718667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012804111,0.000017702183,0.0064516794,0.000033588563,0.000049457463,0.00003261647,0.00024224784,0.001264549,0.9911644,0.000016201633,0.00002718958,0.0005723165],"study_design_scores_gemma":[0.015049869,0.006286745,0.34406397,0.00010395139,0.00014603352,0.000819082,0.002294042,0.006783446,0.49802497,0.00010572209,0.1225783,0.0037438816],"about_ca_topic_score_codex":0.00003008607,"about_ca_topic_score_gemma":0.0001235642,"teacher_disagreement_score":0.49313945,"about_ca_system_score_codex":0.000011806537,"about_ca_system_score_gemma":0.000042881948,"threshold_uncertainty_score":0.87787473},"labels":[],"label_agreement":null},{"id":"W3034852933","doi":"10.1038/s41587-020-0587-z","title":"Publisher Correction: Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing","year":2020,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"CRISPR; Genome editing; Epigenetics; Computational biology; Biology; Genetics; Gene","score_opus":0.003451073510145323,"score_gpt":0.22512850544146673,"score_spread":0.22167743193132142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034852933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8348538,0.014159028,0.14459567,0.004139236,0.0011881761,0.0007312639,0.000051139035,0.00020855945,0.000073122326],"genre_scores_gemma":[0.98317605,0.000283327,0.015433154,0.00039339234,0.00050244277,0.000049321636,0.000076282835,0.000042075244,0.00004394829],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989802,0.000017777507,0.00014452054,0.00050738984,0.00006303752,0.00028707],"domain_scores_gemma":[0.9995625,0.00003953232,0.000060393344,0.00017350905,0.000060066268,0.00010401723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093689,0.00021953373,0.00021000896,0.000074273645,0.000097986165,0.000045846926,0.00011034898,0.0007898441,0.0000031281306],"category_scores_gemma":[0.00046500744,0.00020231097,0.000033024608,0.00012938662,0.00009253287,0.000009463982,0.000103478815,0.00036455205,1.366453e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014810289,0.00001224734,0.0003603628,0.00007849394,0.000074485426,0.0000042345564,0.000048598235,0.00005002431,0.99025226,0.00002770657,0.0035512554,0.0053922315],"study_design_scores_gemma":[0.0013637376,0.0006774338,0.000807308,0.000016258351,0.000056929315,0.00007487561,0.00036667884,0.004671898,0.9738007,0.000020034577,0.01781766,0.00032645196],"about_ca_topic_score_codex":0.00001113967,"about_ca_topic_score_gemma":0.000019151717,"teacher_disagreement_score":0.14832225,"about_ca_system_score_codex":0.00000705672,"about_ca_system_score_gemma":0.000032820495,"threshold_uncertainty_score":0.82500017},"labels":[],"label_agreement":null},{"id":"W3035259135","doi":"10.1101/2020.06.15.151498","title":"Mobile element warfare via CRISPR and anti-CRISPR in <i>Pseudomonas aeruginosa</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; University of California, San Francisco; University of Toronto; Montana State University; Sandler Foundation; Innovative Genomics Institute; Vallee Foundation; Howard Hughes Medical Institute","keywords":"CRISPR; Mobile genetic elements; Trans-activating crRNA; Pseudomonas aeruginosa; Biology; Mutagenesis; Transposable element; Genetics; DNA; Computational biology; Genome; Cas9; Bacteria; Gene; Mutation","score_opus":0.007934127064310948,"score_gpt":0.24674863518414494,"score_spread":0.23881450811983398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035259135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9652223,0.011122085,0.021285003,0.00019965602,0.00073681294,0.0010740984,0.00021429374,0.0001316994,0.000014075861],"genre_scores_gemma":[0.9919916,0.0026887432,0.0040032547,0.00032986669,0.0005162436,0.00031398257,0.000004274206,0.00014756787,0.0000045143706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970285,0.00008348666,0.00058861217,0.0013746544,0.00028063403,0.00064410956],"domain_scores_gemma":[0.9982566,0.000013491802,0.00018408032,0.001042791,0.00016445071,0.00033853404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030024623,0.000672535,0.0006046967,0.00015759132,0.000083966304,0.0001150096,0.00047805696,0.0005969625,0.000016760465],"category_scores_gemma":[0.00007785612,0.00078045373,0.00015467413,0.00025149898,0.00009295425,0.000009063101,0.0010110674,0.0006266584,0.000016603934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028784856,0.00009158376,0.008567843,0.00042014496,0.00010416176,0.00005946603,0.000018351162,0.00083455385,0.98905534,0.000022996885,0.0007839628,0.000012840143],"study_design_scores_gemma":[0.0008190744,0.00017374993,0.022073863,0.00016440499,0.0000760452,1.1387767e-7,0.000010805446,0.0006924239,0.9475663,0.0000017863746,0.02742903,0.0009924414],"about_ca_topic_score_codex":0.000059511345,"about_ca_topic_score_gemma":0.000009075522,"teacher_disagreement_score":0.04148905,"about_ca_system_score_codex":0.00007096339,"about_ca_system_score_gemma":0.00021721015,"threshold_uncertainty_score":0.99946463},"labels":[],"label_agreement":null},{"id":"W3035584768","doi":"10.1101/2020.06.15.153072","title":"PKIS Deep Dive Yields a Chemical Starting Point for Dark Kinases and a Cell Active BRSK2 Inhibitor","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Novartis Pharma; Gillings School of Public Health; Genentech; National Institutes of Health; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Ontario Ministry of Economic Development and Innovation; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; North Carolina Biotechnology Center; GlaxoSmithKline; Pfizer","keywords":"Kinome; Druggability; Kinase; Drug discovery; Computational biology; Phosphorylation; Chemistry; Computer science; Biology; Biochemistry; Gene","score_opus":0.008559042155874505,"score_gpt":0.23581889462384642,"score_spread":0.22725985246797192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035584768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97049856,0.0022426134,0.025205595,0.00026364197,0.0004273759,0.0008563627,0.00039564865,0.0000983412,0.00001187733],"genre_scores_gemma":[0.9885431,0.00021047353,0.009607259,0.00027702944,0.000959189,0.0002692552,0.0000046011482,0.00012634695,0.0000027812014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977858,0.000037808804,0.00039366604,0.0011029985,0.00018159341,0.0004981256],"domain_scores_gemma":[0.99858177,0.000049647013,0.00021274242,0.00059917086,0.00024089713,0.0003157849],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018284176,0.0005192676,0.00045169372,0.00007302608,0.00010445842,0.00011380189,0.00029403745,0.0005855095,0.0000057442076],"category_scores_gemma":[0.00039026,0.0005866647,0.00019221446,0.00011932262,0.0000884371,0.00000782259,0.00082495756,0.000429108,0.0000031726045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012647711,0.000060357354,0.00028629418,0.00051270396,0.000121223624,0.000010542206,0.000033289845,0.00007009857,0.99816215,0.0000140957045,0.00059135095,0.000011424162],"study_design_scores_gemma":[0.00066617806,0.000172689,0.0010850654,0.00012511668,0.00012496673,3.0067383e-8,0.000022012262,0.0005802936,0.9947616,0.0000051045586,0.0017819224,0.0006750308],"about_ca_topic_score_codex":0.000016767137,"about_ca_topic_score_gemma":0.0000025679726,"teacher_disagreement_score":0.01804452,"about_ca_system_score_codex":0.000058346362,"about_ca_system_score_gemma":0.00020562092,"threshold_uncertainty_score":0.99965847},"labels":[],"label_agreement":null},{"id":"W3035599419","doi":"10.1016/j.xpro.2020.100053","title":"Protocol for Genome Editing to Produce Multiple Mutants in Wheat","year":2020,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Bio-oriented Technology Research Advancement Institution; Japan Society for the Promotion of Science; National Agriculture and Food Research Organization; Cabinet Office, Government of Japan; Swine Innovation Porc","keywords":"Genome editing; CRISPR; Mutant; Genome; Biology; Protocol (science); Genetics; Computational biology; Gene; Cas9; Transgene; Computer science; Medicine","score_opus":0.039872480882929294,"score_gpt":0.38391483749570526,"score_spread":0.344042356612776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035599419","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012378601,0.0000026194516,0.014201206,0.0005306184,0.000019580313,0.9726443,0.00004402387,0.000028531591,0.00015049477],"genre_scores_gemma":[0.04081294,5.816859e-8,0.00872712,0.00031928383,0.0006631304,0.94936025,0.000018710283,0.00003550354,0.000063004554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988766,0.000019697847,0.00024392565,0.00043792266,0.00009926603,0.00032263572],"domain_scores_gemma":[0.99952954,0.000007661848,0.000036936046,0.0002263403,0.000060159036,0.00013938671],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015994566,0.0001559556,0.00015012363,0.000029597026,0.000038658316,0.000025530133,0.00018803724,0.00007529077,0.000014998637],"category_scores_gemma":[0.00032055363,0.00015506327,0.000050545008,0.0001203898,0.000011455655,0.0000033970312,0.00010416051,0.00007229442,0.000009611488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038212843,0.000045293556,0.0013918532,0.00035741285,0.000008400115,0.000002346199,0.0002268198,0.0012358128,0.99332124,0.0000035634175,0.0010982662,0.0019268496],"study_design_scores_gemma":[0.0019648876,0.00081599405,0.0014069943,0.00005988311,0.0000014892829,0.0000014873751,0.000053212614,0.0005537499,0.627252,0.000010829917,0.36766824,0.00021125001],"about_ca_topic_score_codex":0.0000040668424,"about_ca_topic_score_gemma":0.00002979943,"teacher_disagreement_score":0.36657,"about_ca_system_score_codex":0.000014568317,"about_ca_system_score_gemma":0.00005985018,"threshold_uncertainty_score":0.6323297},"labels":[],"label_agreement":null},{"id":"W3036187761","doi":"10.1093/nar/gkaa518","title":"IncC conjugative plasmids and SXT/R391 elements repair double-strand breaks caused by CRISPR–Cas during conjugation","year":2020,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Simon Fraser University","keywords":"Biology; CRISPR; Plasmid; Genetics; Genome editing; DNA; Computational biology; Molecular biology; Gene","score_opus":0.027374728380291473,"score_gpt":0.3524631148385412,"score_spread":0.3250883864582497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036187761","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961604,0.00061019335,0.00095316645,0.00062398636,0.000050288258,0.0004411646,0.000054502474,0.00007275908,0.0010335572],"genre_scores_gemma":[0.99839747,0.00036115758,0.00040004123,0.00012911059,0.00020124155,0.000041735693,0.00008641186,0.0000554842,0.00032733678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981161,0.00009707562,0.00029222088,0.00057757436,0.0004219857,0.0004950658],"domain_scores_gemma":[0.9991754,0.000031720643,0.000041541392,0.00027003314,0.00018372377,0.00029756007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003887232,0.00019912678,0.00019220714,0.00006674671,0.00022820884,0.00007037274,0.00019991182,0.00019517643,0.00007756861],"category_scores_gemma":[0.00013047757,0.00020694798,0.00006123555,0.00020525105,0.00020111688,0.00001213035,0.00027114557,0.0003415651,0.000028838875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004520025,0.000036079746,0.008985692,0.0001248052,0.00010960348,0.000012204758,0.000601027,0.000040803883,0.9828871,0.00003343849,0.005979956,0.0007372697],"study_design_scores_gemma":[0.0038242377,0.00062642334,0.01428966,0.000029298119,0.00001830988,0.000010451146,0.00065198255,0.0016574094,0.95916706,0.000020053609,0.019389942,0.00031518505],"about_ca_topic_score_codex":0.000043956996,"about_ca_topic_score_gemma":0.0000201007,"teacher_disagreement_score":0.02372007,"about_ca_system_score_codex":0.00003420571,"about_ca_system_score_gemma":0.00005856587,"threshold_uncertainty_score":0.8439094},"labels":[],"label_agreement":null},{"id":"W3036308450","doi":"10.1139/cjm-2020-0212","title":"A short overview of the CRISPR-Cas adaptation stage","year":2020,"lang":"en","type":"review","venue":"Canadian Journal of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Biology; Adaptation (eye); Streptococcus thermophilus; Computational biology; Function (biology); Genome editing; Genome; Genetics; Bacteria; Gene","score_opus":0.04403859921477753,"score_gpt":0.33261186777075613,"score_spread":0.2885732685559786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036308450","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017197093,0.99772686,0.0009771674,0.000054252185,0.0005943176,0.00017209344,0.0002449984,7.909047e-7,0.000057534246],"genre_scores_gemma":[0.0038699305,0.99539083,0.0001694805,0.00008479548,0.00025908506,0.0000024953022,0.00006679262,0.000030572028,0.00012599885],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988895,0.0001306786,0.00057392905,0.00016225984,0.000032209547,0.00021140484],"domain_scores_gemma":[0.99912167,0.000016112901,0.00031793377,0.0002482891,0.00010935619,0.00018665363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016539345,0.00020939657,0.0007228201,0.000098342636,0.000035375357,0.000008351385,0.0004800277,0.00031099128,0.000033460878],"category_scores_gemma":[0.000106787775,0.00014939006,0.000527883,0.00012738231,0.0000934304,0.0000013605271,0.00004418988,0.00028595695,0.0000030213703],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011819395,0.000013924602,0.000055345477,0.0051468113,0.00086225785,0.00008593071,0.00021604804,0.00017793053,0.015456966,0.00007680211,0.0103479,0.96754825],"study_design_scores_gemma":[0.00007217767,0.0001058163,0.000013004998,0.00093440915,0.00023112784,0.0006177869,0.000028153865,9.229187e-7,0.0014011506,0.0000018542432,0.99645895,0.00013464995],"about_ca_topic_score_codex":0.00015147756,"about_ca_topic_score_gemma":0.0037206467,"teacher_disagreement_score":0.98611104,"about_ca_system_score_codex":0.000052915006,"about_ca_system_score_gemma":0.0018112038,"threshold_uncertainty_score":0.60919505},"labels":[],"label_agreement":null},{"id":"W3036325859","doi":"10.1101/2020.06.22.165571","title":"High-throughput binding affinity measurements for mutations spanning a transcription factor-DNA interface reveal affinity and specificity determinants","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Chemistry, Engineering and Medicine for Human Health, Stanford University; Alfred P. Sloan Foundation; National Science Foundation","keywords":"Transcription factor; DNA; Biology; Genetics; Mutant; Gene; Oligonucleotide; DNA binding site; Binding site; DNA sequencing; DNA-binding protein; Mutation; Computational biology; Promoter; Gene expression","score_opus":0.04182744343202348,"score_gpt":0.2905888410853286,"score_spread":0.24876139765330513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036325859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93030053,0.0007496743,0.066126324,0.000089986796,0.00096469163,0.00085585786,0.0008032479,0.00010784014,0.0000018202402],"genre_scores_gemma":[0.98450315,0.00017313528,0.014473654,0.000037543858,0.0005333211,0.00015188658,0.0000065800627,0.0001174107,0.000003321888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99749506,0.00009226252,0.0005350056,0.0011299684,0.00025329358,0.00049442425],"domain_scores_gemma":[0.99854374,0.00003049335,0.00027574916,0.00060838024,0.0002778262,0.00026378283],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035851938,0.00056288205,0.0005198319,0.00011948343,0.00022742631,0.00017570937,0.0003396961,0.0005115442,0.000007550122],"category_scores_gemma":[0.0002737497,0.00066815846,0.00017972065,0.00016085453,0.00008760369,0.000017744758,0.00031120097,0.00042255726,0.0000056053996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007884432,0.000059951122,0.0024326476,0.00045728087,0.00014384209,0.000004280154,0.000033696288,0.00032931007,0.99635464,0.000009667528,0.00008221303,0.0000136178],"study_design_scores_gemma":[0.00072312256,0.00013236857,0.03886052,0.00022574817,0.00013035972,5.7078925e-8,0.000014508999,0.00022418094,0.9583697,0.0000025472411,0.0006495467,0.00066739094],"about_ca_topic_score_codex":0.00002810506,"about_ca_topic_score_gemma":0.000016196302,"teacher_disagreement_score":0.05420259,"about_ca_system_score_codex":0.00010642636,"about_ca_system_score_gemma":0.00020197507,"threshold_uncertainty_score":0.999577},"labels":[],"label_agreement":null},{"id":"W3036334275","doi":"10.17912/micropub.biology.000075","title":"Expression pattern of endogenous PAR-4A &amp; C after CRISPR/Cas9-mediated genome editing","year":2018,"lang":"en","type":"article","venue":"PubMed","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université du Québec à Trois-Rivières; Université Laval","funders":"National Institutes of Health","keywords":"CRISPR; Genome editing; Biology; Endogeny; Genome; Computational biology; Genetics; Cas9; Gene; Biochemistry","score_opus":0.015137200069961403,"score_gpt":0.24334715858347886,"score_spread":0.22820995851351744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036334275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98312694,0.0010047634,0.014279445,0.000035156318,0.00038617075,0.00029536415,0.000050336483,0.000022289802,0.00079951924],"genre_scores_gemma":[0.9977286,0.000055827306,0.00032192058,0.000120360215,0.001184514,0.0003443714,0.00009836379,0.000030206009,0.00011585727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894845,0.000026036096,0.00023356966,0.00027994247,0.00012857509,0.00038340097],"domain_scores_gemma":[0.99936783,0.000010768947,0.000071777606,0.00034581302,0.00008601552,0.00011779031],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001614261,0.00014579881,0.00014479275,0.00004550656,0.000040956016,0.000012816422,0.0001522004,0.00012135976,0.00005053068],"category_scores_gemma":[0.00009298464,0.00013842683,0.00007301289,0.00006626048,0.00006958126,0.0000029966825,0.00013113335,0.00006436271,0.000017309972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041440726,0.00003605335,0.0063429973,0.00003844337,0.000030980813,0.000003669592,0.0001745,0.00001780124,0.98127913,1.5506953e-7,0.00048241223,0.011552423],"study_design_scores_gemma":[0.00034104378,0.000050039627,0.08203403,0.000009110864,0.000016063512,0.000015493626,0.000030673218,0.000009157082,0.88965464,0.000004037307,0.027656445,0.00017929454],"about_ca_topic_score_codex":0.000016930591,"about_ca_topic_score_gemma":0.00003313114,"teacher_disagreement_score":0.091624506,"about_ca_system_score_codex":0.000008605777,"about_ca_system_score_gemma":0.000011581515,"threshold_uncertainty_score":0.5644882},"labels":[],"label_agreement":null},{"id":"W3036667822","doi":"10.1007/s40778-020-00173-3","title":"In Vivo Genome Engineering for the Treatment of Muscular Dystrophies","year":2020,"lang":"en","type":"article","venue":"Current Stem Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"CRISPR; Cas9; Genome editing; Muscular dystrophy; Biology; Genetic enhancement; Phenotype; Computational biology; Muscle disorder; Gene; Genetics; Bioinformatics; Medicine; Internal medicine","score_opus":0.013705322175962847,"score_gpt":0.2678671630534543,"score_spread":0.2541618408774915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036667822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94341546,0.026398677,0.029043753,0.000074109674,0.0005024114,0.0005080267,0.000012821435,0.000009081971,0.00003567708],"genre_scores_gemma":[0.99814117,0.0013300161,0.00015091545,0.000006737514,0.0002164596,0.00006645133,0.000012095848,0.000015377609,0.000060803413],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937445,0.000004338562,0.00022854301,0.00019853293,0.0000614027,0.00013271296],"domain_scores_gemma":[0.9996589,0.000010101385,0.000060169637,0.00020446476,0.000021417718,0.000044965385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004381134,0.00010961272,0.00012873688,0.00001866762,0.000015789576,0.000005435953,0.000053935182,0.000034398116,0.000005366094],"category_scores_gemma":[0.000006239988,0.00008327202,0.00011075103,0.00005296094,0.000010630124,0.0000012578898,0.000019417312,0.000022930626,3.1378357e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001712212,0.00007419196,0.0005831118,0.00020541971,0.00003515335,0.000016220622,0.00033529405,0.03709998,0.9595026,0.0000046071773,0.00016954458,0.0019568002],"study_design_scores_gemma":[0.00025908617,0.0002559764,0.0003837464,0.000008363418,0.000027964697,0.000008551755,0.000051502153,0.0014009427,0.6488116,0.0000012322712,0.34868488,0.00010615382],"about_ca_topic_score_codex":0.0000024683538,"about_ca_topic_score_gemma":0.0000010395946,"teacher_disagreement_score":0.34851533,"about_ca_system_score_codex":0.0000104602295,"about_ca_system_score_gemma":0.000017278695,"threshold_uncertainty_score":0.33957344},"labels":[],"label_agreement":null},{"id":"W3037032230","doi":"10.1007/s11427-020-1722-0","title":"Shortening the sgRNA-DNA interface enables SpCas9 and eSpCas9(1.1) to nick the target DNA strand","year":2020,"lang":"en","type":"article","venue":"Science China Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Cas9; Cleavage (geology); DNA; Genome editing; Guide RNA; Biology; CRISPR; Plasmid; Computational biology; Genetics; Gene","score_opus":0.013355823710169473,"score_gpt":0.30313549758281094,"score_spread":0.2897796738726415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037032230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9768531,0.0019413306,0.010470025,0.009304983,0.00024538705,0.0002133124,0.0000057170696,0.000016216693,0.0009499841],"genre_scores_gemma":[0.99666816,0.00008822527,0.001631773,0.001319059,0.00021272099,0.000007501576,7.75164e-7,0.0000065552163,0.000065225984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842185,0.000033299053,0.00016621283,0.00056745525,0.000391417,0.00041979377],"domain_scores_gemma":[0.99937636,0.000027005637,0.00004089375,0.00025227535,0.00003964317,0.0002638484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001107708,0.00015191906,0.0001095082,0.000038958384,0.0008493983,0.000269717,0.0011231139,0.00003273927,0.000014111551],"category_scores_gemma":[0.00045854124,0.00008293303,0.000040023155,0.00070256914,0.0013383471,0.000024469604,0.00043539773,0.000106335996,0.000007182507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014926214,0.000007945655,0.0019073752,0.000009521135,0.000008920242,0.000001084355,0.0024421709,0.009858996,0.9821103,0.00017350068,0.001468658,0.001996579],"study_design_scores_gemma":[0.00025942968,0.00081995345,0.02009594,0.000034171484,0.000022005117,0.000043010186,0.006330364,0.016245632,0.92289555,0.0002702936,0.032479808,0.00050382904],"about_ca_topic_score_codex":0.000018251942,"about_ca_topic_score_gemma":0.00001689866,"teacher_disagreement_score":0.05921476,"about_ca_system_score_codex":0.0000056653007,"about_ca_system_score_gemma":0.00019355818,"threshold_uncertainty_score":0.6532971},"labels":[],"label_agreement":null},{"id":"W3037131049","doi":"10.1007/s43152-020-00011-y","title":"CRISPR/Cas9 in Male Factor Infertility","year":2020,"lang":"en","type":"article","venue":"Current Tissue Microenvironment Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Cas9; Genome editing; Male infertility; Infertility; Biology; Genetics; Reproductive technology; Computational biology; Gene; Bioinformatics; Pregnancy","score_opus":0.015520765564334314,"score_gpt":0.3003938633152295,"score_spread":0.2848730977508952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037131049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98173994,0.009131071,0.008177813,0.00020845413,0.0002882951,0.00029721097,0.000013319068,0.000015115383,0.0001287701],"genre_scores_gemma":[0.9987218,0.0004747319,0.00021406797,0.00008795793,0.00016589335,0.000023285262,0.00010372602,0.000021742524,0.00018682073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987127,0.000022363514,0.00035309704,0.0005122105,0.00012834968,0.00027123548],"domain_scores_gemma":[0.9994137,0.0000027966391,0.00007331901,0.00034903572,0.0000066474263,0.00015445924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000620874,0.00019167749,0.00016696028,0.000023097842,0.000025927271,0.000014957368,0.00009650778,0.00007593192,0.0002737122],"category_scores_gemma":[0.000041524912,0.00020398025,0.00006186594,0.00005332838,0.00003855292,0.0000037097982,0.00016502524,0.00012692132,0.00003358208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013330473,0.0000919967,0.13478202,0.000058479123,0.000009864824,0.000090748545,0.00012540496,0.00042639032,0.8514554,7.0807744e-7,0.0019289764,0.011016667],"study_design_scores_gemma":[0.00017503671,0.000077533914,0.104790114,0.000012062382,0.0000071906165,0.00005572173,0.000015891512,0.000020282812,0.48471013,0.0000032638543,0.4099346,0.00019816126],"about_ca_topic_score_codex":0.000006937485,"about_ca_topic_score_gemma":0.000006642837,"teacher_disagreement_score":0.40800563,"about_ca_system_score_codex":0.000027880109,"about_ca_system_score_gemma":0.000017153721,"threshold_uncertainty_score":0.8318073},"labels":[],"label_agreement":null},{"id":"W3037267465","doi":"10.1089/hum.2020.111","title":"CRISPR/Cas9 Editing: Sparking Discussion on Safety in Light of the Need for New Therapeutics","year":2020,"lang":"en","type":"review","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Genome editing; CRISPR; Cas9; Computational biology; Function (biology); Biology; Genome; Transcription activator-like effector nuclease; Genetics; Gene","score_opus":0.052652724123165205,"score_gpt":0.3753935562712434,"score_spread":0.3227408321480782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037267465","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017457368,0.9959114,0.0017362152,0.00033004285,0.00042991427,0.0010758684,0.000032361302,0.000012291143,0.00029729237],"genre_scores_gemma":[0.0010822562,0.99593973,0.0002667051,0.00019306185,0.0016150523,0.00005211307,0.00013552635,0.00010762638,0.000607952],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985674,0.00008782176,0.00051781186,0.00041769596,0.00014834318,0.0002608961],"domain_scores_gemma":[0.9990864,0.000022051669,0.00024394497,0.0005607439,0.00002612603,0.0000607708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016384032,0.00038188093,0.00070689723,0.00006466243,0.00010162029,0.000023478668,0.00047487122,0.00028841948,0.000011751148],"category_scores_gemma":[0.000015354053,0.00021628897,0.00045450835,0.00015003164,0.000033198176,0.0000013308041,0.00009092903,0.00022081193,0.0000014457456],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008019866,0.000061798055,0.000006532464,0.00086119503,0.00021125657,0.0000013811322,0.00027011105,0.00008525027,0.048494868,0.00008971996,0.0012306204,0.9486071],"study_design_scores_gemma":[0.00058208854,0.00031349403,0.000013432015,0.0010019848,0.000075684664,0.0000043849573,0.000018297747,0.0000073372225,0.035647932,0.00004974197,0.96202785,0.00025774445],"about_ca_topic_score_codex":0.0000045432735,"about_ca_topic_score_gemma":0.000015893325,"teacher_disagreement_score":0.96079725,"about_ca_system_score_codex":0.000029554558,"about_ca_system_score_gemma":0.00015410465,"threshold_uncertainty_score":0.8820008},"labels":[],"label_agreement":null},{"id":"W3037380067","doi":"10.1128/msphere.00235-20","title":"Characterization of a Type II-A CRISPR-Cas System in <i>Streptococcus mutans</i>","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"University of Toronto; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"CRISPR; Streptococcus mutans; Biology; Genome editing; Computational biology; Adaptation (eye); Bacteria; Microbiology; Genetics; Gene","score_opus":0.007599037939071524,"score_gpt":0.2518717941244097,"score_spread":0.24427275618533817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037380067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934591,0.00024766152,0.0050208555,0.000074902826,0.00008747077,0.00014091977,0.000014107595,0.000014937308,0.0009400108],"genre_scores_gemma":[0.99950033,0.000027686177,0.00011972333,0.0000811553,0.000108800225,0.000008053144,0.00006730273,0.000014030965,0.0000728985],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951273,0.0000120894565,0.00015604691,0.00016036135,0.000055457618,0.00010328579],"domain_scores_gemma":[0.9997474,0.0000016626536,0.00003588882,0.00012854,0.0000428819,0.000043626158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000030002542,0.00008011326,0.00010792244,0.000008558384,0.000014096349,0.0000045240736,0.00008050515,0.000074335556,0.00003363653],"category_scores_gemma":[0.000021743157,0.00008272458,0.000027941887,0.00014191911,0.000010307212,0.000001650287,0.000050471404,0.000042145442,0.0000059847266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028079668,0.000012663035,0.0036074584,0.000100285375,0.000009410053,0.0000033832373,0.00015398928,0.00030503355,0.99473274,0.000016629554,0.00014952994,0.0008808022],"study_design_scores_gemma":[0.0003067995,0.00019343375,0.0057797167,0.000033135897,0.000007639253,0.0000029533046,0.00016779001,0.0008814951,0.97835445,5.940356e-7,0.014162649,0.000109352324],"about_ca_topic_score_codex":0.000007995312,"about_ca_topic_score_gemma":0.000011514495,"teacher_disagreement_score":0.016378295,"about_ca_system_score_codex":0.00000666381,"about_ca_system_score_gemma":0.000024592551,"threshold_uncertainty_score":0.33734107},"labels":[],"label_agreement":null},{"id":"W3037440291","doi":"10.1038/s41587-020-0566-4","title":"Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC–Cas9","year":2020,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"APOBEC; Cas9; Biology; CRISPR; Genetics; Genome; AP site; DNA; Computational biology; Gene; DNA repair","score_opus":0.009407028318228263,"score_gpt":0.28502482720234756,"score_spread":0.2756177988841193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037440291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9623641,0.009260259,0.025932305,0.0018832051,0.0001302841,0.00021789283,0.000022966859,0.000072933595,0.00011604727],"genre_scores_gemma":[0.9838757,0.0007169554,0.014876788,0.0003371269,0.000100691075,0.0000075620183,0.00002043936,0.000022271768,0.00004244777],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913454,0.00001578084,0.0001498806,0.0003960662,0.00005749295,0.00024625415],"domain_scores_gemma":[0.99965435,0.000007647266,0.000028498023,0.00021286894,0.000025866939,0.00007077222],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000581786,0.00014345837,0.00014903638,0.00008353383,0.00004408481,0.00001083626,0.00015801484,0.00092511706,0.0000056148688],"category_scores_gemma":[0.00016834773,0.00014950465,0.00003234485,0.0002300062,0.000072014045,0.000003420211,0.00018295659,0.00048439353,0.0000024077365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002194854,0.00002314852,0.0014500595,0.000025119321,0.000015716041,0.000007386706,0.000025676269,0.0005696147,0.99623644,0.000083395425,0.00037691786,0.0011645738],"study_design_scores_gemma":[0.0009454341,0.00018962673,0.0029495594,0.000022822966,0.000018455019,0.00006009292,0.000091421425,0.01248994,0.9301629,0.000025539743,0.05275943,0.00028477775],"about_ca_topic_score_codex":0.000021989203,"about_ca_topic_score_gemma":0.00007504731,"teacher_disagreement_score":0.066073544,"about_ca_system_score_codex":0.000012143667,"about_ca_system_score_gemma":0.000022400694,"threshold_uncertainty_score":0.713535},"labels":[],"label_agreement":null},{"id":"W3038097601","doi":"10.1016/j.mrrev.2020.108318","title":"Reprint of: Deciphering and simulating models of radiation genotoxicity with CRISPR/Cas9 systems","year":2020,"lang":"en","type":"article","venue":"Mutation Research/Reviews in Mutation Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"CANDU Owners Group; Bruce Power","keywords":"CRISPR; Cas9; Radiobiology; Context (archaeology); Computational biology; Biology; Mitophagy; DNA; Computer science; Genetics; Physics; Gene","score_opus":0.14325391275267577,"score_gpt":0.4585285043014394,"score_spread":0.3152745915487636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3038097601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.847235,0.007557682,0.14345253,0.00014148756,0.000017728837,0.0013092926,0.0000073637984,0.00000709706,0.00027182765],"genre_scores_gemma":[0.9937175,0.0022167787,0.0037673935,0.000012907412,0.00006146352,0.0001393602,0.00003903674,0.000023784052,0.000021780537],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99714804,0.00074842054,0.000640328,0.00043814993,0.00069630507,0.0003287388],"domain_scores_gemma":[0.9985588,0.00025479085,0.00013821214,0.0002721519,0.0006471084,0.00012888826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004205481,0.00012246607,0.00028407553,0.00022776349,0.00009260662,0.00004116945,0.00017781253,0.00010242779,0.000009102748],"category_scores_gemma":[0.00154924,0.00011447191,0.000046849003,0.00083985104,0.00016935951,0.000022819451,0.00014556538,0.000323244,0.0000027376345],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001908662,0.000053282813,0.002778309,0.001539435,0.00003467837,0.000010300808,0.0030132043,0.70098597,0.24563003,0.00036168247,0.00008039125,0.04532187],"study_design_scores_gemma":[0.0012509458,0.00083787,0.0050039697,0.0004357143,0.000009556846,0.000011777452,0.0030513003,0.73354495,0.25414112,0.00027438274,0.001205314,0.00023307385],"about_ca_topic_score_codex":0.00020515604,"about_ca_topic_score_gemma":0.00003985499,"teacher_disagreement_score":0.1464825,"about_ca_system_score_codex":0.00004350715,"about_ca_system_score_gemma":0.00013476191,"threshold_uncertainty_score":0.46680292},"labels":[],"label_agreement":null},{"id":"W3039215027","doi":"10.1007/s00439-020-02201-y","title":"Interplay between probe design and test performance: overlap between genomic regions of interest, capture regions and high quality reference calls influence performance of WES-based assays","year":2020,"lang":"en","type":"article","venue":"Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Newborn Screening Ontario; University of Ottawa; Canadian Association of Physicists; Agricultural Research Institute of Ontario","funders":"","keywords":"Biology; Exome; Computational biology; Exome sequencing; International HapMap Project; Sample size determination; Genomics; Genetics; Genome; Human genome; Gene; Statistics; Mathematics; Phenotype","score_opus":0.06168532258452457,"score_gpt":0.33038194664096604,"score_spread":0.26869662405644146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3039215027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98350316,0.00059868157,0.015400279,0.000085452804,0.000012833083,0.0002787498,0.000080737496,0.000012768099,0.000027329495],"genre_scores_gemma":[0.9953423,0.00042695802,0.003939866,0.0000560553,0.00008367985,0.000010880236,0.000081456295,0.000027419463,0.00003137703],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998747,0.00006323048,0.00047555257,0.00037639428,0.00011334277,0.00022448457],"domain_scores_gemma":[0.9990696,0.0000885501,0.00020314749,0.00036505348,0.00011948016,0.00015420884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019965558,0.0002285828,0.00033829772,0.000044255445,0.000078685225,0.000016332599,0.00025839402,0.00019319949,0.0000029523385],"category_scores_gemma":[0.00008337777,0.00022975633,0.00004340961,0.00009174589,0.00025760528,0.000006783525,0.00019564401,0.00019796449,6.85952e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037671598,0.000021673213,0.41327918,0.0004479339,0.000047899248,4.8760865e-7,0.00026922522,0.0020248294,0.58309543,0.000048355392,0.00008816584,0.00063916674],"study_design_scores_gemma":[0.00056692114,0.0013274472,0.62339693,0.00014424452,0.00008353524,0.000002685882,0.000050155053,0.00078548986,0.37297952,0.000029608416,0.00033929572,0.0002941835],"about_ca_topic_score_codex":0.000028786078,"about_ca_topic_score_gemma":0.000012635404,"teacher_disagreement_score":0.21011774,"about_ca_system_score_codex":0.000011615875,"about_ca_system_score_gemma":0.000079253834,"threshold_uncertainty_score":0.93691915},"labels":[],"label_agreement":null},{"id":"W3041085494","doi":"10.1038/s41467-020-17061-3","title":"Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Directorate for Biological Sciences; Horizon 2020 Framework Programme; University of Cambridge; Research Councils UK; Dell EMC","keywords":"Mutagenesis; INDEL Mutation; Genetics; Indel; Biology; Sequence space; Point mutation; Computational biology; Directed evolution; Triad (sociology); Mutation; Gene; Mutant","score_opus":0.02847221094506957,"score_gpt":0.3304540784379918,"score_spread":0.3019818674929222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041085494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82453585,0.02110075,0.14236777,0.010625423,0.00014018375,0.00043555215,0.000038617352,0.00011861499,0.0006372449],"genre_scores_gemma":[0.9912751,0.0007356734,0.007542756,0.0001315766,0.000041467756,0.000024603449,0.00022147708,0.00001401811,0.000013368192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934894,0.00008472514,0.00019865455,0.00017407858,0.00008339585,0.00011020639],"domain_scores_gemma":[0.999086,0.000024299068,0.000075753094,0.0006499308,0.00011451524,0.000049474827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080545855,0.00009261329,0.00010504937,0.00006103823,0.00007425647,0.000009215058,0.00041727314,0.00020860412,0.0000026939126],"category_scores_gemma":[0.00021483892,0.00010307555,0.000050054205,0.00043180416,0.00006482843,0.000008678433,0.00016985154,0.00025238207,0.0000015682342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018022925,0.00003889674,0.0026964778,0.000015178339,0.000013723285,3.1019383e-7,0.00016443427,0.0018530891,0.99381346,0.00049636094,0.00030958364,0.00058048905],"study_design_scores_gemma":[0.000988141,0.00016557827,0.12765886,0.00012442922,0.00006923507,0.000013701505,0.00044890246,0.057602584,0.78707576,0.00030496946,0.0249941,0.00055374776],"about_ca_topic_score_codex":0.00004881803,"about_ca_topic_score_gemma":0.0003370964,"teacher_disagreement_score":0.20673768,"about_ca_system_score_codex":0.000028099585,"about_ca_system_score_gemma":0.00005127102,"threshold_uncertainty_score":0.4203299},"labels":[],"label_agreement":null},{"id":"W3041642684","doi":"10.3390/su12145651","title":"Impact of the SARS-CoV-2 on the Italian Agri-Food Sector: An Analysis of the Quarter of Pandemic Lockdown and Clues for a Socio-Economic and Territorial Restart","year":2020,"lang":"en","type":"article","venue":"Sustainability","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Agriculture; Tourism; Quarter (Canadian coin); Sustainability; Pandemic; Geography; Economic sector; Economic growth; Business; Economy; Economics; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty); Ecology","score_opus":0.01322263746059963,"score_gpt":0.3145811967286825,"score_spread":0.30135855926808286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041642684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987806,0.00008268927,0.00010122899,0.0004880736,0.000048860715,0.00034228456,0.00014827098,0.0000021200258,0.0000058808823],"genre_scores_gemma":[0.99984324,0.000005689628,0.0000081850785,0.000025837879,0.000093506365,0.000009124513,0.0000062600625,0.0000057722673,0.0000023737678],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993727,0.000082732266,0.00019023904,0.00019064485,0.00005414714,0.00010953985],"domain_scores_gemma":[0.9994014,0.00004732706,0.00008718014,0.00035822994,0.000085260974,0.000020638436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021987986,0.000094369694,0.00018246405,0.000014668839,0.00004455198,0.0000069179755,0.00014891791,0.000073523435,0.0000017501189],"category_scores_gemma":[0.00018702672,0.000049931798,0.00021995312,0.00006677699,0.00021818766,0.0000028096208,0.00007532058,0.000053702803,8.290042e-9],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047051167,0.00007434696,0.54614425,0.00022912178,0.0008064718,5.4902607e-8,0.0035138866,0.0019022013,0.4459121,0.00019798626,0.00037207938,0.00037701556],"study_design_scores_gemma":[0.00064787536,0.0017542791,0.75676966,0.00000783412,0.00037723,7.416671e-7,0.0030970776,0.0019184784,0.23364055,0.0013501347,0.00028340815,0.00015272193],"about_ca_topic_score_codex":0.00023947004,"about_ca_topic_score_gemma":0.00034155214,"teacher_disagreement_score":0.21227154,"about_ca_system_score_codex":0.000040587685,"about_ca_system_score_gemma":0.00011486601,"threshold_uncertainty_score":0.20361596},"labels":[],"label_agreement":null},{"id":"W3041710921","doi":"10.1101/2020.07.09.193847","title":"Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; University of Waterloo; Searle Scholars Program; Damon Runyon Cancer Research Foundation; University of California, San Francisco; Burroughs Wellcome Fund","keywords":"CRISPR; Cas9; Biology; Microbiome; Bacteriophage; Computational biology; Trans-activating crRNA; Escherichia coli; Genetics; Gene; Strain (injury)","score_opus":0.014686054227018106,"score_gpt":0.2504410970460211,"score_spread":0.23575504281900297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041710921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92240286,0.007400189,0.06692223,0.00055031467,0.00043290763,0.0012756523,0.00095378055,0.00005799374,0.0000040996765],"genre_scores_gemma":[0.9894054,0.0014922529,0.007857139,0.00029747907,0.0005694663,0.0002725463,0.0000122563315,0.0000913853,0.000002075141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981756,0.00007779552,0.00038168166,0.00084915635,0.00011913318,0.00039659452],"domain_scores_gemma":[0.9988861,0.000026848076,0.00013065712,0.00070293824,0.00013574288,0.00011773092],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003550776,0.0003971017,0.00030376538,0.00011276487,0.00012424386,0.0001478367,0.00044279313,0.0004002573,0.000007498051],"category_scores_gemma":[0.000062482664,0.00040048678,0.00012471403,0.00016576481,0.000084966574,0.000005030373,0.00028205058,0.00034680465,0.0000070916667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035633777,0.000042601987,0.00024693325,0.00017952749,0.00006127755,0.000008573604,0.000021105316,0.00024813015,0.99797785,0.00014409117,0.001028041,0.0000062384775],"study_design_scores_gemma":[0.002530278,0.00035095567,0.13174883,0.00020415269,0.00020778406,4.5001863e-7,0.000059020567,0.0012745332,0.72440296,0.000012621835,0.13750768,0.0017007351],"about_ca_topic_score_codex":0.000013560198,"about_ca_topic_score_gemma":0.000008176301,"teacher_disagreement_score":0.2735749,"about_ca_system_score_codex":0.00005666357,"about_ca_system_score_gemma":0.00013629576,"threshold_uncertainty_score":0.99984473},"labels":[],"label_agreement":null},{"id":"W3041946983","doi":"10.1016/j.molbiopara.2020.111295","title":"Bar-seq strategies for the LeishGEdit toolbox","year":2020,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council Canada; Royal Society","keywords":"CRISPR; Biology; Computational biology; Genome; Pipeline (software); Barcode; Function (biology); Genome editing; Genetics; Gene; Computer science; Programming language","score_opus":0.010571905311159372,"score_gpt":0.3092427184433535,"score_spread":0.2986708131321941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041946983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7108345,0.005562146,0.27874073,0.004091975,0.00013751902,0.0002642246,0.000016767413,0.000022196427,0.0003299158],"genre_scores_gemma":[0.99644744,0.00007052101,0.0011896329,0.0018243656,0.00033178247,0.000044732238,0.00005307361,0.000017855904,0.000020585305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919325,0.000018604052,0.00014150143,0.00034025148,0.00006357745,0.00024283127],"domain_scores_gemma":[0.9996139,0.00003125517,0.000032415195,0.00017823726,0.000036122718,0.00010806741],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054617878,0.00015424196,0.0001450845,0.000009320886,0.00006694315,0.00003294127,0.0001801741,0.0001701648,0.000008362114],"category_scores_gemma":[0.000095473486,0.000118363954,0.0000950056,0.000047946527,0.00013666814,0.0000020183847,0.00006973978,0.000095572264,0.000003622037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008069857,0.000010140621,0.00030713802,0.000026642725,0.000058727008,0.0000038699786,0.00003492032,0.00014116654,0.9917712,0.00075766566,0.0061539966,0.0006538127],"study_design_scores_gemma":[0.0005512604,0.00031041022,0.0006805857,0.0000030001377,0.00005597418,0.000037207967,0.0001730496,0.00078445725,0.9645688,0.00033558084,0.03226958,0.00023007377],"about_ca_topic_score_codex":0.0000039337733,"about_ca_topic_score_gemma":0.0000015019871,"teacher_disagreement_score":0.28561294,"about_ca_system_score_codex":0.0000023872133,"about_ca_system_score_gemma":0.000031732667,"threshold_uncertainty_score":0.4826742},"labels":[],"label_agreement":null},{"id":"W3041967090","doi":"10.1007/s12551-020-00717-1","title":"Synthetic biology approaches to dissecting linear motor protein function: towards the design and synthesis of artificial autonomous protein walkers","year":2020,"lang":"en","type":"review","venue":"Biophysical Reviews","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Vetenskapsrådet; Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse; European Commission","keywords":"Membrane biology; Synthetic biology; Function (biology); Protein design; Biological system; Computer science; Biophysics; Biology; Computational biology; Cell biology; Biochemistry; Protein structure; Membrane","score_opus":0.11938112764866791,"score_gpt":0.33027609079481873,"score_spread":0.2108949631461508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041967090","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015116429,0.94193316,0.0531716,0.00011358297,0.0001021953,0.004447816,0.00003175073,0.000018089613,0.000030664713],"genre_scores_gemma":[0.0026700732,0.9821926,0.010097024,0.000030019544,0.0013433492,0.0034007977,0.000038942308,0.00010668862,0.000120511795],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99771184,0.0004656827,0.00072155014,0.00071173045,0.0001031033,0.00028610197],"domain_scores_gemma":[0.99892074,0.00007365687,0.00027949444,0.00054436486,0.00003315467,0.00014858833],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005163125,0.00047993247,0.001416405,0.00004669643,0.00007900621,0.000024382287,0.0003490907,0.00027492997,0.0000066780117],"category_scores_gemma":[0.0010207037,0.0002999957,0.00052758545,0.00024285702,0.00013057608,0.0000022074646,0.0002201001,0.00023671146,0.000028965473],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028202274,0.000045377517,3.307875e-8,0.004511793,0.00009797328,6.94974e-7,0.000014888053,0.0000055481173,0.03663355,0.00014199271,0.000028696415,0.95849127],"study_design_scores_gemma":[0.000035850102,0.00052750745,5.2816404e-7,0.002545534,0.00042853653,0.000005572117,0.000009393223,0.00017752487,0.022684181,0.00002744335,0.97317743,0.00038051567],"about_ca_topic_score_codex":0.0000065299164,"about_ca_topic_score_gemma":7.603381e-7,"teacher_disagreement_score":0.9731487,"about_ca_system_score_codex":0.000021903683,"about_ca_system_score_gemma":0.00014128485,"threshold_uncertainty_score":0.9999452},"labels":[],"label_agreement":null},{"id":"W3041990254","doi":"10.1111/pbi.13444","title":"Base editing with high efficiency in allotetraploid oilseed rape by A3A‐PBE system","year":2020,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Chinese Academy of Agricultural Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Biology; Base (topology); Biotechnology; Evolutionary biology","score_opus":0.004291740902250741,"score_gpt":0.2024120064222227,"score_spread":0.19812026551997197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041990254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9540136,0.0020367284,0.04074015,0.002646682,0.00022211783,0.00011809556,0.000056177636,0.000080926024,0.000085518026],"genre_scores_gemma":[0.99749005,0.00043572672,0.001529661,0.00018564524,0.00027146674,0.0000051629977,0.000048242742,0.000024802734,0.000009267468],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988378,0.00003077076,0.00028545444,0.00031833237,0.000138195,0.0003894094],"domain_scores_gemma":[0.9995632,0.000011432428,0.000101537335,0.00016022795,0.00002849545,0.00013510066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017238877,0.00019297095,0.00021283446,0.000118942946,0.0000877588,0.000027581991,0.00029466068,0.0003411578,0.00000814907],"category_scores_gemma":[0.000066155,0.00016371696,0.00004586225,0.0002239436,0.000068023954,0.0000040089485,0.00007147375,0.0005176899,0.0000059904473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105737745,0.00003668722,0.0010173304,0.00004168323,0.000046021447,0.00022623889,0.000044886256,0.0011220945,0.99495995,0.000052377523,0.0011003364,0.0012466584],"study_design_scores_gemma":[0.0014867126,0.00081539754,0.00021983209,0.00009180617,0.000023911884,0.001990947,0.0006081134,0.002284281,0.98174137,0.0000026450566,0.01042838,0.00030661604],"about_ca_topic_score_codex":0.000012826369,"about_ca_topic_score_gemma":0.00001431862,"teacher_disagreement_score":0.04347642,"about_ca_system_score_codex":0.00002344236,"about_ca_system_score_gemma":0.000046777695,"threshold_uncertainty_score":0.6676184},"labels":[],"label_agreement":null},{"id":"W3042200502","doi":"10.15625/1811-4989/16/1/10629","title":"Current status of genetic engineering in the fields of medicine, pharmacology and agriculture in China, Japan and Korea","year":2018,"lang":"en","type":"article","venue":"Vietnam Journal of Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biotechnology; Agriculture; China; Underdevelopment; Translational medicine; Economic growth; Political science; Business; Biology; Genetics; Ecology","score_opus":0.0041726924859606055,"score_gpt":0.2714900219112512,"score_spread":0.26731732942529063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042200502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97933257,0.0185282,0.0012482528,0.0006698841,0.00012843024,0.000072979914,0.0000017581546,0.0000012350438,0.000016691694],"genre_scores_gemma":[0.9880664,0.01137514,0.00041813083,0.000022417338,0.00011003654,0.0000015222362,0.0000011560015,0.00000429409,9.2653033e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933493,0.000024596522,0.00032301646,0.000098575416,0.000059796337,0.00015909919],"domain_scores_gemma":[0.9997052,0.000013885117,0.00012355445,0.00009171069,0.000035852267,0.00002982935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017239085,0.00008887286,0.00020539164,0.00017439859,0.000009065168,0.0000014338353,0.00013518172,0.00018326919,0.0000045136117],"category_scores_gemma":[0.00006875831,0.000058731526,0.000023317907,0.00016037312,0.0002052812,0.000002127436,0.000054257507,0.0002228679,3.5465778e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004027218,0.00003947837,0.008590702,0.00006816792,0.000025548792,0.0000045126867,0.0004979388,0.0002573789,0.9712391,0.0000689547,0.00027864595,0.018889334],"study_design_scores_gemma":[0.0024599668,0.0030614845,0.21958971,0.00016663857,0.00005546126,0.00045975886,0.00060639705,0.0005781825,0.76554066,0.00011672905,0.007205523,0.00015946341],"about_ca_topic_score_codex":0.000019674408,"about_ca_topic_score_gemma":0.00005015194,"teacher_disagreement_score":0.21099901,"about_ca_system_score_codex":0.0000045416255,"about_ca_system_score_gemma":0.000017605005,"threshold_uncertainty_score":0.23950021},"labels":[],"label_agreement":null},{"id":"W3042463377","doi":"10.1016/j.ydbio.2020.07.007","title":"An optimized QF-binary expression system for use in zebrafish","year":2020,"lang":"en","type":"article","venue":"Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Ontario Institute for Cancer Research; University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","keywords":"Biology; Zebrafish; CpG site; Gene silencing; Transgene; DNA methylation; Effector; Genetics; Methylation; Gene; Transcription factor; Cell biology; Gene expression; Computational biology; Molecular biology","score_opus":0.016075037740114678,"score_gpt":0.2955461091544618,"score_spread":0.2794710714143471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042463377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9704802,0.00013765036,0.028743768,0.000053952073,0.00015070282,0.00027852,0.00003815967,0.000030989944,0.000086051485],"genre_scores_gemma":[0.9521274,0.000013792073,0.046815746,0.00027435154,0.000094759846,0.00006806111,0.00057299336,0.000017849781,0.000015079325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991862,0.000035543006,0.00019305025,0.00034396653,0.000028801647,0.00021244871],"domain_scores_gemma":[0.99974555,0.00001283295,0.000028771177,0.00010006606,0.000019306563,0.00009348198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007352407,0.00012829018,0.0001517399,0.000030045774,0.000035466328,0.000011686389,0.00014087414,0.00015205391,0.000007914577],"category_scores_gemma":[0.00003443255,0.00012334033,0.00003889782,0.00005387397,0.000022656517,0.0000045984525,0.00008218382,0.000047814512,0.000004680802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022014734,0.000020665899,0.0039140875,0.00002838098,0.00001087911,0.0000033248004,0.00009362291,0.00037053446,0.9943374,0.000014857181,0.00042496232,0.0005611807],"study_design_scores_gemma":[0.001555107,0.00035372068,0.0030056403,0.000019023302,0.0000039484667,0.000012939288,0.0003977955,0.0017457365,0.9821263,0.000002749636,0.010526257,0.00025081576],"about_ca_topic_score_codex":0.000006791181,"about_ca_topic_score_gemma":0.0000075398616,"teacher_disagreement_score":0.018352838,"about_ca_system_score_codex":0.000019555571,"about_ca_system_score_gemma":0.000035725043,"threshold_uncertainty_score":0.5029673},"labels":[],"label_agreement":null},{"id":"W3042717430","doi":"10.1525/elementa.429","title":"Tensions at the boundary: Rearticulating ‘organic’ plant breeding in the age of gene editing","year":2020,"lang":"en","type":"article","venue":"Elementa Science of the Anthropocene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Deliberation; Genome editing; Organic farming; Emerging technologies; Agriculture; Political science; Public relations; Biology; Politics; Gene; Computer science; Ecology; Genetics; Genome","score_opus":0.018479057755771265,"score_gpt":0.3013503647361603,"score_spread":0.28287130698038904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042717430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954772,0.00028664144,0.0003441586,0.00339884,0.00012683167,0.00014764027,0.000015159803,0.000002629289,0.0002008739],"genre_scores_gemma":[0.99896425,0.00004368462,0.00048345135,0.00035869222,0.00012628452,0.0000023527439,0.000007885457,0.000006262693,0.0000071423983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903494,0.00003159539,0.00021994894,0.00018791932,0.00031296563,0.00021263059],"domain_scores_gemma":[0.9995267,0.000019303174,0.00009330374,0.0002968044,0.00003772391,0.00002619033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006022615,0.00007800726,0.00009072336,0.000015786873,0.00032899398,0.000020470447,0.00055569,0.000020484553,0.00002269168],"category_scores_gemma":[0.00022911934,0.000041557054,0.00004886391,0.00035927937,0.00060779107,0.0000055128257,0.00037418818,0.00007337322,6.440328e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000049879804,0.000014157784,0.00711817,0.000008074438,0.000006108706,0.0000010784521,0.0004920573,0.00047546,0.9912664,0.000015585338,0.00043288377,0.00016501009],"study_design_scores_gemma":[0.00014801144,0.00009470254,0.011638112,0.00002357247,0.000012276153,0.000010689172,0.0017499955,0.00095722615,0.98481625,0.000008910168,0.00048564558,0.000054595635],"about_ca_topic_score_codex":0.00004289308,"about_ca_topic_score_gemma":0.000055847362,"teacher_disagreement_score":0.006450163,"about_ca_system_score_codex":0.000013171896,"about_ca_system_score_gemma":0.000051537743,"threshold_uncertainty_score":0.25303888},"labels":[],"label_agreement":null},{"id":"W3043009108","doi":"10.1080/23723556.2020.1789419","title":"Adding to the CASeload: unwarranted p53 signaling induced by Cas9","year":2020,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cancer Biology Research Center, Tel Aviv University; Azrieli Foundation; Tel Aviv University; Israel Cancer Association","keywords":"CRISPR; Palindrome; Cas9; Biology; P53 protein; Mutation; Genetics; Cancer research; Cell; Cell biology; Computational biology; Gene","score_opus":0.012874731779027034,"score_gpt":0.2895312999988123,"score_spread":0.27665656821978524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043009108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.821175,0.0025734287,0.17128928,0.0034951405,0.000285725,0.00044180255,0.000031874686,0.00004507766,0.00066268654],"genre_scores_gemma":[0.99337363,0.000021852275,0.0012875494,0.004657178,0.00025292905,0.00005173952,0.00020183415,0.00006254696,0.0000907209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833816,0.00015362479,0.00030258135,0.00056929066,0.00016214376,0.0004742039],"domain_scores_gemma":[0.9991887,0.000023701541,0.00006784491,0.0003981645,0.00007753388,0.00024406024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022223525,0.00027121016,0.00026220072,0.000039166265,0.00013354316,0.000033320088,0.0004253134,0.00026119716,0.000054490178],"category_scores_gemma":[0.00017874951,0.0002449834,0.00013183564,0.0002913232,0.000037431153,0.0000024068843,0.0002358657,0.00026122163,0.00008150643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049761104,0.000028672632,0.000016741998,0.0000124061435,0.00008207826,0.00009929338,0.00031323844,0.0027170754,0.98802596,0.000016536675,0.0054752347,0.0031629687],"study_design_scores_gemma":[0.00040266357,0.00048178103,0.000005630487,0.000005554931,0.000037365342,0.000024639461,0.00018174613,0.0003170728,0.723628,0.0000023028097,0.2746876,0.00022568587],"about_ca_topic_score_codex":0.00003886866,"about_ca_topic_score_gemma":0.000016466176,"teacher_disagreement_score":0.26921237,"about_ca_system_score_codex":0.000035542977,"about_ca_system_score_gemma":0.00011284329,"threshold_uncertainty_score":0.9990134},"labels":[],"label_agreement":null},{"id":"W3043164109","doi":"10.1016/j.imlet.2020.07.003","title":"Utilization of CRISPR/Cas9 gene editing in cellular therapies for lymphoid malignancies","year":2020,"lang":"en","type":"review","venue":"Immunology Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Michener Institute","funders":"","keywords":"CRISPR; Genome editing; Immune system; Cas9; Genetic enhancement; Biology; Lymphoma; Cancer research; Computational biology; Immunology; Gene; Genetics","score_opus":0.02508918620011574,"score_gpt":0.31925110448163607,"score_spread":0.29416191828152033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043164109","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017750473,0.9694761,0.027672762,0.00012684887,0.0004296269,0.0004446236,0.000053675532,0.0000120905615,0.000009224113],"genre_scores_gemma":[0.002248522,0.995491,0.0010664795,0.0001425297,0.00032467736,0.0001411508,0.00050768594,0.000060518487,0.0000174056],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987727,0.000072572635,0.0004676544,0.00036178998,0.00005786093,0.00026742675],"domain_scores_gemma":[0.99942553,0.000034972305,0.00020353575,0.00028160494,0.00003455261,0.000019800604],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012019048,0.00028659092,0.00072105695,0.00011734375,0.000029539764,0.000008498826,0.00026132804,0.00032410983,0.000004721192],"category_scores_gemma":[0.00007540985,0.00028299243,0.00027768489,0.00012340552,0.0000895183,0.00000226373,0.00008992953,0.000110646,0.0000022751817],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024508976,0.00002835997,0.000038999624,0.0035669238,0.00048551353,0.000012432711,0.0001693856,0.00006934965,0.63739944,0.000032457014,0.0006244831,0.35754815],"study_design_scores_gemma":[0.00031539917,0.00008946668,0.000008208753,0.0005598152,0.00012158536,0.000028286078,0.000046968355,0.00001124465,0.14411075,0.0000042930556,0.85445595,0.00024800238],"about_ca_topic_score_codex":0.000008061515,"about_ca_topic_score_gemma":0.0000032557737,"teacher_disagreement_score":0.85383147,"about_ca_system_score_codex":0.000026413796,"about_ca_system_score_gemma":0.000068387475,"threshold_uncertainty_score":0.9999622},"labels":[],"label_agreement":null},{"id":"W3043916478","doi":"10.1038/s41598-020-68934-y","title":"A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; McGill University","funders":"Canadian Institutes of Health Research; Université du Québec à Montréal; Natural Sciences and Engineering Research Council of Canada; Government of Canada; McGill University","keywords":"Biology; Computational biology; CRISPR; Genome; Virology; Influenza A virus; Virus; Gene; Genetics","score_opus":0.017354052564422205,"score_gpt":0.29199831727778247,"score_spread":0.2746442647133603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043916478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885246,0.00031133712,0.009997499,0.00010467366,0.00063201296,0.00036979467,0.0000023603611,0.000024664323,0.00003306267],"genre_scores_gemma":[0.99922574,0.000008964723,0.0003762332,0.00008055496,0.00009333025,0.000014013321,0.00010483784,0.000017336219,0.00007900541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984804,0.000011762945,0.0003648458,0.00071422313,0.00019209458,0.00023666436],"domain_scores_gemma":[0.99932843,0.0000055153755,0.00010182167,0.00032532812,0.00007127658,0.00016760842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037554617,0.00014880965,0.00013563954,0.0001459626,0.00010777702,0.00012118334,0.00007228421,0.000082849874,0.000008447832],"category_scores_gemma":[0.00024342327,0.00014265023,0.000043629807,0.00044065484,0.000022128406,0.000013620162,0.00006549044,0.00009298,0.0000018791118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003938775,0.000015787498,0.0715213,0.000033261185,0.000007594573,0.000022180868,0.0001431415,0.038370054,0.8892598,2.225661e-7,0.00040645266,0.00018079931],"study_design_scores_gemma":[0.00030290952,0.00015274566,0.23085263,0.000018237813,0.000016024685,0.000010758926,0.0002243596,0.00034059197,0.7636669,0.000021480819,0.0041769505,0.00021635574],"about_ca_topic_score_codex":0.00002831222,"about_ca_topic_score_gemma":0.000043800275,"teacher_disagreement_score":0.15933134,"about_ca_system_score_codex":0.000014308022,"about_ca_system_score_gemma":0.000059262904,"threshold_uncertainty_score":0.58171076},"labels":[],"label_agreement":null},{"id":"W3044027650","doi":"10.3389/fpls.2020.01126","title":"CRISPR/Cas9 Gene Editing: An Unexplored Frontier for Forest Pathology","year":2020,"lang":"en","type":"review","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Natural Resources Canada; Canadian Forest Service; University of British Columbia","funders":"Natural Resources Canada; FPInnovations; Canadian Food Inspection Agency; Genome Canada","keywords":"CRISPR; Genome editing; Cas9; Biology; Computational biology; Gene; Plasmid; Trans-activating crRNA; Genetics","score_opus":0.02445535397690733,"score_gpt":0.33046541709517263,"score_spread":0.3060100631182653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044027650","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000110324545,0.81602746,0.17939572,0.00002055057,0.0031966167,0.00068792014,0.00047781004,0.000021775082,0.00006180934],"genre_scores_gemma":[0.00021827142,0.9507745,0.046341233,0.00006736681,0.0010190333,0.0002378993,0.0012023147,0.000062623905,0.00007678151],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99747664,0.000052152078,0.000494421,0.0010893614,0.0002219843,0.000665457],"domain_scores_gemma":[0.99898714,0.00001523937,0.00017407378,0.0005333227,0.00005619172,0.00023406172],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00051146455,0.000408446,0.0009083171,0.00027345156,0.00012718941,0.000063267646,0.0010040278,0.00034607554,0.0000016170468],"category_scores_gemma":[0.00025700734,0.0003799921,0.00021556087,0.00038255128,0.00028354718,0.000013339411,0.00021290059,0.00023321374,0.0000029984642],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078920595,0.000111840316,0.0004504762,0.003184345,0.00011106462,0.00019084166,0.00026494957,0.0004807345,0.003153739,0.00009239919,0.05382457,0.9380561],"study_design_scores_gemma":[0.00026161165,0.00022978465,0.000022669505,0.00033391523,0.00009214564,0.0001137499,0.00008672102,0.0012815811,0.0009231585,0.000058315338,0.9961335,0.00046286723],"about_ca_topic_score_codex":0.000004204715,"about_ca_topic_score_gemma":0.000017700037,"teacher_disagreement_score":0.9423089,"about_ca_system_score_codex":0.00006383213,"about_ca_system_score_gemma":0.0004053863,"threshold_uncertainty_score":0.9998652},"labels":[],"label_agreement":null},{"id":"W3044578251","doi":"10.1101/2020.07.28.201152","title":"Combinatorial CRISPR screening reveals functional buffering in autophagy","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Deutsche Forschungsgemeinschaft","keywords":"Guide RNA; Biology; CRISPR; Functional genomics; Computational biology; Gene; Phenotype; Autophagy; Context (archaeology); Genetics; Genome; Genome editing; Genomics","score_opus":0.014290065438252805,"score_gpt":0.2519202845989808,"score_spread":0.237630219160728,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044578251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92035073,0.0028486138,0.07213162,0.00023245123,0.003439512,0.0006572929,0.00010091834,0.00020407067,0.00003481883],"genre_scores_gemma":[0.9931143,0.00018285951,0.0043146764,0.0002067605,0.0018805951,0.00014126355,0.0000037788325,0.0001499483,0.000005852098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99722064,0.00009653006,0.00058378454,0.0011739283,0.00033897796,0.00058617233],"domain_scores_gemma":[0.99843466,0.000024485536,0.00019567781,0.00086917955,0.00019153008,0.00028447344],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004122635,0.00057345896,0.0005345356,0.00017912572,0.00009336932,0.00012315695,0.00047556707,0.00070333376,0.000028683198],"category_scores_gemma":[0.00029768466,0.0007143221,0.00020839508,0.00028529813,0.00006118043,0.0000088107045,0.0008326721,0.00078753935,0.000020057492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007806168,0.000059713904,0.005107629,0.00020639223,0.000115944495,0.000044955195,0.0000050773965,0.0028984423,0.9904432,0.0004090999,0.0006282659,0.0000031709833],"study_design_scores_gemma":[0.0013346416,0.00011729621,0.15419522,0.00027823358,0.00006587106,6.596142e-8,0.000004003236,0.0013246159,0.8334759,0.000012368802,0.008112769,0.0010790386],"about_ca_topic_score_codex":0.00003696583,"about_ca_topic_score_gemma":0.0000033105005,"teacher_disagreement_score":0.15696737,"about_ca_system_score_codex":0.00009965808,"about_ca_system_score_gemma":0.00027942067,"threshold_uncertainty_score":0.9995308},"labels":[],"label_agreement":null},{"id":"W3044710522","doi":"10.1016/j.molcel.2020.07.005","title":"Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Transgenic Science and Technology Program; Youth Innovation Promotion Association of the Chinese Academy of Sciences; National Natural Science Foundation of China; United Soybean Board","keywords":"Biology; Cas9; Cytidine deaminase; Computational biology; Genome; genomic DNA; Cytosine; Genetics; Cytidine; DNA; Gene; Biochemistry; Enzyme","score_opus":0.005181607873979125,"score_gpt":0.2164771484335223,"score_spread":0.2112955405595432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044710522","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3168049,0.00048335973,0.67917717,0.000982071,0.00020992126,0.0002878348,0.00001648502,0.00003967496,0.0019985996],"genre_scores_gemma":[0.9841254,0.000015084423,0.013664631,0.00091935217,0.00091287924,0.000015796844,0.00013490331,0.00004373292,0.00016824549],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990904,0.000027236061,0.00014708609,0.00037364347,0.00014943627,0.00021219818],"domain_scores_gemma":[0.99947155,0.0000051912343,0.00004043868,0.00024563062,0.00007254648,0.00016465642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057439673,0.00018194472,0.000120573546,0.000019500769,0.00004359019,0.000027892977,0.000151638,0.000090139845,0.000041136536],"category_scores_gemma":[0.000029231962,0.0001709622,0.00007204286,0.0001045835,0.000031223593,0.000002481972,0.000058646514,0.00008498889,0.000016370223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009674084,0.000033896416,0.00008623312,0.000019136289,0.000023345747,0.000022765193,0.0000270651,0.0033443714,0.9926776,0.000012327023,0.003458096,0.00019838577],"study_design_scores_gemma":[0.00065902853,0.0004112179,0.00008923588,0.0000038996723,0.000021454098,0.0000035783066,0.000023801489,0.001415859,0.9692583,0.000003433736,0.02787661,0.00023359946],"about_ca_topic_score_codex":0.0000050035833,"about_ca_topic_score_gemma":0.000003982581,"teacher_disagreement_score":0.6673205,"about_ca_system_score_codex":0.000008036627,"about_ca_system_score_gemma":0.00008133785,"threshold_uncertainty_score":0.69716364},"labels":[],"label_agreement":null},{"id":"W3045962899","doi":"10.1016/j.stem.2020.06.023","title":"Mapping Gene Circuits Essential for Germ Layer Differentiation via Loss-of-Function Screens in Haploid Human Embryonic Stem Cells","year":2020,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; United States-Israel Binational Science Foundation; Rosetrees Trust","keywords":"Biology; Embryonic stem cell; Induced pluripotent stem cell; Cell biology; Germ layer; Stem cell; Cellular differentiation; Genetics; Germ cell; Gene","score_opus":0.015984030407942964,"score_gpt":0.2454506247825058,"score_spread":0.22946659437456282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045962899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7803998,0.00078304537,0.21799757,0.000020496738,0.00021303023,0.00035030188,0.000018770475,0.000015642268,0.00020133366],"genre_scores_gemma":[0.9987137,0.0000639326,0.0001427217,0.000047560694,0.00029161363,0.000026929833,0.0001294785,0.000043657652,0.0005404463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988212,0.000031272924,0.0003336268,0.00041554435,0.000120027464,0.00027833323],"domain_scores_gemma":[0.9994693,0.000011379883,0.00013547204,0.00022966405,0.00006091463,0.00009329112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000093166134,0.00019698443,0.00021898793,0.000060694325,0.000057377587,0.000018549546,0.00015587696,0.00017500504,0.000016048509],"category_scores_gemma":[0.0000011176206,0.00022230526,0.00013929437,0.00011369995,0.000019790283,0.0000050568215,0.000074176736,0.00009163313,0.0000087735625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027366003,0.000060198145,0.00070368825,0.00036519507,0.000020744366,0.0000014799035,0.0001737972,0.002753195,0.9947745,0.000004604014,0.00014089224,0.00097433914],"study_design_scores_gemma":[0.0010195837,0.00022636114,0.0012826371,0.000015109572,0.000031522868,8.5128426e-7,0.00012545414,0.002319915,0.9932296,0.000006602368,0.0015087402,0.00023358548],"about_ca_topic_score_codex":0.0000075076055,"about_ca_topic_score_gemma":0.000011949745,"teacher_disagreement_score":0.21831384,"about_ca_system_score_codex":0.000018292643,"about_ca_system_score_gemma":0.00003095316,"threshold_uncertainty_score":0.90653455},"labels":[],"label_agreement":null},{"id":"W3046230645","doi":"10.1148/rycan.2020190053","title":"Interrogating Cellular Communication in Cancer with Genetically Encoded Imaging Reporters","year":2020,"lang":"en","type":"review","venue":"Radiology Imaging Cancer","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Molecular imaging; Computational biology; Context (archaeology); Translation (biology); Live cell imaging; Photoacoustic imaging in biomedicine; Drug discovery; Biology; Genome editing; Gene; Cell biology; Genome; Cell; Bioinformatics; In vivo; Genetics; Messenger RNA","score_opus":0.014921369137543248,"score_gpt":0.35848056970177783,"score_spread":0.34355920056423456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046230645","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005362751,0.99265456,0.0055524255,0.00029479637,0.00025589322,0.0004454313,0.000027937385,0.00003478367,0.00019788941],"genre_scores_gemma":[0.009889265,0.98682576,0.0018351373,0.00025014003,0.00034707153,0.00044190438,0.0002447651,0.000114324816,0.000051631065],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977896,0.00019376646,0.0006562491,0.00078660646,0.00010956024,0.00046418927],"domain_scores_gemma":[0.9987918,0.000036412115,0.0003361144,0.0006607122,0.00006233776,0.00011262985],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021956004,0.00047911852,0.0009682817,0.000126809,0.00006343536,0.00003391831,0.00048382708,0.00017779304,0.000032514232],"category_scores_gemma":[0.0000533525,0.00043323176,0.00019440675,0.00021303874,0.0001906783,0.000005739692,0.0002140686,0.0005238407,0.0000031546215],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021760492,0.000020173557,0.0026294235,0.0017873163,0.00027672868,0.00010946838,0.00024984154,0.00082170166,0.0044843624,0.000004778666,0.0006551499,0.9889393],"study_design_scores_gemma":[0.00055042875,0.000048356702,0.0000671812,0.005636016,0.00051474763,0.00044726435,0.00012625352,0.0019246448,0.0015884037,0.0000069565863,0.9881898,0.0008999436],"about_ca_topic_score_codex":0.00020397619,"about_ca_topic_score_gemma":0.00026636256,"teacher_disagreement_score":0.9880394,"about_ca_system_score_codex":0.00017874164,"about_ca_system_score_gemma":0.00045210726,"threshold_uncertainty_score":0.99981195},"labels":[],"label_agreement":null},{"id":"W3046596788","doi":"10.3389/fgene.2020.00855","title":"Radioresistance, DNA Damage and DNA Repair in Cells With Moderate Overexpression of RPA1","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Ural Branch, Russian Academy of Sciences; Institut de Radioprotection et de SÛreté Nucléaire","keywords":"Radioresistance; DNA damage; DNA repair; DNA; Cell biology; Biology; Molecular biology; Genetics; Cell culture","score_opus":0.004420824142957506,"score_gpt":0.22100647361152723,"score_spread":0.21658564946856973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046596788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.974299,0.0033127829,0.021904187,0.00005309384,0.00007061666,0.00016372392,0.000024057928,0.000008349418,0.00016416448],"genre_scores_gemma":[0.96076065,0.00089140236,0.038086336,0.00010984105,0.000047389174,0.000006619667,0.000014393668,0.000023442894,0.000059918548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992003,0.000028440249,0.000203113,0.00029400658,0.00009428143,0.00017984757],"domain_scores_gemma":[0.9996482,0.0000040846994,0.000044404573,0.00020673452,0.000020071968,0.00007647932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006143873,0.00013599885,0.00019159466,0.000047970472,0.000013771646,0.0000059784375,0.00010250435,0.000103049126,0.0000019756947],"category_scores_gemma":[0.000012544827,0.00013288597,0.000029941337,0.000117508825,0.000061633364,0.0000025292914,0.0000672681,0.000081689475,1.53381e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031608777,0.000030812847,0.021411242,0.00012684043,0.00002318515,0.000009656426,0.0003278589,0.025175212,0.94644487,0.0000040122327,0.005651118,0.0004791323],"study_design_scores_gemma":[0.0011740347,0.00027127186,0.012525981,0.00007505061,0.000012172175,0.0000014563827,0.00021609143,0.025206322,0.95507133,0.000030374178,0.005182633,0.00023327602],"about_ca_topic_score_codex":0.0000035857786,"about_ca_topic_score_gemma":0.000015476444,"teacher_disagreement_score":0.016182149,"about_ca_system_score_codex":0.000008432459,"about_ca_system_score_gemma":0.000030279449,"threshold_uncertainty_score":0.54189324},"labels":[],"label_agreement":null},{"id":"W3046653028","doi":"10.1016/j.scr.2020.101930","title":"Generation of a Junctophilin-2 homozygous knockout human embryonic stem cell line (WAe009-A-36) by an episomal vector-based CRISPR/Cas9 system","year":2020,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Science Foundation of Beijing Municipality; National Natural Science Foundation of China","keywords":"Biology; Embryonic stem cell; Cell biology; CRISPR; Stem cell; Germline; Germ layer; Myofilament; Molecular biology; Genetics; Gene; Myocyte; Induced pluripotent stem cell","score_opus":0.06562680782180927,"score_gpt":0.3576540535833208,"score_spread":0.2920272457615115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046653028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832902,0.004286511,0.010309012,0.00013762854,0.00015786036,0.000643443,0.000108303415,0.000051639174,0.0010154018],"genre_scores_gemma":[0.99682426,0.000060994815,0.0001593974,0.00003909537,0.0006358906,0.000060504684,0.00033455974,0.00008238121,0.0018029378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970814,0.00037532265,0.00048645382,0.0007759646,0.00064014096,0.00064072385],"domain_scores_gemma":[0.9983632,0.000040001207,0.00010693894,0.00073783065,0.00036758068,0.00038443925],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006948475,0.00029557061,0.00035821224,0.00012124936,0.00021435664,0.00007224762,0.0005194345,0.00029594853,0.000024695182],"category_scores_gemma":[0.000008959651,0.00029964233,0.00015887815,0.00033028016,0.00009798326,0.00000778857,0.00018770633,0.00036961157,0.000033978173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110049645,0.00014464665,0.000086767104,0.0007785145,0.000023162691,0.000022688077,0.00015875185,0.0036637955,0.9912297,0.000018667804,0.0025109437,0.0012522923],"study_design_scores_gemma":[0.0010624955,0.0020300741,0.000057912417,0.00003212172,0.000022826045,0.0000051916077,0.0005838615,0.017049553,0.9735273,7.057432e-7,0.0053359955,0.00029196535],"about_ca_topic_score_codex":0.00006244517,"about_ca_topic_score_gemma":0.000041553034,"teacher_disagreement_score":0.017702421,"about_ca_system_score_codex":0.000070611735,"about_ca_system_score_gemma":0.0002440768,"threshold_uncertainty_score":0.9999456},"labels":[],"label_agreement":null},{"id":"W3046697187","doi":"10.1007/s41649-020-00136-0","title":"Framing Ethical Concerns and Attitudes towards Human Gene Patents in the Chinese Press","year":2020,"lang":"en","type":"article","venue":"Asian Bioethics Review","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics","funders":"Universidade de Macau; Ministry of Science and Technology of the People's Republic of China","keywords":"Patentability; Newspaper; Framing (construction); China; Political science; Commercialization; Bioethics; Supreme court; Normative; Competence (human resources); Human rights; Law; Public relations; Sociology; Intellectual property; Patent law; Psychology; Social psychology; Engineering","score_opus":0.07441487818399509,"score_gpt":0.4260657202155946,"score_spread":0.35165084203159946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046697187","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21415101,0.6993727,0.005335589,0.075792156,0.00020543678,0.0016626163,0.000060478666,0.000053148447,0.0033668731],"genre_scores_gemma":[0.9173136,0.07427871,0.00033745868,0.0077903513,0.00019276617,0.000022200717,0.000042384152,0.00001402912,0.000008530538],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99907273,0.00012777562,0.00021773935,0.00027234651,0.00015107323,0.00015830566],"domain_scores_gemma":[0.9996099,0.000015026926,0.00004107018,0.00022667408,0.000032333108,0.00007502609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044523232,0.00014545646,0.00019753279,0.000008195836,0.000055451415,0.000028464308,0.00023876922,0.00023487207,0.0000071436866],"category_scores_gemma":[0.00023753481,0.00010110202,0.0000620307,0.00009757059,0.00013128409,0.0000019181036,0.00012976034,0.00050647574,0.0000022462166],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011787756,0.00051430945,0.090123236,0.04877564,0.0007710895,0.0004061366,0.016578708,0.00021743828,0.56770605,0.008435449,0.014567222,0.25178683],"study_design_scores_gemma":[0.003922123,0.0021876276,0.34467676,0.006993203,0.00051124365,0.0003165557,0.00091344846,0.0006335458,0.07715769,0.0006819821,0.55866814,0.00333768],"about_ca_topic_score_codex":0.000048654783,"about_ca_topic_score_gemma":0.00006623573,"teacher_disagreement_score":0.70316255,"about_ca_system_score_codex":0.0000034310638,"about_ca_system_score_gemma":0.00002574125,"threshold_uncertainty_score":0.41228208},"labels":[],"label_agreement":null},{"id":"W3046843508","doi":"10.1101/2020.07.31.230565","title":"Specific mutations in genes responsible for Alzheimer and for Duchenne Muscular Dystrophy introduced by Base editing and PRIME editing","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research; Fondation CHU de Québec; Centre Hospitalier Universitaire de Québec; Weston Brain Institute","keywords":"Genome editing; Duchenne muscular dystrophy; Exon; Genetics; Gene; Point mutation; Biology; Dystrophin; Mutation; CRISPR; Muscular dystrophy; Gene mutation","score_opus":0.01569023266425092,"score_gpt":0.26021647640813583,"score_spread":0.2445262437438849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046843508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9205378,0.017908763,0.057975296,0.0006750255,0.0006826601,0.0014303203,0.0007293756,0.00005976131,9.4398473e-7],"genre_scores_gemma":[0.9526825,0.00044892248,0.044074744,0.00006615175,0.0020801125,0.0005058717,0.00001840833,0.00012161688,0.0000017007305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793774,0.000051639843,0.00041767777,0.0010545364,0.00011506829,0.00042334961],"domain_scores_gemma":[0.99888283,0.000064994936,0.00017004138,0.00045895466,0.00023256912,0.0001905824],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045083556,0.00039499087,0.00038393788,0.00013208587,0.00012969533,0.00012678995,0.00017444161,0.0003534465,0.0000021095484],"category_scores_gemma":[0.00044396913,0.0004750355,0.000098581724,0.00013871395,0.00007776936,0.00001040135,0.00026691807,0.0002395687,5.9919586e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006644095,0.000028200891,0.00039688096,0.00026811377,0.00014302526,0.000003903538,0.00001200167,0.00021081668,0.9981363,0.000045731816,0.00065706694,0.000031514326],"study_design_scores_gemma":[0.000977607,0.00012591152,0.0020234168,0.000099546254,0.00014621802,6.499055e-8,0.000015596795,0.0017268,0.9806445,0.000004934839,0.01374146,0.00049391994],"about_ca_topic_score_codex":0.0000112820435,"about_ca_topic_score_gemma":0.0000026488492,"teacher_disagreement_score":0.032144617,"about_ca_system_score_codex":0.000028694729,"about_ca_system_score_gemma":0.00015399435,"threshold_uncertainty_score":0.9997701},"labels":[],"label_agreement":null},{"id":"W3046932746","doi":"10.1158/1538-7445.pedca19-a23","title":"Abstract A23: Novel approaches to Ewing sarcoma therapy","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"PARP1; DNA damage; Cancer research; Synthetic lethality; FLI1; Biology; Sarcoma; Cancer; Pediatric cancer; DNA repair; DNA; Chromosomal translocation; Medicine; Gene; Genetics; Poly ADP ribose polymerase; Pathology","score_opus":0.2969357991154682,"score_gpt":0.4314839166845446,"score_spread":0.13454811756907642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046932746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98656803,0.0030667677,0.005862542,0.0028431932,0.000057813184,0.00025254034,0.000015956892,0.000015010454,0.0013181698],"genre_scores_gemma":[0.997834,0.00032468408,0.0005732648,0.00037256716,0.0006488827,0.00008276028,0.0000120962195,0.000027011203,0.00012472046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902946,0.000015362972,0.00009535065,0.00031943942,0.00020962875,0.00033074155],"domain_scores_gemma":[0.9995255,0.000011916268,0.000008665523,0.00020531319,0.0000501843,0.00019841142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021354399,0.000090711634,0.00008381265,0.00003576153,0.00006816497,0.000036081557,0.0002515013,0.00006606079,0.000057089797],"category_scores_gemma":[0.000056782395,0.00008578693,0.00004360607,0.00018268592,0.00003409366,0.0000018594081,0.00012740062,0.0001717603,0.000024560835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006842866,0.000023034756,0.00033118378,0.000023043345,0.000023639255,0.0000014810216,0.0002528741,0.0012050177,0.98036075,0.00002488271,0.0023460123,0.0153396595],"study_design_scores_gemma":[0.0003807723,0.00014375297,0.0041859904,0.000010644636,0.0000010009692,9.942963e-7,0.00013787884,0.0000940092,0.8808372,0.0000058570586,0.11407758,0.00012431382],"about_ca_topic_score_codex":0.000042407813,"about_ca_topic_score_gemma":0.000011795901,"teacher_disagreement_score":0.11173157,"about_ca_system_score_codex":0.000015870532,"about_ca_system_score_gemma":0.000081413054,"threshold_uncertainty_score":0.34982896},"labels":[],"label_agreement":null},{"id":"W3047067051","doi":"10.1158/1538-7445.pedca19-b19","title":"Abstract B19: Identification of physiologically relevant EWS-FLI1 target genes in Ewing’s sarcoma via CRISPRa screening","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Ewing's sarcoma; Biology; Gene; Sarcoma; Fusion gene; CD44; Pediatric cancer; Computational biology; Cancer research; Cancer; Genetics; Cell; Medicine; Pathology","score_opus":0.05857783347540065,"score_gpt":0.4087653837980935,"score_spread":0.3501875503226929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047067051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98011255,0.00479014,0.014096634,0.00057793176,0.000055374265,0.00022221298,0.000021594611,0.000010498062,0.000113058595],"genre_scores_gemma":[0.9976519,0.0010237973,0.0008581736,0.000063725325,0.00024031305,0.000052356663,0.000042860112,0.000019450332,0.000047440662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986915,0.000062632396,0.00030640405,0.00036506553,0.0002563624,0.0003180093],"domain_scores_gemma":[0.9994215,0.000025756906,0.000053140095,0.00024082608,0.00015846072,0.000100335594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045717647,0.00010457613,0.00015311329,0.00006448534,0.000049154783,0.000018459683,0.00028750912,0.00010767716,0.000060810493],"category_scores_gemma":[0.00016318931,0.0000998655,0.00006051433,0.00023972886,0.00008143462,0.0000053177514,0.00015215171,0.00022812033,0.000007969203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010962052,0.000025645764,0.0018743386,0.00009310775,0.00001788385,0.000004203015,0.000111074085,0.0047747786,0.9831505,0.000007896724,0.0004944316,0.009336563],"study_design_scores_gemma":[0.00028004125,0.00012981631,0.05082018,0.00002782424,0.0000025890542,8.3056557e-7,0.00011932968,0.0012712775,0.9431995,0.000052644464,0.0039785933,0.0001173747],"about_ca_topic_score_codex":0.00012281626,"about_ca_topic_score_gemma":0.000020745367,"teacher_disagreement_score":0.04894584,"about_ca_system_score_codex":0.000018863835,"about_ca_system_score_gemma":0.00007094707,"threshold_uncertainty_score":0.4072397},"labels":[],"label_agreement":null},{"id":"W3047155545","doi":"10.1158/1538-7445.pedca19-a22","title":"Abstract A22: YAP1 knockout in vitro models of medulloblastoma showed improved response to sonidegib","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Propidium iodide; Cancer research; Medulloblastoma; Cell growth; Biology; YAP1; Apoptosis; Cell culture; Molecular biology; Internal medicine; Medicine; Programmed cell death; Genetics","score_opus":0.046194195735284826,"score_gpt":0.402369820234393,"score_spread":0.35617562449910817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047155545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951283,0.0011685637,0.0015289361,0.0015352165,0.00004772779,0.00031805693,0.000042457956,0.00000892996,0.00022185664],"genre_scores_gemma":[0.9988277,0.00014224356,0.0004350697,0.00014007218,0.00013748594,0.000102971346,0.0000070044425,0.000029000346,0.00017843318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986876,0.000077726116,0.0002148384,0.00036606716,0.0002458322,0.00040791024],"domain_scores_gemma":[0.9992801,0.00004326363,0.000021487574,0.00028458465,0.00014729433,0.00022326804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005712655,0.000113638205,0.00016638826,0.00010574462,0.000028792407,0.000015457224,0.00029854474,0.0001081055,0.0000366162],"category_scores_gemma":[0.00028675533,0.00011715374,0.000058181326,0.00029913255,0.00005317759,0.0000037132406,0.0002028604,0.00022069948,0.0000071538616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034181296,0.00002105694,0.00003243979,0.00005420472,0.000016646429,0.0000054959646,0.00035581348,0.0066560004,0.9842474,0.0000026937842,0.0006761569,0.004513956],"study_design_scores_gemma":[0.00052671693,0.00025676037,0.0012471011,0.00003006215,0.0000020503958,7.5605175e-7,0.00017540486,0.0019186365,0.9919539,0.00001557327,0.0037489007,0.00012411008],"about_ca_topic_score_codex":0.00017214265,"about_ca_topic_score_gemma":0.000103422084,"teacher_disagreement_score":0.0077065215,"about_ca_system_score_codex":0.00004434619,"about_ca_system_score_gemma":0.00026866674,"threshold_uncertainty_score":0.4777391},"labels":[],"label_agreement":null},{"id":"W3047331065","doi":"10.1080/14636778.2020.1799343","title":"The consumer representation of DNA ancestry testing on YouTube","year":2020,"lang":"en","type":"article","venue":"New Genetics and Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Canadian Institutes of Health Research; Genome Alberta; Genome Canada","keywords":"Genetic genealogy; Ethnic group; Race (biology); Representation (politics); Promotion (chess); Identity (music); Social media; Phrase; Psychology; Sociology; Anthropology; Gender studies; Computer science; World Wide Web; Political science; Demography; Law; Politics; Aesthetics","score_opus":0.03842493702971653,"score_gpt":0.3211931823059316,"score_spread":0.282768245276215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047331065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99298924,0.0028167437,0.0030606135,0.00043470238,0.00006864592,0.00008408442,0.0000058119017,0.0000065105824,0.00053363765],"genre_scores_gemma":[0.9948115,0.0018466954,0.002708328,0.00032267976,0.00021970156,0.0000015508595,0.0000072942194,0.000009618958,0.000072632276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995374,0.000009723513,0.00011499125,0.00015937927,0.00007744098,0.0001010777],"domain_scores_gemma":[0.99969614,0.000028574803,0.00003758961,0.00013079678,0.00003781546,0.000069063906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004357878,0.00007101863,0.00006748456,0.0000021173123,0.00007138312,0.000016343609,0.00007139131,0.00005894975,0.0000012173678],"category_scores_gemma":[0.000067473855,0.00005675409,0.00005257456,0.000060736173,0.000054074684,7.2026967e-7,0.00004905329,0.000052378884,6.0300255e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019237186,0.000011370932,0.008916391,0.000027510314,0.00006536528,3.0708043e-7,0.00074507797,0.0020693692,0.9383678,0.000060388407,0.0082339775,0.041483194],"study_design_scores_gemma":[0.00082729623,0.00058148865,0.033455186,0.00001647043,0.00003889046,0.000004226763,0.0013860719,0.007948794,0.9241973,0.00010487089,0.031188782,0.00025060461],"about_ca_topic_score_codex":0.0000058849287,"about_ca_topic_score_gemma":0.0000019211789,"teacher_disagreement_score":0.04123259,"about_ca_system_score_codex":0.0000016388188,"about_ca_system_score_gemma":0.000027623679,"threshold_uncertainty_score":0.23143645},"labels":[],"label_agreement":null},{"id":"W3047419816","doi":"10.1016/j.ymben.2020.07.008","title":"Improving CRISPR/Cas9-mediated genome editing efficiency in Yarrowia lipolytica using direct tRNA-sgRNA fusions","year":2020,"lang":"en","type":"article","venue":"Metabolic Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Université Laval; U.S. Department of Energy","keywords":"Yarrowia; Genome editing; CRISPR; Cas9; Biology; Guide RNA; Gene; Subgenomic mRNA; Genetics; Computational biology; Saccharomyces cerevisiae; Homologous recombination; RNA editing; RNA","score_opus":0.008983810513779241,"score_gpt":0.25123414329861177,"score_spread":0.24225033278483252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047419816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8506216,0.0072390074,0.14090385,0.00010551399,0.0004692713,0.00025343816,0.000025985419,0.00011993307,0.00026139672],"genre_scores_gemma":[0.99189484,0.00018507298,0.0066872225,0.00013491545,0.00093771156,0.000019523353,0.000036443646,0.00008464251,0.000019642152],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9981952,0.000027104566,0.00042925842,0.00052228867,0.0001965208,0.00062963774],"domain_scores_gemma":[0.99930245,0.000027717459,0.00006855056,0.0002963771,0.000042083895,0.0002628005],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023946255,0.0003264151,0.00036996062,0.00015798454,0.00007462116,0.000044778768,0.00027923757,0.00015980008,0.00002307036],"category_scores_gemma":[0.00065859227,0.00035935387,0.00013468537,0.00051697704,0.000023149953,0.000011686917,0.00020507624,0.00027600696,0.000009808223],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000658626,0.00001698768,0.00044063723,0.000050514034,0.000023768616,0.00001193898,0.00019830263,0.16739297,0.8312957,0.000011798219,0.000009401036,0.0005413371],"study_design_scores_gemma":[0.0010213202,0.00010070592,0.0061456505,0.000053418433,0.00007876126,0.000027962082,0.00017154496,0.59992874,0.37179142,8.36157e-7,0.019865662,0.0008139916],"about_ca_topic_score_codex":0.00006534245,"about_ca_topic_score_gemma":0.00000981319,"teacher_disagreement_score":0.45950434,"about_ca_system_score_codex":0.00002334555,"about_ca_system_score_gemma":0.000058969355,"threshold_uncertainty_score":0.99988586},"labels":[],"label_agreement":null},{"id":"W3047477123","doi":"10.1016/j.jcyt.2020.06.008","title":"High-throughput assessment of mutations generated by genome editing in induced pluripotent stem cells by high-resolution melting analysis","year":2020,"lang":"en","type":"article","venue":"Cytotherapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"High Resolution Melt; Induced pluripotent stem cell; High resolution; Genome editing; Biology; Genome; Throughput; Embryonic stem cell; Computational biology; Genetics; Gene; Computer science; Geography; Polymerase chain reaction; Operating system","score_opus":0.011082684863585051,"score_gpt":0.2822518430653138,"score_spread":0.27116915820172877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047477123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8447327,0.0007278125,0.15400851,0.00019393036,0.00006890173,0.00014143942,0.00010175948,0.000013964771,0.000010952648],"genre_scores_gemma":[0.9954416,0.00018814059,0.0034603644,0.00017233325,0.0001611343,0.00002121311,0.00050147006,0.000026149037,0.000027555581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988808,0.000060835897,0.00036342768,0.00034202714,0.00014169414,0.00021119867],"domain_scores_gemma":[0.9995551,0.000010231215,0.0001302083,0.00017369019,0.0000580949,0.000072650335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113727896,0.00015587485,0.00025283554,0.00006571119,0.000044830467,0.0000185327,0.00012304509,0.00011461212,0.00002582506],"category_scores_gemma":[0.0000055302976,0.00016764416,0.00008795264,0.00041148125,0.000020033516,0.0000046341625,0.00003075496,0.0000958101,9.5050336e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009497611,0.000039342525,0.00063759193,0.0000125542165,0.00021470108,8.92896e-7,0.00012757939,0.09162161,0.90652275,0.000007432733,0.0002048808,0.000601167],"study_design_scores_gemma":[0.0007753581,0.0001759793,0.00182569,0.0000051634747,0.00006647815,3.0442763e-7,0.00018898294,0.01842349,0.9775953,0.000002324714,0.0007606973,0.0001802097],"about_ca_topic_score_codex":0.00016878096,"about_ca_topic_score_gemma":0.000029521001,"teacher_disagreement_score":0.15070891,"about_ca_system_score_codex":0.000037359136,"about_ca_system_score_gemma":0.000035604433,"threshold_uncertainty_score":0.683633},"labels":[],"label_agreement":null},{"id":"W3047501588","doi":"10.1093/noajnl/vdaa073.025","title":"37. IN VIVO FUNCTIONAL GENOMIC SCREEN TO IDENTIFY NOVEL DRIVERS OF LUNG-TO-BRAIN METASTASIS","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Brain metastasis; Metastasis; Lung cancer; Primary tumor; Cancer research; In vivo; Medicine; Lung; Cas9; Cancer; Biology; Pathology; Gene; Internal medicine; Genetics","score_opus":0.01588293592738044,"score_gpt":0.32820188521847377,"score_spread":0.31231894929109333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047501588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9345261,0.000717754,0.060632717,0.0027992586,0.0003708644,0.00032245976,0.00009893025,0.00001584974,0.0005160867],"genre_scores_gemma":[0.99072677,0.00010785387,0.005138293,0.0037291173,0.00019225561,0.00002956744,0.000019464174,0.000021059086,0.00003562307],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989882,0.00003734724,0.00024260394,0.0004064792,0.00010216042,0.00022318972],"domain_scores_gemma":[0.99953467,0.00005916406,0.000053461157,0.0001589103,0.000046252724,0.00014753021],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099756486,0.0001411148,0.00022176652,0.00007079352,0.000027791144,0.000005682676,0.00020112818,0.0000874133,0.000057273177],"category_scores_gemma":[0.0002579854,0.0001550516,0.000070937094,0.00020534884,0.00004363365,0.000006598294,0.00016829275,0.000100068246,0.0000110587025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016545902,0.000033233864,0.0034712313,0.000017963683,0.000027221971,0.00000627111,0.000095660565,0.038252797,0.95263183,0.000030145498,0.0032931634,0.0019750125],"study_design_scores_gemma":[0.0010011715,0.0010974953,0.018200707,0.0000075542002,0.00002851824,0.000012778641,0.00014123888,0.0002824261,0.69768757,0.000013827774,0.28129175,0.0002349681],"about_ca_topic_score_codex":0.0000070013916,"about_ca_topic_score_gemma":0.00009067516,"teacher_disagreement_score":0.27799857,"about_ca_system_score_codex":0.000020005818,"about_ca_system_score_gemma":0.000059634654,"threshold_uncertainty_score":0.6322821},"labels":[],"label_agreement":null},{"id":"W3047613394","doi":"10.1016/j.yexcr.2020.112215","title":"Manipulating the Mediator complex to induce naïve pluripotency","year":2020,"lang":"en","type":"review","venue":"Experimental Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Research Council; Generalitat de Catalunya; European Social Fund; European Regional Development Fund; Bruyère Research Institute","keywords":"Biology; Mediator; Cell biology; Induced pluripotent stem cell; Kinase; Enhancer; MAPK/ERK pathway; Embryonic stem cell; Genetics; Transcription factor; Gene","score_opus":0.15850833660377495,"score_gpt":0.4897245871732981,"score_spread":0.33121625056952314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047613394","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035138425,0.99414694,0.00009947472,0.000064767104,0.0001886333,0.0010375221,0.00002187587,0.000014871266,0.0040745363],"genre_scores_gemma":[0.012213733,0.9840937,0.00059078255,0.00007602685,0.0013080683,0.00038172796,0.0002283588,0.00012286947,0.0009847041],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976672,0.00025153434,0.00035537605,0.0006341661,0.0005358965,0.0005558175],"domain_scores_gemma":[0.99896145,0.00006743628,0.00005296673,0.00057993876,0.000057377358,0.00028081436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042168822,0.00032868338,0.0004797485,0.00009318331,0.00022194498,0.00008138965,0.00081679324,0.00022732894,0.00013989679],"category_scores_gemma":[0.00008165932,0.00024507398,0.0002443288,0.00034244364,0.00007753106,0.0000016733707,0.0010556953,0.0005783168,0.00030959703],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040605908,0.0002096176,0.000003938217,0.0038462053,0.00021276977,0.00008346441,0.0010827911,0.000031733405,0.41564524,0.000069959846,0.048201345,0.5305723],"study_design_scores_gemma":[0.00009240701,0.0002454723,0.0000016322327,0.00023101468,0.000014861748,0.000013461885,0.00039413897,0.000013715148,0.06507502,9.42122e-7,0.9336654,0.00025193437],"about_ca_topic_score_codex":0.000024220748,"about_ca_topic_score_gemma":0.0000033543681,"teacher_disagreement_score":0.8854641,"about_ca_system_score_codex":0.00008613411,"about_ca_system_score_gemma":0.00019702544,"threshold_uncertainty_score":0.99938273},"labels":[],"label_agreement":null},{"id":"W3048408117","doi":"10.3389/fmicb.2020.01969","title":"Generation and Characterization of a Virulent Leptosphaeria maculans Isolate Carrying a Mutated AvrLm7 Gene Using the CRISPR/Cas9 System","year":2020,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Blackleg; Leptosphaeria maculans; Biology; Virulence; Canola; Genotype; Mutant; Genetics; Gene; CRISPR; Plant disease resistance; Pathogen; Brassica; Botany","score_opus":0.01233067464741081,"score_gpt":0.24984394213995842,"score_spread":0.23751326749254761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048408117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7695572,0.0009636421,0.22887218,0.000077101344,0.0003002958,0.00017604006,0.000043441523,0.0000068581376,0.000003254769],"genre_scores_gemma":[0.99516624,0.00015768803,0.004105924,0.00013530202,0.0001434242,0.000008208519,0.00025982084,0.000016966002,0.000006437461],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992419,0.000070184724,0.00024460128,0.0002540691,0.000022161796,0.00016706486],"domain_scores_gemma":[0.9997206,0.0000023421337,0.00008462657,0.0001247235,0.00003422469,0.00003350555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095974385,0.00012476058,0.0001876307,0.00003543913,0.000046772093,0.000010216491,0.00009437408,0.00012934385,0.0000021209855],"category_scores_gemma":[0.000011634329,0.00010845062,0.000037574333,0.00009081102,0.00005709226,0.0000032520759,0.000067053494,0.000068858535,3.4940922e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044121378,0.000005472729,0.0024918723,0.000045916542,0.00004391123,0.0000023167556,0.00033306668,0.001401099,0.9952695,0.0000032060311,0.00007649052,0.00028306],"study_design_scores_gemma":[0.00042151104,0.000082003724,0.0005632154,0.000014764631,0.000028620649,0.00004841986,0.00022874483,0.04006268,0.95743316,5.7343624e-7,0.0009886695,0.00012765394],"about_ca_topic_score_codex":0.000016705362,"about_ca_topic_score_gemma":0.0000051059346,"teacher_disagreement_score":0.22560903,"about_ca_system_score_codex":0.000018741837,"about_ca_system_score_gemma":0.000023418188,"threshold_uncertainty_score":0.4422488},"labels":[],"label_agreement":null},{"id":"W3048429360","doi":"10.1158/1538-7445.pedca19-b09","title":"Abstract B09: Epigenetic changes mediated by H3.3 G34R mutation in a CRISPR-edited pediatric glioblastoma cell line","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Epigenome; CRISPR; Carcinogenesis; Biology; Epigenetics; Histone; Mutation; Genetics; Histone H3; Cancer research; DNA methylation; Methylation; Transcriptome; Epigenomics; Gene; Gene expression","score_opus":0.02845150336223706,"score_gpt":0.3752640989198378,"score_spread":0.34681259555760074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048429360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836632,0.013302314,0.0007586806,0.0015898633,0.00011765213,0.00033703516,0.00009028523,0.000023044122,0.00011790633],"genre_scores_gemma":[0.99341834,0.0050413283,0.000053296364,0.00017512115,0.0008823049,0.00014341556,0.00013097207,0.000042978307,0.00011225582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842745,0.00006736521,0.0002110871,0.00045399443,0.0003473464,0.0004927699],"domain_scores_gemma":[0.9993247,0.000049237373,0.000038956194,0.00019939736,0.00015862688,0.00022909908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027915358,0.00015758535,0.00015035536,0.00015301867,0.000053838492,0.000030777206,0.00024329532,0.00017485007,0.00013599049],"category_scores_gemma":[0.00020500917,0.00016579404,0.00003886247,0.0006343809,0.000047985297,0.0000036722847,0.000111053276,0.00032566275,0.00003970042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001295151,0.00004782984,0.00077744515,0.00016857048,0.00001017107,0.000022070311,0.00021430978,0.001828075,0.9841955,2.8396906e-7,0.011270277,0.0013359861],"study_design_scores_gemma":[0.0009480024,0.00061675254,0.0041826842,0.000015037517,0.000008775186,0.0000011136723,0.00015202675,0.0010028754,0.97940975,0.000004055977,0.013426041,0.00023290211],"about_ca_topic_score_codex":0.00015045471,"about_ca_topic_score_gemma":0.00031266487,"teacher_disagreement_score":0.0097551085,"about_ca_system_score_codex":0.000040523595,"about_ca_system_score_gemma":0.00013716499,"threshold_uncertainty_score":0.67608845},"labels":[],"label_agreement":null},{"id":"W3048528205","doi":"10.7554/elife.54572","title":"Building the vertebrate codex using the gene breaking protein trap library","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Council of Scientific and Industrial Research, India; Mayo Foundation for Medical Education and Research; Roy J. Carver Charitable Trust","keywords":"Vertebrate; Trap (plumbing); Biology; Gene; Computational biology; Gene nomenclature; Genetics; Evolutionary biology; Physics; Zoology; Nomenclature","score_opus":0.015595880121038054,"score_gpt":0.27879168366797624,"score_spread":0.26319580354693817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048528205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9329803,0.0020540478,0.06234486,0.002024793,0.00008999409,0.00023515189,0.000007916554,0.000031482145,0.00023146223],"genre_scores_gemma":[0.99388975,0.000046405436,0.0033366217,0.0019388301,0.00068868266,0.00001176721,0.0000080775,0.000029039365,0.000050798168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999369,0.000036353904,0.00012153531,0.00018900621,0.00010554764,0.00017854272],"domain_scores_gemma":[0.99967265,0.0000071463155,0.000032670083,0.00021653391,0.00001325045,0.000057774003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080711914,0.000109238084,0.00007374292,0.000007725522,0.00013396915,0.000053385986,0.00025654622,0.000053887128,0.00001656875],"category_scores_gemma":[0.000028082064,0.00006934906,0.00006436434,0.00009763885,0.000035883404,0.000004024396,0.00013851325,0.00010515851,0.000004040652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001359165,0.000003973719,0.0001548029,0.0000089147925,0.000026583522,0.0000024229432,0.00010994529,0.0040774606,0.9935557,0.0000829524,0.00082900905,0.0011346443],"study_design_scores_gemma":[0.00014158242,0.00003628422,0.00019855809,0.000009761568,0.000012358564,0.000011386435,0.00005700445,0.014968295,0.940395,0.000010358713,0.04404869,0.00011072457],"about_ca_topic_score_codex":0.0000051776346,"about_ca_topic_score_gemma":0.0000011237388,"teacher_disagreement_score":0.060909484,"about_ca_system_score_codex":0.0000026102011,"about_ca_system_score_gemma":0.00003956396,"threshold_uncertainty_score":0.28279725},"labels":[],"label_agreement":null},{"id":"W3048609924","doi":"10.1016/j.tube.2020.101983","title":"Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9","year":2020,"lang":"en","type":"article","venue":"Tuberculosis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"European Research Council; Medical Research Council; H2020 European Research Council; Cancer Center Amsterdam; University of Arizona Cancer Center","keywords":"Streptococcus thermophilus; CRISPR; Genome editing; Biology; Cas9; Mycobacterium tuberculosis; Streptococcus pyogenes; Trans-activating crRNA; Computational biology; Mycobacterium; Genome; Gene; Genetics; Microbiology; Tuberculosis; Bacteria; Medicine","score_opus":0.013746783205690817,"score_gpt":0.2770399841911862,"score_spread":0.26329320098549536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048609924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953387,0.0010202411,0.0027189602,0.00020434531,0.00015624045,0.00024182136,0.000034410747,0.000025875495,0.00025941542],"genre_scores_gemma":[0.9982019,0.000047822996,0.0006433079,0.0003034693,0.0006903173,0.000019680643,0.00004548782,0.000041159812,0.000006825869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998775,0.000042413696,0.0002768053,0.00042974958,0.00012443119,0.00035160859],"domain_scores_gemma":[0.99951684,0.00000761501,0.000049072547,0.00025419917,0.000034277902,0.00013796263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116927215,0.00020599831,0.00019112379,0.000044976394,0.00005159384,0.00002686429,0.00016820336,0.00012273721,0.00007885591],"category_scores_gemma":[0.00006146458,0.00021529036,0.000116331576,0.0001839182,0.00002538805,0.000001863281,0.00015064295,0.000118857075,0.00001899325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017786515,0.000026067719,0.0027950637,0.000035421574,0.000029836834,0.000011837561,0.00023838987,0.03628234,0.9597568,0.0000035216187,0.000028349617,0.0007745755],"study_design_scores_gemma":[0.0028261843,0.000600391,0.13971359,0.00012177931,0.00020043054,0.00007017946,0.0011076431,0.12010121,0.7256137,0.000020815221,0.007791175,0.0018329115],"about_ca_topic_score_codex":0.000024203468,"about_ca_topic_score_gemma":0.000009880332,"teacher_disagreement_score":0.23414312,"about_ca_system_score_codex":0.00002926131,"about_ca_system_score_gemma":0.000030620275,"threshold_uncertainty_score":0.8779286},"labels":[],"label_agreement":null},{"id":"W3048710693","doi":"10.1186/s12302-020-00361-2","title":"Broadening the GMO risk assessment in the EU for genome editing technologies in agriculture","year":2020,"lang":"en","type":"article","venue":"Environmental Sciences Europe","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Stiftung Mercator; Bundesamt für Naturschutz; Stiftung Mercator Schweiz; European Commission; European Food Safety Authority","keywords":"Genome editing; Genome; Biology; Unintended consequences; CRISPR; Computational biology; Genomics; Biotechnology; Genetics; Evolutionary biology; Gene; Political science","score_opus":0.008167712561241212,"score_gpt":0.2569057181720682,"score_spread":0.24873800561082698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048710693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990952,0.001189929,0.0022155757,0.0044037793,0.000053829262,0.00031643795,0.000014563671,0.000011243505,0.00084260694],"genre_scores_gemma":[0.9983697,0.00032433524,0.00086866453,0.000272837,0.00010707117,0.00002691875,0.000009681321,0.000004678311,0.000016115391],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99933624,0.000041798306,0.00010534259,0.00022786498,0.0001159516,0.00017277223],"domain_scores_gemma":[0.9998374,0.0000196019,0.000035475427,0.00009287205,0.0000013141458,0.000013365788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029986756,0.00007910155,0.000050889234,0.000011412333,0.00012870277,0.000035819037,0.00040088873,0.00003197363,0.000003528835],"category_scores_gemma":[0.000057725632,0.000043170538,0.000026555444,0.00014823093,0.00013279606,0.000004529775,0.00015441935,0.00013347904,0.0000024055485],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004945291,0.00003259124,0.036250822,0.0000060248994,0.0000058862834,0.0000044438707,0.00084449764,0.02864947,0.9295348,0.000053419288,0.0003868186,0.004226287],"study_design_scores_gemma":[0.0008478782,0.00096889917,0.52009135,0.000020271398,0.000022357995,0.000026729094,0.029304707,0.005425722,0.11409631,0.00006202628,0.3286173,0.0005164122],"about_ca_topic_score_codex":0.0000050261565,"about_ca_topic_score_gemma":0.000012028206,"teacher_disagreement_score":0.8154385,"about_ca_system_score_codex":0.000008854333,"about_ca_system_score_gemma":0.0000058496016,"threshold_uncertainty_score":0.17604434},"labels":[],"label_agreement":null},{"id":"W3049240154","doi":"10.3791/61124","title":"High-Resolution Mapping of Protein-DNA Interactions in Mouse Stem Cell-Derived Neurons using Chromatin Immunoprecipitation-Exonuclease (ChIP-Exo)","year":2020,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chromatin immunoprecipitation; Exonuclease; Exonuclease III; ChIP-sequencing; Immunoprecipitation; Biology; ChIP-on-chip; DNA; Chromatin; Genomic library; Molecular biology; DNA sequencing; Computational biology; Genetics; Gene; Gene expression; DNA polymerase; Chromatin remodeling; Promoter; Escherichia coli","score_opus":0.030627185267893733,"score_gpt":0.3729726182878657,"score_spread":0.342345433019972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3049240154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97739035,0.00059935456,0.02159478,0.000042749656,0.0001498827,0.00019293623,0.0000072729745,0.0000053901276,0.000017260183],"genre_scores_gemma":[0.9899743,0.000041852774,0.009763306,0.000044927398,0.00010771816,0.000006447088,0.000009340813,0.000025670895,0.00002643009],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988392,0.00009252531,0.0006048704,0.00014673042,0.00016488052,0.00015180759],"domain_scores_gemma":[0.99929875,0.000009537881,0.0003819179,0.000121439785,0.00009557224,0.000092778646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010275976,0.00013870336,0.00023692983,0.0001070886,0.000040558083,0.000018531904,0.00014046016,0.000050762057,0.000020425063],"category_scores_gemma":[0.0000390475,0.00014457638,0.00011284712,0.00012143603,0.00002364778,0.000018398885,0.000067130386,0.00012180981,0.0000013837291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021563884,0.00015406447,0.00007971738,0.000041394873,0.00005025155,0.0000049142327,0.0013465604,0.0054928605,0.99239504,0.0000035219095,0.00003650594,0.0001795304],"study_design_scores_gemma":[0.0017181238,0.00028093127,0.0005035089,0.000086029555,0.000013667635,0.000009592999,0.001285758,0.0035563917,0.9922131,0.000002001903,0.00020796864,0.00012294078],"about_ca_topic_score_codex":0.000028774884,"about_ca_topic_score_gemma":0.0000015750787,"teacher_disagreement_score":0.012583933,"about_ca_system_score_codex":0.00003912411,"about_ca_system_score_gemma":0.000057781286,"threshold_uncertainty_score":0.58956534},"labels":[],"label_agreement":null},{"id":"W3049383037","doi":"10.1155/2020/2907623","title":"The Development and Application of a Base Editor in Biomedicine","year":2020,"lang":"en","type":"review","venue":"BioMed Research International","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; School of Medicine, New York University; York University","keywords":"CRISPR; Point mutation; Computational biology; Flexibility (engineering); Genome editing; Computer science; Biomedicine; Base (topology); Cas9; Mutation; Biology; Bioinformatics; Gene; Genetics; Mathematics","score_opus":0.04343680734732257,"score_gpt":0.45234245792623007,"score_spread":0.4089056505789075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3049383037","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003685058,0.99687964,0.0015805908,0.00026100993,0.00073926896,0.00035069147,0.000033187498,0.0000025805207,0.00011615724],"genre_scores_gemma":[0.0003560558,0.9963661,0.00055821723,0.0000033740841,0.0020271672,0.00018452459,0.00034932303,0.0000142078425,0.0001410335],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989291,0.000058540023,0.00031376735,0.00023164206,0.00032094095,0.00014603576],"domain_scores_gemma":[0.9995496,0.00008065609,0.000059024544,0.00014671122,0.00010105078,0.00006294239],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006919899,0.000098785735,0.00019005396,0.00019494617,0.000036667043,0.000015104819,0.00031717893,0.00010932329,0.0000027548856],"category_scores_gemma":[0.00023947615,0.000067398745,0.00004126266,0.00022419114,0.00013104483,9.534833e-7,0.00023849455,0.00015355082,0.000006069458],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010897234,0.000018667208,0.000007625257,0.0006776991,0.000066932276,0.000001475381,0.000025466436,3.0918773e-7,0.0018025786,0.000034545337,0.0036911145,0.9936627],"study_design_scores_gemma":[0.000121635516,0.00003677205,0.000021272452,0.00035231654,0.0000047822446,0.000003995589,0.000024759554,0.00006891971,0.0007279157,0.0000049624427,0.99857134,0.00006132087],"about_ca_topic_score_codex":0.000007784311,"about_ca_topic_score_gemma":0.000020241027,"teacher_disagreement_score":0.99488026,"about_ca_system_score_codex":0.000041195486,"about_ca_system_score_gemma":0.0002193527,"threshold_uncertainty_score":0.2748441},"labels":[],"label_agreement":null},{"id":"W3051852199","doi":"10.1016/j.molp.2020.08.008","title":"Genome Editing: Small-Size CasΦ Is Shining","year":2020,"lang":"en","type":"article","venue":"Molecular Plant","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Global Institute for Water Security; University of Saskatchewan","funders":"","keywords":"Biology; Genome size; Genome; Evolutionary biology; Computational biology; Genetics; Gene","score_opus":0.010981638399709268,"score_gpt":0.241952259850953,"score_spread":0.23097062145124375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3051852199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9534255,0.0016593864,0.041513126,0.0010867126,0.00015402291,0.00013990806,0.000078357945,0.00004392969,0.0018990152],"genre_scores_gemma":[0.9945027,0.000048314847,0.001830086,0.0028698973,0.00045258657,0.000009513315,0.00014499074,0.000036838133,0.00010503943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906594,0.000018724762,0.00016350113,0.00035949858,0.000115422146,0.00027689897],"domain_scores_gemma":[0.99953634,0.000007264111,0.000036159265,0.00022296372,0.000024932511,0.00017235274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006524566,0.00016975179,0.00013569166,0.000015071706,0.000045396635,0.000030271989,0.00019338261,0.00010625518,0.00005165137],"category_scores_gemma":[0.000095119874,0.00017971962,0.00009493459,0.00006787923,0.000019094094,0.000001197218,0.00012755064,0.00011064298,0.000030359619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017198578,0.000008651614,0.00020338292,0.000024035988,0.00004912914,0.00010197354,0.00023538304,0.00070739444,0.9974522,0.000017494813,0.0009295255,0.00025362725],"study_design_scores_gemma":[0.00036469306,0.00016498017,0.0008159995,0.000009523301,0.000025186268,0.000058609752,0.00010559094,0.0006259412,0.930726,0.000009191542,0.066810004,0.0002842808],"about_ca_topic_score_codex":0.000008694877,"about_ca_topic_score_gemma":0.0000028995,"teacher_disagreement_score":0.0667262,"about_ca_system_score_codex":0.0000057487246,"about_ca_system_score_gemma":0.000027200427,"threshold_uncertainty_score":0.73287535},"labels":[],"label_agreement":null},{"id":"W3062204540","doi":"10.26685/urncst.188","title":"Using CRISPR-X for Optimization of Antibodies Towards A30P α-synuclein Oligomers in Immunotherapy of Parkinson’s Disease","year":2020,"lang":"en","type":"article","venue":"Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"CRISPR; Parkinson's disease; Immunotherapy; Antibody; Disease; Computational biology; Virology; Medicine; Biology; Immunology; Genetics; Immune system; Gene; Pathology","score_opus":0.06278434175943126,"score_gpt":0.44183060757624265,"score_spread":0.3790462658168114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3062204540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832917,0.005570284,0.0031593796,0.0077272616,0.00006292548,0.00016640263,0.0000041146063,0.0000033260285,0.000014602999],"genre_scores_gemma":[0.9796647,0.015875457,0.0043688463,0.00003841968,0.000038821647,0.0000023756966,0.0000012709414,0.0000057390134,0.0000043884334],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99870783,0.000059661525,0.0004051709,0.00027283313,0.00024797345,0.00030654995],"domain_scores_gemma":[0.9993394,0.0000582611,0.00008837875,0.00009643412,0.00028872673,0.00012879717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015633747,0.0000851972,0.00021117213,0.00031255133,0.00011042493,0.000024908732,0.00024502803,0.000118942124,0.0000012747804],"category_scores_gemma":[0.0010040938,0.000067640416,0.00004600497,0.00075814134,0.0011339916,0.00001834356,0.00016047714,0.00037587294,5.6764964e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011315141,0.00026342442,0.21152475,0.00021496862,0.00008615552,0.000028497916,0.00011349907,0.0063591544,0.6789797,0.0010531854,0.00011169051,0.100133464],"study_design_scores_gemma":[0.012057422,0.0060323924,0.15655655,0.0008822593,0.00006987742,0.00015807559,0.0031872557,0.5010114,0.28079483,0.033645663,0.0044926642,0.0011116586],"about_ca_topic_score_codex":0.000017036207,"about_ca_topic_score_gemma":0.000011591283,"teacher_disagreement_score":0.4946522,"about_ca_system_score_codex":0.000019565015,"about_ca_system_score_gemma":0.00023882059,"threshold_uncertainty_score":0.41782394},"labels":[],"label_agreement":null},{"id":"W3080077183","doi":"10.1089/crispr.2020.29100.kma","title":"Retrons: Complementing CRISPR in Phage Defense","year":2020,"lang":"en","type":"letter","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Library science; Computer science; Biology; Genetics; Gene","score_opus":0.019827472434813684,"score_gpt":0.3156452896545455,"score_spread":0.2958178172197318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080077183","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019099452,0.02017667,0.04414999,0.9094894,0.002856779,0.0008053694,0.00012426212,0.000061517814,0.0032365557],"genre_scores_gemma":[0.29641163,0.0025527126,0.0020522946,0.67184985,0.02473368,0.000038213697,0.00041384881,0.00027749475,0.0016702743],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978823,0.00021841857,0.00055416895,0.00037834852,0.00033336986,0.0006333579],"domain_scores_gemma":[0.9991055,0.000042440854,0.00022189322,0.00046220337,0.00007433131,0.00009360742],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004665807,0.00036871035,0.00034412704,0.000099964105,0.00021648796,0.0001422745,0.0007080343,0.00032883135,0.00015365033],"category_scores_gemma":[0.00015894554,0.00029194666,0.0002679787,0.00013187493,0.00007418844,0.000003945873,0.0002599021,0.0025611683,0.00003461561],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018539118,0.000010598596,0.00022929996,0.000055947636,0.00010367193,0.00047465865,0.00015348785,0.00014721975,0.015488105,0.000003703418,0.9827074,0.00060738006],"study_design_scores_gemma":[0.0005959853,0.0001310922,0.00013623362,0.00008363804,0.0000848792,0.0005931459,0.00023581393,0.0001445423,0.012468559,0.00016225725,0.98497397,0.0003898951],"about_ca_topic_score_codex":0.000016555576,"about_ca_topic_score_gemma":0.000018924193,"teacher_disagreement_score":0.27731216,"about_ca_system_score_codex":0.000042354044,"about_ca_system_score_gemma":0.00010018527,"threshold_uncertainty_score":0.99995327},"labels":[],"label_agreement":null},{"id":"W3080409390","doi":"10.1101/2020.08.20.259762","title":"Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Advanced Research Projects Agency; National Institutes of Health; York University; Sidney Kimmel Foundation; Melanoma Research Alliance","keywords":"CRISPR; Biology; RNA; Guide RNA; Computational biology; Cas9; Gene; Non-coding RNA; RNA editing; Genetics","score_opus":0.016210145933828354,"score_gpt":0.24867334287718681,"score_spread":0.23246319694335846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080409390","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3394013,0.0023632562,0.6561422,0.00023342483,0.00041182432,0.0008756915,0.00044968803,0.00011551096,0.0000071094546],"genre_scores_gemma":[0.91044927,0.000714921,0.08745951,0.00044072882,0.0004701606,0.0002319334,0.00000341045,0.0002100644,0.000019972282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99749583,0.000056694673,0.0004983875,0.0011791056,0.00020170472,0.0005682924],"domain_scores_gemma":[0.9983665,0.00002899264,0.00015697845,0.00083020044,0.000256121,0.00036125028],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034967196,0.0006243759,0.00050926814,0.00009503135,0.00013217637,0.00012956963,0.0004383431,0.00064342923,0.000005273772],"category_scores_gemma":[0.0002369895,0.0007125284,0.00020923073,0.000115827635,0.000080585174,0.000007530166,0.00031843732,0.000347901,0.000004629536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006282665,0.00003266509,0.00007554757,0.00025835415,0.00016095357,0.000014319339,0.000017642811,0.0068874503,0.9909256,0.00009183052,0.0014678137,0.000005010654],"study_design_scores_gemma":[0.0007128699,0.00016984258,0.00060379494,0.000068773785,0.000187947,5.040105e-8,0.000003897589,0.014879096,0.9764991,0.000011127873,0.006019076,0.00084445975],"about_ca_topic_score_codex":0.000009087911,"about_ca_topic_score_gemma":0.0000015030745,"teacher_disagreement_score":0.571048,"about_ca_system_score_codex":0.000057440207,"about_ca_system_score_gemma":0.00043629037,"threshold_uncertainty_score":0.9995326},"labels":[],"label_agreement":null},{"id":"W3081752008","doi":"10.1158/1557-3265.ovca19-b17","title":"Abstract B17: Modeling ovarian cancer in mice using in vivo electroporation and CRISPR-mediated genome editing","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Centre for Applied Research in Cancer Control; Spinal Cord Injury BC; McGill University","funders":"","keywords":"Ovarian cancer; Biology; Cancer research; Metastasis; Cancer; Fallopian tube; Serous fluid; Ovarian carcinoma; Electroporation; Carcinogenesis; Pathology; Medicine; Gene; Genetics","score_opus":0.129065900603426,"score_gpt":0.49461079838572136,"score_spread":0.3655448977822954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081752008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926093,0.003324732,0.0026161603,0.0010567917,0.000075508535,0.00021404745,0.00002260952,0.000006851613,0.00007396871],"genre_scores_gemma":[0.99568784,0.0028299885,0.0002474634,0.00017791521,0.000973967,0.000033011187,0.000017898217,0.000023795716,0.000008132917],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9984297,0.00010081154,0.00042763897,0.0004513911,0.0001922944,0.00039815996],"domain_scores_gemma":[0.99953324,0.000054915217,0.000038208535,0.00011014557,0.00011024766,0.00015322177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009850214,0.0001052888,0.00018149572,0.00007441986,0.000049368336,0.000033372085,0.00013368524,0.00018141513,0.000058394115],"category_scores_gemma":[0.00048002176,0.00011300096,0.000035103407,0.00029150533,0.000059160717,0.0000079003985,0.000116221316,0.0005489114,0.0000013743551],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017223932,0.00002753756,0.014455846,0.00006721847,0.000015096911,0.000011837434,0.00013410748,0.06200479,0.9214001,0.0000033231127,0.0000884739,0.0016194133],"study_design_scores_gemma":[0.0031609868,0.00042173325,0.040668048,0.00017352657,0.000016935319,0.0000032410978,0.000670376,0.8490096,0.10186243,0.00008203398,0.0033374506,0.00059363653],"about_ca_topic_score_codex":0.0014521668,"about_ca_topic_score_gemma":0.0022930647,"teacher_disagreement_score":0.8195377,"about_ca_system_score_codex":0.00005979832,"about_ca_system_score_gemma":0.000248273,"threshold_uncertainty_score":0.46080455},"labels":[],"label_agreement":null},{"id":"W3082114801","doi":"10.1002/lipd.12249","title":"The Potential of Genome Editing for Improving Seed Oil Content and Fatty Acid Composition in Oilseed Crops","year":2020,"lang":"en","type":"review","venue":"Lipids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; University of Alberta; University of Lethbridge","funders":"Agriculture and Agri-Food Canada; Beef Cattle Research Council","keywords":"Genome editing; Biotechnology; Commercialization; Context (archaeology); Canola; Biology; CRISPR; Business; Agronomy; Marketing; Gene; Genetics","score_opus":0.014519040350595572,"score_gpt":0.2839792944358921,"score_spread":0.2694602540852965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082114801","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00095730304,0.98650974,0.011777592,0.000033956032,0.00036176137,0.00025258696,0.000069033085,0.0000063214075,0.000031698593],"genre_scores_gemma":[0.01581645,0.9815817,0.00089854613,0.000017364811,0.0012025563,0.000084716354,0.0003133809,0.00003779248,0.000047528363],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990977,0.000034694567,0.0003644512,0.0002556829,0.00006387061,0.0001835697],"domain_scores_gemma":[0.9995911,0.000020837651,0.00014336946,0.00015712195,0.000041188003,0.000046347188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015163669,0.00018584922,0.00043404772,0.000028375021,0.00006046902,0.000027461105,0.00013666209,0.00017008216,5.098954e-7],"category_scores_gemma":[0.000041797935,0.0001454184,0.00017650776,0.000049971204,0.00004198288,0.0000014928203,0.00011819456,0.00011900451,3.2328524e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023185776,0.000011097615,0.0000087411245,0.0056059924,0.00006982728,0.000001295616,0.000021957538,0.000021697526,0.3117837,0.000008028193,0.0000056501026,0.6824388],"study_design_scores_gemma":[0.0015761125,0.00056362944,0.00037917856,0.0019330072,0.00064328185,0.000073039446,0.00018537704,0.0011199928,0.029186063,0.000007826455,0.9635656,0.00076689816],"about_ca_topic_score_codex":0.00000886474,"about_ca_topic_score_gemma":0.0000082543875,"teacher_disagreement_score":0.9635599,"about_ca_system_score_codex":0.000013917159,"about_ca_system_score_gemma":0.000043281834,"threshold_uncertainty_score":0.592999},"labels":[],"label_agreement":null},{"id":"W3082361699","doi":"10.1186/s13059-020-02146-5","title":"Fine-tuning sugar content in strawberry","year":2020,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Biology; Fragaria; Genetics; Mutant; Allele; Asexual reproduction; Open reading frame; Sugar; Gene; Phenotype; Quantitative trait locus; Food science","score_opus":0.027638195917154815,"score_gpt":0.30070158833806876,"score_spread":0.27306339242091393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082361699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882808,0.0027093368,0.007045033,0.0006338292,0.00011471764,0.000110766254,0.000018197848,0.000015927955,0.0010714342],"genre_scores_gemma":[0.99836564,0.00009230579,0.00051824347,0.0005213977,0.0002616072,0.000009462803,0.00011094118,0.000013221389,0.00010718576],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992928,0.000024784278,0.00015807169,0.00026840306,0.000025148991,0.00023081318],"domain_scores_gemma":[0.9997404,0.0000057899824,0.000023180623,0.0001325201,0.000017701226,0.000080360114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006314145,0.00010677711,0.00012961701,0.000025396897,0.000017631675,0.0000050768313,0.00013698568,0.00011774105,0.000053076605],"category_scores_gemma":[0.000047533023,0.00010582632,0.000045092675,0.000057751924,0.000033406206,6.4764646e-7,0.00009100302,0.00008221649,0.000024144714],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026181084,0.000008701358,0.008259162,0.000008959442,0.000015319507,0.0000044675726,0.000077087745,0.00039802428,0.9897821,0.00008646078,0.00011241215,0.0012211095],"study_design_scores_gemma":[0.0027736258,0.0017571568,0.1297252,0.000015207308,0.000024771214,0.000038878396,0.00048423075,0.00075840147,0.29527986,0.00012521492,0.568013,0.0010044496],"about_ca_topic_score_codex":0.000023066928,"about_ca_topic_score_gemma":0.000053172127,"teacher_disagreement_score":0.69450223,"about_ca_system_score_codex":0.000006747149,"about_ca_system_score_gemma":0.00002186088,"threshold_uncertainty_score":0.43154722},"labels":[],"label_agreement":null},{"id":"W3082386323","doi":"10.1158/1538-7445.am2020-549","title":"Abstract 549: Genome-wide CRISPR-Cas9 screen and RNAseq analysis identify new candidate synthetic lethality partners to PARP inhibitor in triple-negative breast cancer","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Synthetic lethality; Olaparib; Triple-negative breast cancer; Biology; PARP inhibitor; Cancer research; Genome editing; Cancer; Breast cancer; Genetics; DNA repair; Gene; Poly ADP ribose polymerase; Polymerase","score_opus":0.04823621442026489,"score_gpt":0.4320396808816556,"score_spread":0.38380346646139074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082386323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99106455,0.0026648026,0.0012468402,0.0039640567,0.00006185884,0.00046200852,0.00038222966,0.000012094719,0.00014156154],"genre_scores_gemma":[0.99749523,0.0012431456,0.00009441931,0.0002854383,0.00040820078,0.00012710133,0.0000461225,0.000031357908,0.00026899253],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99789536,0.000112329835,0.00030433264,0.00072392105,0.00037153697,0.00059249037],"domain_scores_gemma":[0.9988135,0.00005438091,0.00004423584,0.0003339775,0.00015576936,0.00059809966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048317423,0.00020693269,0.0003170636,0.00021133144,0.00009410553,0.00009034987,0.00027842686,0.00012765522,0.00030008916],"category_scores_gemma":[0.00023392717,0.00020675569,0.000100551384,0.000955488,0.00011133307,0.000010323782,0.0002531791,0.00033564624,0.000011452292],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009806528,0.00006365177,0.07046457,0.0002016652,0.00080783246,0.00006194819,0.001758667,0.017722929,0.8873219,0.000005843278,0.011233308,0.009377063],"study_design_scores_gemma":[0.0014342411,0.00017414113,0.6655864,0.000094790616,0.00014250453,0.0000035713751,0.00075607013,0.00031953523,0.3212069,0.000026159752,0.009681554,0.00057409273],"about_ca_topic_score_codex":0.015090797,"about_ca_topic_score_gemma":0.01166281,"teacher_disagreement_score":0.59512186,"about_ca_system_score_codex":0.00011512387,"about_ca_system_score_gemma":0.0003882347,"threshold_uncertainty_score":0.9914678},"labels":[],"label_agreement":null},{"id":"W3082579484","doi":"10.1080/09168451.2020.1809988","title":"Detection of 30 bp DNA fragments with a sensitive modified Southern blot analysis","year":2020,"lang":"en","type":"article","venue":"Bioscience Biotechnology and Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cabinet Office, Government of Japan; Swine Innovation Porc","keywords":"Southern blot; Biology; Recombinant DNA; Gene; Molecular biology; Western blot; Genetics; Northern blot; DNA; Dot blot; Complementary DNA","score_opus":0.00518432930654945,"score_gpt":0.2268489459756086,"score_spread":0.22166461666905915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082579484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9673544,0.00018227748,0.03193698,0.00031712107,0.000014829307,0.00006841122,0.00002961452,0.000029609635,0.000066742636],"genre_scores_gemma":[0.99915606,0.00006801912,0.0005629639,0.000114235794,0.00003262694,0.0000041311127,0.00001385087,0.00000697156,0.000041168867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991245,0.000008836771,0.00014644282,0.0004426328,0.000098105265,0.00017947596],"domain_scores_gemma":[0.9995846,0.000004316821,0.00007636685,0.0002129989,0.00004287928,0.00007883546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006723998,0.00014122803,0.00016030387,0.000055973924,0.0000623404,0.000008696729,0.00014704694,0.00030698808,0.0000031572642],"category_scores_gemma":[0.00005022189,0.000120405864,0.00005304287,0.0004587724,0.0003831923,0.000002108296,0.00010261,0.000093742994,0.0000012169008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005218792,0.000017965513,0.00083339517,0.000021413543,0.000103972394,0.000002256959,0.000051297637,0.000060599923,0.9972663,0.000005103836,0.0000027920862,0.0015827065],"study_design_scores_gemma":[0.00023797296,0.00024410545,0.00064695574,0.000006399752,0.00009196467,0.000010892157,0.00036839728,0.0010419925,0.99705523,0.0000038341805,0.00013920722,0.00015304258],"about_ca_topic_score_codex":0.0000073921406,"about_ca_topic_score_gemma":0.0000047506337,"teacher_disagreement_score":0.03180162,"about_ca_system_score_codex":0.000005302702,"about_ca_system_score_gemma":0.000028131037,"threshold_uncertainty_score":0.49100086},"labels":[],"label_agreement":null},{"id":"W3082721106","doi":"10.31542/muse.v4i1.1866","title":"CRISPR: A Revolutionary Technique... For Humans?","year":2020,"lang":"en","type":"article","venue":"MacEwan University Student eJournal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"MacEwan University","funders":"","keywords":"CRISPR; Genome editing; Germline; Computational biology; Cas9; Biology; Organism; Genetics; Computer science; Gene","score_opus":0.012080549443723958,"score_gpt":0.2920798737293493,"score_spread":0.27999932428562535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082721106","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12961966,0.0007003538,0.8653604,0.0015151569,0.00012493391,0.00047331402,0.000046741763,0.00003376578,0.0021256802],"genre_scores_gemma":[0.99272597,0.0001919896,0.0055959136,0.0002693906,0.0003294223,0.0000022457689,0.000024574567,0.000013935539,0.00084658747],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999423,0.000018026703,0.00008676959,0.00020145554,0.000107049884,0.00016368415],"domain_scores_gemma":[0.9996727,0.0000045047227,0.00003568178,0.000104184764,0.000060098846,0.00012283938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007598253,0.00009684887,0.0000904344,0.00003279043,0.00014942916,0.0000090346,0.00023331559,0.0000639673,0.00003184079],"category_scores_gemma":[0.000015364822,0.00011234927,0.0001123508,0.00006215134,0.000026118807,0.0000032172675,0.00012937938,0.00008887366,0.0000039119805],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029013303,0.000086118656,0.014307472,0.000050224033,0.0001699509,0.000039249186,0.00040375532,0.0009889088,0.92655635,0.00025174147,0.056132752,0.0007233433],"study_design_scores_gemma":[0.0018991863,0.00092748244,0.022588978,0.00002391706,0.000101346624,0.00004556264,0.0020695922,0.00017601017,0.14916143,0.00003544381,0.8225226,0.000448487],"about_ca_topic_score_codex":0.0000023110995,"about_ca_topic_score_gemma":0.0000050151125,"teacher_disagreement_score":0.8631063,"about_ca_system_score_codex":0.000023891265,"about_ca_system_score_gemma":0.0000313042,"threshold_uncertainty_score":0.45814702},"labels":[],"label_agreement":null},{"id":"W3082980940","doi":"10.1101/2020.08.27.270819","title":"Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Agency for Science, Technology and Research; Graduiertenakademie, Technische Universität Dresden; Massachusetts Consortium on Pathogen Readiness; Qatar Biomedical Research Institute, Hamad Bin Khalifa University; Fundação de Amparo à Pesquisa do Estado de São Paulo; American Heart Association","keywords":"CRISPR; Cas9; Transcriptome; Genome editing; Cytotoxicity; Computational biology; Genome; Subgenomic mRNA; Biology; Genetics; Gene; Gene expression","score_opus":0.01814431146661606,"score_gpt":0.24351288087731782,"score_spread":0.22536856941070177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082980940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71419305,0.002669146,0.28205237,0.00010825391,0.00020983297,0.00043639404,0.00024967722,0.00006969244,0.000011579205],"genre_scores_gemma":[0.9734934,0.0015305735,0.024228204,0.00021572047,0.00035332944,0.0000530081,0.00000547492,0.00011880977,0.0000014628537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776816,0.00007865641,0.0005604197,0.0009598568,0.00024351303,0.00038940238],"domain_scores_gemma":[0.9984271,0.000023739272,0.00028449777,0.00083419395,0.00023845295,0.00019201581],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030297547,0.0004986534,0.00052643573,0.000085126136,0.00009244173,0.000072151524,0.00037893708,0.00058308145,0.0000073288406],"category_scores_gemma":[0.00021584172,0.00059254817,0.00018525992,0.00018395673,0.00011509648,0.000013025777,0.00040662257,0.0004524077,0.0000025523204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059222417,0.000038054426,0.0023665635,0.00047509323,0.00015965158,0.000008701872,0.000032481712,0.0006843269,0.9960137,0.000070455295,0.000088215274,0.0000035410012],"study_design_scores_gemma":[0.0004671486,0.00011535497,0.05120815,0.00012551186,0.000109871246,4.4137835e-8,0.000009216247,0.0005368957,0.9437578,0.0000039060783,0.0030871334,0.0005789864],"about_ca_topic_score_codex":0.000025968044,"about_ca_topic_score_gemma":0.0000027260792,"teacher_disagreement_score":0.25930035,"about_ca_system_score_codex":0.000035922734,"about_ca_system_score_gemma":0.00019515208,"threshold_uncertainty_score":0.99965256},"labels":[],"label_agreement":null},{"id":"W3084360737","doi":"10.1101/2020.07.13.20153122","title":"Replication assessment of <i>NUS1</i> variants in Parkinson’s Disease","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Nonsynonymous substitution; Genome-wide association study; Genetic association; Exome; Disease; Genetics; Biology; Population; Exome sequencing; Medicine; Gene; Genome; Mutation; Single-nucleotide polymorphism; Genotype; Internal medicine","score_opus":0.016311537217586207,"score_gpt":0.32904980917207494,"score_spread":0.3127382719544887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084360737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705753,0.0010034598,0.026644526,0.00045976226,0.0002540538,0.00031386002,0.00007237957,0.000013657825,0.00066301436],"genre_scores_gemma":[0.99672353,0.00052003766,0.0020855486,0.000084694926,0.00014882814,0.00007806976,0.00028877368,0.000023900586,0.000046601137],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99883837,0.000043237713,0.00028680425,0.00057307136,0.00012727693,0.00013125633],"domain_scores_gemma":[0.99884075,0.000006298626,0.00010512725,0.00091099436,0.000036539055,0.00010031175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020516472,0.00015481673,0.00019366996,0.00004059081,0.000009522943,0.00000939654,0.00026454974,0.00013789735,0.000009326954],"category_scores_gemma":[0.000117589305,0.0001682734,0.00008958272,0.00006206254,0.000020006595,7.61594e-7,0.0003716185,0.00017425591,0.0000013765701],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051049687,0.00012410189,0.39450166,0.0004921821,0.00006257893,0.000016576112,0.000053604967,0.009223145,0.59299374,0.00009890944,0.00063771295,0.0017447525],"study_design_scores_gemma":[0.00026615226,0.00004385173,0.92605376,0.00008034414,0.000030088713,9.052265e-7,0.0000073848596,0.004420117,0.052255128,0.00022583995,0.016387196,0.00022922693],"about_ca_topic_score_codex":0.000017445183,"about_ca_topic_score_gemma":0.000011965369,"teacher_disagreement_score":0.5407386,"about_ca_system_score_codex":0.000015002796,"about_ca_system_score_gemma":0.00014363693,"threshold_uncertainty_score":0.686199},"labels":[],"label_agreement":null},{"id":"W3084464175","doi":"10.1007/978-1-0716-0687-2_11","title":"Methods for Measuring CRISPR/Cas9 DNA Cleavage in Cells","year":2020,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Computational biology; Genome editing; DNA; Cleavage (geology); Biology; Genome; Gene; Genetics; Computer science","score_opus":0.03703542128891278,"score_gpt":0.4605061170783004,"score_spread":0.4234706957893876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084464175","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015314253,0.0026867674,0.9804431,0.00032792301,0.00029670066,0.00044913965,0.000009443885,0.000021881733,0.00045077153],"genre_scores_gemma":[0.040510837,0.00011700956,0.95798236,0.001019921,0.00013328371,0.00011950808,0.000031918917,0.000056556913,0.000028577151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973048,0.00093951315,0.0004661179,0.00071624806,0.000050888288,0.00052241073],"domain_scores_gemma":[0.99925,0.0001419931,0.00007130294,0.00036966935,0.00004012257,0.00012694136],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001778368,0.00027185658,0.00041660745,0.00012487065,0.000028758051,0.000013707199,0.00035902456,0.00036293865,0.000009459092],"category_scores_gemma":[0.0010312604,0.0002908978,0.00017545657,0.0002638041,0.000067739,0.00000239731,0.00021443132,0.00022854179,0.0000024681717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007469382,0.00002651742,0.00026713777,0.000052771178,0.000028791246,0.000007713197,0.000105788604,0.0010684344,0.9589188,0.00020637641,0.00007218413,0.039170757],"study_design_scores_gemma":[0.00080804696,0.00028436593,0.00012009361,0.000010532667,0.000014782112,0.0000051989437,0.00006396863,0.0025785535,0.9606327,0.0007595361,0.03440549,0.00031675684],"about_ca_topic_score_codex":0.000017216791,"about_ca_topic_score_gemma":0.000013662922,"teacher_disagreement_score":0.038854,"about_ca_system_score_codex":0.000022840939,"about_ca_system_score_gemma":0.000044325476,"threshold_uncertainty_score":0.99995434},"labels":[],"label_agreement":null},{"id":"W3085196816","doi":"10.1186/s12870-020-02609-8","title":"Establishment of a PEG-mediated protoplast transformation system based on DNA and CRISPR/Cas9 ribonucleoprotein complexes for banana","year":2020,"lang":"en","type":"article","venue":"BMC Plant Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture; Institute of Genetics","funders":"National Natural Science Foundation of China","keywords":"CRISPR; Biology; Cas9; Protoplast; Genome editing; Transformation (genetics); Plasmid; Ribonucleoprotein; Guide RNA; DNA; Mutagenesis; Computational biology; Gene; Genetics; Molecular biology; RNA; Mutation","score_opus":0.015350881008067462,"score_gpt":0.2713733266525655,"score_spread":0.25602244564449805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3085196816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7341444,0.00024169419,0.2614195,0.00032111717,0.00009853816,0.0019285737,0.0016472702,0.000039139457,0.00015977056],"genre_scores_gemma":[0.9969055,0.000011742576,0.0016335984,0.00011793872,0.00007703012,0.00015451993,0.0010850006,0.000011674118,0.0000030058134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992791,0.00003706451,0.00022961273,0.00023384692,0.000049702616,0.00017068537],"domain_scores_gemma":[0.99967587,0.000041879146,0.00006520079,0.00010841601,0.000035033794,0.0000736119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001078681,0.00013195496,0.00019617617,0.000040184146,0.000034429708,0.000007567425,0.000080456695,0.00012319771,0.000003222453],"category_scores_gemma":[0.00006368406,0.00011448607,0.00005147733,0.000046523164,0.000044951863,0.0000020358,0.00001772688,0.000041145115,0.0000011358726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065880653,0.0000306401,0.0011213961,0.00077213004,0.000025649711,6.886685e-7,0.000101362464,0.00069663115,0.9954099,0.00041583262,0.0003080831,0.0004588972],"study_design_scores_gemma":[0.002060116,0.0019530432,0.0011816671,0.000068625726,0.000028286364,0.000010852328,0.00022269614,0.05833271,0.9209997,0.000005702081,0.0149009,0.00023569899],"about_ca_topic_score_codex":0.00001366596,"about_ca_topic_score_gemma":0.00003328259,"teacher_disagreement_score":0.2627611,"about_ca_system_score_codex":0.0000068108407,"about_ca_system_score_gemma":0.000034899374,"threshold_uncertainty_score":0.46686065},"labels":[],"label_agreement":null},{"id":"W3085288672","doi":"10.1186/s12860-020-00308-8","title":"Ommochrome pathway genes kynurenine 3-hydroxylase and cardinal participate in eye pigmentation in Plutella xylostella","year":2020,"lang":"en","type":"article","venue":"BMC Molecular and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Biotechnology and Biological Sciences Research Council; Horizon 2020 Framework Programme; Directorate for Biological Sciences; Horizon 2020; China Scholarship Council; Pirbright Institute; European Commission","keywords":"Plutella; Biology; Gene; Genetics; Kynurenine; Botany; Lepidoptera genitalia; Tryptophan","score_opus":0.011064760572189065,"score_gpt":0.2893395449922487,"score_spread":0.2782747844200596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3085288672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853212,0.00861969,0.0054991054,0.00009084935,0.000042723383,0.00016425744,0.000012037285,0.0000070011597,0.00024308867],"genre_scores_gemma":[0.99827343,0.0005997003,0.000714095,0.00021819433,0.000056698096,0.000014933493,0.000086276326,0.000016292215,0.00002039368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990162,0.00009032818,0.00019650838,0.00040331602,0.00004223252,0.00025138885],"domain_scores_gemma":[0.99971235,0.0000105809395,0.00003281448,0.00012323922,0.000011730726,0.000109303575],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010317713,0.00016520107,0.00019647327,0.000050056253,0.00001922847,0.000011929088,0.00006491519,0.00014513172,0.0000074311565],"category_scores_gemma":[0.000020832458,0.00016756798,0.00003988281,0.00008914222,0.000058786412,0.0000023164678,0.000100787795,0.0000807932,0.000002271855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071809955,0.000019827903,0.023897462,0.000053349788,0.000009029671,0.000022168771,0.00012974048,0.0016616029,0.97197396,0.000023191069,0.000006405343,0.0021314512],"study_design_scores_gemma":[0.0013325523,0.00039179425,0.004471111,0.000009087614,0.000013966723,0.000007083836,0.00011646511,0.0020646183,0.9899418,0.000037755646,0.0013730035,0.0002407883],"about_ca_topic_score_codex":0.00003063343,"about_ca_topic_score_gemma":0.00007414703,"teacher_disagreement_score":0.01942635,"about_ca_system_score_codex":0.000005826402,"about_ca_system_score_gemma":0.000024587614,"threshold_uncertainty_score":0.68332237},"labels":[],"label_agreement":null},{"id":"W3086851723","doi":"10.1007/978-1-0716-0687-2_12","title":"In Vitro Assays for Comparing the Specificity of First- and Next-Generation CRISPR/Cas9 Systems","year":2020,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Computational biology; DNA; Biology; Guide RNA; RNA; Genome editing; Genetics; Gene","score_opus":0.0651366807759755,"score_gpt":0.4067274613496865,"score_spread":0.341590780573711,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086851723","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17469768,0.003170017,0.82118016,0.00043543466,0.00015207284,0.00030103026,0.000007597351,0.0000033631097,0.000052640116],"genre_scores_gemma":[0.83757484,0.000110492045,0.16187659,0.00019874217,0.00013332564,0.000055335444,0.000031259067,0.00001428038,0.0000051468587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891365,0.00027765206,0.00029025218,0.0003011025,0.000035145313,0.00018223157],"domain_scores_gemma":[0.99960816,0.00007604492,0.00006114929,0.00018586198,0.0000327028,0.000036069632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000670548,0.00012269987,0.00025289538,0.000042726482,0.00002621748,0.000012378117,0.00014544089,0.0001445787,0.0000011484692],"category_scores_gemma":[0.0003302508,0.00010453872,0.000053493994,0.000104779625,0.00006224279,0.0000020970126,0.00009647837,0.000097210126,1.4482178e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057567453,0.000012285673,0.0011999045,0.000050839466,0.000016403064,0.0000013157818,0.000113458525,0.0041796276,0.9931743,0.00039961582,0.000042096195,0.00075255387],"study_design_scores_gemma":[0.00043300973,0.00012351591,0.00019045062,0.000005738844,0.000009515618,0.000005114884,0.00009607363,0.06577112,0.92524403,0.00008237384,0.007925493,0.00011353295],"about_ca_topic_score_codex":0.000045544894,"about_ca_topic_score_gemma":0.000023275334,"teacher_disagreement_score":0.66287714,"about_ca_system_score_codex":0.0000085278625,"about_ca_system_score_gemma":0.000011864609,"threshold_uncertainty_score":0.42629653},"labels":[],"label_agreement":null},{"id":"W3087608513","doi":"10.1101/2020.09.21.305904","title":"Independent recruitment of PRC1 and PRC2 by human XIST","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"XIST; Biology; X-inactivation; Genetics; Chromatin; PRC2; Heterochromatin; Euchromatin; Dosage compensation; X chromosome; Computational biology; Gene; EZH2","score_opus":0.01999046416442683,"score_gpt":0.2774833767229077,"score_spread":0.25749291255848084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087608513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98987055,0.0048085647,0.0037602296,0.00013067096,0.00030816597,0.00077982777,0.00026733673,0.0000586614,0.000015986805],"genre_scores_gemma":[0.997101,0.00073485915,0.0015794643,0.000082500694,0.0002530329,0.00014932954,0.0000035922376,0.00008704321,0.000009153994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824077,0.00004773043,0.00040201584,0.00079928344,0.00021903779,0.0002911879],"domain_scores_gemma":[0.9986921,0.0000066391567,0.00021634778,0.00072819804,0.00013662927,0.00022011984],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020307735,0.00038517866,0.00038413654,0.0000622804,0.0000595685,0.00005286933,0.000317346,0.0004294834,0.000009001904],"category_scores_gemma":[0.00005754054,0.00043607343,0.000103225415,0.00009048063,0.00008703632,0.0000029471619,0.0006607731,0.00032004924,0.0000030202102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017123222,0.00006121472,0.002258531,0.00031271097,0.00014843036,0.000005837895,0.0000069908488,0.000033445085,0.9961613,0.00009959963,0.0008919343,0.0000029044588],"study_design_scores_gemma":[0.00042460422,0.00016103205,0.015060982,0.000104627645,0.000057530742,2.0191976e-8,0.000002888827,0.00003905001,0.963351,0.0000014680811,0.02034744,0.00044932743],"about_ca_topic_score_codex":0.000023778124,"about_ca_topic_score_gemma":0.0000023520604,"teacher_disagreement_score":0.03281025,"about_ca_system_score_codex":0.000036895704,"about_ca_system_score_gemma":0.00013127417,"threshold_uncertainty_score":0.9998091},"labels":[],"label_agreement":null},{"id":"W3088092039","doi":"10.1038/s41580-020-00288-9","title":"Applications of CRISPR–Cas in agriculture and plant biotechnology","year":2020,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":835,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Genome editing; Biotechnology; Computational biology; Biology; Gene; Computer science; Genetics","score_opus":0.0070462557609037,"score_gpt":0.32945378265994796,"score_spread":0.3224075268990443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088092039","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000055954483,0.9893827,0.008483029,0.00005160053,0.0000853182,0.0014784245,0.00014045862,0.000013511661,0.00035934872],"genre_scores_gemma":[0.0002358215,0.9964582,0.0016456612,0.00010814941,0.000110617046,0.00030423966,0.0010691887,0.000043239015,0.000024935875],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978549,0.00021014748,0.00075944595,0.00081166497,0.00005990608,0.00030396075],"domain_scores_gemma":[0.99891704,0.000025394027,0.00036353973,0.00056845765,0.000032416687,0.00009315421],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00019123599,0.0005147418,0.0017564835,0.00018475257,0.000021312875,0.0000065513846,0.00045092675,0.0025259375,0.0000047993944],"category_scores_gemma":[0.00010094413,0.00038799093,0.00040400706,0.00046294692,0.00010809039,0.0000011603333,0.00028789626,0.00097334397,0.000009788302],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000039929223,0.000040055995,0.0000047620333,0.009234491,0.00007434702,0.000015270329,0.0000073344368,0.0000011160319,0.034483235,0.00044440123,0.00048277475,0.95520824],"study_design_scores_gemma":[0.00013774092,0.00012185537,6.066694e-7,0.0007610326,0.00021486012,0.00006199673,0.0000040814025,0.0000010619245,0.015644968,0.000022008775,0.98267597,0.00035384065],"about_ca_topic_score_codex":0.000004666236,"about_ca_topic_score_gemma":0.000012989193,"teacher_disagreement_score":0.9821932,"about_ca_system_score_codex":0.000019687015,"about_ca_system_score_gemma":0.00008200845,"threshold_uncertainty_score":0.9998572},"labels":[],"label_agreement":null},{"id":"W3088289817","doi":"10.1038/s41598-020-72869-9","title":"PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eshelman Institute for Innovation, University of North Carolina at Chapel Hill; National Institute of Diabetes and Digestive and Kidney Diseases; Gillings School of Public Health; Genentech; National Institutes of Health; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Novartis Pharma; Canada Foundation for Innovation; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; North Carolina Biotechnology Center; National Cancer Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Innovative Medicines Initiative; Wellcome; GlaxoSmithKline; Pfizer","keywords":"Kinome; Kinase; Druggability; Drug discovery; Phosphorylation; Computational biology; Biology; Chemistry; Bioinformatics; Cell biology; Biochemistry; Gene","score_opus":0.008402648304327857,"score_gpt":0.2557390239622124,"score_spread":0.24733637565788452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088289817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883173,0.00049157516,0.0097169,0.00023981874,0.0006414684,0.0002790795,0.000010222228,0.00001886721,0.00028476331],"genre_scores_gemma":[0.9975296,0.00000557575,0.0018607007,0.00012002391,0.00022084403,0.000028169077,0.00008020541,0.000015721678,0.00013910719],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988087,0.000008349226,0.00022738276,0.0005990419,0.00012972539,0.00022683288],"domain_scores_gemma":[0.9994199,0.0000145891245,0.00009010994,0.00023760746,0.00008243211,0.00015532479],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001926212,0.00012048068,0.00012069785,0.00002244683,0.00010793411,0.000081411985,0.000060936494,0.00007972837,0.000008394686],"category_scores_gemma":[0.00030276473,0.000116803756,0.0000753004,0.00008829622,0.00008422531,0.0000053045815,0.00014447299,0.000059683352,9.624571e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031107516,0.000018995903,0.0002299066,0.00004906882,0.000011883679,0.000019601724,0.00045794362,0.00006546638,0.991459,0.000001286319,0.0061012716,0.0015544831],"study_design_scores_gemma":[0.00017103482,0.000096379066,0.000048012622,0.000010196592,0.00001829302,0.000021604761,0.00031677439,0.00041556347,0.9891548,0.00018015732,0.009416327,0.00015081873],"about_ca_topic_score_codex":0.0000043296195,"about_ca_topic_score_gemma":0.0000048743295,"teacher_disagreement_score":0.009212347,"about_ca_system_score_codex":0.0000075684284,"about_ca_system_score_gemma":0.00004492767,"threshold_uncertainty_score":0.4763119},"labels":[],"label_agreement":null},{"id":"W3088421407","doi":"10.1111/jeb.13693","title":"Resistance to natural and synthetic gene drive systems","year":2020,"lang":"en","type":"review","venue":"Journal of Evolutionary Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Engineering and Physical Sciences Research Council; European Society for Evolutionary Biology; Sight Research UK; Natural Environment Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; UK Research and Innovation; National Institutes of Health; National Science Foundation","keywords":"Biology; Resistance (ecology); Natural (archaeology); Gene; Genetics; Evolutionary biology; Natural selection; Synthetic biology; Computational biology; Ecology; Paleontology; Selection (genetic algorithm); Artificial intelligence; Computer science","score_opus":0.01029531013341294,"score_gpt":0.32715047139071063,"score_spread":0.3168551612572977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088421407","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011392948,0.9960194,0.0025326596,0.00009600375,0.0009233872,0.00019271081,0.00007164229,0.0000037606915,0.00004646404],"genre_scores_gemma":[0.0031176491,0.99365085,0.0017873202,0.000035554043,0.0010821577,0.000010122542,0.000058201098,0.000025951296,0.00023221009],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987742,0.00012830012,0.0005494957,0.00027636343,0.00007869868,0.00019296324],"domain_scores_gemma":[0.9992076,0.00004346681,0.00029968328,0.00017607759,0.00012015603,0.00015298346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013186186,0.00024207642,0.0008109528,0.000117514566,0.000040100167,0.000010629243,0.00024352795,0.00027186298,0.000002766118],"category_scores_gemma":[0.00017519423,0.00019039442,0.00023919482,0.000105823616,0.000059475464,0.000002022628,0.0001325614,0.00025323752,0.000006120394],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007369032,0.00023166738,0.00017832631,0.020576827,0.005195139,0.0006274957,0.00019653699,0.00067974784,0.06521128,0.0022946098,0.11615493,0.78791654],"study_design_scores_gemma":[0.00010296262,0.00027085203,0.000020266214,0.0009473619,0.00016546955,0.0011875436,0.000009238249,0.000007908264,0.000061227816,0.000014107117,0.99701685,0.00019620289],"about_ca_topic_score_codex":8.9675996e-7,"about_ca_topic_score_gemma":0.0000012202959,"teacher_disagreement_score":0.88086194,"about_ca_system_score_codex":0.00004554771,"about_ca_system_score_gemma":0.00018791127,"threshold_uncertainty_score":0.7764059},"labels":[],"label_agreement":null},{"id":"W3088639284","doi":"10.1038/s42003-020-01253-0","title":"Highly efficient gene transfer in the mouse gut microbiota is enabled by the Incl2 conjugative plasmid TP114","year":2020,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Compute Canada","keywords":"Plasmid; Horizontal gene transfer; Biology; Microbiome; Genetics; Bacteria; Gene; Pilus; Bacterial conjugation; Gene transfer; Microbiology; Bacterial genetics; Genome; Escherichia coli","score_opus":0.01699296501792371,"score_gpt":0.3042261348769247,"score_spread":0.287233169859001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088639284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95415777,0.0076126233,0.008214025,0.028312568,0.000045661414,0.00050789246,0.00026414412,0.000018635052,0.00086668803],"genre_scores_gemma":[0.99333507,0.0010441417,0.00037555475,0.004610495,0.000036663623,0.000073794814,0.00045211328,0.000012910358,0.000059266727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990829,0.0002490926,0.00021486459,0.0002212882,0.00003707616,0.00019477423],"domain_scores_gemma":[0.998782,0.000088659515,0.000026762158,0.0010238119,0.000042122745,0.00003669226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001861262,0.00013303515,0.00012372089,0.000019825942,0.0001601081,0.00001614187,0.0012232085,0.00012834065,0.000015016506],"category_scores_gemma":[0.00005152574,0.00008792514,0.000062707695,0.00015986954,0.0002701974,0.00000112126,0.00027955096,0.00021306713,0.000016877704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019026369,0.00005550409,0.00014949717,0.0000037248465,0.000033258744,1.4599317e-7,0.0016607727,0.000209497,0.99175626,0.00032433614,0.005549757,0.00023819436],"study_design_scores_gemma":[0.00066619366,0.00017108303,0.00035306453,0.0000034843888,0.000022080345,0.000008686232,0.0007303292,0.0016753256,0.6693237,0.000022786786,0.32682928,0.0001939963],"about_ca_topic_score_codex":0.000036868336,"about_ca_topic_score_gemma":0.000049840863,"teacher_disagreement_score":0.32243258,"about_ca_system_score_codex":0.000009900571,"about_ca_system_score_gemma":0.00003219882,"threshold_uncertainty_score":0.35854828},"labels":[],"label_agreement":null},{"id":"W3088656535","doi":"10.1016/j.coisb.2020.09.003","title":"Budding yeast as a factory to engineer partial and complete microbial genomes","year":2020,"lang":"en","type":"review","venue":"Current Opinion in Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Agence Nationale de la Recherche; International Development Research Centre","keywords":"Genome; Biology; Yeast; Synthetic biology; Bacterial genome size; Computational biology; Saccharomyces cerevisiae; Budding yeast; Genome engineering; Genetics; Genome editing; Gene","score_opus":0.06877207657369261,"score_gpt":0.4077412738239887,"score_spread":0.3389691972502961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088656535","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014579864,0.989015,0.0032043096,0.000012044786,0.006565752,0.0007173285,0.00030262984,0.000017883978,0.000019295594],"genre_scores_gemma":[0.0027052972,0.9940188,0.000051419804,0.0000074010327,0.002208818,0.00016185053,0.0007820851,0.00004637214,0.000017978078],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99828845,0.00014361166,0.0005424505,0.0006327173,0.00005426486,0.0003385211],"domain_scores_gemma":[0.9994282,0.00001878434,0.00011406797,0.00024700162,0.000025309895,0.00016661538],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012910378,0.00038776454,0.000932974,0.00015349861,0.000029512854,0.00002885201,0.0002240254,0.0003417295,0.000006155752],"category_scores_gemma":[0.00005121781,0.0003572673,0.00015614215,0.00012535471,0.00003957987,0.0000014955134,0.0002519873,0.00023183972,0.000047424375],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029251203,0.000050629704,0.00014231433,0.023111442,0.00026146122,0.0000031287627,0.00024210615,0.00013720509,0.0070256023,0.0003293067,0.0027432581,0.9659243],"study_design_scores_gemma":[0.00017602717,0.00012488545,0.000011141819,0.0021330672,0.000026033595,0.000059406124,0.000017381282,0.000025809552,0.00001875868,6.8864654e-7,0.9970394,0.00036740061],"about_ca_topic_score_codex":0.000016763259,"about_ca_topic_score_gemma":0.0000012922694,"teacher_disagreement_score":0.99429613,"about_ca_system_score_codex":0.000036689224,"about_ca_system_score_gemma":0.00010216678,"threshold_uncertainty_score":0.99988794},"labels":[],"label_agreement":null},{"id":"W3089106696","doi":"10.1371/journal.pone.0238950","title":"Peel-1 negative selection promotes screening-free CRISPR-Cas9 genome editing in Caenorhabditis elegans","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cas9; Genome; Biology; Caenorhabditis elegans; CRISPR; Genome editing; Genetics; Computational biology; Negative selection; Phenotype; Genome engineering; Gene","score_opus":0.022973806950290807,"score_gpt":0.24842927065699794,"score_spread":0.22545546370670713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089106696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979372,0.0004368904,0.01793095,0.0012605645,0.00003219338,0.00031987444,0.00004411197,0.000050813036,0.000552603],"genre_scores_gemma":[0.9877467,0.00005896496,0.010673343,0.00023075753,0.0010140787,0.000037082464,0.00007629185,0.000037111917,0.00012565978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989467,0.00003186093,0.00020314351,0.00035758739,0.00017202515,0.00028864655],"domain_scores_gemma":[0.99956936,0.000013575639,0.000050414495,0.00017364134,0.00008245372,0.0001105321],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008266662,0.00015906377,0.00018044465,0.00004465188,0.00005773617,0.000027002166,0.00018055856,0.000111481655,0.00004194794],"category_scores_gemma":[0.00044064596,0.00018498476,0.000047507685,0.00019569906,0.00002665094,0.0000065920917,0.000117678894,0.00018512699,0.0000091827715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003065502,0.00012766558,0.0043977597,0.000082591665,0.000097225515,0.000006548872,0.0003815014,0.0005097649,0.9937877,0.0000067279743,0.00024951182,0.00032233613],"study_design_scores_gemma":[0.0006413668,0.00043758177,0.0072483546,0.000051704865,0.000042824147,0.0000048578195,0.00017314222,0.0033726862,0.9872041,0.000028740382,0.00054634426,0.00024833583],"about_ca_topic_score_codex":0.00005939818,"about_ca_topic_score_gemma":0.00016431829,"teacher_disagreement_score":0.00837471,"about_ca_system_score_codex":0.000015770052,"about_ca_system_score_gemma":0.00002767411,"threshold_uncertainty_score":0.75434595},"labels":[],"label_agreement":null},{"id":"W3089192623","doi":"10.1101/2020.09.25.314047","title":"A versatile toolkit for CRISPR-Cas13-based RNA manipulation in <i>Drosophila</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Institute of Genetics; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"CRISPR; Biology; Computational biology; microRNA; RNA; Endonuclease; Gene; Genetics","score_opus":0.01680025751364592,"score_gpt":0.26045246507074393,"score_spread":0.24365220755709802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089192623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8993757,0.0015773323,0.09498696,0.00068223564,0.0011530985,0.0016071497,0.00043648368,0.00015887606,0.000022200245],"genre_scores_gemma":[0.99013245,0.0000836678,0.008173532,0.00036084192,0.0007308167,0.00036713516,0.000009434373,0.00013858105,0.0000035615026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785846,0.000046706416,0.00046397702,0.0009759311,0.00020181414,0.00045312438],"domain_scores_gemma":[0.998605,0.00002567574,0.00018042701,0.00082051865,0.00018507002,0.00018327826],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025895244,0.00046602738,0.0004034015,0.0001366679,0.00006462735,0.00008589721,0.0003926756,0.00055981637,0.000009987739],"category_scores_gemma":[0.00022790158,0.0005776755,0.00021141028,0.00020761916,0.000040634804,0.00000648858,0.00025437216,0.00034279894,0.000011101608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010420437,0.00006116257,0.0016860918,0.00042830306,0.000056943434,0.000011654423,0.000004835879,0.007701579,0.9891563,0.00007667839,0.00070893695,0.0000033308181],"study_design_scores_gemma":[0.0012502364,0.00014875934,0.026126236,0.00015974192,0.00007567727,1.0296715e-8,0.0000020980233,0.009101024,0.9498337,0.000005289969,0.012518266,0.0007789473],"about_ca_topic_score_codex":0.00002362585,"about_ca_topic_score_gemma":0.0000067965425,"teacher_disagreement_score":0.09075677,"about_ca_system_score_codex":0.00009466322,"about_ca_system_score_gemma":0.0003383748,"threshold_uncertainty_score":0.99966747},"labels":[],"label_agreement":null},{"id":"W3089891152","doi":"10.1016/j.nmd.2020.09.014","title":"LATE BREAKING NEWS E-POSTER PRESENTATION","year":2020,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Exon; Genome editing; Biology; Duchenne muscular dystrophy; Plasmid; Gene; Exon skipping; Dystrophin; Reverse transcriptase; Sanger sequencing; Genetics; Stop codon; Point mutation; Coding region; CRISPR; Molecular biology; Computational biology; Mutation; RNA; Alternative splicing","score_opus":0.008121914963258111,"score_gpt":0.2669067502553312,"score_spread":0.25878483529207313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089891152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96161246,0.000731304,0.032652963,0.0021396407,0.00018004577,0.0002359161,0.0000048800625,0.00004818289,0.0023945863],"genre_scores_gemma":[0.9977354,0.00025457994,0.00024038662,0.0014171592,0.00016310002,0.000010353213,0.00006480617,0.000032154545,0.00008208048],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999277,0.000030183955,0.00011733669,0.00029809226,0.000102425285,0.00017497536],"domain_scores_gemma":[0.9996782,0.0000041842186,0.000025450852,0.00018961594,0.00001516503,0.00008736741],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000026508686,0.000118332304,0.000077731806,0.000016902402,0.000038266306,0.000024499226,0.00012144505,0.000057717454,0.00002774694],"category_scores_gemma":[0.000050560193,0.00012493244,0.00009579622,0.000080236816,0.000019549298,0.0000036234367,0.00007152064,0.00006680409,0.000021246686],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054554566,0.000033075892,0.009774672,0.000063063,0.00006046083,0.0000054183843,0.00031886235,0.013517673,0.9424043,0.000016787477,0.0027523616,0.030998737],"study_design_scores_gemma":[0.0023935265,0.00073040964,0.041105106,0.000017459752,0.000096512165,0.0000124370035,0.00025517683,0.0059128725,0.25798276,0.00009867435,0.69046634,0.00092872046],"about_ca_topic_score_codex":0.000017388427,"about_ca_topic_score_gemma":0.000030458576,"teacher_disagreement_score":0.687714,"about_ca_system_score_codex":0.000001920436,"about_ca_system_score_gemma":0.000010715361,"threshold_uncertainty_score":0.50945973},"labels":[],"label_agreement":null},{"id":"W3089940525","doi":"10.1074/jbc.ra120.013772","title":"A saturating mutagenesis CRISPR-Cas9–mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Health and Medical Research Council; Department of Health and Aged Care, Australian Government; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Enhancer; Biology; Gene; Genetics; Promoter; Cas9; Regulatory sequence; Mutagenesis; Regulation of gene expression; Genome; Transcription factor; Computational biology; Gene expression; Mutation","score_opus":0.017224997807992835,"score_gpt":0.2605653673189294,"score_spread":0.24334036951093654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089940525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946082,0.0032083169,0.0019004968,0.00011579828,0.000038822247,0.00005111202,0.000023734498,0.00000391418,0.000049588736],"genre_scores_gemma":[0.9984812,0.0004739388,0.00063331565,0.000086165426,0.0002590757,0.0000016231747,0.000038465212,0.000009061064,0.000017142784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989711,0.000024790828,0.00053134916,0.0001919947,0.00012600291,0.00015474536],"domain_scores_gemma":[0.99950516,0.000026887386,0.00019368519,0.00008408767,0.00007180546,0.00011835005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020240257,0.00013992183,0.0002542257,0.000022484317,0.000022346285,0.000010297613,0.0001297691,0.00016936228,0.000065653265],"category_scores_gemma":[0.00017343798,0.00011583219,0.000109833294,0.00007717061,0.00007474494,0.000004594765,0.00006897863,0.00016018447,3.680293e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021921037,0.00003327756,0.014009032,0.000073555195,0.00006119945,0.000012833407,0.00003647199,0.00028615494,0.9844513,4.2138925e-7,0.00010412148,0.0007124047],"study_design_scores_gemma":[0.00089764217,0.00020904173,0.08888258,0.000029447263,0.000021259391,0.000052630643,0.0001573391,0.00015789377,0.9089441,0.0000106924035,0.00050082424,0.00013657167],"about_ca_topic_score_codex":0.0000022944666,"about_ca_topic_score_gemma":0.0000013696235,"teacher_disagreement_score":0.07550724,"about_ca_system_score_codex":0.000011179507,"about_ca_system_score_gemma":0.000037173468,"threshold_uncertainty_score":0.47234997},"labels":[],"label_agreement":null},{"id":"W3090467525","doi":"10.1016/j.gfs.2020.100440","title":"Regulatory barriers to improving global food security","year":2020,"lang":"en","type":"article","venue":"Global Food Security","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canada First Research Excellence Fund","keywords":"Food security; Business; Agriculture; Emerging technologies; Crop; Biotechnology; Food processing; Abiotic component; Natural resource economics; Marketing; Risk analysis (engineering); Computer science; Economics; Biology; Agronomy; Ecology","score_opus":0.005911610598903976,"score_gpt":0.2568364683481112,"score_spread":0.2509248577492072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3090467525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902884,0.0018302682,0.0038003498,0.0004525434,0.00040373302,0.00033697247,0.0007772185,0.00009877248,0.002011737],"genre_scores_gemma":[0.9970623,0.000015731051,0.00041401194,0.001870056,0.0005358748,0.000016359625,0.00006205768,0.000019877565,0.0000037272348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981199,0.000049157137,0.00028293458,0.00071728823,0.000274483,0.00055623474],"domain_scores_gemma":[0.99835604,0.0000035720086,0.0000548599,0.00046780382,0.00008864018,0.0010290665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012852333,0.00031862524,0.00025268726,0.0000121467465,0.00012147746,0.000053935084,0.00041059408,0.00025462414,0.000033324977],"category_scores_gemma":[0.00027654206,0.0003630089,0.00019265812,0.00030001992,0.000053381693,0.000007231049,0.0004375348,0.00014214555,0.0000238897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0081401635,0.0013337247,0.1491352,0.003856109,0.0052864277,0.00026569807,0.013288259,0.01911575,0.4142375,0.10459327,0.22456302,0.056184884],"study_design_scores_gemma":[0.00799582,0.025425946,0.02213602,0.00013359032,0.0004676707,0.00027685388,0.0038932273,0.004971184,0.5365212,0.025090106,0.36684296,0.0062454175],"about_ca_topic_score_codex":0.000044592933,"about_ca_topic_score_gemma":0.00028677695,"teacher_disagreement_score":0.14227995,"about_ca_system_score_codex":0.00008455258,"about_ca_system_score_gemma":0.00018009434,"threshold_uncertainty_score":0.99988216},"labels":[],"label_agreement":null},{"id":"W3090576692","doi":"10.1002/ctm2.194","title":"Improving transgene expression and CRISPR‐Cas9 efficiency with molecular engineering‐based molecules","year":2020,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"National Key Research and Development Program of China; Natural Science Foundation of Guangdong Province; Government of Jiangxi Province; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Transgene; Genome editing; Biology; Gene; Computational biology; Genetic enhancement; Plasmid; Cell biology; Genetics","score_opus":0.015744418578165838,"score_gpt":0.3119143305036433,"score_spread":0.2961699119254775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3090576692","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4186034,0.002928104,0.5761815,0.0020809676,0.00003368867,0.00010921729,0.000006418336,0.000015073695,0.00004164783],"genre_scores_gemma":[0.9910181,0.00010390656,0.007918269,0.00067295984,0.00021147513,0.000006785201,0.00004727108,0.000017332828,0.0000038797916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913,0.00001957366,0.000249825,0.00033519792,0.00013547525,0.00012990607],"domain_scores_gemma":[0.9995906,0.0000489893,0.000027426231,0.00008894555,0.00003476671,0.00020931738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119608,0.00014282452,0.00017757538,0.000021450855,0.000034939316,0.0000065853937,0.000056275985,0.00009106796,0.000009769074],"category_scores_gemma":[0.00007400888,0.000106958374,0.000037644517,0.00006338448,0.00014235573,0.000002898466,0.0000117223535,0.00011316577,3.533291e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002424383,0.000038373775,0.0041195876,0.00016891722,0.00003403339,0.000015782169,0.00008724323,0.005850131,0.98168755,0.00012841648,0.000028181923,0.0075993664],"study_design_scores_gemma":[0.017716862,0.006537686,0.06141991,0.00052189577,0.00039427285,0.00007302916,0.00012752655,0.23959926,0.6600791,0.00012240982,0.01210767,0.001300377],"about_ca_topic_score_codex":0.0000023226412,"about_ca_topic_score_gemma":9.4205893e-7,"teacher_disagreement_score":0.57241476,"about_ca_system_score_codex":5.0046236e-7,"about_ca_system_score_gemma":0.00002468606,"threshold_uncertainty_score":0.4361636},"labels":[],"label_agreement":null},{"id":"W3091008282","doi":"10.1038/s41592-020-0966-x","title":"An efficient KRAB domain for CRISPRi applications in human cells","year":2020,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":280,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada First Research Excellence Fund; University of Toronto; Government of Canada; Canadian Institute for Advanced Research","keywords":"Gene silencing; Repressor; Biology; Krüppel; Genetics; Gene; RNA interference; GATAD2B; Computational biology; Gene expression; Cell biology; RNA","score_opus":0.010969541057592005,"score_gpt":0.4242262242411435,"score_spread":0.41325668318355147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091008282","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11536957,0.0011472635,0.8826035,0.00015392237,0.00007776336,0.00036703798,0.000017140423,0.000016242731,0.00024755715],"genre_scores_gemma":[0.62379307,0.0000070933575,0.37545687,0.00032258613,0.00023782821,0.00007399737,0.00007038044,0.000017906928,0.000020262845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992826,0.00006584747,0.00013111068,0.00030796634,0.000052393745,0.00016007945],"domain_scores_gemma":[0.99958956,0.000023618772,0.00002419564,0.00024163966,0.000032790977,0.00008819527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003018354,0.00010587609,0.0001130062,0.000028201695,0.000049584152,0.00001213351,0.00017756406,0.00024370188,0.0000049692135],"category_scores_gemma":[0.000040378734,0.00010290759,0.000063156614,0.00011477236,0.000017527527,7.845993e-7,0.000033782686,0.000179877,5.919071e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011523151,0.000033241446,0.000052491654,0.000025512283,0.0000068333798,2.3992666e-7,0.000112226204,0.004810524,0.99186784,0.0005188934,0.00026275043,0.0022979337],"study_design_scores_gemma":[0.00030149316,0.00011452596,0.00037139127,0.0000021517685,0.0000081819035,5.0095025e-7,0.00009293502,0.0016235245,0.8884635,0.0001662686,0.10872481,0.00013071156],"about_ca_topic_score_codex":0.000001552154,"about_ca_topic_score_gemma":0.0000036337572,"teacher_disagreement_score":0.5084235,"about_ca_system_score_codex":0.000007158151,"about_ca_system_score_gemma":0.000014303429,"threshold_uncertainty_score":0.41964495},"labels":[],"label_agreement":null},{"id":"W3092006260","doi":"10.1186/s13059-020-02170-5","title":"Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize","year":2020,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":274,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Transgenic Science and Technology Program; China Agricultural University; National Natural Science Foundation of China","keywords":"Biology; Genetics; Gene; Human genetics; Computational biology","score_opus":0.013429856301341189,"score_gpt":0.3263747743703121,"score_spread":0.3129449180689709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092006260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909408,0.0059054545,0.002259179,0.00037097477,0.00012689726,0.00017549335,0.000019496832,0.000011851038,0.00018983471],"genre_scores_gemma":[0.99739665,0.00024042526,0.0014972166,0.00022520505,0.00038520125,0.000028220018,0.00017228765,0.00001532031,0.000039465864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906737,0.000036484165,0.00022492025,0.00036033607,0.000030644424,0.00028022312],"domain_scores_gemma":[0.9997405,0.000011598242,0.000035813508,0.00011637844,0.000021773134,0.00007392608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012091714,0.00013125384,0.00016448203,0.000065110224,0.000031719817,0.000013363062,0.000105787214,0.00009216287,0.000015742455],"category_scores_gemma":[0.00003296172,0.00013464654,0.000028017532,0.00013511903,0.000055546636,0.0000021388523,0.00011425173,0.0000787906,0.000007733497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030395877,0.000015155408,0.017025389,0.000012115999,0.000011202224,0.0000045435377,0.00020733218,0.0032908253,0.978134,0.00006367957,0.0000143989655,0.0011909567],"study_design_scores_gemma":[0.0045838915,0.0005822496,0.041608527,0.000016675116,0.000022081254,0.000037290494,0.00055565924,0.0036319,0.9142876,0.00012780975,0.03385591,0.00069039845],"about_ca_topic_score_codex":0.00005755308,"about_ca_topic_score_gemma":0.00017182493,"teacher_disagreement_score":0.0638464,"about_ca_system_score_codex":0.000010892782,"about_ca_system_score_gemma":0.0000307904,"threshold_uncertainty_score":0.5490727},"labels":[],"label_agreement":null},{"id":"W3092383842","doi":"10.1038/s41580-020-00312-y","title":"Author Correction: Applications of CRISPR–Cas in agriculture and plant biotechnology","year":2020,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Biotechnology; Agriculture; Agricultural biotechnology; Biology; Computational biology; Genetics; Gene; Ecology","score_opus":0.009162315418170974,"score_gpt":0.3404267912492407,"score_spread":0.3312644758310697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092383842","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000042055135,0.98587865,0.011789777,0.00008575609,0.00031537126,0.0014719315,0.00009792364,0.000017906854,0.0003384556],"genre_scores_gemma":[0.00021906522,0.9967933,0.0012472161,0.000091118454,0.00015782393,0.00034506936,0.0009890206,0.000042767606,0.000114591654],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99779457,0.00023772236,0.0007762813,0.000832949,0.000064439606,0.00029406816],"domain_scores_gemma":[0.9988882,0.000030641942,0.00039256635,0.0005487304,0.00004086629,0.000098993456],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002148578,0.000513829,0.0016723742,0.00019484415,0.000029204273,0.000007866763,0.00039252438,0.0026327183,0.000006483355],"category_scores_gemma":[0.00013650398,0.00039517414,0.0004055693,0.0005431301,0.00010605695,0.0000013947708,0.000245306,0.0010924103,0.00001037372],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005505507,0.00004427272,0.0000052663167,0.006387348,0.00007771881,0.000014190503,0.000009863133,0.0000026634755,0.021930452,0.00022338395,0.0023166498,0.9689827],"study_design_scores_gemma":[0.00012095973,0.00014745041,9.560936e-7,0.00080217596,0.00023417667,0.000108118766,0.0000066498774,0.0000034291165,0.014862789,0.000012786592,0.9833409,0.00035961176],"about_ca_topic_score_codex":0.000005721288,"about_ca_topic_score_gemma":0.000017542527,"teacher_disagreement_score":0.98102427,"about_ca_system_score_codex":0.000025754407,"about_ca_system_score_gemma":0.00009254732,"threshold_uncertainty_score":0.99985003},"labels":[],"label_agreement":null},{"id":"W3092410196","doi":"10.1088/2516-1091/abbf5e","title":"Critical review on where CRISPR meets molecular diagnostics","year":2020,"lang":"en","type":"article","venue":"Progress in Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Air Force Office of Scientific Research; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Nucleic acid detection; Molecular diagnostics; Computational biology; Computer science; Trans-activating crRNA; Nanotechnology; Genome editing; Nucleic acid; Biology; Bioinformatics; Genetics; Gene; Materials science","score_opus":0.009715140046815061,"score_gpt":0.31865405437331495,"score_spread":0.3089389143264999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092410196","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.031204404,0.71106076,0.21891783,0.036012366,0.0010832973,0.0010372322,0.00005361711,0.00028573978,0.0003447391],"genre_scores_gemma":[0.9740431,0.014472909,0.008955442,0.0019677107,0.00033006308,0.00010983061,0.000054232973,0.00006322225,0.0000035352741],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986357,0.000021294303,0.0002962948,0.00039226015,0.00027415113,0.00038028028],"domain_scores_gemma":[0.9993435,0.000046280424,0.00001975342,0.0002292366,0.00003648748,0.00032475652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013654644,0.00022038927,0.00024073468,0.00004849249,0.000016871445,0.000018322004,0.00024286965,0.00015915655,0.00003221196],"category_scores_gemma":[0.0012024319,0.00021616154,0.00008308982,0.0002384523,0.000078866535,0.0000032052455,0.00012792747,0.00024458952,0.000016176773],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040843835,0.0023383573,0.010353141,0.04759808,0.000711709,0.004457757,0.00061736745,0.02108474,0.4794589,0.012966192,0.096312046,0.32369328],"study_design_scores_gemma":[0.0019167428,0.0018613697,0.001884945,0.0068354644,0.00012098027,0.00007940387,0.00002973986,0.042707894,0.13581908,0.00003868602,0.8069226,0.0017830835],"about_ca_topic_score_codex":6.612116e-7,"about_ca_topic_score_gemma":2.9028138e-7,"teacher_disagreement_score":0.94283867,"about_ca_system_score_codex":0.000013180632,"about_ca_system_score_gemma":0.000024073963,"threshold_uncertainty_score":0.8814812},"labels":[],"label_agreement":null},{"id":"W3092450568","doi":"10.1007/s00294-020-01114-7","title":"Gene repression in S. cerevisiae—looking beyond Sir-dependent gene silencing","year":2020,"lang":"en","type":"review","venue":"Current Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Psychological repression; Chromatin; Genetics; Histone; Epigenetics; Gene silencing; Regulation of gene expression; Gene; Cell biology; Computational biology; Gene expression","score_opus":0.029921062077748837,"score_gpt":0.3690932622827243,"score_spread":0.33917220020497546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092450568","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008683688,0.99308705,0.0036291978,0.000010010377,0.0013987516,0.000732465,0.00010187432,0.00003418854,0.00013808456],"genre_scores_gemma":[0.001519775,0.99474114,0.0011097024,0.000022565608,0.0015109626,0.00009507718,0.0007714096,0.00016543274,0.00006392702],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964909,0.00015356728,0.0010960154,0.001266773,0.00036607674,0.00062667823],"domain_scores_gemma":[0.99831754,0.00003001108,0.00033859597,0.0009923558,0.00005316824,0.0002683531],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002572342,0.00077945483,0.0012617111,0.00018945495,0.00007519865,0.00006980513,0.00067937776,0.00053442677,0.000024275052],"category_scores_gemma":[0.000090901594,0.00077105215,0.0005018739,0.00030217564,0.000044782355,0.0000032164455,0.00074267236,0.0006325059,0.000041320192],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005560292,0.00005546009,0.00003384936,0.0040135197,0.00007943382,0.000028627173,0.000060179467,0.00073864614,0.006227214,0.0000028561083,0.00035807828,0.9883966],"study_design_scores_gemma":[0.00034793737,0.00010199592,0.000015315441,0.0030402448,0.00034115257,0.0000734697,0.000011677183,0.00018057413,0.020954546,0.000012736002,0.9740277,0.00089264906],"about_ca_topic_score_codex":0.0000027978965,"about_ca_topic_score_gemma":0.0000057345737,"teacher_disagreement_score":0.98750395,"about_ca_system_score_codex":0.000101382946,"about_ca_system_score_gemma":0.00031671382,"threshold_uncertainty_score":0.99947405},"labels":[],"label_agreement":null},{"id":"W3092525888","doi":"10.1016/j.pbiomolbio.2020.09.010","title":"Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease","year":2020,"lang":"en","type":"review","venue":"Progress in Biophysics and Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; National Institute on Aging; Cancer Prevention and Research Institute of Texas","keywords":"Biology; DNA; Genetics; Sequence motif; Conserved sequence; Human genome; Genome; Computational biology; Cell biology; Gene; Peptide sequence","score_opus":0.02038348301095347,"score_gpt":0.3790969081994399,"score_spread":0.3587134251884864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092525888","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.021855377,0.97307247,0.0038241444,0.000022638062,0.00011288086,0.00093105715,0.00015486658,0.000015613712,0.000010970326],"genre_scores_gemma":[0.08299878,0.9143838,0.0010837188,0.000095083036,0.0001526924,0.00042142736,0.00078543654,0.000073235344,0.000005776189],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982541,0.000079484984,0.00035863766,0.0008766952,0.00006158449,0.00036948506],"domain_scores_gemma":[0.99925894,0.000016212001,0.00014008446,0.00033604598,0.000044769855,0.00020396871],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000084481915,0.00046905476,0.00074345997,0.00008760057,0.000075516145,0.00003990087,0.00022629765,0.00033375423,3.6268105e-7],"category_scores_gemma":[0.00002911524,0.00042728355,0.0001923253,0.00014395209,0.0002469071,0.0000029184225,0.00036385382,0.0001679075,4.4138616e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045734723,0.00013094148,0.00021593254,0.010818439,0.00033293612,0.000104721286,0.00009220383,0.000024423725,0.13992563,0.0060649887,0.000017791217,0.84222627],"study_design_scores_gemma":[0.00063228497,0.00062632025,0.000052396255,0.0013251955,0.00032556453,0.000024824578,0.000012240528,0.00009316412,0.011577647,0.0038376877,0.9803891,0.0011035344],"about_ca_topic_score_codex":0.0000033363538,"about_ca_topic_score_gemma":0.0000044092285,"teacher_disagreement_score":0.98037136,"about_ca_system_score_codex":0.000022421043,"about_ca_system_score_gemma":0.00011416167,"threshold_uncertainty_score":0.9998179},"labels":[],"label_agreement":null},{"id":"W3092862293","doi":"10.1021/acsomega.0c03508","title":"Phage-Assisted Continuous Evolution (PACE): A Guide Focused on Evolving Protein–DNA Interactions","year":2020,"lang":"en","type":"review","venue":"ACS Omega","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Pace; Selection (genetic algorithm); Directed Molecular Evolution; Directed evolution; Computer science; Computational biology; Biology; Genetics; Artificial intelligence; Gene","score_opus":0.01912615642350137,"score_gpt":0.33331595956479476,"score_spread":0.3141898031412934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092862293","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023600916,0.9901596,0.005280924,0.00007213846,0.00043389844,0.0010483034,0.00006877758,0.000079282494,0.0026210966],"genre_scores_gemma":[0.019521922,0.9702423,0.0016002001,0.000080946,0.0012078396,0.0005346742,0.0006528528,0.00019367384,0.0059655826],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99822634,0.00009637636,0.0005178029,0.0006388698,0.00017703659,0.0003435564],"domain_scores_gemma":[0.998913,0.00003264678,0.00022971744,0.0005941741,0.00009012145,0.00014035734],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001193194,0.00046692838,0.00078080123,0.00013103725,0.00011135482,0.000068664995,0.00033080622,0.00032514133,0.000012331032],"category_scores_gemma":[0.00035231854,0.000440325,0.00042654414,0.00025384393,0.000032018695,0.0000052395594,0.00016607612,0.00037220895,0.000099414225],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002348059,0.00010112324,0.0000020583043,0.002501416,0.00047270625,0.00003877647,0.000029204504,0.0000120278655,0.025638469,0.00006032944,0.016713474,0.9544069],"study_design_scores_gemma":[0.00028009492,0.00022963867,0.000008951302,0.002188999,0.00025495235,0.000056792724,0.000014699766,0.000018423836,0.0025173665,0.00000536174,0.9939869,0.00043780537],"about_ca_topic_score_codex":0.000019513238,"about_ca_topic_score_gemma":0.000025535446,"teacher_disagreement_score":0.97727346,"about_ca_system_score_codex":0.00013690471,"about_ca_system_score_gemma":0.00020273743,"threshold_uncertainty_score":0.99980485},"labels":[],"label_agreement":null},{"id":"W3093290150","doi":"10.1007/s12161-020-01889-y","title":"Effect of Amount of DNA on Digital PCR Assessment of Genetically Engineered Canola and Soybean Events","year":2020,"lang":"en","type":"article","venue":"Food Analytical Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Digital polymerase chain reaction; Canola; DNA; Polymerase chain reaction; Chromatography; Genetically modified organism; Real-time polymerase chain reaction; genomic DNA; Chemistry; Biology; Food science; Genetics; Gene","score_opus":0.014359766996376247,"score_gpt":0.37191563235825376,"score_spread":0.3575558653618775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093290150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8481596,0.00017897697,0.15097043,0.000047184523,0.000031500633,0.000120127326,0.00004470969,0.000004304695,0.0004431831],"genre_scores_gemma":[0.97975993,0.000015476897,0.02012295,0.000016285416,0.00004457236,0.0000033440076,0.000013798848,0.000015169549,0.000008460936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907655,0.00010142432,0.0003037642,0.00022668901,0.00015006762,0.00014150568],"domain_scores_gemma":[0.99943674,0.00013091203,0.000060774553,0.00019140747,0.00004823727,0.00013192327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002784956,0.00014246319,0.0003512385,0.000036159505,0.0000075896187,0.000003386816,0.00011393219,0.0000953337,0.0000068057752],"category_scores_gemma":[0.00043069982,0.0001207213,0.0001270786,0.000099811485,0.00006237272,0.0000016648469,0.000091609276,0.000075894066,1.5856368e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013743434,0.00006970424,0.0029902132,0.00034203051,0.000277217,7.6942507e-7,0.000024908635,0.0011705513,0.9773447,0.00036690506,0.000014531205,0.017261053],"study_design_scores_gemma":[0.00060370436,0.0065864,0.008282107,0.000030984047,0.00010105373,0.0000016666703,0.000010359234,0.014472467,0.96957654,0.000026644288,0.00018208938,0.00012597555],"about_ca_topic_score_codex":0.0000013922537,"about_ca_topic_score_gemma":3.0286324e-7,"teacher_disagreement_score":0.13160035,"about_ca_system_score_codex":0.0000050388185,"about_ca_system_score_gemma":0.000028094591,"threshold_uncertainty_score":0.49228716},"labels":[],"label_agreement":null},{"id":"W3093412637","doi":"10.1126/science.aaz0863","title":"The GATOR–Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids","year":2020,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Occupational Cancer Research Centre; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Genome Canada","keywords":"mTORC1; Lysosome; Cell biology; GTPase; Amino acid; Chemistry; Small GTPase; Biology; Signal transduction; Biochemistry; PI3K/AKT/mTOR pathway; Enzyme","score_opus":0.00747759065100929,"score_gpt":0.2579841935871065,"score_spread":0.2505066029360972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093412637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857265,0.00039943474,0.012421793,0.0007929443,0.00011789966,0.00009890175,0.0000063824764,0.000019156081,0.00041700187],"genre_scores_gemma":[0.9990593,0.00004767182,0.00014983017,0.000456461,0.00012779562,0.0000089228815,0.000009814845,0.0000080795,0.00013211097],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999171,0.000012663362,0.000101398844,0.00029230322,0.00019230043,0.00023029804],"domain_scores_gemma":[0.99956423,0.00000943422,0.0000320081,0.00020810649,0.000057251204,0.00012896878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015887555,0.00008952106,0.00005247812,0.0000126192745,0.00022575194,0.0000638682,0.00030011515,0.000041801173,0.0000050045496],"category_scores_gemma":[0.00022940226,0.00006901873,0.000028985598,0.00023045455,0.00019618825,0.000007818628,0.00012613012,0.000061853694,0.000011135374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000075770618,0.0000050882354,0.00022620094,0.0000032171313,0.0000023337834,2.5842166e-7,0.00009457979,0.000098899625,0.9958712,0.00002798051,0.00069516676,0.0029674964],"study_design_scores_gemma":[0.000120295,0.0000790665,0.0010355623,0.0000033260492,0.0000014881168,0.0000012100278,0.000093948285,0.0003641352,0.953568,0.000011384925,0.044625767,0.00009585851],"about_ca_topic_score_codex":0.0000022904287,"about_ca_topic_score_gemma":0.000001620404,"teacher_disagreement_score":0.043930598,"about_ca_system_score_codex":0.000011537403,"about_ca_system_score_gemma":0.00009173229,"threshold_uncertainty_score":0.2814502},"labels":[],"label_agreement":null},{"id":"W3093545770","doi":"10.1002/1873-3468.13962","title":"Structural plasticity of substrate selection by activation‐induced cytidine deaminase as a regulator of its genome‐wide mutagenic activity","year":2020,"lang":"en","type":"article","venue":"FEBS Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Memorial University of Newfoundland","funders":"Institute of Infection and Immunity; Natural Sciences and Engineering Research Council of Canada","keywords":"Cytidine deaminase; Regulator; Activation-induced (cytidine) deaminase; Cytidine; Substrate specificity; Substrate (aquarium); Chemistry; Genome; Selection (genetic algorithm); Biology; Biochemistry; Genetics; Enzyme; Cell biology; Computational biology; Biophysics; Gene; Somatic hypermutation; Computer science","score_opus":0.009621508241413182,"score_gpt":0.2480162277420667,"score_spread":0.2383947195006535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093545770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99180055,0.000040507843,0.007432273,0.000494724,0.000036832582,0.00014304566,0.000027690756,0.0000113260485,0.000013074152],"genre_scores_gemma":[0.9994221,0.000008310692,0.00014553878,0.00025005476,0.0000928629,0.0000050470358,0.00004427532,0.000016926351,0.000014939583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930334,0.000026573045,0.0001691196,0.00023074231,0.0001157096,0.00015452322],"domain_scores_gemma":[0.99965376,0.000015281415,0.00011143029,0.00009707062,0.00004826368,0.0000742132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000035954505,0.0001330108,0.0001544247,0.000026615045,0.00002973847,0.000006167864,0.00009753274,0.00007971133,0.000020074569],"category_scores_gemma":[0.00010123966,0.0001410801,0.00006977836,0.0001236024,0.000024474744,0.0000067524893,0.000035122746,0.00008314594,0.0000014226534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015615422,0.000011194384,0.00075030955,0.000065780114,0.000059261776,6.74141e-7,0.00006446827,0.0042130086,0.9943109,0.0000020179298,0.00020065958,0.00016555455],"study_design_scores_gemma":[0.00036590092,0.0002120754,0.031206457,0.0000067399124,0.000020346979,0.0000033017684,0.000014022215,0.001204908,0.9667023,9.816634e-7,0.00013556545,0.0001274403],"about_ca_topic_score_codex":0.00002298175,"about_ca_topic_score_gemma":0.0000049903574,"teacher_disagreement_score":0.030456148,"about_ca_system_score_codex":0.00001583932,"about_ca_system_score_gemma":0.00003226317,"threshold_uncertainty_score":0.57530797},"labels":[],"label_agreement":null},{"id":"W3094372258","doi":"10.3389/fgeed.2020.591592","title":"Regulatory Barriers to Innovative Plant Breeding in Canada","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Scrutiny; Novelty; Pace; Biotechnology; Plant breeding; Genome editing; Emerging technologies; Private sector; Business; Biology; Environmental resource management; Genome; Political science; Geography; Computer science; Economics; Gene; Genetics","score_opus":0.005278101311671412,"score_gpt":0.21259036600846068,"score_spread":0.20731226469678926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094372258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98290366,0.0005417204,0.014292319,0.00044675314,0.0011502694,0.0001606046,0.000044364722,0.000007651383,0.00045264722],"genre_scores_gemma":[0.99440885,0.00000987311,0.0037595977,0.0009491611,0.0007805053,0.000013312998,0.000044887238,0.00001974204,0.0000140742295],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990393,0.00001539543,0.00022896737,0.00029093647,0.000116778196,0.00030863038],"domain_scores_gemma":[0.99962795,0.000004827675,0.000034912242,0.000106128304,0.00002734947,0.00019885259],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012633187,0.00012175327,0.00015353304,0.000075171854,0.000029784806,0.000008950072,0.00015873773,0.000054446944,0.000008671401],"category_scores_gemma":[0.00026167478,0.00014766109,0.000016229395,0.00035433628,0.0000125534125,0.0000029830398,0.00009308506,0.00013835044,5.690002e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000098436285,0.000007070143,0.45090243,0.00008819805,0.00005880955,0.00013051332,0.0029918754,0.056009397,0.43261304,0.000019653335,0.053701345,0.0033792306],"study_design_scores_gemma":[0.0037836644,0.00067997706,0.2770924,0.00029054255,0.000022580452,0.00003336082,0.06394788,0.020320747,0.36952886,0.000052556832,0.2614855,0.002761977],"about_ca_topic_score_codex":0.014245924,"about_ca_topic_score_gemma":0.057175376,"teacher_disagreement_score":0.20778413,"about_ca_system_score_codex":0.0001682168,"about_ca_system_score_gemma":0.00042176413,"threshold_uncertainty_score":0.9923183},"labels":[],"label_agreement":null},{"id":"W3094576829","doi":"10.1089/crispr.2020.0082","title":"Human Germline and Heritable Genome Editing: The Global Policy Landscape","year":2020,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":145,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Dalhousie University","keywords":"Germline; Genome editing; Genome; Biology; Legislation; Human genome; Genetics; Human genetics; Political science; Evolutionary biology; Computational biology; Gene; Law","score_opus":0.010900311860745443,"score_gpt":0.3084203935389081,"score_spread":0.2975200816781627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094576829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94450206,0.009916513,0.00887616,0.033511735,0.00019696065,0.00013677555,0.000023204962,0.000018967308,0.0028176242],"genre_scores_gemma":[0.99355054,0.0002895007,0.00011608323,0.001604319,0.0043009585,0.0000020502562,0.00000544388,0.00001255811,0.00011856017],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993644,0.0000399513,0.00014900915,0.0001222888,0.000101361744,0.00022303063],"domain_scores_gemma":[0.99962705,0.000005038245,0.00005094373,0.0001510259,0.000038247344,0.00012771066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020746149,0.00010761813,0.000088815934,0.000008574394,0.00031355955,0.00009236594,0.00025195532,0.000046946574,0.000035458546],"category_scores_gemma":[0.00006381262,0.000063188636,0.000058767237,0.00008330672,0.000057795965,0.0000028703055,0.00013656267,0.00018099869,0.000004375777],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100559155,0.000054687705,0.0077163284,0.000059169848,0.00033452138,0.00003962127,0.0014919863,0.0049112197,0.92751837,0.0013349258,0.051890217,0.004548411],"study_design_scores_gemma":[0.0028750105,0.0011294681,0.06060262,0.000034466688,0.00021040415,0.0031629107,0.003682011,0.0017163062,0.04953106,0.0020721133,0.8741526,0.0008310334],"about_ca_topic_score_codex":0.000010246381,"about_ca_topic_score_gemma":0.0000080247155,"teacher_disagreement_score":0.87798727,"about_ca_system_score_codex":0.000007402287,"about_ca_system_score_gemma":0.000035332865,"threshold_uncertainty_score":0.2576758},"labels":[],"label_agreement":null},{"id":"W3095381385","doi":"10.1111/pbi.13508","title":"Efficient multiplex genome editing by CRISPR/Cas9 in common wheat","year":2020,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Natural Science Foundation of China","keywords":"Biology; CRISPR; Multiplex; Genome editing; Cas9; Computational biology; Genome; Genetics; Gene","score_opus":0.00794379221917378,"score_gpt":0.2494875086640331,"score_spread":0.24154371644485934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3095381385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97131556,0.0046017827,0.01936788,0.0041933563,0.00021773178,0.000112358815,0.00007586948,0.000041083244,0.000074354306],"genre_scores_gemma":[0.99773145,0.00058908865,0.0008608784,0.0003776112,0.00033127045,0.0000040517825,0.00006950072,0.000020453439,0.000015674086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989071,0.00002901122,0.00030639078,0.00027313936,0.00010569139,0.00037867087],"domain_scores_gemma":[0.99961394,0.000010371924,0.00007773354,0.00015162105,0.000018832558,0.0001275199],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015546828,0.00016840611,0.00020126508,0.00009140729,0.000084731946,0.000023296463,0.00028389995,0.00035972736,0.000018550809],"category_scores_gemma":[0.000077819386,0.00016345429,0.00006117991,0.00012530002,0.000060645587,0.0000014629584,0.00013658484,0.0005502035,0.000011705138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040862345,0.000035794692,0.0015611192,0.000011591455,0.000024656807,0.000071399256,0.00007119904,0.0057677357,0.98865855,0.0000125727565,0.0019994206,0.0017451055],"study_design_scores_gemma":[0.0012318591,0.00039292077,0.0011089728,0.000029655836,0.000016134598,0.0010396737,0.00038532214,0.012255483,0.8868628,0.00001325213,0.0963105,0.0003534276],"about_ca_topic_score_codex":0.000008094154,"about_ca_topic_score_gemma":0.000019396906,"teacher_disagreement_score":0.10179574,"about_ca_system_score_codex":0.0000207566,"about_ca_system_score_gemma":0.000021416123,"threshold_uncertainty_score":0.66654724},"labels":[],"label_agreement":null},{"id":"W3095424764","doi":"10.3168/jds.2020-18700","title":"CRISPR-Cas9-mediated knockout of GCN2 reveals a critical role in sensing amino acid deprivation in bovine mammary epithelial cells","year":2020,"lang":"en","type":"article","venue":"Journal of Dairy Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Phosphorylation; Messenger RNA; Biology; Molecular biology; Integrated stress response; ATF4; Translational regulation; Translation (biology); Gene expression; Gene; Cell biology; Biochemistry; Chemistry; Transcription factor","score_opus":0.009854423242373758,"score_gpt":0.2829466456431098,"score_spread":0.27309222240073605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3095424764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9697412,0.0005288018,0.028829798,0.0006377113,0.00013895573,0.0000528593,0.000005540109,0.000002239482,0.0000628719],"genre_scores_gemma":[0.99223876,0.00006808866,0.0073562968,0.00019828409,0.00012666492,2.581115e-7,0.0000015247022,0.000006057571,0.0000040930204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886394,0.00003854635,0.0004534391,0.00018180476,0.00025453782,0.00020775007],"domain_scores_gemma":[0.9994631,0.000032330267,0.00011658462,0.00012830814,0.00013546603,0.00012421209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056625094,0.00008750844,0.00018010466,0.00014508731,0.000021603653,0.000019025245,0.0002596746,0.00006589307,0.0000030486246],"category_scores_gemma":[0.0010332095,0.000083561616,0.000049931405,0.00040380217,0.00011047588,0.000024776089,0.00010600709,0.00015833515,0.0000011642156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005917487,0.000025389076,0.0022387179,0.000022259905,0.0000025831714,0.00002759397,0.00023893875,0.00064669177,0.9949695,0.000007892558,0.000051791318,0.0017094899],"study_design_scores_gemma":[0.0004683027,0.0003260245,0.0254379,0.000052504707,0.0000049963237,0.00004383618,0.00014985881,0.004926405,0.9682305,0.00006367124,0.00020027607,0.00009574182],"about_ca_topic_score_codex":0.000006854657,"about_ca_topic_score_gemma":0.000007534518,"teacher_disagreement_score":0.026738994,"about_ca_system_score_codex":0.000020711548,"about_ca_system_score_gemma":0.0001647277,"threshold_uncertainty_score":0.3407544},"labels":[],"label_agreement":null},{"id":"W3095800501","doi":"10.1101/2020.10.27.357830","title":"Base editing strategy allows insertion of the A673T mutation in APP gene to prevent the development of Alzheimer’s disease","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Weston Brain Institute","keywords":"Amyloid precursor protein; Cytosine deaminase; HEK 293 cells; Gene; Mutation; Biology; Genetics; Alzheimer's disease; Molecular biology; Disease; Medicine; Genetic enhancement; Internal medicine","score_opus":0.016054128657520268,"score_gpt":0.2574902063717637,"score_spread":0.2414360777142434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3095800501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99007696,0.0012923024,0.007268863,0.00020575512,0.00030492875,0.00076614006,0.00006753968,0.000015514031,0.000001996317],"genre_scores_gemma":[0.9961498,0.00003548693,0.0033519955,0.00006720836,0.00019745325,0.00015392361,0.0000022637262,0.00004102897,8.795659e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984707,0.00008949922,0.0005473324,0.0004458309,0.00023849477,0.00020811806],"domain_scores_gemma":[0.9988269,0.00000968892,0.0002579419,0.0006205981,0.000163391,0.000121474004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000360873,0.00024634492,0.00022329474,0.00006086914,0.000051467337,0.000019953844,0.00037732066,0.00015112557,0.0000036521767],"category_scores_gemma":[0.00016187044,0.00020057213,0.00010504534,0.0002216712,0.00003950604,0.000003661777,0.00044345311,0.00020204665,0.0000015396334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002878215,0.00007701902,0.0013011263,0.00017475104,0.00008454666,0.0000024456563,0.000044066477,0.016187906,0.98202634,0.000013132749,0.0000324832,0.000027400094],"study_design_scores_gemma":[0.00014188809,0.00002687195,0.1560939,0.00015381201,0.000059785852,5.49898e-9,0.000010921963,0.00065050734,0.8424194,8.836622e-7,0.00026120836,0.00018085782],"about_ca_topic_score_codex":0.000017425158,"about_ca_topic_score_gemma":0.000017525947,"teacher_disagreement_score":0.15479276,"about_ca_system_score_codex":0.00003787666,"about_ca_system_score_gemma":0.0005560686,"threshold_uncertainty_score":0.8179094},"labels":[],"label_agreement":null},{"id":"W3096307756","doi":"10.1101/2020.10.29.360404","title":"Gene Drives Across Engineered Fitness Valleys: Modeling a Design to Prevent Drive Spillover","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene drive; Spillover effect; Population; Homing (biology); Computer science; Positive feedback; Control theory (sociology); Engineering; Biology; Gene; Ecology; Artificial intelligence; Economics; CRISPR; Electrical engineering; Genetics; Control (management)","score_opus":0.01636245730153704,"score_gpt":0.2644565412863944,"score_spread":0.24809408398485736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3096307756","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4865773,0.0014594549,0.5101658,0.00013122111,0.000603079,0.00079313386,0.00013713552,0.00013133383,0.0000015325872],"genre_scores_gemma":[0.94817144,0.00045632006,0.04956503,0.00025036815,0.0009869289,0.00032991508,0.000003204813,0.00022695486,0.000009813954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99665403,0.00009352347,0.00057398656,0.0015149814,0.0003527906,0.00081070693],"domain_scores_gemma":[0.99759245,0.00001776126,0.00015121144,0.0013482637,0.0003440872,0.0005462441],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003725261,0.0007848115,0.00060973165,0.00010556659,0.00012495316,0.00017276953,0.0008048207,0.00066588644,0.000011489355],"category_scores_gemma":[0.00025658618,0.00090581906,0.00027943653,0.0002769845,0.000045006353,0.000008475237,0.0012236339,0.00050675235,0.000040772895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004308206,0.0000675161,0.000050219514,0.00013383315,0.00022149035,0.000021740165,0.00004265274,0.25193048,0.74725,0.000007948949,0.00022750309,0.0000035037383],"study_design_scores_gemma":[0.00042075614,0.00015740217,0.000812516,0.0001836755,0.00009067739,5.739744e-8,0.0000086569935,0.034365572,0.9614211,0.0000014963639,0.0014422273,0.0010959059],"about_ca_topic_score_codex":0.000021737093,"about_ca_topic_score_gemma":0.0000021231037,"teacher_disagreement_score":0.46159416,"about_ca_system_score_codex":0.00010497346,"about_ca_system_score_gemma":0.00034493094,"threshold_uncertainty_score":0.9993392},"labels":[],"label_agreement":null},{"id":"W3097054553","doi":"10.1182/blood-2020-141412","title":"High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of <i>Hox/Meis</i> Gene Expression in Acute Myeloid Leukemia","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Hox gene; Epigenetics; Chromatin; Biology; Myeloid leukemia; Transcription factor; Cancer research; Genetics; Cell biology; Gene","score_opus":0.005918150406433932,"score_gpt":0.23077046393347936,"score_spread":0.22485231352704543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3097054553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887328,0.0011792108,0.00951882,0.00011098486,0.000087028944,0.00022308913,0.00003974488,0.000030910363,0.00007737681],"genre_scores_gemma":[0.978228,0.0002538453,0.02089995,0.00018847441,0.00025118756,0.000012108212,0.00007181698,0.000041336003,0.000053284424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985426,0.000056764366,0.00038889828,0.0004891789,0.00019533484,0.0003271949],"domain_scores_gemma":[0.99920917,0.000010904555,0.00009453368,0.00045124334,0.000055788492,0.00017836932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012304136,0.00023716135,0.00033356462,0.000049601775,0.000041736188,0.000008843552,0.00024079367,0.00022165882,0.0000096861],"category_scores_gemma":[0.000042361804,0.00024297024,0.00014834462,0.00017807147,0.00005940607,0.0000037176023,0.00020672452,0.00014264978,0.0000044744947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009434649,0.00006803115,0.004845302,0.00004630171,0.00007783773,0.000025233587,0.000117321266,0.0007588409,0.993042,0.000008913258,0.00062533095,0.00029054322],"study_design_scores_gemma":[0.002020536,0.00027144552,0.026226947,0.000031606873,0.00007538789,0.000012118244,0.00003436915,0.000028262257,0.97024894,0.00003475288,0.0007580699,0.00025758636],"about_ca_topic_score_codex":0.00006190767,"about_ca_topic_score_gemma":0.000033608147,"teacher_disagreement_score":0.02279308,"about_ca_system_score_codex":0.000014585913,"about_ca_system_score_gemma":0.00007777891,"threshold_uncertainty_score":0.9908039},"labels":[],"label_agreement":null},{"id":"W3097886583","doi":"10.3791/61693","title":"In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity","year":2020,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Cas9; Biology; Computational biology; Gene; Function (biology); Gene targeting; Trans-activating crRNA; Genetics","score_opus":0.025032899312372504,"score_gpt":0.42104016911042536,"score_spread":0.39600726979805284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3097886583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97418666,0.0009302701,0.024498006,0.0001305391,0.000101805956,0.000130121,0.0000036951371,0.000003072098,0.000015810181],"genre_scores_gemma":[0.99441296,0.00009610714,0.0046068225,0.00065613113,0.00014998701,0.0000046015602,0.000002425396,0.000020023257,0.000050958104],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900204,0.0000724355,0.00036687218,0.00019083256,0.00018181815,0.00018598615],"domain_scores_gemma":[0.99959093,0.000009844717,0.000087420674,0.000084752704,0.000059104368,0.00016793511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025125773,0.00013614235,0.00022676233,0.00009401321,0.000020288564,0.000022791952,0.000094235744,0.000079132566,0.000026263673],"category_scores_gemma":[0.000116450035,0.00013470055,0.000053342177,0.00011604996,0.000011941249,0.000010229575,0.000078978315,0.00010917769,0.0000014200638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00082720874,0.00006145519,0.0011015941,0.000009318301,0.000030497902,0.000039975912,0.00067617855,0.007876206,0.9882056,9.3054837e-7,0.00034297927,0.00082807214],"study_design_scores_gemma":[0.002507575,0.00077801995,0.00074448704,0.000020619973,0.0000115121975,0.000030904892,0.00031465193,0.003024332,0.98905486,0.0000031847133,0.003357992,0.00015183845],"about_ca_topic_score_codex":0.0000409961,"about_ca_topic_score_gemma":0.00001751579,"teacher_disagreement_score":0.020226264,"about_ca_system_score_codex":0.000023472001,"about_ca_system_score_gemma":0.000025135809,"threshold_uncertainty_score":0.54929286},"labels":[],"label_agreement":null},{"id":"W3098075819","doi":"10.3390/life10110295","title":"Genome Editing by CRISPR-Cas: A Game Change in the Genetic Manipulation of Chlamydomonas","year":2020,"lang":"en","type":"review","venue":"Life","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Mitacs; Canada Research Chairs","keywords":"CRISPR; Genome editing; Chlamydomonas reinhardtii; Transcription activator-like effector nuclease; Biology; Computational biology; Chlamydomonas; Zinc finger nuclease; Cas9; Genome; Genetics; Gene","score_opus":0.03921604636329762,"score_gpt":0.34832466329264544,"score_spread":0.3091086169293478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098075819","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00038821768,0.9967696,0.0019068065,0.000055817618,0.00013813877,0.00058535364,0.00005645056,0.0000071505924,0.000092477094],"genre_scores_gemma":[0.01804828,0.9795695,0.0001217244,0.00015626427,0.0014296786,0.00016127298,0.0004449552,0.00004841601,0.000019940366],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99875873,0.00008637334,0.00045871641,0.00032914415,0.00015263635,0.00021436889],"domain_scores_gemma":[0.999388,0.000021067295,0.0001791936,0.00033041084,0.000020227873,0.00006109405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013673725,0.00025949272,0.0005458667,0.000053089083,0.000017680193,0.000016133215,0.00032936723,0.00024035292,0.000012943985],"category_scores_gemma":[0.000077746976,0.00020746698,0.00020358893,0.0001736984,0.000023327697,0.000001707212,0.00009780963,0.00018045999,0.000009090198],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019310784,0.00015139995,0.00023425903,0.02090631,0.0003841038,0.000053135696,0.0015996459,0.00015745257,0.0064110127,0.000042814147,0.002156482,0.96788406],"study_design_scores_gemma":[0.00011937728,0.00007490359,0.0004375766,0.00045609273,0.00012351896,0.000020005977,0.000032835535,0.000065886634,0.00013989303,0.0000021674755,0.9983103,0.00021740349],"about_ca_topic_score_codex":0.000029580644,"about_ca_topic_score_gemma":0.000014669531,"teacher_disagreement_score":0.99615383,"about_ca_system_score_codex":0.000013051385,"about_ca_system_score_gemma":0.000046216686,"threshold_uncertainty_score":0.84602576},"labels":[],"label_agreement":null},{"id":"W3098350592","doi":"10.1186/s13578-020-00496-y","title":"Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology","year":2020,"lang":"en","type":"letter","venue":"Cell & Bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Transgenic Science and Technology Program; National Swine Industry Technology System; Fundamental Research Funds for the Central Universities","keywords":"Lactoferrin; Colostrum; Biology; Casein; CRISPR; Lactation; Genetically modified organism; Gene; Food science; Immunology; Genetics; Antibody","score_opus":0.01088258537585482,"score_gpt":0.2579619568912109,"score_spread":0.24707937151535606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098350592","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986326,0.0014222503,0.007685685,0.0037695656,0.00044070889,0.00024730526,0.000047992104,0.000009105863,0.000051380288],"genre_scores_gemma":[0.9949871,0.00037048032,0.0018142659,0.0023205213,0.00038217628,0.000007817807,0.000034398025,0.000030782736,0.00005249507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834156,0.00005688094,0.00044635267,0.0005575378,0.0001907765,0.00040686497],"domain_scores_gemma":[0.99920654,0.000033046068,0.00020712777,0.00048674707,0.000038877028,0.000027638836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016567264,0.00026707476,0.0003939444,0.00024967376,0.000041622854,0.000018846002,0.0005733967,0.00046661193,0.000012369986],"category_scores_gemma":[0.00004058123,0.00023761853,0.00010167876,0.00047943895,0.00036252238,0.000005300138,0.0002987456,0.0004940022,0.0000012446733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018011133,0.00002316734,0.0004895108,0.0001394751,0.000004121094,0.000027130081,0.00019596754,0.00020224242,0.9977017,4.0605363e-7,0.0010659877,0.00013227694],"study_design_scores_gemma":[0.00021895775,0.00011291424,0.00032970763,0.00007990542,0.000009723049,0.000013253089,0.00009009074,0.00025721584,0.98671824,0.000011750542,0.01192356,0.00023466295],"about_ca_topic_score_codex":0.000079951584,"about_ca_topic_score_gemma":0.000118304495,"teacher_disagreement_score":0.010983445,"about_ca_system_score_codex":0.000030608946,"about_ca_system_score_gemma":0.00012779057,"threshold_uncertainty_score":0.9689802},"labels":[],"label_agreement":null},{"id":"W3099399169","doi":"10.1101/677203","title":"Perturbing proteomes at single residue resolution using base editing","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Université Laval","keywords":"Computational biology; CRISPR; Genome editing; Proteome; RNA editing; Guide RNA; Biology; Gene; Cytidine; Genetics; Context (archaeology); Genome; Cytidine deaminase; Cas9; RNA; Enzyme","score_opus":0.014548844332998329,"score_gpt":0.2436064466724995,"score_spread":0.22905760233950118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3099399169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9703627,0.0035020655,0.023454748,0.00006924264,0.001509974,0.000817269,0.000121381185,0.0001386478,0.000023964436],"genre_scores_gemma":[0.98528457,0.000117471776,0.0122582195,0.00009580357,0.0019392149,0.00007910492,0.0000033290655,0.00019052786,0.00003174269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972075,0.00010626087,0.0004891068,0.001186252,0.00032878967,0.0006820571],"domain_scores_gemma":[0.99781656,0.000020410238,0.00031903115,0.001337419,0.00029960464,0.00020699696],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047983017,0.00057772634,0.0004304943,0.00017032307,0.00021702703,0.00013782611,0.00041139766,0.0007519991,0.000035531786],"category_scores_gemma":[0.00034590095,0.0006702866,0.00020607188,0.0001701356,0.000076276425,0.000010182345,0.0010807866,0.0004780494,0.00003441349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028684586,0.000045989287,0.0025440336,0.00038720877,0.00008628283,0.000015559286,0.000006722622,0.012402776,0.98404074,0.000008104575,0.00043256007,0.0000013707381],"study_design_scores_gemma":[0.00038516163,0.00008718777,0.004427498,0.00044647267,0.00008233935,1.2085074e-7,0.000004809074,0.006307446,0.98328066,3.594433e-7,0.0042047626,0.0007731705],"about_ca_topic_score_codex":0.00004336055,"about_ca_topic_score_gemma":0.0000046675623,"teacher_disagreement_score":0.0149218775,"about_ca_system_score_codex":0.00030888,"about_ca_system_score_gemma":0.00030448116,"threshold_uncertainty_score":0.99957484},"labels":[],"label_agreement":null},{"id":"W3100036770","doi":"10.1101/197962","title":"Allele-specific CRISPR/Cas9 genome editing of the single-base P23H mutation for rhodopsin associated dominant retinitis pigmentosa","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Eye Institute; Charles A. King Trust; Research to Prevent Blindness","keywords":"Retinitis pigmentosa; Allele; Biology; CRISPR; Genetics; Mutant; Cas9; Genome editing; Gene silencing; Mutation; Rhodopsin; Gene; Retinal","score_opus":0.018721759486132028,"score_gpt":0.2558538580542939,"score_spread":0.23713209856816186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3100036770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96011037,0.0030929495,0.03226958,0.00023411025,0.0019030643,0.0013289796,0.0009835637,0.00005775599,0.000019633206],"genre_scores_gemma":[0.9943667,0.00031296315,0.0038290136,0.000048819522,0.0010546122,0.0002113712,0.000015332973,0.00014229672,0.000018875879],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974662,0.000120394216,0.0006581664,0.00088662066,0.00031823208,0.0005503982],"domain_scores_gemma":[0.99668324,0.000048901366,0.0009239884,0.0015473977,0.0006571788,0.00013926931],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007939342,0.000504998,0.00051506364,0.00010160136,0.00030450782,0.0001572974,0.0007721308,0.00063337956,0.0000103898865],"category_scores_gemma":[0.00089622405,0.0004953254,0.00035928612,0.000117633375,0.00016041883,0.000009104509,0.0005407013,0.00036150106,0.0000027423764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050193816,0.00011240602,0.00046028965,0.0002607892,0.00017479387,0.000008966908,0.000016983193,0.00060110376,0.99770933,0.000032971922,0.00056026335,0.000011880636],"study_design_scores_gemma":[0.00091777707,0.00014319037,0.018046832,0.0003085138,0.00013209034,7.9240394e-8,0.0000101050055,0.00023050132,0.9690781,0.0000029162686,0.010576055,0.0005538307],"about_ca_topic_score_codex":0.000021155009,"about_ca_topic_score_gemma":0.000010437237,"teacher_disagreement_score":0.034256347,"about_ca_system_score_codex":0.00013386719,"about_ca_system_score_gemma":0.0002639271,"threshold_uncertainty_score":0.99974984},"labels":[],"label_agreement":null},{"id":"W3100746197","doi":"10.1016/j.neurobiolaging.2020.11.007","title":"Replication assessment of NUS1 variants in Parkinson's disease","year":2020,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institutes of Health","keywords":"Nonsynonymous substitution; Minor allele frequency; Genome-wide association study; Genetic association; Genetics; Biology; Exome; Population; LRRK2; Allele frequency; Allele; Parkinson's disease; Disease; Exome sequencing; Medicine; Phenotype; Single-nucleotide polymorphism; Mutation; Gene; Genotype; Genome; Internal medicine","score_opus":0.011597955132498934,"score_gpt":0.30775192820330605,"score_spread":0.2961539730708071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3100746197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950632,0.00017461012,0.003936051,0.0005074631,0.000048036254,0.00008090069,0.000010118017,0.0000050837493,0.00017452867],"genre_scores_gemma":[0.9987691,0.000093129696,0.00084843417,0.00019672037,0.00003858136,0.000005036682,0.000035458786,0.0000072578327,0.0000062857534],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999438,0.00003422187,0.00016487755,0.00024242877,0.000028870538,0.0000916382],"domain_scores_gemma":[0.99963444,0.000009717292,0.000060016653,0.00023439633,0.000019794283,0.000041616073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007538487,0.00006172402,0.00010745373,0.000024865505,0.0000076202696,0.0000012036373,0.000104728286,0.00003835852,0.0000052999703],"category_scores_gemma":[0.000054555934,0.00006498454,0.000034134177,0.00006231889,0.000031659674,0.0000012128359,0.000059550086,0.000050118262,3.2726592e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018203382,0.00002405557,0.14661554,0.000046042336,0.000008610484,0.0000013940555,0.000029959461,0.0027510647,0.8498888,0.00004616633,0.00008081019,0.0004893375],"study_design_scores_gemma":[0.00031594126,0.00014140626,0.7186352,0.000013759844,0.000009115893,0.0000012534143,0.000014050249,0.0013579591,0.27707565,0.0000133824715,0.0023460898,0.00007621058],"about_ca_topic_score_codex":0.0000042761453,"about_ca_topic_score_gemma":0.0000015842488,"teacher_disagreement_score":0.57281315,"about_ca_system_score_codex":0.000002365511,"about_ca_system_score_gemma":0.000029288854,"threshold_uncertainty_score":0.26499927},"labels":[],"label_agreement":null},{"id":"W3101114845","doi":"10.1186/s13059-020-02193-y","title":"A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila","year":2020,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Institute of Genetics; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; CRISPR; Computational biology; RNA editing; Gene; Endonuclease; RNA; microRNA; Genetics","score_opus":0.02297124129367709,"score_gpt":0.31702903389229464,"score_spread":0.29405779259861753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3101114845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8604484,0.0010741941,0.13592052,0.0013295473,0.00020302406,0.0004740424,0.00007958188,0.000027418033,0.0004432426],"genre_scores_gemma":[0.9965269,0.000022571301,0.0018673519,0.00071130635,0.00034613028,0.000051209383,0.00042440786,0.00001880522,0.00003129244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992369,0.000021018705,0.0001759199,0.00031004523,0.000029074305,0.00022708789],"domain_scores_gemma":[0.9997097,0.000013590543,0.000034017645,0.00015044467,0.000027741737,0.00006450907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007525851,0.000118462274,0.00013549182,0.000038256712,0.000026966529,0.000006620391,0.0001236502,0.00015153873,0.00002668546],"category_scores_gemma":[0.000067975125,0.00012598955,0.00006778858,0.00007328988,0.00002515101,0.0000014138186,0.000041477368,0.00005176197,0.000011076638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119027885,0.000015169873,0.0021210671,0.000029090936,0.00001397028,0.0000012572797,0.00005852753,0.0048974426,0.9914802,0.000128456,0.00018366135,0.00095218],"study_design_scores_gemma":[0.0051425877,0.0025247836,0.047607467,0.00001335095,0.000047346748,0.0000071002128,0.00013015216,0.0186674,0.535578,0.0005836165,0.3887216,0.000976575],"about_ca_topic_score_codex":0.000008350896,"about_ca_topic_score_gemma":0.0000126622845,"teacher_disagreement_score":0.45590213,"about_ca_system_score_codex":0.000013303064,"about_ca_system_score_gemma":0.00003505257,"threshold_uncertainty_score":0.51377046},"labels":[],"label_agreement":null},{"id":"W3101678791","doi":"10.1101/276188","title":"Type I-F CRISPR-Cas distribution and array dynamics in <i>Legionella pneumophila</i>","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Legionella pneumophila; Biology; Plasmid; Computational biology; Genetics; DNA; Bacteria; Gene","score_opus":0.0070191463955224425,"score_gpt":0.24117059717722691,"score_spread":0.23415145078170446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3101678791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798885,0.0020526247,0.016161505,0.00014929219,0.0010486023,0.00036422734,0.00025068125,0.0000652243,0.000019369518],"genre_scores_gemma":[0.99666923,0.0013482358,0.0011279252,0.00009103914,0.0006150077,0.000041588457,0.0000133467265,0.00008657634,0.000007043153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981251,0.0000483288,0.00036225363,0.0008667613,0.00016397268,0.00043362353],"domain_scores_gemma":[0.99858767,0.000010200494,0.00013790636,0.00083963235,0.00024745445,0.00017715993],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029727857,0.00043152552,0.0003373316,0.00009398491,0.00007368996,0.000089769215,0.00028339212,0.00062791863,0.000002698255],"category_scores_gemma":[0.000121908444,0.00049996097,0.00008022707,0.00022552768,0.0001240869,0.000005645371,0.00036845464,0.00039295678,0.000013181813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050937415,0.00006859673,0.018013932,0.00022362922,0.00006700845,0.00001672578,0.000004930884,0.0001859141,0.980461,0.00013165969,0.0007730652,0.0000026046373],"study_design_scores_gemma":[0.0005315798,0.0001738224,0.07991827,0.00022202103,0.00007260391,1.6666354e-7,0.000006171593,0.0014095205,0.9047801,0.0000065038803,0.0118796,0.0009996535],"about_ca_topic_score_codex":0.000036856927,"about_ca_topic_score_gemma":0.00002895819,"teacher_disagreement_score":0.07568091,"about_ca_system_score_codex":0.00015663475,"about_ca_system_score_gemma":0.00017971982,"threshold_uncertainty_score":0.9997452},"labels":[],"label_agreement":null},{"id":"W3101892755","doi":"10.1016/j.jmb.2020.11.009","title":"B Cell Subsets and Mechanisms Involved in Immune Regulation in Health and Disease","year":2020,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Nuclease; DNA; Cas9; Binding site; Biology; Mutagenesis; Genetics; Computational biology; Cell biology; Chemistry; Mutation; Gene","score_opus":0.006584821213064303,"score_gpt":0.2848834044608962,"score_spread":0.2782985832478319,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3101892755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91701066,0.015854165,0.0652026,0.0018060693,0.000037751775,0.00007777865,0.0000021673009,0.0000012953194,0.0000074873824],"genre_scores_gemma":[0.99643356,0.0008737902,0.0020256785,0.0006141313,0.000028061142,0.0000011816176,0.000012819191,0.0000082767965,0.000002520248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933857,0.00007927397,0.00028632127,0.00013444533,0.00003864266,0.00012275222],"domain_scores_gemma":[0.99961776,0.00000587213,0.000102250866,0.00006475263,0.000020474177,0.0001889188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018908296,0.00008017503,0.00016174167,0.00006320679,0.000009741093,0.0000053841463,0.000055738776,0.000068718655,0.0000017085541],"category_scores_gemma":[0.00010094566,0.000076705,0.000030362156,0.000060033854,0.000023910157,0.000002268808,0.000049602586,0.00009312197,1.6339013e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012961063,0.000018065586,0.0049574687,0.00004722754,0.000006997997,0.000020134952,0.000077291195,0.0004399444,0.99336183,0.00025307073,0.000025658062,0.0006626958],"study_design_scores_gemma":[0.0069389497,0.003355814,0.08745885,0.00016768515,0.000028670873,0.0000889511,0.0005407067,0.0035367268,0.8835283,0.010640961,0.0031204505,0.0005939284],"about_ca_topic_score_codex":0.000007183553,"about_ca_topic_score_gemma":0.0000063934617,"teacher_disagreement_score":0.10983352,"about_ca_system_score_codex":0.0000074517084,"about_ca_system_score_gemma":0.000069308146,"threshold_uncertainty_score":0.3127939},"labels":[],"label_agreement":null},{"id":"W3102200920","doi":"10.1101/248179","title":"Homology Directed Repair by Cas9:Donor Co-localization in Mammalian Cells","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Occupational Cancer Research Centre; William Osler Health System","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Genome editing; CRISPR; Cas9; Homology directed repair; HEK 293 cells; DNA; Indel; Biology; Computational biology; Colocalization; Gene; Cell biology; Molecular biology; DNA repair; Genetics; Nucleotide excision repair","score_opus":0.006106561764290414,"score_gpt":0.24024487131864383,"score_spread":0.2341383095543534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3102200920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844533,0.0026915888,0.0103032235,0.00005386865,0.0011804278,0.0006297401,0.00036146777,0.0003007983,0.000025579284],"genre_scores_gemma":[0.9958831,0.000510561,0.0025200876,0.00020496438,0.00054706266,0.00014385866,0.000011162276,0.00014563567,0.000033560143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99745345,0.00014264593,0.00052160164,0.0011227384,0.00018200924,0.0005775277],"domain_scores_gemma":[0.9981999,0.000014103497,0.00019587824,0.0011483572,0.00024107523,0.00020069686],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037265528,0.0005120757,0.0004361487,0.0001861856,0.00007955556,0.000059683614,0.00040628726,0.00095512357,0.000046419467],"category_scores_gemma":[0.00011728425,0.00061384076,0.00015664817,0.0002623526,0.00013577795,0.000005248301,0.0003357354,0.0003739656,0.000038283502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003627752,0.000094550356,0.0070839017,0.00018224282,0.000080595026,0.000027406295,0.000006273691,0.0005507611,0.9777476,0.00000710839,0.014181972,0.0000012816749],"study_design_scores_gemma":[0.0004556132,0.00011709509,0.008852302,0.0000760577,0.00004370957,5.2061036e-8,0.0000018232325,0.0013538249,0.93162537,4.596143e-7,0.056782518,0.00069119304],"about_ca_topic_score_codex":0.00013660785,"about_ca_topic_score_gemma":0.000029970632,"teacher_disagreement_score":0.04612228,"about_ca_system_score_codex":0.00010828607,"about_ca_system_score_gemma":0.00024396472,"threshold_uncertainty_score":0.9996313},"labels":[],"label_agreement":null},{"id":"W3102748721","doi":"10.1007/s11427-020-1800-5","title":"Generating broad-spectrum tolerance to ALS-inhibiting herbicides in rice by base editing","year":2020,"lang":"en","type":"article","venue":"Science China Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Acetolactate synthase; Biology; Genetics; Gene; Missense mutation; Genome editing; Mutant; Biotechnology; Genome; Mutation","score_opus":0.01018846487331018,"score_gpt":0.2876194040307041,"score_spread":0.2774309391573939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3102748721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824591,0.0010125933,0.011234858,0.004004484,0.000255873,0.0001443521,0.0000062592553,0.000027218384,0.00085526326],"genre_scores_gemma":[0.98948526,0.00002350468,0.007447847,0.0024081408,0.00058814505,0.000010649325,0.0000024563017,0.000009831845,0.000024134713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777,0.00003113611,0.00028359267,0.0008314896,0.00045467739,0.0006290766],"domain_scores_gemma":[0.99936384,0.000016459035,0.000068830464,0.00015871644,0.00003479691,0.00035734795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010900338,0.00017190255,0.00015110016,0.00009396124,0.00047360527,0.00016335055,0.00067749916,0.00004176892,0.000011430803],"category_scores_gemma":[0.0011681038,0.00016163127,0.000039496743,0.001463531,0.0003646009,0.00003853725,0.00026798967,0.00012010087,0.000008856927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000031864067,0.000008792922,0.002732404,0.000010986186,8.087863e-7,0.0000016319942,0.00048149386,0.047263626,0.94801706,0.000020728696,0.0006722127,0.00078709284],"study_design_scores_gemma":[0.00016777431,0.00023381782,0.0030638364,0.00004512552,0.0000017562754,0.000005549928,0.0009499113,0.050723594,0.9438133,0.000020632793,0.0006724295,0.00030225105],"about_ca_topic_score_codex":0.00010436654,"about_ca_topic_score_gemma":0.000039795705,"teacher_disagreement_score":0.0070261913,"about_ca_system_score_codex":0.00001864495,"about_ca_system_score_gemma":0.00021686165,"threshold_uncertainty_score":0.6591132},"labels":[],"label_agreement":null},{"id":"W3104647282","doi":"10.1101/185298","title":"Editing of the Human TRIM5 Gene to Introduce Mutations with the Potential to Inhibit HIV-1","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Broad Institute","keywords":"CRISPR; Biology; Genome editing; Gene; Transfection; Genetics; HEK 293 cells; Cas9; Mutation; Plasmid; Allele; DNA; Capsid; Virology","score_opus":0.006721402485375926,"score_gpt":0.24388583305185624,"score_spread":0.23716443056648032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3104647282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.977549,0.00025717632,0.019302769,0.0013174197,0.0006202729,0.00073118083,0.00018190971,0.000028467482,0.000011794088],"genre_scores_gemma":[0.9946465,0.000011379438,0.0033327765,0.00017825456,0.0015844791,0.00013999679,0.0000014265357,0.00007494733,0.000030268791],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841714,0.00005652319,0.0002922609,0.00063326757,0.00026428312,0.0003365316],"domain_scores_gemma":[0.99746805,0.000007606715,0.00024003552,0.0017760568,0.00036326156,0.00014496631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003388518,0.0003230751,0.00026337706,0.00007813673,0.0003418181,0.00012041161,0.00090487365,0.00021607544,0.0000057216876],"category_scores_gemma":[0.00019227379,0.00023477248,0.00012839957,0.00015947763,0.00010835602,0.0000039741044,0.00089372485,0.0003239822,0.000007739734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014092092,0.000026696554,0.00075352995,0.000053445823,0.00009235732,0.000002934824,0.000018906714,0.008816362,0.98885626,0.00002959938,0.0013332288,0.000002606823],"study_design_scores_gemma":[0.00023601264,0.000069563925,0.037168536,0.00011542865,0.000093854214,5.8189922e-8,0.000008758967,0.000046686815,0.9560426,4.0942376e-7,0.005911135,0.00030697003],"about_ca_topic_score_codex":0.00003205261,"about_ca_topic_score_gemma":0.000015919928,"teacher_disagreement_score":0.036415007,"about_ca_system_score_codex":0.000035334477,"about_ca_system_score_gemma":0.00023226798,"threshold_uncertainty_score":0.9573744},"labels":[],"label_agreement":null},{"id":"W3105502005","doi":"10.1038/s41467-020-19602-2","title":"A translational program that suppresses metabolism to shield the genome","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Bioinformatics Solutions (Canada); Hospital for Sick Children","funders":"National Institute of General Medical Sciences; U.S. Department of Health and Human Services; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; Sylvester Comprehensive Cancer Center, University of Miami Health Systems","keywords":"mTORC1; Cell biology; Biology; Translation (biology); Regulator; Genome; Translational regulation; Protein biosynthesis; Messenger RNA; Genetics; Gene; Phosphorylation","score_opus":0.022078381921513582,"score_gpt":0.33931113511060723,"score_spread":0.31723275318909366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3105502005","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23152441,0.20452668,0.05819967,0.48216537,0.00061907375,0.00409016,0.00050505303,0.0004022708,0.017967314],"genre_scores_gemma":[0.9849069,0.00040348517,0.011666878,0.0025227475,0.00015019352,0.00010252558,0.0001941323,0.000012199597,0.000040910076],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995653,0.000032862685,0.000081500504,0.0001316605,0.00008400336,0.000104694765],"domain_scores_gemma":[0.9991527,0.000027062439,0.00001582576,0.0006918826,0.00004262815,0.00006987136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054858276,0.00007866677,0.00006181682,0.000013053856,0.0001179253,0.000028660354,0.0007442832,0.00011459814,0.000014047462],"category_scores_gemma":[0.000067279,0.0000614019,0.000058679358,0.00012925455,0.000038199672,0.0000021024048,0.00018378808,0.00026740492,0.00000752812],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009127289,0.000266051,0.001898522,0.000037781596,0.0003434393,9.490393e-7,0.0039016127,0.0041615344,0.92815363,0.009529201,0.027392363,0.02422366],"study_design_scores_gemma":[0.000102315105,0.000033062486,0.011254958,0.0000017943581,0.000021265698,0.000002320307,0.00008110222,0.00023429435,0.021401292,0.000021701026,0.96675086,0.00009506011],"about_ca_topic_score_codex":0.0000021819005,"about_ca_topic_score_gemma":0.00006352817,"teacher_disagreement_score":0.9393585,"about_ca_system_score_codex":0.0000015414513,"about_ca_system_score_gemma":0.000023643908,"threshold_uncertainty_score":0.25038967},"labels":[],"label_agreement":null},{"id":"W3107017081","doi":"10.3389/fgeed.2020.605768","title":"Precision Genome Engineering Through Cytidine Base Editing in Rapeseed (Brassica napus. L)","year":2020,"lang":"en","type":"article","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"Rapeseed; Genome editing; Biology; Cytidine; Genetics; Gene; Allele; Genome; Base (topology); Computational biology; Biotechnology; Agronomy; Mathematics; Biochemistry","score_opus":0.007419257740380537,"score_gpt":0.23851663132554757,"score_spread":0.23109737358516702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107017081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6369325,0.0060317274,0.352501,0.00062136946,0.002529003,0.00049228146,0.000041846168,0.00008239774,0.00076787797],"genre_scores_gemma":[0.9543794,0.00018480023,0.0406457,0.00022199783,0.0042579547,0.00003785975,0.0001641672,0.00007245308,0.00003567739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980314,0.000038584192,0.00050590147,0.0006172008,0.00020944099,0.0005974755],"domain_scores_gemma":[0.9994383,0.0000235856,0.0000947534,0.0002583974,0.00003748352,0.00014749421],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031773376,0.0002944289,0.000342428,0.000134538,0.00005658612,0.00003998211,0.000321599,0.00019735722,0.000020366482],"category_scores_gemma":[0.00049960084,0.00034555118,0.00010110255,0.00041370775,0.000029612307,0.00002005954,0.00022349147,0.00035413852,0.0000053516255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050613202,0.0000345089,0.0064801117,0.00012909235,0.00003896921,0.000053482938,0.0011344613,0.119918466,0.8690499,0.0000077755185,0.001463595,0.0016389913],"study_design_scores_gemma":[0.0077950316,0.0009369625,0.032793164,0.0005182249,0.00008523262,0.000055560875,0.0068077417,0.18025193,0.4814272,0.00012923576,0.28597698,0.00322275],"about_ca_topic_score_codex":0.000008767136,"about_ca_topic_score_gemma":0.000006745569,"teacher_disagreement_score":0.38762274,"about_ca_system_score_codex":0.00007570973,"about_ca_system_score_gemma":0.000041170275,"threshold_uncertainty_score":0.9998996},"labels":[],"label_agreement":null},{"id":"W3107086497","doi":"10.9734/ajb2t/2020/v6i330083","title":"Update of Regulatory Options of New Breeding Techniques and Biosafety Approaches among Selected Countries: A Review","year":2020,"lang":"en","type":"review","venue":"Asian Journal of Biotechnology and Bioresource Technology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Zinc finger nuclease; Genome editing; Biology; Transcription activator-like effector nuclease; Biotechnology; CRISPR; Computational biology; Genome; Genetics; Gene","score_opus":0.01366526870072483,"score_gpt":0.277138917210022,"score_spread":0.26347364850929716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107086497","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011243053,0.994886,0.0011541405,0.0022778406,0.000034525037,0.00041354058,0.00003554317,0.00005265385,0.000021447258],"genre_scores_gemma":[0.006538377,0.9878919,0.0053798337,0.00001729807,0.00008919848,0.000008514294,0.000017817458,0.000043587064,0.0000134776],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99793494,0.0000627972,0.0011878597,0.00041343638,0.00012873865,0.00027224526],"domain_scores_gemma":[0.99797946,0.000017605089,0.0013194862,0.00044731644,0.00012388629,0.000112256086],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003657192,0.00042441476,0.0018348275,0.00079961953,0.00005092395,0.000006672726,0.0005664337,0.0018774642,0.0000042954384],"category_scores_gemma":[0.00021269648,0.00035702053,0.000253387,0.00090290385,0.0011934249,0.0000068719005,0.00036462155,0.0007737987,3.6565112e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027338043,0.00003162361,0.0000661276,0.009501004,0.00061062165,0.000026576854,0.00003059621,2.1732765e-7,0.0040236446,0.00088783074,0.00061440794,0.98418003],"study_design_scores_gemma":[0.00030655297,0.0011915943,0.000022213022,0.0127289705,0.0010271388,0.0027726518,0.00016915565,0.0000017598106,0.04833339,0.00008712324,0.93298185,0.00037760107],"about_ca_topic_score_codex":0.000001475225,"about_ca_topic_score_gemma":0.0000018040784,"teacher_disagreement_score":0.98380244,"about_ca_system_score_codex":0.000016741977,"about_ca_system_score_gemma":0.00023671838,"threshold_uncertainty_score":0.9998882},"labels":[],"label_agreement":null},{"id":"W3107606441","doi":"10.1016/j.tibtech.2020.10.011","title":"Impacts on International Research Collaborations from DSI/ABS Uncertainty","year":2020,"lang":"en","type":"review","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; University of Saskatchewan","funders":"","keywords":"Intellectual property; Resource (disambiguation); Digitization; Data sharing; Genetic resources; Data science; Business; Biology; Biotechnology; Political science; Computer science; Telecommunications","score_opus":0.0694272159762888,"score_gpt":0.44940995637868614,"score_spread":0.3799827404023973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107606441","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018651062,0.9950728,0.00013307382,0.0013978649,0.00047691882,0.0002017216,0.0005114821,0.000053568485,0.0019660536],"genre_scores_gemma":[0.002159881,0.9944277,0.0004102723,0.00003951105,0.00039136875,0.000088616165,0.0019322552,0.000046368317,0.00050405896],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983217,0.000081009144,0.00038270277,0.0006729645,0.00018358268,0.00035800156],"domain_scores_gemma":[0.999138,0.000055248718,0.000084452535,0.00059495354,0.000054609467,0.000072750176],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016782469,0.0002958638,0.00059377303,0.0010158581,0.000046951413,0.000028182923,0.00069239666,0.0012103609,0.00009516141],"category_scores_gemma":[0.00023494875,0.00027638552,0.00015108746,0.001314275,0.00013677395,0.0000014901419,0.00033533736,0.0008386762,0.000066521156],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021548398,0.00005355505,0.0000044294284,0.00010980759,0.00014613781,0.000032726144,0.000017973867,0.0000707095,0.0012725437,0.00086199737,0.0055816593,0.9918269],"study_design_scores_gemma":[0.0002285599,0.00021374319,0.000009262287,0.0004287082,0.000028567472,0.000008764945,0.000024041501,0.000036254773,0.0016903083,0.00008007327,0.9970167,0.00023496166],"about_ca_topic_score_codex":0.000066577755,"about_ca_topic_score_gemma":0.0004078119,"teacher_disagreement_score":0.99159193,"about_ca_system_score_codex":0.00011553766,"about_ca_system_score_gemma":0.00014291104,"threshold_uncertainty_score":0.9999688},"labels":[],"label_agreement":null},{"id":"W3107924035","doi":"10.1016/j.omtm.2020.11.014","title":"CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Gilead Sciences","keywords":"cccDNA; Virology; Hepatitis B virus; Cas9; Entecavir; Biology; Adeno-associated virus; Genetic enhancement; Virus; Genome editing; CRISPR; Plasmid; Gene; Recombinant DNA; Vector (molecular biology); Genetics; Lamivudine; HBsAg","score_opus":0.04722707968031607,"score_gpt":0.43258368360056737,"score_spread":0.3853566039202513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107924035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5973251,0.0018590422,0.40014583,0.00015149178,0.00017249867,0.0002453473,0.0000036916088,0.000019950361,0.00007704035],"genre_scores_gemma":[0.53657466,0.0019819194,0.45949107,0.0015628417,0.00020786613,0.000043302338,0.00006699453,0.000055538647,0.000015772821],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99692804,0.000628766,0.0012118656,0.00063426717,0.0002245509,0.00037249128],"domain_scores_gemma":[0.9989958,0.00012786883,0.00020579303,0.00033661706,0.0001340602,0.00019987267],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014419374,0.00028895307,0.0005480884,0.000056872494,0.000042656382,0.00001831533,0.00034933613,0.00028755414,0.000060453356],"category_scores_gemma":[0.0009309658,0.0002943535,0.00022577566,0.00025096542,0.00008147434,0.00000384333,0.00021317949,0.00029527728,0.0000081006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014421497,0.00013674477,0.0040130457,0.000028314069,0.00016822972,0.000020283582,0.00018556227,0.00024073476,0.9132506,0.000011757332,0.000056160487,0.08174434],"study_design_scores_gemma":[0.0018959182,0.000398884,0.029288407,0.000027234863,0.000014349072,0.000003332509,0.000012348436,0.00036092303,0.9439744,0.00003559021,0.023666449,0.0003221758],"about_ca_topic_score_codex":0.000043893513,"about_ca_topic_score_gemma":0.000046702608,"teacher_disagreement_score":0.081422165,"about_ca_system_score_codex":0.000025932155,"about_ca_system_score_gemma":0.00021637071,"threshold_uncertainty_score":0.9999509},"labels":[],"label_agreement":null},{"id":"W3108031137","doi":"10.1101/2020.11.23.391771","title":"The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"York University; Sidney Kimmel Foundation; Melanoma Research Alliance; National Cancer Institute; Advanced Research Projects Agency; National Institutes of Health; National Institute of General Medical Sciences; Cancer Research Institute","keywords":"Biology; Psychological repression; Gene; Transcription factor; H3K4me3; Embryonic stem cell; Cell biology; Cellular differentiation; CRISPR; Induced pluripotent stem cell; Genetics; RNA polymerase II; Promoter; Gene expression","score_opus":0.009286497385206037,"score_gpt":0.22586288487946654,"score_spread":0.2165763874942605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108031137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9735451,0.008777144,0.015704695,0.00044307605,0.0006140336,0.00061702705,0.00020224025,0.00009418157,0.0000025103907],"genre_scores_gemma":[0.99637955,0.002330316,0.00062429527,0.00007010979,0.00037816862,0.000086529915,0.000011201673,0.0001029974,0.000016801529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979758,0.00008850877,0.00039861238,0.00085111376,0.00023903811,0.0004468805],"domain_scores_gemma":[0.998824,0.000015312346,0.00019711666,0.00061801606,0.00013344591,0.00021210895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021714189,0.00049924303,0.0003013432,0.000057222984,0.00048502476,0.00015909465,0.00030329186,0.0004704144,0.000007653273],"category_scores_gemma":[0.00008056147,0.0004464907,0.00013775582,0.00011799062,0.00009695352,0.000008410611,0.00048259966,0.00032391123,0.000002682853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033800337,0.000028028639,0.0023663498,0.00014853248,0.00012459209,0.0000022205131,0.000021934946,0.00007170155,0.9968318,0.000050383012,0.00030440706,0.000016289498],"study_design_scores_gemma":[0.0003305749,0.00010647097,0.02542477,0.00006499658,0.00010668702,4.1011614e-8,0.000011655323,0.00038407466,0.9590768,0.000004036413,0.0139373345,0.00055251236],"about_ca_topic_score_codex":0.00003183177,"about_ca_topic_score_gemma":0.000010711836,"teacher_disagreement_score":0.037754916,"about_ca_system_score_codex":0.000093879135,"about_ca_system_score_gemma":0.00011234266,"threshold_uncertainty_score":0.99979866},"labels":[],"label_agreement":null},{"id":"W3108386878","doi":"10.17504/protocols.io.x37fqrn","title":"Tranfection of sgRNA using SpCas9 containing plasmids to generate cell lines with Cas9 v1","year":2019,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Cas9; Electroporation; Ribonucleoprotein; Subgenomic mRNA; Plasmid; CRISPR; Nuclease; Genome editing; Transfection; Guide RNA; Biology; Cell biology; Chemistry; Molecular biology; RNA; Cell culture; Computational biology; Genetics; Gene","score_opus":0.013336830707824052,"score_gpt":0.29296284122211425,"score_spread":0.2796260105142902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108386878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7838658,0.00040571406,0.2137834,0.000013844726,0.0003730441,0.00029380384,0.000023361026,0.000013865407,0.001227139],"genre_scores_gemma":[0.984773,0.00008397701,0.013897469,0.00005279471,0.0003257309,0.000013061764,0.00009453884,0.00005107937,0.0007083542],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888927,0.000022296024,0.00027127803,0.000469752,0.00012115639,0.0002262607],"domain_scores_gemma":[0.9992643,0.000007332688,0.00009999457,0.00040849496,0.0001370373,0.00008281643],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000111849775,0.000279752,0.00030749332,0.000088950546,0.000027840413,0.000025707244,0.00014197908,0.0002908865,0.000018096163],"category_scores_gemma":[0.000010159326,0.00025133137,0.000107669046,0.00006503103,0.000020361718,0.0000014173619,0.00019732423,0.0001656524,0.0000033374913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007893309,0.000017879605,0.00074311224,0.00015102194,0.00005853451,0.0000017548637,0.000054529686,0.3984192,0.6001538,0.000002836833,0.00006127521,0.0002571459],"study_design_scores_gemma":[0.00043890314,0.0004685983,0.0002704591,0.00009479444,0.00007850283,0.000019650415,0.00008184883,0.0115617225,0.9852511,0.0000029027458,0.0013672565,0.0003642215],"about_ca_topic_score_codex":0.00023291569,"about_ca_topic_score_gemma":0.00012460862,"teacher_disagreement_score":0.38685748,"about_ca_system_score_codex":0.000018787956,"about_ca_system_score_gemma":0.00013041805,"threshold_uncertainty_score":0.9999939},"labels":[],"label_agreement":null},{"id":"W3109225371","doi":"10.1063/5.0029846","title":"Is microfluidics the “assembly line” for CRISPR-Cas9 gene-editing?","year":2020,"lang":"en","type":"article","venue":"Biomicrofluidics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Genome editing; Microfluidics; Cas9; Assembly line; Line (geometry); Nanotechnology; Computational biology; Computer science; Gene; Biology; Genetics; Engineering; Materials science","score_opus":0.025436904086458538,"score_gpt":0.31285860486090394,"score_spread":0.2874217007744454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109225371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5520209,0.03949491,0.3940031,0.01183858,0.0009984068,0.00090604345,0.00047969935,0.000090062036,0.00016828904],"genre_scores_gemma":[0.9746979,0.004534394,0.0037365214,0.012412268,0.0037394546,0.000080040685,0.0002894382,0.00012939551,0.0003806163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985856,0.000025556908,0.00033150477,0.00049975386,0.00013371785,0.00042387127],"domain_scores_gemma":[0.99915355,0.00002787361,0.0000766216,0.0004327168,0.00013640277,0.00017284701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019391239,0.00027417342,0.00019690076,0.000027085525,0.00019045966,0.00006643763,0.0004605025,0.00022372739,0.0000132898695],"category_scores_gemma":[0.00015212085,0.00023081519,0.00024407625,0.00014704409,0.000086144384,0.0000035334667,0.00018695313,0.00011449838,0.000033469667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044732285,0.00001583092,0.00016127928,0.00003634187,0.000059651768,0.0000013474864,0.00015721993,0.0000073980773,0.7989358,0.000025756906,0.19907066,0.001483985],"study_design_scores_gemma":[0.00039360079,0.00014545569,0.00005134077,0.000004098397,0.000027003929,0.00000982042,0.00007532344,0.0002464873,0.5760025,0.000009020886,0.42286944,0.00016593802],"about_ca_topic_score_codex":0.000008052819,"about_ca_topic_score_gemma":9.880085e-7,"teacher_disagreement_score":0.42267695,"about_ca_system_score_codex":0.000013355231,"about_ca_system_score_gemma":0.00008761316,"threshold_uncertainty_score":0.94123703},"labels":[],"label_agreement":null},{"id":"W3109899915","doi":"10.21926/obm.genet.2004120","title":"Genetic Stability, Inheritance Patterns and Expression Stability in Biotech Crops","year":2020,"lang":"en","type":"article","venue":"OBM Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BASF (Canada)","funders":"","keywords":"Canola; Brassica; Biology; Biotechnology; Gene; Mendelian inheritance; Genetics; Crop; Inheritance (genetic algorithm); Genetically modified crops; Transgene; Agronomy","score_opus":0.017840177373599882,"score_gpt":0.27316940078932234,"score_spread":0.25532922341572245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109899915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786785,0.003261221,0.01736708,0.00022409497,0.000077489865,0.0002522765,0.000037377176,0.000020162599,0.0000817967],"genre_scores_gemma":[0.99336296,0.0011441908,0.00506657,0.00020260159,0.00014908762,0.000017802377,0.000017362894,0.000032729404,0.000006682247],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864507,0.000059073605,0.00029483237,0.0005628978,0.00014037314,0.0002977738],"domain_scores_gemma":[0.99932176,0.000012693016,0.000041953423,0.00040387202,0.000042432865,0.0001773095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106031766,0.00020789933,0.00018212579,0.00002350083,0.000038714817,0.000030146635,0.0001907469,0.00018298614,0.000044282046],"category_scores_gemma":[0.00007681374,0.0002192179,0.00004543103,0.00011354989,0.000070810245,0.0000027243889,0.00027214678,0.00014647856,0.00000327107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027919066,0.00003237291,0.23199649,0.00008997755,0.000005133539,0.0000039981683,0.00026606407,0.0003316544,0.76431346,0.0000010877469,0.00004376294,0.002888064],"study_design_scores_gemma":[0.00043327347,0.00021009998,0.20956932,0.00001766268,0.000006762251,0.000004673773,0.00017583302,0.0010373803,0.7857301,0.000022477996,0.0025343506,0.00025803494],"about_ca_topic_score_codex":0.000019663723,"about_ca_topic_score_gemma":0.000151812,"teacher_disagreement_score":0.022427168,"about_ca_system_score_codex":0.000013913677,"about_ca_system_score_gemma":0.00003630504,"threshold_uncertainty_score":0.8939446},"labels":[],"label_agreement":null},{"id":"W3110511969","doi":"10.1128/aem.02181-20","title":"Creation of Universal Primers Targeting Nonconserved, Horizontally Mobile Genes: Lessons and Considerations","year":2020,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Computational biology; Biology; Genetics; Gene; Mobile genetic elements; Genome","score_opus":0.0047152002601744195,"score_gpt":0.2156915746571245,"score_spread":0.21097637439695008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110511969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99653226,0.001492795,0.0014901139,0.0001254532,0.000017142009,0.00013548465,0.00006352733,0.0000050913677,0.00013811106],"genre_scores_gemma":[0.9972667,0.0006124098,0.0016532642,0.00013531375,0.000034375258,0.000007934556,0.00027051204,0.000009024254,0.000010434913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956286,0.000010007849,0.00011041464,0.00020725279,0.000012985178,0.00009647442],"domain_scores_gemma":[0.9998476,0.000011387676,0.00003407498,0.00005569011,0.0000021624296,0.000049115177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000026884818,0.00008974808,0.00010473738,0.0000109414505,0.000047994094,0.0000040061223,0.000027091755,0.000080977596,0.000020185893],"category_scores_gemma":[0.0000032499663,0.000094586256,0.000019086116,0.000012261417,0.00015298609,0.0000016929658,0.00007968246,0.000037918533,0.0000013647184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018019662,0.000012884289,0.0010524545,0.0000108439335,0.000027961398,6.0488844e-7,0.0001457998,0.00020269037,0.99740404,0.000083052444,0.000087083055,0.00095458905],"study_design_scores_gemma":[0.0005616459,0.0002532274,0.0012454619,0.0000021434098,0.00002633311,0.000024266143,0.0012583886,0.000057206857,0.98955137,0.0000127044905,0.006863728,0.00014350621],"about_ca_topic_score_codex":0.000008077934,"about_ca_topic_score_gemma":0.0000036628621,"teacher_disagreement_score":0.007852629,"about_ca_system_score_codex":0.000004665208,"about_ca_system_score_gemma":0.000009348426,"threshold_uncertainty_score":0.38571155},"labels":[],"label_agreement":null},{"id":"W3110545125","doi":"10.1182/blood.2019004108","title":"CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network; Princess Margaret Cancer Centre","funders":"Canadian Institutes of Health Research; Princess Margaret Cancer Foundation","keywords":"CRISPR; Cancer research; Biology; Leukemia; Myeloid leukemia; Immunology; Medicine; Gene; Genetics","score_opus":0.018115423116292533,"score_gpt":0.2713269304883873,"score_spread":0.25321150737209475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110545125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98919404,0.0019925048,0.0067305206,0.00044693457,0.00013543598,0.00029293797,0.000034945173,0.000038783743,0.0011339],"genre_scores_gemma":[0.99560946,0.0005342582,0.0018576123,0.00096678146,0.00042554963,0.000015443213,0.000029715999,0.000035877583,0.00052528945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991011,0.00002167312,0.00013300266,0.00037380733,0.00012896955,0.00024143935],"domain_scores_gemma":[0.99947864,0.000010420512,0.00003221074,0.00025540683,0.00005438588,0.00016892469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000056020737,0.00018429713,0.00015127628,0.00002494635,0.00005534976,0.000046492423,0.0001767916,0.00009348088,0.000028676557],"category_scores_gemma":[0.000009149902,0.00017900187,0.000095659365,0.00008996565,0.000024877432,0.0000029010787,0.000114657516,0.00006664186,0.000057920453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008370122,0.000053101256,0.00031367794,0.000015706999,0.00006556153,0.000009763579,0.0003171045,0.0004296414,0.99542916,0.0000023750317,0.0028104503,0.00046972992],"study_design_scores_gemma":[0.0016692595,0.00021678355,0.000487854,0.0000054186658,0.000027042159,0.000004430882,0.00022335218,0.000020729092,0.9856844,0.000005071238,0.011421367,0.00023428086],"about_ca_topic_score_codex":0.0000412186,"about_ca_topic_score_gemma":0.000016710072,"teacher_disagreement_score":0.009744775,"about_ca_system_score_codex":0.0000023317534,"about_ca_system_score_gemma":0.00002198196,"threshold_uncertainty_score":0.72994846},"labels":[],"label_agreement":null},{"id":"W3111448780","doi":"10.1007/s00285-021-01631-0","title":"Indirect identification of horizontal gene transfer","year":2021,"lang":"en","type":"preprint","venue":"Journal of Mathematical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Stockholms Universitet; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft","keywords":"Combinatorics; Vertex (graph theory); Converse; Horizontal gene transfer; Gene duplication; Graph; Mathematics; Multipartite; Computer science; Biology; Theoretical computer science; Discrete mathematics; Gene; Genetics; Phylogenetic tree; Physics","score_opus":0.012875823068470404,"score_gpt":0.32321921105791485,"score_spread":0.31034338798944444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111448780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75403607,0.0024087715,0.24293007,0.000058862413,0.0003720976,0.00007878694,0.000023817158,0.00000226441,0.000089273424],"genre_scores_gemma":[0.99301887,0.00064377,0.005887794,0.000014369807,0.0003190661,0.0000044461217,0.00006881386,0.000018006354,0.000024888554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857724,0.0000836396,0.0008837443,0.00019288952,0.00011916673,0.0001433028],"domain_scores_gemma":[0.99911886,0.000034215853,0.00026049232,0.0002884785,0.00022866925,0.0000692532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004921548,0.00016561788,0.0005109857,0.000084957675,0.000012690809,0.000013706021,0.0002734225,0.00043597454,0.00004509528],"category_scores_gemma":[0.00023851768,0.00013960394,0.0003466634,0.000044124172,0.00007590323,0.0000016559939,0.00014691187,0.00028810577,0.0000016060146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034656507,0.000114501396,0.00011318745,0.00021851592,0.0002501063,0.000006357983,0.00010523504,0.00014866091,0.99754167,0.00015687216,0.000050900257,0.0012593392],"study_design_scores_gemma":[0.00026193573,0.00029552952,0.00043510782,0.00008744171,0.00011851434,0.00019112515,0.00006815896,0.000077025725,0.99644804,0.0016367481,0.00023846672,0.00014188958],"about_ca_topic_score_codex":9.951018e-7,"about_ca_topic_score_gemma":0.0000015471356,"teacher_disagreement_score":0.23898278,"about_ca_system_score_codex":0.000012703448,"about_ca_system_score_gemma":0.00012376097,"threshold_uncertainty_score":0.5692884},"labels":[],"label_agreement":null},{"id":"W3111841342","doi":"10.1016/j.jmb.2020.166759","title":"Anti-CRISPR AcrIE2 Binds the Type I-E CRISPR-Cas Complex But Does Not Block DNA Binding","year":2020,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; DNA; Nuclease; Binding site; Cas9; Mutagenesis; Biology; Genetics; Computational biology; Chemistry; Gene; Mutation","score_opus":0.01828161858712773,"score_gpt":0.3326203089580139,"score_spread":0.3143386903708862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111841342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705641,0.0011891449,0.02264332,0.0046818694,0.00061986124,0.0001237282,0.000030975723,0.000011388008,0.00013556586],"genre_scores_gemma":[0.9951788,0.0004171178,0.0013161348,0.0022709975,0.00069570827,0.0000019506786,0.000025736239,0.000036954876,0.000056593955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998538,0.00014021127,0.00049833505,0.00029108668,0.00016569409,0.00036662674],"domain_scores_gemma":[0.99900657,0.000031156058,0.00025200666,0.00030321936,0.00022163264,0.00018539665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029258346,0.00024716384,0.00036600133,0.000073325755,0.000100444566,0.00003627699,0.00054528494,0.00022465695,0.000036979658],"category_scores_gemma":[0.00031734462,0.00015779235,0.00025426425,0.00017358655,0.00013258324,0.000004301696,0.00021138406,0.00032119435,0.000015449934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001083884,0.000026269005,0.0010416249,0.000017056525,0.00019943394,0.000057068948,0.00008542074,0.00036134175,0.995999,0.000068590554,0.0015041868,0.00053163286],"study_design_scores_gemma":[0.00060150144,0.00078389404,0.0010511448,0.000010618215,0.00008050501,0.00025666278,0.00018222758,0.00012782078,0.95647496,0.00003591706,0.040169466,0.00022527586],"about_ca_topic_score_codex":0.000005740331,"about_ca_topic_score_gemma":0.0000030355823,"teacher_disagreement_score":0.03952402,"about_ca_system_score_codex":0.000013560971,"about_ca_system_score_gemma":0.00009045039,"threshold_uncertainty_score":0.64345855},"labels":[],"label_agreement":null},{"id":"W3111845758","doi":"10.1016/j.stemcr.2020.11.005","title":"TINC— A Method to Dissect Regulatory Complexes at Single-Locus Resolution— Reveals an Extensive Protein Complex at the Nanog Promoter","year":2020,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"Australian Research Council; Medical Research Council; National Health and Medical Research Council; State Government of Victoria; Australian Government; Stem Cells Australia; Howard Hughes Medical Institute","keywords":"Biology; Homeobox protein NANOG; Chromatin; Epigenome; Nanog Homeobox Protein; Embryonic stem cell; Gene; Promoter; Transcription factor; Computational biology; Genetics; Psychological repression; Regulation of gene expression; Epigenetics; Transcriptional regulation; Cell biology; Gene expression; DNA methylation; Induced pluripotent stem cell","score_opus":0.02509391573438511,"score_gpt":0.29394162476038965,"score_spread":0.2688477090260045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111845758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862208,0.00075372355,0.009891738,0.0005854788,0.00009240983,0.0010725007,0.000019381996,0.000046424262,0.0013175486],"genre_scores_gemma":[0.98945075,0.000002561741,0.0049782363,0.00046616755,0.00023516748,0.00007491474,0.000106787404,0.000051660772,0.0046337317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99810153,0.0001622292,0.0004361612,0.000708883,0.00024463102,0.00034654303],"domain_scores_gemma":[0.99864095,0.00001465779,0.00018091736,0.00078227127,0.00012631035,0.0002548915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036671627,0.0002461954,0.00025190573,0.000022706163,0.00020889506,0.00003266241,0.00016082652,0.00011421625,0.000053250576],"category_scores_gemma":[0.00004109935,0.00019530502,0.00012230691,0.000112110465,0.000056041285,0.0000037883658,0.00039172426,0.00008274941,0.000014555285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007796774,0.0000288363,0.00022741772,0.00006274887,0.00002384076,0.00010391496,0.00035360688,0.00076142664,0.99188286,0.000004065972,0.0054846676,0.0009886513],"study_design_scores_gemma":[0.00013744403,0.00041712067,0.0015937181,0.000023382072,0.000024225863,0.00032907823,0.00009728344,0.00011881251,0.92842096,0.000015622278,0.06854703,0.00027530623],"about_ca_topic_score_codex":0.000012624744,"about_ca_topic_score_gemma":0.00003398601,"teacher_disagreement_score":0.063461885,"about_ca_system_score_codex":0.000054365184,"about_ca_system_score_gemma":0.00004180993,"threshold_uncertainty_score":0.79643077},"labels":[],"label_agreement":null},{"id":"W3112176049","doi":"10.3389/fmolb.2020.595474","title":"Homology-Directed Repair in Zebrafish: Witchcraft and Wizardry?","year":2020,"lang":"en","type":"review","venue":"Frontiers in Molecular Biosciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Heart and Stroke Foundation of Canada","keywords":"Zebrafish; CRISPR; Computational biology; Mutagenesis; Biology; Genome editing; Gene; Palindrome; Genetics; Zinc finger nuclease; Mutant; Homology (biology); Homology modeling; Model organism; Genome; Genetic screen","score_opus":0.00821499841811637,"score_gpt":0.29563016760206395,"score_spread":0.2874151691839476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112176049","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005693599,0.993365,0.004719721,0.000057013447,0.00061382825,0.00046586033,0.000029227991,0.000045602133,0.00013437841],"genre_scores_gemma":[0.00038880578,0.9828757,0.016328402,0.00011031867,0.00007038051,0.00006442467,0.000058026362,0.0000410108,0.000062941945],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99776405,0.00016416724,0.000467058,0.000990904,0.00017724153,0.00043658644],"domain_scores_gemma":[0.9993677,0.000011990896,0.00011016686,0.00036156835,0.00001855921,0.00013001391],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029678064,0.00040852145,0.0009203213,0.00033885814,0.000038568476,0.000029684517,0.00045601386,0.00043521638,0.0000024169851],"category_scores_gemma":[0.00021948315,0.00038392175,0.0002296861,0.00078308873,0.00027768736,0.000004770765,0.0002546312,0.00029631372,0.0000017630857],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005159287,0.000212934,0.0039999,0.007562763,0.0004194732,0.0012231366,0.00030741078,0.00013418111,0.0094826,0.00007121859,0.0177653,0.9587695],"study_design_scores_gemma":[0.00024739484,0.0001630517,0.00012137404,0.0008260791,0.00008090841,0.00006308428,0.00007335686,0.00027866836,0.00074105035,0.000046409983,0.9967711,0.00058752997],"about_ca_topic_score_codex":0.000023558865,"about_ca_topic_score_gemma":0.00004397185,"teacher_disagreement_score":0.9790058,"about_ca_system_score_codex":0.000037074726,"about_ca_system_score_gemma":0.00022411253,"threshold_uncertainty_score":0.99986124},"labels":[],"label_agreement":null},{"id":"W3112267878","doi":"10.2174/1566523220666201214115024","title":"CRISPR/Cas9 Technology as a Modern Genetic Manipulation Tool for Recapitulating of Neurodegenerative Disorders in Large Animal Models","year":2020,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"CRISPR; Cas9; Genome editing; Neuroscience; Biology; Disease; Computational biology; Animal model; Transgene; Gene knockin; Bioinformatics; Gene; Medicine; Genetics; Pathology","score_opus":0.04132951322094621,"score_gpt":0.37839010698330894,"score_spread":0.33706059376236275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112267878","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011837593,0.8705457,0.115703784,0.000018019999,0.000211375,0.0015422441,0.00010751601,0.000023047874,0.000010723912],"genre_scores_gemma":[0.046469986,0.9502483,0.0020264906,0.0000108559825,0.00024974137,0.00043896085,0.00043527846,0.00011171915,0.0000086602],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979208,0.00008437333,0.00071600894,0.00074802095,0.00013724848,0.0003935376],"domain_scores_gemma":[0.9991326,0.000021690028,0.00028248556,0.0004355597,0.00007287832,0.00005480664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012794072,0.00048908324,0.00091573526,0.00022479462,0.000051466624,0.000016311827,0.00033681624,0.0003704823,0.000004900265],"category_scores_gemma":[0.000042601554,0.00048376614,0.00037870757,0.00028826846,0.000036228565,0.000005530067,0.00012553022,0.0002400082,0.0000017196271],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006953427,0.00010831606,0.00003332025,0.001409021,0.00010332168,9.237161e-7,0.00011847757,0.0050398977,0.010782783,0.00012641375,0.000025738147,0.98218226],"study_design_scores_gemma":[0.0031827046,0.0020047333,0.00005317912,0.0017965501,0.00033232625,0.000036447767,0.000045724453,0.0671168,0.022330314,0.0027013465,0.89848447,0.0019154111],"about_ca_topic_score_codex":0.0000024283481,"about_ca_topic_score_gemma":0.000012840493,"teacher_disagreement_score":0.98026687,"about_ca_system_score_codex":0.00003031958,"about_ca_system_score_gemma":0.00016766597,"threshold_uncertainty_score":0.9997614},"labels":[],"label_agreement":null},{"id":"W3112395311","doi":"10.1093/neuonc/noaa215.892","title":"TAMI-03. IDENTIFICATION OF NOVEL DRIVERS OF LUNG-TO-BRAIN METASTASIS THROUGH IN VIVO FUNCTIONAL GENOMICS","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Brain metastasis; Metastasis; Primary tumor; Lung cancer; In vivo; Cancer research; Functional genomics; Cancer; Medicine; Cas9; Biology; Genome; Computational biology; Gene; Genomics; Oncology; Internal medicine; Genetics","score_opus":0.02125884097446389,"score_gpt":0.3050911775633286,"score_spread":0.2838323365888647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112395311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.902602,0.000118140444,0.094917275,0.0014236785,0.00026418013,0.00021887622,0.00008627494,0.0000069620323,0.0003626127],"genre_scores_gemma":[0.9963106,0.00006914665,0.0025208085,0.0009227376,0.00009695801,0.000014199861,0.00003338381,0.000016332324,0.000015868565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991111,0.000038728616,0.00034435635,0.00027955463,0.000087991866,0.00013823136],"domain_scores_gemma":[0.9995428,0.00004413623,0.00011242909,0.00017281175,0.00007172091,0.000056120294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011228099,0.00010068172,0.0002016905,0.0000489372,0.00001394553,0.000003016022,0.00014301036,0.000114387505,0.000027997681],"category_scores_gemma":[0.00022184697,0.000115039154,0.00007107638,0.00016997982,0.000050121747,0.0000037612583,0.00009815467,0.00008037642,0.0000029841726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009656726,0.00007721278,0.00055220514,0.000031673528,0.000031565247,0.0000018032426,0.00035006445,0.019591032,0.97589445,0.00012306085,0.0026114117,0.0006389261],"study_design_scores_gemma":[0.0007440965,0.00048372603,0.0013929798,0.000002353131,0.000024908739,0.0000067027822,0.0001394672,0.0016785874,0.93608046,0.000008223813,0.05934633,0.00009215597],"about_ca_topic_score_codex":0.000011369742,"about_ca_topic_score_gemma":0.00002201036,"teacher_disagreement_score":0.09370857,"about_ca_system_score_codex":0.000026631324,"about_ca_system_score_gemma":0.00009956762,"threshold_uncertainty_score":0.46911606},"labels":[],"label_agreement":null},{"id":"W3112756000","doi":"10.1111/febs.15621","title":"CRISPR: development of a technology and its applications","year":2020,"lang":"en","type":"editorial","venue":"FEBS Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"CRISPR; Biology; Palindrome; Genome editing; Computational biology; Genetics; Gene","score_opus":0.005539778900512906,"score_gpt":0.2917781842164314,"score_spread":0.28623840531591854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112756000","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0149686895,0.108170696,0.2748036,0.0008694636,0.59866744,0.0010179295,0.00026394604,0.00007271811,0.0011655068],"genre_scores_gemma":[0.049792975,0.005877913,0.02505173,0.00003483871,0.9178557,0.00010606012,0.00031905246,0.00010931841,0.0008524586],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992194,0.000008229589,0.00028003348,0.00019421775,0.00015764084,0.00014045644],"domain_scores_gemma":[0.9994761,0.00001171859,0.00013555386,0.00011780991,0.0001728838,0.00008596533],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009421779,0.0001416856,0.00018655462,0.000119939825,0.00007072245,0.000016017086,0.00019924968,0.00044710183,0.0000079331385],"category_scores_gemma":[0.00017646604,0.00014021268,0.000047798945,0.00009963915,0.000023671182,9.940102e-7,0.00013578392,0.0003821377,0.0000041321587],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029904064,0.000029739114,0.000024648603,0.0002048589,0.00020347907,0.000005320553,0.00008994116,0.00002175643,0.21021377,0.000026706044,0.76995844,0.019191425],"study_design_scores_gemma":[0.00019898999,0.000072531984,0.000012554914,0.000032641266,0.00002488297,0.000028003156,0.000026294816,0.0000052156347,0.090874664,0.00002823501,0.90856993,0.0001260774],"about_ca_topic_score_codex":1.3264263e-7,"about_ca_topic_score_gemma":0.000001595399,"teacher_disagreement_score":0.3191882,"about_ca_system_score_codex":0.000011040367,"about_ca_system_score_gemma":0.00029614862,"threshold_uncertainty_score":0.5717707},"labels":[],"label_agreement":null},{"id":"W3112796825","doi":"10.1098/rsob.200188","title":"The interesting relationship between APOBEC3 deoxycytidine deaminases and cancer: a long road ahead","year":2020,"lang":"en","type":"article","venue":"Open Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"APOBEC; Biology; Cytidine deaminase; Somatic cell; Genetics; Cytidine; Genome instability; Mutation; Cancer research; Somatic hypermutation; APOBEC3G; Context (archaeology); Cancer; Deamination; Cytosine; Enzyme; DNA; DNA damage; Gene; Biochemistry; Genome; Antibody; B cell","score_opus":0.055621075869121316,"score_gpt":0.3957623141141069,"score_spread":0.3401412382449856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112796825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98805046,0.0051149298,0.004044493,0.0020035096,0.000072218005,0.0002004419,0.000019547073,0.000010016535,0.0004844114],"genre_scores_gemma":[0.9985404,0.00032091417,0.0003998703,0.00020509932,0.00028473983,0.00002965675,0.000057659126,0.00001241965,0.00014925738],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99933505,0.000056200395,0.00015133459,0.0002535055,0.000023843144,0.00018005328],"domain_scores_gemma":[0.99961543,0.00008986592,0.000044114317,0.00014682255,0.000023678822,0.000080070975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014140109,0.00010148716,0.00011780346,0.000009326996,0.00016210905,0.000048181904,0.0002754456,0.00008856827,0.0000060867937],"category_scores_gemma":[0.00036788074,0.00007677828,0.000024780024,0.000059419588,0.00007664272,0.0000028901786,0.0003975209,0.00009261487,0.0000040221407],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046446305,0.000004584534,0.8859698,0.00001601825,0.000046672714,0.0000015736542,0.00008172323,0.000043907494,0.043629505,0.0002303829,0.00063547544,0.06929388],"study_design_scores_gemma":[0.00083342235,0.00059291703,0.8396261,0.00003837936,0.000053623193,0.000019103023,0.00018565521,0.0003563465,0.066995874,0.00021454428,0.09070521,0.00037882745],"about_ca_topic_score_codex":0.00017106577,"about_ca_topic_score_gemma":0.00026776356,"teacher_disagreement_score":0.09006973,"about_ca_system_score_codex":0.000005695346,"about_ca_system_score_gemma":0.00003167229,"threshold_uncertainty_score":0.31309274},"labels":[],"label_agreement":null},{"id":"W3113064477","doi":"10.1093/synbio/ysaa019","title":"Modular cell-free expression plasmids to accelerate biological design in cells","year":2020,"lang":"en","type":"article","venue":"Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biological and Environmental Research; Office of Science; U.S. Department of Energy; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Joint Genome Institute; Suncor Energy Incorporated","keywords":"Synthetic biology; Metabolic engineering; Computational biology; Plasmid; Modular design; Biochemical engineering; Biology; Computer science; Expression vector; Biotechnology; DNA; Gene; Genetics; Engineering; Recombinant DNA","score_opus":0.025265196110474394,"score_gpt":0.2949021593929583,"score_spread":0.2696369632824839,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113064477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8072097,0.00058094296,0.19024113,0.00088081456,0.00024153887,0.0003563778,0.000027230193,0.00003453471,0.00042776388],"genre_scores_gemma":[0.98713595,0.00016120065,0.011579056,0.00083600706,0.00015155607,0.000048785718,0.000023550261,0.000023379132,0.00004052115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985941,0.0001455569,0.0002438071,0.00057706016,0.000052716376,0.00038676217],"domain_scores_gemma":[0.9993404,0.000035340447,0.00003335231,0.00038259628,0.000023061257,0.00018523657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016954524,0.00021047336,0.00022878736,0.000050559378,0.000033632128,0.000011232796,0.00044040746,0.00030720295,0.000070513],"category_scores_gemma":[0.0001554933,0.00017930068,0.000066533394,0.00012525835,0.000059368107,0.0000015739852,0.00033950186,0.00013365639,0.00006240881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001171716,0.00003515292,0.0003103763,0.000011144342,0.000005826244,0.000005470697,0.000071809474,0.0064224126,0.99124074,0.000019544621,0.0010627736,0.00069760316],"study_design_scores_gemma":[0.0004585878,0.0006335663,0.0003014146,0.000010239153,0.0000036879574,0.0000034377963,0.000040976578,0.0008299198,0.9816303,0.000110503715,0.015735513,0.0002418011],"about_ca_topic_score_codex":0.000005647438,"about_ca_topic_score_gemma":0.0000023989708,"teacher_disagreement_score":0.17992628,"about_ca_system_score_codex":0.000009801991,"about_ca_system_score_gemma":0.000028237184,"threshold_uncertainty_score":0.73116696},"labels":[],"label_agreement":null},{"id":"W3113698616","doi":"10.1089/crispr.2020.0049","title":"Heritable Human Genome Editing: The Public Engagement Imperative","year":2020,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Obligation; Genome editing; Warrant; Bioethics; Commission; Political science; Public engagement; Public relations; Genome; Law; Biology; Genetics; Business","score_opus":0.029694351361122615,"score_gpt":0.3177105939838223,"score_spread":0.28801624262269965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113698616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8693893,0.0081533035,0.064867586,0.052378446,0.0007629016,0.0004030731,0.000014673665,0.00003665224,0.003994084],"genre_scores_gemma":[0.9949412,0.00021637857,0.00017180326,0.001646035,0.0027748833,0.000008904228,0.0000086981745,0.000020048474,0.00021209546],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99911445,0.0001260997,0.0001871355,0.00014358123,0.00015358209,0.0002751425],"domain_scores_gemma":[0.9995094,0.000012389301,0.0000643746,0.00020953348,0.000079345285,0.00012494973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053501484,0.00012392504,0.000090658155,0.000011969283,0.0006771496,0.00017015413,0.00042814997,0.000041603675,0.00016507259],"category_scores_gemma":[0.00010246654,0.00007118639,0.000093806295,0.00007434356,0.00006228328,0.0000050444914,0.00016925187,0.00037970758,0.000016000804],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010635872,0.000017377264,0.000122085,0.000006910556,0.0001154774,0.0000078981,0.0012620236,0.0007103328,0.97796535,0.0003355734,0.018816093,0.00063026126],"study_design_scores_gemma":[0.0006631952,0.00046355632,0.0019610527,0.000007865635,0.000058762103,0.00025675196,0.00491612,0.0003630632,0.18850845,0.00019474007,0.80232227,0.00028420123],"about_ca_topic_score_codex":0.0000017136343,"about_ca_topic_score_gemma":0.000004002895,"teacher_disagreement_score":0.7894569,"about_ca_system_score_codex":0.000011639233,"about_ca_system_score_gemma":0.000040669158,"threshold_uncertainty_score":0.5208156},"labels":[],"label_agreement":null},{"id":"W3115713778","doi":"10.1093/neuonc/noaa306","title":"Modeling human brain tumors in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets","year":2020,"lang":"en","type":"review","venue":"Neuro-Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Zebrafish; Biology; Danio; Model organism; Caenorhabditis elegans; Computational biology; Drosophila melanogaster; Genome; RNA interference; Neuroscience; Genetics; RNA; Gene","score_opus":0.03541518766050802,"score_gpt":0.3599964333821772,"score_spread":0.3245812457216692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3115713778","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0044150646,0.9875484,0.006437984,0.00017123317,0.00022837348,0.0009675331,0.00010208294,0.000015716245,0.0001135982],"genre_scores_gemma":[0.035452172,0.9589878,0.002569467,0.0011634137,0.0006469195,0.0002926111,0.0006309541,0.00021269314,0.000043986773],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99814135,0.000104287654,0.0006494624,0.0006828668,0.00010704374,0.000315009],"domain_scores_gemma":[0.99926096,0.00007279505,0.00013700855,0.0003544651,0.000032952135,0.00014182179],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015870936,0.00036934696,0.0012121168,0.00012523237,0.00003103917,0.000011724925,0.00031931465,0.00041532685,0.0000109874345],"category_scores_gemma":[0.00014519556,0.00035250405,0.00015238897,0.00016476608,0.00004369915,0.000002408918,0.00036307183,0.00036487795,0.0000024258984],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057970203,0.00023016556,0.00001977365,0.0024057874,0.00018294266,0.000054950553,0.0003676112,0.0026856249,0.45094636,0.000071791605,0.00026873048,0.5427083],"study_design_scores_gemma":[0.00051570946,0.0005989404,0.0000069265957,0.00041005033,0.00009079033,0.000031125965,0.000020733192,0.00078852486,0.004352255,0.000020221267,0.99283683,0.00032789164],"about_ca_topic_score_codex":0.00003620934,"about_ca_topic_score_gemma":0.00019360971,"teacher_disagreement_score":0.9925681,"about_ca_system_score_codex":0.00004774167,"about_ca_system_score_gemma":0.00026702468,"threshold_uncertainty_score":0.9998927},"labels":[],"label_agreement":null},{"id":"W3117195455","doi":"10.1038/s41596-020-00423-y","title":"An unbiased method for evaluating the genome-wide specificity of base editors in rice","year":2020,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Genome; Computational biology; Base (topology); Transformation (genetics); Biology; Pipeline (software); Reference genome; Computer science; Genetics; Gene; Mathematics","score_opus":0.031153656603107868,"score_gpt":0.4252165852204996,"score_spread":0.39406292861739173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3117195455","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24980845,0.00052294094,0.618209,0.0020134805,0.00040436676,0.1285136,0.00014076888,0.000041736184,0.0003456437],"genre_scores_gemma":[0.86647207,0.0000024892618,0.09241843,0.0010281426,0.0029050023,0.03703069,0.00008002631,0.00004223833,0.000020939495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914575,0.000094451585,0.00020366142,0.00026725134,0.0001347708,0.00015410445],"domain_scores_gemma":[0.99943626,0.00007986625,0.00006998848,0.0002569027,0.000099677156,0.000057325757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062834617,0.00010981137,0.0001355816,0.000019673585,0.000031710955,0.000012916981,0.0002501948,0.00019649566,0.000006729006],"category_scores_gemma":[0.00065469166,0.000084947416,0.00006807035,0.00013482217,0.000016609127,0.0000024838805,0.000040902214,0.00022312516,3.9682607e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025262072,0.00003608677,0.00073672546,0.00012131751,0.00001224819,4.638741e-7,0.00012108399,0.005437509,0.9912405,0.000012095604,0.0007073618,0.0013219977],"study_design_scores_gemma":[0.0009578992,0.0009807169,0.0048400373,0.000021806436,0.000011809259,7.7557496e-7,0.00009042271,0.011620942,0.95179105,0.000057503737,0.029473707,0.00015332234],"about_ca_topic_score_codex":0.000004653021,"about_ca_topic_score_gemma":0.00000721868,"teacher_disagreement_score":0.6166636,"about_ca_system_score_codex":0.000008271448,"about_ca_system_score_gemma":0.000056185774,"threshold_uncertainty_score":0.3464055},"labels":[],"label_agreement":null},{"id":"W3118209894","doi":"10.1021/acschembio.0c00684","title":"Combining Rational Design and Continuous Evolution on Minimalist Proteins That Target the E-box DNA Site","year":2020,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Leucine zipper; Zipper; DNA; Computational biology; bZIP domain; Enhancer; Phosphodiester bond; Biology; Transcription factor; Chemistry; Cell biology; Biochemistry; Computer science; RNA; Gene","score_opus":0.013417777289884579,"score_gpt":0.26805637564662455,"score_spread":0.25463859835673996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118209894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9015036,0.0006901471,0.09498122,0.0022641318,0.000058461617,0.00028566242,0.000019649147,0.000020684993,0.0001764393],"genre_scores_gemma":[0.9957896,0.000024717074,0.0027393103,0.000995945,0.00021181707,0.000034742214,0.00016958703,0.00001137982,0.00002292794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932027,0.000052041472,0.00011880358,0.0002815774,0.00005071403,0.00017658163],"domain_scores_gemma":[0.99969393,0.00005178635,0.00003815139,0.00012260486,0.000025604055,0.000067935776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009734378,0.0001233601,0.000120712175,0.0000093078,0.000055253553,0.000013030746,0.00011408716,0.00014924613,0.000009126206],"category_scores_gemma":[0.00016201386,0.00009292514,0.000035181205,0.00003976199,0.00011915552,0.0000017220099,0.00008973801,0.00010905869,0.0000069901716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010778587,0.000013958104,0.0010150643,0.0000057342177,0.000021553535,7.944999e-7,0.000055309374,0.00007312568,0.9970036,0.0005107335,0.0009310514,0.00026127032],"study_design_scores_gemma":[0.00044444317,0.0003516376,0.00053280115,0.000003884888,0.000009835832,0.000010150157,0.0000295865,0.00053352694,0.9889693,0.0002134255,0.008765409,0.00013595558],"about_ca_topic_score_codex":0.0000034019781,"about_ca_topic_score_gemma":4.884689e-7,"teacher_disagreement_score":0.09428597,"about_ca_system_score_codex":0.0000070062965,"about_ca_system_score_gemma":0.00002046986,"threshold_uncertainty_score":0.37893772},"labels":[],"label_agreement":null},{"id":"W3118307659","doi":"10.1080/19336934.2020.1863124","title":"<i>Drosophila melanogaster</i>: a fruitful model for oncohistones","year":2021,"lang":"en","type":"article","venue":"Fly","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Drosophila melanogaster; Drosophila (subgenus); Biology; Evolutionary biology; Genetics; Gene","score_opus":0.014363962434455283,"score_gpt":0.3080536504481803,"score_spread":0.293689688013725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118307659","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42011505,0.0039055904,0.570261,0.00071732467,0.00049195945,0.00021717265,0.00010330214,0.000034249362,0.0041543255],"genre_scores_gemma":[0.98075944,0.000076687524,0.010900019,0.00039573904,0.00030528553,0.00003737644,0.0001440329,0.000024444815,0.0073569543],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947715,0.000005788719,0.0000963759,0.00021315578,0.000052158644,0.00015536616],"domain_scores_gemma":[0.99964756,0.0000052758496,0.000015763926,0.00022191265,0.00006014058,0.000049326867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041141284,0.00008736689,0.00008630281,0.000011362042,0.00004217759,0.000011959594,0.00007410466,0.000072277944,0.000009840772],"category_scores_gemma":[0.000032676446,0.00009298615,0.00008253595,0.000029923573,0.000014147045,0.0000010845242,0.000049696962,0.000030864117,0.000006598458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021991642,0.000027952845,0.00008298507,0.000030656953,0.00002779515,0.00000374812,0.000082439656,0.0071573975,0.98438853,0.00025177933,0.0065750624,0.001349633],"study_design_scores_gemma":[0.00081299274,0.00011927493,0.0002621842,0.0000142100525,0.000034870594,0.000042347245,0.000051944036,0.033884212,0.7956511,0.0005418473,0.16829698,0.00028807909],"about_ca_topic_score_codex":0.0000012227932,"about_ca_topic_score_gemma":0.00001965762,"teacher_disagreement_score":0.5606444,"about_ca_system_score_codex":0.000005308279,"about_ca_system_score_gemma":0.00005488527,"threshold_uncertainty_score":0.3791865},"labels":[],"label_agreement":null},{"id":"W3118588688","doi":"10.3389/fphys.2020.624129","title":"Utility of Zebrafish Models of Acquired and Inherited Long QT Syndrome","year":2021,"lang":"en","type":"review","venue":"Frontiers in Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"hERG; Zebrafish; Long QT syndrome; Repolarization; Cardiac electrophysiology; Potassium channel; Sudden death; Biology; Neuroscience; QT interval; Computational biology; Medicine; Bioinformatics; Electrophysiology; Genetics; Internal medicine; Gene","score_opus":0.01856621017913297,"score_gpt":0.30166189328276805,"score_spread":0.2830956831036351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118588688","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015593444,0.9794802,0.0042363643,0.0000014204528,0.00032997545,0.00023210839,0.00006634137,0.000003872496,0.00005628752],"genre_scores_gemma":[0.04209395,0.9558011,0.0016162075,0.000006261748,0.00003416323,0.000020303973,0.00035793122,0.000029728124,0.0000403158],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99863386,0.00013663106,0.00051484565,0.0004418011,0.000060492377,0.00021235023],"domain_scores_gemma":[0.99926174,0.000015651614,0.00018592866,0.0004455091,0.000047861668,0.00004332377],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000103172904,0.00025290088,0.0014825728,0.00010769041,0.000010284489,0.000002507819,0.0002059639,0.00047056822,0.000008328123],"category_scores_gemma":[0.000038482805,0.00025103916,0.00023008267,0.0001683438,0.00017331191,0.000002481318,0.00021906245,0.0000871329,1.207786e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013805946,0.0005138258,0.00065256597,0.060167033,0.0021304884,0.00011788233,0.0002103766,0.00075616705,0.025985852,0.00008261005,0.005639918,0.9036052],"study_design_scores_gemma":[0.0053350716,0.0022577855,0.014923933,0.031061782,0.0029907364,0.0013173581,0.0007185581,0.006076708,0.02160136,0.0028177763,0.9053947,0.0055042584],"about_ca_topic_score_codex":0.000009829579,"about_ca_topic_score_gemma":0.000004791892,"teacher_disagreement_score":0.89975476,"about_ca_system_score_codex":0.0000065072395,"about_ca_system_score_gemma":0.0000990937,"threshold_uncertainty_score":0.99999416},"labels":[],"label_agreement":null},{"id":"W3120111865","doi":"10.1007/s15010-020-01554-w","title":"CRISPR-based strategies in infectious disease diagnosis and therapy","year":2021,"lang":"en","type":"review","venue":"Infection","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"William Osler Health System","funders":"Fundação para a Ciência e a Tecnologia; Centro de Investigação em Biomedicina","keywords":"CRISPR; Genome editing; Computational biology; Infectious disease (medical specialty); Cas9; Biology; Disease; Gene; Medicine; Genetics","score_opus":0.021744002514245873,"score_gpt":0.365152051545919,"score_spread":0.34340804903167316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120111865","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028685401,0.99399996,0.0024612455,0.0000056997274,0.00023150902,0.00029843336,0.000010250083,0.000019759347,0.00010460869],"genre_scores_gemma":[0.01109798,0.98810697,0.0000196085,0.00002268683,0.00018331119,0.00032602617,0.00019555773,0.000032967357,0.000014917203],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99917305,0.00010122418,0.00019935388,0.00032718066,0.00005625776,0.00014291958],"domain_scores_gemma":[0.9996124,0.000028183578,0.000055354725,0.00021273148,0.000027655553,0.00006368431],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009899363,0.00023026041,0.00035981074,0.000112688314,0.000032022566,0.00006280648,0.000037535472,0.00020919315,0.000015012431],"category_scores_gemma":[0.000058354544,0.00021908604,0.00016674794,0.0001478252,0.000023228074,0.0000033180042,0.000030273422,0.00013578228,0.0000021169851],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003837826,0.000079710844,0.00222594,0.001963688,0.000051603845,0.000010451201,0.0000054805646,0.00053018465,0.000040841423,0.000015892465,0.00013721257,0.99493515],"study_design_scores_gemma":[0.00021828231,0.00008789458,0.00076529616,0.0011901663,0.00007367467,0.000009492019,0.0000027536921,0.00001843155,0.00022885445,0.00001434784,0.99711967,0.00027113734],"about_ca_topic_score_codex":0.00007910955,"about_ca_topic_score_gemma":0.000115849085,"teacher_disagreement_score":0.99698246,"about_ca_system_score_codex":0.000020331176,"about_ca_system_score_gemma":0.00017989584,"threshold_uncertainty_score":0.8934069},"labels":[],"label_agreement":null},{"id":"W3120114060","doi":"10.1039/d0sc06113a","title":"Amplified detection of nucleic acids and proteins using an isothermal proximity CRISPR Cas12a assay","year":2021,"lang":"en","type":"article","venue":"Chemical Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Sleep Society; Brock University","funders":"Fundamental Research Funds for the Central Universities; Brock University; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; National Natural Science Foundation of China","keywords":"CRISPR; Nucleic acid; Computational biology; Loop-mediated isothermal amplification; Molecular biology; Chemistry; Gene; Biology; DNA; Biochemistry","score_opus":0.014386336744417862,"score_gpt":0.2990126319459826,"score_spread":0.28462629520156474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120114060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9512913,0.00012895702,0.048352733,0.000011957195,0.000038935796,0.00006758553,0.0000023639807,0.000006636473,0.0000994794],"genre_scores_gemma":[0.99543566,0.000007029878,0.00445631,0.000021433074,0.000055767952,0.0000032701546,0.0000023873624,0.0000062231416,0.000011946403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932486,0.000012296583,0.00009707884,0.00028557229,0.00011626536,0.000163922],"domain_scores_gemma":[0.9996066,0.000003612691,0.00002579169,0.00019015204,0.0000829366,0.00009088305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001720412,0.00006868435,0.000072585455,0.000015990903,0.00005780726,0.000021925049,0.000106397565,0.00006519846,0.000005233176],"category_scores_gemma":[0.00014325217,0.00006663726,0.000021765836,0.00015753621,0.00021241824,0.000009206533,0.000106888896,0.000053364973,2.4955864e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000067704864,0.00002705475,0.00042234221,0.000015438247,0.0000021725268,7.8586106e-7,0.00003471571,0.000036960144,0.99699545,0.0000096706435,5.995773e-7,0.002448017],"study_design_scores_gemma":[0.000110951456,0.000038915136,0.0019546081,0.0000071203353,0.0000050259378,0.000030839718,0.00003938123,0.0022674908,0.99532205,0.00002576755,0.00011032259,0.00008749862],"about_ca_topic_score_codex":0.000014274679,"about_ca_topic_score_gemma":0.0000066845737,"teacher_disagreement_score":0.04414428,"about_ca_system_score_codex":0.000012565919,"about_ca_system_score_gemma":0.00006827175,"threshold_uncertainty_score":0.27173886},"labels":[],"label_agreement":null},{"id":"W3120689037","doi":"10.1101/2020.12.30.424813","title":"<i>Drosophila</i> functional screening of <i>de novo</i> variants in autism uncovers deleterious variants and facilitates discovery of rare neurodevelopmental diseases","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Office of Research Infrastructure Programs, National Institutes of Health; Canadian Institutes of Health Research; Intellectual and Developmental Disabilities Research Center; National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Simons Foundation Autism Research Initiative","keywords":"Autism; Autism spectrum disorder; Phenotype; Missense mutation; Gene; Genetics; Biology; Neurodevelopmental disorder; Drosophila (subgenus); Psychology; Developmental psychology","score_opus":0.007820472075290739,"score_gpt":0.21606487116758402,"score_spread":0.20824439909229328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120689037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833935,0.003076581,0.011997812,0.000032471795,0.00035990297,0.00023007291,0.00088892714,0.00001847097,0.000002253841],"genre_scores_gemma":[0.99510795,0.0007390311,0.0039141853,0.00006459442,0.00006924928,0.00003655444,0.000010782766,0.000054653327,0.00000300915],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981568,0.00007696191,0.0004921922,0.0007153838,0.00022110107,0.00033759096],"domain_scores_gemma":[0.9990404,0.00003192872,0.00019806875,0.0004942644,0.000110254354,0.00012508416],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001858446,0.00036584047,0.00045719056,0.00012435409,0.00004325486,0.00006142802,0.00021000739,0.00028446675,0.00000578041],"category_scores_gemma":[0.00015747859,0.00043406792,0.00012005458,0.00018748059,0.00011496023,0.00002064734,0.0005606053,0.00023619649,2.5804331e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008365615,0.00009809963,0.05321268,0.0004680308,0.00013405608,0.00005096053,0.00001637151,0.0028389038,0.9430561,0.00001760843,0.000017591,0.000005933311],"study_design_scores_gemma":[0.0007032064,0.00006014997,0.66379446,0.00033431491,0.000056863522,3.510483e-7,0.000013881693,0.00020814837,0.33437362,0.000001343055,0.00006521502,0.0003884366],"about_ca_topic_score_codex":0.000060711198,"about_ca_topic_score_gemma":0.000006094278,"teacher_disagreement_score":0.6105818,"about_ca_system_score_codex":0.00004038063,"about_ca_system_score_gemma":0.00047433542,"threshold_uncertainty_score":0.9998111},"labels":[],"label_agreement":null},{"id":"W3121718041","doi":"","title":"Why the Shift? Taking a Closer Look at the Growing Interest in Niche Markets and Personalized Medicine","year":2015,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Pharmacogenomics; Niche; Niche market; Pharmaceutical industry; Personalized medicine; Business; Drug trial; Marketing; Clinical trial; Medicine; Pharmacology; Bioinformatics; Biology","score_opus":0.016284177328499003,"score_gpt":0.2900355280528374,"score_spread":0.27375135072433837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121718041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9478754,0.04018098,0.002932119,0.008432153,0.00013713667,0.00009770948,5.2763164e-7,0.0000040462664,0.00033993614],"genre_scores_gemma":[0.995278,0.0026840416,0.0000148524305,0.0010775217,0.0003829635,0.000005745123,0.000003650066,0.000018193577,0.00053501374],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99867773,0.000115484596,0.0001763035,0.00016755897,0.000116212585,0.0007467148],"domain_scores_gemma":[0.9996353,0.00003272593,0.00007189221,0.00016773201,0.00002855417,0.00006383683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018367457,0.00012963053,0.00011292883,0.00003331336,0.00011089779,0.000024030223,0.00021744441,0.0000652508,0.000017329894],"category_scores_gemma":[0.00017927964,0.00007265579,0.000049480754,0.000073596944,0.00011502012,0.0000071591,0.000121945704,0.000640692,0.0000013605888],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041081677,0.0002504029,0.086226344,0.00012576525,0.002336764,0.00011922255,0.014504642,0.0014788383,0.69769794,0.046126712,0.034231633,0.11279359],"study_design_scores_gemma":[0.024823891,0.0043429867,0.057776365,0.0007261724,0.000620947,0.013447803,0.061610818,0.0025273648,0.04318466,0.09855561,0.68993485,0.0024485148],"about_ca_topic_score_codex":0.00006146146,"about_ca_topic_score_gemma":0.002559204,"teacher_disagreement_score":0.65570325,"about_ca_system_score_codex":0.00012732987,"about_ca_system_score_gemma":0.00020837063,"threshold_uncertainty_score":0.29628173},"labels":[],"label_agreement":null},{"id":"W3121999100","doi":"10.1016/j.toxicon.2020.11.501","title":"Characterization of the protospacer targets of Clostridium botulinum CRISPR-Cas spacer arrays","year":2021,"lang":"en","type":"article","venue":"Toxicon","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Clostridium botulinum; CRISPR; Microbiology; Biology; Genetics; Toxin","score_opus":0.006507687518679635,"score_gpt":0.26728374164346935,"score_spread":0.2607760541247897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121999100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98336357,0.00031818417,0.014927852,0.00034621957,0.000230496,0.00024247168,0.000029655548,0.0000048982856,0.0005366491],"genre_scores_gemma":[0.9986491,0.00008860121,0.00029221032,0.000052734165,0.00012101165,0.0000145052845,0.000048444213,0.000013975975,0.00071937515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994614,0.000025608319,0.00015749902,0.00015048863,0.00009175197,0.00011321379],"domain_scores_gemma":[0.9994934,0.0000032722614,0.00008028873,0.00030582256,0.000090625785,0.000026563477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058954458,0.00008528756,0.00011135806,0.000012786935,0.000019492378,0.0000047687668,0.00007624921,0.00008710974,0.00004885892],"category_scores_gemma":[0.0000517849,0.00007002977,0.00008210049,0.00008340935,0.000032349286,0.0000018890998,0.000075067124,0.000051323914,0.0000015360404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014765731,0.000035427576,0.0018738353,0.000048296737,0.000022394608,5.545558e-7,0.00008187701,0.00007299198,0.9974477,0.000029826815,0.00013996907,0.00023231618],"study_design_scores_gemma":[0.00020591484,0.00004984725,0.009209587,0.000019860006,0.0000132490695,0.0000048092634,0.000035140016,0.000050208753,0.98281217,0.000013878148,0.0075092763,0.00007608743],"about_ca_topic_score_codex":0.0000035637631,"about_ca_topic_score_gemma":0.0000072802272,"teacher_disagreement_score":0.015285568,"about_ca_system_score_codex":0.0000046902614,"about_ca_system_score_gemma":0.00005543073,"threshold_uncertainty_score":0.2855731},"labels":[],"label_agreement":null},{"id":"W3122713579","doi":"10.21769/bioprotoc.3610","title":"Correction Notice: Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9","year":2020,"lang":"en","type":"erratum","venue":"BIO-PROTOCOL","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"CRISPR; Genome editing; Cas9; Yeast; Genetics; Computational biology; Computer science; Biology; Gene","score_opus":0.022253153085571253,"score_gpt":0.3363893798025869,"score_spread":0.31413622671701563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122713579","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005284729,0.00032433379,0.073983215,0.00014656935,0.048210073,0.84992194,0.00017060041,0.00021790802,0.026496906],"genre_scores_gemma":[0.0044942796,0.000023458171,0.0075114705,0.00037083856,0.035876807,0.91599727,0.001566886,0.00057319883,0.033585817],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975522,0.00008638913,0.0006327669,0.0008905248,0.00033343796,0.000504678],"domain_scores_gemma":[0.998901,0.000012931214,0.00028232258,0.0005210308,0.00012107613,0.00016161558],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021823509,0.00051239313,0.0004302537,0.00017592845,0.00010045635,0.00010185197,0.00035900768,0.0010108426,0.000076193224],"category_scores_gemma":[0.0002986818,0.0005508221,0.00019737484,0.0002817831,0.000048325204,0.0000073157926,0.00032804738,0.00074919,0.000030883482],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029681722,0.00017636099,0.00015611007,0.00092350465,0.000066049084,0.000048414797,0.00009365833,0.0024385676,0.5230007,0.0000010610144,0.46339196,0.009406761],"study_design_scores_gemma":[0.0009497515,0.0004086322,0.0003787541,0.0004371708,0.00003168578,0.00003279794,0.0000801318,0.008406787,0.037432637,0.0000023953485,0.9512215,0.0006177454],"about_ca_topic_score_codex":0.00006037592,"about_ca_topic_score_gemma":0.00010131853,"teacher_disagreement_score":0.48782957,"about_ca_system_score_codex":0.00014291666,"about_ca_system_score_gemma":0.0002125406,"threshold_uncertainty_score":0.99969435},"labels":[],"label_agreement":null},{"id":"W3122900175","doi":"10.1111/jre.12846","title":"The role of CRISPR‐Cas in advancing precision periodontics","year":2021,"lang":"en","type":"review","venue":"Journal of Periodontal Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Mount Sinai Hospital; McMaster University; University of Toronto","funders":"","keywords":"CRISPR; Periodontology; Periodontitis; Biology; Computational biology; Cas9; Genome editing; Gene; Genetics; Medicine","score_opus":0.0362878426151804,"score_gpt":0.46469782053247066,"score_spread":0.42840997791729024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122900175","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027655405,0.99620813,0.0003035048,0.000016344235,0.00022570205,0.00021393051,0.000007060364,8.415708e-7,0.00025893535],"genre_scores_gemma":[0.0051610204,0.9936595,0.00048717632,0.0000015587892,0.00038066733,0.0000091793545,0.000009036443,0.000041773794,0.00025009832],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972944,0.00040479202,0.00094759284,0.00022751195,0.00068948884,0.00043616298],"domain_scores_gemma":[0.99837184,0.00024523117,0.00028954897,0.00042525903,0.0005413045,0.00012679808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027325533,0.00020981957,0.00086753955,0.00024995476,0.00010754083,0.00007958083,0.00063171634,0.00028162613,0.000014692532],"category_scores_gemma":[0.0015292326,0.00014271813,0.0005543437,0.0003519817,0.000119578726,0.000005527389,0.00038538227,0.000959024,0.0000019834274],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004427394,0.00006191662,0.000102851685,0.0010135612,0.00010333884,0.00005756425,0.00015977338,0.00004477621,0.0076503726,0.000017907974,0.0003107487,0.9904329],"study_design_scores_gemma":[0.00016244176,0.00036958235,0.000052946052,0.0037375535,0.000042550477,0.0002983543,0.0010037766,0.00001598539,0.0057857516,0.000011647299,0.9883866,0.00013284283],"about_ca_topic_score_codex":0.000018957082,"about_ca_topic_score_gemma":0.000175244,"teacher_disagreement_score":0.99030006,"about_ca_system_score_codex":0.00012056523,"about_ca_system_score_gemma":0.0009524009,"threshold_uncertainty_score":0.5819876},"labels":[],"label_agreement":null},{"id":"W3123066198","doi":"10.20944/preprints201909.0340.v1","title":"Trans-Kingdom Conjugation Within Solid Media from &lt;em&gt;Escherichia coli&lt;/em&gt; to &lt;em&gt;Saccharomyces cerevisiae&lt;/em&gt;","year":2019,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BP (Canada); Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Advanced Research Projects Agency; Defense Advanced Research Projects Agency; U.S. Department of Defense","keywords":"Bacterial conjugation; Plasmid; Electroporation; DNA; Escherichia coli; Pilus; Exogenous DNA; Chemistry; Transformation (genetics); Biology; Saccharomyces cerevisiae; Cell biology; Genetics; Yeast; Gene","score_opus":0.03297714768659424,"score_gpt":0.30888341458204005,"score_spread":0.27590626689544584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123066198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9728403,0.0031676341,0.014647692,0.0003890734,0.003719066,0.0026258298,0.00070210337,0.00032482436,0.0015834464],"genre_scores_gemma":[0.9872332,0.0014019279,0.004254869,0.00059362693,0.0020818114,0.00057556684,0.0022093812,0.0003924115,0.0012572114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9908016,0.0004435415,0.002127783,0.0037415938,0.0013672354,0.0015182704],"domain_scores_gemma":[0.9934176,0.00018743785,0.0009581096,0.0038571393,0.00069286866,0.0008868189],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0016352304,0.001844983,0.001935343,0.00039351181,0.0002824886,0.00031315314,0.0024292255,0.0021199444,0.0011887664],"category_scores_gemma":[0.00087142875,0.0020398449,0.00093645824,0.0004561286,0.00018499719,0.00004659545,0.002462641,0.001543062,0.0010957972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044010507,0.0002785526,0.006720741,0.0005851409,0.0009630771,0.000031541877,0.0053430535,0.01856023,0.9640192,0.0001184603,0.0009952697,0.0019446518],"study_design_scores_gemma":[0.0031033964,0.0003308933,0.09271242,0.0011457179,0.00082642125,0.000033751545,0.000659863,0.0026986268,0.8149945,0.0006619241,0.07904314,0.0037893276],"about_ca_topic_score_codex":0.00015279207,"about_ca_topic_score_gemma":0.0011040551,"teacher_disagreement_score":0.14902465,"about_ca_system_score_codex":0.00024887608,"about_ca_system_score_gemma":0.00061958114,"threshold_uncertainty_score":0.99972427},"labels":[],"label_agreement":null},{"id":"W3124422471","doi":"10.20944/preprints202003.0048.v1","title":"CRISPR-Generated Animal Models of Duchenne Muscular Dystrophy","year":2020,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Muscular Dystrophy Canada; University of Alberta; Canadian Institutes of Health Research; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"CRISPR; Duchenne muscular dystrophy; Dystrophin; Genome editing; Neuromuscular disease; Muscular dystrophy; Computational biology; Utrophin; Medicine; Disease; Biology; Bioinformatics; Neuroscience; Genetics; Gene; Pathology","score_opus":0.0701490884528195,"score_gpt":0.34554052553882714,"score_spread":0.27539143708600766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124422471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97583526,0.0012092722,0.020684468,0.00018144315,0.0003505551,0.0004324408,0.00009768997,0.00006136645,0.0011475077],"genre_scores_gemma":[0.9966648,0.00049546466,0.0016151291,0.000069166636,0.0004568434,0.00007854453,0.00036146297,0.00008703157,0.0001715323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975688,0.00008288669,0.00057451124,0.0011403539,0.00026508785,0.00036839655],"domain_scores_gemma":[0.99802274,0.0000071561503,0.00021476598,0.0013044021,0.00024592047,0.00020500927],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022759939,0.00045536266,0.0005241242,0.0000785944,0.000042309035,0.000014308885,0.0006685116,0.000545881,0.0001088456],"category_scores_gemma":[0.0001341043,0.0005101435,0.000383271,0.00011642372,0.00008445032,0.0000039633046,0.0019931388,0.00050880364,0.00005723599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011662818,0.000075533004,0.005334941,0.0002862109,0.0003094393,0.000010939164,0.00013615718,0.06569754,0.9277252,0.000099175704,0.00012081542,0.00008744248],"study_design_scores_gemma":[0.00042248142,0.00009957519,0.012568455,0.000060454415,0.00011592535,0.0000074723093,0.00003605303,0.005861367,0.9774587,0.00036815525,0.0024909005,0.0005104269],"about_ca_topic_score_codex":0.000102996426,"about_ca_topic_score_gemma":0.0000057143084,"teacher_disagreement_score":0.059836175,"about_ca_system_score_codex":0.000026382379,"about_ca_system_score_gemma":0.0001664759,"threshold_uncertainty_score":0.999735},"labels":[],"label_agreement":null},{"id":"W3124546711","doi":"","title":"Gene Patents Still Alive and Kicking: Their Impact on Provision of Genetic Testing for Long QT Syndrome in the Canadian Public Health-Care System","year":2017,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Blueprint; Genetic testing; Context (archaeology); Long QT syndrome; Test (biology); Health care; Public health; Business; Medicine; Actuarial science; Political science; Law; Geography; Engineering; Nursing","score_opus":0.01888253919275708,"score_gpt":0.2983172221494021,"score_spread":0.27943468295664503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124546711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99124193,0.0062600314,0.0017658927,0.00027592032,0.000063531945,0.0003461651,0.000019589681,0.0000026112302,0.000024303003],"genre_scores_gemma":[0.9994089,0.0002905137,0.00012550174,0.000029835204,0.00009107853,0.000012080405,0.000014928835,0.000020451704,0.0000067059946],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983476,0.000055956516,0.000224963,0.00018808914,0.000109387925,0.0010740176],"domain_scores_gemma":[0.9992898,0.000019273159,0.00018699323,0.0002814187,0.00009829887,0.00012419563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008743015,0.0001484084,0.0001641316,0.00008635145,0.00035893393,0.00009923935,0.00031771552,0.00008089561,2.547081e-7],"category_scores_gemma":[0.000115497896,0.00009835888,0.00007053989,0.00003964491,0.000030482353,0.0000059070926,0.000032114913,0.00031295803,1.8783639e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031622752,0.00021186014,0.4904199,0.0009639491,0.0010304811,0.0001973155,0.0046645976,0.004945105,0.02780021,0.0014967874,0.000060830967,0.46789274],"study_design_scores_gemma":[0.002689372,0.0077568833,0.96658033,0.0004182278,0.00004997821,0.008041287,0.005562004,0.0019207874,0.005539118,0.0005378746,0.0003216905,0.0005824377],"about_ca_topic_score_codex":0.00416907,"about_ca_topic_score_gemma":0.054116912,"teacher_disagreement_score":0.47616044,"about_ca_system_score_codex":0.0003677655,"about_ca_system_score_gemma":0.001733588,"threshold_uncertainty_score":0.963143},"labels":[],"label_agreement":null},{"id":"W3124666661","doi":"10.1016/j.ymthe.2021.01.013","title":"Three Decades of Clinical Gene Therapy: From Experimental Technologies to Viable Treatments","year":2021,"lang":"en","type":"editorial","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Genetic enhancement; Viral vector; Stem cell; Medicine; Progenitor cell; Hematopoietic stem cell transplantation; Bioinformatics; Transplantation; Gene; Biology; Genetics; Internal medicine","score_opus":0.019399823178785042,"score_gpt":0.3789756259506313,"score_spread":0.35957580277184625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124666661","genre_codex":"empirical","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6756769,0.13165848,0.01551349,0.0000704013,0.17579947,0.00074001757,0.00033965963,0.00008916571,0.00011239641],"genre_scores_gemma":[0.4066665,0.06703084,0.047880113,0.00048002778,0.46734416,0.00091719034,0.008114639,0.0007820666,0.0007844577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977136,0.000066164124,0.00057013816,0.00088349305,0.00042701713,0.0003395832],"domain_scores_gemma":[0.9984371,0.000053872674,0.00016402033,0.0011028493,0.0001499521,0.000092198636],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016744454,0.0004737685,0.0006959205,0.00007984535,0.000043041622,0.000037411664,0.00058627536,0.0012366123,0.00003904387],"category_scores_gemma":[0.00014047924,0.00043967136,0.0004380515,0.00013725848,0.00008590573,0.0000021824617,0.00022868006,0.0002756448,0.000008037435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028959246,0.00028786456,0.00018595472,0.0000055814876,0.0009050429,0.000028903058,0.0000317957,0.00006811305,0.8963675,0.000001624298,0.08221052,0.019617515],"study_design_scores_gemma":[0.0012146796,0.0007168145,0.000047150465,0.000025944615,0.000019327665,6.200472e-7,0.000028935547,0.000004128275,0.6511915,0.000034599107,0.34643728,0.00027906304],"about_ca_topic_score_codex":0.00012137804,"about_ca_topic_score_gemma":0.000017512702,"teacher_disagreement_score":0.29154468,"about_ca_system_score_codex":0.000022957014,"about_ca_system_score_gemma":0.00019190946,"threshold_uncertainty_score":0.9998055},"labels":[],"label_agreement":null},{"id":"W3124889412","doi":"10.1126/sciadv.abc3791","title":"Safe harbor-targeted CRISPR-Cas9 homology-independent targeted integration for multimodality reporter gene-based cell tracking","year":2021,"lang":"en","type":"article","venue":"Science Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Computational biology; Bioluminescence imaging; Reporter gene; Biology; Gene; Biodistribution; Genome editing; Gene targeting; Bioinformatics; In vivo; Genetics; Luciferase; Gene expression","score_opus":0.011419723930411659,"score_gpt":0.3177280555144056,"score_spread":0.3063083315839939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124889412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.57383156,0.0036633776,0.42122203,0.00013286588,0.0006521373,0.0002460682,0.000031432053,0.00002516138,0.00019534795],"genre_scores_gemma":[0.9538561,0.000043111264,0.045442007,0.00019153755,0.00012514091,0.000050609855,0.00011034191,0.000014618996,0.00016654289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983607,0.000029546212,0.0002947484,0.00068643526,0.0002381951,0.00039040006],"domain_scores_gemma":[0.9989615,0.00002232268,0.00011421043,0.00041372114,0.00038320752,0.00010503565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047190374,0.00016989645,0.00015589413,0.00006365872,0.00022285253,0.00006384225,0.0002392608,0.000095939096,0.00001933202],"category_scores_gemma":[0.00036729634,0.00016245268,0.00010591796,0.0002535826,0.00017861898,0.00002783037,0.000056074965,0.00007994607,0.0000021245382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003426768,0.00004954854,0.00089679135,0.000022407095,0.000005271177,0.000008267214,0.00003579984,0.005549004,0.9865964,0.000007294842,0.000043022075,0.006751921],"study_design_scores_gemma":[0.00042162582,0.00013125272,0.0042185243,0.000009581697,0.000013839643,0.000011116837,0.00012874618,0.002858442,0.9871343,0.000081975864,0.0047713057,0.00021932363],"about_ca_topic_score_codex":0.000008326895,"about_ca_topic_score_gemma":0.00007167546,"teacher_disagreement_score":0.38002452,"about_ca_system_score_codex":0.000033276243,"about_ca_system_score_gemma":0.0003092997,"threshold_uncertainty_score":0.66246283},"labels":[],"label_agreement":null},{"id":"W3125152162","doi":"10.2139/ssrn.3403337","title":"Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Agence Nationale de la Recherche","keywords":"CRISPR; Allosteric regulation; Chemistry; Biochemistry; Receptor; Gene","score_opus":0.0026293095369578794,"score_gpt":0.24060571634945585,"score_spread":0.23797640681249796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125152162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980425,0.005455808,0.0128358,0.00053204317,0.00013713876,0.00022717532,0.000003471585,0.000008774356,0.00037478085],"genre_scores_gemma":[0.9951515,0.0011877526,0.000034675104,0.00013609444,0.00025175634,0.000009086668,0.00002340302,0.000025230587,0.0031804743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984689,0.000045662204,0.00016300104,0.00018578363,0.0001386489,0.0009980348],"domain_scores_gemma":[0.99963164,0.000004003856,0.00006181322,0.00021489296,0.000042162956,0.000045489433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048405986,0.00013549833,0.00009746728,0.000024297458,0.00009538849,0.000040373456,0.00016757047,0.000086749096,0.00002313689],"category_scores_gemma":[0.000017621694,0.00010052968,0.0000875153,0.000070313225,0.000022769078,0.0000053971316,0.000053047064,0.00058511866,0.000037623075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022811686,0.000021059584,0.00030863055,0.0000060473076,0.00006415997,0.0000010537027,0.000024199004,0.000105097526,0.994939,0.0004411425,0.00075865735,0.0033081209],"study_design_scores_gemma":[0.0015873798,0.001258049,0.0005576983,0.000037200083,0.00004293406,0.0018516553,0.001065981,0.00014932279,0.9167295,0.003340688,0.07286818,0.00051142706],"about_ca_topic_score_codex":0.000013391968,"about_ca_topic_score_gemma":0.000052557505,"teacher_disagreement_score":0.078209534,"about_ca_system_score_codex":0.0000716296,"about_ca_system_score_gemma":0.00026666283,"threshold_uncertainty_score":0.40994814},"labels":[],"label_agreement":null},{"id":"W3125206715","doi":"10.1038/s41551-020-00671-z","title":"In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA","year":2021,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"Novartis Stiftung für Medizinisch-Biologische Forschung; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Cytidine; RNA; RNA editing; Biology; Cytidine deaminase; Transcriptome; DNA; Genome editing; Molecular biology; Base pair; Genetics; Computational biology; Genome; Gene; Gene expression; Biochemistry; Enzyme","score_opus":0.0026166279913292403,"score_gpt":0.25029827813796635,"score_spread":0.2476816501466371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125206715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856961,0.0057073124,0.008007693,0.00014419023,0.00026152498,0.000079356556,0.000023282108,0.000012436735,0.00006812348],"genre_scores_gemma":[0.9891886,0.00012523722,0.010353395,0.000040628995,0.00019168053,0.000011470732,0.00003632422,0.000018580004,0.000034051896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991895,0.000011401427,0.00022365365,0.00022985808,0.00012878035,0.00021678291],"domain_scores_gemma":[0.99969,0.00003023157,0.000024539218,0.00012770809,0.000040090366,0.00008745437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015206504,0.00012222746,0.0001753094,0.00012273344,0.000011849734,0.000007863767,0.00006716419,0.00026770693,0.000023238166],"category_scores_gemma":[0.0005266056,0.00012955882,0.000034287303,0.0002653892,0.000028824834,0.00000607784,0.00007022094,0.000263207,2.234454e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006898439,0.000029812622,0.0013895903,0.00011158841,0.000013187508,0.000033873817,0.000044978005,0.0033477985,0.9945433,0.000022816868,0.00006600199,0.00039015024],"study_design_scores_gemma":[0.00064285117,0.00004185176,0.0014273059,0.00012355912,0.000006493945,0.000030926094,0.000053308886,0.038544167,0.952958,0.000013004449,0.0060147983,0.00014372492],"about_ca_topic_score_codex":0.000010479241,"about_ca_topic_score_gemma":0.00002533383,"teacher_disagreement_score":0.041585293,"about_ca_system_score_codex":0.000016644042,"about_ca_system_score_gemma":0.00004933129,"threshold_uncertainty_score":0.5283255},"labels":[],"label_agreement":null},{"id":"W3126007989","doi":"10.20944/preprints202007.0578.v1","title":"CRISPR-Cas12a (Cpf1): A Versatile Tool in the Plant Genome Editing Tool Box for Agricultural Advancement","year":2020,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Biology; Genome; Guide RNA; Genetics; Computer science; Biotechnology; Gene","score_opus":0.05930493480565631,"score_gpt":0.33930988375077153,"score_spread":0.28000494894511524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126007989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98264986,0.0006194037,0.012332907,0.0009238176,0.0006386374,0.0017599878,0.00030646703,0.000041209925,0.0007277033],"genre_scores_gemma":[0.99492294,0.00028805152,0.00096463546,0.00031931076,0.0013028688,0.00084258884,0.0011361883,0.0000389381,0.00018450117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781287,0.000064267384,0.0005069667,0.0009218552,0.00024295003,0.00045109756],"domain_scores_gemma":[0.99889404,0.000032989203,0.00016877505,0.00077047147,0.00007685687,0.00005689964],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004254074,0.000388963,0.00033085828,0.0000420711,0.00008696696,0.00003893538,0.00069318875,0.000275786,0.000053801854],"category_scores_gemma":[0.0002852371,0.00031881136,0.00025702248,0.00007551525,0.000034315755,0.000005294699,0.0010974418,0.00045284806,0.000042401993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001759432,0.00015774004,0.00975785,0.0006908648,0.0002708721,0.000022379223,0.0023909027,0.02095086,0.96336585,0.0002704984,0.0010423217,0.00090389344],"study_design_scores_gemma":[0.0022435125,0.00033888835,0.21966776,0.00027043757,0.00021482319,0.000050251583,0.002462866,0.0012508484,0.5807382,0.00050799246,0.1905433,0.0017111133],"about_ca_topic_score_codex":0.00003146908,"about_ca_topic_score_gemma":0.00003242419,"teacher_disagreement_score":0.38262767,"about_ca_system_score_codex":0.00006465354,"about_ca_system_score_gemma":0.000080113794,"threshold_uncertainty_score":0.9999264},"labels":[],"label_agreement":null},{"id":"W3126391152","doi":"10.1371/journal.pone.0246212","title":"Single stranded DNA annealing is a conserved activity of telomere resolvases","year":2021,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Telomere; Telomere-binding protein; DNA; Biology; Tn3 transposon; Recombinase; DNA replication; Cell biology; Molecular biology; Biochemistry; Chemistry; DNA-binding protein; Gene; Recombination; Mutant","score_opus":0.041176041714130245,"score_gpt":0.2718831991362049,"score_spread":0.23070715742207465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126391152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976152,0.0010520082,0.00048032711,0.00014015153,0.00001790372,0.00006297777,0.000039912593,0.000009957828,0.00058156863],"genre_scores_gemma":[0.9974483,0.00013045165,0.0019442801,0.00006178226,0.00006564263,0.0000044648837,0.000028490727,0.000013299137,0.00030327195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943584,0.000021182166,0.000113794165,0.00019013228,0.000106658175,0.00013238608],"domain_scores_gemma":[0.99956256,0.000014355842,0.000034326695,0.00024578837,0.000097229626,0.000045740777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045281457,0.00008333556,0.00015181424,0.000016469714,0.000024679879,0.000009181384,0.00005913894,0.00007467543,0.00005307219],"category_scores_gemma":[0.000089933266,0.000092901864,0.000058195354,0.00006806505,0.000027642158,0.0000015858645,0.000048277398,0.00004715885,0.000001568212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037886894,0.00041178052,0.000979798,0.00011622386,0.00015402006,0.0000042790834,0.000044145894,0.000016149423,0.99763864,0.0000023682978,0.00010656079,0.0004881489],"study_design_scores_gemma":[0.00035007202,0.00011660708,0.0012356181,0.00006629755,0.0000508419,0.0000028334061,0.000046214547,0.00013656527,0.99764097,0.000011432555,0.00023855527,0.000104023464],"about_ca_topic_score_codex":0.000010526209,"about_ca_topic_score_gemma":0.000033160406,"teacher_disagreement_score":0.0014639529,"about_ca_system_score_codex":0.000004528932,"about_ca_system_score_gemma":0.000043114487,"threshold_uncertainty_score":0.3788428},"labels":[],"label_agreement":null},{"id":"W3126460557","doi":"10.1016/j.ymeth.2021.01.005","title":"Production of knockout mouse lines with Cas9","year":2021,"lang":"en","type":"article","venue":"Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Toronto Centre for Phenogenomics","funders":"Canada Foundation for Innovation; Ontario Genomics","keywords":"Gene knockout; Knockout mouse; Germline; Biology; Transgene; CRISPR; Cas9; Genetics; Gene targeting; Gene; Cell biology; Electroporation; Computational biology","score_opus":0.015894479989570075,"score_gpt":0.38273292542529525,"score_spread":0.3668384454357252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126460557","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67881143,0.0013337225,0.31920993,0.00007765321,0.00016060463,0.000041453983,0.0000015876085,0.000007098478,0.00035652053],"genre_scores_gemma":[0.40445986,0.00013768199,0.5894868,0.000026976128,0.00023771306,0.00000797601,0.00002346989,0.00001706118,0.005602501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99960196,0.000051210016,0.000080204554,0.00015300701,0.000039932354,0.00007367565],"domain_scores_gemma":[0.999648,0.0000057464094,0.000020755899,0.00021722389,0.00008687766,0.000021405564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014781869,0.000057003344,0.00007799097,0.0000131887855,0.000013569591,0.00000345699,0.000035626726,0.000041291736,0.0000088961015],"category_scores_gemma":[0.00012414575,0.000048694284,0.000027917395,0.00006850353,0.000018437906,7.232341e-7,0.000028683284,0.000030549145,3.6578137e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012522233,0.000016470261,0.00033514507,0.000025219413,0.000021960086,0.0000011290858,0.000032586813,0.001397301,0.9824612,0.000008870864,0.00016562441,0.015521947],"study_design_scores_gemma":[0.00009325034,0.000059030375,0.00057226466,0.0000057498182,0.000012634323,0.000028213528,0.000058516074,0.000058030975,0.9801409,0.0000066941507,0.018901207,0.00006347131],"about_ca_topic_score_codex":0.0000040671825,"about_ca_topic_score_gemma":0.000012111379,"teacher_disagreement_score":0.27435157,"about_ca_system_score_codex":0.0000019966863,"about_ca_system_score_gemma":0.00002874523,"threshold_uncertainty_score":0.19856954},"labels":[],"label_agreement":null},{"id":"W3126821152","doi":"10.1101/2021.02.10.430527","title":"CRISPR perturbations at many coronary artery disease loci impair vascular endothelial cell functions","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Institut de Cardiologie de Montréal; Institut de Cardiologie de Montréal; Heart and Stroke Foundation of Canada; Génome Québec; Compute Canada","keywords":"Biology; CRISPR; Phenotype; Genome-wide association study; Gene; Coronary artery disease; Genetics; Furin; Endothelial stem cell; Nitric oxide; Cell biology; Single-nucleotide polymorphism; Internal medicine; Genotype; Medicine; In vitro; Biochemistry; Enzyme; Endocrinology","score_opus":0.00650690413309331,"score_gpt":0.2175959014028113,"score_spread":0.21108899726971797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126821152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9536462,0.009999458,0.033123247,0.00011824004,0.0014954017,0.0006025236,0.0008238614,0.00016933068,0.000021760483],"genre_scores_gemma":[0.99530935,0.001184219,0.0014566382,0.00029731946,0.0010491842,0.00030366305,0.000038116348,0.00017674195,0.00018477888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972713,0.00010846014,0.00045281372,0.0012514858,0.00032661288,0.00058933144],"domain_scores_gemma":[0.9971681,0.000024862038,0.00015988413,0.0017952756,0.00034227304,0.00050958496],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018946228,0.00062747055,0.0004044852,0.00013240942,0.00027261325,0.0001542636,0.00042099564,0.0005177784,0.00016660188],"category_scores_gemma":[0.00012694078,0.0007343922,0.0004954881,0.00017960773,0.000100391924,0.000010737781,0.0008798415,0.0004588379,0.000060148344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044536362,0.00021168048,0.004304969,0.0003037173,0.00028226813,0.0001051304,0.000008821767,0.0026509492,0.98939353,0.000009487554,0.0026826614,0.0000022622155],"study_design_scores_gemma":[0.0010289141,0.00011516725,0.19063537,0.00014562685,0.0005648155,2.7047722e-7,0.000019637439,0.0012231772,0.73323405,6.152174e-7,0.07146141,0.0015709589],"about_ca_topic_score_codex":0.000014490691,"about_ca_topic_score_gemma":0.0000064444453,"teacher_disagreement_score":0.25615948,"about_ca_system_score_codex":0.00016166575,"about_ca_system_score_gemma":0.00058884156,"threshold_uncertainty_score":0.9995107},"labels":[],"label_agreement":null},{"id":"W3126994555","doi":"10.1021/acs.analchem.0c04594","title":"Real-Time Optogenetics System for Controlling Gene Expression Using a Model-Based Design","year":2021,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Optogenetics; Computer science; Control system; Software; Engineering; Neuroscience; Operating system; Biology","score_opus":0.019681703949802447,"score_gpt":0.3036243986581333,"score_spread":0.28394269470833083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126994555","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23331405,0.00032316239,0.76585716,0.000016600992,0.000026488735,0.000108096654,0.00002808161,0.000024409563,0.0003019319],"genre_scores_gemma":[0.8546215,0.000021144211,0.14437762,0.000029869832,0.00027161094,0.000022399201,0.00015361536,0.000043771608,0.00045844377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988076,0.000020985104,0.0002694947,0.0004411257,0.00013798039,0.00032282626],"domain_scores_gemma":[0.99914956,0.00004293357,0.00005151527,0.00040926397,0.00018453141,0.00016221973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015380423,0.00019797783,0.00024393715,0.000013028836,0.00008064752,0.00003450522,0.00013354534,0.00023579692,0.000014038006],"category_scores_gemma":[0.00011517025,0.00020935266,0.00018593606,0.00007213535,0.000034032455,0.0000016593646,0.00005836296,0.00006709944,0.0000017066993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053783133,0.000021664113,0.000018883311,0.00009905347,0.000030919604,0.0000059344625,0.0000021509945,0.33267757,0.6669721,0.0000026019818,0.00009101102,0.000024316287],"study_design_scores_gemma":[0.0004374508,0.000013757218,9.3213356e-7,0.000030015253,0.000060224585,0.0000106794905,0.000011235701,0.47642568,0.52280754,0.0000056769195,0.00006613589,0.00013069838],"about_ca_topic_score_codex":0.000001077159,"about_ca_topic_score_gemma":8.706069e-8,"teacher_disagreement_score":0.6214796,"about_ca_system_score_codex":0.000040377934,"about_ca_system_score_gemma":0.00022400328,"threshold_uncertainty_score":0.85371536},"labels":[],"label_agreement":null},{"id":"W3127207441","doi":"10.1016/j.xpro.2021.100321","title":"Genome-scale chemogenomic CRISPR screens in human cells using the TKOv3 library","year":2021,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Canadian Cancer Society; Ontario Genomics","keywords":"CRISPR; Computational biology; Human cell; Genome; Protocol (science); Human genome; Computer science; Biology; Genome editing; Gene; Genetics","score_opus":0.01625367610660652,"score_gpt":0.3236733557676621,"score_spread":0.3074196796610556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127207441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9761948,0.0003849621,0.0037806095,0.00010403659,0.000044354325,0.017846527,0.000039769333,0.000022995902,0.0015819616],"genre_scores_gemma":[0.97629786,0.000030039188,0.00964902,0.00040093964,0.0005980521,0.010925285,0.00014362024,0.00009961517,0.0018555678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903566,0.000053716885,0.00021768415,0.000319295,0.00008886407,0.00028479035],"domain_scores_gemma":[0.99938995,0.0000054243205,0.000039377246,0.0004806837,0.00002529894,0.000059260434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011539646,0.00014943992,0.00013677486,0.000028947425,0.000087258835,0.000049797036,0.00022746481,0.00010223847,0.000103764],"category_scores_gemma":[0.0000071672525,0.00013273912,0.00008273779,0.00012625576,0.000043881508,0.0000049528944,0.00022594263,0.00012965656,0.000004574526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015249064,0.000037944297,0.001021765,0.00003876599,0.000013454986,0.000010979166,0.00007710209,0.0011896658,0.9972436,0.000011233323,0.00019937572,0.00014085807],"study_design_scores_gemma":[0.00042672892,0.000059058915,0.0030514093,0.000026165972,0.000005676804,0.000010121378,0.0001343465,0.00014389108,0.94169396,0.00004737129,0.054226194,0.0001750963],"about_ca_topic_score_codex":0.000015353577,"about_ca_topic_score_gemma":0.000043382664,"teacher_disagreement_score":0.055549666,"about_ca_system_score_codex":0.000014140378,"about_ca_system_score_gemma":0.00010285441,"threshold_uncertainty_score":0.54129446},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"methods","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"protocol","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"agree"},{"id":"W3127263521","doi":"10.1101/2021.02.05.429952","title":"Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in <i>Drosophila testis</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Robertson Foundation","keywords":"Dosage compensation; Biology; Autosome; Genetics; X chromosome; Somatic cell; Meiosis; Chromatin; Gene; Germline; Germ cell; Drosophila melanogaster; Chromosome; Y chromosome; X-inactivation","score_opus":0.012354602736459348,"score_gpt":0.23389708224126496,"score_spread":0.2215424795048056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127263521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98855966,0.00457005,0.005036187,0.0000620196,0.00087140873,0.000655905,0.00008986567,0.00011005694,0.000044861798],"genre_scores_gemma":[0.99090946,0.00044967342,0.0075438996,0.00018262037,0.00061058707,0.00011299825,0.000008309569,0.00016762866,0.0000148053805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99679565,0.00015461248,0.00074317056,0.001308219,0.0003340363,0.0006643296],"domain_scores_gemma":[0.99766934,0.00004141593,0.0003208238,0.0014112764,0.00031562292,0.00024152135],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004884378,0.0006497488,0.00061598944,0.00019706864,0.00008974877,0.00023974948,0.0005141791,0.00077018596,0.000021326749],"category_scores_gemma":[0.00032646203,0.0008118515,0.00019485567,0.00038747062,0.00008486978,0.000016637161,0.00062765327,0.0006830988,0.000010960308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014643783,0.00013450756,0.0030775606,0.00054664497,0.000049588,0.00010178652,0.000017285674,0.0055733835,0.99040854,0.000013586843,0.00006005422,0.00000242326],"study_design_scores_gemma":[0.0006124451,0.0001001383,0.02838627,0.0006188337,0.00006787234,1.9556609e-7,0.0000067559095,0.0006089267,0.96831167,0.0000018399452,0.00040373145,0.0008813298],"about_ca_topic_score_codex":0.00005677545,"about_ca_topic_score_gemma":0.000016023416,"teacher_disagreement_score":0.02530871,"about_ca_system_score_codex":0.00029122297,"about_ca_system_score_gemma":0.00050509896,"threshold_uncertainty_score":0.9994332},"labels":[],"label_agreement":null},{"id":"W3127278713","doi":"10.1101/2021.02.04.428760","title":"CRISPR-Cas9 gene editing and rapid detection of gene-edited mutants using high-resolution melting in the apple scab fungus, <i>Venturia inaequalis</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Serono Symposia International Foundation; Marsden Fund; Concordia University; Royal Society Te Apārangi; New Zealand Institute for Plant and Food Research Limited; AgResearch","keywords":"Venturia inaequalis; Biology; Apple scab; CRISPR; Genetics; Gene; Cas9; Homologous recombination; Mutant; Botany","score_opus":0.010815736155457452,"score_gpt":0.24439722939278255,"score_spread":0.2335814932373251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127278713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94934624,0.0072018956,0.04170126,0.000024523773,0.0010625063,0.00046867682,0.00015878564,0.000035066045,0.000001060244],"genre_scores_gemma":[0.99124074,0.00061922875,0.006697612,0.000060910563,0.0012233359,0.00006445542,0.000009853755,0.00008352313,3.3184594e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99749184,0.00024288993,0.00064352783,0.00083355355,0.00031894236,0.000469253],"domain_scores_gemma":[0.99837756,0.00003614441,0.0003983979,0.000802363,0.00028465688,0.00010085205],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00097094796,0.00043675746,0.00044439896,0.00015780542,0.00015028797,0.000122277,0.00032103955,0.00056110293,0.000004078783],"category_scores_gemma":[0.00027254713,0.00045430296,0.00012591976,0.00040149604,0.00008380661,0.000015082603,0.00039103074,0.00046560337,4.4714693e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026731857,0.00005967857,0.0010861784,0.00028524338,0.000086087806,0.000020340342,0.00004381137,0.0028240716,0.9955315,0.0000050657877,0.0000119445185,0.00001937357],"study_design_scores_gemma":[0.0005455015,0.000059087626,0.017455999,0.00021607366,0.000109891465,5.767556e-7,0.00007034893,0.004102564,0.97676665,4.4022366e-7,0.00024217668,0.000430719],"about_ca_topic_score_codex":0.00024896165,"about_ca_topic_score_gemma":0.000032677228,"teacher_disagreement_score":0.04189452,"about_ca_system_score_codex":0.00008157332,"about_ca_system_score_gemma":0.00017034044,"threshold_uncertainty_score":0.99979085},"labels":[],"label_agreement":null},{"id":"W3127360888","doi":"10.12688/gatesopenres.13221.2","title":"Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria","year":2021,"lang":"en","type":"preprint","venue":"Gates Open Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Open Philanthropy Project; World Health Organization; Silicon Valley Community Foundation; Bill and Melinda Gates Foundation","keywords":"Malaria; Gene drive; Medical research; Political science; Biotechnology; Biology; Gene; Immunology; Genetics","score_opus":0.12697424514933703,"score_gpt":0.4605490228737494,"score_spread":0.33357477772441235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127360888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911454,0.0024631324,0.00012551459,0.00061215844,0.000048839975,0.0027247348,0.0002135525,0.0000053842805,0.0026613134],"genre_scores_gemma":[0.9892125,0.0019902275,0.0055442727,0.00002489502,0.00010109978,0.00094534486,0.0013645827,0.000060872448,0.00075620506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99711907,0.00041347006,0.0003675885,0.0007769323,0.0005845079,0.0007384346],"domain_scores_gemma":[0.99798423,0.00021036925,0.00006237726,0.0007092357,0.00082179025,0.00021199539],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0054254285,0.0002516405,0.000406656,0.000229154,0.00027735048,0.0003781906,0.0014156606,0.00046743065,0.000050169583],"category_scores_gemma":[0.0004482956,0.0002586518,0.000059626,0.00026783062,0.00024563176,0.000009613431,0.003827569,0.0014566595,0.0000013156958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004950385,0.0005587003,0.00047002392,0.00040267268,0.00010229618,0.0000047549483,0.0028978854,0.00012580762,0.98142403,0.000044913795,0.012209786,0.0012640898],"study_design_scores_gemma":[0.0010450577,0.0009269061,0.0012729041,0.00035478637,0.000004939305,0.0000023445323,0.009587266,0.00051558076,0.9789719,0.00040278336,0.006608056,0.00030745752],"about_ca_topic_score_codex":0.0007902197,"about_ca_topic_score_gemma":0.00013476291,"teacher_disagreement_score":0.00668938,"about_ca_system_score_codex":0.0000843989,"about_ca_system_score_gemma":0.00026295905,"threshold_uncertainty_score":0.9999866},"labels":[],"label_agreement":null},{"id":"W3127557341","doi":"10.1139/bcb-2020-0593","title":"The endless battle between phages and CRISPR–Cas systems in <i>Streptococcus thermophilus</i>","year":2021,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Streptococcus thermophilus; Biology; Mobile genetic elements; Biogenesis; Plasmid; Genome; Cas9; Trans-activating crRNA; Computational biology; Bacteriophage; Streptococcus pyogenes; Genetics; Genome editing; Bacteria; Gene","score_opus":0.014838236622730847,"score_gpt":0.3302251451864426,"score_spread":0.3153869085637117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127557341","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0052139075,0.9936278,0.00007396608,0.00002132422,0.00023306506,0.0002810694,0.00010549537,0.000009513618,0.0004338777],"genre_scores_gemma":[0.025746638,0.97251797,0.000014230197,0.000008826947,0.0005358567,0.000118159245,0.00048719835,0.000036689977,0.000534412],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99827546,0.00013735583,0.00044661024,0.0007021446,0.000054642096,0.00038377577],"domain_scores_gemma":[0.9990485,0.00017731889,0.00014855704,0.00048303689,0.000030793908,0.00011183537],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002480612,0.00042874273,0.00078742777,0.00002926305,0.00012718017,0.000063374195,0.00026680576,0.0007775666,0.000003592171],"category_scores_gemma":[0.00005952592,0.00031375838,0.00014985734,0.00009195597,0.00020319568,0.0000014039066,0.00030586627,0.00029402532,0.0000015654182],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014464652,0.00007290786,0.00089726225,0.012592293,0.0004129272,0.000037876624,0.00005274682,0.0000049196733,0.104782216,0.000051611984,0.0013327025,0.87974805],"study_design_scores_gemma":[0.00021239422,0.000056359924,0.000018292934,0.00059453974,0.00013808101,0.000047309713,0.00008641867,0.000001540151,0.05553456,0.0000041453623,0.94291425,0.00039211026],"about_ca_topic_score_codex":0.000015882613,"about_ca_topic_score_gemma":0.0000037250936,"teacher_disagreement_score":0.94158155,"about_ca_system_score_codex":0.000019820453,"about_ca_system_score_gemma":0.00010825257,"threshold_uncertainty_score":0.99993145},"labels":[],"label_agreement":null},{"id":"W3127746760","doi":"10.1038/s41580-021-00343-z","title":"Towards responsible communication of agricultural biotechnology research for the common good","year":2021,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Agricultural biotechnology; Agriculture; Biotechnology; Business; CRISPR; Pipeline (software); Engineering; Biology; Genetics; Gene","score_opus":0.04325281070303981,"score_gpt":0.4446992105504384,"score_spread":0.40144639984739855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127746760","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000019952964,0.99471205,0.0016049839,0.0003057691,0.00024300785,0.002244642,0.000092923416,0.000012429521,0.00076424755],"genre_scores_gemma":[0.00031350736,0.99337924,0.0033613339,0.00006551988,0.00013230057,0.0005939187,0.0018269978,0.00005728042,0.0002698814],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99623376,0.0015871685,0.00086452585,0.0006862375,0.0001425198,0.00048575932],"domain_scores_gemma":[0.99693644,0.00034300506,0.0004174078,0.0019234439,0.00031817984,0.0000614955],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0021011143,0.0004606328,0.0016784355,0.00017369633,0.00014961214,0.000020801393,0.0014126481,0.0026158146,0.000009287707],"category_scores_gemma":[0.00082061294,0.00028235628,0.0010497455,0.00067364366,0.00029356143,0.0000016915369,0.000719724,0.0015322765,0.0000068472827],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000993774,0.000061245206,4.449033e-7,0.0056786477,0.00025176167,0.000001652045,0.00001080824,0.000006610256,0.046681885,0.0037024203,0.0042776666,0.9393169],"study_design_scores_gemma":[0.00014591776,0.000225266,9.3314975e-7,0.0014560863,0.00036449832,0.000030988074,0.000020413801,0.0000011823728,0.045342904,0.00004945618,0.95208466,0.0002777189],"about_ca_topic_score_codex":0.000010591004,"about_ca_topic_score_gemma":0.000027385606,"teacher_disagreement_score":0.94780695,"about_ca_system_score_codex":0.000041131185,"about_ca_system_score_gemma":0.0003339243,"threshold_uncertainty_score":0.99996287},"labels":[],"label_agreement":null},{"id":"W3128144765","doi":"10.1101/2021.02.07.430165","title":"Loss of PABPC1 is compensated by elevated PABPC4 and correlates with transcriptome changes","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Canadian Institutes of Health Research","keywords":"Gene isoform; Polyadenylation; Transcriptome; HEK 293 cells; Biology; Cell biology; Translation (biology); Poly(A)-binding protein; Messenger RNA; Molecular biology; Gene; Genetics; Gene expression","score_opus":0.006218045077493819,"score_gpt":0.2186767620210922,"score_spread":0.21245871694359839,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128144765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98647,0.009358636,0.0030198798,0.00014518402,0.00023167413,0.0003389169,0.00037662106,0.00005609651,0.000003003637],"genre_scores_gemma":[0.9961179,0.0022672785,0.001211486,0.00014578323,0.00008590626,0.000049739443,0.000008971844,0.000103232866,0.000009718747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982473,0.0000554429,0.00031578523,0.0008003995,0.00020775259,0.0003732701],"domain_scores_gemma":[0.998533,0.000013432446,0.00018708961,0.00073300453,0.0003589105,0.00017455382],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016482806,0.00046993452,0.00051028916,0.00008779099,0.000054545006,0.00007009427,0.00024900012,0.00053948385,0.000024178795],"category_scores_gemma":[0.000030229163,0.00047509384,0.00008019826,0.00021657516,0.00015763575,0.000004612025,0.00020336536,0.0003400914,0.0000012065709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050124454,0.000068036476,0.007905361,0.00040898705,0.00032151362,0.000017681723,0.000025758582,0.0000645864,0.9908877,0.000006777956,0.00024138881,0.0000020547031],"study_design_scores_gemma":[0.000670225,0.00018262707,0.015535144,0.00029817526,0.00013764459,1.4131399e-7,0.000012990676,0.0001847573,0.98003906,1.3750514e-7,0.0023632012,0.00057590054],"about_ca_topic_score_codex":0.00003638513,"about_ca_topic_score_gemma":0.000008501982,"teacher_disagreement_score":0.010848674,"about_ca_system_score_codex":0.000020183932,"about_ca_system_score_gemma":0.00015555862,"threshold_uncertainty_score":0.9997701},"labels":[],"label_agreement":null},{"id":"W3128946677","doi":"10.3389/fgene.2020.627673","title":"Targeted Gene Editing in Porcine Spermatogonia","year":2021,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Transcription activator-like effector nuclease; Genome editing; CRISPR; Biology; Germline; Zinc finger nuclease; Cas9; Homology directed repair; Gene; Transgene; Computational biology; Genetics; Stem cell; Gene targeting; Genetic enhancement; DNA repair","score_opus":0.004172038652041871,"score_gpt":0.24965879603136804,"score_spread":0.24548675737932615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128946677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93204355,0.020576045,0.04513618,0.00013311878,0.0013349212,0.000120963145,0.0000159292,0.000011645357,0.000627657],"genre_scores_gemma":[0.9333374,0.0016557772,0.0638082,0.00017302825,0.00042980205,0.000011901065,0.00018446102,0.000036463767,0.0003629911],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988712,0.00003758941,0.0002867369,0.00034575324,0.000112681766,0.00034600392],"domain_scores_gemma":[0.99952185,0.0000034846696,0.00003413357,0.00032281652,0.000047293957,0.00007040617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011777218,0.00015747822,0.00018681015,0.000093502735,0.000022039441,0.0000164314,0.00014244179,0.00015528082,0.00001708729],"category_scores_gemma":[0.000066367335,0.00019088993,0.000053067848,0.00024361664,0.000029558258,0.0000019320767,0.000110724606,0.00013309941,0.0000028671793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019845129,0.0000697384,0.3141317,0.000036554313,0.000029241877,0.0001298247,0.00014172483,0.018200465,0.65300745,0.0000061107453,0.008719655,0.005507687],"study_design_scores_gemma":[0.0009760341,0.000046521192,0.056263905,0.000026209596,0.000009555778,0.000040955743,0.000337769,0.0046230434,0.90958774,0.00008530817,0.027703062,0.0002998823],"about_ca_topic_score_codex":0.0000058069386,"about_ca_topic_score_gemma":0.00006971935,"teacher_disagreement_score":0.2578678,"about_ca_system_score_codex":0.000027641861,"about_ca_system_score_gemma":0.00007358927,"threshold_uncertainty_score":0.7784266},"labels":[],"label_agreement":null},{"id":"W3128966077","doi":"10.3390/iecps2020-08887","title":"Mutation of MsSPL8 Alleles via CRISPR/Cas9-Mediated Genome Editing Leads to Superior Abiotic Stress Resiliency and Distinct Morphological Alterations in Alfalfa","year":2020,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"","keywords":"Biology; Genome editing; CRISPR; Abiotic stress; Cas9; Biotechnology; Germplasm; Abiotic component; Agronomy; Crop; Genetically modified crops; Transgene; Genetics; Gene; Ecology","score_opus":0.00930104312440439,"score_gpt":0.2736995577622926,"score_spread":0.2643985146378882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128966077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.961912,0.00029863996,0.036870435,0.00052440504,0.000034569402,0.0001850779,0.000043561617,0.000012802275,0.000118544354],"genre_scores_gemma":[0.9974416,0.00002746115,0.0019602405,0.00018154584,0.00013120129,0.000012942139,0.00021017398,0.000012203036,0.000022625874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991474,0.000028547978,0.0002646897,0.00029709574,0.000084443935,0.0001778264],"domain_scores_gemma":[0.99967545,0.00002146899,0.000029379946,0.00011264201,0.00004543738,0.00011563514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007005069,0.000122030855,0.0001503013,0.000041050647,0.000032729433,0.000015659802,0.00008888269,0.000085681306,0.000040303155],"category_scores_gemma":[0.00022147181,0.00011471419,0.00003088562,0.00011949897,0.000041255087,0.000004112625,0.00008251711,0.000067751775,0.0000033907656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003066035,0.00003471863,0.011304357,0.00004329916,0.000008310049,0.000015127532,0.00041226373,0.0033149135,0.9843409,0.000009893623,0.000057522513,0.000428052],"study_design_scores_gemma":[0.0010283109,0.0012528811,0.24278519,0.000033049877,0.00002908058,0.000042919488,0.0010235868,0.012267772,0.74054986,0.00001778226,0.0004934522,0.00047610342],"about_ca_topic_score_codex":0.000043626987,"about_ca_topic_score_gemma":0.00023701272,"teacher_disagreement_score":0.243791,"about_ca_system_score_codex":0.00000625987,"about_ca_system_score_gemma":0.000015113457,"threshold_uncertainty_score":0.4677909},"labels":[],"label_agreement":null},{"id":"W3129142660","doi":"10.1038/s41434-021-00227-z","title":"Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; BC Children's Hospital; University of British Columbia","funders":"Health Canada; Québec Consortium for Drug Discovery; Weston Brain Institute; Government of Canada; Fondation Brain Canada","keywords":"PAX6; Genetic enhancement; Biology; Gene delivery; Muller glia; Retina; Promoter; Stroma; Gene; Molecular biology; Gene expression; Cancer research; Immunology; Stem cell; Cell biology; Genetics; Neuroscience; Immunohistochemistry; Transcription factor; Progenitor cell","score_opus":0.01463467848948813,"score_gpt":0.2950902394436656,"score_spread":0.28045556095417745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129142660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893104,0.0074725146,0.0025275152,0.000076772805,0.00021047206,0.00027652306,0.000047264974,0.000010698576,0.000067871086],"genre_scores_gemma":[0.9916045,0.00416758,0.0027103648,0.00050030666,0.00027209756,0.000057487352,0.00011340215,0.000047645754,0.00052659545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990935,0.000038714403,0.00017213312,0.00037897742,0.000078822435,0.00023789701],"domain_scores_gemma":[0.99954695,0.000012402583,0.000035830082,0.0003014927,0.000037449106,0.00006587023],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011475944,0.00017017507,0.00016373118,0.000039952574,0.00006576432,0.000027805401,0.000091817805,0.00013133055,0.000025638277],"category_scores_gemma":[0.000010422645,0.00016416224,0.000072709925,0.000048751164,0.000033714405,0.000002200816,0.00003862254,0.0000631913,0.0000021130124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009348439,0.00007488237,0.00021546622,0.000014385831,0.000024069948,0.0000070307865,0.000092078044,0.00016630859,0.99374974,0.000006679975,0.0011128893,0.004443013],"study_design_scores_gemma":[0.0017338035,0.00036852492,0.00065213605,0.00001862424,0.000004228019,0.0000062239797,0.000041188057,0.000042183794,0.91860485,0.000031478252,0.0783108,0.00018595743],"about_ca_topic_score_codex":0.000008784687,"about_ca_topic_score_gemma":0.000017037522,"teacher_disagreement_score":0.07719791,"about_ca_system_score_codex":0.000007877616,"about_ca_system_score_gemma":0.000030334782,"threshold_uncertainty_score":0.6694342},"labels":[],"label_agreement":null},{"id":"W3129250973","doi":"10.1016/j.cell.2021.01.005","title":"Genome engineering for crop improvement and future agriculture","year":2021,"lang":"en","type":"review","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":966,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Key Research and Development Program of China; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Biology; Crop; Agriculture; Genome; Biotechnology; Computational biology; Genetics; Agronomy; Gene; Ecology","score_opus":0.006247817933106763,"score_gpt":0.2644955344608631,"score_spread":0.25824771652775635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129250973","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000042996082,0.99682176,0.0022462106,0.000007673104,0.0003135224,0.0003972066,0.00006425791,0.0000088216275,0.00009755789],"genre_scores_gemma":[0.000009637831,0.99472463,0.001389539,0.000013447254,0.001728493,0.00010818648,0.0008228357,0.000043793574,0.0011594314],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999239,0.0000055097653,0.00017357555,0.0003453234,0.000042700703,0.0001938754],"domain_scores_gemma":[0.999626,0.000005561859,0.000047448044,0.00021805272,0.000032973727,0.00006998052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043818884,0.00026018434,0.00041410307,0.00002247409,0.000028076607,0.000029474464,0.00010199275,0.00029767724,0.000006742926],"category_scores_gemma":[0.0000054078314,0.00021125517,0.00022426805,0.000046956106,0.0000058596215,6.295128e-7,0.000092054725,0.00010293712,0.0000013418605],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000026694984,0.000050850478,1.8720691e-7,0.037963513,0.0003286054,0.000009816662,0.000040890107,0.00014538162,0.235922,0.000027516719,0.0030761417,0.72243243],"study_design_scores_gemma":[0.00010685057,0.000063108106,9.03847e-7,0.00021783127,0.0001651643,0.000014462741,0.000011408462,0.0000032281462,0.0060254685,2.8036604e-7,0.9931229,0.0002684209],"about_ca_topic_score_codex":4.0954532e-7,"about_ca_topic_score_gemma":7.12726e-7,"teacher_disagreement_score":0.99004674,"about_ca_system_score_codex":0.000011563644,"about_ca_system_score_gemma":0.00004800138,"threshold_uncertainty_score":0.8614736},"labels":[],"label_agreement":null},{"id":"W3129693673","doi":"10.1089/crispr.2020.0090","title":"Self-Cutting and Integrating CRISPR Plasmids Enable Targeted Genomic Integration of Genetic Payloads for Rapid Cell Engineering","year":2021,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; National Research Council Canada","funders":"National Research Council Canada","keywords":"CRISPR; Genome editing; Biology; Plasmid; Cas9; Genome engineering; Computational biology; Gene; Genetics; Jurkat cells; Gene targeting; Locus (genetics); T cell","score_opus":0.005579151733347831,"score_gpt":0.24753095013476248,"score_spread":0.24195179840141465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129693673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6932818,0.009886719,0.29607275,0.00011607736,0.00032500585,0.00015961943,0.000012392634,0.000013576821,0.00013201138],"genre_scores_gemma":[0.9372321,0.0012518896,0.060843296,0.000055305925,0.00045432497,0.000012952912,0.000020993535,0.000037841142,0.0000913089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989347,0.000052864132,0.0003985475,0.00021374378,0.00010968012,0.00029047483],"domain_scores_gemma":[0.99929416,0.00006173107,0.0001397069,0.00021364292,0.00020363179,0.00008713797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041397513,0.00018659445,0.00019419684,0.000055291297,0.00017024613,0.000075748096,0.00016672342,0.000103989434,0.000020010466],"category_scores_gemma":[0.00019225579,0.00014854434,0.00012535282,0.00009110002,0.000026328504,0.00000751556,0.000089612775,0.00023919273,6.302844e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022220687,0.00002255749,0.00022877133,0.00009002383,0.0000651582,0.0000033340696,0.00042935874,0.003587629,0.9917393,0.000028887976,0.00036153602,0.0034212256],"study_design_scores_gemma":[0.00057036686,0.00017833324,0.0005527685,0.000041788415,0.00007844898,0.00024325427,0.00092493574,0.02117356,0.96896935,0.00006341131,0.007024525,0.00017927031],"about_ca_topic_score_codex":0.000004515492,"about_ca_topic_score_gemma":0.0000040720506,"teacher_disagreement_score":0.24395025,"about_ca_system_score_codex":0.000022296033,"about_ca_system_score_gemma":0.000096081676,"threshold_uncertainty_score":0.6057462},"labels":[],"label_agreement":null},{"id":"W3130816366","doi":"10.1016/j.exphem.2020.09.040","title":"3019 – CRISPR-BASED ENGINEERING OF A REPORTER ALLELE DEMONSTRATES THAT HLF EXPRESSION DEFINES THE HUMAN HAEMATOPOIETIC STEM CELL STATE","year":2020,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Stem cell; Haematopoiesis; Biology; Transplantation; Reporter gene; Progenitor cell; Cell biology; Blood cell; Immunology; Genetics; Gene; Gene expression; Medicine","score_opus":0.016509294555318493,"score_gpt":0.28526489393241194,"score_spread":0.2687555993770935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130816366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98146397,0.007409113,0.010396391,0.00019654614,0.000090147994,0.00023654575,0.000007128204,0.000033776236,0.00016640514],"genre_scores_gemma":[0.99863625,0.000012785362,0.0009886841,0.00015480825,0.000039073027,0.000049631522,0.00003438056,0.000035228255,0.000049142862],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989341,0.00003533042,0.00032617705,0.0003314814,0.0001199767,0.0002529147],"domain_scores_gemma":[0.99943775,0.00001951769,0.00011663836,0.00031054544,0.000024075054,0.00009146625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006349663,0.00021301706,0.00026593282,0.000026361022,0.00006307258,0.000012370938,0.00020752562,0.000103690596,0.000035480007],"category_scores_gemma":[0.000006626856,0.00017098318,0.00011707807,0.00005709083,0.00007364019,0.0000039909933,0.00012350608,0.00008291518,0.000004155564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030283925,0.000071544695,0.0021783735,0.00011083026,0.00002057472,0.000020901343,0.00033997695,0.0013363136,0.99471194,0.00008859171,0.0010722753,0.000018373585],"study_design_scores_gemma":[0.00044354578,0.00021431361,0.00015737877,0.000021155744,0.000010105686,0.00006608506,0.00058684754,0.0008751685,0.9964729,0.000004092174,0.0009673062,0.00018107796],"about_ca_topic_score_codex":0.0000071911822,"about_ca_topic_score_gemma":0.0000021364547,"teacher_disagreement_score":0.01717232,"about_ca_system_score_codex":0.000006303179,"about_ca_system_score_gemma":0.000023939638,"threshold_uncertainty_score":0.6972492},"labels":[],"label_agreement":null},{"id":"W3132774318","doi":"10.33628/jpd.2020.27.1.187","title":"PROTOPLAST AT THE TIME OF GENOME EDITING","year":2020,"lang":"en","type":"article","venue":"Journal of Plant Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Protoplast; Genome editing; Genome; Biology; Computational biology; Genetics; Computer science; Gene","score_opus":0.007575469906002075,"score_gpt":0.22987466113984117,"score_spread":0.2222991912338391,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132774318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929001,0.0005394016,0.0057573887,0.00038053308,0.00009984586,0.00012305666,0.000015731568,0.0000017698725,0.00018222706],"genre_scores_gemma":[0.99579585,0.000046779725,0.0032069113,0.0002188355,0.0004446698,0.0000040145405,0.000030206627,0.000011001381,0.00024175823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946576,0.000010121128,0.0002525312,0.000058729802,0.00012732581,0.00008550329],"domain_scores_gemma":[0.99970824,0.000009161878,0.00013716142,0.00004642213,0.000045898774,0.000053095242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015343743,0.000060089584,0.00009508206,0.000013397209,0.000029421477,0.0000047111007,0.000114462055,0.00002831186,0.000044057357],"category_scores_gemma":[0.000047047055,0.00004000175,0.000039899376,0.000028905588,0.000012093204,0.000001123873,0.000070986105,0.000056218654,0.000006618265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006339778,0.000009995954,0.00049097365,0.000028996856,0.00007558182,0.0000103313005,0.0005439808,0.0016409005,0.9922026,0.0000015404578,0.004426655,0.00050506776],"study_design_scores_gemma":[0.00033875497,0.00016917764,0.003311257,0.000029159237,0.000011805269,0.00018024583,0.00008879695,0.00008952305,0.8235677,0.0000022938286,0.17212321,0.000088086956],"about_ca_topic_score_codex":1.6537932e-7,"about_ca_topic_score_gemma":0.0000010024742,"teacher_disagreement_score":0.16863489,"about_ca_system_score_codex":0.000010022254,"about_ca_system_score_gemma":0.000069042755,"threshold_uncertainty_score":0.16312239},"labels":[],"label_agreement":null},{"id":"W3133006703","doi":"10.1093/bioinformatics/btab112","title":"Accurate deep learning off-target prediction with novel sgRNA-DNA sequence encoding in CRISPR-Cas9 gene editing","year":2021,"lang":"en","type":"article","venue":"Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Computer science; Deep learning; Encoding (memory); Recurrent neural network; Artificial intelligence; Convolutional neural network; CRISPR; Artificial neural network; Machine learning; Gene; Biology; Genetics","score_opus":0.01337359534881089,"score_gpt":0.2686154771607254,"score_spread":0.25524188181191454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133006703","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45906216,0.00081439764,0.53750116,0.0000640712,0.0003089157,0.00016419405,0.00004046997,0.000048271777,0.0019963696],"genre_scores_gemma":[0.9470291,0.00037008582,0.051765524,0.000096466545,0.00027702615,0.000014575239,0.00031141634,0.000024326862,0.00011143753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998965,0.000015395319,0.00035273572,0.00018685781,0.0001649353,0.00031504614],"domain_scores_gemma":[0.99948347,0.000014809451,0.00010821267,0.00021135937,0.00010617983,0.00007598303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019271282,0.00016971353,0.00014514408,0.000059597605,0.00009044688,0.000062365354,0.000110576504,0.00012234571,0.0000113423575],"category_scores_gemma":[0.00017131848,0.00016644185,0.00004452131,0.00018704872,0.000028407714,0.000024726132,0.000097303855,0.00017932651,0.0000043119785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030367792,0.000047936344,0.007759983,0.00019554132,0.00006210588,0.000027301461,0.0011886152,0.14940938,0.83433247,0.000033032924,0.00015648946,0.0067567714],"study_design_scores_gemma":[0.0009701451,0.00018255101,0.0028591277,0.00012204539,0.00002386491,0.00024871726,0.0020532315,0.30916834,0.67247486,0.000006152159,0.011531707,0.000359246],"about_ca_topic_score_codex":0.0000059085487,"about_ca_topic_score_gemma":0.000032804724,"teacher_disagreement_score":0.48796698,"about_ca_system_score_codex":0.000034419496,"about_ca_system_score_gemma":0.000081771046,"threshold_uncertainty_score":0.6787302},"labels":[],"label_agreement":null},{"id":"W3133068703","doi":"10.1093/synbio/ysab008","title":"Transcriptional control of <i>Clostridium autoethanogenum</i> using CRISPRi","year":2021,"lang":"en","type":"article","venue":"Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biological and Environmental Research; Office of Science; Joint Genome Institute; Suncor Energy Incorporated; U.S. Department of Energy","keywords":"Biomanufacturing; Bioprocess; CRISPR interference; Biochemical engineering; Computational biology; Metabolic engineering; CRISPR; Function (biology); Clostridium; Biotechnology; Gene; Biology; Genome editing; Cell biology; Genetics; Engineering; Bacteria","score_opus":0.011549408567955274,"score_gpt":0.31467779388227324,"score_spread":0.30312838531431796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133068703","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6511071,0.007312447,0.3398782,0.00025821637,0.0005441019,0.00010202271,0.00013764233,0.0000132007135,0.00064708514],"genre_scores_gemma":[0.99657106,0.00013865101,0.0028152377,0.00014316954,0.00015642054,0.000005955082,0.000058732974,0.000016922071,0.00009383998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991038,0.00008139669,0.0002333571,0.00029381807,0.000058947033,0.00022869735],"domain_scores_gemma":[0.999487,0.000021416328,0.000048820595,0.00027948257,0.000107088745,0.000056229164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012345143,0.0001294246,0.00019968611,0.000031777232,0.000032932967,0.000004174658,0.00011316348,0.00019391658,0.00012452496],"category_scores_gemma":[0.00007830721,0.00013022017,0.00013773797,0.000071979164,0.000118279204,0.0000010980057,0.00003665951,0.00007175373,0.000004101998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027358326,0.00004172305,0.0009254096,0.000019391955,0.00006675516,0.0000027986732,0.000015109434,0.00048651395,0.9963972,0.0011282563,0.000038162543,0.0008513353],"study_design_scores_gemma":[0.0005360412,0.00010028271,0.00038683377,0.000011805385,0.000043987984,0.00009929932,0.000039125793,0.0004889154,0.9775782,0.0002235155,0.020343713,0.00014825803],"about_ca_topic_score_codex":0.000009451143,"about_ca_topic_score_gemma":0.0000044418175,"teacher_disagreement_score":0.345464,"about_ca_system_score_codex":0.0000073249607,"about_ca_system_score_gemma":0.000117969175,"threshold_uncertainty_score":0.5310224},"labels":[],"label_agreement":null},{"id":"W3133282258","doi":"10.1111/raq.12538","title":"A comprehensive review on genetically modified fish: key techniques, applications and future prospects","year":2021,"lang":"en","type":"review","venue":"Reviews in Aquaculture","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Genetically modified organism; Transgenesis; Fish <Actinopterygii>; Commercialization; Biology; Aquaculture; Biotechnology; Computational biology; Fishery; Genetics; Gene; Business","score_opus":0.027088515175780255,"score_gpt":0.3629251665463464,"score_spread":0.3358366513705661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133282258","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[2.4439788e-7,0.9941788,0.00032057427,0.00017071003,0.00006035776,0.0041937977,0.000068493275,0.000022758864,0.0009842954],"genre_scores_gemma":[1.4942881e-7,0.9909973,0.0034184156,0.0010589048,0.0007523541,0.0022389498,0.0011766446,0.000064489395,0.00029278785],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99761343,0.00022986565,0.0008117322,0.00088955555,0.00015427131,0.00030114935],"domain_scores_gemma":[0.99863297,0.000019107958,0.00024381875,0.00088147447,0.00009189566,0.00013071731],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021605365,0.00064213754,0.0020156936,0.00006184941,0.000051039304,0.000034722685,0.00033097522,0.000633778,0.000017993965],"category_scores_gemma":[0.00005822748,0.00047173456,0.0004795548,0.00040615114,0.00004703102,0.0000021306137,0.00017017653,0.0005669684,0.000015747106],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000010545823,0.000043564258,1.5533554e-7,0.063111395,0.000044772674,0.0000070443643,0.000007025402,4.3818068e-7,0.000073492505,0.00026092425,0.011958796,0.92449135],"study_design_scores_gemma":[0.00007976648,0.000060724775,0.0000010451482,0.042719506,0.00026623494,0.00010907276,0.0000031923641,4.828196e-7,0.000065411,0.0000068207983,0.9562115,0.0004762139],"about_ca_topic_score_codex":9.359097e-7,"about_ca_topic_score_gemma":0.00000526002,"teacher_disagreement_score":0.9442527,"about_ca_system_score_codex":0.000038383245,"about_ca_system_score_gemma":0.00009326274,"threshold_uncertainty_score":0.99977344},"labels":[],"label_agreement":null},{"id":"W3133490491","doi":"10.1111/pbi.13576","title":"Advanced domestication: harnessing the precision of gene editing in crop breeding","year":2021,"lang":"en","type":"review","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; University of Saskatchewan; Global Institute for Water Security; Saskatchewan Research Council (Canada)","funders":"Saskatchewan Wheat Development Commission; Genome Prairie; Agriculture and Agri-Food Canada; Western Grains Research Foundation; Genome Canada; Alberta Wheat Commission; Ministry of Agriculture - Saskatchewan","keywords":"Biology; Domestication; CRISPR; Genome editing; Biotechnology; Introgression; Food security; Agriculture; Genetics; Gene; Ecology","score_opus":0.018622073596202826,"score_gpt":0.3280153024057504,"score_spread":0.30939322880954756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133490491","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005698468,0.9888169,0.00975907,0.00011948814,0.00051734876,0.00014940162,0.0000272347,0.00000901975,0.00003167555],"genre_scores_gemma":[0.00097518857,0.9946847,0.0037595523,0.000007915402,0.00041434393,0.0000120474015,0.00009778447,0.000026758016,0.000021695028],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986091,0.000074465126,0.0006362109,0.0002876995,0.00012869803,0.00026379948],"domain_scores_gemma":[0.9990934,0.00006469386,0.00040833667,0.0003365088,0.000060412913,0.000036638532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046285716,0.00023104466,0.0006323403,0.00021149142,0.0000995639,0.000030332174,0.00044595875,0.0006599593,0.0000074568793],"category_scores_gemma":[0.00039204102,0.00016542945,0.00019443072,0.0002751946,0.00009211783,0.000003240668,0.00016647296,0.00076379924,0.0000012083383],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004699395,0.000019581388,0.000009532671,0.00048051638,0.00007757604,0.00004363814,0.0000157966,0.00016074395,0.023156116,0.000032748238,0.00010618435,0.97589284],"study_design_scores_gemma":[0.0002711448,0.000101123835,0.000009885853,0.0071602575,0.00016051684,0.0063904603,0.00010656404,0.00006306624,0.03488132,0.000019672674,0.9505677,0.00026827012],"about_ca_topic_score_codex":0.0000012027855,"about_ca_topic_score_gemma":0.0000042602514,"teacher_disagreement_score":0.9756246,"about_ca_system_score_codex":0.00003075714,"about_ca_system_score_gemma":0.00016544471,"threshold_uncertainty_score":0.67460173},"labels":[],"label_agreement":null},{"id":"W3133530600","doi":"10.3389/fgene.2021.630506","title":"Variation, Variegation and Heritable Gene Repression in S. cerevisiae","year":2021,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Guelph","keywords":"Biology; Epigenetics; Chromatin; Genetics; Gene; Regulation of gene expression; Psychological repression; Gene expression; Epigenesis; Phenotype; Epigenomics; Computational biology; DNA methylation","score_opus":0.010973858828830653,"score_gpt":0.31641935694966794,"score_spread":0.30544549812083727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133530600","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019956821,0.96182656,0.03692635,0.0000065516815,0.00055598875,0.00036024934,0.000017222057,0.000005904812,0.00010157638],"genre_scores_gemma":[0.000119168275,0.96681803,0.032116197,0.000015285534,0.00019003972,0.000056981793,0.00040673793,0.0000518105,0.00022572165],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984098,0.00012707358,0.0005106637,0.0005845414,0.00011059358,0.0002573092],"domain_scores_gemma":[0.999307,0.000010953165,0.00011794762,0.00046241356,0.000038969025,0.00006271787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024241913,0.0002851808,0.0006971058,0.00015779329,0.000028089627,0.00004042142,0.00016032663,0.000480771,0.000006438432],"category_scores_gemma":[0.00008377813,0.0003050893,0.00009821254,0.00027291785,0.000026990096,0.0000027593182,0.00016938169,0.00020103341,8.1619623e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006124124,0.00005857242,0.001063345,0.0030300408,0.000091966846,0.000019782217,0.00011314187,0.0015897731,0.000433648,0.000011247453,0.0021912013,0.9913912],"study_design_scores_gemma":[0.00029341123,0.00003991563,0.0005111096,0.0017409137,0.00010545184,0.00002555278,0.000027086646,0.00049016194,0.00032906522,0.000043134965,0.99598044,0.00041374436],"about_ca_topic_score_codex":0.000010388489,"about_ca_topic_score_gemma":0.000013434541,"teacher_disagreement_score":0.99378926,"about_ca_system_score_codex":0.00005003684,"about_ca_system_score_gemma":0.00015139625,"threshold_uncertainty_score":0.9999401},"labels":[],"label_agreement":null},{"id":"W3133919091","doi":"10.1039/d1nr00438g","title":"A novel method to detect mutation in DNA by utilizing exponential amplification reaction triggered by the CRISPR-Cas9 system","year":2021,"lang":"en","type":"article","venue":"Nanoscale","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kootenay Association for Science & Technology","funders":"Ministry of Science and ICT, South Korea; Ministry of Science, ICT and Future Planning","keywords":"CRISPR; DNA; Cas9; Computational biology; Biology; Genetics; Molecular biology; Gene","score_opus":0.013247550770526669,"score_gpt":0.309268624709884,"score_spread":0.2960210739393573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133919091","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3562093,0.00085964956,0.6421829,0.00016400949,0.00018395198,0.00020081917,0.000029355419,0.00001747205,0.000152583],"genre_scores_gemma":[0.9931794,0.000023388433,0.0060641314,0.00007203417,0.00008539025,0.000077527926,0.00018666546,0.000019111418,0.00029235234],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999095,0.00007909092,0.00021844916,0.00031632895,0.00011991624,0.00017121606],"domain_scores_gemma":[0.9995699,0.00002433288,0.00004732135,0.00025164353,0.000058375215,0.00004845034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026327217,0.00010739389,0.00010942539,0.00003174607,0.00006281559,0.00003076726,0.00008994761,0.00012106174,0.000003516141],"category_scores_gemma":[0.00007512868,0.0001005054,0.000053581432,0.000182686,0.000008486358,0.0000039766746,0.000035997815,0.000074092204,0.00000525473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030484684,0.000023732033,0.00001161516,0.000019561778,0.000012058222,0.0000010402637,0.00009113127,0.00012486438,0.9870393,0.000008459719,0.0015669029,0.0110708345],"study_design_scores_gemma":[0.00041048016,0.000042164254,0.00060519413,0.000018965864,0.000017975173,0.00005038647,0.0006169929,0.00060699374,0.97828984,0.000002989251,0.019220375,0.0001176423],"about_ca_topic_score_codex":0.00010141588,"about_ca_topic_score_gemma":0.00006882427,"teacher_disagreement_score":0.6369701,"about_ca_system_score_codex":0.000039377304,"about_ca_system_score_gemma":0.000029159104,"threshold_uncertainty_score":0.40984914},"labels":[],"label_agreement":null},{"id":"W3134379799","doi":"10.3390/microorganisms9030512","title":"Ectopic Spacer Acquisition in Streptococcus thermophilus CRISPR3 Array","year":2021,"lang":"en","type":"article","venue":"Microorganisms","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Agencia Nacional de Investigación e Innovación","keywords":"Streptococcus thermophilus; Biology; Streptococcus pyogenes; Bacteriophage; Genetics; Microbiology; Bacteria; Staphylococcus aureus; Gene; Escherichia coli","score_opus":0.004482677697883453,"score_gpt":0.26423987860731646,"score_spread":0.259757200909433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134379799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98532766,0.0016563005,0.011145787,0.0002704302,0.00020571894,0.00010528956,0.0000114976565,0.000016475784,0.0012608402],"genre_scores_gemma":[0.9972863,0.000114363116,0.0011000311,0.00027227926,0.0002065052,0.000010135115,0.0001046583,0.000026406691,0.0008793134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926573,0.000027202404,0.00013568692,0.00029529055,0.00006249294,0.00021362501],"domain_scores_gemma":[0.9995941,0.0000053842423,0.000021212996,0.00029348413,0.000039495368,0.00004634674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055727396,0.00012555961,0.000107635366,0.000030246714,0.000030428679,0.000024581002,0.00008035642,0.000116299576,0.0002594041],"category_scores_gemma":[0.000021100393,0.00013406955,0.00005396636,0.00010672591,0.000018469824,0.0000019936933,0.000055569115,0.00007497853,0.000035404988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005757759,0.000034481083,0.0028240632,0.000012912903,0.00001320896,0.00002088825,0.00008756523,0.00011179248,0.9958178,0.000020848187,0.00040457275,0.0006461229],"study_design_scores_gemma":[0.0004030005,0.000040933508,0.02169099,0.0000131814495,0.000006523682,0.000026159996,0.000121891,0.000003957867,0.9689629,0.00008421931,0.008486246,0.00015999116],"about_ca_topic_score_codex":0.000010175602,"about_ca_topic_score_gemma":0.00011708808,"teacher_disagreement_score":0.02685488,"about_ca_system_score_codex":0.000018412276,"about_ca_system_score_gemma":0.000060489045,"threshold_uncertainty_score":0.54671973},"labels":[],"label_agreement":null},{"id":"W3134419041","doi":"10.1002/sctm.20-0520","title":"Persistence of CRISPR/Cas9 Gene Edited Hematopoietic Stem Cells Following Transplantation: A Systematic Review and Meta-Analysis of Preclinical Studies","year":2021,"lang":"en","type":"review","venue":"Stem Cells Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Canadian Blood Services; Ottawa Hospital","funders":"","keywords":"CRISPR; Biology; Stem cell; Haematopoiesis; Genome editing; Transplantation; Genetic enhancement; Progenitor cell; Immunology; Gene; Genetics; Medicine; Internal medicine","score_opus":0.11967156737676163,"score_gpt":0.4064870121227692,"score_spread":0.2868154447460076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134419041","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000024887133,0.99387616,0.0042562536,0.00009391174,0.00017407117,0.001247635,0.0003037637,0.000006516684,0.000016823667],"genre_scores_gemma":[0.0015385895,0.9972108,0.0004238005,0.000054156324,0.00006360448,0.00013814186,0.00032144767,0.000034938992,0.00021450104],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9960636,0.00038560078,0.0021975366,0.00061942806,0.00054260617,0.00019123682],"domain_scores_gemma":[0.99779785,0.0005856718,0.0006913352,0.0005353021,0.00028326438,0.000106574786],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010059676,0.0004908919,0.007118778,0.00021511695,0.000039189967,0.000005088745,0.00023208077,0.00024791367,0.00004167826],"category_scores_gemma":[0.000026273947,0.00034781985,0.0024643983,0.0006551575,0.00014512497,0.0000049817722,0.000028776929,0.00015252088,6.3413e-7],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004832975,0.000037848633,6.484133e-7,0.8660008,0.13217664,0.00001533184,0.000351292,0.00014888236,0.0008201554,0.000009677489,0.00005343909,0.0003804637],"study_design_scores_gemma":[0.00028490456,0.0001425556,4.0448677e-7,0.048575014,0.94479173,0.0000454842,0.00024217046,0.00001929638,0.0034456663,0.0000013234953,0.0021183107,0.00033314733],"about_ca_topic_score_codex":0.000002173927,"about_ca_topic_score_gemma":0.0000053790427,"teacher_disagreement_score":0.8174258,"about_ca_system_score_codex":0.000009644151,"about_ca_system_score_gemma":0.00011405634,"threshold_uncertainty_score":0.99989736},"labels":[],"label_agreement":null},{"id":"W3134544032","doi":"10.1016/j.omtn.2021.02.032","title":"Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute on Aging; Weston Brain Institute","keywords":"Amyloid precursor protein; Mutation; Biology; CRISPR; HEK 293 cells; Transmembrane protein; Genetics; Gene; Genome editing; Molecular biology; Alzheimer's disease; Disease; Medicine","score_opus":0.01144269151970417,"score_gpt":0.2817337056394549,"score_spread":0.2702910141197507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134544032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9672622,0.0010060954,0.030830078,0.00037519014,0.000058530062,0.00043513463,0.000006216106,0.0000020818325,0.000024458419],"genre_scores_gemma":[0.99616784,0.00003121625,0.0033867396,0.00023395593,0.000027619573,0.00008966336,0.00003599544,0.000014892428,0.000012049074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991831,0.00009903786,0.0002729829,0.00016844487,0.00013772401,0.00013872124],"domain_scores_gemma":[0.9995563,0.000015018638,0.00006154361,0.00029103926,0.000060858274,0.000015250402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003256353,0.00009782373,0.00009859999,0.000026356272,0.000038623064,0.00000935146,0.00021017947,0.00005869665,0.0000033940257],"category_scores_gemma":[0.000049735307,0.000062369145,0.000075170894,0.00018580876,0.000021409554,0.0000020951734,0.000047256937,0.00006222057,2.3639747e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057468827,0.00007899799,0.00006002615,0.000016979659,0.000022085042,0.0000016643804,0.0010139266,0.0050239507,0.9644259,0.000012360088,0.000007674093,0.029278934],"study_design_scores_gemma":[0.00041883165,0.00007274239,0.0058494667,0.000019304836,0.000005439361,0.000004843067,0.00067449774,0.00045244658,0.99136734,0.000058550628,0.0010058398,0.00007067479],"about_ca_topic_score_codex":0.0000065754552,"about_ca_topic_score_gemma":0.000054927164,"teacher_disagreement_score":0.02920826,"about_ca_system_score_codex":0.000014598449,"about_ca_system_score_gemma":0.00008355446,"threshold_uncertainty_score":0.25433397},"labels":[],"label_agreement":null},{"id":"W3135156099","doi":"10.1039/d0sc06973f","title":"CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules","year":2021,"lang":"en","type":"review","venue":"Chemical Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":302,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; China Scholarship Council","keywords":"CRISPR; Nucleic acid; Palindrome; Computational biology; Biology; Genome editing; Genome; Chemistry; Nanotechnology; Genetics; Gene; Materials science","score_opus":0.021375409167693794,"score_gpt":0.3416980224268022,"score_spread":0.3203226132591084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135156099","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011368726,0.84108806,0.1568023,0.000046842855,0.000058783833,0.0006859107,0.00002030841,0.00003124503,0.00012967504],"genre_scores_gemma":[0.009125595,0.9003945,0.08908416,0.0000429157,0.00019467113,0.00068885816,0.00035669818,0.000083030056,0.000029570345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981958,0.00002050826,0.00035122465,0.00090456917,0.00015043105,0.00037744266],"domain_scores_gemma":[0.99900985,0.000021888802,0.0001640012,0.0005074686,0.00016802551,0.00012873927],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031243043,0.00031292962,0.00050508423,0.00011138245,0.000111426874,0.00014351355,0.0005477257,0.00042402418,0.0000013511326],"category_scores_gemma":[0.00051264715,0.0002915614,0.000139848,0.0005219649,0.00044566765,0.0000063828847,0.0003620614,0.00020030579,0.0000014442473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000016493672,0.000022188256,0.0000013057029,0.0018854378,0.00002106581,0.0000031436166,0.000006859793,0.000010738368,0.78969866,0.0020431625,0.000030734194,0.20627506],"study_design_scores_gemma":[0.00018338168,0.0001323752,6.836614e-7,0.0016421241,0.00015346726,0.00009565908,0.00012342313,0.00019448776,0.5901271,0.0008138675,0.40579608,0.0007373182],"about_ca_topic_score_codex":0.0000017874194,"about_ca_topic_score_gemma":0.0000010438555,"teacher_disagreement_score":0.40576535,"about_ca_system_score_codex":0.000039100833,"about_ca_system_score_gemma":0.0004918186,"threshold_uncertainty_score":0.9999536},"labels":[],"label_agreement":null},{"id":"W3135612624","doi":"10.1093/nar/gkab092","title":"Anti-CRISPR AcrIF9 functions by inducing the CRISPR–Cas complex to bind DNA non-specifically","year":2021,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"CRISPR; Biology; DNA; Nucleic acid; RNA; Mutant; Binding site; Oligonucleotide; Genetics; Gene","score_opus":0.04610761306957226,"score_gpt":0.3808387619525785,"score_spread":0.3347311488830062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135612624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.957201,0.0007933991,0.031228134,0.0040193894,0.00029152478,0.00036797847,0.00007592907,0.000028026405,0.0059946356],"genre_scores_gemma":[0.99397635,0.00024891485,0.00097528775,0.0004336029,0.0005064582,0.00004750723,0.00013441614,0.000056627414,0.0036208392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976435,0.00015015349,0.0002766572,0.000646182,0.00055258995,0.00073097367],"domain_scores_gemma":[0.99826455,0.00006561318,0.000022218068,0.00094654434,0.0004356698,0.00026543002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070105813,0.00019866237,0.00019821637,0.000096363336,0.00050083146,0.00017594949,0.0005274945,0.00019909833,0.00040531598],"category_scores_gemma":[0.00033835432,0.00016920848,0.000114134324,0.00064619334,0.00015175277,0.0000058999735,0.0006046115,0.00053296896,0.0002894614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022328475,0.00006552082,0.00051394495,0.000013821737,0.0000427256,0.000012365673,0.00018260478,0.00014908306,0.8260958,0.000029172454,0.1685777,0.0042948937],"study_design_scores_gemma":[0.00028747297,0.00016900468,0.014157699,0.000015069395,0.0000080524405,0.000026792417,0.0011294386,0.00018958247,0.56828827,0.000012659805,0.41552082,0.00019516096],"about_ca_topic_score_codex":0.000045761084,"about_ca_topic_score_gemma":0.00004611662,"teacher_disagreement_score":0.25780758,"about_ca_system_score_codex":0.000044787488,"about_ca_system_score_gemma":0.00015135789,"threshold_uncertainty_score":0.69001216},"labels":[],"label_agreement":null},{"id":"W3135773061","doi":"10.1016/j.bcp.2021.114492","title":"Small nucleic acids and the path to the clinic for anti-CRISPR","year":2021,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"CRISPR; Nucleic acid; Genome editing; Computational biology; Biology; Gene; Genetics","score_opus":0.035909741793399404,"score_gpt":0.39502868808275843,"score_spread":0.35911894628935903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135773061","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006508037,0.99456584,0.0017103988,0.0006528132,0.00088984455,0.0013743805,0.00009102637,0.000013139672,0.000051778457],"genre_scores_gemma":[0.0006672422,0.99459445,0.00043877625,0.0014406914,0.0016001435,0.0005953888,0.00022643051,0.000064053085,0.00037283092],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982383,0.00018742336,0.00044127103,0.00062294415,0.00007171742,0.0004383388],"domain_scores_gemma":[0.99900866,0.00025693243,0.00010866694,0.00041997695,0.000069838316,0.00013593854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005255456,0.00036847385,0.0008608059,0.000031038784,0.00011814831,0.000032361568,0.0005353139,0.00043785147,0.00004286436],"category_scores_gemma":[0.00020842896,0.00021589323,0.0005026072,0.00012912092,0.00020410436,6.947679e-7,0.0005573008,0.0003098211,0.000018483803],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013959016,0.0001013703,0.0000010756731,0.003993643,0.0010209278,0.000007901523,0.000055039825,0.000005106539,0.032566924,0.00007663334,0.7817217,0.18031007],"study_design_scores_gemma":[0.00079947105,0.00008234297,9.1881367e-7,0.00020224405,0.00083502795,0.00005156896,0.000013259066,0.000013114766,0.007566614,0.0000058774967,0.99015266,0.00027690383],"about_ca_topic_score_codex":0.0000020462894,"about_ca_topic_score_gemma":5.4817e-7,"teacher_disagreement_score":0.20843095,"about_ca_system_score_codex":0.0000148377185,"about_ca_system_score_gemma":0.00013015672,"threshold_uncertainty_score":0.880387},"labels":[],"label_agreement":null},{"id":"W3135864904","doi":"10.1016/j.tig.2021.02.006","title":"Horizontal Gene Transfer in Vertebrates: A Fishy Tale","year":2021,"lang":"en","type":"article","venue":"Trends in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Horizontal gene transfer; Gene transfer; Gene; Genetics; Evolutionary biology; Phylogenetics","score_opus":0.009710366220604437,"score_gpt":0.2910055677024932,"score_spread":0.28129520148188875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135864904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98944145,0.005066324,0.0030215888,0.00011118675,0.00020417839,0.00004721817,0.000025141599,0.000009630449,0.002073281],"genre_scores_gemma":[0.9960346,0.00075497985,0.0019800342,0.00011638157,0.00013155305,0.000016806933,0.00019406294,0.00002967119,0.00074187573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896187,0.000033438493,0.00023727944,0.0003585552,0.0001024172,0.0003064733],"domain_scores_gemma":[0.9995775,0.0000054981547,0.000009496211,0.00031617077,0.000025874639,0.0000654613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007219623,0.00016365234,0.00016061874,0.00010816636,0.000017052202,0.000016918559,0.00013264516,0.00015915568,0.00010237309],"category_scores_gemma":[0.000013090603,0.00018892241,0.0000756221,0.00032553234,0.000029359917,0.0000017894381,0.00006192489,0.00011654448,0.000005835466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026842643,0.00014251306,0.015277167,0.00001627047,0.000022573067,0.00009709035,0.00019568724,0.0028328581,0.9587357,0.000021956288,0.0007412943,0.021890016],"study_design_scores_gemma":[0.0011738583,0.00016483979,0.031816356,0.000014890626,0.0000108250915,0.000032481577,0.00012215084,0.0012526027,0.95438784,0.00003420071,0.01068409,0.00030587325],"about_ca_topic_score_codex":0.000016070704,"about_ca_topic_score_gemma":0.0014175674,"teacher_disagreement_score":0.021584144,"about_ca_system_score_codex":0.000022897742,"about_ca_system_score_gemma":0.000048301383,"threshold_uncertainty_score":0.7704032},"labels":[],"label_agreement":null},{"id":"W3136047862","doi":"10.15252/emmm.202013228","title":"Targeted genome editing in vivo corrects a Dmd duplication restoring wild‐type dystrophin expression","year":2021,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; Duchenne Research Fund; Howard Hughes Medical Institute","keywords":"Sick child; Medical genetics; Genetics; Genome; Medicine; Library science; Biology; Pediatrics; Computer science; Gene","score_opus":0.006892709439411191,"score_gpt":0.2780164959799537,"score_spread":0.27112378654054253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136047862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.966304,0.0075782067,0.023739716,0.00040340744,0.0006651347,0.00016504014,0.000002830107,0.000027999173,0.0011136404],"genre_scores_gemma":[0.99640495,0.00023564576,0.0018049121,0.00025201935,0.000708692,0.00002138648,0.00017038701,0.000038482314,0.00036354768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871045,0.000058659403,0.00028247302,0.0004412783,0.00022014348,0.00028702035],"domain_scores_gemma":[0.9992394,0.000009532669,0.00006662508,0.00045092686,0.00011948018,0.00011407029],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019821021,0.00017986595,0.00020547266,0.00008213744,0.0000466413,0.000009683958,0.00013517223,0.0001346749,0.000067406814],"category_scores_gemma":[0.00046962267,0.00018183606,0.00004415664,0.00029136444,0.000035922323,0.0000038525404,0.00010455755,0.00015801366,0.000003794353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002156892,0.0000232083,0.00036537377,0.000031484178,0.000013740717,0.00011401439,0.00013709479,0.0020196566,0.99630654,0.000016832115,0.000560475,0.00039000442],"study_design_scores_gemma":[0.0007299557,0.00015068459,0.0025074917,0.00015011651,0.00001571154,0.000051216797,0.00018202871,0.0002627545,0.97885966,0.00002456829,0.016882299,0.00018349716],"about_ca_topic_score_codex":0.00002244088,"about_ca_topic_score_gemma":0.000014837017,"teacher_disagreement_score":0.030100903,"about_ca_system_score_codex":0.00003350479,"about_ca_system_score_gemma":0.00005962472,"threshold_uncertainty_score":0.7415059},"labels":[],"label_agreement":null},{"id":"W3136216847","doi":"10.1038/s41380-021-01052-x","title":"Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling","year":2021,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; School of Medicine, University of California, San Diego; University of California, San Diego","keywords":"Haploinsufficiency; Neurogenesis; RHOA; Biology; Cell biology; Actin cytoskeleton; Mutant; Cytoskeleton; Neuroscience; Phenotype; Signal transduction; Genetics; Gene","score_opus":0.0049606377412191845,"score_gpt":0.2741306444872448,"score_spread":0.2691700067460256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136216847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79464865,0.008427269,0.19518362,0.00081119785,0.0004690589,0.00011870716,0.000025256028,0.00003777606,0.00027845867],"genre_scores_gemma":[0.9829336,0.00044438982,0.015217706,0.00086884206,0.00016656068,0.0000098266655,0.00019210741,0.00006887319,0.000098086595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822193,0.00008117336,0.0003599515,0.0006525423,0.00022101091,0.00046339922],"domain_scores_gemma":[0.9991408,0.000012432011,0.00006587001,0.00051230256,0.000074794625,0.00019379843],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000121230805,0.00030321992,0.00024751658,0.00004185534,0.0001404252,0.000063755986,0.0001687874,0.00020112356,0.000027136455],"category_scores_gemma":[0.00009061103,0.0003298841,0.00020144277,0.00022878055,0.00008716237,0.0000060693656,0.00018029915,0.0002241893,0.0000069635194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003071463,0.00020671742,0.003452484,0.00009861315,0.00011623249,0.00011380001,0.00004454823,0.0022935974,0.9894,0.0032429139,0.00013506682,0.00086527574],"study_design_scores_gemma":[0.004007922,0.0013049048,0.03319465,0.00018807796,0.0005565061,0.0020102928,0.00064982433,0.037892167,0.91089314,0.00210481,0.00476543,0.0024322974],"about_ca_topic_score_codex":0.000010822867,"about_ca_topic_score_gemma":0.0000421547,"teacher_disagreement_score":0.18828495,"about_ca_system_score_codex":0.000015669333,"about_ca_system_score_gemma":0.0001864917,"threshold_uncertainty_score":0.9999153},"labels":[],"label_agreement":null},{"id":"W3136386787","doi":"10.1101/2021.03.16.435597","title":"Fitness costs and benefits of gene expression plasticity in rice under drought","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"York University; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Gordon and Betty Moore Foundation; Life Sciences Research Foundation; New York University Abu Dhabi; Fordham University; Zegar Family Foundation; National Science Foundation","keywords":"Biology; Gene; Selection (genetic algorithm); Housekeeping gene; Gene expression; Plasticity; Phenotypic plasticity; Natural selection; Genetics; Genome; Regulation of gene expression; Evolutionary biology; Computational biology; Computer science","score_opus":0.00962237598016844,"score_gpt":0.23804615618657268,"score_spread":0.22842378020640425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136386787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778799,0.0057682437,0.015658982,0.000017897244,0.0003176053,0.00022775804,0.0001037543,0.000021753644,0.000004114345],"genre_scores_gemma":[0.9917548,0.001066606,0.006849503,0.000037367234,0.00018003579,0.000047172827,0.0000020550592,0.000060209335,0.0000022604456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835634,0.000058467478,0.00036664563,0.0007336603,0.0001806437,0.00030422435],"domain_scores_gemma":[0.998917,0.000025993806,0.00015623886,0.00056476775,0.00020450822,0.00013149026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015478379,0.00033934004,0.0003846875,0.00010934635,0.00003835923,0.00004811283,0.0002331345,0.00051118725,0.0000063419106],"category_scores_gemma":[0.00011886069,0.00038464167,0.000072841736,0.00017769793,0.00006355117,0.0000059814224,0.0005164673,0.0002907416,7.401514e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024818066,0.000075396536,0.004388204,0.0002972662,0.00004245118,0.00000837435,0.000007976406,0.0069826525,0.988135,0.000017516282,0.000018479668,0.0000019039736],"study_design_scores_gemma":[0.0003867488,0.000030974727,0.15183105,0.0003365879,0.000028147588,4.0569287e-8,0.0000073564606,0.00015551965,0.84681225,2.0211765e-7,0.00007255524,0.0003386053],"about_ca_topic_score_codex":0.00003451688,"about_ca_topic_score_gemma":0.000009694426,"teacher_disagreement_score":0.14744283,"about_ca_system_score_codex":0.000048287508,"about_ca_system_score_gemma":0.00017587496,"threshold_uncertainty_score":0.9998605},"labels":[],"label_agreement":null},{"id":"W3136535512","doi":"10.1038/s41587-021-00868-w","title":"High-efficiency prime editing with optimized, paired pegRNAs in plants","year":2021,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":324,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Prime (order theory); Computer science; Encoding (memory); Computational biology; Biology; Mathematics; Combinatorics; Artificial intelligence","score_opus":0.0030025474588061115,"score_gpt":0.2409968545114315,"score_spread":0.2379943070526254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136535512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97511643,0.0051563242,0.017178932,0.0014879389,0.0004451535,0.00014722241,0.000016113678,0.00008490954,0.00036697258],"genre_scores_gemma":[0.9860764,0.00033563442,0.013005065,0.00014342424,0.00018185042,0.000011328348,0.00008849926,0.000022149006,0.00013565259],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989644,0.000020704287,0.00015444167,0.0004421443,0.000100638375,0.00031765824],"domain_scores_gemma":[0.9994843,0.0000101721835,0.000043100285,0.00038193527,0.00004312345,0.0000373897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009119901,0.00016051695,0.00018083134,0.0001083705,0.00003660715,0.000010792771,0.00018966236,0.0010422982,0.00001346029],"category_scores_gemma":[0.00013350796,0.00014546896,0.000036921956,0.00024792782,0.00006534399,0.0000018828828,0.00012810121,0.000540003,0.0000036606218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000779405,0.00008911391,0.00075684197,0.000017553746,0.000038934944,0.00019255548,0.000021137806,0.0017931026,0.9897143,0.00044666976,0.00042183526,0.0064299894],"study_design_scores_gemma":[0.0009536832,0.00014397173,0.0009911903,0.00002927597,0.000006811009,0.00019086496,0.00010444251,0.00020545001,0.9849903,0.000022883583,0.012169663,0.00019146946],"about_ca_topic_score_codex":0.0000109822695,"about_ca_topic_score_gemma":0.000101839076,"teacher_disagreement_score":0.011747828,"about_ca_system_score_codex":0.000015315483,"about_ca_system_score_gemma":0.00008033886,"threshold_uncertainty_score":0.8039158},"labels":[],"label_agreement":null},{"id":"W3137580340","doi":"10.1016/j.healun.2021.01.1867","title":"CRISPR/Cas9-Mediated Epigenome Editing of the IL-10 Gene for Targeted Whole Organ Gene Therapy for Lung Transplant","year":2021,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Genetic enhancement; CRISPR; Cas9; Epigenome; Gene expression; Medicine; Genome editing; Molecular biology; Gene; Cancer research; Biology; Genetics; DNA methylation","score_opus":0.006867481799709027,"score_gpt":0.2711860034974613,"score_spread":0.2643185216977523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137580340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9025824,0.0066745966,0.089286394,0.00065450394,0.00022875909,0.00025351552,0.00031381397,0.0000026006833,0.0000034160328],"genre_scores_gemma":[0.99427754,0.0032480904,0.0017761905,0.00010444893,0.0003405417,0.000006668977,0.0001784549,0.000018192306,0.000049897575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931145,0.000054778622,0.0002899357,0.00009307107,0.000105181716,0.00014558392],"domain_scores_gemma":[0.9994942,0.000080203135,0.00010658482,0.00010373445,0.00017668396,0.000038606344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038009556,0.00010134205,0.00015407993,0.000025327132,0.00012072528,0.000010997248,0.0000926484,0.000068950336,0.000006290202],"category_scores_gemma":[0.000020040232,0.00006599577,0.00012085319,0.0000626583,0.000029541374,0.000006418069,0.000004718618,0.000071430506,7.183891e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041788464,0.000021190248,0.0006461473,0.00011991053,0.00010678221,0.0000010587396,0.00074559014,0.0010456692,0.99638414,0.000002434395,0.00034593642,0.00016323042],"study_design_scores_gemma":[0.0014326626,0.00020803459,0.00742169,0.000046282414,0.00018273898,0.00015592694,0.00012295811,0.00086992956,0.9871582,0.000015331636,0.0023030476,0.000083199346],"about_ca_topic_score_codex":0.0000034036432,"about_ca_topic_score_gemma":0.000012432593,"teacher_disagreement_score":0.091695115,"about_ca_system_score_codex":0.0000053642457,"about_ca_system_score_gemma":0.00006695279,"threshold_uncertainty_score":0.26912296},"labels":[],"label_agreement":null},{"id":"W3138259909","doi":"10.1186/s13023-021-01687-7","title":"Disease monitoring programs of rare genetic diseases: transparent data sharing between academic and commercial stakeholders","year":2021,"lang":"en","type":"letter","venue":"Orphanet Journal of Rare Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Muscular Dystrophy Canada; Canada Foundation for Innovation; Ultragenyx Pharmaceutical","keywords":"Data sharing; Disease; Business; Corporate governance; Genetic data; Rare disease; Public relations; Component (thermodynamics); Medicine; Knowledge management; Computer science; Political science; Finance; Alternative medicine; Pathology; Environmental health","score_opus":0.09474679467518646,"score_gpt":0.3413796408234724,"score_spread":0.24663284614828593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138259909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7202148,0.25981197,0.002882816,0.006737421,0.0011496225,0.0007039035,0.008462926,0.000029471454,0.000007067172],"genre_scores_gemma":[0.9672622,0.010868044,0.0005090622,0.0021633995,0.009389081,0.00002034715,0.009571154,0.00015938182,0.000057348923],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971645,0.00011596602,0.00089721783,0.0007174718,0.00062144396,0.00048339262],"domain_scores_gemma":[0.99768996,0.00005754378,0.000535405,0.0010049667,0.00016608696,0.00054600544],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000081919294,0.00050704146,0.00077265524,0.00015336211,0.00007818249,0.000093860326,0.0013068997,0.00039841904,0.000021862821],"category_scores_gemma":[0.00015607862,0.0004982706,0.00032481173,0.00012951886,0.00015530532,0.000026038744,0.0004987706,0.00081397634,3.7366405e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036383024,0.00020618508,0.8569257,0.0039466913,0.001575556,0.0020855865,0.00011104521,0.00076659507,0.0041594175,2.9521422e-7,0.08518337,0.044675708],"study_design_scores_gemma":[0.0051604183,0.0012271649,0.7405927,0.00805398,0.011685411,0.0003866978,0.0008164744,0.00013392876,0.007729777,0.00009042823,0.22101624,0.0031067722],"about_ca_topic_score_codex":0.000008725009,"about_ca_topic_score_gemma":0.0000018841341,"teacher_disagreement_score":0.24894392,"about_ca_system_score_codex":0.000022954011,"about_ca_system_score_gemma":0.00034614166,"threshold_uncertainty_score":0.9997469},"labels":[],"label_agreement":null},{"id":"W3138911480","doi":"10.1093/scipol/scab014","title":"Drawing Lines in the Sand? Paths Forward for Triggering Regulation of Gene-Edited Crops","year":2021,"lang":"en","type":"article","venue":"Science and Public Policy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Extant taxon; Corporate governance; Spell; Face (sociological concept); TRACE (psycholinguistics); Emerging technologies; Political science; Biotechnology; Engineering ethics; Risk analysis (engineering); Business; Biology; Sociology; Computer science; Engineering; Evolutionary biology; Social science","score_opus":0.013287382892316481,"score_gpt":0.3198256191922592,"score_spread":0.30653823629994276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138911480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99178517,0.00058679475,0.005766827,0.0012295094,0.00007257035,0.00009394602,0.000007838529,0.0000031385678,0.00045423326],"genre_scores_gemma":[0.99862176,0.00008736521,0.0007700731,0.00017590717,0.00027139895,0.000011101391,0.000013823602,0.0000036374877,0.000044919678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994085,0.000011982661,0.00011488578,0.00016142745,0.00011798168,0.00018524315],"domain_scores_gemma":[0.9996218,0.00001670699,0.000026327754,0.00015631356,0.00014186204,0.000036970647],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004841669,0.00005183143,0.000062659434,0.0000963782,0.00008686312,0.000054911514,0.00012998864,0.00003601463,0.0000010207712],"category_scores_gemma":[0.0006454575,0.000040308332,0.000026273474,0.0004902735,0.00010351914,0.000010201014,0.000041266176,0.000024435192,8.227259e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038778585,0.000011333972,0.0010564488,0.00001780634,0.0000027735523,2.3502227e-7,0.0002551,0.00012306595,0.98433626,0.000645895,0.00010950608,0.013437716],"study_design_scores_gemma":[0.00042490542,0.00006657746,0.03497821,0.0000122677075,0.0000046229793,0.000021084456,0.00040701637,0.002475882,0.9425512,0.00045259873,0.018495029,0.000110588386],"about_ca_topic_score_codex":0.000040515395,"about_ca_topic_score_gemma":0.00003101432,"teacher_disagreement_score":0.041785028,"about_ca_system_score_codex":0.0000073542697,"about_ca_system_score_gemma":0.00029931997,"threshold_uncertainty_score":0.16437261},"labels":[],"label_agreement":null},{"id":"W3139236263","doi":"10.1186/s12896-021-00714-6","title":"Expansion of targetable sites for the ribonucleoprotein-based CRISPR/Cas9 system in the silkworm Bombyx mori","year":2021,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China","keywords":"CRISPR; Biology; Cas9; Subgenomic mRNA; Genome editing; Genetics; Ribonucleoprotein; Mutant; Gene; Mutagenesis; Genome engineering; Computational biology; Transcription activator-like effector nuclease; Bombyx; Gene targeting; Bombyx mori; RNA","score_opus":0.012417431884826656,"score_gpt":0.2752854905066799,"score_spread":0.26286805862185325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139236263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5424225,0.0119823925,0.44278732,0.0015776888,0.0002388632,0.00079437235,0.00004229724,0.00005019876,0.00010438877],"genre_scores_gemma":[0.98928136,0.00009141157,0.010182532,0.000110448964,0.00007620703,0.00012479648,0.00004274029,0.00001819018,0.000072297735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910957,0.00004032435,0.00022998212,0.00027826143,0.000090450645,0.00025143276],"domain_scores_gemma":[0.9991013,0.00007898527,0.00006384711,0.00067073305,0.00006898235,0.000016176617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002942675,0.00013355457,0.00017610576,0.000052569972,0.000072101415,0.000011652254,0.00032662073,0.00033675053,0.000005159646],"category_scores_gemma":[0.00018157862,0.00008956457,0.00010953762,0.00022477585,0.00008942216,0.000001474804,0.000086877066,0.0001310559,0.0000018847907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004293144,0.000040513252,0.0007485814,0.00018347459,0.000020432317,0.0000037044667,0.00002754624,0.0023349323,0.99307406,0.0019402443,0.00039433024,0.0011892783],"study_design_scores_gemma":[0.0004919596,0.00014248442,0.0007708422,0.000025429506,0.000023798559,0.000020669238,0.000826441,0.0065296227,0.9773355,0.00005192022,0.013669406,0.000111896945],"about_ca_topic_score_codex":0.000033104196,"about_ca_topic_score_gemma":0.00020383071,"teacher_disagreement_score":0.4468589,"about_ca_system_score_codex":0.000010697693,"about_ca_system_score_gemma":0.00008517245,"threshold_uncertainty_score":0.36523372},"labels":[],"label_agreement":null},{"id":"W3139826906","doi":"10.1038/s41586-021-03191-1","title":"The NIH Somatic Cell Genome Editing program","year":2021,"lang":"en","type":"review","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Center for Advancing Translational Sciences; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Biomedical Imaging and Bioengineering; National Eye Institute; National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Genome editing; Genome; Somatic cell; Computer science; Human genome; Computational biology; Benchmark (surveying); Data science; Biology; Genetics; Gene","score_opus":0.007245945965213635,"score_gpt":0.34214027766342725,"score_spread":0.3348943316982136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139826906","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000010828434,0.99768966,0.00007567595,0.000025319197,0.0006468,0.0004310473,0.000019563691,0.00002262763,0.0010784782],"genre_scores_gemma":[0.000054686985,0.995282,0.0006962121,0.000045762958,0.0016774872,0.000113098926,0.0005588308,0.00005445876,0.001517463],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989728,0.00004974127,0.00023791433,0.0003256137,0.0001330921,0.00028085106],"domain_scores_gemma":[0.99926805,0.000026702712,0.00010366205,0.0004900098,0.00005507774,0.000056471203],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00013984085,0.00026683472,0.000404332,0.000020827738,0.00011044318,0.00007867058,0.0003442523,0.0017367114,0.0000081443095],"category_scores_gemma":[0.00008694109,0.00017860522,0.00036363103,0.00012196295,0.000022360768,6.224201e-7,0.00016188108,0.0014302318,0.000010648864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[3.9218696e-7,0.00002248989,4.736118e-7,0.0039533786,0.00010175544,0.000009230988,0.0000073050574,0.0000059122576,0.00024254351,0.0000117902355,0.003931929,0.9917128],"study_design_scores_gemma":[0.000044848835,0.000030842308,0.0000012689885,0.00066320406,0.00013953775,0.00003517853,0.000016866778,0.0000033236631,0.00027119505,0.0000024060437,0.9985972,0.00019413442],"about_ca_topic_score_codex":3.2111745e-7,"about_ca_topic_score_gemma":0.0000030699134,"teacher_disagreement_score":0.99466527,"about_ca_system_score_codex":0.000014000442,"about_ca_system_score_gemma":0.00011939808,"threshold_uncertainty_score":0.9995592},"labels":[],"label_agreement":null},{"id":"W3140088470","doi":"10.1038/nmeth.4559","title":"Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo”","year":2018,"lang":"en","type":"letter","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"National Institutes of Health; Genome Canada","keywords":"CRISPR; Genome editing; Biology; Genetics; Computational biology; In vivo; Cas9; Mutation; Gene","score_opus":0.008265518748828115,"score_gpt":0.3940686728648473,"score_spread":0.3858031541160192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3140088470","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08648294,0.011391846,0.4911304,0.39325026,0.01151158,0.002039759,0.00064510066,0.00021385949,0.0033342375],"genre_scores_gemma":[0.01668558,0.000029201716,0.5635959,0.39358687,0.017586159,0.00039748757,0.00045383783,0.00024417098,0.007420791],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99759495,0.0006564016,0.0003365047,0.0007120172,0.00021570169,0.00048443198],"domain_scores_gemma":[0.9988163,0.00018683655,0.000072955816,0.00066659047,0.00017295092,0.000084376516],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009818897,0.00037145294,0.0003259472,0.00033214648,0.000047125624,0.000043938177,0.0003162775,0.0023082574,0.00013233644],"category_scores_gemma":[0.0018343297,0.00038045645,0.00013634723,0.0003498223,0.00004708695,0.0000024870938,0.00017461392,0.001727935,0.000013866882],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018346317,0.00000939692,0.000032103584,0.000038795686,0.00003953647,0.000102468366,0.00015555686,0.00004322064,0.3792749,4.3240982e-7,0.6191211,0.0009990551],"study_design_scores_gemma":[0.00017900286,0.00012364252,0.00044993655,0.000056767676,0.000024674013,0.000023477773,0.00002390126,0.000022884653,0.23734316,0.000023402203,0.76140225,0.00032690735],"about_ca_topic_score_codex":0.000008963569,"about_ca_topic_score_gemma":0.000034375902,"teacher_disagreement_score":0.14228117,"about_ca_system_score_codex":0.00004853599,"about_ca_system_score_gemma":0.00008481546,"threshold_uncertainty_score":0.99986476},"labels":[],"label_agreement":null},{"id":"W3141635963","doi":"10.1186/s13059-021-02320-3","title":"Response to correspondence on “Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation”","year":2021,"lang":"en","type":"letter","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; McGill University Health Centre","funders":"School of Medicine, Tokai University; School of Medicine, Indiana University; University of Texas MD Anderson Cancer Center; Wellcome Trust; Manchester Collaborative Centre for Inflammation Research; Universiteit Gent; University of Manchester; British Heart Foundation; University of Rochester; Directorate for Biological Sciences; Medical Research Council; Children’s Hospital of Wisconsin Research Institute; Medical Center, University of Rochester; University of Nebraska Medical Center","keywords":"Biology; CRISPR; Human genetics; Genetics; Allele; Computational biology; Cas9; Reproducibility; Gene; Statistics","score_opus":0.09044060469687591,"score_gpt":0.45158779301024204,"score_spread":0.3611471883133661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3141635963","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19461064,0.0024273368,0.77642983,0.020728445,0.0009516224,0.0019451663,0.002876132,0.000012516859,0.000018311199],"genre_scores_gemma":[0.35212576,0.0003899092,0.37941867,0.18220548,0.007399089,0.0025259298,0.06959324,0.00031047134,0.0060314634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967824,0.00097540184,0.000568235,0.0012570272,0.0001418081,0.00027513248],"domain_scores_gemma":[0.9974611,0.00020135393,0.00022241936,0.0013254086,0.0007402285,0.00004950268],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0029125074,0.00026671347,0.00045119453,0.00016470965,0.00003848513,0.000006950941,0.00026939195,0.00065294775,0.00009252189],"category_scores_gemma":[0.0028685268,0.00027056335,0.00022581995,0.00009013697,0.00009957897,0.0000016429013,0.0001296507,0.00020200969,0.0000035068479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005857247,0.000108686894,0.000035717083,0.00008223588,0.00013827029,9.59126e-7,0.000075927754,0.0016252857,0.9595819,0.000004657478,0.036758304,0.0010023367],"study_design_scores_gemma":[0.0009630097,0.0009419058,0.00041424937,0.000012942421,0.000051322415,0.000008220251,0.000016218482,0.0005177725,0.62020147,0.000021693118,0.37660533,0.00024587385],"about_ca_topic_score_codex":0.000007075096,"about_ca_topic_score_gemma":0.0000084031935,"teacher_disagreement_score":0.39701116,"about_ca_system_score_codex":0.000052399664,"about_ca_system_score_gemma":0.00030107645,"threshold_uncertainty_score":0.99997467},"labels":[],"label_agreement":null},{"id":"W3141666751","doi":"10.1101/2021.03.29.437221","title":"Modeling High-grade serous ovarian carcinoma using a combination of <i>in vivo</i> electroporation and CRISPR/Cas9 mediated genome editing","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Cancer Research Society; McGill University","keywords":"Ovarian cancer; Biology; Ovarian carcinoma; Cancer research; Carcinogenesis; CRISPR; Serous fluid; PTEN; Cancer; Genetics; Gene; PI3K/AKT/mTOR pathway","score_opus":0.009128646685544457,"score_gpt":0.23141857845871194,"score_spread":0.2222899317731675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3141666751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.930443,0.0025513784,0.06620411,0.000044925353,0.00029175126,0.0003561332,0.00007418486,0.00003342972,0.0000010917504],"genre_scores_gemma":[0.9922335,0.00033436978,0.0069315615,0.000037122332,0.00032424013,0.000035987476,0.0000116036545,0.00009103304,5.954261e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794126,0.000103765415,0.00056446943,0.00076590123,0.00023216916,0.00039244952],"domain_scores_gemma":[0.9987155,0.000012055176,0.0002366624,0.0005504583,0.00036496142,0.0001203442],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003898659,0.00038526766,0.0004505733,0.0002155965,0.0000737395,0.00009006451,0.00019294575,0.00051684363,0.000004564314],"category_scores_gemma":[0.0001357526,0.0004912758,0.00008230223,0.00029441586,0.000043585947,0.0000151948625,0.00029778053,0.00036189958,2.5200563e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016369497,0.000067855464,0.0028459365,0.00029063574,0.00005929925,0.000018991452,0.000019660503,0.027955446,0.9686868,0.00003505918,0.0000033157592,5.8355573e-7],"study_design_scores_gemma":[0.0007211423,0.000071173636,0.010633598,0.0001327832,0.00007721819,1.7429447e-7,0.000021397427,0.11218629,0.8756609,0.0000015016548,0.000024343264,0.00046950212],"about_ca_topic_score_codex":0.00036539417,"about_ca_topic_score_gemma":0.00003673392,"teacher_disagreement_score":0.09302597,"about_ca_system_score_codex":0.00010530796,"about_ca_system_score_gemma":0.00031421424,"threshold_uncertainty_score":0.9997539},"labels":[],"label_agreement":null},{"id":"W3141901445","doi":"10.1186/s13023-021-01804-6","title":"Genetic counseling in the context of Bangladesh: current scenario, challenges, and a framework for genetic service implementation","year":2021,"lang":"en","type":"review","venue":"Orphanet Journal of Rare Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Alberta Innovates","keywords":"Context (archaeology); Genetic counseling; Developing country; Public health; Business; Service (business); Economic growth; Genetic testing; Health care; Medicine; Marketing; Geography; Nursing; Economics; Genetics; Biology","score_opus":0.03196178154566513,"score_gpt":0.369235938443271,"score_spread":0.33727415689760587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3141901445","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0030809934,0.9940705,0.0019529692,0.000035131314,0.00020100639,0.00044911908,0.00020814249,0.0000013228321,8.233586e-7],"genre_scores_gemma":[0.005683598,0.992108,0.0014505496,0.000048248156,0.00043931467,0.000045055105,0.00019200722,0.000032453503,7.6283214e-7],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99856514,0.00014919628,0.000673682,0.0002260958,0.0001935835,0.00019228256],"domain_scores_gemma":[0.9988565,0.00015150844,0.00046197718,0.00023592082,0.00021054712,0.000083565945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001849763,0.00025064917,0.00068667316,0.00009309872,0.00002862179,0.000028909675,0.00026900222,0.00013712494,0.000013014802],"category_scores_gemma":[0.00009410332,0.00019005321,0.00028119553,0.000102236896,0.000025136209,0.0000036955894,0.00004449742,0.00016300956,2.2541275e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022136906,0.00007449268,0.00006040496,0.00843775,0.0001696926,0.00002122331,0.00040756483,0.00003784217,0.000026565169,0.000026608355,0.00021212235,0.9905036],"study_design_scores_gemma":[0.0009594647,0.00044892353,0.00075756776,0.01167142,0.0017748447,0.0005106037,0.002800139,0.000018502313,0.000074284595,0.00012585068,0.98042816,0.00043021602],"about_ca_topic_score_codex":0.0000044403623,"about_ca_topic_score_gemma":0.000043803422,"teacher_disagreement_score":0.9900734,"about_ca_system_score_codex":0.000015853868,"about_ca_system_score_gemma":0.00028936274,"threshold_uncertainty_score":0.77501446},"labels":[],"label_agreement":null},{"id":"W3143323622","doi":"10.1126/science.abb3099","title":"Imaging cell lineage with a synthetic digital recording system","year":2021,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; National Institutes of Health; Wellcome Trust; Canadian Aeronautics and Space Institute; Paul G. Allen Family Foundation; Howard Hughes Medical Institute","keywords":"Integrase; Biology; Lineage (genetic); Computational biology; Context (archaeology); Gene; Genetics; Cell biology","score_opus":0.0029339861244011296,"score_gpt":0.23423049693164194,"score_spread":0.2312965108072408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3143323622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9213318,0.00079597946,0.06761181,0.000055629807,0.00021429708,0.000051575244,0.0000051778075,0.00002638893,0.0099073155],"genre_scores_gemma":[0.99777514,0.000008043957,0.0016792808,0.000026349668,0.000064286476,0.0000029130128,0.0000037351429,0.000008289325,0.00043195824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993133,0.000004291641,0.00006993355,0.00029457072,0.00012108894,0.00019681452],"domain_scores_gemma":[0.99959683,0.000004200675,0.000017918297,0.00024271374,0.0000720068,0.000066317276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010451247,0.00006839092,0.000053682186,0.00002478336,0.000084607185,0.00010913017,0.0001406209,0.00001426643,0.0000030306219],"category_scores_gemma":[0.00003720062,0.00005955321,0.00002245385,0.00019638512,0.00009076875,0.000006586724,0.000095126554,0.000034758847,0.000007483553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029368416,0.0000084298445,0.0017329005,0.000024409062,0.0000017538777,0.000022929671,0.0000243437,0.00045469345,0.99580836,0.000015008253,0.000022569626,0.0018816612],"study_design_scores_gemma":[0.000102780934,0.000026995172,0.00031739502,0.000037672886,0.000004099656,0.00014585232,0.00029704184,0.0017945721,0.99328196,0.0000011040513,0.0038777217,0.000112827714],"about_ca_topic_score_codex":0.0000012478605,"about_ca_topic_score_gemma":0.0000014289935,"teacher_disagreement_score":0.07644332,"about_ca_system_score_codex":0.000013037482,"about_ca_system_score_gemma":0.000112031776,"threshold_uncertainty_score":0.24285094},"labels":[],"label_agreement":null},{"id":"W3146811394","doi":"10.1158/2159-8290.cd-20-1503","title":"Synthetic Lethality in Cancer Therapeutics: The Next Generation","year":2021,"lang":"en","type":"review","venue":"Cancer Discovery","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Aegera Therapeutics (Canada); Amgen (Canada); Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center; Breast Cancer Research Foundation","keywords":"Druggability; Synthetic lethality; CRISPR; Computational biology; Suppressor; Carcinogenesis; Biology; Loss function; Drug discovery; Drug development; Function (biology); Gene; Phenotype; Cancer research; Bioinformatics; Drug; DNA repair; Genetics; Pharmacology","score_opus":0.10066437342739576,"score_gpt":0.40616311811824507,"score_spread":0.3054987446908493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3146811394","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00081044534,0.9970561,0.0006929738,0.0000854254,0.00084078504,0.0003201992,0.000099553494,0.0000048878037,0.0000895886],"genre_scores_gemma":[0.0018328958,0.9952324,0.000013534241,0.00020679859,0.0011708761,0.00053942826,0.0002055444,0.000049068534,0.00074942614],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987402,0.00012915852,0.00030596147,0.00047072853,0.00011308728,0.00024084472],"domain_scores_gemma":[0.9992704,0.000021265694,0.0000966335,0.0005523707,0.000030012296,0.000029317445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014526832,0.0002864129,0.0005041086,0.000031957366,0.000047084417,0.00010190716,0.00025336578,0.00023808822,0.000041813077],"category_scores_gemma":[0.00001453297,0.00020127182,0.00028528317,0.00014436574,0.000052011354,0.0000057788916,0.00010623026,0.00022297473,0.0000024659485],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000032610092,0.000034267738,0.000040991403,0.002009553,0.00025440304,0.0000038547955,0.000048265803,0.0010797211,0.0036154136,0.000036340603,0.001001369,0.99187255],"study_design_scores_gemma":[0.00007435273,0.000012389578,0.000013905091,0.00174881,0.00026491328,0.000005813121,0.000024708645,0.00004395906,0.0015887542,0.0000025217475,0.99593943,0.00028045237],"about_ca_topic_score_codex":0.00017404051,"about_ca_topic_score_gemma":0.00071266864,"teacher_disagreement_score":0.9949381,"about_ca_system_score_codex":0.00009776773,"about_ca_system_score_gemma":0.0005104104,"threshold_uncertainty_score":0.82076263},"labels":[],"label_agreement":null},{"id":"W3146872207","doi":"10.3389/fmicb.2021.670975","title":"Editorial: Genomic Basis of Antibiotic Resistance and Virulence in Acinetobacter","year":2021,"lang":"en","type":"editorial","venue":"Frontiers in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Antibiotic resistance; Acinetobacter; Virulence; Microbiology; Biology; Antibiotics; Clinical microbiology; Genetics; Gene","score_opus":0.002095716000818828,"score_gpt":0.23229558315503412,"score_spread":0.2301998671542153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3146872207","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04729185,0.020950299,0.00054958777,0.00001689606,0.93070644,0.00016340075,0.00026743894,0.000004114978,0.000049977993],"genre_scores_gemma":[0.012805124,0.012609026,0.006244568,0.000022977396,0.9661864,0.0000116615465,0.0014509807,0.00006909995,0.00060014124],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99841255,0.000109802895,0.00043711616,0.00064092694,0.000061645485,0.0003379756],"domain_scores_gemma":[0.999321,0.000043873897,0.00013195454,0.0003805931,0.000084615924,0.00003800445],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027377612,0.00027742577,0.0005938353,0.00017608737,0.000014290736,0.000010245829,0.00026840836,0.001272031,0.000004075414],"category_scores_gemma":[0.00028617468,0.00031039643,0.000073901785,0.00012304734,0.00015653555,0.00000228906,0.00019534072,0.00041947202,6.6454766e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070459944,0.00001670679,0.0016360455,0.00013036972,0.000029043495,0.000003991166,0.00002330466,0.000019243305,0.39657575,3.1716613e-7,0.6013844,0.000110347726],"study_design_scores_gemma":[0.0007736552,0.00007898232,0.000449594,0.0002005369,0.000021799335,0.0000022385007,0.000049748025,0.0000026686432,0.06563974,0.000009950877,0.9324564,0.00031474052],"about_ca_topic_score_codex":0.000035801233,"about_ca_topic_score_gemma":0.00044031945,"teacher_disagreement_score":0.3310719,"about_ca_system_score_codex":0.00005432098,"about_ca_system_score_gemma":0.0001868151,"threshold_uncertainty_score":0.9999348},"labels":[],"label_agreement":null},{"id":"W3147137656","doi":"10.3390/molecules26072053","title":"Synergizing Off-Target Predictions for In Silico Insights of CENH3 Knockout in Cannabis through CRISPR/Cas","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Guelph","funders":"","keywords":"CRISPR; In silico; Support vector machine; Receiver operating characteristic; Random forest; Computer science; Computational biology; Classifier (UML); Machine learning; Artificial intelligence; Biology; Genetics; Gene","score_opus":0.008474096416350413,"score_gpt":0.2903165728239382,"score_spread":0.28184247640758775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147137656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85617197,0.009936808,0.1321271,0.00026316012,0.00020140494,0.00022869196,0.000042416093,0.000011481549,0.0010169542],"genre_scores_gemma":[0.99359095,0.00026609914,0.005604453,0.00008240078,0.00007105621,0.00006961764,0.000100671896,0.000022977785,0.0001917822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991385,0.000029192488,0.0002596584,0.00028672122,0.00007686657,0.00020905907],"domain_scores_gemma":[0.99959844,0.000012311375,0.00003636779,0.0002403942,0.00007724247,0.000035238198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000044880275,0.00012646717,0.00017358287,0.00006081413,0.000025859925,0.000008747569,0.00009626712,0.0001236128,0.0000052662845],"category_scores_gemma":[0.00013609034,0.00013877054,0.000083669336,0.00016883467,0.00002937668,0.000004062728,0.00006967149,0.00007194753,5.236266e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031372354,0.00012495222,0.0013340256,0.0000954818,0.000035504654,0.000017335591,0.00046276386,0.032970075,0.96253294,0.0006299145,0.0010901012,0.000675513],"study_design_scores_gemma":[0.0005984925,0.00008855801,0.006544634,0.00004901773,0.000010857957,0.00000590182,0.00027758593,0.0021887464,0.96510535,0.00039742037,0.024572669,0.0001607354],"about_ca_topic_score_codex":0.00010407557,"about_ca_topic_score_gemma":0.0011494195,"teacher_disagreement_score":0.13741896,"about_ca_system_score_codex":0.000019165424,"about_ca_system_score_gemma":0.00009173243,"threshold_uncertainty_score":0.56588984},"labels":[],"label_agreement":null},{"id":"W3147518691","doi":"","title":"Anti-CRISPRs and CRISPR-Cas: Characterization and Biotechnology","year":2019,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biotechnology; Biology; Computational biology; Genetics; Gene","score_opus":0.004270571980771745,"score_gpt":0.24612191869835226,"score_spread":0.24185134671758052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147518691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98955625,0.0031258224,0.0051599476,0.0001229485,0.0001887863,0.00016701285,0.000028387212,0.000016161028,0.0016346817],"genre_scores_gemma":[0.98297155,0.010152645,0.0003900449,0.000008556675,0.000027438431,2.286086e-7,0.0006388446,0.000018102059,0.0057926155],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994455,0.000012115465,0.00006338704,0.00029501735,0.000059948932,0.00012403414],"domain_scores_gemma":[0.99960506,0.0000037854597,0.00009691056,0.00020631,0.00004532406,0.000042611704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003963109,0.00014782591,0.00021707638,0.00003765343,0.00005080041,0.0000072979024,0.000104400075,0.00041242977,0.00018347501],"category_scores_gemma":[0.00000977225,0.00019550521,0.000041462084,0.000020547375,0.000046656118,0.000009336828,0.00006814802,0.000072191295,0.0000018262891],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064687556,0.000014244715,0.00052416883,0.00022006621,0.00007480305,0.0000022410075,0.0013191506,0.0000029504652,0.9645184,0.000054005537,0.00008500558,0.033120252],"study_design_scores_gemma":[0.0011635568,0.00051537715,0.72613645,0.00014657482,0.0002439067,0.000018313845,0.01770205,0.0004208397,0.238009,0.0000034012958,0.014913463,0.0007270856],"about_ca_topic_score_codex":0.0024803402,"about_ca_topic_score_gemma":0.0038301146,"teacher_disagreement_score":0.7265094,"about_ca_system_score_codex":0.000015190559,"about_ca_system_score_gemma":0.000026137299,"threshold_uncertainty_score":0.7972471},"labels":[],"label_agreement":null},{"id":"W3147882607","doi":"","title":"Adverse Outcome Pathway on Alkylation of DNA in Male Pre-Meiotic Germ Cells Leading to Heritable Mutations","year":2016,"lang":"en","type":"article","venue":"OECD series on adverse outcome pathways","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Health Canada","funders":"","keywords":"Germ cell; Biology; Context (archaeology); Germline; Adverse Outcome Pathway; Genetics; Meiosis; Mutation; Somatic cell; DNA damage; DNA; Gene; Computational biology","score_opus":0.01669297385173359,"score_gpt":0.2853784118132483,"score_spread":0.26868543796151473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147882607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918802,0.000023709692,0.0027590825,0.0001726384,0.00042411478,0.00043748593,0.00015148705,0.000035615147,0.0041156965],"genre_scores_gemma":[0.99082524,0.000018521827,0.001295148,0.00018961586,0.00007391052,0.000046160323,0.00004257726,0.000050578594,0.0074582426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982624,0.00004848768,0.00056687143,0.0004745181,0.00022803804,0.00041968533],"domain_scores_gemma":[0.99906063,0.00005333202,0.00013189967,0.00055132376,0.00005439098,0.00014839333],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021740417,0.00029553135,0.00034013315,0.00019106075,0.00006734658,0.000008916232,0.00020563453,0.0001671774,0.00015066244],"category_scores_gemma":[0.0001316411,0.00025574607,0.00016100325,0.00013687562,0.00005579899,0.000021973878,0.000091988615,0.000103141305,0.00024897786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019351082,0.00011001857,0.0212276,0.00007149081,0.00002365885,0.000018074948,0.0002678381,0.013612282,0.96267146,0.00049985223,0.00009133119,0.0012129068],"study_design_scores_gemma":[0.0012930465,0.00076102506,0.027865468,0.00010658776,0.000017835402,0.0000093085555,0.0003915988,0.000058069014,0.958755,0.00003694709,0.01022581,0.00047926002],"about_ca_topic_score_codex":0.000015740543,"about_ca_topic_score_gemma":0.00012334767,"teacher_disagreement_score":0.013554214,"about_ca_system_score_codex":0.00008451121,"about_ca_system_score_gemma":0.000047398655,"threshold_uncertainty_score":0.99998945},"labels":[],"label_agreement":null},{"id":"W3148527842","doi":"10.1111/pbi.13597","title":"Expert opinions on the regulation of plant genome editing","year":2021,"lang":"en","type":"review","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canada First Research Excellence Fund","keywords":"Food security; Biology; Genome editing; Agriculture; Poverty; Biotechnology; Genome; Natural resource economics; Economic growth; Ecology; Economics; Genetics; Gene","score_opus":0.02611960872692784,"score_gpt":0.3114541777510581,"score_spread":0.28533456902413024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3148527842","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005275071,0.99676305,0.0016390452,0.00037457386,0.0005534439,0.00016147525,0.0003724579,0.000012935999,0.00007024907],"genre_scores_gemma":[0.00017468854,0.9974719,0.00035295196,0.000032638472,0.00083890685,0.000014863535,0.001041861,0.000028382265,0.000043802065],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988173,0.00008097267,0.00047322895,0.00025440645,0.00013044458,0.00024362946],"domain_scores_gemma":[0.99912703,0.000054924356,0.00033301918,0.00040452142,0.00003657493,0.00004392954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002702145,0.00024809214,0.0005541734,0.0001598785,0.00012643155,0.000019704758,0.00039301027,0.00075065374,0.00003253779],"category_scores_gemma":[0.00014818757,0.00016564436,0.00029149232,0.00012582392,0.000079243226,0.0000011868447,0.00013700071,0.0006559229,0.0000042642805],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029844141,0.00018621974,0.000003419768,0.0018814879,0.001860536,0.00011897187,0.000104621104,0.00026748423,0.071806125,0.0044934284,0.027652934,0.89159495],"study_design_scores_gemma":[0.00007272123,0.0001027815,0.000002436154,0.0019305504,0.00006910602,0.0023595525,0.000050349663,0.000010193748,0.008338995,0.000011071218,0.9868899,0.00016234671],"about_ca_topic_score_codex":0.0000012529882,"about_ca_topic_score_gemma":0.0000022102427,"teacher_disagreement_score":0.959237,"about_ca_system_score_codex":0.000022508762,"about_ca_system_score_gemma":0.00012166977,"threshold_uncertainty_score":0.6754781},"labels":[],"label_agreement":null},{"id":"W3149158769","doi":"10.1128/mbio.03338-20","title":"Cooperation between Different CRISPR-Cas Types Enables Adaptation in an RNA-Targeting System","year":2021,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Koneen Säätiö; Government of Canada; Jane ja Aatos Erkon Säätiö; Academy of Finland; Natural Sciences and Engineering Research Council of Canada; European Commission; U.S. Department of Agriculture","keywords":"CRISPR; Adaptation (eye); RNA; Computational biology; Computer science; Biology; Genetics; Gene; Neuroscience","score_opus":0.014191496727955118,"score_gpt":0.2870304109158798,"score_spread":0.27283891418792466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3149158769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9606006,0.0009922405,0.037980415,0.000044272372,0.000119762684,0.00006493615,0.000007167443,0.000014974048,0.00017562372],"genre_scores_gemma":[0.99854606,0.000034220422,0.00065009913,0.000024059542,0.00022589325,0.000009138169,0.00038537598,0.000013019485,0.00011215606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941975,0.000043639153,0.00014867938,0.00019962547,0.00005867207,0.00012962657],"domain_scores_gemma":[0.999739,0.0000062345975,0.000020801835,0.00013621474,0.0000584014,0.000039350623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075256336,0.00008523441,0.00009549468,0.0000231024,0.00003816347,0.000032173848,0.000050321483,0.000079941026,0.000008166972],"category_scores_gemma":[0.000030853334,0.000084755055,0.00002464447,0.00005579303,0.000006782799,0.0000036671324,0.000030382269,0.00004764816,0.0000039209212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008335472,0.000025258709,0.01690267,0.000056124176,0.000016072974,0.000006655706,0.00020226382,0.0044611483,0.97478783,0.00007624665,0.000119509124,0.003337863],"study_design_scores_gemma":[0.0002553495,0.00006945007,0.021532571,0.000023683062,0.000013051865,0.0000028801844,0.00054586714,0.0036807223,0.9724417,0.0000048158154,0.001290523,0.00013941196],"about_ca_topic_score_codex":0.00003106465,"about_ca_topic_score_gemma":0.0002799697,"teacher_disagreement_score":0.03794543,"about_ca_system_score_codex":0.000019956942,"about_ca_system_score_gemma":0.000024031819,"threshold_uncertainty_score":0.34562108},"labels":[],"label_agreement":null},{"id":"W3149550419","doi":"","title":"Consumers’ Willingness-To-Pay for RNAi versus Bt Rice: Are all biotechnologies the same?","year":2016,"lang":"en","type":"article","venue":"2016 Annual Meeting, July 31-August 2, Boston, Massachusetts","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"RNA interference; Biotechnology; Agriculture; Genetically modified organism; Pest control; Genetically modified crops; Pesticide; Willingness to pay; Biology; Bacillus thuringiensis; Business; Agricultural science; Economics; Gene; Ecology; Transgene; Genetics; RNA","score_opus":0.014517897712055817,"score_gpt":0.2939055439859292,"score_spread":0.2793876462738734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3149550419","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90827644,0.008111488,0.03869058,0.02659573,0.0055247834,0.003666233,0.00311404,0.0009400389,0.0050806375],"genre_scores_gemma":[0.9838021,0.0010243148,0.0027741585,0.0009532226,0.0006995944,0.00029294103,0.00010225736,0.00015740027,0.010194018],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99728453,0.000067083776,0.0004890858,0.0008911555,0.0003041639,0.0009639676],"domain_scores_gemma":[0.9978603,0.0002486558,0.0002689751,0.0010224447,0.00037070978,0.00022888434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00056499196,0.00052985107,0.00038820747,0.0001120981,0.00027353238,0.000073586285,0.000896739,0.0005395847,0.000018476876],"category_scores_gemma":[0.0015599211,0.0003158672,0.00022123952,0.00022377526,0.00021746059,0.00001966571,0.00038858916,0.00023929383,0.00013192743],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009340133,0.0001283125,0.005404808,0.00012202406,0.0004365899,0.000012433438,0.00035823588,0.00018543823,0.4958753,0.00014117666,0.4859293,0.010472357],"study_design_scores_gemma":[0.0018059325,0.0004931399,0.0031420798,0.00013431489,0.00010238863,0.000011675768,0.00055453007,0.000010585822,0.20565233,0.00006610539,0.78740466,0.000622288],"about_ca_topic_score_codex":0.000063230815,"about_ca_topic_score_gemma":0.00008332814,"teacher_disagreement_score":0.30147532,"about_ca_system_score_codex":0.00005974718,"about_ca_system_score_gemma":0.00012451796,"threshold_uncertainty_score":0.99992937},"labels":[],"label_agreement":null},{"id":"W3151024940","doi":"10.1101/2021.04.08.438361","title":"CCNE1 amplification is synthetic-lethal with PKMYT1 kinase inhibition","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Telesta Therapeutics (Canada); Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cyclin E1; Cyclin-dependent kinase 1; FOXM1; Synthetic lethality; Cancer research; Mitosis; Biology; Cyclin; Cell cycle; Gene; Cell biology; DNA repair; Genetics","score_opus":0.008112031588759085,"score_gpt":0.23432311631412803,"score_spread":0.22621108472536894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3151024940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9503912,0.0020934567,0.046211977,0.00019529069,0.0004261363,0.00041908977,0.00013884433,0.00010212119,0.000021906746],"genre_scores_gemma":[0.9916068,0.0003915264,0.0069684535,0.0001965706,0.0005044333,0.00017787569,0.000008526472,0.00013404251,0.000011782007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772495,0.00006967815,0.000356984,0.0011319547,0.00029030698,0.0004260986],"domain_scores_gemma":[0.9977278,0.000011080269,0.0001990953,0.0014209381,0.00043344547,0.0002076407],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024418742,0.0004960409,0.00034295744,0.00011376624,0.000107113825,0.00018640533,0.0002562973,0.0005821451,0.000044261422],"category_scores_gemma":[0.00008485944,0.0005349093,0.00014858908,0.00021835502,0.00009409184,0.0000082050965,0.00032376143,0.00041240852,0.000018406281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032613643,0.00009852624,0.00074125733,0.00023368174,0.00011966736,0.00003955565,0.00001190568,0.00039925292,0.99800026,0.000039600873,0.00027773235,0.0000059339163],"study_design_scores_gemma":[0.00037680898,0.00008966324,0.010870389,0.00030081067,0.000103518534,1.7658348e-7,0.0000102200975,0.00016232529,0.98235637,4.720678e-7,0.0050405967,0.00068863324],"about_ca_topic_score_codex":0.000023841576,"about_ca_topic_score_gemma":0.000004252325,"teacher_disagreement_score":0.04121561,"about_ca_system_score_codex":0.00007079163,"about_ca_system_score_gemma":0.00034663663,"threshold_uncertainty_score":0.99971026},"labels":[],"label_agreement":null},{"id":"W3151926724","doi":"10.1007/s00439-021-02272-5","title":"Addressing the dark matter of gene therapy: technical and ethical barriers to clinical application","year":2021,"lang":"en","type":"review","venue":"Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome Canada; Université Laval; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Genome editing; Engineering ethics; Rigour; CRISPR; Genetic enhancement; Bioethics; Biology; Bioinformatics; Genetics; Gene; Engineering; Epistemology","score_opus":0.08908880714549537,"score_gpt":0.45683574097179075,"score_spread":0.36774693382629536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3151926724","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012846438,0.9915937,0.0061962856,0.000067283094,0.00010537382,0.0005516024,0.000026832684,0.000007821823,0.00016642916],"genre_scores_gemma":[0.004145251,0.9921025,0.0024032395,0.0004881059,0.00048192544,0.000097491524,0.00015334102,0.0000691747,0.00005894457],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99822235,0.00020266433,0.0006705073,0.00052997883,0.00016242494,0.00021209256],"domain_scores_gemma":[0.99868,0.000055609285,0.0001560908,0.0008391354,0.00007727219,0.0001919017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004968445,0.00028116186,0.0006844478,0.00004182959,0.000104557854,0.000036527406,0.00037390736,0.0008101313,0.00002224814],"category_scores_gemma":[0.00008951794,0.00021274132,0.00028930444,0.00011055576,0.00019313714,4.2223613e-7,0.00027344163,0.00050739036,0.000004644376],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011675108,0.00004919076,0.00045163356,0.0017483699,0.00031986495,0.0000036398083,0.00008308394,0.00005936381,0.022032589,0.00006983607,0.010841404,0.96432936],"study_design_scores_gemma":[0.00014757211,0.00014095988,0.0003616522,0.00053698686,0.00020013326,0.000041819112,0.000016084436,0.000003472235,0.0016246117,0.000017301629,0.9965997,0.00030975655],"about_ca_topic_score_codex":0.0000016970735,"about_ca_topic_score_gemma":0.00000599855,"teacher_disagreement_score":0.98575824,"about_ca_system_score_codex":0.000009014419,"about_ca_system_score_gemma":0.0001547301,"threshold_uncertainty_score":0.8675339},"labels":[],"label_agreement":null},{"id":"W3152505723","doi":"10.1038/s41598-021-86753-7","title":"Nanopore long-read RNA-seq and absolute quantification delineate transcription dynamics in early embryo development of an insect pest","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"University of Thessaly; International Atomic Energy Agency; Canada Foundation for Innovation; Compute Canada; Genome Canada; European Social Fund; McGill University","keywords":"Biology; Transcriptome; Nanopore sequencing; Minion; Genome; RNA-Seq; Computational biology; Genetics; Gene; Transcription (linguistics); Zygote; De novo transcriptome assembly; Embryo; Gene expression; Embryogenesis","score_opus":0.01430939500013416,"score_gpt":0.2732952293458159,"score_spread":0.25898583434568173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3152505723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851423,0.0006102902,0.0131960455,0.00001828501,0.0008231145,0.00011156423,0.0000037806135,0.000008204269,0.00008641316],"genre_scores_gemma":[0.9953754,0.000027262318,0.0032219868,0.000004296727,0.000022050426,0.000008980443,0.0006223727,0.000012417614,0.0007052452],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986943,0.00002432102,0.00044170147,0.0005126409,0.00016425429,0.00016277218],"domain_scores_gemma":[0.99925846,0.0000023054947,0.0001047078,0.00040982294,0.00016020561,0.00006447173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005543095,0.00010499035,0.000118733406,0.0000818959,0.00007488956,0.0000620045,0.000057487305,0.00008867529,0.000006156492],"category_scores_gemma":[0.000041297255,0.00011265195,0.00003468061,0.00019441532,0.00006467361,0.000009936527,0.000032489912,0.0000515605,6.167474e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009563033,0.000058605947,0.004888065,0.000045031804,0.000010320136,0.00004927611,0.00032462509,0.00055319833,0.98443055,0.000010018315,0.000016554888,0.009604162],"study_design_scores_gemma":[0.00017001524,0.000039698472,0.08292557,0.000038668135,0.000011124761,0.00012900465,0.00017455041,0.0029608114,0.91247934,0.0000723652,0.0008261375,0.00017269544],"about_ca_topic_score_codex":0.000038151346,"about_ca_topic_score_gemma":0.0027060583,"teacher_disagreement_score":0.07803751,"about_ca_system_score_codex":0.000024494993,"about_ca_system_score_gemma":0.00016766593,"threshold_uncertainty_score":0.4593813},"labels":[],"label_agreement":null},{"id":"W3153565585","doi":"10.17863/cam.45194","title":"Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic","year":2017,"lang":"en","type":"article","venue":"UWA Profiles and Research Repository (UWA)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Alberta","funders":"University of Tasmania","keywords":"CRISPR; Genome editing; Somatic cell; Palindrome; Cas9; Biology; Genome; Computational biology; Medicine; Genetics; Gene","score_opus":0.05332405044405362,"score_gpt":0.38726800973652653,"score_spread":0.3339439592924729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3153565585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9642067,0.028909206,0.00004976233,0.00086850405,0.00020093021,0.0003784312,0.0000014607344,0.000013125468,0.0053718663],"genre_scores_gemma":[0.9764468,0.021188324,0.00016305488,0.00001847345,0.00033281295,0.00008394043,0.0000068071504,0.000027857612,0.0017319254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984677,0.00018471395,0.00024020209,0.00041565092,0.00027124496,0.00042050923],"domain_scores_gemma":[0.99885297,0.00009461152,0.000074166695,0.00077617046,0.00009282211,0.00010925029],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010578495,0.00015559296,0.00016528435,0.00007842126,0.0006705877,0.00017942475,0.0004752535,0.0001648636,0.000006893012],"category_scores_gemma":[0.0001820046,0.00011088822,0.00006462996,0.000046433324,0.00024472357,0.000009415433,0.00031946428,0.00034049162,0.000009275369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006305574,0.000083570965,0.0075817253,0.00020364767,0.000041997402,0.000032991764,0.0016985757,0.000014970715,0.9763126,0.000026814927,0.00044857376,0.013491501],"study_design_scores_gemma":[0.00061140966,0.00025673033,0.042570885,0.000085114334,0.000004246625,0.000014313424,0.0014247234,0.0007456167,0.9433914,0.00008870945,0.010626956,0.00017991113],"about_ca_topic_score_codex":0.00016344209,"about_ca_topic_score_gemma":0.000007400731,"teacher_disagreement_score":0.03498916,"about_ca_system_score_codex":0.000014419483,"about_ca_system_score_gemma":0.00007355358,"threshold_uncertainty_score":0.5157686},"labels":[],"label_agreement":null},{"id":"W3154416445","doi":"10.1089/hum.2020.301","title":"Intracerebroventricular Administration of AAV9-PHP.B SYN1-EmGFP Induces Widespread Transgene Expression in the Mouse and Monkey Central Nervous System","year":2021,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia; BC Children's Hospital","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Transgene; Woodchuck hepatitis virus; Central nervous system; Neuropil; Adeno-associated virus; Viral vector; Synapsin; Virology; Striatum; Molecular biology; Cell biology; Green fluorescent protein; Neuron; Neuroscience; Vector (molecular biology); Virus; Gene; Genetics; Recombinant DNA","score_opus":0.012760841365755055,"score_gpt":0.28301172691097165,"score_spread":0.2702508855452166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154416445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99200815,0.005968209,0.0016338871,0.000045330475,0.000053361313,0.00020340276,0.000011363699,0.000009638653,0.00006664015],"genre_scores_gemma":[0.99836576,0.0009833855,0.0003080016,0.000042666936,0.00012529035,0.000021713455,0.00009811551,0.00001801748,0.000037028305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906945,0.000102542246,0.00024691943,0.0002552555,0.00013271002,0.0001931327],"domain_scores_gemma":[0.99954224,0.000011149362,0.00005949192,0.00030192806,0.00003931952,0.00004589766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013623878,0.0001447361,0.0001541425,0.000032641325,0.00006033136,0.000028439175,0.00013617155,0.00011191705,0.000009291814],"category_scores_gemma":[0.000007973731,0.00011642207,0.00006282232,0.000082804254,0.000033206015,0.000004531812,0.000021317934,0.00007860292,2.990823e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056461486,0.000082216415,0.00040067924,0.00004415718,0.000025649333,0.000021658616,0.0004695324,0.0004715541,0.99618566,0.000040441326,0.00004488713,0.0021570923],"study_design_scores_gemma":[0.0006316707,0.00021869758,0.012326187,0.000029293471,0.0000098234905,0.0000755711,0.0004883957,0.00005179337,0.98567003,0.000014337157,0.00035487086,0.00012931446],"about_ca_topic_score_codex":0.000016457829,"about_ca_topic_score_gemma":0.000040664512,"teacher_disagreement_score":0.011925508,"about_ca_system_score_codex":0.0000097135835,"about_ca_system_score_gemma":0.000036050747,"threshold_uncertainty_score":0.4747554},"labels":[],"label_agreement":null},{"id":"W3154637159","doi":"10.1101/2021.04.08.438850","title":"The methyl phosphate capping enzyme Bin3 is a stable component of the fission yeast telomerase holoenzyme","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Institut Universitaire de France; Centre National de la Recherche Scientifique; Université de Perpignan Via Domitia; Agence Nationale de la Recherche","keywords":"Telomerase; Telomerase RNA component; Telomerase reverse transcriptase; Biology; RNA; Protein subunit; Telomere; Yeast; Schizosaccharomyces; Schizosaccharomyces pombe; Cell biology; Biochemistry; DNA; Saccharomyces cerevisiae; Gene","score_opus":0.008662665171959346,"score_gpt":0.23680029613350237,"score_spread":0.22813763096154302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154637159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97705936,0.01794826,0.0026598214,0.00034464066,0.0012526014,0.00050599006,0.00018183963,0.000039627786,0.000007871695],"genre_scores_gemma":[0.9964126,0.0018194446,0.0011010949,0.00019050846,0.00026352255,0.000086218366,0.0000014676205,0.000088291024,0.00003685494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99774593,0.0001455339,0.00051347073,0.00074193906,0.0003569504,0.0004961516],"domain_scores_gemma":[0.99733526,0.000029049406,0.00033389867,0.0017872405,0.0003559609,0.00015860294],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053685973,0.00044429032,0.00039666198,0.00005738137,0.0002660266,0.00014256577,0.00078739296,0.00038920977,0.000021847492],"category_scores_gemma":[0.00017009124,0.00033295923,0.00029785413,0.00030295347,0.00014336125,0.0000058322107,0.0012217609,0.00048654698,0.0000041821345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021991358,0.00005746107,0.0007312325,0.00017901916,0.0001938818,0.0000062777885,0.000020005622,0.0008551249,0.99697536,0.000020727224,0.0009325209,0.000006405545],"study_design_scores_gemma":[0.00028796936,0.00002768145,0.012383515,0.00027751175,0.000081244136,5.4421946e-8,0.000018672847,0.00046421573,0.96023005,4.1179763e-7,0.025844479,0.0003842164],"about_ca_topic_score_codex":0.000094018724,"about_ca_topic_score_gemma":0.0000075409293,"teacher_disagreement_score":0.036745325,"about_ca_system_score_codex":0.000060908384,"about_ca_system_score_gemma":0.00042654172,"threshold_uncertainty_score":0.99991226},"labels":[],"label_agreement":null},{"id":"W3155385010","doi":"10.1038/s41587-021-00891-x","title":"Genome-wide specificity of prime editors in plants","year":2021,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Retrotransposon; Biology; Genome; Primer (cosmetics); Genetics; RNA; Computational biology; Reverse transcriptase; Telomere; Murine leukemia virus; Virus; Gene; Transposable element","score_opus":0.003386455373979908,"score_gpt":0.2504060085970241,"score_spread":0.2470195532230442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3155385010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99014777,0.0062027527,0.001728753,0.00050750957,0.0008337145,0.00007242956,0.000019690322,0.000020868125,0.00046650122],"genre_scores_gemma":[0.9975016,0.0005655881,0.0012321728,0.000058795235,0.0004271186,0.0000028651687,0.00006510973,0.000012342384,0.0001343845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992664,0.000014687088,0.00016481019,0.0002891164,0.00007345737,0.00019155633],"domain_scores_gemma":[0.9995268,0.000011018233,0.000038132534,0.0003611777,0.00003753696,0.000025347363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007128573,0.00010465356,0.00015541498,0.00009286443,0.000011951752,0.0000027825251,0.00017215221,0.0010917968,0.000017360402],"category_scores_gemma":[0.00016760228,0.000109511835,0.000047653273,0.00016299287,0.00005790686,9.334145e-7,0.00013408763,0.00038197165,0.0000031461975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016845754,0.000040115672,0.0038292636,0.0000121361245,0.000017601793,0.000020986725,0.000007944887,0.00005384907,0.9944534,0.000076863194,0.0005678048,0.00090321025],"study_design_scores_gemma":[0.00020993374,0.000049964314,0.023094822,0.0000075977764,0.0000026794535,0.000019764737,0.000036172893,0.0000067213923,0.8709602,0.000051202875,0.10546449,0.000096446944],"about_ca_topic_score_codex":0.0000033928206,"about_ca_topic_score_gemma":0.000047599195,"teacher_disagreement_score":0.12349318,"about_ca_system_score_codex":0.000011215776,"about_ca_system_score_gemma":0.000049207647,"threshold_uncertainty_score":0.84209365},"labels":[],"label_agreement":null},{"id":"W3156657399","doi":"10.1101/2021.04.11.439384","title":"CRISPR Knock-in Designer: automatic oligonucleotide design software to introduce point mutations using CRISPR/Cas9","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Sunnybrook Health Science Centre; Children's Hospital of Eastern Ontario","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Biology; Point mutation; Genetics; Oligonucleotide; Gene; Context (archaeology); Computer science; Mutation","score_opus":0.015268198016820568,"score_gpt":0.2701409469980115,"score_spread":0.25487274898119094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156657399","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5322708,0.001548521,0.4645049,0.00009388822,0.0006624636,0.00073473,0.000049210164,0.00013402582,0.0000014952583],"genre_scores_gemma":[0.75254637,0.00011538678,0.24624872,0.00023718106,0.00044924105,0.00020340584,0.0000028114696,0.00019237988,0.000004512438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961212,0.00028334864,0.00082289596,0.0015537314,0.0003483082,0.0008704596],"domain_scores_gemma":[0.9970694,0.000057871715,0.0002339962,0.0017200974,0.00050069473,0.00041793677],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00073289324,0.00077366905,0.0007038684,0.00041960474,0.00016499976,0.00029486264,0.00064409134,0.0006326833,0.000047068104],"category_scores_gemma":[0.0010554302,0.0009547423,0.00023994342,0.0006422961,0.00007141417,0.000018626002,0.0008033055,0.00059331366,0.000027036283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020801826,0.00012216027,0.0010294568,0.00031951917,0.00014092712,0.00009418371,0.000040554303,0.080826625,0.91699326,0.00001073022,0.0003877787,0.000014007193],"study_design_scores_gemma":[0.00048166836,0.00010748919,0.014986984,0.0005216168,0.00015934439,4.2658476e-7,0.00003002405,0.0097530065,0.9722524,0.000001752126,0.0005087145,0.0011965331],"about_ca_topic_score_codex":0.00010279233,"about_ca_topic_score_gemma":0.000018509692,"teacher_disagreement_score":0.22027558,"about_ca_system_score_codex":0.0002711918,"about_ca_system_score_gemma":0.00092587015,"threshold_uncertainty_score":0.9992903},"labels":[],"label_agreement":null},{"id":"W3156696087","doi":"10.1016/j.xpro.2021.100451","title":"Protocol for RNA-seq library preparation starting from a rare muscle stem cell population or a limited number of mouse embryonic stem cells","year":2021,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre","funders":"H2020 European Research Council; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Horizon 2020 Framework Programme; Centro Nacional de Investigaciones Cardiovasculares; Universitat Pompeu Fabra; National Institutes of Health; Ministerio de Economía y Competitividad; Engineering Research Centers; Centre de Regulació Genòmica","keywords":"Biology; Embryonic stem cell; cDNA library; Complementary DNA; RNA extraction; Stem cell; Cell sorting; RNA; Population; Cell biology; Molecular biology; Cell; Computational biology; Genetics; Gene; Medicine","score_opus":0.025949220990867095,"score_gpt":0.3440196559121343,"score_spread":0.3180704349212672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156696087","genre_codex":"empirical","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5067632,0.000009750149,0.00510158,0.000024068853,0.000028253759,0.48764125,0.0002505997,0.000049061953,0.00013221358],"genre_scores_gemma":[0.06392041,0.000001082363,0.010771819,0.000055962628,0.00015971596,0.92102766,0.00031349336,0.0000698533,0.0036799982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864477,0.00008845177,0.00043972602,0.00042887055,0.00015199043,0.00024618141],"domain_scores_gemma":[0.9991078,0.00003053829,0.00021843622,0.00045164625,0.0001159421,0.00007566603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103738275,0.00019896637,0.00022710708,0.000026491318,0.00006190122,0.00005894743,0.00014019731,0.0001719024,0.00010670809],"category_scores_gemma":[0.000012208679,0.00018654566,0.00012214918,0.00012706056,0.000013540444,0.000021808892,0.000110194735,0.000075078744,0.000004325277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087664305,0.00015662286,0.0010217545,0.0007705304,0.00003417882,0.0000029879666,0.00016463938,0.0010127982,0.9920605,0.000008095601,0.0014889953,0.0024022844],"study_design_scores_gemma":[0.0019982457,0.00037572597,0.00025541655,0.00014243538,0.000012956293,7.746342e-7,0.00017396244,0.0013887669,0.9787304,0.000047781203,0.016646849,0.0002266842],"about_ca_topic_score_codex":0.000014039145,"about_ca_topic_score_gemma":0.000025781776,"teacher_disagreement_score":0.4428428,"about_ca_system_score_codex":0.000017069271,"about_ca_system_score_gemma":0.00017873381,"threshold_uncertainty_score":0.76071113},"labels":[],"label_agreement":null},{"id":"W3156742286","doi":"10.15173/m.v1i28.2619","title":"Hacking the brain: Gene therapy as a tool to combat epilepsy","year":2021,"lang":"en","type":"article","venue":"The Meducator","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Epilepsy; Hacker; Medicine; Psychiatry; Neuroscience; Psychology; Bioinformatics; Biology; Computer security; Computer science","score_opus":0.011188843487709658,"score_gpt":0.3110253490901139,"score_spread":0.29983650560240427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156742286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778174,0.004267843,0.0012118365,0.015400216,0.0005185946,0.00018180939,0.0000041965636,0.000011488354,0.0005865964],"genre_scores_gemma":[0.9876831,0.00025164156,0.00044331336,0.008419979,0.0006685505,0.00005393526,0.000017837037,0.00002503263,0.0024365976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992912,0.000057540194,0.0001126059,0.00021442876,0.00010733224,0.00021693189],"domain_scores_gemma":[0.9992025,0.000038980565,0.000019726816,0.0006274627,0.000048652833,0.00006270934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000221458,0.0001169602,0.00008835665,0.000011274404,0.00012619072,0.000042886913,0.00028587773,0.000047175472,0.00010771741],"category_scores_gemma":[0.00015889108,0.00007085144,0.00008089965,0.000111625064,0.000035205212,0.0000010168011,0.0001181384,0.00008482089,0.00005931787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020997082,0.000031077212,0.00023267076,0.0000034808734,0.0000551263,0.0000029871421,0.0007852123,0.00014168942,0.9720019,0.00017329057,0.015069238,0.011482349],"study_design_scores_gemma":[0.0001503123,0.0000520226,0.0033798986,0.0000048403776,0.000006410896,0.000050835304,0.00037082867,0.000008671521,0.6660211,0.00006248957,0.3297869,0.00010570746],"about_ca_topic_score_codex":0.000014969357,"about_ca_topic_score_gemma":0.000013120526,"teacher_disagreement_score":0.31471765,"about_ca_system_score_codex":0.0000080794325,"about_ca_system_score_gemma":0.00012723422,"threshold_uncertainty_score":0.28892377},"labels":[],"label_agreement":null},{"id":"W3157235751","doi":"10.21203/rs.3.rs-380297/v1","title":"Viral-eukaryotic gene exchange drives infection mode and cellular evolution","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Gordon and Betty Moore Foundation","keywords":"Virology; Gene; Biology; Genetics; Computational biology","score_opus":0.020943938685126815,"score_gpt":0.3642006278321687,"score_spread":0.3432566891470419,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3157235751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9282201,0.020064672,0.050658,0.00005920123,0.00025045476,0.0004240662,0.00003438668,0.000024505194,0.00026462108],"genre_scores_gemma":[0.9910625,0.0061535435,0.0006316338,0.0000075010125,0.0006267357,0.00011588184,0.0007702785,0.0000425517,0.0005893441],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99820465,0.00021211269,0.00017547865,0.00065030454,0.0003476678,0.00040976264],"domain_scores_gemma":[0.9989718,0.000016514918,0.000035119847,0.00056638947,0.00026790384,0.00014222928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039954172,0.00021250724,0.00019146258,0.00017885477,0.0001352216,0.00011069887,0.00013615181,0.00043840872,0.000026926016],"category_scores_gemma":[0.00013299551,0.00023395538,0.0001122164,0.0001186427,0.00009030054,0.000003947716,0.0010816419,0.0005442949,0.0000052717905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029422341,0.000078146615,0.008157708,0.0014206247,0.00009827955,0.000024688927,0.00022082309,0.008390406,0.97850895,0.00003553055,0.00052841334,0.0025070175],"study_design_scores_gemma":[0.0006108644,0.0004899675,0.0672948,0.00047767418,0.00005110084,0.000028964187,0.0002188583,0.0118139,0.9133127,0.00053653796,0.0044381614,0.00072648405],"about_ca_topic_score_codex":0.0004156594,"about_ca_topic_score_gemma":0.00015903659,"teacher_disagreement_score":0.065196246,"about_ca_system_score_codex":0.000078794685,"about_ca_system_score_gemma":0.00015712391,"threshold_uncertainty_score":0.9540423},"labels":[],"label_agreement":null},{"id":"W3157355255","doi":"10.1101/2021.05.04.442579","title":"The Mediator tail module cooperates with proneural factors to determine fate identity in Glioblastoma","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Stand Up To Cancer; Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Government of Canada; Ontario Institute for Cancer Research; Government of Ontario; American Association for Cancer Research","keywords":"Biology; Induced pluripotent stem cell; Reprogramming; Stem cell; Transcription factor; Cellular differentiation; Embryonic stem cell; Mediator; Cell biology; Neural stem cell; Cancer research; Gene; Genetics","score_opus":0.00761637485064483,"score_gpt":0.241948003699005,"score_spread":0.23433162884836015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3157355255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946181,0.0015668743,0.0024035703,0.00010006656,0.000592821,0.0005974462,0.00006533021,0.000054528075,0.0000012521324],"genre_scores_gemma":[0.998147,0.00027298994,0.0009102533,0.00006593756,0.00026534504,0.00022248701,0.0000013010854,0.00010424976,0.000010451685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978208,0.00008152181,0.00038117947,0.00086876826,0.00028925514,0.0005584842],"domain_scores_gemma":[0.9982585,0.000023275066,0.00012155539,0.0010287013,0.00032344493,0.0002445557],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028050318,0.0004893666,0.00036948468,0.00010751964,0.000132913,0.00031807774,0.00057844585,0.0003216774,0.0000074851405],"category_scores_gemma":[0.00023682725,0.0003954137,0.00009503311,0.00040439874,0.00008140355,0.0000146560915,0.00067850115,0.00040281058,0.000006082094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066541405,0.000052606607,0.017740967,0.00010807398,0.00008799442,0.000044320073,0.000018984796,0.0025483617,0.97926635,0.000008141082,0.000054915978,0.0000027323836],"study_design_scores_gemma":[0.0003298495,0.00016703883,0.07018972,0.00012998353,0.00003139852,5.8599507e-8,0.000021631908,0.0003702943,0.9271812,1.12314375e-7,0.001032004,0.0005467035],"about_ca_topic_score_codex":0.000046090736,"about_ca_topic_score_gemma":0.00048850797,"teacher_disagreement_score":0.052448757,"about_ca_system_score_codex":0.000073848074,"about_ca_system_score_gemma":0.00033429617,"threshold_uncertainty_score":0.9998498},"labels":[],"label_agreement":null},{"id":"W3157778980","doi":"10.1242/jcs.254409","title":"CRISPR-Cas tools to study gene function in cytokinesis","year":2021,"lang":"en","type":"review","venue":"Journal of Cell Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Biology; CRISPR; Cytokinesis; Function (biology); Computational biology; Gene; Genetics; Cell; Cell division","score_opus":0.030355759885278846,"score_gpt":0.37555822892861995,"score_spread":0.3452024690433411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3157778980","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01312707,0.9789952,0.006877247,0.000008411989,0.0006051094,0.00024182472,0.0000027854828,0.0000015245225,0.00014081971],"genre_scores_gemma":[0.020550892,0.9775939,0.0012951161,0.000031240976,0.00036979635,0.000008651056,0.0000030149931,0.000018650007,0.00012875076],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99851996,0.000058020356,0.0005480205,0.00030230568,0.00034480778,0.00022691363],"domain_scores_gemma":[0.9991464,0.000018102935,0.00021838087,0.0002860243,0.00018846801,0.0001426198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000956471,0.00018105248,0.0005563586,0.00026439063,0.000044854918,0.000081187114,0.00046858,0.000091654896,0.000015356067],"category_scores_gemma":[0.00018569207,0.00014630529,0.0001998646,0.0007251934,0.000027398457,0.00000771351,0.00017314173,0.00018133344,0.0000046171504],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015068632,0.00030275673,0.00007356299,0.0005392587,0.00005175539,0.00012483727,0.000119391516,0.00069098826,0.10384049,0.0000011787105,0.00035512593,0.89388555],"study_design_scores_gemma":[0.0003422867,0.0010702878,0.00068736274,0.0009164251,0.0002766961,0.00025520014,0.00019596794,0.000003596388,0.054201677,0.0000017966728,0.9416658,0.0003828841],"about_ca_topic_score_codex":0.0000022358192,"about_ca_topic_score_gemma":0.0000061843543,"teacher_disagreement_score":0.9413107,"about_ca_system_score_codex":0.00005604651,"about_ca_system_score_gemma":0.00045633584,"threshold_uncertainty_score":0.5966157},"labels":[],"label_agreement":null},{"id":"W3158372074","doi":"10.15173/sciential.v1i4.2423","title":"Bioethical Analysis of Gene Editing","year":2020,"lang":"en","type":"article","venue":"Sciential - McMaster Undergraduate Science Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Eugenics; Bioethics; Genome editing; Biology; Ideology; Environmental ethics; Altruism (biology); Genetics; Gene; Sociology; Political science; Evolutionary biology; CRISPR; Politics; Law; Philosophy","score_opus":0.018639020029885697,"score_gpt":0.3158241397960391,"score_spread":0.2971851197661534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158372074","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.715682,0.00021776842,0.27888048,0.0033231971,0.0008240908,0.00007171382,0.000012993385,0.000011002639,0.0009767503],"genre_scores_gemma":[0.9928275,0.000031129795,0.0062523657,0.0002903386,0.00050673087,5.65017e-7,0.0000057893703,0.000008056389,0.00007755092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981576,0.000028409102,0.00034464715,0.00039999068,0.0006823712,0.00038693813],"domain_scores_gemma":[0.99906063,0.000006011168,0.00015190624,0.00016902933,0.00024683253,0.00036558407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008490201,0.0001236371,0.000190444,0.00028928695,0.0002733673,0.00016743515,0.00057281164,0.000058090627,0.00006904488],"category_scores_gemma":[0.00020800058,0.00010846641,0.00021042704,0.002014932,0.00058538886,0.000020710404,0.00018296577,0.00018374539,0.0000047079857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001604408,0.000015787975,0.0014387288,0.0000046606883,0.00010041346,0.0000027038743,0.00016813505,0.0120383315,0.9840881,0.000051683983,0.0002392048,0.0018361793],"study_design_scores_gemma":[0.0005264154,0.000372255,0.0047035925,0.000011576376,0.0003117601,0.000051228184,0.0003570882,0.0362521,0.9537918,0.00011018495,0.0032511314,0.00026084945],"about_ca_topic_score_codex":0.0000034198993,"about_ca_topic_score_gemma":0.0000049989812,"teacher_disagreement_score":0.27714545,"about_ca_system_score_codex":0.000014036151,"about_ca_system_score_gemma":0.00018113723,"threshold_uncertainty_score":0.4423132},"labels":[],"label_agreement":null},{"id":"W3159676041","doi":"10.17504/protocols.io.4vdgw26","title":"CRISPR-Cas9 Genome Editing in Human Primary T Cells v1","year":2019,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stemcell Technologies","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Electroporation; Genome; Biology; Human genome; Gene; Guide RNA; Genetics","score_opus":0.008355908595171838,"score_gpt":0.2848318457803278,"score_spread":0.27647593718515595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159676041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92518324,0.002775707,0.031943396,0.00008242931,0.0015924168,0.00071009644,0.00006125644,0.00005154368,0.037599906],"genre_scores_gemma":[0.991546,0.00025410985,0.0020980916,0.0002388612,0.0011380324,0.00003588153,0.00068791484,0.00006604661,0.003935101],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839836,0.000029952844,0.00036992077,0.0006785012,0.00014514198,0.0003781132],"domain_scores_gemma":[0.99906236,0.000007378621,0.00008735134,0.000718493,0.000046350524,0.0000780905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020766906,0.00032110006,0.00032132078,0.0001060095,0.000030873267,0.000044568667,0.00037666323,0.00049990334,0.000091523994],"category_scores_gemma":[0.0000133631165,0.0003464111,0.00015797476,0.00004628134,0.00002661742,0.0000013127571,0.0010264682,0.00042596195,0.000034852237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000058876417,0.000036771315,0.00074194267,0.00030418969,0.00003754623,0.000007685261,0.0000520709,0.02546817,0.9713109,0.000013621043,0.0017353423,0.00028583317],"study_design_scores_gemma":[0.000801032,0.00015160278,0.012231746,0.00013644296,0.000042164054,0.0000108487575,0.00012773678,0.0005804403,0.9393897,0.00012347646,0.04526475,0.0011400711],"about_ca_topic_score_codex":0.000076156495,"about_ca_topic_score_gemma":0.000050956616,"teacher_disagreement_score":0.06636271,"about_ca_system_score_codex":0.00004434991,"about_ca_system_score_gemma":0.00008091005,"threshold_uncertainty_score":0.9998988},"labels":[],"label_agreement":null},{"id":"W3159871407","doi":"10.15173/sciential.v1i1.1910","title":"Evading Evasion","year":2018,"lang":"en","type":"article","venue":"Sciential - McMaster Undergraduate Science Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Evasion (ethics); Computational biology; Genome editing; Computer science; Biology; Gene; Genetics; Immune system","score_opus":0.01188043831359732,"score_gpt":0.32043843758708335,"score_spread":0.30855799927348604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159871407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87851626,0.00019189072,0.10792754,0.00071199157,0.003729289,0.0001017646,0.0000017299087,0.000018271165,0.008801279],"genre_scores_gemma":[0.992396,0.00004017697,0.0041823424,0.00016025582,0.0013302594,0.0000010402517,0.000001398834,0.000013034682,0.0018754968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99810594,0.000022820197,0.0002307894,0.00043235227,0.0006329882,0.0005750882],"domain_scores_gemma":[0.99904287,0.0000031783702,0.00008623168,0.0002495672,0.0003169125,0.0003012252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012052931,0.0001416244,0.00009246906,0.00021820191,0.0009122578,0.00042141325,0.00060760963,0.000050496466,0.00012442295],"category_scores_gemma":[0.000108517976,0.00012021113,0.00008514678,0.00059414696,0.00084244314,0.000036613907,0.00025846262,0.00013675152,0.000072284274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017516348,0.000016059763,0.00047769866,0.0000022076254,0.000006599167,0.00000206865,0.00007603805,0.0001787731,0.9872223,0.0000741446,0.0015745122,0.010352085],"study_design_scores_gemma":[0.0006993711,0.0006831869,0.0032642724,0.000041325493,0.000019243846,0.00056608947,0.00017331271,0.0035287219,0.9400947,0.0012211442,0.04934777,0.00036084352],"about_ca_topic_score_codex":0.0000024819426,"about_ca_topic_score_gemma":0.000008658758,"teacher_disagreement_score":0.11387975,"about_ca_system_score_codex":0.000037671765,"about_ca_system_score_gemma":0.0002392995,"threshold_uncertainty_score":0.7016442},"labels":[],"label_agreement":null},{"id":"W3160270231","doi":"","title":"Implications of Biological Information Digitization: Access and Benefit Sharing of Plant Genetic Resources","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Saskatchewan","funders":"","keywords":"Digitization; Genetic resources; Intellectual property; Corporate governance; Knowledge management; Business; Value (mathematics); Computer science; Data science; Biotechnology; Telecommunications; Biology","score_opus":0.011236256329815373,"score_gpt":0.2680046756071259,"score_spread":0.2567684192773105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160270231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.941097,0.0017687052,0.056647424,0.00021684391,0.000012465748,0.000060600585,0.0000191534,0.0000040283653,0.00017375629],"genre_scores_gemma":[0.99552816,0.0041626208,0.00014308508,0.00004879899,0.000070702896,0.0000020832717,0.000032799373,0.0000042006054,0.00000754157],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99938345,0.000003653878,0.00021630127,0.000080387654,0.000051071638,0.00026513558],"domain_scores_gemma":[0.9997255,0.0000049956784,0.000101962534,0.00007128289,0.000052686173,0.00004354706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000890287,0.000060124235,0.000083725536,0.000028590413,0.000033605997,0.00001902656,0.00016072801,0.000048700236,0.0000030786757],"category_scores_gemma":[0.000029446712,0.000053199226,0.000031697677,0.00006848308,0.000025228544,0.000009859152,0.000080411744,0.00012086276,2.2716532e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035309148,0.00008277855,0.27929762,0.00020000161,0.00049224496,6.785136e-7,0.0012081185,0.02166821,0.55210274,0.05707046,0.00011778622,0.08740627],"study_design_scores_gemma":[0.003305895,0.0040432597,0.56571734,0.000108181775,0.00016526452,0.00092349376,0.0020168116,0.003991859,0.2877312,0.109471254,0.021537922,0.0009875308],"about_ca_topic_score_codex":0.0000039899787,"about_ca_topic_score_gemma":0.000011315906,"teacher_disagreement_score":0.28641972,"about_ca_system_score_codex":0.0000104790815,"about_ca_system_score_gemma":0.00005605469,"threshold_uncertainty_score":0.21694015},"labels":[],"label_agreement":null},{"id":"W3161239394","doi":"10.1128/msphere.00185-21","title":"Primed CRISPR-Cas Adaptation and Impaired Phage Adsorption in Streptococcus mutans","year":2021,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"CRISPR; Bacteriophage; Biology; Virulence; Microbiology; Plasmid; Phagemid; Genome; Virology; Genetics; Gene; Escherichia coli","score_opus":0.01041386739591643,"score_gpt":0.2807219920823678,"score_spread":0.2703081246864514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161239394","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817776,0.0022770138,0.015161866,0.00006261593,0.00007280032,0.00011658975,0.0000068775653,0.000012161471,0.00051245594],"genre_scores_gemma":[0.99811924,0.00017111615,0.0010678851,0.00004389678,0.0000713035,0.000018419154,0.000085515494,0.000013118707,0.00040950935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944687,0.000024974162,0.000117995245,0.00022034618,0.000055903765,0.00013389389],"domain_scores_gemma":[0.99974,0.0000053850595,0.000020110323,0.00015073351,0.000040489223,0.00004324927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005217217,0.00008821733,0.00007986497,0.000012294932,0.000015403653,0.000017267452,0.00003528623,0.00008661439,0.00005943116],"category_scores_gemma":[0.000044106768,0.0000967621,0.000025758769,0.00008604353,0.000013671202,0.0000029666032,0.000036425245,0.00005255815,0.000003724892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017524464,0.000033886965,0.006660475,0.000027933556,0.000014457541,0.000016654434,0.00023371934,0.001394906,0.9752648,0.00001709081,0.000240567,0.016078023],"study_design_scores_gemma":[0.00085285836,0.00009203628,0.06313839,0.000023789396,0.000012962755,0.000021740088,0.00086798484,0.0031544124,0.9270379,0.000047678695,0.004561463,0.00018882359],"about_ca_topic_score_codex":0.000025355706,"about_ca_topic_score_gemma":0.00065177376,"teacher_disagreement_score":0.056477908,"about_ca_system_score_codex":0.0000110652145,"about_ca_system_score_gemma":0.0000428578,"threshold_uncertainty_score":0.3945844},"labels":[],"label_agreement":null},{"id":"W3161425918","doi":"10.1038/s41586-021-03534-y","title":"In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates","year":2021,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":768,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"","keywords":"CRISPR; PCSK9; Gene knockdown; Genome editing; In vivo; Biology; Genetic enhancement; Cholesterol; Gene; Cancer research; Computational biology; Bioinformatics; Genetics; LDL receptor; Lipoprotein; Endocrinology","score_opus":0.0031046539545461103,"score_gpt":0.27793038894596334,"score_spread":0.2748257349914172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161425918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955169,0.0026245224,0.0001714673,0.00039572976,0.0002678977,0.00005874891,0.000015633323,0.000004060249,0.0009450375],"genre_scores_gemma":[0.9985836,0.000094578776,0.0005905775,0.00038325472,0.00013950754,0.000004614183,0.000021631164,0.000012094969,0.00017011235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993978,0.00001697558,0.00015147553,0.00019800707,0.00008015305,0.00015558019],"domain_scores_gemma":[0.9997169,0.0000087530925,0.000027494965,0.00017356599,0.000045038727,0.000028288094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008962115,0.000087962726,0.00011172458,0.00004634414,0.0000082693,0.000007192422,0.00008101676,0.00046352553,0.000032560867],"category_scores_gemma":[0.00013434538,0.00009312743,0.000040771116,0.00013061729,0.000013662934,0.0000030621175,0.000051866587,0.0004170674,7.438484e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001153144,0.00003577938,0.009006354,0.00007015016,0.000006641533,0.000027706426,0.00005908984,0.00079334335,0.98777497,0.000016311868,0.0019818032,0.00021630374],"study_design_scores_gemma":[0.0004429433,0.000022988692,0.009230817,0.00004839941,0.0000034274372,0.000012155199,0.00015968757,0.00010085265,0.9835567,0.000013403624,0.006318621,0.00008999638],"about_ca_topic_score_codex":0.000010612953,"about_ca_topic_score_gemma":0.00015325048,"teacher_disagreement_score":0.0043368177,"about_ca_system_score_codex":0.0000097563625,"about_ca_system_score_gemma":0.000033372617,"threshold_uncertainty_score":0.37976265},"labels":[],"label_agreement":null},{"id":"W3161644370","doi":"10.3390/genes12050723","title":"New Insights into the Therapeutic Applications of CRISPR/Cas9 Genome Editing in Breast Cancer","year":2021,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Terry Fox Foundation","keywords":"CRISPR; Genome editing; Breast cancer; Computational biology; Cas9; Genome; Biology; Cancer; Genetics; Gene","score_opus":0.01573348700480573,"score_gpt":0.34391162743474585,"score_spread":0.3281781404299401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161644370","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000042544365,0.9908707,0.008466824,0.00005728159,0.00014734043,0.00032913632,0.00002039486,0.000004873294,0.00006091591],"genre_scores_gemma":[0.000550929,0.9974141,0.00027053646,0.000035406345,0.0011169796,0.0002394465,0.00013193455,0.000036767007,0.00020390125],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99905956,0.00005002101,0.00032706984,0.00031002096,0.00008991609,0.00016343381],"domain_scores_gemma":[0.99932116,0.00001748843,0.00011650976,0.00044637432,0.000054299027,0.000044166045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071514274,0.00021642672,0.000450513,0.000049925024,0.00004203085,0.000015667083,0.000303554,0.0001874902,0.000031352676],"category_scores_gemma":[0.0000041844987,0.0001568878,0.0001990829,0.0002503861,0.000029177238,0.0000012273122,0.00013232304,0.00012299525,0.0000029725559],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[7.308411e-7,0.000010633782,0.000014221032,0.0011007225,0.000107194006,7.907427e-7,0.000103029255,0.00012689101,0.003121676,0.000028479482,0.00009973892,0.99528587],"study_design_scores_gemma":[0.000057819474,0.0000075659336,0.000051890907,0.00047292328,0.0001407104,0.000016035912,0.00006606668,0.0000036488389,0.0012231575,0.000015287522,0.9977796,0.00016527396],"about_ca_topic_score_codex":0.00015224086,"about_ca_topic_score_gemma":0.00023993234,"teacher_disagreement_score":0.9976799,"about_ca_system_score_codex":0.000020421287,"about_ca_system_score_gemma":0.0002871542,"threshold_uncertainty_score":0.6397699},"labels":[],"label_agreement":null},{"id":"W3162093786","doi":"10.1111/bioe.12882","title":"Vulnerable groups and the hollow promise of benefit from human gene editing","year":2021,"lang":"en","type":"article","venue":"Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"NOSM University; Lakehead University","funders":"","keywords":"Human enhancement; Mainstream; Indigenous; Genome editing; Environmental ethics; Sociology; Point (geometry); Public relations; Internet privacy; Political science; Law; Computer science; Biology; CRISPR; Genetics; Gene; Ecology","score_opus":0.01919382354436059,"score_gpt":0.31366769580536474,"score_spread":0.29447387226100413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3162093786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914111,0.005305586,0.002056801,0.0005154834,0.00014972973,0.00007533728,0.00003073091,0.0000064909477,0.00044877033],"genre_scores_gemma":[0.99668366,0.00044389578,0.0019534219,0.00012552345,0.00039047236,0.0000074839027,0.000093711744,0.0000125836605,0.0002892735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994216,0.000041201674,0.00014609634,0.00018849762,0.00009030345,0.00011233214],"domain_scores_gemma":[0.99955213,0.000038712595,0.000044061107,0.0002535891,0.0000775591,0.00003396724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002886105,0.000083668834,0.00011540759,0.0000088926745,0.00010547332,0.000019337986,0.00008544414,0.00013407951,0.000012000313],"category_scores_gemma":[0.00014635206,0.00006709419,0.000051522376,0.000043350577,0.00017659256,0.0000012721105,0.000115983305,0.00015137476,5.755647e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001979454,0.000016132908,0.0007117156,0.00002525,0.00004943692,0.0000032823868,0.00025831335,0.00013434171,0.9963765,0.0016197177,0.0001259467,0.0006595308],"study_design_scores_gemma":[0.0009041245,0.00003494753,0.0015016693,0.00001861088,0.000030424913,0.000008583042,0.00030400662,0.00015401267,0.99368995,0.00094627775,0.0023105303,0.00009684389],"about_ca_topic_score_codex":0.00011348202,"about_ca_topic_score_gemma":0.00015323238,"teacher_disagreement_score":0.0052725635,"about_ca_system_score_codex":0.0000024968033,"about_ca_system_score_gemma":0.000025821786,"threshold_uncertainty_score":0.27360216},"labels":[],"label_agreement":null},{"id":"W3162439263","doi":"10.1101/2021.05.14.444239","title":"EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Epigenetics; Epigenome; CRISPR; Biology; Triple-negative breast cancer; Chromatin; Computational biology; Cancer; Subgenomic mRNA; Cancer research; Epigenetic therapy; Genetics; Gene; Breast cancer; DNA methylation; Gene expression","score_opus":0.020303084751448368,"score_gpt":0.28963741527672515,"score_spread":0.2693343305252768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3162439263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8270598,0.010727097,0.15924263,0.0001885761,0.0013871714,0.0008475987,0.0003591345,0.00018255747,0.000005460841],"genre_scores_gemma":[0.9675538,0.00071548834,0.029260825,0.00030498503,0.0011368657,0.00072995946,0.000010322187,0.0002743967,0.000013361557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956101,0.0001449377,0.0008655703,0.0018205894,0.0005508904,0.0010078885],"domain_scores_gemma":[0.9962982,0.000056592657,0.00029573936,0.0021831316,0.0006232322,0.0005431273],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005870352,0.00094542396,0.00082149275,0.00030950847,0.00026121794,0.00047835847,0.0008771173,0.00081739575,0.00014420111],"category_scores_gemma":[0.00027155265,0.0011258995,0.00040581304,0.00048929226,0.00012461623,0.000015171177,0.0008617932,0.0007119372,0.00002499305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005317652,0.000090669746,0.0017561137,0.00052151893,0.00020919934,0.00004245439,0.00002842945,0.02046759,0.9759925,0.000011321976,0.00078714127,0.000039906638],"study_design_scores_gemma":[0.0006908757,0.000111358524,0.037222803,0.0006653389,0.00010243372,6.2489676e-8,0.000024439474,0.0008899858,0.94814205,5.69597e-7,0.010840067,0.0013100185],"about_ca_topic_score_codex":0.00018100772,"about_ca_topic_score_gemma":0.000050384082,"teacher_disagreement_score":0.14049402,"about_ca_system_score_codex":0.00018835042,"about_ca_system_score_gemma":0.0007588758,"threshold_uncertainty_score":0.9991191},"labels":[],"label_agreement":null},{"id":"W3163096316","doi":"10.1101/2021.05.11.443710","title":"Saturation variant interpretation using CRISPR prime editing","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; University of Pennsylvania","keywords":"CRISPR; Genome editing; Computational biology; Gene; Biology; Genome; Genetics; Computer science","score_opus":0.00872059272146654,"score_gpt":0.25631303119085125,"score_spread":0.2475924384693847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163096316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68092614,0.0016696518,0.31516972,0.000044906425,0.0017597278,0.00030218766,0.000041180836,0.00007887975,0.0000076083506],"genre_scores_gemma":[0.975666,0.00016225674,0.022279287,0.00012393572,0.001594556,0.000049269114,0.0000063207667,0.0001152051,0.00000319173],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978499,0.000104286046,0.00047074398,0.0009163155,0.00024959963,0.00040915463],"domain_scores_gemma":[0.9982079,0.000012969347,0.00027530367,0.0009114479,0.0004385165,0.00015384829],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033949193,0.00043724992,0.00034463187,0.00012425793,0.000121058554,0.00026769104,0.0002938215,0.0005999511,0.000017711953],"category_scores_gemma":[0.00028890691,0.0005385062,0.0001788365,0.00018560239,0.000044110693,0.000014576624,0.0004966887,0.00045141458,0.0000051355046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016714948,0.00003852965,0.0005827246,0.00016809806,0.00012912323,0.000026866894,0.000016309992,0.0044612633,0.99446523,0.000015601783,0.00007293183,0.0000066218213],"study_design_scores_gemma":[0.00025398025,0.00004187258,0.00937997,0.00034383513,0.00012283855,1.8130955e-7,0.0000142060235,0.017112177,0.9713396,4.362235e-7,0.0007660179,0.0006249292],"about_ca_topic_score_codex":0.00003596916,"about_ca_topic_score_gemma":0.0000047367857,"teacher_disagreement_score":0.29473984,"about_ca_system_score_codex":0.00011250466,"about_ca_system_score_gemma":0.00040762094,"threshold_uncertainty_score":0.9997066},"labels":[],"label_agreement":null},{"id":"W3163368167","doi":"10.1007/s11248-021-00257-8","title":"Regulatory approaches for genome edited agricultural plants in select countries and jurisdictions around the world","year":2021,"lang":"en","type":"review","venue":"Transgenic Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":174,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Commercialization; Agriculture; Biology; Genome; Biotechnology; Selection (genetic algorithm); Gene; Business; Genetics; Marketing; Ecology","score_opus":0.10312436820709757,"score_gpt":0.408771788428838,"score_spread":0.3056474202217404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163368167","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021082086,0.99598134,0.00021775073,0.00008574519,0.00009123956,0.0011093633,0.000117801654,0.000007686561,0.00028086215],"genre_scores_gemma":[0.0030570808,0.99249625,0.00006571063,0.000006659872,0.0006446135,0.00054594077,0.00073479256,0.00003749587,0.0024114521],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982836,0.0002153556,0.00031490126,0.00047929698,0.00024060663,0.00046621772],"domain_scores_gemma":[0.9992906,0.00018208519,0.000031445765,0.000347401,0.00007427967,0.000074203075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084479834,0.0002408834,0.000490106,0.00016792824,0.00018637357,0.00008068411,0.00028109315,0.00024853766,0.000007662103],"category_scores_gemma":[0.000027142465,0.00016063872,0.00020770305,0.00038148995,0.00015705726,0.000002947847,0.0000636103,0.00046183006,0.0000018533833],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037963333,0.0006923938,0.00016271719,0.06877479,0.006040965,0.00004720057,0.004119726,0.0014283283,0.010185196,0.004309829,0.031060757,0.87279844],"study_design_scores_gemma":[0.00020609642,0.000058968897,0.00019155443,0.00049088435,0.00007921145,0.00003205715,0.000117212,0.000012793772,0.00029534526,0.000011217875,0.99830014,0.00020453906],"about_ca_topic_score_codex":0.0000073852407,"about_ca_topic_score_gemma":0.0003463537,"teacher_disagreement_score":0.9672394,"about_ca_system_score_codex":0.000044173546,"about_ca_system_score_gemma":0.00026825332,"threshold_uncertainty_score":0.6550657},"labels":[],"label_agreement":null},{"id":"W3163681195","doi":"10.1038/s41587-021-00933-4","title":"In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels","year":2021,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":377,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"PCSK9; Clearance; In vivo; Point mutation; Biology; Messenger RNA; Lipoprotein; Cholesterol; RNA; LDL receptor; Mutation; Molecular biology; Immunology; Medicine; Gene; Endocrinology; Genetics","score_opus":0.005635255797327141,"score_gpt":0.2937176011872165,"score_spread":0.28808234538988936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163681195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991546,0.0052678245,0.0003684526,0.0021871596,0.0002965178,0.00008055371,0.000026422762,0.00001810069,0.0002090031],"genre_scores_gemma":[0.9971212,0.00022708606,0.0020742754,0.00019635244,0.00017132988,0.000008749995,0.000016775968,0.000015805295,0.000168402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990777,0.000026111386,0.00023992594,0.00034931998,0.000074816395,0.00023216291],"domain_scores_gemma":[0.999578,0.00001094236,0.0000526367,0.00028985966,0.000043981385,0.000024574838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107596825,0.00013113001,0.00019617807,0.00017245962,0.000011041877,0.000004960558,0.00017960828,0.0011113272,0.00003351772],"category_scores_gemma":[0.0002528051,0.00014001477,0.00004539989,0.0002932356,0.00006356797,0.000003398756,0.00014597733,0.000506976,9.190546e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010627694,0.00003876612,0.0009595227,0.000027640184,0.000010541795,0.000039671053,0.000023209772,0.00007506385,0.9958354,0.00013422746,0.00038534385,0.00245999],"study_design_scores_gemma":[0.0004524545,0.000064514075,0.0021334982,0.000049865135,0.000004009758,0.000054318083,0.00011072308,0.00004746919,0.98500246,0.000065683314,0.011894635,0.00012038774],"about_ca_topic_score_codex":0.000012836819,"about_ca_topic_score_gemma":0.0002117231,"teacher_disagreement_score":0.011509291,"about_ca_system_score_codex":0.000013159548,"about_ca_system_score_gemma":0.000042975436,"threshold_uncertainty_score":0.85715735},"labels":[],"label_agreement":null},{"id":"W3163807883","doi":"10.1016/b978-0-444-64046-8.00231-7","title":"Recent Advances in Genomics-Based Animal Biotechnology: State of the Art of Selective Breeding and Embryo Genomics","year":2019,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Genomics; Biology; Genome; Functional genomics; Genetics; Computational biology; Epigenomics; Gene; DNA methylation; Gene expression","score_opus":0.005600779925425133,"score_gpt":0.23781166809358334,"score_spread":0.2322108881681582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163807883","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3688393,0.0990952,0.0003876244,0.00020942366,0.00064018863,0.0022797328,0.0003705556,0.000026881004,0.5281511],"genre_scores_gemma":[0.62139046,0.06986903,0.0028785518,0.00027371309,0.00027667743,0.00004261717,0.00010657283,0.00032841726,0.30483395],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999102,0.000010982034,0.00032527643,0.0003140684,0.00008134991,0.0001663322],"domain_scores_gemma":[0.9993539,0.0000125085835,0.00021787027,0.000326596,0.00006358584,0.00002558291],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012744786,0.00022037838,0.00032967151,0.00009106492,0.000018340937,0.0000042786914,0.0001919009,0.00026086302,0.0000033291362],"category_scores_gemma":[0.000015639354,0.00019508039,0.0000910824,0.000016966269,0.00016206219,0.0000013129894,0.00016089517,0.00021887076,9.997069e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007847545,0.0000060329803,0.00007034537,0.00012205911,0.000051930772,6.8381115e-7,0.00004780539,0.00042310165,0.4667746,0.000086822234,0.000009606911,0.5323285],"study_design_scores_gemma":[0.00033964257,0.0002595259,0.0001987701,0.00013243467,0.00003246124,0.0000050454446,0.000009252253,0.00008052428,0.41978458,0.00025035877,0.57869846,0.0002089529],"about_ca_topic_score_codex":2.6641084e-7,"about_ca_topic_score_gemma":0.000063196596,"teacher_disagreement_score":0.57868886,"about_ca_system_score_codex":0.000038583774,"about_ca_system_score_gemma":0.00016765023,"threshold_uncertainty_score":0.7955147},"labels":[],"label_agreement":null},{"id":"W3163881816","doi":"10.1002/leg3.96","title":"CRISPR/Cas9 gene editing in legume crops: Opportunities and challenges","year":2021,"lang":"en","type":"article","venue":"Legume Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Ministry of Agriculture and Forestry; Agriculture Food and Rural Development; Agriculture and Agri-Food Canada; Saskatchewan Research Council (Canada); University of Saskatchewan; University of Calgary; National Research Council Canada","funders":"Society of Pediatric Psychology","keywords":"Genome editing; Medicago truncatula; CRISPR; Biotechnology; Biology; Cas9; Food security; Legume; Gene; Agriculture; Genetics; Agronomy; Ecology; Symbiosis","score_opus":0.03627816345568864,"score_gpt":0.3051772843208067,"score_spread":0.2688991208651181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163881816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975867,0.016430205,0.0010814763,0.0017816927,0.00037391746,0.00006105442,0.0000064183937,0.000015379253,0.0043828636],"genre_scores_gemma":[0.99245584,0.004938847,0.0017338424,0.00016237656,0.00022747494,0.0000071514373,0.000008868936,0.000010076463,0.00045554826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989755,0.000018709536,0.00013579614,0.00040429976,0.00015960692,0.0003060663],"domain_scores_gemma":[0.9995322,0.000009034559,0.000024676021,0.00025531088,0.000078597084,0.00010014709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029416758,0.000107403386,0.00010087377,0.0000653931,0.000092853894,0.000061910934,0.00016522213,0.000057618225,0.000017090684],"category_scores_gemma":[0.00012476748,0.00011292798,0.000023185003,0.0001427265,0.00022767285,0.000012847741,0.00021637879,0.000069552545,0.0000033936274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000030310816,0.000019681216,0.0008387951,0.000039333045,0.0000044716708,0.000056288765,0.00030209552,0.00013228119,0.98554295,0.00060411985,0.00011229183,0.01234466],"study_design_scores_gemma":[0.00023942426,0.000060075912,0.010079793,0.000030792693,0.0000045017086,0.00013367808,0.0018593351,0.00038093215,0.9482453,0.00006663185,0.038679224,0.0002203506],"about_ca_topic_score_codex":0.000016019476,"about_ca_topic_score_gemma":0.00008940985,"teacher_disagreement_score":0.038566932,"about_ca_system_score_codex":0.000010768054,"about_ca_system_score_gemma":0.00012261541,"threshold_uncertainty_score":0.46050695},"labels":[],"label_agreement":null},{"id":"W3164375754","doi":"10.1186/s13213-021-01624-w","title":"The effect of crop species on DNase-producing bacteria in two soils","year":2021,"lang":"en","type":"article","venue":"Annals of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Stenotrophomonas; Crop; 16S ribosomal RNA; Microbacterium; Bacteria; Botany; Stenotrophomonas maltophilia; Flavobacterium; Brevibacterium; Serratia; Pseudomonas; Microorganism; Agronomy; Pseudomonas aeruginosa","score_opus":0.013590611574646748,"score_gpt":0.3218804558772438,"score_spread":0.30828984430259704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164375754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996744,0.0023398164,0.000032043718,0.00032899473,0.00018059534,0.00006434909,0.0000224073,0.0000021855117,0.000285654],"genre_scores_gemma":[0.99891543,0.0004930151,0.000060900256,0.000081748956,0.000079707075,0.00000363739,0.000057523393,0.000008615924,0.0002993993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927384,0.0001144796,0.0002052651,0.00020096643,0.000020109315,0.00018532855],"domain_scores_gemma":[0.9994919,0.000069404,0.000057729205,0.00030835843,0.000055865854,0.00001678442],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029958188,0.000097329226,0.00018377698,0.000026582278,0.000022159877,0.000004200712,0.00012159319,0.000061331906,0.000015161465],"category_scores_gemma":[0.0001880088,0.000072010575,0.00008215427,0.000061034192,0.000088248016,7.644577e-7,0.0000757909,0.000061077015,0.0000026068042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101033154,0.000015074868,0.0013958309,0.000027320799,0.000035546607,0.0000026152316,0.000027502052,0.00041236504,0.99541855,0.000028179844,0.0011078106,0.0014281498],"study_design_scores_gemma":[0.00030129732,0.00036540104,0.005307664,0.000027205451,0.000004150618,0.000013799414,0.000016087992,0.0000025649454,0.97809875,0.000007136508,0.015788376,0.00006759184],"about_ca_topic_score_codex":0.000014824604,"about_ca_topic_score_gemma":0.000105736246,"teacher_disagreement_score":0.017319847,"about_ca_system_score_codex":0.0000021031792,"about_ca_system_score_gemma":0.00002364464,"threshold_uncertainty_score":0.2936506},"labels":[],"label_agreement":null},{"id":"W3164735518","doi":"10.1101/2021.05.25.445644","title":"Locus-associated R-loop repression in <i>cis</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Canada Research Chairs","keywords":"Locus (genetics); Loop (graph theory); Psychological repression; Feedback loop; Biology; Genetics; Gene; Combinatorics; Mathematics; Computer science; Gene expression","score_opus":0.007489545497375097,"score_gpt":0.2441107554760425,"score_spread":0.2366212099786674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164735518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894333,0.0055552153,0.0034210659,0.00007036758,0.0009694569,0.00036036098,0.00006671736,0.00009841845,0.000025124893],"genre_scores_gemma":[0.99692684,0.0010904454,0.0012243676,0.00016770579,0.00032170385,0.00011053021,0.0000052460728,0.00012732644,0.00002585829],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738127,0.00013167318,0.000510966,0.0011545053,0.00026750966,0.00055406545],"domain_scores_gemma":[0.99790305,0.000016992168,0.00020808402,0.0014122451,0.00026878796,0.0001908226],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045860134,0.00049444457,0.0004826877,0.00014258991,0.00006620027,0.0001263382,0.00045844752,0.000919802,0.000025489915],"category_scores_gemma":[0.0003623251,0.0005797226,0.00019279162,0.00032473478,0.000052224168,0.000006312252,0.00086207956,0.00064435217,0.0000094002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022514465,0.00013817845,0.0044398527,0.0001296321,0.000088773224,0.000067800494,0.0000060270536,0.0018198884,0.99276173,0.000005203195,0.0005169589,0.0000034481884],"study_design_scores_gemma":[0.0006264807,0.000051882762,0.031812675,0.0004991294,0.00004722244,2.7129303e-8,0.000005309107,0.00032560359,0.9631759,3.637681e-7,0.002713419,0.0007419769],"about_ca_topic_score_codex":0.00005426484,"about_ca_topic_score_gemma":0.00002806839,"teacher_disagreement_score":0.029585814,"about_ca_system_score_codex":0.000104313614,"about_ca_system_score_gemma":0.00037546668,"threshold_uncertainty_score":0.99966544},"labels":[],"label_agreement":null},{"id":"W3164910276","doi":"10.1038/s41596-021-00529-x","title":"BAR-Seq clonal tracking of gene-edited cells","year":2021,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Horizon 2020 Framework Programme; Ministero dell’Istruzione, dell’Università e della Ricerca; Louis-Jeantet Foundation; European Commission; Ministero della Salute; Fondazione Telethon; E-Rare","keywords":"Computational biology; Biology; Genome editing; Gene; Pipeline (software); Genome; Computer science; Genetics","score_opus":0.008424864521099248,"score_gpt":0.33659152801541026,"score_spread":0.328166663494311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164910276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78296536,0.009752427,0.096901774,0.00094273704,0.0020297104,0.09334039,0.0004347626,0.00017949089,0.013453335],"genre_scores_gemma":[0.9733021,0.000021871521,0.01651567,0.00030088567,0.0009351761,0.007946299,0.00014630398,0.000043201668,0.00078849075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999198,0.000026016882,0.0001835669,0.0002614281,0.00015499567,0.00017598679],"domain_scores_gemma":[0.99941015,0.000009340712,0.000049992825,0.00029533927,0.00017997406,0.000055188277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010083696,0.000121546975,0.00013757494,0.000023238095,0.000026170936,0.000015658232,0.00014101215,0.00034904238,0.00005243621],"category_scores_gemma":[0.00007165575,0.00012063876,0.0001027447,0.000103137696,0.000022679948,0.000001951141,0.00005677137,0.0002273842,0.0000030857611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003129789,0.000045229,0.00064469135,0.00007575584,0.000029044004,0.000009166235,0.00001639725,0.0002763914,0.99595356,0.000051299154,0.0015977651,0.0012693977],"study_design_scores_gemma":[0.00042336993,0.00007431572,0.001688695,0.000036154077,0.0000075049816,0.00001922423,0.000012515586,0.00004417326,0.92441463,0.000027937453,0.07312594,0.00012551468],"about_ca_topic_score_codex":8.238145e-7,"about_ca_topic_score_gemma":0.0000036750225,"teacher_disagreement_score":0.19033672,"about_ca_system_score_codex":0.0000061179426,"about_ca_system_score_gemma":0.00008745377,"threshold_uncertainty_score":0.4919506},"labels":[],"label_agreement":null},{"id":"W3166571408","doi":"10.1101/2021.05.29.446205","title":"Decentralizing cell-free RNA sensing with the use of low-cost cell extracts","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias; Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Agencia Nacional de Investigación y Desarrollo; Pontificia Universidad Católica de Chile; Comisión Nacional de Investigación Científica y Tecnológica; Danmarks Tekniske Universitet; University of Toronto; University of Minnesota","keywords":"RNA; Lysis; Biosensor; Computer science; Cell; Computational biology; Nanotechnology; Gene; Chemistry; Biology; Materials science; Biochemistry","score_opus":0.012631308892515056,"score_gpt":0.2237971283771352,"score_spread":0.21116581948462015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166571408","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9577395,0.0029808432,0.03811983,0.00007992669,0.0004313448,0.0005015059,0.00009062957,0.000046007222,0.000010423374],"genre_scores_gemma":[0.98242503,0.0007241554,0.016253512,0.00014199343,0.000284217,0.00002152747,0.0000023301195,0.00013652889,0.000010721751],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978708,0.0000974457,0.00038988478,0.0007952438,0.00030957808,0.0005370515],"domain_scores_gemma":[0.99703985,0.000043199052,0.00031792506,0.0019797056,0.00042997402,0.00018935459],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023915453,0.0005033587,0.00041668714,0.000078512145,0.000108882596,0.00020861927,0.0005285253,0.00043457953,0.000008539426],"category_scores_gemma":[0.000116662944,0.00044184653,0.00017742331,0.00023113556,0.00011170295,0.0000107469805,0.0006740143,0.00050050556,0.0000021907072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030129284,0.00007443506,0.0005072845,0.00043120023,0.00009360028,0.000045130066,0.000016373204,0.008865668,0.9893396,0.000002561123,0.00058917416,0.000004866316],"study_design_scores_gemma":[0.00046659738,0.000037369035,0.0053097517,0.00029452264,0.00012352463,8.5857835e-8,0.000014406142,0.00047059244,0.9868317,4.8474202e-8,0.0059114043,0.0005399623],"about_ca_topic_score_codex":0.000052542127,"about_ca_topic_score_gemma":0.000019007928,"teacher_disagreement_score":0.024685523,"about_ca_system_score_codex":0.000045908797,"about_ca_system_score_gemma":0.00043228283,"threshold_uncertainty_score":0.9998033},"labels":[],"label_agreement":null},{"id":"W3166866690","doi":"10.1016/b978-0-12-823808-0.00012-2","title":"Human induced pluripotent stem cells for modeling of herpes simplex virus 1 infections","year":2021,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Herpes simplex virus; Induced pluripotent stem cell; Biology; Virus; Latent Virus; Virology; Virus latency; Lytic cycle; Encephalitis; Embryonic stem cell; Stem cell; Disease; Latency (audio); Neuroscience; Immunology; Viral replication; Medicine; Genetics; Pathology; Computer science","score_opus":0.02451205692165875,"score_gpt":0.2902871021570562,"score_spread":0.26577504523539747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166866690","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08918922,0.008200122,0.014220427,0.000028731027,0.0014551816,0.0025240025,0.00058060617,0.00008789952,0.8837138],"genre_scores_gemma":[0.33999702,0.0002089009,0.00056545314,0.00007000857,0.00062625343,0.000093017006,0.00016858094,0.00015914456,0.65811163],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988392,0.000010560139,0.00041123712,0.0004059482,0.00011969636,0.00021333586],"domain_scores_gemma":[0.999167,0.000008272056,0.00012667313,0.00045589695,0.00016554604,0.00007660768],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008408524,0.00030425526,0.00036655556,0.00007040015,0.00008867118,0.00001777873,0.00014385727,0.00038957613,0.000021155147],"category_scores_gemma":[0.0000041727712,0.0003326013,0.0003540248,0.000007983607,0.000030339643,0.0000010022441,0.00012784777,0.00013355476,0.0000020626965],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008243589,0.00002119381,3.3612318e-7,0.00022952228,0.00026313387,0.0000021073242,0.000045177985,0.0029000433,0.5046013,0.00039671868,0.000046291603,0.49148592],"study_design_scores_gemma":[0.0003539873,0.00021029223,5.049784e-7,0.00016851671,0.00014859391,0.0000051356574,0.000023838978,0.00049606053,0.37689117,0.00033110494,0.6209555,0.0004152915],"about_ca_topic_score_codex":0.0000022710765,"about_ca_topic_score_gemma":0.00008933488,"teacher_disagreement_score":0.6209092,"about_ca_system_score_codex":0.000020044257,"about_ca_system_score_gemma":0.00008431165,"threshold_uncertainty_score":0.9999126},"labels":[],"label_agreement":null},{"id":"W3167454441","doi":"10.1007/s11248-021-00264-9","title":"Data challenges for future plant gene editing: expert opinion","year":2021,"lang":"en","type":"article","venue":"Transgenic Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canada First Research Excellence Fund","keywords":"Biology; Computational biology; Genome editing; Gene; Expert opinion; Genetics; Data science; Genome; Computer science","score_opus":0.20010753486377159,"score_gpt":0.4675306630684631,"score_spread":0.2674231282046915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167454441","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.174505,0.6703319,0.116286196,0.025396438,0.0048079477,0.0018672257,0.0031434118,0.0001122165,0.0035496855],"genre_scores_gemma":[0.7679326,0.19594012,0.011116234,0.00014045127,0.01513416,0.00021876667,0.008422743,0.00011119025,0.0009837165],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99863297,0.000068190115,0.00014042995,0.0005189372,0.00024383904,0.00039565834],"domain_scores_gemma":[0.9988728,0.000034888875,0.000010116788,0.00083825295,0.00014471519,0.000099191944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059847336,0.00010529731,0.000109928216,0.000035913377,0.000102430444,0.000025529476,0.00043691407,0.00014584385,0.000028804738],"category_scores_gemma":[0.00007403995,0.00010321473,0.00006184458,0.00007698328,0.00003611331,0.0000034239256,0.00014799615,0.00014609566,0.000004562663],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008827556,0.00007176487,0.000012308799,0.00012876438,0.0000907871,0.000006380293,0.0003305414,0.000043955766,0.952382,0.0001937734,0.020429775,0.026221655],"study_design_scores_gemma":[0.00037591986,0.00009559571,0.00013590108,0.000011194539,0.0000022154845,0.000017027842,0.0006124567,0.00021924858,0.4228281,0.000026488618,0.5755824,0.000093462484],"about_ca_topic_score_codex":0.0000037959137,"about_ca_topic_score_gemma":0.00007058466,"teacher_disagreement_score":0.5934276,"about_ca_system_score_codex":0.000007458633,"about_ca_system_score_gemma":0.00012479528,"threshold_uncertainty_score":0.42089742},"labels":[],"label_agreement":null},{"id":"W3168019520","doi":"10.1158/1557-3265.ovcasymp18-gmm-027","title":"Abstract GMM-027: DYNLL1 INHIBITS DNA END RESECTION IN BRCA1-DEFICIENT CELLS AND REGULATES PARP INHIBITOR SENSITIVITY","year":2019,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Olaparib; Cancer research; Homologous recombination; DNA repair; PARP inhibitor; Genome instability; Ovarian cancer; Cisplatin; Chemistry; Molecular biology; Germline; Ovarian carcinoma; DNA damage; DNA; Poly ADP ribose polymerase; Cancer; Biology; Polymerase; Genetics; Gene; Chemotherapy","score_opus":0.04839840193250962,"score_gpt":0.44204335009585777,"score_spread":0.39364494816334816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168019520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99699306,0.0013826187,0.00002407528,0.00027117005,0.00041150182,0.0003601132,0.000027862068,0.000009679575,0.0005198865],"genre_scores_gemma":[0.9974715,0.0013814322,0.00004048814,0.000046151566,0.00044137973,0.000024235202,0.000027414513,0.000024225646,0.000543148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980057,0.00021231778,0.0003793613,0.0006218672,0.00032578158,0.00045501092],"domain_scores_gemma":[0.9990573,0.00023745591,0.000043071333,0.00037331568,0.00012884654,0.0001599909],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026178437,0.00013576905,0.00021732046,0.00008064174,0.000060255028,0.00004394302,0.00009740837,0.0002746314,0.00006862209],"category_scores_gemma":[0.00024617097,0.0001308316,0.00007474263,0.00018088588,0.00018504831,0.0000061322257,0.0002496073,0.0005383453,0.000038440896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034758844,0.000112871414,0.019354215,0.00010512216,0.000019406603,0.000010849328,0.00005004125,0.00082624186,0.9672397,0.000010759549,0.0019731736,0.009950023],"study_design_scores_gemma":[0.0009976658,0.0004321663,0.1862629,0.000106665895,0.000004089173,0.000004820575,0.00010476567,0.00051756727,0.7981575,0.00003478784,0.013168653,0.00020838412],"about_ca_topic_score_codex":0.0003044846,"about_ca_topic_score_gemma":0.001091457,"teacher_disagreement_score":0.16908218,"about_ca_system_score_codex":0.000046719433,"about_ca_system_score_gemma":0.00013215067,"threshold_uncertainty_score":0.5335158},"labels":[],"label_agreement":null},{"id":"W3168292662","doi":"10.15252/msb.202110207","title":"A genome‐scale yeast library with inducible expression of individual genes","year":2021,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Government of Canada; National Institutes of Health; University of Toronto; Office of Extramural Research, National Institutes of Health; Princeton University","keywords":"Griffin; Library science; Research centre; Biology; History; Classics; Computer science","score_opus":0.006690018935849069,"score_gpt":0.2538359586395523,"score_spread":0.24714593970370322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168292662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95358247,0.014302992,0.030716866,0.000026522705,0.00016242398,0.00014890278,0.00007435731,0.000018751536,0.0009667216],"genre_scores_gemma":[0.99683005,0.00013520707,0.0020112046,0.000049121685,0.00013008094,0.00003181226,0.0004928379,0.000035334815,0.0002843703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894494,0.00010999583,0.00022816897,0.00038820287,0.00009758143,0.00023113085],"domain_scores_gemma":[0.9993291,0.0000047320536,0.000077294855,0.00045127238,0.00006113736,0.000076472985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081929145,0.00016104897,0.00023174679,0.00005615508,0.000029579158,0.000020060588,0.00020151613,0.0002141901,0.000018935287],"category_scores_gemma":[0.000011548248,0.00013883707,0.00006874111,0.00014040557,0.00006193314,0.000003333908,0.00021620214,0.000072262636,0.0000035939772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023860823,0.000036637666,0.0038251106,0.00006290749,0.00006618796,0.000023047782,0.000046795754,0.00078419613,0.9946555,0.00006067969,0.00007158,0.00034353224],"study_design_scores_gemma":[0.00036868014,0.00022029316,0.0020003205,0.000035564703,0.000021214551,0.00011481162,0.00015692423,0.000014654171,0.9793268,0.000006840651,0.0175567,0.00017721856],"about_ca_topic_score_codex":0.0000064908995,"about_ca_topic_score_gemma":0.0000033400265,"teacher_disagreement_score":0.04324757,"about_ca_system_score_codex":0.0000032451337,"about_ca_system_score_gemma":0.00010045449,"threshold_uncertainty_score":0.56616116},"labels":[],"label_agreement":null},{"id":"W3168435431","doi":"10.1101/2021.06.08.447622","title":"An Efficient and Cost-effective Purification Methodology for SaCas9 Nuclease","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Ted Rogers Centre for Heart Research; University of Toronto","funders":"University of Toronto","keywords":"Nuclease; Cas9; Simplicity; Scalability; CRISPR; Computer science; Biochemical engineering; Chemistry; Process engineering; Engineering; Biochemistry; DNA; Database","score_opus":0.019877870648792453,"score_gpt":0.3034994710632382,"score_spread":0.2836216004144458,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168435431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75197387,0.002606706,0.24294859,0.00004505406,0.00053217437,0.001700454,0.00013730877,0.000054258406,0.0000015886083],"genre_scores_gemma":[0.9519534,0.00026592796,0.045916647,0.00010961378,0.00044972356,0.0012000861,0.000006698558,0.00009592512,0.0000019631489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979891,0.00020289075,0.00028203393,0.0010558837,0.0001112761,0.0003587724],"domain_scores_gemma":[0.9982494,0.000056728913,0.00015029166,0.0009501328,0.00036390193,0.00022953545],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006614015,0.0003676848,0.0003639679,0.0000966939,0.000105990766,0.000115786046,0.00024105374,0.0005629147,0.0000059443355],"category_scores_gemma":[0.00036003382,0.00042641172,0.000121563215,0.00010430171,0.00008160949,0.00000420576,0.0002317955,0.0002505695,0.0000016205839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057939073,0.00009431802,0.0003193208,0.00023262261,0.00011064208,0.000004944547,0.000013524349,0.00313115,0.99582076,0.00009949282,0.000049721162,0.00006554738],"study_design_scores_gemma":[0.0005462049,0.0001711116,0.023991013,0.000060463823,0.0001298762,7.7079974e-8,0.000013008798,0.0042890483,0.9642909,7.609049e-7,0.005975346,0.0005321896],"about_ca_topic_score_codex":0.000014203827,"about_ca_topic_score_gemma":0.0000032361245,"teacher_disagreement_score":0.19997956,"about_ca_system_score_codex":0.000050072842,"about_ca_system_score_gemma":0.00017364496,"threshold_uncertainty_score":0.99981874},"labels":[],"label_agreement":null},{"id":"W3170311810","doi":"10.2139/ssrn.3385124","title":"One Anti-CRISPR to Rule Them All: Potent Inhibition of Cas9 Homologs Used for Genome Editing","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada); University of Toronto","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Genome; Cas9; Genetics; Biology; Computer science; Gene","score_opus":0.00813783748958411,"score_gpt":0.2637757507930126,"score_spread":0.25563791330342844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170311810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91771847,0.00081068306,0.08068967,0.00028839527,0.00015583164,0.00023420801,0.000011728144,0.0000065829436,0.00008440975],"genre_scores_gemma":[0.9976318,0.0006114003,0.0008737605,0.00009157871,0.00045374854,0.000008647994,0.000043472144,0.00002901417,0.00025659855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984869,0.000019284797,0.00023706307,0.00019677125,0.00012241924,0.00093758194],"domain_scores_gemma":[0.99957323,0.000008830738,0.00009330443,0.00016368234,0.00009400392,0.00006696877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055056514,0.000118969954,0.00016950481,0.000053367115,0.000046871308,0.000014099585,0.00012507668,0.00009312707,0.000009654514],"category_scores_gemma":[0.000031893844,0.00012283468,0.00012482387,0.000056856235,0.000012703764,0.0000043346954,0.000047444253,0.0002755998,0.000010289676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003502665,0.00004322507,0.00058758876,0.00002040295,0.00011696592,4.899085e-7,0.00006003093,0.0012783958,0.99553615,0.00063288887,0.000039638388,0.001649207],"study_design_scores_gemma":[0.0015464547,0.0013851471,0.002272915,0.000037327325,0.00006498428,0.00024209292,0.0006986633,0.00010595237,0.98524326,0.004030695,0.004057697,0.00031478074],"about_ca_topic_score_codex":0.000015329673,"about_ca_topic_score_gemma":0.00005003906,"teacher_disagreement_score":0.07991329,"about_ca_system_score_codex":0.0000870833,"about_ca_system_score_gemma":0.00022950089,"threshold_uncertainty_score":0.5009053},"labels":[],"label_agreement":null},{"id":"W3172071691","doi":"10.1089/regen.2021.0003","title":"CRISPR-Cas9—The Potential “Holy Grail” for Generating Biomedically Relevant Cells through Cell Fate Engineering","year":2021,"lang":"en","type":"article","venue":"Re GEN Open","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba; Research Institute in Oncology and Hematology","funders":"","keywords":"CRISPR; Genome editing; Cas9; Cell fate determination; Biology; Computational biology; Transdifferentiation; Progenitor cell; Regenerative medicine; Stem cell; Cell biology; Gene; Genetics; Transcription factor","score_opus":0.0112815489981041,"score_gpt":0.2966749008955536,"score_spread":0.2853933518974495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172071691","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.27842307,0.0058670384,0.7104102,0.0013890399,0.0014809587,0.0010826756,0.00011073171,0.000039774048,0.0011965465],"genre_scores_gemma":[0.87992704,0.00094584783,0.110896006,0.0010235661,0.0015751398,0.00016200752,0.00038499216,0.00011981603,0.0049655805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987006,0.00003192091,0.00028677075,0.00044841517,0.00014693884,0.0003853133],"domain_scores_gemma":[0.99924296,0.000022655975,0.00005811675,0.00048066728,0.0001043236,0.00009124572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025506897,0.00020022613,0.00018712472,0.000016460466,0.00016373122,0.00016611222,0.0004958727,0.00014776665,0.000054716416],"category_scores_gemma":[0.0000699992,0.00017119932,0.00014226887,0.000106925945,0.000026568288,0.0000075839553,0.00048586173,0.00011926405,0.000012595527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015192952,0.000025459314,0.0000040526734,0.00005616863,0.000053736843,0.000017690189,0.000103343424,0.009848099,0.97877717,0.000014510889,0.009789837,0.0012947264],"study_design_scores_gemma":[0.0005409127,0.00008362911,0.000038045247,0.00001817774,0.00004034165,0.000025886655,0.0001649299,0.0060936715,0.8065729,0.000022601602,0.18616283,0.00023606619],"about_ca_topic_score_codex":0.000020939475,"about_ca_topic_score_gemma":0.000014939747,"teacher_disagreement_score":0.60150397,"about_ca_system_score_codex":0.000013471605,"about_ca_system_score_gemma":0.00011643153,"threshold_uncertainty_score":0.6981306},"labels":[],"label_agreement":null},{"id":"W3172824231","doi":"10.3389/fimmu.2021.642343","title":"Evolutionary Comparative Analyses of DNA-Editing Enzymes of the Immune System: From 5-Dimensional Description of Protein Structures to Immunological Insights and Applications to Protein Engineering","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Context (archaeology); Biology; Computational biology; DNA; Immune system; Gene; Cytidine deaminase; Systems biology; Genetics","score_opus":0.025098578710172886,"score_gpt":0.30543379466309273,"score_spread":0.2803352159529198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172824231","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038728643,0.9420662,0.017629547,0.0000054932198,0.00021410291,0.0012478027,0.00009599462,0.0000057780885,0.000006449687],"genre_scores_gemma":[0.6682611,0.2451126,0.083589785,0.000007078954,0.00026412177,0.0018613407,0.00074895634,0.00008168536,0.00007332296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984519,0.00018048684,0.00073373097,0.0003559391,0.00011200265,0.0001659395],"domain_scores_gemma":[0.9990835,0.000027486432,0.0003082003,0.00042861336,0.0001251019,0.000027058068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083245875,0.0002558615,0.0011312398,0.00022601016,0.00003590328,0.0000047062995,0.000308724,0.00032496857,0.0000023554571],"category_scores_gemma":[0.000095572505,0.00020155606,0.00018863822,0.00035826128,0.00012586956,0.0000039065103,0.00035749364,0.00020178022,2.0072031e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005332153,0.00006901473,0.000030390864,0.0023137038,0.0009871136,0.0000012653636,0.00017188065,0.002863746,0.9732693,0.0007448253,0.000048003756,0.019447459],"study_design_scores_gemma":[0.0005916605,0.00042375707,0.0025839775,0.011658186,0.0004440201,0.00003053526,0.0011940615,0.00016830672,0.8923586,0.00008833208,0.08983119,0.00062735885],"about_ca_topic_score_codex":0.000096433505,"about_ca_topic_score_gemma":0.000007950324,"teacher_disagreement_score":0.6969536,"about_ca_system_score_codex":0.00005579804,"about_ca_system_score_gemma":0.00011289665,"threshold_uncertainty_score":0.8219217},"labels":[],"label_agreement":null},{"id":"W3173605799","doi":"10.3390/plants10071264","title":"Control of Plant Viral Diseases by CRISPR/Cas9: Resistance Mechanisms, Strategies and Challenges in Food Crops","year":2021,"lang":"en","type":"review","venue":"Plants","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Universiti Malaysia Sabah","keywords":"CRISPR; Cas9; Biology; Genome editing; Genome; Biotechnology; Genetics; Food security; Computational biology; Agriculture; Gene; Ecology","score_opus":0.026349273300307376,"score_gpt":0.30065926530984644,"score_spread":0.27430999200953904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173605799","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001606488,0.9956321,0.00080267974,0.0000107886935,0.00008507511,0.00022239125,0.0030202076,0.0000062071495,0.00005987189],"genre_scores_gemma":[0.012700545,0.9862799,0.0000790083,0.000006526879,0.000053556185,0.00004371524,0.0007822184,0.000027398939,0.00002710616],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989085,0.0000734296,0.00030924985,0.00038946877,0.00010368617,0.00021566718],"domain_scores_gemma":[0.999525,0.00004032228,0.00010829929,0.0002442098,0.000017162538,0.00006497532],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007371365,0.00027053233,0.0007852751,0.00004998861,0.000018359819,0.00002522357,0.00014032939,0.00022477376,0.0000037017053],"category_scores_gemma":[0.000029101508,0.0002471237,0.000102088,0.000029730063,0.000029214794,0.0000031800969,0.000059664242,0.00010321591,4.5516316e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048252684,0.0009065671,0.000043139156,0.1465358,0.003389614,0.00050201436,0.00035401655,0.00008240583,0.02090127,0.009020201,0.0078513,0.80993116],"study_design_scores_gemma":[0.00054209476,0.00017436255,0.000024075487,0.00400907,0.00017155988,0.000040442552,0.00018749478,0.000004220298,0.0017985473,0.00008592725,0.9925281,0.00043409958],"about_ca_topic_score_codex":0.0000061589467,"about_ca_topic_score_gemma":0.00014731697,"teacher_disagreement_score":0.9846768,"about_ca_system_score_codex":0.0000074323025,"about_ca_system_score_gemma":0.00010209937,"threshold_uncertainty_score":0.9999981},"labels":[],"label_agreement":null},{"id":"W3174027460","doi":"10.1039/d1cc02546e","title":"CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2","year":2021,"lang":"en","type":"article","venue":"Chemical Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Canadian Institutes of Health Research; Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Alberta Precision Laboratories","keywords":"CRISPR; Colloidal gold; Nanoparticle; RNA; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Cleavage (geology); Coronavirus disease 2019 (COVID-19); Chemistry; Nanotechnology; 2019-20 coronavirus outbreak; Combinatorial chemistry; Virology; Biology; Materials science; Biochemistry; Infectious disease (medical specialty); Gene; Medicine","score_opus":0.03403935691764336,"score_gpt":0.3445082914423324,"score_spread":0.31046893452468904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174027460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.970739,0.00252958,0.025857093,0.0002451583,0.000058613263,0.00015691499,0.000029572539,0.000019202946,0.00036485697],"genre_scores_gemma":[0.9941993,0.00018377007,0.005100074,0.0000674841,0.000035671826,0.000060947692,0.00028855502,0.0000134555585,0.00005077514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994574,0.000025502253,0.00019800662,0.00014474685,0.000057122317,0.000117210875],"domain_scores_gemma":[0.99893606,0.000080952734,0.000054590688,0.00068222545,0.00021701759,0.000029153833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008134338,0.00007197393,0.00009685601,0.0000307431,0.000042991258,0.000009012039,0.00021672375,0.00009796689,0.0000011753322],"category_scores_gemma":[0.0005848734,0.0000829194,0.00007444633,0.00027339693,0.00005937176,0.0000031070147,0.00014414584,0.00006380478,0.0000030122276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014732344,0.000076492026,0.00007100953,0.000018371142,0.000021875287,7.169803e-8,0.000019828394,0.000012314866,0.9971968,0.000067248686,0.0003446652,0.0021565817],"study_design_scores_gemma":[0.00034846138,0.000045208082,0.00013988437,0.000007680207,0.000024416664,0.0000042008,0.000030927084,0.001630309,0.97939926,0.00006814876,0.01821449,0.00008702979],"about_ca_topic_score_codex":0.000007869668,"about_ca_topic_score_gemma":0.000024689527,"teacher_disagreement_score":0.023460258,"about_ca_system_score_codex":0.000015157327,"about_ca_system_score_gemma":0.000037119175,"threshold_uncertainty_score":0.3381355},"labels":[],"label_agreement":null},{"id":"W3174321621","doi":"10.1101/2021.06.18.448732","title":"Zebrafish Cre/ <i>lox</i> regulated UFlip alleles generated by CRISPR/Cas targeted integration provide cell-type specific conditional gene inactivation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Genetics; Gene targeting; Gene; CRISPR; Cre recombinase; Cas9; Reporter gene; Gene expression; Transgene","score_opus":0.007834032369720684,"score_gpt":0.225982853544397,"score_spread":0.21814882117467632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174321621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8912274,0.0064526224,0.09984157,0.00014898399,0.0010477448,0.0007009984,0.00039291664,0.00017743703,0.000010321769],"genre_scores_gemma":[0.98838437,0.0013087542,0.008286619,0.00023232934,0.00086202484,0.00014882922,0.0005394101,0.00019221076,0.000045444693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99677545,0.000152777,0.0006989062,0.0013997668,0.00041455595,0.00055853673],"domain_scores_gemma":[0.9970618,0.00002009987,0.00039084937,0.0010994027,0.0011731285,0.00025471137],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029809083,0.0007344633,0.00051904767,0.00017557488,0.00018726275,0.00031989295,0.00041683027,0.0010019161,0.00008803064],"category_scores_gemma":[0.0001616428,0.00086173794,0.00018510547,0.00047902865,0.000097828895,0.000027279535,0.0003305604,0.0006247906,0.000014230974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006462131,0.00020113544,0.00024175318,0.00012106897,0.00017569307,0.000019890333,0.000013108994,0.0021177349,0.9854943,0.000020182873,0.011525698,0.0000047993562],"study_design_scores_gemma":[0.0006372921,0.00011640141,0.0053391824,0.00009003362,0.000074308504,1.5817422e-7,0.000015478367,0.0013192128,0.97321814,0.0000010476269,0.018274862,0.0009138612],"about_ca_topic_score_codex":0.000052787287,"about_ca_topic_score_gemma":0.0000069091852,"teacher_disagreement_score":0.09715698,"about_ca_system_score_codex":0.00019460567,"about_ca_system_score_gemma":0.00057559594,"threshold_uncertainty_score":0.99938333},"labels":[],"label_agreement":null},{"id":"W3174508705","doi":"10.1101/2021.07.01.450725","title":"Programmable Cleavage of Double-stranded DNA by Combined Action of Argonaute CbAgo from <i>Clostridium butyricum</i> and Nuclease Deficient RecBC Helicase from <i>E.coli</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Nuclease; RecBCD; Helicase; DNA; Biology; Molecular biology; Biochemistry; DNA repair; RNA; Gene","score_opus":0.010077762032583443,"score_gpt":0.23706623266069643,"score_spread":0.22698847062811298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174508705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874797,0.0056504016,0.0038720036,0.00006163866,0.00051665754,0.00065399706,0.0016996543,0.000059032875,0.000006915625],"genre_scores_gemma":[0.9938553,0.0021034041,0.0035674882,0.0000583271,0.00017512852,0.0000853699,0.0000548521,0.00009591952,0.0000042053066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975542,0.00008317295,0.000669324,0.001003207,0.000300245,0.00038986283],"domain_scores_gemma":[0.9978918,0.00003065592,0.00043432927,0.0010638529,0.00032139398,0.00025799542],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021918907,0.000495848,0.00064822874,0.0000821391,0.00006874311,0.000089344794,0.00031737424,0.0006233265,0.000014624838],"category_scores_gemma":[0.000053779742,0.0005692748,0.0002021114,0.00022775494,0.00012824916,0.000011519792,0.00042340538,0.00036605084,0.0000017037211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042019063,0.00032380354,0.0008356663,0.00030604814,0.0002615375,0.000012609523,0.000010976881,0.00011802579,0.99710816,0.0000068748136,0.0005801168,0.000015968924],"study_design_scores_gemma":[0.0020747087,0.00016505562,0.0027873311,0.0002495846,0.00023410386,3.5188137e-8,0.000018674002,0.00015495543,0.9907495,9.936366e-7,0.003044495,0.0005205555],"about_ca_topic_score_codex":0.00045603633,"about_ca_topic_score_gemma":0.000016653928,"teacher_disagreement_score":0.0063756066,"about_ca_system_score_codex":0.00004382203,"about_ca_system_score_gemma":0.00025498917,"threshold_uncertainty_score":0.99967587},"labels":[],"label_agreement":null},{"id":"W3174749099","doi":"10.1007/s10460-021-10235-9","title":"Citizen views on genome editing: effects of species and purpose","year":2021,"lang":"en","type":"article","venue":"Agriculture and Human Values","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"Libera Università di Bolzano; Georg-August-Universität Göttingen; Genome British Columbia","keywords":"German; Product (mathematics); Resistance (ecology); Perception; Public opinion; Quality (philosophy); Affect (linguistics); Risk perception; Psychology; Sample (material); Marketing; Demographics; Business; Geography; Biology; Political science; Sociology; Demography; Ecology","score_opus":0.007426531476913432,"score_gpt":0.2563411678274043,"score_spread":0.24891463635049085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174749099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887364,0.0083020935,0.00007607075,0.000049216345,0.00006339124,0.00008018929,0.000005399239,0.000006225254,0.0026810516],"genre_scores_gemma":[0.9958771,0.00081755104,0.0001431013,0.00008210438,0.0004793475,0.0000056146732,0.000065923574,0.0000062563927,0.0025229866],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956447,0.000017145669,0.000090190406,0.0001786338,0.000056081957,0.00009349367],"domain_scores_gemma":[0.9997866,0.000009604684,0.0000261472,0.00009889135,0.00003760119,0.00004113348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000033762655,0.00009715046,0.00012257104,0.00001224458,0.0000623821,0.000018952145,0.00003640805,0.000064126114,0.000006890984],"category_scores_gemma":[0.000020423195,0.00007031045,0.00003752235,0.000027977694,0.00003818142,0.0000014894912,0.000053941792,0.00004442393,6.080422e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000022051622,0.000020915077,0.00042821813,0.00009583128,0.000028697197,0.000005721191,0.00021036301,0.000005299838,0.9962762,0.00057617336,0.001957715,0.00039263134],"study_design_scores_gemma":[0.00025465686,0.0002383877,0.095573865,0.000041647774,0.000032619715,0.00001793178,0.00018886045,4.884169e-7,0.8500938,0.00015914503,0.05327526,0.00012334772],"about_ca_topic_score_codex":0.0000023688222,"about_ca_topic_score_gemma":0.000014399946,"teacher_disagreement_score":0.14618243,"about_ca_system_score_codex":0.0000017408256,"about_ca_system_score_gemma":0.0000035294308,"threshold_uncertainty_score":0.28671768},"labels":[],"label_agreement":null},{"id":"W3174870876","doi":"10.1128/aem.00647-21","title":"Improved Dynamic Range of a Rhamnose-Inducible Promoter for Gene Expression in <i>Burkholderia</i> spp.","year":2021,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Mitacs; Government of Canada","keywords":"Biology; Burkholderia cenocepacia; Promoter; Gene; Genetics; Plasmid; Burkholderia; lac operon; Gene cluster; Mutant; Regulation of gene expression; Reporter gene; Gene expression; Molecular biology; Bacteria; Virulence","score_opus":0.0034975291505154613,"score_gpt":0.21551290471857057,"score_spread":0.2120153755680551,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174870876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99425846,0.0016223552,0.0036364014,0.000020705485,0.00005648681,0.00024839333,0.00009780674,0.000003052992,0.000056337238],"genre_scores_gemma":[0.9950262,0.00037840242,0.003787125,0.00006842726,0.00002752625,0.0000537048,0.0005140444,0.00001686414,0.00012770484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993126,0.000011049598,0.00016018297,0.00032363943,0.000013224416,0.00017932359],"domain_scores_gemma":[0.99975914,0.000006919687,0.00003436187,0.00016795285,0.0000025752133,0.000029073597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054632543,0.00011757917,0.00015648664,0.000019713962,0.000021097921,0.000003081428,0.000054001634,0.00014695052,0.000016258618],"category_scores_gemma":[0.0000030215817,0.000116006646,0.00003982892,0.000020626136,0.00005932183,0.0000012896194,0.00010853358,0.000045705303,9.083697e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049907318,0.0000695803,0.000484303,0.000029695231,0.0000135124355,0.0000010565502,0.000044213983,0.00003012507,0.99837,0.0000020578193,0.00003328028,0.0008723037],"study_design_scores_gemma":[0.0011711351,0.000099422716,0.0012291733,0.000006864435,0.00000848086,0.00003330241,0.000108160944,0.00004463122,0.9947548,0.000023137747,0.0023914706,0.00012942842],"about_ca_topic_score_codex":0.0000023644589,"about_ca_topic_score_gemma":0.000009846057,"teacher_disagreement_score":0.003615172,"about_ca_system_score_codex":0.000009048568,"about_ca_system_score_gemma":0.000009993571,"threshold_uncertainty_score":0.47306138},"labels":[],"label_agreement":null},{"id":"W3175241426","doi":"10.1016/b978-0-12-821389-6.00015-7","title":"CRISPR–Cas systems in bioactive peptide research","year":2021,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Genome editing; Timeline; Computational biology; Biology; Genetics; Gene; Geography","score_opus":0.02808946779042449,"score_gpt":0.34271590921262535,"score_spread":0.31462644142220086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175241426","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00090543454,0.020671474,0.00008525084,0.000027721868,0.0004537405,0.00051503285,0.00004007465,0.0000141662895,0.9772871],"genre_scores_gemma":[0.029495468,0.0010115566,0.00013243205,0.00004188154,0.0007397972,0.00007697298,0.0001286357,0.0001157709,0.9682575],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99803156,0.000071895694,0.00038291558,0.00070546253,0.00035086306,0.0004572909],"domain_scores_gemma":[0.9987954,0.000034613455,0.000071215836,0.0007380046,0.00023264055,0.00012811397],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049397873,0.0003496584,0.0004065301,0.00021671756,0.00006616251,0.000060112754,0.0002784969,0.0005760894,0.000042383697],"category_scores_gemma":[0.000055412085,0.0003724717,0.00017712722,0.000026940941,0.00012158099,0.0000012934024,0.0003051137,0.00067017286,0.000052740725],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012976384,0.000060502825,0.0000876103,0.0009069234,0.0006418226,0.00067524513,0.0006135131,0.00034724845,0.12529512,0.00592703,0.0037216288,0.8615936],"study_design_scores_gemma":[0.00025619246,0.00011343206,0.000048782007,0.00043990454,0.000023740893,0.00004557887,0.000110058776,0.000014537954,0.019021232,0.00020572417,0.9792998,0.00042104436],"about_ca_topic_score_codex":0.000008728004,"about_ca_topic_score_gemma":0.0001786066,"teacher_disagreement_score":0.9755781,"about_ca_system_score_codex":0.000087555316,"about_ca_system_score_gemma":0.00021285776,"threshold_uncertainty_score":0.99987274},"labels":[],"label_agreement":null},{"id":"W3175469080","doi":"10.1096/fasebj.26.1_supplement.1127.8","title":"ALTERNATIVELY SPLICED BNIP3 ISOFORM PROMOTES CELL SURVIVAL BY RECRUITING BCL‐2 TO THE IP3‐RECEPTOR","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Endoplasmic reticulum; Cell biology; Programmed cell death; Mutant; Gene isoform; Biology; Alternative splicing; Unfolded protein response; Receptor; Cell; Apoptosis; Biochemistry; Gene","score_opus":0.015148343844431554,"score_gpt":0.2890217502451039,"score_spread":0.27387340640067237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175469080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809984,0.0019032465,0.013401855,0.0011034441,0.00073041534,0.00019768214,0.00003275482,0.000009549737,0.0016226646],"genre_scores_gemma":[0.9953495,0.00020324143,0.0006627925,0.0002794333,0.0017497626,0.000011643126,0.0000130401595,0.000027413465,0.001703124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989861,0.00007760227,0.00019311337,0.0001267375,0.00019150104,0.00042491997],"domain_scores_gemma":[0.99935794,0.00003323196,0.000088199886,0.00029394976,0.00005687154,0.00016983357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007774491,0.00015237978,0.0001023262,0.000020666137,0.0002683783,0.000068575064,0.0005133182,0.000055313274,0.00007156052],"category_scores_gemma":[0.000101972655,0.00008940321,0.00009216976,0.00007080524,0.000031143823,0.000006882333,0.00017428835,0.00023876522,0.00004446991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002557061,0.000030270749,0.0005695569,0.00000468316,0.00003677996,3.868855e-7,0.0006218534,0.00011349946,0.9841851,0.000010811976,0.010858926,0.0035425697],"study_design_scores_gemma":[0.0002851377,0.000117006915,0.00059492176,0.000011478795,0.000018071018,0.000051950377,0.0005996136,0.000046952886,0.9218659,0.000011577951,0.07624994,0.00014748522],"about_ca_topic_score_codex":0.000012959637,"about_ca_topic_score_gemma":0.00000754377,"teacher_disagreement_score":0.06539102,"about_ca_system_score_codex":0.000018840423,"about_ca_system_score_gemma":0.000026297885,"threshold_uncertainty_score":0.3645757},"labels":[],"label_agreement":null},{"id":"W3175601579","doi":"10.1002/adhm.202100847","title":"The Delivery Challenge of Genome Editing in Human Epithelia","year":2021,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Ikerbasque, Basque Foundation for Science","keywords":"Genome editing; CRISPR; Gene delivery; Translation (biology); Computational biology; Cas9; Computer science; Genetic enhancement; Gene; Biology; Genetics; Messenger RNA","score_opus":0.011722912664809374,"score_gpt":0.3232173990819709,"score_spread":0.31149448641716154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175601579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991245,0.007358299,0.00017079001,0.00059701037,0.00035061312,0.000119450095,0.000039201273,0.000006592206,0.00011308119],"genre_scores_gemma":[0.9965016,0.0025805382,0.00041777917,0.00006889989,0.0002466079,0.000023463006,0.00007675989,0.000016905,0.00006740034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914646,0.00006571695,0.0003007555,0.00019343592,0.00006894424,0.00022468288],"domain_scores_gemma":[0.9995168,0.000014151191,0.00007119373,0.00027039283,0.0000910783,0.000036411846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020158166,0.00008966364,0.00015077383,0.000016600065,0.00007364427,0.000009517537,0.0001004118,0.00007119018,0.000011296099],"category_scores_gemma":[0.00005316874,0.000080000595,0.00003010332,0.00004762283,0.0000258293,0.0000021328008,0.00008330306,0.000045461842,0.0000013319682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001475083,0.000010204713,0.00011070615,0.000098950804,0.0000069457506,0.0000050427484,0.00006775776,0.00018316167,0.99648637,0.00031457326,0.000005703015,0.0026958487],"study_design_scores_gemma":[0.0002431834,0.00008823757,0.002918859,0.000043139204,0.0000022114882,0.0000041771623,0.00025430735,0.0000014236009,0.98947334,0.0003008572,0.0065840515,0.0000862067],"about_ca_topic_score_codex":0.000050276103,"about_ca_topic_score_gemma":0.00040882293,"teacher_disagreement_score":0.007013009,"about_ca_system_score_codex":0.000012663367,"about_ca_system_score_gemma":0.000040242874,"threshold_uncertainty_score":0.32623297},"labels":[],"label_agreement":null},{"id":"W3176758754","doi":"10.1101/2021.06.27.450087","title":"Tracking and Measuring Local Protein Synthesis <i>In Vivo</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Fluorescence; In vivo; Green fluorescent protein; Biophysics; Fluorescent protein; Protein biosynthesis; Yellow fluorescent protein; Translation (biology); Chemistry; Biology; Cell biology; Gene; Messenger RNA; Biochemistry; Genetics; Physics","score_opus":0.009673139613181994,"score_gpt":0.22265041678056796,"score_spread":0.21297727716738596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176758754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762517,0.0059270104,0.017006222,0.00005074783,0.00022752889,0.00042232388,0.000039831342,0.00006176712,0.000012874571],"genre_scores_gemma":[0.99520606,0.00045079694,0.0036559878,0.000050192295,0.0002822263,0.00023563462,2.180343e-7,0.00011422286,0.000004644436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978115,0.00009244961,0.00039066465,0.0010041641,0.0002204962,0.0004807142],"domain_scores_gemma":[0.99883896,0.00001821555,0.00011683701,0.000683073,0.00016007424,0.00018283592],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004305943,0.00045649873,0.0004307578,0.00013184673,0.00006829331,0.0001637722,0.00028097973,0.00055658945,0.000014413655],"category_scores_gemma":[0.00023079437,0.0005496164,0.000121697536,0.00017172832,0.00008522571,0.000007962419,0.00051957025,0.0004442075,0.0000018606878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016347798,0.000049976596,0.0015442193,0.00041112397,0.000070531016,0.000053698295,0.0000067003043,0.0007479758,0.9970479,0.000012142745,0.000017381808,0.000022024453],"study_design_scores_gemma":[0.00024052782,0.000023645856,0.01184977,0.00065469305,0.00004176174,7.853478e-8,0.000011872394,0.000351202,0.98498124,2.6938926e-7,0.0012371445,0.00060781935],"about_ca_topic_score_codex":0.000047027246,"about_ca_topic_score_gemma":0.000025288933,"teacher_disagreement_score":0.018954383,"about_ca_system_score_codex":0.00006894919,"about_ca_system_score_gemma":0.00024924395,"threshold_uncertainty_score":0.99969554},"labels":[],"label_agreement":null},{"id":"W3177406927","doi":"10.21926/obm.genet.2003115","title":"Breeding “CRISPR” Crops&lt;a class=\"tippyShow\" data-tippy-interactive=\"true\" data-tippy-arrow=\"true\" data-tippy-theme=\"light-border\" style=\"cursor:pointer\" data-tippy-content=\"&lt;p style=text-indent:0in;&gt;In loving memory of my beloved wife, Jean Georges.&lt;/p&gt;\"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/a&gt;","year":2020,"lang":"en","type":"article","venue":"OBM Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Quest University Canada","funders":"","keywords":"Food security; Face (sociological concept); CRISPR; Argument (complex analysis); Environmental ethics; Economic shortage; Humanity; Risk analysis (engineering); Computer science; Law and economics; Business; Political science; Sociology; Agriculture; Law; Ecology; Social science; Biology","score_opus":0.033618257677923986,"score_gpt":0.30158652707471256,"score_spread":0.2679682693967886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177406927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80097866,0.063721545,0.06147884,0.006798228,0.007186212,0.0077132746,0.043696344,0.0011925895,0.0072343186],"genre_scores_gemma":[0.92455673,0.010608569,0.013030348,0.0015162193,0.004275321,0.00013968715,0.041321516,0.0012769285,0.0032746815],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9774252,0.000998983,0.005251742,0.008617676,0.00328107,0.004425336],"domain_scores_gemma":[0.9762569,0.00081493263,0.002296002,0.017300783,0.0012373205,0.0020940818],"candidate_categories":["metaepi_narrow","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","open_science","research_integrity"],"category_scores_codex":[0.0035982095,0.0037418818,0.0038516861,0.0010790208,0.0008226131,0.00104288,0.016900448,0.002027853,0.0010651845],"category_scores_gemma":[0.0033864547,0.0040726108,0.000792416,0.0019868112,0.0011039078,0.0007995927,0.020120222,0.002415162,0.00037073003],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015797786,0.0012999052,0.0021031993,0.0011609228,0.0024831565,0.00041783447,0.0014548834,0.004300461,0.87068605,0.00019764362,0.09627521,0.018040968],"study_design_scores_gemma":[0.00968201,0.0016019103,0.0029637557,0.00094030396,0.0019777974,0.00037056342,0.0016053761,0.1554335,0.12889895,0.000041892774,0.69109935,0.0053845677],"about_ca_topic_score_codex":0.00022481405,"about_ca_topic_score_gemma":0.0035434286,"teacher_disagreement_score":0.7417871,"about_ca_system_score_codex":0.00045126938,"about_ca_system_score_gemma":0.0011893924,"threshold_uncertainty_score":0.99999416},"labels":[],"label_agreement":null},{"id":"W3178467951","doi":"10.3389/fgene.2021.646297","title":"Omics Multi-Layers Networks Provide Novel Mechanistic and Functional Insights Into Fat Storage and Lipid Metabolism in Poultry","year":2021,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"University of Tehran","keywords":"Lipid metabolism; Computational biology; Biology; Chemistry; Bioinformatics; Biochemistry","score_opus":0.007461649690830884,"score_gpt":0.23472166102667413,"score_spread":0.22726001133584325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3178467951","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40764752,0.025093839,0.5663786,0.000038187423,0.0006978713,0.000119234704,0.0000053340614,0.0000054730162,0.000013925897],"genre_scores_gemma":[0.9024801,0.006110521,0.090747595,0.00014875583,0.00024766152,0.000020133568,0.000112853944,0.000032909513,0.00009946806],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9989163,0.000037802478,0.0002411688,0.0004450707,0.00009586644,0.00026377104],"domain_scores_gemma":[0.9995691,0.000011290776,0.000039456696,0.0002196841,0.0000503993,0.00011008089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000900278,0.00019963959,0.00021787212,0.0000965538,0.000050857936,0.00003592307,0.00007726437,0.00023049665,0.0000016376764],"category_scores_gemma":[0.0000697591,0.00022367976,0.000033577788,0.0001423476,0.000067099296,0.0000046773935,0.0001651135,0.0001781537,2.0798656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010552883,0.00020529957,0.049055006,0.00012384787,0.00012655018,0.000036610374,0.0006241082,0.08989193,0.8448334,0.00019925978,0.00063527067,0.014163178],"study_design_scores_gemma":[0.008849713,0.00026238512,0.12333712,0.00011231498,0.00016178597,0.00010466924,0.0043953876,0.6396071,0.15328674,0.0008431022,0.06715433,0.0018853603],"about_ca_topic_score_codex":0.000009514324,"about_ca_topic_score_gemma":0.0001389046,"teacher_disagreement_score":0.6915467,"about_ca_system_score_codex":0.000028361299,"about_ca_system_score_gemma":0.00006479969,"threshold_uncertainty_score":0.9121396},"labels":[],"label_agreement":null},{"id":"W3179479670","doi":"10.1007/978-1-0716-1441-9_12","title":"Highly Multiplexed Analysis of CRISPR Genome Editing Outcomes in Mammalian Cells","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Multiplexing; Biology; Genome; Computer science; Genetics; Gene; Telecommunications","score_opus":0.013667573441290465,"score_gpt":0.4000154391507505,"score_spread":0.38634786570946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179479670","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3954064,0.0013004763,0.60276824,0.000067992165,0.00019061037,0.00008875078,0.000026773798,0.0000056060026,0.00014513808],"genre_scores_gemma":[0.47968805,0.00007185718,0.51979774,0.0001473415,0.00003335966,0.00001948238,0.00014456622,0.00002030123,0.0000772757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794227,0.000589965,0.0005223142,0.0005175395,0.00006824877,0.00035965303],"domain_scores_gemma":[0.9991957,0.0000780163,0.00009657288,0.00049988244,0.000073730844,0.00005612679],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007390046,0.00019932188,0.0005704734,0.00037892887,0.000015050641,0.00000699057,0.00021872333,0.00027530998,0.000030752683],"category_scores_gemma":[0.00044963855,0.00020914956,0.00025857563,0.000751679,0.00006610985,0.0000015081677,0.00019797038,0.00015000605,8.840122e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010589499,0.00006241679,0.03228173,0.000018098375,0.00026112865,0.000035225923,0.00005978795,0.009460964,0.95621985,0.000103797815,0.0000021197884,0.0014842593],"study_design_scores_gemma":[0.00045425777,0.000059459966,0.02832663,0.000004889228,0.00010464362,0.0000027521255,0.00010530532,0.00075462286,0.968526,0.00009738493,0.0013641928,0.00019984467],"about_ca_topic_score_codex":0.00009403515,"about_ca_topic_score_gemma":0.00023964167,"teacher_disagreement_score":0.084281646,"about_ca_system_score_codex":0.000019615176,"about_ca_system_score_gemma":0.00004063554,"threshold_uncertainty_score":0.85288715},"labels":[],"label_agreement":null},{"id":"W3181507805","doi":"10.1016/j.jare.2021.07.001","title":"CRISPR/Cas9 gene editing: New hope for Alzheimer's disease therapeutics","year":2021,"lang":"en","type":"review","venue":"Journal of Advanced Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"United Arab Emirates University; Department of Biotechnology, Ministry of Science and Technology, India; Department of Science and Technology, Ministry of Science and Technology, India; Murdoch Children's Research Institute; Takeda Science Foundation","keywords":"CRISPR; Genome editing; Disease; Gene; Cas9; Computational biology; Biology; Genetics; Medicine; Pathology","score_opus":0.1378152482931276,"score_gpt":0.5130109867083946,"score_spread":0.375195738415267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3181507805","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000014529222,0.98514885,0.013385482,0.00014726611,0.00071270665,0.0004835324,0.00004789123,0.0000035735104,0.000056146007],"genre_scores_gemma":[0.000031199514,0.98603356,0.008540218,0.000035569457,0.004411705,0.00002918003,0.00011306655,0.00009844831,0.00070703484],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977278,0.0001765672,0.00067777303,0.00036139405,0.00052785873,0.0005285702],"domain_scores_gemma":[0.99778694,0.0001556279,0.00030010758,0.0004897079,0.0008280556,0.00043954118],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008659169,0.00030285274,0.0008562339,0.00021561547,0.000111680296,0.00007372903,0.00056154624,0.0002561924,0.000014850888],"category_scores_gemma":[0.0005076167,0.00024790704,0.0008045122,0.00026024986,0.00006232074,0.0000064835963,0.00019585683,0.0006976036,0.0000031342536],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006747126,0.000059254715,7.8211474e-7,0.0012241324,0.00061913,0.000048830898,0.000012883443,0.0003661285,0.0020888834,0.000013530455,0.0122835245,0.98321545],"study_design_scores_gemma":[0.0004445794,0.0003669218,0.0000013405026,0.0019125664,0.00052839954,0.000114689225,0.000041375435,0.000007492287,0.0046062777,0.000045099292,0.99169755,0.00023368139],"about_ca_topic_score_codex":8.009661e-7,"about_ca_topic_score_gemma":0.0000014880652,"teacher_disagreement_score":0.98298174,"about_ca_system_score_codex":0.000045343022,"about_ca_system_score_gemma":0.001566399,"threshold_uncertainty_score":0.9999973},"labels":[],"label_agreement":null},{"id":"W3181953750","doi":"10.1016/j.molp.2021.07.010","title":"Highly efficient heritable genome editing in wheat using an RNA virus and bypassing tissue culture","year":2021,"lang":"en","type":"article","venue":"Molecular Plant","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"Youth Innovation Promotion Association of the Chinese Academy of Sciences; Chinese Universities Scientific Fund; Chinese Academy of Sciences; China Agricultural University; National Natural Science Foundation of China","keywords":"Biology; Genome editing; Cas9; Genome; Mutagenesis; Transformation (genetics); Transgene; Genetics; CRISPR; Virus; Brome mosaic virus; Mutant; Genetically modified crops; Gene; Computational biology; RNA; RNA-dependent RNA polymerase","score_opus":0.007126271313292723,"score_gpt":0.2611605942296268,"score_spread":0.25403432291633404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3181953750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9631884,0.007258676,0.02904353,0.000032150274,0.0001299938,0.00008487984,0.00003499509,0.000011982875,0.00021539669],"genre_scores_gemma":[0.99392945,0.00010100926,0.0053952257,0.00011447644,0.00016006963,0.000004599185,0.00021299913,0.000027321548,0.0000548243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990138,0.000046319245,0.0001642792,0.00037416138,0.00010973467,0.00029175245],"domain_scores_gemma":[0.99961734,0.000002902012,0.000027589616,0.0002201435,0.000033912034,0.000098141856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001053107,0.00015721068,0.00014823774,0.000037663427,0.00006859772,0.0000616098,0.00007368582,0.00012370126,0.0000062716185],"category_scores_gemma":[0.000024528648,0.00016751418,0.000025384292,0.00009549638,0.000021854226,0.0000035120206,0.00010135073,0.000103632774,0.0000010414739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073019755,0.000040261442,0.00004361368,0.00002730278,0.000013911557,0.00025864047,0.00015578984,0.029544853,0.96944875,0.000013173819,0.000015408574,0.0004309831],"study_design_scores_gemma":[0.00033008488,0.000067153356,0.0002955396,0.000038770384,0.000015604755,0.00021244332,0.00018046325,0.0058868425,0.98754984,0.0000066415037,0.0051992456,0.00021737115],"about_ca_topic_score_codex":0.000058056805,"about_ca_topic_score_gemma":0.000076917124,"teacher_disagreement_score":0.030741079,"about_ca_system_score_codex":0.000020481126,"about_ca_system_score_gemma":0.00004249926,"threshold_uncertainty_score":0.68310297},"labels":[],"label_agreement":null},{"id":"W3182330586","doi":"10.1111/bioe.12913","title":"From goodness to good looks: Changing images of human germline genetic modification","year":2021,"lang":"en","type":"article","venue":"Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"Canadian Institutes of Health Research","keywords":"Context (archaeology); Trait; Identity (music); Germline; Sociology; Bioethics; Psychology; Aesthetics; Social psychology; Political science; Biology; Law; Genetics; Computer science; Art","score_opus":0.036378485184046856,"score_gpt":0.375443505657528,"score_spread":0.33906502047348114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3182330586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9127713,0.0024929827,0.08378116,0.00032925597,0.00018462556,0.000092245384,0.00007544309,0.000015378528,0.00025760755],"genre_scores_gemma":[0.9911936,0.00013641447,0.00749305,0.00012370857,0.00038123282,0.00001105193,0.00022277322,0.000022634658,0.00041556163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918884,0.000030766045,0.00019815227,0.0002881664,0.00012011238,0.00017394697],"domain_scores_gemma":[0.9993134,0.000012872883,0.000046458135,0.000406726,0.00015260378,0.00006794269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011441382,0.00011250019,0.00012471067,0.000047183406,0.000048845854,0.000016117005,0.00013365778,0.00015756392,0.000017781555],"category_scores_gemma":[0.000071746894,0.00012599968,0.00006155748,0.0001356899,0.000052488766,0.0000013797929,0.00012494459,0.00008393809,0.0000060574694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005087895,0.000033906534,0.0005217684,0.00003224263,0.000026651016,0.0000026871194,0.00028039157,0.00046494688,0.99669564,0.00015043945,0.00010408732,0.0016821244],"study_design_scores_gemma":[0.00018385726,0.00006922611,0.0048980205,0.00002950684,0.000022700007,0.0000028454122,0.0004184585,0.0001203385,0.992384,0.00011050911,0.0016072721,0.00015327155],"about_ca_topic_score_codex":0.000072385315,"about_ca_topic_score_gemma":0.000049806014,"teacher_disagreement_score":0.07842227,"about_ca_system_score_codex":0.000007223224,"about_ca_system_score_gemma":0.00004911387,"threshold_uncertainty_score":0.5138118},"labels":[],"label_agreement":null},{"id":"W3182552702","doi":"10.1038/s41598-021-92514-3","title":"Author Correction: A one-step tRNA-CRISPR system for genome-wide genetic interaction mapping in mammalian cells","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"CRISPR; Transfer RNA; Computational biology; Genome; Biology; Computer science; Genetics; Gene; RNA","score_opus":0.014360956905654082,"score_gpt":0.2779000190962742,"score_spread":0.2635390621906201,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3182552702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8425416,0.0010138839,0.12898017,0.00009933242,0.026263775,0.00048385723,0.0000044280036,0.000036871214,0.000576074],"genre_scores_gemma":[0.9838736,0.000008124025,0.005164738,0.000022101083,0.0002763123,0.00008409836,0.00015303705,0.000027868768,0.010390108],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998145,0.00004055678,0.00051638554,0.0007927639,0.00018263885,0.00032269186],"domain_scores_gemma":[0.9989205,0.000015184262,0.0001511359,0.0006280639,0.00018350218,0.00010159384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053910917,0.00015353324,0.00018096436,0.00013269397,0.0001423949,0.0001576135,0.000089364235,0.0001197661,0.000023832104],"category_scores_gemma":[0.00012246543,0.00017774025,0.0001333066,0.00029589754,0.000035996633,0.000006727992,0.00007583786,0.0000885156,0.000007743485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011565645,0.000046670255,0.0019700655,0.00015441254,0.00002452005,0.00015432882,0.000144335,0.005545744,0.9833775,0.0000020941172,0.006249118,0.0023196114],"study_design_scores_gemma":[0.00018456283,0.000034349752,0.003952324,0.000084484076,0.000019013718,0.00041219156,0.00083635235,0.0017296857,0.76712006,0.000018768662,0.22538726,0.00022091698],"about_ca_topic_score_codex":0.000021646856,"about_ca_topic_score_gemma":0.0001360962,"teacher_disagreement_score":0.21913815,"about_ca_system_score_codex":0.00007657442,"about_ca_system_score_gemma":0.00013429612,"threshold_uncertainty_score":0.72480375},"labels":[],"label_agreement":null},{"id":"W3182870533","doi":"10.1101/2021.07.09.451512","title":"Structural and mechanistic insight into CRISPR-Cas9 inhibition by anti-CRISPR protein AcrIIC4","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Endonuclease; DNA; Plasmid; Biology; Prophage; Cleavage (geology); Genetics; Computational biology; Trans-activating crRNA; Cell biology; Gene; Bacteriophage; Escherichia coli","score_opus":0.006165302458051847,"score_gpt":0.23318184842660172,"score_spread":0.22701654596854987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3182870533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9655435,0.0091556,0.023603695,0.000112910886,0.0006224179,0.00069492677,0.00015680403,0.00010484138,0.0000052973396],"genre_scores_gemma":[0.99310243,0.00070225855,0.00526905,0.00014084723,0.00044679822,0.00016933514,0.000014853447,0.00014501737,0.000009428698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99729866,0.00010947789,0.0004853199,0.0012882997,0.00029432052,0.00052392925],"domain_scores_gemma":[0.99812853,0.000010387968,0.0002066581,0.0009887918,0.00037524712,0.0002903936],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023269089,0.00066183426,0.00051483786,0.00012706795,0.00018880359,0.0003228585,0.00027854656,0.0007668452,0.00002590115],"category_scores_gemma":[0.0001977201,0.0007453062,0.00014072064,0.0002059278,0.00011110958,0.00001683294,0.0008280414,0.0005637175,0.0000053516546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017672082,0.00003713604,0.00031062873,0.0005099668,0.00011968873,0.00003974867,0.000020892658,0.000074743315,0.9985444,0.00006533388,0.00025149056,0.000008306481],"study_design_scores_gemma":[0.0004697284,0.000099175144,0.0033122983,0.00026330087,0.00008869606,2.1448683e-7,0.000010252237,0.00043377015,0.9908809,0.000003858197,0.003563612,0.0008741844],"about_ca_topic_score_codex":0.000067544075,"about_ca_topic_score_gemma":0.000009580817,"teacher_disagreement_score":0.027558906,"about_ca_system_score_codex":0.00007664629,"about_ca_system_score_gemma":0.00026128488,"threshold_uncertainty_score":0.9994998},"labels":[],"label_agreement":null},{"id":"W3183228708","doi":"10.15252/embr.202052190","title":"Homologous recombination is reduced in female embryonic stem cells by two active X chromosomes","year":2021,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Hospital Universiti Sains Malaysia; Yasuda Memorial Medical Foundation; Kanazawa University; Kindai University","keywords":"Homologous recombination; Embryonic stem cell; Biology; Homologous chromosome; Cell biology; Genetics; Recombination; Stem cell; Gene","score_opus":0.007324581329542383,"score_gpt":0.2793270476621564,"score_spread":0.272002466332614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183228708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954454,0.0018620536,0.00026643672,0.00013240843,0.0004891544,0.000121858626,0.000008533709,0.000014269889,0.0016599171],"genre_scores_gemma":[0.9931841,0.0002174261,0.00014619042,0.000084711995,0.00006759925,0.000023820967,0.000105529994,0.000021451397,0.0061491514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898744,0.000035246056,0.00023445158,0.00043098783,0.00010149499,0.000210376],"domain_scores_gemma":[0.999415,0.000007439547,0.00008904493,0.00036823467,0.00006570519,0.00005462423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116910865,0.00012958245,0.00015483747,0.000032906442,0.000032387266,0.000018492688,0.000055138167,0.000113846436,0.000060622147],"category_scores_gemma":[0.000021466516,0.00014618199,0.000068225265,0.000119908625,0.000017626035,0.0000038452476,0.00006773405,0.000092875314,0.000004893347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062867666,0.00006831989,0.0006020129,0.000016137545,0.000027931033,0.00028308755,0.00013848415,0.00023272823,0.9896854,0.000002257899,0.0040307865,0.004906528],"study_design_scores_gemma":[0.00025177264,0.000057209356,0.0013750785,0.000016160617,0.000009234963,0.0002981747,0.00014392435,0.000036082198,0.988946,0.000042636028,0.008653896,0.00016982341],"about_ca_topic_score_codex":0.00001925815,"about_ca_topic_score_gemma":0.000026958038,"teacher_disagreement_score":0.0047367048,"about_ca_system_score_codex":0.000035163794,"about_ca_system_score_gemma":0.000097767894,"threshold_uncertainty_score":0.59611285},"labels":[],"label_agreement":null},{"id":"W3183618565","doi":"10.3390/ijms22158129","title":"Identification of Novel Insulin Resistance Related ceRNA Network in T2DM and Its Potential Editing by CRISPR/Cas9","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Competing endogenous RNA; CRISPR; microRNA; Cas9; Downregulation and upregulation; PI3K/AKT/mTOR pathway; Computational biology; Long non-coding RNA; Gene; Genetics; Signal transduction","score_opus":0.00612865600688129,"score_gpt":0.29084031778312797,"score_spread":0.2847116617762467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183618565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9521078,0.010967278,0.035677243,0.0005335064,0.00056494493,0.000026394413,0.00000825168,0.0000011871833,0.000113417904],"genre_scores_gemma":[0.99769294,0.0005710487,0.0014910037,0.000045517747,0.00012599668,6.189396e-7,0.000005987913,0.0000046822215,0.00006218578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999008,0.000029300596,0.0003957302,0.00014903268,0.00032004726,0.00009789863],"domain_scores_gemma":[0.999344,0.000010345518,0.00024459962,0.000055566812,0.0003125861,0.000032933884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046593865,0.00006128804,0.000088631445,0.00006206477,0.000025620842,0.000043289525,0.00023200111,0.00004954541,0.000004336443],"category_scores_gemma":[0.00020886588,0.000062411156,0.00004718386,0.00014076005,0.00005349776,0.000013610977,0.00006924649,0.00007664251,1.8698984e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016064412,0.00003446295,0.00037602932,0.0000050690173,0.00003183136,0.000030622934,0.000033442928,0.01867854,0.9798868,0.00024102669,0.00013275261,0.0005333783],"study_design_scores_gemma":[0.0006282558,0.00005178863,0.002635206,0.00009161184,0.00001096617,0.00016377268,0.00013469733,0.0031339277,0.9920587,0.00023921006,0.0007627025,0.00008913839],"about_ca_topic_score_codex":0.0000024593346,"about_ca_topic_score_gemma":0.0000069922244,"teacher_disagreement_score":0.045585185,"about_ca_system_score_codex":0.00001004122,"about_ca_system_score_gemma":0.000069737485,"threshold_uncertainty_score":0.2545053},"labels":[],"label_agreement":null},{"id":"W3183781959","doi":"10.1016/j.ymgme.2021.07.006","title":"Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing","year":2021,"lang":"en","type":"review","venue":"Molecular Genetics and Metabolism","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Dalhousie University","funders":"","keywords":"Genetic enhancement; Genome editing; Gene delivery; Fabry disease; Biology; Disease; Viral vector; Gene; Bioinformatics; Medicine; CRISPR; Genetics; Pathology; Recombinant DNA","score_opus":0.02729951381042701,"score_gpt":0.3370344338279793,"score_spread":0.3097349200175523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183781959","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013249181,0.99455404,0.0022910614,0.000057897254,0.00040444013,0.0010979666,0.00020674737,0.000019144043,0.000043752756],"genre_scores_gemma":[0.0008064876,0.99275607,0.003784466,0.00014407776,0.001022413,0.00046591708,0.0007381353,0.00018571754,0.00009673212],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99764496,0.00011038564,0.0004428505,0.0010900883,0.00021809537,0.0004936345],"domain_scores_gemma":[0.99866194,0.000021923739,0.0001660031,0.0007078796,0.00010982261,0.00033243225],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022112891,0.0006853221,0.0010572746,0.00010403179,0.00011000718,0.00009157404,0.00022755832,0.00043042217,0.000001984658],"category_scores_gemma":[0.00005362669,0.0006313609,0.00043326238,0.00006354967,0.00010402021,0.0000018968868,0.00023096519,0.00019476128,7.3814607e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000109626535,0.00004954705,0.0000011896583,0.0014612504,0.00036646985,0.000025946016,0.000024907245,0.000009614974,0.0016112397,0.0003166483,0.000076484,0.99604577],"study_design_scores_gemma":[0.0006561482,0.00012511363,0.000053267282,0.0006238645,0.0006238345,0.000044010027,0.000014844384,0.000022215292,0.0071703074,0.00007922954,0.9899151,0.0006720905],"about_ca_topic_score_codex":7.259016e-7,"about_ca_topic_score_gemma":0.0000010073122,"teacher_disagreement_score":0.99537367,"about_ca_system_score_codex":0.0000075937705,"about_ca_system_score_gemma":0.0001476032,"threshold_uncertainty_score":0.99961376},"labels":[],"label_agreement":null},{"id":"W3183866371","doi":"10.1016/j.tig.2021.06.016","title":"Retention of duplicated genes in evolution","year":2021,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":246,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University; University of Victoria; McGill University Health Centre","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institute for Advanced Research","keywords":"Neofunctionalization; Biology; Subfunctionalization; Functional divergence; Gene duplication; Gene; Genome; Genetics; Genome evolution; Human genome; Computational biology; Functional genomics; Genomics; Gene family; Evolutionary biology","score_opus":0.038174208270227404,"score_gpt":0.3846777893171786,"score_spread":0.3465035810469512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183866371","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015642291,0.9971143,0.00076105125,0.000002929283,0.00015788621,0.00012266445,0.000028133383,0.0000050982453,0.00024370436],"genre_scores_gemma":[0.0037214442,0.9940778,0.0008494499,0.0000015770939,0.00009820707,0.000038917813,0.0007997472,0.000040957337,0.00037192716],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985785,0.000085127955,0.0005998444,0.0004079692,0.000106883184,0.00022165733],"domain_scores_gemma":[0.99930084,0.000008701402,0.00014033422,0.0004738112,0.00004077275,0.00003555187],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014832312,0.00024789714,0.00066328904,0.00034688466,0.000008627999,0.000006393299,0.00019279175,0.00043225454,0.000020330783],"category_scores_gemma":[0.000021414746,0.00026235892,0.0002408015,0.000601559,0.000032267515,7.9878686e-7,0.000119424745,0.00014833131,0.0000018059557],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000278583,0.000056685247,0.00022530188,0.0012821569,0.000039407896,0.000005098569,0.000008952753,0.00070515566,0.002369934,0.000017600218,0.000121001875,0.99516594],"study_design_scores_gemma":[0.0004230515,0.00013385063,0.001395484,0.0026743256,0.00019844869,0.000031232696,0.000019288444,0.00020390363,0.0037171864,0.000012338514,0.9906509,0.0005399696],"about_ca_topic_score_codex":0.000014542167,"about_ca_topic_score_gemma":0.00012362898,"teacher_disagreement_score":0.9946259,"about_ca_system_score_codex":0.00004678454,"about_ca_system_score_gemma":0.00008717604,"threshold_uncertainty_score":0.99998283},"labels":[],"label_agreement":null},{"id":"W3183913095","doi":"10.1158/0008-5472.can-20-1518","title":"Modeling High-Grade Serous Ovarian Carcinoma Using a Combination of <i>In Vivo</i> Fallopian Tube Electroporation and CRISPR-Cas9–Mediated Genome Editing","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal General Hospital; Montreal Neurological Institute and Hospital; Montreal Children's Hospital; BC Cancer Agency; University of British Columbia; McGill University; McGill Genome Centre; McGill University Health Centre","funders":"Cancer Research Society","keywords":"Ovarian cancer; CRISPR; Ovarian carcinoma; Serous fluid; Cancer research; Biology; Cancer; BRCA mutation; Medicine; Pathology; Gene; Genetics","score_opus":0.03134777162215207,"score_gpt":0.3554774778367069,"score_spread":0.32412970621455484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183913095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98431265,0.0026073535,0.012627135,0.00017881197,0.000060379898,0.00015143782,0.000018719495,0.0000049819264,0.000038552298],"genre_scores_gemma":[0.9985778,0.00046864516,0.00056712015,0.000021177138,0.00018753888,0.000021750862,0.00009482711,0.00002183838,0.000039331448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988931,0.000092998256,0.00020072075,0.00029688384,0.00021174163,0.00030454592],"domain_scores_gemma":[0.9994492,0.0000127146905,0.000025213476,0.00016887786,0.0002804961,0.000063479194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032814321,0.00009223034,0.00013155055,0.00010946292,0.000073491654,0.000028716246,0.00007865114,0.00010597714,0.000011976007],"category_scores_gemma":[0.00008486208,0.00010742045,0.000023667215,0.0003023384,0.000037729173,0.0000073517635,0.000089180416,0.00017434436,1.9758075e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021953785,0.000025679796,0.002086518,0.00007299889,0.000013774409,0.000010053948,0.00013534576,0.023325404,0.97407216,0.000074806776,0.000016144308,0.00014515803],"study_design_scores_gemma":[0.00075953617,0.00009865371,0.0019317502,0.000033129712,0.000008167297,0.0000130954095,0.00032553426,0.09874357,0.8977079,0.00008537473,0.00016488021,0.00012840048],"about_ca_topic_score_codex":0.0010887317,"about_ca_topic_score_gemma":0.0007298579,"teacher_disagreement_score":0.07636426,"about_ca_system_score_codex":0.00007251534,"about_ca_system_score_gemma":0.00021292492,"threshold_uncertainty_score":0.4380479},"labels":[],"label_agreement":null},{"id":"W3184872681","doi":"10.2139/ssrn.3188424","title":"The Functional Genomic Circuitry of Human Glioblastoma Stem Cells","year":2018,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Hotchkiss Brain Institute; University of Calgary; University of Toronto","funders":"","keywords":"Glioblastoma; Stem cell; Computational biology; Biology; Cancer research; Genetics","score_opus":0.005072147459893888,"score_gpt":0.2438215929935317,"score_spread":0.2387494455336378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3184872681","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98021024,0.0035746044,0.015447912,0.000037453476,0.00030364416,0.000049312224,0.0000016802675,0.00000474643,0.00037039517],"genre_scores_gemma":[0.99650246,0.00088713114,0.000009753192,0.000019464895,0.0009097195,0.0000019159313,0.0000012269875,0.000017136237,0.0016512172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877965,0.000026711477,0.00019027753,0.00012692776,0.00011352949,0.0007628938],"domain_scores_gemma":[0.99960095,0.000007709814,0.00008188217,0.00018042991,0.00008692467,0.00004208993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049278204,0.000094560244,0.00007625424,0.00002804323,0.00024308286,0.000017870572,0.0001991999,0.00006402147,0.00001159633],"category_scores_gemma":[0.0000047520534,0.000073605726,0.000092785645,0.000049136994,0.000089480556,0.0000019011694,0.000043203567,0.0003220742,0.000009813698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043754495,0.0000129688415,0.0002559099,0.0000024033927,0.00010378743,2.3900205e-7,0.000017593315,0.000072404444,0.99071187,0.002720624,0.00032231002,0.0057361103],"study_design_scores_gemma":[0.0005390488,0.0016136973,0.001357703,0.000007130234,0.000028484503,0.00027556848,0.00048661095,0.00003848968,0.9793874,0.0050322306,0.0110676205,0.00016601145],"about_ca_topic_score_codex":0.0000034952745,"about_ca_topic_score_gemma":0.00020981554,"teacher_disagreement_score":0.016292183,"about_ca_system_score_codex":0.00006670248,"about_ca_system_score_gemma":0.0003927169,"threshold_uncertainty_score":0.30015546},"labels":[],"label_agreement":null},{"id":"W3185119339","doi":"10.1093/plphys/kiab356","title":"<i>GLABRA2</i>-based selection efficiently enriches Cas9-generated nonchimeric mutants in the T1 generation","year":2021,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Shandong Province; China Agricultural University; Institute of Genetics; Taishan Scholar Foundation of Shandong Province; Shandong University","keywords":"Mutant; CRISPR; Arabidopsis; Cas9; Mutagenesis; Biology; Genome editing; Gene; Genetics; Mutation; Arabidopsis thaliana; Phenotype; Computational biology","score_opus":0.010990284834019006,"score_gpt":0.2596841557884738,"score_spread":0.2486938709544548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185119339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951613,0.0006528125,0.003593804,0.00010913084,0.00024696204,0.00010335162,0.0000281691,0.0000115579305,0.00009290096],"genre_scores_gemma":[0.9973722,0.000082649996,0.00033211632,0.00057557964,0.00034386435,0.000028111868,0.001207204,0.000011947801,0.000046335168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907464,0.00014787872,0.00015888992,0.0003153396,0.00007570246,0.0002275549],"domain_scores_gemma":[0.9996695,0.000025765645,0.000037271086,0.00019337174,0.000047934376,0.000026152635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011254339,0.00013168447,0.00012461616,0.000038152644,0.00006946375,0.000015820373,0.00010593713,0.000110707864,0.000018570508],"category_scores_gemma":[0.000045654135,0.00010768094,0.000045114113,0.00023830934,0.000027348018,0.0000018899952,0.000025114963,0.00010011766,0.000007678966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026927546,0.00007203815,0.00030536563,0.000008441475,0.000014831477,0.000007890093,0.0000486223,0.03389109,0.96443695,0.000015010496,0.0008414668,0.00033136946],"study_design_scores_gemma":[0.00041035836,0.00012745641,0.010756748,0.000004276505,0.000012532273,0.000060525465,0.00004582686,0.026709983,0.95786166,0.0000067388373,0.0038498617,0.00015400429],"about_ca_topic_score_codex":0.000027028209,"about_ca_topic_score_gemma":0.00025561455,"teacher_disagreement_score":0.010451382,"about_ca_system_score_codex":0.000010762106,"about_ca_system_score_gemma":0.000082568455,"threshold_uncertainty_score":0.43911016},"labels":[],"label_agreement":null},{"id":"W3185590563","doi":"10.2139/ssrn.3887805","title":"Argonaute 1 Promotes Histone H3k9 Trimethylation to Facilitate Homologous Recombination","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Argonaute; Homologous recombination; Histone; Cell biology; Recombination; Chemistry; Genetics; Biology; Gene; RNA interference; RNA","score_opus":0.011170852355838229,"score_gpt":0.2886070397037788,"score_spread":0.2774361873479406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185590563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7948224,0.007637934,0.19579263,0.00080582505,0.00028579356,0.0001137876,0.000003836908,0.000014995143,0.00052283244],"genre_scores_gemma":[0.988846,0.0016299416,0.0011100444,0.00006832587,0.00017813746,0.0000082146225,0.000055464705,0.00001907019,0.008084804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985799,0.00006327208,0.00019860853,0.00023602674,0.000116854135,0.00080529787],"domain_scores_gemma":[0.99955237,0.000008927051,0.000047895814,0.00016870606,0.00014574075,0.00007636055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059490826,0.000118282966,0.00011137278,0.00006254732,0.00009560322,0.000024276567,0.00010620365,0.00008824281,0.000016397924],"category_scores_gemma":[0.00017657892,0.00012448753,0.00008608866,0.00013248525,0.000012795532,0.000004856158,0.00004001058,0.00038445502,0.000017658102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060866092,0.00008118032,0.00020366274,0.000009645066,0.0001252182,0.0000070332017,0.00016333729,0.0011895201,0.9230789,0.0015593667,0.00043359553,0.07308766],"study_design_scores_gemma":[0.0014602734,0.0015913959,0.0027358488,0.00002192673,0.00005720415,0.0013217919,0.0005634185,0.00020147815,0.91522264,0.03231821,0.0439716,0.00053421117],"about_ca_topic_score_codex":0.000009308029,"about_ca_topic_score_gemma":0.00016276605,"teacher_disagreement_score":0.19468258,"about_ca_system_score_codex":0.00019082092,"about_ca_system_score_gemma":0.0006826373,"threshold_uncertainty_score":0.5076454},"labels":[],"label_agreement":null},{"id":"W3185627173","doi":"10.3389/fbioe.2021.720534","title":"Editorial: Synthetic Nucleic Acids for Expanding Genetic Codes and Probing Living Cells","year":2021,"lang":"en","type":"editorial","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Synthetic biology; Nucleic acid; Genetic code; Computational biology; Biology; Genetics; DNA","score_opus":0.0028325603312903476,"score_gpt":0.23519436495751456,"score_spread":0.23236180462622422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185627173","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012393506,0.02118957,0.112369746,0.00004664355,0.85337174,0.00041370405,0.00010846738,0.00010137674,0.0000052344258],"genre_scores_gemma":[0.02766253,0.024108794,0.065683655,0.000011083045,0.88165563,0.00021292434,0.00021709834,0.0002254343,0.00022283982],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99795413,0.000026559897,0.0003771918,0.0009014072,0.00015882684,0.000581873],"domain_scores_gemma":[0.9992512,0.00009891888,0.000090179936,0.00040043303,0.00006711159,0.00009214884],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00028396692,0.00047350893,0.0005967522,0.00036342896,0.00009003266,0.000082270664,0.00025454795,0.002311927,8.5651516e-7],"category_scores_gemma":[0.0005013462,0.0005268223,0.00009309165,0.00016452966,0.00015557125,0.000004839649,0.00031082527,0.00057349744,2.180603e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032435208,0.000030184001,0.00012267452,0.00088406145,0.00015802318,0.00000763726,0.000083749284,0.0007986289,0.35389975,0.0000072652992,0.63822865,0.005746936],"study_design_scores_gemma":[0.00060726487,0.0003422938,0.000020151998,0.0006786583,0.00009834355,0.000015079716,0.00026280864,0.0025598004,0.09024636,0.00002841526,0.9042842,0.0008566561],"about_ca_topic_score_codex":0.000012323636,"about_ca_topic_score_gemma":0.000011916644,"teacher_disagreement_score":0.2660555,"about_ca_system_score_codex":0.000046777062,"about_ca_system_score_gemma":0.000079679055,"threshold_uncertainty_score":0.9997183},"labels":[],"label_agreement":null},{"id":"W3186286157","doi":"10.1186/s13578-021-00662-w","title":"Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy","year":2021,"lang":"en","type":"review","venue":"Cell & Bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Cystic Fibrosis Canada; Canadian Institutes of Health Research; Cystic Fibrosis Foundation Therapeutics","keywords":"CRISPR; Genetic enhancement; Cas9; Genome editing; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; Biology; Viral vector; Computational biology; Gene; Genetics","score_opus":0.014071238350403196,"score_gpt":0.3261055839795827,"score_spread":0.31203434562917953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186286157","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00796388,0.98944545,0.0014855206,0.000005167935,0.0006128235,0.0003306155,0.0000565877,0.000008915679,0.00009105208],"genre_scores_gemma":[0.033951126,0.96510994,0.0002707497,0.000023067381,0.00015260532,0.000025841131,0.00019090052,0.000037826725,0.00023791353],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99802935,0.000090890084,0.0005058356,0.0006980433,0.00027293895,0.00040294966],"domain_scores_gemma":[0.99912846,0.000015983425,0.00017202547,0.0005182146,0.000061196486,0.00010409188],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024686477,0.00035095637,0.0006921617,0.00015673683,0.000040663326,0.000034226323,0.0005645817,0.00035221523,0.000037286252],"category_scores_gemma":[0.000047337515,0.00031304988,0.00030945506,0.00045039857,0.00011767131,0.0000039878837,0.00022580489,0.00021138234,0.0000063985995],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001019729,0.00021740275,0.00010216403,0.0022467521,0.000052086732,0.0000750237,0.00007152088,0.000219501,0.88211364,0.0000024908502,0.00031477748,0.11457447],"study_design_scores_gemma":[0.0007517951,0.0003403516,0.00021192666,0.001422167,0.00014518276,0.00008863645,0.00007635125,0.00015139685,0.40917382,0.0000011437444,0.58652484,0.0011123817],"about_ca_topic_score_codex":0.000033347522,"about_ca_topic_score_gemma":0.0000093007,"teacher_disagreement_score":0.5862101,"about_ca_system_score_codex":0.000036142817,"about_ca_system_score_gemma":0.00035937387,"threshold_uncertainty_score":0.99993217},"labels":[],"label_agreement":null},{"id":"W3186356435","doi":"10.1038/s41598-021-94577-8","title":"Manipulation of the Tyrosinase gene permits improved CRISPR/Cas editing and neural imaging in cichlid fish","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Human Frontier Science Program; National Science Foundation","keywords":"CRISPR; Cichlid; Fish <Actinopterygii>; Genome editing; Tyrosinase; Gene; Computer science; Computational biology; Biology; Fishery; Genetics; Biochemistry; Enzyme","score_opus":0.0071520576338322496,"score_gpt":0.26710710077092775,"score_spread":0.2599550431370955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186356435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99618906,0.0007894956,0.0007544147,0.00013992515,0.0019278853,0.0000904011,0.0000024196104,0.0000043772925,0.000102009864],"genre_scores_gemma":[0.9992133,0.0000074500376,0.00025809227,0.000034015193,0.0000918465,0.000004023183,0.00004215795,0.0000086625105,0.00034050166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991189,0.000021295951,0.00023959266,0.00036099547,0.000112631395,0.00014657353],"domain_scores_gemma":[0.99939716,0.000003980407,0.00009209065,0.00037992766,0.00009374097,0.000033081964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029542585,0.00007496661,0.0000762669,0.000031088774,0.00008146271,0.000056848672,0.000050384195,0.000034998695,0.000004950653],"category_scores_gemma":[0.00016626256,0.000066525914,0.00004563751,0.0001440613,0.000063141684,0.000005562638,0.00013098281,0.000048692305,6.906985e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000015591513,0.000010563503,0.03876774,0.000017161634,0.000002207451,0.00003823639,0.00007295328,0.00052320486,0.9588665,0.0000014329916,0.00029044558,0.0014080403],"study_design_scores_gemma":[0.00009367307,0.000005203239,0.058999583,0.000016968033,0.0000070544047,0.00028411907,0.00010158015,0.003788372,0.93566984,0.000048773432,0.0009127447,0.00007209538],"about_ca_topic_score_codex":0.000015652473,"about_ca_topic_score_gemma":0.00011674878,"teacher_disagreement_score":0.02319662,"about_ca_system_score_codex":0.000007763987,"about_ca_system_score_gemma":0.000045079207,"threshold_uncertainty_score":0.27128482},"labels":[],"label_agreement":null},{"id":"W3187190363","doi":"10.1007/s00424-021-02566-7","title":"Correction to: Importance of evaluating protein glycosylation in pluripotent stem cell‑derived cardiomyocytes for research and clinical applications","year":2021,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Induced pluripotent stem cell; Glycosylation; Computer science; Computational biology; Information retrieval; Cell biology; Biology; Biochemistry; Embryonic stem cell","score_opus":0.051435618213019285,"score_gpt":0.40016479254189546,"score_spread":0.3487291743288762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3187190363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96742135,0.00069559197,0.031246513,0.00006424263,0.00013033107,0.00028561498,0.0000046531686,0.0000015569108,0.00015012722],"genre_scores_gemma":[0.9930422,0.00017169374,0.006402797,0.000014899797,0.00026124946,0.0000126550685,0.00001372847,0.000015425321,0.000065392276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986237,0.00042873205,0.0004833586,0.00021254171,0.00009703068,0.00015462037],"domain_scores_gemma":[0.99919385,0.00012016773,0.00016733712,0.00016146914,0.00028807225,0.00006907746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013564754,0.00007212884,0.00018722152,0.00007627781,0.000042578897,0.0000069098887,0.00010391336,0.000022917831,0.0000014352313],"category_scores_gemma":[0.00019207397,0.00007086527,0.0000853008,0.00010410573,0.000062238134,0.0000031850373,0.000088521076,0.00016573304,5.696472e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020713966,0.000054724886,0.00075946783,0.00004406927,0.000027039268,0.000002368904,0.00009794784,0.0031347892,0.9762329,0.00000695814,0.000085642205,0.019346949],"study_design_scores_gemma":[0.0013970108,0.0025834378,0.09551219,0.00010765346,0.000023928098,0.000030893836,0.00047405437,0.0017078787,0.8957296,0.0001959696,0.002092111,0.00014528063],"about_ca_topic_score_codex":0.000001742804,"about_ca_topic_score_gemma":0.0000074921645,"teacher_disagreement_score":0.09475272,"about_ca_system_score_codex":0.000011058195,"about_ca_system_score_gemma":0.0000867684,"threshold_uncertainty_score":0.2889802},"labels":[],"label_agreement":null},{"id":"W3187612437","doi":"10.7554/elife.68346.sa1","title":"Decision letter: Structurally distributed surface sites tune allosteric regulation","year":2021,"lang":"en","type":"peer-review","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Allosteric regulation; Saturated mutagenesis; Dihydrofolate reductase; Mutagenesis; Mutation; Small molecule; Surface protein; Computational biology; Biophysics; Directed evolution; Biology; Chemistry; Biochemistry; Enzyme; Gene","score_opus":0.012121089651871622,"score_gpt":0.3119049760421638,"score_spread":0.29978388639029213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3187612437","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.113518454,0.5261777,0.3018622,0.03732591,0.011658218,0.0023471727,0.0034332657,0.00024244258,0.003434639],"genre_scores_gemma":[0.08515313,0.06907649,0.04173699,0.012174506,0.004936935,0.000062910134,0.28300548,0.00040593997,0.5034476],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982497,0.00004704914,0.00043515844,0.0006547239,0.000317101,0.00029628616],"domain_scores_gemma":[0.99873143,0.000025222289,0.0001244669,0.0007516051,0.00026867003,0.00009861904],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014126717,0.0003959357,0.00044744296,0.000029070872,0.000052179086,0.000058315465,0.00027712787,0.0003920496,0.00072813197],"category_scores_gemma":[0.00015667004,0.00036080895,0.00024353256,0.00015859301,0.000026676147,0.0000026094572,0.0002881973,0.0001853255,0.000018856645],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009308407,0.000008962901,0.0000250251,0.0004931132,0.00006732566,0.00000602583,0.000002108446,0.00091780425,0.15414761,0.0000016045336,0.8407201,0.0036009704],"study_design_scores_gemma":[0.00021169292,0.00005904772,0.00063227146,0.0006059776,0.0000973225,0.000040439816,0.0000031344612,0.00016214851,0.04113587,0.000012236556,0.9565776,0.00046226048],"about_ca_topic_score_codex":0.000020148447,"about_ca_topic_score_gemma":0.00015343694,"teacher_disagreement_score":0.500013,"about_ca_system_score_codex":0.000027500857,"about_ca_system_score_gemma":0.000078392615,"threshold_uncertainty_score":0.99988437},"labels":[],"label_agreement":null},{"id":"W3187929447","doi":"10.3389/fgene.2021.733674","title":"Rapid CRISPR/Cas9 Editing of Genotype IX African Swine Fever Virus Circulating in Eastern and Central Africa","year":2021,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Consortium of International Agricultural Research Centers; International Development Research Centre","keywords":"CRISPR; Virology; African swine fever virus; Biology; Cas9; Virus; Genotype; Genome editing; Recombinant DNA; Virulence; Gene; Genetics","score_opus":0.009582255640640011,"score_gpt":0.24735571925112498,"score_spread":0.23777346361048496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3187929447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94252753,0.024368586,0.03172897,0.000051590392,0.0006002142,0.00012453448,0.000019354238,0.000006245921,0.00057295227],"genre_scores_gemma":[0.97641313,0.0011998983,0.02198069,0.000030627732,0.00022581982,0.000005704652,0.000029480268,0.000028252674,0.00008640025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875903,0.000051253228,0.00033410708,0.00034277607,0.00012894567,0.00038387178],"domain_scores_gemma":[0.99953216,0.00000915537,0.00006752743,0.00025479344,0.000053419564,0.00008292231],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011209574,0.00016345104,0.00023467332,0.000088680434,0.000024946505,0.000015469157,0.00011460389,0.00013937392,0.0000101575015],"category_scores_gemma":[0.000088481655,0.00019481358,0.00004536327,0.00020339614,0.00005430456,0.0000031167333,0.00014238332,0.00012482094,3.6602515e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041941224,0.000099062534,0.23011714,0.00014357199,0.000072050745,0.00006559331,0.001462218,0.010383428,0.71686876,0.00000657822,0.0010508056,0.039688878],"study_design_scores_gemma":[0.0022740795,0.0002674038,0.21857712,0.00014637834,0.000068670226,0.00005286859,0.0035398095,0.027350925,0.71071756,0.0001876589,0.035996456,0.0008210604],"about_ca_topic_score_codex":0.000022005357,"about_ca_topic_score_gemma":0.000080988866,"teacher_disagreement_score":0.038867816,"about_ca_system_score_codex":0.000023987228,"about_ca_system_score_gemma":0.000058997706,"threshold_uncertainty_score":0.7944267},"labels":[],"label_agreement":null},{"id":"W3188821865","doi":"10.1038/s41596-021-00591-5","title":"Identification of cancer-related mutations in human pluripotent stem cells using RNA-seq analysis","year":2021,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust","keywords":"Induced pluripotent stem cell; Computational biology; Biology; Gene; Genetics; Embryonic stem cell","score_opus":0.011146512655905622,"score_gpt":0.36956849378279105,"score_spread":0.35842198112688545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3188821865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98752815,0.00067983114,0.0043498515,0.000030264875,0.000052429183,0.0072747557,0.000027632741,0.000009601809,0.00004746577],"genre_scores_gemma":[0.99493235,0.00000908661,0.0005032602,0.000011871594,0.000028820925,0.0042539905,0.000046824953,0.000010666905,0.0002031487],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991959,0.000037476675,0.00031016095,0.00023432456,0.00011136894,0.00011077297],"domain_scores_gemma":[0.9994628,0.0000043446603,0.000108901346,0.00024881068,0.00014716825,0.00002800025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118972624,0.000085310145,0.00014113699,0.00010039766,0.000032345986,0.000015905267,0.00009160044,0.00021999038,0.000013860275],"category_scores_gemma":[0.000010144604,0.0000919258,0.000100082165,0.0005117403,0.000014223034,0.0000025306047,0.000035491765,0.0001478175,3.547031e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004714245,0.0000529673,0.0022333802,0.000054364722,0.00015371646,0.000002447693,0.00006381089,0.05273707,0.94424987,0.000027128473,0.000008122769,0.0004124257],"study_design_scores_gemma":[0.00031205444,0.000017486751,0.005210388,0.000032534546,0.00010652088,0.0000010004312,0.000037267266,0.0034274878,0.99028116,0.000027069882,0.00045223796,0.000094811774],"about_ca_topic_score_codex":0.000030992498,"about_ca_topic_score_gemma":0.00017272284,"teacher_disagreement_score":0.049309578,"about_ca_system_score_codex":0.000028653849,"about_ca_system_score_gemma":0.000070072914,"threshold_uncertainty_score":0.37486255},"labels":[],"label_agreement":null},{"id":"W3192232080","doi":"10.1101/2021.08.11.455876","title":"Whole genome analysis for 163 guide RNAs in Cas9 edited mice reveals minimal off-target activity","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"Common Fund; National Institutes of Health; Ontario Genomics; University of California, Davis; Genome Canada","keywords":"Biology; Genetics; Cas9; Mutagenesis; CRISPR; Genome; Genome editing; Null allele; Computational biology; Gene; Allele; Mutation","score_opus":0.009968616824890555,"score_gpt":0.26167411005344443,"score_spread":0.2517054932285539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3192232080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94453114,0.004818573,0.04831203,0.000114742485,0.0006217207,0.0006770933,0.0008599072,0.000056075638,0.00000873626],"genre_scores_gemma":[0.9814228,0.00035719687,0.016694399,0.0001190845,0.00090724137,0.00030202404,0.000028408671,0.00012026023,0.000048578877],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969405,0.00011727213,0.00061989203,0.0013921174,0.0002464694,0.0006837378],"domain_scores_gemma":[0.997638,0.000041701667,0.0002935903,0.0013231664,0.00046525442,0.00023827613],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006834106,0.00058516493,0.00082060683,0.0003775641,0.00008539198,0.00014472194,0.0005232713,0.00078975427,0.000023803803],"category_scores_gemma":[0.00037486118,0.0007168857,0.0004924936,0.00070260104,0.00005741317,0.000010622433,0.0005646599,0.00042594122,0.0000038489297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005571069,0.00012271655,0.005833266,0.00026575517,0.0007862451,0.000029958306,0.0000093543,0.0055435575,0.98696023,0.0000027537496,0.00038719716,0.00000324532],"study_design_scores_gemma":[0.0006508227,0.000081570826,0.17512311,0.000087829845,0.00045421525,4.0014847e-8,0.000008645948,0.0017059261,0.7862568,3.3357892e-7,0.03471279,0.0009178998],"about_ca_topic_score_codex":0.000080748854,"about_ca_topic_score_gemma":0.000078394,"teacher_disagreement_score":0.20070343,"about_ca_system_score_codex":0.00015200432,"about_ca_system_score_gemma":0.0004447735,"threshold_uncertainty_score":0.9995282},"labels":[],"label_agreement":null},{"id":"W3192620725","doi":"10.1038/s41467-021-25088-3","title":"Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"CIHR Skin Research Training Centre; National Cancer Institute; Alexander von Humboldt-Stiftung; Medical Research Council; Manchester Biomedical Research Centre; Cancer Research UK; University of California, San Francisco; Blood Cancer UK; Canadian Institutes of Health Research; National Institute of General Medical Sciences; National Institute for Health and Care Research; National Institutes of Health; U.S. Department of Health and Human Services; Government of Canada","keywords":"Embryonic stem cell; Stem cell; Promoter; Genome; Biology; Cell biology; Genetics; Computational biology; Gene; Gene expression","score_opus":0.013260796799638904,"score_gpt":0.2989350672914654,"score_spread":0.2856742704918265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3192620725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97922826,0.012649082,0.0023238917,0.004443258,0.00013717721,0.0005879464,0.000029515752,0.000025438427,0.0005754462],"genre_scores_gemma":[0.99403065,0.0005413658,0.0038149483,0.00029536136,0.00003343847,0.00008780926,0.00014444576,0.0000175913,0.0010343787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992673,0.00009404365,0.00013914499,0.0002382865,0.00007681376,0.0001844181],"domain_scores_gemma":[0.99865884,0.000012493284,0.000022144797,0.0011279628,0.00011098873,0.000067558314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015490357,0.00010921972,0.00010157113,0.000053592536,0.0000862762,0.000019048744,0.0004127415,0.0002626787,0.000006500789],"category_scores_gemma":[0.000038369715,0.00011774182,0.000056376437,0.00023273911,0.000025273877,0.0000029410396,0.00032184672,0.0005037344,0.00000928923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013554437,0.000059678958,0.00020027588,0.00002184641,0.000013031764,0.000002100484,0.0001797686,0.00031178189,0.9980443,0.00010073749,0.00031809122,0.00073480984],"study_design_scores_gemma":[0.00032844444,0.00007931911,0.0067971204,0.000029904577,0.000010614116,0.000017869943,0.00029141695,0.00021617323,0.7983225,0.000015886986,0.1936612,0.00022955728],"about_ca_topic_score_codex":0.000009742918,"about_ca_topic_score_gemma":0.0014004206,"teacher_disagreement_score":0.19972183,"about_ca_system_score_codex":0.00008176238,"about_ca_system_score_gemma":0.00008373177,"threshold_uncertainty_score":0.48013723},"labels":[],"label_agreement":null},{"id":"W3192875574","doi":"10.3389/fpls.2021.719148","title":"Multiplex Genome Editing in Yeast by CRISPR/Cas9 – A Potent and Agile Tool to Reconstruct Complex Metabolic Pathways","year":2021,"lang":"en","type":"review","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Trade, Industry and Energy","keywords":"CRISPR; Genome editing; Biology; Computational biology; Cas9; Yeast; Genome; Metabolic pathway; Genetic screen; Functional genomics; Gene; Saccharomyces cerevisiae; Genetics; Genomics; Mutant","score_opus":0.020872206727758306,"score_gpt":0.2951406179603775,"score_spread":0.2742684112326192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3192875574","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00303818,0.98897654,0.005758673,0.000008991932,0.00081252283,0.00046652928,0.000823518,0.000008151254,0.00010690726],"genre_scores_gemma":[0.0024133627,0.97932035,0.01742734,0.000058361784,0.00017163229,0.000068744426,0.00047047067,0.000027713257,0.000042009047],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979792,0.000053807536,0.0004389651,0.0008103737,0.00020516587,0.0005124552],"domain_scores_gemma":[0.99937975,0.000010284275,0.00009543403,0.00033173076,0.000031568386,0.00015123254],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049381325,0.00030192817,0.0007827774,0.0003002816,0.000074010095,0.000078028126,0.00043348773,0.00015733807,0.000004863745],"category_scores_gemma":[0.00017740102,0.00029533758,0.00009017312,0.0005212352,0.00014649253,0.000007798799,0.0003257525,0.00020706086,0.0000018445729],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006071693,0.00003826548,0.0004235246,0.00088913034,0.000037982747,0.00006256953,0.00015163787,0.00019251296,0.025113272,0.000015510155,0.00513042,0.9679391],"study_design_scores_gemma":[0.00019078603,0.000031018764,0.000365839,0.0009072592,0.000030444826,0.00015683596,0.00018015037,0.00036079655,0.00092532934,0.0000030020526,0.9963895,0.0004590121],"about_ca_topic_score_codex":0.000024748011,"about_ca_topic_score_gemma":0.000026061885,"teacher_disagreement_score":0.9912591,"about_ca_system_score_codex":0.000055140463,"about_ca_system_score_gemma":0.00021443934,"threshold_uncertainty_score":0.9999499},"labels":[],"label_agreement":null},{"id":"W3193345064","doi":"10.1111/nyas.14675","title":"Plant genome engineering from lab to field—a Keystone Symposia report","year":2021,"lang":"en","type":"review","venue":"Annals of the New York Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Genome; Genome editing; Attrition; Population; Biotechnology; Biology; Genetics; Medicine","score_opus":0.060735720950925595,"score_gpt":0.3777897518291813,"score_spread":0.3170540308782557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193345064","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001610019,0.99684596,0.00026856767,0.0006861316,0.00019986746,0.00019476854,0.00006444705,0.0000054956895,0.00012476073],"genre_scores_gemma":[0.0015059784,0.9960966,0.0012650348,0.0002351428,0.0004136515,0.00000833509,0.000024808603,0.000017514712,0.00043293647],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99849313,0.000031494936,0.00053082657,0.00042392607,0.00027759632,0.00024304766],"domain_scores_gemma":[0.9992951,0.00006012785,0.00026822902,0.00024634786,0.000023075221,0.00010708198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038553457,0.00022361813,0.00066094275,0.00008291214,0.000044872257,0.00001710038,0.0009425441,0.00027713628,0.000012850782],"category_scores_gemma":[0.00016943566,0.00016046705,0.00036295663,0.00038753822,0.00006110286,0.000002860543,0.0003647966,0.00017595282,0.0000017908905],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003579785,0.00016450294,0.00010057703,0.008431043,0.0021555156,0.000029593944,0.00069426117,0.017795824,0.27184755,0.0010932293,0.108696416,0.5889557],"study_design_scores_gemma":[0.000025711191,0.00005574446,0.00003910988,0.0021472375,0.00007191665,0.000038902133,0.000010727037,0.000005449851,0.07195444,0.000010841754,0.92545986,0.0001800842],"about_ca_topic_score_codex":0.00007158002,"about_ca_topic_score_gemma":0.000002164921,"teacher_disagreement_score":0.8167634,"about_ca_system_score_codex":0.0000037789107,"about_ca_system_score_gemma":0.00016268442,"threshold_uncertainty_score":0.65436566},"labels":[],"label_agreement":null},{"id":"W3193390573","doi":"10.34133/2021/9898769","title":"Embryo-Engineered Nonhuman Primate Models: Progress and Gap to Translational Medicine","year":2021,"lang":"en","type":"review","venue":"Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Cumming School of Medicine, University of Calgary; National Natural Science Foundation of China; University of Calgary","keywords":"Nonhuman primate; Translational medicine; Translational research; Mechanism (biology); Medicine; Neuroscience; Biology; Pathology; Evolutionary biology; Epistemology","score_opus":0.16050475598875122,"score_gpt":0.5097501975587536,"score_spread":0.34924544157000237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193390573","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000582836,0.99539095,0.0028084132,0.0001432455,0.00006981967,0.0006269954,0.000035718356,0.00001183319,0.0008547355],"genre_scores_gemma":[0.00039309493,0.99640614,0.0010202138,0.000009940968,0.0005046021,0.00018219033,0.00051954295,0.00006254304,0.00090174907],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981872,0.00013161088,0.00030127063,0.00054040947,0.0004205079,0.00041901728],"domain_scores_gemma":[0.9991137,0.000048542537,0.000024169327,0.00040384076,0.00019265596,0.00021710325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069426745,0.00024813288,0.00058965967,0.00021940276,0.00008303307,0.000039522485,0.00024688645,0.00025348747,0.00003660907],"category_scores_gemma":[0.000075102325,0.00021082554,0.0001111007,0.00029853702,0.00010348586,0.0000021671408,0.00018904755,0.00033593236,0.000007673698],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010629843,0.000043142027,0.0000019030022,0.010122394,0.0002325454,0.000027500739,0.00014075199,0.00022438892,0.0008890262,0.00074760907,0.004677656,0.98288244],"study_design_scores_gemma":[0.00018087991,0.00015327714,0.000004573842,0.0030741333,0.000059480953,0.00004940583,0.00002048565,0.00024246924,0.00015360532,0.0000430882,0.99576014,0.00025845083],"about_ca_topic_score_codex":0.0000053872905,"about_ca_topic_score_gemma":0.000006486702,"teacher_disagreement_score":0.9910825,"about_ca_system_score_codex":0.000018830147,"about_ca_system_score_gemma":0.00021464673,"threshold_uncertainty_score":0.8597216},"labels":[],"label_agreement":null},{"id":"W3194363567","doi":"10.1007/s11427-021-1949-9","title":"Transient expression of a TaGRF4-TaGIF1 complex stimulates wheat regeneration and improves genome editing","year":2021,"lang":"en","type":"article","venue":"Science China Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Genome editing; Biology; Genome; Regeneration (biology); Cultivar; Transformation (genetics); Transgene; Genetics; Biotechnology; Gene; Computational biology; Botany","score_opus":0.01269495860666505,"score_gpt":0.2973489078321888,"score_spread":0.2846539492255238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3194363567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902678,0.0017512355,0.006946228,0.000348332,0.00018669867,0.00007228602,0.000006435405,0.0000072552903,0.00041368947],"genre_scores_gemma":[0.99344707,0.00014740894,0.0061473213,0.00006116486,0.00014141858,0.0000027831022,0.000008570377,0.000003866581,0.00004039995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885017,0.000020265079,0.00017340443,0.00043562724,0.0002893062,0.0002312153],"domain_scores_gemma":[0.9995723,0.000008686892,0.000053639305,0.00016372821,0.000089977824,0.00011168868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004909494,0.00009481661,0.0001054495,0.00006439325,0.00031800958,0.00006220071,0.00021588388,0.000033951117,0.000010664768],"category_scores_gemma":[0.00019864742,0.00007831438,0.000030441537,0.000355009,0.000718932,0.000022789118,0.00012415036,0.000038392896,3.5017987e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000024713213,0.000012768727,0.00049591967,0.000015487052,0.0000012895946,4.2025033e-7,0.00024114345,0.00463941,0.9937179,0.000047346624,0.000031894026,0.00079396286],"study_design_scores_gemma":[0.00012571034,0.00013336744,0.029506197,0.000019075807,0.0000037795264,0.000009233187,0.00046275547,0.006367497,0.9628756,0.000057004097,0.0003356642,0.000104127575],"about_ca_topic_score_codex":0.000009598487,"about_ca_topic_score_gemma":0.000008206521,"teacher_disagreement_score":0.030842297,"about_ca_system_score_codex":0.0000052986693,"about_ca_system_score_gemma":0.00019192394,"threshold_uncertainty_score":0.31935677},"labels":[],"label_agreement":null},{"id":"W3194385641","doi":"10.3389/fbioe.2021.727584","title":"Decentralizing Cell-Free RNA Sensing With the Use of Low-Cost Cell Extracts","year":2021,"lang":"en","type":"article","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Agencia Nacional de Investigación y Desarrollo; Pontificia Universidad Católica de Chile; Comisión Nacional de Investigación Científica y Tecnológica; Danmarks Tekniske Universitet; Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias; International Center for Genetic Engineering and Biotechnology; University of Toronto; University of Minnesota","keywords":"RNA; Computer science; Biosensor; Nanotechnology; Gene; Computational biology; Biology; Materials science; Genetics","score_opus":0.006730671212553379,"score_gpt":0.20968104273652624,"score_spread":0.20295037152397286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3194385641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.701024,0.0051910616,0.29299018,0.00041406287,0.0002111372,0.00010920167,0.000009477057,0.000026199128,0.00002465679],"genre_scores_gemma":[0.93907493,0.00184366,0.05887819,0.000046456742,0.000032384603,0.0000029387945,0.000014608828,0.000024324221,0.000082511244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918824,0.00001529498,0.00015731702,0.00027718276,0.00006780037,0.00029415928],"domain_scores_gemma":[0.9994445,0.00001287532,0.00004240031,0.00042656728,0.000032171243,0.000041494754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006594363,0.00016171986,0.00018366089,0.00009765488,0.00003485202,0.000019734869,0.00014282763,0.0002542583,7.6421037e-7],"category_scores_gemma":[0.000042835913,0.0001318986,0.000035645393,0.00022506178,0.000109240595,0.0000045768043,0.00013122638,0.00019285476,1.5437901e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022705786,0.000026530393,0.0009179295,0.000093680195,0.000026391292,0.00003165536,0.00004400594,0.012981926,0.9778865,0.000012568328,0.0013974734,0.0065586274],"study_design_scores_gemma":[0.00046711508,0.00005459576,0.0004952008,0.00004504153,0.000015977297,0.000045267585,0.00023036788,0.004467681,0.97817636,0.0000049041328,0.01582033,0.00017717016],"about_ca_topic_score_codex":0.000011727986,"about_ca_topic_score_gemma":0.00002347555,"teacher_disagreement_score":0.23805091,"about_ca_system_score_codex":0.000010377451,"about_ca_system_score_gemma":0.00002758751,"threshold_uncertainty_score":0.5378669},"labels":[],"label_agreement":null},{"id":"W3194505801","doi":"10.1101/2021.08.20.457124","title":"Spacer2PAM: A computational framework for identification of functional PAM sequences for endogenous CRISPR systems","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Joint Genome Institute; Suncor Energy Incorporated; U.S. Department of Energy; David and Lucile Packard Foundation; National Science Foundation","keywords":"CRISPR; Trans-activating crRNA; Computational biology; CRISPR interference; Biology; Genome editing; Computer science; Genetics; Gene","score_opus":0.02318256366303384,"score_gpt":0.2729775222914282,"score_spread":0.24979495862839435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3194505801","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21898171,0.004085099,0.773644,0.000043537108,0.0015316644,0.00093786936,0.00073976355,0.00003540103,9.605458e-7],"genre_scores_gemma":[0.9620673,0.00015084537,0.036023617,0.000031750675,0.0008161458,0.00079839985,0.000030174382,0.00007605597,0.0000056862473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981269,0.000044466673,0.0005636681,0.0007332992,0.00023340443,0.00029825236],"domain_scores_gemma":[0.99777985,0.000092608585,0.00039684388,0.00059269986,0.0010370068,0.00010098235],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000413584,0.0003148045,0.00037235743,0.00010065596,0.000110843765,0.00012719427,0.00024747883,0.0005060919,0.0000047946087],"category_scores_gemma":[0.00037297915,0.00037109604,0.00024721032,0.00012951884,0.000066431785,0.0000062922777,0.00013586093,0.00017052317,0.000001136531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004742755,0.00007322827,0.00032988266,0.0010605246,0.00026473767,0.0000013607901,0.000010259319,0.093435265,0.9035356,0.0010805975,0.00015945846,0.0000016540997],"study_design_scores_gemma":[0.00050321606,0.0001358225,0.005170249,0.0002801707,0.00018301397,1.505583e-7,0.000035606394,0.01134984,0.98025376,0.00003210188,0.0014760254,0.0005800536],"about_ca_topic_score_codex":0.000013586932,"about_ca_topic_score_gemma":0.0000012571437,"teacher_disagreement_score":0.7430856,"about_ca_system_score_codex":0.0000568401,"about_ca_system_score_gemma":0.00053272804,"threshold_uncertainty_score":0.9998741},"labels":[],"label_agreement":null},{"id":"W3196310633","doi":"10.1101/2021.09.06.459125","title":"Synthetic reconstruction of the <i>hunchback</i> promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Agence Nationale de la Recherche; Infrastructures en Biologie Santé et Agronomie","keywords":"Drosophila embryogenesis; Morphogen; Transcription (linguistics); Biology; Transcription factor; Gap gene; Genetics; Cell biology; Cell fate determination; Embryo; Embryogenesis; Gene","score_opus":0.005795095077895329,"score_gpt":0.2038326350294991,"score_spread":0.19803753995160378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196310633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924152,0.0059349244,0.0005685155,0.00015546805,0.0003308379,0.00048266957,0.00009037114,0.000005659031,0.00001637221],"genre_scores_gemma":[0.9978686,0.0016088831,0.00035912078,0.000018029557,0.000080080135,0.000034716286,7.359052e-7,0.000027566439,0.0000022792603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987117,0.00015049879,0.0004297165,0.00035352458,0.0001877101,0.00016681846],"domain_scores_gemma":[0.99865216,0.000024785146,0.00026520307,0.00082272885,0.0002093345,0.000025790721],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043666025,0.0002216054,0.00028104082,0.00005189213,0.000040973995,0.000027894896,0.0003908882,0.00026872,0.0000053696303],"category_scores_gemma":[0.000087931265,0.00014899329,0.00014217592,0.00020581456,0.00020040106,0.000005864401,0.00017742814,0.0002851361,1.7182147e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019005458,0.00004950433,0.003445233,0.000340261,0.000061577324,4.5714629e-7,0.00007265931,0.0003032103,0.9954799,0.0001725468,0.0000039189604,0.00005172301],"study_design_scores_gemma":[0.00018361438,0.00004419507,0.034860637,0.0003318869,0.00007723273,2.3293912e-7,0.00015110137,0.0006845964,0.96324277,0.0000049144783,0.00026122213,0.00015760052],"about_ca_topic_score_codex":0.000028897102,"about_ca_topic_score_gemma":0.00004730995,"teacher_disagreement_score":0.03223714,"about_ca_system_score_codex":0.000019601915,"about_ca_system_score_gemma":0.00012923588,"threshold_uncertainty_score":0.607577},"labels":[],"label_agreement":null},{"id":"W3196896120","doi":"10.1038/s41596-021-00596-0","title":"Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline","year":2021,"lang":"en","type":"article","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; National Institutes of Health; Ontario Institute for Regenerative Medicine; National Science Foundation; U.S. Department of Health and Human Services; Government of Canada; Canadian Institutes of Health Research; Genome Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"CRISPR; Computer science; Guide RNA; Pipeline (software); Computational biology; Protocol (science); R package; Cas9; Data mining; Biology; Gene; Genetics; Programming language; Medicine","score_opus":0.0068566095752613946,"score_gpt":0.3312340295636992,"score_spread":0.3243774199884378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196896120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69012946,0.0067907777,0.20632981,0.0020084751,0.0008491946,0.08139929,0.00023991996,0.00012691604,0.012126125],"genre_scores_gemma":[0.99405473,0.000008077547,0.0010775563,0.00013017782,0.0002392099,0.0041586086,0.0000679215,0.000016313568,0.00024740517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992352,0.000033002223,0.0001514101,0.0002420064,0.0001867556,0.00015163682],"domain_scores_gemma":[0.9991964,0.000015306829,0.00006398124,0.00044397847,0.00024036363,0.00003994793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015318497,0.000116196265,0.00019533654,0.00004524118,0.00004714738,0.000017718248,0.00014765748,0.00018145678,0.000016068208],"category_scores_gemma":[0.00007839822,0.00007897137,0.00012386158,0.0004911755,0.000037151418,0.0000016541082,0.00008058579,0.00022921512,4.2158337e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067838054,0.00031259874,0.048022807,0.00020312548,0.0024046944,0.000040357634,0.00014759076,0.012301009,0.9245379,0.001700124,0.0038662432,0.00578517],"study_design_scores_gemma":[0.00091212644,0.00018874912,0.010536965,0.000040143706,0.00031297523,0.000007707288,0.00006660659,0.00038607136,0.92864305,0.000017570701,0.058710057,0.00017795696],"about_ca_topic_score_codex":0.00000828378,"about_ca_topic_score_gemma":0.00010960186,"teacher_disagreement_score":0.30392525,"about_ca_system_score_codex":0.0000051593306,"about_ca_system_score_gemma":0.00007224626,"threshold_uncertainty_score":0.32203588},"labels":[],"label_agreement":null},{"id":"W3197021219","doi":"10.1021/acs.analchem.1c03456","title":"Integrating Reverse Transcription Recombinase Polymerase Amplification with CRISPR Technology for the One-Tube Assay of RNA","year":2021,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Food Inspection Agency; Provincial Laboratory of Public Health; University of Alberta Hospital; University of Alberta","funders":"Li Ka Shing Institute of Virology, University of Alberta; China Scholarship Council; Canadian Institutes of Health Research; Alberta Innovates; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Recombinase Polymerase Amplification; Trans-activating crRNA; RNA; Molecular biology; Chemistry; Reverse transcriptase; Complementary DNA; CRISPR; Amplicon; Nucleic acid; DNA; RNase P; Cas9; Loop-mediated isothermal amplification; Biology; Gene; Polymerase chain reaction; Biochemistry","score_opus":0.012021296579035168,"score_gpt":0.28725625921673925,"score_spread":0.2752349626377041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197021219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6302065,0.0017351377,0.36362535,0.0028238236,0.00005970289,0.00020748263,0.00003800048,0.000026918042,0.0012770733],"genre_scores_gemma":[0.99627435,0.00009916223,0.0025876148,0.00007279907,0.000079085905,0.00003112521,0.00011356271,0.000015885635,0.000726387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992737,0.000011268966,0.00020253593,0.00026262528,0.000088460845,0.00016136195],"domain_scores_gemma":[0.9993074,0.00004132853,0.000051627667,0.00037735203,0.00017497397,0.000047345235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013686359,0.000113062146,0.00013657195,0.000015070849,0.000054687804,0.000012323191,0.00012696338,0.00015283191,0.000035101304],"category_scores_gemma":[0.00025771922,0.000090287416,0.00009145181,0.00016770652,0.00008968498,0.0000025133002,0.0000247973,0.00012104218,6.3435647e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048710106,0.000065383305,0.00014705036,0.000082276114,0.000086316286,0.0000012767069,0.00001573405,0.00010848218,0.9963278,0.00025477097,0.00030965736,0.0025524972],"study_design_scores_gemma":[0.0003811616,0.000061466155,0.00006887185,0.00003418195,0.000116507465,0.000017411947,0.0004614446,0.0018045941,0.9939514,0.000091640984,0.0028944756,0.00011685797],"about_ca_topic_score_codex":0.000007900095,"about_ca_topic_score_gemma":0.000009465177,"teacher_disagreement_score":0.3660679,"about_ca_system_score_codex":0.000011759517,"about_ca_system_score_gemma":0.00006876195,"threshold_uncertainty_score":0.36818138},"labels":[],"label_agreement":null},{"id":"W3197029269","doi":"10.1016/j.tibtech.2021.08.005","title":"The future of genome editing innovations in the EU","year":2021,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"European commission; Genome editing; Member states; Genome; European union; Computational biology; Commission; Political science; Biology; Business; International trade; Genetics; Gene; Law","score_opus":0.007212744733951079,"score_gpt":0.28874813694584556,"score_spread":0.2815353922118945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197029269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9599091,0.009874575,0.0011631286,0.026476627,0.00036994828,0.000068433226,0.000013699377,0.000016764747,0.0021077571],"genre_scores_gemma":[0.99846774,0.0006058567,0.00047333553,0.00011364238,0.00015599278,0.000011840531,0.00004071118,0.0000059478934,0.00012490051],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99946624,0.000024831319,0.00017177137,0.00013803071,0.0000462988,0.0001528021],"domain_scores_gemma":[0.9995905,0.000013518434,0.000032761043,0.00033435327,0.000023503682,0.0000053397093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016776714,0.00006365873,0.00007274027,0.000098206016,0.00003521552,0.000005466711,0.00022583331,0.00019986094,0.0000068403597],"category_scores_gemma":[0.00004560694,0.000044339267,0.000026815795,0.0006879039,0.00007669486,7.8146036e-7,0.000085762185,0.0001818061,5.770524e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000075948738,0.0000535353,0.0012714836,0.000008728484,0.000019467958,0.000013977783,0.00016123502,0.0004406208,0.8744397,0.020451155,0.00069059804,0.10244189],"study_design_scores_gemma":[0.0004738038,0.00010108177,0.032043472,0.0000096932,0.0000064622213,0.00006984292,0.0023658227,0.0001195178,0.47768408,0.00048466722,0.48649013,0.00015142598],"about_ca_topic_score_codex":0.0000048461206,"about_ca_topic_score_gemma":0.0005564119,"teacher_disagreement_score":0.48579955,"about_ca_system_score_codex":0.000005118687,"about_ca_system_score_gemma":0.000016314596,"threshold_uncertainty_score":0.18081029},"labels":[],"label_agreement":null},{"id":"W3197162173","doi":"10.1016/j.ymeth.2021.09.002","title":"A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis","year":2021,"lang":"en","type":"article","venue":"Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Québec Consortium for Drug Discovery; McGill University; U.S. Department of Defense","keywords":"CRISPR; Induced pluripotent stem cell; Genome editing; Biology; Mutation; Amyotrophic lateral sclerosis; Cas9; Genetics; Computational biology; Gene; Disease; Embryonic stem cell; Medicine","score_opus":0.03664849502571205,"score_gpt":0.3839700008920612,"score_spread":0.34732150586634913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197162173","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42904884,0.001299112,0.5691618,0.00023286814,0.00013067294,0.00009502544,0.000013967961,0.0000094636325,0.000008300425],"genre_scores_gemma":[0.38514292,0.00014502922,0.61382174,0.00020369732,0.00030214895,0.000058522237,0.00006998494,0.000023705286,0.00023225856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990729,0.00008242574,0.00017962183,0.00038718898,0.000049608512,0.00022826756],"domain_scores_gemma":[0.9994658,0.000022002389,0.000018428122,0.00026323603,0.0001259783,0.000104561324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002580918,0.0001356514,0.00015047473,0.000040408864,0.00008879535,0.000047459656,0.00007144901,0.00008787343,0.000008311587],"category_scores_gemma":[0.00022295999,0.00014391255,0.00007642989,0.00012605923,0.0000124885755,0.0000026468836,0.000088468194,0.00005529093,0.0000010632332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025113452,0.00001438009,0.000081119106,0.000017446564,0.000046064088,8.325264e-7,0.000073472744,0.0764213,0.8905992,0.000022321796,0.000109859815,0.03258892],"study_design_scores_gemma":[0.00043251333,0.000100653575,0.00029004688,0.000015209712,0.000057440142,0.000011155447,0.00003729793,0.17073034,0.8251537,0.00031186463,0.002635959,0.00022379024],"about_ca_topic_score_codex":0.000006402803,"about_ca_topic_score_gemma":0.000018041894,"teacher_disagreement_score":0.09430905,"about_ca_system_score_codex":0.000008586578,"about_ca_system_score_gemma":0.000040956795,"threshold_uncertainty_score":0.58685833},"labels":[],"label_agreement":null},{"id":"W3197279604","doi":"10.1089/hum.2021.152","title":"Preclinical Assessment of a Gene-Editing Approach in a Mouse Model of Mitochondrial Neurogastrointestinal Encephalomyopathy","year":2021,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"","keywords":"Thymidine phosphorylase; Biology; CRISPR; Transgene; Molecular biology; Cas9; Gene; Genetic enhancement; Genome editing; Genetics; Biochemistry; Enzyme","score_opus":0.036611345959657655,"score_gpt":0.35054599356576654,"score_spread":0.3139346476061089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197279604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.911656,0.00038078628,0.0875221,0.000006747226,0.000051718172,0.0001293022,0.000020837031,0.0000059768427,0.00022651901],"genre_scores_gemma":[0.9132552,0.00010940724,0.08620894,0.000024931405,0.00020837814,0.00002137041,0.00007035005,0.000021866445,0.000079520345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887276,0.00006655583,0.00040098853,0.00032425974,0.00014710572,0.00018834675],"domain_scores_gemma":[0.99940294,0.00001135499,0.00010558666,0.000338796,0.00009364383,0.000047666603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014946866,0.00013721778,0.000226548,0.000042997006,0.000022447994,0.000007272139,0.00016109025,0.0000760867,0.000009402162],"category_scores_gemma":[0.000027157485,0.00014481526,0.00012211435,0.0000649121,0.000054115193,0.0000024929664,0.000059723006,0.00011405224,1.1411558e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037153288,0.00025252375,0.0040732613,0.00001963975,0.000021651262,0.0000027051794,0.00010201113,0.043005455,0.9521045,0.00003747374,0.000011311051,0.0003323273],"study_design_scores_gemma":[0.0013873703,0.00037586375,0.0035792026,0.000012273545,0.0000066346515,0.000020622883,0.0000624728,0.017234528,0.97716165,0.00003348305,0.000014858474,0.00011106325],"about_ca_topic_score_codex":0.0000062792305,"about_ca_topic_score_gemma":0.000008342346,"teacher_disagreement_score":0.025770925,"about_ca_system_score_codex":0.000007796548,"about_ca_system_score_gemma":0.000113620874,"threshold_uncertainty_score":0.5905395},"labels":[],"label_agreement":null},{"id":"W3197338027","doi":"10.17504/protocols.io.bxvwpn7e","title":"FindingNemo Extraction 4: Circulomics Kit v1","year":2021,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Minion; Protocol (science); DNA extraction; DNA sequencer; Nanopore sequencing; Computer science; DNA sequencing; DNA; Computational biology; Homogeneous; Extraction (chemistry); Biology; Chromatography; Chemistry; Mathematics; Genetics; Polymerase chain reaction; Medicine; Gene","score_opus":0.011118322872635304,"score_gpt":0.3174426316785818,"score_spread":0.30632430880594647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197338027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77816135,0.0026284652,0.20594275,0.000121467114,0.0017184054,0.00020475137,0.000017845145,0.000045219727,0.011159755],"genre_scores_gemma":[0.9871542,0.0009789241,0.0063615926,0.00012379796,0.0006240613,0.000025169384,0.0007579314,0.00004021522,0.003934137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898314,0.000017336919,0.00019684227,0.00049656566,0.000104255756,0.00020183189],"domain_scores_gemma":[0.9992614,0.0000053955887,0.000057981655,0.000534947,0.000068130736,0.00007217066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000876128,0.00021369156,0.00016756696,0.000041424417,0.00002780748,0.0000770302,0.00016991129,0.00046807507,0.00012495571],"category_scores_gemma":[0.000044278244,0.000239124,0.00017646264,0.00003644466,0.000016441423,0.0000010089967,0.00042585618,0.00027353026,0.000011049244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010453411,0.00005111833,0.0005734837,0.00014757493,0.00013603024,0.0000129804375,0.000055793833,0.012780119,0.9748947,0.000030143188,0.005369843,0.005937747],"study_design_scores_gemma":[0.00033093715,0.000063278036,0.0039687296,0.00007511579,0.00008023833,0.00008136966,0.00026138185,0.0017666371,0.93955827,0.000081603794,0.052930422,0.0008019962],"about_ca_topic_score_codex":0.00003256308,"about_ca_topic_score_gemma":0.00005121301,"teacher_disagreement_score":0.20899282,"about_ca_system_score_codex":0.000021729433,"about_ca_system_score_gemma":0.000105626794,"threshold_uncertainty_score":0.97511935},"labels":[],"label_agreement":null},{"id":"W3198539112","doi":"10.1016/j.celrep.2021.109635","title":"Targeted genetic screening in bacteria with a Cas12k-guided transposase","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China; Simon Fraser University; Harvard Medical School","keywords":"Biology; Transposable element; Genome; Transposon mutagenesis; Computational biology; Genome engineering; Transposase; Mutagenesis; Genetics; Pseudomonas aeruginosa; Gene; Mutant; Genome editing; Bacteria","score_opus":0.006738469439765006,"score_gpt":0.24651434628826788,"score_spread":0.23977587684850288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198539112","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786129,0.001976776,0.018500907,0.000027803891,0.00009956007,0.000104145576,0.0000031279637,0.000013016227,0.0006617643],"genre_scores_gemma":[0.9850554,0.000106038395,0.013771947,0.00009101316,0.00007050859,0.000014875702,0.00016805653,0.000029069954,0.00069310534],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990099,0.000027501967,0.00025811163,0.00037925236,0.0000931304,0.00023208358],"domain_scores_gemma":[0.9994311,0.000004421471,0.00005074791,0.00037263965,0.000054661217,0.00008643505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009004145,0.00013895074,0.00013505192,0.00003210188,0.000029763858,0.000017732858,0.000041320884,0.00008913434,0.000048251502],"category_scores_gemma":[0.000025611052,0.0001378355,0.000051652754,0.00012149101,0.000018784685,0.0000018016627,0.000027187722,0.000084861495,0.0000014189175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017572558,0.00003633274,0.014765419,0.000031103875,0.000016073616,0.002986327,0.000068362,0.004779092,0.97648597,3.2706603e-7,0.0002435358,0.00056990515],"study_design_scores_gemma":[0.00041048706,0.000063056184,0.04949914,0.000023532291,0.000018324012,0.0011843772,0.00005147933,0.00012786765,0.9318948,0.000003819868,0.016500145,0.00022297984],"about_ca_topic_score_codex":0.000031315896,"about_ca_topic_score_gemma":0.00017518313,"teacher_disagreement_score":0.044591155,"about_ca_system_score_codex":0.0000055999158,"about_ca_system_score_gemma":0.00009799849,"threshold_uncertainty_score":0.56207687},"labels":[],"label_agreement":null},{"id":"W3198768601","doi":"10.1038/s41523-021-00322-9","title":"Clinical consequences of BRCA2 hypomorphism","year":2021,"lang":"en","type":"article","venue":"npj Breast Cancer","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"European Regional Development Fund; Instituto de Salud Carlos III; Institució Catalana de Recerca i Estudis Avançats; Centres de Recerca de Catalunya; Fundación Cellex; Agència de Gestió d'Ajuts Universitaris i de Recerca; Ministerio de Economía y Competitividad; Generalitat de Catalunya; European Commission; Fanconi Anemia Research Fund","keywords":"Fanconi anemia; RAD51; Missense mutation; Allele; Breast cancer; Cancer research; BRCA2 Protein; Biology; Ovarian cancer; DNA repair; Phenotype; Chemotherapy; DNA damage; Genetics; Cancer; Mutation; Germline mutation; DNA; Gene","score_opus":0.015509870257282326,"score_gpt":0.35314096221716623,"score_spread":0.3376310919598839,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198768601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862364,0.008528494,0.001792949,0.00082030625,0.0006026457,0.000053698357,0.00013651756,0.00000946901,0.0018195136],"genre_scores_gemma":[0.9972,0.0010790775,0.0006095671,0.00024352291,0.00033820843,0.000007648962,0.000020464839,0.000009854916,0.0004916651],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939775,0.000025159956,0.00018305708,0.00019805574,0.000075120995,0.00012082615],"domain_scores_gemma":[0.9995773,0.0000090811645,0.000039861385,0.00020184241,0.00011450451,0.000057414058],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008156343,0.00007269553,0.00012436586,0.000009533544,0.000015943271,0.000005151575,0.00007939806,0.00008663449,0.0002567536],"category_scores_gemma":[0.000026983555,0.00007061471,0.00008455742,0.000049288534,0.00011188754,0.0000010288333,0.000048537713,0.000054572367,0.0000039597066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037452493,0.000049935723,0.059298083,0.000028915592,0.00009288864,0.000011172919,0.000014760002,0.0002464471,0.8991287,0.00006438168,0.003040552,0.037986703],"study_design_scores_gemma":[0.00058556587,0.00005530734,0.1721253,0.000042423962,0.00003504995,0.00019321924,0.000044549277,0.00004437811,0.7817321,0.000054063956,0.04490075,0.00018731391],"about_ca_topic_score_codex":0.000050502204,"about_ca_topic_score_gemma":0.000044377168,"teacher_disagreement_score":0.11739662,"about_ca_system_score_codex":0.0000051716984,"about_ca_system_score_gemma":0.0001773012,"threshold_uncertainty_score":0.28795844},"labels":[],"label_agreement":null},{"id":"W3199566341","doi":"10.33774/chemrxiv-2021-7pdz9","title":"CRISPR-Click Enables Multi-Gene Editing with Modular Synthetic sgRNAs","year":2021,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Technische Universität München; Canada Research Chairs; Social Sciences and Humanities Research Council of Canada; Deutsche Forschungsgemeinschaft; University of Alberta","keywords":"Guide RNA; CRISPR; Cas9; Computational biology; Genome editing; Gene; Subgenomic mRNA; Biology; Computer science; Genetics","score_opus":0.010911339701671264,"score_gpt":0.28134054757344634,"score_spread":0.2704292078717751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199566341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.53581935,0.003879489,0.45791104,0.00011642496,0.0006414902,0.00034070527,0.000033368236,0.00007193938,0.0011861813],"genre_scores_gemma":[0.9448621,0.0008122701,0.051216975,0.00013602352,0.0008200885,0.00008395603,0.0005128119,0.0001048339,0.0014508944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979912,0.00004776682,0.00032379085,0.000957224,0.000224033,0.00045600493],"domain_scores_gemma":[0.9985427,0.000010770732,0.000104609084,0.0010003054,0.00018538602,0.00015619228],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016421442,0.00046356043,0.00037949355,0.0000736679,0.00008008178,0.00012491902,0.0003500132,0.0004573256,0.00009223125],"category_scores_gemma":[0.000089594185,0.00042037046,0.00020022599,0.00007643263,0.00006240561,0.0000022504494,0.0008023962,0.0003603321,0.000008067412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002260788,0.00012511488,0.00062572473,0.00033733982,0.00036397067,0.00007275829,0.00012394895,0.06354418,0.9327307,0.000009685866,0.0005084611,0.0015355462],"study_design_scores_gemma":[0.0004542077,0.00008869403,0.0005663862,0.00018168276,0.00010113666,0.00008190203,0.0003611388,0.004421737,0.9871988,0.000006308671,0.0058970097,0.0006409554],"about_ca_topic_score_codex":0.00015339276,"about_ca_topic_score_gemma":0.00014207304,"teacher_disagreement_score":0.4090428,"about_ca_system_score_codex":0.000022738814,"about_ca_system_score_gemma":0.00014795791,"threshold_uncertainty_score":0.9998248},"labels":[],"label_agreement":null},{"id":"W3200367469","doi":"10.1089/regen.2021.0025","title":"CRISPR Knock-in Designer: Automatic Oligonucleotide Design Software to Introduce Point Mutations by Gene Editing Methods","year":2021,"lang":"en","type":"article","venue":"Re GEN Open","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Sunnybrook Health Science Centre; Children's Hospital of Eastern Ontario","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Computer science; Cas9; Point mutation; Oligonucleotide; Context (archaeology); Biology; Genetics; Gene; Mutation","score_opus":0.022110814277653903,"score_gpt":0.3787794731610948,"score_spread":0.3566686588834409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200367469","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.050687123,0.0015636581,0.9459534,0.0006305807,0.00022646888,0.00054693874,0.000022160788,0.000031082545,0.00033856483],"genre_scores_gemma":[0.11553801,0.00006431106,0.8823421,0.0005972281,0.00028114277,0.00013088355,0.00016638632,0.00005769014,0.0008222418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984196,0.00026303736,0.00033119353,0.0005226665,0.00010724218,0.00035625728],"domain_scores_gemma":[0.99913573,0.00006331579,0.000051653944,0.0004960586,0.00010319374,0.0001500473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071689364,0.00019046814,0.00024032664,0.00005456244,0.00009458709,0.00012117546,0.00039781161,0.00010689882,0.00013543226],"category_scores_gemma":[0.00081320433,0.00021165452,0.00006335229,0.0002542855,0.000015969177,0.000009494,0.00044094198,0.000102933576,0.000029401832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010474016,0.000043018288,0.00011238357,0.000027394153,0.00004872251,0.000019295669,0.00026984344,0.013553862,0.9430515,0.0000050966814,0.019757105,0.023101296],"study_design_scores_gemma":[0.00036248952,0.00009040455,0.0005585167,0.000035428475,0.000028103075,0.000036491052,0.00035583554,0.0020397168,0.9845839,0.00008779633,0.011540044,0.00028126375],"about_ca_topic_score_codex":0.00004370965,"about_ca_topic_score_gemma":0.000045856304,"teacher_disagreement_score":0.06485088,"about_ca_system_score_codex":0.000041556963,"about_ca_system_score_gemma":0.00014604433,"threshold_uncertainty_score":0.8631021},"labels":[],"label_agreement":null},{"id":"W3201084854","doi":"10.1186/s12870-021-03138-8","title":"Development of a Csy4-processed guide RNA delivery system with soybean-infecting virus ALSV for genome editing","year":2021,"lang":"en","type":"article","venue":"BMC Plant Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Natural Science Foundation of Hebei Province; Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Iowa State University","keywords":"Biology; Genome editing; Guide RNA; Cas9; CRISPR; Genome; Nicotiana benthamiana; Computational biology; RNA editing; Genetics; Plant virus; Genome engineering; Gene; Virus; RNA","score_opus":0.014436264470276527,"score_gpt":0.2790246146358949,"score_spread":0.2645883501656184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201084854","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78915876,0.0010567982,0.20908721,0.0000048076477,0.00015180952,0.00015081621,0.000085166765,0.00002051266,0.00028414238],"genre_scores_gemma":[0.95248705,0.00002685114,0.046333604,0.000029412287,0.00029528036,0.000048348167,0.00070114963,0.000020728856,0.000057583406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998972,0.000025483007,0.00033008802,0.0003351001,0.000052014795,0.00028533893],"domain_scores_gemma":[0.9994663,0.00004634064,0.000122064004,0.00017052618,0.00014286986,0.000051906973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020698762,0.000156941,0.00023267845,0.000039521565,0.00007987376,0.000009975387,0.000110680594,0.0001392562,0.0000035741991],"category_scores_gemma":[0.00008321045,0.00013827057,0.000056629095,0.00006345767,0.000025113355,0.0000021282606,0.000081730046,0.000047800222,0.0000015003687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049597053,0.000018550989,0.0011065151,0.00030079452,0.0000896676,0.0000043688715,0.000087592656,0.00039192053,0.99709374,0.000052207426,0.000037460384,0.00076759345],"study_design_scores_gemma":[0.00055801665,0.0001190614,0.00065312,0.00006794206,0.000024255514,0.000095110714,0.00053923315,0.00032903635,0.98206484,0.0000015245174,0.01535186,0.00019599471],"about_ca_topic_score_codex":0.00001432514,"about_ca_topic_score_gemma":0.00036872822,"teacher_disagreement_score":0.1633283,"about_ca_system_score_codex":0.000020379797,"about_ca_system_score_gemma":0.0002596832,"threshold_uncertainty_score":0.563851},"labels":[],"label_agreement":null},{"id":"W3201184591","doi":"10.1139/bcb-2021-0340","title":"Emerging regulatory challenges of next-generation synthetic biology","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Biosafety; Biosecurity; Coronavirus disease 2019 (COVID-19); Preparedness; Synthetic biology; Pandemic; Process (computing); 2019-20 coronavirus outbreak; Biotechnology; Business; Biology; Political science; Risk analysis (engineering); Computer science; Computational biology; Ecology; Virology; Law; Infectious disease (medical specialty); Medicine; Outbreak","score_opus":0.014597946137955285,"score_gpt":0.2729822570595803,"score_spread":0.258384310921625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201184591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.933982,0.062062927,0.00082461775,0.00013635367,0.0001686699,0.00004076225,0.000014926917,0.000009858634,0.0027598762],"genre_scores_gemma":[0.99241847,0.0061861966,0.00056551315,0.00004163809,0.00028315317,0.000008461147,0.00019400903,0.000012756699,0.0002897774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991034,0.000045837034,0.00020422114,0.0004196651,0.00003079378,0.00019604244],"domain_scores_gemma":[0.9994671,0.0000135389255,0.00006407315,0.0003244218,0.00006739331,0.00006347118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010869301,0.0001487239,0.00017371046,0.000020726751,0.00004336752,0.0000055213072,0.000089407105,0.00029331495,0.000029450213],"category_scores_gemma":[0.000052381645,0.00015262062,0.000065325745,0.000042968524,0.00012216417,0.0000016687409,0.00010604576,0.00006510388,0.0000012264785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009120699,0.00003290099,0.00030023395,0.0000879638,0.000027143875,0.0000012520901,0.00002422488,0.00001692718,0.98725086,0.00045548385,0.000068459085,0.011725417],"study_design_scores_gemma":[0.00022248927,0.00008743614,0.00011795432,0.000009822671,0.000017372975,0.000023920978,0.00016046637,0.00008223575,0.9868936,0.00009748838,0.012122273,0.00016492435],"about_ca_topic_score_codex":0.000002577129,"about_ca_topic_score_gemma":0.0000029408047,"teacher_disagreement_score":0.058436487,"about_ca_system_score_codex":0.0000046907594,"about_ca_system_score_gemma":0.000052906034,"threshold_uncertainty_score":0.6223688},"labels":[],"label_agreement":null},{"id":"W3201187849","doi":"10.1101/2021.09.22.461415","title":"Peptide fusion improves prime editing efficiency","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Prime (order theory); Genome editing; Computer science; Computational biology; Peptide; Fusion; Biology; Combinatorial chemistry; Chemistry; Genome; Biochemistry; Gene; Mathematics; Combinatorics","score_opus":0.005907328310489834,"score_gpt":0.2335910919607953,"score_spread":0.22768376365030546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201187849","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96738243,0.004670293,0.025393931,0.0000663134,0.0018558917,0.00039923063,0.000054657292,0.00014241616,0.000034812725],"genre_scores_gemma":[0.989179,0.00047956276,0.0081343595,0.000112618225,0.0018403733,0.00008640831,0.0000035955036,0.00013815743,0.000025907795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99737555,0.00006826415,0.00046437548,0.001176276,0.00030732594,0.0006082393],"domain_scores_gemma":[0.99783546,0.000014583976,0.00023146268,0.0013188382,0.00036219755,0.00023745453],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003831619,0.0005451892,0.00040805238,0.00011749086,0.00014988067,0.00020128136,0.0005081338,0.0006448173,0.000024224897],"category_scores_gemma":[0.0003093079,0.00062247633,0.00024347502,0.00021413216,0.00007586466,0.000006939274,0.0010853554,0.0005366913,0.000014213774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000087498365,0.000073124014,0.00077936496,0.00020768662,0.00007668783,0.000023497849,0.0000074544705,0.000327072,0.9982645,0.000009853185,0.00021406419,0.000007923952],"study_design_scores_gemma":[0.00029388568,0.00007500169,0.016280765,0.0002309962,0.000066180975,5.7880325e-8,0.000010865807,0.00079998473,0.9754918,1.6385891e-7,0.0060547283,0.00069554115],"about_ca_topic_score_codex":0.000026084937,"about_ca_topic_score_gemma":0.0000036046847,"teacher_disagreement_score":0.022772692,"about_ca_system_score_codex":0.00006624082,"about_ca_system_score_gemma":0.00042479107,"threshold_uncertainty_score":0.99962264},"labels":[],"label_agreement":null},{"id":"W3201205181","doi":"10.1016/j.nmd.2021.07.119","title":"DMD – ANIMAL MODELS","year":2021,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Sanger sequencing; Genome editing; Biology; Reverse transcriptase; Stop codon; Exon; Primer (cosmetics); Plasmid; Genetics; Exon skipping; Duchenne muscular dystrophy; Coding region; Molecular biology; Population; CRISPR; Gene; Computational biology; Virology; Mutation; Medicine; Polymerase chain reaction; Chemistry; Alternative splicing","score_opus":0.006386999976338293,"score_gpt":0.259784377934933,"score_spread":0.2533973779585947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201205181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9512637,0.0034846256,0.037826374,0.00038433852,0.00022478445,0.00009640012,0.0000066230414,0.000034900095,0.0066782366],"genre_scores_gemma":[0.997651,0.00076096,0.0006922405,0.00029483577,0.00008845575,0.000010555822,0.000063428204,0.00003258087,0.00040595702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920636,0.000029338918,0.00010437332,0.00033520913,0.00011261166,0.00021211887],"domain_scores_gemma":[0.9995201,0.0000037192638,0.000014894328,0.00035803718,0.000035709792,0.00006754524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003945632,0.00012413638,0.00008832274,0.000019677816,0.000047212805,0.00002070742,0.000109716355,0.00007516211,0.000033814453],"category_scores_gemma":[0.000035161836,0.00013913563,0.00013094509,0.00009158668,0.000024725972,0.0000027902788,0.00009461205,0.0000712964,0.000010353265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001717393,0.00007160475,0.0006102288,0.000023944784,0.00004720329,0.00001632675,0.000036843336,0.0133064035,0.97844315,0.00033853535,0.0012617564,0.0058268146],"study_design_scores_gemma":[0.001685781,0.00048252082,0.01335994,0.000016721042,0.000075946664,0.00009424645,0.0002522483,0.007922966,0.6465913,0.0012758452,0.32731387,0.0009285837],"about_ca_topic_score_codex":0.000005048776,"about_ca_topic_score_gemma":0.000037714555,"teacher_disagreement_score":0.33185184,"about_ca_system_score_codex":0.000002857269,"about_ca_system_score_gemma":0.000038098155,"threshold_uncertainty_score":0.5673787},"labels":[],"label_agreement":null},{"id":"W3201541465","doi":"","title":"The Human Right to Science and the Regulation of Human Germline Engineering","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill Genome Centre","funders":"","keywords":"Germline; Corporate governance; Legislation; Political science; Human rights; Obstacle; Autonomy; CRISPR; Ideal (ethics); Engineering ethics; Law and economics; Engineering; Law; Biology; Sociology; Management; Genetics; Economics","score_opus":0.002273223495529147,"score_gpt":0.2519117664520196,"score_spread":0.2496385429564905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201541465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949923,0.0014991648,0.0028735984,0.00024495556,0.00006938241,0.000109507564,2.5661123e-7,0.000002636902,0.00020816115],"genre_scores_gemma":[0.9989808,0.00022871686,0.000031220745,0.000016123086,0.00012659485,0.0000021782023,8.668332e-7,0.000007718574,0.00060575886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990941,0.000012950342,0.00013600696,0.00010650185,0.00015127858,0.0004991372],"domain_scores_gemma":[0.9996502,0.00001050931,0.000044667293,0.00017626025,0.0000857076,0.00003268619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015762324,0.000064392705,0.00006693954,0.00003521322,0.0002258699,0.000031405016,0.0002145621,0.00002470884,0.0000027538],"category_scores_gemma":[0.00005060329,0.000038065496,0.000031881016,0.00009575796,0.00008491563,0.0000034403527,0.00005988966,0.00021574528,8.344508e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011950764,0.0000028918528,0.0001906451,0.0000025065463,0.000018886558,2.8898244e-8,0.000036616108,0.0009450056,0.96527666,0.032623056,0.000014170979,0.00087761064],"study_design_scores_gemma":[0.002575483,0.00094943994,0.024475528,0.000042230622,0.000046771172,0.00025868227,0.00051521615,0.002221436,0.9415606,0.015338409,0.011655292,0.00036090988],"about_ca_topic_score_codex":0.0000067717556,"about_ca_topic_score_gemma":0.000051908566,"teacher_disagreement_score":0.024284884,"about_ca_system_score_codex":0.000043213535,"about_ca_system_score_gemma":0.00015425417,"threshold_uncertainty_score":0.17372315},"labels":[],"label_agreement":null},{"id":"W3201785961","doi":"10.1007/978-1-0716-1740-3_8","title":"Exploring Candidate Human Synthetic Lethal Interactions Through siRNA and Quantitative Imaging-Based Approaches","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Identification (biology); CRISPR; Computational biology; Computer science; Pairwise comparison; Drug candidate; Artificial intelligence; Biology; Gene; Genetics","score_opus":0.10853526287953771,"score_gpt":0.452959814622651,"score_spread":0.34442455174311326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201785961","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2832324,0.0017565312,0.7141172,0.0001726439,0.00013858001,0.00007714494,0.0000066535445,0.000011215453,0.00048760735],"genre_scores_gemma":[0.5063007,0.00006035904,0.4933198,0.00011697026,0.000029590912,0.00006267416,0.00006316184,0.00002295679,0.000023778412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983863,0.0005316107,0.0002354417,0.0005236131,0.000042492877,0.00028050263],"domain_scores_gemma":[0.999449,0.0000774869,0.00004835565,0.00033336066,0.000042220785,0.000049576636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036901495,0.00018983264,0.00022481651,0.00007702102,0.00006686969,0.000020754629,0.000111460125,0.00007817505,0.000011777859],"category_scores_gemma":[0.00028843703,0.0002005849,0.00008083049,0.0001391371,0.00014294536,0.0000057190587,0.0001421438,0.00014584168,9.244801e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013151591,0.000039081766,0.0010188309,0.000022749638,0.000039575636,0.00003630045,0.0001515397,0.0010935939,0.99111474,0.0021940877,0.000003857746,0.004272491],"study_design_scores_gemma":[0.00038596065,0.000085344494,0.0005976793,0.000025903295,0.000024148629,0.00006124657,0.00048739766,0.0022594042,0.9920957,0.0010799762,0.0026450963,0.00025210672],"about_ca_topic_score_codex":0.00005947418,"about_ca_topic_score_gemma":0.000059789767,"teacher_disagreement_score":0.2230683,"about_ca_system_score_codex":0.000017951646,"about_ca_system_score_gemma":0.00004466281,"threshold_uncertainty_score":0.81796145},"labels":[],"label_agreement":null},{"id":"W3201934972","doi":"10.1007/978-1-0716-1740-3_7","title":"Identification of Synthetic Lethal Interactions Using High-Throughput, Arrayed CRISPR/Cas9-Based Platforms","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CRISPR; Computational biology; Cas9; False positive paradox; Scalability; Throughput; Computer science; Identification (biology); High-throughput screening; Synthetic lethality; DNA; Gene; Biology; DNA repair; Genetics; Artificial intelligence; Database","score_opus":0.022400510321548016,"score_gpt":0.4425861793562006,"score_spread":0.4201856690346526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201934972","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3502143,0.00045732365,0.64879775,0.000059022605,0.00032718494,0.000082000486,0.00001119934,0.0000071107174,0.000044117376],"genre_scores_gemma":[0.6173728,0.000020439411,0.38235444,0.000080844475,0.000038395614,0.000015422876,0.00007138474,0.00002085591,0.000025419411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984415,0.0002861497,0.00048467665,0.00046200654,0.000067842644,0.00025781806],"domain_scores_gemma":[0.99908,0.00006704132,0.00013024219,0.00054428354,0.000120984085,0.000057457648],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056324905,0.00017644456,0.0002727578,0.00012637838,0.000036197256,0.000010555218,0.00016928843,0.0002082569,0.000032409458],"category_scores_gemma":[0.00070952845,0.0001863005,0.00014027613,0.00024733768,0.00010269353,0.0000033494503,0.00010229023,0.00015718011,0.0000017741248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022436685,0.00007097047,0.00039527685,0.000031262618,0.000046990728,0.000012711833,0.000040521467,0.011614099,0.98472476,0.00044154088,0.0000061084365,0.0025933278],"study_design_scores_gemma":[0.00036720367,0.000070830996,0.00033001776,0.000021470909,0.000034292618,0.00004651035,0.000085953005,0.0053326767,0.9917636,0.0012660251,0.0004925318,0.0001889015],"about_ca_topic_score_codex":0.000041461724,"about_ca_topic_score_gemma":0.000020130754,"teacher_disagreement_score":0.2671585,"about_ca_system_score_codex":0.00002732786,"about_ca_system_score_gemma":0.00011635247,"threshold_uncertainty_score":0.7597114},"labels":[],"label_agreement":null},{"id":"W3202153515","doi":"10.17504/protocols.io.bxhxpj7n","title":"FindingNemo in OneDay: Ultra-Long ONT Library Preparation from Cell to Flowcell in One Day v1","year":2021,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Workflow; Isolation (microbiology); Protocol (science); Computer science; Nanopore sequencing; Nanotechnology; DNA sequencing; DNA; Biology; Materials science; Bioinformatics; Medicine; Database; Genetics","score_opus":0.009122532443662167,"score_gpt":0.2666016297411697,"score_spread":0.2574790972975075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202153515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.970048,0.0017207053,0.019805202,0.00014051389,0.00038074172,0.0005599653,0.000045921985,0.00002615954,0.007272809],"genre_scores_gemma":[0.98244166,0.0004949508,0.012173907,0.000225413,0.00024623057,0.000080342965,0.0020162018,0.00004942376,0.002271863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982362,0.00007629482,0.00042197056,0.000830894,0.0001386984,0.00029593965],"domain_scores_gemma":[0.99915737,0.000023603183,0.00005435469,0.0006323267,0.000020083926,0.00011223367],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013679187,0.00029177766,0.00032547422,0.00013964195,0.000012951917,0.000093184055,0.0002821022,0.0004967705,0.00018491542],"category_scores_gemma":[0.00003585466,0.0003429017,0.00010589092,0.00013046604,0.000009991634,0.0000054622988,0.000483374,0.00032963403,0.000015431937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007588766,0.00026745413,0.012096615,0.000140293,0.000039807757,0.00003877067,0.001079855,0.0737016,0.91000843,0.0000037870016,0.001414691,0.0011328186],"study_design_scores_gemma":[0.0004088947,0.000074204494,0.020645723,0.00017641795,0.000013303271,8.7769536e-7,0.0001485139,0.000920145,0.97559226,0.00003134578,0.0015354668,0.00045287106],"about_ca_topic_score_codex":0.00055326644,"about_ca_topic_score_gemma":0.0029647204,"teacher_disagreement_score":0.07278145,"about_ca_system_score_codex":0.000034620552,"about_ca_system_score_gemma":0.00016659206,"threshold_uncertainty_score":0.9999023},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"methods","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"protocol","about_ca_system":false,"about_ca_topic":false,"confidence":"medium"}],"label_agreement":"agree"},{"id":"W3202268534","doi":"10.1007/978-1-0716-1740-3_13","title":"Identification of Drug Resistance Genes Using a Pooled Lentiviral CRISPR/Cas9 Screening Approach","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Computational biology; Gene; Cas9; Genome editing; Genome; Genetics; Genetic screen; Phenotype","score_opus":0.02266510570125842,"score_gpt":0.4145856804927474,"score_spread":0.391920574791489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202268534","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17581098,0.009499835,0.81422204,0.000032354477,0.00013207081,0.00010935764,0.000007914388,0.0000075484236,0.00017788404],"genre_scores_gemma":[0.27101105,0.00011895304,0.72843075,0.00004601625,0.000045146808,0.000016356142,0.00006725253,0.000024583534,0.00023990145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979408,0.00071259966,0.00046354276,0.00052639795,0.00007803,0.0002786556],"domain_scores_gemma":[0.9991786,0.000029202782,0.00013493598,0.0004992389,0.00011839262,0.000039660285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093404826,0.00017463797,0.00028371363,0.00010747956,0.00003792581,0.000013034077,0.00020247615,0.00018709358,0.0000047896388],"category_scores_gemma":[0.0003013326,0.00019597074,0.00013799517,0.00028698068,0.000094678224,0.0000029574328,0.00017367328,0.00012016074,3.40938e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027608028,0.00004504758,0.0009418511,0.00005402813,0.000060676655,0.0000075281328,0.00005140619,0.0027750249,0.9913411,0.00037945496,0.000010272796,0.0043059797],"study_design_scores_gemma":[0.0003560061,0.000015311736,0.00032090265,0.000017541739,0.00003715028,0.00001709494,0.00013597542,0.0030700786,0.99423534,0.00043148382,0.0011657039,0.0001974021],"about_ca_topic_score_codex":0.000013745007,"about_ca_topic_score_gemma":0.000015619464,"teacher_disagreement_score":0.095200084,"about_ca_system_score_codex":0.0000131006955,"about_ca_system_score_gemma":0.000057784655,"threshold_uncertainty_score":0.7991455},"labels":[],"label_agreement":null},{"id":"W3202782153","doi":"10.3389/fmed.2021.698521","title":"Toward the Treatment of Inherited Diseases of the Retina Using CRISPR-Based Gene Editing","year":2021,"lang":"en","type":"review","venue":"Frontiers in Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Foundation Fighting Blindness","keywords":"CRISPR; Genome editing; Cas9; Genetic enhancement; RPE65; Gene; Biology; Computational biology; Genetics; Bioinformatics","score_opus":0.03576446635361226,"score_gpt":0.35521733684764517,"score_spread":0.3194528704940329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202782153","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00071303354,0.98790014,0.00976183,0.000084590756,0.0010654245,0.00040543446,0.00005136425,0.000002836356,0.000015320362],"genre_scores_gemma":[0.0015803837,0.99554026,0.0018916008,0.000029754929,0.0006778774,0.000031178923,0.00018345166,0.00003328616,0.00003222105],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998718,0.00015489174,0.00051048596,0.0002599391,0.00018195692,0.00017470725],"domain_scores_gemma":[0.9990587,0.00003304595,0.00026362203,0.00054416026,0.000060985585,0.000039457518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014028237,0.00025217852,0.0010263587,0.00007054745,0.000028401248,0.0000028229604,0.00026407366,0.00016004159,0.000008187058],"category_scores_gemma":[0.00017446106,0.00013449005,0.00031608646,0.00028934673,0.00020609016,6.932883e-7,0.000050675604,0.000098501514,4.0762625e-8],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068276684,0.00051984075,0.003855326,0.018260513,0.0014669538,0.000049354676,0.0009771261,0.0026430204,0.006057092,0.0000050393487,0.016597949,0.9494995],"study_design_scores_gemma":[0.00091334444,0.00037482416,0.00016838656,0.010636848,0.0018203472,0.000017760638,0.00064122793,0.00049479667,0.008265986,0.000004727988,0.9763908,0.00027097517],"about_ca_topic_score_codex":0.000031037016,"about_ca_topic_score_gemma":0.0000028250352,"teacher_disagreement_score":0.95979285,"about_ca_system_score_codex":0.000051336672,"about_ca_system_score_gemma":0.00017909874,"threshold_uncertainty_score":0.54843456},"labels":[],"label_agreement":null},{"id":"W3203111199","doi":"10.1016/j.jbc.2021.101251","title":"Structural and biochemical insights into CRISPR RNA processing by the Cas5c ribonuclease SMU1763 from Streptococcus mutans","year":2021,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Biological and Environmental Research; Natural Sciences and Engineering Research Council of Canada; U.S. Department of Energy","keywords":"Streptococcus mutans; CRISPR; Ribonuclease; RNA; Chemistry; Biology; Biochemistry; Microbiology; Computational biology; Genetics; Bacteria; Gene","score_opus":0.008727686904868132,"score_gpt":0.2706897064750677,"score_spread":0.26196201957019954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203111199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9736015,0.025225317,0.00064701005,0.0002611921,0.00006867621,0.000041195555,0.000019328045,0.0000063446564,0.00012939904],"genre_scores_gemma":[0.9980395,0.0005879866,0.00057254266,0.00017043414,0.0004975083,0.0000023952698,0.00007299196,0.000012386322,0.0000442504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897814,0.000035327193,0.00036248405,0.000287055,0.00014223537,0.00019474885],"domain_scores_gemma":[0.99923664,0.00003603075,0.00016438962,0.00020019921,0.00018914207,0.00017360275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008225933,0.00019657616,0.00023084045,0.000008043645,0.000099918485,0.000058042897,0.0002285929,0.00023061395,0.000060431612],"category_scores_gemma":[0.00029785564,0.0001222452,0.00011302231,0.00008789294,0.0001760042,0.0000055754713,0.00016147259,0.0003075303,5.5391195e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049996368,0.000027029242,0.00092455285,0.000022053076,0.00005065707,0.000047939353,0.00006411967,0.000020676305,0.9945136,6.9029227e-7,0.0011159693,0.0031627421],"study_design_scores_gemma":[0.00044532586,0.00007462499,0.0011785927,0.000037697984,0.0000327349,0.00020719867,0.00038062502,0.0001255071,0.99212414,0.00017516625,0.0050391383,0.00017923769],"about_ca_topic_score_codex":0.000006994909,"about_ca_topic_score_gemma":0.0000016687643,"teacher_disagreement_score":0.02463733,"about_ca_system_score_codex":0.000018334884,"about_ca_system_score_gemma":0.000082468614,"threshold_uncertainty_score":0.49850145},"labels":[],"label_agreement":null},{"id":"W3203517521","doi":"10.1007/978-1-0716-1740-3_9","title":"Mapping Genetic Interactions in Human Cancer Cells Using a One-Step tRNA-CRISPR System","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"CRISPR; Computational biology; Barcode; Pairwise comparison; Biology; Scalability; Genetic code; Genetic screen; Computer science; Genetics; Gene; Database; Artificial intelligence; Phenotype","score_opus":0.03504517912892666,"score_gpt":0.4543813950073448,"score_spread":0.4193362158784182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203517521","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35393634,0.0030213331,0.64224875,0.000026309355,0.0003787238,0.00013204827,0.000007176638,0.000010889606,0.00023845976],"genre_scores_gemma":[0.43002203,0.00012335283,0.56941295,0.000119108256,0.00011959216,0.00006413653,0.000026483081,0.00003809512,0.00007427031],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976962,0.00072387065,0.00047989335,0.00060642604,0.00006214337,0.00043146693],"domain_scores_gemma":[0.9992892,0.000032938216,0.00008423791,0.0004547974,0.00006877315,0.00007003564],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042031548,0.0002265288,0.0003537768,0.00021690056,0.000051195388,0.00001878971,0.0002001571,0.00020721667,0.000028245511],"category_scores_gemma":[0.000081292426,0.0002671263,0.00012612822,0.00036247633,0.00005429394,0.0000023539596,0.00020774767,0.0002520409,0.0000014745889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007636071,0.0000474077,0.002366468,0.00007400257,0.00005319951,0.00006517107,0.00007394481,0.008575351,0.9848066,0.00011112302,0.000007226938,0.0038118642],"study_design_scores_gemma":[0.0005020392,0.00003692625,0.0011310906,0.000120580815,0.00002026787,0.00005967793,0.0003346486,0.005149236,0.9891715,0.00007184714,0.0031044644,0.00029772037],"about_ca_topic_score_codex":0.00037688698,"about_ca_topic_score_gemma":0.00043785467,"teacher_disagreement_score":0.07608571,"about_ca_system_score_codex":0.000106736006,"about_ca_system_score_gemma":0.00009372994,"threshold_uncertainty_score":0.99997807},"labels":[],"label_agreement":null},{"id":"W3203740205","doi":"10.1038/s41598-021-98934-5","title":"Genomic background selection to reduce the mutation load after random mutagenesis","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Christian-Albrechts-Universität zu Kiel; Chinesisch-Deutsche Zentrum für Wissenschaftsförderung; Deutsche Forschungsgemeinschaft; University of Alberta","keywords":"Mutagenesis; Selection (genetic algorithm); Mutation; Genetics; Computational biology; Computer science; Biology; Gene; Artificial intelligence","score_opus":0.007735789272984202,"score_gpt":0.2767048886155344,"score_spread":0.2689690993425502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203740205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824686,0.0009976887,0.013239275,0.0001438021,0.0025723954,0.00017677808,0.0000013527932,0.000012587889,0.0003874979],"genre_scores_gemma":[0.99053824,0.000010056563,0.0007992154,0.00008528363,0.00021499945,0.00005049462,0.000047595007,0.000014153063,0.008239934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988527,0.00003572762,0.00021413848,0.00051461585,0.00019785574,0.00018492198],"domain_scores_gemma":[0.999198,0.000006319458,0.000048982467,0.00047579172,0.00020370113,0.00006721372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005506399,0.00009544135,0.0000775123,0.000029908233,0.00016066908,0.00016667772,0.000063783926,0.00005358441,0.00007957855],"category_scores_gemma":[0.00009790344,0.0000801369,0.00007809981,0.00024954215,0.000040338356,0.0000034877417,0.00007003815,0.000040648407,0.000022317074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028323742,0.000013309479,0.0004709191,0.00000683214,0.000018455925,0.00006679078,0.000116952746,0.0029961409,0.98946613,0.0000010627751,0.003720065,0.0030950205],"study_design_scores_gemma":[0.00014731294,0.000019203138,0.008758151,0.0000061888704,0.000020854413,0.0005516781,0.00010693118,0.00008333018,0.8858967,0.000068547015,0.10421941,0.0001217388],"about_ca_topic_score_codex":0.000011765652,"about_ca_topic_score_gemma":0.00012783399,"teacher_disagreement_score":0.10356947,"about_ca_system_score_codex":0.000031889726,"about_ca_system_score_gemma":0.00019092548,"threshold_uncertainty_score":0.32678878},"labels":[],"label_agreement":null},{"id":"W3203808599","doi":"10.1039/d1cs00098e","title":"The CRISPR–Cas toolbox for analytical and diagnostic assay development","year":2021,"lang":"en","type":"review","venue":"Chemical Society Reviews","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Brock University","funders":"National Natural Science Foundation of China","keywords":"Toolbox; CRISPR; Computational biology; Computer science; Biochemical engineering; Nanotechnology; Biology; Engineering; Genetics; Materials science; Programming language","score_opus":0.040465716331533425,"score_gpt":0.38768365924706416,"score_spread":0.34721794291553076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203808599","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000061019873,0.9899009,0.008952756,0.000052264866,0.00012362913,0.0008858793,0.000013679698,0.000007897011,0.00005690438],"genre_scores_gemma":[0.0000021412257,0.99323535,0.0046095583,0.00012274568,0.0004556815,0.00064260466,0.00043035563,0.000046138557,0.0004554221],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982407,0.00006701587,0.00066387793,0.00055427226,0.00010803715,0.0003660743],"domain_scores_gemma":[0.99872595,0.0005001553,0.00013495135,0.00043619052,0.000058365345,0.00014438099],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00071317074,0.00039629074,0.0010880847,0.00000518294,0.00014133412,0.0000723222,0.0002740271,0.00042080923,0.0000071104837],"category_scores_gemma":[0.0016913456,0.00025528576,0.0010716248,0.000101767764,0.000096252596,0.0000012578773,0.00021533696,0.00024252314,0.000007437212],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[6.654336e-7,0.000016433814,0.0000013600676,0.005876751,0.00019119983,4.7596583e-7,0.00001732979,1.1158316e-7,0.00016483413,0.000023975772,0.043361776,0.9503451],"study_design_scores_gemma":[0.000090384594,0.000013299478,5.9318495e-7,0.0018526054,0.000421768,0.00002019541,0.0000097997845,0.000009799871,0.0012186096,0.0000032146836,0.996029,0.00033070878],"about_ca_topic_score_codex":3.0746966e-7,"about_ca_topic_score_gemma":8.015597e-7,"teacher_disagreement_score":0.95266724,"about_ca_system_score_codex":0.000046297737,"about_ca_system_score_gemma":0.00016305597,"threshold_uncertainty_score":0.9999899},"labels":[],"label_agreement":null},{"id":"W3203868028","doi":"10.1038/s41434-021-00297-z","title":"CRISPR-SCReT (CRISPR-Stop Codon Read Through) method to control Cas9 expression for gene editing","year":2021,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Ataxia UK; Government of Canada; Ataxia Canada; National Ataxia Foundation","keywords":"CRISPR; Cas9; Biology; Gene; Exon; Genome editing; Stop codon; Plasmid; Molecular biology; Genetics; Nonsense mutation; Guide RNA; HEK 293 cells; Mutation; Missense mutation","score_opus":0.018984780308479828,"score_gpt":0.36636590565148996,"score_spread":0.34738112534301013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203868028","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.124065615,0.0073547103,0.8665589,0.00064514676,0.00053308863,0.0004672524,0.00013171017,0.00003773806,0.00020580471],"genre_scores_gemma":[0.5237672,0.002116158,0.462302,0.0047009024,0.004192407,0.000409454,0.0006291256,0.00018981862,0.0016929194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832416,0.0001121538,0.0003070052,0.00062106934,0.00016669682,0.00046889752],"domain_scores_gemma":[0.99894184,0.00004999111,0.00007259472,0.0005794507,0.00021620278,0.00013994609],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034485638,0.00027706422,0.000309237,0.000034493125,0.00014629205,0.000042920346,0.00021366775,0.00020434953,0.00007068556],"category_scores_gemma":[0.00009017633,0.0002711735,0.00019380442,0.000116846124,0.000018231978,0.0000056058243,0.00007884,0.00009766829,0.0000073752108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022489738,0.00004065822,0.000045713874,0.000017258857,0.000081287624,0.000008252675,0.0002611875,0.0022831287,0.97651625,0.00002035109,0.006000418,0.014500576],"study_design_scores_gemma":[0.0015510274,0.0002824741,0.00010541893,0.000016993385,0.000019437237,0.00003568906,0.00015270774,0.00023300285,0.81044054,0.000092545146,0.18680252,0.00026763996],"about_ca_topic_score_codex":0.00002442827,"about_ca_topic_score_gemma":0.000012814339,"teacher_disagreement_score":0.4042569,"about_ca_system_score_codex":0.000019817291,"about_ca_system_score_gemma":0.000069051275,"threshold_uncertainty_score":0.9999741},"labels":[],"label_agreement":null},{"id":"W3204408447","doi":"10.1136/medethics-2021-107720","title":"Heritable human genome editing is ‘currently not permitted’, but it is no longer ‘prohibited’: so says the ISSCR","year":2021,"lang":"en","type":"article","venue":"Journal of Medical Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Subject (documents); Law; Research ethics; Political science; Psychology; Computer science; Library science","score_opus":0.03088127317579206,"score_gpt":0.37243364614603036,"score_spread":0.3415523729702383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204408447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7070977,0.026985928,0.023431852,0.23245496,0.004834098,0.00025202872,0.0000989735,0.000027026343,0.004817397],"genre_scores_gemma":[0.94587445,0.0059526945,0.0010750996,0.03456636,0.008619006,0.0000034644063,0.000037777347,0.00005542486,0.0038157057],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99717987,0.00012660689,0.0005622091,0.00023133181,0.0015691713,0.00033082496],"domain_scores_gemma":[0.99830383,0.00011970523,0.00018911516,0.0003108819,0.0007983573,0.0002781038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023287863,0.00017568596,0.00024844473,0.000033657147,0.00025632035,0.00008981479,0.0004627143,0.000731428,0.0009110736],"category_scores_gemma":[0.0020835917,0.00013165158,0.00023935671,0.000104190774,0.00018599168,0.000006494947,0.00023969932,0.0022379726,0.000020394164],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041960855,0.00020205471,0.00025908832,0.00034883816,0.00036263542,0.0003427326,0.0045996225,0.00014118683,0.86978024,0.00012459431,0.120142914,0.003654136],"study_design_scores_gemma":[0.00091634697,0.00027042752,0.0005447142,0.0003189144,0.000099092606,0.00076145714,0.0018752925,0.00040914505,0.17487305,0.00008338431,0.81955147,0.000296725],"about_ca_topic_score_codex":0.0000150155765,"about_ca_topic_score_gemma":0.000030074223,"teacher_disagreement_score":0.69940853,"about_ca_system_score_codex":0.000020450329,"about_ca_system_score_gemma":0.0008156539,"threshold_uncertainty_score":0.9975617},"labels":[],"label_agreement":null},{"id":"W3204808521","doi":"","title":"Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges","year":2018,"lang":"en","type":"article","venue":"Kölner Universitäts PublikationsServer (Universität zu Köln)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Observatory; Reflection (computer programming); Key (lock); Global health; Genome; Political science; Data science; Computer science; Biology; Genetics; Computer security; Gene; Astronomy","score_opus":0.031721504672170574,"score_gpt":0.27031106201178656,"score_spread":0.23858955733961598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204808521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7424274,0.00083516166,0.24565369,0.0017265806,0.0008985784,0.00055221916,0.0002186362,0.00015854876,0.0075291772],"genre_scores_gemma":[0.9739672,0.00006466696,0.023428915,0.00018495115,0.0010611237,0.0000068718077,0.00019298316,0.000034807123,0.0010585012],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99832743,0.00005535867,0.00018204642,0.00065917725,0.00022260207,0.00055340666],"domain_scores_gemma":[0.99866575,0.000026063615,0.00012700942,0.0004710336,0.00047181407,0.00023835413],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022845427,0.0002946096,0.00022876548,0.00014321129,0.000559131,0.00006629199,0.00056652154,0.000262039,0.00008838601],"category_scores_gemma":[0.00007802805,0.00037286998,0.00020549352,0.0003842581,0.00029458318,0.00020360817,0.00029956247,0.00011399396,0.000017304992],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044991155,0.0004062509,0.00487804,0.00026264272,0.0017444817,0.000029965639,0.0037173505,0.0025450448,0.15159139,0.8091438,0.0125907995,0.0126403505],"study_design_scores_gemma":[0.0037329297,0.00086015806,0.021301458,0.000051929866,0.00029711833,0.00003057691,0.00825104,0.0011989144,0.009395232,0.0018670541,0.95178413,0.0012294422],"about_ca_topic_score_codex":0.000045034834,"about_ca_topic_score_gemma":0.0003465844,"teacher_disagreement_score":0.93919337,"about_ca_system_score_codex":0.00018641399,"about_ca_system_score_gemma":0.00014551036,"threshold_uncertainty_score":0.9998723},"labels":[],"label_agreement":null},{"id":"W3204910154","doi":"10.1101/2021.10.06.463037","title":"Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Toronto; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences; Medical Research Council; PHENOMIN; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale; European Molecular Biology Laboratory; Akademie Věd České Republiky; Ministry of Education, Culture, Sports, Science and Technology; Wellcome Trust; Agence Nationale de la Recherche; Ministero dell’Istruzione, dell’Università e della Ricerca; Genome Canada; Ontario Genomics; Centre National de la Recherche Scientifique","keywords":"Biology; CRISPR; Gene; Genetics; Allele; Null allele; Genome editing; Cas9; Germline; Computational biology; Gene knockout; Phenotype; Genome engineering; Function (biology)","score_opus":0.010772945985914918,"score_gpt":0.27016157654566786,"score_spread":0.2593886305597529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204910154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97038597,0.0050726216,0.023334099,0.000027025557,0.0005918144,0.00039475027,0.0001558562,0.00003483428,0.0000030120773],"genre_scores_gemma":[0.9887716,0.00055637,0.008724066,0.00002734627,0.0017249227,0.000053622058,0.0000061481846,0.00012851367,0.000007367952],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976005,0.000098464996,0.00072455395,0.00075685245,0.00035997859,0.00045965312],"domain_scores_gemma":[0.9976069,0.00003552476,0.00039594134,0.001262027,0.00049588527,0.00020373949],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028401433,0.0005559463,0.00056717807,0.00012494861,0.00007855207,0.00010155041,0.0006401285,0.00045471537,0.000047886624],"category_scores_gemma":[0.0002585395,0.0004928812,0.00040520477,0.00021614747,0.00009161783,0.000006585587,0.0005957368,0.00032923467,0.0000011695845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026753027,0.000100203906,0.0014287751,0.00015920463,0.00043220737,0.0000054190905,0.000019104544,0.05941434,0.9383365,0.000013203791,0.00005965672,0.0000046444943],"study_design_scores_gemma":[0.0003478602,0.00015047041,0.009839358,0.00013935614,0.00007935953,4.5353623e-8,0.000008744895,0.0025211845,0.98641706,8.9789076e-8,0.0000617356,0.0004347595],"about_ca_topic_score_codex":0.00009856839,"about_ca_topic_score_gemma":0.0000031198695,"teacher_disagreement_score":0.05689315,"about_ca_system_score_codex":0.000049598635,"about_ca_system_score_gemma":0.00059686933,"threshold_uncertainty_score":0.9997523},"labels":[],"label_agreement":null},{"id":"W3204910624","doi":"10.7717/peerj.12050","title":"Cross-reactivity and inclusivity analysis of CRISPR-based diagnostic assays of coronavirus SARS-CoV-2","year":2021,"lang":"en","type":"article","venue":"PeerJ","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Food Inspection Agency; York University","funders":"","keywords":"CRISPR; In silico; Coronavirus; Virology; Computational biology; Molecular diagnostics; Biology; Genome; Diagnostic test; Cross-reactivity; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Pandemic; Polymerase chain reaction; Coronavirus disease 2019 (COVID-19); Gene; Genetics; Disease; Medicine; Infectious disease (medical specialty); Cross reactions","score_opus":0.020139954453666096,"score_gpt":0.36912525816447167,"score_spread":0.34898530371080555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204910624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97359574,0.0011701814,0.024767969,0.00003919293,0.000049911436,0.000046919828,0.00011445896,0.000005001171,0.00021063711],"genre_scores_gemma":[0.99915427,0.000081295,0.0005356904,0.00005166942,0.000023040066,0.000004535749,0.00010783192,0.000009581819,0.000032079504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928474,0.00003713718,0.00018376578,0.00024092999,0.0001268872,0.00012653788],"domain_scores_gemma":[0.99930066,0.00011960649,0.0000728786,0.00031650945,0.00015797865,0.000032390435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017111283,0.00010423616,0.00026564905,0.000058342473,0.000028330518,0.000009561385,0.00007476848,0.00009162089,0.000014595912],"category_scores_gemma":[0.0005885415,0.00011154309,0.00013722118,0.00022296498,0.00008188116,0.0000024026951,0.00012686914,0.000053918164,4.0689002e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019884166,0.00008976879,0.1158858,0.000046494,0.00020624789,0.0000046867294,0.000023255265,0.0021604341,0.8794122,0.000009797924,0.000030357156,0.0021110747],"study_design_scores_gemma":[0.00022071674,0.000042171574,0.2932434,0.0000054383713,0.0002071204,0.0000016368076,0.0000068055815,0.0012226347,0.7041715,0.000008221123,0.0007920723,0.00007830777],"about_ca_topic_score_codex":0.00019022988,"about_ca_topic_score_gemma":0.00041594057,"teacher_disagreement_score":0.17735761,"about_ca_system_score_codex":0.0000071447216,"about_ca_system_score_gemma":0.00005774159,"threshold_uncertainty_score":0.45485955},"labels":[],"label_agreement":null},{"id":"W3206007153","doi":"10.1158/2159-8290.cd-21-0506","title":"Endogenous Retroelements and the Viral Mimicry Response in Cancer Therapy and Cellular Homeostasis","year":2021,"lang":"en","type":"review","venue":"Cancer Discovery","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Molecular mimicry; Epigenetics; Cancer; Mimicry; Histone; Immune system; Immunology; Genetics; DNA","score_opus":0.034396073384993835,"score_gpt":0.3369066096164206,"score_spread":0.30251053623142676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206007153","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.047283668,0.9517154,0.000058019967,0.00005032767,0.00022949676,0.0004371472,0.00020395701,0.0000031101042,0.000018878616],"genre_scores_gemma":[0.009019055,0.9898166,0.000015681091,0.00012111,0.00023351511,0.00035251444,0.00008936987,0.00004612088,0.0003060542],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99870294,0.00021690031,0.00027316684,0.00045836874,0.00009413466,0.00025450456],"domain_scores_gemma":[0.9994606,0.000046904494,0.00009076788,0.00033744777,0.000018108403,0.000046191693],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026378597,0.00029949,0.000650824,0.000053249452,0.000052433177,0.000073935145,0.00014760168,0.00017839168,0.000013225896],"category_scores_gemma":[0.000025378953,0.00021073736,0.00016393611,0.00010072278,0.000119721524,0.0000047540198,0.00016177038,0.00017902645,2.6272033e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007081722,0.0000378442,0.00016076626,0.0022907578,0.00054215884,0.00003504043,0.00020201712,0.000042121424,0.009344823,0.000017863047,0.0005140072,0.9861044],"study_design_scores_gemma":[0.0013036411,0.00008614477,0.00007472035,0.0016595218,0.00020074112,0.000021302403,0.000059970644,0.0000031428988,0.004673729,0.0000050615035,0.99153894,0.0003730752],"about_ca_topic_score_codex":0.00016971298,"about_ca_topic_score_gemma":0.00007193043,"teacher_disagreement_score":0.991025,"about_ca_system_score_codex":0.000053955755,"about_ca_system_score_gemma":0.0002825889,"threshold_uncertainty_score":0.859362},"labels":[],"label_agreement":null},{"id":"W3206048415","doi":"10.15252/msb.202110335","title":"High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing","year":2021,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Genome editing; Microbiome; Cas9; Computational biology; Genetics; Gene","score_opus":0.003842842298421581,"score_gpt":0.2490996015674397,"score_spread":0.24525675926901813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206048415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75789714,0.02201097,0.21827054,0.000053605054,0.0010923028,0.0002852572,0.00021361295,0.000031286054,0.00014530485],"genre_scores_gemma":[0.9966215,0.00020605783,0.0018295081,0.000045762106,0.00021647249,0.000024124487,0.00069524924,0.000045091503,0.000316251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982724,0.00013589313,0.00050411565,0.0005441571,0.00009935124,0.00044409206],"domain_scores_gemma":[0.99895,0.000019958617,0.0001383829,0.0005290424,0.00026663352,0.00009600729],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020496594,0.00027286194,0.00039079518,0.00008186277,0.00004981408,0.000024376586,0.00025652713,0.00035861676,0.000011482991],"category_scores_gemma":[0.00012341101,0.00028076116,0.00014794887,0.00021109554,0.00008746115,0.000003066958,0.00018290889,0.00011425723,0.0000059455633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012968339,0.00007539642,0.00013476818,0.00017318153,0.00011380873,0.000020488018,0.000027899407,0.0032499328,0.9939869,0.00019159817,0.0017024956,0.0003105514],"study_design_scores_gemma":[0.00045826257,0.00023390737,0.000022738064,0.000055127075,0.000037865993,0.000101831596,0.00009958201,0.00041243323,0.9829604,0.000007763527,0.015332497,0.0002776078],"about_ca_topic_score_codex":0.000058565023,"about_ca_topic_score_gemma":0.0000066009375,"teacher_disagreement_score":0.23872437,"about_ca_system_score_codex":0.000021206657,"about_ca_system_score_gemma":0.00009483186,"threshold_uncertainty_score":0.9999645},"labels":[],"label_agreement":null},{"id":"W3206969215","doi":"10.3389/fpls.2021.751891","title":"Efficient Multi-Sites Genome Editing and Plant Regeneration via Somatic Embryogenesis in Picea glauca","year":2021,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Natural Science Foundation of China","keywords":"Genome editing; Somatic embryogenesis; CRISPR; Biology; Genome; Cas9; Gene; Mutant; Genetics; Somatic cell; Computational biology; Embryogenesis","score_opus":0.006753624513737241,"score_gpt":0.23955697885274466,"score_spread":0.23280335433900742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206969215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90329075,0.002259791,0.09386658,0.000032481257,0.00040915393,0.00008549994,0.000027938444,0.0000055606665,0.000022236654],"genre_scores_gemma":[0.97446483,0.00015028665,0.025115618,0.000037592974,0.00007027876,0.00000982389,0.000082905986,0.000006917761,0.000061745945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989992,0.000023375926,0.00018368197,0.000379901,0.00014314607,0.0002707411],"domain_scores_gemma":[0.9997214,0.0000072994744,0.00003438773,0.00014648982,0.000025985215,0.00006442383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211661,0.00010321333,0.000118657,0.00013125484,0.00007022434,0.00003842506,0.00012003379,0.00005646596,0.0000013339321],"category_scores_gemma":[0.000094869756,0.00010633247,0.000017389199,0.0002675806,0.00008258996,0.0000046033947,0.0000951284,0.00005790037,6.2453483e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005558986,0.000026368754,0.031760555,0.000022926562,0.0000031172551,0.000021384749,0.00018512714,0.018834583,0.9485289,0.0000027031983,0.000051562027,0.0005572242],"study_design_scores_gemma":[0.0004667994,0.000033728305,0.07525298,0.000046692956,0.000006439202,0.00008896886,0.0004771241,0.37373656,0.5494357,0.000010749337,0.00021196673,0.00023226991],"about_ca_topic_score_codex":0.000012087442,"about_ca_topic_score_gemma":0.00013467972,"teacher_disagreement_score":0.39909318,"about_ca_system_score_codex":0.00003257392,"about_ca_system_score_gemma":0.000074241245,"threshold_uncertainty_score":0.4336112},"labels":[],"label_agreement":null},{"id":"W3208363900","doi":"10.1016/j.isci.2021.103380","title":"Automated design of CRISPR prime editors for 56,000 human pathogenic variants","year":2021,"lang":"en","type":"article","venue":"iScience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Sidney Kimmel Foundation; National Human Genome Research Institute; New York University; Canadian Institutes of Health Research; Defense Advanced Research Projects Agency; Melanoma Research Alliance; Brain and Behavior Research Foundation","keywords":"CRISPR; Genome editing; Computational biology; Palindrome; Cas9; Computer science; Prime (order theory); Human genome; Pipeline (software); Gene; Genome; Genetics; Biology; Programming language; Mathematics","score_opus":0.014058518735235781,"score_gpt":0.3165288039429584,"score_spread":0.3024702852077226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208363900","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.22523497,0.0013366434,0.77174395,0.000055114102,0.0011115816,0.00022966466,0.000040141804,0.0000466771,0.00020124327],"genre_scores_gemma":[0.9894688,0.000020419835,0.009763701,0.000029577006,0.00040810852,0.00001449332,0.000019226778,0.000010168712,0.0002654643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928755,0.00002068861,0.00014163798,0.0002599661,0.00010176917,0.00018836769],"domain_scores_gemma":[0.99954605,0.000012345938,0.000038447895,0.00024995557,0.000103737286,0.000049444247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018077117,0.00007999593,0.00009034734,0.000022110566,0.00006513156,0.000014426226,0.00016981039,0.000066437235,0.000013100437],"category_scores_gemma":[0.00009575492,0.00007970675,0.00006116903,0.00012160903,0.00006673805,0.0000028040747,0.00006491659,0.00002585653,0.000001494035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000043466957,0.000025476491,0.00006813493,0.000012124772,0.000009288613,0.0000018574744,0.00003549034,0.002154071,0.9944298,0.000023967197,0.0026986827,0.00053673494],"study_design_scores_gemma":[0.00020385203,0.00013337421,0.0022543683,0.000010187259,0.000011976494,0.0000085093525,0.000026152531,0.0055496064,0.9884503,0.000045717774,0.0031975245,0.00010846354],"about_ca_topic_score_codex":0.000003939896,"about_ca_topic_score_gemma":0.0000019560966,"teacher_disagreement_score":0.7642339,"about_ca_system_score_codex":0.0000054443317,"about_ca_system_score_gemma":0.00009381377,"threshold_uncertainty_score":0.32503468},"labels":[],"label_agreement":null},{"id":"W3208525937","doi":"10.3389/fpos.2021.731496","title":"The Geographies and Politics of Gene Editing: Framing Debates Across Seven Countries","year":2021,"lang":"en","type":"article","venue":"Frontiers in Political Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Framing (construction); Politics; Genome editing; Compromise; Sociology; Political science; Media studies; Social science; Biology; History; Law; Gene; Genetics; Genome","score_opus":0.0038440347315669863,"score_gpt":0.27877498600811007,"score_spread":0.2749309512765431,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208525937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815664,0.004776423,0.01246601,0.00048887037,0.00040206275,0.000040647345,0.000021347854,0.0000042470824,0.00023395909],"genre_scores_gemma":[0.9952709,0.00027161228,0.004152104,0.00010250626,0.000117899326,0.0000029723644,0.0000030527196,0.000004733666,0.000074208336],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889946,0.000014571708,0.0001439206,0.00020164625,0.00015462078,0.0005858044],"domain_scores_gemma":[0.99956626,0.000029625004,0.000019217612,0.00017171312,0.00009327463,0.000119934295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003174045,0.0000714839,0.00009004634,0.000027080154,0.00020882516,0.00005325893,0.00016869312,0.000050866598,6.4703545e-7],"category_scores_gemma":[0.000497827,0.000058156595,0.000024965,0.00018915863,0.0013298877,0.0000050090666,0.00014175173,0.000058997593,1.2293458e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028532704,0.00007973076,0.63810486,0.00015914123,0.00006769722,0.000025469315,0.0019228181,0.00036931146,0.26280028,0.090447135,0.0012691274,0.004725881],"study_design_scores_gemma":[0.00019518263,0.00004975576,0.07363328,0.000021217382,0.00000736096,0.000028311639,0.0054206224,0.0007772468,0.90662795,0.004647563,0.0084400745,0.000151432],"about_ca_topic_score_codex":0.000037379352,"about_ca_topic_score_gemma":0.000022559407,"teacher_disagreement_score":0.6438277,"about_ca_system_score_codex":0.000014238561,"about_ca_system_score_gemma":0.00010300012,"threshold_uncertainty_score":0.49000266},"labels":[],"label_agreement":null},{"id":"W3208539766","doi":"10.1016/j.celrep.2021.109909","title":"Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Epigenomics; Biology; Genetics; Induced pluripotent stem cell; Germline; Retrotransposon; DNA methylation; Embryonic stem cell; Genome; Gene; Transposable element","score_opus":0.026599244167459343,"score_gpt":0.2645176665325901,"score_spread":0.23791842236513078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208539766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99460185,0.00409483,0.0003595975,0.000020179874,0.00028558928,0.0001915208,0.0000020789653,0.000008244749,0.00043613583],"genre_scores_gemma":[0.9988262,0.00013993014,0.000049353963,0.000035802033,0.00009276413,0.000015555293,0.000015474825,0.000024672401,0.0008002606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898106,0.000040033265,0.00036023566,0.00031955825,0.00010868912,0.00019040277],"domain_scores_gemma":[0.99910146,0.0000033833908,0.00013986531,0.0006275797,0.00007099497,0.00005672403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012672039,0.00014231578,0.0001551117,0.00001617175,0.000075112664,0.000018797882,0.00010831757,0.000089485526,0.000013567093],"category_scores_gemma":[0.000004660136,0.00011055071,0.00012491662,0.000040016832,0.000040014493,0.00000128493,0.00017200281,0.00007822435,0.000002735018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000043195923,0.00004912448,0.00085880986,0.000054381067,0.00003938512,0.000039600556,0.0000837514,0.0013363214,0.996879,0.0000016939296,0.000088962595,0.0005646549],"study_design_scores_gemma":[0.00011062195,0.000076872886,0.0016207554,0.00001142343,0.00002495248,0.000066157416,0.00019835104,0.000014883556,0.9946959,0.0000098475375,0.0030360022,0.00013421924],"about_ca_topic_score_codex":0.000025234562,"about_ca_topic_score_gemma":0.000058884954,"teacher_disagreement_score":0.0042243632,"about_ca_system_score_codex":0.000022397033,"about_ca_system_score_gemma":0.000113080685,"threshold_uncertainty_score":0.45081273},"labels":[],"label_agreement":null},{"id":"W3208991043","doi":"10.5281/zenodo.3738361","title":"Generation of Knockout Cell Lines Using CRISPR-Cas9 Technology","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Computer science; Genetics; Biology; Gene","score_opus":0.05297389630115775,"score_gpt":0.29405869083927016,"score_spread":0.2410847945381124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208991043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82246745,0.0007738229,0.16987135,0.0006374105,0.00008910191,0.00026930196,0.000083236744,0.0001841531,0.0056241876],"genre_scores_gemma":[0.99712116,0.00008850007,0.0016414698,0.00007335333,0.00024471222,1.6291557e-8,0.00040701593,0.0003471088,0.00007665236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993045,0.000044206787,0.0001605005,0.00023983451,0.00009918629,0.00015179759],"domain_scores_gemma":[0.99942154,0.0000016233612,0.000053316213,0.00020737667,0.00024435393,0.00007176861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819455,0.00008444282,0.000087083026,0.0000752522,0.0002749443,0.000055167635,0.00031169588,0.00007900711,0.00042314833],"category_scores_gemma":[0.00018868063,0.00009438125,0.00003397552,0.00024228418,0.000056647612,0.000005361691,0.00042991142,0.00008336587,0.00012953125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000151489,0.000023993405,0.000005573675,0.00003917681,0.0000128383435,0.0000012939075,0.00012464478,0.0019370975,0.98059475,0.00007077826,0.00918454,0.007990177],"study_design_scores_gemma":[0.00021691405,0.00020426877,0.000024740872,0.000004610468,0.0000093064955,0.000017594351,0.000106538035,0.0043285177,0.6581186,0.000005430536,0.3368736,0.00008990676],"about_ca_topic_score_codex":0.0000023435234,"about_ca_topic_score_gemma":1.0154071e-7,"teacher_disagreement_score":0.32768905,"about_ca_system_score_codex":0.00001077068,"about_ca_system_score_gemma":0.0000033342696,"threshold_uncertainty_score":0.46331775},"labels":[],"label_agreement":null},{"id":"W3209141478","doi":"10.1186/s12967-021-03099-4","title":"Gene therapy for cystic fibrosis: new tools for precision medicine","year":2021,"lang":"en","type":"review","venue":"Journal of Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Institute of Human Development, Child and Youth Health; Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"Cystic fibrosis; Genetic enhancement; Medicine; Personalized medicine; Bioinformatics; Precision medicine; Disease; Computational biology; Intensive care medicine; Gene; Biology; Pathology; Internal medicine; Genetics","score_opus":0.062031633393245744,"score_gpt":0.4132152896408839,"score_spread":0.35118365624763814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209141478","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00000769298,0.70784104,0.2903291,0.000594112,0.0006446636,0.000516439,0.00005125208,0.000002046879,0.000013641772],"genre_scores_gemma":[0.00004602077,0.9704786,0.020547526,0.000098561155,0.00758209,0.000035816487,0.0009081027,0.00005258508,0.00025072225],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99814194,0.000045644094,0.0010581557,0.00024860943,0.0003246006,0.00018106328],"domain_scores_gemma":[0.998221,0.0006185518,0.0004350277,0.0001954375,0.00036907967,0.00016091688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006330409,0.00029989847,0.0012392916,0.00014994596,0.000043252694,0.000011961354,0.00024020705,0.00026757573,0.00006183052],"category_scores_gemma":[0.0005931008,0.0001983652,0.00057069754,0.00011765745,0.000045153774,0.000006371412,0.000008820286,0.00015110418,3.0059877e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016769794,0.000023226043,3.6591194e-7,0.0014888628,0.0004191685,0.0000022319966,0.000059631704,0.0001796534,0.004890448,0.000027592494,0.014537352,0.9782038],"study_design_scores_gemma":[0.0026727023,0.001745241,0.000006353788,0.008156156,0.00080552616,0.00021464327,0.000015543226,0.00001750862,0.00062400574,0.00018438799,0.985376,0.00018194884],"about_ca_topic_score_codex":0.0000012698156,"about_ca_topic_score_gemma":0.0000015590634,"teacher_disagreement_score":0.9780218,"about_ca_system_score_codex":0.00001593738,"about_ca_system_score_gemma":0.00047528712,"threshold_uncertainty_score":0.80890983},"labels":[],"label_agreement":null},{"id":"W3209482382","doi":"10.3389/frym.2021.600133","title":"CRISPR: A New Way for Scientists to Edit DNA","year":2021,"lang":"en","type":"article","venue":"Frontiers for Young Minds","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; PROTEO; Université Laval; University of Ottawa","funders":"","keywords":"CRISPR; Cas9; Computational biology; DNA; Biology; Human welfare; Computer science; Gene; Genetics; Political science; Welfare; Law","score_opus":0.007618934234051389,"score_gpt":0.2924289082096401,"score_spread":0.2848099739755887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209482382","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.050768394,0.0017246945,0.94208986,0.0004597554,0.004012196,0.0003824004,0.00010800319,0.000013940129,0.00044075868],"genre_scores_gemma":[0.4920385,0.00006838268,0.38171497,0.0007559958,0.0047965935,0.00037093431,0.0011845836,0.00013695957,0.1189331],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990244,0.000005358354,0.00014387265,0.00039336173,0.000093870476,0.00033913055],"domain_scores_gemma":[0.999388,0.0000054236093,0.000023382136,0.00028948727,0.00011679083,0.00017695993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010662818,0.0001342558,0.00014133967,0.000047352903,0.0000872748,0.00004745616,0.00015710648,0.00010970892,0.000011715231],"category_scores_gemma":[0.00014839598,0.00014852063,0.00015752162,0.00010153003,0.000017915654,0.000002802356,0.00006278438,0.000031751606,0.000004048785],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050527786,0.000017655637,0.00029217752,0.000025834035,0.00005013536,0.0000014519557,0.00008510027,0.00011690978,0.3007126,0.00003506383,0.69148785,0.0071246717],"study_design_scores_gemma":[0.00049361296,0.00013186653,0.00030046128,0.0000069501716,0.000026711215,0.000008682226,0.00008248113,0.00018778724,0.45390505,0.00008410568,0.5446218,0.00015046899],"about_ca_topic_score_codex":0.0000051291645,"about_ca_topic_score_gemma":0.00004875312,"teacher_disagreement_score":0.5603749,"about_ca_system_score_codex":0.00002012006,"about_ca_system_score_gemma":0.00011402503,"threshold_uncertainty_score":0.6056496},"labels":[],"label_agreement":null},{"id":"W3209506262","doi":"10.1016/j.celrep.2021.109930","title":"Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Center for Complementary and Integrative Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Damon Runyon Cancer Research Foundation; Canadian Institutes of Health Research; Burroughs Wellcome Fund; University of Waterloo; Searle Scholars Program; University of California, San Francisco","keywords":"CRISPR; Microbiome; Biology; Strain (injury); Genetics; Cas9; Gut microbiome; Computational biology; Gene","score_opus":0.009678701032878084,"score_gpt":0.2621356286218366,"score_spread":0.2524569275889585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209506262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96718407,0.007024323,0.024787158,0.00011127077,0.00017100284,0.00024280297,0.000023962006,0.000006690125,0.00044873758],"genre_scores_gemma":[0.9962895,0.00067178195,0.00215228,0.00010902609,0.000120444165,0.000031899606,0.00028080802,0.00001607031,0.0003281914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992729,0.000020985535,0.00020197456,0.00029401208,0.000046393834,0.00016373514],"domain_scores_gemma":[0.9995731,0.000011816529,0.000045712095,0.00028840918,0.000048701502,0.00003227635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016938012,0.00009649558,0.0000851945,0.000025310834,0.000061924504,0.00003316364,0.000051382467,0.00007778738,0.000015015134],"category_scores_gemma":[0.000019768844,0.00008943917,0.000058766225,0.000058315964,0.000025585556,0.0000016999645,0.000037916823,0.00005235297,0.0000011609128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005250891,0.000031400625,0.00029184678,0.000023314704,0.0000069782877,0.00008003061,0.000086043074,0.00019810116,0.9963122,0.000012273648,0.0021753288,0.0007772143],"study_design_scores_gemma":[0.0005008767,0.00007372111,0.013738945,0.00001178182,0.000025164874,0.0008310231,0.000478899,0.00008936282,0.6824555,0.00010958667,0.30144686,0.00023829711],"about_ca_topic_score_codex":0.0000049361374,"about_ca_topic_score_gemma":0.00003051356,"teacher_disagreement_score":0.31385675,"about_ca_system_score_codex":0.000010348654,"about_ca_system_score_gemma":0.00003652452,"threshold_uncertainty_score":0.36472234},"labels":[],"label_agreement":null},{"id":"W3210034971","doi":"10.1007/978-1-0716-1720-5_1","title":"A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9","year":2021,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"CRISPR; Induced pluripotent stem cell; Biology; Computational biology; Gene; Human Induced Pluripotent Stem Cells; Cas9; Genome editing; Genetics; Genome; Scale (ratio); Embryonic stem cell; Geography; Cartography","score_opus":0.01482567224147151,"score_gpt":0.40220267410295935,"score_spread":0.3873770018614878,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210034971","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20016721,0.0019417473,0.797272,0.000093366645,0.00008983351,0.00023748686,0.000065418695,0.000009946758,0.00012296415],"genre_scores_gemma":[0.06281838,0.000046882164,0.9361587,0.00030546213,0.000055656186,0.000038140086,0.00015685473,0.000050731454,0.00036918046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99711454,0.0009947602,0.0004725422,0.00083845516,0.00011638364,0.00046329448],"domain_scores_gemma":[0.99877584,0.00003333967,0.00010284214,0.0007727813,0.00016061259,0.00015455563],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010989802,0.00028616044,0.0004962142,0.00011527133,0.000046213197,0.000012866465,0.00029704394,0.00031315562,0.00003228917],"category_scores_gemma":[0.000023946002,0.00028207662,0.00013777202,0.0002683814,0.00008649129,0.0000019574143,0.0003333627,0.00019042386,0.0000016950701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039645478,0.00010076908,0.0004651614,0.000052136886,0.000107859,0.000028044828,0.00008855235,0.0019452883,0.9944518,0.000054968412,0.00007132843,0.0025944277],"study_design_scores_gemma":[0.00052512536,0.0004133674,0.00023952333,0.000014266768,0.00004614506,0.000035177305,0.00013274298,0.000046779296,0.98653823,0.00009986071,0.011584156,0.00032462427],"about_ca_topic_score_codex":0.00015087318,"about_ca_topic_score_gemma":0.00010667903,"teacher_disagreement_score":0.13888668,"about_ca_system_score_codex":0.000026976546,"about_ca_system_score_gemma":0.000082694336,"threshold_uncertainty_score":0.99996316},"labels":[],"label_agreement":null},{"id":"W3210443040","doi":"10.1016/j.stemcr.2021.10.004","title":"PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs","year":2021,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"Université Libanaise; Fondation Leducq; Agence Nationale de la Recherche; Institut Français de Bioinformatique","keywords":"PCSK9; Proprotein convertase; Biology; Proprotein Convertases; Cell biology; Degron; Kexin; Regulator; Small hairpin RNA; LDL receptor; Cell growth; RNA interference; Signal transduction; Lipoprotein; Cholesterol; Cell culture; Genetics; Biochemistry; Gene knockdown; Ubiquitin ligase; RNA; Gene; Ubiquitin","score_opus":0.005942363315127334,"score_gpt":0.22236102121902385,"score_spread":0.2164186579038965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210443040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931776,0.004424033,0.0014251781,0.00005976345,0.00013482918,0.000111272304,8.453546e-7,0.0000067116734,0.0006597888],"genre_scores_gemma":[0.9985019,0.00003847261,0.00018293558,0.00003644177,0.00010725935,0.000011312916,0.000033524968,0.0000126521145,0.0010755152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992957,0.000031471984,0.0002066401,0.0002509112,0.00008289207,0.00013235598],"domain_scores_gemma":[0.9996214,0.000008089736,0.00005095552,0.00024747424,0.000038883027,0.00003322645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021039655,0.000088542205,0.00008147164,0.000014319118,0.000046045803,0.000030735868,0.00002954208,0.00007457133,0.0000058480664],"category_scores_gemma":[0.000010402817,0.00007291697,0.00003227456,0.000055650973,0.000016792857,0.0000019465756,0.00005342381,0.000060277474,5.4217134e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000035815858,0.000012773878,0.003223583,0.000029387062,0.0000056092995,0.00016023449,0.00010696226,0.0013579252,0.99390906,0.000007974858,0.000038143582,0.0011447563],"study_design_scores_gemma":[0.00008960911,0.000023530212,0.00055391534,0.0000131921215,0.0000058811634,0.0001385365,0.00020547959,0.00018602583,0.99300396,0.000041744017,0.005643459,0.00009468022],"about_ca_topic_score_codex":0.000004032222,"about_ca_topic_score_gemma":0.00001850556,"teacher_disagreement_score":0.0056053153,"about_ca_system_score_codex":0.000005732636,"about_ca_system_score_gemma":0.00005313768,"threshold_uncertainty_score":0.2973468},"labels":[],"label_agreement":null},{"id":"W3210452394","doi":"10.1186/s13068-021-02057-y","title":"CRISPR/Cas9-mediated genome editing directed by a 5S rRNA–tRNAGly hybrid promoter in the thermophilic filamentous fungus Humicola insolens","year":2021,"lang":"en","type":"article","venue":"Biotechnology for Biofuels","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"National Key Research and Development Program of China; Agricultural Science and Technology Innovation Program; Chinese Academy of Sciences","keywords":"Thermophile; Biology; CRISPR; Genetics; Genome editing; Genome; Ribosomal RNA; Computational biology; Gene; Bacteria","score_opus":0.007034129146453805,"score_gpt":0.26157128435317983,"score_spread":0.25453715520672604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210452394","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98609406,0.0071115866,0.003088304,0.0020758926,0.00029048062,0.00068706775,0.0003956965,0.00013591438,0.000120999226],"genre_scores_gemma":[0.99647814,0.00063198287,0.000693567,0.00061849324,0.0002712168,0.00019165812,0.0008308467,0.00005275408,0.00023135588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822605,0.00006729874,0.00035566205,0.00062467897,0.00012771653,0.00059857656],"domain_scores_gemma":[0.9990918,0.00004211975,0.00009969327,0.000633769,0.000076576245,0.000056048128],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025714264,0.00029291314,0.00026521043,0.00011679001,0.00011775448,0.000044031272,0.0004689647,0.00057345815,0.000020527068],"category_scores_gemma":[0.00031792116,0.00025278216,0.00014036169,0.00031867466,0.00013693773,0.000004873787,0.0001812618,0.000329614,0.000010220176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028105089,0.0001224527,0.00015453214,0.000045668305,0.00006850689,0.000039232542,0.000091468755,0.000008340032,0.9937018,0.000022235812,0.0012980213,0.004419626],"study_design_scores_gemma":[0.0008258514,0.00028305955,0.0010475633,0.000019609699,0.000028550956,0.0001347795,0.0002365045,0.00013278412,0.8767597,0.00013264945,0.12009587,0.0003030828],"about_ca_topic_score_codex":0.000012649166,"about_ca_topic_score_gemma":0.000037262376,"teacher_disagreement_score":0.11879785,"about_ca_system_score_codex":0.000031498348,"about_ca_system_score_gemma":0.000064703425,"threshold_uncertainty_score":0.99999243},"labels":[],"label_agreement":null},{"id":"W3210617552","doi":"10.5281/zenodo.3738372","title":"CRISPR-mediated introduction of single nucleotide changes in iPSCs","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Biology; Computational biology; Genetics; Gene","score_opus":0.021280979939992613,"score_gpt":0.25251503184328883,"score_spread":0.2312340519032962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210617552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95915383,0.0005508994,0.018041931,0.007863096,0.00022637357,0.00058894686,0.00018477578,0.00030404478,0.01308613],"genre_scores_gemma":[0.9978731,0.00012736917,0.00017999204,0.00012343274,0.0003851063,2.3249553e-8,0.00093684654,0.00031754503,0.000056550158],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992935,0.00006690151,0.00013600587,0.00023817105,0.00010765354,0.00015778473],"domain_scores_gemma":[0.9995717,0.0000032157154,0.00004154524,0.00017206847,0.00013453104,0.00007694498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014948295,0.00007496394,0.00008619477,0.00006723755,0.00011774611,0.000045099438,0.00025113998,0.0000474396,0.00077657157],"category_scores_gemma":[0.00041995486,0.00008577462,0.000022489858,0.00025077796,0.000048689875,0.0000053665744,0.0002989616,0.00008180416,0.0001842527],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052066116,0.000047584082,0.000012962483,0.000043535685,0.000012303697,0.0000016572419,0.00033550235,0.00031289455,0.95405173,0.000038778533,0.03458036,0.010510628],"study_design_scores_gemma":[0.00028220785,0.00035652492,0.00044370728,0.000005548369,0.000004018037,0.000008479775,0.00019092773,0.00023446842,0.23090062,0.000004354814,0.7674828,0.00008631361],"about_ca_topic_score_codex":0.0000040395503,"about_ca_topic_score_gemma":0.0000013160353,"teacher_disagreement_score":0.73290247,"about_ca_system_score_codex":0.000015970205,"about_ca_system_score_gemma":0.0000015005137,"threshold_uncertainty_score":0.85029143},"labels":[],"label_agreement":null},{"id":"W3211876746","doi":"10.1016/bs.mie.2021.08.012","title":"A detection method for the capture of genomic signatures: From disease diagnosis to genome editing","year":2021,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Amplicon; Computational biology; Genome; genomic DNA; Biology; Genome editing; Genetics; DNA sequencing; CRISPR; Computer science; DNA; Polymerase chain reaction; Gene","score_opus":0.020474925597424126,"score_gpt":0.4035905245030221,"score_spread":0.38311559890559793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3211876746","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16330118,0.009570416,0.8237871,0.00059758197,0.0017516139,0.00075068773,0.00013191071,0.000023041657,0.00008645701],"genre_scores_gemma":[0.17850639,0.00032971488,0.81793755,0.001404347,0.00061275356,0.00093739684,0.000083652165,0.00008713383,0.000101085396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9923839,0.0043713213,0.0009558588,0.0013271074,0.0001473771,0.00081444246],"domain_scores_gemma":[0.99263555,0.0056162095,0.00025265402,0.0011248596,0.00017392825,0.00019681973],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0045723473,0.00050453,0.0009194839,0.00038316377,0.00012137872,0.000019207188,0.0006741998,0.0008680852,0.00009494934],"category_scores_gemma":[0.007159058,0.000470749,0.00034488356,0.000536944,0.00019101791,0.0000067006863,0.00043578562,0.00076070905,0.0000029215075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042717962,0.00017026447,0.0010451592,0.000055509947,0.00015280007,0.000047849768,0.0004828288,0.032420155,0.9031497,0.00026361455,0.00009160052,0.061693326],"study_design_scores_gemma":[0.0019736204,0.00074505864,0.14657879,0.00006559468,0.00022244063,0.00007117419,0.0007809562,0.0018670656,0.8060251,0.006787213,0.034087323,0.0007956863],"about_ca_topic_score_codex":0.00026234644,"about_ca_topic_score_gemma":0.0018205359,"teacher_disagreement_score":0.14553362,"about_ca_system_score_codex":0.00011397658,"about_ca_system_score_gemma":0.00015880878,"threshold_uncertainty_score":0.9997744},"labels":[],"label_agreement":null},{"id":"W3212233672","doi":"10.1038/s41467-021-26989-z","title":"Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Institutes of Health; Foundation for the National Institutes of Health","keywords":"Pseudoknot; CRISPR; RNA; Computational biology; Genome editing; Trans-activating crRNA; Nucleotide; Ribose; Gene; Cas9; Chemistry; CRISPR interference; Biology; Combinatorial chemistry; Biochemistry; Enzyme","score_opus":0.01653850492674452,"score_gpt":0.3439751000443849,"score_spread":0.3274365951176404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212233672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6974141,0.135014,0.10966677,0.009595383,0.0009545179,0.0005391908,0.00016016963,0.00023364594,0.04642225],"genre_scores_gemma":[0.9473548,0.0011528984,0.050113197,0.00034321586,0.000269213,0.000021865497,0.00047753053,0.000029461655,0.0002378346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916416,0.000062424566,0.00018410097,0.00026224944,0.00012021526,0.00020685243],"domain_scores_gemma":[0.99806404,0.000043063184,0.000061389685,0.0014700786,0.00029263756,0.00006877091],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121659774,0.00014929746,0.00012825034,0.000040593764,0.00029477733,0.00007401789,0.00048093335,0.00024054786,0.0000070036645],"category_scores_gemma":[0.0002104707,0.00014266197,0.00006515898,0.0001958201,0.000086537286,0.000006026932,0.00033564895,0.00039591093,0.0000028738516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001743215,0.000118431126,0.002392378,0.000025632988,0.00013616231,0.000010025158,0.00014669188,0.0011000833,0.9871992,0.0014396813,0.00380103,0.003613255],"study_design_scores_gemma":[0.00055085693,0.000055412307,0.0049596955,0.00006883338,0.000070062546,0.00017440425,0.00034664906,0.0006563815,0.9037324,0.00006553552,0.08898035,0.000339419],"about_ca_topic_score_codex":0.000012449526,"about_ca_topic_score_gemma":0.00043718697,"teacher_disagreement_score":0.24994071,"about_ca_system_score_codex":0.000014221809,"about_ca_system_score_gemma":0.00013260212,"threshold_uncertainty_score":0.5817586},"labels":[],"label_agreement":null},{"id":"W3212686797","doi":"10.21203/rs.3.rs-962421/v1","title":"Generation of Genome-Edited Dogs by Somatic Cell Nuclear Transfer","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Welichem Biotech (Canada)","funders":"","keywords":"Somatic cell nuclear transfer; Biology; Genome; CRISPR; Indel; Somatic cell; Genetics; Gene; Genome editing; Bovine genome; Cloning (programming); Molecular biology","score_opus":0.03395486649323859,"score_gpt":0.3578986755998799,"score_spread":0.32394380910664133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212686797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809652,0.0054498636,0.01208292,0.000069914466,0.00015484926,0.0004560724,0.00016697087,0.000013307294,0.0006409146],"genre_scores_gemma":[0.9943124,0.0021277103,0.000571179,0.000014503327,0.00038648568,0.00004715672,0.002026885,0.000057539593,0.0004561227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824303,0.00017438861,0.00028830406,0.0004907854,0.00045862724,0.00034484197],"domain_scores_gemma":[0.9988385,0.000016048185,0.00002729739,0.00064602785,0.00035488923,0.00011725201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040063463,0.00019002851,0.00023562658,0.000110401015,0.00006848252,0.00006783168,0.00029823935,0.00041328574,0.00021319825],"category_scores_gemma":[0.00006317746,0.0002033412,0.00016782738,0.0001334107,0.00006371701,0.0000020383181,0.00037147975,0.0004521595,0.0000088516235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001269207,0.00009949424,0.000080295096,0.0010429191,0.000051590374,0.0000032797618,0.0002797017,0.0034661558,0.991798,0.0000045153893,0.0028450903,0.00031629944],"study_design_scores_gemma":[0.00043466807,0.00027943173,0.00071578857,0.00013817045,0.000024824003,0.000003206178,0.00038917738,0.0037954994,0.97834164,0.000010695397,0.015541765,0.00032515917],"about_ca_topic_score_codex":0.000069480186,"about_ca_topic_score_gemma":0.000024943354,"teacher_disagreement_score":0.013456351,"about_ca_system_score_codex":0.000031499476,"about_ca_system_score_gemma":0.00016107924,"threshold_uncertainty_score":0.8292014},"labels":[],"label_agreement":null},{"id":"W3213499926","doi":"10.1101/2021.11.02.464583","title":"Marker-free coselection for successive rounds of prime editing in human cells","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Computational biology; Point mutation; Biology; DNA; Mutant; Tandem; Genome editing; Genetics; Cell biology; Gene; CRISPR","score_opus":0.007054057536745723,"score_gpt":0.2522669539183397,"score_spread":0.24521289638159396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213499926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94155127,0.001488083,0.055251032,0.000023180011,0.00092746835,0.0005743382,0.00013943708,0.000035903926,0.000009280235],"genre_scores_gemma":[0.9923159,0.00012612867,0.006508014,0.000023358072,0.0007324588,0.0001853882,0.000004672273,0.00009378072,0.000010283282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981053,0.00006286236,0.0005117114,0.00074826094,0.00017562219,0.0003962743],"domain_scores_gemma":[0.9982028,0.000027768614,0.00030677422,0.00094318937,0.0004232046,0.00009628654],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004168509,0.00035524392,0.00042348713,0.00015764013,0.000069063615,0.00007602519,0.0004361422,0.0005404217,0.0000089199075],"category_scores_gemma":[0.00024006283,0.00044697925,0.00018014507,0.00021611822,0.000052944604,0.00000736257,0.00046526996,0.00031187962,4.1972507e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002376867,0.00008278439,0.0021393758,0.0004649423,0.00009288382,0.0000053901927,0.0000061707124,0.0009489462,0.9960418,0.000024434104,0.00016577041,0.0000037548295],"study_design_scores_gemma":[0.0006488411,0.000097374534,0.009370446,0.00026291382,0.00005284488,1.3552758e-8,0.000009498073,0.0006596537,0.98770297,0.0000010367548,0.00078240753,0.00041198372],"about_ca_topic_score_codex":0.000061440216,"about_ca_topic_score_gemma":0.00003561135,"teacher_disagreement_score":0.05076464,"about_ca_system_score_codex":0.00008694278,"about_ca_system_score_gemma":0.00028062737,"threshold_uncertainty_score":0.9997982},"labels":[],"label_agreement":null},{"id":"W3213624809","doi":"10.1016/j.jglr.2021.10.018","title":"Genetic control of invasive sea lamprey in the Great Lakes","year":2021,"lang":"en","type":"article","venue":"Journal of Great Lakes Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Great Lakes Fishery Commission","keywords":"Lamprey; Biology; Gene drive; Fishery; Fishing; Ecology; Gene; Genetics","score_opus":0.026647266320181585,"score_gpt":0.3476416665455398,"score_spread":0.3209944002253582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213624809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895317,0.007797094,0.00095088006,0.00051681505,0.00007868855,0.00012636722,0.000015253219,0.0000010599286,0.0009821343],"genre_scores_gemma":[0.997299,0.0016571111,0.00024785745,0.00006199663,0.00029292837,0.0000062098165,0.0000051636594,0.000013390971,0.00041634997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835986,0.0003433283,0.00035702426,0.00015351363,0.0004967953,0.0002894898],"domain_scores_gemma":[0.9987377,0.00018880927,0.000077234596,0.0003148671,0.0006036284,0.000077769684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091937673,0.0001035034,0.00022343015,0.0001318642,0.000048400656,0.000035122244,0.00036619266,0.00010442931,0.000053132775],"category_scores_gemma":[0.000633364,0.00007309776,0.00014063742,0.00027188423,0.00011300457,0.0000047719586,0.000070551796,0.00032595047,0.0000025551435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003047961,0.000121827965,0.06638375,0.00011103735,0.00015851743,0.0004888382,0.00052843353,0.0023383042,0.9227858,0.000036235233,0.002775099,0.0039673243],"study_design_scores_gemma":[0.003916824,0.0020508864,0.12855323,0.00025568332,0.00007114389,0.001396375,0.0018582962,0.00032840495,0.8279285,0.0003433918,0.033005282,0.0002919703],"about_ca_topic_score_codex":0.000014796225,"about_ca_topic_score_gemma":0.00056254514,"teacher_disagreement_score":0.09485733,"about_ca_system_score_codex":0.000017441584,"about_ca_system_score_gemma":0.0002791863,"threshold_uncertainty_score":0.29808402},"labels":[],"label_agreement":null},{"id":"W3214126101","doi":"10.3389/fpubh.2021.773175","title":"Gene Therapy Knowledge and Attitude Among Healthcare Professionals: A Cross-Sectional Study","year":2021,"lang":"en","type":"article","venue":"Frontiers in Public Health","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Family medicine; Cross-sectional study; Health professionals; Health care; Pathology","score_opus":0.027824868552410228,"score_gpt":0.3869383523635285,"score_spread":0.3591134838111183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214126101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97198254,0.019355705,0.0062604095,0.0009495138,0.00096206716,0.00037728244,0.000016013224,0.000016025737,0.00008043085],"genre_scores_gemma":[0.9949258,0.0014012421,0.0023328036,0.00043914537,0.00022842058,0.00007530113,0.0001119139,0.00002173426,0.00046362032],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99848855,0.00021679336,0.00031810525,0.00045496758,0.0001395815,0.0003819924],"domain_scores_gemma":[0.9993292,0.000008652762,0.000053063115,0.00026078377,0.00012159928,0.0002266871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076383783,0.00013799247,0.0001954538,0.000089217116,0.00014409743,0.000053931348,0.000112291236,0.00012622833,0.00000976325],"category_scores_gemma":[0.000066058165,0.00013807048,0.00003966687,0.00019884488,0.00005086651,0.0000073960405,0.00010910913,0.00017772932,7.7453853e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014244752,0.0003552531,0.98750263,0.00004316556,0.000043293927,0.0000042493634,0.00054979324,0.000016082202,0.00037449508,0.000012428744,0.0023617533,0.008722591],"study_design_scores_gemma":[0.00093411026,0.00020519306,0.9808822,0.000009793026,6.839486e-7,0.000011617465,0.00061921356,0.0000992004,0.00078432634,0.000023859602,0.016295535,0.00013421864],"about_ca_topic_score_codex":0.000063475236,"about_ca_topic_score_gemma":0.0002888532,"teacher_disagreement_score":0.022943266,"about_ca_system_score_codex":0.00006637134,"about_ca_system_score_gemma":0.00073983625,"threshold_uncertainty_score":0.5630351},"labels":[],"label_agreement":null},{"id":"W3214390946","doi":"10.1093/plphys/kiab526","title":"Suicide prevention for enzymes using continuous directed evolution","year":2021,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Enzyme; Computational biology; Biology; Chemistry; Biochemistry","score_opus":0.01373635182918985,"score_gpt":0.29761681468636914,"score_spread":0.28388046285717927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214390946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9417032,0.002413271,0.05533657,0.000019611927,0.00026187047,0.00012288694,0.000066476954,0.000023512295,0.000052598134],"genre_scores_gemma":[0.9952581,0.00006937343,0.0031272233,0.00004194423,0.00026996995,0.000018948043,0.00091210037,0.000012361132,0.0002899938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999423,0.00003204896,0.00011326555,0.00022635206,0.000029469418,0.00017583763],"domain_scores_gemma":[0.9997212,0.00001728533,0.000034777993,0.00013689062,0.00006288439,0.000026959477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043490454,0.0000851798,0.00012214239,0.000017657248,0.00004360479,0.0000053145623,0.00004688185,0.00009341839,0.000010250297],"category_scores_gemma":[0.00005693076,0.000089052504,0.00006979908,0.000037631515,0.000016366032,0.0000014776163,0.00003618712,0.000031822707,0.0000014955676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055135184,0.00002838818,0.0002011494,0.00002058978,0.000038797712,0.0000010831401,0.0000073247816,0.0009638506,0.99757653,0.00017850593,0.00056393235,0.00036473732],"study_design_scores_gemma":[0.00045640097,0.00012447771,0.0060218526,0.00002008625,0.000030612126,0.00003269228,0.000038350732,0.0038808016,0.984859,0.0007080029,0.0036804867,0.00014725074],"about_ca_topic_score_codex":0.00001061631,"about_ca_topic_score_gemma":0.000033397813,"teacher_disagreement_score":0.05355488,"about_ca_system_score_codex":0.00000976593,"about_ca_system_score_gemma":0.00004803325,"threshold_uncertainty_score":0.36314556},"labels":[],"label_agreement":null},{"id":"W3214686216","doi":"10.1016/j.aquatox.2021.106021","title":"The freshwater water flea Daphnia magna NIES strain genome as a resource for CRISPR/Cas9 gene targeting: The glutathione S-transferase omega 2 gene","year":2021,"lang":"en","type":"article","venue":"Aquatic Toxicology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Sainte-Anne","funders":"Ministry of Oceans and Fisheries","keywords":"Daphnia magna; Genome; Biology; Genetics; CRISPR; Gene; Strain (injury); Chemistry","score_opus":0.008515166607772672,"score_gpt":0.2705389627442446,"score_spread":0.2620237961364719,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214686216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94707894,0.005676598,0.038873777,0.0069384193,0.00038962343,0.0006474265,0.00017442754,0.00003209764,0.00018867434],"genre_scores_gemma":[0.9907512,0.00036678487,0.0030263443,0.0018677205,0.0006257194,0.00026207403,0.0006555631,0.00007026549,0.0023743277],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794483,0.00020356347,0.00042800457,0.0005299239,0.00016536882,0.00072833104],"domain_scores_gemma":[0.99893475,0.0001639448,0.000047073245,0.0006505543,0.00008765383,0.00011604835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006059837,0.00028901576,0.0002528545,0.000034516543,0.00044683163,0.000084914536,0.00041355967,0.00024400554,0.0000910288],"category_scores_gemma":[0.00024510792,0.00017529039,0.00019729589,0.0000847411,0.00020278836,0.0000041589446,0.00017881244,0.00019403486,0.000036503294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012403283,0.0000539564,0.00002029834,0.000023912598,0.00017710037,0.00001910017,0.00063122046,0.0009865313,0.9951145,0.00015066208,0.0017146834,0.000984013],"study_design_scores_gemma":[0.0006405751,0.0005867276,0.000085695305,0.000002993113,0.00006441008,0.00009452697,0.0004750737,0.00034555097,0.72035766,0.0005825264,0.2765397,0.00022455551],"about_ca_topic_score_codex":0.0000104663395,"about_ca_topic_score_gemma":0.00047269554,"teacher_disagreement_score":0.27482504,"about_ca_system_score_codex":0.000021762748,"about_ca_system_score_gemma":0.00010012401,"threshold_uncertainty_score":0.7148135},"labels":[],"label_agreement":null},{"id":"W3216011146","doi":"10.1101/2021.11.21.469464","title":"Theoretical Guarantees for Phylogeny Inference from Single-Cell Lineage Tracing","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Indel; CRISPR; Inference; Lineage (genetic); Phylogenetic tree; Tracing; Phylogenetics; Computer science; Theoretical computer science; Tree (set theory); R package; Algorithm; Biology; Evolutionary biology; Computational biology; Artificial intelligence; Mathematics; Combinatorics; Genetics; Computational science","score_opus":0.010466008694813754,"score_gpt":0.24842536401604332,"score_spread":0.23795935532122955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216011146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8134716,0.0045360955,0.1801764,0.000035974917,0.0008210752,0.00045025646,0.00041185715,0.00008272185,0.000013969901],"genre_scores_gemma":[0.97334003,0.00035639905,0.024660602,0.00014520605,0.001165083,0.00016806596,0.0000122194815,0.00014774797,0.000004642007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974861,0.000074781456,0.0004914981,0.001185786,0.00021149754,0.0005502949],"domain_scores_gemma":[0.9979382,0.000090827634,0.0001827836,0.0012148586,0.0003721704,0.00020113667],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027160117,0.00057187624,0.0005128504,0.00008145315,0.00010132399,0.00022100126,0.00052180287,0.0007832964,0.000058835518],"category_scores_gemma":[0.00040118577,0.0006410637,0.00031427763,0.00012638615,0.0001435956,0.0000059606928,0.0005040851,0.00043632643,0.000006030231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039779075,0.00015412246,0.00051152956,0.00025974767,0.00012898727,0.000014897073,0.00001276416,0.0010225867,0.99763876,0.0001490734,0.000062101244,0.0000056790673],"study_design_scores_gemma":[0.000563653,0.00011789218,0.0024590036,0.00022516803,0.00013447744,1.698599e-8,0.000009850242,0.0022137084,0.9922712,0.0000041607905,0.001241496,0.0007593818],"about_ca_topic_score_codex":0.000015616757,"about_ca_topic_score_gemma":0.000004633265,"teacher_disagreement_score":0.15986839,"about_ca_system_score_codex":0.00004625134,"about_ca_system_score_gemma":0.00030776966,"threshold_uncertainty_score":0.99960405},"labels":[],"label_agreement":null},{"id":"W3216123921","doi":"10.1038/s43705-021-00037-9","title":"RNA-editing in Basidiomycota, revisited","year":2021,"lang":"en","type":"article","venue":"ISME Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Joint Genome Institute; U.S. Department of Energy; Office of Science; National Science Foundation","keywords":"Basidiomycota; RNA; Computational biology; Biology; Genetics; Gene; Botany","score_opus":0.018497239273016143,"score_gpt":0.33435678781554967,"score_spread":0.3158595485425335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216123921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8182687,0.054948315,0.037270408,0.009985619,0.0003265069,0.00038355932,0.0000692054,0.00009009202,0.07865758],"genre_scores_gemma":[0.9893667,0.001324142,0.008405567,0.00018845746,0.000070888265,0.000017323251,0.0002269241,0.000010924536,0.00038906367],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995242,0.00005360717,0.00014147429,0.00012692895,0.000042255437,0.00011153265],"domain_scores_gemma":[0.9988483,0.000019526651,0.000021675856,0.0010196415,0.000059245518,0.000031612784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100758705,0.000059491744,0.0000682326,0.0000281004,0.00005589557,0.000015164663,0.00027045983,0.000053023323,0.000028916602],"category_scores_gemma":[0.00013648327,0.00007138041,0.000038221362,0.00015133324,0.000025505951,0.0000017255966,0.00026962612,0.00009752145,0.000010963458],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000024555757,0.00007585727,0.0057796123,0.00001747632,0.00002329466,0.0000051021866,0.00014141329,0.0003463839,0.9810602,0.0011762936,0.0024283237,0.008943604],"study_design_scores_gemma":[0.0007009325,0.000037000485,0.03299298,0.00011525016,0.000021542983,0.000055205244,0.0005198357,0.0022820595,0.45324668,0.00029611355,0.50937426,0.00035814202],"about_ca_topic_score_codex":0.000010850419,"about_ca_topic_score_gemma":0.00014932184,"teacher_disagreement_score":0.5278135,"about_ca_system_score_codex":0.000008873645,"about_ca_system_score_gemma":0.000035700577,"threshold_uncertainty_score":0.29108086},"labels":[],"label_agreement":null},{"id":"W3217257831","doi":"10.1093/plphys/kiab535","title":"CRISPR–Cas9-mediated editing of starch branching enzymes results in altered starch structure in <i>Brassica napus</i>","year":2021,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Mutant; Gene; Starch; Genetics; CRISPR; Biochemistry; Molecular biology","score_opus":0.007746156015224887,"score_gpt":0.27039344051149095,"score_spread":0.26264728449626606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217257831","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99739796,0.0012074438,0.000114423165,0.00012588168,0.00030581254,0.00010428191,0.0006424045,0.0000082272445,0.000093593706],"genre_scores_gemma":[0.99684995,0.00025574735,0.00052407326,0.00009975922,0.0003286055,0.000007450149,0.0019018626,0.000018471494,0.000014062019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847925,0.00013537021,0.00043172823,0.00045392406,0.00010638298,0.0003933376],"domain_scores_gemma":[0.99939114,0.000118193006,0.00008741291,0.0002992934,0.000051441606,0.00005253709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014981319,0.00017604812,0.00032291125,0.00010001396,0.000024208503,0.0000070994115,0.00017066013,0.00018794056,0.00001652774],"category_scores_gemma":[0.00028777946,0.00017837221,0.000053152933,0.00018965077,0.000050385606,0.000004456267,0.00015659843,0.00027420337,0.0000010626853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040783206,0.00005242306,0.0016392733,0.00008537168,0.00002555196,0.000023628929,0.0003429162,0.0031522594,0.993503,0.000022812583,0.00033953838,0.00040540277],"study_design_scores_gemma":[0.0014813319,0.00022110726,0.031295143,0.00007509618,0.0000054158213,0.000023986979,0.00026252223,0.00072754547,0.9627706,0.000114603106,0.002814826,0.00020782078],"about_ca_topic_score_codex":0.00011096676,"about_ca_topic_score_gemma":0.0012047564,"teacher_disagreement_score":0.030732388,"about_ca_system_score_codex":0.000014548873,"about_ca_system_score_gemma":0.00009805654,"threshold_uncertainty_score":0.72738075},"labels":[],"label_agreement":null},{"id":"W33020655","doi":"10.1038/s41592-020-0966-x","title":"O-1-206 CD155/PVRを標的とした大腸癌に対する分子標的治療の基礎的検討(大腸 研究1,一般演題(口演),第63回日本消化器外科学会総会)","year":2008,"lang":"en","type":"article","venue":"日本消化器外科学会雑誌","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; University of Toronto; Government of Canada; Canadian Institute for Advanced Research","keywords":"Computer science","score_opus":0.007805140151099455,"score_gpt":0.2749046102936407,"score_spread":0.26709947014254126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W33020655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.967369,0.0038209537,0.0150253745,0.00027454062,0.00087034225,0.00033823831,0.000044310582,0.00015160292,0.012105607],"genre_scores_gemma":[0.9883462,0.00073206425,0.0021042295,0.0005146732,0.0009132862,0.000050519197,0.00016574198,0.00008642178,0.0070868246],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978693,0.000047632268,0.00040440288,0.0006945492,0.0003166599,0.0006674574],"domain_scores_gemma":[0.99863976,0.000021962453,0.000084054795,0.00087144575,0.000116449206,0.00026635232],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018062476,0.0003992743,0.00031711572,0.00010146878,0.00023963333,0.00003173885,0.00043586522,0.000301652,0.00013923922],"category_scores_gemma":[0.00011540434,0.00040234544,0.00025048578,0.00022200718,0.00016582222,0.000008733321,0.00020650188,0.00023078303,0.00027918327],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015449684,0.00030722542,0.011070633,0.00008804913,0.00023901864,0.00014735795,0.00042373562,0.0019030734,0.91472715,0.0007620739,0.062760726,0.007416474],"study_design_scores_gemma":[0.0016739313,0.000526588,0.020660823,0.000035526737,0.000057901994,0.0005520767,0.00013546438,0.00060647924,0.47251424,0.00012695506,0.50198907,0.0011209548],"about_ca_topic_score_codex":0.000045915338,"about_ca_topic_score_gemma":0.00004118765,"teacher_disagreement_score":0.4422129,"about_ca_system_score_codex":0.000029162191,"about_ca_system_score_gemma":0.00011253393,"threshold_uncertainty_score":0.9998428},"labels":[],"label_agreement":null},{"id":"W394507619","doi":"10.1371/journal.pbio.1002155","title":"The Fitness Consequences of Aneuploidy Are Driven by Condition-Dependent Gene Effects","year":2015,"lang":"en","type":"article","venue":"PLoS Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Canadian Institute for Advanced Research; National Cancer Institute; National Science Foundation; National Institutes of Health; March of Dimes Foundation; National Institute on Aging","keywords":"Biology; Aneuploidy; Genetics; Ploidy; Genetic Fitness; Genome; Amplicon; Gene; Saccharomyces cerevisiae; Experimental evolution; Population; Evolutionary biology; Chromosome; Polymerase chain reaction","score_opus":0.011111252153373346,"score_gpt":0.29701795170836526,"score_spread":0.2859066995549919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W394507619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936883,0.004081388,0.0013972168,0.00021175575,0.00023131,0.00015330502,0.00007185905,0.00001096408,0.00015389868],"genre_scores_gemma":[0.9991181,0.00026864672,0.000118055206,0.00008646465,0.000091833055,0.000035170095,0.00014089428,0.000009810033,0.00013103757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993457,0.000070682014,0.0001510256,0.0001934279,0.00006252124,0.0001766126],"domain_scores_gemma":[0.99949735,0.00005210171,0.00007646094,0.00022094221,0.00008624366,0.00006691948],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010042354,0.00010304839,0.00013742689,0.000015046711,0.000045975306,0.0000063363605,0.00018969664,0.00011976896,0.0000039329634],"category_scores_gemma":[0.00015928262,0.00007424805,0.00003751088,0.000034269164,0.0002242634,0.0000011556855,0.00006803175,0.000054387252,0.0000062216395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021062522,0.000028334895,0.008332643,0.000015918977,0.00006186498,0.0000018902468,0.000021641734,0.00008314282,0.98967993,0.00006211784,0.0015244333,0.00016699362],"study_design_scores_gemma":[0.00036216402,0.0002964282,0.0010879926,0.0000073507117,0.00001746775,0.000014335154,0.000072582465,0.000037079295,0.99462163,0.000207318,0.0031737792,0.00010185078],"about_ca_topic_score_codex":0.000015022167,"about_ca_topic_score_gemma":0.000016124737,"teacher_disagreement_score":0.0072446503,"about_ca_system_score_codex":0.000007046118,"about_ca_system_score_gemma":0.0000408763,"threshold_uncertainty_score":0.30277476},"labels":[],"label_agreement":null},{"id":"W4200008328","doi":"10.1158/1535-7163.targ-21-p096","title":"Abstract P096: Using CRISPR-Cas9 screens to identify microRNA involved in aggressive prostate cancer phenotypes","year":2021,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; microRNA; DU145; Prostate cancer; Cas9; Biology; Cancer research; In silico; Computational biology; Cancer; Gene knockout; Metastasis; Guide RNA; Phenotype; Gene; Bioinformatics; Genetics; LNCaP","score_opus":0.025782153819473522,"score_gpt":0.36377515183888737,"score_spread":0.33799299801941385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200008328","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500488,0.04013015,0.008458604,0.0005316476,0.00035928073,0.00028626446,0.00008058347,0.000016444086,0.000088239605],"genre_scores_gemma":[0.9926682,0.0027648916,0.0018903216,0.0021879503,0.00017529512,0.000069933696,0.000049871007,0.00007927411,0.000114226736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844193,0.000046554702,0.00029889814,0.0005393815,0.00020038178,0.00047285415],"domain_scores_gemma":[0.9991308,0.000007071106,0.00010769224,0.00043073928,0.0002020122,0.000121697165],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009631641,0.0002797024,0.00023818282,0.000078721285,0.00006263183,0.000065619126,0.00020981887,0.00016715682,0.000052415384],"category_scores_gemma":[0.000021331616,0.0003096043,0.000117239106,0.00029358495,0.000042253112,0.0000057935745,0.0001449223,0.00018394474,0.000005172762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068710484,0.00004693622,0.0037484113,0.00005372705,0.000175342,0.00012334784,0.00028433444,0.022003047,0.9658729,0.0000073768515,0.00008103465,0.007534845],"study_design_scores_gemma":[0.0006376038,0.00003708002,0.010216455,0.00017163929,0.000071477785,0.000008675947,0.00019846017,0.00035966063,0.9756383,0.000044453787,0.0122001,0.00041611757],"about_ca_topic_score_codex":0.00039683864,"about_ca_topic_score_gemma":0.0013751695,"teacher_disagreement_score":0.04261945,"about_ca_system_score_codex":0.000088897956,"about_ca_system_score_gemma":0.00028033074,"threshold_uncertainty_score":0.9999356},"labels":[],"label_agreement":null},{"id":"W4200090581","doi":"10.1089/crispr.2021.0091","title":"Using the CRISPR-Cas System to Solve Porcine Viral Infection–related Issues","year":2021,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Xenotransplantation; Biology; Viral infection; Virology; Endogenous retrovirus; Computational biology; Virus; Gene; Medicine; Genetics; Genome; Transplantation","score_opus":0.039585850046360886,"score_gpt":0.41413505083062757,"score_spread":0.3745492007842667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200090581","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003274676,0.96277004,0.034174275,0.0002197772,0.0017724439,0.00045016638,0.000016143986,0.000023905406,0.00024575592],"genre_scores_gemma":[0.0015023877,0.99423707,0.0005506781,0.00010380985,0.0027421247,0.000024830963,0.00004212656,0.00010918098,0.00068782485],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977164,0.00030602005,0.0008073511,0.00038786535,0.00029540694,0.00048695554],"domain_scores_gemma":[0.9984733,0.000040320283,0.00033846262,0.0007660039,0.00020288036,0.00017902166],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009437334,0.00050887914,0.0008990241,0.00011550874,0.0005548295,0.0002472208,0.00057658367,0.0003689641,0.000061369734],"category_scores_gemma":[0.00012166822,0.00028990651,0.00077332463,0.00029293093,0.000062179846,0.000005446821,0.00033108977,0.0009338246,0.000033866116],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010864843,0.00032206374,0.00008260013,0.015443206,0.009819939,0.0008302759,0.0024715532,0.024849378,0.015343995,0.0015255762,0.14215122,0.78705156],"study_design_scores_gemma":[0.00016391528,0.000103836755,0.0000069231596,0.0032509647,0.0011021884,0.0062501677,0.00024132701,0.000108961474,0.0014987245,0.000008873702,0.98686767,0.00039642854],"about_ca_topic_score_codex":0.00006288803,"about_ca_topic_score_gemma":0.0000139442955,"teacher_disagreement_score":0.8447165,"about_ca_system_score_codex":0.00012021018,"about_ca_system_score_gemma":0.00026392168,"threshold_uncertainty_score":0.9999553},"labels":[],"label_agreement":null},{"id":"W4200122398","doi":"10.1101/2021.12.19.473358","title":"Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in <i>Drosophila melanogaster</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Instituto Nacional de Cancerología","keywords":"EIF4E; Biology; Spermatid; Eukaryotic initiation factor; Initiation factor; Drosophila melanogaster; Cell biology; Eukaryotic translation; Genetics; Eukaryotic translation initiation factor 4 gamma; Translation (biology); Sperm; Gene; Messenger RNA","score_opus":0.020942531552675243,"score_gpt":0.2636913476830074,"score_spread":0.24274881613033214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200122398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97248614,0.0039450466,0.021236952,0.00018949142,0.00079286343,0.0008394233,0.00044571594,0.000058296133,0.00000605928],"genre_scores_gemma":[0.9916029,0.00079756626,0.006406428,0.00022941588,0.0005726667,0.00023880761,0.000016287908,0.00013102056,0.0000049023806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977371,0.00007305551,0.00054946926,0.0009788846,0.00021359393,0.0004478669],"domain_scores_gemma":[0.9985654,0.000028001541,0.00018685985,0.00082376663,0.0002555631,0.00014040564],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023849831,0.0004692702,0.00043835602,0.00017897916,0.000065786575,0.00011977145,0.0002912081,0.0006717957,0.000020861535],"category_scores_gemma":[0.00010491781,0.0005810458,0.00024293111,0.00023241379,0.00003610775,0.000014586096,0.00015828517,0.00022545227,0.0000046095643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045818044,0.00006856004,0.005409693,0.00040452636,0.00009051223,0.000009522524,0.00003163065,0.0006467155,0.9932152,0.0000071575164,0.00005688793,0.000013756096],"study_design_scores_gemma":[0.00085512287,0.0000794245,0.06302287,0.00020042114,0.00007940705,4.126099e-8,0.0000059098293,0.0009915764,0.93274623,0.0000012446005,0.0013727078,0.0006450347],"about_ca_topic_score_codex":0.000015435195,"about_ca_topic_score_gemma":0.000014922749,"teacher_disagreement_score":0.06046898,"about_ca_system_score_codex":0.000082798964,"about_ca_system_score_gemma":0.00032413163,"threshold_uncertainty_score":0.99966407},"labels":[],"label_agreement":null},{"id":"W4200161123","doi":"10.21203/rs.3.rs-1105540/v1","title":"Prime Editor-mediated Correction of a Pathogenic Mutation in Purebred Dogs","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Welichem Biotech (Canada)","funders":"Rural Development Administration","keywords":"Purebred; Mutation; Disease; Somatic cell; Labrador Retriever; Medicine; Biology; Genetics; Internal medicine; Pathology; Breed; Gene","score_opus":0.015436581862337153,"score_gpt":0.36966516415796147,"score_spread":0.3542285822956243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200161123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905685,0.0035827432,0.0027276846,0.000042462154,0.0022347907,0.0005613055,0.00005307258,0.000013514394,0.00021592397],"genre_scores_gemma":[0.99574304,0.0007448393,0.00023172137,0.000003891629,0.0012220473,0.000121036916,0.0017394118,0.000030543393,0.00016345539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998229,0.00024560292,0.00029506118,0.00047086572,0.000446104,0.00031332765],"domain_scores_gemma":[0.9988514,0.000053328986,0.00006659461,0.00047470196,0.0004765227,0.000077436416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007071197,0.00015298849,0.00021475698,0.000238845,0.000029487477,0.000033904573,0.00019234687,0.0004741478,0.00002853289],"category_scores_gemma":[0.0007936261,0.00017108957,0.00011944642,0.00029321187,0.000052435375,0.000002175946,0.00045302685,0.00059637806,0.000004098957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086367574,0.00014407527,0.003212648,0.00056094443,0.000056200603,0.00002873734,0.000377247,0.009069107,0.9793269,0.0000010534986,0.0021020095,0.0050347196],"study_design_scores_gemma":[0.0012156732,0.0006404584,0.07463504,0.001044501,0.000022145883,0.000018922305,0.0013706574,0.011233661,0.9044503,0.00004528038,0.0047695944,0.00055378006],"about_ca_topic_score_codex":0.0002817922,"about_ca_topic_score_gemma":0.00038170716,"teacher_disagreement_score":0.07487661,"about_ca_system_score_codex":0.000067430534,"about_ca_system_score_gemma":0.0004330781,"threshold_uncertainty_score":0.69768304},"labels":[],"label_agreement":null},{"id":"W4200201724","doi":"10.22541/au.163717150.01158451/v1","title":"High-efficiency retron-mediated single-stranded DNA production in plants","year":2021,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kootenay Association for Science & Technology","funders":"King Abdullah University of Science and Technology","keywords":"Nicotiana benthamiana; DNA; Gene; Biology; Yeast; Cell biology; Computational biology; Genetics","score_opus":0.01057791426288524,"score_gpt":0.25975449162573333,"score_spread":0.2491765773628481,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200201724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909672,0.00093241024,0.0058058216,0.00013093415,0.0013178465,0.0002748556,0.000020787555,0.00003432745,0.0005157785],"genre_scores_gemma":[0.99609697,0.0004105418,0.0011676438,0.00003117338,0.00035897552,0.000028276285,0.0013563533,0.000029336148,0.00052074564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852896,0.00003753928,0.00030564517,0.0006952231,0.00015230934,0.00028031957],"domain_scores_gemma":[0.99931604,0.0000062813724,0.00006202788,0.00049821753,0.00005594342,0.000061520186],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015394815,0.0002466494,0.0002447072,0.0000877546,0.000021978454,0.000037801005,0.00017743894,0.00041978553,0.000042667994],"category_scores_gemma":[0.00013874433,0.00025527072,0.00008413108,0.00008901612,0.000029293069,0.0000014674081,0.00025199584,0.00028380463,0.0000041012822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003490607,0.00016191603,0.0004517919,0.00009651379,0.000036186055,0.000013349256,0.0000861127,0.0166248,0.98081076,0.0000015460763,0.0004656553,0.0012164697],"study_design_scores_gemma":[0.00040566924,0.000094352676,0.003915321,0.000102446276,0.000012835484,0.000014998694,0.00014993912,0.00033998018,0.99397,0.000015272,0.0005981255,0.00038106993],"about_ca_topic_score_codex":0.000069776805,"about_ca_topic_score_gemma":0.00036454215,"teacher_disagreement_score":0.016284822,"about_ca_system_score_codex":0.000033698692,"about_ca_system_score_gemma":0.000105730694,"threshold_uncertainty_score":0.9999899},"labels":[],"label_agreement":null},{"id":"W4200234008","doi":"10.1101/2021.12.14.471503","title":"Introduction of <i>loxP</i> sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"University of California, Irvine; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada; European Genomic Institute for Diabetes","keywords":"CRISPR; Electroporation; Allele; Computational biology; Cas9; Biology; Genetics; Genome editing; Genome; Gene; Computer science","score_opus":0.011657786258246313,"score_gpt":0.24095895877601736,"score_spread":0.22930117251777105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200234008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8484425,0.0015638556,0.14897813,0.00010830467,0.000006062986,0.0006381076,0.00024898845,0.000013005278,0.0000010372322],"genre_scores_gemma":[0.97522765,0.0002099649,0.008899674,0.00009180465,0.0007876219,0.00027648313,0.014460697,0.000044401593,0.0000016911346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839866,0.0001181681,0.0004486484,0.0005965404,0.00016943295,0.0002685292],"domain_scores_gemma":[0.9991096,0.000004988735,0.00019451402,0.00040983965,0.00024468487,0.00003634065],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005737449,0.00024840998,0.00026718585,0.00008801329,0.00006042184,0.00006927659,0.0002110117,0.00027430718,0.000021846661],"category_scores_gemma":[0.00012499702,0.00026206297,0.00008765391,0.00020737157,0.000041962867,0.000010114283,0.000089445886,0.00022954048,3.4150452e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020008143,0.00013172909,0.0005635931,0.00014650903,0.000035052337,5.9410917e-7,0.00001641776,0.02813136,0.91795087,0.000040712603,0.052962717,4.1982685e-7],"study_design_scores_gemma":[0.0004270064,0.000073997784,0.0033798076,5.251741e-7,0.000022984232,2.39332e-8,0.000036054553,0.013537907,0.95149124,9.823019e-7,0.030720472,0.00030902986],"about_ca_topic_score_codex":0.000025422023,"about_ca_topic_score_gemma":0.000022019954,"teacher_disagreement_score":0.14007846,"about_ca_system_score_codex":0.00006943446,"about_ca_system_score_gemma":0.000096964606,"threshold_uncertainty_score":0.99998313},"labels":[],"label_agreement":null},{"id":"W4200239593","doi":"10.1101/2021.12.15.472800","title":"The MyLo CRISPR-Cas9 Toolkit: A Markerless Yeast Localization and Overexpression CRISPR-Cas9 Toolkit","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"CRISPR; Cas9; Genome editing; Computational biology; Selectable marker; Biology; Trans-activating crRNA; Guide RNA; Saccharomyces cerevisiae; CRISPR interference; Yeast; Gene; Genetics; Computer science; Plasmid","score_opus":0.007027796380733904,"score_gpt":0.24197013804910658,"score_spread":0.2349423416683727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200239593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.914556,0.017741127,0.064841986,0.00022462413,0.0014483619,0.0008018802,0.00020498184,0.00013572752,0.000045265],"genre_scores_gemma":[0.99241114,0.004660596,0.0015217452,0.00021490513,0.0008062645,0.00016640988,0.0000075650414,0.00016181791,0.000049545895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99694824,0.00018145851,0.000576841,0.001249811,0.0003944685,0.0006491694],"domain_scores_gemma":[0.99735063,0.000042683077,0.00026729424,0.0015932749,0.00045536048,0.00029073254],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005240008,0.00066326954,0.000455271,0.000096521966,0.00039110746,0.00058772316,0.0005595964,0.0007808898,0.000032175012],"category_scores_gemma":[0.00035022607,0.00061854656,0.00019632999,0.00026327852,0.00016097828,0.000018594004,0.0012039985,0.00056571,0.000008524955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008863242,0.000081738166,0.0032487258,0.00046313685,0.00020085441,0.000033179684,0.00002501948,0.00081088673,0.99238664,0.00009582464,0.0025136159,0.000051729523],"study_design_scores_gemma":[0.0008686448,0.000088252076,0.044965908,0.00073678215,0.00018998743,5.370454e-7,0.00007332569,0.0034189648,0.8786689,0.000002061993,0.06958117,0.0014054411],"about_ca_topic_score_codex":0.000042094114,"about_ca_topic_score_gemma":0.000012993431,"teacher_disagreement_score":0.113717735,"about_ca_system_score_codex":0.00008101359,"about_ca_system_score_gemma":0.00035548638,"threshold_uncertainty_score":0.9996266},"labels":[],"label_agreement":null},{"id":"W4200239638","doi":"10.3791/58024-v","title":"High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping","year":2018,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Zebrafish; Genotyping; Biology; Genotype; Genetics; Danio; DNA sequencing; Computational biology; genomic DNA; Gene","score_opus":0.013434686888669235,"score_gpt":0.4080271072757353,"score_spread":0.3945924203870661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200239638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96728134,0.003084384,0.029093467,0.000027336258,0.00038949464,0.000059514365,0.000004151553,0.0000035833298,0.000056742054],"genre_scores_gemma":[0.9931655,0.00039561602,0.0058610556,0.000079723664,0.0004040667,0.0000016240539,0.000007670894,0.000018756764,0.00006600503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991288,0.000037199556,0.00039170592,0.00013993404,0.00015028987,0.0001520299],"domain_scores_gemma":[0.99941975,0.000009832363,0.0002602479,0.00011401474,0.00012219699,0.000073935655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019930344,0.00011698317,0.00020482113,0.000053344895,0.000049808074,0.000018683877,0.00009513559,0.00009886039,0.0000344099],"category_scores_gemma":[0.00005047571,0.00011273099,0.000069023146,0.00005075446,0.000056615616,0.000011988372,0.00005379899,0.000069311835,0.000001250757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013690605,0.000066390625,0.00017063819,0.00001470626,0.00009015922,0.0000015363534,0.00024747592,0.000013436648,0.9965225,0.000009730657,0.0016862181,0.0010403007],"study_design_scores_gemma":[0.0011680148,0.00051534036,0.00058747863,0.000052167914,0.000022146816,0.000039451665,0.00017985902,0.00005950567,0.98655283,0.000017329197,0.01069433,0.00011152298],"about_ca_topic_score_codex":0.000014029437,"about_ca_topic_score_gemma":0.0000014091734,"teacher_disagreement_score":0.025884153,"about_ca_system_score_codex":0.000014579054,"about_ca_system_score_gemma":0.000026593072,"threshold_uncertainty_score":0.45970362},"labels":[],"label_agreement":null},{"id":"W4200252343","doi":"10.3390/cells11010076","title":"Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic Cancer Research Institute; Dr. Georges-L.-Dumont University Hospital Centre; Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Leukemia and Lymphoma Society of Canada; Fondation de la recherche en santé du Nouveau-Brunswick; Beatrice Hunter Cancer Research Institute","keywords":"Biology; Untranslated region; Three prime untranslated region; Carcinogenesis; Polyadenylation; Gene; Regulation of gene expression; Genetics; Gene expression; Messenger RNA","score_opus":0.004527779895279607,"score_gpt":0.2398679215202788,"score_spread":0.2353401416249992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200252343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97395474,0.003339701,0.020616831,0.00026832582,0.00029868857,0.00012615912,0.00005735784,0.000021517702,0.0013166858],"genre_scores_gemma":[0.98935753,0.000063742715,0.0018726873,0.00017731052,0.0003266664,0.000013877048,0.00023399154,0.000019487814,0.007934689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939513,0.00001687432,0.00011208991,0.00023361154,0.00009016042,0.00015214807],"domain_scores_gemma":[0.99970186,0.0000022043243,0.000019666797,0.00017490468,0.00004593282,0.00005540974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000044538825,0.00009033845,0.0000681023,0.000009399953,0.000042192438,0.000016324939,0.00006331849,0.00010323197,0.00020564762],"category_scores_gemma":[0.000009434999,0.00009417897,0.00005726747,0.00004338574,0.000015677184,0.0000016293262,0.000029561044,0.000058580274,0.000012198723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005422119,0.000021944501,0.00001480721,0.000019015215,0.0000089366,0.0000029167772,0.000035271278,0.00007389606,0.97235394,0.000004524366,0.026826598,0.00063275086],"study_design_scores_gemma":[0.00019703149,0.000020574376,0.00005281232,0.00002406587,0.0000040522114,0.0000041471135,0.00003580665,0.000068613284,0.8458009,0.000015237392,0.15368232,0.00009444174],"about_ca_topic_score_codex":0.0000015632113,"about_ca_topic_score_gemma":8.4962056e-7,"teacher_disagreement_score":0.12685572,"about_ca_system_score_codex":0.000004613389,"about_ca_system_score_gemma":0.000022776398,"threshold_uncertainty_score":0.3840507},"labels":[],"label_agreement":null},{"id":"W4200276894","doi":"10.3791/52807-v","title":"Transfecting RAW264.7 Cells with a Luciferase Reporter Gene","year":2015,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transfection; Luciferase; Reporter gene; Cell culture; Cell biology; Molecular biology; Plasmid; Cell; Biology; Chemistry; Gene; Gene expression; Biochemistry; Genetics","score_opus":0.022528934325352114,"score_gpt":0.4186636057374112,"score_spread":0.39613467141205905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200276894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9434541,0.0013903003,0.054430947,0.000017247265,0.00031123718,0.000086638334,0.0000012579952,0.000005436136,0.00030285245],"genre_scores_gemma":[0.9906029,0.000053036973,0.008725904,0.00008976198,0.00031894218,0.0000042814213,0.000004719076,0.00002814778,0.00017227339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990296,0.000039266677,0.00036125464,0.00014513372,0.00024803347,0.00017672744],"domain_scores_gemma":[0.9993068,0.0000045419365,0.00016317282,0.00016544621,0.0001608054,0.00019921822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029916325,0.00013820012,0.0001989527,0.00005571538,0.000026383326,0.000025004429,0.00010745945,0.00006704928,0.000013013946],"category_scores_gemma":[0.000027665808,0.000108506945,0.00009532306,0.000060742896,0.000021028478,0.0000065603554,0.00002270796,0.00007165259,0.0000017725769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042629067,0.000103104525,0.00037383928,0.0000062536906,0.00011721439,0.00008030852,0.00047037879,0.00060061936,0.99651134,0.0000010199739,0.0010110969,0.00029855673],"study_design_scores_gemma":[0.0025624589,0.0009298714,0.000042858013,0.00002461325,0.000031069663,0.00045195277,0.0003395999,0.000046033747,0.9891801,0.0000036771335,0.006245909,0.00014188226],"about_ca_topic_score_codex":0.000004638931,"about_ca_topic_score_gemma":0.0000010314998,"teacher_disagreement_score":0.04714885,"about_ca_system_score_codex":0.000021226957,"about_ca_system_score_gemma":0.00009083664,"threshold_uncertainty_score":0.44247848},"labels":[],"label_agreement":null},{"id":"W4200395955","doi":"10.1016/j.jmb.2021.167420","title":"Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4Hpa","year":2021,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Endonuclease; DNA; Plasmid; Biology; Prophage; Genome editing; Computational biology; Cell biology; Genetics; Chemistry; Gene; Bacteriophage; Escherichia coli","score_opus":0.004603772281090536,"score_gpt":0.29321845285953774,"score_spread":0.2886146805784472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200395955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8620202,0.0095216865,0.12770166,0.00037113644,0.00021201168,0.00009010009,0.000011513196,0.000004676935,0.00006702884],"genre_scores_gemma":[0.9940689,0.00036005754,0.004970924,0.00028617852,0.0001652072,0.00000391032,0.00007153981,0.00002417723,0.000049091184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887776,0.00012661687,0.00037759708,0.00027334926,0.000111001595,0.0002336929],"domain_scores_gemma":[0.99924654,0.000009329105,0.00016259591,0.00019757567,0.0002556808,0.00012825427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016275974,0.00019193429,0.00027364618,0.000070590024,0.00006310594,0.00003292026,0.00010971833,0.00022924233,0.000020705224],"category_scores_gemma":[0.00021053287,0.0001743966,0.00011539599,0.00009526146,0.00007480143,0.0000064952515,0.00013261275,0.0002013015,0.0000013937744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033527438,0.000022332877,0.00014694025,0.000032347856,0.00008596448,0.00011423085,0.00004858991,0.00004482535,0.99693066,0.00035810657,0.00027510824,0.0019073657],"study_design_scores_gemma":[0.00069140765,0.0004911662,0.00018008721,0.00003023015,0.000041270156,0.0007443533,0.000056083743,0.000053491975,0.98752373,0.0012636802,0.008724412,0.00020009263],"about_ca_topic_score_codex":0.000006587966,"about_ca_topic_score_gemma":0.000006304854,"teacher_disagreement_score":0.13204873,"about_ca_system_score_codex":0.000016226548,"about_ca_system_score_gemma":0.000086009626,"threshold_uncertainty_score":0.7111687},"labels":[],"label_agreement":null},{"id":"W4200404753","doi":"10.3791/53552-v","title":"Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Enhancer; Biology; CRISPR; Cas9; Genetics; Gene; Genome editing; Enhancer RNAs; Genome; CRISPR interference; Regulation of gene expression; Gene expression","score_opus":0.018764297673081177,"score_gpt":0.3979786295356905,"score_spread":0.37921433186260933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200404753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94714934,0.0011799765,0.050958514,0.00004347728,0.0004322874,0.00021377385,0.0000042721326,0.0000065448135,0.000011822716],"genre_scores_gemma":[0.99795544,0.00016979687,0.0010702398,0.00010392687,0.00027739347,0.000031260937,0.0000021827989,0.000028488124,0.00036125936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987777,0.00010101383,0.00047162702,0.00020800561,0.000215173,0.00022648534],"domain_scores_gemma":[0.99939525,0.000016234233,0.00014978519,0.000187391,0.000115907904,0.00013542545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002875575,0.00015790998,0.00021639859,0.00014244526,0.000045179844,0.00002200325,0.00014926253,0.0000796533,0.00004646824],"category_scores_gemma":[0.000031805575,0.0001202558,0.00008466923,0.00010995652,0.000009573392,0.000009733272,0.00006847718,0.000072491755,0.000014044366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019468184,0.0002936144,0.0005894796,0.000003122086,0.00009241246,0.0000068176973,0.00037457116,0.0005741098,0.99556655,9.658979e-7,0.00051519286,0.0017884854],"study_design_scores_gemma":[0.0024944334,0.001053696,0.0004530273,0.000027812424,0.000016333548,0.000006555031,0.000703293,0.000069460024,0.99296135,9.74493e-7,0.0020579004,0.00015514427],"about_ca_topic_score_codex":0.0000071960944,"about_ca_topic_score_gemma":0.000012511279,"teacher_disagreement_score":0.05080612,"about_ca_system_score_codex":0.000058113998,"about_ca_system_score_gemma":0.000044376025,"threshold_uncertainty_score":0.4903889},"labels":[],"label_agreement":null},{"id":"W4200424290","doi":"10.1016/j.molcel.2021.12.002","title":"The CRISPR-Cas toolbox and gene editing technologies","year":2021,"lang":"en","type":"review","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":397,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"China Postdoctoral Science Foundation; National Postdoctoral Program for Innovative Talents; Chinese Academy of Sciences; China Association for Science and Technology","keywords":"CRISPR; Biology; Genome editing; Toolbox; Computational biology; Epigenetics; Gene; Cas9; Computer science; Genetics","score_opus":0.010077251134158163,"score_gpt":0.30614277559078457,"score_spread":0.2960655244566264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200424290","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000040151535,0.9894982,0.008921557,0.000049125192,0.0002698846,0.0002711379,0.000015406576,0.000040683793,0.00089384295],"genre_scores_gemma":[0.0002520354,0.99741155,0.0013539946,0.000025921487,0.0001856693,0.00007720181,0.00014961889,0.000072236755,0.00047175004],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986045,0.00006556877,0.0003114003,0.00053058297,0.00013061846,0.00035734955],"domain_scores_gemma":[0.99904525,0.0000288252,0.00011069302,0.00071536214,0.000049613114,0.00005023929],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016663858,0.00036773714,0.0005051723,0.00004435777,0.000144337,0.00010889654,0.0003459008,0.0004312371,0.000002577141],"category_scores_gemma":[0.00012943435,0.00027987748,0.0002973171,0.00012986007,0.00009132443,0.0000011226895,0.00039434418,0.00028183695,0.0000067221986],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[9.519777e-7,0.0000131829875,0.000001180166,0.0015850177,0.0001310398,0.00008870151,0.00000884506,0.000011996941,0.010353597,0.00006195918,0.001455955,0.9862876],"study_design_scores_gemma":[0.000072065515,0.000035172397,2.1693222e-7,0.00034707336,0.00018263976,0.00007785081,0.0000672912,0.000004658941,0.0787477,0.000010711386,0.9201688,0.00028578323],"about_ca_topic_score_codex":0.0000025211016,"about_ca_topic_score_gemma":0.0000036405252,"teacher_disagreement_score":0.9860018,"about_ca_system_score_codex":0.000014119556,"about_ca_system_score_gemma":0.00010462266,"threshold_uncertainty_score":0.9999653},"labels":[],"label_agreement":null},{"id":"W4200468047","doi":"10.1158/1535-7163.targ-21-cc04-01","title":"Abstract CC04-01: First-in-human biomarker-driven phase I TRESR trial of ataxia telangiectasia and Rad3-related inhibitor (ATRi) RP-3500 in patients (pts) with advanced solid tumors harboring synthetic lethal (SL) genomic alterations","year":2021,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Zygosity; Germline; Medicine; Internal medicine; Neutropenia; Biomarker; Cancer research; Oncology; Biology; Genetics; Chemotherapy; Gene","score_opus":0.010232009975896364,"score_gpt":0.30269688500943903,"score_spread":0.2924648750335427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200468047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99521923,0.0034270538,0.0005715316,0.000059167927,0.0001365536,0.00046370577,0.000058331112,0.0000105294475,0.0000538754],"genre_scores_gemma":[0.9989832,0.00036464309,0.0003137328,0.000035039342,0.000041294763,0.00006111917,0.00013193986,0.000053763764,0.000015233123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985775,0.000053017247,0.00045365997,0.00044177118,0.00016422075,0.00030987913],"domain_scores_gemma":[0.9993803,0.00001427901,0.00012773904,0.00034386726,0.00006247373,0.000071356444],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000084589126,0.000252782,0.0003068326,0.00011543685,0.00005624197,0.000026458167,0.00012555644,0.0001405171,0.000015123902],"category_scores_gemma":[0.000013371167,0.00026017352,0.00008449062,0.0001984716,0.0000706397,0.000008866859,0.0000621891,0.00016071806,4.4848167e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001662736,0.00041990302,0.0030247392,0.00006581814,0.0001710031,0.000059802453,0.0002092764,0.010661619,0.9772184,0.0000071427507,0.0000028685513,0.00649673],"study_design_scores_gemma":[0.043939203,0.0010468344,0.018638415,0.00026745035,0.0001178093,0.000011081816,0.00008539345,0.0013257628,0.9331492,0.00001535555,0.0008773998,0.0005260945],"about_ca_topic_score_codex":0.000046523044,"about_ca_topic_score_gemma":0.0002405665,"teacher_disagreement_score":0.04406916,"about_ca_system_score_codex":0.00006669772,"about_ca_system_score_gemma":0.00011369411,"threshold_uncertainty_score":0.99998504},"labels":[],"label_agreement":null},{"id":"W4200480423","doi":"10.1016/j.ymthe.2021.12.006","title":"Anti-Cas9 immunity: A formidable challenge for muscle genome editing","year":2021,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health","keywords":"CRISPR; Genome editing; Duchenne muscular dystrophy; Dystrophin; Cas9; Genetic enhancement; Biology; Nuclease; Utrophin; Immune system; Acquired immune system; Gene; Computational biology; Bioinformatics; Genetics; Medicine","score_opus":0.0166189486294856,"score_gpt":0.2796103208449728,"score_spread":0.2629913722154872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200480423","genre_codex":"methods","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21257412,0.22204594,0.29524705,0.25379607,0.004281885,0.0055455565,0.00086615817,0.00030926638,0.005333954],"genre_scores_gemma":[0.18627277,0.021278948,0.0126569485,0.7138238,0.030315945,0.0021033734,0.02403704,0.001573808,0.007937381],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99812895,0.00006799107,0.00030315501,0.00064452394,0.00021533124,0.00064005837],"domain_scores_gemma":[0.9987481,0.000017885302,0.000115049246,0.0008925684,0.00016384147,0.00006252987],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018768423,0.00045055282,0.00043380138,0.000084597705,0.00013538962,0.0000808789,0.0004171317,0.0008534162,0.000049138536],"category_scores_gemma":[0.000035740562,0.00048800636,0.00044915907,0.000094546864,0.000039597733,0.0000030341785,0.00013380994,0.0005526692,0.0000068781005],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013483955,0.000051922725,0.000002392425,0.000189668,0.00037550204,0.0001576951,0.000074024436,0.00023350146,0.9407955,0.0000077656,0.052728422,0.0053701247],"study_design_scores_gemma":[0.0006708214,0.0002325706,0.000015713138,0.000033329015,0.000029019095,0.000021502574,0.00003212831,0.000041777534,0.19202073,0.000053225136,0.8063995,0.0004496564],"about_ca_topic_score_codex":0.000012684859,"about_ca_topic_score_gemma":0.0000040846785,"teacher_disagreement_score":0.7536711,"about_ca_system_score_codex":0.000024879808,"about_ca_system_score_gemma":0.00009474051,"threshold_uncertainty_score":0.9997572},"labels":[],"label_agreement":null},{"id":"W4200519472","doi":"10.1021/acsagscitech.1c00243","title":"Evaluation of Factors Affecting <i>In Planta</i> Gene Editing Efficiency in Wheat (<i>Triticum aestivum</i> L.)","year":2021,"lang":"en","type":"article","venue":"ACS Agricultural Science & Technology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Western Grains Research Foundation","keywords":"Biology; RNA editing; Genome editing; Guide RNA; Gene; Genetically modified crops; Biotechnology; Computational biology; CRISPR; Genetics; Transgene; Gene expression","score_opus":0.009184281228489003,"score_gpt":0.2795696470317962,"score_spread":0.2703853658033072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200519472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976727,0.0011526109,0.00036345562,0.00013183245,0.00019468747,0.00016579509,0.000003893516,0.000018254055,0.00029678096],"genre_scores_gemma":[0.9995443,0.000047850088,0.00030902974,0.000009368393,0.000046510588,0.000011517392,0.000018844816,0.0000046325126,0.000007944222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851453,0.000040860614,0.0002493232,0.00042739176,0.0003784907,0.00038942683],"domain_scores_gemma":[0.99937886,0.000018301853,0.00006602281,0.00019238207,0.00030706162,0.000037399932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008408452,0.00013027147,0.00015953096,0.00020997153,0.00007194456,0.000012800257,0.00027301032,0.00015774481,0.0000027452807],"category_scores_gemma":[0.00084083324,0.00010318039,0.000032035972,0.0017903311,0.00018114048,0.000013005923,0.00018662134,0.00014423316,7.766971e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000011531577,0.00003722701,0.020234548,0.0000059962586,0.0000024785786,0.000003518185,0.0000812735,0.006417821,0.97199506,0.000023225268,0.0000068432932,0.0011908686],"study_design_scores_gemma":[0.00031929705,0.0000654313,0.10280221,0.000035616282,0.000011516708,0.000055715635,0.0014412189,0.00029231733,0.8948043,0.00002938203,0.00002060549,0.00012241541],"about_ca_topic_score_codex":0.00003402016,"about_ca_topic_score_gemma":0.00035008023,"teacher_disagreement_score":0.08256766,"about_ca_system_score_codex":0.00008298912,"about_ca_system_score_gemma":0.0001468913,"threshold_uncertainty_score":0.4207574},"labels":[],"label_agreement":null},{"id":"W4205189521","doi":"10.2478/ebtj-2019-0006","title":"Future Biotechnology","year":2019,"lang":"en","type":"article","venue":"The EuroBiotech Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Biotechnology; Industrial biotechnology; Engineering ethics; Engineering; Biology","score_opus":0.003324636079971239,"score_gpt":0.24599938357983658,"score_spread":0.24267474749986534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205189521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778242,0.0025840765,0.011700891,0.004846712,0.0013885029,0.00012536337,0.0000027883616,0.000029006509,0.0014984477],"genre_scores_gemma":[0.99534106,0.0011027587,0.0006428904,0.00038013168,0.001093569,0.0000010577619,0.000003737201,0.00002240247,0.001412405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994312,0.000028944592,0.00012059013,0.00013616384,0.0000765289,0.00020657324],"domain_scores_gemma":[0.99953705,0.000004257583,0.000045195666,0.0003458145,0.000026495414,0.00004119509],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020948127,0.000101760685,0.0000770542,0.000037356214,0.0000843852,0.000028058468,0.00034970837,0.00015807207,0.0000782896],"category_scores_gemma":[0.000015514059,0.000067496665,0.00007759579,0.00008425864,0.00003498396,0.0000015304363,0.00010044395,0.000352211,0.00010623005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001582448,0.000008203839,0.00009678557,0.000003126358,0.000025103074,0.0000033434276,0.000018800425,0.00035578138,0.98984075,0.00015448115,0.0043316833,0.005146109],"study_design_scores_gemma":[0.00025435534,0.00016420677,0.000802761,0.0000057470666,0.0000076030888,0.00091347983,0.00009465311,0.000038445705,0.5161251,0.000065465756,0.48141903,0.000109189124],"about_ca_topic_score_codex":7.51047e-7,"about_ca_topic_score_gemma":0.0000011995146,"teacher_disagreement_score":0.47708735,"about_ca_system_score_codex":0.0000060513516,"about_ca_system_score_gemma":0.000023805896,"threshold_uncertainty_score":0.2752434},"labels":[],"label_agreement":null},{"id":"W4205275020","doi":"10.1089/crispr.2021.0128","title":"High-Throughput Imaging of CRISPR- and Recombinant Adeno-Associated Virus–Induced DNA Damage Response in Human Hematopoietic Stem and Progenitor Cells","year":2022,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal","funders":"","keywords":"CRISPR; Genome editing; Cas9; Adeno-associated virus; Biology; Genetic enhancement; Computational biology; Genome; Gene; Recombinant DNA; Genetics; Vector (molecular biology)","score_opus":0.009691495959859733,"score_gpt":0.2812805686757335,"score_spread":0.27158907271587374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205275020","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996908,0.0018924092,0.00027787843,0.00040838894,0.00029602027,0.00018446417,0.000014973992,0.00000727187,0.0000105664885],"genre_scores_gemma":[0.9994622,0.00016014773,0.000086017055,0.000066984256,0.00006831547,0.000015106949,0.0000047281455,0.000031607276,0.00010492016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984687,0.0004202745,0.00038848,0.0002352538,0.00019514043,0.0002921692],"domain_scores_gemma":[0.9993928,0.000047301644,0.00017860932,0.000245738,0.000050179162,0.00008536284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013222558,0.00017102427,0.00023275254,0.00009476096,0.00034955537,0.000048759746,0.00023129712,0.00005452228,0.000023185985],"category_scores_gemma":[0.000042854026,0.00014655448,0.00006245157,0.0001240954,0.00007231658,0.00000762061,0.00030878728,0.0003787902,3.711499e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023265996,0.00009093081,0.0010268717,0.00001986502,0.00004054171,0.000035427238,0.00094624865,0.00015927592,0.9967002,0.000015473363,0.00047776033,0.00025473483],"study_design_scores_gemma":[0.0014769753,0.0005670402,0.012886369,0.000041297353,0.000051611903,0.00035319212,0.0025968514,0.00016918044,0.98086745,0.00018713885,0.0005699562,0.00023296436],"about_ca_topic_score_codex":0.000044870805,"about_ca_topic_score_gemma":0.000014403179,"teacher_disagreement_score":0.015832787,"about_ca_system_score_codex":0.000043673674,"about_ca_system_score_gemma":0.00005627384,"threshold_uncertainty_score":0.5976318},"labels":[],"label_agreement":null},{"id":"W4205690438","doi":"10.1200/jco.2022.40.4_suppl.tps622","title":"Phase 1b expansion study of CX-5461 in patients with solid tumors and <i>BRCA2 </i>and/or <i>PALB2</i> mutation.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; PALB2; Synthetic lethality; DNA repair; PARP inhibitor; Olaparib; Cancer research; Population; Oncology; BRCA mutation; Carcinogenesis; Cancer; Genome instability; Germline mutation; BRCA2 Protein; Prostate cancer; Internal medicine; Mutation; Ovarian cancer; DNA damage; Genetics; Poly ADP ribose polymerase; Biology; Polymerase; Gene; DNA","score_opus":0.0278695928459738,"score_gpt":0.42471991768904405,"score_spread":0.39685032484307026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205690438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990862,0.00027613962,0.00016690342,0.000089397014,0.00018779834,0.00016089485,0.0000044984727,0.0000010687198,0.00002709548],"genre_scores_gemma":[0.99913836,0.000097765325,0.00045485405,0.0001865596,0.00008616695,0.000005491922,0.000004359638,0.000009509423,0.000016950433],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984425,0.00019665278,0.0009287862,0.00015348253,0.0001715908,0.00010704204],"domain_scores_gemma":[0.9990717,0.00014184357,0.0004912895,0.000099289195,0.000100540696,0.0000953115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008299415,0.00008388031,0.00046299756,0.000053438325,0.0000338425,0.0000033920355,0.00009198289,0.000070965056,0.000009765144],"category_scores_gemma":[0.00030663415,0.00006168725,0.00004702818,0.000073489966,0.000058617843,0.000004535571,0.00011120117,0.00026886474,7.3917825e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.035755582,0.052611474,0.65569973,0.000098181416,0.0006669171,0.00067323266,0.002594032,0.009295564,0.016335405,0.000009974743,0.0015190367,0.22474086],"study_design_scores_gemma":[0.104668684,0.2934769,0.5834582,0.000052146082,0.00022973395,0.00025191027,0.0045136265,0.00041647663,0.0035323831,0.00004617881,0.008990636,0.00036314558],"about_ca_topic_score_codex":0.0000070286,"about_ca_topic_score_gemma":0.00004454849,"teacher_disagreement_score":0.24086542,"about_ca_system_score_codex":0.0000120383165,"about_ca_system_score_gemma":0.00018682503,"threshold_uncertainty_score":0.2515533},"labels":[],"label_agreement":null},{"id":"W4205797796","doi":"10.1002/alz.058710","title":"Insertion of the Icelandic mutation (A673T) in the <i>APP</i> gene using the CRISPR/Cas9 base editing and Prime editing technologies, a preventive treatment for Alzheimer?","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Mutation; Genome editing; Genetics; Gene; Amyloid precursor protein; Biology; Exon; Cas9; Gene mutation; Molecular biology; Alzheimer's disease; Medicine; Disease","score_opus":0.021742926027836097,"score_gpt":0.3010779164214963,"score_spread":0.27933499039366017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205797796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8771631,0.107315876,0.013553479,0.0006852286,0.0003103958,0.0008866986,0.000035422207,0.00001698252,0.000032793607],"genre_scores_gemma":[0.99688214,0.00018717932,0.0024893156,0.00008042127,0.00017237314,0.000102146965,0.00006835073,0.000016202173,0.0000018913059],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908614,0.0000903776,0.00024715345,0.00025761809,0.000115921146,0.0002027934],"domain_scores_gemma":[0.99942213,0.00004414148,0.00013535991,0.00031556448,0.00006888471,0.00001391126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027680382,0.00014522724,0.00011542741,0.000025756437,0.00017372744,0.00002903657,0.0001545446,0.00008574409,0.0000025249137],"category_scores_gemma":[0.00006589795,0.0000894405,0.000088067354,0.00014572244,0.000066590306,0.000007739726,0.00011324339,0.000073883646,1.7824453e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038674465,0.00014412733,0.0036905408,0.000016595255,0.0031841942,0.0000068270497,0.0011287052,0.0010039028,0.9303192,0.000051168245,0.00026230785,0.06015378],"study_design_scores_gemma":[0.0005564445,0.00010430754,0.0016830179,0.000026049769,0.0025842434,0.00003610518,0.0019395314,0.0017580636,0.98951745,0.000068560745,0.0016230239,0.00010320684],"about_ca_topic_score_codex":0.00007359989,"about_ca_topic_score_gemma":0.00015236251,"teacher_disagreement_score":0.11971899,"about_ca_system_score_codex":0.0000060322386,"about_ca_system_score_gemma":0.000055669523,"threshold_uncertainty_score":0.3647278},"labels":[],"label_agreement":null},{"id":"W4206018206","doi":"10.20944/preprints202201.0265.v1","title":"CRISPR Therapeutics for Duchenne Muscular Dystrophy","year":2022,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"University of Alberta","keywords":"CRISPR; Genome editing; Duchenne muscular dystrophy; Dystrophin; Biology; Genetics; Gene; Muscular dystrophy; Computational biology; Guide RNA; mdx mouse; Bioinformatics","score_opus":0.07264486298437298,"score_gpt":0.386594939776455,"score_spread":0.313950076792082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206018206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9664077,0.0020365482,0.02754346,0.0002568465,0.0013449666,0.001055548,0.00016972334,0.00007853153,0.0011066583],"genre_scores_gemma":[0.9932637,0.00072228885,0.0018079525,0.00024690622,0.0006746921,0.00077753846,0.0006589401,0.00011956664,0.001728411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977481,0.000071740724,0.0003998504,0.0011006418,0.00023050256,0.00044917015],"domain_scores_gemma":[0.9979513,0.00001974293,0.00015211373,0.0016205546,0.00013945583,0.00011682115],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041706234,0.00042214384,0.00035237506,0.0000816522,0.00013886874,0.000022704577,0.0007610701,0.00039959908,0.00034868854],"category_scores_gemma":[0.000099498815,0.00048107276,0.0004801684,0.000067446614,0.00005644911,0.0000019680963,0.0020844266,0.0005332792,0.000038413255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019152924,0.0002158061,0.032449666,0.000494804,0.0008924274,0.000008832916,0.00030028468,0.030000305,0.93364733,0.00015262859,0.0004123577,0.0012340014],"study_design_scores_gemma":[0.0007230037,0.00013095346,0.022843296,0.000028794135,0.00022086196,0.000010364749,0.00012609478,0.00047940869,0.5226807,0.0004989902,0.45146203,0.0007955327],"about_ca_topic_score_codex":0.0000337352,"about_ca_topic_score_gemma":0.000006013998,"teacher_disagreement_score":0.45104966,"about_ca_system_score_codex":0.000057156813,"about_ca_system_score_gemma":0.00014009948,"threshold_uncertainty_score":0.9997641},"labels":[],"label_agreement":null},{"id":"W4206126535","doi":"10.3389/fpls.2021.774146","title":"The CRISPR/Cas9-Mediated Modulation of SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE 8 in Alfalfa Leads to Distinct Phenotypic Outcomes","year":2022,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Beef Cattle Research Council","keywords":"Biology; Allele; Mutant; Medicago sativa; Raceme; Lotus japonicus; Phenotype; Drought tolerance; Gene; Perennial plant; Genetics; CRISPR; Genotype; Inflorescence; Botany","score_opus":0.0071917408521046,"score_gpt":0.2580333295736253,"score_spread":0.2508415887215207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206126535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886303,0.0001252406,0.010006907,0.00013534907,0.00058818096,0.00039992091,0.000052516312,0.0000059460867,0.000055654175],"genre_scores_gemma":[0.9977714,0.0000058579767,0.0018941099,0.000020809342,0.000013731208,0.00007665654,0.000042531854,0.0000076096617,0.00016729248],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988494,0.00003941495,0.00022678242,0.00030083972,0.00028222782,0.000301354],"domain_scores_gemma":[0.99961966,0.000013428214,0.00005635513,0.00024005696,0.000020478923,0.000050028077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006808343,0.00010002282,0.00012328668,0.00015447171,0.00017021132,0.000019141256,0.0004143175,0.000029213721,0.000002317172],"category_scores_gemma":[0.00017945675,0.00008393988,0.000026246624,0.0005017341,0.000103162325,0.000006711782,0.00021635265,0.0001097856,6.686497e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007676365,0.000048158963,0.20365374,0.000015457432,0.000005012052,0.0000049623186,0.00035779795,0.01190662,0.7806518,0.00002551498,0.00045381256,0.0028003482],"study_design_scores_gemma":[0.0016150416,0.00074219174,0.52634895,0.00007523016,0.000012119231,0.000021317805,0.0018510435,0.062797084,0.3942135,0.00021773404,0.011282906,0.000822858],"about_ca_topic_score_codex":0.000031717253,"about_ca_topic_score_gemma":0.00008303277,"teacher_disagreement_score":0.3864383,"about_ca_system_score_codex":0.00006549954,"about_ca_system_score_gemma":0.00007672503,"threshold_uncertainty_score":0.3422969},"labels":[],"label_agreement":null},{"id":"W4206238555","doi":"10.1016/j.molcel.2021.12.026","title":"CRISPR-based genome editing through the lens of DNA repair","year":2022,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"Genome editing; DNA repair; CRISPR; Recombinase; Transposase; DNA; Genome; Nucleotide excision repair; DNA damage","score_opus":0.007107046487407899,"score_gpt":0.24720928223716665,"score_spread":0.24010223574975875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206238555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87699896,0.00557945,0.10558477,0.00058217853,0.00039834363,0.00037717042,0.00006351905,0.000052819705,0.010362774],"genre_scores_gemma":[0.99694824,0.000016919372,0.0019079125,0.0006536232,0.00010411402,0.00003853996,0.00008037188,0.00003184077,0.00021841157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907774,0.00007256479,0.00018552812,0.00025398805,0.0001930617,0.00021714917],"domain_scores_gemma":[0.99937063,0.000009486576,0.000066589244,0.00049221807,0.000035718673,0.000025377673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001675489,0.00012407482,0.000106883126,0.000021988932,0.000109589644,0.0000066515668,0.00024885024,0.000043325028,0.00007074536],"category_scores_gemma":[0.000022271704,0.000114509065,0.00019235334,0.000112621936,0.000044122782,0.0000012664188,0.00020051158,0.00012440108,0.0000025995057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012058999,0.000043744392,0.000055633136,0.000028989414,0.000023779428,0.000009958613,0.000110892994,0.04560531,0.95322126,0.00007411683,0.00076219364,0.0000520499],"study_design_scores_gemma":[0.00026907385,0.00018269691,0.000103220176,0.0000020336945,0.000025696689,0.000004453653,0.00022168765,0.00051616534,0.79588866,0.000029932004,0.2026274,0.00012894919],"about_ca_topic_score_codex":0.000019511095,"about_ca_topic_score_gemma":0.000002812415,"teacher_disagreement_score":0.20186521,"about_ca_system_score_codex":0.000012323262,"about_ca_system_score_gemma":0.000056242778,"threshold_uncertainty_score":0.4669544},"labels":[],"label_agreement":null},{"id":"W4206320346","doi":"10.3109/08910600903495053","title":"New evidence links CaMV 35S promoter to HIV transcription","year":2009,"lang":"en","type":"article","venue":"Microbial Ecology in Health and Disease","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Transcription (linguistics); Transgene; Human immunodeficiency virus (HIV); Promoter; Biology; Virology; Genetics; Computational biology; Gene; Gene expression","score_opus":0.009347667317951494,"score_gpt":0.30364875710237554,"score_spread":0.29430108978442404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206320346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737985,0.0034992055,0.005285209,0.016790174,0.00016690925,0.00041937412,0.000013130929,0.000012016838,0.000015437916],"genre_scores_gemma":[0.98844606,0.00036748996,0.0012454998,0.009384904,0.0001847895,0.000009833223,0.000049183913,0.0000069991843,0.00030522625],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99916995,0.000038657377,0.00019295469,0.00028076468,0.000029968123,0.00028768383],"domain_scores_gemma":[0.99916345,0.000006046628,0.0000213363,0.00013330427,0.000014379533,0.0006615054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010693762,0.00010312487,0.00011727923,0.000052373995,0.000044277767,0.0000109748835,0.000067941495,0.000120937744,0.00001606098],"category_scores_gemma":[0.00010200851,0.000109905464,0.00002859665,0.000057319146,0.00001346007,0.000003396635,0.000017808317,0.00009933056,0.000009930411],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013508212,0.00018988243,0.021757089,0.00030624267,0.000010486569,0.00003616511,0.00071509735,0.0013361018,0.91116697,0.00006714453,0.031075098,0.031988926],"study_design_scores_gemma":[0.0049665296,0.005063767,0.85742116,0.00052019814,0.000047704758,0.00008729124,0.000130349,0.0004023941,0.029288521,0.00076909206,0.10007663,0.0012263473],"about_ca_topic_score_codex":0.000036217076,"about_ca_topic_score_gemma":0.00018014474,"teacher_disagreement_score":0.88187844,"about_ca_system_score_codex":0.000021408663,"about_ca_system_score_gemma":0.0003382451,"threshold_uncertainty_score":0.44818148},"labels":[],"label_agreement":null},{"id":"W4206565140","doi":"10.1017/cbo9780511642364","title":"Gene Transfer and the Ethics of First-in-Human Research","year":2009,"lang":"en","type":"book","venue":"Cambridge University Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Variety (cybernetics); Psychological intervention; Engineering ethics; Informed consent; Disadvantaged; Medical research; Inclusion (mineral); Clinical trial; Ethical issues; Gene transfer; Political science; Medicine; Psychology; Alternative medicine; Engineering; Law; Social psychology; Computer science; Biology; Psychiatry; Pathology","score_opus":0.028554721475998003,"score_gpt":0.2952697856375823,"score_spread":0.2667150641615843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206565140","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017452452,0.0025308547,0.0011664483,0.00008519086,0.00004845976,0.0005960293,0.000068628455,0.000010403428,0.9780415],"genre_scores_gemma":[0.08777953,0.0013665622,0.00004400064,0.000027348357,0.00011662945,0.0000012646182,0.00006067289,0.000023438653,0.9105806],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990225,0.00014160278,0.0001359224,0.00029982033,0.0001935733,0.00020657363],"domain_scores_gemma":[0.99932176,0.00007951556,0.000025106649,0.00039208017,0.00012582028,0.000055706307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000553733,0.00015781981,0.00022957772,0.00009652944,0.00012860041,0.000011453975,0.00032647746,0.00045763128,3.9176854e-7],"category_scores_gemma":[0.000026921363,0.00015023144,0.0000972487,0.000013597647,0.0004881778,0.000001140908,0.00017021618,0.00066012423,1.5278137e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002739676,0.00017199724,0.00008985025,0.0026273604,0.00094426103,0.0003730154,0.0030992841,0.000802154,0.12604545,0.70146406,0.15793231,0.0037106038],"study_design_scores_gemma":[0.0022306538,0.00017372727,0.00013610307,0.000152982,0.00007943636,0.000011643474,0.000072389455,0.000049068083,0.07218246,0.000018972147,0.9246094,0.00028314017],"about_ca_topic_score_codex":0.00011770684,"about_ca_topic_score_gemma":0.000045085533,"teacher_disagreement_score":0.76667714,"about_ca_system_score_codex":0.000031095733,"about_ca_system_score_gemma":0.000113956216,"threshold_uncertainty_score":0.6126261},"labels":[],"label_agreement":null},{"id":"W4206637805","doi":"10.3410/f.6012958.793485603","title":"Faculty Opinions recommendation of The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA.","year":2013,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Plasmid; Biology; Extrachromosomal DNA; Bacteriophage; Trans-activating crRNA; Genetics; DNA; Gene; Cas9; Genome; Microbiology; Horizontal gene transfer; Computational biology; Escherichia coli","score_opus":0.013263861811690128,"score_gpt":0.32336687638745965,"score_spread":0.3101030145757695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206637805","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000056299286,0.0020012192,0.00006368261,0.02817202,0.0016139491,0.001109748,0.9669424,0.000015500867,0.000025159636],"genre_scores_gemma":[0.00035410956,0.00051522296,0.00024929925,0.00061558146,0.00046565183,0.00015559798,0.99711764,0.000028990651,0.00049789535],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972008,0.0002912358,0.0011068686,0.0005492046,0.0005657476,0.00028616856],"domain_scores_gemma":[0.9959745,0.000037874845,0.00084635254,0.0013516186,0.0016149741,0.00017469203],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006026844,0.00045122928,0.0006345425,0.00010827948,0.00019616442,0.00012920861,0.0011252679,0.00066207146,0.00012120374],"category_scores_gemma":[0.0016029452,0.0002706568,0.00044600046,0.00050127844,0.00026382142,0.000027892913,0.000769794,0.000498202,0.0000127940075],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012740862,0.00007592112,0.0000032143219,0.005126557,0.00012100483,7.606555e-8,0.00004117885,1.8678955e-7,0.0010708694,0.000036363595,0.9928684,0.0006434688],"study_design_scores_gemma":[0.00049608847,0.000100557765,0.003452057,0.00426363,0.0001294881,0.00005439851,0.00003744074,0.0000071955824,0.0035867325,0.0000013102474,0.9876019,0.0002691951],"about_ca_topic_score_codex":0.00004113781,"about_ca_topic_score_gemma":0.0000053102845,"teacher_disagreement_score":0.03017523,"about_ca_system_score_codex":0.00004252814,"about_ca_system_score_gemma":0.00020456499,"threshold_uncertainty_score":0.99997455},"labels":[],"label_agreement":null},{"id":"W4206955199","doi":"10.1016/j.crmeth.2021.100150","title":"Construction of Strand-seq libraries in open nanoliter arrays","year":2022,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Computer science; World Wide Web","score_opus":0.015266127154697547,"score_gpt":0.35444915824215206,"score_spread":0.3391830310874545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206955199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78098637,0.0030878312,0.18394175,0.00004301049,0.0009911371,0.0004115907,0.000010849614,0.0000133476,0.03051411],"genre_scores_gemma":[0.7380554,0.000050270344,0.26091602,0.00003052433,0.0000363961,0.000037260375,0.000043490963,0.000015668027,0.00081495754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991582,0.0001238724,0.0002902962,0.00023600415,0.000072982235,0.00011863753],"domain_scores_gemma":[0.9995352,0.00001404769,0.000108466076,0.00029292091,0.000017832952,0.00003152951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006403791,0.000079212106,0.00014515196,0.000047628673,0.000039860457,0.000017486635,0.00013307767,0.00004598708,0.000100539684],"category_scores_gemma":[0.00003374368,0.00008481606,0.000048952228,0.000104823914,0.000039378916,0.000005098095,0.00028659578,0.00008146716,7.1578874e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038060392,0.00004438341,0.003916458,0.000035615874,0.00001394116,0.000029030392,0.00022358146,0.0045815194,0.9797562,0.00016607204,0.00025506484,0.010940104],"study_design_scores_gemma":[0.00019726451,0.00008112532,0.0005546859,0.0000039708098,0.000007814551,0.00013918043,0.00036829515,0.000093272785,0.95142764,0.002249957,0.044769835,0.00010695239],"about_ca_topic_score_codex":0.000021406839,"about_ca_topic_score_gemma":0.000002015079,"teacher_disagreement_score":0.07697425,"about_ca_system_score_codex":0.0000074654104,"about_ca_system_score_gemma":0.00007663249,"threshold_uncertainty_score":0.34586987},"labels":[],"label_agreement":null},{"id":"W4206986373","doi":"10.3389/fgene.2021.591543","title":"Fluoride-Controlled Riboswitch-Based Dampening of Gene Expression for Cloning Potent Promoters","year":2022,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Armand-Frappier Foundation","keywords":"Bioreporter; Promoter; Reporter gene; Riboswitch; Biology; Multiple cloning site; Luciferase; Plasmid; Gene; Gene expression; Genetics; Computational biology; Expression vector; Recombinant DNA; Non-coding RNA; Transfection","score_opus":0.006026119057541279,"score_gpt":0.2582736493339288,"score_spread":0.2522475302763875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206986373","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.459663,0.0034767485,0.535291,0.000040947874,0.0007783443,0.0006614381,0.000039289014,0.0000091192915,0.000040078583],"genre_scores_gemma":[0.80702794,0.00004819823,0.19226328,0.000051469677,0.00009698778,0.0002529084,0.00013408902,0.0000377075,0.000087422195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869287,0.000060373444,0.00038670687,0.00035286302,0.00019695601,0.00031023382],"domain_scores_gemma":[0.9994006,0.000015744137,0.00013066428,0.00034224772,0.000050070936,0.00006063033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035432944,0.00017493496,0.00030499435,0.00013320192,0.000105061285,0.000009460839,0.00026797372,0.000082724466,0.0000065543763],"category_scores_gemma":[0.00006461491,0.00019196265,0.00016316076,0.000116392366,0.000033391712,0.0000016433326,0.00011460451,0.00011170344,1.01288336e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055957184,0.00006170975,0.00676664,0.00003830946,0.000036223788,0.0000020171242,0.00010656376,0.23076458,0.7581007,0.0000016458639,0.0012732748,0.0022887418],"study_design_scores_gemma":[0.004835488,0.0004959239,0.000551596,0.000017850918,0.00003538726,0.0000032691498,0.00028604307,0.043229084,0.94482446,0.00004660899,0.005431013,0.00024328651],"about_ca_topic_score_codex":0.0000036039787,"about_ca_topic_score_gemma":0.0000018242432,"teacher_disagreement_score":0.34736493,"about_ca_system_score_codex":0.000041579777,"about_ca_system_score_gemma":0.000089827445,"threshold_uncertainty_score":0.782801},"labels":[],"label_agreement":null},{"id":"W4207015623","doi":"10.1089/nat.2021.29004.ots","title":"17th Annual Meeting of the Oligonucleotide Therapeutics Society: A Tribute to Bob Letsinger, Progress in <i>N</i>  = 1 Treatments, and Successful First In-Humans CRISPR Trials","year":2022,"lang":"en","type":"article","venue":"Nucleic Acid Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; McGill University","funders":"","keywords":"Tribute; Library science; Medicine; History; Art history; Computer science","score_opus":0.017288943340266833,"score_gpt":0.3120626520839123,"score_spread":0.2947737087436455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4207015623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876786,0.0086803185,0.00023310288,0.0023083182,0.00020444908,0.00067339564,0.00014105174,0.000015276013,0.00006550667],"genre_scores_gemma":[0.9970232,0.0008808392,0.00067303114,0.0011080651,0.000078975536,0.00009476495,0.000018611037,0.00005348076,0.00006901641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815875,0.00022720435,0.0005583123,0.0003949347,0.00026345675,0.00039734194],"domain_scores_gemma":[0.9992291,0.000057931004,0.00017525983,0.00043443352,0.000048671467,0.000054633703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008700144,0.0002600265,0.00041031704,0.00006868633,0.00019491065,0.00003075226,0.00038833916,0.00011531347,0.000009636175],"category_scores_gemma":[0.000022793922,0.00021924506,0.0001881567,0.00034825053,0.00011167935,0.0000068679956,0.00036987054,0.00022969027,4.6703838e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008239772,0.0011224081,0.30532792,0.00018673,0.001013336,0.000013133722,0.015927276,0.005133922,0.6278862,0.0000915386,0.0012725155,0.041201048],"study_design_scores_gemma":[0.009454192,0.0020278294,0.11461922,0.00021346903,0.00060058123,0.000041210325,0.010408505,0.0025284616,0.52078396,0.00027016352,0.33762214,0.0014302658],"about_ca_topic_score_codex":0.000045168814,"about_ca_topic_score_gemma":0.00020538158,"teacher_disagreement_score":0.3363496,"about_ca_system_score_codex":0.00006659308,"about_ca_system_score_gemma":0.00006584813,"threshold_uncertainty_score":0.8940554},"labels":[],"label_agreement":null},{"id":"W4210248179","doi":"10.1002/alz.050660","title":"Development of a therapeutic approach for hereditary diseases with prime editing: A study on Alzheimer's disease","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Genome editing; HEK 293 cells; Sanger sequencing; Mutation; Induced pluripotent stem cell; Biology; Computational biology; Amyloid precursor protein; Molecular biology; Gene; Genetics; CRISPR; Alzheimer's disease; Disease; Medicine; Embryonic stem cell","score_opus":0.023775801697892448,"score_gpt":0.29461774434932875,"score_spread":0.2708419426514363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210248179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56167275,0.3090999,0.12533861,0.00012036881,0.0004981546,0.0026253336,0.00016383677,0.00007016517,0.0004108537],"genre_scores_gemma":[0.98492014,0.000011975071,0.014099495,0.00007936703,0.00020508478,0.00024924107,0.0003902343,0.00003931119,0.0000051233455],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886024,0.00003079717,0.0002388645,0.00042846496,0.00020077679,0.00024085093],"domain_scores_gemma":[0.9993101,0.000011359333,0.000068304566,0.0003809946,0.0001014696,0.00012777765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008196085,0.00020473075,0.00017372702,0.000030379813,0.00008464621,0.00001684128,0.00014161471,0.000039744627,0.000011582231],"category_scores_gemma":[0.000008783809,0.00018115916,0.00008491499,0.000077439276,0.000032035485,0.0000036579377,0.00008339992,0.000043657543,0.000001150047],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004271886,0.019984711,0.10332667,0.00023763816,0.19409093,0.0001677317,0.003864586,0.0054981797,0.28628495,0.00028613763,0.0043319906,0.37765455],"study_design_scores_gemma":[0.003362627,0.0012170505,0.08616983,0.00004314273,0.02391516,0.000009836384,0.0022673912,0.0005538561,0.86692697,0.000020055568,0.014665305,0.0008487527],"about_ca_topic_score_codex":0.0000015808049,"about_ca_topic_score_gemma":0.0000060971697,"teacher_disagreement_score":0.58064204,"about_ca_system_score_codex":0.0000017518494,"about_ca_system_score_gemma":0.0001757524,"threshold_uncertainty_score":0.7387456},"labels":[],"label_agreement":null},{"id":"W4210377497","doi":"10.1101/2022.02.02.478894","title":"Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Chan Zuckerberg Initiative; York University; Defense Advanced Research Projects Agency; National Cancer Institute; National Institutes of Health; Cancer Research Institute","keywords":"CRISPR; Carpool; Computational biology; RNA; Guide RNA; Biology; Gene; Cas9; Genetics; Computer science","score_opus":0.006962885834835533,"score_gpt":0.2175148345692342,"score_spread":0.21055194873439867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210377497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924784,0.0026154742,0.0022527613,0.0000321783,0.0018038445,0.0005644339,0.00016406202,0.00005067569,0.00003818326],"genre_scores_gemma":[0.9971628,0.00011228943,0.0021176785,0.00003520413,0.00032715566,0.000105036794,0.000002604006,0.0001318703,0.00000536813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974852,0.00011314088,0.00056809816,0.00090705714,0.000392783,0.0005337048],"domain_scores_gemma":[0.99852103,0.000022713011,0.00025235422,0.0008397906,0.00020175245,0.00016233878],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045355083,0.0005038941,0.0005323832,0.00019513737,0.00008482005,0.00004425004,0.00049765053,0.00039079503,0.00003371377],"category_scores_gemma":[0.00007395716,0.0005441934,0.0001696275,0.00032391268,0.00011534367,0.0000029757325,0.00037523566,0.00059608236,0.0000016720859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000114233975,0.00028382838,0.0006911869,0.00031868505,0.00008824505,0.00003772184,0.0000407068,0.042018168,0.9562703,0.000044601707,0.000090991816,0.0000013507873],"study_design_scores_gemma":[0.0011201482,0.00030617067,0.0023706823,0.00015583649,0.00006451651,3.211564e-8,0.000022434686,0.0008891007,0.99211454,4.9363786e-7,0.0022905348,0.00066552404],"about_ca_topic_score_codex":0.00009783698,"about_ca_topic_score_gemma":0.0000060250277,"teacher_disagreement_score":0.041129064,"about_ca_system_score_codex":0.00013660327,"about_ca_system_score_gemma":0.00034777485,"threshold_uncertainty_score":0.99970096},"labels":[],"label_agreement":null},{"id":"W4210586290","doi":"10.3390/life12020171","title":"Cell Cycle Stage and DNA Repair Pathway Influence CRISPR/Cas9 Gene Editing Efficiency in Porcine Embryos","year":2022,"lang":"en","type":"article","venue":"Life","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Zygote; Embryo; Biology; CRISPR; Genome editing; Blastocyst; Cas9; Somatic cell; Cell biology; Cell cycle; Somatic cell nuclear transfer; Embryonic stem cell; Embryogenesis; Genetics; Andrology; Gene","score_opus":0.004220010429751007,"score_gpt":0.24210687679555962,"score_spread":0.2378868663658086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210586290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99591684,0.0022030475,0.00099029,0.000059743183,0.0001436425,0.00012933323,0.00003110249,0.000028372186,0.00049763406],"genre_scores_gemma":[0.9985245,0.000051702737,0.00040847473,0.00033388688,0.00016182064,0.000030947864,0.000030961353,0.000019283118,0.0004384605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906254,0.000036401136,0.0002022163,0.0003237148,0.00012901468,0.00024609632],"domain_scores_gemma":[0.9995869,0.000010918241,0.00004563968,0.00024798117,0.000018732291,0.0000898229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022571594,0.000119606564,0.00011418132,0.000050102808,0.00010056816,0.000011748864,0.00011901979,0.00004787818,0.000031574193],"category_scores_gemma":[0.00008361503,0.00013371423,0.0000419921,0.00011928807,0.00002387593,0.000003037844,0.00025615725,0.00013219223,0.0000018769841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019445304,0.000061425555,0.008721062,0.000049681264,0.0000067027295,0.00003056182,0.0002200158,0.038538978,0.9516935,0.000017638527,0.00047006892,0.00017094842],"study_design_scores_gemma":[0.0014393905,0.00052973104,0.03384552,0.0000143204115,0.000013015508,0.000036029047,0.0011941595,0.009575668,0.9201455,0.000013333036,0.03267263,0.0005206609],"about_ca_topic_score_codex":0.000046174595,"about_ca_topic_score_gemma":0.000010569843,"teacher_disagreement_score":0.03220256,"about_ca_system_score_codex":0.0000123983655,"about_ca_system_score_gemma":0.00004717157,"threshold_uncertainty_score":0.5452708},"labels":[],"label_agreement":null},{"id":"W4210616091","doi":"10.1186/s12936-022-04062-4","title":"Articulating ethical principles guiding Target Malaria's engagement strategy","year":2022,"lang":"en","type":"article","venue":"Malaria Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Silicon Valley Community Foundation; Bill and Melinda Gates Foundation","keywords":"Community engagement; Public engagement; Malaria; Gene drive; Best practice; Public relations; Public health; Political science; Engineering ethics; Biology; Engineering; Medicine; Law","score_opus":0.03522053256597432,"score_gpt":0.3141455752815871,"score_spread":0.2789250427156128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210616091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9080416,0.001270721,0.08322349,0.002714378,0.0011405939,0.00023750105,0.00001642646,0.000035917245,0.0033193498],"genre_scores_gemma":[0.9904011,0.000027114133,0.008104716,0.0003318164,0.0006277861,0.000019847472,0.000024444673,0.000030256195,0.00043294748],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984762,0.00023258268,0.00035428975,0.00024898755,0.00031957892,0.00036834728],"domain_scores_gemma":[0.99946797,0.000016919468,0.00010604096,0.00021586388,0.000056207813,0.00013697009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014634131,0.00015478223,0.00013467272,0.00006066836,0.0006164934,0.000101785045,0.00022399417,0.000117210446,0.0007732863],"category_scores_gemma":[0.0001692431,0.00015860813,0.00012214699,0.00009132948,0.00002202284,0.0000034326765,0.00039503674,0.0007718353,0.000004438304],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008317643,0.00006565878,0.0044799442,0.000017627252,0.0001615788,0.000103350045,0.000253136,0.40813404,0.57897633,0.004095836,0.002443045,0.0011862724],"study_design_scores_gemma":[0.0034241732,0.0023798493,0.07967785,0.00005606898,0.0001803062,0.0037603597,0.0034786514,0.05134469,0.24842116,0.001216545,0.6044515,0.0016088499],"about_ca_topic_score_codex":0.0000026264488,"about_ca_topic_score_gemma":0.0000015505849,"teacher_disagreement_score":0.60200846,"about_ca_system_score_codex":0.00004402746,"about_ca_system_score_gemma":0.00010640582,"threshold_uncertainty_score":0.84669423},"labels":[],"label_agreement":null},{"id":"W4210644796","doi":"10.3390/biology11020201","title":"Increasing the Efficiency of Canola and Soybean GMO Detection and Quantification Using Multiplex Droplet Digital PCR","year":2022,"lang":"en","type":"article","venue":"Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Digital polymerase chain reaction; Canola; Biology; Multiplex; Real-time polymerase chain reaction; Genetically modified organism; Duplex (building); Multiplex polymerase chain reaction; Computational biology; Molecular biology; Gene; Biotechnology; Genetics; Polymerase chain reaction; Food science; DNA","score_opus":0.012679309254354777,"score_gpt":0.28883125673995297,"score_spread":0.2761519474855982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210644796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98555386,0.0009844889,0.013228856,0.00002079804,0.00008020706,0.00008255791,0.000020944597,0.0000044256094,0.00002385414],"genre_scores_gemma":[0.99974567,0.000029573988,0.00013080059,0.000013138271,0.00003659003,0.000005384211,0.000025343239,0.000006053301,0.000007443044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995888,0.000047076308,0.00009798613,0.00015039337,0.000027307333,0.00008842019],"domain_scores_gemma":[0.9997982,0.00002077685,0.000042030813,0.00010664046,0.000015518619,0.000016826258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014279781,0.000055934255,0.00006027869,0.000026128464,0.00012712638,0.000008746957,0.000050283576,0.000036690533,0.0000019387169],"category_scores_gemma":[0.00006138092,0.00004698336,0.000016193964,0.000047588688,0.00007954388,0.0000014799385,0.00010848786,0.000043368465,7.58197e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002332291,0.000008870946,0.009306086,0.0000051297816,0.000007868309,1.1984412e-7,0.000060328737,0.00019132429,0.98606396,0.000018993142,0.0000017007716,0.0043123187],"study_design_scores_gemma":[0.00072629034,0.0006360662,0.0423785,0.0000061791075,0.000036050613,0.0003472213,0.0010484449,0.021778442,0.92342246,0.00007828859,0.009244813,0.00029724016],"about_ca_topic_score_codex":0.00014000088,"about_ca_topic_score_gemma":0.000025711222,"teacher_disagreement_score":0.06264147,"about_ca_system_score_codex":0.000006049443,"about_ca_system_score_gemma":0.0000131301185,"threshold_uncertainty_score":0.19159259},"labels":[],"label_agreement":null},{"id":"W4210696891","doi":"10.3390/ijms23031832","title":"CRISPR Therapeutics for Duchenne Muscular Dystrophy","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"University of Alberta; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"CRISPR; Duchenne muscular dystrophy; Dystrophin; Genome editing; Biology; Genetics; Muscular dystrophy; Gene; Guide RNA; mdx mouse; Cas9; Computational biology; Bioinformatics","score_opus":0.04291168171114318,"score_gpt":0.40862953975119376,"score_spread":0.3657178580400506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210696891","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025651287,0.9534841,0.044256486,0.00006820722,0.001610736,0.00017236378,0.00003882782,0.000003054768,0.00010968303],"genre_scores_gemma":[0.000807083,0.9935175,0.0048359586,0.00012934262,0.00056587375,0.000023642157,0.000041681764,0.000030285757,0.00004859614],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983891,0.00007157387,0.0005159148,0.00026338655,0.00057166413,0.00018832569],"domain_scores_gemma":[0.99906784,0.000044131284,0.00044018505,0.00016622568,0.00022071616,0.000060902068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058885687,0.0002162551,0.00041157508,0.00023411808,0.000075032774,0.00008969017,0.0013022517,0.000109653134,0.00003479032],"category_scores_gemma":[0.00010835512,0.00017751056,0.00076632074,0.00013089342,0.000093405426,0.000006105693,0.00016972012,0.00018055813,0.000001112513],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025726844,0.00008498076,0.0000020684458,0.0003844175,0.0011823397,0.00008466088,0.000033039654,0.0015828254,0.005063215,0.00030506306,0.0004389637,0.9908127],"study_design_scores_gemma":[0.00020359247,0.00038388727,5.9694116e-7,0.00023080788,0.00023061557,0.00037445387,0.000032391505,0.000024953475,0.0016117054,0.00008040741,0.9966368,0.0001897643],"about_ca_topic_score_codex":0.0000016781308,"about_ca_topic_score_gemma":5.146401e-7,"teacher_disagreement_score":0.9961979,"about_ca_system_score_codex":0.00004318724,"about_ca_system_score_gemma":0.00037732246,"threshold_uncertainty_score":0.72386706},"labels":[],"label_agreement":null},{"id":"W4210897276","doi":"10.1089/crispr.2021.0085","title":"Insertion of the Icelandic Mutation (A673T) by Prime Editing: A Potential Preventive Treatment for Familial and Sporadic Alzheimer's Disease","year":2022,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute on Aging; Canadian Institutes of Health Research","keywords":"Mutation; Amyloid precursor protein; CRISPR; Genetics; Biology; Population; Gene; Alzheimer's disease; Molecular biology; Disease; Medicine; Pathology","score_opus":0.0074351234387578504,"score_gpt":0.2772743626681504,"score_spread":0.26983923922939257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210897276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812797,0.0046294434,0.012833754,0.00047627385,0.0003670379,0.00031734022,0.000085316584,0.0000027363988,0.000008409887],"genre_scores_gemma":[0.99924165,0.00013971198,0.00006680065,0.00004151328,0.0003185882,0.000035991834,0.000045252276,0.0000112123535,0.000099299636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942744,0.000080964885,0.00014804672,0.00010645342,0.00012287083,0.00011422591],"domain_scores_gemma":[0.99967766,0.000008891692,0.00011701752,0.000114209804,0.00003206223,0.000050190265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001832318,0.00008215318,0.00007116638,0.000014050556,0.00032204832,0.00001492044,0.00010854356,0.000019996938,0.000011380162],"category_scores_gemma":[0.000019714362,0.000052473384,0.00010166721,0.00003500193,0.000040814575,0.0000030395784,0.000056987086,0.000076778124,1.09572e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014871379,0.00036733088,0.0031781653,0.00002768598,0.0006358417,0.000010221978,0.0013356577,0.009391665,0.95200384,0.00003520494,0.007233951,0.024293272],"study_design_scores_gemma":[0.007170366,0.0032290579,0.06450776,0.000045525932,0.0018969345,0.0006545203,0.0030112513,0.008790637,0.8793182,0.001249957,0.029624393,0.0005014085],"about_ca_topic_score_codex":0.000012252186,"about_ca_topic_score_gemma":0.0000024020526,"teacher_disagreement_score":0.07268568,"about_ca_system_score_codex":0.000022106873,"about_ca_system_score_gemma":0.000059684695,"threshold_uncertainty_score":0.24769679},"labels":[],"label_agreement":null},{"id":"W4211123163","doi":"10.1038/s43586-021-00093-4","title":"High-content CRISPR screening","year":2022,"lang":"en","type":"article","venue":"Nature Reviews Methods Primers","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":574,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; University of Toronto","funders":"","keywords":"CRISPR; Computational biology; Trans-activating crRNA; Biology; Drug discovery; Multiplex; Genome editing; High-content screening; Gene; Genetics; Bioinformatics; Cell","score_opus":0.039250689544975764,"score_gpt":0.4228328634316131,"score_spread":0.3835821738866373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4211123163","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005273668,0.33167124,0.6599932,0.00032444007,0.001362814,0.000619972,0.000014352629,0.000034300225,0.0007060036],"genre_scores_gemma":[0.025368115,0.007101409,0.96394145,0.0016523913,0.0003813614,0.00017280225,0.00011283347,0.00005283695,0.0012167755],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99829924,0.0005526431,0.00030461355,0.00041149944,0.00016383415,0.0002681424],"domain_scores_gemma":[0.999255,0.000028601533,0.0001087935,0.00048051536,0.000036236554,0.000090837784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017950365,0.00019851046,0.00031292436,0.00005864822,0.00015726381,0.000012790491,0.00031537775,0.00014868367,0.00012757188],"category_scores_gemma":[0.00033518387,0.00018337583,0.00024395715,0.00019522263,0.000022932125,0.000002186022,0.00029726894,0.00060342567,0.000004184749],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002534049,0.00002114953,0.000068676134,0.00004009155,0.000059118287,0.000002261039,0.000025075751,0.000432907,0.5802688,0.0001688174,0.006425465,0.41246232],"study_design_scores_gemma":[0.00020577224,0.00009101119,0.00029543365,0.000010573472,0.00003994983,0.000022134232,0.00004984031,0.000035400633,0.1935475,0.000019661873,0.8054853,0.00019738456],"about_ca_topic_score_codex":0.000011953351,"about_ca_topic_score_gemma":0.0000012568224,"teacher_disagreement_score":0.79905987,"about_ca_system_score_codex":0.000023353761,"about_ca_system_score_gemma":0.000029284263,"threshold_uncertainty_score":0.7477849},"labels":[],"label_agreement":null},{"id":"W4211219428","doi":"10.1038/s43586-022-00098-7","title":"High-content CRISPR screening","year":2022,"lang":"en","type":"article","venue":"Nature Reviews Methods Primers","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":253,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; University of Toronto","funders":"Common Fund; National Institute of Biomedical Imaging and Bioengineering; National Institute of Diabetes and Digestive and Kidney Diseases; Li Ka Shing Foundation; Canadian Institutes of Health Research; European Commission; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Computational biology; Biology; Trans-activating crRNA; Multiplex; Genome editing; Drug discovery; Gene; Genetics; Bioinformatics","score_opus":0.039250689544975764,"score_gpt":0.4228328634316131,"score_spread":0.3835821738866373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4211219428","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005273668,0.33167124,0.6599932,0.00032444007,0.001362814,0.000619972,0.000014352629,0.000034300225,0.0007060036],"genre_scores_gemma":[0.025368115,0.007101409,0.96394145,0.0016523913,0.0003813614,0.00017280225,0.00011283347,0.00005283695,0.0012167755],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99829924,0.0005526431,0.00030461355,0.00041149944,0.00016383415,0.0002681424],"domain_scores_gemma":[0.999255,0.000028601533,0.0001087935,0.00048051536,0.000036236554,0.000090837784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017950365,0.00019851046,0.00031292436,0.00005864822,0.00015726381,0.000012790491,0.00031537775,0.00014868367,0.00012757188],"category_scores_gemma":[0.00033518387,0.00018337583,0.00024395715,0.00019522263,0.000022932125,0.000002186022,0.00029726894,0.00060342567,0.000004184749],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002534049,0.00002114953,0.000068676134,0.00004009155,0.000059118287,0.000002261039,0.000025075751,0.000432907,0.5802688,0.0001688174,0.006425465,0.41246232],"study_design_scores_gemma":[0.00020577224,0.00009101119,0.00029543365,0.000010573472,0.00003994983,0.000022134232,0.00004984031,0.000035400633,0.1935475,0.000019661873,0.8054853,0.00019738456],"about_ca_topic_score_codex":0.000011953351,"about_ca_topic_score_gemma":0.0000012568224,"teacher_disagreement_score":0.79905987,"about_ca_system_score_codex":0.000023353761,"about_ca_system_score_gemma":0.000029284263,"threshold_uncertainty_score":0.7477849},"labels":[],"label_agreement":null},{"id":"W4212872437","doi":"10.1186/s12896-022-00737-7","title":"An efficient and specific CRISPR-Cas9 genome editing system targeting soybean phytoene desaturase genes","year":2022,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Biology; Phytoene desaturase; CRISPR; Genome editing; Gene; Cas9; Genetics; Genome; Computational biology; Gene silencing","score_opus":0.007166046550000191,"score_gpt":0.2444570798837921,"score_spread":0.2372910333337919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212872437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8890955,0.01090867,0.0989558,0.00009268179,0.00046751363,0.00022612643,0.00004361592,0.00016312477,0.000046958237],"genre_scores_gemma":[0.9847572,0.00012146294,0.01436905,0.000035111967,0.00047607662,0.000052790772,0.00011965866,0.000044717406,0.000023943772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849194,0.000071270486,0.00026379977,0.00061337824,0.00013090609,0.0004287277],"domain_scores_gemma":[0.999298,0.000010172173,0.000089014815,0.0004826356,0.000031372878,0.00008881876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030327964,0.00021726912,0.00019863367,0.00014347746,0.0003523412,0.000027956828,0.00030740592,0.00022351596,0.000018573373],"category_scores_gemma":[0.000023853947,0.00023806453,0.00006255889,0.00017827074,0.00009973644,0.0000023057148,0.0004144454,0.00025054245,0.0000039252313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026197744,0.000039751554,0.0006916636,0.000058320413,0.000017546494,0.000016518317,0.000042406667,0.012636907,0.98447996,0.00037095253,0.00010368483,0.0015160894],"study_design_scores_gemma":[0.00067861145,0.00051024824,0.0015487791,0.000010326583,0.000026132533,0.00041318763,0.004200518,0.011781216,0.9405982,0.000010718213,0.03969744,0.0005246345],"about_ca_topic_score_codex":0.000011841686,"about_ca_topic_score_gemma":0.000011246839,"teacher_disagreement_score":0.09566168,"about_ca_system_score_codex":0.00004163958,"about_ca_system_score_gemma":0.000028169618,"threshold_uncertainty_score":0.97079897},"labels":[],"label_agreement":null},{"id":"W4213036952","doi":"10.1093/nar/gkac142","title":"Spacer2PAM: A computational framework to guide experimental determination of functional CRISPR-Cas system PAM sequences","year":2022,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Joint Genome Institute; National Science Foundation Graduate Research Fellowship Program; Suncor Energy Incorporated; U.S. Department of Energy; David and Lucile Packard Foundation; National Science Foundation","keywords":"CRISPR; Computational biology; Biology; Trans-activating crRNA; Effector; CRISPR interference; Genome editing; Synthetic biology; Genetics; Gene; Cell biology","score_opus":0.03436691995092781,"score_gpt":0.3970631307690581,"score_spread":0.36269621081813025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213036952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8003222,0.00046487537,0.19685528,0.0002458236,0.00025637462,0.00031707418,0.00004456971,0.000020217985,0.0014736367],"genre_scores_gemma":[0.9873157,0.000004023977,0.011849471,0.000045948516,0.00016987017,0.00012656393,0.00006025227,0.000019988714,0.00040814784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984067,0.00013346266,0.00020430959,0.0003015468,0.00070281443,0.00025113084],"domain_scores_gemma":[0.99941397,0.00005169674,0.000032041993,0.00022079164,0.00018849396,0.00009303734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058334536,0.000093337396,0.00010529116,0.00014880464,0.00024767866,0.000023042514,0.00022615542,0.000065538385,0.00022685448],"category_scores_gemma":[0.00010318152,0.000102457736,0.00005924333,0.00027190626,0.0000699099,0.000003696259,0.000372497,0.0001917774,0.000015108728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019564579,0.0001314822,0.0017598133,0.00007407171,0.000037817787,0.000011449017,0.00086997834,0.04385985,0.94118625,0.0020267635,0.007175438,0.0026714674],"study_design_scores_gemma":[0.0010113202,0.0024700235,0.013686544,0.00008660773,0.000015283927,0.00020843184,0.017050553,0.032002144,0.8826948,0.00047942018,0.04972,0.00057491433],"about_ca_topic_score_codex":0.000038364244,"about_ca_topic_score_gemma":0.0000033352585,"teacher_disagreement_score":0.18699358,"about_ca_system_score_codex":0.00014532279,"about_ca_system_score_gemma":0.00012409948,"threshold_uncertainty_score":0.41781053},"labels":[],"label_agreement":null},{"id":"W4213096054","doi":"10.1038/s41434-022-00323-8","title":"CRISPR editing as a therapeutic strategy for Duchenne muscular dystrophy—anti-Cas9 immune response casts its shadow over safety and efficacy","year":2022,"lang":"en","type":"article","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"CRISPR; Duchenne muscular dystrophy; Genome editing; Biology; Genetic enhancement; Cas9; Immune system; Muscular dystrophy; Virology; Genetics; Bioinformatics; Immunology; Gene","score_opus":0.01482409384323293,"score_gpt":0.3080905154608623,"score_spread":0.2932664216176294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213096054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.976953,0.017023524,0.004761741,0.00021320925,0.00029748734,0.0005976652,0.00009250963,0.000029481707,0.000031334614],"genre_scores_gemma":[0.99701333,0.0013224802,0.00032358686,0.0002786453,0.00040254698,0.00011243779,0.000114864495,0.00007312065,0.00035900596],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984752,0.00014512961,0.00028768452,0.0004902138,0.00017754384,0.00042425937],"domain_scores_gemma":[0.99929905,0.00004600858,0.00008353942,0.0004108407,0.0000657767,0.00009478095],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005458174,0.00026694802,0.0002505133,0.000065466804,0.00033046163,0.00004297337,0.00022062456,0.000098471304,0.000116678166],"category_scores_gemma":[0.000041303974,0.00027238784,0.00016510404,0.00011581146,0.00003766951,0.000005221481,0.00012747422,0.0001544637,0.0000025758136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024136622,0.00007906304,0.00002916657,0.000014267218,0.00017890998,0.000009534214,0.00022300261,0.0076518888,0.97584975,0.000042280837,0.00007219846,0.013436301],"study_design_scores_gemma":[0.0063975737,0.0028390868,0.018628648,0.000010896304,0.000055819575,0.00017860968,0.00042803946,0.0013101376,0.86746705,0.0000809984,0.10194576,0.0006574095],"about_ca_topic_score_codex":0.000022094255,"about_ca_topic_score_gemma":0.0000022203537,"teacher_disagreement_score":0.1083827,"about_ca_system_score_codex":0.000028056256,"about_ca_system_score_gemma":0.00008349844,"threshold_uncertainty_score":0.9999728},"labels":[],"label_agreement":null},{"id":"W4213120068","doi":"10.1101/2022.02.19.480892","title":"Reproducibility metrics for CRISPR screens","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Context (archaeology); Computer science; Computational biology; Pace; Biology; Data science; Genetics; Gene; Geography","score_opus":0.01792319253131047,"score_gpt":0.2836018699550658,"score_spread":0.26567867742375534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213120068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84482723,0.009743893,0.13784273,0.00027930367,0.0031940318,0.002274053,0.0015119686,0.00028960043,0.000037194914],"genre_scores_gemma":[0.9785954,0.00044155016,0.01877169,0.00020749963,0.0011140051,0.00064125983,0.0000074319305,0.00018165237,0.00003951187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99580973,0.000098738165,0.0005344372,0.0026441172,0.00031855892,0.000594399],"domain_scores_gemma":[0.9947853,0.000041206302,0.00024277096,0.004290539,0.00041390647,0.00022629683],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018937292,0.00052454654,0.00048115998,0.00020636122,0.00020955603,0.00008875952,0.0007332613,0.0004932625,0.000045434244],"category_scores_gemma":[0.0017565266,0.00062963786,0.0003594006,0.00037599387,0.000071960996,0.000004438066,0.0012302102,0.00053094665,0.0000048667785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075713484,0.00014655157,0.0049744565,0.00045232347,0.00023318086,0.000007373926,0.0000039962206,0.001892634,0.987813,0.000116479925,0.004276651,0.00000763986],"study_design_scores_gemma":[0.0004961863,0.00019748996,0.020595005,0.00003361998,0.00014632469,2.0867496e-8,0.0000049216887,0.00044135292,0.83185846,0.000002940382,0.14533578,0.0008879252],"about_ca_topic_score_codex":0.00003939638,"about_ca_topic_score_gemma":0.0000034256886,"teacher_disagreement_score":0.15595457,"about_ca_system_score_codex":0.00012442362,"about_ca_system_score_gemma":0.00040884074,"threshold_uncertainty_score":0.9996155},"labels":[],"label_agreement":null},{"id":"W4213174645","doi":"10.1007/s13311-022-01197-9","title":"CRISPR-Cas9 Gene Therapy for Duchenne Muscular Dystrophy","year":2022,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Duchenne muscular dystrophy; Cas9; Dystrophin; Computational biology; Genetic enhancement; Biology; Guide RNA; Muscular dystrophy; Gene; Genetics; Bioinformatics; Medicine","score_opus":0.063210282270666,"score_gpt":0.387382244489429,"score_spread":0.324171962218763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213174645","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006308234,0.98658967,0.010639257,0.00001932624,0.0007847082,0.0015346295,0.00021906238,0.000042561955,0.000107708474],"genre_scores_gemma":[0.000027036775,0.9951532,0.0012744544,0.0004502774,0.00089171214,0.0008119252,0.00058658567,0.00029647836,0.00050835434],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99799335,0.00012057623,0.0004624134,0.0007519572,0.00020300872,0.00046869804],"domain_scores_gemma":[0.99871564,0.00005548986,0.0001651153,0.0009127323,0.00004781436,0.00010321496],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016645099,0.0005812788,0.000809739,0.00010909039,0.00014992828,0.000049249953,0.0005506465,0.00034685998,0.000105839754],"category_scores_gemma":[0.000027218417,0.0005489221,0.000892351,0.00017121181,0.00004416016,0.0000017677652,0.000092874056,0.00031694,0.0000074372497],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000358277,0.00010043741,8.2822163e-7,0.0016117969,0.00046159243,0.000008906895,0.000018223023,0.00009257326,0.0048953756,0.00002643087,0.00073728955,0.9920107],"study_design_scores_gemma":[0.0005045741,0.00060774863,9.852617e-7,0.000068901776,0.00028286243,0.00006776605,0.0000049461582,0.000021773767,0.0022270093,0.0000107804,0.99566805,0.0005345851],"about_ca_topic_score_codex":0.0000024749681,"about_ca_topic_score_gemma":9.431155e-7,"teacher_disagreement_score":0.9949308,"about_ca_system_score_codex":0.000030658102,"about_ca_system_score_gemma":0.00016931909,"threshold_uncertainty_score":0.99969625},"labels":[],"label_agreement":null},{"id":"W4213285110","doi":"10.1002/9780470015902.a0003069.pub3","title":"<scp>RNA</scp> Editing: Evolutionary Implications","year":2013,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"RNA editing; Biology; RNA; Intron; Genetics; Post-transcriptional modification; Guide RNA; Transfer RNA; Non-coding RNA; RNA silencing; Transcription (linguistics); Nucleotide; Inosine; Computational biology; Gene; Biochemistry; Genome; Genome editing; RNA interference; Adenosine","score_opus":0.00926023228816075,"score_gpt":0.280207451345655,"score_spread":0.27094721905749425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213285110","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028017429,0.012336412,0.0020891372,0.00012077443,0.0008109782,0.00021646955,0.00007184941,0.000039198647,0.98151344],"genre_scores_gemma":[0.01496973,0.01110496,0.011792279,0.00016772789,0.0048560416,0.00010883775,0.00016863634,0.00019299926,0.9566388],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99891746,0.00001996707,0.00022282642,0.0003844561,0.00019979125,0.00025549362],"domain_scores_gemma":[0.9993252,0.000031301923,0.00017313771,0.00030872083,0.00004267746,0.00011896534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011898318,0.00018075011,0.00017749696,0.00013075961,0.00006779769,0.000010925395,0.00045249102,0.00020635591,0.0001640598],"category_scores_gemma":[0.0003512681,0.00016627685,0.00008343802,0.00017952568,0.000280142,0.0000033471426,0.00012726137,0.00007847028,0.000053876083],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[1.5219763e-7,0.00001891139,0.0020302704,0.000029403773,0.000020444966,1.15429536e-7,0.000019666195,0.00007316138,0.0029557298,0.00019896866,0.99410564,0.0005475103],"study_design_scores_gemma":[0.00007189528,0.000070634094,0.0031988118,0.000030998373,0.000012729626,0.0000024116416,0.000107512264,0.00002572722,0.00085966033,0.00006654166,0.99546814,0.00008492861],"about_ca_topic_score_codex":0.00006724812,"about_ca_topic_score_gemma":0.000017837538,"teacher_disagreement_score":0.02487465,"about_ca_system_score_codex":0.0000045329357,"about_ca_system_score_gemma":0.00019456183,"threshold_uncertainty_score":0.6780573},"labels":[],"label_agreement":null},{"id":"W4214692003","doi":"10.3410/f.717971623.793472113","title":"Faculty Opinions recommendation of Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system.","year":2013,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Trans-activating crRNA; Biology; Gene; Genome; CRISPR interference; Bacteriophage; Genetics; Computational biology; DNA; Genome editing; RNA; Escherichia coli","score_opus":0.02025508494387766,"score_gpt":0.3402843956693429,"score_spread":0.3200293107254652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214692003","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000151491795,0.003713464,0.00028125895,0.034992564,0.0018514929,0.001349884,0.9577428,0.00002094418,0.000032438023],"genre_scores_gemma":[0.00024253446,0.001013579,0.00030798564,0.0007143644,0.0006896468,0.0003099172,0.996144,0.000037960002,0.000540012],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99672407,0.00038849554,0.00119618,0.00060319615,0.00073115807,0.00035689076],"domain_scores_gemma":[0.99459887,0.000053145624,0.0011166856,0.0017696554,0.002282654,0.00017901004],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00088614674,0.00054312614,0.000751182,0.00014419814,0.00022825286,0.00015508146,0.001591524,0.00071513955,0.00023368766],"category_scores_gemma":[0.0013741858,0.00031828837,0.0006128507,0.00062052184,0.0002491546,0.00003683047,0.00069931237,0.00058901694,0.00002928243],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017676732,0.000104051425,0.000002623901,0.004783773,0.00019124491,1.4543605e-7,0.000040478153,4.3594184e-7,0.0012188636,0.000028687109,0.99220896,0.001403066],"study_design_scores_gemma":[0.00046711846,0.00011882393,0.0012932793,0.0035243456,0.00015503434,0.00005177146,0.00006001785,0.0000053116714,0.0061651757,0.0000012467599,0.98783827,0.0003196294],"about_ca_topic_score_codex":0.000097634074,"about_ca_topic_score_gemma":0.0000056432605,"teacher_disagreement_score":0.038401194,"about_ca_system_score_codex":0.00006462511,"about_ca_system_score_gemma":0.0002555964,"threshold_uncertainty_score":0.9999269},"labels":[],"label_agreement":null},{"id":"W4214723813","doi":"10.1101/gad.349039.121","title":"Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states","year":2022,"lang":"en","type":"article","venue":"Genes & Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Biofyzikální Ústav, Akademie Věd České Republiky; National Institutes of Health; Canadian Institutes of Health Research; Grantová Agentura České Republiky","keywords":"Biology; Rap1; Telomere; Cell biology; Regulation of gene expression; Gene; Histone; Histone acetyltransferase; Genetics","score_opus":0.004674864617471273,"score_gpt":0.22016213198100948,"score_spread":0.2154872673635382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214723813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878541,0.003133616,0.008530957,0.00006974284,0.00017974446,0.00015896358,0.000013840973,0.000025206913,0.000033832766],"genre_scores_gemma":[0.99705935,0.00035402324,0.0014474364,0.00006581769,0.00010589642,0.0000684241,0.00047126046,0.000023665818,0.0004041379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990727,0.000028966047,0.0001995446,0.00031793508,0.00015031878,0.00023056494],"domain_scores_gemma":[0.99972886,0.0000039076826,0.000037934118,0.0001359909,0.000024370385,0.00006895627],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013536093,0.00015251983,0.000109839915,0.000056530218,0.0002741144,0.000019634115,0.00007246686,0.0000371363,0.00003054841],"category_scores_gemma":[0.000001026856,0.00016713561,0.00003589256,0.00006646313,0.00001644063,0.0000030139918,0.00013586346,0.00006524177,0.0000031659174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007959729,0.000029232806,0.0021441728,0.00006219038,0.00009675968,0.000004397607,0.0008004749,0.024250237,0.95252657,0.0000015593884,0.0001879641,0.019816844],"study_design_scores_gemma":[0.000953135,0.0001341258,0.041245498,0.000007609504,0.000036629608,0.000021355458,0.00046393473,0.00018265228,0.9023803,0.000032497017,0.05420346,0.0003388275],"about_ca_topic_score_codex":0.000009371449,"about_ca_topic_score_gemma":0.000008053993,"teacher_disagreement_score":0.0540155,"about_ca_system_score_codex":0.000032639444,"about_ca_system_score_gemma":0.000038230075,"threshold_uncertainty_score":0.68155926},"labels":[],"label_agreement":null},{"id":"W4214840711","doi":"10.1089/crispr.2021.0109","title":"Increasing the Targeting Scope of CRISPR Base Editing System Beyond NGG","year":2022,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Cas9; Scope (computer science); Computational biology; Biology; Point mutation; DNA; Workflow; Computer science; Base pair; Genetics; Mutation; Gene; Programming language; Database","score_opus":0.02184174884512836,"score_gpt":0.3347463353584101,"score_spread":0.31290458651328174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214840711","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025127042,0.9924777,0.0039250595,0.000060826653,0.0014767292,0.00038652102,0.000046246867,0.000015234825,0.0013604168],"genre_scores_gemma":[0.0028440014,0.9926433,0.00058390765,0.000054173157,0.0035706141,0.000038525424,0.000067606445,0.00010954315,0.000088308196],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967299,0.00096183043,0.0010345775,0.00033709954,0.0004475696,0.00048903114],"domain_scores_gemma":[0.9979648,0.00026348035,0.0008719121,0.00066630496,0.000110678346,0.00012284699],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00383715,0.00044348056,0.0008435428,0.00010533955,0.0008305705,0.000119799006,0.0011277273,0.00019443208,0.00013590563],"category_scores_gemma":[0.00056803715,0.00025947994,0.0007287339,0.0002506249,0.0001073971,0.0000055060436,0.00056133745,0.0012047454,0.0000059121458],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010050277,0.00011856689,0.000026434052,0.02137949,0.0020192673,0.00017178972,0.0007232739,0.0018988963,0.01029522,0.00026297034,0.059908077,0.90309554],"study_design_scores_gemma":[0.00016513397,0.000086385626,0.0000018325289,0.002258559,0.0007412763,0.0028689345,0.0012239956,0.000049668386,0.0014859516,0.0000070530436,0.99081093,0.0003002772],"about_ca_topic_score_codex":0.000027161068,"about_ca_topic_score_gemma":0.0000025343234,"teacher_disagreement_score":0.93090284,"about_ca_system_score_codex":0.000087088396,"about_ca_system_score_gemma":0.00030683863,"threshold_uncertainty_score":0.99998575},"labels":[],"label_agreement":null},{"id":"W4220675702","doi":"10.21203/rs.3.rs-738081/v1","title":"RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells.","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"Samsung Biomedical Research Institute; Institut National Du Cancer; Ligue Contre le Cancer; University of Toronto; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; European Commission","keywords":"Embryonic stem cell; Ribosome biogenesis; Cell biology; Stem cell; Biogenesis; Ribosome; Translation (biology); State (computer science); Chemistry; Biology; Computer science; RNA; Biochemistry; Messenger RNA; Gene","score_opus":0.03619816737617818,"score_gpt":0.35608554320964064,"score_spread":0.31988737583346244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220675702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829997,0.013796831,0.00077864464,0.0003120381,0.0001766377,0.0013618619,0.00033641665,0.000029887988,0.0002079723],"genre_scores_gemma":[0.99250335,0.0039981925,0.00032934008,0.000008742375,0.00018507706,0.00047011845,0.00072123663,0.00007095942,0.0017129964],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99710137,0.0003131968,0.0003269655,0.000875562,0.00064884557,0.00073403696],"domain_scores_gemma":[0.9989561,0.000040144416,0.00005112924,0.00057808775,0.00018764066,0.00018688833],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009783509,0.0002973307,0.0002800708,0.0003722757,0.0001575167,0.000100692094,0.00040613217,0.00028797745,0.000040055107],"category_scores_gemma":[0.000019971823,0.0003235776,0.00014848253,0.00033821948,0.00012932948,0.000003711706,0.0010045156,0.00083894434,0.0000029992748],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015145182,0.0024608166,0.10286299,0.016091678,0.0010301649,0.0007764313,0.00840488,0.20152548,0.43615687,0.00058502186,0.0025368219,0.22605433],"study_design_scores_gemma":[0.015924111,0.009567945,0.14894763,0.0029176306,0.00025879013,0.0001683487,0.028148038,0.037421335,0.3038232,0.004704444,0.4384128,0.009705725],"about_ca_topic_score_codex":0.00019923755,"about_ca_topic_score_gemma":0.00034556503,"teacher_disagreement_score":0.43587598,"about_ca_system_score_codex":0.00009333044,"about_ca_system_score_gemma":0.0004714121,"threshold_uncertainty_score":0.9999216},"labels":[],"label_agreement":null},{"id":"W4220704556","doi":"10.1016/j.omtn.2022.03.022","title":"CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer’s disease PSEN1 M146L mutation","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Institutes of Health; Åhlén-stiftelsen; Vetenskapsrådet; Alzheimerfonden; Massachusetts General Hospital; Gun och Bertil Stohnes Stiftelse; Hjärnfonden; National Institute on Aging; Deutsche Forschungsgemeinschaft; Stiftelsen för Gamla Tjänarinnor","keywords":"CRISPR; PSEN1; Disease; Mutation; Amyloid (mycology); Medicine; Dementia; Cancer research; Alzheimer's disease; Biology; Amyloid precursor protein; Genetics; Pathology; Gene","score_opus":0.01164431016907894,"score_gpt":0.2858149682671727,"score_spread":0.2741706580980937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220704556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902547,0.0047068326,0.0034865378,0.00073302636,0.00007104677,0.0005352635,0.00002311214,0.000032456774,0.00015700441],"genre_scores_gemma":[0.99834925,0.00012774054,0.00022108141,0.0005112318,0.00008344998,0.00030968417,0.00017576123,0.00007272198,0.00014909923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850994,0.0001761289,0.00021242772,0.0004707255,0.00028194845,0.00034884212],"domain_scores_gemma":[0.9991637,0.000010260099,0.0000693041,0.0006108026,0.00003238589,0.0001135413],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014336144,0.00028354497,0.00017116562,0.00007015369,0.00027618377,0.000044795346,0.00029065815,0.00005791457,0.00007426569],"category_scores_gemma":[0.0000067289347,0.00021947363,0.00012953766,0.00017937568,0.00008532174,0.000005317562,0.00009864496,0.00013430775,0.0000040176965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010161897,0.0003068652,0.0023495434,0.000007988003,0.00029365477,0.0002550343,0.0007640088,0.0747701,0.9129558,0.00012489584,0.00068160245,0.006474294],"study_design_scores_gemma":[0.0056582955,0.0047336384,0.047131576,0.00002607006,0.0001719092,0.00007739767,0.0007751604,0.0013653764,0.84134585,0.00025067895,0.09737329,0.0010907378],"about_ca_topic_score_codex":0.000079165875,"about_ca_topic_score_gemma":0.00010318254,"teacher_disagreement_score":0.09669169,"about_ca_system_score_codex":0.00005551411,"about_ca_system_score_gemma":0.000081185004,"threshold_uncertainty_score":0.89498746},"labels":[],"label_agreement":null},{"id":"W4220722511","doi":"10.1039/d2cc00792d","title":"Dual-amplified CRISPR-Cas12a bioassay for HIV-related nucleic acids","year":2022,"lang":"en","type":"article","venue":"Chemical Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Fundamental Research Fund of Shandong University; Sichuan University; Department of Science and Technology of Sichuan Province; National Natural Science Foundation of China","keywords":"Nucleic acid; CRISPR; Bioassay; DNA; Nucleic Acid Amplification Tests; Human immunodeficiency virus (HIV); Computational biology; Chemistry; Combinatorial chemistry; Biology; Molecular biology; Nanotechnology; Chromatography; Biochemistry; Genetics; Gene; Materials science; Virology","score_opus":0.01940045019359637,"score_gpt":0.317894992915263,"score_spread":0.29849454272166664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220722511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9070079,0.010994425,0.049290948,0.013248634,0.0005830466,0.0017087323,0.000961356,0.00032184582,0.015883114],"genre_scores_gemma":[0.9893992,0.00010873062,0.0074293325,0.00022384067,0.000052749365,0.00034425224,0.0015914487,0.000035026867,0.00081542967],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991882,0.000043619657,0.00022991846,0.00023626843,0.00008776898,0.00021426838],"domain_scores_gemma":[0.9984783,0.000058443777,0.000048651436,0.0012807646,0.00005645596,0.00007736651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016004004,0.00012240643,0.00011728574,0.00003445934,0.0003063423,0.000016458951,0.0006597431,0.00008816126,0.00006098306],"category_scores_gemma":[0.00010881213,0.00014214267,0.00012446252,0.00014306286,0.000097478085,0.000002046931,0.00083688303,0.00021145237,0.000011131351],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002001807,0.00010665075,0.00010072417,0.000009642643,0.00004697363,2.1336427e-7,0.00008817801,0.00017418845,0.98534983,0.0012132531,0.012036267,0.00085405784],"study_design_scores_gemma":[0.00067933736,0.00007083158,0.000112138834,0.0000038233393,0.000037082293,0.000021317863,0.00022262399,0.0015982303,0.42288566,0.00049040775,0.5736243,0.00025421358],"about_ca_topic_score_codex":0.000003980622,"about_ca_topic_score_gemma":0.000002062758,"teacher_disagreement_score":0.5624642,"about_ca_system_score_codex":0.000029983223,"about_ca_system_score_gemma":0.000037991133,"threshold_uncertainty_score":0.579641},"labels":[],"label_agreement":null},{"id":"W4220731393","doi":"10.1007/978-1-0716-2181-3_11","title":"Approaches for CRISPR/Cas9 Genome Editing in C. elegans","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Palindrome; Cas9; Genome editing; Biology; Genetics; Genome; Computational biology; Nuclease; Gene","score_opus":0.032213428758166775,"score_gpt":0.41556173343698977,"score_spread":0.38334830467882297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220731393","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06986596,0.0025079197,0.9263059,0.00016989924,0.00030427243,0.0003885109,0.000030288165,0.0000115105,0.00041572697],"genre_scores_gemma":[0.34900975,0.000032562068,0.6492946,0.00035113716,0.00018933843,0.00069833046,0.00025278554,0.00005168392,0.00011979194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981289,0.00051667757,0.0003188626,0.0005300494,0.00005689538,0.00044864643],"domain_scores_gemma":[0.9995001,0.00005499349,0.0000581065,0.00032486534,0.000017669896,0.000044257973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014794116,0.00018007745,0.00025001768,0.0001788012,0.000066016604,0.00000790643,0.00030475634,0.00014788199,0.000020076945],"category_scores_gemma":[0.000276559,0.00020737661,0.00011486264,0.00022200824,0.000049515853,0.0000013552852,0.00030235914,0.00023157851,4.4451753e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003831712,0.000053390733,0.0012340513,0.000021772626,0.000022157932,0.000008759147,0.000097688906,0.015971266,0.9732867,0.0009862634,0.0000283315,0.008251327],"study_design_scores_gemma":[0.0018068249,0.000800534,0.0012918838,0.0000065458426,0.000022964925,0.00006760411,0.00090530503,0.006575768,0.85250527,0.004183332,0.13115658,0.000677366],"about_ca_topic_score_codex":0.000022127015,"about_ca_topic_score_gemma":0.000026407053,"teacher_disagreement_score":0.2791438,"about_ca_system_score_codex":0.000041896317,"about_ca_system_score_gemma":0.000041429717,"threshold_uncertainty_score":0.8456573},"labels":[],"label_agreement":null},{"id":"W4220738790","doi":"10.1139/bcb-2021-0504","title":"Establishing an incentive-based multistakeholder approach to dual-use DNA screening","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biosecurity; Incentive; Mandate; Risk analysis (engineering); Business; Variety (cybernetics); Biotechnology; Political science; Medicine; Law; Biology; Computer science; Economics","score_opus":0.01990738222087023,"score_gpt":0.27452074702164164,"score_spread":0.2546133648007714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220738790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9521509,0.00066493714,0.045879066,0.0000337927,0.00010737104,0.00016179732,0.00013553452,0.00002961372,0.00083702424],"genre_scores_gemma":[0.9905422,0.000011652952,0.0071130246,0.00038072115,0.00017307646,0.00007135564,0.0010886347,0.000026349091,0.0005930294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986822,0.000073573196,0.00017847265,0.00063958357,0.00008412502,0.00034201535],"domain_scores_gemma":[0.99932915,0.00002612643,0.00005115632,0.00036861407,0.00003553228,0.00018944521],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020237158,0.00020579073,0.00015071008,0.000043121217,0.00024662845,0.0000497336,0.00019871068,0.00014288636,0.000024819597],"category_scores_gemma":[0.00006326559,0.00022708639,0.00005576048,0.000115528936,0.000065030144,0.000005473076,0.00030077717,0.00016671086,6.79013e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008501765,0.00012626823,0.0013630405,0.000030550018,0.000014695388,0.0000030386386,0.00005742382,0.0033647078,0.9924642,0.000014662506,0.00034979125,0.0021265927],"study_design_scores_gemma":[0.0006429762,0.00025696386,0.0004405985,0.0000037357286,0.000015061842,0.0000134350485,0.00047042946,0.0020236988,0.93649524,0.0000030097588,0.0592639,0.00037095565],"about_ca_topic_score_codex":0.000035909783,"about_ca_topic_score_gemma":0.0000021289795,"teacher_disagreement_score":0.058914106,"about_ca_system_score_codex":0.000015704492,"about_ca_system_score_gemma":0.000043130633,"threshold_uncertainty_score":0.9260314},"labels":[],"label_agreement":null},{"id":"W4220818367","doi":"10.1371/journal.pone.0265635","title":"Climate solution or corporate co-optation? US and Canadian publics’ views on agricultural gene editing","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"Genome British Columbia","keywords":"Agriculture; Climate change; Naturalness; Perception; Public relations; Political science; Psychology; Biology; Ecology","score_opus":0.04404148743510049,"score_gpt":0.26217204702783087,"score_spread":0.21813055959273037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220818367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982513,0.0002639197,0.00006320591,0.0003034909,0.00007958767,0.00017128441,0.00013399986,0.000012999854,0.00072019605],"genre_scores_gemma":[0.9973987,0.00014400874,0.00080104964,0.00028277363,0.00026609987,0.00005717236,0.00068581477,0.000012848387,0.0003515317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993131,0.000027997905,0.000118307034,0.00019489128,0.00011895941,0.00022675323],"domain_scores_gemma":[0.99967176,0.000004961723,0.00005823343,0.00010983618,0.00003914973,0.000116051146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001234473,0.00009060625,0.00008891628,0.00004347062,0.00024000432,0.000029833798,0.00006574423,0.00003861539,0.00005691157],"category_scores_gemma":[0.000033583143,0.00008256627,0.000020202895,0.00007332838,0.000014137275,0.0000031144525,0.00004922986,0.00008528007,0.0000056341587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030848227,0.00010357866,0.0034355754,0.000034688204,0.000059552644,0.000006653353,0.000091955386,0.000637466,0.99306935,0.00003824786,0.001776166,0.00071591605],"study_design_scores_gemma":[0.0012275492,0.0011835912,0.082017355,0.000043967262,0.00011422069,0.00006227641,0.00057515805,0.003448895,0.8920301,0.000021171172,0.01860649,0.0006692287],"about_ca_topic_score_codex":0.00045706893,"about_ca_topic_score_gemma":0.004935178,"teacher_disagreement_score":0.10103925,"about_ca_system_score_codex":0.000035705776,"about_ca_system_score_gemma":0.00004280225,"threshold_uncertainty_score":0.33669546},"labels":[],"label_agreement":null},{"id":"W4220833543","doi":"10.1016/j.celrep.2022.110517","title":"Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research; National Eye Institute; Intellectual and Developmental Disabilities Research Center; National Institutes of Health; Regione Toscana; Ministero dell’Istruzione, dell’Università e della Ricerca; National Human Genome Research Institute; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Broad Institute; Robert and Janice McNair Foundation; ZonMw; Simons Foundation Autism Research Initiative; Office of Research Infrastructure Programs, National Institutes of Health; Dipartimenti di Eccellenza; American Academy of Neurology; Warren Alpert Foundation","keywords":"Phenotype; Autism spectrum disorder; Autism; Genetics; Biology; Missense mutation; Gene; Neurodevelopmental disorder; Candidate gene; Neuroscience; Medicine; Psychiatry","score_opus":0.006846149360507695,"score_gpt":0.22723344814035348,"score_spread":0.22038729877984578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220833543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99524474,0.0007136648,0.0035745788,0.000017248434,0.00014196812,0.00007678599,0.000060956012,0.0000037659279,0.00016627922],"genre_scores_gemma":[0.99905765,0.000035101722,0.0005405371,0.000020501777,0.000012207658,0.000008910599,0.00012646029,0.000010736514,0.00018792252],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992278,0.000025963016,0.00024466298,0.00023910041,0.00012738004,0.00013508048],"domain_scores_gemma":[0.99969697,0.000014807857,0.00009008953,0.00014710428,0.0000118607695,0.000039171737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012824211,0.00008977943,0.000118231976,0.000056588124,0.000045362445,0.000007106585,0.000045334735,0.00002533518,0.00001623124],"category_scores_gemma":[0.000042149655,0.000103123515,0.000038254813,0.00007780398,0.000035536603,0.0000072824787,0.0001886758,0.000060757313,3.30627e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049807662,0.0000654344,0.26577073,0.00006618865,0.000020822079,0.0002119597,0.00013874445,0.021670576,0.7116286,0.000008560935,0.00006743226,0.00030109345],"study_design_scores_gemma":[0.0004907003,0.0000887212,0.90293896,0.00002379793,0.000020091895,0.00035801533,0.00038373715,0.00039051333,0.09458658,0.00013637987,0.00040830375,0.0001742125],"about_ca_topic_score_codex":0.00003563517,"about_ca_topic_score_gemma":0.0000027656201,"teacher_disagreement_score":0.6371682,"about_ca_system_score_codex":0.000013596901,"about_ca_system_score_gemma":0.0000988482,"threshold_uncertainty_score":0.4205255},"labels":[],"label_agreement":null},{"id":"W4220928625","doi":"10.1038/s41587-022-01254-w","title":"An engineered prime editor with enhanced editing efficiency in plants","year":2022,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":240,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Genome editing; Prime (order theory); Computational biology; Computer science; Nucleic acid; Murine leukemia virus; Reverse transcriptase; Cell culture; Chemistry; Biology; Combinatorial chemistry; RNA; Biochemistry; Genetics; Genome; Mathematics; Gene","score_opus":0.0016194211725248002,"score_gpt":0.241036724706882,"score_spread":0.2394173035343572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220928625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98408604,0.0013134932,0.012442073,0.0002430973,0.0014925111,0.00018639927,0.000028658773,0.00009063174,0.000117111675],"genre_scores_gemma":[0.99739736,0.000026611155,0.0013235784,0.000080021986,0.00096148194,0.000045814428,0.00010075633,0.000023847024,0.000040544008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990171,0.000021930051,0.00012708698,0.00039647263,0.00013550247,0.00030188414],"domain_scores_gemma":[0.99953187,0.0000067100827,0.000038660204,0.00036754293,0.000017641654,0.000037569876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012435149,0.00014257552,0.00012833413,0.00015847909,0.000070765214,0.0000063427856,0.00032684792,0.00049680535,0.000016639868],"category_scores_gemma":[0.000042816006,0.0001395878,0.00002365449,0.00022297379,0.000040650622,0.0000022505797,0.00012420568,0.00072367175,0.000001194353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053062075,0.00006756311,0.00012293762,0.000005479662,0.000010411305,0.00001385091,0.000033922843,0.003799916,0.9931153,0.00005972706,0.00045784513,0.0022599793],"study_design_scores_gemma":[0.00053770654,0.0007008881,0.00041175145,0.0000057182506,0.0000035181856,0.00005405223,0.0002101628,0.00058117777,0.96826285,0.000009362359,0.029027814,0.0001949847],"about_ca_topic_score_codex":0.000004971292,"about_ca_topic_score_gemma":0.000028115917,"teacher_disagreement_score":0.02856997,"about_ca_system_score_codex":0.000025255431,"about_ca_system_score_gemma":0.000042081392,"threshold_uncertainty_score":0.56922257},"labels":[],"label_agreement":null},{"id":"W4220950323","doi":"10.21203/rs.3.rs-1353802/v1","title":"Efficient in vitro and in vivo self-repression of SpCas9 gene using a molecular Hara-Kiri method.","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Cas9; Gene; Biology; Genome editing; CRISPR; Molecular biology; Genetics","score_opus":0.0288627358899485,"score_gpt":0.4339232737333048,"score_spread":0.4050605378433563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220950323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800776,0.007966922,0.010948613,0.000029492468,0.000073382136,0.00066774496,0.00007916418,0.000008225546,0.00014882551],"genre_scores_gemma":[0.97839177,0.00043363735,0.020894911,0.000007495656,0.000046808975,0.00009498767,0.00006248608,0.000041757274,0.000026150545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99744487,0.0005204008,0.00035507898,0.0007226912,0.00050428545,0.0004526575],"domain_scores_gemma":[0.9990402,0.000050063398,0.00006655601,0.00063140516,0.00011169582,0.000100089615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016986704,0.00021208769,0.0003319062,0.00046174866,0.000048780395,0.000024426196,0.00029103682,0.00028269747,0.000032352604],"category_scores_gemma":[0.00018483929,0.00023065794,0.000100961945,0.0003133586,0.000049496564,9.671054e-7,0.0021328607,0.00074073876,2.6260264e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012275025,0.00009836077,0.00044823604,0.00045455748,0.000025539328,0.000050500425,0.00018175662,0.26030952,0.7378677,0.0000029990517,0.000009563546,0.00042851164],"study_design_scores_gemma":[0.00046836585,0.000080223974,0.0008370232,0.00018230746,0.00001093879,0.00001119078,0.00020279756,0.08803596,0.909505,0.000034455636,0.00042134567,0.00021035633],"about_ca_topic_score_codex":0.00029174058,"about_ca_topic_score_gemma":0.00001754598,"teacher_disagreement_score":0.17227356,"about_ca_system_score_codex":0.00011081002,"about_ca_system_score_gemma":0.00022076575,"threshold_uncertainty_score":0.9405958},"labels":[],"label_agreement":null},{"id":"W4220962256","doi":"10.1038/s42003-022-03149-7","title":"Engineered Campylobacter jejuni Cas9 variant with enhanced activity and broader targeting range","year":2022,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development","keywords":"Cas9; Genome editing; CRISPR; Biology; Campylobacter jejuni; Genome engineering; Endonuclease; Genome; Guide RNA; Computational biology; DNA; Gene; Genetics","score_opus":0.010194855432485075,"score_gpt":0.30000772230807166,"score_spread":0.2898128668755866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220962256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9654111,0.0036733595,0.02889354,0.0006493856,0.000083623694,0.00021520344,0.000055520522,0.00002994945,0.0009882986],"genre_scores_gemma":[0.99429566,0.00043024242,0.004673521,0.00010015145,0.00003762382,0.000078465324,0.00023104098,0.000016581962,0.00013671622],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993432,0.00013049484,0.00010467978,0.0002117906,0.000034308043,0.00017548267],"domain_scores_gemma":[0.99909586,0.0000354965,0.000042285486,0.0007465716,0.00003511371,0.000044649347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014201332,0.00011063433,0.000113663584,0.000040223294,0.00025132598,0.00000912006,0.0003311835,0.00006144563,0.00004141031],"category_scores_gemma":[0.00003227863,0.00010540197,0.000026545358,0.000094133524,0.00010129849,0.0000024495166,0.00057151634,0.00017684152,0.0000012955338],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054739565,0.00008264596,0.000937113,0.00000841459,0.00007151442,0.000001017463,0.00022413043,0.00052490924,0.9937374,0.00036608396,0.00021169416,0.0037803268],"study_design_scores_gemma":[0.0045428537,0.002433086,0.025094874,0.000024272047,0.0001724131,0.0004964388,0.0016656278,0.0081148585,0.39145026,0.0002804289,0.5639146,0.0018103269],"about_ca_topic_score_codex":0.000046152367,"about_ca_topic_score_gemma":0.00005252962,"teacher_disagreement_score":0.6022872,"about_ca_system_score_codex":0.000015035274,"about_ca_system_score_gemma":0.000031944837,"threshold_uncertainty_score":0.42981672},"labels":[],"label_agreement":null},{"id":"W4220966726","doi":"10.1159/000522227","title":"Genetic Testing and FOX News","year":2022,"lang":"en","type":"article","venue":"American Journal of Nephrology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Medicine; Genetic testing; Genetics; Evolutionary biology; Internal medicine; Biology","score_opus":0.006756826363837415,"score_gpt":0.26298277671899994,"score_spread":0.25622595035516255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220966726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99368465,0.0016396664,0.004128828,0.00031028365,0.000100760786,0.000031243027,0.0000020287343,0.0000026774896,0.000099847784],"genre_scores_gemma":[0.9894732,0.00010609823,0.008839131,0.001353266,0.00018772634,0.000003270154,7.9185907e-7,0.0000128373495,0.000023666238],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993922,0.000069480164,0.00019239649,0.000114011076,0.000077630335,0.00015426001],"domain_scores_gemma":[0.99960613,0.000032562377,0.00015642357,0.00010643248,0.00004226206,0.000056201137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011572768,0.00007529863,0.00014895004,0.000058928228,0.0000658436,0.0000054536813,0.00012794133,0.00001626197,0.000018885938],"category_scores_gemma":[0.00005744553,0.00007567065,0.0000414647,0.000104370345,0.00010227028,0.0000011419063,0.00012635962,0.00013184518,4.2355893e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014968443,0.000036511705,0.031934205,0.0000041190615,0.00009397427,0.00006075228,0.00012378047,0.0075677773,0.74465364,0.000007879004,0.0017495594,0.21361813],"study_design_scores_gemma":[0.002205638,0.02038086,0.33529314,0.0000079598385,0.0001560245,0.018448941,0.0020724414,0.0011076706,0.009564212,0.00044292526,0.6096714,0.00064875215],"about_ca_topic_score_codex":0.000031597203,"about_ca_topic_score_gemma":0.0000048053585,"teacher_disagreement_score":0.7350894,"about_ca_system_score_codex":0.000007451877,"about_ca_system_score_gemma":0.00004608843,"threshold_uncertainty_score":0.30857596},"labels":[],"label_agreement":null},{"id":"W4220976184","doi":"10.1089/crispr.2021.0094","title":"Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing","year":2022,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute for Health and Care Research","keywords":"Epigenetics; Genome editing; CRISPR; Equity (law); Bench to bedside; Context (archaeology); Engineering ethics; Computer science; Data science; Computational biology; Political science; Biology; Medicine; Genetics; Engineering; Gene","score_opus":0.024939329458564634,"score_gpt":0.37673423256247923,"score_spread":0.3517949031039146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220976184","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000006675493,0.9962156,0.0006847509,0.0005644201,0.0018258585,0.0003589839,0.00003089012,0.0000035041728,0.00030932226],"genre_scores_gemma":[0.000041655345,0.988889,0.0001637768,0.00012330458,0.010531183,0.000053788615,0.000074124626,0.000045406505,0.00007780561],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977387,0.000476882,0.00089330575,0.00021623218,0.00038810863,0.00028672832],"domain_scores_gemma":[0.99883926,0.00016703634,0.00050176546,0.00038208673,0.00006029992,0.00004953881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020644264,0.00027505428,0.00066734705,0.000071810726,0.00021063049,0.00002878978,0.0007252645,0.000115318406,0.0003455791],"category_scores_gemma":[0.0003698635,0.00016379617,0.00053354684,0.0002191366,0.0000716827,0.0000029647833,0.00014092737,0.0008580622,0.0000031134089],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007969078,0.000051518047,0.0000107043725,0.03015545,0.00033381407,0.00001470696,0.00033928946,0.00032505853,0.00013648291,0.000043785516,0.074368514,0.8942127],"study_design_scores_gemma":[0.00008808667,0.00004607962,0.000005479767,0.012981991,0.00026378082,0.00032659242,0.00008692725,0.000009313503,0.0000568558,0.000029936928,0.98594207,0.00016287735],"about_ca_topic_score_codex":0.0000064935202,"about_ca_topic_score_gemma":0.000006947498,"teacher_disagreement_score":0.9115736,"about_ca_system_score_codex":0.00002641617,"about_ca_system_score_gemma":0.00025009547,"threshold_uncertainty_score":0.6679414},"labels":[],"label_agreement":null},{"id":"W4221008288","doi":"10.5206/uwomj.v90i1.14009","title":"CRISPR: On the road to restoring sight to the blind","year":2022,"lang":"en","type":"article","venue":"University of Western Ontario Medical Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Disease; Blindness; Cas9; Medicine; Biology; Gene; Genetics; Pathology; Optometry","score_opus":0.012896188592169445,"score_gpt":0.2568037429495783,"score_spread":0.24390755435740885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221008288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9811986,0.0000593768,0.007618068,0.010001511,0.0003307742,0.00009460678,0.0000032727642,0.0000027550639,0.00069102034],"genre_scores_gemma":[0.9954647,0.000019332881,0.00013115874,0.0013084866,0.00022224316,4.0686257e-7,0.0000022453717,0.000006161791,0.0028452834],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99911875,0.00006389455,0.00009421665,0.00012337732,0.00044804096,0.00015173916],"domain_scores_gemma":[0.9995067,0.00001982292,0.00003533502,0.00020739058,0.00003276737,0.00019799093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045202006,0.000069263275,0.00007756835,0.00004090407,0.00034085894,0.000012335528,0.00058929116,0.0000359857,0.00051007216],"category_scores_gemma":[0.00005978878,0.00004991401,0.000070944654,0.00006561694,0.000026095493,0.0000016511843,0.0003591767,0.00037982178,0.000009294215],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00745852,0.0012559808,0.11600811,0.00004697607,0.0014954662,0.0017687829,0.094914354,0.13806374,0.13692799,0.00039585694,0.34730202,0.15436219],"study_design_scores_gemma":[0.00047516992,0.000585361,0.020550845,0.000021726324,0.00001927729,0.00012893976,0.0018395461,0.000021305837,0.0023501948,0.0000047271437,0.9739028,0.000100093814],"about_ca_topic_score_codex":0.001689244,"about_ca_topic_score_gemma":0.021066725,"teacher_disagreement_score":0.6266008,"about_ca_system_score_codex":0.00008114409,"about_ca_system_score_gemma":0.0001778382,"threshold_uncertainty_score":0.99679625},"labels":[],"label_agreement":null},{"id":"W4221010294","doi":"10.3389/fgeed.2022.863193","title":"Contributions of Genome Editing Technologies Towards Improved Nutrition, Environmental Sustainability and Poverty Reduction","year":2022,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Sustainability; Food security; Poverty; Agriculture; Sustainable development; Natural resource economics; Sustainable agriculture; Genome editing; Production (economics); Agricultural productivity; Emerging technologies; Business; Biotechnology; Economic growth; Environmental planning; Agricultural economics; Environmental economics; Economics; Geography; Biology; CRISPR; Computer science; Ecology","score_opus":0.00563715556774878,"score_gpt":0.2685998629464147,"score_spread":0.2629627073786659,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221010294","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00047169573,0.9887882,0.007889691,0.00004040002,0.0011072764,0.00092684955,0.00070729275,0.000033860448,0.000034744346],"genre_scores_gemma":[0.0063452115,0.98826855,0.0022914133,0.0000034962477,0.0009868656,0.00035022196,0.0016703053,0.00004449741,0.000039417962],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99817073,0.00008730576,0.0006280883,0.00058022153,0.00013998653,0.00039366033],"domain_scores_gemma":[0.99922884,0.000015142907,0.00031478915,0.00035668354,0.00003677213,0.000047785972],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044868307,0.0003212457,0.0007489641,0.00023470937,0.00014965494,0.000018949631,0.0002493688,0.00037673634,0.000013679942],"category_scores_gemma":[0.00038233952,0.00035369713,0.00020905198,0.0002046056,0.00017379617,0.00000844818,0.0004163248,0.0004290117,1.4166318e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024429692,0.00022809423,0.000114595765,0.012262825,0.00033789445,0.000010666487,0.0001922264,0.00018867046,0.010946964,0.000011237859,0.0009152968,0.9747671],"study_design_scores_gemma":[0.000349455,0.0001439313,0.000038745282,0.0002418664,0.00015268191,0.00005237909,0.004721749,0.00005752326,0.00076256535,0.00011511769,0.9929891,0.00037484153],"about_ca_topic_score_codex":0.000012296575,"about_ca_topic_score_gemma":8.780286e-7,"teacher_disagreement_score":0.99207383,"about_ca_system_score_codex":0.00044596894,"about_ca_system_score_gemma":0.00013566864,"threshold_uncertainty_score":0.9998915},"labels":[],"label_agreement":null},{"id":"W4221037108","doi":"10.1038/s41467-022-29202-x","title":"Guide RNAs containing universal bases enable Cas9/Cas12a recognition of polymorphic sequences","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Alberta","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Seoul National University; Government of Canada","keywords":"CRISPR; Computational biology; Cas9; Biology; Guide RNA; Genetics; Gene; Genome editing","score_opus":0.019727812259224976,"score_gpt":0.31587363409982255,"score_spread":0.29614582184059757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221037108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8276635,0.10562124,0.004460319,0.0046549193,0.0008536512,0.0007696933,0.0008901845,0.00012017877,0.054966312],"genre_scores_gemma":[0.99420714,0.000868871,0.003660433,0.0001879663,0.0000383042,0.000025398525,0.000563019,0.000011014029,0.0004378646],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99943507,0.0000904059,0.00014635976,0.00012633404,0.00009443675,0.0001074237],"domain_scores_gemma":[0.99910635,0.00004652811,0.00007006851,0.00065737544,0.00008911011,0.000030589777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016948894,0.00007267328,0.000081579565,0.000056819263,0.00022563156,0.0000069220746,0.0004710752,0.00008286848,0.00005599488],"category_scores_gemma":[0.0000961315,0.00008356952,0.000054090004,0.00014826769,0.00006226557,0.0000035986252,0.0003690508,0.00028851908,0.00000117731],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060496575,0.00013189622,0.0017719987,0.00001849388,0.00011575194,0.000004409738,0.00027290403,0.0021388275,0.9751536,0.0014586314,0.009076858,0.009796093],"study_design_scores_gemma":[0.00045602449,0.00030360965,0.00059820234,0.000018877392,0.000051440344,0.000066292734,0.0018215495,0.00067084015,0.24802305,0.0001443895,0.74760455,0.00024117508],"about_ca_topic_score_codex":0.00017641722,"about_ca_topic_score_gemma":0.00026803405,"teacher_disagreement_score":0.7385277,"about_ca_system_score_codex":0.000025365145,"about_ca_system_score_gemma":0.00009207792,"threshold_uncertainty_score":0.3407866},"labels":[],"label_agreement":null},{"id":"W4221054634","doi":"10.5281/zenodo.6259304","title":"Review of The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity","year":2022,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Plasmid; CRISPR; DNA; Biology; Computational biology; Genetics; Gene","score_opus":0.013268388641168657,"score_gpt":0.2631058860270009,"score_spread":0.24983749738583225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221054634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98996323,0.0039118063,0.0016475182,0.000646392,0.00012055059,0.00045668433,0.00018593491,0.00004755976,0.0030203303],"genre_scores_gemma":[0.99707144,0.0021653287,0.00011846783,0.00013324287,0.000030720938,9.3424966e-8,0.00016988594,0.00020453308,0.00010628456],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992,0.00014006523,0.00013614752,0.00021965888,0.00015365287,0.00015046402],"domain_scores_gemma":[0.99954677,0.000004774978,0.000054808683,0.00027919613,0.00007139289,0.000043048884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044972793,0.00007880739,0.00009927787,0.000046889134,0.00042956226,0.000028393264,0.00035902605,0.000027232,0.0005497733],"category_scores_gemma":[0.00023883623,0.00007273427,0.000038779082,0.00023230094,0.00005947994,0.0000063005823,0.0013403869,0.00014654509,0.0000096500935],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004770814,0.00014123994,0.00008245374,0.000570831,0.000020328109,0.0000014685505,0.00019443574,0.00044352017,0.9562229,0.00008602268,0.035550468,0.0066386536],"study_design_scores_gemma":[0.00039334106,0.00023127024,0.0061340113,0.00014522286,0.0000087101125,0.00007126852,0.00013436355,0.0002575261,0.10174607,0.000007863011,0.89074004,0.00013033653],"about_ca_topic_score_codex":0.000010441407,"about_ca_topic_score_gemma":3.050887e-7,"teacher_disagreement_score":0.85518956,"about_ca_system_score_codex":0.000028228103,"about_ca_system_score_gemma":0.0000046576833,"threshold_uncertainty_score":0.60196316},"labels":[],"label_agreement":null},{"id":"W4221072882","doi":"10.1016/j.celrep.2022.110524","title":"The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Human Genome Research Institute; National Cancer Institute; National Institutes of Health; Advanced Research Projects Agency; York University; Melanoma Research Alliance; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Cancer Research Institute","keywords":"Transcription factor; Cell biology; Transcription (linguistics); Gene; Chemistry; Biology; Genetics","score_opus":0.005838624791526613,"score_gpt":0.2341641728486084,"score_spread":0.2283255480570818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221072882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98454,0.0072048544,0.0074157193,0.000059473834,0.0003132719,0.00017418363,0.000005214216,0.000015576186,0.00027174308],"genre_scores_gemma":[0.99807084,0.00032507838,0.0000782604,0.000016770447,0.000053998534,0.00003515663,0.00015226415,0.00001710812,0.0012505045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991933,0.000039550232,0.00020059336,0.00028036407,0.00012755518,0.00015860471],"domain_scores_gemma":[0.9995916,0.000006574905,0.000089467154,0.00025017475,0.000018913483,0.000043305336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018958504,0.00010317801,0.00006944501,0.000016607371,0.00033405208,0.000038399437,0.000055484295,0.000043258966,0.000014778674],"category_scores_gemma":[0.000017934242,0.000085872925,0.000048145565,0.000037759517,0.000025496864,0.0000027338383,0.00006410446,0.00007656795,1.2419775e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008611741,0.000019129886,0.00551677,0.000013272361,0.0000112340595,0.0000078423955,0.000107922766,0.00041184272,0.9896927,0.0000045736797,0.00080237444,0.0034037235],"study_design_scores_gemma":[0.000134541,0.0000911369,0.006356384,0.0000032852674,0.000024787985,0.00008026058,0.0004474503,0.00025793698,0.9136239,0.0001534297,0.07865491,0.00017195805],"about_ca_topic_score_codex":0.000019288522,"about_ca_topic_score_gemma":0.0000046895425,"teacher_disagreement_score":0.07785253,"about_ca_system_score_codex":0.000014244896,"about_ca_system_score_gemma":0.000020252413,"threshold_uncertainty_score":0.35017964},"labels":[],"label_agreement":null},{"id":"W4221076958","doi":"10.1158/1538-7445.sabcs21-ms1-1","title":"Abstract MS1-1: CRISPR screens to identify novel DNA repair defects synthetic lethal therapies","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"CRISPR; Synthetic lethality; Computational biology; DNA repair; Biology; Context (archaeology); Cancer; Chromatin; Genetics; Cancer research; DNA; Gene","score_opus":0.05246282546040411,"score_gpt":0.43554529167164674,"score_spread":0.38308246621124264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221076958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927824,0.0039022274,0.0012074828,0.0004796211,0.00026146,0.00034718472,0.00008169606,0.00003742965,0.0009004948],"genre_scores_gemma":[0.99757385,0.00016312485,0.00022907564,0.00016129256,0.00031733525,0.00040380462,0.000023431236,0.000046758574,0.0010813342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821067,0.00007756875,0.0001619916,0.0004958358,0.0005124145,0.00054150727],"domain_scores_gemma":[0.9991204,0.00004102216,0.000020603507,0.00052598177,0.00013042956,0.00016153454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008423092,0.00013797425,0.00012706098,0.00013990185,0.00032644797,0.000039607432,0.00039126087,0.00006456605,0.00037879185],"category_scores_gemma":[0.00012785352,0.0001458937,0.00012222822,0.00028559368,0.00007331351,0.000002967622,0.00049989787,0.0003540555,0.000021551703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086197884,0.000054733642,0.00041791573,0.000038012604,0.000057183654,0.000013382125,0.00019620688,0.0027558699,0.98452,0.000043198306,0.010488505,0.0013287737],"study_design_scores_gemma":[0.00045568956,0.00038450063,0.024371877,0.000031419742,0.000011507822,0.000024890394,0.0009065517,0.000052690477,0.7508784,0.00003525225,0.22251633,0.000330915],"about_ca_topic_score_codex":0.0003591396,"about_ca_topic_score_gemma":0.00014659674,"teacher_disagreement_score":0.23364164,"about_ca_system_score_codex":0.000085731765,"about_ca_system_score_gemma":0.00015664523,"threshold_uncertainty_score":0.59493726},"labels":[],"label_agreement":null},{"id":"W4223427248","doi":"10.3390/molecules27082434","title":"Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Induced pluripotent stem cell; Cas9; Genome editing; Green fluorescent protein; Biology; High-content screening; Reporter gene; Embryonic stem cell; Cell biology; Gene knockin; Gene; Genetics; Computational biology; Gene expression; Cell","score_opus":0.030351907815701264,"score_gpt":0.28847400872789597,"score_spread":0.25812210091219473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223427248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7446506,0.0014134396,0.2526798,0.00034200706,0.00031189638,0.00044920752,0.000060351857,0.00004350727,0.000049212733],"genre_scores_gemma":[0.98712206,0.000038686336,0.010343344,0.00043751884,0.00021138972,0.00029355998,0.00068000617,0.00006345567,0.000809991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984953,0.00004162457,0.00039094777,0.000481542,0.0002154039,0.00037517422],"domain_scores_gemma":[0.9993303,0.000012703796,0.00012130455,0.00034773,0.00010207936,0.000085916065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021049537,0.00022830418,0.00019605995,0.00007584066,0.0003121869,0.000034726436,0.00023075136,0.00007348664,0.00001747241],"category_scores_gemma":[0.000024461182,0.00023964002,0.00013961966,0.00008456149,0.000026338741,0.0000026191365,0.00030204476,0.00010371558,0.0000015343644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055614088,0.000056337438,0.00034176253,0.00005836303,0.00006745291,0.00002598257,0.00007279953,0.0033713174,0.99211127,0.00011577304,0.001814192,0.0019091466],"study_design_scores_gemma":[0.0010259515,0.00035603045,0.0020723233,0.000018058032,0.00004001123,0.000029483575,0.00039601608,0.0006315876,0.95453334,0.000033811026,0.040435944,0.00042742363],"about_ca_topic_score_codex":0.000043175893,"about_ca_topic_score_gemma":0.000020925834,"teacher_disagreement_score":0.24247147,"about_ca_system_score_codex":0.000039790375,"about_ca_system_score_gemma":0.000051270858,"threshold_uncertainty_score":0.97722363},"labels":[],"label_agreement":null},{"id":"W4223548728","doi":"10.1126/sciadv.abl4370","title":"Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases","year":2022,"lang":"en","type":"article","venue":"Science Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Clinical trial; Medicine; Induced pluripotent stem cell; Clinical efficacy; Drug; Intensive care medicine; Personalized medicine; Efficacy; Drug development; Bioinformatics; Internal medicine; Oncology; Pharmacology; Biology","score_opus":0.015613010547543694,"score_gpt":0.35036314388035655,"score_spread":0.33475013333281284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223548728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889064,0.000107133266,0.010435398,0.0000039944107,0.00022670958,0.00027169276,0.000022278895,0.0000053837352,0.000021031821],"genre_scores_gemma":[0.98659897,0.0000021271696,0.013180273,0.000021336573,0.00004134249,0.000083158964,0.000051151346,0.000004219773,0.000017437935],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993108,0.0000052481005,0.00015479975,0.00020872813,0.00019419547,0.00012626302],"domain_scores_gemma":[0.9997327,0.000014629484,0.000062994746,0.00008039972,0.00006847776,0.000040795894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017590664,0.00005352308,0.0000681586,0.000031696145,0.00020120248,0.000006279464,0.00013879333,0.0000111735035,0.000005221986],"category_scores_gemma":[0.00007463392,0.000044440596,0.000029532683,0.00014935868,0.00009443087,0.0000074228014,0.00003007953,0.000025771058,9.6415796e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04444001,0.0023418176,0.20967937,0.00018322705,0.0000758386,5.186344e-7,0.00029185502,0.09071027,0.20329115,0.00007349469,0.0002604723,0.448652],"study_design_scores_gemma":[0.03466258,0.009601435,0.06817032,0.000022152864,0.00003713646,9.083765e-7,0.000517516,0.0009913517,0.7706978,0.00005278784,0.11468932,0.0005566976],"about_ca_topic_score_codex":2.3547086e-7,"about_ca_topic_score_gemma":0.0000046431746,"teacher_disagreement_score":0.56740665,"about_ca_system_score_codex":0.000012596165,"about_ca_system_score_gemma":0.00027133158,"threshold_uncertainty_score":0.1812235},"labels":[],"label_agreement":null},{"id":"W4223600966","doi":"10.1038/s41587-022-01308-z","title":"Author Correction: An engineered prime editor with enhanced editing efficiency in plants","year":2022,"lang":"en","type":"erratum","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Prime (order theory); Computational biology; Computer science; Biology; Mathematics; Combinatorics","score_opus":0.0027994837479915096,"score_gpt":0.2588083885117682,"score_spread":0.2560089047637767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223600966","genre_codex":"editorial","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07493038,0.038480658,0.038745802,0.0023638494,0.83316666,0.0025366773,0.00060951523,0.0013041967,0.007862233],"genre_scores_gemma":[0.83821553,0.0012929087,0.0030597153,0.0003250008,0.056980524,0.00043172864,0.008087047,0.00044130458,0.091166236],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978562,0.000043587555,0.0003000796,0.0009616619,0.00028677774,0.0005517193],"domain_scores_gemma":[0.99891853,0.000014234443,0.00014955839,0.0007814248,0.00005702043,0.00007922001],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00019069183,0.00044663975,0.00041012766,0.00041936146,0.000102063736,0.000020172758,0.0006093991,0.00438472,0.00006293771],"category_scores_gemma":[0.00021130756,0.00044204376,0.00007496026,0.0003936869,0.0000885717,0.000003896631,0.00023535748,0.0037971383,0.000003334688],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013296271,0.00015140262,0.000016185277,0.000072007555,0.00008174787,0.000067247245,0.00006812872,0.0011307872,0.2182724,0.000020241938,0.7740276,0.0059593255],"study_design_scores_gemma":[0.00038598225,0.0008526641,0.00008731956,0.00006758587,0.000018325074,0.00010840591,0.00015230956,0.0004958539,0.26053694,0.0000034567906,0.73681694,0.00047420806],"about_ca_topic_score_codex":0.00001493541,"about_ca_topic_score_gemma":0.00020171977,"teacher_disagreement_score":0.77618617,"about_ca_system_score_codex":0.00008256937,"about_ca_system_score_gemma":0.00022872402,"threshold_uncertainty_score":0.9998031},"labels":[],"label_agreement":null},{"id":"W4223601910","doi":"10.1038/s41588-022-01046-7","title":"Genome-edited crops for improved food security of smallholder farmers","year":2022,"lang":"en","type":"article","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Genome Canada; Bill and Melinda Gates Foundation","keywords":"Food security; Sustainability; Biology; Diversification (marketing strategy); Agriculture; Enthusiasm; Agricultural diversification; Natural resource economics; License; Genome; Biotechnology; Business; Economics; Political science; Ecology; Gene; Genetics","score_opus":0.005213833922393772,"score_gpt":0.2637700204765642,"score_spread":0.25855618655417045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223601910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98213047,0.008976387,0.0069023394,0.000096767064,0.00068342214,0.0004872344,0.00052804797,0.000015121764,0.00018019021],"genre_scores_gemma":[0.99535674,0.00014883945,0.0032424743,0.00024109287,0.00032982556,0.000071917246,0.0004117151,0.00004157867,0.00015581194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999029,0.00002316156,0.00021453013,0.00032893324,0.00013393613,0.00027042863],"domain_scores_gemma":[0.99934894,0.000011302303,0.00008003005,0.00036758155,0.00012371047,0.00006843426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014752695,0.00016282368,0.00015880098,0.00005797713,0.00010084983,0.000008424327,0.00028863066,0.00022801298,0.000027504013],"category_scores_gemma":[0.00004091701,0.00018137913,0.00014597822,0.00013650874,0.000036216617,8.5512687e-7,0.00022072709,0.00027779778,2.3734273e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012016224,0.0000778021,0.00048656276,0.00006472952,0.00012465277,4.4968658e-7,0.00012610032,0.0036218811,0.9930413,0.000028325227,0.0011694485,0.0011386028],"study_design_scores_gemma":[0.0016789874,0.0021933669,0.0049317423,0.0000032526211,0.00008494937,0.000018529749,0.00033269348,0.0014705769,0.6007467,0.0002821792,0.38778362,0.00047344685],"about_ca_topic_score_codex":0.0000015865669,"about_ca_topic_score_gemma":0.000009376722,"teacher_disagreement_score":0.39229462,"about_ca_system_score_codex":0.00001722412,"about_ca_system_score_gemma":0.000062211206,"threshold_uncertainty_score":0.7396426},"labels":[],"label_agreement":null},{"id":"W4224245578","doi":"10.1016/j.jbc.2022.101951","title":"The N-terminal domain of the Agrobacterium tumefaciens telomere resolvase, TelA, regulates its DNA cleavage and rejoining activities","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Telomere; Tn3 transposon; Biology; DNA; Telomere-binding protein; Replicon; Agrobacterium tumefaciens; Recombinase; DNA replication; Telomerase; Mutant; Molecular biology; Plasmid; Cell biology; Genetics; Gene; DNA-binding protein; Transformation (genetics); Recombination; Transposable element","score_opus":0.008626590814221636,"score_gpt":0.24543958200392585,"score_spread":0.23681299118970423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224245578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967117,0.0025347744,0.000016846601,0.00019910555,0.00010902117,0.00004624813,0.000022356984,0.0000026953549,0.00035730682],"genre_scores_gemma":[0.9990194,0.00027306334,0.00011345714,0.000039126782,0.00016862086,0.000003566139,0.000003759996,0.0000074047434,0.00037163607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999132,0.0000679918,0.00031351284,0.00014078112,0.00016074399,0.00018501516],"domain_scores_gemma":[0.999389,0.000062479725,0.0002638556,0.00018884176,0.000039565693,0.00005623828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044960453,0.00011860636,0.00016501539,0.000010102312,0.00023511525,0.000019509625,0.00032441484,0.00008646071,0.00002050277],"category_scores_gemma":[0.00014593168,0.00006628403,0.00013855794,0.00006891341,0.00018814817,0.000003200257,0.00036268285,0.0002741243,7.5697876e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011816239,0.00002247813,0.00089355145,0.000020181138,0.000034645553,0.000012422764,0.000056683024,0.00005921561,0.9977042,0.00000554761,0.00047604722,0.00059684855],"study_design_scores_gemma":[0.00024756978,0.00023119016,0.006124771,0.000018285862,0.000013494109,0.0009954658,0.0010263145,0.000009639661,0.9783605,0.00005865422,0.012813393,0.00010077397],"about_ca_topic_score_codex":5.4461725e-7,"about_ca_topic_score_gemma":4.2975566e-7,"teacher_disagreement_score":0.01934377,"about_ca_system_score_codex":0.000015900265,"about_ca_system_score_gemma":0.00004205657,"threshold_uncertainty_score":0.27029845},"labels":[],"label_agreement":null},{"id":"W4224263717","doi":"10.3390/ijms23094640","title":"CRISPR/Cas9-Mediated Mutagenesis of the Granule-Bound Starch Synthase Gene in the Potato Variety Yukon Gold to Obtain Amylose-Free Starch in Tubers","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Amylose; Amylopectin; Starch synthase; Starch; Biochemistry; Polysaccharide; Chemistry; Food science; Biology","score_opus":0.010505137791640237,"score_gpt":0.30271119339965696,"score_spread":0.2922060556080167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224263717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99350196,0.00084946177,0.00270619,0.0022897534,0.00037348134,0.00014886013,0.000044798635,0.0000012559932,0.00008423398],"genre_scores_gemma":[0.9983598,0.000064064174,0.0009028912,0.00058477005,0.000051060404,0.000012630667,0.0000052032296,0.000008282078,0.000011271669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978942,0.00024372284,0.0004075938,0.00020457018,0.0010434113,0.00020645629],"domain_scores_gemma":[0.999346,0.000071245726,0.00014094808,0.0002443651,0.00014691341,0.000050496452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016566592,0.0001103991,0.00012964099,0.00024242669,0.00006803828,0.000046471097,0.0019243236,0.000033642602,0.00001870155],"category_scores_gemma":[0.00033317995,0.00007877245,0.0001264189,0.00052200654,0.00013891493,0.000009511499,0.000417205,0.00020786341,3.3373013e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020705361,0.00014861024,0.0055176266,0.0000063812554,0.000054282875,0.00012804345,0.0012386072,0.09549041,0.8957048,0.00013028864,0.00015918535,0.0012146959],"study_design_scores_gemma":[0.0025326028,0.002034379,0.05297747,0.00008120271,0.000040630428,0.0006142956,0.0065206727,0.0025549247,0.92607236,0.00114339,0.0049825176,0.00044554408],"about_ca_topic_score_codex":0.00021772951,"about_ca_topic_score_gemma":0.00019146623,"teacher_disagreement_score":0.09293549,"about_ca_system_score_codex":0.00006363763,"about_ca_system_score_gemma":0.00024140318,"threshold_uncertainty_score":0.3575904},"labels":[],"label_agreement":null},{"id":"W4224750762","doi":"10.1007/s43441-022-00409-w","title":"Global Regulatory and Public Health Initiatives to Advance Pediatric Drug Development for Rare Diseases","year":2022,"lang":"en","type":"review","venue":"Therapeutic Innovation & Regulatory Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Center for Advancing Translational Sciences; Rare Diseases Clinical Research Network; National Institutes of Health; Ministry of Health, Labour and Welfare; Patient-Centered Outcomes Research Institute; National Organization for Rare Disorders","keywords":"Drug development; Medicine; Clinical trial; Pharmacy; Orphan drug; Pandemic; Public health; Disease; Population; Intensive care medicine; Business; Drug; Family medicine; Environmental health; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty); Nursing; Pharmacology; Pathology","score_opus":0.04255516405409542,"score_gpt":0.3741790676218467,"score_spread":0.3316239035677513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224750762","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0057297363,0.98249066,0.010024527,0.000083249826,0.00039649522,0.0010993222,0.00010118579,0.000036622478,0.0000381732],"genre_scores_gemma":[0.032650445,0.9597361,0.0044070496,0.0011854899,0.0004323732,0.00074837916,0.0005470511,0.00007405196,0.00021905756],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976841,0.0000739837,0.000585621,0.0007614707,0.0004077034,0.00048710866],"domain_scores_gemma":[0.9988348,0.000030340145,0.00031973593,0.00044203084,0.00020178547,0.00017134113],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009859718,0.00032322205,0.00046060752,0.00037647507,0.0005175462,0.000069706235,0.00047078964,0.000072375966,0.000012186664],"category_scores_gemma":[0.00012281234,0.0003162518,0.00007159018,0.0021434305,0.0001775587,0.000024369456,0.00026993826,0.00008590285,0.0000013108148],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006791595,0.000035743717,0.00019174795,0.0015762569,0.000033680903,2.4814008e-7,0.00013287179,0.000032983033,0.00005085858,0.002461643,0.00021243925,0.9952647],"study_design_scores_gemma":[0.00015171448,0.00009419295,0.0047070985,0.00011486536,0.000029910863,0.000009753222,0.0000893683,0.000006356158,0.000047467205,0.000063085965,0.99429804,0.00038812667],"about_ca_topic_score_codex":6.728313e-7,"about_ca_topic_score_gemma":0.000002392695,"teacher_disagreement_score":0.9948766,"about_ca_system_score_codex":0.00027794184,"about_ca_system_score_gemma":0.0030027512,"threshold_uncertainty_score":0.99992895},"labels":[],"label_agreement":null},{"id":"W4225112567","doi":"10.1038/s41556-022-00895-y","title":"Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase","year":2022,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Toronto; SickKids Foundation; Health Sciences North; St. Michael's Hospital; Hospital for Sick Children","funders":"Office of Extramural Research, National Institutes of Health; National Institute of General Medical Sciences; Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; Government of Canada; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada","keywords":"Effector; Kinase; Biology; Cell biology; Phosphatidylinositol; Phosphorylation; PEP group translocation; Phosphatase; Biochemistry; Phosphoenolpyruvate carboxykinase; Enzyme","score_opus":0.00237599305215908,"score_gpt":0.25421372477063914,"score_spread":0.25183773171848006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225112567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97275615,0.023995832,0.00074817194,0.00006649132,0.00044503604,0.0002077963,0.0004422026,0.000023974511,0.0013143461],"genre_scores_gemma":[0.9982153,0.00048082424,0.00020777852,0.00026512664,0.000042906842,0.00007694218,0.00036971612,0.000031680065,0.00030973458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878293,0.00008362884,0.0002529395,0.00044269796,0.00012746542,0.00031036514],"domain_scores_gemma":[0.99940836,0.000041398896,0.000070323484,0.0003486415,0.000052533425,0.00007871858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019222226,0.00020827503,0.00024200094,0.00005433055,0.00010530058,0.0000049706287,0.00033415007,0.0003615737,0.0003162288],"category_scores_gemma":[0.000042988606,0.00021360713,0.00014870352,0.00015441909,0.00006591248,0.0000013398959,0.00016105134,0.00043363136,0.0000031109644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016633478,0.00012750884,0.0012232385,0.000023747543,0.000056502526,0.0000058774785,0.000025600162,0.0004355124,0.99176097,0.000046165784,0.004689081,0.0014394622],"study_design_scores_gemma":[0.00041034076,0.00035157934,0.00024845745,0.0000033672227,0.000030493899,0.000010439933,0.00008056174,0.00005511556,0.9278679,0.000023735061,0.070696004,0.00022199156],"about_ca_topic_score_codex":0.00006650189,"about_ca_topic_score_gemma":0.000008121534,"teacher_disagreement_score":0.06600692,"about_ca_system_score_codex":0.000025836058,"about_ca_system_score_gemma":0.00005648845,"threshold_uncertainty_score":0.8710646},"labels":[],"label_agreement":null},{"id":"W4225126422","doi":"10.2217/pgs-2022-0010","title":"Characterization of the Impact of the <i>MYBBP1A</i> Gene and rs3809849 on Asparaginase Sensitivity and Cellular Functions","year":2022,"lang":"en","type":"article","venue":"Pharmacogenomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Leukemia and Lymphoma Society of Canada; Cancer Research Society","keywords":"Asparaginase; Apoptosis; Allele; CRISPR; Molecular biology; Cell culture; Cell cycle; Mutant; Cell growth; Mesenchymal stem cell; Wild type; Cancer research; Gene; Leukemia; Biology; Chemistry; Lymphoblastic Leukemia; Cell biology; Immunology; Biochemistry; Genetics","score_opus":0.006904262549461898,"score_gpt":0.25957924770752505,"score_spread":0.25267498515806314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225126422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984601,0.00024857925,0.000639304,0.000056362845,0.00013358716,0.0001431893,0.0002860293,0.0000019762715,0.0000308533],"genre_scores_gemma":[0.9996778,0.00009648534,0.000011492411,0.00006438922,0.000047860536,0.0000058643573,0.000035071447,0.000009970347,0.000051087132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996004,0.000060196442,0.00009139567,0.000116523464,0.000056288416,0.000075191994],"domain_scores_gemma":[0.9997198,0.000007583867,0.00006398359,0.00016556823,0.000018628136,0.000024463243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113353075,0.00007313008,0.00006995281,0.0000137653,0.0001021738,0.000003837251,0.000058440455,0.000017994735,0.000006235527],"category_scores_gemma":[0.000006749594,0.00005261849,0.00006280044,0.000058888698,0.00004491057,0.0000013464974,0.00017762173,0.00006874959,9.977949e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038987586,0.000029174387,0.0047200266,0.000007762841,0.000038291513,3.0461382e-7,0.000055493347,0.0078044455,0.98680353,0.0000032102193,0.000037388032,0.0004613845],"study_design_scores_gemma":[0.00024426397,0.00006273777,0.02112941,0.0000015726332,0.00003216885,0.000018525743,0.000013957545,0.0017403673,0.9757652,0.0000028068966,0.0009323598,0.000056614183],"about_ca_topic_score_codex":0.00002223047,"about_ca_topic_score_gemma":0.0000023893995,"teacher_disagreement_score":0.016409384,"about_ca_system_score_codex":0.000011072515,"about_ca_system_score_gemma":0.00002881267,"threshold_uncertainty_score":0.21457197},"labels":[],"label_agreement":null},{"id":"W4225130886","doi":"10.1111/soru.12376","title":"A call to expand disciplinary boundaries so that social scientific imagination and practice are central to quests for ‘responsible’ digital agri‐food innovation","year":2022,"lang":"en","type":"article","venue":"Sociologia Ruralis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Sociotechnical system; Discipline; Sociology; Context (archaeology); Sustainability; Social science; Engineering ethics; Face (sociological concept); Public relations; Political science; Knowledge management; Engineering; Computer science","score_opus":0.02363815488190882,"score_gpt":0.3498671047343982,"score_spread":0.3262289498524894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225130886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9794319,0.00036643835,0.009656273,0.009044982,0.00044516468,0.0004547062,0.00053820806,0.000025824094,0.000036452406],"genre_scores_gemma":[0.99696547,0.0000043140785,0.0011117521,0.00047099328,0.00018108328,0.00017301338,0.0007230789,0.000016375529,0.0003539278],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990053,0.000061852676,0.00014865588,0.00035268636,0.0001435625,0.00028789634],"domain_scores_gemma":[0.9995297,0.000052313073,0.000074000076,0.00012789933,0.00015999888,0.000056068995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037882998,0.00012877677,0.00011488211,0.00009184158,0.0010081789,0.00039936372,0.0001230714,0.00007129405,0.000003790151],"category_scores_gemma":[0.00060624594,0.00013234913,0.000044339806,0.00021748018,0.00018707452,0.000024902121,0.00031171663,0.00008847102,9.795305e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014598801,0.00018896528,0.0071120593,0.00009376872,0.00016140817,0.000006439285,0.020928401,0.001072289,0.885945,0.00317265,0.072706215,0.007152881],"study_design_scores_gemma":[0.002520487,0.0037621248,0.17810662,0.000034250195,0.00011839329,0.000116022624,0.041829363,0.00013818055,0.12513435,0.005750804,0.64082646,0.0016629486],"about_ca_topic_score_codex":0.000007515557,"about_ca_topic_score_gemma":0.000025257037,"teacher_disagreement_score":0.7608107,"about_ca_system_score_codex":0.000067547444,"about_ca_system_score_gemma":0.00015219301,"threshold_uncertainty_score":0.7754199},"labels":[],"label_agreement":null},{"id":"W4225402106","doi":"10.1096/fasebj.2022.36.s1.r2036","title":"<b>I</b> mpact of loss or regain of Equilibrative Nucleoside Transporter (ENT) Subtype‐1 on ENT Subtype‐2 pharmacology in a Novel CRISPR‐Cas9 HEK293‐ENT1KO Cell Model","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Nucleoside; HEK 293 cells; Transporter; Nucleoside transporter; Chemistry; Pharmacology; Biology; Gene; Biochemistry","score_opus":0.01719710759251069,"score_gpt":0.3003252275401658,"score_spread":0.2831281199476551,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225402106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98378205,0.00048370232,0.0146885,0.00022884754,0.00021962257,0.0001898243,0.00011031493,0.000003897102,0.0002932467],"genre_scores_gemma":[0.9987258,0.00018508034,0.0003445757,0.00024291301,0.0001025444,0.000011441636,0.000018559014,0.000028787605,0.0003403306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987432,0.000105997315,0.00042523694,0.00019968853,0.00023354974,0.00029237586],"domain_scores_gemma":[0.999395,0.000036198875,0.00021134283,0.0002242798,0.000049037677,0.00008413313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043711258,0.00017528226,0.0002520161,0.00010347746,0.000077498444,0.000007388708,0.00035572593,0.00006523263,0.00024606247],"category_scores_gemma":[0.000014372035,0.00013067677,0.0001598905,0.0001403968,0.00007698407,0.000005756449,0.000089885085,0.00038456678,0.0000010183448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012325272,0.00029091138,0.00049496815,0.000024509336,0.000058644095,0.00002719458,0.00091141695,0.16187827,0.8344899,0.000028682625,0.00046363942,0.00009933189],"study_design_scores_gemma":[0.0019467182,0.0008813404,0.00060959696,0.00001862382,0.000055648507,0.00010587295,0.000517187,0.010530583,0.9847835,0.0000648193,0.00033207497,0.00015408017],"about_ca_topic_score_codex":0.000022026254,"about_ca_topic_score_gemma":0.000025288862,"teacher_disagreement_score":0.1513477,"about_ca_system_score_codex":0.00005215209,"about_ca_system_score_gemma":0.000253266,"threshold_uncertainty_score":0.53288436},"labels":[],"label_agreement":null},{"id":"W4225421495","doi":"10.1096/fasebj.2022.36.s1.0i111","title":"CRISPR sensors for signaling","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Muscular Dystrophy Canada","funders":"","keywords":"CRISPR; Computational biology; Computer science; Biology; Genetics; Gene","score_opus":0.0115735099598137,"score_gpt":0.2869184940291691,"score_spread":0.27534498406935537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225421495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.950492,0.00094157347,0.04752709,0.00035392185,0.00039099067,0.00010338688,0.000017170902,0.0000054145144,0.00016845214],"genre_scores_gemma":[0.9976803,0.0000301906,0.0007379399,0.00022069148,0.0005234983,0.000016672398,0.000010585178,0.0000146946895,0.00076543016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995171,0.00003873935,0.00010507044,0.00008319825,0.0000965604,0.00015937121],"domain_scores_gemma":[0.99975634,0.000015744312,0.000038447415,0.00011948232,0.000027722235,0.000042252243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003646327,0.000062146086,0.000052153537,0.000019512785,0.00040756393,0.000021955404,0.00016947971,0.00001697808,0.00007704194],"category_scores_gemma":[0.000028841716,0.00004808375,0.000094782146,0.000035044097,0.000014316359,7.902339e-7,0.00006807373,0.00013607896,0.0000013432601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041064897,0.000008999725,0.000071622504,0.000002641554,0.000029980714,0.0000026646558,0.000086294785,0.049984887,0.9451176,0.000025716452,0.0038295342,0.00079899025],"study_design_scores_gemma":[0.00037702385,0.00022021237,0.00006089124,0.0000018618379,0.000022287028,0.00041079315,0.00069874566,0.0009652162,0.9185356,0.00014699127,0.07845914,0.000101214006],"about_ca_topic_score_codex":0.0000011042963,"about_ca_topic_score_gemma":5.218975e-7,"teacher_disagreement_score":0.07462961,"about_ca_system_score_codex":0.000010511844,"about_ca_system_score_gemma":0.000029702021,"threshold_uncertainty_score":0.31346935},"labels":[],"label_agreement":null},{"id":"W4226067321","doi":"10.1038/s41598-021-02986-6","title":"CRISPR/Cas9-mediated base-editing enables a chain reaction through sequential repair of sgRNA scaffold mutations","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Institute of Medical Science, University of Tokyo; Japan Society for the Promotion of Science","keywords":"CRISPR; Cas9; Subgenomic mRNA; Biology; Genome editing; Computational biology; Chain reaction; Gene; Genetics; Cell biology; Chemistry","score_opus":0.013631759002592163,"score_gpt":0.2897770865377464,"score_spread":0.27614532753515425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226067321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839718,0.0009891501,0.0068694,0.000080072656,0.0055421325,0.00017313886,0.000018791477,0.00006705433,0.0022885094],"genre_scores_gemma":[0.99386615,0.000027808454,0.0031765904,0.000025103034,0.00033445543,0.000016723498,0.0008188652,0.000020679354,0.0017136482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834174,0.000045504687,0.0004572543,0.00062186096,0.0002830869,0.00025057423],"domain_scores_gemma":[0.998661,0.000014601937,0.00020602769,0.0006480008,0.00039929326,0.00007111182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058714877,0.00012972052,0.0001500222,0.00006383203,0.00016457865,0.000053521733,0.00006329327,0.000107982174,0.000050181334],"category_scores_gemma":[0.0008220795,0.00013848854,0.00016520647,0.00034685625,0.00011795337,0.00000971212,0.00008576902,0.00006726505,0.000003731925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038322664,0.00005247743,0.001009828,0.000047013607,0.00003896921,0.00014373213,0.00012621639,0.0008051556,0.98968655,0.000028805198,0.007890756,0.00016665673],"study_design_scores_gemma":[0.00011862113,0.000027516984,0.0004396078,0.000036611604,0.000032621356,0.00020301319,0.0004124497,0.00033289127,0.9380212,0.00024626695,0.05999278,0.00013642025],"about_ca_topic_score_codex":0.00004695508,"about_ca_topic_score_gemma":0.00008301865,"teacher_disagreement_score":0.052102022,"about_ca_system_score_codex":0.000018640272,"about_ca_system_score_gemma":0.00020876726,"threshold_uncertainty_score":0.5647399},"labels":[],"label_agreement":null},{"id":"W4226243051","doi":"10.3389/fnut.2022.856491","title":"Gene-Edited Meat: Disentangling Consumers' Attitudes and Potential Purchase Behavior","year":2022,"lang":"en","type":"article","venue":"Frontiers in Nutrition","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Livestock; Sustainability; Consumption (sociology); Business; Marketing; Production (economics); Food security; Animal welfare; Quality (philosophy); Agriculture; Food processing; Biotechnology; Economics; Food science; Biology","score_opus":0.0049394678584048475,"score_gpt":0.2601554022859268,"score_spread":0.255215934427522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226243051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9759273,0.00934665,0.013618177,0.00004216112,0.0007212427,0.00024502462,0.000071322705,0.000012054276,0.000016054619],"genre_scores_gemma":[0.99330395,0.0012509571,0.0047193426,0.00003438815,0.00012603975,0.00014208756,0.0003656618,0.000013921194,0.000043617285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940574,0.000028353812,0.00011273113,0.00021401982,0.000095341675,0.00014379788],"domain_scores_gemma":[0.9998133,0.0000016023353,0.000021237722,0.00010627063,0.000013514778,0.000044028297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006579511,0.00008371243,0.00008521543,0.00008345659,0.000094857685,0.000013366566,0.00006425458,0.000046114532,0.000013364624],"category_scores_gemma":[0.0000078263665,0.000105785155,0.000035785662,0.000070723625,0.00003555166,0.0000029266844,0.00008259156,0.00008412408,2.5295247e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002665845,0.0005698189,0.22104187,0.0002126537,0.00005936679,0.000110388,0.00011753561,0.0014354982,0.7617527,0.000010820064,0.007802322,0.0066204295],"study_design_scores_gemma":[0.014697912,0.0012052904,0.08420125,0.00015047539,0.00029669725,0.0005811289,0.0041779685,0.008339587,0.83811677,0.00031428365,0.046131644,0.0017870105],"about_ca_topic_score_codex":0.000006866926,"about_ca_topic_score_gemma":0.0000040313353,"teacher_disagreement_score":0.13684063,"about_ca_system_score_codex":0.000020732186,"about_ca_system_score_gemma":0.000009833075,"threshold_uncertainty_score":0.43137935},"labels":[],"label_agreement":null},{"id":"W4226270092","doi":"10.1007/978-1-0716-2063-2_14","title":"Purification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) from HeLa Cells","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"DNA-PKcs; Protein subunit; Ku70; Recombinant DNA; HeLa; Molecular biology; DNA; Protein kinase A; Biology; Chemistry; Kinase; Cell biology; Biochemistry; Gene; Cell; DNA repair","score_opus":0.01288007102683703,"score_gpt":0.3612527270416305,"score_spread":0.34837265601479345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226270092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49921888,0.0013494561,0.49865758,0.000050804283,0.00018336333,0.00031067422,0.00006613882,0.000009548955,0.00015353369],"genre_scores_gemma":[0.7263128,0.00004027114,0.27256307,0.000102676466,0.000050013674,0.00023540347,0.0004378489,0.000039757295,0.00021815542],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785525,0.00081267994,0.00039819788,0.00052577275,0.000114371396,0.0002937188],"domain_scores_gemma":[0.999085,0.00003779508,0.00012910843,0.00064388127,0.00004332648,0.000060858343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008569841,0.0001957985,0.0002704374,0.00014072146,0.00005135147,0.00000652816,0.0004065404,0.00016930827,0.00008328944],"category_scores_gemma":[0.00014177765,0.00021963917,0.00011126721,0.00020714432,0.00007965609,0.0000016442106,0.00035911246,0.00021303256,0.0000030121248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052680018,0.00009348661,0.0002126541,0.000017657334,0.000042813677,0.000012782347,0.000070925045,0.0014171773,0.99210715,0.00019984308,0.000017071812,0.005755761],"study_design_scores_gemma":[0.00047121602,0.00026362162,0.00017372979,0.000005795893,0.000021129374,0.0000069732464,0.0001105765,0.0002848044,0.99152386,0.0008638125,0.0060503385,0.00022411876],"about_ca_topic_score_codex":0.00017565729,"about_ca_topic_score_gemma":0.000019778478,"teacher_disagreement_score":0.2270939,"about_ca_system_score_codex":0.000037513757,"about_ca_system_score_gemma":0.00006569137,"threshold_uncertainty_score":0.89566255},"labels":[],"label_agreement":null},{"id":"W4226280654","doi":"10.1038/s41587-021-01201-1","title":"Saturation variant interpretation using CRISPR prime editing","year":2022,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; SickKids Foundation; Mount Sinai Hospital; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Biology; Locus (genetics); Genetics; Missense mutation; Computational biology; Gene; Phenotype","score_opus":0.0038303191431189785,"score_gpt":0.28369675855301535,"score_spread":0.27986643940989636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226280654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68906087,0.0034580168,0.3028708,0.0016278899,0.002140047,0.00030603164,0.00003070292,0.00014699464,0.00035865518],"genre_scores_gemma":[0.99397343,0.000022537126,0.005230528,0.00029053268,0.00028015816,0.000016265272,0.00010616845,0.000019796087,0.00006058149],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992244,0.000034097167,0.00014221064,0.00030423215,0.00010800387,0.00018704224],"domain_scores_gemma":[0.99961114,0.000005742356,0.00006611523,0.0002621173,0.000032653068,0.000022232449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013803101,0.000108636516,0.00009194389,0.00011285263,0.00015189046,0.000011376175,0.0001861282,0.0004581682,0.000027124834],"category_scores_gemma":[0.00010878176,0.00012301674,0.000048736318,0.00017212874,0.000030698182,0.0000027686297,0.00024379388,0.00057056884,0.0000015101983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030269563,0.000017346534,0.00007499652,0.000005829722,0.000023427501,0.000007057492,0.000031464937,0.002490957,0.9905221,0.00060655,0.00054177816,0.0056482577],"study_design_scores_gemma":[0.00029605214,0.00023996885,0.00031038746,0.000006131774,0.000022319233,0.00029416315,0.00024216087,0.015500335,0.9275068,0.00017232352,0.055187285,0.00022204428],"about_ca_topic_score_codex":0.000006932121,"about_ca_topic_score_gemma":0.0000062701915,"teacher_disagreement_score":0.30491257,"about_ca_system_score_codex":0.00003953998,"about_ca_system_score_gemma":0.00003495592,"threshold_uncertainty_score":0.5016477},"labels":[],"label_agreement":null},{"id":"W4226322571","doi":"10.1016/j.bpj.2021.11.2245","title":"Nav1.5 knockout in iPSCs: a novel approach to study Nav1.5 variants in a human cardiomyocyte environment","year":2022,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Induced pluripotent stem cell; Reprogramming; CRISPR; Somatic cell; Sodium channel; Knockout mouse; Biology; Cell biology; Nav1.5; Computational biology; Neuroscience; Cell; Genetics; Chemistry; Embryonic stem cell; Gene; Sodium","score_opus":0.012742047734679657,"score_gpt":0.2774207333493896,"score_spread":0.26467868561471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226322571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927484,0.00008181089,0.006476646,0.00003688766,0.0000996897,0.00029891494,0.000011912418,0.000004263186,0.00024151412],"genre_scores_gemma":[0.9986611,0.000008705079,0.00077422155,0.000069122456,0.00029042052,0.00009077201,0.000011634573,0.000023859664,0.00007017903],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99867135,0.00009326812,0.00028489804,0.0003513316,0.00028180066,0.00031732023],"domain_scores_gemma":[0.99956447,0.0000046186424,0.000043291217,0.0002471987,0.000009152524,0.00013125868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003213891,0.00016482359,0.00021765425,0.000113018374,0.00012365791,0.000028321188,0.00028584158,0.000042950538,0.000017653223],"category_scores_gemma":[0.00001099336,0.00016943313,0.000099530094,0.00017020563,0.000016087168,0.0000030651481,0.0003641463,0.00035090317,0.0000037982525],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007298095,0.0015791882,0.0014997803,0.0000041704934,0.000051066196,0.000046245554,0.0005261011,0.032929167,0.9622335,0.000019417139,0.00005407243,0.0009843389],"study_design_scores_gemma":[0.0186553,0.008012975,0.7073151,0.000055224453,0.00015280787,0.0011296986,0.008727559,0.0059149535,0.21990854,0.00010797856,0.02739694,0.0026229608],"about_ca_topic_score_codex":0.000032152235,"about_ca_topic_score_gemma":0.0000038535286,"teacher_disagreement_score":0.74232495,"about_ca_system_score_codex":0.0000917463,"about_ca_system_score_gemma":0.000028607432,"threshold_uncertainty_score":0.6909283},"labels":[],"label_agreement":null},{"id":"W4229853727","doi":"10.17504/protocols.io.x38fqrw","title":"Tranfection of sgRNA using SpCas9 containing plasmids to generate cell lines with Cas9 v2","year":2019,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Cas9; Ribonucleoprotein; Electroporation; Plasmid; Subgenomic mRNA; Nuclease; CRISPR; Guide RNA; Transfection; Genome editing; Biology; Cell biology; RNA; Computational biology; Molecular biology; Chemistry; Cell culture; Genetics; DNA; Gene","score_opus":0.013187473528598278,"score_gpt":0.2948909751810117,"score_spread":0.2817035016524134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229853727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7783168,0.00040289012,0.21936373,0.000013763687,0.00037052276,0.00028901282,0.00002226856,0.000014506488,0.0012065021],"genre_scores_gemma":[0.98486257,0.00008546875,0.013823733,0.000052824387,0.000325718,0.000013062254,0.00009083408,0.000052123694,0.0006936762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988893,0.000022344739,0.0002711841,0.00046991484,0.00012089684,0.00022631657],"domain_scores_gemma":[0.99926484,0.000007288676,0.00009996931,0.0004087057,0.00013633489,0.00008284514],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000114266215,0.00027977536,0.0003075464,0.00008808911,0.000027535516,0.000025574216,0.0001412945,0.00029069773,0.000017836872],"category_scores_gemma":[0.000010168504,0.00025144088,0.000107675914,0.000064569824,0.000020417887,0.0000014182143,0.0001964165,0.00016574527,0.0000030214862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007897824,0.000017893246,0.0007366859,0.0001509162,0.00005857237,0.0000017558029,0.00005426717,0.39877018,0.59979945,0.0000028398065,0.000060051436,0.00026841965],"study_design_scores_gemma":[0.00043935506,0.00046909085,0.00026883566,0.000094845105,0.00007859374,0.000019670939,0.0000810258,0.011698497,0.9851004,0.0000029069115,0.0013821962,0.00036459696],"about_ca_topic_score_codex":0.00023287546,"about_ca_topic_score_gemma":0.00012271652,"teacher_disagreement_score":0.3870717,"about_ca_system_score_codex":0.00001879944,"about_ca_system_score_gemma":0.00012976787,"threshold_uncertainty_score":0.9999938},"labels":[],"label_agreement":null},{"id":"W4230044286","doi":"10.3410/f.1160909.621341","title":"Faculty Opinions recommendation of Genomic sequencing reveals regulatory mutations and recombinational events in the widely used MC4100 lineage of Escherichia coli K-12.","year":2009,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Lineage (genetic); Genetics; Biology; Escherichia coli; Mutation; DNA sequencing; Gene; Computational biology","score_opus":0.023599353963600647,"score_gpt":0.3497300875433028,"score_spread":0.3261307335797022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230044286","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00066042686,0.0013856153,0.00012136964,0.021889668,0.00023945521,0.0010120614,0.9746682,0.000006001369,0.000017225477],"genre_scores_gemma":[0.002297692,0.00039730204,0.00094896025,0.0010948897,0.00011901009,0.000093775714,0.9948634,0.000015726591,0.00016925513],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972325,0.00037083152,0.0011906407,0.00041796506,0.0005887801,0.00019927787],"domain_scores_gemma":[0.9968292,0.00008533287,0.0008678289,0.00079420337,0.0013287737,0.000094649935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012985786,0.00030231255,0.00050390366,0.00019303754,0.00009983696,0.000025736033,0.0007546843,0.00043845532,0.000031160907],"category_scores_gemma":[0.002034438,0.00021106773,0.00025979153,0.00059866946,0.0001641329,0.000024565927,0.00018244526,0.0004455347,0.000001648563],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000092860555,0.0001535039,0.000030233656,0.0018150759,0.0000705836,9.249933e-8,0.00014961357,0.000007839587,0.0010337688,0.00007277612,0.99625397,0.00040325423],"study_design_scores_gemma":[0.000598499,0.00014220944,0.02575024,0.0024737287,0.00009146721,0.00001693406,0.000055560078,0.000026570922,0.00042125184,0.000041183415,0.97017145,0.0002108975],"about_ca_topic_score_codex":0.000028119457,"about_ca_topic_score_gemma":0.000015531867,"teacher_disagreement_score":0.026082514,"about_ca_system_score_codex":0.0000570847,"about_ca_system_score_gemma":0.00035853608,"threshold_uncertainty_score":0.8607092},"labels":[],"label_agreement":null},{"id":"W4231350888","doi":"10.1038/nbt.2098","title":"Recent patent applications related to gene and DNA synthesis","year":2012,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Computational biology; DNA; Gene; Genetics; Biology","score_opus":0.005707125862876884,"score_gpt":0.26414380864655473,"score_spread":0.2584366827836779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231350888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.948797,0.036299456,0.008753086,0.0047482573,0.0003157437,0.0004538535,0.000025133904,0.00011776208,0.000489726],"genre_scores_gemma":[0.9924394,0.002953878,0.0040166928,0.0002501647,0.00009311214,0.000097717966,0.000023336577,0.000018054528,0.00010764765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993523,0.000010155242,0.00010781684,0.0002387128,0.00004806718,0.00024294386],"domain_scores_gemma":[0.99952865,0.000007718867,0.000021709606,0.00032477404,0.000027151758,0.000089991976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009151923,0.00010885921,0.00009372206,0.00007586112,0.000043283075,0.000004704383,0.00011937166,0.00085288315,0.000012161231],"category_scores_gemma":[0.000091331305,0.00010344454,0.000024539706,0.0001567674,0.00003791915,0.0000012371027,0.00012928159,0.0002105797,0.00001757241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000744703,0.000026652717,0.00037884727,0.0000051929733,0.000027204187,3.6909833e-7,0.00000968706,0.000007611074,0.9207814,0.0009106207,0.0005897284,0.07725526],"study_design_scores_gemma":[0.0000540587,0.000028869352,0.0012939082,0.0000020384607,0.000010112619,0.000027862387,0.000012202857,0.0000035492362,0.6260357,0.0000290053,0.3724142,0.000088491426],"about_ca_topic_score_codex":8.738858e-7,"about_ca_topic_score_gemma":0.000002380009,"teacher_disagreement_score":0.37182447,"about_ca_system_score_codex":0.000010413618,"about_ca_system_score_gemma":0.0000084236535,"threshold_uncertainty_score":0.6578216},"labels":[],"label_agreement":null},{"id":"W4231586227","doi":"10.1016/j.nmd.2020.08.284","title":"DMD – THERAPY","year":2020,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Dystrophin; Myogenesis; Duchenne muscular dystrophy; CRISPR; Biology; HEK 293 cells; Utrophin; Reprogramming; Cell biology; Muscular dystrophy; mdx mouse; Genome editing; Bioinformatics; Computational biology; Genetics; Gene; Myocyte","score_opus":0.008884208831898223,"score_gpt":0.26285044367238575,"score_spread":0.2539662348404875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231586227","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9731484,0.0028314241,0.01931897,0.0020371443,0.00016037785,0.0001994658,0.00000406305,0.000054435885,0.002245742],"genre_scores_gemma":[0.99620897,0.001331307,0.00021430236,0.0019717596,0.00015354026,0.00001056279,0.000025483474,0.00003103717,0.000053064876],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99937475,0.000020646668,0.00008513488,0.0002679365,0.00009045179,0.00016110919],"domain_scores_gemma":[0.99967754,0.0000027252347,0.000014829134,0.00019999153,0.000012163891,0.00009277662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002611358,0.00011535195,0.00007561847,0.000012049056,0.000034491604,0.0000134628235,0.0001470281,0.00005368544,0.00003786429],"category_scores_gemma":[0.00003540818,0.00011490816,0.00010625871,0.00007791786,0.000023714685,0.0000013557541,0.000045793877,0.000063151434,0.000023435681],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004423604,0.00003685124,0.0024595566,0.000015090839,0.000045624307,0.0000027700019,0.00011196627,0.0021505256,0.95840925,0.00003298179,0.0034244172,0.033266723],"study_design_scores_gemma":[0.0009778563,0.00053207914,0.009617029,0.0000020411385,0.000009028502,0.000003212981,0.000056412333,0.00048518437,0.14811964,0.00003491696,0.8398582,0.00030439708],"about_ca_topic_score_codex":0.0000034189645,"about_ca_topic_score_gemma":0.000004144837,"teacher_disagreement_score":0.83643377,"about_ca_system_score_codex":0.0000011029682,"about_ca_system_score_gemma":0.000012810677,"threshold_uncertainty_score":0.4685819},"labels":[],"label_agreement":null},{"id":"W4232161844","doi":"10.1139/bcb-2017-0050","title":"Special issue: Discovery and development of the CRISPR–Cas9 system / Numéro spécial : Découverte et mise au point du système CRISPR–Cas9","year":2017,"lang":"fr","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Biology; Computational biology; Computer science; Genetics; Gene","score_opus":0.007934609034577008,"score_gpt":0.26761976475995347,"score_spread":0.2596851557253765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232161844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9623117,0.012525096,0.0017312663,0.0011694714,0.0070083323,0.0003928972,0.0002999802,0.000014964162,0.0145462975],"genre_scores_gemma":[0.9845439,0.0012910796,0.00041432428,0.000073656935,0.008829872,0.000019906409,0.0000773697,0.000035326204,0.0047145546],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978239,0.000110073874,0.0005854733,0.0007736018,0.00013064838,0.00057632383],"domain_scores_gemma":[0.9984011,0.00003852221,0.00038797333,0.0008608489,0.00010051616,0.00021101933],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041819896,0.0004915654,0.0005096086,0.000026453119,0.0005883534,0.00011965713,0.0005380803,0.00074523455,0.000056463785],"category_scores_gemma":[0.00012598294,0.0004192021,0.00016587014,0.000038504808,0.0007700703,0.000017520175,0.0008603818,0.00025057152,0.0000054545962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026293262,0.00018473691,0.008346971,0.002648983,0.00023957505,0.000019388359,0.0008991218,0.000012510175,0.9620254,0.00022864867,0.015549647,0.009582079],"study_design_scores_gemma":[0.00096368545,0.00011632488,0.0034403899,0.00023204704,0.00009380701,0.00010980159,0.0011303567,0.00004631838,0.76456684,0.000019397543,0.22881971,0.00046130974],"about_ca_topic_score_codex":0.00016477196,"about_ca_topic_score_gemma":0.00010539806,"teacher_disagreement_score":0.21327005,"about_ca_system_score_codex":0.00010258268,"about_ca_system_score_gemma":0.00054576364,"threshold_uncertainty_score":0.99982595},"labels":[],"label_agreement":null},{"id":"W4232445201","doi":"10.1038/s41580-020-00304-y","title":"Publisher Correction: Applications of CRISPR–Cas in agriculture and plant biotechnology","year":2020,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Biotechnology; Agriculture; Computational biology; Agricultural biotechnology; Biology; Genetics; Gene; Ecology","score_opus":0.007342585220813724,"score_gpt":0.3200395069437431,"score_spread":0.3126969217229294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232445201","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000002246912,0.9895102,0.0074996827,0.000069826696,0.00052622013,0.0014065312,0.000043661752,0.000017649616,0.00092399074],"genre_scores_gemma":[0.00013123671,0.997007,0.00094266975,0.00012090142,0.0001488464,0.0003476166,0.0011376893,0.0000437093,0.0001203329],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997815,0.0002217319,0.00075627246,0.00084087224,0.00006736283,0.00029877445],"domain_scores_gemma":[0.99888366,0.000028281893,0.00038092196,0.00056105305,0.000048763315,0.000097310134],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00021139455,0.00050713134,0.0016191816,0.00020756856,0.000026343241,0.000013738526,0.00043259267,0.0026368077,0.000006769945],"category_scores_gemma":[0.00014778695,0.0003874644,0.00039468353,0.0005993367,0.00010570204,0.0000024957535,0.00026498013,0.0011150002,0.000008231848],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000049994696,0.000048306567,0.000008886562,0.005913614,0.000083537285,0.000012450021,0.000007989408,0.0000021242881,0.008623608,0.00019294588,0.007904468,0.97719705],"study_design_scores_gemma":[0.00013759006,0.00012406487,0.0000010844715,0.0006650678,0.00020375226,0.00009494853,0.0000062316776,0.000001608548,0.0037193007,0.000021328678,0.9946679,0.00035712734],"about_ca_topic_score_codex":0.0000071014642,"about_ca_topic_score_gemma":0.0000213091,"teacher_disagreement_score":0.9867634,"about_ca_system_score_codex":0.000026165202,"about_ca_system_score_gemma":0.000095009265,"threshold_uncertainty_score":0.9998577},"labels":[],"label_agreement":null},{"id":"W4233365113","doi":"10.26434/chemrxiv-2021-7pdz9","title":"CRISPR-Click Enables Multi-Gene Editing with Modular Synthetic sgRNAs","year":2021,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Deutsche Forschungsgemeinschaft","keywords":"CRISPR; Cas9; Guide RNA; Computational biology; Genome editing; Gene; Biology; Subgenomic mRNA; Genetics","score_opus":0.011632961728699423,"score_gpt":0.2730117855664244,"score_spread":0.261378823837725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233365113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85991806,0.006640895,0.13195238,0.000111303794,0.00062344025,0.00029110978,0.000011741315,0.00006284206,0.00038820226],"genre_scores_gemma":[0.98083144,0.0008340142,0.015990373,0.000095685544,0.0010474115,0.00010251399,0.00048559712,0.00011934247,0.00049364025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997992,0.00003613178,0.00031401563,0.00097577844,0.00021114259,0.0004709312],"domain_scores_gemma":[0.9984431,0.000011461921,0.00013124173,0.0010691546,0.00017988739,0.00016510836],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016831345,0.00047670407,0.00040156022,0.000065929555,0.00008314139,0.00011129261,0.00038997107,0.0004908601,0.000042363205],"category_scores_gemma":[0.00012430342,0.00046567988,0.0002187531,0.00009176895,0.00008426682,0.0000027278668,0.00068658096,0.00041644892,0.0000074420186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017536615,0.00009881641,0.00059871405,0.0003754139,0.00025708912,0.000061944724,0.00012858209,0.019026196,0.978339,0.0000027540486,0.00032850605,0.0007654101],"study_design_scores_gemma":[0.0004413154,0.00005241258,0.0005406178,0.00023704866,0.000102820406,0.000060168866,0.00020174457,0.0016461287,0.9901415,0.000008118956,0.005986105,0.000582022],"about_ca_topic_score_codex":0.000044896595,"about_ca_topic_score_gemma":0.000032760676,"teacher_disagreement_score":0.120913334,"about_ca_system_score_codex":0.00002845978,"about_ca_system_score_gemma":0.00014656232,"threshold_uncertainty_score":0.99977946},"labels":[],"label_agreement":null},{"id":"W4233602549","doi":"10.1177/0270467607300633","title":"Biotrespass","year":2007,"lang":"en","type":"article","venue":"Bulletin of Science Technology & Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Trespass; Plaintiff; Liability; Action (physics); Law and economics; Damages; Cause of action; Tort; Law; Business; Political science; Sociology","score_opus":0.004460523016843245,"score_gpt":0.27981933951647275,"score_spread":0.2753588164996295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233602549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97496206,0.0009099639,0.019982664,0.001416445,0.00013526987,0.00008417678,0.0000020681537,0.000050754825,0.0024566215],"genre_scores_gemma":[0.9792008,0.00012715698,0.020111134,0.000151299,0.000043857734,0.000002663234,0.000001347412,0.0000074539157,0.00035430244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990859,0.0000021801877,0.00015433927,0.00028423857,0.00014976549,0.0003235696],"domain_scores_gemma":[0.9994638,0.0000073843157,0.00004852756,0.00032605196,0.00010511557,0.000049149705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006757174,0.000085863605,0.00008792244,0.00009600531,0.00011446549,0.0000054217703,0.00043624395,0.00017751039,0.000025805155],"category_scores_gemma":[0.000104098355,0.00008339833,0.0000777435,0.00056142436,0.0019569113,7.34707e-7,0.0002151634,0.00009076825,0.000009553044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003916316,0.000020574604,0.0015086622,0.0000055311716,0.0000075966077,5.817589e-7,0.000046552203,0.000023821869,0.9889762,0.00039298876,0.0057944683,0.0032191547],"study_design_scores_gemma":[0.0001300405,0.000088235916,0.0019649044,0.000005224478,0.0000034533402,0.000010644243,0.00071355136,0.000010531265,0.8333122,0.00005297205,0.16362227,0.000085966305],"about_ca_topic_score_codex":0.000006769511,"about_ca_topic_score_gemma":0.0000026319951,"teacher_disagreement_score":0.15782781,"about_ca_system_score_codex":0.000013497218,"about_ca_system_score_gemma":0.00004931383,"threshold_uncertainty_score":0.72103214},"labels":[],"label_agreement":null},{"id":"W4234556469","doi":"10.1093/nar/gky976","title":"Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases","year":2018,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Western University","funders":"Argonne National Laboratory; Natural Sciences and Engineering Research Council of Canada; Industrial Macromolecular Crystallography Association Collaborative Access Team; Canadian Institutes of Health Research; Office of Science; U.S. Department of Energy","keywords":"Homing endonuclease; Biology; Active site; Cleavage (geology); DNA; Cleavage factor; Genome; Genetics; Cleavage and polyadenylation specificity factor; Reprogramming; Scissile bond; Endonuclease; Biochemistry; Computational biology; Enzyme; Polyadenylation; Gene; RNA","score_opus":0.03837344545888637,"score_gpt":0.3720029924082638,"score_spread":0.3336295469493774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234556469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99211365,0.00033943975,0.00090039254,0.000042629417,0.000073688425,0.00018949555,0.000032602078,0.000018280823,0.0062898477],"genre_scores_gemma":[0.99757993,0.00018379772,0.001028671,0.0000150963915,0.0003369745,0.000011370542,0.000020243768,0.000032104956,0.00079178036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984179,0.00012391299,0.00020571022,0.00039946468,0.00042029214,0.00043268627],"domain_scores_gemma":[0.99885625,0.00004804972,0.000045780846,0.00056765985,0.00036678635,0.00011545369],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005249009,0.0001331832,0.00016027504,0.00012962494,0.00016683638,0.000045556448,0.00040612722,0.00015819904,0.00013955873],"category_scores_gemma":[0.00042790137,0.00013298514,0.00007107165,0.00028425356,0.00041455525,0.000016294456,0.0004680868,0.00020519119,0.00006492985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020305977,0.000046805337,0.0031576827,0.000046586927,0.00003896802,0.00000336625,0.00032266113,0.0000110756355,0.9890836,0.00019785714,0.0020143848,0.0048739426],"study_design_scores_gemma":[0.0003049668,0.0004843779,0.053399112,0.00004442392,0.000007750258,0.0000061337837,0.0002892861,0.00011415677,0.9397508,0.00023774712,0.0052266945,0.00013453748],"about_ca_topic_score_codex":0.000117465075,"about_ca_topic_score_gemma":0.00019385903,"teacher_disagreement_score":0.05024143,"about_ca_system_score_codex":0.000022940034,"about_ca_system_score_gemma":0.00006945356,"threshold_uncertainty_score":0.54229766},"labels":[],"label_agreement":null},{"id":"W4234654156","doi":"10.1007/978-1-4614-6170-8_100171","title":"Edit Networks","year":2014,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Computer science","score_opus":0.00491106256038255,"score_gpt":0.24254431125526646,"score_spread":0.23763324869488392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234654156","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000014328146,0.0016803158,0.21534427,0.000024797806,0.00055067946,0.00007505712,0.000003815063,0.000021055132,0.7822857],"genre_scores_gemma":[0.014053876,0.00065146346,0.00047965426,0.0002878245,0.0033175815,0.000003860248,0.00022118824,0.00006690781,0.98091763],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993682,0.0000023582559,0.00013287745,0.000272039,0.00007248093,0.00015207313],"domain_scores_gemma":[0.9995006,0.0000042726006,0.00003445869,0.00036079792,0.00003179593,0.000068098605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051643892,0.0002029349,0.00014691096,0.000023020668,0.000020912697,0.000011532436,0.00012984217,0.00041330868,0.00036005638],"category_scores_gemma":[0.0000059500503,0.00019551776,0.00011868519,0.0000040991863,0.000025747082,1.6084341e-7,0.000089338915,0.00012263589,0.00006853173],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040571904,0.000011727571,0.00002223235,0.00009217617,0.00041713312,0.000012068693,0.000009926779,0.010990672,0.013076858,0.068799496,0.8451275,0.06139959],"study_design_scores_gemma":[0.000093374045,0.00007501175,0.0000057137604,0.000015857628,0.000021580236,0.000008588294,5.6551704e-7,0.0003257323,0.0017370726,0.00016582973,0.9972867,0.00026399267],"about_ca_topic_score_codex":0.0000013069396,"about_ca_topic_score_gemma":0.000011074213,"teacher_disagreement_score":0.21486461,"about_ca_system_score_codex":0.000004335148,"about_ca_system_score_gemma":0.0000139873255,"threshold_uncertainty_score":0.79729825},"labels":[],"label_agreement":null},{"id":"W4235263872","doi":"10.1038/jid.2012.84","title":"Genetic Diseases/Gene Regulation/Gene Therapy","year":2012,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Gene; Genetic enhancement; Genetics; Biology; Computational biology; Bioinformatics","score_opus":0.013006259653988097,"score_gpt":0.28462470301441134,"score_spread":0.27161844336042323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4235263872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9739359,0.012999122,0.012099825,0.00040710342,0.0003740874,0.00008169106,0.000008060248,0.0000057070047,0.0000884958],"genre_scores_gemma":[0.99005157,0.00047016746,0.008226207,0.0005004861,0.0006567973,0.0000050067515,0.000019982906,0.000022853148,0.000046957462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896944,0.000110985304,0.00039176448,0.000116311254,0.00013715532,0.00027436554],"domain_scores_gemma":[0.9990876,0.0000222081,0.00024138812,0.00019300457,0.0001896182,0.00026618713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010271533,0.0001570168,0.00023316388,0.000090202535,0.00005255546,0.00001003574,0.00016926542,0.00012061568,0.000028040127],"category_scores_gemma":[0.0001334746,0.0001359121,0.00012396235,0.00010322468,0.00018654451,0.000010387238,0.00004194822,0.000112017784,0.0000070332103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004113007,0.000058711124,0.0188848,0.000008384253,0.00012521031,0.000014561086,0.00015697257,0.00051545294,0.97616595,0.00009162279,0.003337042,0.00060015527],"study_design_scores_gemma":[0.0005489071,0.000110421235,0.12494075,0.000006338872,0.000026229842,0.001554208,0.00003536714,0.000030556424,0.8610897,0.00036637596,0.011155695,0.00013542178],"about_ca_topic_score_codex":0.0000012191321,"about_ca_topic_score_gemma":6.807505e-7,"teacher_disagreement_score":0.11507623,"about_ca_system_score_codex":0.000013733491,"about_ca_system_score_gemma":0.00009480844,"threshold_uncertainty_score":0.55423343},"labels":[],"label_agreement":null},{"id":"W4235666967","doi":"10.1007/978-1-4939-1363-3_1","title":"Yeast Transformation by the LiAc/SS Carrier DNA/PEG Method","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":257,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transformation (genetics); Yeast; Protocol (science); Transformation efficiency; DNA; Computational biology; Computer science; Microtiter plate; Biology; Molecular biology; Genetics; Gene; Medicine; Agrobacterium","score_opus":0.008353399979741575,"score_gpt":0.39979978677887906,"score_spread":0.3914463867991375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4235666967","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02007344,0.0010335583,0.9761132,0.00030995713,0.000359251,0.00020073554,0.000018426597,0.000014860315,0.0018765767],"genre_scores_gemma":[0.23109438,0.00013069053,0.7662315,0.0014310529,0.00020454187,0.00013336496,0.00021492626,0.00006261668,0.00049697724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978835,0.0010786918,0.00028403374,0.0003563033,0.000066494285,0.00033099222],"domain_scores_gemma":[0.99934405,0.00006098058,0.00005142655,0.00044618783,0.000036043384,0.00006128525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016721968,0.00019463919,0.00021105385,0.000056940196,0.000053881005,0.000015151065,0.0003023103,0.00026965782,0.000016337226],"category_scores_gemma":[0.00026403353,0.00015303756,0.00011549477,0.00014665558,0.000082785664,0.0000021299338,0.00007385815,0.00017947801,0.0000033270292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000144844,0.00001274613,0.000086951986,0.000009405696,0.000025800931,4.4793842e-7,0.000092290735,0.0004928985,0.94926906,0.0010562394,0.0002443033,0.048695393],"study_design_scores_gemma":[0.00033202392,0.00011804702,0.00010748745,0.0000039911947,0.000015629526,0.00001727024,0.00004941742,0.0016521502,0.81619954,0.0008733897,0.18045558,0.00017550359],"about_ca_topic_score_codex":0.00003044558,"about_ca_topic_score_gemma":0.000017149692,"teacher_disagreement_score":0.21102095,"about_ca_system_score_codex":0.000012005206,"about_ca_system_score_gemma":0.000019728122,"threshold_uncertainty_score":0.62406904},"labels":[],"label_agreement":null},{"id":"W4236010103","doi":"10.3410/f.1162797.628175","title":"Faculty Opinions recommendation of iPS cells produce viable mice through tetraploid complementation.","year":2009,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Complementation; Biology; Computational biology; Genetics; Gene; Phenotype","score_opus":0.024305663069963953,"score_gpt":0.3775825260670202,"score_spread":0.35327686299705624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236010103","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000002576027,0.0018555262,0.0005242789,0.046713375,0.00071738946,0.0011419223,0.9489736,0.000017291604,0.000054020667],"genre_scores_gemma":[0.000034696244,0.00076977024,0.0030893683,0.0029533685,0.0004214846,0.00011522853,0.99187803,0.000025729476,0.00071229675],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99683475,0.00020692701,0.0011922722,0.0006744347,0.0007661437,0.00032546456],"domain_scores_gemma":[0.99496615,0.000033931392,0.00083434,0.0012065704,0.0028082614,0.00015076196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006761985,0.00044823167,0.00059306,0.00013456315,0.00016153257,0.000070508504,0.0011048616,0.00048434103,0.00016936426],"category_scores_gemma":[0.0013686087,0.00033214965,0.00042032544,0.0009395608,0.00015826109,0.00003279481,0.00029923365,0.00050065946,0.000017965569],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010124185,0.0002611977,0.0000022659474,0.00323246,0.00011340811,7.719154e-8,0.00005503426,0.0000028016618,0.0006505935,0.000026706355,0.99490285,0.0007424923],"study_design_scores_gemma":[0.0004951821,0.00019837526,0.00033116632,0.002343084,0.00012992237,0.00001691143,0.000032646272,0.0000042129636,0.0067683435,0.000010978128,0.98934376,0.00032543825],"about_ca_topic_score_codex":0.0000324581,"about_ca_topic_score_gemma":0.000007703529,"teacher_disagreement_score":0.043760005,"about_ca_system_score_codex":0.00004241545,"about_ca_system_score_gemma":0.00027793375,"threshold_uncertainty_score":0.99991304},"labels":[],"label_agreement":null},{"id":"W4237139671","doi":"10.21203/rs.2.10333/v1","title":"Sockeye salmon demonstrate robust yet distinct transcriptomic kidney responses to rhabdovirus (IHNV) exposure and infection","year":2019,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Fisheries and Oceans Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Génome Québec","keywords":"Biology; Transcriptome; Fish <Actinopterygii>; Zoology; Fishery; Virology; Genetics; Gene; Gene expression","score_opus":0.034647023964156004,"score_gpt":0.37218256647244535,"score_spread":0.3375355425082893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4237139671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874753,0.0024108733,0.0072259344,0.00036339278,0.00046534304,0.001073259,0.00037996794,0.00004439283,0.00056158635],"genre_scores_gemma":[0.99587804,0.0013325483,0.00048476653,0.000054606833,0.00034739537,0.00016134938,0.00039546823,0.000075235104,0.0012705763],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9973763,0.0003478987,0.00030532927,0.000911697,0.00043305516,0.0006257097],"domain_scores_gemma":[0.99841994,0.00006974223,0.000047788046,0.00076733844,0.00025047653,0.00044472184],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00084289623,0.00035262012,0.00031625014,0.00029517218,0.00016458366,0.0001691036,0.00028400478,0.0005795398,0.000035564142],"category_scores_gemma":[0.0006328925,0.00036192706,0.00015729734,0.00018232802,0.00010860806,0.0000047310386,0.0006231041,0.00082702533,0.000038361763],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014591714,0.0001806589,0.11236265,0.0030159345,0.0002755248,0.000051788684,0.0005337995,0.007960686,0.8456138,0.000027090042,0.016062258,0.012456625],"study_design_scores_gemma":[0.0023324685,0.0034801234,0.48000762,0.0020976348,0.00013712124,0.000113579,0.00044909667,0.0020446028,0.43618765,0.00031811435,0.070605986,0.0022259925],"about_ca_topic_score_codex":0.00030339984,"about_ca_topic_score_gemma":0.0002409232,"teacher_disagreement_score":0.40942615,"about_ca_system_score_codex":0.000070812945,"about_ca_system_score_gemma":0.00038035907,"threshold_uncertainty_score":0.9998833},"labels":[],"label_agreement":null},{"id":"W4238051829","doi":"10.22215/etd/2008-06507","title":"Giving life to the labour process: transgenic biotechnology and the meaning of nature","year":2008,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Heritage; Library and Archives Canada","funders":"","keywords":"Meaning (existential); Meaning of life; Humanities; Sociology; Political science; Biotechnology; Philosophy; Biology; Epistemology","score_opus":0.0028980915787127862,"score_gpt":0.26625193817537296,"score_spread":0.26335384659666017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238051829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838147,0.011429469,0.0015619881,0.0011443974,0.00021761193,0.00037970656,0.000016884087,0.000017327335,0.0014179215],"genre_scores_gemma":[0.99459034,0.0023284412,0.00021502936,0.00025772452,0.00011787697,0.000032445325,0.00005974158,0.00002493897,0.0023734837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932164,0.000018631252,0.00017793306,0.00023850097,0.00009950043,0.00014380831],"domain_scores_gemma":[0.9995563,0.000016695316,0.0000589959,0.00026699886,0.000068407375,0.0000326252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116546515,0.00016122291,0.00018276012,0.000044746746,0.000080128,0.00000943329,0.0002679215,0.000519167,0.000009016877],"category_scores_gemma":[0.00016643877,0.00009248182,0.00007352194,0.000120086974,0.000051847972,7.6823983e-7,0.000027476952,0.00029978558,6.422459e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007068198,0.000045795518,0.00016341386,0.0010713834,0.0006943549,0.0000021930932,0.0077633006,0.0023505064,0.9675667,0.006477497,0.0024226443,0.010735385],"study_design_scores_gemma":[0.00058441283,0.00010469941,0.00097322866,0.00006469842,0.00006112008,0.000016941516,0.0036041231,0.00009014811,0.96795464,0.00008476999,0.026203144,0.0002580563],"about_ca_topic_score_codex":0.000019264335,"about_ca_topic_score_gemma":0.00037548612,"teacher_disagreement_score":0.023780499,"about_ca_system_score_codex":0.0000020418026,"about_ca_system_score_gemma":0.0000613946,"threshold_uncertainty_score":0.40042913},"labels":[],"label_agreement":null},{"id":"W4238889116","doi":"10.26434/chemrxiv.11882142","title":"Combining Rational Design and Continuous Evolution on Minimalist Proteins That Target DNA","year":2020,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Leucine zipper; Zipper; DNA; Rational design; Transcription factor; Transcription (linguistics); Biology; Computational biology; Enhancer; Cell biology; Genetics; Gene; Computer science","score_opus":0.020261578206023395,"score_gpt":0.2691853118191317,"score_spread":0.2489237336131083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238889116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5127958,0.0020474563,0.48226598,0.0006471678,0.00038497074,0.000916066,0.000017799386,0.000058298,0.00086644583],"genre_scores_gemma":[0.98787796,0.000059128546,0.010953389,0.00012269082,0.00033325911,0.00011012464,0.0003368828,0.000035657627,0.00017092164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897504,0.000037005717,0.00016342776,0.0005149822,0.00013011995,0.00017944779],"domain_scores_gemma":[0.9995016,0.00001549329,0.00008474546,0.00025654427,0.00004543576,0.00009618448],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013116414,0.00024361777,0.00021254513,0.00003092204,0.000057774112,0.00004957129,0.00014303718,0.00027780456,0.000011864547],"category_scores_gemma":[0.000087839835,0.00026161975,0.00007769885,0.000028751558,0.000054614025,0.0000015259297,0.00024050358,0.00022610939,0.0000049756354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001160633,0.000044687848,0.0007283921,0.00014748458,0.000091774506,0.0000067923697,0.00009360439,0.003664406,0.9916904,0.0002793072,0.00294289,0.0001941924],"study_design_scores_gemma":[0.00059309,0.0002832893,0.0036182932,0.00008671032,0.000036097197,0.000010344344,0.000046881036,0.003991177,0.98533916,0.00091086945,0.0046189115,0.0004651836],"about_ca_topic_score_codex":0.000004840183,"about_ca_topic_score_gemma":9.214674e-7,"teacher_disagreement_score":0.47508213,"about_ca_system_score_codex":0.000020978927,"about_ca_system_score_gemma":0.000089236644,"threshold_uncertainty_score":0.9999836},"labels":[],"label_agreement":null},{"id":"W4239031759","doi":"10.1007/978-1-4939-7131-2_100309","title":"Edit Networks","year":2018,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Computer science","score_opus":0.006233401214520246,"score_gpt":0.2555464406995019,"score_spread":0.24931303948498165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239031759","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000063959305,0.002184941,0.052297823,0.000019566201,0.0008317027,0.00009748271,0.000008136174,0.000025296698,0.9444711],"genre_scores_gemma":[0.0043934104,0.000708043,0.0006248146,0.00020704883,0.005120552,0.0000034639224,0.00020992993,0.00006503906,0.9886677],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993545,0.0000017416824,0.00012843404,0.00028489437,0.00007288971,0.00015757389],"domain_scores_gemma":[0.99948883,0.0000027560184,0.00003251629,0.0003616023,0.00004835293,0.000065925655],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000043541673,0.00020029262,0.00012712264,0.000023516714,0.000023910901,0.000012356653,0.00013475442,0.00042173755,0.0016802258],"category_scores_gemma":[0.000005128718,0.00019228652,0.00010852308,0.000005106256,0.00004601558,2.9182155e-7,0.000108954446,0.00010122726,0.00014608886],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027148946,0.000008705816,0.000008054934,0.000029973698,0.00024000998,0.0000085365145,0.000013123761,0.0006582015,0.0069429106,0.00486536,0.9794736,0.007724396],"study_design_scores_gemma":[0.0000854922,0.000113886585,0.000004807158,0.000017066906,0.000022120277,0.00001019774,0.0000016295514,0.00013497531,0.0035689734,0.0002860074,0.9954913,0.00026350305],"about_ca_topic_score_codex":0.0000010744045,"about_ca_topic_score_gemma":0.000014751364,"teacher_disagreement_score":0.05167301,"about_ca_system_score_codex":0.0000050624635,"about_ca_system_score_gemma":0.000019521483,"threshold_uncertainty_score":0.99923235},"labels":[],"label_agreement":null},{"id":"W4240101819","doi":"10.1002/047001153x.g202310","title":"Fingerprint mapping","year":2005,"lang":"en","type":"other","venue":"Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Fingerprint (computing); Genome; Computational biology; Biology; Genomics; clone (Java method); Restriction enzyme; Genetics; Caenorhabditis elegans; Computer science; Artificial intelligence; Gene","score_opus":0.0051393916561155335,"score_gpt":0.2357408803638426,"score_spread":0.23060148870772706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240101819","genre_codex":"other","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05361046,0.051578015,0.13028918,0.00023950533,0.0023174048,0.004221889,0.0010302854,0.00019136022,0.7565219],"genre_scores_gemma":[0.0023507546,0.1664808,0.63780487,0.0002602057,0.003147725,0.00007321809,0.0005284764,0.0008737012,0.18848026],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99826986,0.000016184838,0.000754048,0.0003775532,0.00017377819,0.00040856237],"domain_scores_gemma":[0.99862146,0.000008134062,0.00048460974,0.00065905397,0.000059688067,0.0001670304],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020201519,0.00048098597,0.0004941314,0.00024117732,0.00004798576,0.00003571352,0.0003663592,0.0005701554,0.00009858022],"category_scores_gemma":[0.00004535515,0.00051008107,0.00014763123,0.000069764545,0.00016244821,0.0000031353127,0.00043633836,0.00020900767,0.000022694505],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013746369,0.00036106858,0.002895966,0.0056435154,0.0016628243,0.000008665109,0.0034965712,0.0031183443,0.09532209,0.00022840845,0.36469784,0.5224272],"study_design_scores_gemma":[0.00050172635,0.0001584997,0.0002197506,0.00012954905,0.000053392454,0.000016040276,0.00015602172,0.0013383364,0.015014124,0.000025976808,0.9817029,0.000683673],"about_ca_topic_score_codex":0.000029137505,"about_ca_topic_score_gemma":0.0000656538,"teacher_disagreement_score":0.61700505,"about_ca_system_score_codex":0.000025414127,"about_ca_system_score_gemma":0.0001563633,"threshold_uncertainty_score":0.99973506},"labels":[],"label_agreement":null},{"id":"W4240274708","doi":"10.1093/nar/gky512","title":"Optimized knock-in of point mutations in zebrafish using CRISPR/Cas9","year":2018,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Appili Therapeutics (Canada); McMaster University; Dalhousie University","funders":"","keywords":"CRISPR; Biology; Cas9; Zebrafish; Genetics; Gene knockin; Point mutation; Computational biology; Palindrome; Genome editing; Polymerase chain reaction; Mutation; Gene","score_opus":0.03848736674112608,"score_gpt":0.40325628251768936,"score_spread":0.3647689157765633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240274708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99066293,0.00023219932,0.0063243373,0.000106264546,0.000061074206,0.00020203827,0.000006647078,0.0000055374944,0.0023989654],"genre_scores_gemma":[0.99058986,0.000042188673,0.009054773,0.000018571258,0.00011800953,0.000012331438,0.000011954736,0.000022832353,0.00012950339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987771,0.00010817815,0.0002500458,0.0002688954,0.00022231917,0.0003734695],"domain_scores_gemma":[0.9993805,0.000030817602,0.000022638576,0.0003157632,0.00018522632,0.00006504825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070552627,0.00009075193,0.00014583535,0.00026216175,0.000049363214,0.000016140659,0.00021200905,0.00012870558,0.00010719306],"category_scores_gemma":[0.00029019648,0.00009623173,0.000046170087,0.00042503278,0.00019557806,0.0000048453603,0.00017288548,0.00018888287,0.000011579727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011165412,0.00009012783,0.0032974826,0.000030922638,0.000013649283,0.000008576483,0.0004152116,0.003205878,0.9910789,0.000052971165,0.00040817683,0.0012864398],"study_design_scores_gemma":[0.0019133462,0.0004522899,0.014906285,0.00008573558,0.000005587871,0.000015878724,0.0009648557,0.027435591,0.95111907,0.00027153082,0.0025978643,0.00023195492],"about_ca_topic_score_codex":0.00019828997,"about_ca_topic_score_gemma":0.0001256856,"teacher_disagreement_score":0.03995983,"about_ca_system_score_codex":0.000036844,"about_ca_system_score_gemma":0.00009637074,"threshold_uncertainty_score":0.3924216},"labels":[],"label_agreement":null},{"id":"W4240581071","doi":"10.1016/j.tibtech.2015.09.011","title":"Bioart","year":2015,"lang":"en","type":"review","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Parks Canada","keywords":"Openness to experience; Engineering ethics; Sociology; Politics; Criticism; Emerging technologies; Epistemology; Political science; Psychology; Computer science; Philosophy","score_opus":0.03798165930302386,"score_gpt":0.4024181625819442,"score_spread":0.3644365032789203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240581071","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000015358795,0.9977805,0.00016034476,0.000050132832,0.00028274205,0.00010003378,0.000030165103,0.000054073458,0.0015266325],"genre_scores_gemma":[0.000040871488,0.9970389,0.00053424115,0.000011115899,0.00015113193,0.000049654973,0.00040293537,0.000053134896,0.0017179892],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99871343,0.00003544964,0.00034035812,0.0005006763,0.00007067166,0.00033943483],"domain_scores_gemma":[0.99916536,0.0000047645294,0.00007987039,0.0006821006,0.000014702336,0.000053184554],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00015440182,0.00032634498,0.00076152344,0.00063225615,0.000013014907,0.0000072204066,0.00042545452,0.0015440795,0.00002671675],"category_scores_gemma":[0.00003061382,0.00029808132,0.00019298728,0.000538676,0.000108089574,6.3588607e-7,0.0002502124,0.0003561932,0.00004949824],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000017764661,0.000018926807,0.0000014715262,0.0002982282,0.000031892054,0.000010934495,0.0000021428505,0.0000024465332,0.000086975684,0.00010521928,0.0033707584,0.99606925],"study_design_scores_gemma":[0.00014481855,0.0001129561,0.0000011446376,0.00027764012,0.000052959094,0.000088039225,0.0000038168628,0.000002068543,0.00048996584,0.00001814143,0.9985088,0.00029965618],"about_ca_topic_score_codex":0.0000074238037,"about_ca_topic_score_gemma":0.00005291115,"teacher_disagreement_score":0.99576956,"about_ca_system_score_codex":0.000033007305,"about_ca_system_score_gemma":0.00007143705,"threshold_uncertainty_score":0.99994713},"labels":[],"label_agreement":null},{"id":"W4240581202","doi":"10.3410/f.726182989.793521159","title":"Faculty Opinions recommendation of Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.","year":2016,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Genome editing; Nanoparticle; Computational biology; Genome; Computer science; Nanotechnology; Chemistry; Biology; Gene; Biochemistry; Materials science","score_opus":0.023252585397232923,"score_gpt":0.3480451767294876,"score_spread":0.3247925913322547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240581202","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015881938,0.0017668128,0.00049197103,0.011427889,0.00057697686,0.00094300427,0.984614,0.000009990332,0.000010516148],"genre_scores_gemma":[0.00051301497,0.00028284814,0.0012231444,0.0003053384,0.00043766884,0.00007495522,0.997029,0.000024268138,0.00010974628],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99720174,0.00017180563,0.0011685343,0.0005160266,0.0006457656,0.00029611107],"domain_scores_gemma":[0.9949349,0.000027627302,0.0010113673,0.0010536552,0.0028075455,0.00016487349],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081329036,0.00034560397,0.00055501884,0.00019481716,0.00011170762,0.00003204375,0.00080981536,0.00045256712,0.00008073744],"category_scores_gemma":[0.0020038334,0.00022959866,0.00041534685,0.0007368791,0.00024393154,0.000015532718,0.00046616554,0.0002861635,0.000004327403],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011387439,0.00021081312,0.000004284491,0.0041024857,0.00011072388,7.166012e-8,0.000037006175,0.000011412206,0.0113285305,0.000012935275,0.9832874,0.0008829495],"study_design_scores_gemma":[0.0004150747,0.00013168917,0.00024492946,0.0050564813,0.00010947344,0.000015918418,0.000020446776,0.000036860998,0.016529378,0.0000013017127,0.97721046,0.00022797217],"about_ca_topic_score_codex":0.000029164701,"about_ca_topic_score_gemma":0.0000022946047,"teacher_disagreement_score":0.012414996,"about_ca_system_score_codex":0.000047483758,"about_ca_system_score_gemma":0.00035596793,"threshold_uncertainty_score":0.93627614},"labels":[],"label_agreement":null},{"id":"W4241277615","doi":"10.1007/978-3-319-78259-1_5","title":"Conclusions and Perspectives","year":2018,"lang":"en","type":"article","venue":"Experientia supplementum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Epistemology; Philosophy","score_opus":0.007700480073821244,"score_gpt":0.312499560545319,"score_spread":0.3047990804714978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4241277615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809033,0.0016339519,0.014364043,0.00027080905,0.00029157178,0.00012105741,0.0000228639,0.000016913178,0.0023754714],"genre_scores_gemma":[0.99709165,0.00008533449,0.0015488991,0.00006412266,0.00034476566,0.000018987883,0.00004776442,0.000011775893,0.00078671024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994842,0.000009542603,0.00007653164,0.0002174315,0.000057111403,0.00015522589],"domain_scores_gemma":[0.9997182,0.000001962844,0.000012554388,0.00016855159,0.00003979953,0.0000589275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038863625,0.00007982718,0.000053340154,0.000021179667,0.00011303719,0.00001749636,0.00006185696,0.000032138327,0.00070625043],"category_scores_gemma":[0.000014149112,0.00007938335,0.000024661571,0.000032738,0.00010790397,0.0000017956164,0.00015893523,0.000022844317,0.000009162509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021471387,0.00003826904,0.0023356914,0.000004564275,0.000041092186,0.0000013836865,0.0053341226,0.0000010742868,0.96159065,0.0015551387,0.028175488,0.0009010363],"study_design_scores_gemma":[0.00035651316,0.0002664937,0.0013424284,0.0000028956165,0.0000066000716,0.000009562952,0.0066505983,0.00004845606,0.5075665,0.000028627663,0.48358503,0.0001362775],"about_ca_topic_score_codex":0.000007576827,"about_ca_topic_score_gemma":0.00001880643,"teacher_disagreement_score":0.45540956,"about_ca_system_score_codex":0.0000037160285,"about_ca_system_score_gemma":0.000010720402,"threshold_uncertainty_score":0.77329475},"labels":[],"label_agreement":null},{"id":"W4242117580","doi":"10.3410/f.718013253.793477320","title":"Faculty Opinions recommendation of Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation.","year":2013,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"DNA damage; Function (biology); Incident response; Chemistry; DNA; Computer science; Computer security; Cell biology; Biology; Biochemistry","score_opus":0.017020248652231482,"score_gpt":0.34245972941750763,"score_spread":0.3254394807652761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242117580","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006458742,0.0016602173,0.0001634802,0.06290508,0.00034647592,0.000974667,0.9338576,0.000007315612,0.00002055912],"genre_scores_gemma":[0.00035480125,0.0004987762,0.00014611668,0.0023594368,0.00012507089,0.00016268712,0.9959584,0.000019170871,0.0003755666],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967943,0.000568919,0.0011831332,0.0004565202,0.0007670154,0.00023011409],"domain_scores_gemma":[0.99559146,0.00012963814,0.00086142356,0.0012062561,0.0021047613,0.00010646968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016151136,0.00034620173,0.00050338753,0.00020925388,0.00008293682,0.000045489618,0.0010383708,0.0006225652,0.00022691542],"category_scores_gemma":[0.004357213,0.00021882927,0.00032942902,0.001139761,0.00019076762,0.00002875964,0.00023861218,0.00049896137,0.000012720453],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004691142,0.00019214141,0.0000070666547,0.001548607,0.00007889,4.4472824e-8,0.00009767689,6.952776e-7,0.0009594264,0.00001314596,0.9965174,0.00053798297],"study_design_scores_gemma":[0.0005415587,0.00020907566,0.004248801,0.0016116044,0.0000837623,0.000006067556,0.00005256842,0.000017368071,0.0008839964,0.000005409612,0.99213564,0.00020416708],"about_ca_topic_score_codex":0.000046961555,"about_ca_topic_score_gemma":0.0000071519394,"teacher_disagreement_score":0.062100757,"about_ca_system_score_codex":0.000030818566,"about_ca_system_score_gemma":0.00023140812,"threshold_uncertainty_score":0.89235985},"labels":[],"label_agreement":null},{"id":"W4242148195","doi":"10.3410/f.727521283.793533622","title":"Faculty Opinions recommendation of Marker-free coselection for CRISPR-driven genome editing in human cells.","year":2017,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Genome; Computer science; Biology; World Wide Web; Genetics; Gene","score_opus":0.021887416211127542,"score_gpt":0.3831248140837686,"score_spread":0.36123739787264103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242148195","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000004917047,0.00087025255,0.00077691086,0.018822195,0.00091029966,0.0013013387,0.9772677,0.00001118446,0.00003519861],"genre_scores_gemma":[0.0000804303,0.00031818854,0.0011707003,0.00051169284,0.00071489596,0.00029112358,0.99633753,0.000030268075,0.0005451777],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974002,0.00015537857,0.001046548,0.00058754196,0.00049152115,0.0003187784],"domain_scores_gemma":[0.99505955,0.000035490673,0.001008339,0.0014757912,0.0022795752,0.00014126387],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009501958,0.00038043654,0.00058695284,0.00022289476,0.00023730467,0.0000844689,0.0014642384,0.0006654,0.000050837873],"category_scores_gemma":[0.0032697725,0.00030106195,0.00044455097,0.00040452753,0.00015567648,0.00002547409,0.0004798737,0.00050514675,0.0000032855344],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012106738,0.0001426779,0.000006958318,0.004246104,0.000079332385,8.183414e-8,0.000024719131,0.0000028549537,0.00086521014,0.000014877375,0.99399763,0.0006074668],"study_design_scores_gemma":[0.0007780903,0.00017856258,0.0011520315,0.0027664183,0.000089907524,0.000009619494,0.000014166658,0.00002350779,0.0010833521,0.000011742036,0.9936166,0.00027602163],"about_ca_topic_score_codex":0.00004016121,"about_ca_topic_score_gemma":0.000040728974,"teacher_disagreement_score":0.01906982,"about_ca_system_score_codex":0.00006016871,"about_ca_system_score_gemma":0.0002035229,"threshold_uncertainty_score":0.99994415},"labels":[],"label_agreement":null},{"id":"W4242188613","doi":"10.1515/iupac.83.0426","title":"Nuclease Assay","year":2016,"lang":"en","type":"dataset","venue":"IUPAC Standards Online","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Glossary; Context (archaeology); Computer science; Process (computing); Field (mathematics); Multidisciplinary approach; Data science; Management science; Engineering; Biology; Sociology; Linguistics; Mathematics","score_opus":0.006643879428522755,"score_gpt":0.3952262344792684,"score_spread":0.3885823550507457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242188613","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026110292,0.0017790734,0.0028660586,0.00015809876,0.00063146796,0.00014770233,0.9940683,0.000021679192,0.00006648319],"genre_scores_gemma":[0.00023025705,0.0015029599,0.00009003825,0.00023361457,0.0017180772,0.000009956879,0.99540275,0.000052341296,0.0007599828],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99842715,0.000045120658,0.0002727676,0.0004955418,0.00040133053,0.0003580572],"domain_scores_gemma":[0.9986618,0.000013706821,0.00009219654,0.00086511654,0.00019368257,0.00017348131],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030511463,0.00035635594,0.00030005773,0.00007626152,0.00005503327,0.00003007207,0.00035491344,0.0004366558,0.0008444708],"category_scores_gemma":[0.00036741505,0.0002932671,0.00017589056,0.00005823519,0.00006990593,0.0000014975827,0.00021321069,0.00020098139,0.000003334907],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006891214,0.00006437806,0.0000039432152,0.00006331384,0.000089883484,0.000020247255,0.0000013698505,0.00001067248,0.0040870514,0.0000011237166,0.9924405,0.003148609],"study_design_scores_gemma":[0.0005452816,0.00020006367,0.000016766087,0.000090462265,0.00006159688,0.000019182762,0.0000056989506,0.0000035475327,0.0029384033,0.000011080771,0.9956993,0.0004086231],"about_ca_topic_score_codex":0.00001995366,"about_ca_topic_score_gemma":0.00018261682,"teacher_disagreement_score":0.0032587978,"about_ca_system_score_codex":0.000054509128,"about_ca_system_score_gemma":0.00029427066,"threshold_uncertainty_score":0.99995196},"labels":[],"label_agreement":null},{"id":"W4242403585","doi":"10.3410/f.737316694.793572169","title":"Faculty Opinions recommendation of Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Neurological Disorders and Stroke; Japan Society for the Promotion of Science; National Institute of Child Health and Human Development; Natural Sciences and Engineering Research Council of Canada; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of British Columbia; National Natural Science Foundation of China; National Institute of Mental Health; Fudan University; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Max-Planck-Gesellschaft; Deutsche Forschungsgemeinschaft; Simons Foundation Autism Research Initiative; Howard Hughes Medical Institute; Ministry of Education, Culture, Sports, Science and Technology; Canadian Institutes of Health Research; National Science Foundation","keywords":"Germline; Recombinase; Biology; Genetics; Recombination; Cre recombinase; Locus (genetics); Homologous recombination; FLP-FRT recombination; Gene; Genetic recombination; Transgene","score_opus":0.015791814710234456,"score_gpt":0.31409250136655464,"score_spread":0.2983006866563202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242403585","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014498467,0.0033867662,0.0009620424,0.005644979,0.00029386475,0.00080543716,0.9887398,0.000016916882,0.0000052263767],"genre_scores_gemma":[0.0010591813,0.0014624781,0.003591002,0.00019061676,0.0001860847,0.00005255601,0.993374,0.000026219126,0.000057891142],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973521,0.00017781397,0.001123257,0.0005603928,0.00057884655,0.00020759499],"domain_scores_gemma":[0.9952816,0.00004567769,0.0011293987,0.0006484134,0.0027351899,0.0001597598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054524164,0.0003831024,0.0006158053,0.00015150095,0.00011348152,0.00004726682,0.0006084651,0.00042309548,0.00001883539],"category_scores_gemma":[0.001395181,0.00026216256,0.00022739956,0.0006639713,0.00015864539,0.000032891607,0.0003290529,0.00040687743,0.0000011880475],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017904591,0.000078984,0.00003693584,0.018021151,0.000114401504,1.7882026e-7,0.00015629869,0.00001700556,0.0013254997,0.000015533333,0.97971874,0.00049736106],"study_design_scores_gemma":[0.00046431136,0.00022445476,0.0017318431,0.0077940025,0.0001448603,0.000022035161,0.00009094476,0.000054119977,0.003071137,7.471722e-7,0.9861285,0.00027303913],"about_ca_topic_score_codex":0.000016694574,"about_ca_topic_score_gemma":0.0000012517854,"teacher_disagreement_score":0.010227148,"about_ca_system_score_codex":0.000045093213,"about_ca_system_score_gemma":0.00017253429,"threshold_uncertainty_score":0.9999831},"labels":[],"label_agreement":null},{"id":"W4242775739","doi":"10.1007/978-0-387-30440-3_79","title":"Complex Gene Regulatory Networks – from Structure to Biological Observables: Cell Fate Determination","year":2009,"lang":"en","type":"book-chapter","venue":"Encyclopedia of Complexity and Systems Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Observable; Gene regulatory network; Computational biology; Cell fate determination; Gene; Biology; Genetics; Gene expression; Physics; Transcription factor","score_opus":0.03069565107047595,"score_gpt":0.27123457664706485,"score_spread":0.2405389255765889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242775739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.801096,0.012306321,0.049941283,0.00006324954,0.0018593395,0.0015889381,0.0008728826,0.00006916495,0.13220277],"genre_scores_gemma":[0.9820065,0.0010617288,0.006193629,0.00008535925,0.0006039917,0.000005051099,0.00030223271,0.000024248293,0.009717262],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983053,0.000025751006,0.00041808895,0.0006593492,0.0003052718,0.0002862006],"domain_scores_gemma":[0.9989334,0.00002365627,0.00019813328,0.00049478805,0.00015253718,0.00019751712],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024472864,0.00030652268,0.00041540075,0.000092025686,0.00014112549,0.00004776487,0.00045875603,0.0003202558,0.000021936916],"category_scores_gemma":[0.000027297547,0.00028269505,0.00007202259,0.00006390003,0.00043039524,0.000007356771,0.00021789329,0.00014490544,0.000001974137],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010919188,0.000050168615,0.00066925277,0.00018798199,0.00005020218,0.000016191225,0.00039538412,0.010154456,0.9504624,0.00853621,0.0016946495,0.027673882],"study_design_scores_gemma":[0.002348299,0.0035183132,0.21607834,0.0012429701,0.00022528096,0.00016268987,0.00029022022,0.041677833,0.07952191,0.015373887,0.6339195,0.005640786],"about_ca_topic_score_codex":0.000040874518,"about_ca_topic_score_gemma":0.00003442731,"teacher_disagreement_score":0.8709405,"about_ca_system_score_codex":0.000023403289,"about_ca_system_score_gemma":0.000071970455,"threshold_uncertainty_score":0.9999625},"labels":[],"label_agreement":null},{"id":"W4242957513","doi":"10.1128/9781555817954.ch20","title":"Transposon Tn<i>10</i>","year":2007,"lang":"he","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Transposable element; Transposition (logic); DNA; Mutant; Resolution (logic); Stereoselectivity; Genetics; Stereochemistry; Inverted repeat; Chemistry; Biology; Molecular biology; Biophysics; Gene; Biochemistry; Genome","score_opus":0.005743180986279439,"score_gpt":0.2895247898146438,"score_spread":0.28378160882836434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242957513","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011552066,0.01317575,0.057521492,0.00011150514,0.0007490173,0.00031737835,0.00005432052,0.000047439735,0.9268679],"genre_scores_gemma":[0.043403387,0.0019059036,0.0020438242,0.00029662595,0.0013310601,0.000008519944,0.00030926365,0.0003468919,0.9503545],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982217,0.000022369017,0.00033090546,0.0006662836,0.00019303092,0.0005656999],"domain_scores_gemma":[0.99903077,0.000009920373,0.000067583744,0.00063732953,0.00004845259,0.00020595631],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00015713791,0.00050978945,0.00034182207,0.00015379503,0.000041747244,0.000027920525,0.0003099107,0.0010151527,0.04207839],"category_scores_gemma":[0.000011346184,0.00050021685,0.00028456,0.00013168664,0.00011682819,6.7661216e-7,0.000057174388,0.00020512588,0.0024367918],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015973792,0.00027630635,0.00032308497,0.0007172139,0.0008394432,0.00006421876,0.000113959926,0.00031896553,0.24806646,0.00070322613,0.692462,0.055955324],"study_design_scores_gemma":[0.00044500045,0.00019285631,0.000089509434,0.00006014038,0.000069047805,0.000010595593,0.00004412883,0.000025312442,0.15935433,0.000004404834,0.8391548,0.0005499036],"about_ca_topic_score_codex":0.000035820194,"about_ca_topic_score_gemma":0.00015269306,"teacher_disagreement_score":0.14669271,"about_ca_system_score_codex":0.000016025167,"about_ca_system_score_gemma":0.00007077563,"threshold_uncertainty_score":0.99974495},"labels":[],"label_agreement":null},{"id":"W4242987318","doi":"10.1128/9781555819217.ch54","title":"An Unexplored Diversity of Reverse Transcriptases in Bacteria","year":2015,"lang":"en","type":"book-chapter","venue":"ASM Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Retrotransposon; Reverse transcriptase; Biology; Telomerase; Rous sarcoma virus; Pseudogene; Long terminal repeat; Genetics; Telomerase reverse transcriptase; Integrase; Virology; Genome; DNA; Virus; Gene; RNA; Transposable element","score_opus":0.046406691723918536,"score_gpt":0.2905299060529758,"score_spread":0.24412321432905726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242987318","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.119603194,0.00632828,0.001381134,0.000014748915,0.0010859616,0.0011071338,0.0011096041,0.000070068854,0.8692999],"genre_scores_gemma":[0.8000524,0.0003774702,0.00077412545,0.00004187401,0.00026974914,0.000014272087,0.00053612416,0.00009567401,0.19783829],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992282,0.000015632333,0.00020174414,0.00029039936,0.00012259891,0.0001414741],"domain_scores_gemma":[0.9993566,0.0000031635673,0.00006824525,0.00042465708,0.00006123532,0.00008608997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088847875,0.00020499897,0.00024363409,0.000048756505,0.000019491461,0.0000062617924,0.00023730284,0.0002896131,0.000017102213],"category_scores_gemma":[0.0000063106872,0.00022513789,0.00009129188,0.000002674424,0.00006449452,0.0000021039823,0.00015393375,0.00011070927,0.0000010657999],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056051795,0.00008303417,0.00008694684,0.0003579654,0.00031986565,0.00006557577,0.0015122578,0.00047184384,0.9740123,0.005916009,0.0075075836,0.009106071],"study_design_scores_gemma":[0.0013436292,0.0005328933,0.00019050423,0.00018111615,0.0001475406,0.000009556584,0.000049420454,0.000026056066,0.27503392,0.0007806737,0.7209928,0.0007119003],"about_ca_topic_score_codex":0.0001727895,"about_ca_topic_score_gemma":0.00011324735,"teacher_disagreement_score":0.7134852,"about_ca_system_score_codex":0.000010207175,"about_ca_system_score_gemma":0.000036127993,"threshold_uncertainty_score":0.91808563},"labels":[],"label_agreement":null},{"id":"W4243084792","doi":"10.32920/ryerson.14643987.v1","title":"In defense of traditional knowledge: the case of Bt brinjal and challenges to the international intellectual property agenda","year":2021,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University; York University","funders":"","keywords":"Lawsuit; Intellectual property; Tamil; Harmonization; Traditional knowledge; Agriculture; Treaty; Political science; Globalization; Law; International trade; Business; Geography; Biology","score_opus":0.05539790097905002,"score_gpt":0.309563482783608,"score_spread":0.254165581804558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243084792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97767735,0.012519504,0.0023843877,0.0024659834,0.00045272734,0.0002981942,0.00006559578,0.0000030442638,0.0041332357],"genre_scores_gemma":[0.99662876,0.0022726508,0.00036656935,0.000075467025,0.00018280203,0.000030012972,0.00003516507,0.000010001066,0.0003985595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993346,0.000045759254,0.00021655828,0.0002487627,0.00006857155,0.00008576173],"domain_scores_gemma":[0.99951625,0.000060749702,0.000037250345,0.00025800383,0.00010227031,0.000025458337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022654855,0.000118942306,0.0001386603,0.000040789695,0.000016866563,0.0000127183885,0.00021871325,0.000104453895,0.0000631238],"category_scores_gemma":[0.00018169917,0.00006564377,0.000071674105,0.000034145753,0.000056000674,0.0000010485733,0.0005583107,0.00014821693,5.6582945e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010595316,0.0025690391,0.0005160615,0.003671052,0.0032527354,0.00072491873,0.12010549,0.04786177,0.47659498,0.006302152,0.054667175,0.2826751],"study_design_scores_gemma":[0.0016524317,0.0008344792,0.0032901072,0.0005144461,0.00015925197,0.004054792,0.023691025,0.009303934,0.77689266,0.00043780456,0.17804594,0.0011231301],"about_ca_topic_score_codex":0.0001411013,"about_ca_topic_score_gemma":0.002175324,"teacher_disagreement_score":0.30029768,"about_ca_system_score_codex":0.000008220105,"about_ca_system_score_gemma":0.0000946053,"threshold_uncertainty_score":0.26768753},"labels":[],"label_agreement":null},{"id":"W4243664412","doi":"10.1038/s41380-021-01055-8","title":"Correction to: Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders","year":2021,"lang":"en","type":"erratum","venue":"Molecular Psychiatry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Induced pluripotent stem cell; Neuroscience; Pathological; Psychology; Medicine; Biology; Pathology; Embryonic stem cell; Genetics","score_opus":0.007579673615404453,"score_gpt":0.27150408562767286,"score_spread":0.2639244120122684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243664412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.57874334,0.01873181,0.37857983,0.00070489646,0.017309496,0.005327111,0.00009793642,0.000032378393,0.00047321137],"genre_scores_gemma":[0.99308985,0.00041036741,0.0029174688,0.00026137446,0.0008346592,0.0015559383,0.00040141327,0.00009197156,0.00043695976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981599,0.00014663911,0.00036828863,0.00085313816,0.00022596522,0.0002460562],"domain_scores_gemma":[0.9990942,0.0000038131293,0.000097792916,0.0005722902,0.00009105209,0.00014086904],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009850283,0.00035468282,0.00033768313,0.00017062997,0.00005104192,0.000024041148,0.00020921667,0.0002457611,0.0000035352039],"category_scores_gemma":[0.000006287702,0.00036927324,0.00012322364,0.00035038637,0.000015050528,0.000001825034,0.00016856586,0.00047864043,8.2277774e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048205451,0.00914375,0.003492827,0.0014917856,0.00034021196,0.000049234164,0.0022750355,0.21313414,0.56322086,0.000116451156,0.06931691,0.13693674],"study_design_scores_gemma":[0.013925722,0.025145033,0.037301753,0.0019880023,0.0013324277,0.00007736193,0.020286001,0.021114143,0.5691104,0.0006185479,0.29833364,0.010766969],"about_ca_topic_score_codex":0.000026074746,"about_ca_topic_score_gemma":0.00049346936,"teacher_disagreement_score":0.41434652,"about_ca_system_score_codex":0.000020249077,"about_ca_system_score_gemma":0.00021332041,"threshold_uncertainty_score":0.9998759},"labels":[],"label_agreement":null},{"id":"W4243697403","doi":"10.31219/osf.io/wnhu9","title":"Homology Directed Repair in Zebrafish: Witchcraft and Wizardry?","year":2020,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Zebrafish; Mutagenesis; CRISPR; Computational biology; Gene; Biology; Mutant; Zinc finger; Genome editing; Genetics; Homology (biology); Zinc finger nuclease; Homology modeling; Model organism; Genetic screen; Genome","score_opus":0.009498215317748695,"score_gpt":0.28271832357965976,"score_spread":0.27322010826191107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243697403","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9816783,0.0051965145,0.0073594693,0.0011583099,0.0004768614,0.00045876345,0.00005567276,0.00024185117,0.0033742238],"genre_scores_gemma":[0.99228555,0.0006766744,0.005527634,0.00042703756,0.00024411472,0.000043287968,0.0001928665,0.000041478233,0.00056135224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873936,0.000041044164,0.0002445965,0.0006752195,0.000068457564,0.00023130818],"domain_scores_gemma":[0.99942374,0.0000111667805,0.000040995743,0.00039093217,0.000031303458,0.000101868456],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009366905,0.00024983275,0.00029144032,0.00006099073,0.000016476095,0.000013073944,0.00015462734,0.00043636377,0.00002635609],"category_scores_gemma":[0.00010516595,0.00026007884,0.00009908149,0.00006460832,0.000050829123,7.3487115e-7,0.00079935155,0.0003070537,0.0000042066517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027562564,0.00018516,0.03475245,0.0010164428,0.00059442496,0.00022460773,0.00052259583,0.0035812783,0.90490216,0.00027279364,0.050194893,0.0034775606],"study_design_scores_gemma":[0.0044975094,0.0012906438,0.24590583,0.00033589551,0.00028310943,0.0002856755,0.00039252223,0.023843633,0.50629455,0.003185652,0.20930609,0.004378899],"about_ca_topic_score_codex":0.00013650797,"about_ca_topic_score_gemma":0.00036061005,"teacher_disagreement_score":0.39860764,"about_ca_system_score_codex":0.000010666836,"about_ca_system_score_gemma":0.00006876762,"threshold_uncertainty_score":0.99998516},"labels":[],"label_agreement":null},{"id":"W4243702480","doi":"10.1186/s13007-019-0539-0","title":"Correction to: An optimised CRISPR/Cas9 protocol to create targeted mutations in homoeologous genes and an efficient genotyping protocol to identify edited events in wheat","year":2019,"lang":"en","type":"erratum","venue":"Plant Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"National Research Council Canada; Plant Biotechnology Institute; Communications Research Centre Canada; University of Ottawa; International Development Research Centre","funders":"","keywords":"CRISPR; Majesty; Protocol (science); Line (geometry); Genetics; Biology; Genotyping; Computational biology; Gene; Biotechnology; Computer science; Political science; Genotype; Medicine; Mathematics; Law","score_opus":0.021237802457908267,"score_gpt":0.4313073517547088,"score_spread":0.4100695492968005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243702480","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038969234,0.000087391265,0.28412107,0.000086363936,0.009884295,0.6661031,0.00025159513,0.00009243282,0.0004044766],"genre_scores_gemma":[0.0012749399,0.0000081891985,0.12711193,0.00019519191,0.0011013242,0.8650262,0.0014786853,0.0001399021,0.0036636721],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99698526,0.00057551486,0.0005947262,0.0010717497,0.00021389277,0.00055886403],"domain_scores_gemma":[0.9987881,0.0000555601,0.00011500891,0.0005726878,0.00012517723,0.00034344348],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010526889,0.00047354968,0.0005257556,0.00065187505,0.00008244184,0.00006177042,0.00032081667,0.000510604,0.00001634889],"category_scores_gemma":[0.00039852498,0.0004926523,0.00006772695,0.00044769,0.000016595886,0.000008879909,0.00022584884,0.00042754723,0.000007023579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011339965,0.00035375476,0.00088410726,0.00054718537,0.000058436162,0.000027823642,0.0011333876,0.24049954,0.7216457,8.774889e-7,0.01877731,0.014937846],"study_design_scores_gemma":[0.0046573263,0.0045302194,0.054781273,0.0017668997,0.00011520337,0.00016131326,0.00054554554,0.10386278,0.56981605,0.000020048717,0.2567747,0.0029686568],"about_ca_topic_score_codex":0.0003314566,"about_ca_topic_score_gemma":0.00084848696,"teacher_disagreement_score":0.23799737,"about_ca_system_score_codex":0.00009867324,"about_ca_system_score_gemma":0.00019309048,"threshold_uncertainty_score":0.9997525},"labels":[],"label_agreement":null},{"id":"W4244018144","doi":"10.24124/2013/bpgub952","title":"Investigating the 3' RNA Phosphodiesterase and 3'-5' Exoribonuclease Activities of APE1.","year":2013,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Heritage; University of Northern British Columbia; Library and Archives Canada","funders":"University of Northern British Columbia","keywords":"Exoribonuclease; Endoribonuclease; RNA; Biology; Exonuclease; AP site; Molecular biology; Polynucleotide phosphorylase; Messenger RNA; RNase H; Endonuclease; Biochemistry; Cell biology; DNA; RNase P; Gene; Enzyme; Polymerase","score_opus":0.006278355531077657,"score_gpt":0.2700716804891237,"score_spread":0.2637933249580461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244018144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99116725,0.002504261,0.00012226398,0.000021291611,0.00017718608,0.00015867339,0.000008583343,0.0000074953514,0.0058330074],"genre_scores_gemma":[0.9893915,0.0007507309,0.0005685483,0.00007574106,0.00011247533,0.000029339759,0.00022296354,0.00002996938,0.008818741],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942863,0.000014750924,0.00016591453,0.00018874681,0.00008214692,0.000119805714],"domain_scores_gemma":[0.9995795,0.000022501828,0.000088864545,0.00022109773,0.000040035193,0.00004801642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005669899,0.00016535586,0.00014255069,0.0000226702,0.000051019604,0.000026081247,0.0001007478,0.00014604804,0.00003525952],"category_scores_gemma":[0.00006733776,0.00012180526,0.000053050357,0.00002944541,0.000052865013,0.000002112494,0.00003998497,0.00009718685,0.0000013554633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012773982,0.000011812498,0.00016289075,0.0002424177,0.000073746545,3.4517225e-7,0.0007168399,0.000037071728,0.97990966,0.00010168026,0.0016761342,0.01705461],"study_design_scores_gemma":[0.00014561634,0.00006840388,0.0020024264,0.000058408295,0.000041058945,0.0000030760782,0.0032720994,0.00011783262,0.99154735,0.000046777317,0.0025033972,0.00019355572],"about_ca_topic_score_codex":0.00009296453,"about_ca_topic_score_gemma":0.0000943413,"teacher_disagreement_score":0.016861053,"about_ca_system_score_codex":0.000002652574,"about_ca_system_score_gemma":0.000034804874,"threshold_uncertainty_score":0.4967074},"labels":[],"label_agreement":null},{"id":"W4244026361","doi":"10.1038/srep25666","title":"Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centurion Biofuels (Canada); McMaster University; University of Waterloo","funders":"","keywords":"CRISPR; Genome editing; Cas9; Biology; Computational biology; Genome; Heterologous; Plasmid; In silico; Gene; Genetics","score_opus":0.01145641474261784,"score_gpt":0.2676898195738991,"score_spread":0.25623340483128126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244026361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738331,0.0012316166,0.022029169,0.00011676483,0.0023139974,0.00030233312,0.000013360887,0.000017666542,0.00014200606],"genre_scores_gemma":[0.99844974,0.000017827431,0.00076147326,0.000016635195,0.0002203425,0.000044049746,0.000045558834,0.00002207103,0.00042229836],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846214,0.000022728771,0.00033811587,0.00066412706,0.00013310704,0.000379767],"domain_scores_gemma":[0.9993212,0.000021261716,0.00010971189,0.0003954715,0.000068704394,0.00008364011],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007804439,0.00015255364,0.00015357521,0.00009712081,0.0001695488,0.00009962609,0.000083947714,0.00008652311,0.00000883162],"category_scores_gemma":[0.0001978325,0.00011846916,0.00006206534,0.00008876621,0.00015755408,0.0000048305606,0.00011802135,0.000042134026,0.0000010149398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002246032,0.000023231867,0.0038408842,0.00003538615,0.000009189612,0.000064392334,0.000096129734,0.00044855766,0.99008447,0.0000040600653,0.00021092278,0.0051603247],"study_design_scores_gemma":[0.0004659609,0.000081430604,0.0048164376,0.000045716515,0.00001538973,0.00074035715,0.00008777697,0.00030515384,0.96757305,0.00020620815,0.025377546,0.00028500214],"about_ca_topic_score_codex":0.000008423539,"about_ca_topic_score_gemma":0.000032049447,"teacher_disagreement_score":0.025166623,"about_ca_system_score_codex":0.00002082455,"about_ca_system_score_gemma":0.000050473678,"threshold_uncertainty_score":0.48310322},"labels":[],"label_agreement":null},{"id":"W4244053067","doi":"10.1007/3-540-29623-9_1020","title":"Cap‐Independent Translational Control","year":2005,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Control (management); Computer science; Artificial intelligence","score_opus":0.0060191396801908634,"score_gpt":0.2513347999367613,"score_spread":0.24531566025657042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244053067","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009543961,0.003954526,0.0655898,0.0002134373,0.0002336522,0.00021745583,0.00009018306,0.000023680695,0.9295818],"genre_scores_gemma":[0.12604943,0.00030319154,0.0006980379,0.00029475556,0.0011132321,0.0000070165547,0.0002812744,0.000054249846,0.87119883],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992466,0.000002842698,0.00017819162,0.00028170698,0.00014809851,0.00014257895],"domain_scores_gemma":[0.9996282,0.000004877658,0.00003328418,0.00022278202,0.00004104267,0.000069848866],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000048815567,0.0002112296,0.00015063219,0.00003474003,0.000023743458,0.000010751001,0.00010680989,0.00033711022,0.0015433776],"category_scores_gemma":[0.0000027147166,0.000209827,0.00015781357,0.0000028023837,0.00002314813,5.94998e-7,0.000017512199,0.00011885377,0.000096365104],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005536856,0.00018370972,0.0003588391,0.0002749014,0.0033696075,0.00008214846,0.0001732715,0.035683706,0.46479312,0.18691446,0.12741344,0.1801991],"study_design_scores_gemma":[0.0006234916,0.000062156476,0.00011886802,0.000011728671,0.000051350387,0.00002412111,0.0000013418779,0.00013076009,0.0062476676,0.00034440367,0.9920432,0.0003408978],"about_ca_topic_score_codex":0.0000019111599,"about_ca_topic_score_gemma":0.00007198939,"teacher_disagreement_score":0.86462975,"about_ca_system_score_codex":0.000006810532,"about_ca_system_score_gemma":0.00004729881,"threshold_uncertainty_score":0.9993693},"labels":[],"label_agreement":null},{"id":"W4244360800","doi":"10.1128/9781555818982.ch12","title":"The CRISPR-Cas Immune System and Genetic Transfers: Reaching an Equilibrium","year":2015,"lang":"en","type":"book-chapter","venue":"ASM Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Immune system; Biology; Genetics; Computational biology; Computer science; Gene","score_opus":0.024662216069762287,"score_gpt":0.282322677467472,"score_spread":0.25766046139770976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244360800","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011941062,0.117721386,0.009183205,0.00003598439,0.001154623,0.0013591673,0.00013783414,0.00017294633,0.8582938],"genre_scores_gemma":[0.7140165,0.0008045862,0.00045326914,0.00002714535,0.0011265674,0.00007468945,0.00011774947,0.00027285656,0.28310663],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985658,0.000041150957,0.00035907177,0.000507578,0.00020538841,0.00032104377],"domain_scores_gemma":[0.998797,0.000018350833,0.00008338106,0.0008430307,0.00008360873,0.00017464058],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021899356,0.00039212508,0.00029364892,0.00003117095,0.00012029326,0.000108025255,0.0003588071,0.00040749123,0.000001269664],"category_scores_gemma":[0.0000105815325,0.00032449726,0.00012100744,0.0000026777086,0.00012097278,0.000002647527,0.00017462458,0.0002722628,0.0000022929685],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006314833,0.000035366844,0.000010728868,0.001403882,0.0016005188,0.00021824495,0.0021346405,0.0011154452,0.7683519,0.051566765,0.0032637618,0.16966723],"study_design_scores_gemma":[0.0011357097,0.00089127553,0.000051789048,0.00036131384,0.00042876092,0.00045856816,0.00015611234,0.0007201835,0.15518296,0.00061639387,0.8386644,0.0013324968],"about_ca_topic_score_codex":0.000071198265,"about_ca_topic_score_gemma":0.000041755153,"teacher_disagreement_score":0.83540064,"about_ca_system_score_codex":0.000023032524,"about_ca_system_score_gemma":0.000053616444,"threshold_uncertainty_score":0.9999207},"labels":[],"label_agreement":null},{"id":"W4245189405","doi":"10.1002/9781118801512.index","title":"Index","year":2018,"lang":"en","type":"paratext","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Index (typography); Citation; Library science; Philosophy; Computer science; World Wide Web","score_opus":0.00632481834482473,"score_gpt":0.30429155655797896,"score_spread":0.2979667382131542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245189405","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0030941875,0.004088617,0.08723113,0.00003703061,0.0029441454,0.00015071916,0.00004534861,0.000013696513,0.9023951],"genre_scores_gemma":[0.062414486,0.00076281396,0.00051604834,0.0002500934,0.0030949216,0.000014651869,0.00066570385,0.000051775143,0.9322295],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993331,0.000007900129,0.00011439522,0.00028987526,0.000072269715,0.00018249865],"domain_scores_gemma":[0.999509,0.0000017620572,0.000027033922,0.00035978542,0.00004604452,0.00005639336],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00003748582,0.00017361535,0.00012287893,0.000033560067,0.000023868182,0.000017103337,0.00017479325,0.0003660931,0.003959302],"category_scores_gemma":[0.000009474691,0.0001613671,0.00007989456,0.000033522185,0.000033795477,2.3236173e-7,0.000114755545,0.000083595245,0.0045526144],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062954914,0.000006249255,0.000011030075,0.000020800935,0.000037460173,3.4312467e-7,0.000002948056,0.00008650644,0.022872472,0.0000023302787,0.976248,0.00070551597],"study_design_scores_gemma":[0.0000974647,0.00007907172,0.000036709447,0.000009566926,0.000006090905,0.0000055607816,0.0000046201903,0.000026077976,0.10219156,0.0000024493565,0.89733976,0.00020105623],"about_ca_topic_score_codex":0.000011416183,"about_ca_topic_score_gemma":0.000016542526,"teacher_disagreement_score":0.08671508,"about_ca_system_score_codex":0.0000047690555,"about_ca_system_score_gemma":0.000052330066,"threshold_uncertainty_score":0.9969512},"labels":[],"label_agreement":null},{"id":"W4245770225","doi":"10.1002/0471203076.emm0912","title":"<scp>Ca</scp> <sup>2+</sup> <scp>ATPases</scp>","year":2002,"lang":"en","type":"other","venue":"Wiley Encyclopedia of Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Citation; Encyclopedia; Library science; Computer science; World Wide Web; Information retrieval","score_opus":0.005572996840639429,"score_gpt":0.247406382166188,"score_spread":0.24183338532554857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245770225","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0106604295,0.098091386,0.010410227,0.00009604237,0.0010044123,0.0011372408,0.00023974346,0.0001690166,0.8781915],"genre_scores_gemma":[0.00920836,0.08856422,0.004143129,0.0011244926,0.0058785435,0.00029443548,0.0023466793,0.001912723,0.8865274],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961667,0.00012973267,0.0008192703,0.0011398578,0.0008507695,0.00089368917],"domain_scores_gemma":[0.9972293,0.00012311249,0.00043061268,0.0015870036,0.00014850486,0.0004814593],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030735665,0.0009899489,0.0011095051,0.00046612433,0.000051818755,0.000014145107,0.0008292863,0.0011053401,0.00054177595],"category_scores_gemma":[0.0016183803,0.000941553,0.00037460524,0.00037880836,0.00036886116,0.0000043080786,0.00028365714,0.0005146623,0.00014770188],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000026283158,0.000119334225,0.00019175623,0.00042985225,0.00037673497,0.00015147391,0.00023499744,0.0010976805,0.03353863,0.000028646946,0.9607935,0.0030347442],"study_design_scores_gemma":[0.001373024,0.00057659415,0.00006094465,0.00077298126,0.00035054135,0.0000655164,0.0002438445,0.00020787124,0.014092739,0.000027150985,0.98203033,0.00019847577],"about_ca_topic_score_codex":0.0001572677,"about_ca_topic_score_gemma":0.000018209685,"teacher_disagreement_score":0.021236794,"about_ca_system_score_codex":0.000027309721,"about_ca_system_score_gemma":0.000118315686,"threshold_uncertainty_score":0.9993035},"labels":[],"label_agreement":null},{"id":"W4246986313","doi":"10.1007/978-3-319-28755-3_17","title":"Rebooting the Genome","year":2016,"lang":"en","type":"book-chapter","venue":"Evolutionary Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Biology; Genetics; Genome; Meiosis; Dosage compensation; Heterogametic sex; Chromosome; Evolutionary biology; Gene","score_opus":0.007354087963401762,"score_gpt":0.23727324982259151,"score_spread":0.22991916185918976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246986313","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000068300586,0.0052509103,0.030763764,0.000334717,0.00047727287,0.0003481925,0.0002000968,0.000044772216,0.96251196],"genre_scores_gemma":[0.0068324753,0.0019553707,0.006344382,0.00047268166,0.0020100977,0.00001878685,0.0005533057,0.000102499005,0.9817104],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99905,0.000005435376,0.0003568268,0.0001619307,0.00019451341,0.00023125282],"domain_scores_gemma":[0.9991558,0.000018397244,0.00014892578,0.0005371976,0.00007640702,0.000063274885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330552,0.0002556436,0.00014583206,0.00004947537,0.00014671846,0.000017474676,0.0003001898,0.00028294476,0.0001334694],"category_scores_gemma":[0.000030348876,0.00017158527,0.00015929302,0.000013397051,0.00011478165,0.0000037726002,0.00022338149,0.00016038961,0.00030013474],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028270143,0.000090815854,0.00020030796,0.001578489,0.0028450156,0.000042621843,0.0014547586,0.0058618304,0.048523694,0.3539496,0.44942242,0.13574773],"study_design_scores_gemma":[0.0001466405,0.00007119978,0.00012188868,0.00006405185,0.00003194035,0.00007016333,0.000019359764,0.00039326548,0.00021725855,0.0012125397,0.9973263,0.00032535443],"about_ca_topic_score_codex":3.7526036e-7,"about_ca_topic_score_gemma":0.0000016707838,"teacher_disagreement_score":0.5479039,"about_ca_system_score_codex":0.00003599089,"about_ca_system_score_gemma":0.00008969211,"threshold_uncertainty_score":0.69970447},"labels":[],"label_agreement":null},{"id":"W4247412344","doi":"10.3410/f.1007767.107057","title":"Faculty Opinions recommendation of Sequence and structural conservation in RNA ribose zippers.","year":2002,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Ribose; Sequence (biology); RNA; Computational biology; Computer science; Biology; Genetics; Biochemistry; Gene","score_opus":0.027799341379059216,"score_gpt":0.37015379734836096,"score_spread":0.34235445596930175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247412344","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000039824776,0.002371425,0.000047002555,0.046744723,0.00034206422,0.00061193656,0.9498174,0.0000074383784,0.000018175071],"genre_scores_gemma":[0.00025927546,0.0010312233,0.0005323832,0.0015474231,0.00013768385,0.00006434449,0.99617296,0.000014608356,0.00024008953],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99787617,0.00016101814,0.0008402622,0.00045906974,0.00044873613,0.0002147675],"domain_scores_gemma":[0.99728125,0.000030901265,0.0005099214,0.0006979926,0.0013536033,0.00012634689],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048811652,0.0003121011,0.00044101704,0.00016209691,0.000078138444,0.00004650457,0.0005556274,0.00049733336,0.000077778],"category_scores_gemma":[0.0022877997,0.00022828321,0.00018968803,0.0006399971,0.00020592124,0.000024251416,0.000265829,0.0004371856,0.000003072918],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000067697233,0.00004674164,0.000026760621,0.0023641116,0.000041559895,1.3492571e-7,0.000044630513,0.0000010182115,0.00016583559,0.000024036963,0.9954795,0.0017988741],"study_design_scores_gemma":[0.00044852798,0.000089376335,0.002731439,0.0025514308,0.000046510053,0.000029814993,0.000017338542,0.00006664056,0.00030417932,0.000008246076,0.99348176,0.00022475957],"about_ca_topic_score_codex":0.00006810133,"about_ca_topic_score_gemma":0.000021420867,"teacher_disagreement_score":0.04635556,"about_ca_system_score_codex":0.000035415458,"about_ca_system_score_gemma":0.00013812345,"threshold_uncertainty_score":0.93091196},"labels":[],"label_agreement":null},{"id":"W4247523580","doi":"10.1038/s41594-019-0258-2","title":"Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9","year":2019,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":174,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; National Cancer Institute; Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston; National Institute of General Medical Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canada Research Chairs","keywords":"Nuclease; Cas9; DNA; Endonuclease; Guide RNA; Chemistry; Cleavage (geology); Biophysics; CRISPR; Biology; Biochemistry","score_opus":0.0022895994388970114,"score_gpt":0.29441762419920003,"score_spread":0.29212802476030303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247523580","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879459,0.0045295507,0.0045830654,0.00032252137,0.0010069971,0.00042940915,0.0003166214,0.00005610294,0.00080983347],"genre_scores_gemma":[0.9954663,0.000038393453,0.0013185582,0.0009554614,0.00018758165,0.000011993559,0.0014057221,0.000064481945,0.00055152964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979565,0.00013466708,0.00028631784,0.0008195836,0.00018430626,0.00061858865],"domain_scores_gemma":[0.9989357,0.000012440141,0.00012808827,0.00067542307,0.00008737982,0.00016098957],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011343144,0.00045323756,0.0003747262,0.00007426314,0.00010960578,0.000042849664,0.0004818316,0.001134044,0.00010620835],"category_scores_gemma":[0.000071503986,0.00039968552,0.00022030908,0.00017586761,0.00011319015,0.0000068433355,0.00023381149,0.0006632657,0.000016478914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051976276,0.0000072768403,0.0014648987,0.000026398286,0.000112461035,0.000011889278,0.000027903467,0.00012875661,0.9899562,0.0017388532,0.0053463746,0.0011270344],"study_design_scores_gemma":[0.001269298,0.00041218763,0.016117197,0.000012606845,0.000047343932,0.00018656033,0.0001350389,0.000050204813,0.95792216,0.0026349118,0.020483099,0.00072942016],"about_ca_topic_score_codex":0.000035125948,"about_ca_topic_score_gemma":0.000024898502,"teacher_disagreement_score":0.032034043,"about_ca_system_score_codex":0.00004234835,"about_ca_system_score_gemma":0.00004366128,"threshold_uncertainty_score":0.9998455},"labels":[],"label_agreement":null},{"id":"W4247938729","doi":"10.21236/ada462348","title":"Non-Invasive Gene Therapy of Experimental Parkinson's Disease","year":2006,"lang":"en","type":"report","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University of California, Davis; U.S. Department of Defense","keywords":"Disease; Genetic enhancement; Parkinson's disease; Medicine; Gene; Biology; Neuroscience; Genetics; Internal medicine","score_opus":0.012714448377468166,"score_gpt":0.3098240765218661,"score_spread":0.29710962814439795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247938729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85314214,0.08814894,0.004723173,0.000023488197,0.0011873619,0.0007387114,0.00027028672,0.00003264315,0.051733255],"genre_scores_gemma":[0.97893816,0.011500757,0.00060231955,0.00003703544,0.0008683634,0.000056008874,0.0010319501,0.00006451404,0.0069008856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878824,0.000009303522,0.00028030734,0.0004113199,0.00030082263,0.00020999635],"domain_scores_gemma":[0.999142,0.000004846302,0.00011518512,0.000491596,0.00013801578,0.00010836837],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008240403,0.00028384358,0.0002730663,0.000052912535,0.00002368349,0.000009859762,0.00017829846,0.00023118165,0.00006946293],"category_scores_gemma":[0.000018217946,0.00026008484,0.0002618755,0.000040971656,0.000050072857,7.683334e-7,0.00008819441,0.00007415364,0.0000030024487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056223733,0.0001366684,0.002282809,0.00006336473,0.00013237707,0.000016240205,0.000009547955,0.00026738358,0.950675,0.0000011810237,0.045522187,0.00083698845],"study_design_scores_gemma":[0.00026993765,0.00011649046,0.0037096557,0.000020895272,0.000013743649,0.0000070710857,0.000011018039,0.0000075151897,0.7529225,0.000001583382,0.24268188,0.00023775661],"about_ca_topic_score_codex":0.0001515206,"about_ca_topic_score_gemma":0.000018451568,"teacher_disagreement_score":0.19775258,"about_ca_system_score_codex":0.000024665524,"about_ca_system_score_gemma":0.00051827275,"threshold_uncertainty_score":0.99998516},"labels":[],"label_agreement":null},{"id":"W4247974917","doi":"10.3410/f.718215521.793511222","title":"Faculty Opinions recommendation of Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.","year":2015,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"CRISPR; Computational biology; Computer science; Data science; Biology; Genetics; Gene","score_opus":0.01414586397955677,"score_gpt":0.36109696197771757,"score_spread":0.3469510979981608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247974917","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000036979178,0.003311125,0.0005832021,0.0049790903,0.00041669948,0.0008685906,0.9897697,0.000013942044,0.000020683612],"genre_scores_gemma":[0.0012142577,0.00032956476,0.001033075,0.00028148072,0.000112954716,0.00008803783,0.99674475,0.000034193563,0.0001616966],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99672604,0.00036911503,0.0014203773,0.0005947925,0.00059470086,0.00029500097],"domain_scores_gemma":[0.9954348,0.000034247667,0.0010081024,0.0012064066,0.002110905,0.00020550784],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014127594,0.00041801258,0.00079642306,0.00025262363,0.00008164935,0.000051818122,0.0011407044,0.00048905105,0.000049513834],"category_scores_gemma":[0.0009898194,0.00032736044,0.0003371543,0.0005622365,0.00017303246,0.000029155546,0.0004420026,0.0004765917,0.0000041531794],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009288661,0.00021134035,0.000006487636,0.0052202204,0.00006838145,1.4401485e-7,0.000085394786,0.000009006314,0.0023997247,0.000005702585,0.99155366,0.00043062595],"study_design_scores_gemma":[0.00062534283,0.00012132982,0.00044054425,0.0049757203,0.00010643732,0.000018236988,0.00011362677,0.00017109822,0.0011454908,0.0000014785,0.99196464,0.00031606248],"about_ca_topic_score_codex":0.0001186988,"about_ca_topic_score_gemma":0.000015903686,"teacher_disagreement_score":0.0069750515,"about_ca_system_score_codex":0.000116623756,"about_ca_system_score_gemma":0.00027069193,"threshold_uncertainty_score":0.99991786},"labels":[],"label_agreement":null},{"id":"W4248164199","doi":"10.1504/ijarge.2018.097986","title":"Top plant breeding techniques for improving food security: an expert Delphi survey of the opportunities and challenges","year":2018,"lang":"en","type":"article","venue":"International Journal of Agricultural Resources Governance and Ecology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Food security; Delphi method; Agriculture; Delphi; Business; Population; Sustainable agriculture; Biotechnology; Environmental resource management; Environmental planning; Natural resource economics; Geography; Computer science; Biology; Economics; Environmental health; Ecology; Medicine","score_opus":0.02966336104516624,"score_gpt":0.27992154261374325,"score_spread":0.250258181568577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248164199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99416107,0.0045544985,0.00007318487,0.00081837876,0.00023632938,0.00005451025,0.000053588934,0.0000018394979,0.00004659402],"genre_scores_gemma":[0.99209243,0.007055167,0.00021245293,0.00008417509,0.0005231036,0.0000030446124,0.000006019733,0.0000040976174,0.000019525032],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995096,0.000023740611,0.00018488121,0.000095255564,0.00009881714,0.000087714],"domain_scores_gemma":[0.99935997,0.000036214802,0.00022206087,0.00004610167,0.000301828,0.00003383335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039404,0.000072998664,0.00010789113,0.000016169995,0.00004126595,0.000017905635,0.00018728066,0.000068072215,0.0000017618698],"category_scores_gemma":[0.00012102621,0.000044206277,0.00003608981,0.00001335844,0.00008319096,0.000013510354,0.00009388295,0.00004647263,1.4453837e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013426056,0.00020574138,0.032548837,0.00016236897,0.00081491686,0.000008283046,0.00926311,0.00004211617,0.7939693,0.002025299,0.0031236366,0.15649384],"study_design_scores_gemma":[0.00061526196,0.0036595967,0.76568586,0.000081561266,0.000023294637,0.00052531436,0.0026744953,0.00007402017,0.19316015,0.00008203099,0.033228725,0.00018970862],"about_ca_topic_score_codex":0.00004339285,"about_ca_topic_score_gemma":0.00092757563,"teacher_disagreement_score":0.733137,"about_ca_system_score_codex":0.000009553619,"about_ca_system_score_gemma":0.000016067717,"threshold_uncertainty_score":0.18026797},"labels":[],"label_agreement":null},{"id":"W4249221593","doi":"10.21203/rs.3.rs-765771/v1","title":"Development of a gRNA-tRNA Array of CRISPR/Cas9 in Combination with Grafting Technique to Improve Gene Editing Efficiency of Sweet Orange","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Fundamental Research Funds for the Central Universities; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"CRISPR; Guide RNA; Genome editing; Orange (colour); Transfer RNA; Computational biology; Biology; Computer science; Gene; Genetics; Horticulture; RNA","score_opus":0.020156718836767847,"score_gpt":0.366148486894191,"score_spread":0.34599176805742315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249221593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8356759,0.00065527967,0.16253677,0.000025074638,0.000052294316,0.00087674527,0.00002882567,0.0000052066694,0.00014388745],"genre_scores_gemma":[0.95518786,0.00006392279,0.04428657,0.0000019947672,0.00005557123,0.00022120477,0.00013381094,0.000029301293,0.000019763596],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797726,0.00010940631,0.0005450404,0.00045913688,0.0005661694,0.00034301804],"domain_scores_gemma":[0.9984068,0.000036293415,0.00017010022,0.00046095302,0.00084984367,0.00007599751],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014271517,0.00018106303,0.00035432342,0.00035536496,0.000036070393,0.000013989393,0.00031014782,0.00024106097,0.000006017325],"category_scores_gemma":[0.00038244898,0.00017901839,0.00007397207,0.00041895357,0.00006615076,0.0000031592485,0.0005739999,0.00038597672,2.1431724e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053755426,0.0001721272,0.0014138069,0.0019023004,0.000037323945,0.0000048777797,0.0011460636,0.0016233331,0.9906923,0.000008768098,0.000007619776,0.0029377318],"study_design_scores_gemma":[0.00035769207,0.00038125025,0.0028399788,0.0012170823,0.0000060318107,0.0000025231766,0.001087315,0.000095612486,0.9937341,0.000010455391,0.000109069864,0.00015889354],"about_ca_topic_score_codex":0.000142514,"about_ca_topic_score_gemma":0.00018660228,"teacher_disagreement_score":0.11951195,"about_ca_system_score_codex":0.00006237327,"about_ca_system_score_gemma":0.0005145789,"threshold_uncertainty_score":0.7300158},"labels":[],"label_agreement":null},{"id":"W4249760952","doi":"10.1177/153567600901400303","title":"Erratum: Cover Art in <i>Applied Biosafety</i> (Volume 14, Number 2, 2009)","year":2009,"lang":"en","type":"erratum","venue":"Applied Biosafety","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biosafety; Biosecurity; Biological safety; Political science; Engineering; Biotechnology; Biology; Ecology","score_opus":0.004467984477639255,"score_gpt":0.247161226605055,"score_spread":0.24269324212741575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249760952","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003484953,0.0022615462,0.0023842147,0.0009003395,0.007943044,0.0013729945,0.0004862406,0.00016415042,0.98413897],"genre_scores_gemma":[0.40495127,0.0074230325,0.0024490263,0.0045809103,0.007369367,0.0003533761,0.019563992,0.00057185156,0.5527372],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99567604,0.000041148895,0.0009658433,0.0016031378,0.0005279289,0.0011858806],"domain_scores_gemma":[0.99788857,0.00001601157,0.0002869494,0.001437345,0.00008059806,0.00029055472],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00038934132,0.0011053043,0.0009656708,0.00018105077,0.0001250414,0.00007961837,0.0007971014,0.002238744,0.0003621045],"category_scores_gemma":[0.00002822515,0.0011828219,0.00034886974,0.0005023615,0.0001606999,0.0000045191864,0.00036008458,0.0013524634,0.001442267],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002010009,0.00016436118,0.00003088069,0.00010400302,0.00011676392,0.000021156195,0.00002892102,0.00030352743,0.042696144,0.0006740678,0.9535578,0.0021014097],"study_design_scores_gemma":[0.0013911959,0.00009249931,0.0035632125,0.0000754857,0.00008253588,0.000029100358,0.00002920021,0.000044692173,0.009773661,0.00018975892,0.98330027,0.0014283771],"about_ca_topic_score_codex":0.000016651406,"about_ca_topic_score_gemma":0.00009969463,"teacher_disagreement_score":0.43140182,"about_ca_system_score_codex":0.00010116423,"about_ca_system_score_gemma":0.00033501827,"threshold_uncertainty_score":0.9993352},"labels":[],"label_agreement":null},{"id":"W4250346587","doi":"10.1038/npg.els.0003648","title":"Invertebrate Metabolism","year":2003,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Invertebrate; Ecology; Zoology; Biology","score_opus":0.008282207521137836,"score_gpt":0.27637649701329553,"score_spread":0.2680942894921577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250346587","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001023802,0.02316425,0.000977492,0.000032947362,0.000980853,0.000114208495,0.000023523053,0.000018217193,0.9736647],"genre_scores_gemma":[0.0047688815,0.023308767,0.0083116405,0.00035593074,0.0012732797,0.000020238967,0.000035479017,0.00021323204,0.96171254],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990863,0.000029360404,0.000173811,0.0003227437,0.00018909363,0.00019866913],"domain_scores_gemma":[0.9995404,0.0000051932266,0.00011348989,0.00023694907,0.00001623558,0.00008777035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016672366,0.00017201368,0.0002147679,0.000112754904,0.000028151859,0.000006728546,0.00030875468,0.00017203522,0.00048997],"category_scores_gemma":[0.000113927905,0.0001491763,0.00007525048,0.00015854885,0.00020904759,0.0000013419115,0.000060309747,0.00005727473,0.00002526085],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000019254633,0.000019003426,0.0007157128,0.000046280344,0.000042803127,5.7209434e-7,0.000022223825,0.000060977483,0.003608936,0.00020412698,0.9944045,0.0008729443],"study_design_scores_gemma":[0.000110982335,0.0000435987,0.0001027825,0.00001927909,0.000015455567,0.000001292553,0.000027473578,0.00001048731,0.004243776,0.000030936033,0.9952015,0.0001923996],"about_ca_topic_score_codex":0.00005960108,"about_ca_topic_score_gemma":0.0000676792,"teacher_disagreement_score":0.011952156,"about_ca_system_score_codex":0.0000013678293,"about_ca_system_score_gemma":0.00017586975,"threshold_uncertainty_score":0.6083233},"labels":[],"label_agreement":null},{"id":"W4251132686","doi":"10.1007/s11568-010-9137-y","title":"Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing","year":2009,"lang":"en","type":"article","venue":"The HUGO Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Sanger sequencing; Amplicon; Genetics; Biology; Genome; Multiplex; Massive parallel sequencing; DNA sequencing; Cancer genome sequencing; Gene; Computational biology; Deep sequencing; Reference genome; Multiplex polymerase chain reaction; Human genome; Multiplex ligation-dependent probe amplification; Mutation; Whole genome sequencing; Amplicon sequencing; Polymerase chain reaction; Exon","score_opus":0.013569703154628092,"score_gpt":0.2809215113440629,"score_spread":0.2673518081894348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251132686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91637206,0.0024322283,0.08031683,0.0006545514,0.000060926275,0.00011281689,0.0000046267583,0.0000058284513,0.000040162282],"genre_scores_gemma":[0.99458325,0.00027242996,0.004685222,0.0001875301,0.00014878457,0.000002858308,0.00006586437,0.000009184687,0.000044849323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993619,0.00005513731,0.00018437089,0.00012949189,0.0001070112,0.0001621243],"domain_scores_gemma":[0.9997409,0.000011206363,0.00007450978,0.00009122803,0.000031310137,0.000050828632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024950237,0.00010235276,0.0000832929,0.00003957819,0.00012520282,0.000045318677,0.00008209581,0.00006113139,0.000008479187],"category_scores_gemma":[0.00003217125,0.00008224273,0.000037987276,0.00004791562,0.000025099214,0.0000070529995,0.000015183908,0.00013308757,7.3085283e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000663903,0.000011070856,0.0007198235,0.000003236991,0.000014923484,0.000006640843,0.00022746628,0.017742088,0.9600572,0.000005874089,0.00023440817,0.020910863],"study_design_scores_gemma":[0.006107962,0.00084631337,0.06256474,0.00015483267,0.000075469005,0.0005294792,0.0018777897,0.20067298,0.72055924,0.0003967429,0.0054813046,0.0007331407],"about_ca_topic_score_codex":0.000012273117,"about_ca_topic_score_gemma":0.000019099005,"teacher_disagreement_score":0.23949797,"about_ca_system_score_codex":0.000020680862,"about_ca_system_score_gemma":0.000028583818,"threshold_uncertainty_score":0.33537614},"labels":[],"label_agreement":null},{"id":"W4251139549","doi":"10.1385/1-59259-958-3:107","title":"Yeast Transformation by the LiAc/SS Carrier DNA/PEG Method","year":2005,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":343,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"","keywords":"Transformation (genetics); Transformation efficiency; Plasmid; Yeast; Computer science; PEG ratio; DNA; Protocol (science); Computational biology; Biology; Genetics; Gene; Medicine","score_opus":0.017028740794758294,"score_gpt":0.3148971684996952,"score_spread":0.2978684277049369,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251139549","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25144324,0.02617303,0.44096836,0.0004996362,0.00096224336,0.0015077647,0.00027242646,0.00017478991,0.2779985],"genre_scores_gemma":[0.9874292,0.00011524515,0.0007460436,0.00025309648,0.00038418893,0.00005448331,0.000055400527,0.000025883832,0.010936465],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993947,0.000034394296,0.00013895618,0.00016145955,0.000095593015,0.00017487252],"domain_scores_gemma":[0.9996302,0.0000049460436,0.000025873538,0.00026756455,0.000024382865,0.00004704338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012894731,0.000113888156,0.0000765013,0.000012479529,0.00008782987,0.00003086715,0.00016809569,0.00008014776,0.000013972375],"category_scores_gemma":[0.0000055667106,0.000090373214,0.000065011496,0.000006979183,0.00003004188,0.0000025086479,0.000033262,0.00007678972,0.000003145517],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035798592,0.000024038729,0.0000024918138,0.000042221174,0.00010713853,7.097419e-7,0.001963328,0.0020057631,0.72484595,0.0016164104,0.026909826,0.24244632],"study_design_scores_gemma":[0.00015434352,0.000019364517,0.000020550326,0.0000028419513,0.00001475673,0.000004306419,0.000032275853,0.00044183078,0.47105664,0.0000090243075,0.5281644,0.00007968845],"about_ca_topic_score_codex":0.000033963082,"about_ca_topic_score_gemma":0.000057555924,"teacher_disagreement_score":0.73598593,"about_ca_system_score_codex":0.000006448582,"about_ca_system_score_gemma":0.000009266079,"threshold_uncertainty_score":0.3685313},"labels":[],"label_agreement":null},{"id":"W4251520346","doi":"10.1038/npre.2012.6965","title":"Quantitative Models for Efficient Cloning of Different Vectors with Various Clone sites","year":2012,"lang":"en","type":"preprint","venue":"Nature Precedings","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cloning (programming); clone (Java method); Restriction enzyme; Transformation (genetics); Ligation; Computational biology; Restriction digest; Restriction site; Biology; Cloning vector; Molecular biology; Vector (molecular biology); Library; Molecular cloning; Genetics; DNA; Recombinant DNA; Gene; Computer science; Peptide sequence","score_opus":0.012071258346012487,"score_gpt":0.30664294754288274,"score_spread":0.29457168919687027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251520346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8294789,0.0075642117,0.16147989,0.000034544282,0.00047293658,0.0006035156,0.00010282043,0.000023191526,0.00023995384],"genre_scores_gemma":[0.9816046,0.00013218888,0.017388547,0.000022130098,0.00025478494,0.000104303595,0.0003726806,0.000062551015,0.000058208298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986871,0.000017766972,0.0002531822,0.0005018331,0.00020133806,0.00033877208],"domain_scores_gemma":[0.99907523,0.00005495038,0.00020411919,0.00033520674,0.00023730783,0.00009320806],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016280533,0.00035615283,0.00038806742,0.00008271973,0.000045581473,0.000021990361,0.00025286243,0.0007924008,0.0000030858719],"category_scores_gemma":[0.000093228,0.00029060294,0.00017721583,0.00005847567,0.00005364604,0.0000020998093,0.0003277573,0.0005849858,2.48753e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052216806,0.00014827031,0.0006651842,0.0007739976,0.00043356037,5.020192e-7,0.0011274951,0.13609198,0.8583448,0.0013450587,0.00028735684,0.00025962034],"study_design_scores_gemma":[0.000740081,0.0006105956,0.0010084225,0.00032449453,0.00026954553,0.000007262705,0.000107760156,0.028447067,0.9671089,0.00044146532,0.0003180138,0.00061638776],"about_ca_topic_score_codex":0.000010211106,"about_ca_topic_score_gemma":0.000013728813,"teacher_disagreement_score":0.15212567,"about_ca_system_score_codex":0.000028063181,"about_ca_system_score_gemma":0.00004637935,"threshold_uncertainty_score":0.99995464},"labels":[],"label_agreement":null},{"id":"W4252213096","doi":"10.1385/1-59259-194-9:189","title":"Transplacement Mutagenesis","year":2002,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Subcloning; Mutagenesis; Genetics; Biology; Plasmid; Gene; DNA; Mutation; Computational biology","score_opus":0.0335892430482967,"score_gpt":0.277345931998791,"score_spread":0.2437566889504943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252213096","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010127796,0.017801913,0.0021984812,0.000004500785,0.00022550134,0.00030443084,0.000053344294,0.000038511313,0.97927207],"genre_scores_gemma":[0.012600613,0.0030485634,0.0001790698,0.00007947146,0.0005726271,0.00003703462,0.00011710162,0.000119408294,0.9832461],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99889094,0.000007345455,0.0002415183,0.00045178266,0.00016996633,0.00023847463],"domain_scores_gemma":[0.9992456,0.0000038544194,0.00006585924,0.00055855315,0.000035698537,0.000090468835],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000047847523,0.000348869,0.00022701098,0.000046698693,0.00006128791,0.000025042682,0.00023044791,0.00034233,0.00025740403],"category_scores_gemma":[0.0000018603384,0.00037899875,0.00020095671,0.0000014522025,0.00005624722,5.5069233e-7,0.00008163562,0.00013883787,0.000022155542],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040470067,0.00018499252,0.0000040657665,0.002651651,0.0048959455,0.00042550662,0.0015306573,0.0034557981,0.13277365,0.18214291,0.1562976,0.5152325],"study_design_scores_gemma":[0.00028180407,0.000105201056,0.0000028138177,0.000052974592,0.00012332648,0.000008953496,0.0000014409462,0.000024590909,0.040697966,0.000099558674,0.9581753,0.000426049],"about_ca_topic_score_codex":0.000009636994,"about_ca_topic_score_gemma":0.000017522076,"teacher_disagreement_score":0.80187774,"about_ca_system_score_codex":0.000012641471,"about_ca_system_score_gemma":0.000012364183,"threshold_uncertainty_score":0.9998662},"labels":[],"label_agreement":null},{"id":"W4252473439","doi":"10.22215/etd/2017-11975","title":"Harnessing New Genomics Technologies to Assess Environmental Risk Factors That May Cause Heritable Genetic Disease","year":2017,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"Offspring; Biology; Genetics; Germline mutation; Germline; Mutation; Sperm; Mutagen; Somatic cell; Gene; Carcinogen; Pregnancy","score_opus":0.018682644777153565,"score_gpt":0.2982302839471086,"score_spread":0.279547639169955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252473439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908288,0.004141873,0.0030403093,0.000028983233,0.0004936973,0.00037237766,0.00014463007,0.00007632887,0.0008730084],"genre_scores_gemma":[0.95585907,0.003558871,0.0017176246,0.000014591769,0.00012970675,0.000032951888,0.0017406843,0.000097371,0.036849122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985748,0.00001538046,0.00020659914,0.0006555994,0.000163878,0.00038373054],"domain_scores_gemma":[0.9987074,0.0000075123803,0.00013249928,0.0009153286,0.000009521069,0.00022774548],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000039997314,0.00043688327,0.00026636443,0.00008437627,0.00022353281,0.0001725007,0.00050941313,0.00041242587,0.0001294793],"category_scores_gemma":[0.000054395547,0.00042743134,0.00015278692,0.000025786963,0.00003374299,0.000005680363,0.000105384854,0.0001938655,0.000024113104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035809606,0.00016373175,0.13882865,0.00022967976,0.0006352233,0.000055151388,0.0004565003,0.007668313,0.7039884,0.0000065207073,0.006704227,0.14090553],"study_design_scores_gemma":[0.00035675103,0.00011316607,0.1587529,0.000066062705,0.00031722416,0.000004400658,0.0018342438,0.00010429039,0.7628354,0.000076179356,0.07434626,0.001193128],"about_ca_topic_score_codex":0.00015718999,"about_ca_topic_score_gemma":0.00024749245,"teacher_disagreement_score":0.1397124,"about_ca_system_score_codex":0.000044067696,"about_ca_system_score_gemma":0.00013673324,"threshold_uncertainty_score":0.9998177},"labels":[],"label_agreement":null},{"id":"W4253036937","doi":"10.1385/1-59259-270-8:539","title":"Gene Transfer in Avian Embryos Using Replication- Competent Retroviruses","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Subcloning; Biology; Rous sarcoma virus; Gene; Plasmid; Virology; Genetics; Retrovirus; Replicon; Provirus; Integrase; Molecular biology; Genome","score_opus":0.04619664968266841,"score_gpt":0.3181515203814027,"score_spread":0.2719548706987343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253036937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9736068,0.0031908257,0.014029773,0.000002800563,0.00009626316,0.00023580284,0.000007259049,0.000017851997,0.00881259],"genre_scores_gemma":[0.99814487,0.00009215698,0.001069097,0.000075061966,0.00006337266,0.000024492845,0.00001344975,0.000023903995,0.00049359316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919176,0.00003652301,0.0001845706,0.00031899623,0.0000758189,0.00019233415],"domain_scores_gemma":[0.99941504,0.000003886214,0.000016289421,0.0004903198,0.000024982368,0.000049497856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010748363,0.00011888559,0.00010511681,0.000036426387,0.00004594844,0.000017898374,0.00011247681,0.00007974171,0.000008535674],"category_scores_gemma":[0.000017781525,0.000128742,0.000051951607,0.00001305545,0.00003083594,0.0000013768483,0.000021577542,0.00006856001,0.0000010330426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020154497,0.00003043639,0.0004261807,0.000029479155,0.000029606652,0.000006202862,0.00016351332,0.0013442815,0.99440765,0.0015876566,0.00005441298,0.0019004409],"study_design_scores_gemma":[0.00041519088,0.000053390115,0.0014961235,0.00001382921,0.000015119518,0.000015977872,0.000019980816,0.0001889266,0.9661916,0.000030743304,0.03136206,0.00019706236],"about_ca_topic_score_codex":0.0000779152,"about_ca_topic_score_gemma":0.000072493,"teacher_disagreement_score":0.031307645,"about_ca_system_score_codex":0.000012580211,"about_ca_system_score_gemma":0.00002108962,"threshold_uncertainty_score":0.5249947},"labels":[],"label_agreement":null},{"id":"W4253446019","doi":"10.12688/gatesopenres.13221.1","title":"Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria","year":2021,"lang":"en","type":"preprint","venue":"Gates Open Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Open Philanthropy Project; Silicon Valley Community Foundation; Bill and Melinda Gates Foundation","keywords":"Malaria; Gene drive; Medical research; Control (management); Political science; Medicine; Biology; Biotechnology; Computer science; Gene; Immunology; Genetics; Artificial intelligence","score_opus":0.12697424514933703,"score_gpt":0.4605490228737494,"score_spread":0.33357477772441235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253446019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911454,0.0024631324,0.00012551459,0.00061215844,0.000048839975,0.0027247348,0.0002135525,0.0000053842805,0.0026613134],"genre_scores_gemma":[0.9892125,0.0019902275,0.0055442727,0.00002489502,0.00010109978,0.00094534486,0.0013645827,0.000060872448,0.00075620506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99711907,0.00041347006,0.0003675885,0.0007769323,0.0005845079,0.0007384346],"domain_scores_gemma":[0.99798423,0.00021036925,0.00006237726,0.0007092357,0.00082179025,0.00021199539],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0054254285,0.0002516405,0.000406656,0.000229154,0.00027735048,0.0003781906,0.0014156606,0.00046743065,0.000050169583],"category_scores_gemma":[0.0004482956,0.0002586518,0.000059626,0.00026783062,0.00024563176,0.000009613431,0.003827569,0.0014566595,0.0000013156958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004950385,0.0005587003,0.00047002392,0.00040267268,0.00010229618,0.0000047549483,0.0028978854,0.00012580762,0.98142403,0.000044913795,0.012209786,0.0012640898],"study_design_scores_gemma":[0.0010450577,0.0009269061,0.0012729041,0.00035478637,0.000004939305,0.0000023445323,0.009587266,0.00051558076,0.9789719,0.00040278336,0.006608056,0.00030745752],"about_ca_topic_score_codex":0.0007902197,"about_ca_topic_score_gemma":0.00013476291,"teacher_disagreement_score":0.00668938,"about_ca_system_score_codex":0.0000843989,"about_ca_system_score_gemma":0.00026295905,"threshold_uncertainty_score":0.9999866},"labels":[],"label_agreement":null},{"id":"W4253542280","doi":"10.17504/protocols.io.x36fqre","title":"Tranfection of SpCas9 containing plasmids to generate cell lines with Cas9 v1","year":2019,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Plasmid; CRISPR; Computer science; Biology; Genetics; Gene","score_opus":0.007955930778892336,"score_gpt":0.2723668526327777,"score_spread":0.2644109218538854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253542280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8586631,0.0004317509,0.13728243,0.000032516713,0.0003814845,0.00032630903,0.000028760627,0.000016789956,0.002836862],"genre_scores_gemma":[0.9919352,0.00011938145,0.0056879125,0.000067780515,0.00028061031,0.000027902784,0.00014615266,0.00004208328,0.0016929547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990102,0.000018025481,0.00023237405,0.00043660848,0.00010754213,0.00019525453],"domain_scores_gemma":[0.9993151,0.000007250334,0.00007460361,0.00040668756,0.000119534045,0.00007684121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009624529,0.00024840774,0.00027121574,0.00007066855,0.000018961522,0.00001964874,0.00014098235,0.0002729717,0.000023426457],"category_scores_gemma":[0.000009723098,0.00021629926,0.000096894975,0.00005193088,0.00001741411,9.065563e-7,0.00017547872,0.00015073988,0.0000074181994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013665624,0.000029135677,0.0011610063,0.00022621945,0.00008431798,0.0000021049316,0.00008322015,0.28812167,0.7091047,0.000006658855,0.0004239459,0.0006203115],"study_design_scores_gemma":[0.00043143498,0.00065622065,0.00055765023,0.000058801663,0.000052172112,0.000010094185,0.00006784427,0.0017702633,0.9926301,0.000003336349,0.0034454395,0.00031662342],"about_ca_topic_score_codex":0.000118181786,"about_ca_topic_score_gemma":0.00014809269,"teacher_disagreement_score":0.2863514,"about_ca_system_score_codex":0.000010817037,"about_ca_system_score_gemma":0.000095464165,"threshold_uncertainty_score":0.88204277},"labels":[],"label_agreement":null},{"id":"W4254779871","doi":"10.1016/s0378-1097(02)00893-5","title":"Impact of feed processing and mixed ruminal culture on the fate of recombinant EPSP synthase and endogenous canola plant DNA","year":2002,"lang":"en","type":"article","venue":"FEMS Microbiology Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Food Inspection Agency","keywords":"Canola; Recombinant DNA; Biology; Endogeny; Rumen; Biochemistry; DNA; DNA shuffling; Exogenous DNA; Genetically modified organism; Food science; Gene; Fermentation; Mutant","score_opus":0.011564532438143295,"score_gpt":0.23257101757314236,"score_spread":0.22100648513499907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254779871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974477,0.0019487592,0.00007486397,0.0002284746,0.00007371288,0.0001230565,0.000073273775,0.0000038605276,0.000026241423],"genre_scores_gemma":[0.99944043,0.00023216291,0.0000782537,0.00013352091,0.000027451442,0.000004638906,0.00004578812,0.000010775683,0.000026993603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999388,0.000039761515,0.00015567307,0.00020342422,0.000021151027,0.00019198847],"domain_scores_gemma":[0.99970096,0.000017472565,0.00008461076,0.0001460807,0.000017470662,0.000033420358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075790864,0.00014470016,0.00017465072,0.000032694505,0.000052777763,0.0000064160913,0.000088378656,0.00010254526,0.000006453668],"category_scores_gemma":[0.0000214953,0.000094208604,0.000055575434,0.000036935973,0.00017340289,0.0000015324051,0.000044175285,0.00008619167,5.211594e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049505416,0.000032023156,0.0016895335,0.0000284224,0.000070136186,0.0000051372613,0.0003005555,0.000036174988,0.99509126,0.0000014327103,0.0014159405,0.0012798874],"study_design_scores_gemma":[0.0004921051,0.0005210572,0.004247835,0.00005190189,0.000029672054,0.00036547633,0.00008001706,0.000044729837,0.9933508,0.0000013651935,0.0006698131,0.00014523944],"about_ca_topic_score_codex":0.00003380585,"about_ca_topic_score_gemma":0.00000891492,"teacher_disagreement_score":0.0025583012,"about_ca_system_score_codex":0.0000075946214,"about_ca_system_score_gemma":0.000009013076,"threshold_uncertainty_score":0.38417152},"labels":[],"label_agreement":null},{"id":"W4255082801","doi":"10.17504/protocols.io.x39fqr6","title":"Tranfection of sgRNA using SpCas9 containing plasmids to generate cell lines with Cas9 v3","year":2019,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"Cas9; Electroporation; Ribonucleoprotein; Subgenomic mRNA; Plasmid; Nuclease; CRISPR; Transfection; Genome editing; Guide RNA; Biology; Computational biology; Molecular biology; Cell culture; Cell biology; RNA; Chemistry; Genetics; DNA; Gene","score_opus":0.013237326227648309,"score_gpt":0.2949913527984972,"score_spread":0.2817540265708489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255082801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78041744,0.00040277487,0.2175496,0.000013467601,0.00037089427,0.00028891125,0.000022261942,0.000020899884,0.000913775],"genre_scores_gemma":[0.98513824,0.00008396004,0.013664811,0.00005281436,0.00032533085,0.000013085724,0.00007945347,0.00006689014,0.0005754296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889094,0.000022313427,0.00027100733,0.00046908436,0.00012071226,0.0002259423],"domain_scores_gemma":[0.9992667,0.0000073261403,0.00009986914,0.0004071635,0.00013619638,0.000082760256],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000114030714,0.0002794883,0.00030717868,0.00008762796,0.00002775475,0.000025318077,0.00014070836,0.00029042386,0.000012737998],"category_scores_gemma":[0.000010137744,0.00025116396,0.000107626656,0.000064327316,0.00002039602,0.0000014145049,0.00019542898,0.00016555008,0.0000033644176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008028336,0.000018165938,0.0007604331,0.00015322753,0.000059461512,0.0000017828356,0.000055052,0.40529183,0.59325534,0.0000027748956,0.00006208897,0.00025954086],"study_design_scores_gemma":[0.00043875256,0.00046865185,0.0002704208,0.0000947061,0.00007852586,0.00001964189,0.000081541904,0.011569269,0.98525065,0.0000027863957,0.0013609808,0.0003640512],"about_ca_topic_score_codex":0.00023258256,"about_ca_topic_score_gemma":0.00012428006,"teacher_disagreement_score":0.39372256,"about_ca_system_score_codex":0.00001877553,"about_ca_system_score_gemma":0.00012972744,"threshold_uncertainty_score":0.99999404},"labels":[],"label_agreement":null},{"id":"W4255365098","doi":"10.3410/f.717969062.793517055","title":"Faculty Opinions recommendation of Multiplex genome engineering using CRISPR/Cas systems.","year":2016,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"CRISPR; Multiplex; Computational biology; Genome engineering; Genome; Multiplex polymerase chain reaction; Computer science; Biology; Data science; Genetics; Genome editing; Gene; Polymerase chain reaction","score_opus":0.02505420986849337,"score_gpt":0.364837083281268,"score_spread":0.33978287341277463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255365098","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000034825416,0.0038688271,0.0037126453,0.011109295,0.0012063185,0.00097381143,0.9790941,0.000020843283,0.000010698066],"genre_scores_gemma":[0.00008884948,0.00057088037,0.0009066145,0.00043549028,0.00064469775,0.00011112291,0.9968474,0.00004255915,0.0003523705],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969183,0.00016156788,0.0012274159,0.00061604625,0.0007070965,0.00036953276],"domain_scores_gemma":[0.9949214,0.00004364144,0.0008046272,0.0013216515,0.002675527,0.00023318808],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007490187,0.0005013733,0.0007024706,0.00024109546,0.000117235155,0.00007395529,0.0010665794,0.00071222597,0.00007189573],"category_scores_gemma":[0.0029323502,0.00033824626,0.0004968192,0.0006635595,0.00012712454,0.00002547043,0.0004919407,0.000450239,0.000010043274],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000074299733,0.00008889795,0.00000312658,0.0058199544,0.00016613095,1.8303176e-7,0.000023009183,0.000021950449,0.0011257896,0.000021203596,0.9924445,0.00027779222],"study_design_scores_gemma":[0.00046489056,0.000082350205,0.00041595963,0.0053943126,0.00012673363,0.000049681377,0.0000120799,0.00009785153,0.00066700834,8.042008e-7,0.9923202,0.0003681699],"about_ca_topic_score_codex":0.00004308094,"about_ca_topic_score_gemma":0.000002457932,"teacher_disagreement_score":0.017753337,"about_ca_system_score_codex":0.00007849224,"about_ca_system_score_gemma":0.00026561023,"threshold_uncertainty_score":0.99990696},"labels":[],"label_agreement":null},{"id":"W4255755555","doi":"10.32920/ryerson.14643987","title":"In defense of traditional knowledge: the case of Bt brinjal and challenges to the international intellectual property agenda","year":2021,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University; York University","funders":"","keywords":"Lawsuit; Intellectual property; Tamil; Harmonization; Traditional knowledge; Treaty; Agriculture; Political science; Newspaper; Law; Jurisprudence; Geography; Biology; Indigenous","score_opus":0.05539790097905002,"score_gpt":0.309563482783608,"score_spread":0.254165581804558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255755555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97767735,0.012519504,0.0023843877,0.0024659834,0.00045272734,0.0002981942,0.00006559578,0.0000030442638,0.0041332357],"genre_scores_gemma":[0.99662876,0.0022726508,0.00036656935,0.000075467025,0.00018280203,0.000030012972,0.00003516507,0.000010001066,0.0003985595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993346,0.000045759254,0.00021655828,0.0002487627,0.00006857155,0.00008576173],"domain_scores_gemma":[0.99951625,0.000060749702,0.000037250345,0.00025800383,0.00010227031,0.000025458337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022654855,0.000118942306,0.0001386603,0.000040789695,0.000016866563,0.0000127183885,0.00021871325,0.000104453895,0.0000631238],"category_scores_gemma":[0.00018169917,0.00006564377,0.000071674105,0.000034145753,0.000056000674,0.0000010485733,0.0005583107,0.00014821693,5.6582945e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010595316,0.0025690391,0.0005160615,0.003671052,0.0032527354,0.00072491873,0.12010549,0.04786177,0.47659498,0.006302152,0.054667175,0.2826751],"study_design_scores_gemma":[0.0016524317,0.0008344792,0.0032901072,0.0005144461,0.00015925197,0.004054792,0.023691025,0.009303934,0.77689266,0.00043780456,0.17804594,0.0011231301],"about_ca_topic_score_codex":0.0001411013,"about_ca_topic_score_gemma":0.002175324,"teacher_disagreement_score":0.30029768,"about_ca_system_score_codex":0.000008220105,"about_ca_system_score_gemma":0.0000946053,"threshold_uncertainty_score":0.26768753},"labels":[],"label_agreement":null},{"id":"W4256092138","doi":"10.3410/f.718538751.793499318","title":"Faculty Opinions recommendation of Selection of chromosomal DNA libraries using a multiplex CRISPR system.","year":2014,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Multiplex; Selection (genetic algorithm); Computational biology; DNA; Computer science; Biology; Genetics; Gene; Artificial intelligence","score_opus":0.021582904827595208,"score_gpt":0.3515645519239555,"score_spread":0.3299816470963603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256092138","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000018650471,0.0011046941,0.001708991,0.006176238,0.000696997,0.0008224617,0.98943245,0.000019469426,0.000020056634],"genre_scores_gemma":[0.0005757341,0.00014408775,0.0020361228,0.00033824582,0.00043305915,0.00007255189,0.99623835,0.000029692534,0.00013213999],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970075,0.00028496791,0.0012715408,0.00051802234,0.00065583707,0.0002621438],"domain_scores_gemma":[0.9949653,0.000042054548,0.0011596046,0.0009199323,0.002758134,0.00015494069],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065199274,0.00040808597,0.000738017,0.0002140664,0.0001319975,0.00005515214,0.0008255141,0.0007013712,0.00007626887],"category_scores_gemma":[0.0023430742,0.00030009722,0.00048780732,0.00086295087,0.00021280354,0.000029597792,0.0003683911,0.00040230292,0.0000036392626],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016646047,0.00013166347,0.00001119438,0.011313283,0.00015493188,5.0706657e-8,0.00003232658,0.000005834439,0.0010932919,0.00005845797,0.986765,0.00041731854],"study_design_scores_gemma":[0.00046484693,0.00017587752,0.00046813884,0.006119784,0.0001737588,0.000043860437,0.000028793933,0.00017567148,0.006872296,0.0000017386416,0.98520786,0.0002673844],"about_ca_topic_score_codex":0.00005595256,"about_ca_topic_score_gemma":0.0000066229272,"teacher_disagreement_score":0.006805924,"about_ca_system_score_codex":0.000045750374,"about_ca_system_score_gemma":0.00035908492,"threshold_uncertainty_score":0.9999451},"labels":[],"label_agreement":null},{"id":"W4256102309","doi":"10.3410/f.737316694.793574115","title":"Faculty Opinions recommendation of Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Japan Society for the Promotion of Science; National Institute of Child Health and Human Development; Natural Sciences and Engineering Research Council of Canada; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of British Columbia; National Natural Science Foundation of China; National Institute of Mental Health; Fudan University; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Max-Planck-Gesellschaft; Deutsche Forschungsgemeinschaft; Simons Foundation Autism Research Initiative; Howard Hughes Medical Institute; Ministry of Education, Culture, Sports, Science and Technology; Canadian Institutes of Health Research; National Science Foundation","keywords":"Germline; Recombination; Nervous system; Gene; Genetics; Biology; Computational biology; Neuroscience","score_opus":0.015791814710234456,"score_gpt":0.31409250136655464,"score_spread":0.2983006866563202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256102309","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014498467,0.0033867662,0.0009620424,0.005644979,0.00029386475,0.00080543716,0.9887398,0.000016916882,0.0000052263767],"genre_scores_gemma":[0.0010591813,0.0014624781,0.003591002,0.00019061676,0.0001860847,0.00005255601,0.993374,0.000026219126,0.000057891142],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973521,0.00017781397,0.001123257,0.0005603928,0.00057884655,0.00020759499],"domain_scores_gemma":[0.9952816,0.00004567769,0.0011293987,0.0006484134,0.0027351899,0.0001597598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054524164,0.0003831024,0.0006158053,0.00015150095,0.00011348152,0.00004726682,0.0006084651,0.00042309548,0.00001883539],"category_scores_gemma":[0.001395181,0.00026216256,0.00022739956,0.0006639713,0.00015864539,0.000032891607,0.0003290529,0.00040687743,0.0000011880475],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017904591,0.000078984,0.00003693584,0.018021151,0.000114401504,1.7882026e-7,0.00015629869,0.00001700556,0.0013254997,0.000015533333,0.97971874,0.00049736106],"study_design_scores_gemma":[0.00046431136,0.00022445476,0.0017318431,0.0077940025,0.0001448603,0.000022035161,0.00009094476,0.000054119977,0.003071137,7.471722e-7,0.9861285,0.00027303913],"about_ca_topic_score_codex":0.000016694574,"about_ca_topic_score_gemma":0.0000012517854,"teacher_disagreement_score":0.010227148,"about_ca_system_score_codex":0.000045093213,"about_ca_system_score_gemma":0.00017253429,"threshold_uncertainty_score":0.9999831},"labels":[],"label_agreement":null},{"id":"W4256643088","doi":"10.1016/j.nmd.2020.08.220","title":"DMD – ANIMAL MODELS &amp; PRECLINICAL TREATMENT","year":2020,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Gene duplication; CRISPR; Cas9; Tandem exon duplication; Guide RNA; Genome editing; Biology; Phenotype; Gene; Genetics; Computational biology; Mutation; Bioinformatics","score_opus":0.032913007739687014,"score_gpt":0.3222993331744531,"score_spread":0.28938632543476606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256643088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95845675,0.0016242819,0.036162704,0.0016215399,0.000119144825,0.00028173314,0.00001350359,0.00005957418,0.0016607684],"genre_scores_gemma":[0.9972175,0.0009457694,0.00080615474,0.0005829842,0.00018765447,0.000024634874,0.000074064985,0.000039529798,0.000121750374],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990228,0.000037068156,0.00016431537,0.00043638083,0.00011243852,0.00022702226],"domain_scores_gemma":[0.999493,0.000008090123,0.000024626292,0.00029734502,0.000016188586,0.00016073798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003414708,0.00018022188,0.00014341917,0.000014668553,0.000043669366,0.000017812496,0.00014787201,0.00009665032,0.000028461218],"category_scores_gemma":[0.000051862542,0.00017350598,0.00020151478,0.00006984782,0.0000355303,0.0000030433514,0.00007165361,0.00007131831,0.00003026868],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036184795,0.00036875336,0.0034427743,0.00006471292,0.00026700017,0.000009688546,0.00048616735,0.06634846,0.8944168,0.00017506948,0.00325283,0.030805852],"study_design_scores_gemma":[0.003931016,0.005485732,0.006928177,0.000011709102,0.00017966576,0.000016290742,0.00011262661,0.017833814,0.06378944,0.00026968255,0.9003113,0.001130562],"about_ca_topic_score_codex":0.000010665708,"about_ca_topic_score_gemma":0.000038853286,"teacher_disagreement_score":0.8970584,"about_ca_system_score_codex":0.0000050003327,"about_ca_system_score_gemma":0.000027575874,"threshold_uncertainty_score":0.7075368},"labels":[],"label_agreement":null},{"id":"W4280493960","doi":"10.1186/s12896-022-00744-8","title":"Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci","year":2022,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"University of California, Irvine; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada; European Genomic Institute for Diabetes","keywords":"Biology; Cre-Lox recombination; Electroporation; Allele; Genetics; Genome; Computational biology; Simple (philosophy); Gene; Transgene","score_opus":0.014087840429801409,"score_gpt":0.26429645503511995,"score_spread":0.2502086146053185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280493960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60159594,0.00047092672,0.39712152,0.00040525978,0.0000011981952,0.0003183133,0.0000727109,0.000008678921,0.000005460916],"genre_scores_gemma":[0.8338267,0.00002597365,0.0075595747,0.00005072075,0.000113687405,0.0001474881,0.15824962,0.000008674823,0.000017513183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993011,0.000055881013,0.00019840729,0.00022868505,0.000068389025,0.00014754571],"domain_scores_gemma":[0.9997587,0.0000026630012,0.000062824845,0.00014690036,0.000022029659,0.0000068681425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027659573,0.00007599694,0.00009362074,0.000082592866,0.00006589141,0.0000051369634,0.00013283649,0.000111478184,0.000045897545],"category_scores_gemma":[0.00004704637,0.00007610844,0.000030278215,0.00016558552,0.000040800227,0.000002519149,0.000049404167,0.00011353102,2.121256e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026074718,0.000071626884,0.00025943888,0.000011825609,0.0000054384977,7.521145e-8,0.000028149725,0.047476836,0.8440526,0.00054715463,0.10746384,0.00005691631],"study_design_scores_gemma":[0.00051744265,0.0003589322,0.00034891153,1.1247775e-8,0.0000050407893,0.0000075309727,0.0006522046,0.044702213,0.7280368,0.00014615672,0.2251039,0.00012081856],"about_ca_topic_score_codex":0.000014700198,"about_ca_topic_score_gemma":0.00008431188,"teacher_disagreement_score":0.38956195,"about_ca_system_score_codex":0.000027314962,"about_ca_system_score_gemma":0.000014567292,"threshold_uncertainty_score":0.3103612},"labels":[],"label_agreement":null},{"id":"W4280509090","doi":"10.1038/s41467-022-30310-x","title":"A truncated anti-CRISPR protein prevents spacer acquisition but not interference","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"French Infrastructure for Integrated Structural Biology; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Agence Nationale de la Recherche","keywords":"CRISPR; Cas9; CRISPR interference; Biology; Gene; DNA; Acquired immune system; Genetics; Nucleic acid; Mutant; Computational biology; Immune system","score_opus":0.011781806655911744,"score_gpt":0.31679136886261294,"score_spread":0.3050095622067012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280509090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98586136,0.0052016843,0.0047124983,0.0021129048,0.00020494731,0.0005432132,0.00013671188,0.000053892425,0.001172781],"genre_scores_gemma":[0.9956864,0.00013664969,0.0022046994,0.0003077532,0.00004339556,0.00021407029,0.00055559987,0.000018333896,0.0008331146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930376,0.000110228764,0.00013653823,0.00019532854,0.0001133681,0.00014075193],"domain_scores_gemma":[0.99869907,0.000010695324,0.000052692678,0.001136667,0.000060207145,0.000040694435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013941477,0.00010371155,0.00008414596,0.000048711277,0.00025970617,0.00001780316,0.0006484034,0.00011707579,0.00005392558],"category_scores_gemma":[0.000045339857,0.00011467337,0.000059516035,0.00014745817,0.00003900188,0.000003173449,0.0007903131,0.0004941388,0.0000055937244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024456282,0.00010770664,0.00035309242,0.0000072220237,0.0000328796,5.374495e-7,0.00007358872,0.00024623508,0.9957977,0.0003497224,0.0023445557,0.0006623063],"study_design_scores_gemma":[0.0006675009,0.00024773317,0.0119679365,0.00002577678,0.000036617887,0.000034276407,0.00030128058,0.0014294343,0.80242956,0.00008559508,0.18238263,0.0003916427],"about_ca_topic_score_codex":0.00001419684,"about_ca_topic_score_gemma":0.000032592918,"teacher_disagreement_score":0.1933681,"about_ca_system_score_codex":0.000026777045,"about_ca_system_score_gemma":0.000043608426,"threshold_uncertainty_score":0.46762443},"labels":[],"label_agreement":null},{"id":"W4280554122","doi":"10.12688/f1000research.110194.1","title":"The third international hackathon for applying insights into large-scale genomic composition to use cases in a wide range of organisms","year":2022,"lang":"en","type":"preprint","venue":"F1000Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Roche (Canada)","funders":"U.S. National Library of Medicine; NIHR Maudsley Biomedical Research Centre; Agricultural Research Service; Centers for Disease Control and Prevention; China Scholarship Council; Fonds Wetenschappelijk Onderzoek; Oxford Nanopore Technologies; Motor Neurone Disease Association; Large Facilities Office; National Institute for Health and Care Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Association of Public Health Laboratories; Norges Forskningsråd; U.S. Department of Agriculture; National Science Foundation","keywords":"Genotyping; Computational biology; Genomics; Data science; Bioinformatics; Biology; Medicine; Computer science; Genetics; Genome; Gene; Genotype","score_opus":0.023257780782020197,"score_gpt":0.3536213010709212,"score_spread":0.33036352028890104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280554122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9637699,0.001552479,0.0323465,0.00027447092,0.00038060112,0.001418575,0.00016185112,0.00001043269,0.00008519612],"genre_scores_gemma":[0.9925726,0.00082360854,0.0044333925,0.000068990325,0.00015645019,0.00096094405,0.0005887242,0.000043942135,0.00035137153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868995,0.0000922642,0.00028140435,0.00039302433,0.00028198192,0.00026135126],"domain_scores_gemma":[0.99907875,0.000216441,0.000055093355,0.0004343545,0.00014967346,0.00006570165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051302783,0.0001461234,0.00016553586,0.00015573303,0.0001394889,0.000070114314,0.0005672552,0.00013154696,0.00001914188],"category_scores_gemma":[0.0002735013,0.00013504887,0.00009725291,0.00009730591,0.000040499654,0.000003129116,0.0016111563,0.00029066033,0.0000023424136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055402686,0.00011540311,0.010519412,0.00017713847,0.000103352184,0.000013519719,0.0015876255,0.013619528,0.96973664,0.00011417084,0.001955322,0.0015038829],"study_design_scores_gemma":[0.0022472956,0.0007361759,0.06251995,0.00021326305,0.000050047183,0.000020517215,0.0020705382,0.009498471,0.57387125,0.00096944376,0.3469518,0.00085124146],"about_ca_topic_score_codex":0.00021800367,"about_ca_topic_score_gemma":0.0011151624,"teacher_disagreement_score":0.39586535,"about_ca_system_score_codex":0.00009823211,"about_ca_system_score_gemma":0.00012417126,"threshold_uncertainty_score":0.5507133},"labels":[],"label_agreement":null},{"id":"W4280594278","doi":"10.3390/ijms23105597","title":"A CRISPR/Cas9-Based System with Controllable Auto-Excision Feature Serving Cisgenic Plant Breeding and Beyond","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Feature (linguistics); Biology; Cas9; Computer science; Genetics; Biotechnology; Gene","score_opus":0.0055698868992993,"score_gpt":0.2615956369954096,"score_spread":0.2560257500961103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280594278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9295482,0.0034687596,0.06498701,0.000981776,0.00053065695,0.000077794764,0.000020916039,0.000006558916,0.00037830128],"genre_scores_gemma":[0.99604505,0.000022942046,0.003502154,0.00027888044,0.000103175815,0.0000038044307,0.0000059902973,0.000008164669,0.000029856943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886924,0.000041377283,0.00017335659,0.0001755269,0.0006070107,0.00013350531],"domain_scores_gemma":[0.999523,0.000018808278,0.00015965356,0.00007507888,0.00016101297,0.00006243759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000512345,0.00009532633,0.00011481131,0.0001417537,0.00014448626,0.00008975407,0.00041056192,0.000029123394,0.000008165486],"category_scores_gemma":[0.000029566894,0.000076548815,0.0000606387,0.000110131754,0.00005327916,0.0000098401815,0.00013329847,0.00011851363,1.9160201e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025138684,0.000032052427,0.001673734,0.000015036295,0.00012873705,0.00027329428,0.00009653239,0.10443798,0.89102286,0.000272584,0.00045453972,0.001341247],"study_design_scores_gemma":[0.00874069,0.007617006,0.0036719476,0.00043510247,0.00019226837,0.013480268,0.008028471,0.18933557,0.73295295,0.00015848053,0.034266397,0.0011208333],"about_ca_topic_score_codex":0.000008060219,"about_ca_topic_score_gemma":0.0000049131854,"teacher_disagreement_score":0.15806991,"about_ca_system_score_codex":0.00003493596,"about_ca_system_score_gemma":0.00013859915,"threshold_uncertainty_score":0.31215703},"labels":[],"label_agreement":null},{"id":"W4281253995","doi":"10.1021/acs.molpharmaceut.1c00916","title":"Lipid-Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Components","year":2022,"lang":"en","type":"review","venue":"Molecular Pharmaceutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":292,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Huntington Society of Canada","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Flexibility (engineering); Genome; Computer science; Biology; Gene; Genetics","score_opus":0.061957392736683284,"score_gpt":0.38517399350163606,"score_spread":0.3232166007649528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281253995","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0029327266,0.98975664,0.0058073504,0.000010782394,0.000514132,0.0005795508,0.00018946642,0.000030443687,0.0001789099],"genre_scores_gemma":[0.010458754,0.98680216,0.0007864,0.00018761528,0.0002817881,0.000107819185,0.0011592782,0.00016482486,0.00005134888],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99760777,0.00023336656,0.0007104016,0.00057776435,0.00037923575,0.0004914861],"domain_scores_gemma":[0.99871194,0.00003998605,0.00032498848,0.0006714052,0.00006870408,0.00018295119],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003078416,0.0005108759,0.0008558349,0.00016188186,0.00009696028,0.000023909717,0.0005766442,0.0002456919,0.00013910812],"category_scores_gemma":[0.00005345264,0.0005634309,0.0006503509,0.00028277544,0.00007664201,0.0000022930933,0.0004320396,0.00041182432,0.000011915593],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045061217,0.0004021226,0.000021214557,0.015021862,0.0010080652,0.00018153335,0.00004131777,0.008642422,0.54673094,0.000015282794,0.00038632107,0.42750388],"study_design_scores_gemma":[0.0004266981,0.00010001506,0.0000010670143,0.00029900885,0.0007237733,0.00003020358,0.00001035243,0.00051356916,0.12797792,8.221291e-7,0.8694778,0.0004387363],"about_ca_topic_score_codex":0.000005615144,"about_ca_topic_score_gemma":7.588907e-7,"teacher_disagreement_score":0.8690915,"about_ca_system_score_codex":0.00006163764,"about_ca_system_score_gemma":0.00020925925,"threshold_uncertainty_score":0.9996817},"labels":[],"label_agreement":null},{"id":"W4281255417","doi":"10.1016/j.gene.2022.146556","title":"Understanding of the various aspects of gene regulatory networks related to crop improvement","year":2022,"lang":"en","type":"review","venue":"Gene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University","funders":"Fonds de recherche du Québec – Nature et technologies","keywords":"Biology; Gene regulatory network; Computational biology; Transcriptome; Gene; Biotechnology; Systems biology; Genetics; Gene expression","score_opus":0.029716291481870088,"score_gpt":0.2966469831955794,"score_spread":0.2669306917137093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281255417","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005395681,0.98632,0.011175586,0.000006539347,0.0006483106,0.0005837316,0.000042599,0.000007416905,0.0006762205],"genre_scores_gemma":[0.020965176,0.9780188,0.00029510047,0.000026753316,0.000113271155,0.000046018817,0.000119161,0.00006755527,0.00034817078],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99867576,0.000059574257,0.0005028967,0.00034370238,0.0001895169,0.0002285707],"domain_scores_gemma":[0.9988795,0.0000143648695,0.00025508172,0.00076706946,0.000023913972,0.000060068498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023487721,0.00024266928,0.0005446359,0.00006441248,0.00006425483,0.000005625116,0.00038956184,0.00021823437,0.00004004911],"category_scores_gemma":[0.000025214713,0.00019701936,0.00036501297,0.00026993413,0.000040089828,5.960753e-7,0.00036810912,0.00017780859,6.4934414e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041706695,0.00018471047,0.000010216512,0.0060339393,0.0021118876,0.00001634799,0.00022481084,0.06693653,0.25529614,0.0010647549,0.0023687845,0.66571015],"study_design_scores_gemma":[0.00039110798,0.0005513941,0.00002496329,0.0009868864,0.0007524561,0.00006329115,0.00005049872,0.000102820995,0.094465666,0.00010624071,0.90186095,0.0006437046],"about_ca_topic_score_codex":0.000008074455,"about_ca_topic_score_gemma":0.0000047323542,"teacher_disagreement_score":0.8994922,"about_ca_system_score_codex":0.00009929388,"about_ca_system_score_gemma":0.00015933406,"threshold_uncertainty_score":0.8034216},"labels":[],"label_agreement":null},{"id":"W4281289922","doi":"10.1101/2022.05.20.492479","title":"CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Danish Agency for Science and Higher Education; Canadian Institutes of Health Research; Danmarks Frie Forskningsfond","keywords":"CRISPR; Biology; Virulence; Plasmid; Microbiology; Bacteria; In vivo; In vitro; DNA; Multiplicity of infection; Nucleic acid; Gene; Genetics","score_opus":0.010795196595506932,"score_gpt":0.26101470208023486,"score_spread":0.25021950548472793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281289922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906615,0.0027680227,0.0033588593,0.00018615134,0.0010567323,0.0015322235,0.00029784767,0.00012342955,0.0000152358],"genre_scores_gemma":[0.99480265,0.000384154,0.0032887082,0.00032475987,0.0003669213,0.0006197903,0.000006243498,0.00017222654,0.00003457034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968186,0.00023534318,0.00064249366,0.0012524489,0.000314814,0.00073632033],"domain_scores_gemma":[0.9975109,0.000030920095,0.00020707528,0.0017313339,0.00021517953,0.00030457307],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065599626,0.0006674412,0.0005437712,0.00034845227,0.00013087383,0.00014280883,0.000940149,0.00048792668,0.000095465315],"category_scores_gemma":[0.0003733613,0.0008082419,0.00021390947,0.0004741541,0.000056874593,0.0000091164775,0.0019023312,0.0008743674,0.000024909956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009257841,0.00022401406,0.004462424,0.0005664158,0.00011237436,0.00004368601,0.000032904223,0.0019450862,0.9921321,0.0000076205515,0.00037619603,0.000004594307],"study_design_scores_gemma":[0.0005709385,0.00022342529,0.17812902,0.00021839673,0.00008056842,8.538685e-8,0.000015057721,0.00025386378,0.8023317,3.5047748e-7,0.0172023,0.0009743265],"about_ca_topic_score_codex":0.00014614544,"about_ca_topic_score_gemma":0.000023921795,"teacher_disagreement_score":0.18980044,"about_ca_system_score_codex":0.0002651793,"about_ca_system_score_gemma":0.00041998748,"threshold_uncertainty_score":0.99943686},"labels":[],"label_agreement":null},{"id":"W4281567315","doi":"10.3390/cells11111729","title":"Large-Scale Analysis of X Inactivation Variations between Primed and Naïve Human Embryonic Stem Cells","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust","keywords":"XIST; X-inactivation; X chromosome; Dosage compensation; Embryonic stem cell; Biology; Chromosome; Molecular biology; Genetics; Gene; Cell biology","score_opus":0.007580872040930333,"score_gpt":0.26774262214267625,"score_spread":0.2601617501017459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281567315","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738063,0.00015502996,0.025676135,0.000015418755,0.00004500419,0.00009586699,0.00008301422,0.000006161429,0.00011705422],"genre_scores_gemma":[0.99918246,0.000010379638,0.00029139846,0.000014260722,0.000031946813,0.000012725428,0.0001463814,0.000008562529,0.00030189005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945974,0.00003506921,0.00013489385,0.0001792215,0.000082773266,0.00010832792],"domain_scores_gemma":[0.99966705,0.000011596015,0.000063675965,0.00019733688,0.000026204656,0.000034140005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013551221,0.00006835338,0.00013051674,0.00009469401,0.000086308275,0.0000074511854,0.00007966495,0.000041512954,0.000034074223],"category_scores_gemma":[0.0000017682585,0.00007903251,0.00006419158,0.00021745276,0.000013131884,0.0000014919068,0.00014934817,0.000061024166,4.0755413e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000030576737,0.000030198986,0.0045592855,0.000011593549,0.00020718452,1.6020925e-7,0.0002762807,0.008364141,0.9863053,0.000028487375,0.00005917926,0.00015513563],"study_design_scores_gemma":[0.00020684542,0.0000805553,0.022099372,0.0000012063749,0.00026701234,1.735084e-7,0.0003033496,0.0015592261,0.9740256,0.0000145400345,0.001347379,0.00009472236],"about_ca_topic_score_codex":0.000009200645,"about_ca_topic_score_gemma":0.000009329496,"teacher_disagreement_score":0.025384735,"about_ca_system_score_codex":0.0000136481,"about_ca_system_score_gemma":0.000016994682,"threshold_uncertainty_score":0.3222852},"labels":[],"label_agreement":null},{"id":"W4281618698","doi":"10.1038/s41375-022-01602-4","title":"Elucidating the importance and regulation of key enhancers for human MEIS1 expression","year":2022,"lang":"en","type":"article","venue":"Leukemia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Terry Fox Research Institute","funders":"Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada; Michael Smith Health Research BC; Government of Canada; Terry Fox Foundation; Genome British Columbia","keywords":"Transcription factor; Enhancer; Biology; Myeloid leukemia; In silico; Cancer research; Locus (genetics); Transcriptional regulation; Regulation of gene expression; Regulator; Genetics; Gene; Cell biology","score_opus":0.007532661366015999,"score_gpt":0.28413893954524005,"score_spread":0.27660627817922406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281618698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98433274,0.00059931417,0.014592792,0.000029133114,0.000046458692,0.00012539886,0.000007799674,0.0000041172825,0.00026223424],"genre_scores_gemma":[0.99853134,0.00001252335,0.00094574085,0.000040531482,0.00006805117,0.00004833555,0.00005050522,0.000008100268,0.0002948458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996501,0.000011586778,0.000097522294,0.00011520735,0.00005436338,0.00007119476],"domain_scores_gemma":[0.9997726,0.0000088937195,0.000051749594,0.000141031,0.000013538347,0.000012200201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011903407,0.000045218832,0.00004756035,0.0000090171,0.00012945202,0.0000038994863,0.00006668124,0.000021671965,0.000013871172],"category_scores_gemma":[0.000017128363,0.000038438135,0.000024500563,0.000025760535,0.000017364007,0.0000010773575,0.000072894654,0.000035733654,4.3061632e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012636545,0.0000019349686,0.00048426725,0.0000142174285,0.0000048937054,4.647558e-8,0.00009609309,0.003204204,0.9945904,0.00015570835,0.00059185695,0.0008437542],"study_design_scores_gemma":[0.0002281763,0.000081794846,0.0031411636,0.0000049609694,0.000005965094,0.000002178087,0.00015493251,0.00075649534,0.9837445,0.00017609909,0.011647399,0.00005632708],"about_ca_topic_score_codex":0.0000069664684,"about_ca_topic_score_gemma":0.000007195658,"teacher_disagreement_score":0.014198614,"about_ca_system_score_codex":0.000016000746,"about_ca_system_score_gemma":0.000021285941,"threshold_uncertainty_score":0.15674616},"labels":[],"label_agreement":null},{"id":"W4281623662","doi":"10.3390/ijms23116160","title":"Prime Editing Permits the Introduction of Specific Mutations in the Gene Responsible for Duchenne Muscular Dystrophy","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Centre Hospitalier Universitaire de Québec","keywords":"Duchenne muscular dystrophy; Exon; Point mutation; Dystrophin; Exon skipping; Molecular biology; Biology; Gene; Genetics; Mutation; Alternative splicing","score_opus":0.01106526513810114,"score_gpt":0.3053127387184403,"score_spread":0.29424747358033915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281623662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96078,0.0013665197,0.03303219,0.003987096,0.00067879265,0.00010494168,0.000010679744,8.7822485e-7,0.00003885701],"genre_scores_gemma":[0.99574053,0.000041900308,0.0035060423,0.00008235187,0.0005888776,0.000012137868,0.000010224213,0.000004275493,0.000013674943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990313,0.00009677652,0.00024256844,0.00011183708,0.00042824668,0.00008927477],"domain_scores_gemma":[0.99948794,0.000035542576,0.0001636218,0.00010106445,0.00019891765,0.000012928707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012660729,0.000052511503,0.00006157223,0.000116976225,0.00011134565,0.000031067455,0.0006001341,0.000014538471,0.0000101088535],"category_scores_gemma":[0.00017072256,0.000035998095,0.00009828668,0.00017033704,0.00009554104,0.000007670587,0.00006796234,0.0000916251,1.1955694e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004328258,0.00003661019,0.0000989227,0.0000014664503,0.000029938492,0.00000849823,0.0002855562,0.08241113,0.91454184,0.00068401714,0.00029226806,0.0015664863],"study_design_scores_gemma":[0.00063103065,0.00064405525,0.0025604584,0.000008449958,0.000022440774,0.0005952653,0.0032773728,0.0011522995,0.94953066,0.0009137626,0.040560808,0.000103415856],"about_ca_topic_score_codex":0.0000041285307,"about_ca_topic_score_gemma":0.000002198136,"teacher_disagreement_score":0.08125883,"about_ca_system_score_codex":0.000018716713,"about_ca_system_score_gemma":0.00009628475,"threshold_uncertainty_score":0.14679597},"labels":[],"label_agreement":null},{"id":"W4281709393","doi":"10.1016/j.omtm.2022.05.012","title":"Impact of genetically modified organism requirements on gene therapy development in the EU, Japan, and the US","year":2022,"lang":"en","type":"review","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"CMC Microsystems","keywords":"Genetically modified organism; Timeline; Biotechnology; Genetically engineered; Organism; Risk analysis (engineering); Business; Biology; Computational biology; Gene; Genetics; Geography","score_opus":0.14046264139612583,"score_gpt":0.5092570239269937,"score_spread":0.3687943825308678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281709393","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04210184,0.9364321,0.018583238,0.000057301466,0.00028556297,0.0023232868,0.000008866585,0.000013281647,0.00019450622],"genre_scores_gemma":[0.0017924254,0.9409237,0.055486437,0.00076384796,0.000083815205,0.00062569685,0.00015946559,0.0001154853,0.000049120845],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9921094,0.0037084164,0.0020372188,0.0009944286,0.0005997699,0.00055076054],"domain_scores_gemma":[0.9974456,0.00069745124,0.0005028666,0.0011444929,0.00007030741,0.0001392939],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007682661,0.0007823353,0.0016251131,0.00014526786,0.00017649173,0.000055162232,0.001189969,0.00045730406,0.000064390486],"category_scores_gemma":[0.00037379793,0.0004369819,0.0007910107,0.00037072002,0.0002575351,0.0000025188428,0.0004112794,0.0007219062,0.0000038060912],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024006893,0.00033137065,0.000034299555,0.00013611464,0.0012510037,0.000009542728,0.00036225969,0.000097817065,0.0016405169,0.000049761806,0.000023202385,0.99582404],"study_design_scores_gemma":[0.0031703538,0.0007867962,0.0019988,0.00023897299,0.0001019465,0.000028837429,0.000016537973,0.000014313978,0.006571052,0.000064626074,0.9863254,0.0006823684],"about_ca_topic_score_codex":0.000011569392,"about_ca_topic_score_gemma":0.000002426521,"teacher_disagreement_score":0.9951417,"about_ca_system_score_codex":0.000097171454,"about_ca_system_score_gemma":0.0009466857,"threshold_uncertainty_score":0.9998082},"labels":[],"label_agreement":null},{"id":"W4281713899","doi":"10.1016/j.ajhg.2022.05.004","title":"Comprehensive evaluation and efficient classification of BRCA1 RING domain missense substitutions","year":2022,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; Canadian Institutes of Health Research; School of Medicine; National Institutes of Health","keywords":"Missense mutation; Biology; Genetics; Computational biology; Population; Point mutation; Gene; Mutation; Medicine","score_opus":0.022427582155880112,"score_gpt":0.33592338663812277,"score_spread":0.3134958044822427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281713899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929521,0.0026613928,0.0040569743,0.00008923366,0.000070338916,0.00010106592,0.0000055361174,0.0000014446103,0.000061927036],"genre_scores_gemma":[0.998915,0.00011096954,0.000841923,0.000031035663,0.00007501203,0.0000039892734,0.0000062390823,0.000008974555,0.000006820807],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999172,0.00015189726,0.0002554343,0.000091322596,0.00023775134,0.00009163563],"domain_scores_gemma":[0.9992546,0.000019473762,0.00031844046,0.00018923059,0.00017985718,0.000038425747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040783526,0.00007127221,0.00012524363,0.000058036836,0.00016873448,0.000007609291,0.00014543768,0.00001032904,0.000008471772],"category_scores_gemma":[0.000016009264,0.000061075945,0.00005518626,0.000102646656,0.00020789835,7.998674e-7,0.000077513876,0.00009801326,1.467842e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041044827,0.000033894023,0.00040294573,0.000005196364,0.000044765904,0.0000011375759,0.00044100342,0.096619174,0.8987943,0.000090837006,0.000041702177,0.0034839872],"study_design_scores_gemma":[0.004055854,0.008083887,0.5040054,0.00006410592,0.00072652363,0.001961109,0.032534197,0.035987888,0.3967854,0.0010373526,0.013923483,0.00083484256],"about_ca_topic_score_codex":0.000004196328,"about_ca_topic_score_gemma":0.0000019095637,"teacher_disagreement_score":0.5036024,"about_ca_system_score_codex":0.000021635626,"about_ca_system_score_gemma":0.00005344548,"threshold_uncertainty_score":0.24906048},"labels":[],"label_agreement":null},{"id":"W4281757975","doi":"10.1038/s41467-022-30598-9","title":"Computationally designed hyperactive Cas9 enzymes","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Australian Research Council; Medical Research Council; Israel Science Foundation; York University","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Gene; Synthetic biology; Biology; Genome engineering; Function (biology); Genome; Genetics; Computer science","score_opus":0.011262987099973242,"score_gpt":0.3313653751702304,"score_spread":0.32010238807025715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281757975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69922745,0.16250224,0.07555281,0.017799726,0.0016399287,0.0018020022,0.0006668468,0.0002917112,0.040517278],"genre_scores_gemma":[0.987161,0.00012404333,0.011201619,0.0005307465,0.000047542813,0.00007604227,0.0005380905,0.000012855497,0.00030809088],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995134,0.000083621686,0.00008907559,0.00012649213,0.00009857651,0.00008886967],"domain_scores_gemma":[0.9991785,0.000051695857,0.00003169177,0.00064034126,0.00006805626,0.000029665433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010187975,0.00006705217,0.000054342498,0.000034820856,0.00033716837,0.000010670143,0.0004976564,0.00006375082,0.00003310892],"category_scores_gemma":[0.00005504432,0.00007717063,0.000044071767,0.00010901852,0.000031201806,0.0000016990369,0.00042536086,0.00033352297,0.0000036302363],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075860684,0.0004279337,0.0027714404,0.000009405293,0.0002371704,0.000003633995,0.00065272424,0.037350915,0.8768061,0.02157603,0.054091327,0.0059975046],"study_design_scores_gemma":[0.00051128183,0.00016962389,0.016533691,0.0000029227594,0.00003090699,0.00007726011,0.00060661446,0.0026167543,0.04618314,0.00020340836,0.9327447,0.00031970846],"about_ca_topic_score_codex":0.0000052087344,"about_ca_topic_score_gemma":0.000037885427,"teacher_disagreement_score":0.87865335,"about_ca_system_score_codex":0.000020062462,"about_ca_system_score_gemma":0.000059179667,"threshold_uncertainty_score":0.3146927},"labels":[],"label_agreement":null},{"id":"W4281961566","doi":"10.3390/ijtm2020017","title":"CRISPR-Based Diagnostics for Point-of-Care Viral Detection","year":2022,"lang":"en","type":"article","venue":"International Journal of Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Point-of-care testing; Point of care; Molecular diagnostics; Computational biology; Computer science; Multiplex; Risk analysis (engineering); Standardization; Nanotechnology; Biochemical engineering; Data science; Biology; Bioinformatics; Medicine; Engineering; Genetics; Immunology; Materials science","score_opus":0.008042945079267658,"score_gpt":0.32577868540371785,"score_spread":0.3177357403244502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281961566","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17667976,0.004123496,0.813346,0.0031264639,0.0022839473,0.00016633725,0.00013819011,0.000003861948,0.00013191257],"genre_scores_gemma":[0.995962,0.000059951384,0.0028125278,0.00018980226,0.00081098627,0.000010564462,0.00012874717,0.000010990191,0.00001443498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990955,0.000021707921,0.00033832964,0.000081260936,0.0003963119,0.00006687168],"domain_scores_gemma":[0.99918056,0.000090226626,0.00015979956,0.000055880297,0.00047775125,0.000035799378],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020208213,0.00006979502,0.00011052048,0.00013391636,0.00003835168,0.0000030314616,0.00018977025,0.000028296066,0.000072296076],"category_scores_gemma":[0.0001734736,0.00006611876,0.00011806117,0.00004099699,0.000034070097,0.0000041143962,0.0000136496365,0.00008604563,1.2029757e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025679034,0.00018009955,0.003518912,0.00008243195,0.00040299117,0.00001591131,0.0006342522,0.17819352,0.76559055,0.00052431884,0.00238083,0.045908306],"study_design_scores_gemma":[0.012177212,0.00751958,0.016552363,0.00017741576,0.00026301565,0.00031852484,0.0011721286,0.007470347,0.76612204,0.0019207571,0.18591766,0.00038895983],"about_ca_topic_score_codex":0.0000032614307,"about_ca_topic_score_gemma":0.0000051748907,"teacher_disagreement_score":0.81928223,"about_ca_system_score_codex":0.000021112339,"about_ca_system_score_gemma":0.00006621059,"threshold_uncertainty_score":0.26962447},"labels":[],"label_agreement":null},{"id":"W4281982005","doi":"10.1101/2022.06.01.494308","title":"ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid cells","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; Institute of Genetics; Japan Society for the Promotion of Science; Kanae Foundation for the Promotion of Medical Science; University of Tokyo; Japan Science and Technology Agency; Kato Memorial Bioscience Foundation; Uehara Memorial Foundation","keywords":"CRISPR; Amplicon; Gene; DNA; Flow cytometry; Biology; Transgene; Genome editing; Endogeny; Ploidy; Computational biology; Molecular biology; Genetics; Polymerase chain reaction","score_opus":0.01384179947717542,"score_gpt":0.2624453337056262,"score_spread":0.2486035342284508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281982005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893843,0.0013565165,0.0050693173,0.00016235761,0.0011111692,0.0018035746,0.0009611536,0.00013994348,0.000011686287],"genre_scores_gemma":[0.99295676,0.00044193512,0.0034259718,0.0010098151,0.0006625685,0.0011486249,0.000015297719,0.00030425182,0.000034778484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99603546,0.00009304613,0.00077265,0.0016839745,0.00037566826,0.0010392263],"domain_scores_gemma":[0.9975768,0.000040537758,0.00021497796,0.001516832,0.00022946685,0.00042140475],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057239126,0.00079901627,0.0007100456,0.0004204098,0.0002700893,0.00016249758,0.00091446226,0.0005994077,0.000120975834],"category_scores_gemma":[0.00017292188,0.0010085289,0.00032347214,0.00040135658,0.00006235233,0.000009265461,0.001177261,0.0006350361,0.00002675172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008638865,0.00012684576,0.0016158905,0.00029816286,0.00015292465,0.00007087733,0.00006597551,0.002455589,0.9948452,0.000013702814,0.00026540473,0.0000030538777],"study_design_scores_gemma":[0.0008824919,0.0002575093,0.0052865986,0.00008969596,0.000081704,1.3733803e-7,0.00001659551,0.00011099265,0.9724718,5.569263e-7,0.019675499,0.0011264458],"about_ca_topic_score_codex":0.00023889805,"about_ca_topic_score_gemma":0.000034661647,"teacher_disagreement_score":0.022373412,"about_ca_system_score_codex":0.0002535854,"about_ca_system_score_gemma":0.00044453927,"threshold_uncertainty_score":0.9992365},"labels":[],"label_agreement":null},{"id":"W4282546094","doi":"10.3389/fbioe.2022.885227","title":"CRISPR/Cas9-Based Deletion of SpvB Gene From Salmonella gallinarum Leads to Loss of Virulence in Chicken","year":2022,"lang":"en","type":"article","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Department of Health and Social Care; International Development Research Centre; National Institute for Health and Care Research; Government of the United Kingdom","keywords":"Virulence; Biology; Plasmid; Microbiology; Virology; Gene; Salmonella; Bacteria; Genetics","score_opus":0.004047816919003586,"score_gpt":0.230845774536634,"score_spread":0.2267979576176304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282546094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8339838,0.0029303015,0.16244453,0.00021698108,0.00022473573,0.0001241991,0.000055369645,0.000015708842,0.000004406131],"genre_scores_gemma":[0.97699046,0.00040012592,0.022464348,0.000027644557,0.000021048312,0.000025279418,0.000043809254,0.000018101739,0.000009178339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990463,0.00002161721,0.0002861068,0.00032155396,0.00009216676,0.00023221865],"domain_scores_gemma":[0.9996191,0.000007437173,0.000050792823,0.00027174296,0.000015037134,0.000035881865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015172976,0.00014501189,0.00025920485,0.00038306057,0.000019506282,0.000002489297,0.00022043507,0.00020696872,0.0000037306113],"category_scores_gemma":[0.000034848606,0.00017046156,0.000040898463,0.0003463651,0.000076169395,0.000001906046,0.00017012966,0.00018987486,1.8308604e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009801334,0.00005274186,0.027809676,0.000040020022,0.000014337599,0.000007730683,0.000037866743,0.074209705,0.89561856,0.000022172395,0.00008963885,0.001999535],"study_design_scores_gemma":[0.00056152407,0.00043333785,0.007914307,0.00003075182,0.000007979185,0.000007628531,0.000116516574,0.010221787,0.978058,0.00003491382,0.0024086318,0.00020461681],"about_ca_topic_score_codex":0.00009065883,"about_ca_topic_score_gemma":0.000019674324,"teacher_disagreement_score":0.1430067,"about_ca_system_score_codex":0.000026776845,"about_ca_system_score_gemma":0.000025909649,"threshold_uncertainty_score":0.695122},"labels":[],"label_agreement":null},{"id":"W4282925771","doi":"10.1101/2022.06.10.22276179","title":"Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council","keywords":"Nonsynonymous substitution; In silico; Germline; Biology; Genetics; Somatic cell; Germline mutation; Gene; Genome; Computational biology; Mutation","score_opus":0.008484671551115833,"score_gpt":0.27332967356697674,"score_spread":0.2648450020158609,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282925771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9757745,0.0016462272,0.021959277,0.000036633282,0.00025591083,0.0001687461,0.00007940794,0.0000066844063,0.00007260929],"genre_scores_gemma":[0.99664336,0.00031977007,0.0024182098,0.000010009619,0.00021357561,0.000019642854,0.00032571272,0.000015678452,0.000034009172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999146,0.00005384508,0.0003342136,0.0002442353,0.00012856428,0.00009318667],"domain_scores_gemma":[0.9993661,0.000014320417,0.00023851097,0.00028996557,0.00006596046,0.00002516087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031660518,0.00012514029,0.00020677851,0.000053922467,0.000029745688,0.0000071645336,0.000114352515,0.00016587535,0.000022508377],"category_scores_gemma":[0.00012646358,0.00013439247,0.00007393147,0.000042703006,0.00002850264,0.0000014292679,0.00034804046,0.00015937668,1.17100406e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010609906,0.000020411331,0.006902646,0.00044305492,0.000045773315,5.851039e-7,0.00027758421,0.006310453,0.9856374,0.000026889924,0.000005766898,0.00031879946],"study_design_scores_gemma":[0.0003870507,0.00018606138,0.49115756,0.00007187186,0.00014454656,0.0000093932695,0.00017674697,0.004263819,0.5020632,0.0004451736,0.00076142664,0.0003331418],"about_ca_topic_score_codex":0.000019915335,"about_ca_topic_score_gemma":0.000008765817,"teacher_disagreement_score":0.48425493,"about_ca_system_score_codex":0.000007767019,"about_ca_system_score_gemma":0.000039181465,"threshold_uncertainty_score":0.5480366},"labels":[],"label_agreement":null},{"id":"W4282940428","doi":"10.5281/zenodo.6646716","title":"Competition and coevolution drive the evolution and the diversification of CRISPR immunity","year":2022,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Coevolution; Diversification (marketing strategy); CRISPR; Competition (biology); Biology; Evolutionary biology; Immunity; Ecology; Genetics; Immune system; Business; Gene; Marketing","score_opus":0.010911360579708589,"score_gpt":0.23649478565163665,"score_spread":0.22558342507192805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282940428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89179224,0.0019513979,0.09705482,0.0016491705,0.00010669409,0.0007098724,0.00020829876,0.000072503644,0.006455],"genre_scores_gemma":[0.99921614,0.00018462956,0.000036760874,0.000026198928,0.000026887892,1.1452017e-7,0.00037886034,0.000067069646,0.00006336039],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99934983,0.00026178698,0.00008552778,0.000118572025,0.0001084473,0.000075820266],"domain_scores_gemma":[0.99962467,0.0000112984,0.000048324233,0.0001834111,0.000111681096,0.000020591819],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0005058024,0.000044440425,0.0000441596,0.00003165218,0.001520682,0.000045258235,0.00020299753,0.000016763624,0.00015338125],"category_scores_gemma":[0.0001150239,0.000035601082,0.000017445374,0.000106264786,0.0002124989,0.0000050660988,0.00068136916,0.00009428032,0.000007378703],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010224544,0.00021491197,0.0002391071,0.00013730921,0.00019252629,0.0000010860216,0.006686677,0.0045742835,0.8148336,0.0929624,0.031194942,0.047940727],"study_design_scores_gemma":[0.0038481043,0.0010182963,0.06363302,0.00002093302,0.000108764725,0.00028952892,0.015733872,0.009288774,0.01842253,0.0015718532,0.88570184,0.0003625083],"about_ca_topic_score_codex":0.00003919408,"about_ca_topic_score_gemma":5.2577417e-7,"teacher_disagreement_score":0.85450685,"about_ca_system_score_codex":0.000027168358,"about_ca_system_score_gemma":0.0000017756024,"threshold_uncertainty_score":0.9997792},"labels":[],"label_agreement":null},{"id":"W4282943453","doi":"10.1016/j.isci.2022.104614","title":"Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways","year":2022,"lang":"en","type":"article","venue":"iScience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Saskatchewan; McMaster University; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Harvard University; Canada Foundation for Innovation; National Science Foundation; Ministry of Agriculture of the People's Republic of China; National Sleep Foundation","keywords":"Immune system; Biology; Angiotensin-converting enzyme 2; Regulator; Oxidative stress; Signal transduction; Receptor; Cell biology; Regulation of gene expression; Gene; Immunology; Disease; Genetics; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty); Medicine; Biochemistry","score_opus":0.010171569325926165,"score_gpt":0.2670962812794355,"score_spread":0.25692471195350935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282943453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900692,0.0026220665,0.0070198495,0.000026551383,0.00007896662,0.00007995974,0.000057568755,0.000006411002,0.000039412545],"genre_scores_gemma":[0.9991788,0.000065162334,0.00058078486,0.000014738836,0.000017295646,0.000013119185,0.000091438036,0.0000061154287,0.000032515476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993771,0.000035562116,0.00012691796,0.000204745,0.00013726803,0.0001184548],"domain_scores_gemma":[0.9997409,0.000013447052,0.00006589482,0.00013433085,0.000025855155,0.000019546613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017577334,0.00006658255,0.00007231441,0.000026052592,0.00009488728,0.000007973205,0.00012972619,0.000028448201,0.000018482797],"category_scores_gemma":[0.000045902016,0.00006554301,0.000019000041,0.00010445338,0.00006558398,0.000004753276,0.00017871446,0.000054726355,4.2577838e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014494584,0.000017295903,0.0001426501,0.0000068408776,0.0000030177946,1.06949614e-7,0.00021907335,0.0011476921,0.99727947,0.000009234775,0.00024290141,0.0009172345],"study_design_scores_gemma":[0.00016338336,0.00013844359,0.00034282438,0.000010615412,0.0000023809912,0.0000013403245,0.00030418285,0.0009901327,0.9959399,0.000014498969,0.0020129797,0.00007933646],"about_ca_topic_score_codex":0.00001015425,"about_ca_topic_score_gemma":0.0000014857958,"teacher_disagreement_score":0.009109616,"about_ca_system_score_codex":0.000010879579,"about_ca_system_score_gemma":0.000024745235,"threshold_uncertainty_score":0.26727664},"labels":[],"label_agreement":null},{"id":"W4283021992","doi":"10.1093/g3journal/jkac154","title":"The MyLO CRISPR-Cas9 toolkit: a markerless yeast localization and overexpression CRISPR-Cas9 toolkit","year":2022,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Concordia University; University of Texas at Austin","keywords":"CRISPR; Cas9; Biology; Genome editing; Computational biology; Plasmid; Trans-activating crRNA; Guide RNA; Gene; Genetics; Green fluorescent protein; Selectable marker","score_opus":0.007227180478132296,"score_gpt":0.2660567411683282,"score_spread":0.2588295606901959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283021992","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30568546,0.6508432,0.039874233,0.00033797105,0.0011170764,0.0008776572,0.00023793832,0.00007093383,0.0009555552],"genre_scores_gemma":[0.9004485,0.09443628,0.001226471,0.00045446213,0.00066174683,0.00018715937,0.00026328486,0.00012213814,0.0021999597],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976339,0.00017201052,0.0004574086,0.0007009545,0.0004245948,0.00061114825],"domain_scores_gemma":[0.9986438,0.000036745063,0.00014651516,0.00086394715,0.00011779388,0.00019115853],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003810233,0.00038823928,0.0002481093,0.000082059465,0.0009362893,0.00015657194,0.00053907355,0.0001624804,0.00010957898],"category_scores_gemma":[0.000016856648,0.00035723703,0.00013723619,0.00024875515,0.0001364836,0.0000069383036,0.0010193582,0.00021008012,0.000009592036],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024980065,0.00010898104,0.008063342,0.0001110809,0.00017880427,0.000015412832,0.0006608667,0.03969868,0.34538046,0.00013234561,0.009088796,0.59631145],"study_design_scores_gemma":[0.0006982606,0.00027620577,0.0021407185,0.00001334582,0.00006618708,0.00010892987,0.001325955,0.00665939,0.06276183,0.00008505916,0.92527944,0.00058466673],"about_ca_topic_score_codex":0.000015734278,"about_ca_topic_score_gemma":0.000031217744,"teacher_disagreement_score":0.9161907,"about_ca_system_score_codex":0.00005360804,"about_ca_system_score_gemma":0.000114268965,"threshold_uncertainty_score":0.99988794},"labels":[],"label_agreement":null},{"id":"W4283070781","doi":"10.1038/s41467-022-31270-y","title":"Peptide fusion improves prime editing efficiency","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Qatar Biomedical Research Institute, Hamad Bin Khalifa University; National Human Genome Research Institute; Fundação de Amparo à Pesquisa do Estado de São Paulo; American Heart Association; U.S. Department of Health and Human Services","keywords":"Prime (order theory); Computer science; Genome editing; Translation (biology); Computational biology; Peptide; Function (biology); Biology; Genome; Biochemistry; Cell biology; Gene; Mathematics","score_opus":0.0066143440469700636,"score_gpt":0.3022269127878583,"score_spread":0.2956125687408882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283070781","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8917235,0.05915281,0.010339911,0.005568732,0.0015778103,0.00077780127,0.00011937313,0.00017529358,0.030564753],"genre_scores_gemma":[0.9944765,0.00018756285,0.004109379,0.00023689689,0.0001294257,0.000052834264,0.00025900643,0.000013796062,0.0005346124],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99946845,0.000049138824,0.00010770839,0.00014631714,0.00010256656,0.00012584656],"domain_scores_gemma":[0.9989006,0.000018959554,0.00003960123,0.0009673611,0.000041276748,0.00003219101],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016102366,0.000071580325,0.00005326905,0.000034672426,0.00043180105,0.000011645849,0.0006608417,0.00007641326,0.000018475333],"category_scores_gemma":[0.00009040301,0.00007830764,0.00005091799,0.0001253301,0.000033328197,0.0000014580555,0.0009523732,0.00044225104,0.000002667745],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004472067,0.000068466805,0.0004502163,0.0000031962768,0.000011456443,2.6955792e-7,0.00009402761,0.00033122997,0.99115556,0.0004463886,0.0046763355,0.0027583994],"study_design_scores_gemma":[0.00026108892,0.00013623384,0.004697694,0.000004756614,0.000016581182,0.000023744054,0.0004783658,0.0030392082,0.07213908,0.000035206285,0.91895765,0.00021037742],"about_ca_topic_score_codex":0.0000059681247,"about_ca_topic_score_gemma":0.000028783486,"teacher_disagreement_score":0.9190165,"about_ca_system_score_codex":0.000016270522,"about_ca_system_score_gemma":0.000033280317,"threshold_uncertainty_score":0.33211082},"labels":[],"label_agreement":null},{"id":"W4283074872","doi":"10.1101/2022.06.17.496490","title":"Rapid, scalable, combinatorial genome engineering by Marker-less Enrichment and Recombination of Genetically Engineered loci (MERGE)","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Faculty of Arts and Sciences; National Institutes of Health; Army Research Office; University of Toronto; York University; Fonds de recherche du Québec – Nature et technologies; Welch Foundation; University of Washington; Concordia University; Harvard University","keywords":"CRISPR; Biology; Genome editing; Genetics; Computational biology; Genome engineering; Genome; Cas9; Merge (version control); Gene; Homologous recombination; Locus (genetics); Computer science","score_opus":0.005339206555632564,"score_gpt":0.2121005421229024,"score_spread":0.20676133556726986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283074872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9714724,0.013389133,0.012301586,0.000051934785,0.0016262681,0.00068884424,0.0003675527,0.00008970854,0.000012617961],"genre_scores_gemma":[0.9922583,0.0029954233,0.0040311534,0.000028047842,0.00029366268,0.0002106265,0.000019153636,0.00015216398,0.000011442818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973695,0.000085147585,0.00063779287,0.00096254516,0.0003867409,0.00055826164],"domain_scores_gemma":[0.9983179,0.000027939575,0.0002405089,0.0009204528,0.00023624797,0.00025697114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062202825,0.0005691228,0.00055140816,0.0001975619,0.00009679193,0.000068399786,0.0004788879,0.00050923385,0.000057142846],"category_scores_gemma":[0.00014099405,0.0007208963,0.00015562393,0.00026629787,0.000066706714,0.000007517299,0.0009461893,0.00049360626,0.000001616774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046068977,0.00014481856,0.00083996984,0.00048051713,0.00025661907,0.0000052930172,0.0000062412405,0.0031392549,0.9945531,0.00016598275,0.0003462309,0.000015943957],"study_design_scores_gemma":[0.0019326212,0.00043023404,0.032598328,0.000107558706,0.0002135967,1.2007465e-7,0.000011428101,0.0034298839,0.91826916,0.0000030174797,0.041481018,0.0015230591],"about_ca_topic_score_codex":0.000018817167,"about_ca_topic_score_gemma":2.8851824e-7,"teacher_disagreement_score":0.076283924,"about_ca_system_score_codex":0.00011880838,"about_ca_system_score_gemma":0.00017920186,"threshold_uncertainty_score":0.99952424},"labels":[],"label_agreement":null},{"id":"W4283585999","doi":"10.1038/s41467-022-31365-6","title":"The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Université Laval; U.S. Department of Health and Human Services","keywords":"Blunt; DNA; Computer science; Computational biology; Genetics; Medicine; Biology; Surgery","score_opus":0.014280397036156706,"score_gpt":0.32174745589386144,"score_spread":0.30746705885770476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283585999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6461233,0.2477899,0.010932493,0.07251081,0.0014751318,0.0027961012,0.0022087144,0.00011189737,0.016051639],"genre_scores_gemma":[0.9908967,0.0008691492,0.0057935514,0.0011644062,0.00004543238,0.0001647006,0.00021511698,0.00001823098,0.00083272345],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993758,0.000037885195,0.00019417243,0.00014859124,0.00010520873,0.00013833679],"domain_scores_gemma":[0.99830574,0.0000839664,0.000093013776,0.001399771,0.000089834364,0.000027676002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024249518,0.00008529419,0.000087205604,0.000021625396,0.00043251837,0.000012899126,0.0008344121,0.00009618525,0.000032481177],"category_scores_gemma":[0.00008836667,0.00007736014,0.00009673653,0.00008266137,0.00005826865,0.000001670613,0.00047685095,0.00027985434,4.986935e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001312682,0.00019120482,0.006254435,0.000052983218,0.00034844992,4.0367874e-7,0.0022268933,0.0003599777,0.757822,0.009952247,0.21414886,0.008511277],"study_design_scores_gemma":[0.00029617798,0.00008851908,0.0015786135,0.000004061293,0.000029274986,0.0000044495982,0.00044237013,0.0006796993,0.11921302,0.00043036175,0.8771108,0.00012266487],"about_ca_topic_score_codex":0.0000049208993,"about_ca_topic_score_gemma":0.00014681676,"teacher_disagreement_score":0.6629619,"about_ca_system_score_codex":0.000013272718,"about_ca_system_score_gemma":0.000054048727,"threshold_uncertainty_score":0.33266252},"labels":[],"label_agreement":null},{"id":"W4283656416","doi":"10.31235/osf.io/wqjsd","title":"Guerrilla eugenics: Gene drives in heritable human genome editing","year":2022,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Genome editing; Eugenics; CRISPR; Genome; Biology; Genetics; Bioethics; Human genome; Cas9; Human genetics; Gene","score_opus":0.00999426592768395,"score_gpt":0.3021457444646567,"score_spread":0.29215147853697276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283656416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97235954,0.006374243,0.0057643894,0.00007108166,0.00082927675,0.0003891735,0.00008016626,0.00005272612,0.01407938],"genre_scores_gemma":[0.9887257,0.00052427384,0.004514164,0.000104559585,0.0011249115,0.00012818586,0.0012339016,0.000076244396,0.0035680197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834543,0.000045827608,0.00036300535,0.0006862032,0.00016279942,0.00039670622],"domain_scores_gemma":[0.99915063,0.0000052406426,0.00008259411,0.00064678787,0.00003396034,0.000080766134],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024408841,0.00029810105,0.00028324814,0.00010504242,0.000095716736,0.00004362088,0.00042665642,0.00027662836,0.00046223268],"category_scores_gemma":[0.00002597051,0.00034784988,0.00016078482,0.00007497938,0.000030285115,0.0000012837744,0.0017939591,0.00041273938,0.0000050246995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000068412537,0.00004540884,0.002078467,0.00010361107,0.00008039224,0.000017495442,0.00014353113,0.07118093,0.9255231,0.0000695168,0.00048330476,0.00026739898],"study_design_scores_gemma":[0.001982098,0.00056142214,0.03512751,0.0001099511,0.000116880095,0.00006935159,0.002070108,0.0022382701,0.5559247,0.0012476064,0.39718807,0.0033640247],"about_ca_topic_score_codex":0.00015856505,"about_ca_topic_score_gemma":0.00022227969,"teacher_disagreement_score":0.39670476,"about_ca_system_score_codex":0.000051678806,"about_ca_system_score_gemma":0.00007060172,"threshold_uncertainty_score":0.99989736},"labels":[],"label_agreement":null},{"id":"W4283730852","doi":"10.1101/2022.06.29.498089","title":"Genetic transformation and cell division delay in competent <i>Staphylococcus aureus</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Agence Nationale de la Recherche; York University","keywords":"Staphylococcus aureus; Transformation (genetics); Biology; Cell division; Genetic recombination; Virulence; Genetics; Gene; DNA; Horizontal gene transfer; Cell biology; Microbiology; Cell; Bacteria; Genome; Recombination","score_opus":0.005436415270981572,"score_gpt":0.22106778782673395,"score_spread":0.21563137255575238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283730852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9814095,0.006237013,0.011060423,0.000051452713,0.00043799318,0.0005957714,0.00013925848,0.00004932872,0.000019252662],"genre_scores_gemma":[0.9956429,0.0014704334,0.002374881,0.0001086978,0.00014073667,0.00017591633,0.000003298365,0.00008016413,0.000002947707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811935,0.00008665748,0.00043867156,0.000723976,0.00023819214,0.0003931745],"domain_scores_gemma":[0.99894094,0.000011830236,0.00013111731,0.0006831785,0.000077248245,0.0001557036],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000287845,0.0004013045,0.00030961013,0.00017781563,0.00009880153,0.00007265981,0.00031824218,0.00033378298,0.000021824431],"category_scores_gemma":[0.000020034133,0.00047012005,0.000105753956,0.00017402245,0.0000463304,0.0000058645483,0.00047702552,0.00046620425,0.0000034912052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019880199,0.000078120844,0.007903578,0.0002963351,0.000028621069,0.000017230903,0.000022149135,0.009353511,0.9821634,0.000013630581,0.00009632579,0.0000071633126],"study_design_scores_gemma":[0.0011039431,0.00019189627,0.20202057,0.00010746806,0.00006082449,3.764676e-8,0.000014935842,0.0022691474,0.77267814,0.0000014054879,0.020580208,0.0009714401],"about_ca_topic_score_codex":0.000037705606,"about_ca_topic_score_gemma":0.0000106994,"teacher_disagreement_score":0.20948532,"about_ca_system_score_codex":0.00006983321,"about_ca_system_score_gemma":0.00014476312,"threshold_uncertainty_score":0.99977505},"labels":[],"label_agreement":null},{"id":"W4283816811","doi":"10.1038/s41467-022-31631-7","title":"Author Correction: A truncated anti-CRISPR protein prevents spacer acquisition but not interference","year":2022,"lang":"en","type":"erratum","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Interference (communication); Computational biology; RNA interference; Computer science; Biology; Genetics; Telecommunications; Gene; RNA","score_opus":0.014520866461370248,"score_gpt":0.3299147666604384,"score_spread":0.31539390019906816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283816811","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06745714,0.33933735,0.051246412,0.0431456,0.31740838,0.017537968,0.0070629045,0.0020085196,0.15479569],"genre_scores_gemma":[0.7254518,0.0016918652,0.0013705267,0.00031803362,0.0007683463,0.00053366146,0.0112194065,0.00009437111,0.25855196],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983922,0.0002258514,0.00033825563,0.00051156717,0.00025504504,0.00027703703],"domain_scores_gemma":[0.9969061,0.000023706969,0.00021326126,0.0025685143,0.00019741118,0.00009103397],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00022509178,0.00034651472,0.000286434,0.00014458207,0.00037707415,0.00006170154,0.0013108404,0.001129495,0.00020664974],"category_scores_gemma":[0.00020097852,0.00038604706,0.00019258169,0.00028325347,0.000089583715,0.000005787139,0.0011670375,0.0027135657,0.000015802985],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034564488,0.00013936634,0.000030367986,0.000050467548,0.00013386477,0.0000015997509,0.00007366573,0.000061557934,0.086793326,0.000054496795,0.91171974,0.00090700877],"study_design_scores_gemma":[0.00021974738,0.00015338766,0.0011581802,0.00013723643,0.00008289342,0.00003040802,0.00009856283,0.0006985412,0.030920213,0.000012358714,0.96604943,0.0004390624],"about_ca_topic_score_codex":0.000041197018,"about_ca_topic_score_gemma":0.00019873338,"teacher_disagreement_score":0.6579947,"about_ca_system_score_codex":0.00009303704,"about_ca_system_score_gemma":0.00024979853,"threshold_uncertainty_score":0.99985915},"labels":[],"label_agreement":null},{"id":"W4283835454","doi":"10.1182/bloodadvances.2022007250","title":"In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"CRISPR; In vivo; Biology; Myeloid leukemia; Leukemia; Genome editing; Genome; Myeloid; Computational biology; Gene; Cancer research; Genetics","score_opus":0.003674562314736957,"score_gpt":0.23993785539738527,"score_spread":0.23626329308264832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283835454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914736,0.0067970688,0.0010879008,0.000051514533,0.000117740616,0.00014317934,0.000050244304,0.0000084542025,0.00027028754],"genre_scores_gemma":[0.99572915,0.0014096798,0.0018921162,0.00024782104,0.000068530906,0.000059369875,0.000046747722,0.000022614006,0.00052395614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898446,0.000029558565,0.00019985286,0.00034264778,0.0001457158,0.00029777733],"domain_scores_gemma":[0.9997126,0.000011987694,0.000042817108,0.00018387202,0.0000042328347,0.000044507728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010656278,0.0001549908,0.00014195307,0.00008240376,0.00007180316,0.000010175735,0.00020604314,0.00003814061,0.00010506765],"category_scores_gemma":[0.000013385315,0.00018012882,0.000054429176,0.00011975568,0.000033841632,0.000011186637,0.00028051602,0.00014977914,0.0000016676779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067021516,0.00006192544,0.08527095,0.0000147012315,0.00003920701,0.000096556585,0.0001232525,0.07095738,0.8428845,0.000003480006,0.00010216144,0.0003788981],"study_design_scores_gemma":[0.001520799,0.00022970341,0.023976415,0.000008534782,0.000024380293,0.00007565049,0.0011395718,0.00008316922,0.87588125,0.000024500936,0.09669898,0.00033705484],"about_ca_topic_score_codex":0.00006176769,"about_ca_topic_score_gemma":0.00027593022,"teacher_disagreement_score":0.096596815,"about_ca_system_score_codex":0.000048589896,"about_ca_system_score_gemma":0.000030735133,"threshold_uncertainty_score":0.734544},"labels":[],"label_agreement":null},{"id":"W4284668557","doi":"10.4324/9781003271918-11","title":"Regulation of Gene-Edited Products","year":2022,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Gene technology; Scope (computer science); Business; Emerging technologies; Biotechnology; Agriculture; Genome editing; CRISPR; Gene; Biology; Computer science; Genetics","score_opus":0.008766461974532942,"score_gpt":0.24740084907107565,"score_spread":0.23863438709654272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284668557","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022462015,0.0036905261,0.004191314,0.00014155929,0.0007693585,0.00045175763,0.000095241885,0.000034488374,0.98837954],"genre_scores_gemma":[0.060931206,0.00043023351,0.0024130736,0.00004569117,0.00070311845,0.000010623269,0.0014533435,0.00007148738,0.93394125],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99934566,0.000003992752,0.00017726525,0.00026061496,0.000128722,0.00008376331],"domain_scores_gemma":[0.9994635,0.0000025114975,0.000074476215,0.00036336854,0.00007185974,0.000024313971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005919376,0.00013843422,0.00013127975,0.00005088494,0.00001997593,0.0000027907588,0.00009914556,0.00014360689,0.00075230683],"category_scores_gemma":[0.000014321321,0.00014594653,0.00007012866,0.000015634838,0.000022783752,5.570693e-7,0.000074652045,0.000072190654,0.000004311945],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021901848,0.000009151766,0.0000063423363,0.00006989951,0.00008673204,0.0000010726245,0.000012415195,0.0008873825,0.9780191,0.007135392,0.011914357,0.0018362425],"study_design_scores_gemma":[0.00009130957,0.000090948095,0.00008858409,0.000006160189,0.000022474915,0.0000073333904,0.0000019482004,0.000018884792,0.37329245,0.00013046815,0.62610185,0.00014758238],"about_ca_topic_score_codex":0.0000033115152,"about_ca_topic_score_gemma":0.0000030956828,"teacher_disagreement_score":0.6141875,"about_ca_system_score_codex":0.00000835916,"about_ca_system_score_gemma":0.000041282976,"threshold_uncertainty_score":0.82372326},"labels":[],"label_agreement":null},{"id":"W4284898993","doi":"10.1016/j.endeavour.2022.100821","title":"Neck of the woods: Microbes, memory, and resistance","year":2022,"lang":"en","type":"article","venue":"Endeavour","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Social Sciences and Humanities Research Council of Canada","keywords":"Horizontal gene transfer; Glossary; Resistance (ecology); Genome; History; Biology; Genetics; Gene; Literature; Genealogy; Philosophy; Linguistics; Ecology; Art","score_opus":0.003762786922808364,"score_gpt":0.2350827163760704,"score_spread":0.23131992945326202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284898993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99185187,0.0044149505,0.0002670771,0.00024221011,0.00016358001,0.00007447163,0.000022380964,0.0000042740603,0.00295918],"genre_scores_gemma":[0.9957387,0.00004586826,0.0005391258,0.00009573483,0.000046470566,0.00000817931,0.000004880253,0.0000080687005,0.0035129923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996455,0.000021930904,0.00007166839,0.00011433188,0.00006409017,0.00008252872],"domain_scores_gemma":[0.99974144,0.0000034635943,0.000025257363,0.00020335919,0.000009170514,0.000017293594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071198185,0.00005006167,0.00004997489,0.000009358067,0.00007043292,0.0000032125376,0.0001222824,0.000018634266,0.000023466588],"category_scores_gemma":[0.00001561825,0.000042757503,0.000033056596,0.000044138284,0.000023286482,4.334186e-7,0.00018766674,0.000057757487,2.883044e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021816815,0.00001931953,0.0015074332,0.000024362707,0.000021070533,0.0000010170097,0.00013348332,0.00040021387,0.9854368,0.00019207173,0.011624194,0.000618198],"study_design_scores_gemma":[0.00038326392,0.00006341121,0.012259246,0.0000073639703,0.00001201517,0.000020894975,0.00031917216,0.000017371676,0.66570127,0.00014507984,0.32094488,0.00012607242],"about_ca_topic_score_codex":0.0000065829486,"about_ca_topic_score_gemma":0.000020778287,"teacher_disagreement_score":0.3197356,"about_ca_system_score_codex":0.0000043820373,"about_ca_system_score_gemma":0.000018470122,"threshold_uncertainty_score":0.17436004},"labels":[],"label_agreement":null},{"id":"W4284988218","doi":"10.1002/adbi.202101326","title":"Genome‐Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson's Disease Patients from India","year":2022,"lang":"en","type":"article","venue":"Advanced Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Parkinson's Clinic of Eastern Toronto & Movement Disorders Centre","funders":"","keywords":"Disease; Genetics; LRRK2; Biology; Polygenic risk score; Parkinson's disease; Genome-wide association study; Gene; Bioinformatics; Medicine; Genotype; Single-nucleotide polymorphism; Internal medicine; Mutation","score_opus":0.0037029708352591586,"score_gpt":0.26148226483343073,"score_spread":0.25777929399817157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284988218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921928,0.0018785719,0.0005015538,0.000012882731,0.00034240144,0.000365114,0.0046655666,0.000015804353,0.000025320118],"genre_scores_gemma":[0.9932321,0.0007292388,0.00050710555,0.00012143504,0.000059878188,0.00017411221,0.005115208,0.000034437686,0.000026489972],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983568,0.00018130975,0.00036400146,0.00053820555,0.00012482761,0.0004348373],"domain_scores_gemma":[0.9991529,0.00005398375,0.00018980683,0.00044253463,0.000033855296,0.000126938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014617582,0.00022069864,0.00027567428,0.00008931288,0.00009098907,0.000004535145,0.0003215652,0.00012187627,0.0001452386],"category_scores_gemma":[0.00018831599,0.00023945498,0.0001062696,0.00018835953,0.000058718702,0.0000050679055,0.00040507413,0.00020682639,0.000006094367],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001903831,0.00021238015,0.98820007,0.000008022808,0.000071790055,0.0000059467307,0.00007274192,0.0017625773,0.0087194815,0.000012943393,0.00003679751,0.00070685457],"study_design_scores_gemma":[0.0023075016,0.00025204796,0.9818314,0.0000064792316,0.00003969396,0.0000016008983,0.000057944962,0.000019247425,0.0051880837,0.0005582721,0.009482837,0.00025494662],"about_ca_topic_score_codex":0.00014784101,"about_ca_topic_score_gemma":0.00014366831,"teacher_disagreement_score":0.00944604,"about_ca_system_score_codex":0.00004259783,"about_ca_system_score_gemma":0.00007574486,"threshold_uncertainty_score":0.97646904},"labels":[],"label_agreement":null},{"id":"W4285045763","doi":"10.1016/j.ymthe.2022.07.010","title":"A precise and efficient adenine base editor","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Institutes of Health","keywords":"Bystander effect; Genome editing; Computational biology; Mutation; Gene; Biology; Genetics; Genome","score_opus":0.004072216163870348,"score_gpt":0.25460940677750293,"score_spread":0.2505371906136326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285045763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9776759,0.00808628,0.013146806,0.00017639369,0.0005549165,0.00018204004,0.000019105046,0.000016456108,0.0001420761],"genre_scores_gemma":[0.99818295,0.00014992587,0.00057589624,0.00028527295,0.00041330344,0.00008159935,0.00004939717,0.00002709745,0.00023457516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993174,0.000041640495,0.00008900675,0.00025282797,0.000140634,0.0001584781],"domain_scores_gemma":[0.9996505,0.0000039402357,0.000019891517,0.00024544203,0.000017284683,0.00006295243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010872157,0.00010781293,0.000076853175,0.00003316457,0.00009018131,0.000013280504,0.000111593225,0.000033010045,0.00007801171],"category_scores_gemma":[0.00001030652,0.00011132019,0.000052663236,0.0000670773,0.000021949347,4.854399e-7,0.00012311153,0.000076256154,0.0000026399023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071075745,0.000053196294,0.00006354066,0.0000032542114,0.00002699221,0.000011750236,0.000058813617,0.008715105,0.98453623,0.000013688777,0.0021779384,0.004268404],"study_design_scores_gemma":[0.0010140466,0.00044697017,0.0003297747,0.0000020913476,0.000006842951,0.000038959108,0.00005861924,0.0013235019,0.7142528,0.00001408616,0.28230077,0.00021152367],"about_ca_topic_score_codex":0.0000039123834,"about_ca_topic_score_gemma":4.1748027e-7,"teacher_disagreement_score":0.28012282,"about_ca_system_score_codex":0.000007698044,"about_ca_system_score_gemma":0.000018750696,"threshold_uncertainty_score":0.45395055},"labels":[],"label_agreement":null},{"id":"W4285140022","doi":"10.1007/978-3-031-06220-9_8","title":"Reconciliation with Segmental Duplication, Transfer, Loss and Gain","year":2022,"lang":"en","type":"book-chapter","venue":"Lecture notes in computer science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"","keywords":"Gene duplication; Tree (set theory); CRISPR; Genome; Set (abstract data type); Gene; Computer science; Dynamic programming; Diversification (marketing strategy); Segmental duplication; Theoretical computer science; Gene family; Biology; Computational biology; Algorithm; Combinatorics; Genetics; Mathematics; Programming language","score_opus":0.006469011369344214,"score_gpt":0.240688279890445,"score_spread":0.23421926852110078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285140022","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012214337,0.00084633206,0.986018,0.00014919625,0.00013850603,0.00017551478,0.000010612641,0.0000096790245,0.0004378086],"genre_scores_gemma":[0.9810017,0.00037194035,0.017622048,0.0003995958,0.00022195072,0.000015675858,0.00008057841,0.00002714664,0.0002594046],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907774,0.0000057982425,0.00011757218,0.00048580818,0.0001691704,0.00014391217],"domain_scores_gemma":[0.9996344,0.000014516148,0.000023787543,0.00024811729,0.000035347257,0.000043842036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014700547,0.00015345884,0.00010715168,0.00007726339,0.00007957398,0.000031163454,0.00019083213,0.00008664114,0.000022855338],"category_scores_gemma":[0.000006658305,0.00014429104,0.000022295746,0.0000615761,0.0001557026,0.0000042826578,0.00009918229,0.00014484575,6.7130503e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000091927875,0.00003971349,0.0012675545,0.000121234334,0.00005319676,0.000028445418,0.0008038362,0.19286305,0.10968817,0.001223318,0.00003891713,0.69378066],"study_design_scores_gemma":[0.004120721,0.0044474844,0.0043578986,0.0004941697,0.0001224582,0.001181466,0.000006541534,0.1165789,0.7578775,0.009676921,0.09682388,0.004312023],"about_ca_topic_score_codex":0.000006087225,"about_ca_topic_score_gemma":0.00006227946,"teacher_disagreement_score":0.9687873,"about_ca_system_score_codex":0.000038319562,"about_ca_system_score_gemma":0.00008607073,"threshold_uncertainty_score":0.5884018},"labels":[],"label_agreement":null},{"id":"W4285149996","doi":"10.1007/978-1-0716-1979-7_36","title":"Designing Genetically Engineered Mouse Models (GEMMs) Using CRISPR Mediated Genome Editing","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"CRISPR; Genome editing; Cas9; Biology; Computational biology; Genome; Embryonic stem cell; Genetics; Gene","score_opus":0.026190015472952927,"score_gpt":0.388640501076041,"score_spread":0.36245048560308807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285149996","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13120127,0.002310014,0.8656462,0.000040278257,0.0002854852,0.0002677166,0.000032411346,0.000037066624,0.00017956023],"genre_scores_gemma":[0.2392841,0.00006112706,0.7597928,0.00031546515,0.00014412035,0.00010290455,0.0001812512,0.00007889591,0.00003934767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996993,0.00097178284,0.0005031599,0.0007081352,0.00015268274,0.0006712225],"domain_scores_gemma":[0.999127,0.000075436765,0.00009774184,0.00051058026,0.000062295076,0.00012696873],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014722777,0.00031669863,0.00036244345,0.0002541011,0.00013915494,0.000018353769,0.00046831102,0.00023465576,0.000056369696],"category_scores_gemma":[0.0003700449,0.00037232594,0.00014742538,0.00034391644,0.00007990692,0.0000035947155,0.00061690086,0.00039797515,0.0000013087655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020032205,0.000028530978,0.000110803034,0.000009783855,0.00004266121,0.000018410366,0.000057914487,0.29877773,0.70000803,0.0001437851,0.0000069515813,0.0007753601],"study_design_scores_gemma":[0.0006835222,0.0002628502,0.000028974862,0.000004604115,0.000030794887,0.00006975883,0.00018739325,0.113045916,0.8812437,0.00074149703,0.0032094968,0.0004914558],"about_ca_topic_score_codex":0.0000275923,"about_ca_topic_score_gemma":0.000003925071,"teacher_disagreement_score":0.18573181,"about_ca_system_score_codex":0.00007265455,"about_ca_system_score_gemma":0.000087056826,"threshold_uncertainty_score":0.99987286},"labels":[],"label_agreement":null},{"id":"W4285150486","doi":"10.1007/978-1-0716-2257-5_14","title":"Deep Mutational Scanning of Protein–Protein Interactions Between Partners Expressed from Their Endogenous Loci In Vivo","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec; PROTEO; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; Protein-fragment complementation assay; Complementation; Genome editing; Computational biology; Biology; Gene; Mutant; Genome; Protein–protein interaction; Genetics","score_opus":0.030589259048526732,"score_gpt":0.40357880878622127,"score_spread":0.37298954973769455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285150486","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4851316,0.0007445458,0.5135887,0.000034164987,0.000049043058,0.0002308404,0.000053419357,0.0000056663584,0.00016200091],"genre_scores_gemma":[0.7915359,0.0000048720135,0.20782562,0.000036041994,0.000044091707,0.0003085818,0.00020003713,0.000022650234,0.000022191442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99799955,0.00083724887,0.00039447128,0.00041367442,0.00007860332,0.0002764488],"domain_scores_gemma":[0.9994342,0.00007630459,0.0001109024,0.00030308857,0.000032039068,0.00004346642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005672695,0.00017208687,0.00027566322,0.000172669,0.00005045311,0.000005326096,0.00027017275,0.000110688234,0.000091838985],"category_scores_gemma":[0.00019164031,0.00018907558,0.00010062489,0.00021822157,0.00007549093,0.0000023604412,0.0002640312,0.00025356875,3.7415933e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044267985,0.00004804198,0.0018488299,0.0000092965365,0.000053940326,0.000011705548,0.00026247202,0.017072132,0.9755151,0.00009979681,0.0000024755143,0.0050319335],"study_design_scores_gemma":[0.0005211213,0.00013804065,0.00040081434,0.000011088172,0.000008564762,0.000006918861,0.00033434125,0.000726736,0.992547,0.0023182696,0.0027991424,0.00018800679],"about_ca_topic_score_codex":0.00021082834,"about_ca_topic_score_gemma":0.00003915708,"teacher_disagreement_score":0.30640432,"about_ca_system_score_codex":0.00004132168,"about_ca_system_score_gemma":0.000062618936,"threshold_uncertainty_score":0.77102786},"labels":[],"label_agreement":null},{"id":"W4285228088","doi":"10.1007/978-1-0716-2257-5_19","title":"High-Throughput Gene Mutagenesis Screening Using Base Editing","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; PROTEO; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Mutagenesis; Cas9; Computational biology; Base (topology); Biology; Genetics; Gene; Mutation; Computer science","score_opus":0.024386591641005748,"score_gpt":0.41566940563666793,"score_spread":0.39128281399566217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285228088","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26713926,0.0016413062,0.73043877,0.00005445433,0.0004985432,0.00013882777,0.000023877523,0.00001822257,0.000046751244],"genre_scores_gemma":[0.19063795,0.000025537318,0.8084207,0.00038767976,0.00024189228,0.000064315434,0.00013160484,0.000051380004,0.00003892163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974122,0.0009590702,0.00037075678,0.00065017183,0.000110225796,0.0004975471],"domain_scores_gemma":[0.9992607,0.00004375433,0.00009915422,0.0004863897,0.00003518675,0.00007479045],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013676538,0.00024151626,0.0002907721,0.00017406019,0.00017240497,0.000012617897,0.00033256956,0.00015606738,0.000086361324],"category_scores_gemma":[0.00024631256,0.00028467766,0.00013885899,0.00031520234,0.00007037486,0.0000022228674,0.0006860094,0.0002573028,6.790289e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022124294,0.00002712778,0.0012187965,0.000008006914,0.00004177004,0.000039995793,0.000028208848,0.1095962,0.8790201,0.00012749755,0.000019537692,0.009850654],"study_design_scores_gemma":[0.0005738815,0.00018902421,0.00012965185,0.000004782077,0.00002684892,0.000108477565,0.00015312522,0.009329591,0.9827099,0.00034078714,0.0060965866,0.00033733732],"about_ca_topic_score_codex":0.00012283136,"about_ca_topic_score_gemma":0.000006654099,"teacher_disagreement_score":0.10368983,"about_ca_system_score_codex":0.000043609103,"about_ca_system_score_gemma":0.00004806645,"threshold_uncertainty_score":0.99996054},"labels":[],"label_agreement":null},{"id":"W4285240041","doi":"10.1016/j.csbj.2022.06.015","title":"Development and clinical translation of <i>ex vivo</i> gene therapy","year":2022,"lang":"en","type":"review","venue":"Computational and Structural Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Science Foundation of Fuzhou; Natural Science Foundation of Fujian Province","keywords":"Genetic enhancement; Genome editing; Ex vivo; Medicine; Viral vector; Computational biology; Vector (molecular biology); Translational medicine; Bioinformatics; Biology; Gene; Biotechnology; Genome; In vivo; Pathology; Genetics","score_opus":0.03992504770784148,"score_gpt":0.36633512050429645,"score_spread":0.32641007279645495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285240041","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022047158,0.9740086,0.0035582471,0.000043032815,0.00018433393,0.0001232813,0.000020766518,0.0000067657984,0.000007813056],"genre_scores_gemma":[0.0013828985,0.9804109,0.017944194,0.000021042533,0.00010319054,0.000002981273,0.00011219627,0.000013699761,0.000008913379],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989509,0.000053320728,0.0005437116,0.00023307002,0.00010217184,0.00011681808],"domain_scores_gemma":[0.9995837,0.000038882947,0.00022414971,0.00007681545,0.000025212383,0.000051220362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018110857,0.00018407134,0.00044509888,0.000105973726,0.00012566143,0.000013491001,0.00012782613,0.000328011,0.000020570755],"category_scores_gemma":[0.000014933809,0.00014677225,0.00012783773,0.00007007848,0.00012950247,0.0000022392694,0.00008203674,0.00035436935,1.8444405e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010872594,0.0000055772457,0.000014265379,0.00014093611,0.00018070929,0.000002929489,0.000015062605,0.00006221904,0.00024198048,0.000035801626,0.00002363983,0.999266],"study_design_scores_gemma":[0.0003867061,0.000183277,0.0001338349,0.00008795452,0.000061466446,0.0014105362,0.000013594552,0.00012547238,0.00068238156,0.00020233175,0.99651814,0.00019430442],"about_ca_topic_score_codex":3.439287e-7,"about_ca_topic_score_gemma":6.1023525e-7,"teacher_disagreement_score":0.9990717,"about_ca_system_score_codex":0.000009136594,"about_ca_system_score_gemma":0.00013386137,"threshold_uncertainty_score":0.59851986},"labels":[],"label_agreement":null},{"id":"W4285240815","doi":"10.1007/978-1-0716-1979-7_24","title":"Reprogramming Mouse Oviduct Epithelial Cells Using In Vivo Electroporation and CRISPR/Cas9-Mediated Genetic Manipulation","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"CRISPR; Electroporation; Reprogramming; Biology; Genome editing; Somatic cell; Cell biology; Cas9; In vivo; Stem cell; Oviduct; Gene; Genetics","score_opus":0.01710548588564788,"score_gpt":0.39052290320667404,"score_spread":0.3734174173210262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285240815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5160754,0.00087933766,0.4827226,0.000018686454,0.000087075496,0.00018944225,0.0000074871637,0.000008461031,0.000011543718],"genre_scores_gemma":[0.59235543,0.00010287435,0.40717927,0.000106235835,0.00005198948,0.00006157276,0.00008407749,0.000034575663,0.00002398847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978563,0.00079834374,0.00035888405,0.00055571506,0.00007890368,0.00035183952],"domain_scores_gemma":[0.9995141,0.000029768747,0.00008877727,0.00029442384,0.000025146597,0.00004775352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008535321,0.00018493728,0.00021523862,0.00022132286,0.0000716409,0.000014664139,0.00013654956,0.00015846893,0.000020322133],"category_scores_gemma":[0.00014238617,0.00021852477,0.000052489537,0.00028297314,0.00005343125,0.0000028834156,0.00020668587,0.00021612109,3.1371044e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004651726,0.000035718844,0.003274365,0.000011647619,0.000013845646,0.000018494584,0.00006623106,0.020669539,0.971798,0.00005114145,0.000005006991,0.0040094913],"study_design_scores_gemma":[0.00054771965,0.00027673892,0.0005715379,0.0000021635885,0.0000126693085,0.00004468068,0.00009221565,0.014822516,0.98037946,0.00035057316,0.0026508677,0.0002488811],"about_ca_topic_score_codex":0.00015263038,"about_ca_topic_score_gemma":0.00004851156,"teacher_disagreement_score":0.07628006,"about_ca_system_score_codex":0.000060141643,"about_ca_system_score_gemma":0.00004350398,"threshold_uncertainty_score":0.8911181},"labels":[],"label_agreement":null},{"id":"W4285257629","doi":"10.1007/978-1-0716-2301-5_13","title":"Targeted Gene Editing in Porcine Germ Cells","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institutes of Health","keywords":"CRISPR; Germline; Genome editing; Human disease; Cas9; Biology; Gene; Computational biology; Disease; Genotype; Genetic enhancement; Genetics; Bioinformatics; Medicine; Pathology","score_opus":0.009756448916183559,"score_gpt":0.38869942157065507,"score_spread":0.3789429726544715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285257629","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.27999893,0.002976027,0.71565837,0.0001112436,0.00062826695,0.00020809803,0.000018992949,0.000014513919,0.00038554368],"genre_scores_gemma":[0.39671573,0.00007728183,0.6019706,0.0005454729,0.00016511479,0.0001488919,0.0001895052,0.00004661199,0.0001407767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979494,0.0007026732,0.0003481041,0.000500288,0.00007389877,0.0004256409],"domain_scores_gemma":[0.9994693,0.000031776457,0.00006722397,0.00035910003,0.00002014222,0.000052502943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011961556,0.00018385262,0.0002497747,0.0002002399,0.000049222916,0.000005453336,0.0002840791,0.00014331711,0.0000827547],"category_scores_gemma":[0.00016051924,0.0002110748,0.00008585919,0.0003162826,0.00004557114,0.0000010758637,0.0004081305,0.0002963019,0.0000014287187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024202329,0.000043786727,0.0022108632,0.0000073598285,0.000014884949,0.000047452813,0.00004743715,0.0118859485,0.98109055,0.00009030234,0.00006305452,0.0044741817],"study_design_scores_gemma":[0.00061319803,0.00020377287,0.00061405875,0.0000026976504,0.000005596236,0.000031686788,0.00008807109,0.0009733804,0.9806646,0.0004144671,0.016158596,0.00022985607],"about_ca_topic_score_codex":0.000049072733,"about_ca_topic_score_gemma":0.000017441598,"teacher_disagreement_score":0.11671682,"about_ca_system_score_codex":0.00004016531,"about_ca_system_score_gemma":0.000042590695,"threshold_uncertainty_score":0.86073804},"labels":[],"label_agreement":null},{"id":"W4285275163","doi":"10.7202/1089787ar","title":"CRISPR Gene-Therapy: A Critical Review of Ethical Concerns and a Proposal for Public Decision-Making","year":2022,"lang":"en","type":"review","venue":"Canadian Journal of Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Novo Nordisk Fonden; Novo Nordisk","keywords":"CRISPR; Mainstream; Autonomy; Engineering ethics; Beneficence; Ethical decision; Psychology; Political science; Biology; Gene; Social psychology; Genetics; Law; Engineering","score_opus":0.12499716911388493,"score_gpt":0.4566454827008989,"score_spread":0.33164831358701397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285275163","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000060757725,0.9893773,0.007969053,0.0014609199,0.00050025433,0.0004156972,0.0002407555,0.0000016618377,0.000028248933],"genre_scores_gemma":[0.00027055852,0.99091816,0.007354251,0.00083787466,0.00049099454,0.000026016562,0.00004078016,0.000054630036,0.0000067462],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980617,0.00020978859,0.0008761474,0.0002691831,0.00024860422,0.00033456724],"domain_scores_gemma":[0.99790543,0.00054946716,0.00035555923,0.00028615416,0.00043794763,0.00046541894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017534739,0.00026770213,0.001004173,0.00021263066,0.00012979026,0.00004535661,0.00042061525,0.0007332133,0.00009999705],"category_scores_gemma":[0.004993904,0.00023334938,0.00053545914,0.00017087716,0.00041267715,0.0000035787032,0.000062573396,0.0011920118,2.7878403e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001859299,0.000016555852,0.000004255469,0.038131315,0.00028742218,0.00005715116,0.00006711576,0.000001733912,0.000032218795,0.0018819971,0.00649314,0.9530085],"study_design_scores_gemma":[0.00015555175,0.00046127776,3.5229584e-7,0.017818645,0.00025899214,0.00058608514,0.000030444473,0.0000033897138,0.000048554753,0.0003057334,0.98009646,0.00023449809],"about_ca_topic_score_codex":0.00004705376,"about_ca_topic_score_gemma":0.0007012553,"teacher_disagreement_score":0.9736033,"about_ca_system_score_codex":0.00006585807,"about_ca_system_score_gemma":0.0085045695,"threshold_uncertainty_score":0.99711627},"labels":[],"label_agreement":null},{"id":"W4285492049","doi":"10.1007/s12033-022-00532-x","title":"A Simple, Affordable, and Rapid Visual CRISPR-Based Field Test for Sex Determination of Earlier Porcine Embryos and Pork Products","year":2022,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Natural Science Foundation of China","keywords":"CRISPR; Testis determining factor; Amplicon; Biology; Loop-mediated isothermal amplification; Computational biology; Polymerase chain reaction; Genetics; Gene; Molecular biology; DNA; Y chromosome","score_opus":0.004154699113478225,"score_gpt":0.265972950722156,"score_spread":0.2618182516086778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285492049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83707315,0.0019315302,0.15919647,0.0011790291,0.000053537864,0.00047678946,0.00003204744,0.000028220138,0.000029255649],"genre_scores_gemma":[0.99349225,0.00006367706,0.0058589983,0.00026670107,0.000024924984,0.000097402844,0.00008972152,0.000025697333,0.00008063371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991482,0.000020700454,0.0001785169,0.00036625497,0.00007954546,0.00020678074],"domain_scores_gemma":[0.999565,0.000026721715,0.000068060675,0.00026007468,0.000046330028,0.000033808512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014638396,0.00014050622,0.00016759364,0.00012951938,0.00008394438,0.0000072168555,0.00010872186,0.00018266863,0.000008528201],"category_scores_gemma":[0.00024349663,0.00015557073,0.000037896632,0.00014118491,0.00007377446,0.0000016990494,0.00018916542,0.000109840905,1.01280904e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051257684,0.000059545455,0.00046543652,0.00008249362,0.000016052427,0.0000061824085,0.000011744977,0.00008687453,0.98090166,0.00005419215,0.00021025514,0.018054334],"study_design_scores_gemma":[0.0007235182,0.002111588,0.00028288044,0.0000042353136,0.000027643362,0.000041774452,0.00007182002,0.0028098936,0.98278254,0.000088666115,0.010887479,0.00016793273],"about_ca_topic_score_codex":0.000008004533,"about_ca_topic_score_gemma":0.000003367976,"teacher_disagreement_score":0.15641911,"about_ca_system_score_codex":0.0000062016566,"about_ca_system_score_gemma":0.000036603724,"threshold_uncertainty_score":0.63439906},"labels":[],"label_agreement":null},{"id":"W4285588609","doi":"10.1186/s12284-022-00585-1","title":"Whole-Genome Sequencing of Rice Mutant Library Members Induced by N-Methyl-N-Nitrosourea Mutagenesis of Fertilized Egg Cells","year":2022,"lang":"en","type":"article","venue":"Rice","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Biology; Genetics; Mutant; Genome; Mutagenesis; Gene; Point mutation; Functional genomics; Whole genome sequencing; Mutation; Reverse genetics; Forward genetics; Genomics; Computational biology","score_opus":0.009137663876754364,"score_gpt":0.24739578671706428,"score_spread":0.23825812284030992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285588609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99606836,0.0017681774,0.0007315087,0.000049886217,0.00013357552,0.00016630934,0.00033038275,0.000019601324,0.0007321803],"genre_scores_gemma":[0.9981479,0.000069928064,0.0008788596,0.00010050469,0.0000457917,0.000023439765,0.00019304619,0.00004322013,0.00049730355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987765,0.00008655435,0.0003384491,0.000306953,0.00021596436,0.00027557727],"domain_scores_gemma":[0.9993101,0.00003076031,0.00015220449,0.0003784021,0.00003495241,0.0000935833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019246245,0.00017273883,0.00025205957,0.00007759778,0.00006867531,0.000008312784,0.00031226542,0.00008909441,0.000103441176],"category_scores_gemma":[0.000027950255,0.00018785955,0.00013002146,0.00030667955,0.000031630254,0.000006018296,0.0002722349,0.00012780071,0.0000018860197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076857126,0.000049899096,0.00003231054,0.000105137835,0.000076715325,0.0000046897107,0.00023006175,0.0027225304,0.99631846,0.0000022401503,0.0002628074,0.000118305295],"study_design_scores_gemma":[0.00045077183,0.00021347163,0.000590215,0.000005561813,0.00004546437,0.000010247197,0.00054742256,0.00016876543,0.9903016,0.0000072847542,0.0074608806,0.00019832437],"about_ca_topic_score_codex":0.00011499075,"about_ca_topic_score_gemma":0.0000013340023,"teacher_disagreement_score":0.007198073,"about_ca_system_score_codex":0.000027724202,"about_ca_system_score_gemma":0.00010598612,"threshold_uncertainty_score":0.766069},"labels":[],"label_agreement":null},{"id":"W4285591957","doi":"10.1007/s12033-022-00533-w","title":"Enhancement of Escherichia coli Ribonuclease R Cytosine-Sensitive Activity by Single Amino Acid Substitution","year":2022,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Education and Child Care","funders":"National Key Research and Development Program of China; Innovative Research Group Project of the National Natural Science Foundation of China","keywords":"RNase P; RNA; Cytosine; Nuclease; Biology; Biochemistry; Ribonuclease; Exoribonuclease; Escherichia coli; RNase H; Mutant; Molecular biology; Enzyme; DNA; Gene","score_opus":0.004950248348581017,"score_gpt":0.23462530988217056,"score_spread":0.22967506153358955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285591957","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8403651,0.0008018226,0.15798232,0.00030769137,0.000120110504,0.00019051017,0.000059672457,0.000032601307,0.00014019634],"genre_scores_gemma":[0.9981981,0.000053021395,0.0012915657,0.0001497764,0.000016396389,0.000043936718,0.00012811199,0.000025977588,0.00009311275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892753,0.000062716164,0.00017806712,0.0003993029,0.00015766274,0.00027469415],"domain_scores_gemma":[0.99937344,0.0000036207591,0.00010318649,0.00043006454,0.00004187538,0.000047817808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010409293,0.00017708853,0.00019393343,0.00008366496,0.00009877113,0.0000058804335,0.00020721085,0.00020501211,0.000028532031],"category_scores_gemma":[0.000047062167,0.00021476927,0.000091008194,0.0002249028,0.00015873644,0.0000021738076,0.0003474253,0.00019635615,0.0000033543338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009150153,0.00023000991,0.00001620771,0.000012919872,0.000059657617,0.0000151180075,0.000013097416,0.0003133826,0.99654025,0.00023306714,0.00034983866,0.0021249799],"study_design_scores_gemma":[0.00041434,0.0006941646,0.00006512894,0.0000034730638,0.000025778018,0.000017941362,0.000046131267,0.0002074566,0.9798781,0.000016450764,0.01842315,0.00020783904],"about_ca_topic_score_codex":0.000026215728,"about_ca_topic_score_gemma":0.0000047520016,"teacher_disagreement_score":0.15783302,"about_ca_system_score_codex":0.000049578357,"about_ca_system_score_gemma":0.000040455667,"threshold_uncertainty_score":0.8758037},"labels":[],"label_agreement":null},{"id":"W4285684828","doi":"10.24918/cs.2022.17","title":"Workshop Report: Summer 2020 Virtual CRISPR in the Classroom","year":2022,"lang":"en","type":"article","venue":"CourseSource","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"CRISPR; Curriculum; Computer science; Cas9; Multimedia; World Wide Web; Biology; Genetics; Psychology; Pedagogy","score_opus":0.010553951051439026,"score_gpt":0.30484115318942084,"score_spread":0.2942872021379818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285684828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837303,0.0030614764,0.007675367,0.0017798193,0.00040848277,0.00022332733,0.000018528555,0.000019943824,0.0030827448],"genre_scores_gemma":[0.99537784,0.000029996158,0.00006323097,0.0007888862,0.00030875197,0.000063719664,0.00010760357,0.000021165348,0.0032388305],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99902403,0.00008225873,0.00017494861,0.00027922733,0.00020614322,0.00023337148],"domain_scores_gemma":[0.9994135,0.00002721676,0.000044223616,0.00045841455,0.000016645745,0.000039992377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039057073,0.000114482165,0.00009229732,0.000028742223,0.00012262752,0.00002068513,0.00032938056,0.00005192931,0.00009908752],"category_scores_gemma":[0.0000828582,0.0001016815,0.0000730204,0.00016684599,0.00003477649,0.0000012006186,0.00018658668,0.00023668261,0.0000062170852],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002456992,0.0005634458,0.032104187,0.000024739467,0.00016248932,0.0013936227,0.0030911418,0.14029968,0.18036288,0.00040248886,0.6212571,0.020092523],"study_design_scores_gemma":[0.0003641594,0.00014074983,0.0044220723,0.0000039055762,0.000019893077,0.00044912644,0.004661017,0.0004029307,0.0036296,0.000019086168,0.9856695,0.00021795284],"about_ca_topic_score_codex":0.000011679287,"about_ca_topic_score_gemma":0.000029484914,"teacher_disagreement_score":0.3644124,"about_ca_system_score_codex":0.000014813673,"about_ca_system_score_gemma":0.00003932337,"threshold_uncertainty_score":0.41464514},"labels":[],"label_agreement":null},{"id":"W4285724937","doi":"10.4103/1673-5374.346541","title":"Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers","year":2022,"lang":"en","type":"review","venue":"Neural Regeneration Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Recombinase; Cre recombinase; Computational biology; Gene targeting; Gene knockout; Gene; Biology; Gene knockin; Gene deletion; Computer science; Genetics; Transgene; Genetically modified mouse","score_opus":0.3378395576406995,"score_gpt":0.4976372603918285,"score_spread":0.15979770275112898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285724937","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019573203,0.9791685,0.016092774,0.000088330315,0.0008243412,0.0031872748,0.0003223296,0.000014892552,0.00010582273],"genre_scores_gemma":[0.00023508258,0.9883155,0.00059643976,0.0000051552765,0.0009818358,0.003320365,0.0029834863,0.000106916035,0.003455226],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99664545,0.00056502747,0.0007516917,0.00076058233,0.00071200996,0.000565231],"domain_scores_gemma":[0.99827605,0.00030147258,0.00015277501,0.0006381398,0.0004470893,0.00018446607],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021041976,0.0002783911,0.00061977474,0.00045651273,0.0002857832,0.000080997874,0.0005023389,0.00039448656,0.000026745718],"category_scores_gemma":[0.0005917162,0.0002591102,0.0004155287,0.00043961004,0.00012989642,0.000008235648,0.0002373671,0.00048079604,0.000001549046],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012401189,0.00016024384,1.2589496e-7,0.009792419,0.00014083889,0.0000032634819,0.000035842204,0.0061362763,0.02021732,0.0010357761,0.114142485,0.8482114],"study_design_scores_gemma":[0.00044032844,0.0010388171,9.072449e-8,0.00022837639,0.000036718095,0.000019077583,0.00005393025,0.010551147,0.0017840978,0.000030677857,0.9856067,0.00021007132],"about_ca_topic_score_codex":0.000035820303,"about_ca_topic_score_gemma":0.0000071572267,"teacher_disagreement_score":0.8714642,"about_ca_system_score_codex":0.00013082598,"about_ca_system_score_gemma":0.00051488023,"threshold_uncertainty_score":0.9999861},"labels":[],"label_agreement":null},{"id":"W4286213409","doi":"10.1177/01622439221112460","title":"Does “Precision” Matter? A Q Study of Public Interpretations of Gene Editing in Agriculture","year":2022,"lang":"en","type":"article","venue":"Science Technology & Human Values","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Genome British Columbia","keywords":"Futures contract; Vision; Sociotechnical system; Emerging technologies; Agriculture; Sociology; Environmental ethics; Epistemology; Political science; Business; Computer science; Knowledge management; Ecology","score_opus":0.008642227105489836,"score_gpt":0.3086798748723742,"score_spread":0.30003764776688435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286213409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987149,0.0001590861,0.0005346571,0.00011596944,0.00013406196,0.00016820371,0.0000070122824,0.000015651525,0.00015041762],"genre_scores_gemma":[0.9992313,0.0000034515278,0.0005982698,0.000010051067,0.000018697372,0.000052019695,0.0000052311807,0.000005177802,0.000075839394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906194,0.000032682627,0.00024416466,0.00028830784,0.00019422363,0.00017867847],"domain_scores_gemma":[0.99947816,0.0000065563377,0.00009419557,0.00031448944,0.00008676245,0.000019839605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045472765,0.00007627726,0.00012435456,0.0005168707,0.00022251956,0.000008481834,0.0005921742,0.000043914908,0.00003037605],"category_scores_gemma":[0.00009731876,0.000056173914,0.00002818521,0.00090183434,0.00042569367,0.000006306587,0.0004496689,0.00011987324,4.4501243e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000015072511,0.00015604681,0.0629265,0.0000051530988,0.000007807523,8.555651e-7,0.00077924854,0.00094369316,0.93413717,0.00010076659,0.000049305378,0.0008919474],"study_design_scores_gemma":[0.00040410704,0.0008167874,0.05272082,0.000013196453,0.000011466252,0.000011492585,0.035428204,0.00012536043,0.9089683,0.0011375956,0.00021695967,0.00014569631],"about_ca_topic_score_codex":0.000018404442,"about_ca_topic_score_gemma":0.00009379775,"teacher_disagreement_score":0.034648955,"about_ca_system_score_codex":0.00001863737,"about_ca_system_score_gemma":0.00003402509,"threshold_uncertainty_score":0.22907057},"labels":[],"label_agreement":null},{"id":"W4286449069","doi":"10.1016/j.cell.2022.06.046","title":"Synthetic chromosomes, genomes, viruses, and cells","year":2022,"lang":"en","type":"review","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"International Development Research Centre; National Institute of Allergy and Infectious Diseases; J. Craig Venter Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Genome; Synthetic biology; Genetics; Genomics; Nucleic acid; Computational biology; DNA; Gene","score_opus":0.018717564930609575,"score_gpt":0.2983897260159045,"score_spread":0.27967216108529497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286449069","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000030320865,0.9970037,0.00009527445,0.0000013815625,0.00032607754,0.0002858637,0.000085058535,0.000015148165,0.002157185],"genre_scores_gemma":[0.000030515354,0.99708146,0.00022218798,0.000036287885,0.00022520135,0.00007151427,0.00022359799,0.000083612744,0.0020256443],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988381,0.000054082695,0.00024984108,0.0005092504,0.000094920106,0.00025380537],"domain_scores_gemma":[0.9992784,0.000022965707,0.00008574952,0.0005034967,0.0000070114215,0.00010236393],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010629809,0.000321851,0.0005236022,0.00006137939,0.00006885693,0.000025177818,0.00024818492,0.00020779653,0.00029653002],"category_scores_gemma":[0.00000775121,0.00031062533,0.00020931048,0.000080903264,0.000037372847,7.2406397e-7,0.0003131298,0.00020011995,0.00003569771],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029926146,0.00006345726,7.695887e-7,0.011031782,0.00012404282,0.000030184994,0.000025278805,0.000025172487,0.0092751505,0.0000071243167,0.0048707593,0.9745433],"study_design_scores_gemma":[0.00008208703,0.00007232479,1.4410803e-7,0.00015454464,0.00019237105,0.000044771412,0.0000070288065,0.0000020793102,0.004331799,0.0000020959446,0.9947633,0.0003474107],"about_ca_topic_score_codex":0.0000038982557,"about_ca_topic_score_gemma":0.0000016862039,"teacher_disagreement_score":0.9898926,"about_ca_system_score_codex":0.000022930406,"about_ca_system_score_gemma":0.00013104756,"threshold_uncertainty_score":0.9999346},"labels":[],"label_agreement":null},{"id":"W4286492057","doi":"10.1089/crispr.2021.0132","title":"Allele-Specific Inactivation of an Autosomal Dominant Epidermolysis Bullosa Simplex Mutation Using CRISPR-Cas9","year":2022,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire Sainte-Justine; Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Université Laval; Université du Québec à Chicoutimi","funders":"","keywords":"Epidermolysis bullosa simplex; Keratin 5; Keratin 14; Biology; CRISPR; Mutant; Genetics; Keratin; Epidermolysis bullosa; Cas9; Allele; Gene; Molecular biology; Transgene","score_opus":0.020219615846895755,"score_gpt":0.3168270845139955,"score_spread":0.29660746866709975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286492057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8892239,0.00091559876,0.10921272,0.00022885989,0.0002261461,0.00012229235,0.000013646518,0.0000063839443,0.000050483915],"genre_scores_gemma":[0.99725646,0.000116275696,0.002036601,0.00005338955,0.00040704856,0.000009418455,0.000049790982,0.00002962634,0.000041363928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986065,0.00024170289,0.00039645017,0.00020760241,0.00029481246,0.0002529071],"domain_scores_gemma":[0.9992119,0.000026301654,0.00024741277,0.00032060719,0.000114845374,0.0000789406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070813403,0.00015102273,0.00017540986,0.00009812874,0.0005002376,0.00003874961,0.00029017587,0.00005502205,0.00018034596],"category_scores_gemma":[0.00005509452,0.00012715797,0.00013862806,0.00016360363,0.000051100564,0.000012618744,0.00013318234,0.00027819112,9.819565e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015035731,0.00007568544,0.00004157762,0.000008461181,0.00006437061,0.00004339889,0.0004471992,0.06145819,0.9307225,0.000053350897,0.0005412273,0.00639373],"study_design_scores_gemma":[0.00093635876,0.0005123119,0.0015916736,0.000008821189,0.0000871113,0.004469086,0.003126957,0.016378095,0.95961267,0.00039408955,0.0126092015,0.00027364556],"about_ca_topic_score_codex":0.000032275217,"about_ca_topic_score_gemma":0.0000041163257,"teacher_disagreement_score":0.108032614,"about_ca_system_score_codex":0.000060316204,"about_ca_system_score_gemma":0.00007548894,"threshold_uncertainty_score":0.51853514},"labels":[],"label_agreement":null},{"id":"W4286579129","doi":"10.1007/978-1-0716-2513-2_12","title":"Identification of Drug Resistance Mechanisms Using Genome-Wide CRISPR-Cas9 Screens","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Gene knockout; Cas9; Genome editing; Biology; Computational biology; Gene; Guide RNA; Genome; Genetics; Drug discovery; Genetic screen; Bioinformatics; Phenotype","score_opus":0.015090187576528776,"score_gpt":0.39418847624096975,"score_spread":0.37909828866444095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286579129","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13381833,0.0024001386,0.8631673,0.000069011454,0.00020675707,0.00019426605,0.000025986483,0.000008875978,0.000109377506],"genre_scores_gemma":[0.42936492,0.00004778981,0.57000935,0.00015414594,0.000023574068,0.00005123259,0.000069748676,0.000032048425,0.00024716803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99790305,0.0007859351,0.0004650411,0.00046125732,0.00010214234,0.0002825842],"domain_scores_gemma":[0.9991805,0.000040887677,0.00016131069,0.00051926536,0.000055849872,0.00004217755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015379379,0.00016029816,0.00024103043,0.0001635367,0.00008090914,0.000006129113,0.0003421029,0.000099498684,0.000030430008],"category_scores_gemma":[0.0002483487,0.00019012237,0.00011232065,0.00027466338,0.000070905924,0.0000016466217,0.0003286736,0.0001645484,5.409272e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038842416,0.000033269698,0.0003274561,0.000021113885,0.00003129593,0.0000059522886,0.00006262082,0.007682625,0.9902146,0.001156592,0.000018957642,0.0004066708],"study_design_scores_gemma":[0.000290125,0.00006171378,0.00036833753,0.0000038536778,0.00002083233,0.000010432017,0.00016495994,0.0008415199,0.9892329,0.0038514135,0.0049481844,0.0002057312],"about_ca_topic_score_codex":0.000021522987,"about_ca_topic_score_gemma":0.00001711805,"teacher_disagreement_score":0.2955466,"about_ca_system_score_codex":0.000039295697,"about_ca_system_score_gemma":0.000049938397,"threshold_uncertainty_score":0.77529657},"labels":[],"label_agreement":null},{"id":"W4286685058","doi":"10.1002/bit.28190","title":"From functional genomics of vero cells to CRISPR‐based genomic deletion for improved viral production rates","year":2022,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Vero cell; Biology; CRISPR; ISG15; Virology; Functional genomics; Gene; Virus; Viral replication; Genetics; Genome; Genomics","score_opus":0.006331138571204507,"score_gpt":0.2351738186657961,"score_spread":0.22884268009459158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286685058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75374275,0.00052226835,0.24450348,0.0004378616,0.00043323927,0.00023314302,0.000097292075,0.000029023946,9.564399e-7],"genre_scores_gemma":[0.9879459,0.000043853623,0.011487364,0.00005501429,0.00017799786,0.00008404842,0.00015855975,0.00002037604,0.000026852831],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993522,0.000007077315,0.0001519378,0.0002950897,0.000035288827,0.00015838872],"domain_scores_gemma":[0.99972427,0.000007919169,0.00003684952,0.00017629223,0.000024234507,0.00003041328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000922411,0.00011605454,0.000115203715,0.00010854944,0.0000830295,0.000005127304,0.00009176134,0.00013155922,0.0000060874668],"category_scores_gemma":[0.000019624067,0.00013387408,0.00004585618,0.000077642224,0.000029381696,0.000002026555,0.000107728556,0.00008810257,4.3482427e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012470332,0.000019098608,0.000032953336,0.000017945376,0.00003596633,1.5122517e-7,0.000013410359,0.03844631,0.95950043,0.00002793969,0.00021719905,0.0015638897],"study_design_scores_gemma":[0.000325339,0.00035307257,0.00040392886,0.00000294954,0.000020966565,0.0000037685518,0.00006256041,0.011052781,0.968174,0.000022566826,0.019431653,0.00014642652],"about_ca_topic_score_codex":0.000012289631,"about_ca_topic_score_gemma":0.0000041452267,"teacher_disagreement_score":0.2342032,"about_ca_system_score_codex":0.000026404845,"about_ca_system_score_gemma":0.000024267276,"threshold_uncertainty_score":0.5459227},"labels":[],"label_agreement":null},{"id":"W4287921975","doi":"10.3389/fgeed.2022.892769","title":"Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases","year":2022,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"China Scholarship Council","keywords":"Genome editing; Transcription activator-like effector nuclease; CRISPR; Zinc finger nuclease; Biology; Nuclease; Genome engineering; Computational biology; Cas9; Genetics; Palindrome; Genome; Gene","score_opus":0.017250560352576938,"score_gpt":0.3153868773273218,"score_spread":0.29813631697474485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4287921975","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00064100954,0.9760231,0.021477453,0.0000024257313,0.00034147248,0.0010585134,0.0004452446,0.000004655685,0.000006176777],"genre_scores_gemma":[0.00070575974,0.98886657,0.008908578,0.0000031379054,0.00042285447,0.00062540703,0.00040261165,0.00003713259,0.000027969745],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990638,0.000030944215,0.00040589014,0.00027354012,0.000077788725,0.00014802371],"domain_scores_gemma":[0.9993538,0.000032335232,0.0002513384,0.00030796634,0.000020984011,0.000033576525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000093278984,0.00018665587,0.00045042913,0.000090199035,0.000048946808,0.000006111227,0.0001602016,0.00008513288,0.000003683791],"category_scores_gemma":[0.000039252023,0.00015114734,0.0001842463,0.000075879936,0.000049965194,0.0000013573319,0.000058015892,0.000040778392,2.840101e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011939221,0.00007922725,0.00008475249,0.0021026367,0.00015510953,6.3057445e-7,0.00005389367,0.00007791118,0.0013182089,9.460732e-7,0.0001189546,0.99599576],"study_design_scores_gemma":[0.00025383904,0.0004296689,0.0000781581,0.00015701653,0.00049250736,0.0000020644836,0.00014334354,0.00023306491,0.0020594634,0.0000125714805,0.9959622,0.00017610923],"about_ca_topic_score_codex":0.000010452196,"about_ca_topic_score_gemma":9.4359e-7,"teacher_disagreement_score":0.99584323,"about_ca_system_score_codex":0.00004916416,"about_ca_system_score_gemma":0.00005646393,"threshold_uncertainty_score":0.61636096},"labels":[],"label_agreement":null},{"id":"W4288423205","doi":"10.1126/science.abo3471","title":"Molecular recorders to track cellular events","year":2022,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Track (disk drive); Computational biology; Computer science; Biology","score_opus":0.005378074050114524,"score_gpt":0.28114841546509645,"score_spread":0.2757703414149819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288423205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98254836,0.000252401,0.015819972,0.0001673404,0.00032701454,0.00010116494,0.000004246356,0.00000962457,0.0007698938],"genre_scores_gemma":[0.9980052,0.000004648396,0.0011788534,0.00037292956,0.00002754944,0.000023065277,0.000005122743,0.000007789457,0.00037482995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991859,0.0000123177915,0.0000696554,0.00029012663,0.00022387289,0.00021811844],"domain_scores_gemma":[0.99961305,0.0000013979574,0.0000123128175,0.0002545368,0.000024180028,0.000094551746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025805048,0.00006039234,0.000041642223,0.0000534779,0.00016346177,0.000010586188,0.00035863285,0.000012215156,0.000047206933],"category_scores_gemma":[0.000040751853,0.00006810689,0.000030169374,0.00032254553,0.000037256515,0.0000016120938,0.00026147004,0.000048882168,0.00001137095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004412769,0.000011252061,0.00020907958,0.0000013843272,0.0000016936128,0.0000023496568,0.000042981905,0.015264226,0.98222595,0.000017258679,0.00023564747,0.0019837667],"study_design_scores_gemma":[0.000093703835,0.00016460709,0.0009651534,0.0000011343734,0.0000021414344,0.000006640965,0.0001155117,0.00028503657,0.92370087,0.000046354944,0.07449598,0.00012289172],"about_ca_topic_score_codex":0.0000046429755,"about_ca_topic_score_gemma":0.000001722036,"teacher_disagreement_score":0.07426033,"about_ca_system_score_codex":0.000017736775,"about_ca_system_score_gemma":0.00006818726,"threshold_uncertainty_score":0.27773184},"labels":[],"label_agreement":null},{"id":"W4288442480","doi":"10.1038/s41598-022-17200-4","title":"Prime editor-mediated correction of a pathogenic mutation in purebred dogs","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Rural Development Administration","keywords":"Purebred; Prime (order theory); Mutation; Virology; Medicine; Genetics; Biology; Gene; Mathematics; Combinatorics; Crossbreed","score_opus":0.003777221936423837,"score_gpt":0.2467690605871432,"score_spread":0.24299183865071938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288442480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781316,0.0002878865,0.000855905,0.000011591206,0.020376017,0.00016126253,0.000004442771,0.000009954458,0.0001613682],"genre_scores_gemma":[0.99858624,0.0000027635563,0.00009185843,0.0000057371085,0.00019846666,0.00003614342,0.000350875,0.000008460923,0.00071943743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990259,0.00003401424,0.0002650495,0.0003251211,0.00022408432,0.00012583262],"domain_scores_gemma":[0.9994883,0.0000053114723,0.000120289755,0.00030123803,0.00005433196,0.000030528307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006248648,0.00006179798,0.00007651255,0.00010547864,0.000073218784,0.000014173377,0.00006035771,0.000037285907,0.0000412632],"category_scores_gemma":[0.00012516533,0.00006936191,0.000047287333,0.000301985,0.00003539728,0.0000024985386,0.00007535056,0.000063286054,0.0000010428583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001109632,0.000042991775,0.0027056534,0.000005806884,0.0000053625495,0.000029469582,0.00012954311,0.0077381385,0.9803734,3.389882e-7,0.0077854875,0.0011727229],"study_design_scores_gemma":[0.00031672756,0.00017788705,0.009810028,0.00000927914,0.000011203484,0.00026626486,0.00028112123,0.0029398778,0.9079438,0.000102078615,0.077943794,0.00019792805],"about_ca_topic_score_codex":0.000029319075,"about_ca_topic_score_gemma":0.000037176615,"teacher_disagreement_score":0.072429575,"about_ca_system_score_codex":0.000022646005,"about_ca_system_score_gemma":0.00009700814,"threshold_uncertainty_score":0.28284967},"labels":[],"label_agreement":null},{"id":"W4288446620","doi":"10.1038/s41551-022-00911-4","title":"Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors","year":2022,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of General Medical Sciences; National Eye Institute; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; National Science Foundation; National Institutes of Health; U.S. Department of Health and Human Services; Howard Hughes Medical Institute","keywords":"Base (topology); Genome; In vivo; Biology; Encoding (memory); Computer science; Computational biology; Genetics; Gene; Mathematics; Neuroscience","score_opus":0.004183485916595092,"score_gpt":0.23763680454202538,"score_spread":0.23345331862543028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288446620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737843,0.0035868443,0.017895339,0.0003787557,0.0034786407,0.00041950497,0.00015859792,0.00018831865,0.000109667446],"genre_scores_gemma":[0.9943102,0.000010823042,0.0036126703,0.00015213102,0.0016612242,0.00003709778,0.000101761616,0.000073333234,0.00004074517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978919,0.00005090606,0.00036452612,0.0005079216,0.0005858226,0.0005989458],"domain_scores_gemma":[0.99921626,0.00013097432,0.000090660746,0.000263688,0.00004858448,0.00024984477],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042560493,0.00033441646,0.0003395313,0.0002322771,0.00012897894,0.000028299122,0.00029154375,0.0003101024,0.00017549204],"category_scores_gemma":[0.00052047195,0.00032386882,0.000111463465,0.0006152169,0.00005250052,0.00000460105,0.00018604388,0.00086532446,0.0000010273169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007273722,0.00017780543,0.00023653953,0.00003441475,0.00006219898,0.000076946606,0.00008255681,0.36785257,0.6298867,0.0000021747078,0.0014019845,0.00011339937],"study_design_scores_gemma":[0.0084726345,0.0017305737,0.0016921705,0.00033038837,0.00014222582,0.00023978733,0.00068266405,0.4251713,0.46389583,0.0000032208677,0.09569832,0.001940905],"about_ca_topic_score_codex":0.000020714167,"about_ca_topic_score_gemma":0.000006128047,"teacher_disagreement_score":0.16599084,"about_ca_system_score_codex":0.00019560242,"about_ca_system_score_gemma":0.000069470436,"threshold_uncertainty_score":0.9999213},"labels":[],"label_agreement":null},{"id":"W4288885884","doi":"10.1016/j.ydbio.2022.07.008","title":"Optimizing CRISPR/Cas9-based gene manipulation in echinoderms","year":2022,"lang":"en","type":"article","venue":"Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Sleep Foundation; National Institutes of Health; University of Guelph; National Science Foundation","keywords":"CRISPR; Biology; Cas9; Computational biology; Genome editing; Morpholino; Computer science; Gene; Genetics; Zebrafish","score_opus":0.012536589714427997,"score_gpt":0.2987205842312306,"score_spread":0.2861839945168026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288885884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9735068,0.00045315642,0.024932407,0.0000845587,0.00025919775,0.00015434613,0.000018086153,0.000018993955,0.00057244307],"genre_scores_gemma":[0.98296714,0.000015609365,0.01571865,0.00038746165,0.000040334617,0.00006515181,0.00071174355,0.000017024937,0.00007689626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916184,0.000051499177,0.00019140787,0.00029842136,0.000059868496,0.00023696772],"domain_scores_gemma":[0.9998016,0.000007436522,0.000032996948,0.000112619615,0.000010042071,0.00003534245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014999215,0.00012199334,0.000105856845,0.00009794237,0.000101413556,0.0000061116352,0.00014336423,0.00006993306,0.000106013125],"category_scores_gemma":[0.000013498912,0.00013716426,0.000037869388,0.000112433176,0.000021748825,0.0000015022995,0.00018620618,0.000104636754,0.000006346922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004891708,0.00004475998,0.02756123,0.0000056516606,0.000014435633,0.000009222767,0.00010865724,0.020493064,0.94922066,0.00004206892,0.00014672944,0.0023046052],"study_design_scores_gemma":[0.0012704022,0.00024014957,0.025569117,0.0000042667343,0.0000057026273,0.00008189006,0.0003136358,0.004279106,0.93720645,0.00007741577,0.030482108,0.00046975916],"about_ca_topic_score_codex":0.00002938098,"about_ca_topic_score_gemma":0.000044213095,"teacher_disagreement_score":0.030335378,"about_ca_system_score_codex":0.00006802172,"about_ca_system_score_gemma":0.00006531769,"threshold_uncertainty_score":0.55933964},"labels":[],"label_agreement":null},{"id":"W4289260450","doi":"10.21203/rs.3.rs-1825493/v1","title":"oFlowSeq: A multiplexed quantitative approach to identify genes affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome Canada","funders":"National Human Genome Research Institute; National Institute of Mental Health; National Institutes of Health","keywords":"CRISPR; Biology; Locus (genetics); Indel; Computational biology; Cell type; Gene; Organoid; Cas9; Genetics; Cell; Genotype; Single-nucleotide polymorphism","score_opus":0.07036425520618693,"score_gpt":0.44677472142969804,"score_spread":0.3764104662235111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289260450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9670629,0.0060492954,0.02261405,0.000044564124,0.0011151809,0.0020847358,0.0002608265,0.00006663619,0.0007018165],"genre_scores_gemma":[0.97308517,0.00027507593,0.022977484,0.00003168356,0.0008721388,0.0002819194,0.001608328,0.00016428022,0.0007039427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99543804,0.00064584194,0.00045296492,0.0013969885,0.001047137,0.0010190341],"domain_scores_gemma":[0.997715,0.0001080306,0.000114355236,0.0010802099,0.0006468722,0.0003355477],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014685782,0.0004913073,0.00045681436,0.00052649685,0.0004502032,0.00020088967,0.0007858094,0.00044150025,0.00014432239],"category_scores_gemma":[0.0005738972,0.0005371019,0.00024368675,0.0008575205,0.000079800244,0.000006267724,0.003723203,0.001284172,0.000024090565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017143747,0.00027870794,0.0017888366,0.0011534343,0.00015879139,0.000017634702,0.0011653155,0.118093394,0.8730517,0.000013589813,0.0037689738,0.00033815764],"study_design_scores_gemma":[0.0019055385,0.0019981794,0.0054038605,0.00039253986,0.00015145753,0.000033069533,0.014437364,0.050613604,0.89773786,0.0000720968,0.024999505,0.0022549226],"about_ca_topic_score_codex":0.00044352296,"about_ca_topic_score_gemma":0.000037448797,"teacher_disagreement_score":0.06747979,"about_ca_system_score_codex":0.0003003745,"about_ca_system_score_gemma":0.0004624816,"threshold_uncertainty_score":0.99970806},"labels":[],"label_agreement":null},{"id":"W4289550496","doi":"10.1186/s12951-022-01570-y","title":"Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing","year":2022,"lang":"en","type":"review","venue":"Journal of Nanobiotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Computer science; Biology; Genetics; Gene","score_opus":0.037807894466995735,"score_gpt":0.38673522089357276,"score_spread":0.34892732642657703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289550496","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000072898954,0.9609618,0.036943518,0.00011031297,0.0012549359,0.00049254386,0.00011544984,0.000017205672,0.000031297524],"genre_scores_gemma":[0.00021609862,0.9935185,0.0047632847,0.000038634378,0.0008901279,0.00006385279,0.00015299449,0.00008435001,0.00027217303],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99815744,0.0000683682,0.0009316155,0.00031205278,0.00015437939,0.00037611878],"domain_scores_gemma":[0.9983509,0.0001278491,0.00087903556,0.00040895172,0.0001555931,0.00007766982],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004548781,0.00034591235,0.001047094,0.0005348813,0.00015923956,0.000019191666,0.000635371,0.0008231434,0.00005968487],"category_scores_gemma":[0.0006894443,0.00031589318,0.0008165086,0.00026789814,0.0000670413,0.0000042663264,0.00027069927,0.0006213585,0.0000033632364],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007296139,0.000104094004,9.14651e-7,0.0028295447,0.0009356278,0.000060508974,0.000034853314,0.00087972067,0.016481295,0.00020967599,0.003557497,0.9748333],"study_design_scores_gemma":[0.00035627958,0.0008075676,5.9783446e-7,0.00030835785,0.00044991646,0.0011044561,0.000056806977,0.000015611055,0.001357817,0.000046241905,0.9952174,0.0002789442],"about_ca_topic_score_codex":7.2630047e-7,"about_ca_topic_score_gemma":0.0000014320573,"teacher_disagreement_score":0.9916599,"about_ca_system_score_codex":0.00010218641,"about_ca_system_score_gemma":0.00039278922,"threshold_uncertainty_score":0.9999293},"labels":[],"label_agreement":null},{"id":"W4289837269","doi":"10.1101/2022.08.04.502727","title":"Quantitative assaying of SpCas9-NG with fluorescent reporters","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Agence Nationale de la Recherche","keywords":"Cas9; CRISPR; Endonuclease; Computational biology; Fluorescence; Biology; Genome editing; Chemistry; Molecular biology; Enzyme; Biochemistry; Gene","score_opus":0.011771423216785948,"score_gpt":0.2632442199010205,"score_spread":0.25147279668423456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289837269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97547376,0.002539362,0.020590508,0.00004510695,0.0006106527,0.00049321743,0.000156453,0.00006635937,0.000024582278],"genre_scores_gemma":[0.9857143,0.0002529724,0.0135789,0.00004592263,0.0001524921,0.00012400541,0.000002906292,0.00012137842,0.0000070858164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778193,0.00008524642,0.00050538016,0.0008657643,0.00036907787,0.0003926083],"domain_scores_gemma":[0.9979337,0.000019135758,0.00043840194,0.0011842389,0.00027552017,0.0001489938],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004634946,0.00043112508,0.00044608465,0.00015230633,0.000097337725,0.000044585096,0.0004025495,0.00026358504,0.000036434674],"category_scores_gemma":[0.00013554879,0.00045321483,0.00016459926,0.00022839675,0.00010428688,0.00000484243,0.000601821,0.00045578,0.0000022215986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010396943,0.00008000191,0.007942669,0.0003198579,0.00035386224,0.000060337814,0.00001327585,0.005675142,0.9852075,0.00008160446,0.00016021056,0.0000015886264],"study_design_scores_gemma":[0.00042096246,0.00036402588,0.033657815,0.00019353579,0.00014610542,1.08723775e-7,0.00002706893,0.00036707518,0.9609618,3.8039676e-7,0.003189605,0.0006715127],"about_ca_topic_score_codex":0.000041803753,"about_ca_topic_score_gemma":0.000003732999,"teacher_disagreement_score":0.025715146,"about_ca_system_score_codex":0.000079360056,"about_ca_system_score_gemma":0.00040171988,"threshold_uncertainty_score":0.999792},"labels":[],"label_agreement":null},{"id":"W4290599871","doi":"10.3390/ijms23158774","title":"Identification of Novel Regulators of Radiosensitivity Using High-Throughput Genetic Screening","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Canadian Nuclear Laboratories; University of Ottawa","funders":"Atomic Energy of Canada Limited","keywords":"Biology; CRISPR; Radioresistance; Computational biology; Radiosensitivity; DNA repair; Transcriptome; DNA damage; DNA microarray; RNA interference; Gene; Genome; Genetics; RNA; DNA; Gene expression; Medicine","score_opus":0.039383275667636566,"score_gpt":0.37698005490159026,"score_spread":0.3375967792339537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4290599871","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05545652,0.7421114,0.2014769,0.0000096662025,0.00079152005,0.00010045252,0.000039072627,0.0000014651812,0.000013022368],"genre_scores_gemma":[0.19381455,0.78389007,0.021987071,0.0000117688105,0.00023838722,0.000002128818,0.000020226926,0.000025947222,0.00000982291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99789864,0.00009117332,0.00091490755,0.00023077463,0.0007470277,0.00011746543],"domain_scores_gemma":[0.99809146,0.00003701538,0.0013863925,0.00018322324,0.00026097667,0.00004095657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076476444,0.00016316985,0.00048412697,0.00031960095,0.000039842354,0.000024930288,0.00074784603,0.00009154061,0.00000906898],"category_scores_gemma":[0.00016674181,0.00015151745,0.0004123336,0.00023603342,0.00017948341,0.000009472029,0.0001970239,0.00012767056,9.1139675e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023202161,0.0001627128,0.00004293197,0.0006707288,0.0008829719,0.00004530653,0.000060612532,0.07969766,0.48743924,0.00019400746,0.000020509666,0.4307601],"study_design_scores_gemma":[0.0022262193,0.0015484423,0.00056288415,0.00788479,0.0022429165,0.006115699,0.00040956898,0.006321039,0.68491447,0.00020690534,0.28586605,0.001701029],"about_ca_topic_score_codex":0.0000147918945,"about_ca_topic_score_gemma":0.0000010062755,"teacher_disagreement_score":0.42905906,"about_ca_system_score_codex":0.000034295183,"about_ca_system_score_gemma":0.0003161368,"threshold_uncertainty_score":0.6178702},"labels":[],"label_agreement":null},{"id":"W4291624725","doi":"10.1038/s41559-022-01841-9","title":"Competition and coevolution drive the evolution and the diversification of CRISPR immunity","year":2022,"lang":"en","type":"article","venue":"Nature Ecology & Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Centre National de la Recherche Scientifique; Agence Nationale de la Recherche; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Coevolution; CRISPR; Diversification (marketing strategy); Competition (biology); Immunity; Biology; Evolutionary biology; Genetics; Business; Ecology; Gene; Immune system; Marketing","score_opus":0.002411629883117856,"score_gpt":0.23573189194780303,"score_spread":0.23332026206468517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291624725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97278404,0.0070309257,0.018059533,0.0012169357,0.00036272543,0.0003642294,0.000029784023,0.000010802767,0.00014100822],"genre_scores_gemma":[0.99932426,0.00021653133,0.000090585854,0.000078443416,0.00007634072,0.00005032248,0.00010119561,0.0000064031005,0.0000559233],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991394,0.00028798336,0.00014561364,0.00018956682,0.00011294885,0.00012444807],"domain_scores_gemma":[0.9995037,0.00006341182,0.000109007175,0.00021614088,0.00008816136,0.00001959698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005639809,0.00008955431,0.00010231144,0.000047591813,0.0005487887,0.0000061799274,0.00012702496,0.00016032078,0.000010672016],"category_scores_gemma":[0.00011588881,0.00006779549,0.00004302527,0.00012046033,0.00033033077,0.0000055111536,0.00021914746,0.00035792342,5.419228e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019728253,0.0002945468,0.1640158,0.00010734279,0.000367991,0.0000011264004,0.0017629756,0.013178162,0.6118195,0.19838226,0.0064111045,0.0016863889],"study_design_scores_gemma":[0.0014562972,0.0002821703,0.98322576,0.0000040803807,0.00009526728,0.00006008022,0.0020479686,0.0047872937,0.003352053,0.0026018478,0.0019637623,0.00012342179],"about_ca_topic_score_codex":0.00010440483,"about_ca_topic_score_gemma":0.00014091135,"teacher_disagreement_score":0.81920993,"about_ca_system_score_codex":0.00009081238,"about_ca_system_score_gemma":0.000039976585,"threshold_uncertainty_score":0.42208943},"labels":[],"label_agreement":null},{"id":"W4291825011","doi":"10.1038/s41419-022-05146-4","title":"EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Epigenetics; Epigenome; Biology; CRISPR; Chromatin; Cancer; Triple-negative breast cancer; Computational biology; Cancer cell; Cancer research; Genetics; DNA methylation; Gene; Breast cancer; Gene expression","score_opus":0.018693686496371893,"score_gpt":0.30313275053716016,"score_spread":0.2844390640407883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291825011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9505894,0.013067193,0.03515538,0.00017470332,0.00020408769,0.0003489133,0.00025764867,0.00003381352,0.00016884645],"genre_scores_gemma":[0.99683845,0.00016204061,0.001397883,0.00048971176,0.00017524183,0.00030942747,0.0001897443,0.00003926856,0.00039826098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986843,0.00004474053,0.00021406797,0.00048460023,0.00020576619,0.00036652925],"domain_scores_gemma":[0.99892235,0.00002321531,0.00004124652,0.0003898438,0.000036472782,0.0005868801],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348147,0.00021718457,0.00016026036,0.00008279739,0.00033368965,0.000060312315,0.00018745865,0.00004138132,0.00024193455],"category_scores_gemma":[0.000042922344,0.00023698981,0.000104438244,0.00011361488,0.00003493556,0.0000043608284,0.00020159868,0.00010561441,0.000005300579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011517539,0.0003867567,0.030453626,0.00056399807,0.00007822587,0.000111689515,0.00059001875,0.1605841,0.76963264,0.000102584665,0.015194783,0.021149829],"study_design_scores_gemma":[0.006224689,0.0012888529,0.14727534,0.000113120936,0.0002836692,0.000016883689,0.0015961917,0.014490474,0.57206136,0.0005668888,0.25348863,0.0025939029],"about_ca_topic_score_codex":0.00005846797,"about_ca_topic_score_gemma":0.000010565338,"teacher_disagreement_score":0.23829384,"about_ca_system_score_codex":0.000026483263,"about_ca_system_score_gemma":0.00012654177,"threshold_uncertainty_score":0.9664164},"labels":[],"label_agreement":null},{"id":"W4292263339","doi":"10.1101/2022.08.17.504245","title":"Epigenetic-focused CRISPR/Cas9 screen identifies ASH2L as a regulator of glioblastoma cell survival","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Biology; Chromatin; Epigenetics; Cancer research; Regulator; Cell cycle; Glioma; CRISPR; Cancer; Genetics; Gene","score_opus":0.007983654586258559,"score_gpt":0.2465706843009541,"score_spread":0.23858702971469556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292263339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854668,0.005333774,0.006003987,0.00005712833,0.0016706701,0.0007255446,0.0005380672,0.00012886025,0.00007519177],"genre_scores_gemma":[0.99561393,0.00060347014,0.002602385,0.00005899626,0.0005899951,0.00017304934,0.000004593605,0.00023991353,0.000113651],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962537,0.00020462499,0.00082333403,0.0013638707,0.00065418694,0.00070027256],"domain_scores_gemma":[0.996524,0.00003842248,0.00049681397,0.002197343,0.00042606372,0.0003173554],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006654117,0.00074618176,0.0007597636,0.00029509966,0.00017243318,0.00011549199,0.0010749309,0.00066109456,0.0002271496],"category_scores_gemma":[0.00020880958,0.0009048565,0.0004234046,0.00039463444,0.00016702047,0.000008657442,0.0016865996,0.0006133238,0.000027884551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013805246,0.00015684737,0.0020007768,0.00044724272,0.00024251237,0.00003269585,0.000013908201,0.0017152673,0.99443567,0.00006023656,0.0007525839,0.000004200123],"study_design_scores_gemma":[0.00070172927,0.00034603942,0.019614935,0.00009716483,0.00016188179,5.7838466e-8,0.000017109724,0.00013071748,0.96527785,0.000002677348,0.012738135,0.000911702],"about_ca_topic_score_codex":0.00012440674,"about_ca_topic_score_gemma":0.00001688529,"teacher_disagreement_score":0.029157827,"about_ca_system_score_codex":0.00008776377,"about_ca_system_score_gemma":0.0005918498,"threshold_uncertainty_score":0.99934024},"labels":[],"label_agreement":null},{"id":"W4292291677","doi":"10.1139/bcb-2021-0506","title":"Community-led risk analysis of direct-to-consumer whole-genome sequencing","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Whole genome sequencing; Personalized medicine; Genetic testing; Personal genomics; Population; Business; Genome; Biology; Genetics; Gene; Medicine","score_opus":0.007395546901354082,"score_gpt":0.2653692803292171,"score_spread":0.257973733427863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292291677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99389774,0.0027750821,0.0005979887,0.000022305136,0.000055938777,0.000077082135,0.0005678226,0.000011170162,0.0019948785],"genre_scores_gemma":[0.9978147,0.00016698746,0.0002680461,0.00008842293,0.00003861763,0.000030099123,0.00090508256,0.000012171967,0.0006758688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904454,0.00015922634,0.0002220941,0.00030128515,0.00005630866,0.00021654586],"domain_scores_gemma":[0.9992945,0.00003121656,0.00009330061,0.0004497674,0.000035823432,0.000095389856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003513014,0.0001533493,0.00026268844,0.00009329441,0.00022613972,0.0000059393537,0.0002364892,0.00011081258,0.000064460655],"category_scores_gemma":[0.000051634255,0.00016417581,0.00012344222,0.00031384596,0.00008128032,8.2715576e-7,0.00039215625,0.00021378543,0.0000012409192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043094708,0.00004079762,0.00544346,0.0000264509,0.000312871,7.85302e-7,0.00014997236,0.0028846574,0.99048394,0.0000018639656,0.0000839045,0.0005282313],"study_design_scores_gemma":[0.00027951796,0.00024288055,0.0016444032,0.0000017260859,0.0003207217,0.0000046715872,0.00073144666,0.0001809164,0.9533371,0.0000069807697,0.043014817,0.00023484934],"about_ca_topic_score_codex":0.0001078161,"about_ca_topic_score_gemma":0.000014168135,"teacher_disagreement_score":0.042930912,"about_ca_system_score_codex":0.000020694759,"about_ca_system_score_gemma":0.00004024756,"threshold_uncertainty_score":0.6694895},"labels":[],"label_agreement":null},{"id":"W4292676385","doi":"","title":"Introduction to gene flow modelling and co-existence","year":2003,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact","funders":"","keywords":"Flow (mathematics); Gene flow; Computer science; Gene; Mechanics; Biology; Physics; Genetics","score_opus":0.010612692490032981,"score_gpt":0.2512843494667901,"score_spread":0.24067165697675713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292676385","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20653285,0.0017515271,0.785721,0.0024188932,0.00019220832,0.0002284058,0.000029270397,0.000032427826,0.0030934198],"genre_scores_gemma":[0.6278105,0.0023534338,0.36112505,0.0001493297,0.00025902624,0.00007203817,0.0008797705,0.000065159256,0.007285691],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981606,0.000561285,0.00023778282,0.00068226614,0.00014319883,0.00021487183],"domain_scores_gemma":[0.9980765,0.00004257156,0.00009026659,0.0011137322,0.0005338236,0.0001431105],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013553889,0.00021271541,0.00017592523,0.00006946485,0.00012460393,0.0001193113,0.00031123156,0.00020805515,0.000021687343],"category_scores_gemma":[0.00029411362,0.00024858565,0.00007378108,0.00009123988,0.0000626527,0.0000035537605,0.0004249747,0.00021904873,0.000008946321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051457748,0.00036063924,0.00072567555,0.0004135013,0.0002180814,0.000004414565,0.004579622,0.20613804,0.725933,0.004087725,0.010573683,0.046914153],"study_design_scores_gemma":[0.0002399736,0.0000010531661,0.0002472498,0.00018932216,0.000029352024,0.0000223166,0.00003969977,0.047624677,0.8753481,0.00037674097,0.07543219,0.00044934195],"about_ca_topic_score_codex":0.00007829536,"about_ca_topic_score_gemma":0.00007944368,"teacher_disagreement_score":0.42459592,"about_ca_system_score_codex":0.000023591187,"about_ca_system_score_gemma":0.00007045915,"threshold_uncertainty_score":0.99999666},"labels":[],"label_agreement":null},{"id":"W4292836745","doi":"10.1080/21645698.2022.2111946","title":"Public perception of plant gene technologies worldwide in the light of food security","year":2022,"lang":"en","type":"article","venue":"GM crops & food","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Food security; China; Product (mathematics); Biotechnology; European union; Genetically modified organism; Perception; Genome editing; Genetically modified crops; Emerging technologies; State (computer science); Political science; Biology; Business; Genome; Agriculture; Gene; International trade; Genetics; Transgene; Computer science; Ecology","score_opus":0.011080187870119078,"score_gpt":0.23853304258120392,"score_spread":0.22745285471108484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292836745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99668777,0.0018932178,0.00027140952,0.00045018416,0.00006322478,0.0001447586,0.00011783147,0.000013462003,0.0003581337],"genre_scores_gemma":[0.9995625,0.000086442036,0.00016902565,0.000025181364,0.000023078093,0.000044030952,0.00007016077,0.000008388739,0.0000111712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993376,0.0000408742,0.00017948508,0.00015990899,0.0001324416,0.00014968631],"domain_scores_gemma":[0.9995892,0.0000068748755,0.00005571702,0.00031228477,0.000024756728,0.000011132455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019666235,0.00008322662,0.000108305176,0.0000780591,0.000044160166,0.0000060905268,0.0002948806,0.000057056946,0.00001611706],"category_scores_gemma":[0.00003534458,0.000069626505,0.000060898616,0.00019190884,0.0000402552,0.0000017845942,0.00019586935,0.00012005217,3.2437825e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003657521,0.00013253735,0.001663865,0.000037449165,0.00004059641,0.0000014726907,0.00069082074,0.00025873777,0.99365973,0.00057521125,0.00052700005,0.0023759915],"study_design_scores_gemma":[0.0005651489,0.0020488924,0.006425979,0.000008959961,0.000019141158,0.000050461196,0.0050079967,0.000065641696,0.94799083,0.00083390437,0.03678207,0.00020096173],"about_ca_topic_score_codex":0.000009384739,"about_ca_topic_score_gemma":0.00010798355,"teacher_disagreement_score":0.0456689,"about_ca_system_score_codex":0.0000102887125,"about_ca_system_score_gemma":0.000025906145,"threshold_uncertainty_score":0.28392866},"labels":[],"label_agreement":null},{"id":"W4293030248","doi":"10.3390/ijms23179538","title":"Vitelline Membrane Protein 26 Mutagenesis, Using CRISPR/Cas9, Results in Egg Collapse in Plutella xylostella","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Fujian Agriculture and Forestry University; National Natural Science Foundation of China","keywords":"Vitelline membrane; Biology; Plutella; Mutant; Yolk; Gene; Frameshift mutation; Molecular biology; Genetics; Oocyte; Exon; Embryo; Botany","score_opus":0.015035101018940457,"score_gpt":0.32388177519346945,"score_spread":0.308846674174529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293030248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993066,0.002019103,0.0036253848,0.000472191,0.00045652306,0.00012549548,0.0000136978815,0.0000028411444,0.000218737],"genre_scores_gemma":[0.9963154,0.00012006493,0.0032262865,0.00014254065,0.00011673883,0.000004565624,0.000005134227,0.000013482929,0.000055790504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998234,0.00011984778,0.00052734144,0.00024807156,0.0006708837,0.00019988042],"domain_scores_gemma":[0.9994707,0.000018538996,0.00021111501,0.00011662918,0.00012673267,0.000056282348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011335857,0.00011914986,0.00015002444,0.00040003183,0.000055262237,0.00004824367,0.00067333947,0.00004484347,0.000020833679],"category_scores_gemma":[0.00013719754,0.00012037628,0.00009071352,0.00035383442,0.00007480675,0.000010823454,0.0002106365,0.00016370819,7.174858e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015999348,0.000067481815,0.00040656884,0.0000035190126,0.000018002307,0.00030599305,0.00009836142,0.27139845,0.726736,0.00002443582,0.000018361068,0.0007628275],"study_design_scores_gemma":[0.0012851916,0.0003416063,0.0003021941,0.0000494686,0.0000063508655,0.00044396953,0.00042903973,0.0062055443,0.98811144,0.00008248002,0.002564328,0.00017838347],"about_ca_topic_score_codex":0.00006112949,"about_ca_topic_score_gemma":0.000043701435,"teacher_disagreement_score":0.26519293,"about_ca_system_score_codex":0.00007518497,"about_ca_system_score_gemma":0.00022129757,"threshold_uncertainty_score":0.49088022},"labels":[],"label_agreement":null},{"id":"W4293062666","doi":"10.1111/dgd.12802","title":"Involvement of strawberry notch homologue 1 in neurite outgrowth of cortical neurons","year":2022,"lang":"en","type":"article","venue":"Development Growth & Differentiation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Neurite; Biology; Conditional gene knockout; Axon; Neuroscience; Cerebral cortex; Knockout mouse; Axon guidance; Cortical neurons; Neuron; CRISPR; Cell biology; Gene; Cortex (anatomy); Genetics; Phenotype; In vitro","score_opus":0.009361668599201789,"score_gpt":0.24893886088674205,"score_spread":0.23957719228754026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293062666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928603,0.00010284822,0.006569795,0.00003212712,0.00015183013,0.00016543841,0.000015043075,0.0000057870757,0.000096828786],"genre_scores_gemma":[0.9989698,0.000027800248,0.00052250293,0.000030853193,0.000015854446,0.000050033042,0.00033125063,0.000012901102,0.000039015926],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99897,0.00006123377,0.00038547805,0.00021348496,0.00020765001,0.00016216232],"domain_scores_gemma":[0.9996772,0.000012389943,0.000096465796,0.00013710785,0.000042838215,0.000034002325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014188892,0.000110414316,0.00014811808,0.0001177977,0.00004619399,0.0000037679529,0.00013783886,0.000042385047,0.00003368508],"category_scores_gemma":[0.000029505294,0.00012422526,0.000045825873,0.00013751637,0.000022544435,0.0000027611143,0.00018514987,0.00010435382,4.826993e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006414127,0.0003527214,0.16517724,0.0001012466,0.00004732143,0.0000034927386,0.00058899657,0.00080783165,0.8315033,0.00029374985,0.00008570531,0.00097427785],"study_design_scores_gemma":[0.00042722514,0.00011785017,0.606274,0.0000066353305,0.000009064962,0.0000021578794,0.000090363465,0.00023066746,0.3925533,0.000031706222,0.00015466784,0.000102381775],"about_ca_topic_score_codex":0.000019124504,"about_ca_topic_score_gemma":0.00003228142,"teacher_disagreement_score":0.44109675,"about_ca_system_score_codex":0.00002443243,"about_ca_system_score_gemma":0.000064483436,"threshold_uncertainty_score":0.50657594},"labels":[],"label_agreement":null},{"id":"W4293334925","doi":"10.1016/j.jconrel.2022.08.042","title":"LNP-mediated delivery of CRISPR RNP for wide-spread in vivo genome editing in mouse cornea","year":2022,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Incisive Genetics (Canada); BC Children's Hospital; University of British Columbia","funders":"","keywords":"Genome editing; CRISPR; Ribonucleoprotein; Cas9; Guide RNA; Computational biology; Genome; Cornea; Ex vivo; Cell biology; Biology; In vivo; RNA; Genetics; Gene; Neuroscience","score_opus":0.005604476592208423,"score_gpt":0.2513862389881965,"score_spread":0.2457817623959881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293334925","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99087703,0.0038120952,0.004448562,0.0001401971,0.00024118535,0.00035118908,0.000062906285,0.0000025265633,0.00006430073],"genre_scores_gemma":[0.99881345,0.00028876244,0.00031122725,0.00013712805,0.00021286849,0.000037075843,0.000013733712,0.000021262631,0.00016448481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986519,0.000086961176,0.00072066614,0.00013693821,0.0001813689,0.00022212126],"domain_scores_gemma":[0.9991431,0.00013993568,0.00035578554,0.00013531955,0.00014463498,0.00008122792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000650288,0.0001250327,0.00044329805,0.00021776302,0.000033960274,0.00000749568,0.00018753903,0.00007101582,0.000036297577],"category_scores_gemma":[0.00061041635,0.00012075261,0.00022464423,0.000115541516,0.000020394571,0.0000052737128,0.00006215213,0.00021924253,2.2896843e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035914648,0.00017865193,0.0017345138,0.000036952144,0.000092191636,0.00004780135,0.00010462637,0.070272356,0.92294276,0.0000047188123,0.00068394665,0.00031002559],"study_design_scores_gemma":[0.14086114,0.0063440613,0.005831793,0.00018777791,0.00033001354,0.00026332153,0.0034916466,0.044016037,0.7489159,0.00016484637,0.04844696,0.001146513],"about_ca_topic_score_codex":0.00002105271,"about_ca_topic_score_gemma":0.000053272903,"teacher_disagreement_score":0.17402686,"about_ca_system_score_codex":0.000045465888,"about_ca_system_score_gemma":0.00014215239,"threshold_uncertainty_score":0.49241486},"labels":[],"label_agreement":null},{"id":"W4293446047","doi":"10.1007/s10265-022-01409-5","title":"Metabolic pathway genes for editing to enhance multiple disease resistance in plants","year":2022,"lang":"en","type":"article","venue":"Journal of Plant Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Gene; Genome; Plant disease resistance; Genetics; Indel; Pathogen; Secondary metabolite; Metabolic pathway; Genome editing; Biotechnology; Resistance (ecology); Computational biology; Single-nucleotide polymorphism; Genotype; Ecology","score_opus":0.026298559938939637,"score_gpt":0.37510210570550123,"score_spread":0.3488035457665616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293446047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842086,0.011408108,0.0030143268,0.00036374852,0.00026225165,0.00026270136,0.00042727697,0.0000019603392,0.000051038514],"genre_scores_gemma":[0.9969657,0.00032832462,0.0015138022,0.00003774567,0.0005776788,0.000060838698,0.000037637117,0.000013109525,0.0004651543],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988355,0.00009656559,0.00023956901,0.00015676416,0.00036942397,0.00030219197],"domain_scores_gemma":[0.9994688,0.00009114411,0.00005463305,0.00013419882,0.00010286197,0.00014833958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013659818,0.000068127105,0.00012668858,0.00018222239,0.00011653111,0.000016827069,0.0002607418,0.000022841712,0.000007994188],"category_scores_gemma":[0.00043457054,0.00006519231,0.000060031,0.00012590003,0.000012919821,0.0000031053996,0.0001388819,0.0002124471,7.0288144e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012825083,0.00008605131,0.0032191684,0.00005152532,0.000026661008,0.000103408725,0.00019358374,0.006319946,0.97395784,0.000029089164,0.011749938,0.0029803005],"study_design_scores_gemma":[0.00052593934,0.0002718351,0.005619376,0.000046261932,0.000003882282,0.000027427923,0.00035873725,0.00028067318,0.44456622,0.000063465835,0.54811203,0.00012411778],"about_ca_topic_score_codex":0.000007437535,"about_ca_topic_score_gemma":0.00015325042,"teacher_disagreement_score":0.5363621,"about_ca_system_score_codex":0.000025485515,"about_ca_system_score_gemma":0.00014163963,"threshold_uncertainty_score":0.26584652},"labels":[],"label_agreement":null},{"id":"W4293458012","doi":"10.3389/fmolb.2022.992664","title":"Editorial: Genetically mobile elements repurposed by nature and biotechnologists","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Molecular Biosciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; McGill University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Genetically modified organism; Computational biology; Genetics; Gene","score_opus":0.0014523985635282873,"score_gpt":0.2571431300229707,"score_spread":0.2556907314594424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293458012","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005138322,0.029265167,0.005839432,0.00005055224,0.9587901,0.0005062128,0.00029578872,0.000034866207,0.000079511105],"genre_scores_gemma":[0.00579836,0.01685344,0.029331015,0.00018047687,0.9442943,0.0005223621,0.0020848727,0.00015937175,0.00077580323],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968278,0.00009105743,0.0004051692,0.0012310954,0.000902264,0.00054262625],"domain_scores_gemma":[0.99903584,0.000018932707,0.0001534661,0.0005974573,0.00007495515,0.00011937268],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00056901865,0.0004096821,0.00036917828,0.00023318778,0.00013169143,0.000101072874,0.0009494703,0.0017824306,0.00001068427],"category_scores_gemma":[0.0006051825,0.0004244778,0.00010167631,0.00038821704,0.0003780121,0.0000047061685,0.0006255761,0.0010689467,5.278583e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002231065,0.000037826096,0.0001527441,0.000028998867,0.00003068534,0.000008720056,0.0000094871975,0.000055591503,0.14609842,0.0000017996307,0.85198486,0.0015685713],"study_design_scores_gemma":[0.0003903481,0.0004919667,0.000006213764,0.000018325813,0.0000225541,0.0000015105692,0.00011352013,0.00006468718,0.055313874,0.00005821603,0.94304734,0.0004714622],"about_ca_topic_score_codex":0.000020323783,"about_ca_topic_score_gemma":0.000008072525,"teacher_disagreement_score":0.09106248,"about_ca_system_score_codex":0.00006389175,"about_ca_system_score_gemma":0.00022157347,"threshold_uncertainty_score":0.9998207},"labels":[],"label_agreement":null},{"id":"W4293792660","doi":"10.3389/fgeed.2022.957289","title":"Bacterial genome reductions: Tools, applications, and challenges","year":2022,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"In silico; Chassis; Synthetic biology; Computer science; Genome; Genome editing; Computational biology; Biochemical engineering; Bacterial genome size; Function (biology); Genome engineering; Biology; Engineering; Genetics; Gene","score_opus":0.03201872707237976,"score_gpt":0.29834995995433167,"score_spread":0.26633123288195193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293792660","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000014984537,0.99404174,0.0029913986,0.000017984632,0.0017623255,0.000613972,0.0001275249,0.00001858669,0.0004114683],"genre_scores_gemma":[0.0000075210614,0.98816776,0.0046268594,0.000006366874,0.0047092782,0.0008017617,0.0014710355,0.00006790323,0.00014153642],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984898,0.000078194724,0.00041973096,0.0006050175,0.00010567967,0.00030160078],"domain_scores_gemma":[0.9993629,0.000017207267,0.00015420336,0.00038030322,0.000013694521,0.00007172546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002984967,0.0002962763,0.0005887243,0.00018619726,0.0001298572,0.000040359937,0.00026901034,0.0002414412,0.00003891005],"category_scores_gemma":[0.00006125817,0.00033692003,0.00013701807,0.00013765624,0.000045987494,0.000004822561,0.00026725174,0.00028376895,0.0000021520611],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002839288,0.00001805678,0.0000016898028,0.0030807818,0.00009725785,0.0000029078647,0.000062774176,0.00002795118,0.00014619132,0.000012831443,0.00034509946,0.99620163],"study_design_scores_gemma":[0.00010330226,0.000036847174,0.000009593702,0.00014055759,0.000084695894,0.000042936957,0.00035563097,0.0000019144586,0.000004730958,0.000012481366,0.9988944,0.00031290812],"about_ca_topic_score_codex":0.0000017734538,"about_ca_topic_score_gemma":0.0000016427358,"teacher_disagreement_score":0.9985493,"about_ca_system_score_codex":0.000080767815,"about_ca_system_score_gemma":0.000089382826,"threshold_uncertainty_score":0.99990827},"labels":[],"label_agreement":null},{"id":"W4293793014","doi":"10.3389/fgeed.2022.899331","title":"Towards social acceptability of genome-edited plants in industrialised countries? Emerging evidence from Europe, United States, Canada, Australia, New Zealand, and Japan","year":2022,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Horizon 2020 Framework Programme; Ministry of Business, Innovation and Employment; European Commission","keywords":"Legislation; Early adopter; Agriculture; Business; Political science; International trade; Economic growth; Geography; Economics; Marketing; Law","score_opus":0.03533733435957264,"score_gpt":0.3174208291352678,"score_spread":0.28208349477569516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293793014","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07303783,0.9209089,0.00032124633,0.000050607556,0.0025446976,0.00072298734,0.0023787,0.000010885805,0.000024091752],"genre_scores_gemma":[0.0021874579,0.9883055,0.00059879414,0.000028881419,0.0020948008,0.00004298545,0.006398171,0.00006967037,0.00027373608],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99717456,0.0002751044,0.0009884028,0.0006842508,0.00035110436,0.0005265763],"domain_scores_gemma":[0.99897707,0.0000685367,0.0004438328,0.00031459692,0.000050027935,0.00014593596],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061545667,0.00044155057,0.0011494923,0.00032654474,0.000080104146,0.00003629819,0.0004873565,0.00035452837,0.00021012373],"category_scores_gemma":[0.00038492575,0.0004981165,0.000101043486,0.0006373941,0.00007223444,0.000010241753,0.00034221556,0.0006628192,2.814585e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042700014,0.00012983642,0.0337261,0.008872238,0.0013193192,0.00019814892,0.006359519,0.007964251,0.00037273162,0.0000013346463,0.07647582,0.8641537],"study_design_scores_gemma":[0.0005356759,0.00004520619,0.0050468487,0.0004509475,0.00010893644,0.0000034690645,0.00073311693,0.000049165814,0.000026576723,0.0000026297882,0.99254745,0.00044999292],"about_ca_topic_score_codex":0.20664744,"about_ca_topic_score_gemma":0.036560267,"teacher_disagreement_score":0.9160716,"about_ca_system_score_codex":0.00032376527,"about_ca_system_score_gemma":0.0009979142,"threshold_uncertainty_score":0.99974704},"labels":[],"label_agreement":null},{"id":"W4293817200","doi":"10.1049/enb2.12024","title":"A curcumin direct protein biosensor for cell‐free prototyping","year":2022,"lang":"en","type":"article","venue":"Engineering Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kensington Health","funders":"Engineering and Physical Sciences Research Council","keywords":"Biosensor; Synthetic biology; Curcumin; Fluorescence; Substrate (aquarium); Protein engineering; Green fluorescent protein; Cell-free protein synthesis; Chemistry; Combinatorial chemistry; Escherichia coli; Biochemistry; Cofactor; Cell-free system; Directed evolution; Nanotechnology; Enzyme; Computational biology; Biology; Protein biosynthesis; Materials science; Gene","score_opus":0.005680150741722711,"score_gpt":0.2730709440880348,"score_spread":0.26739079334631205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293817200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8050757,0.0042510503,0.18450707,0.00030240635,0.001054354,0.0032173146,0.00033712198,0.00023226447,0.0010226893],"genre_scores_gemma":[0.9885341,0.000009006479,0.008389818,0.00004695661,0.0002947575,0.00182138,0.00016018176,0.00005261983,0.0006912038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903506,0.0000254992,0.00017262652,0.0003579156,0.000052736385,0.00035615286],"domain_scores_gemma":[0.9994885,0.000018126275,0.000036336984,0.00036934105,0.00003006926,0.00005767295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019448521,0.00017383121,0.00015752966,0.000077404606,0.000112201444,0.000008986358,0.00028154015,0.0000860223,0.000019853684],"category_scores_gemma":[0.00014179015,0.00019071788,0.000091819464,0.00012068359,0.000018507795,0.0000013614348,0.00023446757,0.00012075652,0.0000019014682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044425142,0.000032145188,0.00008191848,0.000058154525,0.000027299631,0.0000011652269,0.000029139688,0.008154717,0.9900766,0.00022952227,0.00070013525,0.00056474964],"study_design_scores_gemma":[0.0005939703,0.00053199957,0.00007143582,0.0000048944817,0.000007914676,0.0000111456875,0.000020937592,0.0021481095,0.6157501,0.000023581502,0.38058347,0.00025245492],"about_ca_topic_score_codex":0.0000057802617,"about_ca_topic_score_gemma":0.0000010106558,"teacher_disagreement_score":0.37988332,"about_ca_system_score_codex":0.00002266369,"about_ca_system_score_gemma":0.00003665993,"threshold_uncertainty_score":0.7777249},"labels":[],"label_agreement":null},{"id":"W4294218977","doi":"10.3389/fcell.2022.947769","title":"Recent advances in the use of CRISPR/Cas for understanding the early development of molecular gaps in glial cells","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Biology; Neurogenesis; Neuroscience; Nervous system; Central nervous system; Computational biology; Gene; Genetics","score_opus":0.041424762951526514,"score_gpt":0.322182335758336,"score_spread":0.28075757280680946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294218977","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0038530738,0.97593874,0.018870862,0.0000072605626,0.00040512826,0.0007895707,0.000042914606,0.0000014621128,0.000090999456],"genre_scores_gemma":[0.0031493774,0.98440665,0.012017059,0.00002859549,0.000013525804,0.00017687239,0.00017385217,0.000018468545,0.00001561196],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985284,0.00015559242,0.00062773604,0.00033987776,0.0000830891,0.0002652697],"domain_scores_gemma":[0.9995521,0.00010671159,0.00016570668,0.0001434133,0.000010491155,0.00002160958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043083547,0.00023913577,0.00056263007,0.00017560612,0.00004569628,0.0000077772365,0.00028415286,0.00019344162,0.0000051363695],"category_scores_gemma":[0.000036646714,0.00016533674,0.000087565146,0.00022766658,0.0001063747,0.0000041228022,0.0001720131,0.00018296143,1.2287244e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016753099,0.00016357283,0.0015072589,0.0034032736,0.000116504925,0.000010041737,0.002532262,0.00022691578,0.0043721413,0.00006221722,0.0006318404,0.98680645],"study_design_scores_gemma":[0.0004018459,0.00010510392,0.00003611033,0.0002249297,0.0000239253,0.0000049605114,0.0013568455,0.000006005654,0.007826632,0.00010281498,0.9896851,0.0002257268],"about_ca_topic_score_codex":0.000007448581,"about_ca_topic_score_gemma":0.000070817936,"teacher_disagreement_score":0.98905325,"about_ca_system_score_codex":0.00011295914,"about_ca_system_score_gemma":0.00020772126,"threshold_uncertainty_score":0.67422366},"labels":[],"label_agreement":null},{"id":"W4294433627","doi":"10.1093/ve/veac084","title":"Monotreme-specific conserved putative proteins derived from retroviral reverse transcriptase","year":2022,"lang":"en","type":"article","venue":"Virus Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science","keywords":"Reverse transcriptase; Monotreme; Biology; Computational biology; Genetics; RNA; Gene","score_opus":0.013240124646929792,"score_gpt":0.2517636701310333,"score_spread":0.2385235454841035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294433627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9148227,0.0026329511,0.08117584,0.00010163043,0.00031161774,0.0003227599,0.00044401712,0.000035293277,0.00015319748],"genre_scores_gemma":[0.996635,0.000074579824,0.0021202643,0.00010365997,0.00014254416,0.00011841998,0.00057102146,0.000023725333,0.00021074808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901825,0.00010420837,0.00017565422,0.00034357628,0.00015251084,0.00020581849],"domain_scores_gemma":[0.9995859,0.0000058196897,0.000050945346,0.00026107003,0.00003413812,0.00006212136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010415145,0.00013938904,0.000112083646,0.000043028052,0.0001915292,0.00001247823,0.00013294,0.00006412634,0.00016344302],"category_scores_gemma":[0.000020905032,0.00016370631,0.00009552847,0.00011265425,0.000043557033,0.00000437318,0.0000736639,0.00014073255,0.00001341284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022147332,0.000052365227,0.0003793696,0.000004089958,0.000033539447,0.0000064185438,0.0001634238,0.002275134,0.99335414,0.000037233523,0.002713204,0.0007595879],"study_design_scores_gemma":[0.0013065225,0.0004849033,0.01166528,0.0000056101385,0.00003083093,0.000008482819,0.0005711642,0.0014255812,0.9204601,0.00029830058,0.0633884,0.00035480375],"about_ca_topic_score_codex":0.00048431024,"about_ca_topic_score_gemma":0.00006094568,"teacher_disagreement_score":0.081812344,"about_ca_system_score_codex":0.00008666512,"about_ca_system_score_gemma":0.000052037554,"threshold_uncertainty_score":0.667575},"labels":[],"label_agreement":null},{"id":"W4295094517","doi":"10.20517/jtgg.2021.49","title":"Gene editing treatment strategies for retinitis pigmentosa assessed in Xenopus laevis carrying a mutant Rhodopsin allele","year":2022,"lang":"en","type":"article","venue":"Journal of Translational Genetics and Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Xenopus; Retinitis pigmentosa; Biology; Retinal degeneration; Rhodopsin; Mutant; Genome editing; Electroretinography; Genetics; Retinal; Gene; CRISPR; Biochemistry","score_opus":0.017539886184634697,"score_gpt":0.29869582469113526,"score_spread":0.28115593850650056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295094517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96993464,0.00639475,0.022844642,0.0002532633,0.00018714993,0.00019925833,0.00013892475,0.000001961555,0.0000453947],"genre_scores_gemma":[0.98185706,0.0013510946,0.016163068,0.000044722718,0.00042697712,0.000019524115,0.0000962815,0.000023177647,0.000018067814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990445,0.000037542355,0.00041590555,0.00016900829,0.00014775665,0.00018529128],"domain_scores_gemma":[0.9996178,0.000030369494,0.00012800242,0.00008549975,0.000073501404,0.00006482216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029429566,0.00013662534,0.00018927749,0.000089913556,0.00012171779,0.000042525622,0.00009920021,0.000050960818,0.000010519593],"category_scores_gemma":[0.000009137694,0.00014422937,0.000107658,0.000057186044,0.000020882248,0.000005189222,0.000026864582,0.00008885345,5.442449e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014982301,0.00007831349,0.0013227563,0.000022380302,0.00009759905,0.000012918839,0.00061420153,0.2620803,0.72947705,0.000064041385,0.000027283271,0.0060533453],"study_design_scores_gemma":[0.013383222,0.0064804545,0.011778187,0.00005260048,0.0003824183,0.0013766033,0.0068730987,0.040696494,0.735264,0.0034307803,0.17903791,0.0012442146],"about_ca_topic_score_codex":0.000009464575,"about_ca_topic_score_gemma":0.00005177983,"teacher_disagreement_score":0.22138382,"about_ca_system_score_codex":0.000043152228,"about_ca_system_score_gemma":0.00021867575,"threshold_uncertainty_score":0.5881503},"labels":[],"label_agreement":null},{"id":"W4295532939","doi":"10.1016/j.csbj.2022.09.012","title":"The application of genome-wide CRISPR-Cas9 screens to dissect the molecular mechanisms of toxins","year":2022,"lang":"en","type":"review","venue":"Computational and Structural Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Fundamental Research Funds for the Central Universities; Guangzhou Municipal Science and Technology Project; Terry Fox Foundation; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"CRISPR; Computational biology; Biology; Genome editing; Cas9; Genome; Gene; Genetics","score_opus":0.009805921734420315,"score_gpt":0.3055846665891806,"score_spread":0.2957787448547603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295532939","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020543768,0.71372986,0.28333136,0.00041597892,0.00010342628,0.00029930833,0.000051872972,0.000005363946,0.000008460323],"genre_scores_gemma":[0.07683329,0.9188177,0.0039852066,0.000073013805,0.00007702872,0.000034978537,0.00013431131,0.000028253993,0.000016223868],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99892765,0.00007111769,0.00044753373,0.00021724695,0.00017142175,0.00016503276],"domain_scores_gemma":[0.9992488,0.000091230846,0.00029952347,0.00024373183,0.00006938757,0.000047336645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021588139,0.0001941528,0.00036009977,0.0000981757,0.00027901717,0.00001835385,0.00049255847,0.00019914034,0.0000073011047],"category_scores_gemma":[0.000088466986,0.00011477588,0.00019998281,0.00019010526,0.00015544874,0.0000016420396,0.00028417454,0.00035772257,3.898159e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024425666,0.000011242365,0.000006326665,0.00040313616,0.00044836718,0.0000049130485,0.000031609572,0.009483969,0.008956571,0.012067828,0.00008302381,0.96847856],"study_design_scores_gemma":[0.0002532427,0.0005905389,0.00036383246,0.00016400758,0.00032393928,0.0015316511,0.00018447034,0.00083778513,0.006475139,0.014398847,0.9744569,0.0004196576],"about_ca_topic_score_codex":0.0000024185872,"about_ca_topic_score_gemma":0.000002879354,"teacher_disagreement_score":0.9743739,"about_ca_system_score_codex":0.000017371658,"about_ca_system_score_gemma":0.00008867429,"threshold_uncertainty_score":0.46804246},"labels":[],"label_agreement":null},{"id":"W4295677950","doi":"10.1016/j.schres.2022.09.011","title":"Complementary approaches involving monozygotic twins and single neuron genomics support postzygotic somatic mutations in schizophrenia","year":2022,"lang":"en","type":"letter","venue":"Schizophrenia Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Western University","keywords":"Somatic cell; Schizophrenia (object-oriented programming); Genetics; Biology; Genomics; Mutation; Neuroscience; Psychology; Genome; Gene; Psychiatry","score_opus":0.07360738226049937,"score_gpt":0.3295974274053709,"score_spread":0.25599004514487156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295677950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9493859,0.0043890546,0.00019400711,0.04275258,0.00049044564,0.0018348538,0.00037303148,0.000060881575,0.0005192535],"genre_scores_gemma":[0.9614381,0.0007710501,0.0074131256,0.014883028,0.0030649218,0.00060611655,0.010051176,0.00047548642,0.001296974],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99581754,0.000553372,0.0006414856,0.0011386654,0.0007474807,0.0011014403],"domain_scores_gemma":[0.9985544,0.00019858901,0.000111508874,0.00089474244,0.00007462069,0.00016615987],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000886683,0.0004988105,0.00048156374,0.0008086477,0.0003957328,0.00019973853,0.00074101443,0.0004456512,0.00023195898],"category_scores_gemma":[0.00013918441,0.0005817971,0.0001440737,0.0004274467,0.00027434411,0.000013483033,0.0012061723,0.00259065,0.000025843237],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029466974,0.0013260604,0.005129593,0.0055769808,0.001296325,0.0032116987,0.0035447292,0.0118475305,0.43546632,0.0003953858,0.5052775,0.023981186],"study_design_scores_gemma":[0.023612818,0.01091323,0.02995011,0.0007696373,0.0007422135,0.0020233633,0.0064144204,0.0270179,0.040615648,0.0073358626,0.841521,0.009083776],"about_ca_topic_score_codex":0.00016483436,"about_ca_topic_score_gemma":0.00039488132,"teacher_disagreement_score":0.39485067,"about_ca_system_score_codex":0.00022447134,"about_ca_system_score_gemma":0.00046660344,"threshold_uncertainty_score":0.99971044},"labels":[],"label_agreement":null},{"id":"W4295812271","doi":"10.3791/64209","title":"CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts","year":2022,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Zebrafish; Genome editing; Cas9; Biology; Gene knockin; Computational biology; Gene; Model organism; Forward genetics; Genetics; Genetic screen; Phenotype","score_opus":0.014399663409183746,"score_gpt":0.4146239785933647,"score_spread":0.40022431518418095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295812271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945444,0.0037394494,0.00045533193,0.00007567185,0.00081189413,0.00015502263,0.000008600073,0.000004354066,0.00020526155],"genre_scores_gemma":[0.99876064,0.00014193426,0.00048679803,0.00016435707,0.00022456014,0.000024130817,0.000022257696,0.000026195208,0.00014913848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985894,0.00012359065,0.0005283402,0.00018433756,0.00031053438,0.00026382232],"domain_scores_gemma":[0.9995265,0.000017778799,0.00015033346,0.00015757476,0.000046045334,0.00010179402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040002394,0.00014190497,0.00025550276,0.00021224136,0.000041336407,0.000016106771,0.00021067167,0.00006730771,0.00015534011],"category_scores_gemma":[0.00009451771,0.00014953686,0.00010433087,0.00019623175,0.000016278265,0.000007416434,0.00015608287,0.00022181822,0.0000027275842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042447407,0.0004471789,0.0033391563,0.000008765085,0.00003812913,0.00009726316,0.00061687216,0.0019023969,0.9836929,0.0000031616776,0.009037966,0.00039177766],"study_design_scores_gemma":[0.0059501515,0.0009769663,0.00770239,0.00005010496,0.000010909246,0.00012643088,0.00085205,0.0004448121,0.91391695,0.000023525563,0.06963478,0.0003109255],"about_ca_topic_score_codex":0.000022708311,"about_ca_topic_score_gemma":0.000010036045,"teacher_disagreement_score":0.06977591,"about_ca_system_score_codex":0.00007221816,"about_ca_system_score_gemma":0.00008154045,"threshold_uncertainty_score":0.6097936},"labels":[],"label_agreement":null},{"id":"W4296027240","doi":"10.1158/2159-8290.cd-21-0865","title":"Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer","year":2022,"lang":"en","type":"article","venue":"Cancer Discovery","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Terry Fox Research Institute; Instituto de Salud Carlos III; Canadian Institutes of Health Research; National Cancer Institute; Generalitat de Catalunya; Dr. Herbert and Nicole Wertheim Family Foundation; Breast Cancer Research Foundation","keywords":"Epigenetics; Biology; Breast cancer; Lineage (genetic); Cancer; Cancer research; Epigenesis; Genetics; Cell biology; DNA methylation; Gene; Gene expression","score_opus":0.011120265219738289,"score_gpt":0.2992731074032845,"score_spread":0.2881528421835462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296027240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98481315,0.0124260625,0.0016390104,0.00022465776,0.0002861394,0.00017084536,0.00039522778,0.000006915888,0.000038001574],"genre_scores_gemma":[0.9971035,0.001982612,0.00006587971,0.00005209781,0.00022361086,0.0001356457,0.00007235667,0.000023576527,0.0003407147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991676,0.00003472589,0.00018924207,0.00029752514,0.00014163219,0.0001692368],"domain_scores_gemma":[0.99961674,0.000007886589,0.00007998595,0.00020777236,0.00004022054,0.000047394115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009762721,0.00013827551,0.00015462766,0.00003949296,0.00008072474,0.000019393954,0.00012698083,0.0000564073,0.00006487688],"category_scores_gemma":[0.000007424724,0.00013400863,0.00006135026,0.00010161788,0.00007259464,0.000008259607,0.00020553163,0.000098943776,1.7008702e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093539136,0.00005918075,0.042141482,0.0001220902,0.00008150108,0.000001410671,0.00016164141,0.0058927387,0.94436306,0.000024550412,0.00024138772,0.0068174126],"study_design_scores_gemma":[0.00040950923,0.000114023205,0.26367936,0.000048378744,0.000057908066,0.00002462013,0.00015985136,0.00029744417,0.73345006,0.00004218324,0.001466397,0.00025026198],"about_ca_topic_score_codex":0.0003104401,"about_ca_topic_score_gemma":0.00018101321,"teacher_disagreement_score":0.22153787,"about_ca_system_score_codex":0.000030381363,"about_ca_system_score_gemma":0.00011433951,"threshold_uncertainty_score":0.54647136},"labels":[],"label_agreement":null},{"id":"W4296999084","doi":"10.3389/fviro.2022.972156","title":"Predicted cellular interactors of the endogenous retrovirus-K protease enzyme","year":2022,"lang":"en","type":"article","venue":"Frontiers in Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Winnipeg","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Interactome; Biology; Proteases; Cell biology; Endogenous retrovirus; Retrovirus; Proteome; Neurodegeneration; Protease; Carcinogenesis; Computational biology; Genetics; Gene; Enzyme; Genome; Biochemistry","score_opus":0.0058151619484506515,"score_gpt":0.2190333479415712,"score_spread":0.21321818599312053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296999084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892154,0.0013271953,0.007581239,0.00005987812,0.0012011204,0.00029832055,0.000048889033,0.000006933318,0.0002610696],"genre_scores_gemma":[0.9989936,0.000019161347,0.0004699596,0.00012832243,0.000060488837,0.00008168806,0.000036546895,0.000016455424,0.00019380442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914545,0.00013971463,0.00019783358,0.00021494713,0.00010035343,0.00020169663],"domain_scores_gemma":[0.9995363,0.0000052733444,0.00006804743,0.0003474492,0.000013069364,0.000029872388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404052,0.0000989016,0.00013991431,0.00006505821,0.000058023805,0.0000021441099,0.00029814104,0.00007453153,0.00004695848],"category_scores_gemma":[0.000058890306,0.00008947683,0.0000775803,0.00012460056,0.00007977696,0.000001168863,0.0002929896,0.00020426135,3.109602e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020241526,0.000082536266,0.07650334,0.000015022432,0.00004922281,0.000009565714,0.00024019487,0.0056101438,0.91283345,0.0000092372875,0.0038181702,0.0006267358],"study_design_scores_gemma":[0.0011148207,0.00089302287,0.016758498,0.0000050170497,0.000030550662,0.000050042272,0.00039029442,0.0015321729,0.91534185,0.00013148032,0.06352719,0.00022506883],"about_ca_topic_score_codex":0.00002531113,"about_ca_topic_score_gemma":0.000006262377,"teacher_disagreement_score":0.059744835,"about_ca_system_score_codex":0.000026424152,"about_ca_system_score_gemma":0.00004582665,"threshold_uncertainty_score":0.3648759},"labels":[],"label_agreement":null},{"id":"W4297207040","doi":"10.1101/2022.09.26.509570","title":"Efficient CRISPR/Cas9 mediated large insertions using long single-stranded oligonucleotide donors in <i>C. elegans</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"CRISPR; Cas9; Oligonucleotide; Biology; Computational biology; DNA; Template; Genetics; Exonuclease; Computer science; Gene; Polymerase","score_opus":0.011272730488400105,"score_gpt":0.25254198116333043,"score_spread":0.24126925067493032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297207040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800266,0.0021314872,0.015368729,0.00006818063,0.001100472,0.00071123196,0.0004369379,0.00014229627,0.000014076457],"genre_scores_gemma":[0.9966875,0.00026038752,0.0021228348,0.0002034194,0.0003695201,0.00014604688,0.000010218984,0.00019470998,0.0000053982367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996562,0.00017341084,0.0007352449,0.0012279078,0.00038706264,0.0009143682],"domain_scores_gemma":[0.99799633,0.000030628144,0.00025785516,0.0012378824,0.000192481,0.00028480397],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006265748,0.00066177204,0.00055267644,0.00038000476,0.0002126714,0.00011962607,0.00060835155,0.0005666114,0.00007273284],"category_scores_gemma":[0.00021950618,0.0008179515,0.0002505711,0.00061989424,0.00007957564,0.000006230677,0.000862597,0.00086564757,0.000009241847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005555242,0.00035926938,0.009965186,0.00017092758,0.00012530411,0.00008258857,0.00001777541,0.049967237,0.9391513,0.000014697269,0.00008947959,7.2242324e-7],"study_design_scores_gemma":[0.001924752,0.00015121719,0.057442,0.00025137296,0.00018564482,2.2718999e-7,0.000028087568,0.012643048,0.9180286,5.131085e-7,0.0076421415,0.0017024305],"about_ca_topic_score_codex":0.00012620907,"about_ca_topic_score_gemma":0.00008989936,"teacher_disagreement_score":0.047476813,"about_ca_system_score_codex":0.00027808838,"about_ca_system_score_gemma":0.0004528651,"threshold_uncertainty_score":0.99942714},"labels":[],"label_agreement":null},{"id":"W4297236282","doi":"10.1101/2022.09.25.509369","title":"Cryo-EM structure of the <i>Agrobacterium tumefaciens</i> type IV secretion system-associated T-pilus reveals stoichiometric protein-phospholipid assembly","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Agrobacterium tumefaciens; Pilus; Pilin; Protein filament; Biology; Biophysics; Cell biology; Biochemistry; Escherichia coli; Transformation (genetics); Gene","score_opus":0.005873865421910286,"score_gpt":0.22161108559354384,"score_spread":0.21573722017163355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297236282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925775,0.0018040113,0.00066668954,0.00002554338,0.0024706596,0.0012168831,0.0011196214,0.00011041212,0.000008665454],"genre_scores_gemma":[0.9986397,0.00007246696,0.0006136736,0.000059886548,0.00033335536,0.00008985098,0.000011099715,0.00014210795,0.00003783909],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99696904,0.0002773133,0.0006705244,0.00095533795,0.0005715299,0.00055624096],"domain_scores_gemma":[0.996832,0.000018052833,0.00072382885,0.0016570078,0.0006037778,0.00016530427],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053071533,0.0005844041,0.00061514653,0.00023787154,0.00021784764,0.000100341524,0.0009619089,0.00068291975,0.000036061127],"category_scores_gemma":[0.00045593167,0.0005484514,0.00027719644,0.0013423226,0.00007197698,0.00000772208,0.0011828399,0.00075468945,0.0000032262433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000398564,0.00005851956,0.0017792739,0.00067526754,0.00016795227,0.000004750496,0.000010967416,0.001261402,0.9957102,0.00004616503,0.00024468722,9.5196776e-7],"study_design_scores_gemma":[0.00050230866,0.000206949,0.07063687,0.00033426247,0.00017220159,1.3973207e-7,0.000015802394,0.00026390282,0.92460406,8.0308547e-7,0.0025124042,0.0007503059],"about_ca_topic_score_codex":0.000041595707,"about_ca_topic_score_gemma":0.000005774273,"teacher_disagreement_score":0.07110616,"about_ca_system_score_codex":0.00028732314,"about_ca_system_score_gemma":0.00045606267,"threshold_uncertainty_score":0.9996967},"labels":[],"label_agreement":null},{"id":"W4297749556","doi":"","title":"Les biotechnologies au secours des espèces menacées","year":2010,"lang":"fr","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Espace pour la vie","funders":"","keywords":"Geography","score_opus":0.011709318402266569,"score_gpt":0.262335506905543,"score_spread":0.25062618850327645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297749556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.770468,0.01019489,0.18800278,0.006733735,0.0005206402,0.0003199727,0.00009462515,0.00016845136,0.023496918],"genre_scores_gemma":[0.90991515,0.005738374,0.073441245,0.00002619514,0.00008648805,0.00005759765,0.0004195429,0.000064917,0.010250506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966039,0.0011747301,0.00047908965,0.0009207581,0.00023602447,0.0005854908],"domain_scores_gemma":[0.99604625,0.0003028775,0.00029605656,0.0020737562,0.0010912438,0.00018982029],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0024372593,0.00049721746,0.00037395197,0.00013627035,0.0005086484,0.00024516543,0.0013803064,0.0011773926,0.00013015368],"category_scores_gemma":[0.0014677801,0.000540733,0.0002864315,0.00021146762,0.0010128632,0.0000114442455,0.0016630669,0.000912703,0.00002877126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017273394,0.00044556384,0.0063777682,0.000431451,0.00026446453,0.00000552115,0.0042742663,0.00083561265,0.5952142,0.031479355,0.0005798661,0.36007464],"study_design_scores_gemma":[0.00029244056,0.0000014811258,0.0081656845,0.00073951844,0.000064590575,0.00002385227,0.00039806738,0.0014579052,0.8716465,0.0018456267,0.11479401,0.00057028333],"about_ca_topic_score_codex":0.0029668882,"about_ca_topic_score_gemma":0.013810897,"teacher_disagreement_score":0.35950437,"about_ca_system_score_codex":0.00009575534,"about_ca_system_score_gemma":0.00029043676,"threshold_uncertainty_score":0.9997044},"labels":[],"label_agreement":null},{"id":"W4297905850","doi":"10.3389/fpls.2022.934002","title":"Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9-generated diallelic mutants reveal Arabidopsis actin-related protein 2 function in the trafficking of syntaxin PEN1","year":2022,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Saskatchewan Research Council (Canada); Global Institute for Water Security; University of Saskatchewan; Agriculture and Agri-Food Canada","funders":"Ohio State University","keywords":"Biology; Arabidopsis; Cell biology; Mutant; Genetics; Gene","score_opus":0.008647370726606422,"score_gpt":0.24225059815312763,"score_spread":0.2336032274265212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297905850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995603,0.00025962328,0.0024405292,0.00012931293,0.0004835676,0.0009381028,0.00004973265,0.000017000317,0.00007908401],"genre_scores_gemma":[0.99885213,0.000010341345,0.00059018313,0.000031708427,0.00002281957,0.0001663166,0.000113435875,0.000017967728,0.00019510323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777555,0.000279297,0.00046144568,0.0005735997,0.00046912523,0.0004409808],"domain_scores_gemma":[0.9993313,0.000011842403,0.00015710661,0.00039751545,0.000048548,0.00005368925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018887393,0.00019569606,0.0002591622,0.00030140032,0.00019803845,0.000039951214,0.0006496348,0.00011393787,0.000006829146],"category_scores_gemma":[0.00025552476,0.00018046233,0.000071582646,0.0010540842,0.00015912068,0.000017582877,0.00017991713,0.00035701884,3.4720347e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002712184,0.00011182676,0.003120709,0.000016733347,0.00002875046,0.000025427124,0.00089945266,0.0076981485,0.98615694,0.000007817613,0.00043063483,0.0012323539],"study_design_scores_gemma":[0.0026602047,0.0014834652,0.041825294,0.00034142818,0.000059968494,0.00012954362,0.008236544,0.03998845,0.90362537,0.00013966716,0.00054673915,0.00096332084],"about_ca_topic_score_codex":0.0000898526,"about_ca_topic_score_gemma":0.00015148982,"teacher_disagreement_score":0.08253156,"about_ca_system_score_codex":0.00016398185,"about_ca_system_score_gemma":0.00018094013,"threshold_uncertainty_score":0.73590404},"labels":[],"label_agreement":null},{"id":"W4297985165","doi":"10.1016/j.xpro.2022.101734","title":"Protocol to use RNaseH1-based CRISPR to modulate locus-associated R-loops","year":2022,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs","keywords":"Locus (genetics); Biology; Nucleic acid; CRISPR; Computational biology; Chromatin; Genetics; Chromosome conformation capture; DNA; RNA; In silico; Gene; Cell biology; Gene expression; Enhancer","score_opus":0.023174409419151207,"score_gpt":0.36081946044868773,"score_spread":0.3376450510295365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297985165","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10253436,0.0000021956362,0.018315645,0.0003615141,0.00007277629,0.87820035,0.00023220509,0.000099991055,0.00018097128],"genre_scores_gemma":[0.13563175,3.7669913e-8,0.002918595,0.0011241505,0.000069734124,0.85915804,0.00006856306,0.00006253644,0.00096658437],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981306,0.00012611742,0.0003462858,0.0005520842,0.00034358865,0.0005013052],"domain_scores_gemma":[0.99886614,0.000013047795,0.00007516359,0.00066391396,0.000115258685,0.0002664884],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038427394,0.00025800726,0.00020988577,0.00010748645,0.00021763882,0.00007077835,0.00039102032,0.00008398609,0.00019391291],"category_scores_gemma":[0.00019472041,0.00027688948,0.00011406775,0.00034223913,0.000015919588,0.000004442844,0.00039870164,0.00017692786,0.000030240048],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008426356,0.00038657244,0.0017831003,0.00008526972,0.00006288615,0.000023483142,0.00014463758,0.08222263,0.89066744,0.000021696273,0.021559712,0.0021999609],"study_design_scores_gemma":[0.0016444279,0.0018810547,0.0024621321,0.000035940626,0.000007065609,0.0000029202818,0.000029474932,0.00056102977,0.40233275,0.000020774678,0.5905863,0.00043612273],"about_ca_topic_score_codex":0.0000678865,"about_ca_topic_score_gemma":0.00005759993,"teacher_disagreement_score":0.5690266,"about_ca_system_score_codex":0.00008851056,"about_ca_system_score_gemma":0.00014915042,"threshold_uncertainty_score":0.99996835},"labels":[],"label_agreement":null},{"id":"W4298009674","doi":"10.1016/j.addr.2022.114562","title":"Reversibility and therapeutic development for neurodevelopmental disorders, insights from genetic animal models","year":2022,"lang":"en","type":"review","venue":"Advanced Drug Delivery Reviews","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Neuroscience; Translational research; Animal model; Cognitive science; Biology; Psychology; Biotechnology","score_opus":0.03279438436945651,"score_gpt":0.31449829546726665,"score_spread":0.2817039110978101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298009674","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018767453,0.99167275,0.0033594437,0.0000031633251,0.00023718993,0.0027157231,0.00007828063,0.000019514642,0.0000371752],"genre_scores_gemma":[0.00016025965,0.9829488,0.014534148,0.00009144631,0.00008335963,0.0010804019,0.0008952064,0.0000881877,0.000118232536],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974061,0.00017698981,0.0008446028,0.0010737937,0.00014628058,0.0003522244],"domain_scores_gemma":[0.9989295,0.00008264664,0.00027589445,0.00056035793,0.000024022218,0.00012760705],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017452885,0.00060392474,0.0011995911,0.00006584078,0.00020419512,0.000023005345,0.00035973266,0.00014537908,0.000027709444],"category_scores_gemma":[0.00003229629,0.00054659246,0.00038030863,0.000122015066,0.000044247576,0.000008162086,0.00038566501,0.00020392718,0.000005880518],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021436323,0.000036267462,0.000002402781,0.0038533737,0.00009736044,0.0000010274747,0.00007397433,0.00009786745,0.00016235012,0.0000028039963,0.00010131211,0.9955498],"study_design_scores_gemma":[0.00028607808,0.00007464735,0.0000117232685,0.0013165595,0.000246642,0.0000049951577,0.000018588675,0.00007465641,0.000075241136,0.00006492757,0.9971894,0.000636524],"about_ca_topic_score_codex":0.000004819679,"about_ca_topic_score_gemma":0.000059620754,"teacher_disagreement_score":0.99708813,"about_ca_system_score_codex":0.00007718399,"about_ca_system_score_gemma":0.00023528961,"threshold_uncertainty_score":0.9996986},"labels":[],"label_agreement":null},{"id":"W4298059680","doi":"","title":"A new powerful tool to decipher retroviral vector silencing mechanisms in pluripotent cells","year":2011,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"DECIPHER; Induced pluripotent stem cell; Gene silencing; Computational biology; Biology; Vector (molecular biology); Computer science; Cell biology; Genetics; Embryonic stem cell; Gene","score_opus":0.0077091815521143385,"score_gpt":0.23278071927081972,"score_spread":0.2250715377187054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298059680","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35004294,0.0007603246,0.64204264,0.0005997979,0.00040683622,0.000451034,0.000024861298,0.000048282833,0.0056232805],"genre_scores_gemma":[0.85866797,0.00020722664,0.13374382,0.00011568063,0.000056176224,0.00003623715,0.00014906426,0.00006035572,0.0069634686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758273,0.00060248136,0.00041665172,0.000786219,0.0002277414,0.0003841834],"domain_scores_gemma":[0.9976592,0.00006112584,0.0001473569,0.0015337006,0.00038944586,0.00020914018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014409475,0.00032158766,0.0002810965,0.00013192884,0.000059961196,0.00010987773,0.00080794893,0.00034636585,0.00013648208],"category_scores_gemma":[0.0004112301,0.0003672077,0.00017417315,0.00016979073,0.000028811282,0.0000052879186,0.0012881176,0.00035926423,0.000042176212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036950274,0.00014757746,0.00018402677,0.00007735277,0.000053508924,0.000006629021,0.0032230513,0.0011604665,0.9747997,0.002709689,0.0019613714,0.015639681],"study_design_scores_gemma":[0.00037888857,0.0000023623747,0.0016460081,0.0005184273,0.000020467165,0.000004227203,0.00005874651,0.0008524979,0.9900339,0.0009023987,0.0051148566,0.00046722006],"about_ca_topic_score_codex":0.0012185919,"about_ca_topic_score_gemma":0.0017322635,"teacher_disagreement_score":0.50862503,"about_ca_system_score_codex":0.00007408908,"about_ca_system_score_gemma":0.00025551242,"threshold_uncertainty_score":0.999878},"labels":[],"label_agreement":null},{"id":"W4298093917","doi":"","title":"The D4Z4 insulator protects retrovirus transgenes from silencing in pluripotent stem cells","year":2011,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Structural Genomics Consortium; Canada Research Chairs; University of Toronto","funders":"","keywords":"Gene silencing; Induced pluripotent stem cell; Retrovirus; Transgene; Cell biology; Biology; Virology; Embryonic stem cell; Genetics; Gene; Virus","score_opus":0.011331015273592262,"score_gpt":0.22654177687892252,"score_spread":0.21521076160533026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298093917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93492925,0.0070744352,0.054779485,0.00038960302,0.00031808153,0.00059820263,0.00005945571,0.000045849723,0.001805644],"genre_scores_gemma":[0.9917447,0.0019326076,0.004620826,0.000026558037,0.000048234124,0.000117495016,0.00011828994,0.000047377645,0.001343918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99715406,0.0012302175,0.00042427288,0.0006610139,0.00021025691,0.00032017808],"domain_scores_gemma":[0.99752086,0.00016443004,0.00020059592,0.0016193342,0.0003866924,0.00010810419],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017095186,0.00028952557,0.00023674044,0.00006369979,0.0001749688,0.0001337584,0.0009025575,0.00033775275,0.000014736164],"category_scores_gemma":[0.0001486492,0.00026493904,0.00016550542,0.00011480306,0.000103815684,0.000004424102,0.000674229,0.00043536982,0.000008398874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039665545,0.00016152418,0.0007867037,0.000109248525,0.00009741762,0.000004210921,0.004263397,0.0010852909,0.958319,0.0005299521,0.00011963146,0.03448393],"study_design_scores_gemma":[0.0003113077,8.802894e-7,0.002678169,0.00045035276,0.000018018794,0.0000014754664,0.00011655785,0.0019300022,0.98955554,0.00031675617,0.004319891,0.00030107252],"about_ca_topic_score_codex":0.001582445,"about_ca_topic_score_gemma":0.0029625767,"teacher_disagreement_score":0.05681545,"about_ca_system_score_codex":0.000046602912,"about_ca_system_score_gemma":0.00017196893,"threshold_uncertainty_score":0.9999803},"labels":[],"label_agreement":null},{"id":"W4298139687","doi":"10.3389/fvets.2022.991844","title":"High-throughput plant breeding approaches: Moving along with plant-based food demands for pet food industries","year":2022,"lang":"en","type":"article","venue":"Frontiers in Veterinary Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"University of Guelph","keywords":"Throughput; Pet food; Front (military); Volume (thermodynamics); Food processing; Biotechnology; Agricultural economics; Biology; Food science; Computer science; Engineering; Economics; Mechanical engineering","score_opus":0.029558566034340254,"score_gpt":0.2471442786156664,"score_spread":0.21758571258132614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298139687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86587906,0.00035593193,0.13261646,0.000052403695,0.00054502545,0.0002721316,0.00022066256,0.000017670669,0.000040666822],"genre_scores_gemma":[0.9618419,0.0000068603536,0.037678804,0.000057654765,0.0000787339,0.00014550544,0.00014563765,0.000020470328,0.000024426316],"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854124,0.000024874702,0.00018421952,0.000538187,0.00026217874,0.0004493266],"domain_scores_gemma":[0.99955034,0.000015403231,0.00006424994,0.00026986166,0.00002135876,0.000078765246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045569637,0.00017712996,0.00017137926,0.00021501884,0.00036519585,0.000047561167,0.0004705063,0.00004331728,0.0000022780303],"category_scores_gemma":[0.000041099524,0.00017729704,0.000036575097,0.0004451193,0.00020566728,0.000017461085,0.00024748265,0.00015259124,7.770059e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033617925,0.00053050346,0.0629783,0.0005157427,0.00026053665,0.00023514735,0.0020334797,0.50889915,0.4021964,0.0009507029,0.0070760758,0.010962165],"study_design_scores_gemma":[0.014222822,0.11795465,0.02605151,0.00040046053,0.00015619473,0.0029571368,0.02742335,0.27330267,0.44146886,0.00037177853,0.09095915,0.0047314335],"about_ca_topic_score_codex":0.000009389838,"about_ca_topic_score_gemma":0.000009321332,"teacher_disagreement_score":0.23559648,"about_ca_system_score_codex":0.00007086442,"about_ca_system_score_gemma":0.0002641438,"threshold_uncertainty_score":0.72299635},"labels":[],"label_agreement":null},{"id":"W4298141287","doi":"10.3389/fbioe.2022.1019081","title":"New genomic techniques and their European Union reform. Potential policy changes and their implications","year":2022,"lang":"en","type":"article","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Ministerstwo Edukacji i Nauki","keywords":"European union; Political science; Economics; International trade","score_opus":0.0038421930846050108,"score_gpt":0.21702918321768777,"score_spread":0.21318699013308276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298141287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71559465,0.019796459,0.25682682,0.0068701836,0.0002376805,0.00027676712,0.00006987594,0.00018436903,0.00014320719],"genre_scores_gemma":[0.9866261,0.0059989407,0.007011814,0.000049137547,0.00013913769,0.00001916626,0.000035879253,0.000028047063,0.000091789494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993317,0.00002760432,0.00010982114,0.0002939276,0.00001874244,0.00021817388],"domain_scores_gemma":[0.99970275,0.0000019449026,0.000026233327,0.00020779412,0.000005951057,0.000055340177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015402133,0.00016113829,0.00013674423,0.00029487032,0.00009684898,0.0000144057285,0.0001357393,0.00012502293,7.6965335e-7],"category_scores_gemma":[0.0000061947335,0.00014596086,0.000018864599,0.00015261189,0.000071789305,0.000002686072,0.00039847937,0.0001748343,6.33352e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007916878,0.000007146129,0.0003368451,0.000015014426,0.00002374861,0.0000015370716,0.000081115315,0.00009708112,0.7063708,0.00018687567,0.00027245827,0.29259953],"study_design_scores_gemma":[0.001039497,0.0010356822,0.009202383,0.000029354449,0.000018331166,0.001025331,0.002204031,0.002880853,0.59241974,0.0008341298,0.38846236,0.0008482789],"about_ca_topic_score_codex":0.000069157504,"about_ca_topic_score_gemma":0.00001307751,"teacher_disagreement_score":0.3881899,"about_ca_system_score_codex":0.000031275,"about_ca_system_score_gemma":0.000015532098,"threshold_uncertainty_score":0.5952111},"labels":[],"label_agreement":null},{"id":"W4299287602","doi":"10.1016/j.omtn.2022.09.022","title":"Prime editing optimized RTT permits the correction of the c.8713C&gt;T mutation in DMD gene","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Dystrophin; Duchenne muscular dystrophy; Biology; Genetics; Gene; Molecular biology; Point mutation; Genome editing; CRISPR; Mutation","score_opus":0.005030096959285638,"score_gpt":0.2462696659657221,"score_spread":0.24123956900643648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4299287602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98478955,0.0016980788,0.011781942,0.00026508968,0.00072124205,0.00036624217,0.0000071286195,0.000013365607,0.00035735144],"genre_scores_gemma":[0.9986284,0.000094809155,0.00045776454,0.00033054888,0.00010274061,0.00007593638,0.00003527949,0.000036261346,0.00023828642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889135,0.00019034323,0.000234723,0.00024744403,0.000238858,0.0001972488],"domain_scores_gemma":[0.9993953,0.000013053117,0.00010394095,0.00042020544,0.000043028063,0.000024438119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003281603,0.00014376479,0.00012859522,0.000043334916,0.0001714478,0.000014570231,0.00033175436,0.00006670733,0.00005085268],"category_scores_gemma":[0.000045915935,0.00010957416,0.00014185162,0.00024162576,0.000055605007,0.0000030660801,0.00016059606,0.00018630565,0.0000011085679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007543296,0.00004396626,0.00032310898,0.0000031077548,0.00003767652,0.0000038073006,0.00033668682,0.06720002,0.92102754,0.000010323112,0.00011803,0.010820307],"study_design_scores_gemma":[0.0011003587,0.00020408962,0.0038424549,0.000007247411,0.000013589729,0.000041907064,0.00033984773,0.006758978,0.9792997,0.000025691035,0.008214335,0.0001517541],"about_ca_topic_score_codex":0.000027219123,"about_ca_topic_score_gemma":0.000005872995,"teacher_disagreement_score":0.060441043,"about_ca_system_score_codex":0.000034374352,"about_ca_system_score_gemma":0.000045524328,"threshold_uncertainty_score":0.44683045},"labels":[],"label_agreement":null},{"id":"W4300117908","doi":"10.17615/zear-h193","title":"High Nucleosome Occupancy Is Encoded at Human Regulatory Sequences","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Ontario Genomics Institute; Canadian Institute for Advanced Research; Howard Hughes Medical Institute","keywords":"Nucleosome; Occupancy; Computational biology; Genetics; Biology; Histone; Computer science; DNA","score_opus":0.013332001604015702,"score_gpt":0.2554093160489223,"score_spread":0.2420773144449066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300117908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99423033,0.0019419031,0.00087569543,0.0011995413,0.00014191889,0.00008978051,0.00003342874,0.00007028739,0.0014171306],"genre_scores_gemma":[0.9924525,0.000021726475,0.003962793,0.0016598031,0.00045650327,0.0000068190316,0.00009693152,0.000026112164,0.0013168271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992127,0.000014787844,0.00015726367,0.00030902945,0.00011034454,0.0001959025],"domain_scores_gemma":[0.99956906,0.0000057085754,0.000036999903,0.0002527148,0.000017659057,0.00011784337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002543836,0.00014984152,0.0001348032,0.0000178963,0.00011653987,0.000046799447,0.00020318021,0.000110178364,0.00026640054],"category_scores_gemma":[0.000022223718,0.00014445151,0.00006960936,0.00007271121,0.00010365816,0.00000994902,0.00019399263,0.000059680042,0.000034626315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003526319,0.000010792466,0.004427286,0.000044559223,0.000049754744,0.0000061460037,0.00054669526,0.000100657635,0.9520848,0.012496935,0.029976318,0.00022082869],"study_design_scores_gemma":[0.00025379017,0.00014493434,0.0027605619,0.000007655716,0.000011944933,0.000003131179,0.0000755183,0.00002951091,0.9469292,0.0022875615,0.04727831,0.00021787082],"about_ca_topic_score_codex":0.000008698742,"about_ca_topic_score_gemma":0.0000044846593,"teacher_disagreement_score":0.017301995,"about_ca_system_score_codex":0.000005419811,"about_ca_system_score_gemma":0.000036784244,"threshold_uncertainty_score":0.58905613},"labels":[],"label_agreement":null},{"id":"W4301254839","doi":"10.3791/61124-v","title":"High-Resolution Mapping of Protein-DNA Interactions in Mouse Stem Cell-Derived Neurons using Chromatin Immunoprecipitation-Exonuclease (ChIP-Exo)","year":2020,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chromatin immunoprecipitation; Exonuclease; Exonuclease III; ChIP-sequencing; Immunoprecipitation; Biology; ChIP-on-chip; DNA; Chromatin; Molecular biology; Genomic library; DNA sequencing; Computational biology; Cell biology; Genetics; Gene; Gene expression; DNA polymerase; Chromatin remodeling; Escherichia coli; Promoter","score_opus":0.030627185267893733,"score_gpt":0.3729726182878657,"score_spread":0.342345433019972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4301254839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97739035,0.00059935456,0.02159478,0.000042749656,0.0001498827,0.00019293623,0.0000072729745,0.0000053901276,0.000017260183],"genre_scores_gemma":[0.9899743,0.000041852774,0.009763306,0.000044927398,0.00010771816,0.000006447088,0.000009340813,0.000025670895,0.00002643009],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988392,0.00009252531,0.0006048704,0.00014673042,0.00016488052,0.00015180759],"domain_scores_gemma":[0.99929875,0.000009537881,0.0003819179,0.000121439785,0.00009557224,0.000092778646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010275976,0.00013870336,0.00023692983,0.0001070886,0.000040558083,0.000018531904,0.00014046016,0.000050762057,0.000020425063],"category_scores_gemma":[0.0000390475,0.00014457638,0.00011284712,0.00012143603,0.00002364778,0.000018398885,0.000067130386,0.00012180981,0.0000013837291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021563884,0.00015406447,0.00007971738,0.000041394873,0.00005025155,0.0000049142327,0.0013465604,0.0054928605,0.99239504,0.0000035219095,0.00003650594,0.0001795304],"study_design_scores_gemma":[0.0017181238,0.00028093127,0.0005035089,0.000086029555,0.000013667635,0.000009592999,0.001285758,0.0035563917,0.9922131,0.000002001903,0.00020796864,0.00012294078],"about_ca_topic_score_codex":0.000028774884,"about_ca_topic_score_gemma":0.0000015750787,"teacher_disagreement_score":0.012583933,"about_ca_system_score_codex":0.00003912411,"about_ca_system_score_gemma":0.000057781286,"threshold_uncertainty_score":0.58956534},"labels":[],"label_agreement":null},{"id":"W4303199315","doi":"10.1038/s41467-022-33669-z","title":"Marker-free co-selection for successive rounds of prime editing in human cells","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Selection (genetic algorithm); Prime (order theory); Computer science; Computational biology; Genome editing; Biology; Genetics; Artificial intelligence; CRISPR; Gene; Combinatorics; Mathematics","score_opus":0.009122689201274632,"score_gpt":0.3412505014385889,"score_spread":0.3321278122373143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303199315","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93912834,0.0151364505,0.033402927,0.0016073734,0.0006963241,0.001501078,0.00053626735,0.000055697637,0.007935565],"genre_scores_gemma":[0.994548,0.00004933984,0.004574026,0.000044268723,0.000065843014,0.00012815848,0.00041339666,0.000012528291,0.00016443952],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995125,0.000054275817,0.00015077084,0.00011489257,0.00006818124,0.000099394165],"domain_scores_gemma":[0.99914986,0.000046105983,0.00007116429,0.0006548295,0.00006190009,0.000016148771],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002035382,0.00006037689,0.00007489604,0.00005955519,0.00019069541,0.000006312498,0.00059616484,0.00009242375,0.000009790858],"category_scores_gemma":[0.00007874762,0.00007346672,0.00004833865,0.00012692153,0.000028887574,0.0000021795881,0.00030749151,0.00028970948,9.476382e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001471617,0.000083273255,0.0032086396,0.000013240127,0.000019869787,5.383476e-8,0.000070101334,0.0011458346,0.990268,0.00081395125,0.0038575288,0.00050479494],"study_design_scores_gemma":[0.0009517132,0.00024512073,0.0052103424,0.000012857247,0.000023467106,0.000004494043,0.00043380397,0.0040866183,0.846029,0.00020232362,0.14259315,0.00020713986],"about_ca_topic_score_codex":0.000023009634,"about_ca_topic_score_gemma":0.0003713338,"teacher_disagreement_score":0.14423902,"about_ca_system_score_codex":0.000026770202,"about_ca_system_score_gemma":0.000030481922,"threshold_uncertainty_score":0.2995886},"labels":[],"label_agreement":null},{"id":"W4303411333","doi":"10.2144/btn-2022-0102","title":"Biohacking the Food Chain: Using CRISPR to Combat the Global Food Crisis","year":2022,"lang":"en","type":"article","venue":"BioTechniques","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"CRISPR; Food waste; Global population; Population; Climate change; Key (lock); Business; Food chain; Biotechnology; Natural resource economics; Biology; Ecology; Environmental health; Economics; Gene; Genetics; Medicine","score_opus":0.018523422157232766,"score_gpt":0.31605768908538184,"score_spread":0.2975342669281491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303411333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7437295,0.0041493615,0.24560665,0.0045842635,0.00042016353,0.0008254021,0.00016613476,0.000152487,0.00036607333],"genre_scores_gemma":[0.99523276,0.00005345068,0.0025504837,0.001822456,0.00020030909,0.00009011123,0.000012996352,0.000022680237,0.000014763746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990252,0.00008327325,0.00015932009,0.0002827062,0.00018012489,0.00026932752],"domain_scores_gemma":[0.99932706,0.000009230262,0.000042609743,0.00053510413,0.00003418904,0.000051820232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031568873,0.00015777498,0.00010202402,0.000027960255,0.00042551343,0.000048315,0.00050064095,0.00008096901,0.00001421582],"category_scores_gemma":[0.000028600349,0.000110777684,0.00010793249,0.00024343947,0.000038022976,0.000001775779,0.000644257,0.00015024153,9.88383e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011708376,0.00014164226,0.0011965721,0.00004219828,0.0003058909,0.0000055936607,0.00073770655,0.0064785397,0.93296736,0.0051656216,0.0413982,0.011443558],"study_design_scores_gemma":[0.00011684962,0.0009493668,0.00036977412,0.000007573491,0.000028408647,0.000057898007,0.00081150525,0.00031988617,0.7833568,0.0005223218,0.21318763,0.00027198656],"about_ca_topic_score_codex":0.0000767684,"about_ca_topic_score_gemma":0.000043906213,"teacher_disagreement_score":0.2515033,"about_ca_system_score_codex":0.000057934638,"about_ca_system_score_gemma":0.000034794535,"threshold_uncertainty_score":0.45173827},"labels":[],"label_agreement":null},{"id":"W4303446666","doi":"10.1038/s41596-022-00741-3","title":"Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression","year":2022,"lang":"en","type":"review","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"DNA demethylation; Biology; DNA methylation; CRISPR; Epigenetics; DNA; Genetics; Transcription (linguistics); Methylation; Gene; Molecular biology; Gene expression","score_opus":0.04234329875881832,"score_gpt":0.43447926800779496,"score_spread":0.39213596924897665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303446666","genre_codex":"review","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005378809,0.6980621,0.19595969,0.0000418854,0.0009394182,0.10391759,0.0003906338,0.00009134605,0.000059432426],"genre_scores_gemma":[0.0036353099,0.17578778,0.2211359,0.0018409534,0.0072947047,0.5784634,0.009625248,0.0014424477,0.00077426137],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99643195,0.0004482272,0.0008221628,0.0011628589,0.00059959694,0.0005352245],"domain_scores_gemma":[0.99781525,0.00006382368,0.00039365047,0.0013148013,0.00015644367,0.0002560494],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00068439293,0.0006952916,0.00094975386,0.00038540983,0.00020319512,0.00011665388,0.0008427438,0.0011336087,0.00013406746],"category_scores_gemma":[0.0005486757,0.00068590185,0.000400473,0.0006745697,0.000016519904,0.000012616103,0.0005898864,0.0008823593,0.000009511699],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020096781,0.00007800435,0.0000057037346,0.004411198,0.00011249587,0.000011905877,0.000048956517,0.0036707856,0.8051684,0.0000018395406,0.0028940197,0.18339574],"study_design_scores_gemma":[0.00044376322,0.00022793021,0.000031410524,0.001425276,0.000121868296,0.000011503136,0.0000035820965,0.00013266363,0.29175743,0.000007754626,0.7052215,0.00061534875],"about_ca_topic_score_codex":0.000008440593,"about_ca_topic_score_gemma":0.000010925318,"teacher_disagreement_score":0.70232743,"about_ca_system_score_codex":0.00021296296,"about_ca_system_score_gemma":0.00032165129,"threshold_uncertainty_score":0.9995592},"labels":[],"label_agreement":null},{"id":"W4303696810","doi":"10.5539/jas.v14n11p80","title":"Advances in Plant Breeding, Polemics of Genetically Modified Crops and Biosafety Frameworks in Ethiopia","year":2022,"lang":"en","type":"article","venue":"Journal of Agricultural Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biosafety; Agriculture; Agricultural biotechnology; Food security; Biotechnology; Population; Business; Genetically modified organism; Emerging technologies; Agricultural economics; Biology; Economics; Computer science; Ecology","score_opus":0.005536751186716267,"score_gpt":0.2670038535525459,"score_spread":0.26146710236582965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303696810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967168,0.0022284465,0.00048185157,0.00027267166,0.00012793428,0.000042403775,0.0000046859877,7.503081e-7,0.00012443888],"genre_scores_gemma":[0.9974769,0.0010836117,0.0013505974,0.00003432324,0.000044199835,0.0000010124286,0.0000012562086,0.0000018242131,0.000006276784],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99921155,0.000018142806,0.00026580997,0.00012119226,0.00022989692,0.00015338154],"domain_scores_gemma":[0.99970144,0.000013234845,0.00011289417,0.00005263242,0.00006231193,0.000057484678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004121485,0.00006445201,0.00011340136,0.00007437183,0.000044877357,0.000011596504,0.00023351752,0.000053413765,0.000002956499],"category_scores_gemma":[0.0000784581,0.000044432956,0.000028892355,0.00030332463,0.00010511427,0.000011540699,0.00014395051,0.00028204886,2.7374021e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032571636,0.000027037442,0.006265007,0.000008096236,0.0000019684574,0.0000038266885,0.00021000553,0.037736807,0.9537808,0.00020436644,0.000020102465,0.0017094492],"study_design_scores_gemma":[0.0006281291,0.0007510614,0.87211263,0.00006331357,0.0000062876506,0.00034519538,0.0012644877,0.0007655985,0.12299726,0.00015376216,0.00072707346,0.00018522116],"about_ca_topic_score_codex":0.000011787347,"about_ca_topic_score_gemma":0.000036311038,"teacher_disagreement_score":0.8658476,"about_ca_system_score_codex":0.000025482643,"about_ca_system_score_gemma":0.000049495262,"threshold_uncertainty_score":0.18119234},"labels":[],"label_agreement":null},{"id":"W4305081949","doi":"10.1016/j.omtm.2022.10.009","title":"LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Cancer Prevention and Research Institute of Texas; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; American Heart Association","keywords":"CRISPR; Transgene; Genetically modified mouse; Proof of concept; Chemistry; Cell biology; Biology; Computational biology; Molecular biology; Biochemistry; Computer science; Gene","score_opus":0.0395217700568771,"score_gpt":0.41685001948780315,"score_spread":0.377328249430926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4305081949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56291413,0.00035996237,0.43586344,0.000052407187,0.000091442234,0.00067847193,0.0000053051235,0.0000126549,0.000022175505],"genre_scores_gemma":[0.8119401,0.00007292796,0.18716708,0.00018158286,0.000020546222,0.00033161513,0.0000495363,0.00006310467,0.0001735197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966705,0.0008400421,0.0009202851,0.0007581827,0.00041519178,0.0003958358],"domain_scores_gemma":[0.99905163,0.00005281481,0.00015928062,0.0005349556,0.00006870937,0.00013263735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020798398,0.00032725546,0.00047803504,0.000115655355,0.00009753663,0.000015489506,0.0004047825,0.00013107841,0.000025635047],"category_scores_gemma":[0.000053432705,0.00030243644,0.00019976226,0.00027483155,0.00007877129,0.0000047855356,0.0001672531,0.0003729864,4.9062595e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019379911,0.0026779259,0.003911457,0.000028729586,0.0006672948,0.000029250277,0.0026338391,0.28232557,0.41214696,0.000015887083,0.000023307317,0.29360178],"study_design_scores_gemma":[0.004817373,0.0026716122,0.0018110684,0.000013821625,0.00004196665,0.000006304139,0.0007331406,0.0052019595,0.98031706,0.000056527,0.0037448278,0.0005843585],"about_ca_topic_score_codex":0.000008877236,"about_ca_topic_score_gemma":0.000019773453,"teacher_disagreement_score":0.5681701,"about_ca_system_score_codex":0.000052711788,"about_ca_system_score_gemma":0.000268071,"threshold_uncertainty_score":0.9999428},"labels":[],"label_agreement":null},{"id":"W4306292889","doi":"10.1093/ve/veac100","title":"Formal recognition and classification of gene transfer agents as viriforms","year":2022,"lang":"en","type":"article","venue":"Virus Evolution","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Memorial University of Newfoundland","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Simons Foundation","keywords":"Gene transfer; Computer science; Artificial intelligence; Pattern recognition (psychology); Natural language processing; Gene; Biology; Genetics","score_opus":0.019570884706699165,"score_gpt":0.27240197532275157,"score_spread":0.2528310906160524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306292889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.948481,0.00042156607,0.050445385,0.00001894752,0.0000841728,0.000107467014,0.00006412665,0.000007231281,0.00037006207],"genre_scores_gemma":[0.999233,0.0000962989,0.00018037535,0.000026887825,0.00004268576,0.00003327278,0.00029675136,0.000008431709,0.0000822621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954504,0.00001835289,0.000118077514,0.00012982846,0.00008993443,0.00009879415],"domain_scores_gemma":[0.999834,0.0000015136123,0.000020655178,0.00009412546,0.00002361408,0.000026092623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011037713,0.000057036657,0.00005021017,0.000040607552,0.00008034191,0.0000033480997,0.000041275467,0.000040464216,0.000045594843],"category_scores_gemma":[0.000008419901,0.00006245731,0.000031154446,0.00005893331,0.000018124265,0.000004961567,0.000026729915,0.000044359014,0.0000047861727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067659814,0.000028655073,0.000303218,0.0000104641085,0.000011918487,1.904389e-7,0.0000630375,0.0004588524,0.9911305,0.00005077087,0.00013454618,0.0077402047],"study_design_scores_gemma":[0.0007457429,0.0005921348,0.07380119,0.0000046369787,0.000033336626,0.000038799833,0.00024841639,0.003023245,0.91273564,0.0003375106,0.008248961,0.00019038083],"about_ca_topic_score_codex":0.00003481756,"about_ca_topic_score_gemma":0.000012268068,"teacher_disagreement_score":0.07839484,"about_ca_system_score_codex":0.000019272366,"about_ca_system_score_gemma":0.000018071032,"threshold_uncertainty_score":0.2546935},"labels":[],"label_agreement":null},{"id":"W4306353454","doi":"10.1101/2022.10.15.512367","title":"SLICER: Seamless Loss of Integrated Cassettes Using Endonuclease Cleavage and Recombination in <i>Deinococcus radiodurans</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deinococcus radiodurans; Selectable marker; Genome; Endonuclease; Genome editing; Restriction enzyme; Computational biology; Biology; Transformation (genetics); Gene; DNA; Genetics; Homing endonuclease","score_opus":0.00879611802290653,"score_gpt":0.24705960825018705,"score_spread":0.23826349022728052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306353454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938779,0.0029739563,0.001874074,0.000040835454,0.0004386119,0.00046896894,0.00028027094,0.00003921341,0.000006186204],"genre_scores_gemma":[0.99710816,0.00087293255,0.0017054495,0.000049753224,0.00010029492,0.00006416205,0.0000054637258,0.000091377326,0.000002408328],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813414,0.00013681651,0.0004687296,0.0007382852,0.00018614448,0.00033589388],"domain_scores_gemma":[0.99881095,0.0000205604,0.00022440027,0.00067813403,0.0001426988,0.00012324487],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043479213,0.0003822933,0.00042213558,0.00023118951,0.00007208035,0.00005051464,0.00030457258,0.0003414392,0.000018968245],"category_scores_gemma":[0.00010838722,0.0004610269,0.0001000113,0.00030702533,0.00008700209,0.000008379755,0.00044228983,0.0004714104,5.6690885e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005460551,0.00009493784,0.022392252,0.0003490977,0.00007557459,0.000035422963,0.000013995781,0.0018081442,0.975082,0.000031654003,0.000051231837,0.000011079087],"study_design_scores_gemma":[0.00086776743,0.00009131079,0.042238496,0.00016230076,0.0000733804,1.7177032e-7,0.00002020036,0.0017292487,0.9513507,9.352235e-7,0.00289187,0.0005736546],"about_ca_topic_score_codex":0.00019950811,"about_ca_topic_score_gemma":0.000011368823,"teacher_disagreement_score":0.02373134,"about_ca_system_score_codex":0.00013452298,"about_ca_system_score_gemma":0.00026807058,"threshold_uncertainty_score":0.9997842},"labels":[],"label_agreement":null},{"id":"W4306765230","doi":"10.1177/01622439221122513","title":"Governing Agricultural Biotechnologies in the United States, the United Kingdom, and Germany: A Trans-decadal Study of Regulatory Cultures","year":2022,"lang":"en","type":"article","venue":"Science Technology & Human Values","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Economic and Social Research Council","keywords":"Agriculture; Biosafety; Jurisdiction; Political science; Politics; Novelty; Corporate governance; German; Agricultural biotechnology; Science policy; Biotechnology; Biology; Public administration; Law; Management; Geography; Economics; Ecology","score_opus":0.015247362891048666,"score_gpt":0.31178644522474946,"score_spread":0.2965390823337008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306765230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983047,0.0005068195,0.00003723802,0.0007083862,0.000038317277,0.00030847223,0.000006640627,0.0000610752,0.000028300625],"genre_scores_gemma":[0.99973625,0.00004040648,0.000052961084,0.000054573342,0.000011244161,0.00005467818,0.000016658521,0.000006675198,0.000026559881],"study_design_codex":"bench_or_experimental","study_design_gemma":"qualitative","domain_scores_codex":[0.9988321,0.00007941667,0.00019964988,0.0003328542,0.00028845418,0.00026754057],"domain_scores_gemma":[0.9993949,0.000017694738,0.00008224386,0.00043820235,0.000051666208,0.000015287284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007049871,0.00013736686,0.00012321827,0.0004639054,0.0008744959,0.000028767592,0.0010191848,0.00008751851,0.0000027567598],"category_scores_gemma":[0.00006419406,0.00008184683,0.000026784284,0.0019963896,0.0015912598,0.0000061159026,0.00044801342,0.00034993605,1.2265538e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013191869,0.00015075108,0.005271338,0.000009447051,0.00002953831,0.0000061418777,0.005423271,0.009953567,0.975729,0.0027481667,0.00020709618,0.0004585271],"study_design_scores_gemma":[0.0019548328,0.0035964577,0.24374367,0.000036999343,0.00009905165,0.00020247373,0.3892467,0.0012594116,0.3339498,0.0022117714,0.022956187,0.0007426283],"about_ca_topic_score_codex":0.00022289748,"about_ca_topic_score_gemma":0.00009006034,"teacher_disagreement_score":0.6417791,"about_ca_system_score_codex":0.00002432218,"about_ca_system_score_gemma":0.00002352902,"threshold_uncertainty_score":0.6726004},"labels":[],"label_agreement":null},{"id":"W4306873956","doi":"10.1038/s42003-022-03969-7","title":"Contribution of CRISPRable DNA to human complex traits","year":2022,"lang":"en","type":"review","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Global Health Research","funders":"Fudan University; National Natural Science Foundation of China","keywords":"CRISPR; Biology; Human genome; Gene; Computational biology; Genetics; Genome editing; Genome; Missing heritability problem; Heritability; Genomics; Functional genomics; Genetic variants; Genotype","score_opus":0.0921030250955317,"score_gpt":0.45576323048971895,"score_spread":0.36366020539418725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306873956","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00004064551,0.9949957,0.0026739864,0.00006492945,0.00007242232,0.0005236871,0.00026916052,0.000015969801,0.0013434911],"genre_scores_gemma":[0.005830046,0.9858784,0.0012272425,0.000049887734,0.000063262865,0.00030405686,0.0064973542,0.00003078604,0.00011893281],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986746,0.00030432438,0.0004891465,0.00027982454,0.000044419772,0.0002077003],"domain_scores_gemma":[0.9981004,0.00007447548,0.00018203731,0.0015055594,0.0000757584,0.00006178586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024739382,0.0002087984,0.00065429317,0.00012965052,0.00018258282,0.0000061344726,0.0012656072,0.000236672,0.00013729393],"category_scores_gemma":[0.00015234297,0.0002122679,0.0002406436,0.00021909909,0.000116500065,9.368314e-7,0.0009766378,0.00020637081,0.000011051067],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008709446,0.00024742496,0.00001501478,0.0011411165,0.0004303479,4.060845e-7,0.000060123104,0.000020954836,0.046074547,0.008615436,0.008099395,0.9352865],"study_design_scores_gemma":[0.00010430103,0.00020322937,0.000013052013,0.00011254542,0.00011650868,0.000011071846,0.0000127527965,0.0000034629427,0.00032919337,0.00004099064,0.99885374,0.00019912035],"about_ca_topic_score_codex":0.000014555996,"about_ca_topic_score_gemma":0.000047356243,"teacher_disagreement_score":0.99075437,"about_ca_system_score_codex":0.00003598877,"about_ca_system_score_gemma":0.000095393305,"threshold_uncertainty_score":0.8656034},"labels":[],"label_agreement":null},{"id":"W4307211509","doi":"10.1172/jci.insight.162207","title":"GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion–positive rhabdomyosarcoma","year":2022,"lang":"en","type":"article","venue":"JCI Insight","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"University of California, San Francisco; National Institutes of Health; National Cancer Institute; Frank A. Campini Foundation; American Association for Cancer Research","keywords":"mTORC1; Fusion gene; Cancer research; FOXO1; Alveolar rhabdomyosarcoma; Biology; PAX3; Rhabdomyosarcoma; Gene; Computational biology; Genetics; Medicine; PI3K/AKT/mTOR pathway; Signal transduction; Transcription factor; Pathology","score_opus":0.010763180491516276,"score_gpt":0.29214058952175687,"score_spread":0.2813774090302406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307211509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99358916,0.001220014,0.0027324525,0.0003057331,0.0002480998,0.0002888134,0.000044824705,0.000018233442,0.0015526412],"genre_scores_gemma":[0.9986482,0.000057981808,0.00007126179,0.0005045305,0.000105771775,0.00011151538,0.000029582314,0.00002478765,0.0004463577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987129,0.0001547415,0.00017740445,0.0004500933,0.00022911024,0.00027577762],"domain_scores_gemma":[0.99939847,0.000023958288,0.00004585843,0.0004267174,0.000031967877,0.00007300871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022468649,0.00017771118,0.00016967132,0.000065922555,0.0001556151,0.000017531987,0.00020730382,0.00008830537,0.0002527743],"category_scores_gemma":[0.000020502326,0.00018223384,0.00010210293,0.0001558552,0.000036386915,0.000004219499,0.0003281803,0.00026946422,0.0000063752022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022586831,0.0004221454,0.0093377745,0.000020480833,0.000055682853,0.000024497083,0.0010300713,0.0010514808,0.97606933,0.00007531943,0.0004946164,0.011192722],"study_design_scores_gemma":[0.0012807965,0.0006452928,0.064091854,0.000008847925,0.000022213428,0.000039993625,0.00026947286,0.0006238078,0.8679641,0.00023669167,0.064321235,0.0004957166],"about_ca_topic_score_codex":0.00008650801,"about_ca_topic_score_gemma":0.00009377189,"teacher_disagreement_score":0.10810526,"about_ca_system_score_codex":0.000084684885,"about_ca_system_score_gemma":0.000072209936,"threshold_uncertainty_score":0.743128},"labels":[],"label_agreement":null},{"id":"W4307668581","doi":"10.1101/2022.10.26.513620","title":"License to cut: Smart RNA guides for conditional control of CRISPR-Cas9","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Agence Nationale de la Recherche","keywords":"Cas9; CRISPR; Synthetic biology; Computational biology; RNA; Guide RNA; Computer science; Genome editing; Flexibility (engineering); Genome engineering; Biology; Genetics; Gene; Mathematics","score_opus":0.01010864173983298,"score_gpt":0.2686151210075643,"score_spread":0.2585064792677313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307668581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7389878,0.0017563126,0.2511518,0.00037720386,0.0015020936,0.0017343088,0.004377674,0.000090968184,0.000021829224],"genre_scores_gemma":[0.9914536,0.00010526167,0.0064871795,0.0004612483,0.00061453326,0.00072186056,0.000011436649,0.000116217016,0.00002869188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978868,0.000060824488,0.000531621,0.0008159208,0.00026904733,0.00043580198],"domain_scores_gemma":[0.99805504,0.00004493139,0.00023258226,0.0009691956,0.0004676731,0.00023055305],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044747128,0.0004157525,0.00047255273,0.00016068468,0.0001158198,0.000044812128,0.0004935311,0.00033465977,0.00011004658],"category_scores_gemma":[0.00034211113,0.00045363762,0.00028042353,0.00014597912,0.00006299749,0.000003873121,0.00045162605,0.0002613808,0.0000061154706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001284558,0.00008459254,0.00094128615,0.0002833161,0.0002580865,0.0000055594787,0.0000054342513,0.003297662,0.9907396,0.00025889117,0.003995043,0.0000020930556],"study_design_scores_gemma":[0.0008133768,0.00021595514,0.008053724,0.000051536368,0.000121008256,2.7300203e-8,0.000005424446,0.00030926298,0.88103324,0.0000032437367,0.108837254,0.0005559728],"about_ca_topic_score_codex":0.000022860866,"about_ca_topic_score_gemma":0.0000044307953,"teacher_disagreement_score":0.25246575,"about_ca_system_score_codex":0.00006724318,"about_ca_system_score_gemma":0.00034546206,"threshold_uncertainty_score":0.99979156},"labels":[],"label_agreement":null},{"id":"W4307936084","doi":"10.1038/s41467-022-34320-7","title":"A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Roche (Canada)","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computer science; Guide RNA; Computational biology; Bioconductor; Genome engineering; Annotation; Biology; Gene; Genetics","score_opus":0.029717823233314195,"score_gpt":0.36284350568493456,"score_spread":0.3331256824516204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307936084","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3959169,0.43688688,0.14733006,0.012773336,0.00066141755,0.0038955268,0.0021459097,0.00020647755,0.000183463],"genre_scores_gemma":[0.9885724,0.001298722,0.009698673,0.00007241442,0.000014144293,0.00023834413,0.00004571009,0.000011749987,0.00004781399],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99954927,0.00005150488,0.00012868515,0.00011710847,0.00005293137,0.0001005129],"domain_scores_gemma":[0.99870867,0.00020382006,0.000057369896,0.0009155931,0.0001025182,0.000012034053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013931519,0.000072194896,0.00008455583,0.000019960742,0.00037272184,0.000011266663,0.0006582405,0.00008716424,0.0000016140324],"category_scores_gemma":[0.00015543964,0.000058799673,0.000044199,0.00008365509,0.00009808849,0.0000015203896,0.0007250202,0.00019144273,1.4480025e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052203908,0.000078733196,0.00025724442,0.000058372967,0.00018829442,1.938658e-7,0.00033424536,0.0038699824,0.9675292,0.0017674317,0.018593146,0.0072709722],"study_design_scores_gemma":[0.0002497237,0.00012562716,0.000380875,0.000005609758,0.000025345067,0.000017486893,0.004348517,0.001984632,0.14494036,0.000047717225,0.8477788,0.00009531182],"about_ca_topic_score_codex":0.000004923597,"about_ca_topic_score_gemma":0.000033262913,"teacher_disagreement_score":0.82918566,"about_ca_system_score_codex":0.000008387082,"about_ca_system_score_gemma":0.00002313541,"threshold_uncertainty_score":0.28667128},"labels":[],"label_agreement":null},{"id":"W4308055191","doi":"10.1111/febs.16673","title":"<scp>APOBEC3G</scp> protects the genome of human cultured cells and mice from radiation‐induced damage","year":2022,"lang":"en","type":"article","venue":"FEBS Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Israel Cancer Association; National Institute of Allergy and Infectious Diseases; Hebrew University of Jerusalem; University of Ottawa","keywords":"APOBEC3G; DNA damage; DNA repair; Biology; Downregulation and upregulation; Cell biology; In vitro; Innate immune system; Immunity; Genome instability; Cancer research; Carcinogenesis; Cytidine deaminase; DNA; Genetics; Cancer; Immune system; Gene","score_opus":0.007765937558666426,"score_gpt":0.25578710164188756,"score_spread":0.24802116408322114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308055191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99642843,0.002265828,0.00067831227,0.00006372243,0.00015038475,0.00013691586,0.000038664264,0.0000036335357,0.00023410031],"genre_scores_gemma":[0.9987023,0.00011557307,0.00031007812,0.000073050294,0.0003397848,0.000010782133,0.000028948185,0.000014012291,0.00040545486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993601,0.0000727852,0.00016156222,0.00013276836,0.0001348998,0.00013789392],"domain_scores_gemma":[0.99963284,0.00001352664,0.0001074731,0.0001527324,0.000034882738,0.000058540172],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002006156,0.0000897708,0.000092855415,0.000027514288,0.00028057283,0.000031791173,0.0001914784,0.00004373116,0.000028775614],"category_scores_gemma":[0.000033306453,0.000072192335,0.000056964618,0.000056524434,0.000021999404,0.000002621468,0.00012027497,0.00022006367,8.6360325e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004229596,0.000016591748,0.00009656844,0.0000054755487,0.000044277804,0.0000032644766,0.0005679822,0.0010562772,0.9968876,0.0000039292663,0.001101804,0.00021199638],"study_design_scores_gemma":[0.00057416764,0.00025969485,0.0134751545,0.000004323222,0.00003318008,0.000055871144,0.00075466343,0.00009227506,0.9508475,0.00008879306,0.033751834,0.000062562554],"about_ca_topic_score_codex":0.000019246623,"about_ca_topic_score_gemma":0.0000062439008,"teacher_disagreement_score":0.04604012,"about_ca_system_score_codex":0.000011900303,"about_ca_system_score_gemma":0.00003051272,"threshold_uncertainty_score":0.2943918},"labels":[],"label_agreement":null},{"id":"W4308178654","doi":"10.3390/agriculture12111780","title":"The Potential of Novel Gene Editing-Based Approaches in Forages and Rumen Archaea for Reducing Livestock Methane Emissions","year":2022,"lang":"en","type":"article","venue":"Agriculture","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"","keywords":"Methanogenesis; Greenhouse gas; Rumen; Archaea; Ruminant; Methane; Environmental science; Context (archaeology); Defaunation; Nitrous oxide; Climate change; Biotechnology; Agriculture; Methane emissions; Sustainability; Livestock; Biology; Natural resource economics; Agronomy; Ecology; Pasture; Food science; Fermentation; Bacteria","score_opus":0.013384669354060009,"score_gpt":0.2548118788332682,"score_spread":0.2414272094792082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308178654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97546107,0.003325415,0.019749198,0.0008318714,0.00011937622,0.00038095826,0.00008301105,0.000006091277,0.0000430233],"genre_scores_gemma":[0.9951908,0.00003318728,0.0041494137,0.000018527902,0.00015959895,0.000120801866,0.00012877499,0.000007650914,0.00019124825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994925,0.000018558085,0.000113508606,0.0001651392,0.00007225629,0.00013798797],"domain_scores_gemma":[0.9997759,0.000022097494,0.000044813172,0.000103768754,0.000022125445,0.000031285956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016012629,0.00007840042,0.000079199956,0.000016168302,0.000120506025,0.0000068446293,0.00010341111,0.000045465327,0.0000012606926],"category_scores_gemma":[0.000051707713,0.00005165656,0.000048200964,0.00006370647,0.000024830371,0.0000011102347,0.000101024045,0.00008111369,1.4803961e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002567737,0.000044940254,0.00006243345,0.000023603332,0.000017979852,3.7373707e-7,0.00011521212,0.047944922,0.9500753,0.000029248527,0.0005530274,0.0011072587],"study_design_scores_gemma":[0.0014157929,0.0004814727,0.005675878,0.000023626037,0.000045233348,0.000040481977,0.003179574,0.008300931,0.96952593,0.00006374189,0.011005069,0.00024227818],"about_ca_topic_score_codex":0.000018015582,"about_ca_topic_score_gemma":0.0000159361,"teacher_disagreement_score":0.03964399,"about_ca_system_score_codex":0.0000058833034,"about_ca_system_score_gemma":0.000021994314,"threshold_uncertainty_score":0.21064933},"labels":[],"label_agreement":null},{"id":"W4308370161","doi":"10.1039/d2an01318e","title":"How to detect CRISPR with CRISPR – employing SHERLOCK for doping control purposes","year":2022,"lang":"en","type":"article","venue":"The Analyst","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Sporthochschule Köln; Manfred Donike Institut für Dopinganalytik; World Anti-Doping Agency","keywords":"CRISPR; Genome editing; Computational biology; Guide RNA; Cas9; Trans-activating crRNA; Subgenomic mRNA; Nucleic acid; DNA; Biology; Computer science; Gene; Genetics","score_opus":0.00871881426582139,"score_gpt":0.2748541392129236,"score_spread":0.26613532494710224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308370161","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32799336,0.0016702755,0.66698366,0.0023088623,0.00017839311,0.00066971226,0.000047752957,0.00003075811,0.00011721],"genre_scores_gemma":[0.99661905,0.000012911528,0.0013258706,0.0006343299,0.0003353721,0.00028466422,0.000021197424,0.000032399825,0.00073419465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991572,0.000043692362,0.0001148318,0.00027187305,0.00013991278,0.0002724982],"domain_scores_gemma":[0.9994219,0.0000295203,0.000042779408,0.0003871062,0.000055540957,0.00006313899],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002220641,0.00014016114,0.00015575215,0.000049114104,0.00032721102,0.000063011365,0.0002898985,0.000027350707,0.000008930735],"category_scores_gemma":[0.00004250733,0.00010349365,0.00010936577,0.00015461307,0.00001972703,0.0000024043354,0.0001094975,0.000083931234,0.0000011205805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047778615,0.000026214015,0.0013030192,0.00004593287,0.0005234613,0.0000069406483,0.00025822155,0.06841763,0.91632605,0.000058355716,0.008461154,0.0040952405],"study_design_scores_gemma":[0.0018521156,0.0017476424,0.0011748066,0.000018768795,0.0003928903,0.00006702991,0.0018180679,0.0020307573,0.52337277,0.0000614293,0.46681374,0.00064998755],"about_ca_topic_score_codex":0.000032204778,"about_ca_topic_score_gemma":0.00010729765,"teacher_disagreement_score":0.6686257,"about_ca_system_score_codex":0.00001728803,"about_ca_system_score_gemma":0.00002760859,"threshold_uncertainty_score":0.42203486},"labels":[],"label_agreement":null},{"id":"W4308450593","doi":"10.1038/s41467-022-34390-7","title":"Inducible plasmid copy number control for synthetic biology in commonly used E. coli strains","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"York University; New York University Abu Dhabi","keywords":"Plasmid; Synthetic biology; Biology; Low copy number; Computational biology; Copy-number variation; Cloning (programming); Gene; Escherichia coli; Genetics; Software portability; Origin of replication; Metabolic engineering; Computer science; Genome","score_opus":0.016543624163694544,"score_gpt":0.3487856409655495,"score_spread":0.33224201680185494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308450593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9679585,0.008122117,0.009787728,0.0066054147,0.0006301519,0.0016338915,0.0014910984,0.000064947606,0.0037061435],"genre_scores_gemma":[0.9959112,0.000120674435,0.0022118646,0.00047974978,0.000037860438,0.00047285878,0.0006562522,0.00002257913,0.00008696813],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99920607,0.00013061715,0.0001882926,0.0002107294,0.000059406866,0.00020490606],"domain_scores_gemma":[0.99870884,0.00011834769,0.000051098657,0.0010310669,0.00004888638,0.000041756706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002647492,0.00011038495,0.00014479121,0.00005293557,0.00022537696,0.000010731346,0.0007253717,0.00019892013,0.000035841185],"category_scores_gemma":[0.00011381056,0.00012588828,0.0000726998,0.00014772367,0.00007462,0.0000018701157,0.0002847685,0.00051145745,0.0000024427668],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023915956,0.0010781118,0.100672975,0.000047231984,0.00029423845,0.0000019928243,0.0006351592,0.008937064,0.82135725,0.040922105,0.023297887,0.002516805],"study_design_scores_gemma":[0.0039230646,0.0003798875,0.012532652,0.000014152998,0.000056044122,0.00003242075,0.00054839504,0.004179045,0.033701863,0.00080269633,0.94328284,0.0005469551],"about_ca_topic_score_codex":0.000019624142,"about_ca_topic_score_gemma":0.0005391034,"teacher_disagreement_score":0.91998494,"about_ca_system_score_codex":0.000034151046,"about_ca_system_score_gemma":0.00008130204,"threshold_uncertainty_score":0.5133575},"labels":[],"label_agreement":null},{"id":"W4308527370","doi":"10.1371/journal.pbio.3001874","title":"Virus-derived gene transfer agents benefit host cells by providing templates for DNA repair","year":2022,"lang":"en","type":"letter","venue":"PLoS Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; DNA; Gene transfer; Horizontal gene transfer; Gene; DNA repair; Template; Virus; Computational biology; Genetics; Cell biology; Genome; Nanotechnology","score_opus":0.016711268905492935,"score_gpt":0.27729785806063795,"score_spread":0.260586589155145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308527370","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9168957,0.012442653,0.0143158585,0.03317173,0.0033746187,0.004576197,0.014435844,0.00043054268,0.00035688683],"genre_scores_gemma":[0.23704779,0.008902198,0.009861229,0.5758414,0.019598193,0.0069276043,0.12169487,0.0017191711,0.01840751],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976499,0.000070642556,0.00042424,0.0010335613,0.000121118515,0.00070055434],"domain_scores_gemma":[0.9991499,0.00005918257,0.00007960364,0.0005709946,0.000064397726,0.00007589154],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000120805926,0.0005107564,0.00050373934,0.000094350675,0.00017294846,0.000021032884,0.00046467758,0.0010779443,0.00022670576],"category_scores_gemma":[0.00003475913,0.0005228426,0.0004023208,0.00006856378,0.00007704687,0.000002311503,0.00017960677,0.00052574696,0.00001002509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005063604,0.000035720845,0.000034318247,0.00013244161,0.0003233909,0.000008733745,0.000026313068,0.000024347442,0.69833577,0.0000011460533,0.30094868,0.00007848461],"study_design_scores_gemma":[0.0002944324,0.00044238745,0.0000056046806,0.000008083035,0.000083206956,0.0000071996797,0.0000064734404,0.00006191402,0.50420266,0.0000073080046,0.4945325,0.0003482214],"about_ca_topic_score_codex":0.00002783892,"about_ca_topic_score_gemma":0.000012452641,"teacher_disagreement_score":0.6798479,"about_ca_system_score_codex":0.0000416258,"about_ca_system_score_gemma":0.00005350405,"threshold_uncertainty_score":0.9997223},"labels":[],"label_agreement":null},{"id":"W4308612054","doi":"10.1111/bioe.13105","title":"Rewriting the genetic bond: Gene editing and our understanding of genetic parenthood","year":2022,"lang":"en","type":"article","venue":"Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Offspring; Genetics; Biology; Affect (linguistics); Germline; Developmental psychology; Psychology; Social psychology; Gene; Communication","score_opus":0.048033633620922736,"score_gpt":0.3308024164272849,"score_spread":0.2827687828063622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308612054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9401344,0.009475013,0.047726437,0.0014304342,0.00055264187,0.0003006929,0.000062033076,0.000023666791,0.0002946729],"genre_scores_gemma":[0.9947963,0.00042402736,0.004172427,0.00016222055,0.0003425178,0.000023525094,0.00001875014,0.000027017319,0.000033247343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989468,0.00007884408,0.00025701264,0.00026473208,0.00021905727,0.0002335513],"domain_scores_gemma":[0.99949765,0.000030254329,0.000103251514,0.00028194865,0.00003457023,0.000052333125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004195575,0.00012881086,0.00011791702,0.000039470822,0.00033054085,0.00002213251,0.00019218799,0.00008157059,0.00000487536],"category_scores_gemma":[0.00009642923,0.00011988211,0.000059749673,0.000109646804,0.00009884393,0.0000013851438,0.0003548086,0.00023989669,3.471251e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006894451,0.00009533379,0.050238322,0.0002640912,0.00021588245,0.00002622883,0.0021049066,0.015247394,0.9211648,0.0023322348,0.002113438,0.0061284383],"study_design_scores_gemma":[0.0032069085,0.002099834,0.051356953,0.00013607148,0.0004025294,0.0010186812,0.11677991,0.010275268,0.78582126,0.0033735128,0.02364764,0.00188142],"about_ca_topic_score_codex":0.00003497801,"about_ca_topic_score_gemma":0.000022134065,"teacher_disagreement_score":0.1353435,"about_ca_system_score_codex":0.000022818047,"about_ca_system_score_gemma":0.000054905384,"threshold_uncertainty_score":0.48886505},"labels":[],"label_agreement":null},{"id":"W4308684495","doi":"10.1182/bloodadvances.2022008966","title":"Applying CRISPR-Cas9 screens to dissect hematological malignancies","year":2022,"lang":"en","type":"review","venue":"Blood Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"CRISPR; Context (archaeology); Computational biology; Genome editing; Cas9; Biology; Disease; Epigenomics; Precision medicine; Computer science; Genetics; Gene; Medicine; Pathology; DNA methylation","score_opus":0.030561699196151496,"score_gpt":0.3683949792914444,"score_spread":0.3378332800952929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308684495","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006413345,0.99560267,0.002518898,0.000008855741,0.00027833486,0.0008753705,0.00008340007,0.00010015416,0.00046816192],"genre_scores_gemma":[0.00012635578,0.9948941,0.0024429432,0.00007542201,0.00033164173,0.0015231014,0.00018770766,0.00011510007,0.0003036136],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982054,0.00006505696,0.00040623388,0.0006954832,0.0002014165,0.00042637388],"domain_scores_gemma":[0.9991748,0.000052200623,0.00011638786,0.0004918957,0.000020618387,0.00014411243],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013772104,0.00044357244,0.00087289145,0.0000860327,0.00014528338,0.000033461045,0.0004642746,0.00018602215,0.000054288077],"category_scores_gemma":[0.00014684403,0.00037727848,0.00039426153,0.00022534147,0.000035445388,0.000003009297,0.00041260268,0.00021618628,0.000025310048],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001088681,0.00011316582,0.000031079162,0.0060709855,0.00023897328,0.00008498233,0.000019576046,0.00017209622,0.00073303754,0.00012474008,0.0010264373,0.991374],"study_design_scores_gemma":[0.00009407597,0.0001883094,0.0000023001537,0.0006165936,0.00026645145,0.0002317506,0.00005712564,5.634905e-7,0.0015053886,0.000009479106,0.99653226,0.0004957135],"about_ca_topic_score_codex":0.0000024973808,"about_ca_topic_score_gemma":0.000010256205,"teacher_disagreement_score":0.9955058,"about_ca_system_score_codex":0.000011470124,"about_ca_system_score_gemma":0.000066077126,"threshold_uncertainty_score":0.9998679},"labels":[],"label_agreement":null},{"id":"W4308752107","doi":"10.1002/ggn2.202200014","title":"A CRISPR Path to Finding Vulnerabilities and Solving Drug Resistance: Targeting the Diverse Cancer Landscape and Its Ecosystem","year":2022,"lang":"en","type":"review","venue":"Advanced Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Snow Medical; Cancer Institute NSW","keywords":"CRISPR; Drug resistance; Identification (biology); Tumor microenvironment; Computational biology; Biology; Cancer; Drug discovery; Disease; Genomics; Cancer research; Bioinformatics; Medicine; Genetics; Gene; Genome; Pathology","score_opus":0.017278346857727375,"score_gpt":0.3291246958455428,"score_spread":0.31184634898781544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308752107","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007250396,0.99092627,0.0003302505,0.000038382837,0.0004154295,0.00071635,0.00021591235,0.000019171373,0.00008786162],"genre_scores_gemma":[0.0042713745,0.99272865,0.0011024309,0.00005483136,0.00030184764,0.0003600068,0.00008116781,0.00008166321,0.0010180454],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982058,0.00012826052,0.00040571025,0.0006652651,0.00018424977,0.0004107578],"domain_scores_gemma":[0.9991608,0.00012499654,0.00015899859,0.00037654862,0.000047058533,0.00013158807],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003184329,0.00041609953,0.00058583764,0.00006905265,0.00040261608,0.00006338784,0.0002827263,0.00012836454,0.000031793825],"category_scores_gemma":[0.00014792173,0.00034104535,0.00012610597,0.0001558292,0.000026931575,0.000004205977,0.0006002921,0.00028130497,0.0000013872356],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070701986,0.000043354543,0.00017862945,0.03407987,0.0005928598,0.00003227985,0.003115786,0.0079201255,0.0043072863,0.000103400154,0.0070316335,0.9425241],"study_design_scores_gemma":[0.0001573806,0.000044273405,0.0000047976096,0.0009850606,0.00018562452,0.0000127099265,0.00084281916,0.000093974,0.00058638817,0.0000072746243,0.99662787,0.0004518051],"about_ca_topic_score_codex":0.000003209616,"about_ca_topic_score_gemma":0.00012760586,"teacher_disagreement_score":0.98959625,"about_ca_system_score_codex":0.0000410746,"about_ca_system_score_gemma":0.00009235512,"threshold_uncertainty_score":0.99990416},"labels":[],"label_agreement":null},{"id":"W4308913774","doi":"10.15252/msb.202110886","title":"Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells","year":2022,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Toronto","funders":"Canadian Institutes of Health Research; ETH Zürich Foundation; Canada First Research Excellence Fund; Canada Research Chairs; Royal Academy of Engineering; Banting Research Foundation; Stavros Niarchos Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Toronto; Michael Smith Health Research BC; National Science Foundation","keywords":"Biology; Induced pluripotent stem cell; Cell biology; Stem cell; Computational biology; Gene; Genetics; Embryonic stem cell","score_opus":0.006967167043624431,"score_gpt":0.24694619173557625,"score_spread":0.23997902469195181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308913774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8601988,0.0031430542,0.13545386,0.000010065991,0.00023179919,0.00086922,0.000038419716,0.000014776991,0.000039998566],"genre_scores_gemma":[0.99877787,0.000015660551,0.00009019744,0.00002383601,0.000042876494,0.00065967906,0.00003902388,0.00003760999,0.00031323187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986727,0.00018327861,0.00028137502,0.00047332977,0.00006925684,0.0003200484],"domain_scores_gemma":[0.9995586,0.000007593422,0.000085089014,0.0002595214,0.000029989731,0.000059179558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034962385,0.00017138929,0.00020153154,0.00010990698,0.0001335048,0.000017475826,0.00013378038,0.00009781926,0.0000017775137],"category_scores_gemma":[0.000005959129,0.00019204765,0.00006140613,0.00008070036,0.00003022523,0.0000014480701,0.00014801108,0.000112046044,6.045832e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017248458,0.000028564813,0.000065114,0.0000929991,0.000020641985,0.000009882766,0.000058722428,0.008750926,0.9895641,0.000023264163,0.000004645342,0.0013638744],"study_design_scores_gemma":[0.00069412496,0.00067379524,0.000044051245,0.000010992962,0.000010796512,0.000039967024,0.00012396573,0.0029365653,0.98925656,0.00002447672,0.0059512667,0.00023344532],"about_ca_topic_score_codex":0.00007574633,"about_ca_topic_score_gemma":0.00001730617,"teacher_disagreement_score":0.13857909,"about_ca_system_score_codex":0.00004154191,"about_ca_system_score_gemma":0.000023187005,"threshold_uncertainty_score":0.78314763},"labels":[],"label_agreement":null},{"id":"W4309018553","doi":"10.1093/neuonc/noac209.1144","title":"MODL-16. SOMATICALLY ENGINEERED MOUSE MODELS RECAPITULATING CELLULAR AND MOLECULAR FEATURES OF HUMAN GBM","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"PTEN; Biology; CDKN2A; Cancer research; PDGFRA; Context (archaeology); Phenotype; Mesenchymal stem cell; Pathology; Stromal cell; PI3K/AKT/mTOR pathway; Gene; Genetics; Medicine; Signal transduction","score_opus":0.009580931457660003,"score_gpt":0.2737601221694131,"score_spread":0.2641791907117531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309018553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9779403,0.001267377,0.01859536,0.00016443238,0.00013029126,0.00023645717,0.00002266242,0.000028268185,0.0016148427],"genre_scores_gemma":[0.9969401,0.000050417657,0.0024262539,0.00026820222,0.00006832647,0.000051177176,0.0000729643,0.000045944074,0.00007662657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987482,0.00013054899,0.00030483777,0.00037209288,0.00016665229,0.00027765747],"domain_scores_gemma":[0.9993793,0.000039213417,0.000091199174,0.0003474306,0.000044515782,0.000098365344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018336454,0.00018514911,0.00027651145,0.00008094314,0.000115011324,0.0000095610785,0.00021094196,0.00013782672,0.000027728296],"category_scores_gemma":[0.00006329637,0.00021003926,0.000090297915,0.00008542443,0.000064241074,0.000003489999,0.0003622734,0.00024711035,4.336185e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032100197,0.000069542984,0.00003189353,0.000037412938,0.000036807593,0.000024549092,0.00017243136,0.041620042,0.95549405,0.0007908076,0.000339807,0.0013505822],"study_design_scores_gemma":[0.00073278305,0.0010518484,0.00004294848,0.0000033474353,0.000036384055,0.00007423877,0.00017784498,0.005215398,0.9878184,0.00056028663,0.0040706173,0.00021590813],"about_ca_topic_score_codex":0.000015370644,"about_ca_topic_score_gemma":0.000005476857,"teacher_disagreement_score":0.036404643,"about_ca_system_score_codex":0.000032143973,"about_ca_system_score_gemma":0.000055940196,"threshold_uncertainty_score":0.8565153},"labels":[],"label_agreement":null},{"id":"W4309264060","doi":"10.1016/j.xpro.2022.101861","title":"Protocol to measure end resection intermediates at sequence-specific DNA double-strand breaks by quantitative polymerase chain reaction using ER-AsiSI U2OS cells","year":2022,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Polymerase chain reaction; Chemistry; DNA; Molecular biology; Sequence (biology); Polymerase; Biology; Biochemistry; Gene","score_opus":0.05015546539777878,"score_gpt":0.3685787796134457,"score_spread":0.31842331421566694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309264060","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36985704,0.000061676685,0.0060087442,0.00012220067,0.00022030911,0.62288713,0.00037089363,0.000054918528,0.00041708144],"genre_scores_gemma":[0.21006237,0.0000021234355,0.0010219525,0.000063971704,0.00018695336,0.7878912,0.00015514587,0.00006249364,0.0005537999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99816066,0.00015266503,0.0003501616,0.0005952689,0.0003547802,0.00038643827],"domain_scores_gemma":[0.9992214,0.000014312745,0.00013373005,0.00038480602,0.00009151897,0.0001542739],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042035748,0.00026904445,0.00020498302,0.00010818371,0.00030864694,0.000052804116,0.00021659977,0.0001138639,0.0002052576],"category_scores_gemma":[0.00001644089,0.00028315687,0.00009943266,0.0002306516,0.00005443081,0.000012164402,0.0001987365,0.0002199123,0.000012824131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030017858,0.00010397226,0.00006963047,0.000088657645,0.000036353496,0.000005245134,0.00032374545,0.00095169945,0.99191076,0.000008806217,0.0023852922,0.0011140265],"study_design_scores_gemma":[0.0019134646,0.0012889898,0.00003726371,0.00004416308,0.0000067795863,0.000022542332,0.00025183658,0.00017122344,0.8606821,0.000009110819,0.13527654,0.00029604443],"about_ca_topic_score_codex":0.00011799057,"about_ca_topic_score_gemma":0.00009928793,"teacher_disagreement_score":0.16500407,"about_ca_system_score_codex":0.0002051655,"about_ca_system_score_gemma":0.0000930517,"threshold_uncertainty_score":0.99996203},"labels":[],"label_agreement":null},{"id":"W4309269409","doi":"10.3390/ijms232214142","title":"Simultaneous Inhibition of Histone Deacetylases and RNA Synthesis Enables Totipotency Reprogramming in Pig SCNT Embryos","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Somatic cell nuclear transfer; Reprogramming; Biology; Chromatin; Histone; Cell biology; Blastocyst; Histone deacetylase; Somatic cell; Embryo; Molecular biology; Genetics; Embryogenesis; Gene","score_opus":0.00722407009593315,"score_gpt":0.30354553431566145,"score_spread":0.29632146421972827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309269409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902787,0.0035635834,0.0056174034,0.00020796085,0.00017954498,0.000041319014,0.000004892383,0.0000016086739,0.00010494462],"genre_scores_gemma":[0.9969285,0.00022113459,0.0027410376,0.000044479013,0.000040607174,0.0000040185546,0.0000016794951,0.000004855725,0.000013678591],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905306,0.000047399826,0.00028227302,0.00014254401,0.00037834904,0.00009636277],"domain_scores_gemma":[0.99958014,0.000041446223,0.00017178919,0.00006203153,0.0001122478,0.000032369655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048335572,0.000065160886,0.00009980021,0.00017704302,0.00004595505,0.000020410438,0.00021708733,0.000021788928,0.000012173963],"category_scores_gemma":[0.00034019572,0.0000633336,0.00005876015,0.00010719485,0.00009597945,0.000007904679,0.00012743726,0.000070955844,8.434321e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042027645,0.000061010123,0.0005507389,0.0000063323896,0.000026392392,0.00012733051,0.00010107223,0.05854589,0.92128307,0.00006836105,0.0000129470955,0.019174824],"study_design_scores_gemma":[0.00029938138,0.00039603031,0.00047794302,0.0000522675,0.000012694437,0.00043140803,0.0006942251,0.0013646486,0.99512255,0.00018661885,0.00085739716,0.000104842766],"about_ca_topic_score_codex":0.000033584805,"about_ca_topic_score_gemma":0.000009958413,"teacher_disagreement_score":0.07383947,"about_ca_system_score_codex":0.00002749892,"about_ca_system_score_gemma":0.00007256922,"threshold_uncertainty_score":0.25826693},"labels":[],"label_agreement":null},{"id":"W4309370218","doi":"10.1016/j.jbc.2022.102728","title":"rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Simons Foundation","keywords":"Haploinsufficiency; Adeno-associated virus; Genetic enhancement; Allele; Biology; Internal medicine; Endocrinology; Cancer research; Medicine; Genetics; Gene; Vector (molecular biology); Recombinant DNA; Phenotype","score_opus":0.00827864266332286,"score_gpt":0.26968229458504384,"score_spread":0.261403651921721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309370218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805604,0.018729873,0.0001418017,0.00018899982,0.00010500143,0.00008229807,0.000019714129,0.000006599752,0.00016530119],"genre_scores_gemma":[0.99748445,0.0018480938,0.00015901859,0.00016892074,0.000107330394,0.000010672126,0.00001327167,0.000011685494,0.00019655276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990141,0.00007217572,0.0002737615,0.00025900433,0.00015520156,0.00022578132],"domain_scores_gemma":[0.99949837,0.000038633403,0.00012832138,0.00012856274,0.000059360747,0.00014673057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029028216,0.00016356779,0.00022253949,0.00003674881,0.000090473666,0.000019005402,0.00023187531,0.00010256535,0.000043947024],"category_scores_gemma":[0.00020504586,0.00012961258,0.000114733004,0.00013399235,0.00008096566,0.000003913508,0.00015098073,0.0003874989,2.5064918e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006021686,0.0002131987,0.015357784,0.000022061397,0.00004215619,0.00019298418,0.000076274344,0.0008593813,0.98042303,0.0000013519245,0.001124526,0.001085061],"study_design_scores_gemma":[0.0020070444,0.001716989,0.19779845,0.00004117945,0.000024970586,0.0019787666,0.00069678243,0.0000685235,0.77960557,0.00012892847,0.015434475,0.000498301],"about_ca_topic_score_codex":0.0000039027173,"about_ca_topic_score_gemma":5.99807e-7,"teacher_disagreement_score":0.20081745,"about_ca_system_score_codex":0.00003548822,"about_ca_system_score_gemma":0.00010082342,"threshold_uncertainty_score":0.5285448},"labels":[],"label_agreement":null},{"id":"W4309412933","doi":"10.17912/micropub.biology.000657","title":"A new combinatorial megaplasmid library assembly method designed to screen for minimal pathways by using SCRaMbLE","year":2022,"lang":"en","type":"article","venue":"PubMed","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Complementary DNA; Computational biology; Streptavidin; cDNA library; Yeast; Biology; Genomic library; Saccharomyces cerevisiae; Synthetic biology; Gene; Genetics; Base sequence; Biotin","score_opus":0.019553350425773653,"score_gpt":0.2767560750601619,"score_spread":0.25720272463438826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309412933","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3077821,0.0012855128,0.6865387,0.00035872916,0.001103712,0.0018263296,0.00030840526,0.00007012516,0.0007263882],"genre_scores_gemma":[0.86993486,0.000013457875,0.12449775,0.0006451107,0.0008502919,0.0018250865,0.00035652626,0.00010786696,0.001769047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880975,0.00006315139,0.0001809615,0.0003693189,0.00015320694,0.00042358253],"domain_scores_gemma":[0.9994439,0.000033672834,0.000042539057,0.00022303901,0.00001843409,0.00023841616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029260063,0.0001542435,0.00016133454,0.000054064425,0.00014350856,0.00004889465,0.0002601401,0.00007532631,0.000022490558],"category_scores_gemma":[0.00006648745,0.00017946372,0.00010106086,0.00014644778,0.000006447878,0.0000064270566,0.00028405595,0.00007391649,7.4212505e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005644041,0.00006924587,0.0001224716,0.00001786849,0.00008867509,0.0000026437951,0.000047021033,0.001934158,0.8221212,0.00020915773,0.13103339,0.043789793],"study_design_scores_gemma":[0.0015260675,0.00033576554,0.00039150182,0.0000018559598,0.000039766655,0.000010938133,0.00005652433,0.0011074694,0.7357989,0.00013111472,0.26025808,0.00034200796],"about_ca_topic_score_codex":0.000024615361,"about_ca_topic_score_gemma":0.0000010111481,"teacher_disagreement_score":0.56215274,"about_ca_system_score_codex":0.000023188904,"about_ca_system_score_gemma":0.00009467448,"threshold_uncertainty_score":0.73183185},"labels":[],"label_agreement":null},{"id":"W4309437992","doi":"10.1038/s41467-022-34269-7","title":"High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Chromatin; Histone; Computational biology; Biology; Gene silencing; Epigenetics; Regulation of gene expression; CRISPR; Genetics; Cell biology; Gene","score_opus":0.009336897012646266,"score_gpt":0.3322601715175582,"score_spread":0.32292327450491193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309437992","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6292772,0.0065109883,0.36291006,0.00043377533,0.00020223383,0.0004641046,0.00014903184,0.000027181046,0.000025359988],"genre_scores_gemma":[0.9709898,0.00018121609,0.027952287,0.00004869818,0.000033920514,0.0001872991,0.0005659698,0.000016424827,0.000024375408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944705,0.00006459847,0.00016595371,0.00017368916,0.00006033136,0.000088383225],"domain_scores_gemma":[0.99894303,0.0000619344,0.00008990373,0.0007759118,0.000099747325,0.00002944357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019978048,0.00008519505,0.00010692592,0.00005978895,0.00022454368,0.0000047561234,0.00023363816,0.000114902454,0.0000027839158],"category_scores_gemma":[0.00016422832,0.00009655464,0.000054976295,0.000107600405,0.000034973404,0.0000027275582,0.00018136,0.00022174983,5.5376095e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005825457,0.00005308825,0.0000040827367,0.000012679276,0.000019349589,1.6788192e-8,0.00003385897,0.003979909,0.9930566,0.000054473396,0.00006168473,0.0026660059],"study_design_scores_gemma":[0.0005803409,0.00017635745,0.0011293695,0.0000030011324,0.000029361996,0.0000013957783,0.00002444012,0.009409223,0.98287374,0.000040621708,0.005632656,0.000099515026],"about_ca_topic_score_codex":0.000014885695,"about_ca_topic_score_gemma":0.00006313308,"teacher_disagreement_score":0.34171256,"about_ca_system_score_codex":0.000029112254,"about_ca_system_score_gemma":0.000032038297,"threshold_uncertainty_score":0.3937384},"labels":[],"label_agreement":null},{"id":"W4309694247","doi":"10.1016/j.neuron.2022.10.035","title":"TEMPO enables sequential genetic labeling and manipulation of vertebrate cell lineages","year":2022,"lang":"en","type":"article","venue":"Neuron","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Howard Hughes Medical Institute","keywords":"Vertebrate; Biology; Neuroscience; Evolutionary biology; Communication; Genetics; Computational biology; Gene; Psychology","score_opus":0.009040962386328502,"score_gpt":0.2535551727190188,"score_spread":0.24451421033269027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309694247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968661,0.0013917633,0.001371268,0.00001981408,0.00013031742,0.000068818605,0.0000083744835,0.0000064860938,0.00013704252],"genre_scores_gemma":[0.9989382,0.00015483223,0.00055507757,0.00004325041,0.00006635167,0.000006758846,0.000030377898,0.0000137211955,0.0001914494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999555,0.000027218972,0.00010512657,0.00015391238,0.000070221446,0.00008853909],"domain_scores_gemma":[0.9998149,0.0000039949837,0.00003164121,0.0001145215,0.000012641664,0.000022280523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045938617,0.00006294322,0.000058513087,0.000025092655,0.000053274096,0.0000062993286,0.000055786353,0.000023877192,0.000019475136],"category_scores_gemma":[0.0000066927955,0.00007152093,0.00002203766,0.0000359774,0.000011744793,0.0000010919927,0.00010803302,0.000048293,4.6805198e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013099282,0.000014296687,0.0027901237,0.00002950598,0.0000043715618,0.000002154159,0.000027063496,0.023030253,0.97331357,0.0000039078373,0.00011422126,0.000657456],"study_design_scores_gemma":[0.00037407095,0.00033009172,0.009206149,0.0000027388644,0.000018181232,0.00001505415,0.000048498423,0.006741038,0.9756603,0.000013836876,0.007474829,0.000115193005],"about_ca_topic_score_codex":0.000012445866,"about_ca_topic_score_gemma":0.000003087483,"teacher_disagreement_score":0.016289216,"about_ca_system_score_codex":0.0000030088422,"about_ca_system_score_gemma":0.000011575057,"threshold_uncertainty_score":0.29165387},"labels":[],"label_agreement":null},{"id":"W4309857868","doi":"10.3390/biomedicines10123028","title":"Coupling CRISPR/Cas9 and Lambda Red Recombineering System for Genome Editing of Salmonella Gallinarum and the Effect of ssaU Knock-Out Mutant on the Virulence of Bacteria","year":2022,"lang":"en","type":"article","venue":"Biomedicines","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"International Development Research Centre","keywords":"Virulence; Biology; CRISPR; Salmonella; Microbiology; Recombineering; Type three secretion system; Pathogenicity island; Plasmid; Genome; Mutant; Genome editing; Effector; Cas9; Genomic island; Genetics; Gene; Bacteria; Cell biology","score_opus":0.006331790869373532,"score_gpt":0.25212491960481875,"score_spread":0.24579312873544523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309857868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99527013,0.0024674854,0.0012772623,0.00018251035,0.00032089226,0.00040732743,0.00004564769,0.0000052604087,0.000023490062],"genre_scores_gemma":[0.99949414,0.00016683708,0.00008166661,0.0000071290087,0.00015236913,0.000052705363,0.000015506439,0.000014939424,0.000014701399],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928457,0.000040316816,0.00027628383,0.00016522566,0.00011129453,0.00012231535],"domain_scores_gemma":[0.9993807,0.00020738567,0.00014979836,0.00019881794,0.00003876206,0.000024523066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078241905,0.00011520693,0.00026071465,0.000042596468,0.0000786889,0.0000039038396,0.00012398644,0.000037975617,0.0000023033951],"category_scores_gemma":[0.00011972706,0.00006949014,0.000051392315,0.00006961407,0.00013833818,0.0000012284679,0.00011817392,0.000053264765,2.85498e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003294083,0.000006443411,0.00047531622,0.00059541187,0.00005548847,6.177854e-7,0.0001645491,0.0004641246,0.9975958,0.00003154589,0.000029944378,0.00025137095],"study_design_scores_gemma":[0.0018907462,0.0017258393,0.0013673299,0.00022228963,0.00009729447,0.000028651031,0.0013242734,0.006317919,0.98595846,0.0000071292,0.0009464136,0.00011367113],"about_ca_topic_score_codex":0.000017738106,"about_ca_topic_score_gemma":0.0000014125384,"teacher_disagreement_score":0.011637336,"about_ca_system_score_codex":0.0000067289584,"about_ca_system_score_gemma":0.000009416934,"threshold_uncertainty_score":0.28337255},"labels":[],"label_agreement":null},{"id":"W4310060405","doi":"10.1038/s41596-022-00773-9","title":"Optimized prime editing in monocot plants using PlantPegDesigner and engineered plant prime editors (ePPEs)","year":2022,"lang":"en","type":"review","venue":"Nature Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Prime (order theory); Computer science; Construct (python library); Protocol (science); Rice plant; Computational biology; Biotechnology; Biology; Mathematics; Programming language; Agronomy","score_opus":0.029353713549659363,"score_gpt":0.3789345485147056,"score_spread":0.3495808349650462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310060405","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000424165,0.9435668,0.0013657656,0.000005151715,0.0009990066,0.053451408,0.00042068167,0.000047951784,0.000100812395],"genre_scores_gemma":[0.000050898503,0.8897815,0.01002964,0.000045109326,0.008238186,0.08934712,0.0020734768,0.00029529055,0.00013880641],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975865,0.00016127784,0.0006267015,0.00079502526,0.00029723148,0.0005332812],"domain_scores_gemma":[0.9990352,0.00008375349,0.00026518683,0.0004596908,0.000021569667,0.0001346349],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047890167,0.0006279308,0.0011279376,0.00025466701,0.00009213174,0.000063545966,0.0004071566,0.0012139825,0.000028467495],"category_scores_gemma":[0.00015605215,0.00057674694,0.00021735055,0.00018152822,0.000029898747,0.000006515048,0.00033807906,0.0013652921,0.0000014286287],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010146494,0.0006954803,0.000119219636,0.04041745,0.001683221,0.0006355519,0.00039365655,0.0054386887,0.021471605,0.00003855836,0.01514392,0.912948],"study_design_scores_gemma":[0.0008826139,0.00012649962,0.000003037251,0.003280877,0.00008353688,0.00020325145,0.000012688799,0.0003999241,0.0036800245,0.0000023679404,0.9906962,0.0006289726],"about_ca_topic_score_codex":0.000009475241,"about_ca_topic_score_gemma":0.000002192449,"teacher_disagreement_score":0.97555226,"about_ca_system_score_codex":0.000092232534,"about_ca_system_score_gemma":0.00025906702,"threshold_uncertainty_score":0.9996684},"labels":[],"label_agreement":null},{"id":"W4310102492","doi":"10.1021/acscentsci.2c00836","title":"nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei","year":2022,"lang":"en","type":"article","venue":"ACS Central Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Phenotype; Computational biology; Cas9; Genetic screen; Genome; Context (archaeology); Subcellular localization; Function (biology); Cell biology; Genetics; Gene; Cytoplasm","score_opus":0.010126627377119366,"score_gpt":0.25139989385438033,"score_spread":0.24127326647726097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310102492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89062095,0.0021017536,0.10642226,0.00009882582,0.0003050358,0.00023801198,0.000023752335,0.000017196015,0.00017224683],"genre_scores_gemma":[0.9965912,0.000082156424,0.0026197752,0.0002555652,0.00013701417,0.000029557777,0.000058564663,0.000017245644,0.00020890145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986424,0.0000076034316,0.00014215113,0.00038975387,0.0002211181,0.0005969711],"domain_scores_gemma":[0.9995162,0.00001023486,0.000037874728,0.0002627946,0.000035069894,0.00013785578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030640105,0.00011572627,0.000086353655,0.000047421596,0.00051372405,0.00004097721,0.0005193116,0.000032108324,0.000042838168],"category_scores_gemma":[0.00005350366,0.00012404907,0.000063253545,0.00022793545,0.000115367715,0.000007758699,0.00032583266,0.00008525475,0.000002607173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002173345,0.000017364468,0.0013865965,0.0000066963926,0.0000071954537,0.0000014103579,0.000105702944,0.0017534499,0.99358803,0.000072866904,0.00068501185,0.0023539646],"study_design_scores_gemma":[0.00035510265,0.00013063432,0.007138635,0.0000023261946,0.0000104814635,0.000008375418,0.00021717019,0.0006090697,0.83777165,0.0000575818,0.15347491,0.00022403302],"about_ca_topic_score_codex":0.000012107214,"about_ca_topic_score_gemma":0.000001535299,"teacher_disagreement_score":0.15581633,"about_ca_system_score_codex":0.00004449772,"about_ca_system_score_gemma":0.000095011084,"threshold_uncertainty_score":0.5058574},"labels":[],"label_agreement":null},{"id":"W4310340633","doi":"10.1101/2022.11.28.518141","title":"Noncannonical functions of Ku may underlie essentiality in human cells","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Ku70; Telomere; Biology; Ku80; DNA repair; Knockout mouse; Cell biology; Molecular biology; Genetics; DNA; Gene; DNA-binding protein; Transcription factor","score_opus":0.011923508431311725,"score_gpt":0.27245889890799,"score_spread":0.2605353904766783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310340633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99227506,0.0009777517,0.004951818,0.000051621802,0.0009922677,0.0003738377,0.00028651193,0.000044191755,0.000046969628],"genre_scores_gemma":[0.9985847,0.00014674662,0.00071472774,0.000037737067,0.00028294305,0.00011714147,0.0000038367743,0.000077276505,0.000034928198],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979741,0.00011361671,0.0005303301,0.0007672304,0.0002427731,0.00037196878],"domain_scores_gemma":[0.9983942,0.000014414431,0.00020205956,0.001136056,0.00012503703,0.0001282485],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042942257,0.00034104232,0.00039569344,0.00015900661,0.00008947096,0.00003507504,0.00045307845,0.00041005504,0.0001351551],"category_scores_gemma":[0.000042657404,0.00042614408,0.00019223214,0.00024777921,0.00010144824,0.0000033388008,0.00080989656,0.0005616952,0.000004760401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019977972,0.00017144944,0.0044730795,0.00022025833,0.00008829112,0.000010906355,0.000003627798,0.0048124776,0.9896743,0.000116385614,0.0004083737,8.2541015e-7],"study_design_scores_gemma":[0.00058630464,0.00009890755,0.040317625,0.00006239174,0.00006510802,1.4042973e-8,0.000008323972,0.000092729475,0.94307506,0.0000013437048,0.01517697,0.00051521935],"about_ca_topic_score_codex":0.00012108335,"about_ca_topic_score_gemma":0.000024153114,"teacher_disagreement_score":0.046599284,"about_ca_system_score_codex":0.00009687836,"about_ca_system_score_gemma":0.00036400795,"threshold_uncertainty_score":0.99981904},"labels":[],"label_agreement":null},{"id":"W4310436379","doi":"10.1038/s41467-022-35175-8","title":"Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression","year":2022,"lang":"en","type":"erratum","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences","keywords":"CRISPR; Psychological repression; Histone; Epigenetics; DNA methylation; Methylation; Computational biology; Gene; Biology; Genetics; Cell biology; Gene expression","score_opus":0.011564708167522935,"score_gpt":0.3454152807280859,"score_spread":0.333850572560563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310436379","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016375162,0.08149735,0.8538635,0.0020821705,0.040342305,0.003206293,0.0015353953,0.0002183573,0.0008794878],"genre_scores_gemma":[0.965691,0.0018496163,0.015901996,0.00006127059,0.00047548825,0.00048338785,0.009028837,0.00008066819,0.006427768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987803,0.00012815284,0.00037094555,0.00042104884,0.00013084423,0.00016871943],"domain_scores_gemma":[0.9975679,0.00012135436,0.0003068535,0.0016547036,0.00028640547,0.00006278888],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030620332,0.00025483698,0.00031447108,0.00016093784,0.00032363558,0.000015385576,0.00046403776,0.0008712861,0.000010608523],"category_scores_gemma":[0.00059250195,0.00029091688,0.00015618106,0.00020006308,0.00007588184,0.000004841714,0.000279314,0.0010490703,1.7168247e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008837081,0.000079804384,7.308519e-7,0.00008082245,0.00007850176,5.953232e-8,0.00004040603,0.00097458815,0.9506823,0.000012571683,0.044062708,0.0038991263],"study_design_scores_gemma":[0.0005093594,0.0002772681,0.00044961367,0.00003326811,0.00014376403,0.0000034155462,0.00002359061,0.011600553,0.70341873,0.00001800534,0.2832472,0.00027524054],"about_ca_topic_score_codex":0.000038143648,"about_ca_topic_score_gemma":0.0003029987,"teacher_disagreement_score":0.9493158,"about_ca_system_score_codex":0.00009022359,"about_ca_system_score_gemma":0.00015863587,"threshold_uncertainty_score":0.9999543},"labels":[],"label_agreement":null},{"id":"W4310500218","doi":"10.1007/978-981-19-5642-3_3","title":"Genome Editing and Cardiac Regeneration","year":2022,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"","keywords":"Regeneration (biology); Genome editing; Biology; Neuroscience; Computational biology; Genome; Cell biology; Gene; Genetics","score_opus":0.009621179297393282,"score_gpt":0.3523377801673284,"score_spread":0.34271660086993516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310500218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8325343,0.1660303,0.00037103746,0.00017048007,0.00034922786,0.000080413214,0.000004749543,0.000004338437,0.00045515885],"genre_scores_gemma":[0.9953454,0.0036509228,0.00028155648,0.00014497356,0.00039070437,0.000047484973,0.000093513496,0.0000057026873,0.000039735984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995282,0.00003381415,0.00010266401,0.00019700572,0.000028917073,0.00010937592],"domain_scores_gemma":[0.9998733,0.000008060818,0.000021251262,0.00006463412,0.0000047250032,0.000028060193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009873451,0.00007103343,0.00009977664,0.00003433851,0.00006922886,0.0000016276676,0.000036516012,0.000026407728,0.000016635335],"category_scores_gemma":[0.000013686504,0.00006404213,0.000009583094,0.000037670306,0.00008596281,0.0000029957064,0.00011232242,0.000051951003,1.01773786e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015221345,0.0000086647315,0.0043568085,0.000004172434,0.000004225167,8.920743e-7,0.00018901932,0.00008882518,0.98963207,0.00022401934,0.000024714123,0.00545134],"study_design_scores_gemma":[0.0015786134,0.0029975106,0.0042103776,0.000013240762,0.000011449931,0.00006618151,0.008034677,0.00019411957,0.52210784,0.0003904608,0.46004522,0.000350336],"about_ca_topic_score_codex":0.000011454498,"about_ca_topic_score_gemma":0.000004004633,"teacher_disagreement_score":0.4675243,"about_ca_system_score_codex":0.000008404664,"about_ca_system_score_gemma":0.0000039215097,"threshold_uncertainty_score":0.2611562},"labels":[],"label_agreement":null},{"id":"W4310500221","doi":"10.1007/978-981-19-5642-3_15","title":"Genome Editing and Protein Energy Malnutrition","year":2022,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Malnutrition; Biofortification; Biotechnology; Biology; Assimilation (phonology); Nutrient; Medicine; Micronutrient","score_opus":0.00865718102924157,"score_gpt":0.337657686571384,"score_spread":0.32900050554214244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310500221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8918192,0.10590635,0.0008863203,0.00025554674,0.0001712956,0.000108220695,0.000005719175,0.0000068292943,0.00084056164],"genre_scores_gemma":[0.9971052,0.0018258924,0.0003141845,0.0002117694,0.00026975432,0.00010798981,0.00008214754,0.0000065438,0.00007651798],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99948275,0.000031977906,0.000113201626,0.00021255856,0.00003118021,0.0001283177],"domain_scores_gemma":[0.9998706,0.0000062694717,0.000024799132,0.0000616805,0.000004873952,0.000031785265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007212193,0.00007996588,0.000098282595,0.000045422334,0.000063432984,0.000001576042,0.00004477101,0.000031176165,0.000026931551],"category_scores_gemma":[0.000010833071,0.00006555253,0.000009042469,0.000044009437,0.00010496567,0.0000032754645,0.00012981959,0.000051672647,6.673761e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033695287,0.00002116724,0.00071244966,0.0000077719815,0.0000034414104,0.0000028527384,0.00008427832,0.000018195702,0.9938044,0.0004185973,0.000017569286,0.004875573],"study_design_scores_gemma":[0.0020166761,0.0033005094,0.0005936211,0.000023526693,0.000005333311,0.00018715627,0.0041698692,0.000100532554,0.45206195,0.0008901113,0.53637606,0.00027466385],"about_ca_topic_score_codex":0.000021291587,"about_ca_topic_score_gemma":0.000008516354,"teacher_disagreement_score":0.54174244,"about_ca_system_score_codex":0.000008765286,"about_ca_system_score_gemma":0.0000036405663,"threshold_uncertainty_score":0.26731545},"labels":[],"label_agreement":null},{"id":"W4310500277","doi":"10.1007/978-981-19-5642-3_2","title":"Online Databases of Genome Editing in Cardiovascular and Metabolic Diseases","year":2022,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Genome editing; CRISPR; Computer science; Population; Computational biology; Gene; Bioinformatics; Data science; Biology; Medicine; Genetics","score_opus":0.014894382082898531,"score_gpt":0.3609337807385113,"score_spread":0.3460393986556128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310500277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6074732,0.3921688,0.00012228431,0.000023879093,0.000082586215,0.000059308128,0.000036664005,0.0000016424315,0.000031615076],"genre_scores_gemma":[0.9872955,0.011920143,0.00027813794,0.00008430487,0.00015591316,0.000030092317,0.0002267439,0.0000059613703,0.0000031683012],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99939793,0.000046625562,0.00016478544,0.00022402653,0.00004469734,0.00012195743],"domain_scores_gemma":[0.9998048,0.000016213058,0.000027684593,0.000115233095,0.000005435764,0.000030645206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095156,0.00008544209,0.00022841766,0.00007292726,0.000024619332,5.739067e-7,0.00005685989,0.000017426573,0.000013014833],"category_scores_gemma":[0.00003634679,0.00007485187,0.000023047274,0.00007498645,0.0001432272,0.0000042435354,0.00018879844,0.000054982323,2.1618948e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072776034,0.00016304888,0.06771386,0.00004258917,0.000049878836,0.000010793422,0.0003245572,0.0011371725,0.91581607,0.00026583602,0.000008851289,0.014394569],"study_design_scores_gemma":[0.008954055,0.0039947596,0.10699039,0.00011667237,0.00012720775,0.00024608822,0.03256867,0.0005340046,0.34515828,0.000268158,0.5001613,0.00088043854],"about_ca_topic_score_codex":0.00008103937,"about_ca_topic_score_gemma":0.00003080257,"teacher_disagreement_score":0.5706578,"about_ca_system_score_codex":0.000004808746,"about_ca_system_score_gemma":0.000006444173,"threshold_uncertainty_score":0.30523708},"labels":[],"label_agreement":null},{"id":"W4311098240","doi":"10.1158/1538-7445.cancepi22-pr004","title":"Abstract PR004: High-density CRISPR screens reveal mechanisms of chromatin regulation of stemness networks in acute myeloid leukemia","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Biology; Chromatin; CRISPR; Epigenetics; Myeloid leukemia; Cancer research; Genetics; Cell biology; Gene","score_opus":0.0207354049729865,"score_gpt":0.35167746133633937,"score_spread":0.3309420563633529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311098240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99102974,0.0006326534,0.0077132643,0.00006211198,0.0001261946,0.0002887628,0.00005108737,0.0000051233555,0.00009106248],"genre_scores_gemma":[0.998892,0.00015939277,0.00036967345,0.000010757142,0.00008274153,0.00008561814,0.00008149943,0.00002044051,0.00029786248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867594,0.000109872715,0.00027777115,0.0002672119,0.0003862855,0.00028290672],"domain_scores_gemma":[0.9993633,0.000021972273,0.00007757683,0.0003318373,0.0001547011,0.000050583447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008450053,0.00009319728,0.0001865546,0.00011420541,0.000078318575,0.0000059173,0.00023993671,0.00009011594,0.000094644114],"category_scores_gemma":[0.000027881366,0.00010287592,0.00005067317,0.0003026722,0.00006451585,0.0000034698855,0.00028293903,0.00027286846,3.888856e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016589914,0.000025519787,0.00037141485,0.00008010867,0.00003575215,0.0000038122353,0.000057021854,0.056899507,0.939486,0.00014318243,0.0008296415,0.0019021158],"study_design_scores_gemma":[0.0004713978,0.00020589556,0.08792498,0.000041383853,0.000008034644,0.0000035224934,0.00015045093,0.0011213422,0.9095581,0.00023115119,0.00017784159,0.00010585888],"about_ca_topic_score_codex":0.0015326698,"about_ca_topic_score_gemma":0.00033675987,"teacher_disagreement_score":0.08755356,"about_ca_system_score_codex":0.00013777956,"about_ca_system_score_gemma":0.00020402376,"threshold_uncertainty_score":0.41951585},"labels":[],"label_agreement":null},{"id":"W4311144984","doi":"10.1016/j.mimet.2022.106648","title":"Efficiency of CRISPR-Cas9 genetic engineering in Escherichia coli BL21 is impaired by lack of Lon protease","year":2022,"lang":"en","type":"article","venue":"Journal of Microbiological Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"CRISPR; Escherichia coli; Cas9; Protease; Biology; Genome engineering; Computational biology; Protein engineering; Genetics; Gene; Biochemistry; Enzyme","score_opus":0.02153646751490054,"score_gpt":0.3578596033018124,"score_spread":0.33632313578691186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311144984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9063841,0.0046986067,0.08853875,0.00005476837,0.00011219757,0.00016505002,0.000028765264,0.0000027057204,0.00001502499],"genre_scores_gemma":[0.9074652,0.00017543194,0.09220455,0.000061030158,0.00004167635,0.000008129798,0.0000044546605,0.000013956435,0.000025583524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984812,0.00030430403,0.0006979924,0.00019070866,0.000100773235,0.00022499004],"domain_scores_gemma":[0.9992712,0.000062989966,0.00032741416,0.00017990138,0.00008609686,0.00007238055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010896847,0.00015702362,0.0004070926,0.00009572782,0.000023674891,0.0000041705002,0.0003156357,0.00012223316,0.00007523862],"category_scores_gemma":[0.0002877894,0.00013349457,0.00020465482,0.00022719409,0.000054683973,0.0000022640343,0.0001826031,0.00028109032,1.9895786e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014164967,0.00020232014,0.001141823,0.000044390494,0.00004056193,0.0000063654084,0.000075519354,0.0075911735,0.98848516,0.0000018359367,0.00050339167,0.001765806],"study_design_scores_gemma":[0.0007689373,0.0016464051,0.0031941833,0.000021958107,0.000024724008,0.00007243966,0.00008109187,0.0005345651,0.98982745,0.000017777815,0.0036625003,0.00014798695],"about_ca_topic_score_codex":0.000009714046,"about_ca_topic_score_gemma":3.3723938e-7,"teacher_disagreement_score":0.0070566083,"about_ca_system_score_codex":0.000027794971,"about_ca_system_score_gemma":0.000062217274,"threshold_uncertainty_score":0.54437506},"labels":[],"label_agreement":null},{"id":"W4311194927","doi":"10.1158/1538-7445.cancepi22-b002","title":"Abstract B002: A CRISPR/Cas9 screening strategy for identifying modifiers of the viral mimicry response","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Biology; Molecular mimicry; Cell biology; Trans-activating crRNA; Interferon; CRISPR; Genetics; Immune system; Cas9; Gene","score_opus":0.11434967116983762,"score_gpt":0.4658976351301807,"score_spread":0.35154796396034305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311194927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926977,0.0022716557,0.0040035504,0.00025496376,0.0001651978,0.00037282598,0.0001196146,0.0000053065482,0.00010917718],"genre_scores_gemma":[0.9984485,0.00006169605,0.0001815867,0.000036321577,0.00012107934,0.00028773228,0.000013539337,0.000025527655,0.00082400657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987641,0.00013901187,0.00016423105,0.0002604684,0.00032358832,0.00034863193],"domain_scores_gemma":[0.99938023,0.00006424174,0.000040153802,0.00034484948,0.00011734448,0.000053153333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012152907,0.00008479595,0.00009330103,0.00007622609,0.00032982067,0.000024608147,0.00040890064,0.000050654347,0.00006944853],"category_scores_gemma":[0.00013606722,0.00007731589,0.00011461202,0.00017340569,0.00009272151,0.0000029923767,0.0003212696,0.0002739286,4.6246322e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080821844,0.000016776798,0.0001346328,0.00005461445,0.000035555768,0.0000015058937,0.00012876357,0.028081091,0.9648603,0.000023710687,0.0033090862,0.0025457432],"study_design_scores_gemma":[0.0006007768,0.00022251863,0.006858013,0.000024961528,0.000009204038,0.0000050797485,0.0012986095,0.00054540084,0.9699891,0.00008967101,0.020224182,0.00013244072],"about_ca_topic_score_codex":0.00015780391,"about_ca_topic_score_gemma":0.000030747065,"teacher_disagreement_score":0.02753569,"about_ca_system_score_codex":0.000049008795,"about_ca_system_score_gemma":0.00023429774,"threshold_uncertainty_score":0.31528503},"labels":[],"label_agreement":null},{"id":"W4311393649","doi":"10.1089/hum.2022.079","title":"Genome Editing of <i>Pik3cd</i> Impedes Abnormal Retinal Angiogenesis","year":2022,"lang":"fa","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Angiogenesis; Retinal; Biology; Molecular biology; Cell biology; Cancer research; Chemistry; Genetics; Biochemistry","score_opus":0.011974617770479562,"score_gpt":0.28013325002953277,"score_spread":0.26815863225905323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311393649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96029013,0.03694232,0.00084979844,0.00006659711,0.00045812828,0.00029226276,0.00021847601,0.000022914286,0.0008593388],"genre_scores_gemma":[0.9943206,0.002099848,0.00045861205,0.00016698925,0.0015479783,0.00006216608,0.00041843412,0.000093836396,0.0008315565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977962,0.00016187715,0.00055359176,0.0005560455,0.000358389,0.0005739278],"domain_scores_gemma":[0.9988714,0.000013286818,0.00024797,0.0006446704,0.00009407406,0.00012860331],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00050182757,0.00036785365,0.00037141543,0.00012304634,0.0005101737,0.000029113156,0.00054268015,0.00013379332,0.001005006],"category_scores_gemma":[0.000008117789,0.00043451283,0.00037588258,0.00020324411,0.000120032084,0.000004381953,0.00038200995,0.00020368969,0.000005163702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015839672,0.00015625845,0.0018902438,0.000047845973,0.0002530235,0.000018510851,0.00065273116,0.003682776,0.9903134,0.00003284846,0.00039995986,0.0023939852],"study_design_scores_gemma":[0.0014255565,0.0019214267,0.01178149,0.0000110847095,0.000062699786,0.00012449098,0.0006685239,0.00005698664,0.9207507,0.000035824178,0.06259511,0.0005661579],"about_ca_topic_score_codex":0.00005217444,"about_ca_topic_score_gemma":0.000010337408,"teacher_disagreement_score":0.06956276,"about_ca_system_score_codex":0.000044141812,"about_ca_system_score_gemma":0.000096978496,"threshold_uncertainty_score":0.9999082},"labels":[],"label_agreement":null},{"id":"W4311449897","doi":"10.36939/ir.202212141546","title":"It's JustiFlied: The Endogenous Retrovirus K Integrase Induces Motor Disturbances in Transgenic Drosophila","year":2022,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg","funders":"University of Winnipeg","keywords":"Amyotrophic lateral sclerosis; Biology; Integrase; Neurodegeneration; DNA damage; Genome instability; Neuropathology; Genetics; Retrovirus; Transgene; Motor neuron; Gene; Neuroscience; DNA; Disease; Medicine; Pathology","score_opus":0.015067147700719326,"score_gpt":0.29867173925420804,"score_spread":0.2836045915534887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311449897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756871,0.009871141,0.00005630852,0.00014669952,0.0010678421,0.000478643,0.00008403353,0.000020863683,0.012587353],"genre_scores_gemma":[0.9867426,0.0018987543,0.00004656838,0.00019420234,0.00026068368,0.00024475105,0.0017324102,0.000055318877,0.008824678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985791,0.00005604781,0.0003408776,0.0004929122,0.00022584766,0.0003052118],"domain_scores_gemma":[0.99937254,0.00002457767,0.00008362418,0.00043325403,0.00003057304,0.00005540546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001777793,0.00032731527,0.0002476569,0.00009125345,0.00012875324,0.000038088125,0.0004931466,0.00026739677,0.00027873163],"category_scores_gemma":[0.00005373261,0.00025273507,0.00019523066,0.00016405231,0.000034580215,0.000002250283,0.000044569842,0.00046514458,0.0000052989258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003207286,0.000117294374,0.00018022547,0.00017865334,0.00017772311,0.000021800437,0.0018128561,0.00043619366,0.9888285,0.00006481066,0.0020436223,0.005817635],"study_design_scores_gemma":[0.0011403649,0.0008341073,0.007348945,0.00008507271,0.00027289553,0.000046948597,0.013960974,0.000062862884,0.85430163,0.00011903397,0.120436125,0.0013910312],"about_ca_topic_score_codex":0.00022368196,"about_ca_topic_score_gemma":0.0027014175,"teacher_disagreement_score":0.13452682,"about_ca_system_score_codex":0.000034975652,"about_ca_system_score_gemma":0.0001274218,"threshold_uncertainty_score":0.9999925},"labels":[],"label_agreement":null},{"id":"W4311545022","doi":"10.1101/gr.276988.122","title":"Genome sequencing of<i>C. elegans</i>balancer strains reveals previously unappreciated complex genomic rearrangements","year":2022,"lang":"en","type":"article","venue":"Genome Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Children's Hospital Research Institute; Compute Canada; National Institutes of Health; University of Calgary","keywords":"Biology; Caenorhabditis elegans; Genome; CRISPR; Genetics; Cas9; Mutagenesis; Caenorhabditis; Genetic screen; Computational biology; Epistasis; Gene; Mutation; Phenotype","score_opus":0.06587358800998555,"score_gpt":0.3795140408951907,"score_spread":0.31364045288520515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311545022","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99128187,0.0044752597,0.000747046,0.00006147454,0.00007891797,0.00067440537,0.0002229685,0.000019657216,0.0024383795],"genre_scores_gemma":[0.99606884,0.0005674436,0.0007277569,0.00004732732,0.00020486588,0.00013708755,0.00050418393,0.000055059354,0.0016874148],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.997426,0.00032373975,0.0003823304,0.0005170595,0.00058333937,0.00076757383],"domain_scores_gemma":[0.998932,0.000019364985,0.000077447454,0.0006416203,0.00018053465,0.00014899946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018082552,0.00017688336,0.00025391515,0.00020220828,0.00029913487,0.000026910131,0.00063074735,0.000076624245,0.0007465426],"category_scores_gemma":[0.0000555539,0.00020202163,0.0001115792,0.00043783349,0.00010509184,0.0000035881958,0.0007178861,0.00035394906,0.000023588016],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005057151,0.000043503576,0.0007382042,0.00008715738,0.00010712434,0.000009501155,0.00037905492,0.008848662,0.9888521,0.000017703636,0.00037007377,0.00049636635],"study_design_scores_gemma":[0.0045839855,0.0038060995,0.30643553,0.00006609696,0.00010510576,0.00019163973,0.0046321303,0.0011022732,0.18313381,0.0004843092,0.4934749,0.001984123],"about_ca_topic_score_codex":0.00007395407,"about_ca_topic_score_gemma":0.000019163283,"teacher_disagreement_score":0.80571824,"about_ca_system_score_codex":0.00023287638,"about_ca_system_score_gemma":0.0002448457,"threshold_uncertainty_score":0.8238203},"labels":[],"label_agreement":null},{"id":"W4311672203","doi":"10.1038/s41587-022-01591-w","title":"Exploring the value of a global gene drive project registry","year":2022,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Economic and Social Research Council; Biotechnology and Biological Sciences Research Council; National Institutes of Health; Advanced Research Projects Agency; U.S. Department of Agriculture; U.S. Fish and Wildlife Service; Defense Advanced Research Projects Agency","keywords":"Value (mathematics); Gene; Computational biology; Biology; Genetics; Mathematics; Statistics","score_opus":0.01248201245892528,"score_gpt":0.28174390127864646,"score_spread":0.2692618888197212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311672203","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2615744,0.04013884,0.0036687786,0.68154985,0.0071654385,0.002104254,0.0015641635,0.0003729448,0.0018613723],"genre_scores_gemma":[0.63570875,0.011608436,0.01039801,0.3176557,0.015138466,0.0014776594,0.004352048,0.0004885725,0.0031723112],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99837935,0.00006440439,0.00026768568,0.0006353891,0.0002537493,0.00039943407],"domain_scores_gemma":[0.99848396,0.000018935461,0.0001782092,0.0012513316,0.000051447125,0.000016149048],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00013174534,0.00032957527,0.00031606105,0.000083684834,0.00008846893,0.000010177803,0.0010389324,0.0027436835,0.000011284227],"category_scores_gemma":[0.00015664347,0.00026959548,0.00022053884,0.00036127446,0.00020963537,0.0000016260036,0.0006672132,0.0031146484,0.0000016206274],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060195485,0.00002864052,0.00007053206,0.00017215249,0.00039961853,0.00015658708,0.000026422409,0.00014363261,0.17021213,0.00076931575,0.824938,0.0030227683],"study_design_scores_gemma":[0.00013964395,0.0002098135,0.00007039227,0.000013167772,0.000049962553,0.00019157652,0.0000392546,0.0000075913426,0.2083001,0.00005284525,0.7906983,0.00022734707],"about_ca_topic_score_codex":0.000044598066,"about_ca_topic_score_gemma":0.000012100232,"teacher_disagreement_score":0.3741344,"about_ca_system_score_codex":0.000060307862,"about_ca_system_score_gemma":0.00017064586,"threshold_uncertainty_score":0.9999756},"labels":[],"label_agreement":null},{"id":"W4311946762","doi":"10.3389/fbioe.2022.1103007","title":"Editorial: Current approaches to CRISPR/Cas9 delivery","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Genome editing; Gene delivery; Computational biology; Cas9; Current (fluid); Genetic enhancement; Biology; Gene; Genetics; Physics","score_opus":0.011223496594781225,"score_gpt":0.24711728829402063,"score_spread":0.2358937916992394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311946762","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013078764,0.02065475,0.032204673,0.00017346197,0.9450256,0.00032778436,0.00017342479,0.000113912254,0.000018487088],"genre_scores_gemma":[0.002384029,0.011559906,0.008255637,0.000014571412,0.9765323,0.00023300953,0.000691967,0.00013875135,0.00018986987],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977624,0.0000315789,0.0003608974,0.0009465631,0.00030857912,0.00059001957],"domain_scores_gemma":[0.9991651,0.000023346422,0.00006713719,0.0005822174,0.000032923566,0.00012925727],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00029373405,0.00048856094,0.00051179796,0.0006464915,0.00007537287,0.00003693927,0.00054196327,0.0016149572,0.000004220304],"category_scores_gemma":[0.0002715999,0.0005512846,0.00010411336,0.0003495629,0.00008554698,0.0000035577857,0.0007090811,0.0012522315,0.0000020123223],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054279248,0.000036026424,0.000051656927,0.00015169097,0.00006273594,0.000004609046,0.000025701558,0.0019910194,0.003918223,0.000012509795,0.9814724,0.012219151],"study_design_scores_gemma":[0.0003842572,0.00030915719,0.000009051533,0.000049595892,0.000030264946,0.0000041640074,0.00008971223,0.00041329412,0.00613678,0.00001842871,0.9919517,0.0006035843],"about_ca_topic_score_codex":0.00002527013,"about_ca_topic_score_gemma":0.000012572175,"teacher_disagreement_score":0.031506628,"about_ca_system_score_codex":0.00009350203,"about_ca_system_score_gemma":0.00010125435,"threshold_uncertainty_score":0.9996939},"labels":[],"label_agreement":null},{"id":"W4312112810","doi":"10.1101/2022.12.21.521522","title":"CRISPR prime editing for unconstrained correction of oncogenic <i>KRAS</i> variants","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Foundation of Korea; National Research Foundation; Public Health Agency of Canada","keywords":"KRAS; CRISPR; Cancer research; Mutation; Oncogene; Biology; Genetics; Computational biology; Cancer; Gene; Cell cycle","score_opus":0.008615491881392608,"score_gpt":0.25460167896896146,"score_spread":0.24598618708756886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312112810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8483855,0.0025341697,0.1371221,0.00008015025,0.008999883,0.0016028318,0.0010395098,0.0001719821,0.00006383325],"genre_scores_gemma":[0.9909482,0.00015439482,0.007080237,0.00007569546,0.0012319728,0.00033937502,0.000008710248,0.00013289372,0.000028540988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779147,0.00006873044,0.0005693119,0.00086583686,0.00025124874,0.00045342324],"domain_scores_gemma":[0.99814606,0.000036520967,0.00041155663,0.0009102954,0.00034820076,0.00014734706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005768561,0.00043190716,0.0004581306,0.00013964046,0.00014248771,0.00004523798,0.00043817007,0.0004460236,0.00004566547],"category_scores_gemma":[0.00036880243,0.00053293887,0.00029419502,0.00020369214,0.00007184698,0.00000567078,0.0005062338,0.0004001428,0.0000021000012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056328245,0.00008412908,0.0006575725,0.00026632473,0.00021017189,0.0000037115801,0.0000061772566,0.0022242246,0.99523705,0.000028795008,0.0012101983,0.000015288293],"study_design_scores_gemma":[0.00063803705,0.00020452734,0.0033815948,0.000102477265,0.00015031744,6.142978e-8,0.000012200665,0.0010789945,0.9775495,9.601364e-7,0.01635209,0.0005292502],"about_ca_topic_score_codex":0.000027774147,"about_ca_topic_score_gemma":0.0000027636781,"teacher_disagreement_score":0.14256264,"about_ca_system_score_codex":0.00009471636,"about_ca_system_score_gemma":0.00054006255,"threshold_uncertainty_score":0.9997122},"labels":[],"label_agreement":null},{"id":"W4312114042","doi":"10.1038/s41592-022-01705-x","title":"Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq","year":2022,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Defense Advanced Research Projects Agency; National Human Genome Research Institute; York University; National Cancer Institute; National Institutes of Health; Cancer Research Institute","keywords":"RNA-Seq; RNA; Computational biology; Biology; Gene expression; Genetics; Transcriptome; Gene","score_opus":0.00695308687565568,"score_gpt":0.31377739885457334,"score_spread":0.3068243119789177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312114042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9557522,0.006119645,0.035002593,0.00006579401,0.0015919363,0.0002177781,0.000021841868,0.000012589907,0.001215655],"genre_scores_gemma":[0.94933915,0.000010675672,0.05031878,0.00006681067,0.00012433167,0.00001645753,0.000023074403,0.000025754356,0.000074936805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988565,0.00022606087,0.00020411266,0.00029109407,0.00019585068,0.00022639628],"domain_scores_gemma":[0.99958855,0.000042443702,0.00005690542,0.00021623554,0.000047981244,0.000047897778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068394875,0.00014554888,0.0001978554,0.00007214595,0.0000591311,0.00000639549,0.00018130339,0.00016670067,0.00002248681],"category_scores_gemma":[0.000078749115,0.00013459787,0.00007821219,0.00022594557,0.000038506325,8.3102543e-7,0.000078229335,0.00046237282,1.2767936e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012871469,0.00011624925,0.000054734737,0.00003023403,0.000020841127,0.000007305752,0.00033014288,0.03855837,0.9584254,0.000069777474,0.000192593,0.0020656395],"study_design_scores_gemma":[0.0008981673,0.00041676903,0.00013415734,0.000009504583,0.000017844523,0.000009030677,0.00025664177,0.0014128102,0.98311955,0.000033605993,0.013510372,0.0001815199],"about_ca_topic_score_codex":0.000020853822,"about_ca_topic_score_gemma":0.000005431226,"teacher_disagreement_score":0.037145562,"about_ca_system_score_codex":0.000031362753,"about_ca_system_score_gemma":0.000045276956,"threshold_uncertainty_score":0.54887414},"labels":[],"label_agreement":null},{"id":"W4312210296","doi":"10.1016/j.xpro.2022.101933","title":"An efficient and cost-effective purification protocol for Staphylococcus aureus Cas9 nuclease","year":2022,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Ted Rogers Centre for Heart Research; University of Toronto","funders":"University of Toronto","keywords":"CRISPR; Nuclease; Cas9; Staphylococcus aureus; Chemistry; Chromatography; Palindrome; Computational biology; Biology; Bacteria; DNA; Biochemistry; Genetics; Gene","score_opus":0.016635997734750656,"score_gpt":0.3804183217032048,"score_spread":0.3637823239684541,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312210296","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03992851,0.0000077303,0.014475361,0.000032845488,0.000021320693,0.94528204,0.00014438193,0.000028599052,0.000079231926],"genre_scores_gemma":[0.101854295,9.563444e-8,0.0015015407,0.000054429725,0.0000976941,0.8963515,0.000060332455,0.000029387147,0.00005068994],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990114,0.000079870515,0.00015989099,0.00039404837,0.00012691542,0.0002278476],"domain_scores_gemma":[0.9993984,0.00001095187,0.00006449508,0.00035485308,0.000068631074,0.000102664824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029994894,0.00014513935,0.000108208944,0.000041012347,0.00023041318,0.000035374884,0.00015079348,0.00005139338,0.000033732587],"category_scores_gemma":[0.00003290351,0.00014862852,0.00004866462,0.00006822143,0.000034307563,0.0000026979767,0.00009175173,0.0000877452,9.899978e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001197164,0.00043581115,0.00032155844,0.00025122447,0.00003447023,0.0000028776508,0.00027413754,0.015227395,0.9599959,0.00020583477,0.0015572046,0.020496389],"study_design_scores_gemma":[0.0035255416,0.0033900524,0.0020310536,0.000015912598,0.000010722385,0.0000063923026,0.00022496599,0.007952838,0.36110973,0.00007325241,0.62130916,0.0003503739],"about_ca_topic_score_codex":0.0000078953735,"about_ca_topic_score_gemma":0.000005585464,"teacher_disagreement_score":0.619752,"about_ca_system_score_codex":0.000033995006,"about_ca_system_score_gemma":0.00005627628,"threshold_uncertainty_score":0.6060895},"labels":[],"label_agreement":null},{"id":"W4312383238","doi":"10.1016/bs.fp.2022.04.008","title":"Applied aspects of gene function for the conservation of fishes","year":2022,"lang":"en","type":"book-chapter","venue":"Fish physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Biology; Gene; Gene expression; Function (biology); Evolutionary biology; Abiotic component; Stressor; Phenotype; Regulation of gene expression; Genetics; Computational biology; Ecology; Neuroscience","score_opus":0.011683190564616973,"score_gpt":0.23859937541124918,"score_spread":0.2269161848466322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312383238","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13014498,0.014190132,0.07661773,0.002042077,0.0077213366,0.009131059,0.0055006216,0.00014254774,0.7545095],"genre_scores_gemma":[0.97301304,0.0009554345,0.00047450038,0.0007975771,0.0009581932,0.00022617514,0.0040246793,0.000099522615,0.019450901],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994331,0.00000597864,0.00020192444,0.00020738707,0.000059713435,0.00009189868],"domain_scores_gemma":[0.9994117,0.000045306817,0.00017401858,0.00029166922,0.000065237815,0.000012071344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006113483,0.00012803743,0.00021122511,0.000025772422,0.000037098245,0.0000012767476,0.00013297037,0.00016747895,0.00014140377],"category_scores_gemma":[0.000015846112,0.00011293605,0.00012520899,0.000012896764,0.00006932257,6.046055e-7,0.0000645321,0.000077347424,5.653271e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002277909,0.000013091148,0.0000033197418,0.00012801813,0.00024149322,7.8160504e-8,0.00001714981,0.0011328593,0.9735869,0.015374166,0.007916637,0.0013585064],"study_design_scores_gemma":[0.0005017428,0.0006930219,0.0027211274,0.00001121754,0.00016498838,0.0000025183058,0.000019995188,0.000088778135,0.24333207,0.0051629627,0.7470829,0.00021870021],"about_ca_topic_score_codex":0.0000069844646,"about_ca_topic_score_gemma":0.000014598069,"teacher_disagreement_score":0.84286803,"about_ca_system_score_codex":0.00000582764,"about_ca_system_score_gemma":0.0000417225,"threshold_uncertainty_score":0.46053985},"labels":[],"label_agreement":null},{"id":"W4312747281","doi":"10.1007/978-3-031-08072-2_14","title":"Applications of Gene Drive for Weeds and Pest Management Using CRISPR/Cas9 System in Plants","year":2022,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Agriculture; Integrated pest management; Biotechnology; Genome editing; Gene drive; Crop; Resistance (ecology); Cas9; Crop protection; Agronomy; Agroforestry; Gene; Ecology; Genetics","score_opus":0.010192498275881331,"score_gpt":0.27233372544357587,"score_spread":0.26214122716769456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312747281","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009055576,0.01095567,0.6404211,0.000030799692,0.00034382934,0.0042237514,0.0010035938,0.00004298889,0.33392268],"genre_scores_gemma":[0.7801528,0.003748041,0.049275573,0.000097668206,0.000605787,0.00089320017,0.0020164961,0.0002734647,0.16293699],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99931276,0.000003309815,0.00021675936,0.00027971948,0.00007407145,0.00011339208],"domain_scores_gemma":[0.99963963,0.0000066133216,0.00006818341,0.00023187419,0.000021623504,0.000032071523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007000541,0.00014996105,0.00018205096,0.00010101567,0.000034142227,0.000005525137,0.00009656846,0.000116454255,0.00001897254],"category_scores_gemma":[8.3617647e-7,0.00016500961,0.00005718805,0.0000133657295,0.000019584937,7.3328357e-7,0.000115863426,0.000053360694,4.4314982e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045001844,0.00025811844,0.0006626725,0.012539578,0.0026463028,0.00007703565,0.00046237878,0.016045809,0.55608183,0.3360959,0.003319915,0.071360424],"study_design_scores_gemma":[0.0015158001,0.00030999648,0.00015794788,0.0002329573,0.00030568358,0.000102778606,0.00090419926,0.0021566814,0.06691826,0.0003134006,0.9261454,0.0009368908],"about_ca_topic_score_codex":0.000017167393,"about_ca_topic_score_gemma":0.000019111889,"teacher_disagreement_score":0.9228255,"about_ca_system_score_codex":0.000025383064,"about_ca_system_score_gemma":0.000014972746,"threshold_uncertainty_score":0.67288965},"labels":[],"label_agreement":null},{"id":"W4312919370","doi":"10.47611/jsr.v11i1.1534","title":"Current Sickle Cell Disease Gene Therapy Treatments: Literature Review","year":2022,"lang":"en","type":"article","venue":"Journal of Student Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"Genetic enhancement; CRISPR; Genome editing; Disease; Viral vector; Fetal hemoglobin; Cas9; Medicine; Gene; Haematopoiesis; Stem cell; Clinical trial; Bioinformatics; Mutation; Immunology; Biology; Fetus; Internal medicine; Genetics; Pregnancy; Recombinant DNA","score_opus":0.04990678952834119,"score_gpt":0.4636350668056981,"score_spread":0.4137282772773569,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312919370","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40371326,0.5953719,0.00007530492,0.00035267073,0.0001811502,0.00020419837,0.0000148607905,0.0000014771234,0.000085194864],"genre_scores_gemma":[0.536848,0.4619311,0.00006857406,0.00011038423,0.00038058392,0.000037511905,0.000031689364,0.000015073591,0.0005770738],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99843293,0.00019309661,0.00023905032,0.00015396722,0.0007575824,0.00022338094],"domain_scores_gemma":[0.9992635,0.000013185401,0.00007053553,0.0002396197,0.00024882573,0.00016433271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007774914,0.000097265256,0.00013960966,0.00009525456,0.00014045283,0.000033454293,0.00037428908,0.000017113496,0.00009284534],"category_scores_gemma":[0.00002233408,0.00007548064,0.00015600267,0.00021335557,0.000020373735,0.0000032846694,0.00024261633,0.000378881,0.0000027175593],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091721193,0.004803164,0.020822546,0.0011852083,0.0005779921,0.0008055631,0.0008709247,0.0019815376,0.7421685,0.000022054586,0.16438167,0.061463643],"study_design_scores_gemma":[0.0025471994,0.0028607706,0.029478358,0.00061141304,0.00006797358,0.00013387915,0.0002247692,0.000012033544,0.054653574,0.000042699936,0.9090818,0.00028552307],"about_ca_topic_score_codex":5.7865805e-7,"about_ca_topic_score_gemma":1.7410864e-7,"teacher_disagreement_score":0.74470013,"about_ca_system_score_codex":0.000052589236,"about_ca_system_score_gemma":0.00012380481,"threshold_uncertainty_score":0.3078011},"labels":[],"label_agreement":null},{"id":"W4313168632","doi":"10.2139/ssrn.4292602","title":"R-Loop Editing by DNA Cytosine Deaminase APOBEC3B Determines the Activity of Estrogen Receptor Enhancers","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Cytidine deaminase; Enhancer; Genome instability; Biology; Estrogen receptor; DNA damage; Epigenetics; Cytosine deaminase; DNA; Estrogen receptor alpha; Cytosine; Molecular biology; Cell biology; Genetics; Gene; Cancer; Breast cancer; Gene expression","score_opus":0.0033984672191015395,"score_gpt":0.24851080275448803,"score_spread":0.2451123355353865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313168632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98514307,0.005906309,0.008241222,0.0002558906,0.0002825222,0.000091497415,0.000020114188,0.0000061538667,0.000053233278],"genre_scores_gemma":[0.9974491,0.0012438755,0.00005965121,0.000037002163,0.00049504056,0.000018831503,0.000021016118,0.000024061252,0.00065143773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853224,0.00008340273,0.00018105381,0.00017622729,0.00019051647,0.00083655166],"domain_scores_gemma":[0.99956226,0.000016587768,0.00014302174,0.00019031977,0.000041236344,0.000046568588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069387635,0.0001321871,0.00012444504,0.000030048019,0.00025797446,0.000013001814,0.00029308317,0.00004184097,0.00003074071],"category_scores_gemma":[0.000055362532,0.000111974055,0.00012001791,0.00009985888,0.000042764306,0.0000044054627,0.00012263242,0.0006033904,8.9149654e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006229101,0.000038632574,0.00020340017,0.000005236597,0.00009113856,5.5005563e-7,0.00003158124,0.00044004084,0.98269993,0.00006983558,0.00075108313,0.015606279],"study_design_scores_gemma":[0.00042067142,0.00065465574,0.00005386582,0.0000048087795,0.000035792862,0.00023260912,0.0007673708,0.00014042815,0.9824535,0.00018317442,0.014900975,0.00015213627],"about_ca_topic_score_codex":0.000027735641,"about_ca_topic_score_gemma":0.00005179239,"teacher_disagreement_score":0.015454142,"about_ca_system_score_codex":0.00013913384,"about_ca_system_score_gemma":0.00042463257,"threshold_uncertainty_score":0.45661694},"labels":[],"label_agreement":null},{"id":"W4313260498","doi":"10.3390/fermentation9010014","title":"A Toolkit for Effective and Successive Genome Engineering of Escherichia coli","year":2022,"lang":"en","type":"article","venue":"Fermentation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Recombineering; CRISPR; Genome engineering; Transposable element; Biology; Genome editing; Plasmid; Transposon mutagenesis; Genome; Cas9; Genetics; Escherichia coli; Gene; Computational biology","score_opus":0.003693109218057356,"score_gpt":0.2665740619006481,"score_spread":0.2628809526825907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313260498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95065916,0.0002453526,0.048653148,0.000012770975,0.000065444445,0.00030872214,0.000030601514,0.000003890733,0.000020931671],"genre_scores_gemma":[0.99815834,0.000010325569,0.001357148,0.000021692322,0.00003595434,0.00024355073,0.00011632117,0.000008585396,0.000048061065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997255,0.000008401276,0.00006622295,0.00009761011,0.000039104223,0.00006314832],"domain_scores_gemma":[0.99988484,0.000009325758,0.000026202026,0.00004771778,0.000016647204,0.000015238103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053395357,0.000045846562,0.00005060806,0.000020540609,0.000036704405,0.000004125412,0.00003056607,0.000014820478,0.0000070779884],"category_scores_gemma":[0.000017112725,0.000053923475,0.00002046996,0.000035183595,0.000006077941,0.0000015021835,0.0000392747,0.000020959822,8.704731e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004662247,0.000010109396,0.00036608044,0.000035486,0.000022348268,1.4540171e-7,0.00017212765,0.011573491,0.9870849,0.000043422588,0.000018617335,0.00062661513],"study_design_scores_gemma":[0.0011778063,0.0007991501,0.0833754,0.0000047252524,0.000032908458,0.0000034642078,0.0004174598,0.0047383215,0.9061185,0.00002968806,0.0031388307,0.00016371091],"about_ca_topic_score_codex":0.0000038397866,"about_ca_topic_score_gemma":7.735454e-7,"teacher_disagreement_score":0.083009325,"about_ca_system_score_codex":0.000011119425,"about_ca_system_score_gemma":0.000008002084,"threshold_uncertainty_score":0.21989354},"labels":[],"label_agreement":null},{"id":"W4313437327","doi":"10.1002/ajmg.c.32028","title":"Data sharing to advance gene‐targeted therapies in rare diseases","year":2023,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part C Seminars in Medical Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Impact","funders":"","keywords":"Data sharing; Harmonization; Translational research; Globe; Standardization; Medicine; Data science; Ethical issues; Scale (ratio); Computer science; Engineering ethics; Alternative medicine; Engineering; Geography; Pathology","score_opus":0.01660401030378926,"score_gpt":0.3594041883646288,"score_spread":0.3428001780608395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313437327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96528554,0.024075847,0.0069477307,0.0025304835,0.00082399364,0.00020667374,0.000081762926,0.000019549041,0.000028403645],"genre_scores_gemma":[0.89694655,0.09077812,0.008932961,0.0017456124,0.0011876944,0.000024123474,0.0002142493,0.00010021385,0.000070474394],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948897,0.0001846165,0.0012442251,0.0007406478,0.0021260702,0.00081474567],"domain_scores_gemma":[0.9971168,0.00018769808,0.0002451128,0.001113677,0.00012555173,0.0012111486],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021903976,0.00035096725,0.0006540881,0.0003904127,0.000047777798,0.000035492714,0.002975368,0.00028310134,0.00012178458],"category_scores_gemma":[0.0027349459,0.00033410688,0.00011945833,0.001215707,0.00041512641,0.000008059569,0.0014661156,0.0006379576,0.000013921427],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038728383,0.00052530796,0.17526697,0.000117593954,0.00024693104,0.0020687713,0.0011270494,0.024260897,0.021674164,0.000011518785,0.01954074,0.7547728],"study_design_scores_gemma":[0.008805368,0.0068308217,0.19991943,0.0044452497,0.00025989825,0.0015274524,0.008113262,0.07499562,0.041072864,0.00056459033,0.650059,0.0034064485],"about_ca_topic_score_codex":0.000011096957,"about_ca_topic_score_gemma":0.00013215786,"teacher_disagreement_score":0.7513663,"about_ca_system_score_codex":0.000041223295,"about_ca_system_score_gemma":0.0005463714,"threshold_uncertainty_score":0.99991107},"labels":[],"label_agreement":null},{"id":"W4313445110","doi":"10.1007/978-1-0716-2914-7_24","title":"A CRISPR Platform for Targeted In Vivo Screens","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CRISPR; Computational biology; Tumor microenvironment; Genome editing; In vivo; Genetic screen; In silico; Function (biology); Cancer; Biology; Bioinformatics; Computer science; Phenotype; Genetics; Gene","score_opus":0.02413438058395476,"score_gpt":0.44125969661955833,"score_spread":0.41712531603560354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313445110","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12326939,0.00076839386,0.8748113,0.000117998665,0.00023958729,0.00036885223,0.000030588944,0.000031009702,0.00036289112],"genre_scores_gemma":[0.14174326,0.00022275842,0.85642475,0.0004308336,0.00013478842,0.00035826612,0.0002352642,0.00007195242,0.00037810806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853164,0.00015228771,0.00030568952,0.00046298275,0.000043976772,0.0005034455],"domain_scores_gemma":[0.9994604,0.00007914451,0.00003814799,0.0003327886,0.000032726344,0.00005678694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010021833,0.00018521829,0.0002537322,0.0002682856,0.000025520863,0.0000074658547,0.0002220815,0.00030963094,0.000014393046],"category_scores_gemma":[0.00055625517,0.00019244388,0.00011481473,0.000400605,0.000054331005,0.0000015417068,0.00014109795,0.00012290035,0.0000036452702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049953873,0.000018774288,0.0011308935,0.000021036694,0.000020906888,0.000010704635,0.000038403123,0.0015485202,0.98983747,0.0005827368,0.00031310553,0.0064275004],"study_design_scores_gemma":[0.0008551847,0.00022012473,0.00087378337,0.000010387679,0.0000066944467,0.0000065557024,0.000075734955,0.0026333886,0.959477,0.0025727053,0.033016942,0.00025148678],"about_ca_topic_score_codex":0.00003348169,"about_ca_topic_score_gemma":0.000087139975,"teacher_disagreement_score":0.032703836,"about_ca_system_score_codex":0.000017227665,"about_ca_system_score_gemma":0.00003649978,"threshold_uncertainty_score":0.7847634},"labels":[],"label_agreement":null},{"id":"W4313454447","doi":"10.1038/s41587-022-01516-7","title":"CRISPR-edited plants by grafting","year":2023,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Grafting; Biology; Computational biology; Chemistry; Genetics; Gene","score_opus":0.0036941961794525677,"score_gpt":0.2829332200758302,"score_spread":0.27923902389637767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313454447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853264,0.0051844935,0.0042451825,0.0027554121,0.0010067542,0.00017289202,0.00009003902,0.00055082806,0.00066801603],"genre_scores_gemma":[0.99691474,0.0007772555,0.00042515478,0.000301814,0.00023558155,0.000013593676,0.00039022492,0.000030661766,0.00091099454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990516,0.000011276954,0.00012899343,0.00036650486,0.000093073075,0.0003485867],"domain_scores_gemma":[0.9995394,0.000010886961,0.000031712545,0.00034929402,0.000022364477,0.0000463375],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001032807,0.00014746592,0.000119044686,0.00013793833,0.00006111393,0.000009569394,0.00025624837,0.001353183,0.00000970493],"category_scores_gemma":[0.00014536899,0.00014604905,0.000051243012,0.00029058245,0.000055922734,0.0000012704961,0.00016282768,0.00044832798,0.00005518345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010131845,0.000008843256,0.00016526632,0.0000072834578,0.00002537715,0.000008128865,0.000006000284,0.000023583929,0.895646,0.000113221024,0.09925411,0.0047321026],"study_design_scores_gemma":[0.00018920818,0.00006205383,0.00032173906,0.000004533633,0.0000037987907,0.000019174964,0.00003312158,0.000121920864,0.68172985,0.000045990153,0.317339,0.00012960874],"about_ca_topic_score_codex":0.00000401516,"about_ca_topic_score_gemma":0.000007709848,"teacher_disagreement_score":0.21808489,"about_ca_system_score_codex":0.000006787879,"about_ca_system_score_gemma":0.000013599685,"threshold_uncertainty_score":0.99994326},"labels":[],"label_agreement":null},{"id":"W4313534596","doi":"10.5281/zenodo.7504499","title":"Synergistic inter-clonal cooperation involving crosstalk, co-option and co-dependency can enhance the invasiveness of genetically distant cancer clones Dataset","year":2023,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Crosstalk; Genetically engineered; Dependency (UML); Computational biology; Biology; Computer science; Genetics; Gene; Engineering; Artificial intelligence","score_opus":0.0230960687731391,"score_gpt":0.32340083955440413,"score_spread":0.30030477078126505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313534596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97420573,0.0005162485,0.021352017,0.0003202777,0.00009086283,0.00032025663,0.0026343788,0.00007459358,0.00048560544],"genre_scores_gemma":[0.9896498,0.00096970954,0.000037416557,0.000038939223,0.00008161878,2.750326e-7,0.008925148,0.00018535323,0.0001117804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991332,0.000101714555,0.00017723702,0.00026359365,0.00014707506,0.00017712242],"domain_scores_gemma":[0.99942607,0.000014915446,0.00005307742,0.00025598324,0.00018618545,0.00006376594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029585973,0.000095029325,0.00008390397,0.000052527746,0.0005360678,0.00016152588,0.0002981057,0.000046006724,0.0003035351],"category_scores_gemma":[0.00024621453,0.00008507214,0.000019151523,0.00015711911,0.00016679634,0.000008927265,0.0003558771,0.00008350667,0.00005412662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005144272,0.00002475283,0.000058326692,0.00009551263,0.0000353378,0.0000038135663,0.00028101422,0.00094373216,0.97633517,0.00040737065,0.011644339,0.010119199],"study_design_scores_gemma":[0.00058629806,0.00041617567,0.006722995,0.00008897419,0.00003778427,0.000045238266,0.00048307466,0.0028922819,0.56500304,0.0000973863,0.42327774,0.00034904023],"about_ca_topic_score_codex":0.000041845597,"about_ca_topic_score_gemma":0.000016030697,"teacher_disagreement_score":0.41163337,"about_ca_system_score_codex":0.0000206025,"about_ca_system_score_gemma":0.000008857146,"threshold_uncertainty_score":0.4123054},"labels":[],"label_agreement":null},{"id":"W4313907616","doi":"10.1021/acs.analchem.2c04555","title":"Signal Amplification by the <i>trans</i>-Cleavage Activity of CRISPR-Cas Systems: Kinetics and Performance","year":2023,"lang":"en","type":"review","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Web of science; Library science; Biological sciences; Medicine; Internal medicine; Computer science; Biology; Computational biology","score_opus":0.02786673265109597,"score_gpt":0.33536351972689954,"score_spread":0.3074967870758036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313907616","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018223922,0.9878273,0.009104898,0.00002038764,0.000048591784,0.00027727726,0.000165022,0.000019947352,0.0007141773],"genre_scores_gemma":[0.08980367,0.90872157,0.000011365795,0.000005698992,0.00018402404,0.000036331967,0.00021725858,0.000047289057,0.0009727789],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99878526,0.000032181684,0.0003834105,0.0003910582,0.00017655674,0.00023152545],"domain_scores_gemma":[0.9991797,0.00006978542,0.00014468093,0.00046674017,0.000047059417,0.000092013666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018036416,0.0002908161,0.0005662854,0.000017185099,0.000043567532,0.000030204485,0.0002719345,0.0003696295,0.0000073917295],"category_scores_gemma":[0.00004764692,0.0002206225,0.00018891215,0.00015456391,0.00014771534,0.0000020301202,0.00009765029,0.00025824292,0.0000032783842],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007430358,0.0003616519,0.000081384555,0.1523913,0.0019120517,0.000008545209,0.00005735505,0.00024292213,0.34509405,0.000019431407,0.034071475,0.46568552],"study_design_scores_gemma":[0.0001507521,0.00009762112,0.000023671335,0.001465008,0.00087427284,0.00005549701,0.000021507418,0.0010294697,0.17827101,0.000001135618,0.8175423,0.00046774218],"about_ca_topic_score_codex":0.00000828483,"about_ca_topic_score_gemma":4.4626017e-7,"teacher_disagreement_score":0.7834708,"about_ca_system_score_codex":0.00001795074,"about_ca_system_score_gemma":0.00005062066,"threshold_uncertainty_score":0.89967245},"labels":[],"label_agreement":null},{"id":"W4315645017","doi":"10.1038/s41396-023-01358-4","title":"CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice","year":2023,"lang":"en","type":"article","venue":"The ISME Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Danish Agency for Science and Higher Education; Canadian Institutes of Health Research; Danmarks Frie Forskningsfond; Ministeriet for Forskning Innovation og Videregående Uddannelser; Canada Research Chairs","keywords":"Biology; Microbiology; Bacteria; Immunity; CRISPR; Virology; Phage therapy; Bacteriophage; Immunology; Immune system; Escherichia coli; Genetics","score_opus":0.014274829616702612,"score_gpt":0.31281772679256836,"score_spread":0.29854289717586574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315645017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941723,0.00055329065,0.003056838,0.0015402484,0.0002980243,0.00022626726,0.000006779143,0.00001782581,0.00012847387],"genre_scores_gemma":[0.9978933,0.00034219402,0.00025553108,0.0002845806,0.00032452922,0.000012815475,0.000010332435,0.000023143255,0.00085359666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904156,0.00011914449,0.00023917189,0.00015159082,0.00012769885,0.00032085995],"domain_scores_gemma":[0.99948454,0.000030334706,0.00004930515,0.00028506664,0.00005044986,0.00010028472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068711827,0.00013504548,0.000120789664,0.000099150195,0.00010585081,0.00006035482,0.00033156533,0.0000703688,0.000029281971],"category_scores_gemma":[0.00017625296,0.000101717524,0.000082107494,0.00023175486,0.000023913188,0.0000042556508,0.00017907356,0.00025932328,0.00004802965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051695988,0.000033691136,0.00064895774,0.00002519827,0.00003286457,0.000015515418,0.0005768546,0.0027255807,0.99026424,0.000001847019,0.0032939415,0.0023296007],"study_design_scores_gemma":[0.0011019879,0.00051490654,0.244156,0.00014912576,0.000057526497,0.00043225905,0.00095159066,0.0018149597,0.7204801,0.00010005191,0.029793644,0.00044789122],"about_ca_topic_score_codex":0.000022177126,"about_ca_topic_score_gemma":0.00003998075,"teacher_disagreement_score":0.26978418,"about_ca_system_score_codex":0.000026957558,"about_ca_system_score_gemma":0.000048784907,"threshold_uncertainty_score":0.41479203},"labels":[],"label_agreement":null},{"id":"W4315782305","doi":"10.3389/fbioe.2022.1110376","title":"Biofoundries and citizen science can accelerate disease surveillance and environmental monitoring","year":2023,"lang":"en","type":"article","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biosecurity; Scope (computer science); Citizen science; Business; Product (mathematics); Political science; Public relations; Computer science; Medicine","score_opus":0.004681125450163103,"score_gpt":0.23196747441563845,"score_spread":0.22728634896547534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315782305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99189216,0.005510115,0.0017852249,0.0003387281,0.00030369498,0.000078637386,0.000022119324,0.00006454469,0.0000047637623],"genre_scores_gemma":[0.9887496,0.009543424,0.0015689614,0.000009156779,0.000044134704,0.000010286439,0.000014422283,0.000013820344,0.000046179066],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991886,0.0000051662637,0.0000984504,0.000355272,0.00005837787,0.00029415163],"domain_scores_gemma":[0.9997324,0.00000438095,0.000014275081,0.00015194496,0.0000043275386,0.00009269885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120026976,0.00013312521,0.000118527525,0.00025347908,0.000081846854,0.000032962682,0.00009620775,0.00011813027,2.2820946e-7],"category_scores_gemma":[0.00003720197,0.00013918034,0.0000107155165,0.0002264885,0.00040988708,0.000005219091,0.00021361776,0.000093339986,2.0211677e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018041195,0.000006261622,0.285062,0.000049724644,0.000016068445,0.000014563516,0.000053601005,0.00039575138,0.6992931,0.000059752554,0.000065502645,0.014965646],"study_design_scores_gemma":[0.00088273507,0.00019640544,0.57658374,0.00006252589,0.000013278633,0.000052326814,0.0010480819,0.017115807,0.39690846,0.00023447824,0.0061708842,0.00073129265],"about_ca_topic_score_codex":0.000007426811,"about_ca_topic_score_gemma":0.000002938751,"teacher_disagreement_score":0.30238464,"about_ca_system_score_codex":0.000012937347,"about_ca_system_score_gemma":0.000012204417,"threshold_uncertainty_score":0.5675609},"labels":[],"label_agreement":null},{"id":"W4317390629","doi":"10.1101/2023.01.17.23284659","title":"Specimen sharing for epidemic preparedness: building a local-to-global virtual biorepository framework","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Canadian Institutes of Health Research; European Commission","keywords":"Biorepository; Preparedness; General partnership; Corporate governance; Business; Knowledge management; Computer science; Political science; Biobank","score_opus":0.024464762542660716,"score_gpt":0.35829726760379565,"score_spread":0.33383250506113493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317390629","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4758186,0.000593122,0.5208424,0.000082796425,0.001912058,0.00048413672,0.00009777177,0.00009253478,0.00007659065],"genre_scores_gemma":[0.9771349,0.00010367896,0.019387709,0.00014499303,0.0019933272,0.00041708734,0.00015749875,0.00011710446,0.0005437294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99743557,0.000030489226,0.00049099553,0.0012751708,0.00020290111,0.0005649006],"domain_scores_gemma":[0.99839926,0.000057441877,0.0001244488,0.0010839703,0.00009659493,0.00023829949],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047076307,0.00042870073,0.0004173563,0.00008655713,0.00009328212,0.000072860115,0.0008046315,0.0006558938,0.0000067117385],"category_scores_gemma":[0.00051617454,0.00047538397,0.0003070884,0.00014933843,0.000055505105,0.0000020119605,0.0017318737,0.0003113722,0.000023975945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000411983,0.00012810684,0.040839754,0.0010145832,0.001046169,0.000049866194,0.000745966,0.455191,0.47857672,0.0014200296,0.012103642,0.008472201],"study_design_scores_gemma":[0.002317723,0.0018845989,0.035783943,0.0043589375,0.0008568464,0.00010631601,0.0013294943,0.047455166,0.7707592,0.024910618,0.10343455,0.006802597],"about_ca_topic_score_codex":0.000042165575,"about_ca_topic_score_gemma":0.000028223676,"teacher_disagreement_score":0.50145465,"about_ca_system_score_codex":0.00011791626,"about_ca_system_score_gemma":0.00012322425,"threshold_uncertainty_score":0.9997698},"labels":[],"label_agreement":null},{"id":"W4317481674","doi":"10.1371/journal.pone.0280353","title":"Small-molecule inhibitors of proteasome increase CjCas9 protein stability","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Ataxia UK; Ataxia Canada; National Ataxia Foundation","keywords":"Bortezomib; HEK 293 cells; Transfection; MG132; Proteasome; Biology; Molecular biology; Proteasome inhibitor; Transgene; HeLa; Gene; Cell biology; Chemistry; Cell culture; Genetics; Immunology","score_opus":0.030056474315624585,"score_gpt":0.24874527050445555,"score_spread":0.21868879618883097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317481674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99857605,0.00018188702,0.00013443206,0.000081247235,0.000015779786,0.00061915803,0.000027222513,0.000044656357,0.00031955188],"genre_scores_gemma":[0.99852383,0.000022562746,0.0008211467,0.000013093625,0.00011005377,0.00014200583,0.00006496291,0.000024131637,0.0002781899],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991501,0.000035723653,0.00019411121,0.00025083357,0.0001588972,0.00021032106],"domain_scores_gemma":[0.99942774,0.0000059328586,0.0000446129,0.000358208,0.00007975778,0.000083776256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019515316,0.000114619375,0.00015228255,0.000046998266,0.000026770904,0.000007081313,0.000121639794,0.00009218073,0.000028478875],"category_scores_gemma":[0.00017111197,0.00011904035,0.000059818103,0.00017901663,0.000044281584,0.0000015450804,0.00013071233,0.00007273845,0.000017996113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030884003,0.00025686168,0.0028426412,0.00021811346,0.00006733152,0.0000024519225,0.000037248967,0.000010839979,0.9962562,0.000009214042,0.000051805255,0.00021646458],"study_design_scores_gemma":[0.00027138903,0.00020199985,0.0021533142,0.00005426366,0.000021851214,5.380206e-7,0.000052779294,0.000088044886,0.99689376,0.000022308466,0.00010649964,0.00013326603],"about_ca_topic_score_codex":0.000041827618,"about_ca_topic_score_gemma":0.000024488163,"teacher_disagreement_score":0.0006893272,"about_ca_system_score_codex":0.0000079600695,"about_ca_system_score_gemma":0.000050366296,"threshold_uncertainty_score":0.48543248},"labels":[],"label_agreement":null},{"id":"W4317492674","doi":"10.1101/2023.01.18.524633","title":"A multi-kingdom genetic barcoding system for precise target clone isolation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"CRISPR; Biology; Barcode; clone (Java method); Computational biology; DNA barcoding; Population; Genetics; Gene; Phenotype; Evolutionary biology; Computer science","score_opus":0.01998040965481572,"score_gpt":0.268056199175754,"score_spread":0.24807578952093828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317492674","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4738292,0.0018046821,0.5203508,0.000039588576,0.0019761948,0.0012660589,0.0004014598,0.00033070522,0.0000012993576],"genre_scores_gemma":[0.8864849,0.00016802819,0.11124364,0.000024395413,0.0011414544,0.00065999286,0.00000679891,0.00025361037,0.000017166774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99725395,0.00006876346,0.00059928786,0.0012096912,0.00023298494,0.0006353214],"domain_scores_gemma":[0.99793196,0.000035719175,0.0002806861,0.0011602244,0.00036408464,0.0002273482],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004903372,0.000570675,0.00048563804,0.00020528397,0.00017346082,0.00015025941,0.00049298373,0.0007098818,0.0000035975636],"category_scores_gemma":[0.00025813977,0.00067103724,0.0002788566,0.00021047314,0.000047308735,0.0000061784076,0.0005073198,0.00031527318,0.000025647121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043323238,0.00004370596,0.0019961463,0.0010182087,0.00017340222,0.00001011382,0.00000716458,0.009905477,0.9864892,0.000022111979,0.00028903392,0.0000021335923],"study_design_scores_gemma":[0.0011381704,0.00011687252,0.023789272,0.00053418765,0.00016584004,6.896961e-8,0.000007925075,0.036212116,0.93201107,0.0000011114661,0.004949632,0.0010737634],"about_ca_topic_score_codex":0.00002522232,"about_ca_topic_score_gemma":0.0000034883246,"teacher_disagreement_score":0.4126557,"about_ca_system_score_codex":0.00012973546,"about_ca_system_score_gemma":0.0002546274,"threshold_uncertainty_score":0.99957407},"labels":[],"label_agreement":null},{"id":"W4317538936","doi":"10.1139/bcb-2022-0243","title":"Evaluation of drug-free methods for the detection of gene silencing in <i>Saccharomyces cerevisiae</i>","year":2023,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Guelph","keywords":"URA3; Saccharomyces cerevisiae; Gene silencing; Gene; Gene expression; Biology; Computational biology; Drug; Genetics; Pharmacology","score_opus":0.01717913736361941,"score_gpt":0.35302916157846137,"score_spread":0.33585002421484195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317538936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705838,0.015912214,0.013024927,0.000032725442,0.000100276935,0.00018620673,0.000022251998,0.0000050690483,0.00013252175],"genre_scores_gemma":[0.9975173,0.00095384085,0.0013109351,0.0000070001506,0.0000730681,0.000051225106,0.000040277002,0.000006946367,0.000039444512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936765,0.000068609275,0.00019475378,0.00019518525,0.000052365118,0.00012142931],"domain_scores_gemma":[0.99948347,0.00008917698,0.0000766104,0.00023764836,0.00009506265,0.000018022994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012799439,0.00008330192,0.00011910357,0.000027358616,0.000026619397,0.0000022459735,0.00012839524,0.00011692031,0.0000030646574],"category_scores_gemma":[0.0002243011,0.00006798249,0.00005272466,0.00010734987,0.000059738202,0.0000010468844,0.00006223008,0.00003800037,1.308155e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002022949,0.000009160386,0.00014881774,0.00009483874,0.000018800316,2.5379771e-8,0.000044314842,0.00029831898,0.95336735,0.0000020944462,0.000024204888,0.04597186],"study_design_scores_gemma":[0.00050086394,0.00005959397,0.00040911493,0.000008803736,0.00005333285,0.0000015984556,0.0002573842,0.003319596,0.9944598,0.00012694272,0.0007315563,0.0000713878],"about_ca_topic_score_codex":0.00001665804,"about_ca_topic_score_gemma":0.0000067764254,"teacher_disagreement_score":0.04590047,"about_ca_system_score_codex":0.0000059618965,"about_ca_system_score_gemma":0.00003714558,"threshold_uncertainty_score":0.27722454},"labels":[],"label_agreement":null},{"id":"W4317781122","doi":"10.1002/ajmg.c.32032","title":"Gene‐targeted therapies: Towards equitable development, diagnosis, and access","year":2023,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part C Seminars in Medical Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Equity (law); Reimbursement; Disease; Psychological intervention; Medicine; Rare disease; Health care; Intensive care medicine; Business; Political science; Economic growth; Pathology; Psychiatry; Economics","score_opus":0.019250086578865188,"score_gpt":0.36240312984404405,"score_spread":0.34315304326517887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317781122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9622862,0.030425189,0.0047187787,0.0015773617,0.0007284531,0.00016615407,0.000009201312,0.000019504458,0.000069156486],"genre_scores_gemma":[0.7923411,0.19961125,0.005903777,0.0011567145,0.0007491864,0.000039558156,0.00004275176,0.000073577685,0.00008208782],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951204,0.00020269176,0.0011691174,0.00047832538,0.0021495011,0.00087997667],"domain_scores_gemma":[0.99782676,0.0001852378,0.00031696574,0.0003886079,0.00017480615,0.0011076031],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0028058907,0.00037793213,0.0006442811,0.00029907,0.00009532558,0.0000645443,0.0013321865,0.00039815088,0.00020460674],"category_scores_gemma":[0.0011499112,0.00033434998,0.00012997065,0.0007919253,0.00067973987,0.000007873232,0.0009086347,0.0006009948,0.000008012937],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010024438,0.00021674357,0.06291431,0.000080434795,0.00026804837,0.00041167496,0.00085472036,0.0011162594,0.004735339,0.000004433083,0.010747452,0.9185503],"study_design_scores_gemma":[0.005185047,0.003967734,0.10123097,0.0017082223,0.00018749264,0.0014173342,0.0031620224,0.006660286,0.23445442,0.00023925997,0.63979846,0.0019887174],"about_ca_topic_score_codex":0.000012062698,"about_ca_topic_score_gemma":0.000036261128,"teacher_disagreement_score":0.9165616,"about_ca_system_score_codex":0.000036133948,"about_ca_system_score_gemma":0.0010011428,"threshold_uncertainty_score":0.99991083},"labels":[],"label_agreement":null},{"id":"W4317781165","doi":"10.1007/978-1-0716-2982-6_16","title":"Interrogation of Functional miRNA-Target Interactions by CRISPR/Cas9 Genome Engineering","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Wellcome Trust","keywords":"CRISPR; Biology; Computational biology; microRNA; Cas9; Gene silencing; Guide RNA; Genome; Genetics; Genome engineering; Gene","score_opus":0.015589010850788692,"score_gpt":0.4095819477102664,"score_spread":0.3939929368594777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317781165","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14163807,0.0006356198,0.8569508,0.000075716445,0.0004073795,0.000097508746,0.00002304738,0.000025593154,0.0001462331],"genre_scores_gemma":[0.5854046,0.00010813562,0.41286597,0.00011495842,0.0001281899,0.00009144663,0.00082632137,0.00005322523,0.00040721288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989233,0.00015584088,0.0003020693,0.00031376645,0.00005441489,0.00025058357],"domain_scores_gemma":[0.9995473,0.000051581428,0.000058871716,0.000247203,0.000048647034,0.000046395664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048276025,0.00015035682,0.00018699761,0.00021581641,0.000019466008,0.000005528475,0.00014407563,0.00015136594,0.00004205713],"category_scores_gemma":[0.0001970289,0.00016474805,0.00009881153,0.0002976127,0.000041020015,0.0000027671967,0.00012532501,0.00014042,0.0000068556437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016916476,0.000020865986,0.00035586167,0.000017905924,0.000046968038,0.0000022429117,0.000038523827,0.014013362,0.98426294,0.00016544401,0.00018053896,0.0008784338],"study_design_scores_gemma":[0.0002799239,0.00011140063,0.001597953,0.000009776659,0.0000099144945,0.000012652986,0.0000838496,0.005121681,0.9682908,0.00023580741,0.024067748,0.00017845708],"about_ca_topic_score_codex":0.000013666419,"about_ca_topic_score_gemma":0.000005135084,"teacher_disagreement_score":0.44408485,"about_ca_system_score_codex":0.000023898676,"about_ca_system_score_gemma":0.000028170081,"threshold_uncertainty_score":0.6718231},"labels":[],"label_agreement":null},{"id":"W4317896878","doi":"10.1080/23299460.2023.2167572","title":"Governing gene-edited crops: risks, regulations, and responsibilities as perceived by agricultural genomics experts in Canada","year":2023,"lang":"en","type":"article","venue":"Journal of Responsible Innovation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"Columbia University","keywords":"Responsible Research and Innovation; Anticipation (artificial intelligence); Agriculture; Corporate governance; Genomics; Political science; Business; Biotechnology; Public relations; Engineering ethics; Engineering; Biology; Computer science; Genetics","score_opus":0.012582711127334072,"score_gpt":0.2919576991255534,"score_spread":0.27937498799821936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317896878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982749,0.00074579014,0.00016741193,0.0004976999,0.00018117244,0.00007564128,0.000016997335,0.0000049165433,0.000035435103],"genre_scores_gemma":[0.9980065,0.00053317496,0.0006331659,0.000084688174,0.00014111664,0.0000030253357,0.00008547209,0.000012241165,0.00050057506],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901897,0.0000684607,0.0004344279,0.0001338038,0.00019012226,0.0001542393],"domain_scores_gemma":[0.9993671,0.000056027315,0.00017663339,0.00010791094,0.00025438893,0.000037902337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044983262,0.00010193065,0.00013103189,0.00022675835,0.000054614968,0.000033350356,0.00007774604,0.00007380008,0.0000051810507],"category_scores_gemma":[0.00061768276,0.00009301147,0.000022918282,0.0005692233,0.00001938626,0.000016603817,0.000038922528,0.00010089266,5.998112e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000247689,0.0000055936794,0.005377735,0.000008925685,0.0000191149,0.000010626287,0.00026671548,0.004190595,0.98017395,0.000015288531,0.008631058,0.001052709],"study_design_scores_gemma":[0.00097231,0.00021813282,0.613359,0.000077461,0.000011657131,0.0001903742,0.006041345,0.0006935004,0.35722455,0.000092480834,0.02086258,0.00025661665],"about_ca_topic_score_codex":0.011752136,"about_ca_topic_score_gemma":0.025582757,"teacher_disagreement_score":0.6229494,"about_ca_system_score_codex":0.0001709348,"about_ca_system_score_gemma":0.0007577376,"threshold_uncertainty_score":0.9948287},"labels":[],"label_agreement":null},{"id":"W4317918630","doi":"10.3791/64209-v","title":"CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts","year":2022,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"CRISPR; Zebrafish; Genome editing; Cas9; Biology; Gene; Computational biology; Gene knockin; Genetics; Model organism; Forward genetics; Genetic screen; Phenotype","score_opus":0.014399663409183746,"score_gpt":0.4146239785933647,"score_spread":0.40022431518418095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317918630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945444,0.0037394494,0.00045533193,0.00007567185,0.00081189413,0.00015502263,0.000008600073,0.000004354066,0.00020526155],"genre_scores_gemma":[0.99876064,0.00014193426,0.00048679803,0.00016435707,0.00022456014,0.000024130817,0.000022257696,0.000026195208,0.00014913848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985894,0.00012359065,0.0005283402,0.00018433756,0.00031053438,0.00026382232],"domain_scores_gemma":[0.9995265,0.000017778799,0.00015033346,0.00015757476,0.000046045334,0.00010179402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040002394,0.00014190497,0.00025550276,0.00021224136,0.000041336407,0.000016106771,0.00021067167,0.00006730771,0.00015534011],"category_scores_gemma":[0.00009451771,0.00014953686,0.00010433087,0.00019623175,0.000016278265,0.000007416434,0.00015608287,0.00022181822,0.0000027275842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042447407,0.0004471789,0.0033391563,0.000008765085,0.00003812913,0.00009726316,0.00061687216,0.0019023969,0.9836929,0.0000031616776,0.009037966,0.00039177766],"study_design_scores_gemma":[0.0059501515,0.0009769663,0.00770239,0.00005010496,0.000010909246,0.00012643088,0.00085205,0.0004448121,0.91391695,0.000023525563,0.06963478,0.0003109255],"about_ca_topic_score_codex":0.000022708311,"about_ca_topic_score_gemma":0.000010036045,"teacher_disagreement_score":0.06977591,"about_ca_system_score_codex":0.00007221816,"about_ca_system_score_gemma":0.00008154045,"threshold_uncertainty_score":0.6097936},"labels":[],"label_agreement":null},{"id":"W4317936271","doi":"10.1002/cpz1.646","title":"Identifying Genetic Regulators of Protein‐Glycan Interactions with Genome‐Wide CRISPR Screening","year":2023,"lang":"en","type":"article","venue":"Current Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glycan; Biology; Computational biology; Glycosylation; CRISPR; Immune system; Gene; Genetics; Glycoprotein","score_opus":0.03587425920216512,"score_gpt":0.38304644434910756,"score_spread":0.3471721851469424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317936271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.789598,0.00034631367,0.17915687,0.000048132304,0.00013377919,0.030453712,0.000022980757,0.00009660191,0.00014363321],"genre_scores_gemma":[0.957739,0.000017115917,0.0045618787,0.000008572506,0.00021868148,0.03696152,0.00008518059,0.000055766814,0.00035230455],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884015,0.000032315394,0.00029835833,0.00034482748,0.0001894984,0.000294855],"domain_scores_gemma":[0.99925685,0.000008838233,0.000118479584,0.0004243458,0.000098621895,0.000092886046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013140259,0.00017982046,0.00016750704,0.00013179159,0.00008024671,0.0000355564,0.0002166519,0.000051861844,0.000022202852],"category_scores_gemma":[0.000051132698,0.00016807711,0.00008791926,0.00030988242,0.000055185425,0.000007248501,0.0001408033,0.00012561743,0.000011566856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016176412,0.000101780184,0.020528998,0.0007602579,0.00012139037,0.0000069066546,0.0002772278,0.0053050024,0.9506623,0.00004212594,0.0007181613,0.021314062],"study_design_scores_gemma":[0.0011730129,0.00046243827,0.09644161,0.00082013424,0.00003670302,0.000019081515,0.00028374253,0.00063473947,0.7933464,0.000074544034,0.10618648,0.00052108616],"about_ca_topic_score_codex":0.000006139514,"about_ca_topic_score_gemma":0.000011965857,"teacher_disagreement_score":0.17459498,"about_ca_system_score_codex":0.000011560825,"about_ca_system_score_gemma":0.00005334512,"threshold_uncertainty_score":0.6853986},"labels":[],"label_agreement":null},{"id":"W4317936687","doi":"10.1242/dev.200477","title":"Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in <i>Drosophila melanogaster</i>","year":2023,"lang":"en","type":"article","venue":"Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Sickkids Research Institute; Canadian Institutes of Health Research; Hospital for Sick Children; Consejo Nacional de Ciencia y Tecnología; Instituto Nacional de Cancerología","keywords":"Biology; EIF4E; Eukaryotic initiation factor; Spermatid; Initiation factor; Eukaryotic translation; Drosophila melanogaster; Genetics; Eukaryotic translation initiation factor 4 gamma; Cell biology; Translation (biology); Gene; Sperm; Messenger RNA","score_opus":0.035515662625765866,"score_gpt":0.3065135927426626,"score_spread":0.2709979301168967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317936687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98962647,0.0002048066,0.009247253,0.00024723305,0.00017567624,0.00030358564,0.00002510854,0.00002672234,0.00014315177],"genre_scores_gemma":[0.9955308,0.00010507638,0.0033771486,0.0001406234,0.00008159637,0.000087913104,0.00041575907,0.00002174863,0.00023934041],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926347,0.000010061612,0.00021098873,0.00022699306,0.00009063522,0.00019785654],"domain_scores_gemma":[0.999788,0.00001179929,0.000025849122,0.00011105452,0.000026068785,0.00003725021],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010621291,0.00010820346,0.00009271336,0.00008845961,0.00003780383,0.000011488286,0.000069019894,0.0000817206,0.000011000445],"category_scores_gemma":[0.000016540289,0.00011766447,0.0000400509,0.00014458764,0.000006904758,0.0000035518908,0.000022153676,0.000022191305,0.000022174305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007804609,0.00004081669,0.0148600675,0.00013089082,0.000055752032,0.0000044799267,0.0022892347,0.0011424407,0.9335396,0.0000134523725,0.0010831389,0.04676205],"study_design_scores_gemma":[0.0008804851,0.00006059648,0.17264287,0.00002554874,0.000007168855,0.0000025424781,0.00007088997,0.00083620776,0.79665697,0.00004649927,0.028513275,0.00025696194],"about_ca_topic_score_codex":0.0000016248841,"about_ca_topic_score_gemma":0.000024911269,"teacher_disagreement_score":0.1577828,"about_ca_system_score_codex":0.000020309035,"about_ca_system_score_gemma":0.000055234003,"threshold_uncertainty_score":0.4798218},"labels":[],"label_agreement":null},{"id":"W4318071523","doi":"10.1038/s41587-022-01624-4","title":"A universal deep-learning model for zinc finger design enables transcription factor reprogramming","year":2023,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pontifical Institute of Mediaeval Studies; University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Compute Canada; U.S. Department of Health and Human Services","keywords":"Zinc finger; Reprogramming; Computational biology; Transcription factor; Biology; Haploinsufficiency; Deep learning; Gene; Genetics; Computer science; Artificial intelligence; Phenotype","score_opus":0.01281029572412205,"score_gpt":0.28321297554292557,"score_spread":0.2704026798188035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318071523","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13167228,0.0016808687,0.865292,0.0005028166,0.00018818521,0.0003100843,0.000010955797,0.0003206963,0.000022138074],"genre_scores_gemma":[0.9704298,0.00044678012,0.027962502,0.0000492262,0.000101493926,0.000043415337,0.000106541964,0.000038706563,0.00082153454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990133,0.00001780098,0.00012434255,0.00042202094,0.00007017133,0.00035233327],"domain_scores_gemma":[0.99961114,0.000020095218,0.000037343463,0.0002441047,0.000048750684,0.000038594968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014626562,0.00015492072,0.00013057099,0.00016032602,0.00010359155,0.000014636939,0.00018197669,0.0012309293,0.000003206469],"category_scores_gemma":[0.00018024442,0.00016029309,0.00009538589,0.00022483946,0.00004846422,0.0000034067132,0.000056192872,0.0003800071,0.0000039675015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058545218,0.000011241046,0.000024509416,0.000026062773,0.00003833655,0.0000029491346,0.000074730386,0.024048427,0.9445834,0.0003993907,0.00039438714,0.030337999],"study_design_scores_gemma":[0.00051682035,0.00027853597,0.000058783044,0.000011088387,0.000023379454,0.000009993194,0.0001493424,0.20620629,0.72776514,0.00025714643,0.06447185,0.0002516211],"about_ca_topic_score_codex":0.0000018639432,"about_ca_topic_score_gemma":0.000012489377,"teacher_disagreement_score":0.8387575,"about_ca_system_score_codex":0.000017006292,"about_ca_system_score_gemma":0.000027764125,"threshold_uncertainty_score":0.9494054},"labels":[],"label_agreement":null},{"id":"W4318472573","doi":"10.37867/te1401141","title":"GENOME-WIDE IDENTIFICATION OF NICOTIANA TABACUM MIRNAS AND THEIR ROLE IN HUMAN HEALTH – A COMPUTATIONAL GENOMICS ASSESSMENT","year":2022,"lang":"en","type":"article","venue":"Towards Excellence","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact","funders":"","keywords":"Nicotiana tabacum; Genome; Biology; microRNA; Identification (biology); Genomics; Computational biology; Biotechnology; Genetics; Botany; Gene","score_opus":0.008579901545675967,"score_gpt":0.29679789151934044,"score_spread":0.2882179899736645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318472573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9774207,0.0019907479,0.020018768,0.00018137529,0.000042489548,0.00015502267,0.000054891316,0.000004732339,0.00013131458],"genre_scores_gemma":[0.99874026,0.00018495279,0.0007541067,0.00005503437,0.000020113328,0.000023983162,0.00012210479,0.000010276947,0.00008917282],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992708,0.000045053683,0.00024993243,0.00021273486,0.00009394232,0.00012751135],"domain_scores_gemma":[0.9996912,0.0000075559756,0.000089536494,0.00015111921,0.000021825557,0.000038751572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030086818,0.00008119189,0.00011079249,0.00005141087,0.00008533269,0.000008175555,0.00012750638,0.000018479122,0.000013657944],"category_scores_gemma":[0.0000059809877,0.00009066903,0.000029079676,0.00006666907,0.000031444553,0.000001970075,0.00015330648,0.000075486496,2.1255082e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009351242,0.00007953597,0.003972358,0.000046235218,0.00001661234,6.5391293e-7,0.00087273493,0.06607763,0.92627066,0.000059627786,0.00004392154,0.0025507049],"study_design_scores_gemma":[0.0011971132,0.00069394737,0.7820203,0.000019968036,0.000010888303,0.000035788395,0.004955002,0.025737174,0.17553324,0.0013811967,0.007911336,0.00050411007],"about_ca_topic_score_codex":0.00008915877,"about_ca_topic_score_gemma":0.000025612544,"teacher_disagreement_score":0.77804786,"about_ca_system_score_codex":0.00004775178,"about_ca_system_score_gemma":0.00011534109,"threshold_uncertainty_score":0.3697376},"labels":[],"label_agreement":null},{"id":"W4318476477","doi":"10.1007/978-1-0716-2970-3_22","title":"Gaining Wings to FLY: Using Drosophila Oogenesis as an Entry Point for Citizen Scientists in Laboratory Research","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Natural Sciences and Engineering Research Council of Canada","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute","keywords":"Citizen science; Crowdsourcing; Biorepository; Leverage (statistics); Drosophila (subgenus); Engineering ethics; Public relations; Political science; Sociology; Biology; Biobank; Engineering; Computer science; Genetics","score_opus":0.060364811074046065,"score_gpt":0.5284048548848994,"score_spread":0.46804004381085335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318476477","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68666816,0.00037736734,0.31203556,0.0001548948,0.00022819937,0.00037225813,0.000018058285,0.000020077436,0.00012545033],"genre_scores_gemma":[0.4312016,0.00005305957,0.56762487,0.0004571143,0.000176476,0.00019393502,0.000108444896,0.00007464828,0.00010986768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99714017,0.00085798063,0.0003345912,0.00078238454,0.00012746833,0.00075740117],"domain_scores_gemma":[0.9990677,0.00012232504,0.000035594265,0.00048272326,0.00014249321,0.00014911512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0049712933,0.00019066015,0.00026647892,0.0006713418,0.00009158652,0.0000302373,0.00035838658,0.00029700366,0.0000062898366],"category_scores_gemma":[0.0015918631,0.00021728402,0.000074502976,0.0012079469,0.000114565046,0.000004050356,0.00035063698,0.0001782031,0.000005655447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058847985,0.000024825693,0.0019762383,0.000025177447,0.000012118436,0.000029007475,0.00021063433,0.003227781,0.99009585,0.0004267668,0.000042905387,0.003869853],"study_design_scores_gemma":[0.00060246966,0.0003859401,0.0015024173,0.000038189602,0.0000064887004,0.000011013716,0.00026001263,0.0030315898,0.98500884,0.002747141,0.0061032996,0.00030262303],"about_ca_topic_score_codex":0.00006803359,"about_ca_topic_score_gemma":0.000035978897,"teacher_disagreement_score":0.2555893,"about_ca_system_score_codex":0.000059239366,"about_ca_system_score_gemma":0.00014118005,"threshold_uncertainty_score":0.8860585},"labels":[],"label_agreement":null},{"id":"W4318620185","doi":"10.5772/intechopen.109712","title":"Involvement of CRISPR-Cas Systems in <i>Salmonella</i> Immune Response, Genome Editing, and Pathogen Typing in Diagnosis and Surveillance","year":2023,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada; Canadian Food Inspection Agency","funders":"Public Health Agency; Public Health Agency of Canada; Canadian Food Inspection Agency","keywords":"CRISPR; Biology; Salmonella; Genome; Computational biology; Genome editing; Genetics; Gene; Bacteria","score_opus":0.01573294982201367,"score_gpt":0.26760993983821846,"score_spread":0.2518769900162048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318620185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8121826,0.110624425,0.0016335014,0.00015929906,0.0014549351,0.00424368,0.0007957891,0.00009958855,0.068806194],"genre_scores_gemma":[0.9723715,0.0051686997,0.00008891955,0.00003310909,0.0001488406,0.00015163553,0.000080177444,0.00011280528,0.021844268],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986075,0.000045919456,0.00054583006,0.0004622677,0.00010840532,0.00023005412],"domain_scores_gemma":[0.9993225,0.00006816715,0.00015937949,0.00033956082,0.000054977907,0.00005542867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000727386,0.0002796831,0.0004440733,0.00021294659,0.000021731843,0.00002776795,0.00017354074,0.0003236607,0.0000033281399],"category_scores_gemma":[0.00008072826,0.00030761634,0.00005627679,0.000024183275,0.000086466294,0.0000019151269,0.0003819281,0.00022764849,0.0000018723869],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044666388,0.000023962864,0.0045593427,0.000855365,0.00017343085,0.000120971505,0.0006653056,0.00033825348,0.9841755,0.00046734538,0.00016049056,0.008013378],"study_design_scores_gemma":[0.007220148,0.0026389672,0.059973676,0.010130796,0.00016479172,0.00023242852,0.002400883,0.0005913025,0.4518847,0.0016243377,0.45791426,0.0052237315],"about_ca_topic_score_codex":0.0002503138,"about_ca_topic_score_gemma":0.00056683976,"teacher_disagreement_score":0.5322908,"about_ca_system_score_codex":0.000032949087,"about_ca_system_score_gemma":0.000040893174,"threshold_uncertainty_score":0.9999376},"labels":[],"label_agreement":null},{"id":"W4318761571","doi":"10.1016/j.jmb.2023.167991","title":"Anti-CRISPR Protein AcrIIC5 Inhibits CRISPR-Cas9 by Occupying the Target DNA Binding Pocket","year":2023,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Cas9; DNA; RNA; Biology; Trans-activating crRNA; Computational biology; Chemistry; Biochemistry; Gene","score_opus":0.00808798688406444,"score_gpt":0.32643323942677627,"score_spread":0.31834525254271184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318761571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96077263,0.0033297841,0.03390884,0.0011339175,0.00044720597,0.00022855506,0.000035388544,0.00002088251,0.00012277873],"genre_scores_gemma":[0.9972425,0.0003006878,0.0013358182,0.00046698636,0.00032469787,0.000012769857,0.00008237497,0.00004853031,0.00018564191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824846,0.00018968605,0.0005345541,0.0003095366,0.00019546409,0.000522284],"domain_scores_gemma":[0.9990578,0.00002858376,0.00027258246,0.00035128012,0.00015520175,0.000134528],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007768267,0.00026282846,0.0003365653,0.00017177386,0.00013826939,0.000040220595,0.00048244075,0.00026930502,0.000026403313],"category_scores_gemma":[0.0003304317,0.0001953202,0.00026062145,0.00033155776,0.00010594233,0.000006714562,0.0002270844,0.0003429188,0.000024574152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003627993,0.000027557782,0.0006579055,0.000019230809,0.00014146976,0.000048077283,0.00004776017,0.00028599254,0.9877592,0.00004290948,0.010114549,0.00081909867],"study_design_scores_gemma":[0.00054820586,0.0003834231,0.00026555537,0.000034978722,0.000032184766,0.00018794226,0.00014972597,0.00006285583,0.9512794,0.0001665374,0.04665663,0.00023256417],"about_ca_topic_score_codex":0.000004777105,"about_ca_topic_score_gemma":0.0000011701419,"teacher_disagreement_score":0.036542084,"about_ca_system_score_codex":0.000019673802,"about_ca_system_score_gemma":0.00008860954,"threshold_uncertainty_score":0.79649264},"labels":[],"label_agreement":null},{"id":"W4319297108","doi":"10.3390/curroncol30020152","title":"Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Gene; Genetic enhancement; Medicine; Biology; Bioinformatics; Genetics","score_opus":0.06835177538779742,"score_gpt":0.4840187306555901,"score_spread":0.4156669552677927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319297108","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015576938,0.99676394,0.001000332,0.00004996105,0.0012234554,0.0006481846,0.000077600205,0.000027744223,0.000053038064],"genre_scores_gemma":[0.0002332345,0.9972186,0.00005091095,0.0000017415605,0.00071954343,0.0012373336,0.0004043625,0.000043276596,0.00009096913],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99879867,0.000057893256,0.00042740442,0.00043584654,0.00005337296,0.00022680285],"domain_scores_gemma":[0.99935013,0.000017665207,0.00021813007,0.00033169411,0.000046096953,0.00003627479],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008355899,0.00026553244,0.0008238414,0.00034154963,0.00001921994,0.0000025984789,0.00017381326,0.0006691273,0.000004963722],"category_scores_gemma":[0.00002247797,0.00023496067,0.00019644877,0.00049214676,0.00004939605,9.924445e-7,0.000080210964,0.00019269412,0.000012262362],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005844133,0.0001290435,0.00010563758,0.0023625947,0.000074007956,0.0000014501096,0.000017263854,0.000020676593,0.0002627135,0.000034559496,0.00023885604,0.9967474],"study_design_scores_gemma":[0.00025825546,0.00025625242,0.000028183862,0.0005992231,0.00019298003,0.000013770303,0.000023969731,0.000026960854,0.00045995746,0.000021027732,0.99793845,0.00018093982],"about_ca_topic_score_codex":0.000032911346,"about_ca_topic_score_gemma":0.00033500328,"teacher_disagreement_score":0.9976996,"about_ca_system_score_codex":0.00019848601,"about_ca_system_score_gemma":0.00023426133,"threshold_uncertainty_score":0.9581418},"labels":[],"label_agreement":null},{"id":"W4319442778","doi":"10.1016/j.bcp.2023.115449","title":"CRISPR/Cas genome editing in triple negative breast cancer: Current situation and future directions","year":2023,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Fundamental Research Funds for the Central Universities; Sichuan University","keywords":"CRISPR; Genome editing; Triple-negative breast cancer; Computational biology; Breast cancer; Biology; Gene; Cas9; Suppressor; Cancer; Cancer research; Genetics","score_opus":0.02446667993235144,"score_gpt":0.4018602858354646,"score_spread":0.37739360590311316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319442778","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009484231,0.99573827,0.00007345354,0.00016473365,0.0020678733,0.0005868186,0.00036842356,0.000035492667,0.000016495751],"genre_scores_gemma":[0.00040110445,0.9926733,0.000039493163,0.000034333723,0.0058555324,0.0004157861,0.00047834602,0.00005766164,0.00004448583],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984086,0.00009575066,0.00041460493,0.00059739,0.00008782963,0.0003957855],"domain_scores_gemma":[0.9994945,0.000042597785,0.00014066137,0.00013829571,0.000054563952,0.00012938888],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015123317,0.00034795635,0.00061530847,0.00015983263,0.00006475042,0.000015347334,0.00016359956,0.00041950095,0.00004274929],"category_scores_gemma":[0.00003116392,0.00033983387,0.00016789995,0.00032675182,0.000072684634,0.0000031595562,0.0002139421,0.00042782602,0.000010194449],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040916482,0.00014925378,0.000010591032,0.0068711317,0.00042076633,0.000013746374,0.000145105,0.000016911494,0.043500487,0.0000069195557,0.041242167,0.907582],"study_design_scores_gemma":[0.00044678917,0.000025535248,0.000113395865,0.00039047026,0.00034144524,0.000047242225,0.000027232516,0.000029699702,0.002858646,0.000007719004,0.9953435,0.0003683252],"about_ca_topic_score_codex":0.000028257593,"about_ca_topic_score_gemma":0.000012203189,"teacher_disagreement_score":0.9541013,"about_ca_system_score_codex":0.000098127995,"about_ca_system_score_gemma":0.00012985179,"threshold_uncertainty_score":0.99990535},"labels":[],"label_agreement":null},{"id":"W4319598375","doi":"10.3390/cells12040536","title":"Prime Editing for Human Gene Therapy: Where Are We Now?","year":2023,"lang":"en","type":"review","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Genome editing; Genetic enhancement; CRISPR; Cas9; Disease; Gene; Computational biology; Medicine; Bioinformatics; Genetics; Biology; Pathology","score_opus":0.04967443153097665,"score_gpt":0.3755295736144998,"score_spread":0.3258551420835231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319598375","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000020237741,0.99624777,0.0020845137,0.000023432836,0.0006430433,0.000670199,0.0001382331,0.0000390002,0.00013359699],"genre_scores_gemma":[0.000008140917,0.9905854,0.00038815974,0.000014537816,0.00253593,0.00017453263,0.00047062343,0.00014384193,0.005678872],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988247,0.000024590689,0.00031261632,0.00044761726,0.000080163,0.00031030076],"domain_scores_gemma":[0.99927175,0.00002156775,0.00016572342,0.00042842215,0.000042990774,0.00006955982],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001332263,0.0003261334,0.00058444624,0.00005145539,0.00007691518,0.000031627238,0.00027609328,0.0003714568,0.000016917269],"category_scores_gemma":[0.000007462968,0.00029500888,0.00043311084,0.0000778015,0.000020705782,7.65901e-7,0.000098732286,0.00012876617,0.000049062568],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005880716,0.000061784194,0.0000019191127,0.024726337,0.00066565437,0.000017830895,0.00004019569,0.0000625281,0.09900623,0.000010381275,0.103391364,0.7720099],"study_design_scores_gemma":[0.00014659243,0.000063441476,2.7409868e-7,0.0016032938,0.00009256803,0.0000055557093,0.000010989716,0.0000029813968,0.034751356,0.000008762152,0.9630117,0.0003025278],"about_ca_topic_score_codex":0.0000016110536,"about_ca_topic_score_gemma":0.000012368604,"teacher_disagreement_score":0.8596203,"about_ca_system_score_codex":0.000014814512,"about_ca_system_score_gemma":0.000054544373,"threshold_uncertainty_score":0.99995023},"labels":[],"label_agreement":null},{"id":"W4319599833","doi":"10.3390/v15020465","title":"Specialized DNA Structures Act as Genomic Beacons for Integration by Evolutionarily Diverse Retroviruses","year":2023,"lang":"en","type":"review","venue":"Viruses","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs","keywords":"Provirus; Biology; Genome; Genetics; Integrase; DNA; Computational biology; Virology; Gene","score_opus":0.051023776582468525,"score_gpt":0.38534342927474907,"score_spread":0.33431965269228053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319599833","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00065614353,0.9939634,0.0020134107,0.000008248459,0.00076402596,0.0008234763,0.0016103251,0.00006417224,0.000096747994],"genre_scores_gemma":[0.0001246232,0.99530137,0.00045273796,0.00013409033,0.0010687071,0.0001637938,0.0020142382,0.00010921184,0.00063120684],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986429,0.000049856746,0.00039020856,0.00050728023,0.00012352312,0.000286199],"domain_scores_gemma":[0.9992426,0.00007906571,0.00017220395,0.00037305724,0.000051084855,0.00008198617],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010346435,0.00039721793,0.0006188512,0.00011718842,0.00011779468,0.000055912817,0.00029739673,0.0004164847,0.000046118403],"category_scores_gemma":[0.00033402047,0.00035341945,0.00041852886,0.000118181866,0.000060916267,0.000004617327,0.00013103124,0.00013566522,0.00006287254],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013403683,0.000063796455,0.000016669224,0.004273425,0.001230325,0.0000058291207,0.000060387647,0.000042604686,0.11665241,0.0006309537,0.30188775,0.57500184],"study_design_scores_gemma":[0.00022190457,0.000120049976,0.00001045534,0.00034807067,0.0003532342,0.000007698936,0.00002415356,0.000002043742,0.006857799,0.00009715829,0.9915756,0.00038181274],"about_ca_topic_score_codex":0.00007075672,"about_ca_topic_score_gemma":0.00006609126,"teacher_disagreement_score":0.68968785,"about_ca_system_score_codex":0.00006225943,"about_ca_system_score_gemma":0.0001808104,"threshold_uncertainty_score":0.99989176},"labels":[],"label_agreement":null},{"id":"W4319748369","doi":"10.1038/s41598-023-29332-2","title":"The PROTECTOR strategy employs dCas orthologs to sterically shield off-target sites from CRISPR/Cas activity","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Computational biology; Biology; Steric effects; Bioinformatics; Genetics; Chemistry; Gene","score_opus":0.018070320352186076,"score_gpt":0.3149696633384549,"score_spread":0.2968993429862688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319748369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99104166,0.00028806351,0.005475165,0.00035602084,0.002007655,0.0004362014,0.00001664222,0.00007899302,0.00029960964],"genre_scores_gemma":[0.9949105,0.00001762539,0.0005010225,0.00004029171,0.00019457864,0.00008574747,0.00011311628,0.00002553404,0.004111623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981503,0.000048671674,0.00028441715,0.00078894274,0.0003000132,0.00042768157],"domain_scores_gemma":[0.998617,0.000031869335,0.00009562464,0.0010022182,0.00009746919,0.00015584717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074508094,0.00017556148,0.00014605466,0.00006136252,0.00035021332,0.00027582014,0.00022499975,0.00011430381,0.000034311754],"category_scores_gemma":[0.00034434526,0.00013415904,0.00010744173,0.00038975934,0.00010946855,0.000006424401,0.0002612457,0.000115521936,0.00005343113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025396756,0.000021858665,0.0040535782,0.000007047753,0.000028108689,0.000118341246,0.00011221478,0.0009349965,0.9702628,0.000002164465,0.018172154,0.006261314],"study_design_scores_gemma":[0.00008018967,0.00015004883,0.03412731,0.000009621935,0.000011824869,0.00003883851,0.000109916524,0.00019603402,0.85246384,0.00057350873,0.111978725,0.00026011374],"about_ca_topic_score_codex":0.000046702702,"about_ca_topic_score_gemma":0.00025040828,"teacher_disagreement_score":0.11779896,"about_ca_system_score_codex":0.000012959621,"about_ca_system_score_gemma":0.00010046254,"threshold_uncertainty_score":0.5470847},"labels":[],"label_agreement":null},{"id":"W4319940560","doi":"10.1016/j.bpj.2022.11.728","title":"Characterization of atrial fibrillation linked mutations using the Nav1.5 knock-out of atrial cardiomyocytes derived from iPSCs","year":2023,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Atrial fibrillation; Gene knockin; Induced pluripotent stem cell; Internal medicine; Medicine; Biology; Genetics; Gene","score_opus":0.019694190872207647,"score_gpt":0.3021220541019726,"score_spread":0.282427863229765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319940560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9794046,0.00010341524,0.019698882,0.00004165608,0.000580359,0.00009392401,0.000065790686,0.0000070082256,0.000004349478],"genre_scores_gemma":[0.9951812,0.00020430045,0.00035724972,0.0000036307931,0.004046026,4.1050353e-7,0.00018517039,0.000013128741,0.000008882156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992841,0.000059550184,0.00027517506,0.00011128653,0.00015588306,0.000114036186],"domain_scores_gemma":[0.99951416,0.0000374645,0.00016772389,0.00012999386,0.000111040186,0.000039595314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098437544,0.00008812783,0.00015586049,0.00004009642,0.000077633566,0.000019411118,0.00009531506,0.000081996695,0.00000540746],"category_scores_gemma":[0.000080833146,0.000070399234,0.0002990253,0.00013781832,0.00005176881,0.000005626764,0.00004875141,0.00007167884,0.000002088358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086401844,0.0000033461251,0.00038285655,0.0000055882315,0.00012517111,7.5347606e-7,0.00013073767,0.0127609745,0.9840592,0.0000039947454,0.000005994822,0.0024349664],"study_design_scores_gemma":[0.0006315622,0.000098410615,0.013783258,0.000022033511,0.00011825866,0.000005021521,0.000084110434,0.010140488,0.9744227,0.000032786375,0.0005621424,0.00009921006],"about_ca_topic_score_codex":0.000015976055,"about_ca_topic_score_gemma":0.0000016588685,"teacher_disagreement_score":0.019341633,"about_ca_system_score_codex":0.000008686117,"about_ca_system_score_gemma":0.00005702743,"threshold_uncertainty_score":0.28707975},"labels":[],"label_agreement":null},{"id":"W4320921326","doi":"10.1016/j.ymthe.2023.02.009","title":"A luciferase reporter mouse model to optimize in vivo gene editing validated by lipid nanoparticle delivery of adenine base editors","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; FPInnovations; University of British Columbia","funders":"Genome British Columbia; Michael Smith Health Research BC","keywords":"Luciferase; Bioluminescence imaging; Bioluminescence; Reporter gene; CRISPR; In vivo; Genome editing; Gene; Gene delivery; Genome; Molecular biology; Chemistry; Computational biology; Biology; Genetic enhancement; Biochemistry; Genetics; Gene expression; Transfection","score_opus":0.01069780590812608,"score_gpt":0.2722018175366011,"score_spread":0.26150401162847503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320921326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9774256,0.00027641654,0.021497615,0.00018493053,0.00024108407,0.00025042376,0.00006173682,0.00003985425,0.000022360962],"genre_scores_gemma":[0.99532396,0.00017376243,0.0032314062,0.00031272438,0.00034459867,0.00006801687,0.00011537225,0.000059844515,0.0003703311],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865663,0.00004274358,0.00036389488,0.00039709813,0.00019798873,0.0003416536],"domain_scores_gemma":[0.99928796,0.000007900931,0.00006375841,0.00043603498,0.00007783696,0.00012651585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024640674,0.00019095495,0.00020439998,0.00011039674,0.000028090042,0.000016370248,0.00016933867,0.00011756971,0.00001896483],"category_scores_gemma":[0.00005228545,0.00020152051,0.0000972212,0.00029148624,0.000022664517,0.000004874503,0.00008759283,0.00006585961,0.000004648661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000098590484,0.000059695605,0.00013046208,0.000007486347,0.000034963,0.000025522695,0.00008956298,0.14379829,0.8474881,5.729593e-7,0.0080363015,0.00023043188],"study_design_scores_gemma":[0.0009258046,0.00016150711,0.0000195232,0.000011186325,0.000006899262,0.0000043776895,0.00003566243,0.021510577,0.97532576,0.0000039496117,0.0017885055,0.00020626473],"about_ca_topic_score_codex":0.00002902107,"about_ca_topic_score_gemma":0.000004126193,"teacher_disagreement_score":0.12783763,"about_ca_system_score_codex":0.000013695809,"about_ca_system_score_gemma":0.000037090926,"threshold_uncertainty_score":0.82177675},"labels":[],"label_agreement":null},{"id":"W4321110701","doi":"10.21203/rs.3.rs-2520557/v1","title":"Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Karolinska Institutet; Johns Hopkins University","keywords":"Dopaminergic; Chromatin; Biology; Neuroscience; Midbrain; Cell culture; Computational biology; Cell biology; Dopamine; Genetics; Gene; Central nervous system","score_opus":0.12150527253423514,"score_gpt":0.49092244871701857,"score_spread":0.3694171761827834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321110701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869395,0.0031051,0.0022149999,0.002002643,0.00059217704,0.0043186387,0.0004095207,0.00010657049,0.00031087993],"genre_scores_gemma":[0.9439445,0.00051167415,0.001245625,0.00008707242,0.0017302457,0.0037376168,0.0015224349,0.0002345192,0.0469863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965726,0.00041074032,0.00035974465,0.0009566726,0.00071264437,0.0009875775],"domain_scores_gemma":[0.9975928,0.00036760495,0.0000813889,0.001223743,0.00055773003,0.00017673719],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002592629,0.0003427886,0.0002741715,0.00016130669,0.0003327035,0.00021771122,0.00087787566,0.00039553683,0.000019222862],"category_scores_gemma":[0.003400441,0.00027493923,0.0002914813,0.00025727734,0.00012901917,0.0000032980827,0.0016861357,0.0010174803,0.000033348264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006155978,0.00023727777,0.00081021455,0.0033337534,0.00032484427,0.00002586867,0.0006914534,0.1690227,0.7792969,0.00022299183,0.039240442,0.006178008],"study_design_scores_gemma":[0.0024359901,0.0073107453,0.0018602753,0.0005909165,0.00014746716,0.00004624344,0.0013302643,0.43562865,0.487512,0.0014640808,0.060025167,0.0016482129],"about_ca_topic_score_codex":0.0001484617,"about_ca_topic_score_gemma":0.00013484019,"teacher_disagreement_score":0.29178485,"about_ca_system_score_codex":0.000044162753,"about_ca_system_score_gemma":0.00044139093,"threshold_uncertainty_score":0.99997026},"labels":[],"label_agreement":null},{"id":"W4321375288","doi":"10.3390/fishes8020116","title":"Editing the Melanocortin-4 Receptor Gene in Channel Catfish Using the CRISPR-Cas9 System","year":2023,"lang":"en","type":"article","venue":"Fishes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Food and Agriculture; U.S. Department of Agriculture","keywords":"Catfish; Ictalurus; Biology; Zebrafish; Microinjection; CRISPR; Gene; Cas9; Melanocortin 4 receptor; Aquaculture; Genetics; Fishery; Cell biology; Receptor; Melanocortin; Fish <Actinopterygii>","score_opus":0.018294140787182403,"score_gpt":0.28960359672915004,"score_spread":0.27130945594196765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321375288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995278,0.00064380874,0.0019066785,0.0005838783,0.0008269037,0.000232599,0.000017749971,0.000046923265,0.00046347763],"genre_scores_gemma":[0.99818,0.00007273747,0.00012371445,0.00010180427,0.0011551863,0.000043564756,0.00004751133,0.000026245196,0.0002492917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914277,0.00004737541,0.00019310348,0.00021746896,0.000110044224,0.0002892356],"domain_scores_gemma":[0.999546,0.000027774238,0.000049434773,0.0003131422,0.000031641077,0.00003202896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034580773,0.00012085627,0.00010236081,0.000032819127,0.00014124029,0.00003842471,0.00023918202,0.00008352819,0.0000064952296],"category_scores_gemma":[0.00009469811,0.00007994648,0.00006189329,0.00022154454,0.00003429633,0.0000024550216,0.00013756096,0.000106699204,0.000015972751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030526866,0.000025626656,0.008289657,0.00017112528,0.00010828979,0.0000258113,0.001968469,0.028322976,0.9186745,0.00005794081,0.03969959,0.0026254277],"study_design_scores_gemma":[0.0005808707,0.0000988027,0.01753977,0.0001516081,0.000048830447,0.00009500401,0.009024456,0.030165693,0.8778749,0.000026724356,0.06386331,0.0005299956],"about_ca_topic_score_codex":0.00008756791,"about_ca_topic_score_gemma":0.000086742555,"teacher_disagreement_score":0.040799618,"about_ca_system_score_codex":0.000017726288,"about_ca_system_score_gemma":0.000023118972,"threshold_uncertainty_score":0.3260123},"labels":[],"label_agreement":null},{"id":"W4321503536","doi":"10.1016/j.aca.2023.340998","title":"CRISPR-Cas12a-assisted elimination of the non-specific signal from non-specific amplification in the Exponential Amplification Reaction","year":2023,"lang":"en","type":"article","venue":"Analytica Chimica Acta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Key Research and Development Program of China Stem Cell and Translational Research; National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Chemistry; Nucleic acid; CRISPR; Template; SIGNAL (programming language); Computational biology; Nanotechnology; Gene; Biochemistry; Computer science; Biology","score_opus":0.019188006660521655,"score_gpt":0.2869835020934662,"score_spread":0.2677954954329445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321503536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99233466,0.000035296307,0.005122028,0.0013856735,0.00023313468,0.00039265436,0.000034760396,0.000019166775,0.0004426413],"genre_scores_gemma":[0.9981296,0.00054762233,0.00017653038,0.00005655776,0.00029203796,0.00004903558,0.0006573839,0.000025349622,0.00006587137],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99850506,0.00008901108,0.0004333203,0.0004281347,0.00030837368,0.0002361069],"domain_scores_gemma":[0.99880624,0.00007405207,0.00018146884,0.0008002847,0.00009942079,0.000038557006],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003526217,0.00018005935,0.00016661342,0.00013583331,0.00011676902,0.000048838563,0.00046113553,0.00016218415,0.00002111875],"category_scores_gemma":[0.000041068517,0.00013728715,0.00015411689,0.000644835,0.00007768009,0.000012056942,0.00007488139,0.00017761988,0.000024498499],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005344361,0.00008201269,0.00023107894,0.000009067853,0.000029585264,4.3445672e-7,0.00033623143,0.000066312525,0.9922958,0.000077473334,0.004196676,0.0026218737],"study_design_scores_gemma":[0.0004423242,0.000057465037,0.55257535,0.000031911426,0.000045821984,0.000003914947,0.0006222174,0.0038209292,0.43373024,0.00013612965,0.008336386,0.00019730638],"about_ca_topic_score_codex":0.00003449959,"about_ca_topic_score_gemma":0.000045938323,"teacher_disagreement_score":0.55856556,"about_ca_system_score_codex":0.00003543766,"about_ca_system_score_gemma":0.000025397698,"threshold_uncertainty_score":0.55984074},"labels":[],"label_agreement":null},{"id":"W4321607200","doi":"10.1101/2023.02.22.529427","title":"Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Allele; Computational biology; Biology; Genetics; Biotechnology; Gene","score_opus":0.02462805910909531,"score_gpt":0.2739910321324538,"score_spread":0.24936297302335847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321607200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8638321,0.0045160074,0.12642914,0.0003675574,0.0020233202,0.0015870015,0.00065994816,0.00057763816,0.000007278097],"genre_scores_gemma":[0.9833675,0.00093072257,0.013072601,0.00020369464,0.0012862094,0.0006786926,0.00001589065,0.00034293433,0.000101778984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969468,0.0000759893,0.0006020837,0.0013121457,0.00025327626,0.00080971123],"domain_scores_gemma":[0.9975997,0.00006506466,0.00026741312,0.0014460345,0.0003321616,0.00028960578],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048276337,0.000712703,0.0006003213,0.00014213227,0.00018853365,0.00028515648,0.00072374207,0.0008037776,0.000021506174],"category_scores_gemma":[0.00050961494,0.00079772173,0.0003552387,0.00025298452,0.00010749355,0.000014590649,0.00081458414,0.00052394456,0.000036669055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079207915,0.000030892814,0.00071138894,0.0005437437,0.00035711515,0.00003360572,0.000015207427,0.0031169853,0.99395716,0.000104193394,0.0010449467,0.000005555526],"study_design_scores_gemma":[0.0010254326,0.00011962396,0.008499266,0.00029168295,0.0001655742,6.2728446e-8,0.000010572779,0.0020564906,0.9783938,0.000009913912,0.008223513,0.001204082],"about_ca_topic_score_codex":0.000047580706,"about_ca_topic_score_gemma":0.000017642355,"teacher_disagreement_score":0.119535364,"about_ca_system_score_codex":0.000092190174,"about_ca_system_score_gemma":0.000735444,"threshold_uncertainty_score":0.99944735},"labels":[],"label_agreement":null},{"id":"W4321763815","doi":"10.3791/64793","title":"Rapid Development of Cell State Identification Circuits with Poly-Transfection","year":2023,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"British Columbia Institute of Technology; University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Transfection; Flow cytometry; Electronic circuit; Population; Computer science; Cell culture; Biological system; Biology; Molecular biology; Physics; Genetics; Medicine","score_opus":0.017885684603809408,"score_gpt":0.38525190499283907,"score_spread":0.36736622038902966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321763815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9385497,0.0009667725,0.06015753,0.0000052483783,0.00017414447,0.000075223616,0.0000018787762,0.0000060390084,0.000063437816],"genre_scores_gemma":[0.9980531,0.00026167778,0.0014168447,0.000007743853,0.000045887547,0.000005216053,0.00001616999,0.000016683412,0.00017671213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917084,0.000025427995,0.0003776962,0.00010234961,0.00020165065,0.000122020996],"domain_scores_gemma":[0.9995552,0.0000043702807,0.0001788251,0.00009808777,0.00010865555,0.000054892193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023160869,0.000088261506,0.00012809438,0.00011180129,0.000034459146,0.000011195517,0.00008749646,0.00003948604,0.000010986681],"category_scores_gemma":[0.000008057814,0.00007743589,0.0000535823,0.00013633605,0.000015220237,0.0000057306547,0.00001572616,0.000041650634,0.000003941032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000116226955,0.00007380158,0.00015554266,0.000027951466,0.000071280796,0.00000221108,0.0008646943,0.0001435597,0.9925971,6.547177e-7,0.00010530434,0.005841691],"study_design_scores_gemma":[0.001030027,0.00026405754,0.0041287225,0.000028244509,0.000012298673,0.00001056339,0.0002787359,0.00003221021,0.9919391,0.0000025620595,0.0021876644,0.00008579719],"about_ca_topic_score_codex":0.0000011488635,"about_ca_topic_score_gemma":8.52731e-7,"teacher_disagreement_score":0.05950334,"about_ca_system_score_codex":0.0000151851045,"about_ca_system_score_gemma":0.000070497816,"threshold_uncertainty_score":0.3157744},"labels":[],"label_agreement":null},{"id":"W4321763871","doi":"10.3791/64793-v","title":"JoVE Video Dataset","year":2023,"lang":"pt","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transfection; Flow cytometry; Electronic circuit; Computer science; Population; Biological system; Cytometry; Cell culture; Chemistry; Molecular biology; Biology; Genetics; Electrical engineering; Engineering","score_opus":0.013158282106104332,"score_gpt":0.33046469911921283,"score_spread":0.3173064170131085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321763871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71647775,0.026199564,0.14098433,0.0124123925,0.012992902,0.002676483,0.030693622,0.0009849853,0.056577973],"genre_scores_gemma":[0.94746315,0.0016898698,0.0002456871,0.0006651113,0.0006847688,0.000017214616,0.013452942,0.000059405585,0.03572187],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988323,0.000020929692,0.00020003926,0.0004185073,0.00012432289,0.0004039159],"domain_scores_gemma":[0.999193,0.000013508816,0.000026548687,0.000602628,0.00002687596,0.00013743133],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016509075,0.0001969182,0.00013905906,0.00006411414,0.000060724517,0.000039156686,0.00023163523,0.00018596518,0.00035529578],"category_scores_gemma":[0.000061162886,0.00019953863,0.000083648396,0.00022651468,0.00003321782,0.0000018162498,0.0003112983,0.00009275582,0.0013715494],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015426913,0.000021566268,0.00027046417,0.000053421347,0.000080283695,0.000017913868,0.000040928804,0.0008419489,0.1964776,0.00004975932,0.7989576,0.0031731087],"study_design_scores_gemma":[0.00038197634,0.00013903668,0.0014593411,0.000013552254,0.00003214128,0.00001274447,0.00021700781,0.0022595439,0.17755234,0.0000141787095,0.8175891,0.0003290107],"about_ca_topic_score_codex":0.000024022298,"about_ca_topic_score_gemma":0.00004779978,"teacher_disagreement_score":0.23098537,"about_ca_system_score_codex":0.000006916527,"about_ca_system_score_gemma":0.00004257159,"threshold_uncertainty_score":0.999406},"labels":[],"label_agreement":null},{"id":"W4322097221","doi":"10.2139/ssrn.3498384","title":"La gouvernance des techniques d’édition du génome humain : CRISPR-Cas9 en tant que plateforme? (Governance of Human Genome Editing Techniques: CRISPR-Cas9 as a Platform?)","year":2023,"lang":"fr","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"CRISPR; Genome editing; Biology; Political science; Computational biology; Genetics; Gene","score_opus":0.0056007009832399045,"score_gpt":0.2791236375447375,"score_spread":0.2735229365614976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322097221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89625204,0.032790937,0.06464759,0.00075575925,0.00062621007,0.0006973396,0.00018270798,0.00021792534,0.003829491],"genre_scores_gemma":[0.90107095,0.093132935,0.0010372071,0.00005735922,0.0021669902,0.00006509292,0.000092017384,0.00013806176,0.002239383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9947484,0.00018703735,0.0010456499,0.0006251161,0.0005223487,0.0028714424],"domain_scores_gemma":[0.99826825,0.000073485666,0.00070564507,0.0004726959,0.00027533155,0.00020462181],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0031608385,0.00060962257,0.00058774365,0.00023403946,0.00052774895,0.00010591813,0.00073044957,0.00076767843,0.00006798022],"category_scores_gemma":[0.00029928563,0.00065740093,0.00041547802,0.000499818,0.00035846335,0.00008824354,0.0002881022,0.0022945236,0.000020387224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013208677,0.00020630949,0.0006991656,0.00045421353,0.00051021314,0.0001478442,0.0009623596,0.00028370053,0.906651,0.032142658,0.00097186473,0.05683854],"study_design_scores_gemma":[0.0012468467,0.0037845238,0.003671735,0.001324896,0.00023822454,0.005258954,0.004720439,0.0002392605,0.8356062,0.05569094,0.08678732,0.0014306526],"about_ca_topic_score_codex":0.00036781185,"about_ca_topic_score_gemma":0.00090945757,"teacher_disagreement_score":0.08581546,"about_ca_system_score_codex":0.0014290111,"about_ca_system_score_gemma":0.0014865594,"threshold_uncertainty_score":0.9995877},"labels":[],"label_agreement":null},{"id":"W4322101886","doi":"10.1016/j.ymgme.2023.107541","title":"Corrigendum to “Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing” [2021 Sep-Oct;134(1–2):117–131]","year":2023,"lang":"en","type":"erratum","venue":"Molecular Genetics and Metabolism","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Dalhousie University","funders":"","keywords":"Genetic enhancement; Fabry disease; Genome editing; Gene; Disease; Medicine; Biology; Genetics; Internal medicine; CRISPR","score_opus":0.018323240863208655,"score_gpt":0.29362493083749625,"score_spread":0.2753016899742876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322101886","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.042398747,0.9178268,0.009655299,0.0014209318,0.02323869,0.0030683964,0.0015987754,0.000106129344,0.0006862555],"genre_scores_gemma":[0.10237244,0.7693974,0.012578169,0.0034879756,0.022223905,0.0032159332,0.009764901,0.0017764292,0.07518286],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964342,0.000087187844,0.0005106337,0.0016230418,0.00046792493,0.00087701523],"domain_scores_gemma":[0.99780935,0.000013841544,0.00017829155,0.0010621011,0.000239135,0.0006973039],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031219472,0.00090996403,0.0007552306,0.00023653434,0.00019202974,0.0001427553,0.00041567392,0.00076484826,0.0000063932457],"category_scores_gemma":[0.00010991167,0.0009272035,0.0003222587,0.0001325606,0.00013664551,0.0000032696682,0.00039674755,0.00039101482,0.00000814622],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050564995,0.00034050457,0.000063278385,0.00092971255,0.0017017318,0.0002106178,0.00061204575,0.0004114174,0.20259157,0.00088474696,0.289088,0.50266075],"study_design_scores_gemma":[0.0012301562,0.00044203113,0.0031355957,0.00012278826,0.00028251682,0.00001470623,0.000068525136,0.00024567632,0.05880819,0.0003268167,0.9342234,0.0010995666],"about_ca_topic_score_codex":0.0000070444457,"about_ca_topic_score_gemma":0.000020513015,"teacher_disagreement_score":0.6451354,"about_ca_system_score_codex":0.000015936588,"about_ca_system_score_gemma":0.0001980588,"threshold_uncertainty_score":0.9993178},"labels":[],"label_agreement":null},{"id":"W4322200617","doi":"10.1101/2023.02.26.530100","title":"A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Mitacs","keywords":"Cas9; CRISPR; Nuclease; Computer science; Guide RNA; Genome editing; Cleavage (geology); Subgenomic mRNA; Artificial intelligence; Machine learning; Computational biology; Biology; DNA; Genetics","score_opus":0.026364134623869807,"score_gpt":0.2671971836966561,"score_spread":0.24083304907278633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322200617","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6920555,0.00064795616,0.30456337,0.000025509484,0.00032678532,0.00036218384,0.001825377,0.0001921659,0.0000011474058],"genre_scores_gemma":[0.9719961,0.00047147664,0.026523584,0.00006284156,0.0004812795,0.00010710541,0.00008373033,0.00024856534,0.00002530749],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99723035,0.00012675978,0.000519535,0.0012164693,0.00030687693,0.00060002296],"domain_scores_gemma":[0.99823,0.000012548264,0.00014065113,0.0011648941,0.00020829568,0.00024361997],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005771929,0.0006082035,0.0004823252,0.0001606853,0.00019824498,0.00012934337,0.00039796604,0.000591563,0.000007951205],"category_scores_gemma":[0.0000695326,0.00063786,0.0001349647,0.0002461036,0.00007204941,0.000010531129,0.00039487955,0.0006614691,0.0000065668182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047477217,0.000034504686,0.0015691653,0.00022185603,0.00014747493,0.000014452243,0.000004126166,0.42612046,0.571769,0.000017343575,0.000053430624,6.9944326e-7],"study_design_scores_gemma":[0.0010894673,0.00016042248,0.0070496276,0.0002761351,0.00029862762,1.9555753e-7,0.0000035991707,0.16506034,0.8227816,0.0000015054069,0.0020882634,0.0011901909],"about_ca_topic_score_codex":0.0004899204,"about_ca_topic_score_gemma":0.00007475476,"teacher_disagreement_score":0.2799406,"about_ca_system_score_codex":0.00009581056,"about_ca_system_score_gemma":0.0003664321,"threshold_uncertainty_score":0.99960726},"labels":[],"label_agreement":null},{"id":"W4322749624","doi":"10.1007/978-3-031-16061-5_11","title":"Genome-Editing Tools for Flax Genetic Improvement","year":2023,"lang":"en","type":"book-chapter","venue":"Compendium of plant genomes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Linum; Nutraceutical; Biotechnology; Context (archaeology); Genome editing; Biology; Genome; Bast fibre; Food science; Botany; Gene; Biochemistry","score_opus":0.018704783893385077,"score_gpt":0.2585163627306286,"score_spread":0.23981157883724352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322749624","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07922446,0.1087637,0.14893627,0.0007104312,0.021416547,0.022261018,0.082932465,0.0010399722,0.5347151],"genre_scores_gemma":[0.14005525,0.0143708335,0.01678781,0.00025861914,0.009708103,0.0004665057,0.03368019,0.0010497192,0.783623],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983916,0.000005123281,0.00051244866,0.0005305042,0.00019236472,0.0003679457],"domain_scores_gemma":[0.999019,0.000057479094,0.000244363,0.00049068226,0.000087269465,0.00010120075],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014159015,0.0003881532,0.0004568402,0.0001279282,0.00006568823,0.00003490063,0.0003805538,0.00029851464,0.000081654296],"category_scores_gemma":[0.000026732658,0.00041617698,0.00028742352,0.000017876853,0.000055234872,0.0000022382142,0.00024513697,0.00012370534,0.000032928525],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009613678,0.000027013955,0.00003515911,0.001029249,0.0008069146,0.00002656963,0.00009412617,0.0020651408,0.97218215,0.0020774456,0.0055153035,0.016044786],"study_design_scores_gemma":[0.000813012,0.0008853351,0.00059297297,0.00013829254,0.00020852665,0.000031083895,0.000068810325,0.00016115539,0.08080981,0.00077698304,0.9146064,0.00090763124],"about_ca_topic_score_codex":0.0000030761007,"about_ca_topic_score_gemma":0.000016649245,"teacher_disagreement_score":0.9090911,"about_ca_system_score_codex":0.000024731693,"about_ca_system_score_gemma":0.000078730955,"threshold_uncertainty_score":0.999829},"labels":[],"label_agreement":null},{"id":"W4322754788","doi":"10.1016/j.trac.2023.117000","title":"CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern","year":2023,"lang":"en","type":"review","venue":"TrAC Trends in Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Social Sciences and Humanities Research Council of Canada; University of Alberta","keywords":"CRISPR; Computational biology; Biology; Gene; Genetics; RNA; Mutation; Sequence (biology); Point mutation","score_opus":0.06002260385030967,"score_gpt":0.4150499523839334,"score_spread":0.3550273485336237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322754788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017799429,0.9890252,0.008421265,0.000020146377,0.00004576965,0.0002224879,0.00014584047,0.000013577997,0.0003258164],"genre_scores_gemma":[0.09226544,0.90707463,0.00015674453,0.0000016941102,0.00012466454,0.000044270837,0.000090384376,0.000028837241,0.00021330692],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920607,0.000012726694,0.00034798225,0.00024544282,0.00007267236,0.00011508157],"domain_scores_gemma":[0.99961776,0.000049255967,0.00010875625,0.00017372878,0.000030498912,0.000020006126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015289464,0.00016105208,0.00041663882,0.00005328387,0.000016974926,0.000008175745,0.00009698598,0.00027038137,0.0000020234318],"category_scores_gemma":[0.000059624967,0.00012439792,0.00014480589,0.00012703429,0.0001186471,0.000001678982,0.00005837034,0.00011280606,5.0364005e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022953513,0.000028336395,0.0000016407938,0.008712325,0.00013645113,0.0000018914803,0.000012947174,0.0000034371897,0.05519491,0.000013411315,0.000054569984,0.9358171],"study_design_scores_gemma":[0.0009578811,0.0002937999,0.0002109679,0.003807229,0.0025944174,0.00013900455,0.00011220262,0.0040496327,0.85800827,0.00012208507,0.12896924,0.00073529896],"about_ca_topic_score_codex":0.000012262864,"about_ca_topic_score_gemma":0.00001397152,"teacher_disagreement_score":0.93508184,"about_ca_system_score_codex":0.000008559809,"about_ca_system_score_gemma":0.000018723618,"threshold_uncertainty_score":0.50728},"labels":[],"label_agreement":null},{"id":"W4323295358","doi":"10.1007/s00439-023-02534-4","title":"oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids","year":2023,"lang":"en","type":"article","venue":"Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome Canada","funders":"National Human Genome Research Institute; National Institute of Mental Health; National Institutes of Health","keywords":"CRISPR; Biology; Locus (genetics); Indel; Genetics; Gene; Computational biology; Organoid; Cell type; Human genetics; Cas9; Genotype; Cell; Single-nucleotide polymorphism","score_opus":0.0412108129849455,"score_gpt":0.3678406762913937,"score_spread":0.3266298633064482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323295358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9451961,0.0003295114,0.052951332,0.00001360743,0.00030205926,0.0006439364,0.000025071717,0.00007794026,0.00046045086],"genre_scores_gemma":[0.9792273,0.00001521588,0.019247374,0.00004197299,0.0003585074,0.00004415358,0.0003643113,0.000078729776,0.00062240433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983822,0.00006981519,0.00031351607,0.00052458106,0.00023732765,0.00047255078],"domain_scores_gemma":[0.9992095,0.000016164484,0.0000803562,0.00037987044,0.00016141502,0.00015264534],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023974749,0.00026043222,0.00019375159,0.00020408812,0.00029076825,0.0000874015,0.00023030174,0.00014896983,0.000019322448],"category_scores_gemma":[0.00008384078,0.00029763317,0.000082948856,0.0006562976,0.00004243801,0.000004995111,0.00024585574,0.00014686208,0.000047532463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010899533,0.00006005324,0.0005921753,0.000105369465,0.000043378008,0.0000037601226,0.0008876198,0.032950006,0.9638307,0.00005048981,0.0013857448,0.00007980413],"study_design_scores_gemma":[0.00066702545,0.00049110875,0.005197253,0.00005437916,0.00007788258,0.000010891289,0.0020043014,0.017933782,0.971305,0.00006931309,0.0015583904,0.0006306797],"about_ca_topic_score_codex":0.000019967081,"about_ca_topic_score_gemma":0.000015365238,"teacher_disagreement_score":0.034031242,"about_ca_system_score_codex":0.000045616805,"about_ca_system_score_gemma":0.00006272342,"threshold_uncertainty_score":0.9999476},"labels":[],"label_agreement":null},{"id":"W4323349848","doi":"10.1016/j.jmb.2023.168041","title":"Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type II Anti-CRISPR Proteins","year":2023,"lang":"en","type":"review","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Biology; Mobile genetic elements; Genome editing; Cas9; Computational biology; Trans-activating crRNA; Plasmid; CRISPR interference; Transposable element; Palindrome; Archaea; Genetics; Gene; Genome","score_opus":0.02189250775914624,"score_gpt":0.3737601008046184,"score_spread":0.35186759304547216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323349848","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017527821,0.9071611,0.08976139,0.000028874072,0.00069291366,0.00041818645,0.00012790151,0.00001051361,0.000046332018],"genre_scores_gemma":[0.0047694803,0.99260104,0.0017645152,0.00004677475,0.00024621625,0.000012562501,0.0003319262,0.00008998755,0.00013748856],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979647,0.00019978118,0.000971419,0.00035139368,0.0001849733,0.00032777232],"domain_scores_gemma":[0.9983281,0.000019473782,0.0008660905,0.00037685854,0.0002857656,0.00012374266],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043974174,0.00039635896,0.0012384364,0.00026734566,0.000054143387,0.000010293221,0.00036232808,0.00073084235,0.000025575127],"category_scores_gemma":[0.00022577122,0.000334447,0.00067970535,0.0002815708,0.00008419126,0.0000034718184,0.00031630576,0.00038079164,0.000010733372],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035713532,0.00012526587,0.0000016546946,0.0024635813,0.0008403823,0.000101857004,0.000016175023,0.000039681534,0.9226582,0.00021514039,0.003925385,0.06957698],"study_design_scores_gemma":[0.00057360926,0.0023824722,0.0000012553378,0.0019918534,0.0007842887,0.00041442603,0.000039223698,0.0000031498216,0.36644354,0.00035274978,0.62650084,0.0005125791],"about_ca_topic_score_codex":0.000007777106,"about_ca_topic_score_gemma":0.0000021075698,"teacher_disagreement_score":0.62257546,"about_ca_system_score_codex":0.000029429972,"about_ca_system_score_gemma":0.00023534188,"threshold_uncertainty_score":0.9999108},"labels":[],"label_agreement":null},{"id":"W4323352175","doi":"10.1101/2023.03.03.531057","title":"A Flexible Transgene Integration ‘Landing-Pad’ Toolkit in Human Induced Pluripotent Stem Cells Enables Facile Cellular Engineering, Gene Zygosity Control, and Parallel Transgene Integration","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Transgene; Recombinase; Biology; Induced pluripotent stem cell; Genome editing; Regenerative medicine; Computational biology; Genome engineering; Stem cell; Embryonic stem cell; Cell biology; Computer science; Genetics; Gene; Genome","score_opus":0.016210777958665275,"score_gpt":0.2349910253470672,"score_spread":0.21878024738840193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323352175","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7672165,0.0013154781,0.22958487,0.00004913686,0.0005385148,0.00089745224,0.00023622933,0.00016062813,0.000001150708],"genre_scores_gemma":[0.9959138,0.0007535782,0.002416231,0.00003477177,0.00032829377,0.00035371163,0.000018313198,0.00015502489,0.000026253849],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997061,0.00010616946,0.0007384386,0.0011841038,0.00029264943,0.0006176206],"domain_scores_gemma":[0.99858576,0.00002007169,0.00019046014,0.0007829616,0.00017971272,0.00024103069],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005389142,0.0007310163,0.0006633426,0.00036123185,0.0001243807,0.00018287956,0.0003807236,0.00084150716,0.0000071446657],"category_scores_gemma":[0.000031622007,0.0008058189,0.00020126616,0.00028765868,0.000050891405,0.00002003065,0.00015228955,0.00063136837,0.00000721787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006450743,0.00008163422,0.00056712003,0.00026721277,0.00014115208,0.000023119364,0.000042910142,0.011430772,0.98729205,0.000038817197,0.00003670724,0.000013993809],"study_design_scores_gemma":[0.0014035144,0.00018134127,0.007307314,0.00024714696,0.000106187246,7.5809126e-8,0.000015744865,0.006135138,0.98339355,0.0000016569119,0.00038703546,0.0008212803],"about_ca_topic_score_codex":0.00018335332,"about_ca_topic_score_gemma":0.00008200497,"teacher_disagreement_score":0.22869729,"about_ca_system_score_codex":0.00014313652,"about_ca_system_score_gemma":0.00016419611,"threshold_uncertainty_score":0.99943924},"labels":[],"label_agreement":null},{"id":"W4323363119","doi":"10.21203/rs.3.rs-2625838/v1","title":"PAM-Flexible Genome Editing with an Engineered Chimeric Cas9","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Cas9; Genome editing; CRISPR; Computational biology; Genome engineering; Limiting; Protein engineering; Genome; Biology; Computer science; Flexibility (engineering); Genetics; Enzyme; Gene; Engineering; Biochemistry","score_opus":0.04928726360684882,"score_gpt":0.4087015400650201,"score_spread":0.35941427645817126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323363119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96543777,0.003582615,0.026107676,0.0003234613,0.0006406107,0.0014696462,0.0003743921,0.00033109201,0.0017327166],"genre_scores_gemma":[0.9906204,0.0008160269,0.002221393,0.000013383649,0.0022400033,0.00027288464,0.001880368,0.00017368143,0.0017619049],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973326,0.00012501595,0.00023647725,0.0008687598,0.00061031914,0.00082685205],"domain_scores_gemma":[0.998228,0.000032188054,0.000047930225,0.00107734,0.0003280312,0.0002865126],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007653268,0.0003207973,0.00027190647,0.0003129956,0.0001555432,0.0001281622,0.0005352427,0.0003813006,0.0000403755],"category_scores_gemma":[0.00016301616,0.00030416032,0.0001087832,0.00036456125,0.00009206847,0.000003506779,0.0009259016,0.00091112923,0.000051228744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047753975,0.00039565534,0.0038278624,0.0046830275,0.00095854345,0.0005207334,0.0013611156,0.33214843,0.6409442,0.00012340292,0.0055726008,0.008986895],"study_design_scores_gemma":[0.00443206,0.01078757,0.09745117,0.0027823104,0.0002317768,0.0003288248,0.006891914,0.025097903,0.6339462,0.00096598506,0.21079768,0.006286642],"about_ca_topic_score_codex":0.0002159784,"about_ca_topic_score_gemma":0.0001331302,"teacher_disagreement_score":0.30705053,"about_ca_system_score_codex":0.000052479816,"about_ca_system_score_gemma":0.0002709434,"threshold_uncertainty_score":0.99994105},"labels":[],"label_agreement":null},{"id":"W4323364288","doi":"10.26434/chemrxiv-2023-qhhkz","title":"Disrupting Protein Expression with Double-Clicked sgRNA-Cas9 Complexes: A Modular Approach to CRISPR Gene Editing","year":2023,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cas9; Guide RNA; CRISPR; Subgenomic mRNA; Genome editing; Nucleotide; RNA; Computational biology; Biology; Gene; Genetics","score_opus":0.03215286005047145,"score_gpt":0.30914700388014277,"score_spread":0.2769941438296713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323364288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8152685,0.00040019455,0.18164767,0.00010713224,0.0002567874,0.0012520537,0.000017428189,0.00015981428,0.0008904299],"genre_scores_gemma":[0.9515456,0.000026324438,0.043733213,0.00005772416,0.001654026,0.00091706804,0.0008111671,0.00020323251,0.0010516624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99724203,0.000035008616,0.00044258914,0.0013020178,0.00034517783,0.00063317193],"domain_scores_gemma":[0.9982632,0.000009614602,0.00018356451,0.0011315506,0.00014337961,0.00026872824],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030418378,0.00057680404,0.00047415448,0.00012036361,0.0001489806,0.000119542376,0.000584947,0.00046386357,0.0000072178627],"category_scores_gemma":[0.00006645683,0.00053703063,0.00018863064,0.00018406597,0.00006226068,0.000004052629,0.001330142,0.0005036475,0.000020555344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000113481656,0.00007262601,0.00020009153,0.00056132744,0.00009766918,0.000011591361,0.0002573945,0.026693609,0.97100675,0.000011183961,0.00081623986,0.00015805877],"study_design_scores_gemma":[0.00082422886,0.00009158991,0.00026597825,0.00045494965,0.000044040153,0.000018695571,0.00033005947,0.0018706676,0.9930933,0.000032983226,0.002258413,0.00071508],"about_ca_topic_score_codex":0.000059722483,"about_ca_topic_score_gemma":0.00000924312,"teacher_disagreement_score":0.13791446,"about_ca_system_score_codex":0.000040357816,"about_ca_system_score_gemma":0.000082911494,"threshold_uncertainty_score":0.9997081},"labels":[],"label_agreement":null},{"id":"W4323519613","doi":"10.2139/ssrn.4375726","title":"Somatic Genome Editing Governance Approaches and Regulatory Capacity in Different Countries","year":2023,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Corporate governance; Genome; Somatic cell; Genome editing; Biology; Computational biology; Genetics; Political science; Business; Gene","score_opus":0.0116427683548017,"score_gpt":0.22620777047636795,"score_spread":0.21456500212156626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323519613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925698,0.005020313,0.0019752204,0.00021056688,0.00008355512,0.0000619769,0.0000032100309,0.000010932931,0.00006441594],"genre_scores_gemma":[0.99437,0.0049023773,0.000030780637,0.0000139190615,0.0003942776,0.0000062740937,0.0000077915965,0.000015962933,0.0002586624],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986808,0.0000247828,0.00016050873,0.00016114688,0.00011370936,0.0008590859],"domain_scores_gemma":[0.9997728,0.000008814757,0.000055108605,0.00010821597,0.000012328968,0.000042751395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004908881,0.00011637934,0.00011876553,0.00003782104,0.00007213157,0.00002377972,0.00009711326,0.00006622726,0.0000019758731],"category_scores_gemma":[0.000037243,0.000103917504,0.000038097412,0.00006613377,0.000038345304,0.0000045295515,0.00005005169,0.00036749485,0.000002265187],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016727336,0.00017701692,0.15030248,0.00050007395,0.0007242053,0.000028217175,0.002146755,0.011642025,0.7674298,0.040334858,0.00034763338,0.026199603],"study_design_scores_gemma":[0.0032613564,0.0008019482,0.86149174,0.00017468804,0.00007932901,0.0011215265,0.005381903,0.0049114632,0.072547615,0.041722525,0.0072644614,0.0012414196],"about_ca_topic_score_codex":0.0000070820693,"about_ca_topic_score_gemma":0.0002903644,"teacher_disagreement_score":0.71118927,"about_ca_system_score_codex":0.00010645984,"about_ca_system_score_gemma":0.00012783303,"threshold_uncertainty_score":0.42376328},"labels":[],"label_agreement":null},{"id":"W4323660293","doi":"10.1038/s41587-023-01707-w","title":"Tuning plant phenotypes by precise, graded downregulation of gene expression","year":2023,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Phenotype; Downregulation and upregulation; Gene expression; Gene; Biology; Genetics; Expression (computer science); Computational biology; Cell biology; Computer science","score_opus":0.004354769088766538,"score_gpt":0.25886439468678807,"score_spread":0.25450962559802154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323660293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851708,0.0038484945,0.009970249,0.00032690744,0.00022111533,0.00014839205,0.00006857759,0.00014074432,0.00010476305],"genre_scores_gemma":[0.9966252,0.0003407023,0.0022077824,0.00002269084,0.00007383756,0.000009022333,0.00049639394,0.000017403849,0.00020697164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931574,0.00001289956,0.00014148373,0.00025981409,0.00009000136,0.00018005128],"domain_scores_gemma":[0.99958813,0.000009945572,0.000054815417,0.0002939994,0.00002705683,0.000026051839],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080567566,0.00011021176,0.000120295874,0.000116352014,0.00003368173,0.00000367724,0.00017220626,0.0009176326,0.000005711766],"category_scores_gemma":[0.00007550898,0.00010249168,0.000041915482,0.00022008507,0.000049534756,0.0000016997121,0.00008947165,0.00020694028,0.0000039225515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026114423,0.000011412595,0.000111127054,0.000014249021,0.00001529293,0.0000011164885,0.000013495002,0.00019546863,0.9911969,0.00012493886,0.006038207,0.0022516893],"study_design_scores_gemma":[0.0002243745,0.0000825612,0.0009026148,0.000013858541,0.0000067267406,0.0000073529636,0.000024355762,0.00023435739,0.9790172,0.00009507261,0.019283112,0.000108439286],"about_ca_topic_score_codex":0.0000025322136,"about_ca_topic_score_gemma":0.0000030794665,"teacher_disagreement_score":0.013244905,"about_ca_system_score_codex":0.000005197255,"about_ca_system_score_gemma":0.000012046106,"threshold_uncertainty_score":0.7077623},"labels":[],"label_agreement":null},{"id":"W4324307167","doi":"10.1007/978-981-99-0113-5_4","title":"Pseudotyped Viruses for Retroviruses","year":2023,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Jewish General Hospital","funders":"","keywords":"Retrovirus; Genome; Biology; Genetic enhancement; Vector (molecular biology); Computational biology; Viral vector; Gene; Virology; Genetics","score_opus":0.03425056699852652,"score_gpt":0.44385940316743255,"score_spread":0.40960883616890603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324307167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95367503,0.04328513,0.0011749386,0.00016785988,0.0004158033,0.0002212701,0.000010012366,0.00003001649,0.0010199209],"genre_scores_gemma":[0.9952777,0.003401525,0.00039047134,0.00037713745,0.0002869892,0.00007199572,0.00005988895,0.000010675232,0.00012361824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999442,0.000012254781,0.00012807133,0.00022129797,0.00002265557,0.0001737509],"domain_scores_gemma":[0.9998055,0.000037092163,0.000020488576,0.000094313145,0.000009135437,0.000033486835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083126455,0.00009301089,0.0001247486,0.0000626214,0.00002907097,0.0000017320133,0.000061909355,0.00006472401,0.000017209042],"category_scores_gemma":[0.00007883048,0.00007424863,0.000018888375,0.00007553754,0.00012445058,0.0000033874232,0.000048573194,0.000029443738,0.000004047785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010506324,0.000013158104,0.0047646286,0.000014497097,0.00000702829,9.267929e-7,0.000075168944,0.000020633131,0.9868706,0.0003589632,0.0006751308,0.0070941956],"study_design_scores_gemma":[0.0011718269,0.0017420446,0.0007960059,0.000021511452,0.0000044305134,0.000007927317,0.00079299044,0.000068965404,0.58662677,0.00035657783,0.4082582,0.00015274422],"about_ca_topic_score_codex":0.0000092030095,"about_ca_topic_score_gemma":0.000016184924,"teacher_disagreement_score":0.4075831,"about_ca_system_score_codex":0.0000042628817,"about_ca_system_score_gemma":0.000005533643,"threshold_uncertainty_score":0.3027771},"labels":[],"label_agreement":null},{"id":"W4327546647","doi":"10.1016/j.repbio.2023.100755","title":"Suitability of a universal electroporation device for genome editing and production of transgenic rats","year":2023,"lang":"en","type":"article","venue":"Reproductive Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Razi Vaccine and Serum Research Institute; Iran National Science Foundation","keywords":"mCherry; Electroporation; Genome editing; Zygote; Transgenesis; Biology; Green fluorescent protein; CRISPR; Embryo; Transgene; Cas9; Reporter gene; Reproductive technology; Blastocyst; Molecular biology; Cell biology; Gene; Genetics; Gene expression; Embryogenesis","score_opus":0.013745240640736978,"score_gpt":0.31863202801903046,"score_spread":0.3048867873782935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327546647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99423426,0.0005649707,0.0045352136,0.00018021122,0.0001418562,0.00029729103,0.000019611789,0.000010360261,0.000016205797],"genre_scores_gemma":[0.9987002,0.00015626181,0.0005646744,0.0000020780788,0.00033121608,0.000015301284,0.00017054175,0.000008113729,0.000051614446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930066,0.000036065296,0.00015451986,0.00036115144,0.00002638398,0.00012120327],"domain_scores_gemma":[0.9995573,0.0000121111525,0.000070029724,0.00019383355,0.00015123075,0.000015487285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035760197,0.00006847378,0.00012531043,0.00004864876,0.000025484862,0.0000010091991,0.000042692078,0.00006947134,0.0000010936459],"category_scores_gemma":[0.00028980256,0.000068873516,0.000038842707,0.00013088768,0.00008895883,0.0000028345808,0.000023034761,0.000028602617,1.8443117e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009304371,0.000014639344,0.0019461195,0.00007663153,0.00003821185,3.4614885e-8,0.00014877196,0.00021808174,0.9958784,0.00012316194,0.00002462927,0.0014382986],"study_design_scores_gemma":[0.00014816866,0.00041183116,0.011307031,0.0000025477416,0.000018532222,0.0000025900501,0.00022024517,0.000038226142,0.98601747,0.00029990257,0.0014696011,0.00006386611],"about_ca_topic_score_codex":0.0000090076865,"about_ca_topic_score_gemma":0.000013137868,"teacher_disagreement_score":0.009860918,"about_ca_system_score_codex":0.000007718033,"about_ca_system_score_gemma":0.000030817337,"threshold_uncertainty_score":0.28085804},"labels":[],"label_agreement":null},{"id":"W4327677487","doi":"10.1093/nar/gkad172","title":"Excessive transcription-replication conflicts are a vulnerability of <i>BRCA1</i>-mutant cancers","year":2023,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Department of Medical Biophysics, University of Toronto; Canadian Institutes of Health Research; Terry Fox Foundation; University of Birmingham; Generalitat de Catalunya; Cancer Research UK; University of Toronto; Canadian Cancer Society; Centres de Recerca de Catalunya; Government of Ontario; Cancer Research Society; European Regional Development Fund; Princess Margaret Cancer Foundation; Samuel Waxman Cancer Research Foundation","keywords":"Biology; CRISPR; Transcription (linguistics); RNA polymerase II; Genetics; Cell biology; Mutant; Transcription factor; Cancer research; Gene; Promoter; Gene expression","score_opus":0.05049404743878888,"score_gpt":0.3971324716392961,"score_spread":0.3466384242005072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327677487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966963,0.00035261622,0.0010096607,0.00037423667,0.000085373125,0.0002842208,0.000050644667,0.000030424622,0.0011165342],"genre_scores_gemma":[0.9986558,0.00041600832,0.00009419977,0.000027890479,0.00012248787,0.00008173227,0.00007240038,0.000022777249,0.00050673663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856174,0.00009791652,0.00020856403,0.00042517632,0.0003618986,0.00034471956],"domain_scores_gemma":[0.998855,0.00003365946,0.00004090817,0.00065823435,0.00031142676,0.00010075422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008431436,0.000100635225,0.00013871152,0.00010988634,0.00010450865,0.000016487369,0.00026557388,0.00013121776,0.00004751814],"category_scores_gemma":[0.0003003224,0.00009920446,0.0000710396,0.00048266482,0.0001742079,0.0000039187644,0.00008784126,0.0001866066,0.000025699524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058456182,0.000022303246,0.0023078015,0.00008102617,0.000027563112,0.0000021919511,0.00030696508,0.0008431532,0.9914231,0.000060091963,0.0014432883,0.0034241015],"study_design_scores_gemma":[0.000478566,0.00021154914,0.04365192,0.00003550865,0.0000069171933,0.0000034153431,0.0006716919,0.0015666469,0.9162076,0.00012273884,0.03689717,0.00014628885],"about_ca_topic_score_codex":0.00011805049,"about_ca_topic_score_gemma":0.000065585824,"teacher_disagreement_score":0.075215474,"about_ca_system_score_codex":0.00004626565,"about_ca_system_score_gemma":0.000105616295,"threshold_uncertainty_score":0.40454406},"labels":[],"label_agreement":null},{"id":"W4327744893","doi":"10.1038/s41467-023-36874-6","title":"CRISPR-induced DNA reorganization for multiplexed nucleic acid detection","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Toronto","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs; Government of Canada; Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation","keywords":"CRISPR; Nucleic acid; Computational biology; RNA; Biology; DNA; Genetics; Gene","score_opus":0.016243506645590735,"score_gpt":0.33644306558086456,"score_spread":0.32019955893527385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327744893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94844604,0.0029009567,0.042423118,0.0029168942,0.0009505689,0.0010994809,0.00008329764,0.00041185154,0.0007678114],"genre_scores_gemma":[0.99524295,0.00025159042,0.003336111,0.000120564866,0.00012908601,0.00008618117,0.0006733856,0.000033045882,0.00012707202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947613,0.00002944086,0.0001254535,0.00016959092,0.000059276834,0.00014007888],"domain_scores_gemma":[0.99884605,0.000031210482,0.00003745843,0.00089960627,0.00014774626,0.000037942933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293565,0.00008972703,0.000067544635,0.00006838444,0.00021797286,0.00001945501,0.0003661235,0.00026969102,0.0000026325824],"category_scores_gemma":[0.0003829654,0.00009898282,0.000056342218,0.00030814964,0.000019465768,0.0000034833333,0.00015736408,0.0001777465,0.000016260126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008345336,0.000015455173,0.00012472644,0.0000075433204,0.00001491731,4.7846328e-8,0.00004799849,0.0000589762,0.99505174,0.00014164258,0.001895269,0.0026333155],"study_design_scores_gemma":[0.0002968454,0.000055302044,0.0059554693,0.0000042260535,0.000017062495,0.0000024459107,0.00008297841,0.0032835295,0.92399645,0.00005009545,0.06612735,0.00012821659],"about_ca_topic_score_codex":0.0000027706844,"about_ca_topic_score_gemma":0.00020333585,"teacher_disagreement_score":0.071055286,"about_ca_system_score_codex":0.000014105568,"about_ca_system_score_gemma":0.000020611405,"threshold_uncertainty_score":0.40364024},"labels":[],"label_agreement":null},{"id":"W4353094097","doi":"10.1016/j.jmb.2023.168058","title":"Ten Years of Anti-CRISPR Research","year":2023,"lang":"en","type":"editorial","venue":"Journal of Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Computational biology; Biology; Genetics; Gene","score_opus":0.014676717243264574,"score_gpt":0.4106708796704459,"score_spread":0.39599416242718133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4353094097","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.115890995,0.010962933,0.0086733755,0.00013098598,0.8636969,0.00022798551,0.00018911088,0.0000123705195,0.00021539051],"genre_scores_gemma":[0.19338676,0.011561789,0.0030283227,0.000036573627,0.79027635,0.000013832661,0.0006083173,0.00028871628,0.00079931854],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.997784,0.00027065846,0.00068401184,0.00032047144,0.0005124883,0.0004283737],"domain_scores_gemma":[0.99782056,0.00024578682,0.0003924912,0.00046885334,0.0009518724,0.00012045626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016148777,0.0002143604,0.00058151636,0.0004312262,0.000026865817,0.000014017095,0.0007131847,0.0011629285,0.000008436124],"category_scores_gemma":[0.003232125,0.00020984636,0.00036294333,0.0002555884,0.00019599726,0.0000016416693,0.00031519515,0.00092198147,0.000011267834],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047496964,0.000027006778,0.000029317202,0.00005054215,0.00021486984,0.000072164614,0.0000138231835,0.00013295755,0.53458625,0.0000102306885,0.46373114,0.0010841826],"study_design_scores_gemma":[0.0005559521,0.0011846805,0.000119554774,0.00009932205,0.00006284361,0.000023175622,0.000034666704,0.000003323495,0.19536449,0.00016886994,0.8021762,0.00020691007],"about_ca_topic_score_codex":0.0000243107,"about_ca_topic_score_gemma":0.0000062001486,"teacher_disagreement_score":0.33922178,"about_ca_system_score_codex":0.000025491341,"about_ca_system_score_gemma":0.00046722998,"threshold_uncertainty_score":0.896957},"labels":[],"label_agreement":null},{"id":"W435493733","doi":"10.1111/cag.12164","title":"Growing resistance: Canadian farmers and the politics of genetically modified wheat","year":2015,"lang":"en","type":"article","venue":"Canadian Geographies / Géographies canadiennes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Politics; Resistance (ecology); Citation; Genetically engineered; Political science; Genetically modified organism; Biotechnology; Sociology; Genetics; Law; Biology; Agronomy; Gene","score_opus":0.006684181144621801,"score_gpt":0.213677234382581,"score_spread":0.2069930532379592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W435493733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97147757,0.018695837,0.0000610634,0.0019878834,0.0004135973,0.00035936412,0.0002000648,0.000015230579,0.006789367],"genre_scores_gemma":[0.9965881,0.0015824037,0.00031774188,0.00076063,0.00014239628,0.00003571982,0.00007106958,0.000041339732,0.0004605838],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99810016,0.00006821384,0.0003263118,0.00039199417,0.00016731773,0.0009460202],"domain_scores_gemma":[0.99742264,0.000036086414,0.000056723224,0.0005249969,0.00023816239,0.0017214138],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033882135,0.00029279088,0.00030089146,0.0010434677,0.00033755775,0.00005682634,0.00037144538,0.00019593729,0.000005691462],"category_scores_gemma":[0.00018801197,0.0002616036,0.00016785553,0.00096669147,0.0016805724,0.000009962989,0.000048602302,0.0001390329,5.930573e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011414867,0.000097226504,0.29057732,0.0010175495,0.004392322,0.00043613554,0.015870867,0.007858086,0.014952482,0.47510728,0.16516614,0.023383118],"study_design_scores_gemma":[0.008382859,0.0007253125,0.065309525,0.00022813317,0.00063523697,0.0002921473,0.047962174,0.00041914123,0.0066052354,0.01145975,0.8547728,0.0032076908],"about_ca_topic_score_codex":0.8328606,"about_ca_topic_score_gemma":0.9960807,"teacher_disagreement_score":0.68960667,"about_ca_system_score_codex":0.000045563836,"about_ca_system_score_gemma":0.0005968314,"threshold_uncertainty_score":0.9999836},"labels":[],"label_agreement":null},{"id":"W4360962726","doi":"10.26443/msurj.v18i1.195","title":"Uncovering the Regulators of CRISPR-Cas Immunity","year":2023,"lang":"en","type":"article","venue":"McGill Science Undergraduate Research Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Biology; Genome editing; Quorum sensing; Computational biology; CRISPR interference; Gene; Genome; Archaea; Regulator; Trans-activating crRNA; Organism; Acquired immune system; Genetics; Immune system; Biofilm; Bacteria","score_opus":0.04235499986403939,"score_gpt":0.4037570961370827,"score_spread":0.3614020962730433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360962726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918122,0.00028625308,0.0020968416,0.0030473461,0.00032384277,0.000134744,0.000007134082,0.000015264295,0.0022763417],"genre_scores_gemma":[0.9979015,0.0013506052,0.00015435582,0.000018138433,0.00010840431,0.000003837751,0.0000017850216,0.000012828829,0.00044854265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977682,0.00014511513,0.00022971157,0.0002223102,0.0009862821,0.0006483616],"domain_scores_gemma":[0.9988228,0.000068321664,0.000058092966,0.00043313517,0.00043601444,0.00018161174],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0054322807,0.00009556168,0.000097397424,0.00029457547,0.0013267226,0.00008675913,0.0008670637,0.00004565952,0.00000605317],"category_scores_gemma":[0.00085145124,0.00006623443,0.000084183856,0.0016600383,0.0007656276,0.0000144251,0.00052704616,0.00040554456,0.000014876642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001803198,0.000017878167,0.0005433873,0.000012627685,0.00002064386,0.000008619421,0.000057008507,0.0072540683,0.9824028,0.0008618346,0.0019790549,0.0068240343],"study_design_scores_gemma":[0.0002446907,0.00023642016,0.0074503003,0.00003452258,0.000004724783,0.00014424768,0.0006936381,0.00090378337,0.95298165,0.006597995,0.030573742,0.00013427123],"about_ca_topic_score_codex":0.000056652745,"about_ca_topic_score_gemma":0.000028347331,"teacher_disagreement_score":0.029421147,"about_ca_system_score_codex":0.000060914597,"about_ca_system_score_gemma":0.00022313016,"threshold_uncertainty_score":0.9999734},"labels":[],"label_agreement":null},{"id":"W4361222760","doi":"10.1016/j.tig.2023.02.010","title":"Synthetic gene drives as an anthropogenic evolutionary force","year":2023,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Natural selection; Evolutionary biology; Selection (genetic algorithm); Genetics; Computer science; Artificial intelligence","score_opus":0.03519777095465559,"score_gpt":0.39936380495281437,"score_spread":0.3641660339981588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361222760","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001239853,0.99707276,0.00035556286,0.000008723225,0.0005003143,0.00025138093,0.00012447417,0.000060525632,0.00038643565],"genre_scores_gemma":[0.000794101,0.9914316,0.0014530107,0.000013709937,0.0005805968,0.00010800274,0.0014631222,0.00020656266,0.003949284],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974834,0.00012983932,0.00065712666,0.0009252579,0.00023073699,0.0005736946],"domain_scores_gemma":[0.99851424,0.000027776146,0.00014388468,0.0010988048,0.000038461538,0.00017685031],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016869936,0.00058340264,0.0008440826,0.00045650726,0.00007508415,0.000029754836,0.0005954529,0.0006371549,0.00008242089],"category_scores_gemma":[0.00003987119,0.00059044646,0.00043122127,0.0005650341,0.0001487414,0.000002600388,0.0003037654,0.00027464033,0.00010643742],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008712984,0.000101130856,0.000024710702,0.0013911693,0.00020308135,0.000044704822,0.000045526624,0.0011916839,0.0006827979,0.000030723368,0.0005903504,0.9956854],"study_design_scores_gemma":[0.00028866125,0.0004465775,0.00014139575,0.0010448063,0.00040953932,0.00020610802,0.00003907285,0.00029927108,0.0010551295,0.0000996637,0.99494934,0.0010204413],"about_ca_topic_score_codex":0.000012808583,"about_ca_topic_score_gemma":0.00007245218,"teacher_disagreement_score":0.99466497,"about_ca_system_score_codex":0.000059119502,"about_ca_system_score_gemma":0.00018844509,"threshold_uncertainty_score":0.9996547},"labels":[],"label_agreement":null},{"id":"W4361269692","doi":"10.1021/acs.jproteome.2c00790","title":"CRISPRi-Mediated Silencing of <i>Burkholderia</i> O-Linked Glycosylation Systems Enables the Depletion of Glycosylation Yet Results in Modest Proteome Impacts","year":2023,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Institute of Infection and Immunity; Australian Research Council","keywords":"Glycosylation; Burkholderia; Biology; Proteome; N-linked glycosylation; Burkholderia cenocepacia; Burkholderia cepacia complex; Gene silencing; Cell biology; Glycan; Microbiology; Biochemistry; Genetics; Glycoprotein; Gene; Bacteria","score_opus":0.049790843815504054,"score_gpt":0.3831468336019912,"score_spread":0.3333559897864872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361269692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99455476,0.0007725303,0.0032405814,0.0002613744,0.0001230157,0.0009543301,0.00003499354,0.0000060144635,0.000052419895],"genre_scores_gemma":[0.9986501,0.0006934779,0.00031282613,0.0000022635932,0.00019219736,0.000040454794,0.000050916915,0.00002264862,0.00003513359],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974087,0.00035646214,0.00091797346,0.00018598157,0.0007790019,0.000351892],"domain_scores_gemma":[0.9981591,0.0002142188,0.00043444242,0.00030272873,0.00080649287,0.000082986306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0054270998,0.00012275288,0.0002698706,0.0005079459,0.00006430536,0.000031948726,0.00028814303,0.00017705678,0.0000030648528],"category_scores_gemma":[0.0028375417,0.00009157554,0.00009119699,0.0009246753,0.00006576691,0.000021901682,0.000104152954,0.00036956547,0.000003253284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005848735,0.00004317609,0.0009240675,0.00029213968,0.000031299085,0.0000067518968,0.0003253344,0.036825266,0.9605674,0.0000079849515,0.00020236326,0.0001893536],"study_design_scores_gemma":[0.0015412788,0.0010176016,0.02391066,0.00062210625,0.000010336336,0.00002820643,0.0005933589,0.020639116,0.9510879,0.00010555401,0.0003154573,0.00012840223],"about_ca_topic_score_codex":0.00028668568,"about_ca_topic_score_gemma":0.000043139036,"teacher_disagreement_score":0.022986593,"about_ca_system_score_codex":0.00006538316,"about_ca_system_score_gemma":0.00027126624,"threshold_uncertainty_score":0.37343422},"labels":[],"label_agreement":null},{"id":"W4361303133","doi":"10.1007/978-1-0716-2990-1_3","title":"Genetic and Molecular Quality Control of Genetically Engineered Mice","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"","keywords":"Allele; Genetically modified organism; Biology; Genetically engineered; Transgene; Genetics; Phenotype; Computational biology; Disease; Human disease; Gene; Function (biology); Medicine; Pathology","score_opus":0.013881420057596922,"score_gpt":0.41366662933987774,"score_spread":0.39978520928228084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361303133","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3937691,0.0024497253,0.60332596,0.000073497526,0.00009431406,0.00016202917,0.000013718963,0.000016819458,0.00009483341],"genre_scores_gemma":[0.6417494,0.00025392286,0.357678,0.00017294458,0.000029498555,0.000037692836,0.000025747344,0.000031286778,0.000021533006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978682,0.0006293964,0.0004913861,0.00051533344,0.00008629578,0.00040943257],"domain_scores_gemma":[0.99919075,0.00012294784,0.00007548097,0.00044527985,0.00006700702,0.00009854609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010181076,0.00022923299,0.00038955954,0.0001846392,0.000018918754,0.000007141898,0.00023434406,0.0003032496,0.000008521262],"category_scores_gemma":[0.0006873796,0.00024114091,0.00011481212,0.00031097396,0.00016245115,0.0000011112468,0.0001681781,0.00013277796,0.0000025196123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034920417,0.000020667469,0.0027450302,0.000048517177,0.00006693803,0.000014930606,0.000025820964,0.0028832885,0.9833054,0.00087676605,0.0000113275055,0.009966388],"study_design_scores_gemma":[0.0010746296,0.00024634722,0.015362756,0.000012032643,0.000030195528,0.000018324803,0.000029184182,0.0024943366,0.9772119,0.0016527494,0.0015557858,0.00031175188],"about_ca_topic_score_codex":0.00002451897,"about_ca_topic_score_gemma":0.0000060351736,"teacher_disagreement_score":0.24798031,"about_ca_system_score_codex":0.000007662014,"about_ca_system_score_gemma":0.000037531365,"threshold_uncertainty_score":0.9833441},"labels":[],"label_agreement":null},{"id":"W4362422890","doi":"10.1101/2023.03.29.534844","title":"Similar deamination activity but different phenotypic outcomes induced by APOBEC3 enzymes in breast epithelial cells","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"Deamination; In vitro; Biology; Mutagenesis; Enzyme; Biochemistry; Cell; Cell culture; Molecular biology; Chemistry; Genetics; Mutation; Gene","score_opus":0.01078741469052229,"score_gpt":0.24615141650085137,"score_spread":0.23536400181032907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362422890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99197525,0.0005013554,0.004684551,0.00021432145,0.0011810135,0.0005364502,0.0007691825,0.00013619059,0.0000016699053],"genre_scores_gemma":[0.9986904,0.00030543792,0.00025655265,0.000055443903,0.00033148204,0.00017522162,0.0000039317692,0.00015633603,0.000025187372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975551,0.00012441969,0.00041621717,0.0010348819,0.00030553847,0.00056389265],"domain_scores_gemma":[0.99847895,0.000037594364,0.00020679281,0.0009509817,0.0001412324,0.00018447608],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031267724,0.00062823354,0.0005464218,0.00020802613,0.0000757326,0.00009627954,0.00046373138,0.0007508186,0.000010302518],"category_scores_gemma":[0.00009461664,0.0006632888,0.00018960427,0.00019260087,0.00004998128,0.000008672322,0.00056836946,0.0005569036,0.000021830805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034389595,0.00016488749,0.0063771084,0.0001702917,0.000111230635,0.000007338126,0.0000055204464,0.00031625564,0.99258345,0.000017743494,0.00019634614,0.000015422549],"study_design_scores_gemma":[0.00044602665,0.000037957627,0.23468462,0.000061607185,0.000039548046,1.0469301e-8,0.0000024650233,0.0003031226,0.7635752,0.0000010517671,0.00030909572,0.0005392952],"about_ca_topic_score_codex":0.00013753652,"about_ca_topic_score_gemma":0.00002958213,"teacher_disagreement_score":0.22900827,"about_ca_system_score_codex":0.00014207217,"about_ca_system_score_gemma":0.00016604867,"threshold_uncertainty_score":0.9995818},"labels":[],"label_agreement":null},{"id":"W4362464766","doi":"10.47287/cen-10108-buscon15","title":"AstraZeneca ups rare disease research in Canada","year":2023,"lang":"en","type":"article","venue":"Chemical & Engineering News","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Business; Engineering","score_opus":0.018161027145851657,"score_gpt":0.3107451059676985,"score_spread":0.29258407882184684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362464766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998268,0.0004934169,0.0004854816,0.0002585758,0.00017394107,0.000107044776,0.000017434208,0.00003817853,0.00015793234],"genre_scores_gemma":[0.9991007,0.00007838155,0.00022591384,0.00002948218,0.00022050671,0.000039879735,0.00012115403,0.000033981687,0.00015000139],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988543,0.0000098631435,0.00015719865,0.00030010875,0.0001986469,0.00047992033],"domain_scores_gemma":[0.99941105,0.000030164005,0.000008040266,0.00029525615,0.000027137394,0.00022835085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011156099,0.00013063914,0.000110967405,0.000080931524,0.000018124083,0.0000130282615,0.00020347077,0.0000654089,0.000011399256],"category_scores_gemma":[0.00013923687,0.00014423707,0.000041094685,0.000379658,0.000014052433,0.000001925791,0.00013516622,0.00020247277,0.000013689259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020509899,0.000011060037,0.0037654466,0.00008788106,0.000011738035,0.00007653657,0.000016394235,0.052516017,0.93351066,0.000030114306,0.008333816,0.0016198277],"study_design_scores_gemma":[0.00071729935,0.00003294875,0.024292976,0.0001191251,0.000007701002,0.000009424952,0.00013358468,0.019050447,0.8722758,0.0000461715,0.0826905,0.000623963],"about_ca_topic_score_codex":0.026945056,"about_ca_topic_score_gemma":0.019578394,"teacher_disagreement_score":0.07435668,"about_ca_system_score_codex":0.00009729739,"about_ca_system_score_gemma":0.0002696608,"threshold_uncertainty_score":0.99831176},"labels":[],"label_agreement":null},{"id":"W4362581530","doi":"10.1016/j.healun.2023.02.072","title":"(56) A Preclinical Study of CRISPR Porcine Cell Gene Editing Combined with IL-10 Gene Delivery for Donor Lung Immunomodulation","year":2023,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Toronto General Hospital","funders":"","keywords":"Biology; Genome editing; Gene; Molecular biology; Guide RNA; Plasmid; Complementary DNA; CRISPR; Cas9; Transfection; Gene expression; Gene delivery; Genetic enhancement; Expression vector; Genetics; Recombinant DNA","score_opus":0.010618753227842554,"score_gpt":0.3008416828993441,"score_spread":0.29022292967150154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362581530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980821,0.0007065113,0.017988283,0.000087348235,0.00009539265,0.0002777056,0.000015503467,0.0000042670194,0.000003958419],"genre_scores_gemma":[0.9982811,0.00058357295,0.0008062154,0.000012481897,0.00020274534,0.0000048960082,0.00006352303,0.000012346756,0.000033097425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993554,0.000048355254,0.00030356948,0.00008312738,0.00010876937,0.000100779085],"domain_scores_gemma":[0.9995768,0.00006717845,0.000120818586,0.000084271785,0.00012106315,0.00002988972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004851067,0.00008147618,0.00014624366,0.000050458624,0.00007034051,0.000008259757,0.00005701046,0.000042246822,0.0000019300844],"category_scores_gemma":[0.000008881275,0.00005742363,0.000059549395,0.000066044704,0.000016616146,0.000007785911,0.000007631702,0.000063266525,1.5335772e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026645637,0.000087394445,0.0060658753,0.00017289362,0.00013070233,0.0000027319968,0.001035959,0.014807414,0.97454756,5.4585763e-7,0.0002998712,0.00018448065],"study_design_scores_gemma":[0.0076238937,0.0061895447,0.15899143,0.0001026125,0.0010786593,0.00015043981,0.0010923856,0.009882237,0.8145702,0.000011039405,0.000111726134,0.0001958391],"about_ca_topic_score_codex":0.000010798439,"about_ca_topic_score_gemma":0.000018371466,"teacher_disagreement_score":0.15997738,"about_ca_system_score_codex":0.0000038603685,"about_ca_system_score_gemma":0.00002260654,"threshold_uncertainty_score":0.23416677},"labels":[],"label_agreement":null},{"id":"W4362594105","doi":"10.1158/1538-7445.am2023-3938","title":"Abstract 3938: <i>In vivo</i> genome-wide CRISPR screen in pancreatic ductal adenocarcinoma defines HSPE1 as a potential oncogene by acting through G2/M cell cycle arrest","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Carcinogenesis; Cancer research; CRISPR; Cell cycle checkpoint; Cell cycle; Pancreatic cancer; Small hairpin RNA; Biology; Oncogene; Cancer; Gene knockdown; KRAS; In vivo; Cell culture; Gene; Genetics","score_opus":0.0240889135923905,"score_gpt":0.3631005337458455,"score_spread":0.339011620153455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362594105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98720944,0.009360845,0.00014148616,0.00032591223,0.00015665368,0.0003637278,0.000084625644,0.00002550012,0.0023318115],"genre_scores_gemma":[0.99434966,0.0037381353,0.00011339114,0.00007891277,0.0004025365,0.00014846555,0.00011770662,0.00006723986,0.000983948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99763834,0.00008259754,0.0003243636,0.00063624716,0.00040238968,0.0009160818],"domain_scores_gemma":[0.99926865,0.00006788093,0.000043538414,0.0003971462,0.00008304693,0.00013974545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052620657,0.0002232266,0.00024051235,0.00017843331,0.00011666342,0.000063059146,0.00038110843,0.00018926112,0.00013969769],"category_scores_gemma":[0.00012490859,0.00024133633,0.00008583952,0.0006259407,0.00009610005,0.000013281135,0.00027126577,0.0004150331,0.000070601054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000123336,0.000054823864,0.019453667,0.00010704421,0.000025527308,0.00015337276,0.00018475368,0.004155349,0.97197807,0.0000024077779,0.003450193,0.00031142822],"study_design_scores_gemma":[0.0012643386,0.00016978732,0.0644398,0.00009053481,0.000012939493,0.000010709647,0.0009602629,0.00023106846,0.92424566,0.00008053457,0.008073582,0.00042081383],"about_ca_topic_score_codex":0.0049158805,"about_ca_topic_score_gemma":0.0010923191,"teacher_disagreement_score":0.04773247,"about_ca_system_score_codex":0.00009645067,"about_ca_system_score_gemma":0.00024978895,"threshold_uncertainty_score":0.984141},"labels":[],"label_agreement":null},{"id":"W4362604513","doi":"10.1038/s41598-023-32078-6","title":"CRISPR-resolved virus-host interactions in a municipal landfill include non-specific viruses, hyper-targeted viral populations, and interviral conflicts","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Joint Genome Institute; U.S. Department of Energy","keywords":"CRISPR; Host (biology); Virology; Virus; Biology; Host factors; Computational biology; Genetics; Gene","score_opus":0.03381777910113181,"score_gpt":0.34080195887344444,"score_spread":0.3069841797723126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362604513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948783,0.00069125544,0.000681146,0.00006463478,0.0030505648,0.0002538037,0.00001925011,0.000051514427,0.00030956048],"genre_scores_gemma":[0.99774176,0.00007358513,0.0003552271,0.000053798445,0.00012759404,0.000042047042,0.00043933085,0.000028359229,0.0011383143],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99825,0.00003950597,0.00048466597,0.0006687741,0.00019670931,0.00036035277],"domain_scores_gemma":[0.9990644,0.000012399715,0.00010282062,0.0006334345,0.000067334106,0.00011964204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053306535,0.00018774666,0.00018528104,0.00030618758,0.0001968713,0.00015096468,0.00013731197,0.00008809378,0.000035968762],"category_scores_gemma":[0.00009612362,0.00019217884,0.00008048862,0.00042679254,0.0001178029,0.000018118522,0.0002942228,0.00015653577,0.00002409178],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029064879,0.00004899959,0.0104159,0.000015168759,0.000015673048,0.00009211112,0.0006632739,0.0006842602,0.9801839,0.000008279702,0.0068124025,0.0010309404],"study_design_scores_gemma":[0.00057793467,0.00009107255,0.06867668,0.000075474214,0.000017882727,0.00016832711,0.00047259667,0.0031499097,0.45051715,0.00022673272,0.47552973,0.0004965167],"about_ca_topic_score_codex":0.00033000985,"about_ca_topic_score_gemma":0.0018890944,"teacher_disagreement_score":0.5296668,"about_ca_system_score_codex":0.000024850739,"about_ca_system_score_gemma":0.000029953615,"threshold_uncertainty_score":0.7836825},"labels":[],"label_agreement":null},{"id":"W4362614644","doi":"10.1158/1940-6207.22523560","title":"Supplementary Table 4 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Oligonucleotide; Molecular biology; Allele; Table (database); Biology; Gene; Genetics; Andrology; Medicine; Computer science; Data mining","score_opus":0.00732195479191189,"score_gpt":0.2394707071259281,"score_spread":0.23214875233401622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362614644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8390643,0.0035493674,0.0034381398,0.00035694314,0.0044710054,0.0028478836,0.14525367,0.000083589446,0.0009350837],"genre_scores_gemma":[0.7484441,0.0014499153,0.0031598525,0.0006118916,0.0010222604,0.00040106394,0.2425916,0.00028663504,0.0020326744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929724,0.00049739896,0.0018665333,0.0020077215,0.00082332385,0.0018326408],"domain_scores_gemma":[0.99717426,0.00018208902,0.00039682604,0.001341731,0.00016158003,0.00074348116],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007977811,0.0014381362,0.0016841315,0.000647567,0.00022267018,0.00017612895,0.0011726017,0.0015231085,0.01991066],"category_scores_gemma":[0.00007185661,0.0014895529,0.0005448196,0.00045064942,0.00021002423,0.000030826573,0.0003339574,0.00047633215,0.000051939096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018949117,0.00009765863,0.00014615097,0.00022226099,0.00091562065,0.00040193016,0.00042331012,0.0015306323,0.8801539,0.000010618752,0.11534647,0.0005619374],"study_design_scores_gemma":[0.0058090994,0.0015006822,0.0034823108,0.00025632628,0.0007229434,0.00002587639,0.00013158092,0.00024514517,0.5437315,0.00012564092,0.44181168,0.0021572232],"about_ca_topic_score_codex":0.304713,"about_ca_topic_score_gemma":0.8358897,"teacher_disagreement_score":0.5311767,"about_ca_system_score_codex":0.0003730075,"about_ca_system_score_gemma":0.00074903935,"threshold_uncertainty_score":0.99983686},"labels":[],"label_agreement":null},{"id":"W4362614672","doi":"10.1158/1940-6207.22523575","title":"Supplementary Table 1A-B from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Table (database); Allele; Mutation; Genetics; Biology; Molecular biology; Gene; Computer science; Database","score_opus":0.0072867765787107165,"score_gpt":0.23932575174466852,"score_spread":0.2320389751659578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362614672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8400122,0.0036012272,0.0034918902,0.00037040582,0.0045510475,0.002911734,0.14402312,0.00008653956,0.00095186324],"genre_scores_gemma":[0.74936134,0.0014690125,0.0032494604,0.0006288171,0.0010482456,0.0004125864,0.24143706,0.0002950449,0.002098412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9928117,0.00051047973,0.0019059196,0.0020520072,0.0008438666,0.0018760725],"domain_scores_gemma":[0.9971034,0.00018653326,0.00040756672,0.0013723026,0.00016725496,0.0007629525],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00081783737,0.0014731579,0.0017217834,0.0006616553,0.0002299101,0.00018201857,0.0012016358,0.0015554179,0.020165456],"category_scores_gemma":[0.000071793096,0.001526255,0.0005594304,0.00046235768,0.00021640715,0.000032103664,0.00034335675,0.00049005164,0.00005342428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021279528,0.00010097826,0.00012941321,0.00022899605,0.0009386431,0.00041252447,0.00043486553,0.0017729581,0.8792212,0.000010906226,0.11594757,0.0005891445],"study_design_scores_gemma":[0.0059816577,0.001674405,0.0030325854,0.0002638222,0.0007495643,0.000027298587,0.0001397205,0.00025712457,0.53731686,0.00013028878,0.4481901,0.0022365525],"about_ca_topic_score_codex":0.2816502,"about_ca_topic_score_gemma":0.82604945,"teacher_disagreement_score":0.54439926,"about_ca_system_score_codex":0.00038432374,"about_ca_system_score_gemma":0.000767105,"threshold_uncertainty_score":0.99980175},"labels":[],"label_agreement":null},{"id":"W4362614748","doi":"10.1158/1940-6207.22523563","title":"Supplementary Table 3 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Biology; Andrology; Genetics; Molecular biology; Internal medicine; Gene; Medicine","score_opus":0.00727906365750857,"score_gpt":0.2391915898625788,"score_spread":0.23191252620507022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362614748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8384361,0.0035313931,0.0034134446,0.00035670216,0.0044936524,0.0028398205,0.14591049,0.000083319836,0.00093503564],"genre_scores_gemma":[0.74746084,0.0014556507,0.0031696071,0.00061377476,0.0010346469,0.00040262565,0.2434758,0.00028782603,0.0020992074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99297315,0.00049745187,0.0018659986,0.002007562,0.00082336634,0.0018324757],"domain_scores_gemma":[0.9971728,0.00018180667,0.00039677104,0.0013411576,0.00016403603,0.000743448],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007972662,0.0014380558,0.0016838119,0.0006473247,0.00022258103,0.00017605355,0.0011719086,0.001523005,0.020177525],"category_scores_gemma":[0.00007267547,0.0014893255,0.00054478564,0.00045069575,0.00020999386,0.000030822946,0.000333855,0.00047634402,0.000052808587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018756803,0.0000974363,0.0001456156,0.00022325377,0.0009138943,0.0004000589,0.000422175,0.0015451092,0.87951493,0.000010297973,0.115978405,0.00056123675],"study_design_scores_gemma":[0.0057345885,0.0014567936,0.0034136185,0.0002517511,0.00070712547,0.000025252548,0.00012916472,0.00024056068,0.5406804,0.00012263436,0.44511572,0.0021224178],"about_ca_topic_score_codex":0.3062359,"about_ca_topic_score_gemma":0.8354372,"teacher_disagreement_score":0.52920127,"about_ca_system_score_codex":0.00037416635,"about_ca_system_score_gemma":0.00075130496,"threshold_uncertainty_score":0.9998369},"labels":[],"label_agreement":null},{"id":"W4362614843","doi":"10.1158/1940-6207.22523566","title":"Supplementary Table 2 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Andrology; Biology; Genetics; Molecular biology; Internal medicine; Cancer research; Medicine; Gene","score_opus":0.007184997562571259,"score_gpt":0.23907805991879857,"score_spread":0.2318930623562273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362614843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83849686,0.003576234,0.0033538975,0.0003580743,0.004498914,0.0028477116,0.14583316,0.00008373821,0.00095140294],"genre_scores_gemma":[0.7439492,0.0014712844,0.0031481544,0.0006150365,0.0010386781,0.00040306483,0.24701159,0.00028792076,0.0020751136],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929741,0.00049770274,0.0018659985,0.0020070693,0.0008230685,0.0018320532],"domain_scores_gemma":[0.99717504,0.00018104682,0.00039716336,0.0013407259,0.00016259516,0.00074341364],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00079409074,0.0014378546,0.0016840016,0.0006471609,0.0002226094,0.0001760672,0.0011719813,0.0015231159,0.020274032],"category_scores_gemma":[0.00007199187,0.0014892429,0.0005447297,0.00045055113,0.00020997955,0.000030820713,0.00033401148,0.0004763349,0.00005190423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018569951,0.00009736474,0.00014165185,0.00022163792,0.00091372523,0.0004044844,0.00042207853,0.0015492822,0.8775001,0.000010485722,0.117986955,0.0005665041],"study_design_scores_gemma":[0.005723223,0.0014639089,0.0033985323,0.00025060584,0.00071279047,0.000025580774,0.00012907047,0.00023983968,0.5348066,0.00012356801,0.45099995,0.0021263612],"about_ca_topic_score_codex":0.30600578,"about_ca_topic_score_gemma":0.83533514,"teacher_disagreement_score":0.52932936,"about_ca_system_score_codex":0.00037306373,"about_ca_system_score_gemma":0.0007483119,"threshold_uncertainty_score":0.9998371},"labels":[],"label_agreement":null},{"id":"W4362614891","doi":"10.1158/1940-6207.22523569","title":"Supplementary Table 1D from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Cancer research; Molecular biology; Biology; Chemistry; Genetics; Gene","score_opus":0.0072867765787107165,"score_gpt":0.23932575174466852,"score_spread":0.2320389751659578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362614891","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8405915,0.0035783062,0.0034829015,0.00036696348,0.004513945,0.002884062,0.14355312,0.00008525792,0.00094395224],"genre_scores_gemma":[0.7496672,0.0014683433,0.0031976511,0.000624354,0.0010370598,0.00040817316,0.2412306,0.0002909549,0.00207564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99288404,0.00050499453,0.0018868912,0.0020322758,0.00083430554,0.0018574977],"domain_scores_gemma":[0.9971358,0.000184415,0.00040227608,0.0013573933,0.00016523889,0.0007548521],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00080933655,0.0014574275,0.0017046275,0.0006536473,0.00022722057,0.00017980927,0.0011880226,0.0015402088,0.019883348],"category_scores_gemma":[0.00007324283,0.0015093883,0.00055307784,0.000456016,0.00021352021,0.000031591444,0.00033909912,0.00048409178,0.00005255702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019017959,0.00009960327,0.0001357329,0.00022663237,0.000929779,0.00040830762,0.00043156964,0.0017621394,0.8804376,0.0000107829965,0.11479341,0.0005742533],"study_design_scores_gemma":[0.005862731,0.0015011213,0.0032395166,0.00025946717,0.0007343011,0.000026548902,0.00013536413,0.00025175407,0.546426,0.00012722741,0.43925288,0.0021830923],"about_ca_topic_score_codex":0.28377277,"about_ca_topic_score_gemma":0.8265701,"teacher_disagreement_score":0.5427974,"about_ca_system_score_codex":0.00037992327,"about_ca_system_score_gemma":0.00075891137,"threshold_uncertainty_score":0.99981755},"labels":[],"label_agreement":null},{"id":"W4362625114","doi":"10.1158/1940-6207.22523575.v1","title":"Supplementary Table 1A-B from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Table (database); Allele; Mutation; Genetics; Biology; Molecular biology; Gene; Computer science; Database","score_opus":0.0072867765787107165,"score_gpt":0.23932575174466852,"score_spread":0.2320389751659578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362625114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8400122,0.0036012272,0.0034918902,0.00037040582,0.0045510475,0.002911734,0.14402312,0.00008653956,0.00095186324],"genre_scores_gemma":[0.74936134,0.0014690125,0.0032494604,0.0006288171,0.0010482456,0.0004125864,0.24143706,0.0002950449,0.002098412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9928117,0.00051047973,0.0019059196,0.0020520072,0.0008438666,0.0018760725],"domain_scores_gemma":[0.9971034,0.00018653326,0.00040756672,0.0013723026,0.00016725496,0.0007629525],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00081783737,0.0014731579,0.0017217834,0.0006616553,0.0002299101,0.00018201857,0.0012016358,0.0015554179,0.020165456],"category_scores_gemma":[0.000071793096,0.001526255,0.0005594304,0.00046235768,0.00021640715,0.000032103664,0.00034335675,0.00049005164,0.00005342428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021279528,0.00010097826,0.00012941321,0.00022899605,0.0009386431,0.00041252447,0.00043486553,0.0017729581,0.8792212,0.000010906226,0.11594757,0.0005891445],"study_design_scores_gemma":[0.0059816577,0.001674405,0.0030325854,0.0002638222,0.0007495643,0.000027298587,0.0001397205,0.00025712457,0.53731686,0.00013028878,0.4481901,0.0022365525],"about_ca_topic_score_codex":0.2816502,"about_ca_topic_score_gemma":0.82604945,"teacher_disagreement_score":0.54439926,"about_ca_system_score_codex":0.00038432374,"about_ca_system_score_gemma":0.000767105,"threshold_uncertainty_score":0.99980175},"labels":[],"label_agreement":null},{"id":"W4362625446","doi":"10.1158/1940-6207.22523560.v1","title":"Supplementary Table 4 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Oligonucleotide; Molecular biology; Allele; Table (database); Biology; Gene; Genetics; Computer science; Data mining","score_opus":0.00732195479191189,"score_gpt":0.2394707071259281,"score_spread":0.23214875233401622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362625446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8390643,0.0035493674,0.0034381398,0.00035694314,0.0044710054,0.0028478836,0.14525367,0.000083589446,0.0009350837],"genre_scores_gemma":[0.7484441,0.0014499153,0.0031598525,0.0006118916,0.0010222604,0.00040106394,0.2425916,0.00028663504,0.0020326744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929724,0.00049739896,0.0018665333,0.0020077215,0.00082332385,0.0018326408],"domain_scores_gemma":[0.99717426,0.00018208902,0.00039682604,0.001341731,0.00016158003,0.00074348116],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007977811,0.0014381362,0.0016841315,0.000647567,0.00022267018,0.00017612895,0.0011726017,0.0015231085,0.01991066],"category_scores_gemma":[0.00007185661,0.0014895529,0.0005448196,0.00045064942,0.00021002423,0.000030826573,0.0003339574,0.00047633215,0.000051939096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018949117,0.00009765863,0.00014615097,0.00022226099,0.00091562065,0.00040193016,0.00042331012,0.0015306323,0.8801539,0.000010618752,0.11534647,0.0005619374],"study_design_scores_gemma":[0.0058090994,0.0015006822,0.0034823108,0.00025632628,0.0007229434,0.00002587639,0.00013158092,0.00024514517,0.5437315,0.00012564092,0.44181168,0.0021572232],"about_ca_topic_score_codex":0.304713,"about_ca_topic_score_gemma":0.8358897,"teacher_disagreement_score":0.5311767,"about_ca_system_score_codex":0.0003730075,"about_ca_system_score_gemma":0.00074903935,"threshold_uncertainty_score":0.99983686},"labels":[],"label_agreement":null},{"id":"W4362625452","doi":"10.1158/1940-6207.22523566.v1","title":"Supplementary Table 2 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Genetics; Biology; Gene","score_opus":0.007184997562571259,"score_gpt":0.23907805991879857,"score_spread":0.2318930623562273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362625452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83849686,0.003576234,0.0033538975,0.0003580743,0.004498914,0.0028477116,0.14583316,0.00008373821,0.00095140294],"genre_scores_gemma":[0.7439492,0.0014712844,0.0031481544,0.0006150365,0.0010386781,0.00040306483,0.24701159,0.00028792076,0.0020751136],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9929741,0.00049770274,0.0018659985,0.0020070693,0.0008230685,0.0018320532],"domain_scores_gemma":[0.99717504,0.00018104682,0.00039716336,0.0013407259,0.00016259516,0.00074341364],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00079409074,0.0014378546,0.0016840016,0.0006471609,0.0002226094,0.0001760672,0.0011719813,0.0015231159,0.020274032],"category_scores_gemma":[0.00007199187,0.0014892429,0.0005447297,0.00045055113,0.00020997955,0.000030820713,0.00033401148,0.0004763349,0.00005190423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018569951,0.00009736474,0.00014165185,0.00022163792,0.00091372523,0.0004044844,0.00042207853,0.0015492822,0.8775001,0.000010485722,0.117986955,0.0005665041],"study_design_scores_gemma":[0.005723223,0.0014639089,0.0033985323,0.00025060584,0.00071279047,0.000025580774,0.00012907047,0.00023983968,0.5348066,0.00012356801,0.45099995,0.0021263612],"about_ca_topic_score_codex":0.30600578,"about_ca_topic_score_gemma":0.83533514,"teacher_disagreement_score":0.52932936,"about_ca_system_score_codex":0.00037306373,"about_ca_system_score_gemma":0.0007483119,"threshold_uncertainty_score":0.9998371},"labels":[],"label_agreement":null},{"id":"W4362625783","doi":"10.1158/1940-6207.22523572.v1","title":"Supplementary Table 1C from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Biology; Genetics; Molecular biology; Internal medicine; Andrology; Medicine; Gene","score_opus":0.0072867765787107165,"score_gpt":0.23932575174466852,"score_spread":0.2320389751659578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362625783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84087986,0.0035809528,0.0035053636,0.0003666426,0.004509757,0.0028804014,0.1432508,0.00008518626,0.00094105396],"genre_scores_gemma":[0.7496282,0.0014691354,0.0032179465,0.0006247171,0.0010375957,0.0004082282,0.24126053,0.0002911216,0.0020625433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9928842,0.00050511415,0.0018868136,0.002032191,0.00083424343,0.0018574415],"domain_scores_gemma":[0.9971359,0.00018447012,0.0004022591,0.0013573456,0.0001652311,0.0007548305],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00080920063,0.0014573958,0.0017045673,0.00065354106,0.00022718923,0.00017980268,0.0011879778,0.0015401369,0.019863676],"category_scores_gemma":[0.00007324414,0.0015093518,0.00055307086,0.0004559961,0.00021342738,0.000031586187,0.00033908742,0.00048411277,0.000052552074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019032064,0.00009967637,0.00013646879,0.0002267904,0.0009319923,0.0004122489,0.00042995374,0.0017633224,0.88115835,0.00001073357,0.114066765,0.0005733568],"study_design_scores_gemma":[0.0058713807,0.0015074906,0.003245407,0.00025978222,0.00073646876,0.000026777961,0.00013542906,0.0002520326,0.5479029,0.00012737597,0.43774873,0.0021862155],"about_ca_topic_score_codex":0.28383362,"about_ca_topic_score_gemma":0.82656586,"teacher_disagreement_score":0.54273224,"about_ca_system_score_codex":0.00037990246,"about_ca_system_score_gemma":0.0007587917,"threshold_uncertainty_score":0.99981755},"labels":[],"label_agreement":null},{"id":"W4362625813","doi":"10.1158/1940-6207.22523569.v1","title":"Supplementary Table 1D from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Biology; Genetics; Transformation (genetics); Molecular biology; Ovarian cancer; Gene; Cancer","score_opus":0.0072867765787107165,"score_gpt":0.23932575174466852,"score_spread":0.2320389751659578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362625813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8405915,0.0035783062,0.0034829015,0.00036696348,0.004513945,0.002884062,0.14355312,0.00008525792,0.00094395224],"genre_scores_gemma":[0.7496672,0.0014683433,0.0031976511,0.000624354,0.0010370598,0.00040817316,0.2412306,0.0002909549,0.00207564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99288404,0.00050499453,0.0018868912,0.0020322758,0.00083430554,0.0018574977],"domain_scores_gemma":[0.9971358,0.000184415,0.00040227608,0.0013573933,0.00016523889,0.0007548521],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00080933655,0.0014574275,0.0017046275,0.0006536473,0.00022722057,0.00017980927,0.0011880226,0.0015402088,0.019883348],"category_scores_gemma":[0.00007324283,0.0015093883,0.00055307784,0.000456016,0.00021352021,0.000031591444,0.00033909912,0.00048409178,0.00005255702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019017959,0.00009960327,0.0001357329,0.00022663237,0.000929779,0.00040830762,0.00043156964,0.0017621394,0.8804376,0.0000107829965,0.11479341,0.0005742533],"study_design_scores_gemma":[0.005862731,0.0015011213,0.0032395166,0.00025946717,0.0007343011,0.000026548902,0.00013536413,0.00025175407,0.546426,0.00012722741,0.43925288,0.0021830923],"about_ca_topic_score_codex":0.28377277,"about_ca_topic_score_gemma":0.8265701,"teacher_disagreement_score":0.5427974,"about_ca_system_score_codex":0.00037992327,"about_ca_system_score_gemma":0.00075891137,"threshold_uncertainty_score":0.99981755},"labels":[],"label_agreement":null},{"id":"W4362626268","doi":"10.1158/1940-6207.22523563.v1","title":"Supplementary Table 3 from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Genetics; Biology; Gene; Andrology; Internal medicine; Medicine","score_opus":0.00727906365750857,"score_gpt":0.2391915898625788,"score_spread":0.23191252620507022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362626268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8384361,0.0035313931,0.0034134446,0.00035670216,0.0044936524,0.0028398205,0.14591049,0.000083319836,0.00093503564],"genre_scores_gemma":[0.74746084,0.0014556507,0.0031696071,0.00061377476,0.0010346469,0.00040262565,0.2434758,0.00028782603,0.0020992074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99297315,0.00049745187,0.0018659986,0.002007562,0.00082336634,0.0018324757],"domain_scores_gemma":[0.9971728,0.00018180667,0.00039677104,0.0013411576,0.00016403603,0.000743448],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007972662,0.0014380558,0.0016838119,0.0006473247,0.00022258103,0.00017605355,0.0011719086,0.001523005,0.020177525],"category_scores_gemma":[0.00007267547,0.0014893255,0.00054478564,0.00045069575,0.00020999386,0.000030822946,0.000333855,0.00047634402,0.000052808587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018756803,0.0000974363,0.0001456156,0.00022325377,0.0009138943,0.0004000589,0.000422175,0.0015451092,0.87951493,0.000010297973,0.115978405,0.00056123675],"study_design_scores_gemma":[0.0057345885,0.0014567936,0.0034136185,0.0002517511,0.00070712547,0.000025252548,0.00012916472,0.00024056068,0.5406804,0.00012263436,0.44511572,0.0021224178],"about_ca_topic_score_codex":0.3062359,"about_ca_topic_score_gemma":0.8354372,"teacher_disagreement_score":0.52920127,"about_ca_system_score_codex":0.00037416635,"about_ca_system_score_gemma":0.00075130496,"threshold_uncertainty_score":0.9998369},"labels":[],"label_agreement":null},{"id":"W4362638994","doi":"10.1158/1940-6207.22523572","title":"Supplementary Table 1C from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"supplementary-materials","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Molecular biology; Genetics; Biology; Gene","score_opus":0.0072867765787107165,"score_gpt":0.23932575174466852,"score_spread":0.2320389751659578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362638994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84087986,0.0035809528,0.0035053636,0.0003666426,0.004509757,0.0028804014,0.1432508,0.00008518626,0.00094105396],"genre_scores_gemma":[0.7496282,0.0014691354,0.0032179465,0.0006247171,0.0010375957,0.0004082282,0.24126053,0.0002911216,0.0020625433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9928842,0.00050511415,0.0018868136,0.002032191,0.00083424343,0.0018574415],"domain_scores_gemma":[0.9971359,0.00018447012,0.0004022591,0.0013573456,0.0001652311,0.0007548305],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00080920063,0.0014573958,0.0017045673,0.00065354106,0.00022718923,0.00017980268,0.0011879778,0.0015401369,0.019863676],"category_scores_gemma":[0.00007324414,0.0015093518,0.00055307086,0.0004559961,0.00021342738,0.000031586187,0.00033908742,0.00048411277,0.000052552074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019032064,0.00009967637,0.00013646879,0.0002267904,0.0009319923,0.0004122489,0.00042995374,0.0017633224,0.88115835,0.00001073357,0.114066765,0.0005733568],"study_design_scores_gemma":[0.0058713807,0.0015074906,0.003245407,0.00025978222,0.00073646876,0.000026777961,0.00013542906,0.0002520326,0.5479029,0.00012737597,0.43774873,0.0021862155],"about_ca_topic_score_codex":0.28383362,"about_ca_topic_score_gemma":0.82656586,"teacher_disagreement_score":0.54273224,"about_ca_system_score_codex":0.00037990246,"about_ca_system_score_gemma":0.0007587917,"threshold_uncertainty_score":0.99981755},"labels":[],"label_agreement":null},{"id":"W4362735936","doi":"10.3389/fcell.2023.1158373","title":"Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived cultures","year":2023,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Fondation Brain Canada; Simons Foundation; Brain and Behavior Research Foundation","keywords":"CRISPR; Induced pluripotent stem cell; Genome editing; Biology; Neuroscience; Computational biology; Genomics; Cas9; Functional genomics; Model organism; Embryonic stem cell; Genome; Gene; Genetics","score_opus":0.06797671863365597,"score_gpt":0.34076330033142893,"score_spread":0.272786581697773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362735936","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03692873,0.9583951,0.003633269,0.0000031116997,0.00037169494,0.00050060614,0.000041648273,0.000019397656,0.00010644214],"genre_scores_gemma":[0.019336548,0.9736141,0.006007621,0.000026202804,0.00007065022,0.000060881197,0.00057877897,0.000064225496,0.00024097803],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981145,0.00009167003,0.000564257,0.0006960561,0.00007429518,0.00045921025],"domain_scores_gemma":[0.99961376,0.000019078803,0.000115828785,0.00011533299,0.0000100888965,0.00012592424],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013048336,0.00045998435,0.0007983259,0.00029783012,0.0001368636,0.0000314848,0.00015912202,0.00039935537,0.0000017687582],"category_scores_gemma":[0.0000064019755,0.000412741,0.000081770326,0.00017016717,0.00012409328,0.000004765429,0.00035687519,0.00021300495,9.303875e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003168,0.0007649581,0.05663203,0.055153627,0.0016328669,0.0007050729,0.005850411,0.0007945228,0.08294751,0.00010368577,0.008612314,0.7864862],"study_design_scores_gemma":[0.0060033565,0.00058456074,0.0031430828,0.008119107,0.0006912707,0.00025964525,0.01792179,0.000677772,0.024068832,0.0002689402,0.9314392,0.0068224114],"about_ca_topic_score_codex":0.000025648083,"about_ca_topic_score_gemma":0.0000667407,"teacher_disagreement_score":0.9228269,"about_ca_system_score_codex":0.00019144235,"about_ca_system_score_gemma":0.00014426521,"threshold_uncertainty_score":0.99983245},"labels":[],"label_agreement":null},{"id":"W4365143776","doi":"10.1016/j.jbc.2023.104700","title":"Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institutes of Health; National Institute of General Medical Sciences; Indian Institute of Technology Bombay; Compute Canada","keywords":"Pseudoknot; Trans-activating crRNA; Ribonucleoprotein; RNA; Biology; Nucleic acid structure; Computational biology; CRISPR; Biophysics; Genetics; Chemistry; Cas9; Gene","score_opus":0.023908485088146088,"score_gpt":0.29783368637608154,"score_spread":0.27392520128793546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4365143776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997752,0.00037233936,0.00024960522,0.0012223783,0.00008360023,0.00008759286,0.000023749211,0.000012515345,0.0001961862],"genre_scores_gemma":[0.99854285,0.00031499614,0.00029099188,0.00011071296,0.00040751093,0.000008101312,0.000021270498,0.000008853716,0.000294735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991391,0.000032926968,0.00030170882,0.00014980862,0.0001449535,0.00023151179],"domain_scores_gemma":[0.9994605,0.000039022383,0.00014396802,0.00012731127,0.00010124701,0.00012792746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005762971,0.00013620024,0.00016916977,0.000034709457,0.00010613699,0.000043439653,0.00021184843,0.00015400544,0.000019953926],"category_scores_gemma":[0.0003419129,0.000089197034,0.00006941389,0.00012755547,0.00004871048,0.000004589077,0.00016696847,0.00015956601,0.000004638408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035433117,0.000008388755,0.00040724242,0.000030581996,0.000042242435,0.0000131824245,0.000045555407,0.00013241825,0.997615,0.000001870183,0.00079718436,0.0008709362],"study_design_scores_gemma":[0.00037707484,0.00013018031,0.010330134,0.00003645254,0.000009550942,0.00018595396,0.00036459148,0.000036636546,0.98254764,0.0000080572245,0.0058413194,0.0001324242],"about_ca_topic_score_codex":0.0000033212457,"about_ca_topic_score_gemma":0.000003541096,"teacher_disagreement_score":0.01506734,"about_ca_system_score_codex":0.000015008284,"about_ca_system_score_gemma":0.00003736239,"threshold_uncertainty_score":0.36373496},"labels":[],"label_agreement":null},{"id":"W4365399020","doi":"10.17504/protocols.io.q26g7yzz3gwz/v2","title":"HTTM : gDNA extraction v2","year":2022,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"genomic DNA; Extraction (chemistry); Transposable element; Computational biology; Biology; DNA; Genetics; Genome; Chromatography; Chemistry; Gene","score_opus":0.01018642154653812,"score_gpt":0.3369164411981117,"score_spread":0.3267300196515736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4365399020","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6583101,0.0072687604,0.22472535,0.0007099877,0.0055428017,0.0007885767,0.00010594486,0.0001955907,0.10235288],"genre_scores_gemma":[0.9792502,0.00068242475,0.0031850669,0.00020237567,0.0006501414,0.00010117391,0.0007105835,0.000046052282,0.015171987],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99916697,0.000020659278,0.00014844286,0.0003917036,0.000113751914,0.00015849549],"domain_scores_gemma":[0.9994041,0.0000039714355,0.000043914508,0.00047334904,0.000023580029,0.00005112736],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010059609,0.00016499206,0.00011293706,0.00003912362,0.000047588615,0.000022854552,0.00019085,0.00019887836,0.00092337595],"category_scores_gemma":[0.000019762194,0.00017913025,0.0001261529,0.000028619135,0.000012140511,4.6103764e-7,0.0006764227,0.00028685902,0.000011847666],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053267664,0.00011736414,0.000759211,0.00018249647,0.00021471063,0.000014189326,0.000079128,0.05662305,0.8677145,0.00017873732,0.057377547,0.016685778],"study_design_scores_gemma":[0.00018773599,0.0000964446,0.0018960724,0.000008928684,0.000034427634,0.000019872505,0.00010682384,0.0006020671,0.20128448,0.00015794652,0.79515725,0.0004479394],"about_ca_topic_score_codex":0.000052041483,"about_ca_topic_score_gemma":0.000027270897,"teacher_disagreement_score":0.7377797,"about_ca_system_score_codex":0.000019196872,"about_ca_system_score_gemma":0.0000572074,"threshold_uncertainty_score":0.9999899},"labels":[],"label_agreement":null},{"id":"W4365455345","doi":"10.1101/2023.04.12.536587","title":"Chromatin context-dependent regulation and epigenetic manipulation of prime editing","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Damon Runyon Cancer Research Foundation; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Chromatin; Prime (order theory); Epigenome; Genome editing; Computational biology; Computer science; Genome browser; Context (archaeology); Epigenetics; Set (abstract data type); Biology; Genetics; Genomics; DNA; Genome; DNA methylation; Gene; Programming language; Mathematics","score_opus":0.013602375176759466,"score_gpt":0.24978037521643873,"score_spread":0.23617800003967926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4365455345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9620536,0.0027748751,0.033785682,0.00004900256,0.00067466946,0.0004890857,0.000078852776,0.00009050898,0.000003731633],"genre_scores_gemma":[0.99645513,0.00032979788,0.0024478831,0.000015518803,0.00057595613,0.00005975934,0.0000035316677,0.000099296274,0.000013139587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983014,0.000056985937,0.00047780186,0.0006497444,0.00024157304,0.00027250583],"domain_scores_gemma":[0.99866164,0.000018616547,0.00029154445,0.0007145852,0.00020807525,0.00010555622],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040372644,0.00031342788,0.00033648242,0.00013185652,0.000062817395,0.00004902873,0.00019041802,0.00041810118,0.000007874677],"category_scores_gemma":[0.00017027509,0.00037321477,0.000101235026,0.00011505858,0.00006118188,0.0000052038004,0.00039249758,0.00019228343,0.000006599727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001076338,0.000020966449,0.0038653826,0.00033395563,0.00011275707,0.0000025228069,0.000008210509,0.0024558606,0.99306434,0.000045382476,0.00005729689,0.000022533784],"study_design_scores_gemma":[0.0002779621,0.00005831072,0.18279524,0.0001986118,0.000069464884,2.5258347e-8,0.000005312528,0.0018706749,0.814064,0.0000032203816,0.00034799177,0.00030918603],"about_ca_topic_score_codex":0.000044295437,"about_ca_topic_score_gemma":0.00000801758,"teacher_disagreement_score":0.17900038,"about_ca_system_score_codex":0.000038101338,"about_ca_system_score_gemma":0.00010392023,"threshold_uncertainty_score":0.99987197},"labels":[],"label_agreement":null},{"id":"W4366551165","doi":"10.1093/bib/bbad131","title":"Using traditional machine learning and deep learning methods for on- and off-target prediction in CRISPR/Cas9: a review","year":2023,"lang":"en","type":"review","venue":"Briefings in Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"CRISPR; Computer science; Artificial intelligence; Deep learning; Machine learning; Biology","score_opus":0.07105972471653552,"score_gpt":0.42177421743390064,"score_spread":0.3507144927173651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366551165","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000016226628,0.93948096,0.05953415,0.00002245542,0.0000759471,0.00072199345,0.000048859234,0.000021717902,0.00007767501],"genre_scores_gemma":[0.0000030158706,0.916466,0.08251354,0.00011267002,0.00007322161,0.000096314405,0.0006300831,0.000052069227,0.00005311273],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99844605,0.00010565307,0.0007816793,0.00028300172,0.000102117156,0.00028147834],"domain_scores_gemma":[0.9993318,0.00019963236,0.00025273208,0.00011931812,0.000029952522,0.00006656915],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001050684,0.0003244297,0.00077844376,0.0002299153,0.0000850206,0.00003948806,0.00008888276,0.0002944609,0.0000036921308],"category_scores_gemma":[0.00081254606,0.00031795725,0.00013474002,0.00022105228,0.00004109935,0.000009974711,0.000101287704,0.0004471481,0.0000010334735],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008272822,0.0000150082615,0.000031705513,0.04580252,0.00006349976,0.000001753585,0.00010499943,0.00068951026,0.000018030416,0.00003652436,0.00012646583,0.9531017],"study_design_scores_gemma":[0.00035842726,0.00016906757,0.0000145366885,0.016752727,0.00014490183,0.000114696326,0.000029736064,0.086729206,0.000017551394,0.00004082944,0.89529103,0.00033728086],"about_ca_topic_score_codex":0.000011585485,"about_ca_topic_score_gemma":0.000006668451,"teacher_disagreement_score":0.95276445,"about_ca_system_score_codex":0.00004042413,"about_ca_system_score_gemma":0.000060706447,"threshold_uncertainty_score":0.9999272},"labels":[],"label_agreement":null},{"id":"W4366605730","doi":"10.1101/2023.04.21.537819","title":"DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Medical Research Council","keywords":"Microphthalmia-associated transcription factor; DNA damage; Biology; Transcription factor; DNA repair; Genome instability; Cell biology; Genetics; Cancer research; Rad50; DNA; DNA-binding protein; Gene","score_opus":0.029146411069304285,"score_gpt":0.2910674737418766,"score_spread":0.2619210626725723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366605730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900235,0.0015791365,0.005638012,0.00032685953,0.0006084958,0.00089158386,0.00078759476,0.00014369359,0.0000011286478],"genre_scores_gemma":[0.9963145,0.002015362,0.00030138122,0.000045293396,0.00092157035,0.00026129128,0.000017747001,0.00011240563,0.000010403795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785244,0.00028835906,0.00044565104,0.0008662698,0.000217134,0.00033016503],"domain_scores_gemma":[0.99882686,0.000079428486,0.00022176099,0.00053811783,0.00017393415,0.00015990665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005477629,0.00045321902,0.000404991,0.0001755189,0.00021206833,0.00021307894,0.00022456786,0.0004930393,0.000020946965],"category_scores_gemma":[0.000088320005,0.00043097985,0.00011419432,0.00019008154,0.00013126277,0.000022168593,0.00025049626,0.00047975674,0.0000052196906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006236478,0.000023746394,0.0003875103,0.00012820977,0.00020498192,0.000005542728,0.000066941415,0.00010568524,0.9982718,0.0000063169005,0.00012086681,0.000054715747],"study_design_scores_gemma":[0.0010735457,0.00012915612,0.28613135,0.00019046619,0.00017088267,7.9884714e-8,0.000015590746,0.0011829084,0.70533085,5.4147e-7,0.0053738593,0.0004008016],"about_ca_topic_score_codex":0.000074900265,"about_ca_topic_score_gemma":0.000024392388,"teacher_disagreement_score":0.292941,"about_ca_system_score_codex":0.00009839793,"about_ca_system_score_gemma":0.00010767297,"threshold_uncertainty_score":0.9998142},"labels":[],"label_agreement":null},{"id":"W4366742785","doi":"10.1111/cpr.13475","title":"Genome‐wide screen for anticancer drug resistance in haploid human embryonic stem cells","year":2023,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation","keywords":"Biology; Gene; Drug resistance; Embryonic stem cell; Genetics; Genome; Drug discovery; Cancer cell; Genetic screen; Cancer; Cancer research; Phenotype; Bioinformatics","score_opus":0.01032227806540742,"score_gpt":0.27462378261091624,"score_spread":0.2643015045455088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366742785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884062,0.0007803753,0.00945065,0.00017976982,0.00010824025,0.00052576436,0.00001488643,0.000032381227,0.0005017553],"genre_scores_gemma":[0.9876694,0.00013066057,0.00038741587,0.000068451314,0.00018795597,0.00010763968,0.00019663756,0.000028137456,0.011223697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922544,0.000019990148,0.00017032928,0.0002788762,0.00007911045,0.00022624667],"domain_scores_gemma":[0.9996639,0.000011030202,0.000036001275,0.00020720215,0.000042666336,0.000039235452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021101728,0.000107262735,0.0001000189,0.00006284947,0.000074569696,0.000025835261,0.00010038767,0.00007198897,0.0000043867944],"category_scores_gemma":[0.0000075643056,0.00011811125,0.00004524795,0.00012223035,0.000015131552,0.000003975143,0.000033727247,0.00005275709,0.0000140596885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030503083,0.00001560977,0.0013299031,0.00009014312,0.0000062400536,9.701325e-7,0.00012233037,0.002820386,0.9928506,0.000024998559,0.0026194658,0.00008886385],"study_design_scores_gemma":[0.0005841873,0.00004674114,0.0055541988,0.000014090946,0.000007719391,1.9350362e-7,0.000051690236,0.0010076103,0.97344,0.000076336386,0.01903665,0.00018056335],"about_ca_topic_score_codex":0.0000031507384,"about_ca_topic_score_gemma":0.00025074338,"teacher_disagreement_score":0.019410567,"about_ca_system_score_codex":0.000019481908,"about_ca_system_score_gemma":0.000034852827,"threshold_uncertainty_score":0.4816437},"labels":[],"label_agreement":null},{"id":"W4366782348","doi":"10.1101/2023.04.21.537703","title":"A mobile CRISPRi collection enables genetic interaction studies for the essential genes of <i>Escherichia coli</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Gene knockdown; Gene; CRISPR; CRISPR interference; Genetics; RNA interference; Phenotype; Cas9; Computational biology; Mobile genetic elements; Escherichia coli; Genetic screen; Genome editing; Plasmid; RNA","score_opus":0.017137565516691104,"score_gpt":0.29037831040566986,"score_spread":0.27324074488897876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366782348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.917108,0.022488508,0.05553313,0.00006231054,0.0030717282,0.00147341,0.00016129392,0.00010035642,0.000001277357],"genre_scores_gemma":[0.9812569,0.011936088,0.0042100693,0.00004372244,0.0009296917,0.0014577636,0.0000016722495,0.00012843823,0.00003567511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982378,0.00006523361,0.00049245585,0.00066907326,0.00018976993,0.00034569445],"domain_scores_gemma":[0.99817467,0.0000825638,0.00030375918,0.0007944415,0.00057232095,0.00007224395],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029578173,0.00038676403,0.00040683086,0.00011686706,0.00018330566,0.00006511677,0.00036493913,0.0003460338,0.000003767066],"category_scores_gemma":[0.00020734502,0.0003554151,0.00024544905,0.0002625443,0.000117269614,0.0000052167375,0.0004179777,0.00022436114,0.0000038038834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000083049476,0.00005371261,0.00033551376,0.0006140215,0.0006116714,0.0000017532038,0.00002559188,0.016060786,0.9801449,0.000008934348,0.002052538,0.0000075214202],"study_design_scores_gemma":[0.00037808297,0.00021541139,0.003949597,0.00014043532,0.00028334325,2.7538128e-8,0.00006451362,0.0023516023,0.9775527,0.0000019872366,0.014672394,0.00038990384],"about_ca_topic_score_codex":0.000050613424,"about_ca_topic_score_gemma":0.000020520429,"teacher_disagreement_score":0.064148895,"about_ca_system_score_codex":0.000060171802,"about_ca_system_score_gemma":0.00024671652,"threshold_uncertainty_score":0.9998898},"labels":[],"label_agreement":null},{"id":"W4366824353","doi":"10.1038/s41587-023-01769-w","title":"Precise integration of large DNA sequences in plant genomes using PrimeRoot editors","year":2023,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Recombinase; Biology; Genome; Insert (composites); Computational biology; Genetics; Gene; DNA; Recombination","score_opus":0.0074758770356898865,"score_gpt":0.30488163284099945,"score_spread":0.2974057558053096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366824353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99504775,0.0021467053,0.0012961917,0.00021216822,0.0010465063,0.00012505054,0.000043062457,0.00004686171,0.00003568097],"genre_scores_gemma":[0.99798864,0.00040650036,0.0011092637,0.000015219357,0.00030662457,0.000005996767,0.000111371824,0.000011829261,0.000044535776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999305,0.0000144406085,0.0001638211,0.00023390443,0.000076096934,0.00020675642],"domain_scores_gemma":[0.99968475,0.000009192208,0.000048599508,0.00021328237,0.000025972071,0.000018214349],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001464367,0.00010332802,0.00013104467,0.00023518763,0.000020188807,0.0000035078458,0.00016652262,0.0008919871,0.0000036454674],"category_scores_gemma":[0.0000989473,0.00009530104,0.000038271162,0.0003491594,0.00005070138,0.0000021625663,0.000097033735,0.0002648118,0.000001991141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014498615,0.0000148960435,0.0008480887,0.000014793108,0.000012713171,0.0000040043087,0.000028547596,0.00022516772,0.9963398,0.00024210406,0.0006353919,0.001620015],"study_design_scores_gemma":[0.00018249042,0.00008194107,0.0010814962,0.000021654663,0.000005446887,0.000008489124,0.000108019434,0.0010557763,0.97938305,0.000084434636,0.01788714,0.00010003299],"about_ca_topic_score_codex":0.000008966357,"about_ca_topic_score_gemma":0.00008998836,"teacher_disagreement_score":0.017251749,"about_ca_system_score_codex":0.000013835768,"about_ca_system_score_gemma":0.000036449954,"threshold_uncertainty_score":0.68798214},"labels":[],"label_agreement":null},{"id":"W4366829167","doi":"10.3390/biomedicines11051238","title":"Increasing Specificity of Targeted DNA Methylation Editing by Non-Enzymatic CRISPR/dCas9-Based Steric Hindrance","year":2023,"lang":"en","type":"review","venue":"Biomedicines","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Faculty of Medicine and Health, University of Sydney; McGill University","keywords":"Epigenetics; Epigenome; CRISPR; Genome editing; DNA methylation; Computational biology; Biology; DNA; Genetics; Bioinformatics; Gene; Gene expression","score_opus":0.026558951062383093,"score_gpt":0.3539314303216908,"score_spread":0.3273724792593077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366829167","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018654043,0.9773281,0.019113459,0.000020271355,0.0008578712,0.0005337299,0.0001722681,0.000042695345,0.0000661939],"genre_scores_gemma":[0.0069807055,0.9866291,0.0016169092,0.000030636806,0.0018255595,0.00007047182,0.002505736,0.00014455525,0.00019631958],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980628,0.000113681956,0.0007903524,0.000462869,0.00026613811,0.0003041808],"domain_scores_gemma":[0.99880975,0.000110298584,0.00045003134,0.0004329752,0.00010128536,0.00009565656],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005254768,0.00040777426,0.001027511,0.0002502557,0.00005536433,0.000016256114,0.00026792585,0.00034880062,0.000016508548],"category_scores_gemma":[0.00031485982,0.00035051766,0.00025778404,0.00054691004,0.00009839283,0.0000033965725,0.000081159465,0.00014794338,0.0000120260465],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037273177,0.00011561326,0.00005116804,0.05316696,0.0005072769,0.000016157055,0.00009450661,0.00005614385,0.32210883,0.0000019151212,0.01326354,0.6105806],"study_design_scores_gemma":[0.00053767674,0.00025510148,0.00006628476,0.010565463,0.0006101389,0.000023636147,0.0000818965,0.0005306098,0.037273273,0.0000047752605,0.9493885,0.00066265947],"about_ca_topic_score_codex":0.000047670685,"about_ca_topic_score_gemma":0.000004773174,"teacher_disagreement_score":0.9361249,"about_ca_system_score_codex":0.000031178,"about_ca_system_score_gemma":0.00011538572,"threshold_uncertainty_score":0.9998947},"labels":[],"label_agreement":null},{"id":"W4366998803","doi":"10.1038/s41551-023-01032-2","title":"Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes","year":2023,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; University of California, San Francisco; National Center for Advancing Translational Sciences; Fondation ARC pour la Recherche sur le Cancer; Canadian Institutes of Health Research; Innovative Genomics Institute; Simons Foundation; CIHR Skin Research Training Centre; Cancer Research Institute; Parker Institute for Cancer Immunotherapy; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; Government of Canada","keywords":"CRISPR; Ribonucleoprotein; Genome editing; Electroporation; Trans-activating crRNA; Biology; Genome engineering; Molecular biology; Gene delivery; Cas9; Homology directed repair; Transfection; Peptide; Guide RNA; Cell biology; Computational biology; Gene; RNA; Genetics; Biochemistry; DNA repair","score_opus":0.005084441370596367,"score_gpt":0.26871782657621873,"score_spread":0.26363338520562235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366998803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91238,0.01296032,0.0722586,0.00020661986,0.001360228,0.00046108346,0.00017544445,0.00011258658,0.00008512836],"genre_scores_gemma":[0.9979428,0.00010296153,0.0011161207,0.000034353645,0.00045698317,0.00002692328,0.000252593,0.000028883249,0.000038381855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990185,0.0000070036735,0.00028193268,0.00019607483,0.00024074625,0.00025576446],"domain_scores_gemma":[0.99938405,0.0001816397,0.00006228465,0.00021562634,0.0000880636,0.00006835895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030818005,0.00014038752,0.00019108196,0.000115329676,0.00004358233,0.0000052268842,0.00023065598,0.00028392806,0.00000449897],"category_scores_gemma":[0.00041095464,0.000109605986,0.00013287968,0.0002919003,0.0000738035,0.0000015641679,0.00011286798,0.00015468588,8.48969e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001501297,0.000023384737,0.000058259884,0.0002862491,0.00007998241,0.000001383534,0.000046200385,0.016471632,0.978931,0.000088579895,0.0029921331,0.0010061638],"study_design_scores_gemma":[0.00092306547,0.0001897806,0.005085849,0.00012664146,0.00005192313,0.000006234937,0.0001176291,0.055204142,0.9003864,0.0000040239956,0.037685487,0.00021883582],"about_ca_topic_score_codex":0.0000058222654,"about_ca_topic_score_gemma":7.645403e-7,"teacher_disagreement_score":0.08556281,"about_ca_system_score_codex":0.000017383973,"about_ca_system_score_gemma":0.000047471913,"threshold_uncertainty_score":0.44696024},"labels":[],"label_agreement":null},{"id":"W4367368423","doi":"10.1089/hum.2023.059","title":"Advances in CRISPR/Cas9 Genome Editing for the Treatment of Muscular Dystrophies","year":2023,"lang":"en","type":"review","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Cas9; Muscular dystrophy; Duchenne muscular dystrophy; Biology; Genetic enhancement; Computational biology; Genetics; Gene","score_opus":0.054704643033502386,"score_gpt":0.4087134899131489,"score_spread":0.3540088468796465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367368423","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009995553,0.9964551,0.0011845219,0.000005289478,0.00021080977,0.0010403722,0.00006659202,0.000013255094,0.000024518136],"genre_scores_gemma":[0.00030966767,0.9971949,0.00017351717,0.000005231941,0.0011425419,0.00061372423,0.0002996171,0.000084502986,0.00017628241],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99885803,0.00003996293,0.00041131803,0.0003420347,0.00008947446,0.00025917933],"domain_scores_gemma":[0.9992784,0.000045000183,0.0001555747,0.00045890844,0.00003373665,0.000028340366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014127768,0.00031929798,0.00066785485,0.00009754672,0.000081022205,0.000013742378,0.00025762737,0.00015688849,0.0000078189805],"category_scores_gemma":[0.000008082465,0.00021234881,0.00048521554,0.00011719372,0.00005255201,0.0000016222242,0.000025788553,0.00005511656,0.0000021689843],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018819963,0.00009696283,0.0000027219653,0.0023395966,0.0004183334,0.000005529568,0.00018917218,0.0006739481,0.008753553,0.00002534549,0.00004706685,0.98742896],"study_design_scores_gemma":[0.00044548133,0.0006303159,0.000012071753,0.00028340626,0.00010459123,0.0000054419024,0.00004631937,0.00000548481,0.002975799,0.00002658184,0.9952575,0.00020702384],"about_ca_topic_score_codex":0.000010663579,"about_ca_topic_score_gemma":0.00004377189,"teacher_disagreement_score":0.9952104,"about_ca_system_score_codex":0.000027066919,"about_ca_system_score_gemma":0.000038332797,"threshold_uncertainty_score":0.8659333},"labels":[],"label_agreement":null},{"id":"W4367626055","doi":"10.29173/eureka28787","title":"Featured Research Images","year":2023,"lang":"en","type":"article","venue":"Eureka","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Stars; Degranulation; Art; Art history; Engineering; Biology; Computer science; Computer vision","score_opus":0.03081933972759238,"score_gpt":0.4147068257025321,"score_spread":0.3838874859749397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367626055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96291304,0.0035273002,0.0017182314,0.0015215622,0.00057033,0.00022808286,0.000022281265,0.00014262216,0.029356569],"genre_scores_gemma":[0.97685343,0.00023793931,0.0002639976,0.000044455774,0.0003735023,0.000013012651,0.000059956437,0.000018132705,0.022135591],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994055,0.00002672836,0.000052501644,0.0001719676,0.000116100564,0.00022718836],"domain_scores_gemma":[0.9996754,0.000010141212,0.000005305573,0.00021922159,0.00004435567,0.000045588582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026023778,0.00005477843,0.00004310741,0.00005480294,0.000056288765,0.000016824906,0.00011447792,0.000060143106,0.000031518022],"category_scores_gemma":[0.00009797877,0.00005250015,0.00003225733,0.00021207005,0.000027973485,6.199749e-7,0.00009686006,0.00009227652,0.00031374214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000061126843,0.0000046478476,0.00027582905,0.0000070660935,0.000007730193,0.0000067641745,0.000027443333,0.000134742,0.7317528,0.000023846625,0.26609224,0.0016607502],"study_design_scores_gemma":[0.00013442281,0.00005973836,0.013090964,0.0000045052216,0.0000017369482,0.000004995634,0.000062193365,0.000044829252,0.56039757,0.00005780177,0.42605776,0.00008346827],"about_ca_topic_score_codex":0.0000033344224,"about_ca_topic_score_gemma":0.0000040566015,"teacher_disagreement_score":0.17135526,"about_ca_system_score_codex":0.000002937662,"about_ca_system_score_gemma":0.000015320911,"threshold_uncertainty_score":0.40326253},"labels":[],"label_agreement":null},{"id":"W4372204664","doi":"10.3791/65131-v","title":"JoVE Video Dataset","year":2023,"lang":"pt","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé","keywords":"Biology; Electroporation; Oviduct; Somatic cell; Cell biology; Genome editing; Germline; CRISPR; Computational biology; Cancer research; Genetics; Gene","score_opus":0.013158282106104332,"score_gpt":0.33046469911921283,"score_spread":0.3173064170131085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4372204664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71647775,0.026199564,0.14098433,0.0124123925,0.012992902,0.002676483,0.030693622,0.0009849853,0.056577973],"genre_scores_gemma":[0.94746315,0.0016898698,0.0002456871,0.0006651113,0.0006847688,0.000017214616,0.013452942,0.000059405585,0.03572187],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988323,0.000020929692,0.00020003926,0.0004185073,0.00012432289,0.0004039159],"domain_scores_gemma":[0.999193,0.000013508816,0.000026548687,0.000602628,0.00002687596,0.00013743133],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016509075,0.0001969182,0.00013905906,0.00006411414,0.000060724517,0.000039156686,0.00023163523,0.00018596518,0.00035529578],"category_scores_gemma":[0.000061162886,0.00019953863,0.000083648396,0.00022651468,0.00003321782,0.0000018162498,0.0003112983,0.00009275582,0.0013715494],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015426913,0.000021566268,0.00027046417,0.000053421347,0.000080283695,0.000017913868,0.000040928804,0.0008419489,0.1964776,0.00004975932,0.7989576,0.0031731087],"study_design_scores_gemma":[0.00038197634,0.00013903668,0.0014593411,0.000013552254,0.00003214128,0.00001274447,0.00021700781,0.0022595439,0.17755234,0.0000141787095,0.8175891,0.0003290107],"about_ca_topic_score_codex":0.000024022298,"about_ca_topic_score_gemma":0.00004779978,"teacher_disagreement_score":0.23098537,"about_ca_system_score_codex":0.000006916527,"about_ca_system_score_gemma":0.00004257159,"threshold_uncertainty_score":0.999406},"labels":[],"label_agreement":null},{"id":"W4372347697","doi":"10.3791/65131","title":"Somatic Genome-Engineered Mouse Models Using &lt;em&gt;In Vivo&lt;/em&gt; Microinjection and Electroporation","year":2023,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé","keywords":"Biology; Electroporation; Somatic cell; Cell biology; Oviduct; Germline; Genome editing; Cancer research; Molecular biology; Genetics; CRISPR; Gene","score_opus":0.01837721938461534,"score_gpt":0.3617383950829139,"score_spread":0.34336117569829855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4372347697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9450866,0.0024184072,0.052162897,0.0000097024,0.00013642349,0.00014616735,0.00000426303,0.000013970639,0.000021546557],"genre_scores_gemma":[0.99545324,0.0007170176,0.003406713,0.000022053073,0.00017073852,0.0000063012253,0.000023709283,0.00004008055,0.00016016193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988028,0.000053316915,0.00047292592,0.00019109547,0.00021650488,0.00026337444],"domain_scores_gemma":[0.99949366,0.0000072662424,0.00017575681,0.00014211204,0.000086026754,0.00009519703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028547423,0.00018095228,0.0002497396,0.0002636496,0.000055932098,0.000054186916,0.00009960596,0.00012115189,0.0000119718725],"category_scores_gemma":[0.00003197942,0.00018391106,0.000089012414,0.0002073786,0.000014087759,0.00002367672,0.00004964699,0.000091829424,0.0000014950616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009831437,0.000059457903,0.000033927703,0.000026646929,0.00006812851,0.000009274365,0.0006152582,0.021043701,0.9777824,0.000009837544,0.00015190423,0.000101150334],"study_design_scores_gemma":[0.0014796898,0.000278091,0.00015299351,0.00003125586,0.000024036468,0.00008195143,0.00037762997,0.046529014,0.95043933,0.000057143603,0.00035731855,0.00019155815],"about_ca_topic_score_codex":0.00000423943,"about_ca_topic_score_gemma":0.0000062117474,"teacher_disagreement_score":0.050366603,"about_ca_system_score_codex":0.00006554073,"about_ca_system_score_gemma":0.000049421356,"threshold_uncertainty_score":0.7499675},"labels":[],"label_agreement":null},{"id":"W4375930638","doi":"10.17504/protocols.io.36wgqj48yvk5/v1","title":"CRISPR/Cas9 generation of knock-out iPSCs v1","year":2022,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stemcell Technologies","funders":"","keywords":"CRISPR; Induced pluripotent stem cell; Gene knockin; Cas9; Genome editing; Lipofectamine; Transfection; Biology; Subgenomic mRNA; Gene knockout; Computational biology; Recombinant DNA; Genetics; Gene; Molecular biology; Cell biology; Embryonic stem cell; Vector (molecular biology)","score_opus":0.02690513982887454,"score_gpt":0.33536157330894967,"score_spread":0.3084564334800751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4375930638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73005223,0.006555769,0.24118285,0.00023023793,0.0029123842,0.0006267567,0.00019209656,0.000054643624,0.018193042],"genre_scores_gemma":[0.9872706,0.00069109234,0.0046354025,0.00010827313,0.00067397894,0.000069256545,0.0010991963,0.000042535805,0.00540968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988933,0.00003698355,0.00029534232,0.00043474574,0.0001673511,0.00017227032],"domain_scores_gemma":[0.9991463,0.000004927746,0.00009552146,0.0006271336,0.000071831964,0.00005428185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014181777,0.00020994125,0.00021144131,0.00005901653,0.00004209508,0.000017127053,0.0002628358,0.00024768827,0.00047505563],"category_scores_gemma":[0.000036538306,0.0002229946,0.00017308898,0.000035774658,0.000024058027,7.1047e-7,0.0008369227,0.00021734486,0.0000051037523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016429396,0.00005647381,0.00042696611,0.00013910214,0.00012106343,0.0000023929117,0.00009704843,0.035370447,0.9423953,0.000120007826,0.01904201,0.0022127475],"study_design_scores_gemma":[0.00022093301,0.00014082933,0.00035110355,0.000010931178,0.000048981852,0.0000050887265,0.00010056837,0.0024657259,0.9215189,0.00005265872,0.074728,0.00035626223],"about_ca_topic_score_codex":0.000053164524,"about_ca_topic_score_gemma":0.00006821466,"teacher_disagreement_score":0.25721836,"about_ca_system_score_codex":0.000017271917,"about_ca_system_score_gemma":0.000098575816,"threshold_uncertainty_score":0.90934557},"labels":[],"label_agreement":null},{"id":"W4375955770","doi":"10.1093/bioinformatics/btad309","title":"Genome mining for anti-CRISPR operons using machine learning","year":2023,"lang":"en","type":"article","venue":"Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; University of Nebraska-Lincoln; University of Toronto; U.S. Department of Agriculture","keywords":"CRISPR; Genome; Operon; Computational biology; Context (archaeology); Computer science; Python (programming language); Gene; Biology; Genetics; Programming language","score_opus":0.02191280019472707,"score_gpt":0.3098302355894656,"score_spread":0.2879174353947385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4375955770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83434296,0.00036650393,0.16437337,0.0000341462,0.00020805164,0.00022990389,0.000048379014,0.000075139724,0.00032154637],"genre_scores_gemma":[0.937066,0.00027427007,0.06079191,0.00008545339,0.00027007237,0.000019190755,0.000674068,0.00005092976,0.00076808815],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99925435,0.000007116564,0.00023574762,0.000117601856,0.00008260038,0.00030260795],"domain_scores_gemma":[0.9996468,0.00001427646,0.00005432447,0.00017824897,0.00004100834,0.000065342676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018842173,0.00013120272,0.00012487364,0.000079985824,0.00014093137,0.000035468704,0.00012861118,0.00008916124,0.0000061325404],"category_scores_gemma":[0.00009421749,0.00013115158,0.00007872621,0.00013920355,0.00002105867,0.000005500395,0.00011359036,0.00005644648,0.000018177709],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001921406,0.000016586268,0.0030420022,0.00027081175,0.00009497427,0.0000021112883,0.0008583393,0.109733425,0.88214535,0.000024809826,0.0006440766,0.0031482782],"study_design_scores_gemma":[0.00073839293,0.00021002303,0.0018898643,0.000027392374,0.000040907522,0.00002708554,0.000996263,0.784853,0.09368828,0.000005868796,0.11709722,0.0004257335],"about_ca_topic_score_codex":0.000004365931,"about_ca_topic_score_gemma":0.000003915827,"teacher_disagreement_score":0.7884571,"about_ca_system_score_codex":0.000009587713,"about_ca_system_score_gemma":0.000032358697,"threshold_uncertainty_score":0.5348206},"labels":[],"label_agreement":null},{"id":"W4376133442","doi":"10.1093/nar/gkad375","title":"OnTarget: <i>in silico</i> design of MiniPromoters for targeted delivery of expression","year":2023,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Weston Brain Institute; Genome Canada","keywords":"Biology; Enhancer; Computational biology; Promoter; In silico; Chromatin; Bioinformatics; Gene; Gene expression; Genetics","score_opus":0.04367789731131333,"score_gpt":0.36558737145634657,"score_spread":0.32190947414503324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376133442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99258274,0.00040443,0.006375201,0.000039025403,0.00004839013,0.0004048326,0.000024995265,0.000008495191,0.00011187454],"genre_scores_gemma":[0.99487144,0.00021179856,0.0044731596,0.0000062652866,0.00004167989,0.000048287246,0.000050023988,0.000023818217,0.00027354364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989333,0.000076192606,0.00021394032,0.00023229772,0.00022541608,0.0003188445],"domain_scores_gemma":[0.99943143,0.00007914359,0.000027810433,0.00026769284,0.00014269105,0.000051259703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007903092,0.00008123292,0.00014319997,0.00018214346,0.00003051819,0.000004359861,0.00022270388,0.00012278066,0.000015342006],"category_scores_gemma":[0.0001709689,0.00007957412,0.00006330208,0.0002999125,0.00007823218,0.000002631202,0.00012983856,0.00008861389,0.0000038620556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020911612,0.00004148051,0.00096579286,0.000096085845,0.000012044521,0.0000016026335,0.00016759575,0.0021720245,0.9906208,0.000004276281,0.0039953836,0.0017138276],"study_design_scores_gemma":[0.0005408212,0.00044721464,0.002711436,0.000042284584,0.0000022042216,6.0375436e-7,0.00023257078,0.0024525619,0.9913752,0.000046475245,0.0020719045,0.00007671745],"about_ca_topic_score_codex":0.000031929394,"about_ca_topic_score_gemma":0.000008192115,"teacher_disagreement_score":0.0022886682,"about_ca_system_score_codex":0.000011850411,"about_ca_system_score_gemma":0.0000693802,"threshold_uncertainty_score":0.32449386},"labels":[],"label_agreement":null},{"id":"W4376141117","doi":"10.1101/2023.05.10.540216","title":"<i>De novo</i> synthesis of a conjugative system from human gut metagenomic data for targeted delivery of Cas9 antimicrobials","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Metagenomics; Computational biology; Contig; CRISPR; Biology; Plasmid; Cas9; Genetics; Genome; Gene","score_opus":0.023727518718506726,"score_gpt":0.26968513260712884,"score_spread":0.2459576138886221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376141117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96333206,0.0018409132,0.015062134,0.00001549706,0.00045414935,0.00076502573,0.018453903,0.00007419176,0.0000021296223],"genre_scores_gemma":[0.9861524,0.00024193044,0.012960375,0.000017682032,0.00030501446,0.00012860933,0.000042382646,0.00014765051,0.0000039475394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976536,0.00010594732,0.0007561008,0.00096217816,0.00014994992,0.00037222327],"domain_scores_gemma":[0.99676275,0.000112390226,0.00057380553,0.0020454,0.0003932795,0.0001123788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006831188,0.00041894286,0.0008199338,0.00014259752,0.00006608363,0.00003889746,0.0010196628,0.00049270195,0.0000059543627],"category_scores_gemma":[0.00032322065,0.00048400502,0.00021842051,0.00013921259,0.000110927154,0.0000062007325,0.0009902433,0.00017441477,0.0000033406297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055089666,0.00005060971,0.00040832194,0.0012070321,0.0008714139,0.00000734157,0.000007903262,0.00075019436,0.9961322,0.000028018221,0.00048070087,0.0000011635389],"study_design_scores_gemma":[0.00039207665,0.000050674502,0.0041409545,0.0005133763,0.0004833309,2.3020446e-8,0.0000146889415,0.0004885044,0.9926568,4.804864e-7,0.00081885065,0.00044021217],"about_ca_topic_score_codex":0.00030018153,"about_ca_topic_score_gemma":0.000013318061,"teacher_disagreement_score":0.022820352,"about_ca_system_score_codex":0.00006604961,"about_ca_system_score_gemma":0.000396684,"threshold_uncertainty_score":0.99976116},"labels":[],"label_agreement":null},{"id":"W4377019631","doi":"10.1101/2023.05.16.541004","title":"CRISPR-based diagnostics detects invasive insect pests","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Agriculture and Agri-Food Canada; Animal and Plant Health Inspection Service; Indian Agricultural Research Institute; National Institutes of Health; U.S. Department of Agriculture; Indian Council of Agricultural Research; University of Florida","keywords":"CRISPR; Insect; Biology; Biotechnology; Ecology; Genetics; Gene","score_opus":0.016882554982487207,"score_gpt":0.25539964650366315,"score_spread":0.23851709152117595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377019631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9701599,0.0029842025,0.02307366,0.00015545261,0.0021452457,0.00075764774,0.0003428485,0.00037449485,0.000006557395],"genre_scores_gemma":[0.9931803,0.0014976469,0.0034407205,0.00028506992,0.0009923348,0.00030677818,0.000005481589,0.00028016392,0.000011516064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99716014,0.000097470016,0.0004801505,0.0012168917,0.00034235508,0.0007029775],"domain_scores_gemma":[0.99732566,0.00011632049,0.0002301793,0.001605363,0.00038974587,0.00033274668],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003530694,0.00068700605,0.0004806784,0.00024729257,0.0001302554,0.000146055,0.00067267707,0.0008671916,0.0000141980145],"category_scores_gemma":[0.0014184279,0.0008051987,0.000260609,0.00032665342,0.00010302913,0.000004652993,0.0007195418,0.00061215786,0.000098722034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029064115,0.00007801073,0.006767247,0.0005163583,0.00016375273,0.000105635634,0.000004345847,0.004671624,0.9850751,0.000015253674,0.0025712335,0.0000023480882],"study_design_scores_gemma":[0.0005096646,0.00015196759,0.058634013,0.00030450686,0.00010988922,2.5071843e-8,0.000001978172,0.00038466827,0.93426025,0.0000015533944,0.0047169835,0.00092450605],"about_ca_topic_score_codex":0.000044967306,"about_ca_topic_score_gemma":0.000041377698,"teacher_disagreement_score":0.051866766,"about_ca_system_score_codex":0.00009123785,"about_ca_system_score_gemma":0.0008432648,"threshold_uncertainty_score":0.9994399},"labels":[],"label_agreement":null},{"id":"W4377086571","doi":"10.1016/j.cels.2023.04.003","title":"Reproducibility metrics for context-specific CRISPR screens","year":2023,"lang":"en","type":"article","venue":"Cell Systems","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Ontario Research Foundation; Canada Research Chairs; National Human Genome Research Institute; GlaxoSmithKline; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Reproducibility; Context (archaeology); Computational biology; Computer science; Biology; Genetics; Mathematics; Statistics; Gene","score_opus":0.030978199663751753,"score_gpt":0.3099705553019095,"score_spread":0.2789923556381577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377086571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76990527,0.028565599,0.19149652,0.00017135839,0.0036004002,0.00190393,0.00017346234,0.00022825247,0.003955185],"genre_scores_gemma":[0.9927936,0.00026177944,0.00017335138,0.000024268944,0.0006196436,0.00008786749,0.00015166808,0.000031777843,0.0058560027],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861866,0.000028440161,0.0002382622,0.00074426056,0.00010289435,0.0002675066],"domain_scores_gemma":[0.9986488,0.000033694498,0.000045167842,0.0010747636,0.00012126141,0.000076307915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008672239,0.00012479331,0.00016143921,0.000067029236,0.000072029834,0.00003037287,0.00015791727,0.00011332607,0.000003037256],"category_scores_gemma":[0.00022040086,0.00012336107,0.00010745691,0.00024120221,0.000023516344,0.0000014011608,0.00006519085,0.000046857724,0.00003601259],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004781668,0.000046510893,0.0018145251,0.0003451315,0.00004439757,0.0000035151047,0.000095081006,0.00280881,0.8191437,0.00023603413,0.17084941,0.0045650285],"study_design_scores_gemma":[0.00038984188,0.0001158821,0.00083325786,0.000009575082,0.000010286014,0.000003757862,0.00039186247,0.0013262845,0.31956804,0.000012301636,0.67715245,0.00018646542],"about_ca_topic_score_codex":0.00003640808,"about_ca_topic_score_gemma":0.000007690005,"teacher_disagreement_score":0.506303,"about_ca_system_score_codex":0.000011866189,"about_ca_system_score_gemma":0.000024416802,"threshold_uncertainty_score":0.5030518},"labels":[],"label_agreement":null},{"id":"W4377094532","doi":"10.1002/advs.202300656","title":"Repurposing CRISPR/Cas to Discover SARS‐CoV‐2 Detecting and Neutralizing Aptamers","year":2023,"lang":"en","type":"article","venue":"Advanced Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Beijing Municipal Natural Science Foundation; Shenzhen Municipal Science and Technology Innovation Council; Guangdong Science and Technology Department; University of Toronto; Shenzhen University; National Natural Science Foundation of China","keywords":"Aptamer; CRISPR; Systematic evolution of ligands by exponential enrichment; Computational biology; RNA; Biology; Repurposing; Context (archaeology); Virology; Chemistry; Molecular biology; Gene; Genetics","score_opus":0.013788757314998644,"score_gpt":0.3595580548453265,"score_spread":0.34576929753032787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377094532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97574556,0.00022779449,0.02325448,0.000108863285,0.0002280915,0.00011524617,0.0000019043246,0.000040577685,0.00027749094],"genre_scores_gemma":[0.99395293,0.0001084806,0.0055534737,0.00020890108,0.000051284376,0.000010530242,0.0000018920467,0.000014168685,0.00009831087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892646,0.00000736495,0.0001122838,0.00044631705,0.00013665474,0.0003709031],"domain_scores_gemma":[0.9995911,0.0000127002695,0.00002419221,0.00024496487,0.000035012057,0.000092003545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466616,0.00010426619,0.00007889503,0.00009639759,0.00021607635,0.000060634644,0.00017108017,0.000029035335,5.343024e-7],"category_scores_gemma":[0.00021679871,0.00010570664,0.000025215588,0.0005699624,0.00011160829,0.000016622052,0.00021210974,0.000056319677,0.000006758734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006170926,0.0000017885227,0.00037832384,0.0000064443725,0.0000019235033,0.0000026462258,0.0001647983,0.004441944,0.9737628,0.000022277829,0.000032546795,0.021178331],"study_design_scores_gemma":[0.00010865883,0.00007438914,0.0038469688,0.00002052565,0.0000031605848,0.00001338593,0.0002947259,0.0010233511,0.98870164,0.00004042775,0.0057116686,0.0001611053],"about_ca_topic_score_codex":0.000012986171,"about_ca_topic_score_gemma":0.000028289713,"teacher_disagreement_score":0.021017225,"about_ca_system_score_codex":0.000014536749,"about_ca_system_score_gemma":0.000031819614,"threshold_uncertainty_score":0.43105915},"labels":[],"label_agreement":null},{"id":"W4377142511","doi":"10.1101/2023.05.19.541456","title":"Cancer cells co-evolve with retrotransposons to mitigate viral mimicry","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Biology; Retrotransposon; Innate immune system; APOBEC; Genome; Pancreatic cancer; Tumor microenvironment; Transcriptome; Alu element; Immune system; Genetics; Cancer; Gene; Cancer research; Human genome; Transposable element; Gene expression","score_opus":0.01014149067673008,"score_gpt":0.25814726764890666,"score_spread":0.24800577697217657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377142511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98403555,0.0010942557,0.011310522,0.00030620146,0.0010535682,0.00081764715,0.0011436968,0.00022973641,0.0000087984145],"genre_scores_gemma":[0.99261206,0.00047528578,0.0050422587,0.00028575354,0.0008079113,0.00044469655,0.0000040149353,0.00026384016,0.00006418765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974562,0.000046197012,0.00034714732,0.0011778644,0.0002856745,0.0006868984],"domain_scores_gemma":[0.998037,0.000011648466,0.00012821882,0.0011934995,0.00024439118,0.00038525704],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020559168,0.0006010408,0.00043885867,0.00016898592,0.00009054774,0.00010280718,0.0005422761,0.0005424172,0.00002275859],"category_scores_gemma":[0.000028103452,0.0006304331,0.00016996027,0.00025977948,0.000085910484,0.000004685617,0.00027509712,0.00048004097,0.0000734042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006926754,0.000034329056,0.002154137,0.00024098913,0.00024392341,0.000038026683,0.00000925604,0.0074370853,0.98683846,0.0000069612092,0.002926056,0.0000014890581],"study_design_scores_gemma":[0.0003843867,0.00014851184,0.016986113,0.00032115224,0.000111395944,1.8513422e-8,0.000002619021,0.000118717566,0.9682853,2.49945e-7,0.012793169,0.00084834883],"about_ca_topic_score_codex":0.00010180479,"about_ca_topic_score_gemma":0.00003770207,"teacher_disagreement_score":0.018553162,"about_ca_system_score_codex":0.00009038459,"about_ca_system_score_gemma":0.00042235517,"threshold_uncertainty_score":0.9996147},"labels":[],"label_agreement":null},{"id":"W4378231868","doi":"10.3389/fmed.2023.1128557","title":"Prime editing strategies to mediate exon skipping in DMD gene","year":2023,"lang":"en","type":"article","venue":"Frontiers in Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Exon; Tandem exon duplication; Frameshift mutation; Exon shuffling; Exon trapping; Exon skipping; Duchenne muscular dystrophy; Splice site mutation; Molecular biology; Genetics; Biology; splice; Gene; Mutation; RNA splicing; Alternative splicing; RNA","score_opus":0.008745567549923535,"score_gpt":0.3030129209092061,"score_spread":0.29426735335928256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378231868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91377187,0.0023690998,0.07935565,0.0010727367,0.0021183547,0.00024762677,0.000003819186,0.000042163683,0.0010186633],"genre_scores_gemma":[0.9922811,0.0005929483,0.0053701634,0.0002084948,0.0011048905,0.000036120215,0.00009784997,0.000026773214,0.00028167697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894136,0.00002569528,0.0002539041,0.00028680012,0.00014802802,0.0003442066],"domain_scores_gemma":[0.99965644,0.000009690387,0.00002830205,0.00020107084,0.00002033412,0.0000841362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044517743,0.00013280894,0.00022492385,0.00028073599,0.00002162919,0.000007822512,0.00015566048,0.00009602655,0.000008059999],"category_scores_gemma":[0.00020518896,0.00012914279,0.000023006456,0.0004335881,0.000039641673,0.000003774677,0.000077200886,0.00011748329,0.0000062610184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005477917,0.000020964373,0.028228253,0.00008099413,0.00003849683,0.00009354557,0.0021034402,0.015227079,0.8914358,0.000018636878,0.04271554,0.01998245],"study_design_scores_gemma":[0.006486026,0.0012999075,0.24865608,0.0010963543,0.00005958286,0.00003439355,0.0332682,0.013658078,0.59253836,0.0011843545,0.10019707,0.0015215875],"about_ca_topic_score_codex":0.0000424758,"about_ca_topic_score_gemma":0.000081578226,"teacher_disagreement_score":0.29889745,"about_ca_system_score_codex":0.000025603122,"about_ca_system_score_gemma":0.00003382193,"threshold_uncertainty_score":0.52662903},"labels":[],"label_agreement":null},{"id":"W4378389766","doi":"10.30683/1929-2279.2023.12.5","title":"Targeting Snail1 by CRISPR/Cas9 System Inhibits the Proliferation and Migration of Human Gastric Cancer Cells","year":2023,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health","keywords":"CRISPR; Cas9; Nuclease; Biology; Cancer; Cell growth; Cell; HEK 293 cells; Cancer cell; Repressor; Cancer research; Cell biology; Cell culture; Gene; Genetics; Gene expression","score_opus":0.020193709430923343,"score_gpt":0.3894650224623964,"score_spread":0.36927131303147304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378389766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887758,0.00988087,0.000396515,0.00065712765,0.00009713045,0.00014961929,0.000023443223,0.0000037942393,0.000015680838],"genre_scores_gemma":[0.9940334,0.0053655636,0.000042010695,0.000014025561,0.0003763043,0.000022991231,0.000016242639,0.000012820276,0.00011663585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989939,0.00009491298,0.0002795407,0.00011218038,0.0003223054,0.00019719817],"domain_scores_gemma":[0.9993158,0.000025273504,0.00012861368,0.00009128433,0.00038156516,0.000057494653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009274329,0.0000735898,0.00011676502,0.000107861335,0.00012320481,0.00004305445,0.00012643021,0.000053094744,0.000007720678],"category_scores_gemma":[0.00004878806,0.000051404233,0.00003573655,0.00023622747,0.00005539705,0.00000916243,0.000060503946,0.00016755852,6.59784e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003286287,0.00000772617,0.00273724,0.000104942104,0.000039147657,0.0000011761941,0.00012967052,0.001979593,0.9623355,0.00000810429,0.031867538,0.0007564823],"study_design_scores_gemma":[0.00024238178,0.00019674216,0.001011097,0.00009776482,0.000013804521,0.000005513374,0.0005385512,0.0009320289,0.9910717,0.000008096508,0.0058276094,0.000054692093],"about_ca_topic_score_codex":0.00015707884,"about_ca_topic_score_gemma":0.00011934751,"teacher_disagreement_score":0.028736202,"about_ca_system_score_codex":0.000031152373,"about_ca_system_score_gemma":0.00009382767,"threshold_uncertainty_score":0.20962037},"labels":[],"label_agreement":null},{"id":"W4378533274","doi":"10.1101/2023.05.26.542436","title":"Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Université de Montréal; Terry Fox Research Institute; Fonds de Recherche du Québec - Santé; Sleep Research Society Foundation; Cancer Research Society","keywords":"Haematopoiesis; Stem cell; Progenitor cell; Progenitor; Cell biology; Computer science; Biology","score_opus":0.01218149134845026,"score_gpt":0.2525201686064856,"score_spread":0.24033867725803532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378533274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957905,0.0012950483,0.000978662,0.000029986462,0.0009598142,0.0006294405,0.0001881798,0.00012262855,0.000005777793],"genre_scores_gemma":[0.9967176,0.00013877261,0.001956313,0.000020778441,0.0008322738,0.0001400675,0.0000013265835,0.00017088551,0.000021985146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779046,0.0000714118,0.0004970013,0.000921761,0.00027172337,0.0004476517],"domain_scores_gemma":[0.9983008,0.000029191542,0.00026168872,0.0010045944,0.00019901498,0.00020472796],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004130107,0.0004870531,0.0004971836,0.000118285105,0.00013045246,0.0001007812,0.00036067268,0.00050677336,0.000007097696],"category_scores_gemma":[0.000067338864,0.00053674926,0.000163823,0.0001612906,0.00012664925,0.0000042632623,0.0005579364,0.00038384335,0.000014032764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016674463,0.00006222788,0.0030142013,0.00082568,0.00013786534,0.000013381583,0.000016550966,0.0008104102,0.9946699,0.00002248666,0.00040852613,0.000002063518],"study_design_scores_gemma":[0.00032791018,0.00020349256,0.004284158,0.00037463714,0.00006719637,3.4984865e-8,0.0000078409175,0.00027707304,0.9930619,0.0000011688684,0.000901097,0.0004935199],"about_ca_topic_score_codex":0.00001213006,"about_ca_topic_score_gemma":0.0000012891768,"teacher_disagreement_score":0.0016080609,"about_ca_system_score_codex":0.000033556476,"about_ca_system_score_gemma":0.00016699034,"threshold_uncertainty_score":0.9997084},"labels":[],"label_agreement":null},{"id":"W4378715049","doi":"10.1186/s12864-023-09377-3","title":"ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid RPE1 and HCT116 cells","year":2023,"lang":"en","type":"article","venue":"BMC Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; University of Tokyo; Institute of Genetics; Japan Science and Technology Agency; Kato Memorial Bioscience Foundation; Uehara Memorial Foundation; Naito Foundation; Kanae Foundation for the Promotion of Medical Science; Sumitomo Foundation; Takeda Science Foundation","keywords":"CRISPR; Biology; Endogeny; Ploidy; Gene; DNA microarray; Genome editing; Genetics; Cell biology; DNA; Computational biology; Gene expression; Biochemistry","score_opus":0.021337222791589797,"score_gpt":0.2895664282340374,"score_spread":0.2682292054424476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378715049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935266,0.0004136797,0.00494229,0.00008755338,0.00019430614,0.00060092146,0.0001321672,0.00004013422,0.00006236539],"genre_scores_gemma":[0.9951153,0.00043580815,0.0028845435,0.00046542773,0.00026187423,0.00010221863,0.00021992215,0.000081814236,0.00043311942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985355,0.000018925626,0.00030833247,0.00052994856,0.000089290064,0.0005179961],"domain_scores_gemma":[0.9993639,0.000034420413,0.000040460076,0.00034714854,0.0000388221,0.00017525947],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020801582,0.00024338171,0.00023699341,0.00015417684,0.0001144708,0.00005146434,0.00020147278,0.00016589928,0.0000103829],"category_scores_gemma":[0.0000564113,0.00027962512,0.000093950366,0.00015763445,0.00003130943,0.0000036612385,0.00020978633,0.00008290515,0.000032928343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005579456,0.000019047136,0.0017652797,0.0000662981,0.000024944033,0.000009284647,0.00071665144,0.0027110612,0.99382544,0.0000057450998,0.00026194146,0.00053851627],"study_design_scores_gemma":[0.0008363315,0.00019148561,0.003755685,0.000011409291,0.000020961104,0.000015506697,0.00034141514,0.00048454126,0.9835454,0.000018022614,0.010414213,0.0003650181],"about_ca_topic_score_codex":0.000120498735,"about_ca_topic_score_gemma":0.00053548306,"teacher_disagreement_score":0.010280026,"about_ca_system_score_codex":0.000040416693,"about_ca_system_score_gemma":0.00007365527,"threshold_uncertainty_score":0.9999656},"labels":[],"label_agreement":null},{"id":"W4378746022","doi":"10.1007/978-1-0716-3159-1_16","title":"Eliciting Targeted Mutations in Medicago sativa Using CRISPR/Cas9-Mediated Genome Editing: A Potential Tool for the Improvement of Disease Resistance","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"","keywords":"CRISPR; Biology; Genome editing; Cas9; Genetics; Subgenomic mRNA; Medicago sativa; Computational biology; Plant disease resistance; Indel; Gene; Genotype; Botany","score_opus":0.015794756109579304,"score_gpt":0.4033028032016977,"score_spread":0.3875080470921184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378746022","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30823687,0.0010704058,0.6897863,0.00023833591,0.00017912521,0.00040568135,0.0000651003,0.000010764477,0.0000074200393],"genre_scores_gemma":[0.7652022,0.00011995172,0.23371075,0.00015888327,0.00016079623,0.0002184055,0.00036948067,0.000037320777,0.00002220106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984553,0.0002445794,0.0004637528,0.00037077945,0.000087668814,0.00037795666],"domain_scores_gemma":[0.99924755,0.00020096218,0.000120670855,0.00030401393,0.00007416612,0.000052622396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012087347,0.0001603603,0.00022084703,0.00016746185,0.000057915706,0.0000074297664,0.00021933773,0.00013926,0.0000059324275],"category_scores_gemma":[0.0018480833,0.00014258098,0.00011214001,0.00039799273,0.000115575,0.0000021197927,0.00013908865,0.00012010059,3.82994e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006526562,0.000020661748,0.00035988982,0.00005362042,0.000042383344,0.000007606862,0.000077919285,0.0129819885,0.98368376,0.00006673839,0.00001424577,0.0026258917],"study_design_scores_gemma":[0.0015911177,0.00018474607,0.005172534,0.000056856214,0.00007473995,0.0000025031022,0.00051619904,0.036693107,0.95009667,0.002719993,0.0025211442,0.0003704026],"about_ca_topic_score_codex":0.000028755405,"about_ca_topic_score_gemma":0.000032340155,"teacher_disagreement_score":0.45696536,"about_ca_system_score_codex":0.000024528144,"about_ca_system_score_gemma":0.00008468437,"threshold_uncertainty_score":0.58142835},"labels":[],"label_agreement":null},{"id":"W4378781294","doi":"10.1111/febs.16876","title":"Efficient <scp>CRISPR</scp> /Cas9 mediated large insertions using long single‐stranded oligonucleotide donors in <i>C. elegans</i>","year":2023,"lang":"en","type":"article","venue":"FEBS Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Oligonucleotide; Cas9; Caenorhabditis elegans; Biology; Genetics; Computational biology; DNA; Gene","score_opus":0.013697700502800387,"score_gpt":0.28896629969185583,"score_spread":0.27526859918905544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378781294","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829226,0.00071937987,0.015319678,0.00007308136,0.0005019982,0.00012425438,0.000024082958,0.000039653645,0.00027525992],"genre_scores_gemma":[0.9984458,0.00030658336,0.000441839,0.000119775534,0.00040733063,0.0000047974704,0.0000585889,0.000045922978,0.00016933325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839395,0.000067157394,0.00040488853,0.00027152413,0.0002213756,0.0006411262],"domain_scores_gemma":[0.9993722,0.000039650906,0.00009108558,0.00021139407,0.000081009464,0.00020469654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046657032,0.0002063833,0.00019573918,0.00024919296,0.00017725652,0.0000805876,0.00020113622,0.00016140453,0.00001458667],"category_scores_gemma":[0.00027178545,0.00020851215,0.00013791968,0.00051517185,0.000034033194,0.0000055775236,0.000089667206,0.00031900435,0.000027353419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016137285,0.00013231878,0.012081108,0.000020621801,0.00006217258,0.00015090629,0.00030172037,0.08863743,0.89645916,0.0000044518774,0.0019156875,0.00021826755],"study_design_scores_gemma":[0.0060632485,0.0005010324,0.13186973,0.0002879559,0.00014200759,0.001183358,0.001894193,0.06073473,0.762777,0.00007269653,0.033832237,0.00064184977],"about_ca_topic_score_codex":0.000017936833,"about_ca_topic_score_gemma":0.00017759204,"teacher_disagreement_score":0.13368222,"about_ca_system_score_codex":0.000049768907,"about_ca_system_score_gemma":0.00008930337,"threshold_uncertainty_score":0.8502879},"labels":[],"label_agreement":null},{"id":"W4379034368","doi":"10.2139/ssrn.4462091","title":"Costa Rican Consumer Perceptions of Gene-Editing","year":2023,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Puerto rican; Perception; Geography; Psychology; Sociology; Ethnology; Neuroscience","score_opus":0.009294909708405644,"score_gpt":0.30080264070579615,"score_spread":0.2915077309973905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379034368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8157596,0.007790622,0.17479537,0.00021701178,0.00085332064,0.00019555804,0.00010354543,0.000030800642,0.00025417842],"genre_scores_gemma":[0.9814867,0.0155560635,0.0009954687,0.000018689654,0.0009500223,0.000012876371,0.00020349954,0.00006293113,0.0007137755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979298,0.000041026902,0.0003663653,0.00030947666,0.00018399228,0.0011693538],"domain_scores_gemma":[0.99921685,0.000012206985,0.00020555635,0.00034442925,0.00013805044,0.000082929175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067584496,0.00021969377,0.00024452843,0.00011140779,0.00008640726,0.000025930065,0.0003408509,0.00025731148,0.000010402176],"category_scores_gemma":[0.000098355886,0.00022858592,0.0002515477,0.00007329381,0.00006304666,0.0000014877613,0.00023256382,0.0015846149,0.000007155567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074244395,0.00012304087,0.016073197,0.00017445501,0.0019128035,0.000010117678,0.0002813225,0.019900471,0.9359761,0.0016479255,0.0037221413,0.020104216],"study_design_scores_gemma":[0.009979955,0.0052624005,0.07128833,0.0016220799,0.0032095083,0.006430576,0.030874014,0.0056050615,0.665886,0.14542732,0.04596633,0.008448435],"about_ca_topic_score_codex":0.00005217439,"about_ca_topic_score_gemma":0.0004806959,"teacher_disagreement_score":0.27009007,"about_ca_system_score_codex":0.00013997682,"about_ca_system_score_gemma":0.0012751793,"threshold_uncertainty_score":0.9321463},"labels":[],"label_agreement":null},{"id":"W4379521490","doi":"10.21428/594757db.0ff990d1","title":"Navitas/Optimus: A Novel Computational Tool for enhanced CRISPR/Cas Genome Editing","year":2023,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"CRISPR; Genome editing; Computer science; Cas9; Subgenomic mRNA; Sequence (biology); Process (computing); Computational biology; Genome; Guide RNA; Artificial intelligence; Machine learning; Gene; Biology; Genetics; Programming language","score_opus":0.011766389510957568,"score_gpt":0.3190505601914406,"score_spread":0.3072841706804831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379521490","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23881163,0.00006456591,0.7600778,0.00013533692,0.00019545983,0.00018741297,0.00006049246,0.000053291915,0.00041401508],"genre_scores_gemma":[0.9650443,0.000013662322,0.03217246,0.0002012118,0.00063424686,0.00007725687,0.00069291936,0.000027709344,0.0011362145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992316,0.000003998176,0.00016140191,0.00026225002,0.00008969644,0.0002510876],"domain_scores_gemma":[0.9996811,0.000027809081,0.000026490708,0.00013670274,0.000082362625,0.00004552692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012435661,0.00011400434,0.00009386072,0.000041639556,0.0000715113,0.00002320509,0.00009882049,0.00007571777,0.000023638679],"category_scores_gemma":[0.00007432301,0.00011758438,0.000084368236,0.00010007862,0.000017077049,0.0000022205968,0.00006779883,0.000038389062,0.000025567055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012615591,0.000015994116,0.000026837679,0.00002752973,0.00003345046,5.381071e-7,0.00005460834,0.07810024,0.91861266,0.00014673971,0.0020574317,0.0009113524],"study_design_scores_gemma":[0.0016685379,0.00029159125,0.00531231,0.000016982418,0.000027689468,0.00001575159,0.00034029628,0.03328073,0.9195169,0.0003113969,0.038679495,0.0005383127],"about_ca_topic_score_codex":0.0000024060362,"about_ca_topic_score_gemma":0.000003602205,"teacher_disagreement_score":0.72790533,"about_ca_system_score_codex":0.000008365163,"about_ca_system_score_gemma":0.000026945912,"threshold_uncertainty_score":0.47949517},"labels":[],"label_agreement":null},{"id":"W4379742689","doi":"10.1089/ipm.10.03.04","title":"One and Done? How CRISPR Is Changing the Clinical Outlook for Multiple Diseases","year":2023,"lang":"en","type":"article","venue":"Inside Precision Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CARE Canada","funders":"","keywords":"CRISPR; Download; Medicine; Clinical microbiology; Family medicine; Internal medicine; Library science; Gerontology; Computer science; World Wide Web; Biology; Genetics","score_opus":0.05277204017940281,"score_gpt":0.39141394018710784,"score_spread":0.33864190000770505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379742689","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89565736,0.0063042436,0.074901305,0.02120653,0.0009395114,0.0007628833,0.000057531044,0.00007060806,0.00010002281],"genre_scores_gemma":[0.99383634,0.001821738,0.00067099964,0.0013455666,0.0011389651,0.00005541545,0.000073229894,0.00002456805,0.0010331607],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990726,0.000035675068,0.0001937142,0.0003124352,0.00015831718,0.00022722132],"domain_scores_gemma":[0.9990866,0.00035391486,0.00004552424,0.00033204426,0.0000706482,0.00011124464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054465217,0.00011745796,0.00018852265,0.00007175093,0.00010875387,0.000016114347,0.00013014807,0.00009022406,0.0000092654445],"category_scores_gemma":[0.0016431607,0.00008085491,0.00007197139,0.00012798177,0.00010193733,0.0000027522865,0.00016788008,0.000077367135,0.000004592722],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000491724,0.00009764546,0.024635937,0.0001933525,0.00027179185,0.000011305801,0.001530502,0.00023980503,0.29967517,0.000057166573,0.28840888,0.38438672],"study_design_scores_gemma":[0.0077517903,0.0018409365,0.13413753,0.0004472188,0.00035119135,0.000026055308,0.0027658376,0.015496978,0.119870834,0.0014028817,0.71516466,0.0007440699],"about_ca_topic_score_codex":0.0000040031027,"about_ca_topic_score_gemma":0.000012994244,"teacher_disagreement_score":0.4267558,"about_ca_system_score_codex":0.0000030330477,"about_ca_system_score_gemma":0.000015438178,"threshold_uncertainty_score":0.32971674},"labels":[],"label_agreement":null},{"id":"W4379769366","doi":"10.1186/s12864-023-09398-y","title":"Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons","year":2023,"lang":"en","type":"article","venue":"BMC Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Johns Hopkins University; Karolinska Institutet; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health","keywords":"Biology; Chromatin; Dopaminergic; Neuroscience; Midbrain; Cell culture; Computational biology; Cell biology; Genetics; Dopamine; Gene; Central nervous system","score_opus":0.040937490305234706,"score_gpt":0.35451992331687826,"score_spread":0.31358243301164357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379769366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936654,0.00047269408,0.004387439,0.00021386151,0.00028638286,0.00073889765,0.000050308354,0.000049888335,0.00013512828],"genre_scores_gemma":[0.97659177,0.000088211855,0.004825411,0.00026501543,0.00070680195,0.00035401195,0.00031954478,0.000089978384,0.016759275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989212,0.00004426505,0.00020553212,0.00033890884,0.000098538614,0.00039152152],"domain_scores_gemma":[0.99932945,0.00007584829,0.00005369052,0.00041584222,0.00005812071,0.00006704634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041046305,0.0001675876,0.000118432945,0.00003665559,0.00014066929,0.000050447386,0.00027314608,0.00009240936,0.0000051515567],"category_scores_gemma":[0.00039221797,0.00014034365,0.00012263481,0.00012417513,0.000032171953,0.0000025145355,0.00015652098,0.000086727756,0.000024167499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007769734,0.000018438726,0.00037109913,0.000052448762,0.000022686352,7.0839167e-7,0.00014102533,0.08674267,0.9088086,0.000050914085,0.0026834677,0.0010302509],"study_design_scores_gemma":[0.0011615817,0.0010655323,0.00084536045,0.000007049653,0.00006603177,0.000027563028,0.0003469991,0.32858717,0.62118864,0.00012134617,0.04614777,0.0004349791],"about_ca_topic_score_codex":0.0000117598465,"about_ca_topic_score_gemma":0.00006635022,"teacher_disagreement_score":0.28761998,"about_ca_system_score_codex":0.000012790586,"about_ca_system_score_gemma":0.00010664138,"threshold_uncertainty_score":0.5723048},"labels":[],"label_agreement":null},{"id":"W4379769519","doi":"10.3324/haematol.2023.283031","title":"Correcting the aberrant Fanconi anemia transcriptional program by gene therapy","year":2023,"lang":"en","type":"letter","venue":"Haematologica","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation","funders":"","keywords":"Fanconi anemia; Genetic enhancement; Anemia; Medicine; Gene; Genetics; Biology; Cancer research; Internal medicine; DNA repair","score_opus":0.02181332958894403,"score_gpt":0.30484142083161403,"score_spread":0.28302809124267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379769519","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3802561,0.060284935,0.012993542,0.5270475,0.008557882,0.0059361923,0.0008828187,0.0015322558,0.0025087344],"genre_scores_gemma":[0.2931894,0.008775587,0.004374108,0.6346682,0.01408909,0.003934563,0.01549747,0.00077385444,0.02469775],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99833333,0.00008167616,0.00029990936,0.00056042505,0.00022897817,0.00049567485],"domain_scores_gemma":[0.9992772,0.000049665392,0.000102864804,0.00047439194,0.000054506872,0.00004141955],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016103726,0.00036964368,0.00033106402,0.000033251345,0.00016894036,0.000061263665,0.00044800658,0.00081702386,0.000061188635],"category_scores_gemma":[0.00003811344,0.00024943048,0.00024557425,0.00011347438,0.000116565294,0.0000013155922,0.00006106853,0.00074690406,0.000043173597],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019180341,0.000026256397,0.000047916226,0.000055247467,0.000095167954,0.00009648558,0.000040934876,0.000037467053,0.044497576,0.000002562323,0.94589454,0.009186676],"study_design_scores_gemma":[0.000257048,0.00022538687,0.00012346977,0.00002265674,0.000024758272,0.0006718435,0.00002629431,0.000039976516,0.05316468,0.000027774866,0.94505525,0.00036084547],"about_ca_topic_score_codex":0.000016864908,"about_ca_topic_score_gemma":0.0000078629455,"teacher_disagreement_score":0.10762063,"about_ca_system_score_codex":0.000010490646,"about_ca_system_score_gemma":0.00004468823,"threshold_uncertainty_score":0.99999577},"labels":[],"label_agreement":null},{"id":"W4379988463","doi":"10.1101/2023.06.08.544212","title":"A Pandemic-Scale Ancestral Recombination Graph for SARS-CoV-2","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Discovery Centre; Public Health Agency of Canada","funders":"Robertson Foundation; Wellcome Trust","keywords":"Phylogenetic tree; Recombination; Biology; Phylogenetics; Evolutionary biology; Python (programming language); Genetics; Pedigree chart; Genome; Computational biology; Gene; Computer science","score_opus":0.027374108388213983,"score_gpt":0.2958655127465526,"score_spread":0.2684914043583386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379988463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9430316,0.0009080678,0.052685183,0.00011136405,0.0018777605,0.00080166827,0.0003152899,0.0002642136,0.0000048350603],"genre_scores_gemma":[0.9906702,0.0006579947,0.0071735918,0.00010637605,0.0007072592,0.000491618,0.0000076050396,0.00016368885,0.000021688296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979521,0.00003897268,0.00039380943,0.0009400751,0.0001721798,0.0005028468],"domain_scores_gemma":[0.99858314,0.000020854837,0.00018528618,0.00083840225,0.0002718153,0.00010051372],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041901928,0.0004242162,0.00034962816,0.0001574497,0.000099072684,0.000094091076,0.0004139407,0.00064046023,0.0000017768581],"category_scores_gemma":[0.00013305448,0.0004988958,0.0002534627,0.00020711774,0.00006055771,0.000006037931,0.00027933746,0.00030048832,0.000014122838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029616727,0.000045117868,0.0032729963,0.0002560739,0.00010288616,0.0000026409577,0.0000037051454,0.00027341454,0.99392027,0.00003339834,0.0020543002,0.0000055722367],"study_design_scores_gemma":[0.0005667416,0.00011347523,0.02147335,0.00012275498,0.00007233265,2.3106718e-8,0.0000021255105,0.0004187461,0.96695083,0.000016138518,0.009629437,0.00063407054],"about_ca_topic_score_codex":0.000024367018,"about_ca_topic_score_gemma":0.000020647838,"teacher_disagreement_score":0.047638558,"about_ca_system_score_codex":0.00005444068,"about_ca_system_score_gemma":0.00020497084,"threshold_uncertainty_score":0.99974626},"labels":[],"label_agreement":null},{"id":"W4380077595","doi":"10.1038/s42003-023-04974-0","title":"Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity","year":2023,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"Common Fund; National Human Genome Research Institute; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; Genome Canada; Ontario Genomics; NIH Office of the Director; University of California, Davis","keywords":"Cas9; CRISPR; Genome; Genome editing; Biology; Sanger sequencing; Genetics; Computational biology; Mutagenesis; Context (archaeology); Whole genome sequencing; DNA sequencing; Gene; Mutation","score_opus":0.03142881984335195,"score_gpt":0.37550278159896244,"score_spread":0.3440739617556105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380077595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9795042,0.0026773864,0.01536359,0.0012615618,0.00008712188,0.00032027188,0.00037467887,0.000038994553,0.00037218092],"genre_scores_gemma":[0.99071836,0.0007283348,0.0047885594,0.00007798124,0.00007294286,0.00017188821,0.0030081754,0.000015420914,0.00041832196],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999104,0.00011509785,0.00021730777,0.0002715886,0.000028553324,0.00026340652],"domain_scores_gemma":[0.9986223,0.00011458484,0.00006322196,0.0010828823,0.00006916798,0.00004786067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003342133,0.000117939264,0.00021489443,0.0002413745,0.000098146505,0.0000091556285,0.00056665734,0.00017897952,0.000008362661],"category_scores_gemma":[0.00017480155,0.0001271454,0.00013231343,0.0006518841,0.00009459579,0.0000026955001,0.00035158615,0.000101597405,0.000013506065],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002728848,0.000055200137,0.0149353305,0.000010513126,0.00019262743,3.5369962e-7,0.0000786043,0.0011552008,0.981764,0.000086436805,0.0006111207,0.0010833055],"study_design_scores_gemma":[0.0013841518,0.00040414173,0.40721235,0.000011387313,0.00024918775,0.00000731856,0.0002916471,0.024644066,0.048049115,0.0006382316,0.51642483,0.00068357267],"about_ca_topic_score_codex":0.00003551481,"about_ca_topic_score_gemma":0.0005281776,"teacher_disagreement_score":0.9337149,"about_ca_system_score_codex":0.000018411058,"about_ca_system_score_gemma":0.000031645493,"threshold_uncertainty_score":0.5184839},"labels":[],"label_agreement":null},{"id":"W4380086369","doi":"10.1182/blood.2022019333","title":"Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; European Hematology Association","keywords":"Electroporation; Ex vivo; Genome editing; Biology; Cell biology; Haematopoiesis; Progenitor cell; Gene delivery; Stem cell; Genetic enhancement; Molecular biology; In vivo; Gene; CRISPR; Genetics","score_opus":0.007610037621833489,"score_gpt":0.2594565427466761,"score_spread":0.25184650512484263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380086369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989023,0.00047922027,0.00024564686,0.000022550506,0.0001085024,0.00008075025,0.000011098066,0.000023198483,0.00012672062],"genre_scores_gemma":[0.999284,0.000052509975,0.00027829234,0.000013310585,0.00020646752,0.000007250504,0.000012811693,0.000017946919,0.0001274033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993383,0.000012584159,0.00016303251,0.00020153173,0.00008990389,0.00019461292],"domain_scores_gemma":[0.9996887,0.0000084088415,0.000036931844,0.00018028848,0.000026116722,0.00005954891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011881717,0.00009638495,0.000115474264,0.00003408404,0.000046543024,0.0000115306175,0.000081333754,0.000056496443,0.000008312857],"category_scores_gemma":[0.000015475343,0.00009807816,0.000042471114,0.00008233205,0.00004069666,7.900738e-7,0.00010637553,0.000032996122,0.0000050406093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002227055,0.00006497466,0.0006312056,0.00006541386,0.000025366671,0.0000039617757,0.00013519346,0.0008336704,0.9979397,0.000013655579,0.00019233277,0.00009228122],"study_design_scores_gemma":[0.00052552496,0.00008951074,0.0010946271,0.000019478743,0.000030965875,0.000009262134,0.00012243916,0.00024234715,0.997398,0.0000067389087,0.00035634974,0.0001047321],"about_ca_topic_score_codex":0.0000045192487,"about_ca_topic_score_gemma":0.0000029152243,"teacher_disagreement_score":0.00059132325,"about_ca_system_score_codex":0.0000013299898,"about_ca_system_score_gemma":0.000008353703,"threshold_uncertainty_score":0.39995113},"labels":[],"label_agreement":null},{"id":"W4380204664","doi":"10.1093/mutage/gead012","title":"Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology","year":2023,"lang":"en","type":"article","venue":"Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institutes of Health; National Institute of Environmental Health Sciences; Royal Society; Cancer Research UK","keywords":"Computational biology; Genome editing; Genomics; Precision medicine; Mutagenesis; Biology; Biotechnology; Genetics; Gene; Mutation; Genome","score_opus":0.04387679517856014,"score_gpt":0.28588447469181594,"score_spread":0.2420076795132558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380204664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9702819,0.0016213747,0.017926807,0.009490187,0.00026565505,0.00031489736,0.000020932697,0.000020713624,0.000057517624],"genre_scores_gemma":[0.9910497,0.0008986716,0.0007851044,0.0026346059,0.0006884385,0.00007607582,0.00005603727,0.000045888875,0.0037654957],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998792,0.00007647114,0.00022238065,0.00039067195,0.00019785773,0.0003206398],"domain_scores_gemma":[0.9991475,0.000073649826,0.00007464859,0.0005690194,0.00006571812,0.00006949245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038691616,0.00020092905,0.0001795978,0.000038921542,0.0002330431,0.000024746425,0.00028734573,0.00015141611,0.000077563505],"category_scores_gemma":[0.00008358309,0.00013356634,0.00013495474,0.00023302824,0.00009925555,0.0000018635717,0.00023931901,0.00009166507,0.000017877577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014584127,0.0000054715315,0.00014753007,0.00001827508,0.00006420733,0.0000019122228,0.0008348157,0.07518452,0.868328,0.000007548456,0.050858792,0.00453439],"study_design_scores_gemma":[0.0002924819,0.0001970516,0.001435823,0.000021037586,0.000058435136,0.000007769092,0.0011655117,0.09697645,0.87661344,0.000012680283,0.022988325,0.00023099396],"about_ca_topic_score_codex":0.00003485871,"about_ca_topic_score_gemma":0.00007605453,"teacher_disagreement_score":0.027870469,"about_ca_system_score_codex":0.00007362364,"about_ca_system_score_gemma":0.000053712916,"threshold_uncertainty_score":0.5446677},"labels":[],"label_agreement":null},{"id":"W4380319279","doi":"10.1016/j.healun.2023.06.001","title":"Immunomodulation of the donor lung with CRISPR-mediated activation of IL-10 expression","year":2023,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Toronto General Hospital; Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; University Health Network Foundation; Canadian Society of Transplantation; University of Toronto","keywords":"CRISPR; Downregulation and upregulation; Lung; In vivo; Immunology; Immunosuppression; Transplantation; Ex vivo; Biology; Cancer research; Lung transplantation; Cytokine; Medicine; Gene; Internal medicine; Genetics","score_opus":0.005015684283398284,"score_gpt":0.2627902738665811,"score_spread":0.25777458958318283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380319279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98973143,0.00020995403,0.009757144,0.00015037593,0.00004527697,0.00008066561,0.0000061935793,0.0000019192623,0.000017062603],"genre_scores_gemma":[0.9992748,0.0004975432,0.00013291209,0.000008523842,0.000035067354,8.305524e-7,0.000021743353,0.000005500237,0.000023105287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995858,0.00004366565,0.00016920494,0.0000395935,0.000109203385,0.000052527797],"domain_scores_gemma":[0.99969333,0.00003486128,0.0001122781,0.00007547806,0.00007157286,0.000012460522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022846414,0.000048218564,0.00007183283,0.00003568792,0.000040127245,0.0000031408003,0.000050734598,0.000034388744,0.0000029138007],"category_scores_gemma":[0.000010820036,0.000026556125,0.000029942656,0.00008931382,0.000025424795,0.000007883289,0.0000058307733,0.000049784187,1.07203334e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038851186,0.0000071387576,0.0034017928,0.00007650714,0.00002350536,1.2408765e-7,0.0004980392,0.0061461367,0.98915803,0.0000017682823,0.00017025885,0.00012820677],"study_design_scores_gemma":[0.00042207414,0.00012007376,0.1815364,0.00012321754,0.00005469273,0.000023426885,0.00011400251,0.0011846247,0.81629497,0.000005840045,0.00008889443,0.000031755717],"about_ca_topic_score_codex":0.000007807807,"about_ca_topic_score_gemma":0.000004944113,"teacher_disagreement_score":0.17813462,"about_ca_system_score_codex":0.0000027845251,"about_ca_system_score_gemma":0.00001957678,"threshold_uncertainty_score":0.10829273},"labels":[],"label_agreement":null},{"id":"W4380871976","doi":"10.1016/j.crmeth.2023.100464","title":"Rapid, scalable, combinatorial genome engineering by marker-less enrichment and recombination of genetically engineered loci in yeast","year":2023,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"National Institute of General Medical Sciences; Army Research Office; Natural Sciences and Engineering Research Council of Canada; Faculty of Arts and Sciences; National Institutes of Health; Canada Research Chairs; York University; Concordia University; Welch Foundation; Canada Foundation for Innovation; Fonds de recherche du Québec – Nature et technologies; Harvard University; University of Washington; Ministère de l'Économie, de l’Innovation et des Exportations du Québec; University of Toronto; New York University","keywords":"CRISPR; Genome editing; Biology; Genetics; Computational biology; Merge (version control); Cas9; Genome; Recombination; Homologous recombination; Genome engineering; Gene; Yeast; Locus (genetics); Computer science","score_opus":0.00884339042010853,"score_gpt":0.2915578569617895,"score_spread":0.282714466541681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380871976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92555124,0.0035575747,0.06927975,0.000020416124,0.0006889278,0.0002722551,0.0000073251895,0.000032791642,0.000589713],"genre_scores_gemma":[0.9699734,0.0010113806,0.028366866,0.0000072998187,0.00007392969,0.000035662502,0.00015075164,0.00004049066,0.00034021956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987007,0.000068170724,0.00043980748,0.00036816575,0.00013403807,0.00028913416],"domain_scores_gemma":[0.9994236,0.000035545425,0.000089632966,0.0002997956,0.000054208456,0.00009716787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011986628,0.0001703526,0.0002369613,0.00012785921,0.00002028753,0.000014388017,0.00008237508,0.00016313948,0.000011004937],"category_scores_gemma":[0.00017857857,0.00019153976,0.000055652137,0.00026552068,0.000025883466,0.0000033491942,0.0001259205,0.00009814002,6.1421326e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000129263735,0.000045137924,0.0006406193,0.00011317645,0.000021512305,0.000016733009,0.0000429006,0.003026473,0.9846718,0.000016415539,0.0002657191,0.011126638],"study_design_scores_gemma":[0.0007251699,0.00015520718,0.018109074,0.000020659374,0.0000249322,0.00003108597,0.000059551596,0.00512121,0.947885,0.000113626535,0.027425084,0.00032940527],"about_ca_topic_score_codex":0.000009210894,"about_ca_topic_score_gemma":5.184152e-7,"teacher_disagreement_score":0.044422157,"about_ca_system_score_codex":0.000020033927,"about_ca_system_score_gemma":0.000030419102,"threshold_uncertainty_score":0.78107643},"labels":[],"label_agreement":null},{"id":"W4380996898","doi":"10.3390/jof9060673","title":"Unanticipated Large-Scale Deletion in Fusarium graminearum Genome Using CRISPR/Cas9 and Its Impact on Growth and Virulence","year":2023,"lang":"en","type":"article","venue":"Journal of Fungi","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Biology; Virulence; Gene; Fusarium; Genetics; Genome; Mutant; Transmembrane domain","score_opus":0.012341262912161395,"score_gpt":0.3302377433384102,"score_spread":0.3178964804262488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380996898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950516,0.0028915703,0.0018189256,0.000057408462,0.00009079593,0.00005356515,0.000019194214,0.0000038262447,0.000013118143],"genre_scores_gemma":[0.99755186,0.0020208857,0.0002417464,0.000032750748,0.00011365552,5.853475e-7,0.000011952194,0.0000130601165,0.0000134854245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935174,0.000024824434,0.00019948924,0.0001229817,0.000093935436,0.00020702886],"domain_scores_gemma":[0.99971575,0.000012873824,0.000070579896,0.00006430079,0.000052700863,0.00008378684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024822203,0.0001027532,0.0001415888,0.00014285483,0.000031995853,0.000020101445,0.0000547926,0.00007972204,0.0000020067812],"category_scores_gemma":[0.00004486621,0.00008634613,0.00004495101,0.00015260508,0.000011549271,0.0000066948796,0.00004452979,0.00011118816,0.0000010755749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007019363,0.000022553713,0.0066133724,0.00002891848,0.0000209393,0.000027406404,0.000096505566,0.002484643,0.9902863,0.0000038931967,0.000014157514,0.00033110316],"study_design_scores_gemma":[0.0012086362,0.0009432684,0.34482694,0.000068134366,0.000044875913,0.0002761324,0.00018762235,0.028777974,0.6230989,0.000039608247,0.00026929908,0.0002585915],"about_ca_topic_score_codex":0.000007871678,"about_ca_topic_score_gemma":0.0000031005693,"teacher_disagreement_score":0.36718738,"about_ca_system_score_codex":0.000011416525,"about_ca_system_score_gemma":0.000022835184,"threshold_uncertainty_score":0.3521093},"labels":[],"label_agreement":null},{"id":"W4381053620","doi":"10.1101/2023.06.16.545157","title":"A scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"CRISPR; Scalability; Computational biology; Genetic screen; DNA damage; Cas9; DNA; Biology; Computer science; Genetics; Gene; Phenotype","score_opus":0.017529619631131574,"score_gpt":0.263212188044613,"score_spread":0.2456825684134814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381053620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9522742,0.0010097106,0.044093303,0.000058555925,0.00088330137,0.0009887661,0.00052452093,0.00015576159,0.000011856599],"genre_scores_gemma":[0.9811644,0.00013090049,0.017515814,0.000047904956,0.00061693444,0.0002606169,0.000008254996,0.00023710816,0.000018074274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969323,0.00003156379,0.0007495349,0.0011854026,0.0003412509,0.00075993256],"domain_scores_gemma":[0.9973106,0.00005962172,0.0003401869,0.0015288489,0.0004890498,0.00027169962],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005048899,0.00061979605,0.00067008013,0.00023013963,0.00011985,0.00008931746,0.000695869,0.00074214453,0.000007871756],"category_scores_gemma":[0.00030800456,0.00071139296,0.00035153073,0.0003261234,0.00013739346,0.0000044663625,0.0008374735,0.00039102873,0.000013327851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005507333,0.00010546664,0.0006379942,0.0008064488,0.0002155696,0.000007133697,0.00000862593,0.007579844,0.9896532,0.000041062158,0.0008862819,0.0000032938408],"study_design_scores_gemma":[0.0007494799,0.00011926676,0.00932835,0.00034583083,0.0001552084,5.627497e-8,0.000008401125,0.006001726,0.9805724,0.000002313679,0.0019620568,0.0007549346],"about_ca_topic_score_codex":0.00004711197,"about_ca_topic_score_gemma":0.00000427896,"teacher_disagreement_score":0.028890168,"about_ca_system_score_codex":0.00009290334,"about_ca_system_score_gemma":0.00036818415,"threshold_uncertainty_score":0.9995337},"labels":[],"label_agreement":null},{"id":"W4381166430","doi":"10.3390/ijms241210266","title":"A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Newcastle University; Company of Biologists; National Centre for the Replacement, Refinement and Reduction of Animals in Research; Cystic Fibrosis Trust; Cystic Fibrosis Foundation","keywords":"Induced pluripotent stem cell; Genome editing; CRISPR; Transcription activator-like effector nuclease; Zinc finger nuclease; Cas9; Biology; Computational biology; Cell sorting; Mutation; ΔF508; Gene; Genetics; Embryonic stem cell; Cell","score_opus":0.014576480121669058,"score_gpt":0.2956252247852787,"score_spread":0.28104874466360963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381166430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7885559,0.0006324016,0.21035801,0.00006668022,0.00022569989,0.000071991264,0.000008850464,0.0000026616592,0.00007778958],"genre_scores_gemma":[0.9853451,0.00003617375,0.01442346,0.000036465237,0.00012477986,0.0000036386486,0.00000686316,0.0000067573656,0.000016743154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915004,0.000018282928,0.00024522288,0.00014419497,0.0003250659,0.00011717],"domain_scores_gemma":[0.9995006,0.000015682192,0.00017028964,0.000061369945,0.00020349608,0.000048605176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051532214,0.000073632764,0.00009717882,0.00014585032,0.00004529104,0.0000299208,0.00029130784,0.00003453053,0.0000014811766],"category_scores_gemma":[0.00001690951,0.00006460398,0.00010149745,0.00008668624,0.00008598632,0.0000027640688,0.000056218098,0.00003664453,1.2820821e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012969853,0.00002524814,0.00003217809,0.000012167778,0.00002076119,0.00000412462,0.00003335664,0.28489253,0.7143505,0.000010827421,0.000055310247,0.00055002345],"study_design_scores_gemma":[0.0005953339,0.0003060963,0.000089835514,0.000016959328,0.000011860516,0.000013290269,0.00018208532,0.041678987,0.9568934,0.000009176082,0.00013891961,0.000064078056],"about_ca_topic_score_codex":0.0000013554057,"about_ca_topic_score_gemma":9.7940784e-8,"teacher_disagreement_score":0.24321355,"about_ca_system_score_codex":0.0000071380464,"about_ca_system_score_gemma":0.000055029403,"threshold_uncertainty_score":0.26344737},"labels":[],"label_agreement":null},{"id":"W4381192959","doi":"10.1089/hum.2023.016","title":"Genome Editing in Ferret Airway Epithelia Mediated by CRISPR/Nucleases Delivered with Amphiphilic Shuttle Peptides","year":2023,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Feldan (Canada)","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Genome editing; Biology; Green fluorescent protein; Reporter gene; Cell biology; Gene delivery; Transgene; Cre recombinase; In vitro; Genetic enhancement; Molecular biology; CRISPR; Gene; Genetics; Gene expression; Genetically modified mouse","score_opus":0.012422823056447676,"score_gpt":0.27903850460150276,"score_spread":0.2666156815450551,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381192959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962268,0.0027770603,0.00033201592,0.00008877534,0.00006399975,0.00021584959,0.000064306296,0.000081103804,0.00015012665],"genre_scores_gemma":[0.9967006,0.0014435961,0.0001374611,0.00015772073,0.00031775451,0.000047029032,0.0007812796,0.000071404786,0.0003431456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987778,0.000042192678,0.00022045038,0.00039968456,0.0001562805,0.0004035851],"domain_scores_gemma":[0.99945974,0.000015121325,0.00005339685,0.00033273874,0.0000458499,0.00009314548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016447729,0.00023102,0.00019107059,0.00010568105,0.00010744262,0.00002972819,0.00022557679,0.00010845801,0.00010145079],"category_scores_gemma":[0.000016671596,0.0002129305,0.00006032194,0.00022788596,0.00006525991,0.0000048907386,0.000056634075,0.00009987704,0.000041692998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058670183,0.000040573443,0.0019474308,0.0000102284375,0.000049143626,0.000014539177,0.00023223834,0.00094639807,0.9945727,0.0000031992324,0.0014913698,0.00063351484],"study_design_scores_gemma":[0.0022514365,0.0007694526,0.052297257,0.000030271203,0.000011887012,0.000017608947,0.0003261057,0.00024964559,0.92551106,0.00005656263,0.01790952,0.00056918786],"about_ca_topic_score_codex":0.000065346,"about_ca_topic_score_gemma":0.00011435152,"teacher_disagreement_score":0.06906163,"about_ca_system_score_codex":0.000018387576,"about_ca_system_score_gemma":0.000024453226,"threshold_uncertainty_score":0.86830544},"labels":[],"label_agreement":null},{"id":"W4381327254","doi":"10.1080/15265161.2023.2207513","title":"Translational Justice in Human Gene Editing: Bringing End User Engagement and Policy Together","year":2023,"lang":"en","type":"letter","venue":"The American Journal of Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute","keywords":"Genome editing; Public engagement; Economic Justice; Corporate governance; Human genome; User engagement; Political science; Public policy; Sociology; Public relations; Genome; World Wide Web; Biology; Genetics; Gene; Computer science; Law; Management","score_opus":0.039219674505029715,"score_gpt":0.3693222439803856,"score_spread":0.3301025694753559,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381327254","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34985483,0.0025039024,0.009676786,0.6366257,0.00077955227,0.00023095103,0.000065245586,0.000017080612,0.00024593074],"genre_scores_gemma":[0.80581456,0.0033920982,0.0035086216,0.15848213,0.027774882,0.000008872927,0.00010797049,0.0001921188,0.0007187487],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99871576,0.00018904687,0.00036876663,0.00017705928,0.0002887882,0.00026057],"domain_scores_gemma":[0.9992206,0.00013115222,0.00032541036,0.0001953828,0.0000834261,0.000044037428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010236274,0.00018911752,0.00026572568,0.0001962431,0.00009167573,0.00003503415,0.00027477418,0.00017686545,0.0000048530683],"category_scores_gemma":[0.000124771,0.00015418677,0.0001068832,0.00017767778,0.00039285628,0.0000026920513,0.00008576201,0.001489698,9.0178617e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002971448,0.0001273261,0.0021973893,0.0009823381,0.0022860758,0.0011173941,0.010426428,0.021444809,0.6130303,0.00041289095,0.30683205,0.04084582],"study_design_scores_gemma":[0.0017406986,0.0017137906,0.009542192,0.00059864606,0.00088697387,0.0008687124,0.00299027,0.00028324308,0.06820194,0.0008500045,0.91098523,0.0013382905],"about_ca_topic_score_codex":0.00011945377,"about_ca_topic_score_gemma":0.00002997795,"teacher_disagreement_score":0.6041532,"about_ca_system_score_codex":0.000019400377,"about_ca_system_score_gemma":0.00014391686,"threshold_uncertainty_score":0.6472079},"labels":[],"label_agreement":null},{"id":"W4381327314","doi":"10.1080/15265161.2023.2207544","title":"Disclosing Reproductive Genetic Carrier Status: What about the Donor?","year":2023,"lang":"en","type":"letter","venue":"The American Journal of Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Work (physics); Internet privacy; Psychology; Computer science; Engineering","score_opus":0.026377753956897742,"score_gpt":0.3429186238495831,"score_spread":0.3165408698926854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381327314","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16293502,0.027012538,0.0044404026,0.80140644,0.0036323916,0.0003856341,0.000102915605,0.000023973853,0.00006067942],"genre_scores_gemma":[0.21319109,0.15133913,0.003002565,0.56625557,0.06241781,0.00004496037,0.00020016251,0.0006909035,0.0028577978],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99771917,0.00038508468,0.00053283165,0.00036577493,0.0004960442,0.0005010776],"domain_scores_gemma":[0.99749905,0.00020532848,0.000864359,0.0010268544,0.00032660802,0.000077807104],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00095839927,0.000333244,0.0004385799,0.00008767387,0.00019464541,0.00019248527,0.00083437224,0.00026047835,0.0000047067397],"category_scores_gemma":[0.00031847841,0.00019068042,0.0003534055,0.0002944433,0.0015792866,0.000007208225,0.00022376592,0.002454819,0.0000061208443],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035332656,0.00003670985,0.0004271344,0.0001761726,0.0023893185,0.00033444917,0.006690303,0.007092645,0.03418595,0.000013790554,0.8549768,0.09332344],"study_design_scores_gemma":[0.00024661858,0.0010478646,0.0014445871,0.0003245706,0.00044891433,0.0005640267,0.0075594806,0.000034330806,0.014728048,0.00028179958,0.972737,0.0005827576],"about_ca_topic_score_codex":0.000121404104,"about_ca_topic_score_gemma":0.000023510482,"teacher_disagreement_score":0.23515087,"about_ca_system_score_codex":0.000041039566,"about_ca_system_score_gemma":0.0003057213,"threshold_uncertainty_score":0.9998466},"labels":[],"label_agreement":null},{"id":"W4381327441","doi":"10.1080/15265161.2023.2215608","title":"The Intrinsic Value of Public Deliberation in the Governance of Human Genome Editing","year":2023,"lang":"en","type":"letter","venue":"The American Journal of Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics","funders":"","keywords":"Deliberation; Genome editing; Corporate governance; Value (mathematics); Public engagement; Political science; Sociology; Public relations; Genome; Computer science; Biology; Genetics; Business; Politics; Law; Gene","score_opus":0.03069468918025625,"score_gpt":0.3350746022936234,"score_spread":0.30437991311336715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381327441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5479668,0.004349042,0.0022511021,0.44438672,0.0006312089,0.00023693175,0.00004921083,0.0000046755786,0.0001242988],"genre_scores_gemma":[0.973433,0.003679021,0.00016830357,0.019160151,0.0034226775,0.0000044733583,0.00002619194,0.000038894843,0.00006728046],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982801,0.00038259898,0.0005908375,0.00011225899,0.00042235595,0.0002118122],"domain_scores_gemma":[0.9978027,0.00029323876,0.0012394284,0.00040704524,0.00024007923,0.00001755024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022259825,0.00014368743,0.00028206263,0.000051328752,0.00009425672,0.000031840937,0.00085123495,0.00014800928,9.455944e-7],"category_scores_gemma":[0.0003698365,0.00007806387,0.00017023648,0.00027329102,0.00077642413,0.000003192332,0.00010077538,0.0012839589,4.6552768e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024906892,0.00016877586,0.001059711,0.00066380354,0.0018111039,0.00015207594,0.008179461,0.008902253,0.65226233,0.0032823628,0.22083916,0.10242987],"study_design_scores_gemma":[0.0020689336,0.0091275945,0.059549473,0.0011636973,0.00075122516,0.0008485323,0.015531775,0.00040490643,0.12465935,0.0038153154,0.7803992,0.0016800112],"about_ca_topic_score_codex":0.00008694979,"about_ca_topic_score_gemma":0.00006744042,"teacher_disagreement_score":0.55956,"about_ca_system_score_codex":0.000019353034,"about_ca_system_score_gemma":0.00014333484,"threshold_uncertainty_score":0.55782336},"labels":[],"label_agreement":null},{"id":"W4381612060","doi":"10.1089/crispr.2023.0007","title":"Rapid and Technically Simple Detection of SARS-CoV-2 Variants Using CRISPR Cas12 and Cas13","year":2023,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Centre National en Électrochimie et en Technologies Environnementales; Collège Shawinigan; Centre hospitalier de l'Université Laval; Université Laval; Héma-Québec; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Loop-mediated isothermal amplification; Sanger sequencing; Amplicon; Computational biology; Pipeline (software); Computer science; Palindrome; Nanopore sequencing; Biology; Virology; Mutation; Genetics; Polymerase chain reaction; Genome; Gene; Operating system","score_opus":0.03159809360156925,"score_gpt":0.34597362768000106,"score_spread":0.31437553407843183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381612060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96434456,0.0018728153,0.03338736,0.000116661184,0.0001305274,0.000082037426,0.0000064414876,0.0000117969685,0.00004781656],"genre_scores_gemma":[0.99781424,0.0014855056,0.0004102171,0.00006095125,0.00019093082,0.0000017479782,0.0000020590692,0.0000188354,0.000015495927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992788,0.0000500537,0.00021757503,0.00014737427,0.00010295236,0.00020327793],"domain_scores_gemma":[0.9996126,0.000022231807,0.00007855374,0.00017518288,0.00006227689,0.00004911529],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047566104,0.000111184825,0.00012812897,0.000067088986,0.00017182343,0.00003665767,0.00010362944,0.000090970105,0.0000032347307],"category_scores_gemma":[0.000098329,0.00008562211,0.00004834549,0.00012276994,0.00007727426,0.0000053462677,0.00011787036,0.00016181453,9.277962e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003098798,0.000006350026,0.00015557547,0.00001579242,0.000035813824,0.000007818263,0.00008001326,0.0001370808,0.9914436,0.0000049331707,0.00033328964,0.007748793],"study_design_scores_gemma":[0.00039023062,0.00017798235,0.0055251117,0.000017393826,0.00005393627,0.0011848948,0.00020339429,0.0027378153,0.98565793,0.0002501329,0.0036734059,0.00012777792],"about_ca_topic_score_codex":0.000032532604,"about_ca_topic_score_gemma":0.000022942233,"teacher_disagreement_score":0.033469714,"about_ca_system_score_codex":0.000007145938,"about_ca_system_score_gemma":0.000025978203,"threshold_uncertainty_score":0.34915683},"labels":[],"label_agreement":null},{"id":"W4381797951","doi":"10.1525/elementa.2022.00145","title":"Gene-editing technologies for developing climate resilient rice crops in sub-Saharan Africa: Political priorities and space for responsible innovation","year":2023,"lang":"en","type":"article","venue":"Elementa Science of the Anthropocene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"New Partnership for Africa's Development; Japan International Cooperation Agency; Consortium of International Agricultural Research Centers; Alliance for a Green Revolution in Africa","keywords":"Context (archaeology); Productivity; Food security; Green Revolution; Agriculture; Natural resource economics; Developing country; Biotechnology; Agricultural economics; Vulnerability (computing); Climate change; Business; Economic growth; Geography; Biology; Economics; Ecology","score_opus":0.022172648059602944,"score_gpt":0.34721123664901204,"score_spread":0.3250385885894091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381797951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933135,0.0005073858,0.0032819232,0.002266306,0.0001618633,0.00037240185,0.00004327292,0.000020170299,0.00003317827],"genre_scores_gemma":[0.98956674,0.00040501507,0.009896739,0.000019498164,0.00003481336,0.000043225908,0.000009601758,0.000008258778,0.000016133978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990124,0.000008994876,0.00020618197,0.00024194572,0.00012669983,0.00040375695],"domain_scores_gemma":[0.9996101,0.000032736953,0.000058629845,0.00017359422,0.00011121226,0.000013694137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007048829,0.0000792698,0.00008957927,0.00017308768,0.00022809481,0.000023871304,0.00021597832,0.00004137941,2.3063214e-7],"category_scores_gemma":[0.0005780028,0.00006660075,0.000021369227,0.00077447225,0.00041038904,0.000009936258,0.00027270097,0.00003310322,1.6224003e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027279075,0.0000068494987,0.001979298,0.00007232786,0.0000034966915,1.4715783e-7,0.0000337156,0.00005976916,0.9930543,0.0036143758,0.00031651178,0.0008319507],"study_design_scores_gemma":[0.00028950188,0.0000928089,0.010512306,0.000043942706,0.0000041032868,0.000001867854,0.0009992195,0.00040381888,0.9859653,0.0010222024,0.0005809556,0.00008396078],"about_ca_topic_score_codex":0.000007527004,"about_ca_topic_score_gemma":0.000014313771,"teacher_disagreement_score":0.008533008,"about_ca_system_score_codex":0.000033092147,"about_ca_system_score_gemma":0.00011457374,"threshold_uncertainty_score":0.27158996},"labels":[],"label_agreement":null},{"id":"W4381856283","doi":"10.1101/2023.06.21.545895","title":"Utilizing a dual endogenous reporter system to identify functional regulators of aberrant stem cell and differentiation activity in colorectal cancer","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; National Institutes of Health; Nemzeti Kutatási Fejlesztési és Innovációs Hivatal; Harvard Digestive Diseases Center, Harvard University; Dana-Farber/Harvard Cancer Center; U.S. Department of Defense","keywords":"Biology; Stem cell; Cancer stem cell; Cellular differentiation; Cancer research; Epigenetics; Endogeny; Cell growth; Cell biology; Computational biology; Genetics; Gene","score_opus":0.021207065188106847,"score_gpt":0.255765455487981,"score_spread":0.2345583902998742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381856283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951224,0.0007172372,0.0022807,0.000016497183,0.0010661401,0.00056680245,0.00016541184,0.000062112806,0.0000027422275],"genre_scores_gemma":[0.99917513,0.000116931675,0.00016993082,0.000006152684,0.00021940624,0.00022653135,0.0000014804951,0.00007779179,0.000006615462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981403,0.00006774536,0.0004512364,0.00077697774,0.00024575024,0.00031803112],"domain_scores_gemma":[0.99897546,0.000016937553,0.00026729397,0.00043727746,0.00016787606,0.00013517535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034882594,0.00032467235,0.00039847885,0.00021023938,0.000053523312,0.000047648202,0.00012317688,0.00037359295,0.0000027057386],"category_scores_gemma":[0.000024396824,0.00036881847,0.00010010866,0.00020861631,0.00003424653,0.0000060255265,0.00038320373,0.00020907992,0.0000016783581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076207034,0.000044940494,0.021763975,0.00075410784,0.00009538662,0.000022021773,0.000022414346,0.0016970409,0.97548026,0.000006758919,0.000032518048,0.000004343025],"study_design_scores_gemma":[0.00022190674,0.000035392353,0.37570706,0.00017876558,0.00004212455,9.782687e-8,0.000011911482,0.00040998173,0.62314284,6.419819e-8,0.000025597794,0.00022427333],"about_ca_topic_score_codex":0.00016046944,"about_ca_topic_score_gemma":0.00005559854,"teacher_disagreement_score":0.35394308,"about_ca_system_score_codex":0.00013289214,"about_ca_system_score_gemma":0.00021051298,"threshold_uncertainty_score":0.9998764},"labels":[],"label_agreement":null},{"id":"W4381889474","doi":"10.1101/2023.06.23.546257","title":"Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers <i>in trans</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Novo Nordisk Fonden; Lietuvos Mokslo Taryba; Novo Nordisk; H. Lundbeck A/S; Lundbeckfonden; Eidgenössische Technische Hochschule Zürich; Oxford Nanopore Technologies; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Regional Development Fund; Deutsche Forschungsgemeinschaft; European Commission","keywords":"Plasmid; CRISPR; Biology; Horizontal gene transfer; Genetics; Trans-activating crRNA; Gene; Ribonucleoprotein; Cas9; Computational biology; RNA; Genome","score_opus":0.012471437800141354,"score_gpt":0.25779460452974046,"score_spread":0.2453231667295991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381889474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93342096,0.011225344,0.04584768,0.0003423243,0.006398891,0.001593995,0.0006369767,0.00045968976,0.000074124415],"genre_scores_gemma":[0.9965919,0.001677835,0.00047774686,0.0001323691,0.000535513,0.00018511032,0.0000067522574,0.00026742765,0.00012532434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967869,0.00010342628,0.0006496734,0.0013350181,0.0003105347,0.00081443053],"domain_scores_gemma":[0.9979251,0.00003433604,0.00022203039,0.001240791,0.00026820024,0.00030955047],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048051935,0.00072715036,0.00065518834,0.00024777965,0.00008228958,0.0001918304,0.0006561068,0.0008974648,0.000018004714],"category_scores_gemma":[0.00014316193,0.0008596031,0.0001935655,0.00038120188,0.000108385,0.00001006389,0.00047393647,0.00065946724,0.000050601986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005455233,0.000055211414,0.0023492312,0.0005134882,0.00020745584,0.00005606473,0.000027827731,0.0034387382,0.9845381,0.000018855468,0.008738837,0.0000016612597],"study_design_scores_gemma":[0.0008901884,0.00015783832,0.0044984063,0.00066471205,0.00010200418,1.2318965e-7,0.000023648232,0.0023076183,0.89541256,4.78021e-7,0.09466226,0.0012801441],"about_ca_topic_score_codex":0.00015417418,"about_ca_topic_score_gemma":0.000027057533,"teacher_disagreement_score":0.0891255,"about_ca_system_score_codex":0.00015937546,"about_ca_system_score_gemma":0.00024920146,"threshold_uncertainty_score":0.9993855},"labels":[],"label_agreement":null},{"id":"W4382247824","doi":"10.1016/j.cell.2023.05.041","title":"Discovery of deaminase functions by structure-based protein clustering","year":2023,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"Steno Diabetes Center Aarhus; National Key Research and Development Program of China; National Natural Science Foundation of China; Novo Nordisk Fonden; Chinese Academy of Sciences; China Postdoctoral Science Foundation; National Postdoctoral Program for Innovative Talents","keywords":"Biology; Cytosine deaminase; Cytidine deaminase; Computational biology; DNA; Cytosine; Genetics; Protein structure; Cytidine; Substrate specificity; Gene; Biochemistry; Enzyme","score_opus":0.004559038332760087,"score_gpt":0.23782735305378136,"score_spread":0.23326831472102127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382247824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9444567,0.00020657034,0.054782826,0.000019615054,0.000088099805,0.0000966969,0.00007496014,0.0000144459855,0.00026007852],"genre_scores_gemma":[0.99624926,0.000006355114,0.00032505608,0.000014680372,0.000048605387,0.00001022904,0.00023314104,0.000013848371,0.0030988501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961144,0.000007616471,0.00008479913,0.00013206687,0.000049299073,0.00011480357],"domain_scores_gemma":[0.9997656,0.000003665918,0.000020998663,0.00017219062,0.000013886477,0.000023686105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000030011437,0.00006843545,0.000057284018,0.00002614247,0.00002234135,0.000008032358,0.0000622812,0.00005123186,0.000008205131],"category_scores_gemma":[0.000010399219,0.00006804211,0.000039299848,0.000079577665,0.000017902397,0.0000013071965,0.00003922959,0.000032403626,0.000005065187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010633749,0.000010353235,0.00009761268,0.000055176526,0.000004758106,6.8073035e-7,0.0000069941143,0.0050965315,0.9925403,8.439448e-7,0.0019513001,0.0002248002],"study_design_scores_gemma":[0.00021409935,0.00006962764,0.0003106747,0.000007392332,0.000005479608,4.447999e-7,0.000031890788,0.001166808,0.9930622,0.0000052513765,0.005047699,0.00007845715],"about_ca_topic_score_codex":0.000007650862,"about_ca_topic_score_gemma":0.000012962044,"teacher_disagreement_score":0.05445777,"about_ca_system_score_codex":0.0000034511563,"about_ca_system_score_gemma":0.000023446384,"threshold_uncertainty_score":0.27746767},"labels":[],"label_agreement":null},{"id":"W4382345003","doi":"10.1093/nar/gkad503","title":"Divergent directed evolution of a TetR-type repressor towards aromatic molecules","year":2023,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; PROTEO","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Biology; TetR; Computational biology; Repressor; Small molecule; Biochemistry; Synthetic biology; Allosteric regulation; Saccharomyces cerevisiae; Transcription factor; Yeast; Enzyme; Gene","score_opus":0.032137857060094394,"score_gpt":0.36772635160850764,"score_spread":0.3355884945484132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382345003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954975,0.00092815526,0.0011905023,0.000095681826,0.00014247114,0.00020699207,0.000012552304,0.00006844315,0.0018576477],"genre_scores_gemma":[0.99726677,0.00038248408,0.0008266334,0.0000049656846,0.00009564331,0.00002254283,0.000052477142,0.000027514772,0.0013209855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856037,0.00010479625,0.00019808077,0.00031021365,0.0004462361,0.00038029347],"domain_scores_gemma":[0.99917424,0.000024281087,0.00002743609,0.00047826377,0.0002024639,0.000093329436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054309715,0.000104604806,0.00013578331,0.00019523331,0.000085641695,0.00001492279,0.00027779842,0.00012427215,0.000052032243],"category_scores_gemma":[0.0007060968,0.00010070648,0.00007017739,0.0007655597,0.00010695282,0.0000027119934,0.0003444703,0.00013803308,0.00007818778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060051796,0.000041828745,0.0025065686,0.000073174764,0.000053208838,0.0000064008195,0.00012409943,0.0004866615,0.9863362,0.000057616864,0.0068890667,0.0033651306],"study_design_scores_gemma":[0.0006174818,0.0006805644,0.16498202,0.000078313424,0.00001910831,0.000009385804,0.00050290825,0.008226315,0.8104562,0.0006698262,0.013467908,0.00028993754],"about_ca_topic_score_codex":0.0000859194,"about_ca_topic_score_gemma":0.0000093155195,"teacher_disagreement_score":0.17587997,"about_ca_system_score_codex":0.0000354889,"about_ca_system_score_gemma":0.00009429302,"threshold_uncertainty_score":0.41066912},"labels":[],"label_agreement":null},{"id":"W4382371052","doi":"10.1101/2023.06.28.546942","title":"Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Endogeny; Induced pluripotent stem cell; HEK 293 cells; Computational biology; Biology; Protein engineering; Cell culture; Cytokinesis; Cell biology; Cell; Genetics; Cell division; Gene; Embryonic stem cell; Biochemistry; Enzyme","score_opus":0.04403229658882326,"score_gpt":0.3124642501693806,"score_spread":0.2684319535805574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382371052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97880995,0.008813296,0.009676777,0.0000777176,0.0011438731,0.0010849171,0.00021295494,0.00017738063,0.0000031506008],"genre_scores_gemma":[0.9894786,0.00059969944,0.008368019,0.00009094326,0.0009145952,0.00029472052,0.0000040764585,0.00023836362,0.0000109770035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972334,0.000061990686,0.00059137587,0.0011480171,0.00020282425,0.00076242187],"domain_scores_gemma":[0.9982714,0.00004662758,0.00024194088,0.0009641521,0.00033312952,0.00014275612],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006531176,0.0005845917,0.00059772114,0.00029830806,0.00019844412,0.000105659,0.00047434962,0.00035695868,0.000002657494],"category_scores_gemma":[0.00028576798,0.0007041474,0.00022884076,0.00022373149,0.00009974641,0.000008108801,0.00085085555,0.00038598382,0.000007662724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017596662,0.00003830861,0.005634586,0.0006174359,0.00022898996,0.000055908087,0.000037653543,0.0051701507,0.9880208,0.00004326343,0.0001318425,0.0000035040237],"study_design_scores_gemma":[0.0010707703,0.0000951913,0.011066215,0.0009377337,0.000229333,1.9867343e-7,0.00009173077,0.0042639934,0.9779108,0.000011327999,0.0027627745,0.0015599056],"about_ca_topic_score_codex":0.00010388802,"about_ca_topic_score_gemma":0.00002614852,"teacher_disagreement_score":0.010668673,"about_ca_system_score_codex":0.00019192291,"about_ca_system_score_gemma":0.00024011343,"threshold_uncertainty_score":0.999541},"labels":[],"label_agreement":null},{"id":"W4382397205","doi":"10.1038/d41586-023-02051-4","title":"How genetically modified mosquitoes could eradicate malaria","year":2023,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"World Federation of Science Journalists","funders":"","keywords":"Malaria; Gene drive; Biology; Genetically modified organism; Biotechnology; Gene; Virology; Genetics; CRISPR; Immunology","score_opus":0.007836938084488465,"score_gpt":0.28768897621949463,"score_spread":0.27985203813500614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382397205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97768295,0.0042345026,0.0060902284,0.00804179,0.0009406252,0.0002631528,0.00005699912,0.0001674332,0.0025223272],"genre_scores_gemma":[0.9933443,0.0003521043,0.000818992,0.00048446242,0.00048614285,0.000017200497,0.00016984636,0.000031477128,0.0042954884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914527,0.000014670338,0.00008762202,0.00030961444,0.0001580936,0.00028474652],"domain_scores_gemma":[0.9994961,0.000007993448,0.000020835352,0.00033301927,0.000050357223,0.00009167252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009259488,0.00014267098,0.00010402788,0.000048816666,0.00005231905,0.00005108411,0.00021649346,0.0010277175,0.000009563138],"category_scores_gemma":[0.000087542925,0.00013191359,0.000075390235,0.00017106616,0.00003397588,0.0000017501975,0.00010153999,0.00057382614,0.000020560212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002271582,0.000012900689,0.0002539552,0.000023775527,0.00004933506,0.000013393587,0.00001904411,0.0015062469,0.96155715,0.0009273883,0.032767955,0.0028461227],"study_design_scores_gemma":[0.0007330616,0.00016057999,0.033201016,0.000014868347,0.000037380156,0.00002610621,0.00005247095,0.004203254,0.59065175,0.00045863463,0.36996928,0.00049156597],"about_ca_topic_score_codex":9.1382003e-7,"about_ca_topic_score_gemma":0.000004399615,"teacher_disagreement_score":0.3709054,"about_ca_system_score_codex":0.000005442798,"about_ca_system_score_gemma":0.000025857453,"threshold_uncertainty_score":0.79266983},"labels":[],"label_agreement":null},{"id":"W4382515335","doi":"10.1101/2023.06.28.546861","title":"Comparable analysis of multiple DNA double-strand break repair pathways in CRISPR-mediated endogenous tagging","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Japan Science and Technology Agency; Kato Memorial Bioscience Foundation; Uehara Memorial Foundation; Kanae Foundation for the Promotion of Medical Science; Sumitomo Foundation; University of Tokyo; Institute of Genetics; Naito Foundation","keywords":"CRISPR; DNA repair; Homology directed repair; Amplicon; Computational biology; Biology; Homologous recombination; Cas9; DNA; Gene; Gene knockin; Genome editing; Double strand; Genetics; Nucleotide excision repair; Polymerase chain reaction","score_opus":0.02736865420157008,"score_gpt":0.2549925739369967,"score_spread":0.22762391973542662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382515335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924682,0.001981424,0.0034909965,0.000023252076,0.0004789544,0.0005951415,0.00070422183,0.00024384574,0.000014008472],"genre_scores_gemma":[0.9973673,0.0006526006,0.0014761608,0.00003749073,0.00016342627,0.00014501209,0.000023139983,0.00012973679,0.0000050829995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969672,0.00008658368,0.00084860064,0.0011255648,0.00031696016,0.00065508566],"domain_scores_gemma":[0.99770766,0.00006848809,0.00032471342,0.0014118693,0.0002737765,0.00021346415],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065535685,0.000549713,0.0009462209,0.0007192577,0.00007317929,0.000052983956,0.00050171686,0.0006159876,0.000014357495],"category_scores_gemma":[0.00017930946,0.00064499705,0.00048607838,0.0011899243,0.00008900951,0.0000067981314,0.0004592392,0.00044551765,0.000011139942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100870246,0.00013193848,0.03752473,0.00032931144,0.0011690931,0.00005387306,0.000023351775,0.035475694,0.9250632,0.0000123789005,0.00011503722,5.093711e-7],"study_design_scores_gemma":[0.0014000463,0.00006737317,0.102393724,0.00017200585,0.0006003797,3.5001797e-8,0.000013919522,0.0118668275,0.8814758,2.9727636e-7,0.0012622629,0.0007473134],"about_ca_topic_score_codex":0.00053695415,"about_ca_topic_score_gemma":0.00024006882,"teacher_disagreement_score":0.064868994,"about_ca_system_score_codex":0.000084150975,"about_ca_system_score_gemma":0.00029755957,"threshold_uncertainty_score":0.9996001},"labels":[],"label_agreement":null},{"id":"W4382631547","doi":"10.1186/s13059-023-02990-1","title":"Efficient and versatile multiplex prime editing in hexaploid wheat","year":2023,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Universities Scientific Fund; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Biology; Multiplex; Human genetics; Prime (order theory); Computational biology; Genetics; Evolutionary biology; Gene","score_opus":0.008707241743227494,"score_gpt":0.2949011326719764,"score_spread":0.28619389092874886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382631547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973691,0.0010773742,0.00085870165,0.000086527994,0.00020256377,0.0001208485,0.000016932367,0.000027266024,0.00024065764],"genre_scores_gemma":[0.9989946,0.00013087266,0.00029173784,0.000046571487,0.0002500559,0.000017790973,0.00012689942,0.000013737966,0.00012776577],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99924743,0.000024642784,0.00013226534,0.00028074224,0.000029988889,0.0002849511],"domain_scores_gemma":[0.9997518,0.0000145109725,0.000019456567,0.00015080548,0.000013811626,0.000049616756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015277069,0.0001006067,0.00011001355,0.000082794504,0.0000340787,0.00000588997,0.00007737994,0.000116649746,0.000011873352],"category_scores_gemma":[0.00005397902,0.00010069324,0.000026395704,0.00011060258,0.0000473508,4.6110583e-7,0.00014155707,0.000058417216,0.00002549304],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010706773,0.000008809601,0.0070359395,0.000009964465,0.00000946125,0.000002797046,0.00012005141,0.0031749967,0.9877192,0.0000142885965,0.000054744596,0.0018390376],"study_design_scores_gemma":[0.0038066593,0.0011233017,0.45760265,0.00003720681,0.00002590177,0.000064062806,0.0012085445,0.023162136,0.3843102,0.00012690126,0.12738238,0.0011500722],"about_ca_topic_score_codex":0.000024103054,"about_ca_topic_score_gemma":0.00003117587,"teacher_disagreement_score":0.60340905,"about_ca_system_score_codex":0.000009971221,"about_ca_system_score_gemma":0.000013938152,"threshold_uncertainty_score":0.41061515},"labels":[],"label_agreement":null},{"id":"W4382751588","doi":"10.1021/acs.analchem.2c05032","title":"Strategies to Improve Multi-enzyme Compatibility and Coordination in One-Pot SHERLOCK","year":2023,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada; University of Manitoba; Canadian Food Inspection Agency","funders":"Canadian Institutes of Health Research; Government of Canada; Research Manitoba","keywords":"Recombinase Polymerase Amplification; Chemistry; Computational biology; Polymerase chain reaction; Polymerase; Enzyme; Loop-mediated isothermal amplification; Recombinase; Nucleic acid; Nanotechnology; Combinatorial chemistry; DNA; Biochemical engineering; Biochemistry; Recombination; Gene; Biology; Materials science","score_opus":0.018858858756944177,"score_gpt":0.32507509606392826,"score_spread":0.3062162373069841,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382751588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948106,0.0000677617,0.003712345,0.00030434277,0.000031892854,0.000093300776,0.000010639146,0.000024899735,0.00094426656],"genre_scores_gemma":[0.9982488,0.000012134715,0.0003080445,0.000037951482,0.000100358164,0.000012786652,0.000058096604,0.000010993235,0.0012107993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921095,0.000008542933,0.00016352066,0.00032588924,0.00008307074,0.00020802498],"domain_scores_gemma":[0.9996178,0.00001558757,0.000014348089,0.00020843522,0.00003674648,0.00010704591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013628084,0.00010936364,0.00012553202,0.000024073452,0.000022551785,0.00003069776,0.000085938074,0.00011327796,0.000013439337],"category_scores_gemma":[0.00011033241,0.00011868536,0.00003324543,0.00016916014,0.000038559392,0.0000033196889,0.000101044076,0.000090036076,0.000008354962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019412653,0.000048247453,0.0047105053,0.000088336936,0.00001903841,0.0000033930864,0.000039110204,0.0010298216,0.9926703,0.00002054987,0.0009130476,0.00043826082],"study_design_scores_gemma":[0.0008093657,0.000091216156,0.05834288,0.000025638821,0.000020777188,0.0000033905233,0.00055749447,0.043002184,0.893527,0.00009002353,0.0031713666,0.00035870622],"about_ca_topic_score_codex":0.000028374014,"about_ca_topic_score_gemma":0.000043684635,"teacher_disagreement_score":0.09914332,"about_ca_system_score_codex":0.0000151883305,"about_ca_system_score_gemma":0.000028277853,"threshold_uncertainty_score":0.48398486},"labels":[],"label_agreement":null},{"id":"W4382777420","doi":"10.1038/s42003-023-05052-1","title":"CRISPR prime editing for unconstrained correction of oncogenic KRAS variants","year":2023,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Foundation of Korea; National Research Foundation; Public Health Agency of Canada","keywords":"KRAS; CRISPR; Indel; Mutation; Biology; Genetics; Oncogene; Cancer research; Computational biology; Gene; Cancer; Genotype; Cell cycle","score_opus":0.02785743326563239,"score_gpt":0.38855577533643815,"score_spread":0.36069834207080576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382777420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5849623,0.0040853694,0.3954306,0.0020253693,0.003446057,0.0013818911,0.0003603541,0.00025550206,0.008052561],"genre_scores_gemma":[0.99318045,0.00035691634,0.0050819376,0.000034805595,0.00014030436,0.000079205594,0.0008264711,0.000013968216,0.00028593504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994018,0.00004868349,0.00021187929,0.0001554715,0.000023037817,0.00015914124],"domain_scores_gemma":[0.9989802,0.00008809464,0.00007523977,0.0007229436,0.00010415536,0.000029338375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023964266,0.00007902087,0.00011496259,0.0000688365,0.00009626704,0.000003931159,0.0003494957,0.00012573568,0.0000061182313],"category_scores_gemma":[0.00032073024,0.00008398754,0.00007338213,0.00015984847,0.00011678036,0.0000015615458,0.00020019988,0.000060799004,0.0000072556554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012899414,0.00002784638,0.0010786415,0.000010829858,0.000052974425,5.3190224e-8,0.00005341728,0.00019292074,0.97829574,0.00057900994,0.0019860654,0.017709622],"study_design_scores_gemma":[0.0010850666,0.0005440246,0.005783303,0.000033307067,0.00006793839,0.000018591372,0.000566334,0.01850509,0.8092607,0.0008307251,0.16297987,0.00032504037],"about_ca_topic_score_codex":0.000013396646,"about_ca_topic_score_gemma":0.000035183184,"teacher_disagreement_score":0.40821815,"about_ca_system_score_codex":0.000007845087,"about_ca_system_score_gemma":0.000051749714,"threshold_uncertainty_score":0.34249124},"labels":[],"label_agreement":null},{"id":"W4382934692","doi":"10.20944/preprints202306.2128.v1","title":"Diversity of Transgene Integration and Gene Editing Events in Wheat (T&lt;em&gt;riticum aestivum&lt;/em&gt; L.) Transgenic Plants Generated Using Agrobacterium-Mediated Transformation","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Saskatchewan Wheat Development Commission; Alberta Wheat Commission; Western Grains Research Foundation","keywords":"Biology; Transgene; Transformation (genetics); Population; Genome editing; Gene; Genetics; Epigenetics; CRISPR; Genetically modified crops; Genetic diversity; Cas9","score_opus":0.05228334656254856,"score_gpt":0.30727759074606686,"score_spread":0.2549942441835183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382934692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9753936,0.00041174106,0.02231369,0.00004924677,0.00062102993,0.00079299643,0.0003281823,0.00006351121,0.00002600632],"genre_scores_gemma":[0.9959824,0.0014663967,0.0004702122,0.000017485432,0.00017731187,0.00004816191,0.0017425886,0.00006395268,0.000031507054],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99728394,0.00017108959,0.0008359615,0.00088911614,0.00035715208,0.00046275125],"domain_scores_gemma":[0.9989218,0.000025047984,0.0002191626,0.0005074956,0.00017116904,0.00015528497],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067114475,0.00049186713,0.0005565205,0.00028712896,0.00016860402,0.000012101805,0.0003583083,0.0006675786,0.000027419781],"category_scores_gemma":[0.000097515265,0.0005724641,0.00020357437,0.00020402182,0.00006138453,0.000024405543,0.0006114501,0.00043482328,0.000009522033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014335601,0.000084928615,0.027382005,0.00035485608,0.0001517086,0.000005585355,0.0029393965,0.019408744,0.9490406,0.0000016338871,0.0000026476343,0.00048455127],"study_design_scores_gemma":[0.0010818946,0.000049052764,0.27247825,0.0003401558,0.00010842751,0.000014335843,0.0002118922,0.007153165,0.71804655,0.000037154943,0.000030775307,0.00044833883],"about_ca_topic_score_codex":0.00018206915,"about_ca_topic_score_gemma":0.00084690726,"teacher_disagreement_score":0.24509627,"about_ca_system_score_codex":0.00009095575,"about_ca_system_score_gemma":0.00011726162,"threshold_uncertainty_score":0.99967265},"labels":[],"label_agreement":null},{"id":"W4382936900","doi":"10.1111/pbi.14114","title":"Creation of herbicide‐resistance in allotetraploid peanut using <scp>CRISPR</scp>/Cas9‐meditated cytosine base‐editing","year":2023,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Henan Provincial Science and Technology Research Project; National Key Research and Development Program of China; Natural Science Foundation of Henan Province","keywords":"Biology; Genome editing; CRISPR; Arachis hypogaea; Genetics; Point mutation; Gene; Cas9; Acetolactate synthase; Genome; Computational biology; Guide RNA; Mutation; Biotechnology; Botany","score_opus":0.012256477775202437,"score_gpt":0.27514017260292695,"score_spread":0.2628836948277245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382936900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9820342,0.0026936198,0.014317126,0.0002835089,0.00033162054,0.000102545484,0.000051643812,0.000060203718,0.00012549582],"genre_scores_gemma":[0.99405515,0.0016355775,0.00374665,0.000030154806,0.00026362127,0.0000036146375,0.00012256675,0.00002939321,0.00011328059],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986241,0.00004660625,0.00045595606,0.00027046603,0.00017053697,0.00043232908],"domain_scores_gemma":[0.9993961,0.00005573215,0.00019519622,0.0002126001,0.00007081959,0.00006957307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045517727,0.00018480519,0.00024414485,0.00045466455,0.00009004748,0.000017787905,0.00024147585,0.00034437803,0.0000052563596],"category_scores_gemma":[0.0005302234,0.00018830963,0.00007794432,0.0005015133,0.0001024386,0.000007918425,0.00008711789,0.0004093968,0.0000039773486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017955386,0.000029639024,0.0048959567,0.00004080889,0.000048696536,0.00011769658,0.00007578755,0.0029155929,0.9902959,0.000038737922,0.0010628308,0.0004604265],"study_design_scores_gemma":[0.0007118793,0.000113497685,0.007135819,0.00017927018,0.000025677655,0.000467455,0.0005928608,0.0035291535,0.9812163,0.00013472156,0.005783825,0.000109501576],"about_ca_topic_score_codex":0.000020225614,"about_ca_topic_score_gemma":0.00014179441,"teacher_disagreement_score":0.0120209055,"about_ca_system_score_codex":0.000032900414,"about_ca_system_score_gemma":0.000061085244,"threshold_uncertainty_score":0.7679044},"labels":[],"label_agreement":null},{"id":"W4383196636","doi":"10.21203/rs.3.rs-3067668/v1","title":"Generation of a C57Bl/6J mouse strain expressing the CD45.1 epitope to improve HSC engraftment and adoptive cell transfer experiments","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Université de Lyon; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale","keywords":"Epitope; Adoptive cell transfer; Strain (injury); Cell biology; Biology; Chemistry; Molecular biology; Virology; T cell; Immunology; Antibody; Immune system","score_opus":0.08473207355619318,"score_gpt":0.41676897596379314,"score_spread":0.3320369024076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383196636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9793405,0.0027344276,0.015721682,0.00017953919,0.0001656748,0.0013773671,0.00038102648,0.000015404807,0.00008440087],"genre_scores_gemma":[0.9963553,0.00090100133,0.00090829405,0.000018442133,0.00035494124,0.000421724,0.00029617478,0.000053478332,0.00069067086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981555,0.00018560792,0.00025652378,0.00058947416,0.00042771103,0.00038523736],"domain_scores_gemma":[0.9990097,0.00003340023,0.000027360551,0.00058713724,0.00020546967,0.00013690123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006327255,0.00021994872,0.00019789263,0.00011570845,0.0001238981,0.00008650903,0.00027721043,0.00023679464,0.000010520646],"category_scores_gemma":[0.00006500612,0.00018148906,0.00009869868,0.0000944211,0.00008371257,0.0000026839155,0.000647676,0.00037604282,0.0000035577052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000430628,0.000053510157,0.000028046677,0.00023485062,0.000050769635,0.0000027897208,0.0015895874,0.004152812,0.99049133,0.000011359834,0.00049583096,0.0028460547],"study_design_scores_gemma":[0.00031242118,0.00037822468,0.00030366122,0.00008768124,0.000011369168,5.763644e-7,0.0012964169,0.0011305301,0.99508667,0.00001671937,0.0011910207,0.0001847014],"about_ca_topic_score_codex":0.00010411189,"about_ca_topic_score_gemma":0.000039788734,"teacher_disagreement_score":0.017014796,"about_ca_system_score_codex":0.000039264138,"about_ca_system_score_gemma":0.00012325551,"threshold_uncertainty_score":0.74009085},"labels":[],"label_agreement":null},{"id":"W4383226457","doi":"10.1136/jme-2023-109061","title":"Guerrilla eugenics: gene drives in heritable human genome editing","year":2023,"lang":"en","type":"article","venue":"Journal of Medical Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Genome editing; Eugenics; CRISPR; Genome; Bioethics; Genetics; Biology; Human genome; Human genetics; Cas9; Gene","score_opus":0.024889606380148005,"score_gpt":0.38250375514905777,"score_spread":0.35761414876890973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383226457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98668796,0.0026470681,0.005550901,0.003954583,0.00071747706,0.000048879814,0.0000036684432,0.000011549081,0.0003778932],"genre_scores_gemma":[0.99302363,0.0034954643,0.000842136,0.00040454254,0.0020399978,0.000001552992,0.000016769307,0.000019116336,0.0001567934],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982251,0.00007596068,0.0004248951,0.00012608278,0.00089860434,0.00024938243],"domain_scores_gemma":[0.99935997,0.000071910035,0.00010459176,0.00013136954,0.00014638722,0.00018575035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031767946,0.00009558778,0.0001797442,0.00010143973,0.00005813265,0.000016962738,0.00030197605,0.00056865235,0.00004517684],"category_scores_gemma":[0.0018697159,0.00008704601,0.000095907155,0.00016454198,0.000071361355,0.0000032949035,0.00013595703,0.0011022658,0.0000059969498],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020013951,0.00005847833,0.0017312537,0.00013851367,0.0000916615,0.0003362385,0.001149386,0.0055172485,0.986617,0.0002924188,0.0022565476,0.0017911978],"study_design_scores_gemma":[0.007669747,0.0022076126,0.06251665,0.0013251404,0.0001312826,0.0016860369,0.006129731,0.004593271,0.31763595,0.0036335385,0.59095055,0.0015204746],"about_ca_topic_score_codex":0.000013948394,"about_ca_topic_score_gemma":0.0000942513,"teacher_disagreement_score":0.6689811,"about_ca_system_score_codex":0.00001521182,"about_ca_system_score_gemma":0.0003012443,"threshold_uncertainty_score":0.47888577},"labels":[],"label_agreement":null},{"id":"W4383315117","doi":"10.1101/2023.07.05.547852","title":"pUdOs: concise plasmids for bacterial and mammalian cells","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Government of Ontario; University of Ottawa","keywords":"Plasmid; Biology; Escherichia coli; Promoter; Expression vector; Genetics; Vector (molecular biology); Cloning vector; Multiple cloning site; Transcription (linguistics); Computational biology; Gene; Gene expression; Recombinant DNA","score_opus":0.011939139439608762,"score_gpt":0.2479462321851803,"score_spread":0.23600709274557155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383315117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98456925,0.00093995634,0.009658406,0.000107549284,0.002757709,0.00084755925,0.0009680314,0.0001488636,0.0000026479825],"genre_scores_gemma":[0.99204165,0.0005272715,0.005364357,0.0000733466,0.0014370143,0.00031158162,0.000005388841,0.00019038221,0.00004903328],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980746,0.00003320328,0.00035031437,0.0009207969,0.00014063864,0.0004804478],"domain_scores_gemma":[0.9986535,0.00002704828,0.00013456639,0.0007742029,0.00017854988,0.00023214164],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030416562,0.0004494098,0.0003716907,0.00010396551,0.000093268136,0.00014260646,0.00031444145,0.00062566076,0.000012193704],"category_scores_gemma":[0.00011887098,0.0005195942,0.00014795535,0.00009194731,0.00008625802,0.0000041234075,0.00050725427,0.00022701031,0.000016040067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060927337,0.000021915685,0.0002978372,0.0004009609,0.00010207747,0.000007797542,0.0000032335397,0.00017343934,0.9966975,0.000034476798,0.0021963785,0.0000034904556],"study_design_scores_gemma":[0.00069570437,0.000114584705,0.0055522043,0.000092333736,0.000081007194,1.9077534e-8,0.0000023496013,0.0002646734,0.94700694,0.0000013966941,0.04557423,0.0006145492],"about_ca_topic_score_codex":0.000017983033,"about_ca_topic_score_gemma":0.0000056145627,"teacher_disagreement_score":0.049690515,"about_ca_system_score_codex":0.000033315177,"about_ca_system_score_gemma":0.00020703228,"threshold_uncertainty_score":0.9997256},"labels":[],"label_agreement":null},{"id":"W4384008721","doi":"10.1002/adma.202300665","title":"Engineered Nanomaterials to Potentiate CRISPR/Cas9 Gene Editing for Cancer Therapy","year":2023,"lang":"en","type":"review","venue":"Advanced Materials","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Guangdong Provincial Pearl River Talents Program; National Key Research and Development Program of China; Youth Innovation Promotion Association of the Chinese Academy of Sciences; China Primary Health Care Foundation; National Natural Science Foundation of China","keywords":"CRISPR; Genome editing; Cas9; Genetic enhancement; Computational biology; Nanomedicine; Viral vector; Biology; Gene; Nanotechnology; Computer science; Materials science; Genetics","score_opus":0.0374894983717245,"score_gpt":0.4035128304552069,"score_spread":0.3660233320834824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384008721","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002185075,0.9812072,0.005994141,0.00001795164,0.0055452604,0.00237212,0.0025404785,0.0001254708,0.000012289016],"genre_scores_gemma":[0.00020941727,0.9867386,0.004323153,0.00006651475,0.0031941356,0.0030267164,0.0013667378,0.00030918387,0.000765541],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976078,0.00005948493,0.0007890263,0.00076260004,0.00016069895,0.0006203793],"domain_scores_gemma":[0.99886084,0.00003720362,0.00025832848,0.0005588972,0.0001463281,0.00013838023],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040435852,0.0006098186,0.0013719895,0.0001294214,0.0000880962,0.000093556715,0.00038159877,0.00036866535,0.000057358102],"category_scores_gemma":[0.00020585267,0.00055449666,0.000312859,0.00014451126,0.000015993162,0.0000052805863,0.00017397606,0.000050188726,0.000046132347],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003711821,0.000010660708,2.6133419e-8,0.0039645024,0.00023616674,0.00000444612,0.000011810564,0.0003094044,0.83927035,0.0000069124144,0.00094367086,0.1552049],"study_design_scores_gemma":[0.00022580402,0.000078617355,3.0892522e-7,0.00089719077,0.000089693815,0.000010034159,0.0000032305768,3.472292e-7,0.45319414,0.000009009106,0.5451382,0.0003534477],"about_ca_topic_score_codex":0.000010598823,"about_ca_topic_score_gemma":0.000004747636,"teacher_disagreement_score":0.5441945,"about_ca_system_score_codex":0.00004656498,"about_ca_system_score_gemma":0.000118011034,"threshold_uncertainty_score":0.99969065},"labels":[],"label_agreement":null},{"id":"W4384103458","doi":"10.1016/j.talanta.2023.124931","title":"Development of an inducible Cas9 nickase and PAM-free Cas12a platform for bacterial diagnostics","year":2023,"lang":"en","type":"article","venue":"Talanta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Government of New Brunswick; Agriculture and Agri-Food Canada","funders":"","keywords":"Cas9; CRISPR; Trans-activating crRNA; Computational biology; DNA; Chemistry; Genome editing; Polymerase; Molecular biology; Biology; Biochemistry; Gene","score_opus":0.019829262178448444,"score_gpt":0.2998362579017281,"score_spread":0.28000699572327964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384103458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991072,0.00010018806,0.000303416,0.000011823591,0.00014906104,0.00013343668,0.0001141063,0.00001234736,0.00006841981],"genre_scores_gemma":[0.9962173,0.00015177585,0.002671069,0.00001286748,0.00016737457,0.000026040583,0.0006121337,0.000017989256,0.0001234477],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949944,0.0000028923648,0.00013546151,0.0001601771,0.000050606177,0.0001513968],"domain_scores_gemma":[0.99966216,0.000017158392,0.000025691383,0.00021479648,0.000021372358,0.00005883764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010056953,0.00008159256,0.00008969677,0.0000311775,0.000038302973,0.000008935337,0.00009398348,0.00007427825,0.000005861516],"category_scores_gemma":[0.000081826394,0.000080595724,0.00001943089,0.00004249845,0.000018016075,0.0000022876886,0.00011480537,0.000023862323,0.0000016839623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006474766,0.000028098157,0.00042700185,0.000081619146,0.000033674634,0.0000048718903,0.00041041846,0.000046483263,0.9878414,0.000028908174,0.001974527,0.009058197],"study_design_scores_gemma":[0.000793061,0.00016473097,0.0050176983,0.000013446433,0.000013949712,0.000016133494,0.0001822824,0.00018119912,0.9635817,0.000037780315,0.02984855,0.00014948947],"about_ca_topic_score_codex":0.00000845633,"about_ca_topic_score_gemma":0.00015680132,"teacher_disagreement_score":0.02787402,"about_ca_system_score_codex":0.0000038270573,"about_ca_system_score_gemma":0.000043148364,"threshold_uncertainty_score":0.32865983},"labels":[],"label_agreement":null},{"id":"W4384120674","doi":"10.1089/crispr.2023.0019","title":"CRISPR-Cas-Based Biomonitoring for Marine Environments: Toward CRISPR RNA Design Optimization Via Deep Learning","year":2023,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina","funders":"National Heart, Lung, and Blood Institute; Universidad de La Frontera; Agencia Nacional de Investigación y Desarrollo; Ministry of Business, Innovation and Employment; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Biomonitoring; Computer science; Computational biology; Biochemical engineering; Environmental science; Biology; Ecology; Engineering; Genetics","score_opus":0.019620439292245554,"score_gpt":0.31208871927278264,"score_spread":0.2924682799805371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384120674","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015320565,0.0006799814,0.982334,0.0005705854,0.0006831956,0.00030593347,0.0000033961553,0.000045635574,0.000056667483],"genre_scores_gemma":[0.97418904,0.0013573765,0.022154203,0.00015770835,0.0013904432,0.000069875685,0.00008502847,0.00010245741,0.0004938847],"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984357,0.00013513117,0.0003618153,0.00030050628,0.0002466647,0.0005202147],"domain_scores_gemma":[0.9992585,0.00008134556,0.00014876899,0.0002892065,0.000071174174,0.00015096983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00087936636,0.0002569153,0.00018722887,0.00012478593,0.0004744741,0.00011317463,0.00035291663,0.00014460193,0.00006669233],"category_scores_gemma":[0.00019833609,0.00021333767,0.0001848544,0.0001862958,0.000053986285,0.000011800227,0.00014049136,0.000305527,0.000021753773],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012684515,0.000027630627,0.00029488906,0.000021756689,0.000080790844,0.000008530301,0.00014244045,0.74507666,0.24232455,0.000002639688,0.0008611878,0.011032063],"study_design_scores_gemma":[0.0013504132,0.0004863936,0.001009761,0.000026042493,0.000115725416,0.00007917185,0.00042293023,0.2978141,0.6865962,0.00012116973,0.011592095,0.00038601505],"about_ca_topic_score_codex":0.0000069425114,"about_ca_topic_score_gemma":0.0000013237545,"teacher_disagreement_score":0.96017987,"about_ca_system_score_codex":0.0000533295,"about_ca_system_score_gemma":0.000039224484,"threshold_uncertainty_score":0.8699658},"labels":[],"label_agreement":null},{"id":"W4384563026","doi":"10.1016/j.omtm.2023.07.004","title":"Prevention of early-onset cardiomyopathy in Dmd exon 52–54 deletion mice by CRISPR-Cas9-mediated exon skipping","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; Hospital for Sick Children; McMaster University; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"CRISPR; Exon; Exon skipping; Cardiomyopathy; Cas9; Genetics; Genome editing; Biology; Medicine; Internal medicine; Gene; Heart failure; Alternative splicing","score_opus":0.04409454052440444,"score_gpt":0.44370115385608483,"score_spread":0.3996066133316804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384563026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7093626,0.0018221156,0.28802848,0.0000594282,0.00027784234,0.00036703213,0.0000071073755,0.000033844455,0.00004152066],"genre_scores_gemma":[0.89033395,0.0027524098,0.10576743,0.000226861,0.00007052128,0.0001385314,0.0004486988,0.00006835123,0.00019325882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996566,0.00095777033,0.0010874417,0.0006594152,0.00028747442,0.00044190054],"domain_scores_gemma":[0.99899215,0.00015760856,0.00020029525,0.00040144162,0.000112097085,0.00013642559],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0035857714,0.00029467288,0.00048796085,0.00016828017,0.000051494568,0.000020121046,0.0002723454,0.0003735467,0.000013977656],"category_scores_gemma":[0.00045094508,0.00030810328,0.00025884245,0.0004896171,0.00006296956,0.000006184446,0.00014825279,0.00024735922,0.000017112365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019093593,0.00014222969,0.005843617,0.000038429796,0.00017187702,0.000013945126,0.00021553389,0.0002392161,0.81903607,0.000002415445,0.00024519366,0.17386054],"study_design_scores_gemma":[0.0016521127,0.00045597422,0.07691002,0.000083489154,0.00002129728,0.0000051266857,0.00007012629,0.00023803674,0.8947171,0.00010636631,0.025312472,0.00042785512],"about_ca_topic_score_codex":0.000028660968,"about_ca_topic_score_gemma":0.0000100095185,"teacher_disagreement_score":0.18226105,"about_ca_system_score_codex":0.000036442252,"about_ca_system_score_gemma":0.00014867239,"threshold_uncertainty_score":0.9999371},"labels":[],"label_agreement":null},{"id":"W4384916116","doi":"10.2139/ssrn.4499951","title":"Strong Expression of Cas9 Under a New 3’-Truncated TEF1α Promoter Enhances CRISPR-Cas9-Mediated Genome Editing in &lt;i&gt;Yarrowia Lipolytica&lt;/i&gt;","year":2023,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Yarrowia; CRISPR; Genome editing; Cas9; CRISPR interference; Biology; Genetics; Genome; Yeast; Computational biology; Gene","score_opus":0.01102005312549932,"score_gpt":0.2817813172903609,"score_spread":0.27076126416486157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384916116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9149109,0.021396726,0.06138054,0.00042865015,0.0010083335,0.0005837765,0.000050390954,0.000063026964,0.00017761612],"genre_scores_gemma":[0.9876301,0.008081958,0.00047060775,0.000023441044,0.0016803846,0.00003299234,0.00031698044,0.00014498245,0.0016185144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99513245,0.00014844387,0.0010102101,0.0008217603,0.00049222034,0.002394926],"domain_scores_gemma":[0.9984046,0.000044667813,0.00053002115,0.00059497904,0.00017848106,0.00024720983],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0012412043,0.000597803,0.0006518586,0.00036881646,0.00010720004,0.00007710948,0.00072267524,0.0007361197,0.00004064499],"category_scores_gemma":[0.00023710384,0.0005856156,0.000329211,0.00027088184,0.00008414586,0.000013976022,0.0005964009,0.0023776789,0.000014963043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009264383,0.000075835895,0.0001683352,0.00009911624,0.00026473816,0.000013657588,0.0002119437,0.007375775,0.9903754,0.00016138934,0.00025681825,0.00090431987],"study_design_scores_gemma":[0.0044327746,0.001659229,0.006318312,0.0015949993,0.00040656925,0.0005120588,0.0014284138,0.0024817486,0.9576354,0.014300038,0.0067264093,0.002504066],"about_ca_topic_score_codex":0.000071753435,"about_ca_topic_score_gemma":0.0017951591,"teacher_disagreement_score":0.0727192,"about_ca_system_score_codex":0.00042833597,"about_ca_system_score_gemma":0.0029848525,"threshold_uncertainty_score":0.9999239},"labels":[],"label_agreement":null},{"id":"W4384925674","doi":"10.1038/s41594-023-01045-0","title":"The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure","year":2023,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Texas MD Anderson Cancer Center; H. Lundbeck A/S; Novo Nordisk Fonden; University of Dundee; Nordea-fonden; Danmarks Tekniske Universitet; Danish e-Infrastructure Cooperation; U.S. Bureau of Land Management; Novo Nordisk; National Research Foundation; University of Toronto; Lundbeckfonden; Danmarks Grundforskningsfond; University of Oxford; Johns Hopkins University","keywords":"Mitosis; Cell biology; DNA; Chemistry; Biophysics; Computational biology; Biology; Biochemistry","score_opus":0.0031162260058327173,"score_gpt":0.30584428581801676,"score_spread":0.30272805981218404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384925674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893533,0.005351888,0.00086954917,0.002951417,0.00079113914,0.0004717732,0.00005126616,0.00008398023,0.00007567291],"genre_scores_gemma":[0.99766797,0.00013753196,0.00037544494,0.0005675929,0.0003391504,0.000067474975,0.0003224726,0.00004375736,0.00047857952],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832225,0.000081340826,0.0002442976,0.00058236974,0.0001474749,0.00062226795],"domain_scores_gemma":[0.9990947,0.000031668616,0.00005994853,0.000513198,0.00015684552,0.00014363014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014246073,0.00031442122,0.00020726862,0.00007966499,0.00020825923,0.000046780675,0.0005313508,0.0005151002,0.0000077705645],"category_scores_gemma":[0.0004511871,0.00021114183,0.0001290956,0.00046573518,0.00009384862,0.000002901459,0.00026977854,0.0003199567,0.000024624433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028560966,0.0000051104994,0.00013327794,0.000040880874,0.00007649674,0.000016149046,0.00004904814,0.0005169418,0.9937988,0.00047563112,0.0022282798,0.0026308259],"study_design_scores_gemma":[0.00019056989,0.0002464012,0.0015417127,0.000014378713,0.000018881317,0.00006504749,0.00008573394,0.000036720237,0.9163682,0.0008107449,0.080285914,0.000335684],"about_ca_topic_score_codex":0.0000075565767,"about_ca_topic_score_gemma":0.00014320458,"teacher_disagreement_score":0.07805764,"about_ca_system_score_codex":0.000016587848,"about_ca_system_score_gemma":0.000102958606,"threshold_uncertainty_score":0.8610114},"labels":[],"label_agreement":null},{"id":"W4384938247","doi":"10.1016/j.molcel.2023.06.025","title":"Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens","year":2023,"lang":"en","type":"article","venue":"Molecular Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Human Genome Research Institute; Canadian Cancer Society","keywords":"Biology; DNA damage; Gene; DNA repair; Genetics; CRISPR; Phenotype; Genome; DNA replication; DNA","score_opus":0.010071863029891534,"score_gpt":0.2614268006744917,"score_spread":0.25135493764460015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384938247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9124742,0.001041393,0.07783018,0.00007927002,0.00012645098,0.0001956506,0.000037955648,0.000048425034,0.008166489],"genre_scores_gemma":[0.99446416,0.00015897998,0.0038310415,0.000105079926,0.00008993879,0.000015659754,0.0002485251,0.000058824033,0.0010278095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987324,0.000040230345,0.00025836725,0.00039494951,0.00018046914,0.00039360477],"domain_scores_gemma":[0.9992077,0.0000085979,0.00006252612,0.0005832078,0.000058401627,0.00007958226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012973431,0.00020572185,0.0002023796,0.00007864529,0.000053947653,0.000015872372,0.00028338702,0.00014895666,0.000045638142],"category_scores_gemma":[0.000022636756,0.00022731803,0.00016501099,0.00028688333,0.000062062834,0.0000035430178,0.00023142806,0.00010029164,0.000053782387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011651936,0.000030875002,0.00024712525,0.000093404684,0.000036340814,0.000022009923,0.00024186625,0.0051878206,0.99339086,0.00002536037,0.0005624503,0.00015022946],"study_design_scores_gemma":[0.00040518556,0.000085134736,0.0036983332,0.000013011191,0.000025802701,0.000002769896,0.00025640702,0.00038650073,0.9672086,0.00008300919,0.027580356,0.00025487866],"about_ca_topic_score_codex":0.000020159438,"about_ca_topic_score_gemma":0.0000076214383,"teacher_disagreement_score":0.08198995,"about_ca_system_score_codex":0.000007780352,"about_ca_system_score_gemma":0.000033136243,"threshold_uncertainty_score":0.926976},"labels":[],"label_agreement":null},{"id":"W4384939889","doi":"10.1093/oso/9780198874522.003.0007","title":"Genetic welding","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Genome editing; Cas9; CRISPR; Genome; Gene; Gene drive; Genetics; Caenorhabditis elegans; Synthetic biology; Computational biology; Evolutionary biology","score_opus":0.011566569696107991,"score_gpt":0.27048398277573177,"score_spread":0.2589174130796238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384939889","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004892837,0.0015275988,0.009183914,0.00004653494,0.0006038448,0.00016462669,0.00002039318,0.0000959554,0.98786783],"genre_scores_gemma":[0.007454635,0.0012857493,0.0010884186,0.00008959326,0.0007407996,0.0000069254966,0.00008556245,0.00012336027,0.98912495],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99919486,0.0000021655683,0.00016711741,0.00034502923,0.00010725876,0.00018356835],"domain_scores_gemma":[0.999495,0.0000056087956,0.000033857275,0.00036619854,0.000029899424,0.000069393674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000042278763,0.00022285094,0.00014712235,0.000058495636,0.000030179142,0.000015543956,0.00014900386,0.00032189122,0.0002491082],"category_scores_gemma":[0.00001148821,0.00022898677,0.00013429107,0.000011245797,0.000024287992,2.7998888e-7,0.00013991912,0.000109176435,0.00039142033],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088858105,0.000041661595,0.00030621627,0.0006853313,0.0018168921,0.0003162182,0.00010009656,0.010631308,0.35799083,0.07384747,0.44892055,0.10525457],"study_design_scores_gemma":[0.00015846913,0.0001033499,0.00016321724,0.00004760912,0.000045843422,0.000024830631,0.0000052749638,0.000055541524,0.01678651,0.0014951354,0.9805741,0.0005401282],"about_ca_topic_score_codex":0.0000030431472,"about_ca_topic_score_gemma":0.000022164853,"teacher_disagreement_score":0.5316535,"about_ca_system_score_codex":0.000006631198,"about_ca_system_score_gemma":0.000027640555,"threshold_uncertainty_score":0.93378097},"labels":[],"label_agreement":null},{"id":"W4384939927","doi":"10.1093/oso/9780198874522.003.0006","title":"Hijacking genetics","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Genome editing; Cas9; Biology; Genome; Genetics; Computational biology; Caenorhabditis elegans; DNA; Cloning (programming); Gene; Computer science; Programming language","score_opus":0.016523839722928427,"score_gpt":0.2875252266678123,"score_spread":0.27100138694488385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384939927","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023494413,0.0023753701,0.007874762,0.000048308444,0.00064695405,0.00016471985,0.000030186355,0.00009522307,0.9885295],"genre_scores_gemma":[0.0042740824,0.002314832,0.000839534,0.000113725786,0.0007717527,0.0000051357424,0.00023530656,0.00014366816,0.99130195],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991488,0.0000023182774,0.00017877958,0.00035123984,0.00012503356,0.00019381562],"domain_scores_gemma":[0.9994213,0.0000059331896,0.000040526254,0.00041751435,0.00004422933,0.00007048355],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005667325,0.00024021498,0.00015662011,0.00005599037,0.000030395411,0.00001780992,0.00016729978,0.00037211023,0.00016508567],"category_scores_gemma":[0.000010555486,0.00025058739,0.00013826667,0.000011873657,0.000029484563,2.841952e-7,0.0001760285,0.0001236563,0.00030792895],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007243131,0.000040720282,0.0002204009,0.00055219745,0.0016536132,0.00017509963,0.000111010595,0.006078062,0.38616064,0.105208315,0.34982434,0.14990318],"study_design_scores_gemma":[0.00012973725,0.00008479743,0.000038799597,0.000036844027,0.00003842912,0.000012628835,0.000004636889,0.00007627329,0.02632506,0.0012786322,0.97152793,0.00044623646],"about_ca_topic_score_codex":0.0000015636316,"about_ca_topic_score_gemma":0.000024697913,"teacher_disagreement_score":0.62170357,"about_ca_system_score_codex":0.00000756316,"about_ca_system_score_gemma":0.000034517718,"threshold_uncertainty_score":0.99999464},"labels":[],"label_agreement":null},{"id":"W4385170850","doi":"10.1128/mbio.00668-23","title":"Non-homologous end-joining-deficient filamentous fungal strains mitigate the impact of off-target mutations during the application of CRISPR/Cas9","year":2023,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Infrastructure and Water Management; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Concordia University","keywords":"CRISPR; Genome editing; Cas9; Biology; Genetics; Genome; Computational biology; Gene; Guide RNA; Context (archaeology); Genome engineering","score_opus":0.006521299584580972,"score_gpt":0.3025061241764913,"score_spread":0.29598482459191033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385170850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99579704,0.00030908888,0.0029469978,0.00007056809,0.00004686089,0.00023839003,0.00012195051,0.000014012857,0.00045509683],"genre_scores_gemma":[0.9993434,0.000043634347,0.0000737352,0.000010684133,0.000058772068,0.000040994997,0.00010737895,0.000015158163,0.0003062428],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993036,0.000020662601,0.0002033085,0.000166771,0.00010833489,0.0001973159],"domain_scores_gemma":[0.99945587,0.000019013316,0.00008863935,0.00035087432,0.00005463225,0.00003099984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017024163,0.00010576911,0.00010535917,0.00003855692,0.00009029167,0.000009530881,0.00018929613,0.00005986158,0.000024965875],"category_scores_gemma":[0.000030391473,0.00006995158,0.00013475878,0.00017810105,0.00009332677,0.0000016214743,0.00007983732,0.00007101889,0.000008746869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015310154,0.00003518932,0.0020756351,0.000026316946,0.00007484593,0.000001635822,0.0004626563,0.0388587,0.9562778,0.000017807764,0.0003444137,0.0018097183],"study_design_scores_gemma":[0.00032404126,0.0002601295,0.23037302,0.000009979759,0.000026994705,0.000022019887,0.0005030337,0.0076210448,0.75999033,0.000041131716,0.0007047379,0.00012353955],"about_ca_topic_score_codex":0.00008480161,"about_ca_topic_score_gemma":0.000018575687,"teacher_disagreement_score":0.2282974,"about_ca_system_score_codex":0.00001270669,"about_ca_system_score_gemma":0.000043589887,"threshold_uncertainty_score":0.28525427},"labels":[],"label_agreement":null},{"id":"W4385173013","doi":"10.1101/2023.07.21.550110","title":"Sequencing 4.3 million mutations in wheat promoters to understand and modify gene expression","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Food and Agriculture; International Atomic Energy Agency; U.S. Department of Agriculture; Howard Hughes Medical Institute","keywords":"Genetics; Biology; RefSeq; Gene; Promoter; Functional genomics; Coding region; Genomics; Computational biology; Mutation; Gene prediction; Mutant; Genome; Gene expression","score_opus":0.020753414930974594,"score_gpt":0.26487028709703436,"score_spread":0.24411687216605976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385173013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9605732,0.0008414168,0.037288558,0.00015722167,0.00038353514,0.00057797745,0.000094013376,0.00008192288,0.0000021361247],"genre_scores_gemma":[0.988729,0.0003837258,0.010430139,0.000059468464,0.00018514831,0.00010131095,0.000002697386,0.00009993953,0.000008599004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826515,0.000049932063,0.00031061488,0.00083261286,0.00016715046,0.00037454034],"domain_scores_gemma":[0.9990009,0.0000133260955,0.0000742932,0.000611117,0.0000957235,0.00020464713],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027081193,0.00033285885,0.00025997806,0.00025963856,0.00007760323,0.00008560411,0.00019739302,0.00039252845,0.0000022841543],"category_scores_gemma":[0.000107482054,0.0003803529,0.000059010596,0.00023950785,0.000041692554,0.000005990007,0.00043256505,0.00026939847,0.000006638085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015708918,0.000015207333,0.001120735,0.00016189375,0.00002607916,0.000020711117,0.000042085074,0.009247457,0.98924613,0.000006954881,0.000095193835,0.0000018406157],"study_design_scores_gemma":[0.00032174776,0.000060561306,0.014315487,0.0003351354,0.000023582732,4.3118e-8,0.000031222266,0.00094710465,0.98330885,0.0000034829684,0.00018793618,0.00046484775],"about_ca_topic_score_codex":0.000049349837,"about_ca_topic_score_gemma":0.000022237497,"teacher_disagreement_score":0.028155753,"about_ca_system_score_codex":0.00014339869,"about_ca_system_score_gemma":0.00021103672,"threshold_uncertainty_score":0.9998648},"labels":[],"label_agreement":null},{"id":"W4385304500","doi":"10.1038/s41598-023-39166-7","title":"Noncanonical functions of Ku may underlie essentiality in human cells","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ku70; DNA repair; Telomere; Biology; Ku80; Cell biology; DNA damage; Ribosome biogenesis; Genome instability; Mitosis; Cell division; Genetics; Cell cycle; CRISPR; Biogenesis; DNA; Cell; RNA; Gene; Ribosome; DNA-binding protein","score_opus":0.014837926992354625,"score_gpt":0.32050312629887673,"score_spread":0.3056651993065221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385304500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99465764,0.00006504707,0.0010429021,0.00003451853,0.0027688004,0.00009992352,0.0000031221293,0.000017240138,0.001310783],"genre_scores_gemma":[0.99364847,0.000005019504,0.00007132762,0.0000041653634,0.00005580015,0.00000811011,0.00013865995,0.000008969112,0.006059497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989386,0.000019046167,0.00030437834,0.00038873684,0.00015969062,0.00018955217],"domain_scores_gemma":[0.99931455,0.0000052544897,0.00006640765,0.00051657535,0.000046291734,0.000050910818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061726145,0.00007195562,0.000098471886,0.00009689752,0.00007022558,0.00002638361,0.00007598883,0.00006992215,0.000042738615],"category_scores_gemma":[0.000034538265,0.000074251875,0.00007165429,0.00035059103,0.00011608182,0.0000020541456,0.00008986653,0.00005073581,0.000009802873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000021113196,0.00003236544,0.0034879649,0.000019070552,0.00000762008,0.000028654897,0.000025239717,0.0028886255,0.98202395,0.000020963744,0.011287527,0.00017588293],"study_design_scores_gemma":[0.0001305175,0.000027815684,0.008914433,0.000011243129,0.0000076073634,0.000015621461,0.00006923919,0.000086382744,0.9528065,0.0003403753,0.037483808,0.000106458334],"about_ca_topic_score_codex":0.000032708656,"about_ca_topic_score_gemma":0.00013294404,"teacher_disagreement_score":0.029217476,"about_ca_system_score_codex":0.000008505879,"about_ca_system_score_gemma":0.000078197176,"threshold_uncertainty_score":0.30279034},"labels":[],"label_agreement":null},{"id":"W4385384941","doi":"10.1177/26330040231188979","title":"The IRDiRC Chrysalis Task Force: making rare disease research attractive to companies","year":2023,"lang":"en","type":"article","venue":"Therapeutic Advances in Rare Disease","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Neurological Disorders and Stroke; Institut National de la Santé et de la Recherche Médicale; European Commission; Australian Government","keywords":"Task force; Task (project management); Investment (military); Disease; Public relations; Grant funding; Business; Psychology; Medicine; Political science; Marketing; Management; Economics; Pathology; Public administration","score_opus":0.03184840383005678,"score_gpt":0.4197062266891086,"score_spread":0.38785782285905185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385384941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8551292,0.1251436,0.011082393,0.0034932466,0.0010184617,0.0021309897,0.00045247673,0.00024527885,0.00130434],"genre_scores_gemma":[0.9954897,0.0028352388,0.00005587947,0.0002978465,0.00024308672,0.00027474813,0.00011078109,0.000050195446,0.0006424789],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981999,0.00014717453,0.00021339773,0.00046711534,0.00036175794,0.00061065675],"domain_scores_gemma":[0.9988096,0.00016172449,0.000034067183,0.00061550975,0.000109693625,0.00026940354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037767628,0.00020376321,0.00014484253,0.0001156524,0.000350973,0.000067665846,0.00044644915,0.000049114336,0.000012022085],"category_scores_gemma":[0.00023530883,0.00016698522,0.000096934134,0.0005134885,0.0001562262,0.000015598376,0.00024095911,0.00018518927,0.00003530291],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014123764,0.0007389478,0.043017417,0.0012992017,0.00057770795,0.0009646339,0.005600677,0.33979678,0.11153471,0.00724415,0.0089455005,0.4661565],"study_design_scores_gemma":[0.0017813625,0.00036700087,0.22149245,0.00045025974,0.000096960015,0.000006230743,0.007034938,0.0065748338,0.0076989853,0.014746674,0.7383909,0.001359394],"about_ca_topic_score_codex":0.0000036439121,"about_ca_topic_score_gemma":0.000049302787,"teacher_disagreement_score":0.7294454,"about_ca_system_score_codex":0.000041176572,"about_ca_system_score_gemma":0.000105602165,"threshold_uncertainty_score":0.68094593},"labels":[],"label_agreement":null},{"id":"W4385403239","doi":"10.1101/2023.07.27.550902","title":"A multiplex, prime editing framework for identifying drug resistance variants at scale","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; Damon Runyon Cancer Research Foundation; Massachusetts Institute of Technology; Natural Sciences and Engineering Research Council of Canada; Karolinska Institutet; Harvard University; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Multiplex; Genome editing; Genome; Computational biology; Biology; Genetics; CRISPR; Context (archaeology); Gene; Prime (order theory)","score_opus":0.017550695170211617,"score_gpt":0.2825491019750334,"score_spread":0.2649984068048218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385403239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64306134,0.003505181,0.34618217,0.0002936723,0.0044615567,0.0014198194,0.0006513433,0.00041777955,0.0000071597387],"genre_scores_gemma":[0.9027433,0.00029747008,0.09327552,0.00009011994,0.002492229,0.0005502382,0.000006856657,0.0003094482,0.00023484048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968357,0.00006509743,0.00057795853,0.0014201992,0.0003132787,0.0007877719],"domain_scores_gemma":[0.99753314,0.00008715134,0.00034746388,0.0014568493,0.00032569352,0.0002497097],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00069073035,0.00058468035,0.0004927196,0.00014836423,0.0002968356,0.00017806157,0.00064916647,0.0007488763,0.000010322461],"category_scores_gemma":[0.0007753352,0.00071489,0.00029500574,0.00024227482,0.00008033109,0.0000081513035,0.0010768026,0.0004974949,0.000037536785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061352715,0.00004154244,0.0016773044,0.00074835576,0.00017705969,0.000012857211,0.000020822592,0.00038693225,0.99420166,0.00009234523,0.0025782515,0.0000015079713],"study_design_scores_gemma":[0.00054239033,0.000021432375,0.019142652,0.00089633296,0.00011172885,2.270844e-8,0.0000085845195,0.00054824824,0.96627396,0.000021418498,0.011498233,0.00093498535],"about_ca_topic_score_codex":0.00001666151,"about_ca_topic_score_gemma":0.00004510137,"teacher_disagreement_score":0.25968197,"about_ca_system_score_codex":0.00014396127,"about_ca_system_score_gemma":0.0002038846,"threshold_uncertainty_score":0.9995302},"labels":[],"label_agreement":null},{"id":"W4385415171","doi":"10.1080/21645698.2023.2239539","title":"Providing appropriate information to consumers boosts the acceptability of genome-edited foods in Japan","year":2023,"lang":"en","type":"article","venue":"GM crops & food","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Ministry of Health, British Columbia; Ministry of Education; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Christian ministry; Consumption (sociology); Business; Marketing; Health claims on food labels; Environmental health; Psychology; Medicine; Food science; Political science","score_opus":0.009034994852811383,"score_gpt":0.27819795131273123,"score_spread":0.26916295645991983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385415171","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708563,0.00010035676,0.0016601417,0.000160759,0.00012967679,0.00037370226,0.000030082083,0.000020518177,0.0004391485],"genre_scores_gemma":[0.9994989,0.000023300554,0.0002234613,0.000055478413,0.000041533753,0.000045051474,0.000081864106,0.000009460446,0.000020939968],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999279,0.000024559919,0.00024176728,0.00014284566,0.000103068065,0.00020873138],"domain_scores_gemma":[0.9995655,0.000012473137,0.000046069992,0.0002799524,0.000050492574,0.00004551615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028243728,0.00009704738,0.00010272977,0.00007905199,0.000038867536,0.00001912826,0.00016976205,0.000073794006,0.000014441723],"category_scores_gemma":[0.00014129918,0.00008064717,0.00004783737,0.00031842184,0.00003475031,0.000006457931,0.00013732833,0.0000692098,0.0000122405445],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019178628,0.00006633197,0.02920706,0.00031615858,0.00014379898,7.3810685e-7,0.0055989493,0.01550951,0.8213302,0.00011033687,0.00051188713,0.12701324],"study_design_scores_gemma":[0.00076023303,0.0005387285,0.6626301,0.000010425424,0.000018082721,0.0000035095295,0.0017822279,0.0007196898,0.309191,0.000055072414,0.024010496,0.00028047213],"about_ca_topic_score_codex":0.00004231422,"about_ca_topic_score_gemma":0.00010037212,"teacher_disagreement_score":0.63342303,"about_ca_system_score_codex":0.000013169866,"about_ca_system_score_gemma":0.00003712989,"threshold_uncertainty_score":0.32886964},"labels":[],"label_agreement":null},{"id":"W4385442585","doi":"10.1007/978-3-031-34567-8_6","title":"Canadian Regulatory Framework and Regulatory Requirements for Cell and Gene Therapy Products","year":2023,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Canada","funders":"","keywords":"Commercialization; Regulatory science; Harmonization; Risk analysis (engineering); Good manufacturing practice; Competence (human resources); Clinical trial; Product (mathematics); New product development; Medicine; Business; Biotechnology; Biology; Regulatory affairs; Marketing; Psychology","score_opus":0.045406590383329996,"score_gpt":0.4296664907265752,"score_spread":0.3842599003432452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385442585","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0091284895,0.989608,0.000038650902,0.000052258405,0.0004094746,0.00067883584,0.000024094863,0.000008115985,0.000052116196],"genre_scores_gemma":[0.0069594374,0.9911109,0.00077254284,0.00013515215,0.00049125234,0.00018036149,0.00021680265,0.000040851926,0.000092675305],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99872404,0.00004122897,0.0003043895,0.00059087796,0.00004009113,0.00029938604],"domain_scores_gemma":[0.9994934,0.000045019337,0.000083115796,0.0002311983,0.000017289807,0.00012995892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018059714,0.0002942012,0.0005882875,0.00013876468,0.00006041973,0.000005161115,0.000096622185,0.00032631165,0.0000026758623],"category_scores_gemma":[0.00005000125,0.00022970283,0.000033850345,0.00008622539,0.00024054539,0.00000472546,0.00007648456,0.00010912102,3.404487e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006556336,0.00004797186,0.0003654791,0.004596465,0.00013601167,0.000009059743,0.00036722174,0.0000010159121,0.051986177,0.00036111404,0.00053895434,0.941525],"study_design_scores_gemma":[0.0005829271,0.00083153136,0.000032880114,0.001051949,0.000034027507,0.000026782416,0.00020029067,0.0000014744127,0.009847256,0.00017821592,0.98690534,0.00030734183],"about_ca_topic_score_codex":0.00024186603,"about_ca_topic_score_gemma":0.00036675716,"teacher_disagreement_score":0.9863664,"about_ca_system_score_codex":0.000030343423,"about_ca_system_score_gemma":0.00007426441,"threshold_uncertainty_score":0.93670094},"labels":[],"label_agreement":null},{"id":"W4385575229","doi":"10.4324/9781003382102-8","title":"Potential of commercialization of genome-edited crops","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Commercialization; Biology; Business","score_opus":0.00956147983578467,"score_gpt":0.2653530082082903,"score_spread":0.2557915283725056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385575229","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011154423,0.0027707212,0.2779421,0.000115298615,0.0020334572,0.0008800427,0.0007346443,0.0000959562,0.70427334],"genre_scores_gemma":[0.34098837,0.0020338534,0.00085770205,0.000049581646,0.00076303113,0.000004821673,0.002513721,0.00014492887,0.652644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937814,0.0000038709745,0.00026157332,0.00016308046,0.000109888155,0.0000834499],"domain_scores_gemma":[0.99950695,0.0000034697493,0.000105111576,0.00024142895,0.000115275754,0.000027764445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051185238,0.00013189038,0.00019347895,0.000073400435,0.000011059389,0.0000025945717,0.000109907574,0.00026231777,0.00012122168],"category_scores_gemma":[0.00001125836,0.00013696223,0.00012012602,0.000020025718,0.000046019628,4.1722896e-7,0.000089388894,0.000049988186,0.000006666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004019631,0.000020387844,0.00003944275,0.00028593832,0.00027645877,0.000003252431,0.000027122154,0.0045501254,0.9814568,0.007543384,0.0038653342,0.0018915427],"study_design_scores_gemma":[0.001473709,0.0009337816,0.0042084176,0.00022354124,0.00046648335,0.000017622477,0.00005322399,0.00080248853,0.6496813,0.0019311918,0.33890542,0.0013027808],"about_ca_topic_score_codex":0.000012526747,"about_ca_topic_score_gemma":0.000018659683,"teacher_disagreement_score":0.3350401,"about_ca_system_score_codex":0.000003267192,"about_ca_system_score_gemma":0.000026494386,"threshold_uncertainty_score":0.5585158},"labels":[],"label_agreement":null},{"id":"W4385575270","doi":"10.4324/9781003382102-10","title":"Biosafety and biosecurity concerns associated with plant genome editing","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biosecurity; Biosafety; Biology; Biotechnology; Ecology","score_opus":0.013429184240249761,"score_gpt":0.25035835716080196,"score_spread":0.2369291729205522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385575270","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.026791804,0.006698997,0.005567346,0.0008835146,0.0014972838,0.0016389497,0.005600111,0.0006583779,0.9506636],"genre_scores_gemma":[0.52117574,0.002629792,0.0003544387,0.00021633033,0.0016870194,0.000016085285,0.0046652146,0.00024780925,0.46900755],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99908155,0.0000053798667,0.00017316792,0.0003972141,0.00012223917,0.00022046172],"domain_scores_gemma":[0.9995575,0.000017232649,0.000080140344,0.00020600737,0.00004886183,0.00009026711],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010256151,0.00026797105,0.00022749588,0.00004491421,0.000055640223,0.000021493626,0.000093395916,0.00035562227,0.000044312288],"category_scores_gemma":[0.000025250343,0.00023389969,0.000057757377,0.000016879056,0.000076486634,9.3630723e-7,0.00013554076,0.00016029117,0.000010491756],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007949489,0.00025982675,0.0022689295,0.0018645126,0.013846307,0.0012582651,0.0017541043,0.0018309199,0.68955094,0.21853724,0.056871038,0.011162951],"study_design_scores_gemma":[0.0048947767,0.0028513034,0.013361025,0.0013838161,0.00091114215,0.00025725504,0.00039595104,0.0007046407,0.06490766,0.0017388085,0.9026284,0.0059652072],"about_ca_topic_score_codex":0.0000082997285,"about_ca_topic_score_gemma":0.00021068784,"teacher_disagreement_score":0.84575737,"about_ca_system_score_codex":0.000012961367,"about_ca_system_score_gemma":0.000035831974,"threshold_uncertainty_score":0.9538153},"labels":[],"label_agreement":null},{"id":"W4385622484","doi":"10.1101/2023.08.07.552254","title":"Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Wellcome Trust","keywords":"DNA demethylation; Epigenetics; Embryonic stem cell; DNA methylation; Induced pluripotent stem cell; Demethylase; Histone; Biology; Cell biology; Downregulation and upregulation; Demethylation; Somatic cell; Molecular biology; Genetics; Gene expression; DNA; Gene","score_opus":0.01185870625569186,"score_gpt":0.25096620154728155,"score_spread":0.2391074952915897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385622484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9780423,0.0008713521,0.018944483,0.000045461933,0.001125344,0.00065284414,0.00015658366,0.00015916099,0.0000024368817],"genre_scores_gemma":[0.9959498,0.00076552265,0.0023157704,0.000035448847,0.0004296088,0.0002093938,0.000004502379,0.00019667098,0.00009328802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99730134,0.000104868224,0.00059838314,0.0010882255,0.00028745085,0.000619711],"domain_scores_gemma":[0.99827224,0.000025033976,0.0002613609,0.0010811685,0.00018805114,0.0001721173],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005854241,0.00055446604,0.0004268404,0.0002873387,0.00007311943,0.00009747956,0.00048337757,0.0007039957,0.000008357737],"category_scores_gemma":[0.000060732626,0.00066107605,0.00015844029,0.00032947617,0.000041792475,0.000010328926,0.0006081743,0.00053460774,0.000048291888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025961339,0.00006862702,0.0078088045,0.0002465389,0.000119342796,0.000013147245,0.0000071505647,0.0043938323,0.9871722,0.0000047362937,0.00013124809,0.000008408229],"study_design_scores_gemma":[0.00049876375,0.00007121842,0.01746237,0.00012301757,0.00003988111,1.208364e-8,0.0000057156076,0.002046397,0.9782117,6.8041106e-7,0.0008799511,0.0006602819],"about_ca_topic_score_codex":0.00005591823,"about_ca_topic_score_gemma":0.00003475487,"teacher_disagreement_score":0.017907461,"about_ca_system_score_codex":0.00014905215,"about_ca_system_score_gemma":0.00020615335,"threshold_uncertainty_score":0.999584},"labels":[],"label_agreement":null},{"id":"W4385651651","doi":"10.1098/rsob.230081","title":"Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m <sup>7</sup> G-cap-dependent translation at the 8- to 16-cell transition","year":2023,"lang":"en","type":"article","venue":"Open Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Ministerstvo Školství, Mládeže a Tělovýchovy; Akademie Věd České Republiky; Grantová Agentura České Republiky; Central European Institute of Technology; Jihočeská Univerzita v Českých Budějovicích","keywords":"Biology; Embryo; Translation (biology); Cell biology; Molecular biology; Genetics; Gene; Messenger RNA","score_opus":0.008508889185942382,"score_gpt":0.28711835950993225,"score_spread":0.27860947032398986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385651651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9699032,0.00025043794,0.028410558,0.00032376288,0.000042345746,0.00042769304,0.00031029645,0.00001095426,0.00032078332],"genre_scores_gemma":[0.99701494,0.00020820157,0.00024495364,0.00016962577,0.00004064681,0.000027691625,0.0014338655,0.000015250563,0.0008447991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927366,0.00006696198,0.00018304847,0.00026706664,0.000053694144,0.00015559982],"domain_scores_gemma":[0.9996999,0.000019226287,0.000043649765,0.00016306454,0.000030820123,0.000043339354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016077342,0.00010644264,0.000116678,0.00003498405,0.00008874949,0.000020706719,0.00012696059,0.00013485545,0.000050206614],"category_scores_gemma":[0.000003401973,0.00009207381,0.000032043426,0.000074603944,0.00003316236,0.000004560188,0.00007282875,0.0000436794,0.000013651788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012329257,0.0000131181405,0.00005572958,0.000015343714,0.000022072383,3.1847208e-7,0.0005429216,0.0057806317,0.98742115,0.0000031758216,0.0022219562,0.0038003004],"study_design_scores_gemma":[0.00057480467,0.00025623877,0.00020576012,0.000007410298,0.000022763232,0.0000074629465,0.00015226538,0.0020019645,0.99241525,0.000016910983,0.0042223833,0.000116798],"about_ca_topic_score_codex":0.0002796282,"about_ca_topic_score_gemma":0.00010288528,"teacher_disagreement_score":0.028165605,"about_ca_system_score_codex":0.0000109559805,"about_ca_system_score_gemma":0.00001290341,"threshold_uncertainty_score":0.3754661},"labels":[],"label_agreement":null},{"id":"W4385690508","doi":"10.1021/acschembio.3c00140","title":"Disrupting Protein Expression with Double-Clicked sgRNA–Cas9 Complexes: A Modular Approach to CRISPR Gene Editing","year":2023,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Cas9; Guide RNA; CRISPR; Subgenomic mRNA; Genome editing; Biology; RNA; Computational biology; Gene; Endonuclease; Nucleotide; Genetics","score_opus":0.017743312783671816,"score_gpt":0.317570560014017,"score_spread":0.2998272472303452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385690508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96759397,0.00013166638,0.030911617,0.00016288193,0.00007056601,0.0004540664,0.000021258704,0.00010666443,0.0005473353],"genre_scores_gemma":[0.9856446,0.0000113218575,0.012384703,0.00013887954,0.0006457942,0.00024920068,0.0007167111,0.000049586393,0.00015923513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830097,0.00003338261,0.0002763264,0.0006868642,0.00011798692,0.00058445404],"domain_scores_gemma":[0.99923325,0.00001847694,0.00006428517,0.0004338241,0.00006693787,0.00018320329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017829325,0.0002667168,0.00026818452,0.00007058502,0.00009038118,0.00002210526,0.00031595395,0.0002659129,0.0000059394215],"category_scores_gemma":[0.0000880984,0.00022125879,0.000070961636,0.00027532538,0.00009043368,0.0000038117744,0.00038685475,0.00017864385,0.00002661303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014084108,0.000042041454,0.00035545163,0.000041202344,0.000032515152,0.000003711262,0.00008511973,0.00046648702,0.9976766,0.00006392734,0.00042936986,0.0006627236],"study_design_scores_gemma":[0.00088300667,0.00015649226,0.00009082282,0.00003183231,0.000010889606,0.00002770447,0.00016736123,0.0003425506,0.9930081,0.000038997296,0.00493537,0.00030690676],"about_ca_topic_score_codex":0.00001867453,"about_ca_topic_score_gemma":0.000001654193,"teacher_disagreement_score":0.018526914,"about_ca_system_score_codex":0.000015720374,"about_ca_system_score_gemma":0.000022360055,"threshold_uncertainty_score":0.90226716},"labels":[],"label_agreement":null},{"id":"W4385691312","doi":"10.1021/acs.est.3c02492","title":"Genetic Engineering of <i>Acidithiobacillus ferridurans</i> Using CRISPR Systems To Mitigate Toxic Release in Biomining","year":2023,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Waterloo","funders":"Hospital for Sick Children; University of Toronto","keywords":"CRISPR; Acidithiobacillus; Cas9; Chemistry; Acidithiobacillus ferrooxidans; Computational biology; Gene; Materials science; Biology; Bioleaching; Metallurgy; Biochemistry","score_opus":0.006056774478126588,"score_gpt":0.24964583783457053,"score_spread":0.24358906335644395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385691312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991896,0.00050422415,0.00703204,0.00004963428,0.00021801876,0.00021834447,0.000015420545,0.000045063836,0.000021278403],"genre_scores_gemma":[0.9982535,0.000081741346,0.0015402499,0.000015543785,0.00003058055,0.000026684107,0.0000045632405,0.000020936872,0.00002617398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986072,0.000009143912,0.00026767355,0.00044777032,0.00019478428,0.00047343769],"domain_scores_gemma":[0.9994847,0.000005650994,0.000043302072,0.00035915404,0.0000065402082,0.000100655554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002163338,0.00015457429,0.00016444318,0.00064849394,0.00006393347,0.00001228491,0.00037745904,0.00013259544,0.000004309422],"category_scores_gemma":[0.000062277926,0.00017150839,0.000035423975,0.0012023418,0.00025927537,0.000006806704,0.00031655276,0.000091926115,0.0000164552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004004354,0.000012356482,0.0058089797,0.000010569701,0.0000035800156,0.000011877434,0.000044322074,0.16447945,0.82871675,0.000008277075,0.000007723169,0.00089213246],"study_design_scores_gemma":[0.00023096937,0.00015335158,0.020012293,0.00004369938,0.000005997962,0.000050338782,0.00041077135,0.022440849,0.9555142,0.000005939645,0.0009029323,0.00022867718],"about_ca_topic_score_codex":0.000023144705,"about_ca_topic_score_gemma":0.0000055766586,"teacher_disagreement_score":0.1420386,"about_ca_system_score_codex":0.00008265823,"about_ca_system_score_gemma":0.00003309979,"threshold_uncertainty_score":0.69939095},"labels":[],"label_agreement":null},{"id":"W4385693897","doi":"10.1126/sciadv.adf4082","title":"FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Hôpital Maisonneuve-Rosemont; Université de Montréal; Université Laval; Hôtel-Dieu de Québec; McGill University; Jewish General Hospital","funders":"","keywords":"RAD51; DNA repair; DNA; DNA damage; Genome instability; Cell biology; Biology; Homologous recombination; Molecular biology; CRISPR; Computational biology; Genetics; Gene","score_opus":0.005252021046140698,"score_gpt":0.29761605812357117,"score_spread":0.29236403707743047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385693897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99825764,0.0003514075,0.00057949347,0.00013801806,0.0001343398,0.00014109796,0.0000047319113,0.000093858216,0.0002994162],"genre_scores_gemma":[0.9955518,0.000059400467,0.0031673773,0.00004650913,0.00007089308,0.000028243605,0.000006868065,0.000011878503,0.0010569846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989649,0.0000049138907,0.000090523674,0.00041236795,0.00018384017,0.00034344598],"domain_scores_gemma":[0.9995408,0.0000045951197,0.00001741272,0.0002668297,0.000060889906,0.00010945988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016564546,0.000105399195,0.00007744487,0.000066456916,0.00019337208,0.000038531325,0.0002371868,0.000021972437,0.000004135],"category_scores_gemma":[0.00009400155,0.00008314528,0.000024815437,0.0007285606,0.00012450699,0.000015549282,0.00011631708,0.000031596683,0.000028564511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016018259,0.000006305903,0.000979497,0.000016726557,0.0000036880892,0.000005151953,0.000093764786,0.010026275,0.98711395,0.0000069283074,0.00008719064,0.0016445114],"study_design_scores_gemma":[0.00012378974,0.00020159535,0.009332061,0.000027875649,0.0000026317603,0.000010310681,0.00015286698,0.00017760675,0.975346,0.000008323614,0.014454754,0.00016214716],"about_ca_topic_score_codex":0.0000024814192,"about_ca_topic_score_gemma":0.000028916853,"teacher_disagreement_score":0.014367563,"about_ca_system_score_codex":0.000009712065,"about_ca_system_score_gemma":0.00006041829,"threshold_uncertainty_score":0.3390566},"labels":[],"label_agreement":null},{"id":"W4385699872","doi":"10.1038/s41598-023-38897-x","title":"Foreign DNA detection in genome-edited potatoes by high-throughput sequencing","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Ministry of Agriculture, Forestry and Fisheries","keywords":"Genome; Gene; DNA sequencing; Biology; Genetics; Computational biology; Sequence assembly; CRISPR; Genome editing","score_opus":0.007883330489234447,"score_gpt":0.25735765013819356,"score_spread":0.2494743196489591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385699872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925482,0.00023158245,0.004367578,0.000023000086,0.0021773083,0.0001568186,0.000004819572,0.000056386278,0.00043429236],"genre_scores_gemma":[0.9979506,0.00002132294,0.00017000211,0.000015134804,0.00012484106,0.000025212115,0.00032210952,0.000019862417,0.0013509084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986038,0.000017937928,0.0002923859,0.00058459933,0.00018904476,0.0003122133],"domain_scores_gemma":[0.99935365,0.0000052619803,0.00007322397,0.00045255298,0.00005030783,0.0000650186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006167587,0.00011611778,0.00010402436,0.00014273889,0.00011019028,0.000071219554,0.00008145011,0.00009475772,0.000015857535],"category_scores_gemma":[0.00009624083,0.00011874809,0.000051646868,0.0005393008,0.00006150737,0.000006065985,0.00007726302,0.00006467243,0.000014695624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029123228,0.000006616385,0.0005104418,0.000012559741,0.000007398067,0.00006870462,0.00006471416,0.0024180103,0.9931135,0.0000037838638,0.002860988,0.0009303799],"study_design_scores_gemma":[0.0001084044,0.000033017972,0.002296256,0.000008934156,0.0000048816746,0.00007332757,0.00014205881,0.00051802467,0.97608066,0.0007057225,0.019865273,0.0001634519],"about_ca_topic_score_codex":0.000058320744,"about_ca_topic_score_gemma":0.000094071496,"teacher_disagreement_score":0.017032843,"about_ca_system_score_codex":0.00003912697,"about_ca_system_score_gemma":0.000054051947,"threshold_uncertainty_score":0.48424065},"labels":[],"label_agreement":null},{"id":"W4385707526","doi":"10.17975/sfj-2023-006","title":"Comparison of Non-viral Delivery Vehicles for CRISPR/Cas9 Therapies","year":2023,"lang":"en","type":"article","venue":"STEM Fellowship Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Cas9; Viral vector; Computational biology; SAFER; Gene delivery; Genetic enhancement; Computer science; Biology; Gene; Genetics","score_opus":0.02859987965906615,"score_gpt":0.36080181195090505,"score_spread":0.3322019322918389,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385707526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97885925,0.0025405104,0.01778676,0.00009983331,0.000414989,0.00012517345,0.000015512087,0.000013538122,0.00014443004],"genre_scores_gemma":[0.997666,0.00031207906,0.0008950975,0.000029969588,0.0004152443,0.0000091247175,0.000018622603,0.000026294643,0.0006275862],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991344,0.000026866282,0.00029643797,0.00014892184,0.00013354699,0.0002598005],"domain_scores_gemma":[0.99952614,0.00003187611,0.00010093035,0.00015884238,0.00010694357,0.00007525324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030487304,0.0001264038,0.00019708826,0.00007864702,0.00010524589,0.000029678056,0.00018687846,0.000100277786,0.0000068593636],"category_scores_gemma":[0.000018320332,0.000114734816,0.00017810427,0.00008511447,0.00004032571,0.000003993887,0.000048111215,0.00011015791,0.00000697523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119116085,0.000036185087,0.013532398,0.00007251465,0.00013025712,0.0000033464935,0.00061041815,0.0027755825,0.956799,0.00001598748,0.012067198,0.013838001],"study_design_scores_gemma":[0.0010244629,0.0006728707,0.01153752,0.00005717777,0.000047063368,0.00003307671,0.0028587347,0.0037783973,0.9571116,0.00013573882,0.022478802,0.0002645518],"about_ca_topic_score_codex":0.000002432104,"about_ca_topic_score_gemma":0.0000054802636,"teacher_disagreement_score":0.018806728,"about_ca_system_score_codex":0.000007822736,"about_ca_system_score_gemma":0.00004506808,"threshold_uncertainty_score":0.467875},"labels":[],"label_agreement":null},{"id":"W4385778890","doi":"10.1111/pbi.14156","title":"Directed evolution rice genes with randomly multiplexed sgRNAs assembly of base editors","year":2023,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"Chinese Academy of Agricultural Sciences; Natural Science Foundation of Jiangsu Province; Nanjing Agricultural University; Government of Jiangsu Province; Jiangsu Agricultural Science and Technology Innovation Fund","keywords":"Biology; Gene; Computational biology; Genetics; Base (topology); Biotechnology; Evolutionary biology","score_opus":0.005866284654762564,"score_gpt":0.2385690086448978,"score_spread":0.23270272399013522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385778890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9811832,0.0015710181,0.015567058,0.0005175271,0.0008224904,0.00012059711,0.000050222723,0.00013138218,0.0000365257],"genre_scores_gemma":[0.9956319,0.0013291676,0.0020784119,0.000010848295,0.0007388071,0.00000806508,0.000078650264,0.00002263031,0.00010152886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990759,0.000035260284,0.00024171291,0.00020843456,0.00014703517,0.00029169032],"domain_scores_gemma":[0.9994805,0.000029133816,0.00013009801,0.00020771172,0.000085572,0.00006699296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002463167,0.00015117628,0.00019436526,0.0002557545,0.00009573497,0.000010844013,0.00020044946,0.00033057207,0.0000044187873],"category_scores_gemma":[0.00013863032,0.00012163742,0.000069379705,0.00031837882,0.00008671241,0.000003859402,0.00006587676,0.00023575625,0.000006333092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025769198,0.000027249327,0.0011792739,0.000016891787,0.00010789994,0.00003838911,0.000013323982,0.0011194799,0.9919981,0.000012658124,0.0042039948,0.001025098],"study_design_scores_gemma":[0.0017653838,0.00033038817,0.0043081,0.00003645244,0.000040487892,0.0007124715,0.00011215225,0.0015728315,0.9794772,0.000014494538,0.0114490045,0.0001810063],"about_ca_topic_score_codex":0.000014232538,"about_ca_topic_score_gemma":0.000023242901,"teacher_disagreement_score":0.014448712,"about_ca_system_score_codex":0.000015322534,"about_ca_system_score_gemma":0.00006491452,"threshold_uncertainty_score":0.49602303},"labels":[],"label_agreement":null},{"id":"W4385837901","doi":"10.1101/2023.08.14.553307","title":"Intein-based thermoregulated meganucleases for biocontainment of genetic material","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Intein; Homing endonuclease; Plasmid; Escherichia coli; Biology; Endonuclease; Synthetic biology; DNA; Genetics; Computational biology; Gene; RNA splicing","score_opus":0.010324517028183364,"score_gpt":0.24570638781399773,"score_spread":0.23538187078581435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385837901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9697108,0.00067807327,0.02638836,0.00006758201,0.0011137094,0.0010059982,0.0009067793,0.00012767769,9.871374e-7],"genre_scores_gemma":[0.9909192,0.00009149488,0.007888067,0.000056882112,0.00050365704,0.00033034346,0.000007880086,0.00019409796,0.000008380092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805933,0.000048545513,0.0005246244,0.0007583686,0.00019411434,0.00041502088],"domain_scores_gemma":[0.9982694,0.000023294953,0.00026052928,0.0010247636,0.0002819294,0.00014011649],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002442588,0.0004437388,0.0004350563,0.00015036545,0.000055115648,0.000054071515,0.00044426587,0.00048113076,0.000019605935],"category_scores_gemma":[0.00012859178,0.0004809407,0.00025005173,0.00013249129,0.00009644296,0.0000019503957,0.00031866448,0.00013274715,0.00000567852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014602693,0.00007134931,0.0006188226,0.0005359724,0.00020250474,0.0000054700577,0.000002166323,0.0034521925,0.99456763,0.000019452878,0.00037353943,0.0000048592196],"study_design_scores_gemma":[0.0006177056,0.00021750055,0.028880164,0.00018946937,0.00012059368,8.230015e-9,0.000002062856,0.0013263463,0.96611655,0.0000017240999,0.0020282357,0.00049966184],"about_ca_topic_score_codex":0.00003657957,"about_ca_topic_score_gemma":0.0000031413806,"teacher_disagreement_score":0.028451115,"about_ca_system_score_codex":0.000050827908,"about_ca_system_score_gemma":0.00028620276,"threshold_uncertainty_score":0.9997642},"labels":[],"label_agreement":null},{"id":"W4385880558","doi":"10.1016/j.heliyon.2023.e19173","title":"Costa Rican consumer perceptions of gene-editing","year":2023,"lang":"en","type":"article","venue":"Heliyon","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona; Universidad de Costa Rica","keywords":"Agriculture; Food security; Sustainability; Perception; Biotechnology; Geography; Socioeconomics; Marketing; Psychology; Biology; Business; Sociology; Ecology","score_opus":0.009905607174955726,"score_gpt":0.3003674447774593,"score_spread":0.2904618376025036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385880558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99265164,0.0008083934,0.005314302,0.000060088696,0.00013835516,0.00005927862,0.000042115316,0.000026264912,0.0008995372],"genre_scores_gemma":[0.99737763,0.000994593,0.0009718991,0.000035965735,0.00016093602,0.000008742511,0.00013023913,0.000013852829,0.0003061342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995597,0.000008413534,0.0001053785,0.00012804208,0.00006331441,0.00013516763],"domain_scores_gemma":[0.9997319,0.0000067889755,0.000021720769,0.00016515279,0.00003565767,0.000038798607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006429932,0.000060914692,0.00006686609,0.00003945138,0.000030943018,0.0000044082053,0.00006313917,0.00005126173,0.000025223053],"category_scores_gemma":[0.000040444043,0.00006367829,0.000045925844,0.00010573709,0.000029926417,7.5069045e-7,0.000036522797,0.00003546283,0.00002812214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000031341872,0.0000070026845,0.006995484,0.000041625553,0.000012846243,0.0000010601841,0.000046704994,0.0003830301,0.98928165,0.000013786529,0.0015997359,0.001613961],"study_design_scores_gemma":[0.00027742013,0.000083219864,0.05716795,0.000038126087,0.000016727643,0.000010601611,0.00039145106,0.00021354882,0.91825527,0.0000076866045,0.02339098,0.00014699207],"about_ca_topic_score_codex":0.0000041553208,"about_ca_topic_score_gemma":0.000013856172,"teacher_disagreement_score":0.07102633,"about_ca_system_score_codex":0.0000034036957,"about_ca_system_score_gemma":0.000013613973,"threshold_uncertainty_score":0.25967255},"labels":[],"label_agreement":null},{"id":"W4385933254","doi":"10.1016/j.ymthe.2023.07.019","title":"Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences","year":2023,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; NYU Grossman School of Medicine; Fundação Oswaldo Cruz; Directorate for Biological Sciences; School of Medicine, Indiana University; University of Health and Allied Sciences; Institut National Du Cancer; Indian Institute of Technology Kanpur; Conselho Nacional de Desenvolvimento Científico e Tecnológico; University of Southampton; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; University of California, San Francisco; Muhimbili University of Health and Allied Sciences; York University","keywords":"Genetic enhancement; Biomedical sciences; Medicine; Gene; Medical education; Biology; Genetics; Nursing","score_opus":0.02024739504006841,"score_gpt":0.3324861004986957,"score_spread":0.3122387054586273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385933254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9138281,0.038154826,0.0044813734,0.042654738,0.000097074735,0.0006346759,0.00009175054,0.000008509353,0.00004899885],"genre_scores_gemma":[0.7768312,0.082024336,0.0017970485,0.136734,0.00031682395,0.0000305293,0.0017501974,0.00011048544,0.00040537876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992734,0.00012192101,0.0001351548,0.00023290598,0.00011700343,0.00011959055],"domain_scores_gemma":[0.99961835,0.000016207887,0.00014564538,0.00015471264,0.00004543837,0.000019661793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020233796,0.00012012927,0.0001501221,0.00004455713,0.00007240027,0.000009358465,0.0001234979,0.0001089871,0.000004974762],"category_scores_gemma":[0.000003955893,0.0001022621,0.000043071606,0.00008710259,0.00016669775,0.0000019757997,0.000027598686,0.00009115943,1.6101323e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004043875,0.000045595534,0.00084217713,0.00010691628,0.00034190709,0.0000021473004,0.0022167107,0.000025911317,0.8179436,0.000020860409,0.086698875,0.09171492],"study_design_scores_gemma":[0.0014552627,0.0016660978,0.0031606825,0.00004808481,0.000023290453,0.00001008188,0.003774058,0.000021173277,0.68992656,0.00020317009,0.29934976,0.00036179187],"about_ca_topic_score_codex":0.00027408748,"about_ca_topic_score_gemma":0.000012734904,"teacher_disagreement_score":0.21265088,"about_ca_system_score_codex":0.0000074055893,"about_ca_system_score_gemma":0.00021923496,"threshold_uncertainty_score":0.41701275},"labels":[],"label_agreement":null},{"id":"W4386055654","doi":"10.1186/s43897-023-00065-0","title":"Efficient and transgene-free genome editing in banana using a REG-2 promoter–driven gene-deletion system","year":2023,"lang":"en","type":"letter","venue":"Molecular Horticulture","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Guangzhou Municipal Science and Technology Bureau; National Natural Science Foundation of China; Shanghai Jiao Tong University; University of Connecticut","keywords":"Transgene; Genome editing; Gene; Genome; Genetics; Computational biology; Biology","score_opus":0.007048768709130676,"score_gpt":0.24201361979419653,"score_spread":0.23496485108506585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386055654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96306103,0.0045908717,0.018781487,0.011426902,0.00058567117,0.0011660797,0.00019602638,0.00011997855,0.00007195357],"genre_scores_gemma":[0.9737206,0.00018628515,0.004738746,0.013140555,0.005176916,0.00021295426,0.0019920408,0.00044147903,0.00039041415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975804,0.00010318023,0.00046081695,0.00088878936,0.00035707036,0.00060970493],"domain_scores_gemma":[0.99901146,0.0000057522343,0.00013229554,0.0006667788,0.000090306065,0.000093420844],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001693285,0.0004944136,0.00043622789,0.00016011791,0.00009147711,0.000072597904,0.00032887174,0.0010446917,0.0000017885],"category_scores_gemma":[0.00004778498,0.0004801428,0.00019629045,0.00024668613,0.000051751238,0.0000019502668,0.00019671711,0.00066168205,0.0000037255702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000951126,0.000015063326,0.000027194243,0.00065994915,0.00013537049,0.0012081431,0.00018669013,0.06113584,0.92913693,0.000002493588,0.007397237,0.000085549786],"study_design_scores_gemma":[0.0056684213,0.000939185,0.0025680575,0.0029514292,0.0013506952,0.002914346,0.0013194126,0.12804283,0.666792,0.000035014367,0.180732,0.006686655],"about_ca_topic_score_codex":0.000042638698,"about_ca_topic_score_gemma":0.000047576814,"teacher_disagreement_score":0.26234502,"about_ca_system_score_codex":0.00009995953,"about_ca_system_score_gemma":0.000050533858,"threshold_uncertainty_score":0.99976504},"labels":[],"label_agreement":null},{"id":"W4386077183","doi":"10.1080/14636778.2023.2248363","title":"Siloed discourses: a year-long study of twitter engagement on the use of CRISPR in food and agriculture","year":2023,"lang":"en","type":"article","venue":"New Genetics and Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Horizon 2020; European Commission","keywords":"CRISPR; Skepticism; Agriculture; Work (physics); Public relations; Civil society; Emerging technologies; Political science; Sociology; Internet privacy; Biology; Computer science; Politics; Epistemology; Engineering; Law; Gene; Ecology","score_opus":0.03699395140392055,"score_gpt":0.3089875160764588,"score_spread":0.27199356467253827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386077183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989999,0.00034382893,0.00023503051,0.00013550697,0.00003152008,0.00022647184,0.000007346705,0.00000286123,0.00001756368],"genre_scores_gemma":[0.9985631,0.00091125036,0.00026989667,0.00006630424,0.000043499902,0.000007706538,0.0000068038503,0.000008437957,0.00012296175],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994904,0.000026995123,0.00012697658,0.00015724808,0.00009345181,0.00010492545],"domain_scores_gemma":[0.9997345,0.000024125857,0.000031167885,0.00015897691,0.00001990008,0.000031305655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010669055,0.00008559707,0.00009836283,0.000012658855,0.000029795106,0.000013150604,0.000057317404,0.000058233418,0.000001932565],"category_scores_gemma":[0.000014900663,0.00005862522,0.000041344523,0.00009100139,0.000030206947,0.0000010770088,0.00010245007,0.0000697713,1.5686582e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055210083,0.00054173695,0.13147849,0.00018097767,0.0005453133,0.0000029054559,0.031012654,0.0105305035,0.7896867,0.00016110665,0.031299613,0.0045048213],"study_design_scores_gemma":[0.0022568773,0.002314449,0.8096851,0.00005989093,0.00007526258,0.0000016462131,0.022456815,0.00082667696,0.15850195,0.000070326765,0.0034288415,0.00032214087],"about_ca_topic_score_codex":0.000025513518,"about_ca_topic_score_gemma":0.00007604448,"teacher_disagreement_score":0.6782066,"about_ca_system_score_codex":0.0000021906797,"about_ca_system_score_gemma":0.000011543875,"threshold_uncertainty_score":0.23906672},"labels":[],"label_agreement":null},{"id":"W4386156636","doi":"10.3389/fpls.2023.1273980","title":"Editorial: CRISPR-based genome editing for seed oil improvements in Brassica napus L.","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Brassica; Biology; Genome editing; Genome; Computational biology; Genetics; Biotechnology; Gene; Botany","score_opus":0.005007725523054383,"score_gpt":0.275145998101536,"score_spread":0.2701382725784816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386156636","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008923933,0.000274454,0.009709283,0.00002780023,0.9877183,0.0002468376,0.0010477292,0.000028884415,0.000054361913],"genre_scores_gemma":[0.0012186277,0.00021582276,0.004139686,0.000021616162,0.99197423,0.00019975955,0.0017217173,0.00006700711,0.00044151384],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99699986,0.000023605779,0.0004364651,0.00095772144,0.0007446944,0.0008376419],"domain_scores_gemma":[0.9990525,0.00010686964,0.0001527122,0.00040838154,0.00014820597,0.00013129851],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012926387,0.00032645318,0.00037489572,0.00044490173,0.000116563264,0.000095151074,0.0008900193,0.00062670285,7.5040583e-7],"category_scores_gemma":[0.0019719545,0.00035437135,0.00009400834,0.00048740246,0.00017173859,0.000010149701,0.00019254704,0.00041598058,0.0000021398776],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007390012,0.00002592553,0.0001719533,0.00013640929,0.000010884673,0.0000049869973,0.000028945537,0.0014053695,0.08126485,3.9447167e-7,0.91640425,0.00047215863],"study_design_scores_gemma":[0.0012078498,0.00016919074,0.000086747095,0.00013878962,0.000013784809,2.4487983e-7,0.00007840979,0.0026954636,0.01629302,0.000017062523,0.9788482,0.00045124465],"about_ca_topic_score_codex":0.00007424717,"about_ca_topic_score_gemma":0.00012964851,"teacher_disagreement_score":0.064971834,"about_ca_system_score_codex":0.00018872767,"about_ca_system_score_gemma":0.0008299299,"threshold_uncertainty_score":0.9998908},"labels":[],"label_agreement":null},{"id":"W4386204438","doi":"10.1016/j.mrrev.2023.108466","title":"Error-corrected next generation sequencing – Promises and challenges for genotoxicity and cancer risk assessment","year":2023,"lang":"en","type":"review","venue":"Mutation Research/Reviews in Mutation Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Mutagenesis; Computational biology; Genotoxicity; Risk assessment; Gene mutation; Carcinogen; Cancer; Biology; Mechanism (biology); DNA sequencing; Mutation; Bioinformatics; Risk analysis (engineering); Computer science; Genetics; Gene; Medicine; Toxicity","score_opus":0.5645337369604767,"score_gpt":0.573689100870328,"score_spread":0.009155363909851277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386204438","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033934985,0.98841983,0.0015435591,0.00013811131,0.0001367755,0.0061700684,0.00012249211,0.000022864479,0.00005282684],"genre_scores_gemma":[0.0005351029,0.9879244,0.0018003463,0.000008325005,0.00042391501,0.007944277,0.0009391934,0.00009929652,0.0003251682],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99366623,0.0029080315,0.0009046251,0.0011026057,0.0006928149,0.00072566274],"domain_scores_gemma":[0.99757385,0.00083575264,0.00023863914,0.00041188917,0.00075247977,0.00018736193],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.010635701,0.00036789948,0.00086217764,0.0009283215,0.00044722835,0.00024864686,0.00026499046,0.000461751,0.000012124361],"category_scores_gemma":[0.0035211574,0.00033508823,0.00012935464,0.0008505066,0.00021836578,0.000028187767,0.000262046,0.0009883465,0.000009918901],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013410537,0.000027715701,0.000014548641,0.017589578,0.000078940655,0.000009120786,0.0003562997,0.0002723628,0.0014041153,0.00004465598,0.00046082566,0.9797284],"study_design_scores_gemma":[0.00093132723,0.0006237049,0.0003054086,0.0066831606,0.00015191901,0.000036297042,0.0011989105,0.02197698,0.00068497,0.00033501815,0.9663223,0.0007499861],"about_ca_topic_score_codex":0.00031390908,"about_ca_topic_score_gemma":0.001758183,"teacher_disagreement_score":0.97897846,"about_ca_system_score_codex":0.00034562591,"about_ca_system_score_gemma":0.0008509417,"threshold_uncertainty_score":0.9999101},"labels":[],"label_agreement":null},{"id":"W4386215945","doi":"10.1038/s41587-023-01910-9","title":"Strand-preferred base editing of organellar and nuclear genomes using CyDENT","year":2023,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Genome editing; RNA editing; Transcription activator-like effector nuclease; Biology; Cytidine deaminase; Computational biology; Cas9; DNA; CRISPR; Genetics; Gene; RNA","score_opus":0.007120003430360656,"score_gpt":0.2765296464187992,"score_spread":0.2694096429884385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386215945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99544984,0.0033576956,0.00046420423,0.0002849099,0.00020219127,0.000084264255,0.00001922174,0.00006947827,0.00006819177],"genre_scores_gemma":[0.9971532,0.0008222132,0.0017599739,0.00004178376,0.0001368625,0.0000010324972,0.000027020867,0.000024059547,0.00003383752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993387,0.000009837446,0.00013281388,0.00025466,0.00006871725,0.00019529223],"domain_scores_gemma":[0.9996481,0.0000068234845,0.000042214982,0.00023857955,0.000029799809,0.00003450542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009399673,0.00011025272,0.00013418496,0.00012420358,0.000042315543,0.000006030472,0.00013013241,0.00076421717,0.000009061523],"category_scores_gemma":[0.000074192765,0.00011059469,0.00003617092,0.00019913877,0.000082467835,0.0000014376775,0.00016518668,0.00023485174,0.0000023367215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010730611,0.0000071545915,0.00034768085,0.0000350521,0.000029477553,0.000006367852,0.000025576413,0.00014634679,0.9963177,0.00022831174,0.00023889892,0.0026066962],"study_design_scores_gemma":[0.00034699464,0.00011403744,0.00068426505,0.000016097452,0.00002130251,0.000047404457,0.00026664144,0.0014495723,0.97700703,0.00006376259,0.019835938,0.00014696713],"about_ca_topic_score_codex":0.0000033012318,"about_ca_topic_score_gemma":0.000004535079,"teacher_disagreement_score":0.019597039,"about_ca_system_score_codex":0.000005498109,"about_ca_system_score_gemma":0.000014143594,"threshold_uncertainty_score":0.58943427},"labels":[],"label_agreement":null},{"id":"W4386221531","doi":"10.3390/ijms241713241","title":"Effects of sgRNAs, Promoters, and Explants on the Gene Editing Efficiency of the CRISPR/Cas9 System in Chinese Kale","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Sichuan Province; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Genome editing; Biology; Mutant; Genetics; Gene; Subgenomic mRNA","score_opus":0.005346856664982523,"score_gpt":0.2820245533122064,"score_spread":0.27667769664722386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386221531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973769,0.0006600905,0.0011045327,0.0002545811,0.00046451783,0.000073304866,0.000002788796,0.0000013433495,0.00006195185],"genre_scores_gemma":[0.99970007,0.00006962739,0.00011115583,0.000029620922,0.000079346384,0.0000016993805,3.983304e-7,0.0000034029672,0.000004698846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918807,0.000049137296,0.00021474989,0.000092407216,0.00037007863,0.00008555961],"domain_scores_gemma":[0.9996101,0.000053624568,0.00016622235,0.00007081086,0.00008066605,0.000018565119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005282129,0.000061090526,0.00008486749,0.00009490458,0.000028922264,0.000014539693,0.0004327214,0.000025731682,4.9392185e-7],"category_scores_gemma":[0.00023786859,0.000033650213,0.00005907311,0.00017418829,0.00008446472,0.0000044001913,0.00009729912,0.000059194295,1.972406e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011855746,0.000019499934,0.004052914,0.000024961651,0.000022031105,0.000021181433,0.00016992807,0.0038253244,0.9912737,0.00009671764,0.000020897594,0.00046098643],"study_design_scores_gemma":[0.00023708376,0.00013818113,0.02205291,0.00019398774,0.0000051619354,0.000076802404,0.00023521762,0.0011820102,0.97577727,0.000038979888,0.000024625782,0.000037758076],"about_ca_topic_score_codex":0.000007386396,"about_ca_topic_score_gemma":0.000001975542,"teacher_disagreement_score":0.017999997,"about_ca_system_score_codex":0.0000069864222,"about_ca_system_score_gemma":0.00003676773,"threshold_uncertainty_score":0.13722157},"labels":[],"label_agreement":null},{"id":"W4386253069","doi":"10.20944/preprints202308.1828.v1","title":"Engineered Expression of the Vip3A in Green Tissues as a Feasible approach for Control of Insect Pests in Maize","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Zhejiang University; China Agricultural University; South China Agricultural University; National Natural Science Foundation of China","keywords":"Biology; Transgene; Genetically modified crops; Gene; Biotechnology; Biosafety; Hybrid; Spodoptera; Agronomy; Genetics; Recombinant DNA","score_opus":0.06938865946230623,"score_gpt":0.35439709999294133,"score_spread":0.2850084405306351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386253069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98864424,0.0005271088,0.009038558,0.000045149984,0.0001664635,0.0011944647,0.00006455761,0.000014878081,0.00030458768],"genre_scores_gemma":[0.99788755,0.00012815412,0.000931043,0.000009597856,0.000071866445,0.00034867105,0.00006960221,0.000042843545,0.0005106927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985322,0.00007610848,0.00047013393,0.00053199235,0.00015684695,0.00023272904],"domain_scores_gemma":[0.9988512,0.000037103,0.00016583041,0.00083656097,0.00006915229,0.000040162282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004713674,0.00022560901,0.00040268697,0.0001263341,0.000012817417,0.0000032767718,0.00052434776,0.00035785706,0.00001038573],"category_scores_gemma":[0.00032536543,0.00020124101,0.00019098191,0.00012478988,0.00004386828,0.000001956367,0.0007942478,0.00026298958,0.0000027350823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014932522,0.00009818012,0.15960915,0.00065302104,0.000040922754,8.918658e-7,0.00029390483,0.07007974,0.76894206,0.000011756343,0.000009665655,0.00011141059],"study_design_scores_gemma":[0.0010053205,0.00003571573,0.19835514,0.0002456056,0.000019212654,0.0000017428351,0.000059031197,0.00238053,0.7973659,0.00018795114,0.00016463337,0.0001791945],"about_ca_topic_score_codex":0.00047378216,"about_ca_topic_score_gemma":0.00009673173,"teacher_disagreement_score":0.06769921,"about_ca_system_score_codex":0.00002361259,"about_ca_system_score_gemma":0.000099858255,"threshold_uncertainty_score":0.82063705},"labels":[],"label_agreement":null},{"id":"W4386437954","doi":"10.1007/978-1-0716-3401-1_19","title":"Mutation Knock-in Methods Using Single-Stranded DNA and Gene Editing Tools in Zebrafish","year":2023,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"CRISPR; Cas9; Genome editing; Zebrafish; Computational biology; DNA; Guide RNA; Point mutation; Mutant; Biology; Gene knockin; Genetics; Gene","score_opus":0.09629697185933733,"score_gpt":0.5185088781259714,"score_spread":0.422211906266634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386437954","genre_codex":"review","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011650246,0.503618,0.49433172,0.00000632369,0.00034061275,0.00046255134,0.000017283077,0.00001441216,0.000044104898],"genre_scores_gemma":[0.000034486246,0.38307285,0.6162052,0.000031750253,0.00017507077,0.000106526415,0.0002638873,0.000097363445,0.000012848183],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9946155,0.0026053772,0.0010743501,0.0010100135,0.00007468171,0.0006201024],"domain_scores_gemma":[0.99884987,0.0003635456,0.00023712812,0.00043679881,0.000034057124,0.00007863008],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0030970848,0.0005297953,0.0014395665,0.0006520252,0.000029247913,0.000037183498,0.00028796063,0.0010741985,0.000004085198],"category_scores_gemma":[0.0015439843,0.0005538917,0.00024627004,0.00069736125,0.00010067417,0.0000048120014,0.00029405137,0.00050552475,9.910483e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006753073,0.000024183972,0.000015910886,0.0010897014,0.000055737208,0.000074486146,0.000039117178,0.00032119107,0.41672418,0.000018731991,0.0000013429915,0.5816287],"study_design_scores_gemma":[0.003823505,0.0007910023,0.000111883,0.008771719,0.000737334,0.00089928095,0.00029415908,0.0042389133,0.66879976,0.0031843763,0.3044936,0.0038544494],"about_ca_topic_score_codex":0.00004671803,"about_ca_topic_score_gemma":0.00008541627,"teacher_disagreement_score":0.5777742,"about_ca_system_score_codex":0.000091912865,"about_ca_system_score_gemma":0.000117059586,"threshold_uncertainty_score":0.99969125},"labels":[],"label_agreement":null},{"id":"W4386499154","doi":"10.1038/s41467-023-41143-7","title":"A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Mitacs; Government of Canada","keywords":"Cas9; CRISPR; Computer science; Nuclease; Genome editing; Genome engineering; Guide RNA; Computational biology; Artificial intelligence; Machine learning; Biology; DNA; Genetics","score_opus":0.03431413720950719,"score_gpt":0.34487756099178746,"score_spread":0.31056342378228025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386499154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8543335,0.0032806674,0.14058013,0.0004144577,0.00007801064,0.0002232359,0.00076908176,0.00012092147,0.00019996053],"genre_scores_gemma":[0.9674008,0.0008946165,0.02422407,0.000094047944,0.000051412375,0.00002427974,0.0070882887,0.000029230741,0.0001932869],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9992743,0.00007783761,0.00015836448,0.00021480858,0.00009695838,0.00017771605],"domain_scores_gemma":[0.99883306,0.000017862008,0.000024918285,0.001005179,0.0000629862,0.000055970013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021758208,0.00012273906,0.00010303361,0.000057545596,0.00024651558,0.000022587066,0.000371781,0.00020332573,0.0000031216337],"category_scores_gemma":[0.000038353344,0.000116379895,0.00003948094,0.00022860282,0.000044090357,0.0000051144366,0.00017351781,0.00042830667,0.0000024001322],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022853572,0.000034959,0.001461696,0.000017867056,0.000056481626,7.594292e-7,0.00007111499,0.6383947,0.358746,0.0003421631,0.00058757974,0.00026378827],"study_design_scores_gemma":[0.0010711204,0.0001307518,0.004713917,0.00004213826,0.00012409208,0.000033728098,0.000101096506,0.8582319,0.07210881,0.00006569487,0.0629018,0.00047496092],"about_ca_topic_score_codex":0.000118427146,"about_ca_topic_score_gemma":0.0010300858,"teacher_disagreement_score":0.2866372,"about_ca_system_score_codex":0.000015513893,"about_ca_system_score_gemma":0.000046506968,"threshold_uncertainty_score":0.47458345},"labels":[],"label_agreement":null},{"id":"W4386503008","doi":"10.1016/j.snb.2023.134568","title":"Ultrasensitive detection of methicillin-resistant Staphylococcus aureus using a T7 exonuclease-assisted PAM-free dual CRISPR-Cas12a biosensor","year":2023,"lang":"en","type":"article","venue":"Sensors and Actuators B Chemical","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Government of New Brunswick; Agriculture and Agri-Food Canada","funders":"","keywords":"Staphylococcus aureus; Metagenomics; Biosensor; Microbiology; Biology; Computational biology; Gene; Bacteria; Genetics; Biochemistry","score_opus":0.015316567205338867,"score_gpt":0.284498231829307,"score_spread":0.26918166462396814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386503008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99773717,0.00019757632,0.0014438344,0.00006561311,0.0001265953,0.00017111887,0.00015858898,0.000053677853,0.000045810026],"genre_scores_gemma":[0.9982051,0.00011725918,0.001267715,0.000041865263,0.00021631432,0.0000044610233,0.0000507414,0.000047390964,0.000049105714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852496,0.00005485245,0.00034272697,0.00047688538,0.00022373813,0.00037683302],"domain_scores_gemma":[0.9991346,0.000075538745,0.00010287553,0.00038839734,0.0001233396,0.00017523482],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018728437,0.00027084313,0.00030369617,0.00012259746,0.00008758862,0.000022054113,0.00009971586,0.00030216982,0.0000062721547],"category_scores_gemma":[0.0003759868,0.00026143726,0.00015796251,0.00028436125,0.00017471501,0.000004842832,0.00013168661,0.00018326554,0.0000031378563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017483911,0.00003578766,0.00004726144,0.00006512869,0.00009765485,0.000024125693,0.00013908165,0.00010602861,0.9973596,0.0000098004675,0.00014548357,0.0017952169],"study_design_scores_gemma":[0.000660173,0.00012090954,0.0012283672,0.00003167419,0.00007380121,0.000020415118,0.00048053332,0.0015214565,0.9945868,0.00004916339,0.00091487286,0.00031183477],"about_ca_topic_score_codex":0.00006295595,"about_ca_topic_score_gemma":0.000014495967,"teacher_disagreement_score":0.0027727925,"about_ca_system_score_codex":0.000022668883,"about_ca_system_score_gemma":0.000037127753,"threshold_uncertainty_score":0.9999838},"labels":[],"label_agreement":null},{"id":"W4386554093","doi":"10.21203/rs.3.rs-3253350/v1","title":"Investigation of the creatine biosynthesis negative feedback loop via creatine mediated control of arginine:glycine amidinotransferase expression in human HAP1 cells implies an intracellular creatine sensing mechanism","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Intracellular; Creatine; Extracellular; Arginine; Glycine; Cell biology; Homeostasis; Biochemistry; Biology; Chemistry; Biophysics; Amino acid","score_opus":0.03150243730764642,"score_gpt":0.3373210757147398,"score_spread":0.3058186384070934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386554093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98369694,0.0005338616,0.013452838,0.00026044517,0.00009839529,0.0014647527,0.00041862042,0.000031707354,0.00004243107],"genre_scores_gemma":[0.9970834,0.00044691624,0.0012478456,0.000010761888,0.00018432084,0.000059990933,0.00072443864,0.00009964917,0.00014265426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996161,0.0008678555,0.00089756964,0.00078387023,0.0007477255,0.0005419761],"domain_scores_gemma":[0.9973314,0.0004112197,0.00028536358,0.0010729752,0.0007112795,0.00018780935],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001491082,0.00044358862,0.0007100829,0.0004448972,0.00014032693,0.00003807681,0.00052139955,0.0005682314,0.00004314058],"category_scores_gemma":[0.00085617596,0.00036279057,0.0002052483,0.000556193,0.00037544183,0.000009596045,0.00053293223,0.0007790111,0.000002212811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025361337,0.00008132659,0.0014372453,0.0008513357,0.00010001529,0.000008767687,0.0007117525,0.0075080986,0.9887613,0.00002336653,0.000032948872,0.00023023525],"study_design_scores_gemma":[0.0012707592,0.00049724436,0.0059741284,0.0014648673,0.00005345301,0.0000021515061,0.0008168006,0.010327847,0.9786113,0.0006705163,0.000008708146,0.00030225675],"about_ca_topic_score_codex":0.00089302583,"about_ca_topic_score_gemma":0.00040986048,"teacher_disagreement_score":0.013386475,"about_ca_system_score_codex":0.00006239061,"about_ca_system_score_gemma":0.00020949297,"threshold_uncertainty_score":0.9998824},"labels":[],"label_agreement":null},{"id":"W4386587299","doi":"10.1101/2023.09.08.23295253","title":"Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Health and Medical Research Council; Medical Research Council; State Government of Victoria; American Heart Association","keywords":"Computational biology; Computer science; Genome editing; Pipeline (software); CRISPR; Phenotype; Base (topology); Biology; Genetics; Gene","score_opus":0.03321093573455705,"score_gpt":0.30826314144093747,"score_spread":0.27505220570638045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386587299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7919205,0.0013861803,0.20491388,0.00013405595,0.0011778104,0.0003390452,0.000022968752,0.000073943695,0.00003162176],"genre_scores_gemma":[0.9961204,0.00023146147,0.0020956188,0.000033792934,0.0009002966,0.000097294374,0.00026099698,0.0000851149,0.00017500977],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9982297,0.00007436427,0.00044754578,0.000778487,0.00015285479,0.00031707576],"domain_scores_gemma":[0.99901736,0.000025306888,0.000121854406,0.00066301384,0.00006397529,0.000108511114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00078598224,0.00033460933,0.00033453415,0.00010207495,0.000092532864,0.000074234784,0.00019998554,0.00034203145,0.0000040190084],"category_scores_gemma":[0.0003687783,0.00032418096,0.00013788971,0.00006071439,0.000031594285,0.0000023757063,0.0005737416,0.00034546776,0.000015081381],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025918725,0.000017739227,0.006182465,0.0007983473,0.000115857525,0.000012264735,0.00009272728,0.0552468,0.93412405,0.000043569886,0.000058797334,0.0032814415],"study_design_scores_gemma":[0.00089060015,0.00025434073,0.033875745,0.00028933905,0.0003030173,0.00003168397,0.000092841154,0.66715133,0.29478586,0.00064069865,0.0004454754,0.0012391058],"about_ca_topic_score_codex":0.000060365102,"about_ca_topic_score_gemma":0.000026544745,"teacher_disagreement_score":0.6393382,"about_ca_system_score_codex":0.000016867163,"about_ca_system_score_gemma":0.00003761339,"threshold_uncertainty_score":0.999921},"labels":[],"label_agreement":null},{"id":"W4386692101","doi":"10.1016/j.stemcr.2023.07.003","title":"Genome-wide loss-of-function screen using human pluripotent stem cells to study virus-host interactions for SARS-CoV-2","year":2023,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust","keywords":"Biology; Induced pluripotent stem cell; CRISPR; Embryonic stem cell; Genetic screen; Virus; Coronavirus; Virology; Genetics; Genome; Gene; Mutant; Disease; Infectious disease (medical specialty); Coronavirus disease 2019 (COVID-19)","score_opus":0.032964593725446155,"score_gpt":0.3270538139081871,"score_spread":0.294089220182741,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386692101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778867,0.000106420855,0.020254819,0.000007771661,0.00062780303,0.00088641944,0.000022955672,0.00003740332,0.0001697177],"genre_scores_gemma":[0.9983133,0.000008820791,0.00026712197,0.000029156781,0.00015849032,0.000057252037,0.00005397711,0.00004864278,0.0010632286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986042,0.000024786586,0.00049493555,0.0004592333,0.00015386402,0.00026301472],"domain_scores_gemma":[0.9991221,0.000014748105,0.00017479745,0.00050286716,0.0001190387,0.00006649284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028802105,0.0001818906,0.00020430265,0.00012751276,0.00012623942,0.00002502683,0.00009407183,0.000070188304,0.0000046814444],"category_scores_gemma":[0.000005200024,0.00019366831,0.00013868138,0.00018449836,0.00001494185,0.000004734162,0.00014076676,0.00006153882,0.000007000761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003557536,0.00009397529,0.0022435442,0.000046827034,0.000078599354,0.00003937387,0.0002228394,0.0046533793,0.9920772,4.648894e-7,0.00021805392,0.00029019147],"study_design_scores_gemma":[0.00022587474,0.0004502027,0.0056945547,0.000016536314,0.000075682416,0.000017126062,0.0004333438,0.000104778694,0.9777383,0.000004317673,0.015032331,0.00020690456],"about_ca_topic_score_codex":0.00008017417,"about_ca_topic_score_gemma":0.00010665688,"teacher_disagreement_score":0.020426622,"about_ca_system_score_codex":0.000029826158,"about_ca_system_score_gemma":0.00003380702,"threshold_uncertainty_score":0.7897564},"labels":[],"label_agreement":null},{"id":"W4386699575","doi":"10.1073/pnas.2306494120","title":"Sequencing 4.3 million mutations in wheat promoters to understand and modify gene expression","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Food and Agriculture; International Atomic Energy Agency; U.S. Department of Agriculture; Howard Hughes Medical Institute","keywords":"Biology; Genetics; RefSeq; Gene; Promoter; Nonsynonymous substitution; Functional genomics; Genomics; Mutation; Computational biology; Gene prediction; Gene expression; Genome","score_opus":0.04050934149834792,"score_gpt":0.33649041540111163,"score_spread":0.29598107390276374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386699575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99874,0.000076595825,0.000049039918,0.00079937454,0.000007907993,0.00010232365,0.000004859925,0.0000033342562,0.00021653925],"genre_scores_gemma":[0.997991,0.000042923763,0.0018562032,0.000043645363,0.00002004068,0.000004471541,3.796554e-7,0.0000023621365,0.00003896501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944085,0.0000020496364,0.00011112919,0.00014146845,0.00022340164,0.00008108754],"domain_scores_gemma":[0.99988174,0.000010247775,0.00003967472,0.0000048852353,0.000042495514,0.000020942036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034938563,0.000042182364,0.000047827656,0.00011422227,0.000056038538,0.000007911186,0.00013534774,0.000041156494,5.199149e-7],"category_scores_gemma":[0.00012257042,0.000031836888,0.00001567091,0.00037318637,0.000101507314,0.000009186071,0.0000826418,0.000035460223,1.677818e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000036005226,0.0000027070591,0.0011442336,0.000019583404,0.0000016067262,3.3934848e-9,0.0002494088,0.0046554473,0.99355197,0.00017763831,0.00009651585,0.00009730654],"study_design_scores_gemma":[0.000079293815,0.000028661363,0.017083215,0.000047636535,0.0000015562764,0.0000024114242,0.00053699594,0.0017530501,0.9780893,0.002318908,0.000019339417,0.00003965321],"about_ca_topic_score_codex":0.0000025011113,"about_ca_topic_score_gemma":2.0630512e-7,"teacher_disagreement_score":0.01593898,"about_ca_system_score_codex":0.000012340234,"about_ca_system_score_gemma":0.000014487615,"threshold_uncertainty_score":0.12982707},"labels":[],"label_agreement":null},{"id":"W4386710730","doi":"10.1038/s41531-023-00560-7","title":"Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)","year":2023,"lang":"en","type":"erratum","venue":"npj Parkinson s Disease","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institut Universitaire de Gériatrie de Montréal; Montreal Neurological Institute and Hospital","funders":"Barts Charity","keywords":"Parkinson's disease; Disease; Genetics; Medicine; Biology; Neuroscience; Bioinformatics; Internal medicine","score_opus":0.016239419436381134,"score_gpt":0.3205366931733472,"score_spread":0.3042972737369661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386710730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6355174,0.15308954,0.0048952806,0.005380689,0.15885003,0.018062724,0.012765686,0.0014351924,0.010003436],"genre_scores_gemma":[0.9599243,0.005581649,0.00087397854,0.00074997166,0.008077672,0.0028040407,0.009656724,0.0003617688,0.011969922],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.994244,0.0005720886,0.0010336533,0.0018921158,0.00095368107,0.0013044566],"domain_scores_gemma":[0.99705154,0.00007807779,0.00034638238,0.0015703626,0.00015412216,0.0007995188],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076279603,0.0010646585,0.00071715575,0.00025961394,0.00022478212,0.0002288267,0.0010944108,0.00079021533,0.000049196904],"category_scores_gemma":[0.00067637954,0.001017617,0.00044254732,0.0010807472,0.00018412575,0.000017438118,0.0004653431,0.0011137549,0.000054573396],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011164864,0.001403292,0.15922636,0.00069131446,0.00032339938,0.0032678542,0.0005326785,0.01219913,0.00015428664,0.000013606952,0.79318637,0.027885254],"study_design_scores_gemma":[0.0007156249,0.00016407207,0.41455492,0.00027981168,0.00017386474,0.000016901688,0.00021747239,0.008759349,0.000063002255,0.00009076958,0.57412344,0.00084074493],"about_ca_topic_score_codex":0.00037619748,"about_ca_topic_score_gemma":0.0021740375,"teacher_disagreement_score":0.32440683,"about_ca_system_score_codex":0.00034946535,"about_ca_system_score_gemma":0.0011736818,"threshold_uncertainty_score":0.9992274},"labels":[],"label_agreement":null},{"id":"W4386714937","doi":"10.1101/2023.09.12.557453","title":"Manufacturing DNA in E. coli yields higher fidelity DNA than <i>in vitro</i> enzymatic synthesis","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"DNA polymerase; DNA; Biology; Polymerase; DNA synthesis; Gene; DNA polymerase I; DNA replication; Computational biology; Molecular biology; Polymerase chain reaction; Genetics; Reverse transcriptase","score_opus":0.013194812225816702,"score_gpt":0.24313511737297652,"score_spread":0.22994030514715982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386714937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995938,0.00095983164,0.0007981295,0.00024382802,0.0011276118,0.0005944622,0.00016870514,0.00015052561,0.000018905706],"genre_scores_gemma":[0.9969583,0.00043457263,0.0014138647,0.00011548164,0.00044583497,0.00042038172,0.000002274032,0.00017853128,0.000030761512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968819,0.00013293933,0.00072866987,0.0011904693,0.00029163802,0.00077439257],"domain_scores_gemma":[0.99807763,0.00007616369,0.00019956497,0.0013788464,0.000067572044,0.000200196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00069272256,0.0006320326,0.0006531138,0.00031927385,0.000060054845,0.000106921674,0.00063048344,0.0008784719,0.00002360053],"category_scores_gemma":[0.00021541474,0.0007379658,0.00021191237,0.00027628476,0.00006495646,0.0000088873785,0.0007099676,0.00065863837,0.000041093856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053631367,0.0000818849,0.0018577382,0.0005186066,0.00008320798,0.00006438843,0.0000071451595,0.0013676328,0.99571466,0.000012144033,0.00023475595,0.0000041997],"study_design_scores_gemma":[0.0003077178,0.000019817555,0.1366363,0.00035090267,0.000039419472,1.8894564e-8,0.000003640068,0.00021288503,0.8600977,0.000003545462,0.0016488006,0.00067921914],"about_ca_topic_score_codex":0.00019969445,"about_ca_topic_score_gemma":0.00006266118,"teacher_disagreement_score":0.13561693,"about_ca_system_score_codex":0.00016786686,"about_ca_system_score_gemma":0.0002222303,"threshold_uncertainty_score":0.9995071},"labels":[],"label_agreement":null},{"id":"W4386764547","doi":"10.1525/elementa.2022.00143","title":"The knowledge politics of genome editing in Africa","year":2023,"lang":"en","type":"article","venue":"Elementa Science of the Anthropocene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"European Commission","keywords":"Genome editing; Politics; Scholarship; Narrative; Genome; Public relations; Political science; Sociology; Biology; Genetics","score_opus":0.014267118607363766,"score_gpt":0.3301989778575238,"score_spread":0.31593185925016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386764547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99627155,0.00086193153,0.00013591626,0.00038321712,0.0003527804,0.00010076859,0.000013591176,0.0000040485447,0.0018761815],"genre_scores_gemma":[0.9993833,0.00022969663,0.00009866187,0.0000060776633,0.00008015741,0.000002977653,0.0000023132739,0.000005015904,0.00019182704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925137,0.000014970439,0.00017450108,0.00012933055,0.0001570223,0.00027279402],"domain_scores_gemma":[0.99956644,0.000013846866,0.000054927204,0.0002873981,0.000052776784,0.000024609515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057515723,0.000054739565,0.000062067,0.00004551989,0.0001820251,0.000008310871,0.0005037222,0.000017856153,0.0000046541445],"category_scores_gemma":[0.000113075555,0.000035364596,0.00003606507,0.00055845344,0.000606866,0.0000026693754,0.00034463912,0.000035773686,0.0000017431256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000018494986,0.000022073404,0.0022431624,0.000012742077,0.0000050436074,1.9467214e-7,0.00017861929,0.00060285215,0.9954208,0.00028268836,0.0004186152,0.000811364],"study_design_scores_gemma":[0.0001592138,0.00007065756,0.027584126,0.0000180589,0.000004157801,0.0000015235926,0.0011248742,0.00080153777,0.96452236,0.00018614251,0.0054635103,0.000063808606],"about_ca_topic_score_codex":0.000014245916,"about_ca_topic_score_gemma":0.000017281995,"teacher_disagreement_score":0.030898407,"about_ca_system_score_codex":0.000013788664,"about_ca_system_score_gemma":0.00008193465,"threshold_uncertainty_score":0.2236023},"labels":[],"label_agreement":null},{"id":"W4386812964","doi":"10.1101/2023.09.16.558090","title":"Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Alberta; Stanford Diabetes Research Center","keywords":"CRISPR; Ribonucleoprotein; Genome editing; Cas9; Islet; Gene; Primary (astronomy); Biology; Cell biology; Molecular biology; Chemistry; Computational biology; Genetics; RNA; Physics; Biotechnology","score_opus":0.01016573895701852,"score_gpt":0.2403508848656922,"score_spread":0.23018514590867367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386812964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99291056,0.00077829935,0.004032146,0.00007794335,0.00076789886,0.0009443297,0.00024725485,0.00022787714,0.000013690719],"genre_scores_gemma":[0.98628044,0.00016211446,0.0114784865,0.00011589586,0.0013084488,0.0003169859,0.000009300736,0.00029864992,0.000029705436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967961,0.00008920368,0.0006035193,0.0013657319,0.0003526008,0.0007928678],"domain_scores_gemma":[0.9978753,0.000018766572,0.00027183394,0.0013800754,0.00022824707,0.000225831],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053346035,0.00069189107,0.00058199745,0.00027620545,0.00013460455,0.00012935087,0.00057395187,0.00071103236,0.000011030861],"category_scores_gemma":[0.000083673986,0.0007609289,0.00015346857,0.00034310066,0.00010664188,0.00000849932,0.0007778412,0.0007486389,0.00002902032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003485337,0.000080476544,0.0034371994,0.00041733665,0.00010893748,0.00013153575,0.000010350295,0.0038801054,0.9914421,0.0000073335104,0.00044795,0.0000018534266],"study_design_scores_gemma":[0.00089942955,0.00011481367,0.042851113,0.00032473632,0.000051272727,6.1528915e-8,0.000005992605,0.00022087195,0.95297205,5.3261493e-7,0.0016845983,0.0008745093],"about_ca_topic_score_codex":0.00020108682,"about_ca_topic_score_gemma":0.000057903766,"teacher_disagreement_score":0.039413914,"about_ca_system_score_codex":0.00014411045,"about_ca_system_score_gemma":0.00027464892,"threshold_uncertainty_score":0.9994842},"labels":[],"label_agreement":null},{"id":"W4386817664","doi":"10.15252/msb.202311933","title":"Turning up the heat on essential E. coli genes","year":2023,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Terry Fox Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Gene; Genetics; Computational biology","score_opus":0.008366491547167388,"score_gpt":0.3074858461062463,"score_spread":0.2991193545590789,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386817664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711724,0.0038180663,0.021385897,0.0002854206,0.0022137433,0.0003207711,0.000018776786,0.00007502932,0.0007098993],"genre_scores_gemma":[0.99803996,0.00016962251,0.00001609179,0.00019318365,0.0004756067,0.00008419826,0.00016448436,0.000034411292,0.00082241383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880767,0.00014751035,0.00020665195,0.00037311198,0.000094753166,0.00037030695],"domain_scores_gemma":[0.999368,0.000023347544,0.000033743323,0.00047070606,0.000043449716,0.00006074114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025211557,0.00018482636,0.00017015441,0.00006869994,0.00011775835,0.000031297586,0.000260264,0.00019634489,0.000006314714],"category_scores_gemma":[0.00005841163,0.00013730684,0.00011163355,0.00017464957,0.00007164334,8.772782e-7,0.00013379543,0.00010378764,0.00009768769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001886786,0.000006596666,0.00020886293,0.000017857481,0.00006942266,0.000012977012,0.000032710108,0.01630643,0.9799348,0.00063432136,0.0021970673,0.0005600638],"study_design_scores_gemma":[0.0005518753,0.00037165819,0.00091746025,0.000028808123,0.000029316825,0.00007009712,0.00019898286,0.004953388,0.81177187,0.00003706563,0.18069111,0.00037837913],"about_ca_topic_score_codex":0.00005362678,"about_ca_topic_score_gemma":0.0000073032793,"teacher_disagreement_score":0.17849405,"about_ca_system_score_codex":0.000009430896,"about_ca_system_score_gemma":0.00002815416,"threshold_uncertainty_score":0.5599211},"labels":[],"label_agreement":null},{"id":"W4386914078","doi":"10.3389/fpls.2023.1246905","title":"CRISPR/Cas9-mediated lipoxygenase gene-editing in yellow pea leads to major changes in fatty acid and flavor profiles","year":2023,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital; Agriculture and Agri-Food Canada; University of Saskatchewan; University of Calgary; National Research Council Canada","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Lipoxygenase; Polyunsaturated fatty acid; Food science; Hexanal; CRISPR; Biology; Biochemistry; Flavor; Gene; Chemistry; Fatty acid; Enzyme","score_opus":0.008227042363293297,"score_gpt":0.2615534587684355,"score_spread":0.2533264164051422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386914078","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960021,0.00051091146,0.0022629865,0.00030995812,0.00053018227,0.00024292037,0.00007063812,0.00001807799,0.000052248837],"genre_scores_gemma":[0.99446386,0.0003202938,0.004779869,0.00012940448,0.000095306255,0.000052122123,0.00007747402,0.000012263747,0.0000694171],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866843,0.000021557753,0.00017176197,0.00047593834,0.00017220121,0.00049008854],"domain_scores_gemma":[0.9996538,0.000013690828,0.000026707965,0.00017370479,0.000018334367,0.00011373811],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005630699,0.00013625289,0.00015418371,0.00046687125,0.000050962673,0.000031379266,0.00025290347,0.00008336428,0.0000015125073],"category_scores_gemma":[0.00031101273,0.00013833506,0.000014601657,0.0008537219,0.00011672098,0.000009252132,0.00017274813,0.000108617176,0.0000047309936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024408093,0.0000122823185,0.15507235,0.000028386741,0.0000019419797,0.00005395033,0.0005366671,0.00079080905,0.8399646,0.0000010799669,0.0024368477,0.0010766389],"study_design_scores_gemma":[0.0004259488,0.000085684536,0.12316888,0.00006699838,0.000002144971,0.000010309238,0.0009405767,0.007892226,0.8661014,0.000010019957,0.001055618,0.00024021463],"about_ca_topic_score_codex":0.00003742674,"about_ca_topic_score_gemma":0.0007769176,"teacher_disagreement_score":0.03190348,"about_ca_system_score_codex":0.00003263108,"about_ca_system_score_gemma":0.000057050343,"threshold_uncertainty_score":0.564114},"labels":[],"label_agreement":null},{"id":"W4386933946","doi":"10.1101/2023.09.20.558637","title":"The CASwitch: a synthetic biology solution for high-performance inducible gene expression systems in biotechnology","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Synthetic biology; Biology; Gene expression; Computational biology; Gene; CRISPR; Regulation of gene expression; Gene regulatory network; Cell biology; Genetics; Molecular biology","score_opus":0.015057980840516348,"score_gpt":0.2513662034085417,"score_spread":0.23630822256802536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386933946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94822514,0.005094309,0.042530432,0.00026197496,0.002504418,0.0010675594,0.00015101308,0.00016442186,7.5907894e-7],"genre_scores_gemma":[0.9932513,0.0026832554,0.0023503923,0.000018683897,0.00046443474,0.0010934832,0.000004304605,0.00012288328,0.000011217835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99760723,0.00008375937,0.0005188159,0.0009869154,0.0001213681,0.00068192143],"domain_scores_gemma":[0.9981217,0.000057711386,0.00023233636,0.0013377769,0.00016349702,0.00008698497],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007773472,0.00041547255,0.00038775124,0.00023237431,0.00020683013,0.00007520796,0.0006185447,0.001163404,7.387945e-7],"category_scores_gemma":[0.0002807467,0.0003710328,0.00008981045,0.00026930208,0.00012884416,0.0000048577085,0.000616001,0.00044415105,0.000011472902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000422385,0.000028653398,0.0007338495,0.00022302386,0.00005358447,0.0000030168035,0.0000024543776,0.0024031051,0.99616855,0.0001673363,0.00016073679,0.000013448417],"study_design_scores_gemma":[0.0004120475,0.00013819463,0.0044128634,0.00023380063,0.000028958602,7.1095926e-8,0.0000036989056,0.00349831,0.986762,0.0000038299618,0.0040561254,0.00045011842],"about_ca_topic_score_codex":0.000107922475,"about_ca_topic_score_gemma":0.000014910425,"teacher_disagreement_score":0.04502623,"about_ca_system_score_codex":0.00010200866,"about_ca_system_score_gemma":0.00023247788,"threshold_uncertainty_score":0.9998742},"labels":[],"label_agreement":null},{"id":"W4386944793","doi":"10.1007/s00277-023-05457-2","title":"CRISPR-Cas9 system: a novel and promising era of genotherapy for beta-hemoglobinopathies, hematological malignancy, and hemophilia","year":2023,"lang":"en","type":"review","venue":"Annals of Hematology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Chimeric antigen receptor; Genome editing; Cas9; Genetic enhancement; Hematology; Leukemia; Medicine; Immunotherapy; Cancer; Computational biology; Cancer research; Immunology; Bioinformatics; Biology; Gene; Internal medicine; Genetics","score_opus":0.08393311741432646,"score_gpt":0.3954667325821671,"score_spread":0.3115336151678406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386944793","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005949741,0.9901607,0.0024163614,0.00007547258,0.00011595193,0.0010073679,0.00022519125,0.000023672748,0.00002555463],"genre_scores_gemma":[0.009911323,0.9874318,0.0021758212,0.00003336125,0.000073914256,0.00016702508,0.00009883134,0.00007843587,0.000029485203],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978871,0.00006104095,0.000966106,0.0006011443,0.00010308261,0.0003815362],"domain_scores_gemma":[0.99877197,0.00013123488,0.00047868397,0.00040606706,0.00011768903,0.000094368006],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033177703,0.00042464092,0.002202162,0.00011754602,0.00005138827,0.000010427917,0.0002120371,0.0006497135,0.0000012093326],"category_scores_gemma":[0.00010921558,0.00036125747,0.00034656352,0.00012406161,0.00019713698,0.0000028664017,0.00017536063,0.0001540476,6.8750836e-7],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036740032,0.00052735384,0.00019325195,0.6063131,0.00385698,0.00010727865,0.0003841831,0.000014585923,0.041222304,0.02161752,0.0026503426,0.32274568],"study_design_scores_gemma":[0.0038788675,0.0036704533,0.00006798438,0.05794669,0.0024020171,0.011974053,0.00043983784,0.00018056075,0.3258898,0.00065168756,0.58970636,0.0031916942],"about_ca_topic_score_codex":0.0000074956956,"about_ca_topic_score_gemma":0.0000042280403,"teacher_disagreement_score":0.587056,"about_ca_system_score_codex":0.0000033304161,"about_ca_system_score_gemma":0.0001034501,"threshold_uncertainty_score":0.99988395},"labels":[],"label_agreement":null},{"id":"W4386947067","doi":"10.1016/j.ijfoodmicro.2023.110414","title":"Dairy phages escape CRISPR defence of Streptococcus thermophilus via the anti-CRISPR AcrIIA3","year":2023,"lang":"en","type":"article","venue":"International Journal of Food Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec; Université Laval","funders":"National Institutes of Health; Ian's Friends Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Streptococcus thermophilus; CRISPR; Virulence; Biology; Bacteria; Microbiology; Genetics; Gene; Lactobacillus","score_opus":0.008794769853939134,"score_gpt":0.29902310075604693,"score_spread":0.2902283309021078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386947067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98855424,0.0018814832,0.007329764,0.00066929904,0.0012945848,0.000092134156,0.00007018729,0.000007993637,0.0001002915],"genre_scores_gemma":[0.9985778,0.00052575767,0.0001748351,0.00015222008,0.00044473947,0.0000034075817,0.00004138187,0.00001582124,0.000064082684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999054,0.00006231619,0.0004234278,0.00016209559,0.00010545229,0.0001926939],"domain_scores_gemma":[0.9991127,0.00005241247,0.00026363033,0.00019527407,0.00033653105,0.000039437593],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028164886,0.00013644579,0.0001881405,0.0001237446,0.000033694523,0.000013569551,0.0006988226,0.00011298735,0.0000337304],"category_scores_gemma":[0.00010036976,0.00009907715,0.00019314516,0.00009884286,0.00012169084,0.0000059193467,0.00018102454,0.00015367735,0.000010289549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062003215,0.000037799655,0.00097108015,0.000007337955,0.00035572855,0.000015335081,0.000113427996,0.0011383496,0.99153125,0.00004014212,0.0025507968,0.0031767276],"study_design_scores_gemma":[0.00061241334,0.00050243846,0.005780642,0.00002804755,0.00003017157,0.00048350595,0.00016202657,0.000042604494,0.9801321,0.00016306383,0.011943208,0.00011975541],"about_ca_topic_score_codex":0.00000449432,"about_ca_topic_score_gemma":0.000009150882,"teacher_disagreement_score":0.011399149,"about_ca_system_score_codex":0.00001200388,"about_ca_system_score_gemma":0.000061741935,"threshold_uncertainty_score":0.4040249},"labels":[],"label_agreement":null},{"id":"W4387121752","doi":"10.1016/j.crbiot.2023.100147","title":"Strong expression of Cas9 under a new 3′-truncated TEF1α promoter enhances genome editing in Yarrowia lipolytica","year":2023,"lang":"en","type":"article","venue":"Current Research in Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Genome editing; Cas9; Genome; Yarrowia; Genetics; Gene; CRISPR; Promoter; Computational biology; Biology; Chemistry; Gene expression","score_opus":0.06456743369161637,"score_gpt":0.4249950085222469,"score_spread":0.36042757483063054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387121752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994287,0.0026848458,0.001538594,0.00083233864,0.00019707852,0.00032713308,0.000008278061,0.0000408699,0.00008383293],"genre_scores_gemma":[0.99828243,0.0010860328,0.00023897317,0.0000025441345,0.00015707826,0.000041353996,0.00006287946,0.00002004506,0.00010865237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828285,0.000077360484,0.00031571917,0.0004466988,0.00022508037,0.0006523148],"domain_scores_gemma":[0.9994131,0.000031566153,0.000042881045,0.00038675073,0.00005159407,0.000074154465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005930956,0.00013912281,0.00019128277,0.0007226287,0.000035655445,0.00001155494,0.00037545507,0.00035329687,0.000023133938],"category_scores_gemma":[0.00020171847,0.00013426691,0.000040648214,0.0009988693,0.00019005952,0.000004855631,0.00046563562,0.00055828516,0.00002078568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002342175,0.00005205238,0.0010364156,0.00007264681,0.0000056141757,0.000006942278,0.00006260365,0.0003187789,0.9882236,0.00013247562,0.00032821554,0.009737223],"study_design_scores_gemma":[0.0004540657,0.00019024598,0.0042765075,0.00016470141,0.0000015880221,0.000004255324,0.00026117061,0.00050665904,0.98758155,0.00041916274,0.0060047754,0.00013528937],"about_ca_topic_score_codex":0.00006138667,"about_ca_topic_score_gemma":0.00013782256,"teacher_disagreement_score":0.009601934,"about_ca_system_score_codex":0.000038942875,"about_ca_system_score_gemma":0.00013226998,"threshold_uncertainty_score":0.5475246},"labels":[],"label_agreement":null},{"id":"W4387190241","doi":"10.1016/j.cell.2023.08.031","title":"An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis","year":2023,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Genome editing; Genome; Gene; Computational biology; Human genome; Genetics; DNA","score_opus":0.0053480359353237925,"score_gpt":0.27437977408712405,"score_spread":0.26903173815180026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387190241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97377,0.00033320623,0.025633365,0.000025743702,0.000038404603,0.000049194656,0.00003704193,0.000024563285,0.00008845764],"genre_scores_gemma":[0.9973545,0.000007457708,0.000973812,0.00005287752,0.000104006205,0.0000029058308,0.0014344046,0.000013803892,0.00005619762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993932,0.000017632921,0.00010998185,0.00022433882,0.000079081,0.00017574022],"domain_scores_gemma":[0.99972415,0.000011765928,0.00003139183,0.0001331133,0.000028953693,0.00007063697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007222494,0.000100303725,0.00009872462,0.000068769674,0.00008087635,0.000037443995,0.000071562165,0.000053358617,0.000028177032],"category_scores_gemma":[0.000012522234,0.000105360254,0.000054367487,0.00018291666,0.000026413652,0.0000031144664,0.000018779896,0.00004278164,0.0000028555762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005618952,0.000004071813,0.007400332,0.000011911647,0.000051835057,0.0000027801032,0.00006468003,0.13474375,0.85726297,5.2939623e-7,0.000073055686,0.00037843376],"study_design_scores_gemma":[0.00050070795,0.00008808906,0.16413873,0.0000025720778,0.00011875109,0.0000035138055,0.0003057431,0.24555938,0.588488,0.000013407473,0.00051497406,0.00026612243],"about_ca_topic_score_codex":0.000011347871,"about_ca_topic_score_gemma":0.000011405928,"teacher_disagreement_score":0.268775,"about_ca_system_score_codex":0.000006469954,"about_ca_system_score_gemma":0.00001749457,"threshold_uncertainty_score":0.42964664},"labels":[],"label_agreement":null},{"id":"W4387220609","doi":"10.1101/2023.09.29.559947","title":"<i>In vivo</i> dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université Laval; Université de Montréal; Centre Hospitalier Universitaire de Sherbrooke; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Fondation du Grand défi Pierre Lavoie; Kidney Foundation of Canada; Canadian Institutes of Health Research; Canadian Society of Nephrology; Université Laval","keywords":"Tyrosinemia; Biology; Gene; Phenotype; Genetics; CRISPR; Genome editing; Gene knockin; Mutation; Tyrosine; Biochemistry","score_opus":0.009710644459998887,"score_gpt":0.24037713026500232,"score_spread":0.23066648580500343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387220609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99278706,0.0032309461,0.0014318232,0.000065591135,0.0016708508,0.00051857566,0.00021103879,0.00008040394,0.0000037284624],"genre_scores_gemma":[0.99794644,0.00055786246,0.00047210016,0.000043091048,0.0006494701,0.00008516454,0.000002373505,0.0001565635,0.00008693101],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802655,0.000083775194,0.00042351364,0.00076660025,0.0002820382,0.00041751898],"domain_scores_gemma":[0.99816775,0.000022551947,0.00024201267,0.0011824548,0.00029089733,0.00009435625],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033382745,0.00045053818,0.0003943359,0.00014411556,0.00010398695,0.00006541655,0.00045154986,0.00043161845,0.0000082700235],"category_scores_gemma":[0.00013708393,0.00038680417,0.00013427425,0.00050326675,0.000107583925,0.000012696324,0.0005129514,0.00041667465,0.000004984358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054333806,0.000056107,0.0069642025,0.00038471303,0.00008722219,0.000015415504,0.00001556922,0.0060867094,0.9855865,0.000011386756,0.0007367906,0.000001034602],"study_design_scores_gemma":[0.00031618294,0.000061596365,0.029303389,0.00022851475,0.000058399095,1.6726536e-7,0.000014215483,0.00018684463,0.96849245,6.745626e-7,0.0009019594,0.0004356206],"about_ca_topic_score_codex":0.00024902902,"about_ca_topic_score_gemma":0.0001446069,"teacher_disagreement_score":0.022339186,"about_ca_system_score_codex":0.000055979388,"about_ca_system_score_gemma":0.0002593839,"threshold_uncertainty_score":0.9998584},"labels":[],"label_agreement":null},{"id":"W4387251159","doi":"10.1109/cibcb56990.2023.10264893","title":"A Comparison of Machine Learning Models for Predicting CRISPR/Cas On-target Efficacy","year":2023,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"CRISPR; Computer science; Cas9; Artificial intelligence; Convolutional neural network; Deep learning; Machine learning; Guide RNA; Palindrome; Nuclease; Computational biology; Feature (linguistics); DNA; Biology; Genetics; Gene","score_opus":0.03296878057420358,"score_gpt":0.36159926095513534,"score_spread":0.3286304803809318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387251159","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.61615604,0.00039945557,0.3809992,0.00008577406,0.00013562209,0.0002659907,0.000025379042,0.00008586117,0.0018466664],"genre_scores_gemma":[0.9954803,0.000033797853,0.0032735947,0.000023305553,0.000106659354,0.000019962361,0.00017966553,0.000026842969,0.0008558444],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9992658,0.000013592076,0.00020302054,0.00021722514,0.00009160257,0.00020879143],"domain_scores_gemma":[0.9996461,0.000052130534,0.000045438206,0.00016466541,0.000043394164,0.00004825571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001560108,0.00011072887,0.00016030626,0.00005552202,0.00005872342,0.000007693917,0.000100919824,0.000077757984,0.000009515929],"category_scores_gemma":[0.0001319213,0.000104272214,0.00009340017,0.000093822695,0.0000148876325,0.0000013815711,0.000062339444,0.00007815267,0.000004188735],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008210908,0.000060146303,0.006693531,0.000060353028,0.00005329022,4.147124e-7,0.00023588394,0.7637653,0.22511624,0.00016882252,0.0016628824,0.002101078],"study_design_scores_gemma":[0.0004620703,0.00037445917,0.0006319141,0.000012060211,0.000010003091,7.778181e-7,0.00012870147,0.51163954,0.4822324,0.00005000611,0.004356413,0.000101678255],"about_ca_topic_score_codex":0.000011039621,"about_ca_topic_score_gemma":0.000006832294,"teacher_disagreement_score":0.3793243,"about_ca_system_score_codex":0.0000040342147,"about_ca_system_score_gemma":0.000013212734,"threshold_uncertainty_score":0.42520976},"labels":[],"label_agreement":null},{"id":"W4387300070","doi":"10.1371/journal.pone.0292180","title":"Establishing an online resource to facilitate global collaboration and inclusion of underrepresented populations: Experience from the MJFF Global Genetic Parkinson’s Disease Project","year":2023,"lang":"en","type":"review","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Occupational Cancer Research Centre; Toronto Western Hospital; University of Toronto","funders":"National Institutes of Health; H. Lundbeck A/S; Alzheimer Nederland; Deutsches Zentrum für Neurodegenerative Erkrankungen; National Institute for Health and Care Research; Bundesministerium für Bildung und Forschung; Cleveland Clinic; National Research Foundation; International Parkinson and Movement Disorder Society; Department of Science and Technology, Ministry of Science and Technology, India; Parkinson's Disease Foundation; NIHR Cambridge Biomedical Research Centre; U.S. Department of Defense; Sanofi; North-West University; Department of Health and Social Care; Michael J. Fox Foundation for Parkinson's Research","keywords":"Resource (disambiguation); Pace; Biorepository; Disease; Medicine; Clinical trial; White paper; Inclusion (mineral); Bioinformatics; Biobank; Psychology; Computer science; Political science; Geography; Biology; Pathology","score_opus":0.18419260251737998,"score_gpt":0.39437135957681896,"score_spread":0.21017875705943898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387300070","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19564366,0.7982141,0.0010630684,0.00008252367,0.000055600725,0.001203354,0.0036916772,0.000033167104,0.000012900624],"genre_scores_gemma":[0.023158735,0.9656582,0.0053232843,0.000074917196,0.00039177545,0.00022821483,0.005059364,0.00004820232,0.000057325582],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983064,0.00017607686,0.00042702473,0.00055691454,0.00034006275,0.00019350628],"domain_scores_gemma":[0.9989802,0.000037582053,0.00013542757,0.00061142835,0.000095751224,0.00013955774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012149519,0.00025127502,0.0004327157,0.00003214293,0.00020097337,0.00005910768,0.0003664286,0.00014430207,0.0000017176006],"category_scores_gemma":[0.00058084616,0.00020752229,0.000073687035,0.00051967055,0.00004818499,0.000007905403,0.0014919878,0.000077865145,0.0000010384208],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006517968,0.0030853618,0.018680714,0.017000578,0.00195206,0.00005351262,0.008070373,0.005152921,0.006217636,0.00006766002,0.0021414363,0.93692595],"study_design_scores_gemma":[0.0015203961,0.001105935,0.04155142,0.023985278,0.0042123217,0.00001302104,0.0043672808,0.0057453862,0.00053088926,0.0007840522,0.91342753,0.002756459],"about_ca_topic_score_codex":0.000593866,"about_ca_topic_score_gemma":0.0014089945,"teacher_disagreement_score":0.9341695,"about_ca_system_score_codex":0.00006305319,"about_ca_system_score_gemma":0.0001828995,"threshold_uncertainty_score":0.8462513},"labels":[],"label_agreement":null},{"id":"W4387306664","doi":"10.1016/j.nmd.2023.07.033","title":"P52 Experiences of parents/caregivers of children in the ASPIRO X-Linked myotubular myopathy (XLMTM) gene therapy clinical trial: a qualitative study","year":2023,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"MacEwan University; St. Michael's Hospital","funders":"","keywords":"Weakness; Medicine; Psychology; Clinical trial; Pediatrics; Internal medicine; Surgery","score_opus":0.03612833636376256,"score_gpt":0.39647257757926285,"score_spread":0.3603442412155003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387306664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975353,0.00083943736,0.00017870942,0.00008407645,0.00023769918,0.0010705712,0.00000911434,0.000014026424,0.00003110331],"genre_scores_gemma":[0.9982791,0.0013415725,0.00003183676,0.000057052777,0.000058806956,0.00014722013,0.000052962376,0.000024099212,0.0000073744345],"study_design_codex":"qualitative","study_design_gemma":"qualitative","domain_scores_codex":[0.99781346,0.0006828233,0.000534001,0.00042340436,0.00031944516,0.000226864],"domain_scores_gemma":[0.9991385,0.0000887059,0.00014151311,0.0005541301,0.000037367765,0.00003978039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010012338,0.00018518459,0.0003100993,0.00009267628,0.000040509192,0.000009831721,0.0004675936,0.00009932249,0.000008246585],"category_scores_gemma":[0.00020112503,0.00014498876,0.00027240653,0.00034254498,0.00016304964,0.0000035497433,0.00008869009,0.00012876534,0.0000020081902],"study_design_candidate":"qualitative","study_design_consensus":"qualitative","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010140378,0.006958239,0.09068846,0.00010640089,0.0014642779,0.000035997313,0.76490605,0.00642354,0.09256115,0.000039808816,0.0012920273,0.025383694],"study_design_scores_gemma":[0.048114683,0.012395553,0.2652821,0.000026764215,0.00011465351,0.0000031231875,0.653989,0.00014558352,0.017521644,0.00009985747,0.0015852551,0.0007217819],"about_ca_topic_score_codex":0.00008565143,"about_ca_topic_score_gemma":0.000038416492,"teacher_disagreement_score":0.17459363,"about_ca_system_score_codex":0.0000026379612,"about_ca_system_score_gemma":0.00003781961,"threshold_uncertainty_score":0.591247},"labels":[],"label_agreement":null},{"id":"W4387338477","doi":"10.1101/2023.10.03.560559","title":"CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CRISPR; Mitochondrial DNA; Genetics; Tandem; Biology; Computational biology; Evolutionary biology; Engineering; Gene","score_opus":0.013942377024132223,"score_gpt":0.26455972190793897,"score_spread":0.25061734488380677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387338477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9345291,0.0012594529,0.06237823,0.0001344512,0.00061760104,0.000689838,0.00014739318,0.00023293155,0.0000109529155],"genre_scores_gemma":[0.988849,0.00031814724,0.0097489925,0.00009865971,0.0005544351,0.0001736592,0.000007338185,0.00021733897,0.000032459026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968469,0.00014375384,0.0005938848,0.0013158809,0.00035872625,0.0007408342],"domain_scores_gemma":[0.99775,0.000026447866,0.00025800572,0.0014515952,0.00026455792,0.00024938228],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007819541,0.0006354027,0.0005903596,0.00025273714,0.00010669154,0.00014260197,0.00058564846,0.00070206216,0.00001775189],"category_scores_gemma":[0.00022353668,0.00068292266,0.00015841825,0.0004906497,0.00010284715,0.000009618318,0.0007049442,0.00071155385,0.000018072307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003998999,0.000065382716,0.06989404,0.00024993374,0.0001849682,0.00009553739,0.000007936376,0.0033620924,0.9255173,0.000025115705,0.0005561051,0.0000015599397],"study_design_scores_gemma":[0.000726198,0.00007682143,0.4384502,0.00041187194,0.00007708819,3.8020875e-8,0.000008481887,0.00053581205,0.55673945,0.0000017959294,0.0020553435,0.00091688184],"about_ca_topic_score_codex":0.000121686586,"about_ca_topic_score_gemma":0.00005106158,"teacher_disagreement_score":0.36877787,"about_ca_system_score_codex":0.00005837513,"about_ca_system_score_gemma":0.00028087304,"threshold_uncertainty_score":0.9995622},"labels":[],"label_agreement":null},{"id":"W4387341290","doi":"10.1038/s41467-023-41829-y","title":"PAM-flexible genome editing with an engineered chimeric Cas9","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Vallee Foundation; CHDI Foundation; Howard Hughes Medical Institute; National Heart, Lung, and Blood Institute; Krembil Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Cas9; Genome editing; CRISPR; Computational biology; Genome engineering; Genome; Limiting; Protein engineering; Biology; Translation (biology); Computer science; Genetics; Enzyme; Messenger RNA; Gene; Biochemistry","score_opus":0.012401899123779706,"score_gpt":0.32165405198305363,"score_spread":0.30925215285927393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387341290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9585448,0.014656944,0.012283238,0.0027311353,0.00048691538,0.00061694963,0.00013982771,0.0006496361,0.009890547],"genre_scores_gemma":[0.989781,0.00067437394,0.0078030126,0.000112404115,0.000217902,0.000040567065,0.0010602123,0.000030701227,0.0002798014],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994306,0.000026218075,0.00010119361,0.00017375851,0.00008104696,0.0001871998],"domain_scores_gemma":[0.99857616,0.000016936005,0.000027819824,0.001243156,0.00006672965,0.000069189584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107591724,0.00010731438,0.000079624086,0.00007454916,0.00014729713,0.00002145841,0.00052031083,0.00015731851,0.0000063363677],"category_scores_gemma":[0.000045176614,0.000101811005,0.000032842814,0.00037254996,0.000041558567,0.0000041471326,0.00018275755,0.00029773012,0.000015569147],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036678884,0.0001469093,0.0024590925,0.00004011031,0.00020366302,0.000007072563,0.0005312146,0.014437684,0.9705664,0.0013054239,0.0049633943,0.0053023584],"study_design_scores_gemma":[0.00092002674,0.0005132825,0.05945983,0.000035445428,0.00007843923,0.00009608508,0.0008367548,0.008142457,0.098146394,0.000060704955,0.83089316,0.00081740256],"about_ca_topic_score_codex":0.000008489193,"about_ca_topic_score_gemma":0.00012743454,"teacher_disagreement_score":0.87242,"about_ca_system_score_codex":0.000007761161,"about_ca_system_score_gemma":0.000029973759,"threshold_uncertainty_score":0.41517323},"labels":[],"label_agreement":null},{"id":"W4387346479","doi":"10.1145/3584371.3613007","title":"AcrTransAct: Pre-trained Protein Transformer Models for the Detection of Type I Anti-CRISPR Activities","year":2023,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Computational biology; Transformer; Computer science; Convolutional neural network; Palindrome; Artificial intelligence; Biology; Gene; Genetics; Engineering","score_opus":0.012509846586378253,"score_gpt":0.2892972792580063,"score_spread":0.27678743267162803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387346479","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4189659,0.00020317917,0.5801123,0.0000721554,0.000071022616,0.00038872682,0.00001275041,0.000022536633,0.00015142014],"genre_scores_gemma":[0.9980762,0.00016426099,0.00032291122,0.00001439282,0.00006103632,0.00008461586,0.000015592623,0.000017877124,0.0012431266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953264,0.00000701061,0.00011007112,0.00013107763,0.00006590529,0.00015326617],"domain_scores_gemma":[0.9997618,0.000016011005,0.000016378313,0.00014934133,0.000036748697,0.000019675499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011377454,0.000085422354,0.0000822767,0.000027830836,0.000049889986,0.0000073122437,0.00008382364,0.000073747644,0.0000067099086],"category_scores_gemma":[0.000011423727,0.000061538165,0.00008133957,0.00010297106,0.000027861313,0.0000035590404,0.0000062825925,0.000035265337,7.129397e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000073310715,0.0000097177,0.0000032055307,0.00005386621,0.000043236396,6.314485e-8,0.0001268267,0.013085166,0.97770053,0.000039229348,0.00004693345,0.008817923],"study_design_scores_gemma":[0.00025741832,0.00018535652,0.00019886119,0.0000061273367,0.000018246468,0.000001195771,0.00019132494,0.024489257,0.9721637,0.00010173434,0.002302442,0.00008437754],"about_ca_topic_score_codex":0.000017308335,"about_ca_topic_score_gemma":0.000043321248,"teacher_disagreement_score":0.5797894,"about_ca_system_score_codex":0.0000025151842,"about_ca_system_score_gemma":0.000020476593,"threshold_uncertainty_score":0.25094536},"labels":[],"label_agreement":null},{"id":"W4387358716","doi":"10.1016/j.focha.2023.100476","title":"Understanding the emerging potential of synthetic biology for food science: Achievements, applications and safety considerations","year":2023,"lang":"en","type":"article","venue":"Food Chemistry Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"Consórcio Pesquisa Café; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Canada Research Chairs; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation","keywords":"Synthetic biology; Biosecurity; Biosafety; Toolbox; Biotechnology; Risk analysis (engineering); Engineering ethics; Biochemical engineering; Nanotechnology; Computer science; Business; Biology; Engineering; Computational biology; Ecology","score_opus":0.021614542788667403,"score_gpt":0.3130977460364281,"score_spread":0.29148320324776067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387358716","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4149591,0.0036074216,0.5785166,0.000715816,0.00017005553,0.00062848756,0.0003822419,0.00004663636,0.0009736593],"genre_scores_gemma":[0.998698,0.00037146066,0.0006519604,0.000014247281,0.00008336783,0.00008715323,0.00005453323,0.000008018244,0.000031266904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939066,0.000005344313,0.00014438288,0.00022459948,0.00006241452,0.00017258347],"domain_scores_gemma":[0.9996527,0.000038791837,0.00005174506,0.00017786742,0.000045069668,0.00003384204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015508528,0.0000800565,0.00007665295,0.000022241678,0.00030149505,0.000014154709,0.000108556414,0.00004069082,0.0000043494183],"category_scores_gemma":[0.00007280891,0.00006857711,0.000035367902,0.00013689835,0.00027713543,0.0000044457515,0.00007969105,0.000036005822,1.9562488e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008763044,0.000008185958,0.00006899507,0.00006566163,0.00003123524,3.551393e-8,0.000030391127,0.0023530782,0.9951134,0.00173862,0.00002636282,0.000555279],"study_design_scores_gemma":[0.00028712125,0.00013094244,0.00006606223,0.000010883295,0.000024552406,0.0000076235565,0.0010442543,0.00048948755,0.98147345,0.008766287,0.0075844903,0.00011487774],"about_ca_topic_score_codex":1.577104e-7,"about_ca_topic_score_gemma":0.000002389436,"teacher_disagreement_score":0.5837389,"about_ca_system_score_codex":0.000009306267,"about_ca_system_score_gemma":0.000042222942,"threshold_uncertainty_score":0.27964932},"labels":[],"label_agreement":null},{"id":"W4387362764","doi":"10.7554/elife.91288","title":"Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Université de Montréal; Terry Fox Research Institute; Fonds de Recherche du Québec - Santé; Sleep Research Society Foundation; Cancer Research Society","keywords":"Stem cell; Haematopoiesis; Progenitor cell; Cell biology; Biology; Genome editing; Developmental biology; Progenitor; Computational biology; Genetics; CRISPR; Gene","score_opus":0.00991348854878268,"score_gpt":0.28875705067809393,"score_spread":0.2788435621293113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387362764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99883443,0.0003861746,0.00016225307,0.000021507323,0.00017300522,0.00013129356,0.000012355568,0.000026368712,0.00025259785],"genre_scores_gemma":[0.9989172,0.000038820323,0.00025703933,0.000021087311,0.00032782502,0.000015355496,0.000020996727,0.000021321606,0.00038031908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936473,0.000015977717,0.00014390923,0.00019532151,0.00011484936,0.00016521187],"domain_scores_gemma":[0.999677,0.00001199726,0.000034346584,0.0001863897,0.000029709836,0.000060538994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013455952,0.000098503515,0.000114252514,0.000027289714,0.000057499794,0.000013950402,0.00007415661,0.00006661056,0.0000070870706],"category_scores_gemma":[0.000017958006,0.000095958305,0.00004489336,0.00007151723,0.00003467026,0.00000114223,0.00006906286,0.000050264287,0.000014288969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007774523,0.000017231181,0.0018827394,0.00008381117,0.000022142738,0.000002871289,0.00016651706,0.0006499632,0.99381816,0.000010940992,0.0028663357,0.0004715062],"study_design_scores_gemma":[0.00020187774,0.00019383033,0.0009292737,0.000027293509,0.000007327084,0.0000031885795,0.00010588476,0.0003258598,0.9947573,0.000004389683,0.003346073,0.000097695796],"about_ca_topic_score_codex":0.000002273291,"about_ca_topic_score_gemma":0.0000012776114,"teacher_disagreement_score":0.00095346564,"about_ca_system_score_codex":0.0000029296207,"about_ca_system_score_gemma":0.000014993018,"threshold_uncertainty_score":0.39130664},"labels":[],"label_agreement":null},{"id":"W4387362838","doi":"10.7554/elife.91288.1","title":"Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells","year":2023,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Université de Montréal; Fonds de Recherche du Québec - Santé; Sleep Research Society Foundation; Cancer Research Society","keywords":"Genome editing; Progenitor cell; Stem cell; Biology; Computational biology; Haematopoiesis; CRISPR; Primary cell; Cord blood; Genetics; Computer science; Gene","score_opus":0.01675958343028118,"score_gpt":0.3024296344974294,"score_spread":0.2856700510671482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387362838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955059,0.000697411,0.0019630676,0.000033406814,0.0006259361,0.00046223696,0.000056358225,0.000051389,0.0006042589],"genre_scores_gemma":[0.9957922,0.000080706384,0.0017518963,0.000013553695,0.00054860604,0.000060807877,0.00009542756,0.00006666154,0.001590143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987126,0.00003091206,0.00032184337,0.00053836347,0.00015683712,0.00023945037],"domain_scores_gemma":[0.9992207,0.000019517105,0.000105871164,0.00050276564,0.000060018978,0.00009107032],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019157439,0.00027259075,0.00030877523,0.000049455033,0.000058756432,0.000042309468,0.00019713794,0.00031146125,0.000016065977],"category_scores_gemma":[0.000019171297,0.0002629147,0.00013377973,0.00004177965,0.000063425214,8.1277346e-7,0.00055694534,0.00021105063,0.000008012239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022188948,0.00007010648,0.0016997556,0.0012978918,0.00018397988,0.0000074616833,0.0002658991,0.0069486434,0.98529965,0.00003265661,0.0034465352,0.0007252586],"study_design_scores_gemma":[0.00021060716,0.0002326486,0.0002907249,0.00015966051,0.00003360016,0.0000042754928,0.00011350015,0.0005891026,0.99730545,0.00007287912,0.00071534474,0.00027221418],"about_ca_topic_score_codex":0.000018558554,"about_ca_topic_score_gemma":0.0000081985,"teacher_disagreement_score":0.01200582,"about_ca_system_score_codex":0.000008377046,"about_ca_system_score_gemma":0.00004812475,"threshold_uncertainty_score":0.9999823},"labels":[],"label_agreement":null},{"id":"W4387378177","doi":"10.1016/j.ajhg.2023.09.004","title":"Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction","year":2023,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Vetenskapsrådet; York University; Simons Foundation Autism Research Initiative; University of Iowa; Aldeyra Therapeutics; National Human Genome Research Institute; New York University; Simons Foundation","keywords":"Biology; Chromatin; Genetics; Exome sequencing; Chromodomain; Neuroscience; Gene; Mutation","score_opus":0.01180728399286157,"score_gpt":0.2854013669779162,"score_spread":0.2735940829850546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387378177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997174,0.0009874782,0.0013493814,0.00017978584,0.00016797456,0.000121035366,0.000006071479,0.000007575126,0.0000066473267],"genre_scores_gemma":[0.9984901,0.0010203747,0.00027945664,0.000058474696,0.00010059226,0.0000039255888,0.000010331632,0.000021305552,0.000015416692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999029,0.00015457236,0.0003177112,0.00012660431,0.00018661794,0.00018553881],"domain_scores_gemma":[0.99918306,0.000029953027,0.00045977044,0.00023102546,0.00005960316,0.000036565205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032568857,0.00013068852,0.00022314489,0.000071934606,0.00009922081,0.0000136159,0.00018585178,0.000050809467,0.0000029296418],"category_scores_gemma":[0.00003893335,0.000089561196,0.000076112236,0.00023953222,0.00017509543,0.0000043698537,0.0000930791,0.00013388613,4.987721e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005640095,0.000026750366,0.0033622193,0.000010371696,0.00006325128,0.0000017025217,0.00041011014,0.008014017,0.98647344,0.0000014529086,0.00011651983,0.0014637677],"study_design_scores_gemma":[0.000513047,0.0014899141,0.2594655,0.00008608208,0.000068384965,0.00007648491,0.00051814574,0.0007671476,0.736675,0.00014977719,0.00006622389,0.00012428811],"about_ca_topic_score_codex":0.000030658182,"about_ca_topic_score_gemma":0.000059216167,"teacher_disagreement_score":0.25610325,"about_ca_system_score_codex":0.000028192017,"about_ca_system_score_gemma":0.000023780078,"threshold_uncertainty_score":0.36521995},"labels":[],"label_agreement":null},{"id":"W4387389398","doi":"10.1186/s13104-023-06533-6","title":"Expansions to the MGDrivE suite for simulating the efficacy of novel gene-drive constructs in the control of mosquito-borne diseases","year":2023,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Future Earth","funders":"College of Agriculture and Life Sciences, Texas A and M University","keywords":"Suite; Gene drive; Control (management); Computational biology; Biology; Computer science; Gene; Medicine; Genetics; Artificial intelligence; Geography; CRISPR","score_opus":0.07615589771255377,"score_gpt":0.4284694686612981,"score_spread":0.3523135709487443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387389398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9725246,0.00046981653,0.024497641,0.0010460586,0.00005112955,0.0011541961,0.00023552871,0.000005507223,0.000015528609],"genre_scores_gemma":[0.99896073,0.00003810702,0.0005675213,0.00004787965,0.00017195694,0.00014512753,0.000032939573,0.000014107993,0.000021601461],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882025,0.00014662115,0.00021771586,0.00020897547,0.00028613603,0.00032031286],"domain_scores_gemma":[0.9957862,0.0034227578,0.000039892147,0.00049045775,0.00021482055,0.00004589829],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094447134,0.00009038034,0.00013260999,0.00007197925,0.00013650571,0.000020342673,0.0004730294,0.00004786292,0.0000019467373],"category_scores_gemma":[0.005168956,0.00004851807,0.00009787742,0.0004162458,0.00019221503,0.0000020051798,0.00017688771,0.00010191376,0.0000013492297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013988244,0.000059605878,0.0064107683,0.000050283124,0.000034516528,5.881228e-7,0.0007563162,0.15782261,0.8325334,0.00038962852,0.0003305671,0.0014717992],"study_design_scores_gemma":[0.003714467,0.00070021255,0.24049765,0.0001215115,0.000058389378,0.0000042728593,0.0048204325,0.07021813,0.6768949,0.00019120776,0.002524115,0.00025468518],"about_ca_topic_score_codex":0.00005486419,"about_ca_topic_score_gemma":0.0001679606,"teacher_disagreement_score":0.23408689,"about_ca_system_score_codex":0.0000055024984,"about_ca_system_score_gemma":0.0001063002,"threshold_uncertainty_score":0.6188096},"labels":[],"label_agreement":null},{"id":"W4387473048","doi":"10.2144/btn-2023-0042","title":"Playback Cloning: Simple, Reversible, Cost-effective Cloning for the Combinatorial Assembly of Complex Expression Constructs","year":2023,"lang":"en","type":"article","venue":"BioTechniques","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cloning (programming); Computer science; Computational biology; Plasmid; Construct (python library); Usability; Multiple cloning site; Cloning vector; Biology; Expression vector; Recombinant DNA; Vector (molecular biology); Genetics; DNA; Programming language; Human–computer interaction; Gene","score_opus":0.022571710788144565,"score_gpt":0.3474505850405466,"score_spread":0.32487887425240203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387473048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7361723,0.0008596679,0.25528643,0.00026091916,0.00096869224,0.0050665597,0.00024062656,0.00034117678,0.00080363336],"genre_scores_gemma":[0.9944281,0.00020292343,0.004625347,0.000038569055,0.00021194875,0.00026134553,0.00015827271,0.000026737393,0.00004675111],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918205,0.0000389661,0.00019396281,0.00024597123,0.00010873924,0.00023032488],"domain_scores_gemma":[0.99932367,0.00014369476,0.00009065676,0.00029896552,0.00010084741,0.000042145362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003052171,0.00014572914,0.00017159444,0.000055968587,0.000121079065,0.000017432536,0.00021413383,0.00020906069,0.0000044422422],"category_scores_gemma":[0.00017835163,0.00011835905,0.000108462635,0.00016063587,0.00008800792,0.0000033759502,0.00015871818,0.00009211501,0.000001214658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008649155,0.000011880997,0.00019054783,0.00004631724,0.00003293366,6.758124e-7,0.00003442963,0.00011958496,0.9794469,0.00037270098,0.016233914,0.0034236612],"study_design_scores_gemma":[0.00044136558,0.0002736547,0.0012201816,0.0000385222,0.000018955074,0.0000036377107,0.00007281053,0.0005861294,0.9269329,0.00018216483,0.07009168,0.0001380497],"about_ca_topic_score_codex":0.00001891448,"about_ca_topic_score_gemma":0.0000035934866,"teacher_disagreement_score":0.2582558,"about_ca_system_score_codex":0.000012807132,"about_ca_system_score_gemma":0.0000331889,"threshold_uncertainty_score":0.4826542},"labels":[],"label_agreement":null},{"id":"W4387515915","doi":"10.1101/pdb.prot108340","title":"Validating Single-Guide RNA for<i>Aedes aegypti</i>Gene Editing","year":2023,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Aedes aegypti; Computational biology; RNA editing; Gene; Biology; RNA; Computer science; Genetics; Ecology; Larva","score_opus":0.02819755587767136,"score_gpt":0.33956599306433316,"score_spread":0.3113684371866618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387515915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62029076,0.00043488454,0.2677322,0.0004492287,0.0011647033,0.10586641,0.00012248491,0.0011006949,0.0028386596],"genre_scores_gemma":[0.87385654,0.000013145781,0.026029574,0.00017505299,0.002746238,0.09589855,0.000030287272,0.00017929752,0.001071298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998473,0.000023966564,0.0003473008,0.00046640297,0.00016764445,0.00052167237],"domain_scores_gemma":[0.99919367,0.00004008411,0.00010011877,0.00044445106,0.000108483604,0.00011322297],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048431815,0.00022119322,0.00019321407,0.000077153185,0.00017231752,0.00009908469,0.00027568697,0.00013545025,0.0000064315723],"category_scores_gemma":[0.00040380686,0.0002473275,0.0001406852,0.00019138132,0.00003057133,0.0000065440713,0.00019489533,0.00009518117,0.000019701676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018011024,0.000022755536,0.0005551476,0.00014072085,0.00003118804,0.000003841576,0.00001483893,0.0013124897,0.9953337,0.00028686208,0.0014759216,0.0008045802],"study_design_scores_gemma":[0.0005852644,0.00017049618,0.0005043803,0.000103571845,0.000010554868,8.6008794e-7,0.000016883105,0.0009393047,0.84808224,0.000012158864,0.14932534,0.00024896534],"about_ca_topic_score_codex":0.000006906672,"about_ca_topic_score_gemma":0.000004377635,"teacher_disagreement_score":0.25356582,"about_ca_system_score_codex":0.000030059202,"about_ca_system_score_gemma":0.00005174645,"threshold_uncertainty_score":0.9999979},"labels":[],"label_agreement":null},{"id":"W4387516098","doi":"10.1101/pdb.top107688","title":"Design and Validation of Guide RNAs for CRISPR–Cas9 Genome Editing in Mosquitoes","year":2023,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Genome editing; Cas9; Guide RNA; Computational biology; Biology; Flexibility (engineering); Software deployment; Population; Gene; Computer science; Genetics; Software engineering; Medicine","score_opus":0.025195650491281536,"score_gpt":0.3423804933421006,"score_spread":0.31718484285081905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387516098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5707667,0.00020653087,0.3763328,0.00008908933,0.000111219146,0.052350447,0.000015890779,0.000067025656,0.00006031806],"genre_scores_gemma":[0.9298171,0.00002715279,0.017820455,0.000021598667,0.0002934001,0.05186584,0.0000065499657,0.00004502951,0.000102867445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992287,0.000022524819,0.00024035301,0.00022983631,0.000073963165,0.00020460319],"domain_scores_gemma":[0.9996289,0.000032076365,0.00006092113,0.00018470858,0.00005487827,0.000038502512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004907675,0.000100412515,0.00012798708,0.00007546037,0.000034421908,0.000020834543,0.000102702026,0.00007732276,0.0000016987999],"category_scores_gemma":[0.00017098396,0.00011074333,0.000033350905,0.00010995838,0.000019453,0.0000042611014,0.0000768054,0.000040808005,0.0000011421253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026878644,0.000011922618,0.0009791846,0.00018452657,0.000010261164,0.0000011577466,0.000027425518,0.0081487335,0.9901944,0.00013101229,0.000097234755,0.0001872663],"study_design_scores_gemma":[0.0005781037,0.00015711394,0.006784572,0.000075536256,0.000005275231,2.9584666e-7,0.00001591846,0.0025033262,0.9744231,0.00001862219,0.015319402,0.00011875226],"about_ca_topic_score_codex":0.0000067921583,"about_ca_topic_score_gemma":0.0000017218531,"teacher_disagreement_score":0.35905042,"about_ca_system_score_codex":0.000011005036,"about_ca_system_score_gemma":0.000033025743,"threshold_uncertainty_score":0.45159817},"labels":[],"label_agreement":null},{"id":"W4387520079","doi":"10.1101/2023.10.10.561637","title":"Overriding Mendelian inheritance in <i>Arabidopsis</i> with a CRISPR toxin-antidote gene drive that impairs pollen germination","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Chinese Academy of Sciences","keywords":"Biology; Gene drive; CRISPR; Mendelian inheritance; Genetics; Gene; Pollen; Arabidopsis; Botany; Mutant","score_opus":0.01251862946017612,"score_gpt":0.2519083071375836,"score_spread":0.2393896776774075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387520079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849728,0.0019281363,0.010901135,0.00022782541,0.0007510036,0.0007366264,0.00027008416,0.00019709612,0.000015334917],"genre_scores_gemma":[0.9924091,0.0011150705,0.0053977654,0.00012768655,0.00043916595,0.000246512,0.000005356645,0.00022857227,0.00003075331],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970591,0.000086708234,0.00046925867,0.0012805596,0.00038917278,0.00071521354],"domain_scores_gemma":[0.9981187,0.000021869551,0.00027257056,0.0011493184,0.00022247914,0.00021507023],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048582663,0.00065062067,0.0005258939,0.00031597965,0.00010457597,0.00013254456,0.00051067764,0.0006118627,0.000008133485],"category_scores_gemma":[0.00010271283,0.00070338097,0.00015629137,0.00047835568,0.000080413185,0.000016890892,0.0005076499,0.0005406074,0.00001980627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062212086,0.000061005096,0.015351918,0.00022082627,0.00014675775,0.00008781605,0.000021587948,0.0031498394,0.9804109,0.00001859074,0.0004650865,0.0000034769275],"study_design_scores_gemma":[0.00073057204,0.000109852794,0.085278235,0.0003935949,0.00006628824,1.4956663e-7,0.000018872573,0.0007167175,0.9098914,0.0000015996587,0.0019056925,0.00088698824],"about_ca_topic_score_codex":0.000097291464,"about_ca_topic_score_gemma":0.00007392299,"teacher_disagreement_score":0.07051945,"about_ca_system_score_codex":0.00018089479,"about_ca_system_score_gemma":0.00038004096,"threshold_uncertainty_score":0.99954176},"labels":[],"label_agreement":null},{"id":"W4387817688","doi":"10.21769/bioprotoc.4846","title":"Doxycycline-inducible Expression of Proteins at Near-endogenous Levels in Mammalian Cells Using the Sleeping Beauty Transposon System","year":2023,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Canadian Institutes of Health Research","keywords":"Gene knockdown; Gene silencing; Mutant; Fusion protein; Cell biology; Green fluorescent protein; Ectopic expression; Biology; Target protein; Protein subcellular localization prediction; Expression vector; Genetic screen; Transfection; Gene; Genetics; Recombinant DNA","score_opus":0.04840558977382723,"score_gpt":0.33393736246720435,"score_spread":0.2855317726933771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387817688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77466244,0.000024478217,0.00291112,0.000027271753,0.00011584046,0.22198161,0.000043393848,0.00004866941,0.00018519048],"genre_scores_gemma":[0.81022906,7.699481e-7,0.0011095376,0.000009367002,0.0001309306,0.18839256,0.000011810396,0.000036928595,0.000079019395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998575,0.00008356661,0.0004021354,0.00036612255,0.000185653,0.0003875679],"domain_scores_gemma":[0.9992742,0.000012766952,0.00011213699,0.00049542397,0.000037760117,0.00006773402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003970913,0.00019646331,0.00020148265,0.00006425208,0.00014221422,0.000020426745,0.00026111212,0.00018606684,0.000013521401],"category_scores_gemma":[0.000016051205,0.00015406868,0.000112506365,0.00030101792,0.000051696108,0.000004283904,0.00012923016,0.00010425297,0.000008227077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092097776,0.000029747689,0.0008998355,0.00050609076,0.000009268496,0.000011809517,0.00021357066,0.0076033627,0.99017763,0.0000029547034,0.00004126511,0.0004123362],"study_design_scores_gemma":[0.0009763411,0.00012658803,0.0016824864,0.00022561847,0.000007843511,0.000013658833,0.00015260496,0.0018951915,0.9888053,0.0000020514253,0.005927817,0.00018453275],"about_ca_topic_score_codex":0.0001284299,"about_ca_topic_score_gemma":0.000052009847,"teacher_disagreement_score":0.03556664,"about_ca_system_score_codex":0.000050007384,"about_ca_system_score_gemma":0.000068683075,"threshold_uncertainty_score":0.62827384},"labels":[],"label_agreement":null},{"id":"W4387823228","doi":"10.1101/2023.10.19.562811","title":"Sub-retinal transplantation of human iPSC-derived retinal sheets: A promising approach for the treatment of macular degeneration","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Health Canada; Bausch Health; Stem Cell Network","keywords":"Induced pluripotent stem cell; Retinal; Retina; Transplantation; Biology; Macular degeneration; Neuroscience; Retinal regeneration; Retinal degeneration; Progenitor cell; Cell biology; Stem cell; Embryonic stem cell; Ophthalmology; Medicine; Genetics; Internal medicine; Biochemistry","score_opus":0.019448179177472148,"score_gpt":0.2673057643892851,"score_spread":0.24785758521181295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387823228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8568425,0.0014226141,0.14026324,0.00002322756,0.00018053387,0.0010216235,0.00021134799,0.000033277174,0.0000016044618],"genre_scores_gemma":[0.98868,0.0012268089,0.009197692,0.000005882796,0.00034784526,0.00043121885,0.000023503857,0.000083617306,0.0000034063771],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984849,0.000060001854,0.00046816547,0.0005499148,0.00018501129,0.00025202034],"domain_scores_gemma":[0.99875766,0.000024219966,0.00028042527,0.0006118777,0.0002655586,0.000060230665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031449943,0.00032470495,0.00034732526,0.00009076442,0.00011273451,0.000034005854,0.00023226827,0.00030184037,0.000002069346],"category_scores_gemma":[0.00003293674,0.00028886765,0.00023438272,0.00011989898,0.000086244916,0.0000036617869,0.000047996244,0.000101825484,3.6603456e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109773304,0.00012617707,0.00067654636,0.0006994337,0.00020826553,0.0000018326658,0.000041437936,0.005666634,0.9924072,0.000036868718,0.000018066225,0.000007763051],"study_design_scores_gemma":[0.000729656,0.00040457852,0.012817641,0.00010850334,0.0003129956,4.272078e-8,0.0000096018275,0.0030040133,0.982234,6.6494533e-7,0.00010422321,0.00027405412],"about_ca_topic_score_codex":0.000033510147,"about_ca_topic_score_gemma":0.0000057225857,"teacher_disagreement_score":0.1318375,"about_ca_system_score_codex":0.000047619673,"about_ca_system_score_gemma":0.00014521257,"threshold_uncertainty_score":0.99995637},"labels":[],"label_agreement":null},{"id":"W4387880240","doi":"10.1021/acssuschemeng.3c05735","title":"CRISPR Tools in Bacterial Whole-Cell Biocatalysis","year":2023,"lang":"en","type":"article","venue":"ACS Sustainable Chemistry & Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Agencia Nacional de Investigación e Innovación; Programa de Desarrollo de las Ciencias Básicas","keywords":"CRISPR; Biochemical engineering; Biocatalysis; Biotechnology; Metabolic engineering; Synthetic biology; Industrial biotechnology; Nanotechnology; Computational biology; Biology; Engineering; Materials science; Genetics; Catalysis","score_opus":0.00563463064542693,"score_gpt":0.24703286467319707,"score_spread":0.24139823402777014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387880240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99603194,0.0004962948,0.0019862184,0.00008668127,0.00011612612,0.00015056903,0.00001580299,0.00012588706,0.0009904819],"genre_scores_gemma":[0.9912535,0.00012425894,0.000297465,0.000013969571,0.00029962612,0.000078239595,0.0005791915,0.00006776845,0.007285983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983622,0.0000070716933,0.00027902445,0.00045490806,0.00013851591,0.0007583103],"domain_scores_gemma":[0.99926656,0.000021788348,0.000035724843,0.00048295635,0.00006919139,0.00012377642],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021567267,0.00027509464,0.00021708869,0.000106719104,0.000050083858,0.000080651895,0.0002983509,0.00021992292,0.00003375207],"category_scores_gemma":[0.00023252111,0.00033105077,0.00009771928,0.00058776734,0.000020684205,0.000014451451,0.0002722226,0.00017223017,0.000025462698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013285505,0.000021452539,0.00018139397,0.00032513938,0.000021346817,0.00007336581,0.000059641392,0.053956248,0.9440889,0.000008491345,0.001091182,0.00015959544],"study_design_scores_gemma":[0.00050486415,0.000020757087,0.00057616574,0.000017905717,0.000013270844,0.0000097862,0.0005602492,0.0010527583,0.9084748,0.0000063083976,0.08840237,0.00036077833],"about_ca_topic_score_codex":0.000018845742,"about_ca_topic_score_gemma":8.7824617e-7,"teacher_disagreement_score":0.087311186,"about_ca_system_score_codex":0.000065015374,"about_ca_system_score_gemma":0.000070613794,"threshold_uncertainty_score":0.99991417},"labels":[],"label_agreement":null},{"id":"W4387965927","doi":"10.1111/1755-0998.13881","title":"CRISPR‐based diagnostics detects invasive insect pests","year":2023,"lang":"en","type":"article","venue":"Molecular Ecology Resources","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Agriculture and Agri-Food Canada; Animal and Plant Health Inspection Service; Indian Agricultural Research Institute; National Institutes of Health; Indian Council of Agricultural Research; U.S. Department of Agriculture","keywords":"Biology; CRISPR; Computational biology; Identification (biology); Molecular diagnostics; Biotechnology; Gene; Genetics; Ecology","score_opus":0.00859471678461473,"score_gpt":0.2688894441509841,"score_spread":0.2602947273663694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387965927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945611,0.0009141827,0.0031191446,0.00030452033,0.00024084309,0.00022828951,0.000013678953,0.000104955085,0.00051331555],"genre_scores_gemma":[0.9979002,0.00020489689,0.00039091168,0.0008827869,0.00013962902,0.00008839553,0.00012587204,0.00005509171,0.00021225079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861026,0.00009898342,0.0002074769,0.0004566555,0.00014148928,0.000485109],"domain_scores_gemma":[0.99919444,0.00011679762,0.00005738911,0.00043404428,0.00006551447,0.00013178616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001738803,0.00022814846,0.00019916998,0.00016661141,0.00011226747,0.000028020835,0.00028959746,0.00027206598,0.000028504013],"category_scores_gemma":[0.00076971954,0.00024423513,0.0001297816,0.0002906166,0.00010367185,0.0000017346526,0.00019052539,0.00013993634,0.00011600099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050687326,0.000058826125,0.030558944,0.00006656497,0.00011431025,0.00039900703,0.00015170373,0.018118346,0.9431318,0.000021080194,0.006386406,0.00094232406],"study_design_scores_gemma":[0.000764645,0.00054410036,0.07089303,0.000017719161,0.00004658793,0.000029843284,0.000087891254,0.00067793234,0.8926115,0.00008416015,0.033838905,0.0004036873],"about_ca_topic_score_codex":0.000009406198,"about_ca_topic_score_gemma":0.00020268021,"teacher_disagreement_score":0.050520305,"about_ca_system_score_codex":0.0000140421025,"about_ca_system_score_gemma":0.00007446104,"threshold_uncertainty_score":0.9959619},"labels":[],"label_agreement":null},{"id":"W4388011859","doi":"10.1016/j.omtn.2023.102066","title":"Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi","year":2023,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"European Regional Development Fund; Novo Nordisk Fonden; Consejería de Salud y Consumo, Junta de Andalucía; Junta de Andalucía; Lundbeckfonden; Consejería de Transformación Económica, Industria, Conocimiento y Universidades; Consejería de Salud y Familias, Junta de Andalucía; Steno Diabetes Center Aarhus; European Cooperation in Science and Technology","keywords":"Harmonization; Genome editing; Action (physics); Business; Engineering ethics; Knowledge management; Political science; Biotechnology; Genome; Computer science; Gene; Biology; Engineering; Genetics","score_opus":0.03568538218232281,"score_gpt":0.3714595403355327,"score_spread":0.3357741581532099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388011859","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06766096,0.92315364,0.007451358,0.000011000939,0.00014448285,0.0013793502,0.0001351125,0.000039698418,0.000024427818],"genre_scores_gemma":[0.034679282,0.96237934,0.0010073078,0.000019556852,0.00043539063,0.00026320247,0.0009283815,0.00020935066,0.00007820557],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998475,0.000050120278,0.0005040672,0.0005006674,0.00020991912,0.0002602311],"domain_scores_gemma":[0.9991339,0.0000076637025,0.00027111592,0.0003451743,0.00012080956,0.000121350124],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012565496,0.00037468295,0.0006969202,0.00018514924,0.00007124954,0.000030906394,0.00023063949,0.00021581443,0.000005739559],"category_scores_gemma":[0.000027920696,0.00036084323,0.00023975057,0.0003205497,0.00007190815,0.000005068929,0.0001072091,0.000102920305,0.0000018049527],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024600478,0.00007665081,0.00024480335,0.005728736,0.00037822037,0.0000088946845,0.00011410673,0.00009283271,0.4196294,0.000016302873,0.00008345502,0.57360196],"study_design_scores_gemma":[0.0011212467,0.0008122122,0.0002382127,0.0033198441,0.00085864065,0.000046919373,0.00015602892,0.00006329292,0.8581981,0.000022047521,0.13413711,0.0010263253],"about_ca_topic_score_codex":0.000007775696,"about_ca_topic_score_gemma":0.000001034505,"teacher_disagreement_score":0.5725757,"about_ca_system_score_codex":0.000026327918,"about_ca_system_score_gemma":0.000059484264,"threshold_uncertainty_score":0.99988437},"labels":[],"label_agreement":null},{"id":"W4388073164","doi":"10.3390/ijms242115835","title":"Analysis of Potential Gene Doping Preparations for Transgenic DNA in the Context of Sports Drug Testing Programs","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Context (archaeology); Transgene; Gene; Polymerase chain reaction; Promoter; Complementary DNA; Primer (cosmetics); Real-time polymerase chain reaction; Molecular biology; Computational biology; Biology; Chemistry; Genetics; Gene expression","score_opus":0.018048935278220754,"score_gpt":0.33594909863230327,"score_spread":0.3179001633540825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388073164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.971587,0.0002999033,0.027703365,0.00016768463,0.0001237087,0.000081306825,0.0000078038765,0.0000012685138,0.000027929635],"genre_scores_gemma":[0.997696,0.00004635922,0.0021679094,0.00002406905,0.000040351613,0.0000041765065,0.000013752559,0.0000026626033,0.000004764814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991351,0.00002286238,0.0003252946,0.00009258144,0.00034189437,0.00008227914],"domain_scores_gemma":[0.99945855,0.000028686383,0.00018311325,0.000064763,0.00024955833,0.00001531927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069076766,0.00004833904,0.000106254614,0.00024483373,0.00002193389,0.000017649032,0.00035915445,0.000020229594,0.0000012341893],"category_scores_gemma":[0.00009029206,0.000036891983,0.00016987773,0.0004876775,0.000069717375,0.0000052581663,0.00002065301,0.000028751774,3.827931e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030166922,0.000037468602,0.0055846726,0.000006554154,0.00026121704,0.000008155584,0.0005076601,0.116152324,0.8703394,0.00007092429,0.0000124160215,0.006989072],"study_design_scores_gemma":[0.0005883173,0.0002977776,0.030325228,0.00007167563,0.00024685633,0.00004219948,0.0017663192,0.023462296,0.94270134,0.0002465317,0.00013578938,0.00011564548],"about_ca_topic_score_codex":0.00000831075,"about_ca_topic_score_gemma":0.000020021309,"teacher_disagreement_score":0.09269003,"about_ca_system_score_codex":0.000004173699,"about_ca_system_score_gemma":0.00007074395,"threshold_uncertainty_score":0.15044114},"labels":[],"label_agreement":null},{"id":"W4388125967","doi":"10.7554/elife.92819.1","title":"Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies","year":2023,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Endogeny; Induced pluripotent stem cell; Computational biology; Computer science; Biology; Genetics; Gene; Biochemistry","score_opus":0.0994170686717019,"score_gpt":0.4002061560582363,"score_spread":0.30078908738653437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388125967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9294091,0.011622126,0.05567119,0.00017577976,0.0011345891,0.0013318214,0.0000977529,0.00012567476,0.00043200704],"genre_scores_gemma":[0.9864535,0.00058948353,0.0108434595,0.000097060976,0.00064308697,0.00015541074,0.00032921202,0.00011105345,0.0007777865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983831,0.000023959816,0.00037800343,0.0006721047,0.000104612205,0.00043822272],"domain_scores_gemma":[0.99925905,0.00003267506,0.00009229005,0.00045506697,0.00010653356,0.00005439379],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031374933,0.00032706326,0.00037150263,0.00014877909,0.00009946531,0.000042954533,0.00026167592,0.00018771827,0.000004329765],"category_scores_gemma":[0.00010231249,0.00035155803,0.0001895566,0.00005913244,0.000047603644,0.000001663356,0.000961065,0.00020489727,0.0000033796357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027111932,0.00004433007,0.004399184,0.0010283127,0.00043319067,0.000051471907,0.0010070199,0.08248457,0.9073765,0.00009536262,0.0009037716,0.0021491603],"study_design_scores_gemma":[0.0036115232,0.0003875147,0.003517428,0.0020450517,0.0006372494,0.00015401434,0.010847861,0.06763317,0.88975143,0.0054936586,0.011313833,0.004607283],"about_ca_topic_score_codex":0.0002794097,"about_ca_topic_score_gemma":0.00034267353,"teacher_disagreement_score":0.057044387,"about_ca_system_score_codex":0.00006610884,"about_ca_system_score_gemma":0.000068387606,"threshold_uncertainty_score":0.99989367},"labels":[],"label_agreement":null},{"id":"W4388190534","doi":"10.1016/j.jclepro.2023.139512","title":"CRISPR/Cas9-Mediated genetically edited ornamental and aromatic plants: A promising technology in phytoremediation of heavy metals","year":2023,"lang":"en","type":"article","venue":"Journal of Cleaner Production","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; Dalhousie University","funders":"","keywords":"Phytoremediation; Ornamental plant; CRISPR; Genome editing; Genetically modified organism; Genetically modified crops; Biotechnology; Biology; Transgene; Botany; Ecology; Contamination; Gene","score_opus":0.008056698280071387,"score_gpt":0.282436867863047,"score_spread":0.2743801695829756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388190534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971794,0.0008651738,0.00074186135,0.00067422894,0.00038510756,0.0001341514,0.0000024184692,0.000009042323,0.000008621203],"genre_scores_gemma":[0.99781734,0.0007827505,0.0009575109,0.000010673162,0.00037469057,0.0000035976673,0.000017351671,0.000013101008,0.000022989621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912375,0.00003255595,0.00041200104,0.00014511403,0.00015254878,0.00013404626],"domain_scores_gemma":[0.9995705,0.000011310392,0.00019972681,0.00010977312,0.00007102348,0.00003765218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040947905,0.00008869181,0.00018205683,0.00033896792,0.000018174005,0.000007519976,0.00006409054,0.000099687175,0.0000017992672],"category_scores_gemma":[0.00038492525,0.00008063514,0.000035341458,0.00023877462,0.000050684917,0.000009399542,0.00003144005,0.000109523084,9.975216e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102958234,0.00004748522,0.0022318987,0.000053047635,0.00004334336,0.000006190095,0.00012462959,0.0026030752,0.98898685,0.0000011858862,0.00038156414,0.005417786],"study_design_scores_gemma":[0.0006674308,0.00043283656,0.021688176,0.00009212917,0.000028552307,0.00022235846,0.0005092395,0.00068977516,0.97448194,0.00022444062,0.0008561457,0.00010699724],"about_ca_topic_score_codex":0.0000019265467,"about_ca_topic_score_gemma":0.0000052596765,"teacher_disagreement_score":0.019456277,"about_ca_system_score_codex":0.000015632382,"about_ca_system_score_gemma":0.000031678206,"threshold_uncertainty_score":0.32882056},"labels":[],"label_agreement":null},{"id":"W4388214118","doi":"10.26508/lsa.202302045","title":"CRISPR/Cas9 bioluminescence-based assay for monitoring CFTR trafficking to the plasma membrane","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Institut de recherche, Centre universitaire de santé McGill; University of North Carolina at Chapel Hill; Canadian Institutes of Health Research; McGill University Health Centre; Ministère du Développement Économique, de l’Innovation et de l’Exportation; Cystic Fibrosis Foundation Therapeutics","keywords":"CRISPR; Cas9; Genome editing; Luciferase; Molecular biology; Bioluminescence; Biology; HEK 293 cells; Transfection; Chemistry; Cell biology; Gene; Genetics; Biochemistry","score_opus":0.025063003352224267,"score_gpt":0.33437697607168043,"score_spread":0.30931397271945615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388214118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94268084,0.0002940904,0.0521119,0.002664872,0.001521028,0.0005086135,0.000018469147,0.000086225366,0.00011399062],"genre_scores_gemma":[0.9939306,0.000059220692,0.00448639,0.00031306277,0.0006466785,0.00011853229,0.000008616751,0.000019974881,0.0004169195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850124,0.000014847439,0.00016978738,0.0005000049,0.00028023205,0.0005338666],"domain_scores_gemma":[0.99919194,0.000054728076,0.00003849557,0.0004280656,0.00011052568,0.0001762539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084783067,0.00014682555,0.00010800971,0.000062656705,0.00033447408,0.00009749707,0.0006908874,0.000058016107,0.000002536144],"category_scores_gemma":[0.0007270504,0.0001196192,0.000070353075,0.00089763664,0.00013447528,0.000008260656,0.000097671065,0.00006661623,0.000036818466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020969128,0.000009955572,0.001213772,0.000025164256,0.000006059118,0.0000010707402,0.00009547174,0.06829613,0.92366755,0.000018999717,0.0016891666,0.0049557146],"study_design_scores_gemma":[0.00022808394,0.00009470872,0.004277273,0.00004259168,0.0000062267845,0.0000015180365,0.00018505774,0.026136247,0.9257445,0.000002742394,0.043071765,0.00020929461],"about_ca_topic_score_codex":0.0000056573654,"about_ca_topic_score_gemma":0.0000126910345,"teacher_disagreement_score":0.051249795,"about_ca_system_score_codex":0.000016179043,"about_ca_system_score_gemma":0.00016294123,"threshold_uncertainty_score":0.48779294},"labels":[],"label_agreement":null},{"id":"W4388300859","doi":"10.1101/2023.11.01.565029","title":"An adaptable plasmid scaffold for CRISPR-based endogenous tagging","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Krembil Foundation; Canadian Institutes of Health Research; Government of Ontario; Ontario Genomics; Genome Canada","keywords":"CRISPR; Protocol (science); Computer science; Endogeny; Computational biology; Biology; Genetics; Medicine; Gene; Biochemistry","score_opus":0.024768658076096274,"score_gpt":0.2691831165232433,"score_spread":0.24441445844714701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388300859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7633871,0.003537592,0.22492047,0.00026310052,0.0032727164,0.002188303,0.0015265734,0.00088840484,0.000015732212],"genre_scores_gemma":[0.98149663,0.0001517687,0.015840523,0.0002751215,0.0011847445,0.00066652056,0.000014071019,0.00035440666,0.000016235037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968926,0.00006350382,0.00049503427,0.0013885285,0.00028249668,0.00087787904],"domain_scores_gemma":[0.99730796,0.000042271047,0.00022129733,0.0017113338,0.0003615887,0.00035552622],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055701885,0.00066635606,0.0005086144,0.0002298727,0.00022110506,0.00019719395,0.0007478276,0.0007387439,0.000012687519],"category_scores_gemma":[0.0001831442,0.00079804444,0.00029216302,0.00022292168,0.00007027739,0.00000886098,0.0003184272,0.00033633655,0.000024847875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006433722,0.000103337945,0.0005440489,0.00043441824,0.00016364589,0.000018267581,0.0000036251756,0.021291489,0.97615397,0.00005193142,0.0011683132,0.0000026033822],"study_design_scores_gemma":[0.0007233123,0.00023958656,0.001526449,0.00015537962,0.00014149306,3.4464602e-8,0.0000042726774,0.0077175805,0.9677661,0.0000013715986,0.020774256,0.0009501328],"about_ca_topic_score_codex":0.000052899057,"about_ca_topic_score_gemma":0.000011942645,"teacher_disagreement_score":0.2181095,"about_ca_system_score_codex":0.00008869616,"about_ca_system_score_gemma":0.0006084612,"threshold_uncertainty_score":0.99944705},"labels":[],"label_agreement":null},{"id":"W4388409498","doi":"10.1038/s41389-023-00497-9","title":"Combined in vitro/in vivo genome-wide CRISPR screens in triple negative breast cancer identify cancer stemness regulators in paclitaxel resistance","year":2023,"lang":"en","type":"article","venue":"Oncogenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Paclitaxel; CRISPR; Cancer; Breast cancer; In vivo; Triple-negative breast cancer; Biology; Cancer research; In vitro; Genetics; Gene","score_opus":0.010253065575693136,"score_gpt":0.30916381748258986,"score_spread":0.29891075190689675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388409498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957592,0.0025106717,0.000073662246,0.00044977723,0.00022809226,0.00043879356,0.00039172717,0.000020199443,0.00012791393],"genre_scores_gemma":[0.9960563,0.0018256382,0.00009424923,0.000093209965,0.00009067383,0.0003963935,0.000060214494,0.00005515393,0.0013281653],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9979698,0.000119911296,0.00051411794,0.0006177578,0.00019946272,0.0005789246],"domain_scores_gemma":[0.99934673,0.000047179623,0.00008500615,0.00037258686,0.000056528977,0.000091993046],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040080227,0.00027106836,0.0004056441,0.00041143238,0.000035267694,0.00002129477,0.0002594184,0.00021286664,0.000036364538],"category_scores_gemma":[0.00007028208,0.0003057773,0.0000880817,0.0013171975,0.000053286953,0.000011369797,0.00012333892,0.00014353741,0.0000035807666],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073004543,0.00010336446,0.30220214,0.00013373069,0.000037068698,0.00007992797,0.0004595003,0.009700118,0.68471825,0.000005527098,0.0006771685,0.0011531744],"study_design_scores_gemma":[0.0020099333,0.000020376678,0.73698527,0.00014240775,0.000009830755,0.0000010950378,0.0005437227,0.00032023486,0.2588073,0.000031523723,0.00079171493,0.0003366068],"about_ca_topic_score_codex":0.0057478193,"about_ca_topic_score_gemma":0.09883088,"teacher_disagreement_score":0.4347831,"about_ca_system_score_codex":0.00025893858,"about_ca_system_score_gemma":0.00016346533,"threshold_uncertainty_score":0.99993944},"labels":[],"label_agreement":null},{"id":"W4388477717","doi":"10.5376/jmr.2023.13.0001","title":"Application of CRISPRCas9 in Gene Editing of &lt;i&gt;Aedes aegypti&lt;/i&gt; Mosquitoes: Methods and Challenges","year":2023,"lang":"en","type":"article","venue":"Journal of Mosquito Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Aedes aegypti; CRISPR; Genome editing; Dengue fever; Biology; Yellow fever; Cas9; Aedes; Zika virus; Malaria; Virology; Ecology; Virus; Gene; Genetics; Immunology","score_opus":0.06482243572440358,"score_gpt":0.44533436895712153,"score_spread":0.3805119332327179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388477717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9660754,0.024306465,0.0083795125,0.00055475614,0.00013818243,0.00019258934,0.000008168463,0.0000050116596,0.00033992162],"genre_scores_gemma":[0.97215396,0.017672868,0.009546494,0.000004428996,0.0005266562,0.000014293139,0.000005703272,0.000024533007,0.00005105294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980741,0.00026190584,0.00059863436,0.00024002668,0.0004878221,0.00033749983],"domain_scores_gemma":[0.99869573,0.00020704414,0.00020234511,0.00030337853,0.00048376695,0.00010770745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004903146,0.00011953589,0.0003162607,0.00043743415,0.000045892924,0.0000141205455,0.00032304262,0.00016589805,0.0000043875266],"category_scores_gemma":[0.00079410645,0.000111365815,0.00009323018,0.0004125861,0.00013111967,0.000009671077,0.0002568947,0.0002372156,0.0000010446431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005688481,0.00005080276,0.0003251773,0.0002570969,0.00004577772,0.00000674279,0.00029084965,0.0013116504,0.9327281,0.00015300159,0.00036005533,0.06441383],"study_design_scores_gemma":[0.0006287993,0.00058981555,0.016370691,0.00011202587,0.000016933905,0.000054844946,0.00075215567,0.0024078137,0.9655393,0.0003954578,0.0130116865,0.0001204828],"about_ca_topic_score_codex":0.000009355922,"about_ca_topic_score_gemma":0.000029979443,"teacher_disagreement_score":0.06429335,"about_ca_system_score_codex":0.000023101347,"about_ca_system_score_gemma":0.00009527342,"threshold_uncertainty_score":0.4541366},"labels":[],"label_agreement":null},{"id":"W4388489852","doi":"10.1016/j.cell.2023.09.025","title":"Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions","year":2023,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Tianjin University; Tsinghua University; Macquarie University; Volkswagen Foundation; York University; Johns Hopkins University; Imperial College London; National Cancer Institute; National Institutes of Health; National University of Singapore; National Science Foundation","keywords":"Biology; Genetics; CRISPR; Genome; Computational biology; Chromosome; Cas9; Gene","score_opus":0.008436221517023185,"score_gpt":0.27584892714719783,"score_spread":0.26741270563017466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388489852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99662095,0.00062706735,0.0011658885,0.000047240323,0.00052735145,0.00010766535,0.000008457345,0.00005197439,0.0008433774],"genre_scores_gemma":[0.9983067,0.00016447042,0.0006973278,0.000027183329,0.00021450759,0.000018189152,0.00003392318,0.000021990669,0.0005157049],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993832,0.000020939153,0.00012999786,0.00022019778,0.000053035143,0.00019260234],"domain_scores_gemma":[0.9996587,0.000047991824,0.000029553808,0.00017686102,0.000022484937,0.0000644243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007135641,0.00010007885,0.0000920779,0.000044308694,0.00008600094,0.000025861082,0.000069634094,0.000050877425,0.000015231432],"category_scores_gemma":[0.0000909704,0.0001074566,0.00003563135,0.00007857268,0.000032232714,0.0000019516863,0.00009936949,0.000061339844,0.000028947867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000051133416,0.000012877809,0.0024755173,0.000040864405,0.0000138981795,0.0000048655334,0.00008370322,0.0004874725,0.99464566,0.000009442612,0.0011581084,0.0010624707],"study_design_scores_gemma":[0.0008079966,0.000097299,0.008717496,0.000045241315,0.000034393703,0.000040314044,0.0002466219,0.0054454138,0.9657032,0.00019922465,0.018347695,0.00031509096],"about_ca_topic_score_codex":0.0000064193046,"about_ca_topic_score_gemma":0.0000056996805,"teacher_disagreement_score":0.028942455,"about_ca_system_score_codex":0.0000056014956,"about_ca_system_score_gemma":0.000018231987,"threshold_uncertainty_score":0.43819532},"labels":[],"label_agreement":null},{"id":"W4388569053","doi":"10.3390/ijms242216161","title":"CRISPR/Cas9 Directed Reprogramming of iPSC for Accelerated Motor Neuron Differentiation Leads to Dysregulation of Neuronal Fate Patterning and Function","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Defense Threat Reduction Agency","keywords":"Induced pluripotent stem cell; Reprogramming; Biology; Motor neuron; Cellular differentiation; Cell biology; Neuroscience; Directed differentiation; Transcriptome; Neurodegeneration; Cell fate determination; Embryonic stem cell; Genetics; Cell; Transcription factor; Gene expression; Gene; Disease","score_opus":0.02042083507305103,"score_gpt":0.32481289023230336,"score_spread":0.30439205515925233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388569053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90487164,0.000108091044,0.09439296,0.00015620112,0.00036513267,0.000085986554,0.0000073184247,0.0000056419162,0.0000070275473],"genre_scores_gemma":[0.99832016,0.00003591224,0.0014831063,0.000033801913,0.00008324696,0.0000037499287,0.000018289595,0.000007353839,0.000014374095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913913,0.000027798742,0.00029563616,0.0001509412,0.00029234152,0.00009415344],"domain_scores_gemma":[0.9992933,0.000023627947,0.00022065996,0.000057530528,0.00036821511,0.000036651887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028987203,0.00007055266,0.0000998332,0.00021495257,0.000030251073,0.000030936462,0.00016427366,0.00003453482,0.0000023731423],"category_scores_gemma":[0.00017090992,0.00006593982,0.00006723235,0.00016049962,0.000039379647,0.000014144636,0.000056033972,0.000035452857,1.5970608e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010620755,0.000015448013,0.0062332666,0.00001232097,0.000034330136,0.0000013410745,0.00005155261,0.01314851,0.96786326,0.000022159973,0.000023996985,0.012487609],"study_design_scores_gemma":[0.00040181138,0.0007727959,0.2044769,0.00004473781,0.000022875147,0.00001247522,0.000054452263,0.010513898,0.78335756,0.000059402122,0.0002071058,0.00007600618],"about_ca_topic_score_codex":0.0000050044364,"about_ca_topic_score_gemma":0.000002740757,"teacher_disagreement_score":0.19824363,"about_ca_system_score_codex":0.0000059694253,"about_ca_system_score_gemma":0.000027515507,"threshold_uncertainty_score":0.2688948},"labels":[],"label_agreement":null},{"id":"W4388680084","doi":"10.1101/2023.11.11.566649","title":"Proteome-wide base editor screens to assess phosphorylation site functionality in high-throughput","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Phosphoproteomics; NFAT; Phosphorylation; Biology; Computational biology; Proteome; Transcription factor; Phenotype; Signal transduction; Function (biology); Gene; Cell biology; Protein phosphorylation; Genetics; Protein kinase A","score_opus":0.01827859643517177,"score_gpt":0.2648798298902775,"score_spread":0.2466012334551057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388680084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9269392,0.0003282702,0.065591216,0.00039778338,0.0048529063,0.0011374921,0.00056116085,0.00018869576,0.000003279977],"genre_scores_gemma":[0.98494124,0.00011078991,0.009604581,0.0002357797,0.0043170652,0.00057418394,0.000018710016,0.0001621695,0.000035472192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99713916,0.00009973388,0.0005389391,0.0012739559,0.00039193576,0.0005563027],"domain_scores_gemma":[0.99793655,0.000041615138,0.00017288375,0.0012132835,0.00036458808,0.00027108836],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075144053,0.000510581,0.00041916172,0.00023554424,0.00008935622,0.000115995696,0.00036693254,0.00065416057,0.000023567905],"category_scores_gemma":[0.00056828366,0.00061103416,0.00014318478,0.00047181628,0.000045959194,0.000010630232,0.00067871704,0.00051096623,0.00013001857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007571897,0.0000894146,0.031156756,0.00024589652,0.000086022344,0.000020055493,0.0000059027884,0.012881009,0.94871944,0.000023834838,0.0066942684,0.0000017059554],"study_design_scores_gemma":[0.000461586,0.0000873421,0.42604324,0.00019537602,0.00003877204,9.159479e-9,0.0000029615314,0.00034899896,0.5568843,0.000002122645,0.015205648,0.00072962453],"about_ca_topic_score_codex":0.0002475818,"about_ca_topic_score_gemma":0.00006334059,"teacher_disagreement_score":0.3948865,"about_ca_system_score_codex":0.00017425414,"about_ca_system_score_gemma":0.00037910166,"threshold_uncertainty_score":0.9996341},"labels":[],"label_agreement":null},{"id":"W4388753921","doi":"10.1016/j.trac.2023.117431","title":"CRISPR-associated “genetic scissors” for multiplexing analysis","year":2023,"lang":"en","type":"article","venue":"TrAC Trends in Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Multiplexing; Computational biology; Computer science; Nanotechnology; Biology; Genetics; Gene; Telecommunications","score_opus":0.020904414267652525,"score_gpt":0.36491879326824544,"score_spread":0.3440143790005929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388753921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872232,0.00024035313,0.009380293,0.00020640572,0.0000658931,0.00008490519,0.000120732846,0.000094479925,0.0025837447],"genre_scores_gemma":[0.9931427,0.000037056383,0.0006275144,0.000031301155,0.00014409452,0.000042325413,0.00087130006,0.000033577173,0.005070133],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99838287,0.000016049356,0.0003680555,0.0005382797,0.00017153687,0.00052323006],"domain_scores_gemma":[0.99932253,0.000056002697,0.000050089217,0.00036795854,0.000054144555,0.00014926612],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024550076,0.00022080792,0.0003155748,0.00023523255,0.00005692632,0.00003008933,0.00023139197,0.00025761698,0.00012745538],"category_scores_gemma":[0.00028872053,0.00023956613,0.0003875009,0.0016667373,0.000060973394,0.0000024371277,0.00007011135,0.00013716148,0.000008096936],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026369578,0.0005909273,0.076623,0.0002548264,0.0026876691,0.0000767647,0.00019275738,0.218363,0.66356707,0.00004876174,0.017783474,0.019548072],"study_design_scores_gemma":[0.0028274523,0.00013930305,0.2731912,0.00003830966,0.00089601905,0.000007137738,0.00019077971,0.4076232,0.30580655,0.00013258755,0.008033303,0.0011141303],"about_ca_topic_score_codex":0.000013732242,"about_ca_topic_score_gemma":0.000075802185,"teacher_disagreement_score":0.35776052,"about_ca_system_score_codex":0.000034937962,"about_ca_system_score_gemma":0.000023379866,"threshold_uncertainty_score":0.9769223},"labels":[],"label_agreement":null},{"id":"W4388757474","doi":"10.21203/rs.3.rs-3420578/v1","title":"Dependence of Human Cell Survival and Proliferation on the CASP3 Prodomain","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Provincial Health Services Authority; Terry Fox Research Institute; BC Cancer Agency","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Cell growth; Cell; Cell biology; Cell survival; Cancer research; Biology; Chemistry; Cell culture; Genetics","score_opus":0.06740776724668612,"score_gpt":0.4179824753156534,"score_spread":0.3505747080689673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388757474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967636,0.000528847,0.00052931625,0.0002892944,0.00008579038,0.00077741715,0.000045239623,0.0000114046225,0.0009690976],"genre_scores_gemma":[0.9981525,0.00032490405,0.000055079006,0.0000041893277,0.00019892298,0.00012703374,0.000105180654,0.0000272257,0.0010049712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862295,0.00020994099,0.00015417667,0.00037174823,0.00040822112,0.0002329334],"domain_scores_gemma":[0.99915105,0.00007494846,0.00003738205,0.00050888787,0.00017585703,0.000051880274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012304654,0.00012177562,0.00012060091,0.00007508542,0.00011593043,0.000041285228,0.00023741997,0.00018836565,0.0000071536565],"category_scores_gemma":[0.00023776866,0.00009366364,0.0000501321,0.0000788052,0.00009174039,7.5640213e-7,0.00061988225,0.0004382104,0.0000051487377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006847537,0.00008853151,0.005268624,0.0015146269,0.000053053438,0.000011276643,0.00035857625,0.0024699618,0.9864824,0.0010229632,0.0021074049,0.0005541143],"study_design_scores_gemma":[0.00023818263,0.00064566446,0.016703032,0.00025842647,0.000008779717,0.0000019754686,0.00056119444,0.00048205638,0.9792665,0.0010378807,0.00058389583,0.00021239619],"about_ca_topic_score_codex":0.00007448884,"about_ca_topic_score_gemma":0.00016663194,"teacher_disagreement_score":0.011434409,"about_ca_system_score_codex":0.000013384735,"about_ca_system_score_gemma":0.00009714767,"threshold_uncertainty_score":0.38194925},"labels":[],"label_agreement":null},{"id":"W4388765308","doi":"10.1101/2023.11.15.567075","title":"Genetically encoded affinity reagents (GEARs): A toolkit for visualizing and manipulating endogenous protein function <i>in vivo</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Surdna Foundation; Yale University","keywords":"Genome editing; Computational biology; CRISPR; Biology; Cas9; Function (biology); Epitope; Gene; Cell biology; Genetics; Antibody","score_opus":0.02897452212729375,"score_gpt":0.26859360882779776,"score_spread":0.239619086700504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388765308","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9607684,0.0010740061,0.035709593,0.000032515643,0.0005158444,0.0015849276,0.00016327467,0.00014235788,0.000009080399],"genre_scores_gemma":[0.98895913,0.00022089618,0.009381138,0.000069918635,0.0005004726,0.00066649436,0.0000030930216,0.00018078389,0.000018041706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973987,0.000082066654,0.00055763626,0.0011257199,0.00022121168,0.0006147064],"domain_scores_gemma":[0.99868,0.000035519835,0.0001971189,0.0007201293,0.00018103959,0.00018620906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00063441135,0.00049138867,0.000423329,0.00017314046,0.00013223951,0.00013723662,0.00027445194,0.0005954471,0.0000055800097],"category_scores_gemma":[0.00032299652,0.000595176,0.0001418233,0.00019709126,0.000051515235,0.000007410418,0.00053387415,0.000335659,0.0000050220483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089176974,0.000057814683,0.00204643,0.0005259406,0.00009493305,0.000015946447,0.0000073522383,0.00096306234,0.9960617,0.000072496296,0.000056916007,0.00000826059],"study_design_scores_gemma":[0.00092100573,0.00025527316,0.014019753,0.00034372948,0.00009368611,9.520319e-8,0.0000069505345,0.0024599778,0.9795323,0.000009157431,0.001548049,0.00081003545],"about_ca_topic_score_codex":0.000047634672,"about_ca_topic_score_gemma":0.000025601956,"teacher_disagreement_score":0.028190762,"about_ca_system_score_codex":0.000067039735,"about_ca_system_score_gemma":0.00019750417,"threshold_uncertainty_score":0.99964994},"labels":[],"label_agreement":null},{"id":"W4388826313","doi":"10.1016/j.tig.2023.10.012","title":"Next-generation forward genetic screens: uniting high-throughput perturbations with single-cell analysis","year":2023,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; National Human Genome Research Institute; York University","keywords":"CRISPR; Biology; Genome editing; Computational biology; Epigenome; Phenotype; Genome; Transcriptome; Genome engineering; CRISPR interference; Gene; Genetics; Massively parallel; Computer science; Gene expression","score_opus":0.09247887544715454,"score_gpt":0.35278867823612065,"score_spread":0.2603098027889661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388826313","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002999519,0.9764645,0.019348942,0.000017526294,0.0001962452,0.0003419486,0.00015711699,0.000059281425,0.00041491952],"genre_scores_gemma":[0.0053709666,0.97293663,0.013099625,0.000026676069,0.00076473947,0.00014372934,0.005033582,0.00020745811,0.0024166116],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971954,0.0001402974,0.00084619113,0.00094392046,0.00030450436,0.0005696735],"domain_scores_gemma":[0.9984592,0.000049092887,0.0002958973,0.00095118297,0.000107522515,0.00013705847],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016758223,0.00066138175,0.0010969322,0.0010242611,0.00010908287,0.000116692994,0.00041481506,0.0005340044,0.00003632024],"category_scores_gemma":[0.000035096466,0.0006155409,0.00047301527,0.0024005056,0.00007513394,0.0000047562885,0.00018748168,0.0002952454,0.00001906262],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010373451,0.00018720585,0.00024952734,0.0022355677,0.0017425033,0.000042903244,0.0001072862,0.0815714,0.0019606457,0.000016352928,0.0011077479,0.9107685],"study_design_scores_gemma":[0.0013371521,0.001199232,0.0006456135,0.0015704748,0.01297608,0.00006354951,0.00015712297,0.011350545,0.0019525063,0.000014438575,0.96566874,0.0030645244],"about_ca_topic_score_codex":0.000047302958,"about_ca_topic_score_gemma":0.0010477345,"teacher_disagreement_score":0.964561,"about_ca_system_score_codex":0.00008190757,"about_ca_system_score_gemma":0.00013324928,"threshold_uncertainty_score":0.9996296},"labels":[],"label_agreement":null},{"id":"W4388852098","doi":"10.15252/msb.202311801","title":"A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration","year":2023,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Korea University; National Research Foundation; Government of Canada","keywords":"Biology; Neurodegeneration; Disease; Neuroscience; Spinocerebellar ataxia; AKT1; Cellular model; Bioinformatics; Ataxia; Computational biology; Signal transduction; PI3K/AKT/mTOR pathway; Genetics; Medicine; Internal medicine","score_opus":0.013786880514834102,"score_gpt":0.3242981701675886,"score_spread":0.3105112896527545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388852098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81031144,0.001859977,0.18684433,0.000040325223,0.00051173626,0.00027929904,0.000025293233,0.000049754428,0.000077862074],"genre_scores_gemma":[0.9981383,0.00010389013,0.00068454875,0.00006715688,0.00015427635,0.00007328349,0.00031445437,0.000041454714,0.00042261305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864066,0.00012960477,0.00038261776,0.00040822005,0.00009756489,0.00034132265],"domain_scores_gemma":[0.99923307,0.000009495636,0.000108878696,0.0004911634,0.00008663975,0.00007076077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002403722,0.00019596859,0.00028613728,0.000087289896,0.000059488102,0.00001883139,0.00021357626,0.00024796996,0.0000013727345],"category_scores_gemma":[0.00006010157,0.00019963576,0.00012483765,0.00021343624,0.000053951255,0.0000025146953,0.00015275498,0.00007532321,0.000020331505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013920003,0.000011330126,0.00052453706,0.00003129466,0.000044007233,0.000004450834,0.000018966595,0.3748497,0.62371063,0.00033576234,0.00036264842,0.000092721486],"study_design_scores_gemma":[0.00048804536,0.00020208096,0.00046057114,0.000024549825,0.000024397259,0.000025288879,0.000035483088,0.49566367,0.5016307,0.00015816605,0.0010212042,0.00026581078],"about_ca_topic_score_codex":0.00008709919,"about_ca_topic_score_gemma":0.000030505349,"teacher_disagreement_score":0.18782692,"about_ca_system_score_codex":0.000008213826,"about_ca_system_score_gemma":0.0000423714,"threshold_uncertainty_score":0.81409097},"labels":[],"label_agreement":null},{"id":"W4388866199","doi":"10.1186/s13100-023-00306-5","title":"Proceedings of the inaugural Dark Genome Symposium: November 2022","year":2023,"lang":"en","type":"article","venue":"Mobile DNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Institute on Aging; Francis Crick Institute","keywords":"Session (web analytics); Library science; Sociology; Engineering ethics; Engineering; Computer science","score_opus":0.003941069401546494,"score_gpt":0.24606524992864606,"score_spread":0.24212418052709958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388866199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958218,0.00019285304,0.00001864324,0.00007344202,0.00015668194,0.00017686232,0.000016204041,0.000017203827,0.0035263433],"genre_scores_gemma":[0.9964965,0.00008277459,0.000026546002,0.00004528649,0.00011544161,0.000059079808,0.000022070086,0.000016995478,0.003135318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999467,0.0000031033378,0.000112433765,0.00016323668,0.000094072566,0.00016016577],"domain_scores_gemma":[0.9997405,0.0000031752027,0.00003084262,0.0001547911,0.0000417423,0.000028962393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000084559695,0.00008226837,0.00007569094,0.000023117851,0.000037730428,0.000008661685,0.00018348181,0.000059474638,0.00001953009],"category_scores_gemma":[0.000011747572,0.00006429069,0.00007156534,0.00018709427,0.000035542016,0.0000014680897,0.00016623296,0.000051522486,0.000011723139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005462236,0.000010615626,0.0015881879,0.000025876221,0.000014622813,2.853243e-7,0.000076242395,0.0005043762,0.9933822,0.000020706058,0.004181528,0.00018989113],"study_design_scores_gemma":[0.00018285001,0.00009439312,0.018696476,0.000008144187,0.000011042048,0.000006490226,0.00014903354,0.00008208541,0.9195202,0.000025467232,0.061107494,0.00011631695],"about_ca_topic_score_codex":0.000003959431,"about_ca_topic_score_gemma":0.000002730521,"teacher_disagreement_score":0.073862,"about_ca_system_score_codex":0.000005956462,"about_ca_system_score_gemma":0.000014331114,"threshold_uncertainty_score":0.26216984},"labels":[],"label_agreement":null},{"id":"W4388961044","doi":"10.1007/s00294-023-01279-x","title":"Correction: TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks","year":2023,"lang":"en","type":"erratum","venue":"Current Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Replication (statistics); Genetics; Gene silencing; Link (geometry); Gene; Computational biology; Computer science; Virology; Computer network","score_opus":0.020584657592992855,"score_gpt":0.32438934002275965,"score_spread":0.30380468242976677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388961044","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.28115943,0.56715757,0.07671767,0.0011399707,0.06902293,0.0025316589,0.00044217354,0.00014323737,0.001685329],"genre_scores_gemma":[0.6700867,0.2727119,0.0020094707,0.00008934055,0.027946228,0.00018724821,0.004330615,0.0003680881,0.022270398],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986525,0.000051123072,0.00038967983,0.00052673375,0.00016248718,0.00021746824],"domain_scores_gemma":[0.9988911,0.000055163786,0.00021229303,0.0006566106,0.00011233725,0.0000724709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033724474,0.00025028773,0.00032398562,0.00006392708,0.000103994644,0.00002748107,0.00016371466,0.0003529602,0.0000011285574],"category_scores_gemma":[0.00018232487,0.00021759127,0.00008688907,0.000120626886,0.00015803457,0.0000015462157,0.0002854858,0.00037768052,8.7465014e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006453578,0.000018253055,0.0020374197,0.0010248964,0.0002852196,0.0000012857614,0.0006024119,0.00060452573,0.053338677,0.000010871239,0.38868693,0.553325],"study_design_scores_gemma":[0.0025461598,0.0005676247,0.025964458,0.001436272,0.0011652285,0.00008295,0.00026247156,0.009172823,0.19888383,0.00040770732,0.758018,0.0014924576],"about_ca_topic_score_codex":0.000011035399,"about_ca_topic_score_gemma":0.000012217156,"teacher_disagreement_score":0.55183256,"about_ca_system_score_codex":0.000012621475,"about_ca_system_score_gemma":0.00008122648,"threshold_uncertainty_score":0.88731146},"labels":[],"label_agreement":null},{"id":"W4389029330","doi":"10.20944/preprints202311.1585.v1","title":"First Correction by Prime Editing of a Mutation in the RYR1 Gene Responsible for a Myopathy","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"RYR1; Mutation; Gene; Point mutation; Genetics; Myopathy; Ryanodine receptor; Genome editing; Biology; Genome; Receptor","score_opus":0.05439985595946149,"score_gpt":0.36233926141135714,"score_spread":0.30793940545189563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389029330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96701694,0.00033387175,0.030314427,0.00025173277,0.0010166668,0.0008356562,0.000068918904,0.000029050812,0.00013271661],"genre_scores_gemma":[0.99763733,0.0001663045,0.0004834087,0.000028472477,0.0003213658,0.0004487393,0.00041100962,0.000038514354,0.00046482665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986912,0.00007278443,0.00036727748,0.0005160276,0.0001445232,0.00020819374],"domain_scores_gemma":[0.99903345,0.00008085572,0.00018004286,0.0005823865,0.00009439333,0.000028883822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092491106,0.0001806628,0.00019295509,0.000089181856,0.00005149801,0.000010472205,0.0003073296,0.00026393024,0.000008570701],"category_scores_gemma":[0.00071131095,0.00017734023,0.0001352693,0.000110145214,0.000031063308,0.0000022016602,0.00037859252,0.00022925228,0.00001150731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018574006,0.000097584256,0.03273079,0.0002571565,0.00007551705,0.0000040471123,0.001272856,0.028030863,0.9354915,0.000007475445,0.0012698506,0.000576614],"study_design_scores_gemma":[0.00033271953,0.00006863078,0.048978824,0.000108316424,0.00003088582,0.000009926115,0.0003266642,0.0030238454,0.94496363,0.0001664452,0.0018064736,0.00018362838],"about_ca_topic_score_codex":0.00014570472,"about_ca_topic_score_gemma":0.00013101788,"teacher_disagreement_score":0.030620398,"about_ca_system_score_codex":0.0000291621,"about_ca_system_score_gemma":0.00009091741,"threshold_uncertainty_score":0.7231725},"labels":[],"label_agreement":null},{"id":"W4389033069","doi":"10.5376/rgg.2023.14.0003","title":"Molecular Mechanism Analysis of Improving the Development of Rice Growth Organs Using Gene Editing Technology","year":2023,"lang":"en","type":"article","venue":"Rice Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Biotechnology; Biology; Genome editing; Food security; Panicle; Agriculture; Gene; Agronomy; Ecology; Genetics","score_opus":0.007635061575950787,"score_gpt":0.2475618566027648,"score_spread":0.23992679502681402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389033069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86673415,0.0012238981,0.13179547,0.00002797714,0.00006950546,0.00010228708,0.000020633506,0.00001008195,0.000016022377],"genre_scores_gemma":[0.97376525,0.00035270624,0.025735581,0.000019191133,0.000052029463,0.0000049631526,0.000036259815,0.000025648094,0.000008344774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897283,0.000017013817,0.00037061455,0.0002773549,0.0001177838,0.00024437552],"domain_scores_gemma":[0.9993377,0.000015246246,0.00016063958,0.0003064005,0.00013584203,0.000044192187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028338554,0.0001497391,0.00022533997,0.00027771178,0.00010006394,0.000010950844,0.00022059005,0.00013728709,0.00000105259],"category_scores_gemma":[0.000042590487,0.00013812106,0.00007794626,0.00089648704,0.00006228648,0.0000013500418,0.00032181348,0.00006857078,4.3668106e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000035462053,0.000010069331,0.0004918456,0.000055830333,0.0003775053,0.0000010624224,0.0003126465,0.009440929,0.98816264,0.0000837661,0.0000018798022,0.0010582898],"study_design_scores_gemma":[0.00014045284,0.000042877677,0.0025753246,0.000004470953,0.00035588673,0.0000046604578,0.00056435214,0.023235166,0.9727262,0.0001086247,0.000095679796,0.00014627841],"about_ca_topic_score_codex":0.000013403912,"about_ca_topic_score_gemma":0.000013196746,"teacher_disagreement_score":0.107031144,"about_ca_system_score_codex":0.000013687382,"about_ca_system_score_gemma":0.000084634135,"threshold_uncertainty_score":0.5632413},"labels":[],"label_agreement":null},{"id":"W4389131303","doi":"10.1371/journal.pone.0294732","title":"The telomere resolvase, TelA, utilizes an underwound pre-cleavage intermediate to promote hairpin telomere formation","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Global Institute for Water Security; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Telomere; Cell biology; Cleavage (geology); Telomerase; Biology; Genetics; DNA; Gene","score_opus":0.028011882531018512,"score_gpt":0.29216385130760947,"score_spread":0.264151968776591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389131303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968324,0.00037697886,0.0009565435,0.00031292567,0.00009093112,0.00046717853,0.000026260359,0.00009208105,0.00084474904],"genre_scores_gemma":[0.99687684,0.00036197237,0.00060532324,0.00009659918,0.00022490363,0.000089223504,0.00013614357,0.00003650553,0.0015724732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893284,0.000033854383,0.00021456728,0.00027201494,0.00020645063,0.0003402692],"domain_scores_gemma":[0.99928886,0.000017656854,0.000041649935,0.00046771188,0.00005547681,0.0001286596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021754252,0.00015174538,0.0001307334,0.0000621248,0.0001697402,0.00007626645,0.00026503374,0.000098805904,0.000008369083],"category_scores_gemma":[0.00013211035,0.00012610506,0.00004485979,0.00019948375,0.000040869316,0.000010398346,0.00016532837,0.00010591795,0.000099124816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012032179,0.0001912138,0.00046677078,0.00012596988,0.00015156806,0.0000047192502,0.0006841776,0.00031881404,0.97946113,0.00007100649,0.00406848,0.014335852],"study_design_scores_gemma":[0.00038688563,0.00065326545,0.011708446,0.00010634636,0.00004342656,0.0000038728217,0.00046225276,0.003263171,0.9720905,0.0002610178,0.010707547,0.00031327378],"about_ca_topic_score_codex":0.000008640904,"about_ca_topic_score_gemma":0.00017870673,"teacher_disagreement_score":0.0140225785,"about_ca_system_score_codex":0.000017211063,"about_ca_system_score_gemma":0.00002449692,"threshold_uncertainty_score":0.5142415},"labels":[],"label_agreement":null},{"id":"W4389192597","doi":"10.22215/etd/2023-15700","title":"Targeted deletion of repeat sequences in the 3’UTR of MDM2 using CRISPR/Cas9","year":2023,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"CRISPR; Biology; Mdm2; Ubiquitin ligase; Untranslated region; Gene; Genetics; Cas9; Five prime untranslated region; Messenger RNA; Molecular biology; Computational biology; Ubiquitin","score_opus":0.01595354355974039,"score_gpt":0.34755425358887376,"score_spread":0.3316007100291334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389192597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99634844,0.0013300289,0.00096520706,0.000011615583,0.00030010738,0.00016777171,0.00001304137,0.0000062906515,0.00085750886],"genre_scores_gemma":[0.9971666,0.00041804003,0.0005823274,0.000011638099,0.000065517204,0.000010127292,0.00078100903,0.00002142816,0.0009433217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991806,0.000036687594,0.00031446814,0.00020012811,0.00014482668,0.0001232584],"domain_scores_gemma":[0.99952,0.000015143505,0.000121289944,0.00024226341,0.000087596796,0.00001373028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002069236,0.00013170618,0.0001791326,0.000089974004,0.000016872127,0.0000055133896,0.00016979247,0.00021487,0.000012716286],"category_scores_gemma":[0.00007177098,0.000103449245,0.000094327464,0.00017373575,0.000021079666,0.0000012160264,0.000016435217,0.00008547834,7.565673e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030129577,0.000016583024,0.00030948783,0.00020406539,0.000029941375,0.0000019794638,0.00035802266,0.0022623779,0.9959577,0.00002582119,0.00027774996,0.0005261907],"study_design_scores_gemma":[0.00013431373,0.00009618074,0.0045449757,0.00009777099,0.00003698141,0.0000035555852,0.0030474984,0.0004052397,0.99113435,0.000048980462,0.00030785953,0.00014232194],"about_ca_topic_score_codex":0.00043531906,"about_ca_topic_score_gemma":0.00089210423,"teacher_disagreement_score":0.0048233294,"about_ca_system_score_codex":0.000006388774,"about_ca_system_score_gemma":0.00006002948,"threshold_uncertainty_score":0.42185378},"labels":[],"label_agreement":null},{"id":"W4389230336","doi":"10.1182/blood-2023-185068","title":"Lipid Nanoparticle-Mediated Gene Editing of Human Primary T Cells and Off-Target Analysis of the CRISPR-Cas9 Indels","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Precision Nanosystems (Canada)","funders":"","keywords":"CRISPR; Cas9; Genome editing; Electroporation; Biology; Computational biology; Molecular biology; Gene; Genetics","score_opus":0.006419948274681695,"score_gpt":0.2510793971740688,"score_spread":0.2446594488993871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389230336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990106,0.0005336104,0.00011517782,0.000024069075,0.00006986181,0.00007860982,0.00006309079,0.000010102412,0.00009483642],"genre_scores_gemma":[0.99945474,0.000102724334,0.00016654607,0.000028240538,0.000098404795,0.000005339708,0.000075774165,0.000011963263,0.00005627256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993011,0.000026830881,0.00022731659,0.00017296906,0.00011600989,0.0001557845],"domain_scores_gemma":[0.99954844,0.000017812441,0.00008369017,0.00026329467,0.000047269183,0.000039495262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016494007,0.000087875604,0.00017960841,0.0000779379,0.000040524224,0.000005215759,0.00012082062,0.000072179384,0.000006762269],"category_scores_gemma":[0.000039532995,0.000073614734,0.00010100563,0.0004271412,0.00005317725,0.0000016834243,0.0001473628,0.00004470129,6.603496e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000032861556,0.000050781753,0.019848337,0.000034206052,0.00032617155,7.946523e-7,0.00010579817,0.0009032082,0.97848296,0.000002679432,0.00012538745,0.00011637943],"study_design_scores_gemma":[0.0003911178,0.00006434233,0.055715423,0.000007291072,0.0003363852,9.630648e-7,0.000053021893,0.0004311303,0.9427251,0.0000053900194,0.00019776204,0.00007205968],"about_ca_topic_score_codex":0.000011010177,"about_ca_topic_score_gemma":0.000012143123,"teacher_disagreement_score":0.035867084,"about_ca_system_score_codex":0.0000018905954,"about_ca_system_score_gemma":0.000017439934,"threshold_uncertainty_score":0.30019218},"labels":[],"label_agreement":null},{"id":"W4389230817","doi":"10.1182/blood-2023-189877","title":"Deciphering the Role of RAS Pathway Mutations in the Biology of Human Acute Myeloid Leukemia Using In Vivo Models","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital de l'Enfant-Jésus; Institute for Research in Immunology and Cancer; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Université Laval","funders":"","keywords":"Biology; Leukemia; Cancer research; Myeloid leukemia; Haematopoiesis; CD34; Myeloid; Neuroblastoma RAS viral oncogene homolog; Bone marrow; Stem cell; KRAS; Immunology; Mutation; Gene; Genetics","score_opus":0.014105004079062258,"score_gpt":0.29254426654296817,"score_spread":0.27843926246390593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389230817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99828047,0.0005254085,0.0007112897,0.000010710768,0.000018241546,0.00009955662,0.000014680398,0.000003851595,0.00033579484],"genre_scores_gemma":[0.9996404,0.0000693132,0.00020735395,0.000008840304,0.000027425927,0.000013909817,0.0000150132355,0.000008708878,0.000009034081],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994999,0.000036187324,0.00017748203,0.000110676934,0.00004563438,0.00013008846],"domain_scores_gemma":[0.99972016,0.000021380556,0.000037953494,0.00019462571,0.000016251377,0.000009616928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018052736,0.00006495861,0.000091914495,0.000047110672,0.000026575892,0.0000033898841,0.00016803881,0.00006279485,0.000001994143],"category_scores_gemma":[0.00001531975,0.00004687155,0.00004080548,0.00018956837,0.0000411445,0.0000017011279,0.00006232726,0.000056103574,2.2432796e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002627343,0.000021662328,0.0019580943,0.00000611559,0.000021744867,0.0000012921606,0.0006366472,0.034035686,0.96278495,0.0002652504,0.0000016269249,0.00026430862],"study_design_scores_gemma":[0.0004107318,0.00005445188,0.0019518282,0.000013824706,0.000019900424,0.000005684035,0.0008888239,0.005940574,0.9894005,0.0011490016,0.00010221789,0.00006246551],"about_ca_topic_score_codex":0.00013331886,"about_ca_topic_score_gemma":0.0001916127,"teacher_disagreement_score":0.028095111,"about_ca_system_score_codex":0.0000048332067,"about_ca_system_score_gemma":0.000035697605,"threshold_uncertainty_score":0.19113664},"labels":[],"label_agreement":null},{"id":"W4389233276","doi":"10.1182/blood-2023-182099","title":"UM171 Enhances Fitness and Engraftment of Gene Modified Hematopoietic Stem Cells from Sickle Cells Disease Patients","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Haematopoiesis; Stem cell; Genetic enhancement; Ex vivo; CD34; Cancer research; Biology; Hematopoietic stem cell; Viral vector; Immunology; CD90; Myeloid; Cell biology; In vivo; Gene; Genetics","score_opus":0.006413821601569239,"score_gpt":0.23339007174295065,"score_spread":0.2269762501413814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389233276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976971,0.0011295093,0.0006705611,0.000009090392,0.00013170356,0.0001566302,0.00015721485,0.000016703067,0.00003145017],"genre_scores_gemma":[0.9990856,0.0003227499,0.00019992636,0.000013674793,0.000060199513,0.000021957705,0.000108747,0.000017262495,0.0001698576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929047,0.000016543561,0.00016051692,0.0002567491,0.00011324391,0.00016249761],"domain_scores_gemma":[0.9995718,0.000013863605,0.00004272377,0.00024024112,0.000030058784,0.00010131082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000040342355,0.00012253186,0.00013108086,0.000026691894,0.0000286183,0.000010307173,0.000095841846,0.00005416782,0.000006031482],"category_scores_gemma":[0.00000407172,0.000118650445,0.00005052835,0.000061102626,0.000029301587,0.0000017273102,0.00008018371,0.000028321114,0.0000072174585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017917571,0.00015773583,0.0009285827,0.000067538596,0.000053517382,0.0000034510797,0.00012534327,0.000624198,0.9974822,0.0000033228894,0.00010940634,0.00042678503],"study_design_scores_gemma":[0.0008626842,0.000080876955,0.0052253287,0.000017874092,0.00006146107,1.7684309e-7,0.000054527,0.00015379352,0.9931765,0.000023748797,0.00020906558,0.00013394617],"about_ca_topic_score_codex":0.000010943405,"about_ca_topic_score_gemma":0.0000030744648,"teacher_disagreement_score":0.004305684,"about_ca_system_score_codex":0.0000020472535,"about_ca_system_score_gemma":0.000015591484,"threshold_uncertainty_score":0.48384246},"labels":[],"label_agreement":null},{"id":"W4389239981","doi":"10.1158/2326-6074.tumimm23-a045","title":"Abstract A045: Development of automated deep learning-based off-target distribution prediction system for CRISPR-Cas13 system","year":2023,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Computer science; RNA; Gene; Biology; Genetics","score_opus":0.027281087744333306,"score_gpt":0.3724679905078316,"score_spread":0.3451869027634983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389239981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95359373,0.0050807344,0.039236035,0.000059940474,0.00063182955,0.00072360464,0.00021941018,0.00036120118,0.00009352048],"genre_scores_gemma":[0.9972868,0.00011999561,0.00024845876,0.0000015095815,0.00010954509,0.0006218507,0.0014537707,0.000031165095,0.00012692751],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846536,0.00009921414,0.00036935994,0.00034867713,0.000213128,0.0005042764],"domain_scores_gemma":[0.9990658,0.00006532305,0.00008294649,0.00026541617,0.00046502307,0.000055504588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009750856,0.00013903576,0.00020478142,0.00014893251,0.00025499234,0.0000150602655,0.00021165003,0.00027163164,0.0000074509044],"category_scores_gemma":[0.00014820055,0.00014209263,0.000074915195,0.00033027504,0.00010061568,0.0000034760303,0.000094012066,0.00021008663,0.000016233893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038899257,0.000036775582,0.0016947967,0.0012875783,0.000270894,0.000003956629,0.00014110592,0.033993542,0.95388454,0.000032351338,0.0017833202,0.0064821257],"study_design_scores_gemma":[0.0010144456,0.00027690842,0.032930557,0.00020216365,0.000015542675,0.00000550644,0.0011614466,0.0681689,0.874279,0.0000010952205,0.02178284,0.00016159409],"about_ca_topic_score_codex":0.000026234837,"about_ca_topic_score_gemma":0.00001655828,"teacher_disagreement_score":0.07960556,"about_ca_system_score_codex":0.00023379739,"about_ca_system_score_gemma":0.00032381443,"threshold_uncertainty_score":0.57943696},"labels":[],"label_agreement":null},{"id":"W4389243648","doi":"10.1111/tpj.16575","title":"A rapid and highly efficient sorghum transformation strategy using <scp>GRF4‐GIF1</scp>/ternary vector system","year":2023,"lang":"en","type":"article","venue":"The Plant Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; China Agricultural University; Institute of Genetics; National Natural Science Foundation of China","keywords":"Sorghum; Transformation efficiency; Transformation (genetics); Agrobacterium; Plasmid; Biology; Mutant; Gene; Biotechnology; Agronomy; Genetics","score_opus":0.017358195779854743,"score_gpt":0.2554973463655982,"score_spread":0.23813915058574342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389243648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989189,0.0015489282,0.008493568,0.00005793208,0.00031471372,0.00009852329,0.00004125676,0.000023772325,0.00023226408],"genre_scores_gemma":[0.9989592,0.00050021923,0.00006239006,0.000016421618,0.00036290323,0.0000024069539,0.000026988291,0.000014136286,0.00005534855],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99928635,0.00004624198,0.00018981613,0.00010849296,0.00013391807,0.0002351719],"domain_scores_gemma":[0.9997083,0.000024043346,0.00005796373,0.00010670693,0.000024342278,0.0000786581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034307118,0.00011260338,0.00009993732,0.000058445763,0.00018989498,0.000067559224,0.00011606226,0.00006345688,0.0000017260602],"category_scores_gemma":[0.000012300416,0.00007992216,0.00005378646,0.00007598309,0.000022900562,0.0000034264629,0.000029650753,0.00013555895,0.000006262334],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002701344,0.000014211861,0.00009017878,0.00008842123,0.0000925461,0.000041448107,0.0009891787,0.06724028,0.92890555,0.000089177,0.0007853238,0.0016366988],"study_design_scores_gemma":[0.002338675,0.00073049206,0.01252101,0.00039029136,0.00022879102,0.011827349,0.009549745,0.50033903,0.4466776,0.000048223643,0.014959808,0.00038901425],"about_ca_topic_score_codex":0.0000060217953,"about_ca_topic_score_gemma":0.0000023020734,"teacher_disagreement_score":0.48222792,"about_ca_system_score_codex":0.0000144339965,"about_ca_system_score_gemma":0.000033867916,"threshold_uncertainty_score":0.3259131},"labels":[],"label_agreement":null},{"id":"W4389248538","doi":"10.1182/blood-2023-185007","title":"Non-Viral RNA-Lipid Nanoparticles for High Efficiency Genome Editing of CD34+ Hematopoietic Stem and Progenitor Cells for Advanced Cell and Gene Therapies","year":2023,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Precision Nanosystems (Canada)","funders":"","keywords":"Progenitor cell; Haematopoiesis; Stem cell; CD34; Biology; Cord blood; Gene delivery; Hematopoietic stem cell; Genetic enhancement; Cell biology; Molecular biology; Immunology; Gene; Genetics","score_opus":0.005069234897384554,"score_gpt":0.2347832497861119,"score_spread":0.22971401488872734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389248538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994703,0.0021761528,0.0024066265,0.000023053131,0.00011945533,0.0004881587,0.00006149786,0.000015820851,0.0000062470167],"genre_scores_gemma":[0.9957354,0.00021094616,0.0035729313,0.000008809532,0.00022724601,0.00011519193,0.000023242934,0.000025893996,0.00008031251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930865,0.000005803161,0.00017062406,0.00023613876,0.000054493416,0.00022428532],"domain_scores_gemma":[0.9997053,0.000024549334,0.000053019772,0.00012719113,0.00004287862,0.00004706129],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107343876,0.00011675173,0.00014468732,0.000029595856,0.00006392208,0.000013404622,0.00006763314,0.000060098653,4.889064e-7],"category_scores_gemma":[0.000008391638,0.0001111705,0.00004459114,0.000049255978,0.000038910865,0.0000028134289,0.000053183412,0.000020612713,3.820701e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023940798,0.000049485465,0.00016051362,0.00027561048,0.00002854757,4.1608791e-7,0.00021492396,0.00016967327,0.9981529,0.000008401487,0.000013137664,0.00090244797],"study_design_scores_gemma":[0.001583138,0.0004533791,0.00039260517,0.000011349188,0.000046654095,0.0000031957093,0.00028155805,0.00016901018,0.996634,0.000028262755,0.00026886057,0.00012799897],"about_ca_topic_score_codex":0.0000011068506,"about_ca_topic_score_gemma":8.582953e-7,"teacher_disagreement_score":0.0019652066,"about_ca_system_score_codex":0.0000015506524,"about_ca_system_score_gemma":0.000014198966,"threshold_uncertainty_score":0.45334014},"labels":[],"label_agreement":null},{"id":"W4389318264","doi":"10.5376/jmr.2023.13.0002","title":"The Method and Prospects of Changing Mosquito Genes with CRISPRCas9","year":2023,"lang":"en","type":"article","venue":"Journal of Mosquito Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Sustainability; Cas9; Gene drive; Human health; Balance of nature; Emerging technologies; Risk analysis (engineering); Biology; Computer science; Ecology; Business; Gene; Medicine; Genetics; Environmental health","score_opus":0.035427406313859475,"score_gpt":0.4321815550345206,"score_spread":0.3967541487206611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389318264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97891986,0.008297096,0.011417881,0.0008230657,0.00013622157,0.00018336008,0.0000028784289,0.00000512359,0.00021450143],"genre_scores_gemma":[0.992711,0.003558803,0.0026486774,0.000009037259,0.0004604143,0.000008682001,0.0000012651554,0.000022223128,0.0005798924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986973,0.00010696825,0.00022669703,0.00014357045,0.000464769,0.00036070187],"domain_scores_gemma":[0.999063,0.00013512596,0.0000812638,0.00022575307,0.0004027531,0.00009209919],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029695057,0.000084015024,0.00014322903,0.00019264419,0.00017493637,0.00004544482,0.00025665574,0.00006036807,0.0000023865764],"category_scores_gemma":[0.00024845163,0.00005182205,0.000050989293,0.00044595762,0.000107280015,0.0000045258603,0.00021675741,0.00020303752,0.0000011097976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001808116,0.00001796404,0.0012912011,0.00007680496,0.00010023678,0.000030226536,0.00031280596,0.0016082703,0.9652015,0.00012629367,0.0018676475,0.029186253],"study_design_scores_gemma":[0.0006293862,0.0012171777,0.00465865,0.00009952834,0.000020986721,0.00023500144,0.002012947,0.001085596,0.96796894,0.00024999309,0.021700097,0.00012171063],"about_ca_topic_score_codex":0.0000051788206,"about_ca_topic_score_gemma":0.000010249477,"teacher_disagreement_score":0.029064542,"about_ca_system_score_codex":0.000010387759,"about_ca_system_score_gemma":0.000080343634,"threshold_uncertainty_score":0.21132419},"labels":[],"label_agreement":null},{"id":"W4389323386","doi":"10.1021/acssynbio.3c00319","title":"<i>De Novo</i> Synthesis of a Conjugative System from Human Gut Metagenomic Data for Targeted Delivery of Cas9 Antimicrobials","year":2023,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Metagenomics; Computational biology; CRISPR; Biology; Contig; Plasmid; Cas9; Genetics; Escherichia coli; Citrobacter rodentium; Gene; Genome","score_opus":0.024490891694126198,"score_gpt":0.32582825837541685,"score_spread":0.30133736668129063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389323386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874566,0.0008692989,0.00654609,0.000045433302,0.00016181078,0.00030221645,0.004503315,0.000026890018,0.000088305635],"genre_scores_gemma":[0.9962084,0.00016070018,0.002272816,0.000024563724,0.00008965812,0.00003960593,0.0011364573,0.000032575208,0.000035208275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986655,0.0001102786,0.0004377715,0.0004522442,0.00004366648,0.00029050195],"domain_scores_gemma":[0.99859947,0.00025155125,0.00019096509,0.0008213973,0.0000910603,0.00004556443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004437255,0.00017533661,0.00045427657,0.000082475366,0.000048309863,0.000005313984,0.0005447847,0.00022938717,0.000012505802],"category_scores_gemma":[0.0002700999,0.00016891061,0.00010601611,0.000097477736,0.00017380717,0.000002558289,0.00030965192,0.0000484321,0.0000054503903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054331074,0.000025322703,0.00020589084,0.00012476256,0.00031324368,0.0000015501859,0.000056623456,0.0001458305,0.99756676,0.0001485215,0.0004767277,0.00088044594],"study_design_scores_gemma":[0.0003264288,0.00013251448,0.00036317104,0.000059586266,0.00017058686,0.000009585119,0.00022080075,0.00031949245,0.9952882,0.00005143946,0.0028879896,0.00017018769],"about_ca_topic_score_codex":0.00019899025,"about_ca_topic_score_gemma":0.000028929902,"teacher_disagreement_score":0.008751775,"about_ca_system_score_codex":0.000012752887,"about_ca_system_score_gemma":0.00006587421,"threshold_uncertainty_score":0.6887975},"labels":[],"label_agreement":null},{"id":"W4389333938","doi":"10.1038/s41467-023-43904-w","title":"Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada); Feldan (Canada)","funders":"California National Primate Research Center; National Institute of Diabetes and Digestive and Kidney Diseases; Howard Hughes Medical Institute; Roy J. Carver Charitable Trust; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Center for Research Resources; Québec Consortium for Drug Discovery; Institut sur la Nutrition et les Aliments Fonctionnels; National Institutes of Health; U.S. Department of Health and Human Services; National Institute of Environmental Health Sciences; Petroleum Technology Alliance Canada","keywords":"Ribonucleoprotein; Cystic fibrosis; Cell biology; Airway; Respiratory epithelium; In vivo; Biology; Peptide; Molecular biology; Epithelium; Chemistry; RNA; Medicine; Gene; Genetics; Biochemistry","score_opus":0.008324635655184398,"score_gpt":0.29710846818549635,"score_spread":0.288783832530312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389333938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9675,0.0045086304,0.0034894082,0.008009407,0.0055786357,0.0011177319,0.0010972003,0.000249724,0.008449288],"genre_scores_gemma":[0.992848,0.00092750974,0.0038967952,0.000291802,0.0006282186,0.000055936394,0.00017812567,0.000024774832,0.0011488427],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992963,0.00004302509,0.00014708725,0.00020525971,0.000098697456,0.00020964225],"domain_scores_gemma":[0.9986551,0.000051748,0.000022505616,0.0011125901,0.00006725382,0.00009082524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014830078,0.00011268569,0.000092613234,0.0001112167,0.00008819004,0.000015207959,0.0006418007,0.00022821975,0.000016304559],"category_scores_gemma":[0.00013200135,0.00012265975,0.00006091689,0.00033075694,0.00002830885,0.000002834148,0.00039249053,0.00031797087,0.00010096292],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013578365,0.00003908841,0.00032846813,0.0000065925474,0.000014326429,0.0000014763581,0.0001456216,0.0035252033,0.8303706,0.00007344427,0.1648288,0.0006527664],"study_design_scores_gemma":[0.00026512725,0.000049829672,0.0014029375,0.0000139520735,0.000008853553,0.0000012062947,0.00018921451,0.0011906611,0.294472,0.000010339607,0.702211,0.00018484153],"about_ca_topic_score_codex":0.000043585533,"about_ca_topic_score_gemma":0.0010052588,"teacher_disagreement_score":0.53738225,"about_ca_system_score_codex":0.000022280625,"about_ca_system_score_gemma":0.00004114764,"threshold_uncertainty_score":0.500192},"labels":[],"label_agreement":null},{"id":"W4389334714","doi":"10.1111/pbi.14232","title":"An integrated strategy involving high‐throughput sequencing to characterize an unknown GM wheat event in Canada","year":2023,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"Canadian Food Inspection Agency","keywords":"Biology; Sanger sequencing; Genome; Computational biology; Genetics; Transformation (genetics); Gene; Common wheat; DNA sequencing; Chromosome","score_opus":0.013760862877617162,"score_gpt":0.263132248080454,"score_spread":0.24937138520283683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389334714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952927,0.0002751338,0.0030996215,0.00064862106,0.00042194262,0.00011339727,0.00008514861,0.000055403554,0.000008029968],"genre_scores_gemma":[0.9979244,0.00066348806,0.00072474644,0.0001711518,0.00016287049,0.000009151666,0.0002931142,0.000027128306,0.00002393837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855393,0.000058753347,0.0003517149,0.00036302576,0.00013622007,0.0005363283],"domain_scores_gemma":[0.9993655,0.000009013691,0.000068137015,0.00031472679,0.000045764653,0.00019682308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028853692,0.00021074855,0.000219332,0.00026505487,0.000100937556,0.00004254122,0.0003850793,0.00029912114,0.00001511238],"category_scores_gemma":[0.00005189719,0.00020060064,0.000031495514,0.0003552998,0.00002702943,0.00001212694,0.00008586297,0.0004939704,0.0000052536993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003699051,0.00001674054,0.0013105316,0.000008523818,0.00002630621,0.0002740424,0.00005881193,0.012635098,0.97478455,0.00006877147,0.00031334592,0.010466256],"study_design_scores_gemma":[0.00069071166,0.0008577439,0.021982517,0.00012794569,0.000016148648,0.0013296084,0.002233032,0.009491966,0.9526935,0.00009911109,0.009865632,0.00061205536],"about_ca_topic_score_codex":0.10107372,"about_ca_topic_score_gemma":0.6098368,"teacher_disagreement_score":0.50876313,"about_ca_system_score_codex":0.00027098093,"about_ca_system_score_gemma":0.0007673563,"threshold_uncertainty_score":0.9049123},"labels":[],"label_agreement":null},{"id":"W4389375913","doi":"10.1177/19427786231215673","title":"CRISPR futures: Rethinking the politics of genome editing","year":2023,"lang":"en","type":"article","venue":"Human Geography","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Fundação para a Ciência e a Tecnologia","keywords":"Commercialization; Politics; Indigenous; Political science; Economic growth; Biology; Economics; Ecology; Law","score_opus":0.011090445513399359,"score_gpt":0.29070889420816926,"score_spread":0.27961844869476987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389375913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953723,0.0015572602,0.0011456345,0.000112823116,0.0002288188,0.00010565813,0.000017492643,0.000045074205,0.0014149356],"genre_scores_gemma":[0.9984535,0.00010968946,0.00016479693,0.00011071501,0.00086077827,0.000009710821,0.00009198641,0.000020357165,0.0001784511],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992428,0.000022190095,0.00017232154,0.00017589032,0.00012900497,0.00025781262],"domain_scores_gemma":[0.9995099,0.00001273283,0.000050259718,0.00033629488,0.000051127026,0.000039731174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021941778,0.000104061975,0.00009203213,0.00010139697,0.00024229138,0.000017251688,0.00022143096,0.00007934409,0.000014129545],"category_scores_gemma":[0.000026279955,0.00008572253,0.0001439578,0.00021452077,0.000089368485,0.0000012783114,0.00011369921,0.000097756165,0.000004048641],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000068038953,0.00003376593,0.018013593,0.00015636258,0.00021721273,0.0000073033953,0.0021660689,0.002570404,0.9660539,0.0031536287,0.0067833443,0.00083759567],"study_design_scores_gemma":[0.0011174115,0.0005954981,0.4736067,0.000112197034,0.0001651327,0.000028832119,0.0055809044,0.00032856237,0.34197956,0.010255801,0.16524172,0.0009877001],"about_ca_topic_score_codex":0.000020858408,"about_ca_topic_score_gemma":0.00001576309,"teacher_disagreement_score":0.62407434,"about_ca_system_score_codex":0.0000019501201,"about_ca_system_score_gemma":0.000008876124,"threshold_uncertainty_score":0.34956634},"labels":[],"label_agreement":null},{"id":"W4389390311","doi":"10.1016/j.xpro.2023.102706","title":"Protocol for replacing coding intronic MiMIC and CRIMIC lines with T2A-split-GAL4 lines in Drosophila using genetic crosses","year":2023,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Eye Institute; York University; New York University Shanghai","keywords":"Computational biology; Biology; Genotyping; Genetics; CRISPR; Protocol (science); Coding region; Gene; Genotype","score_opus":0.045596924376782616,"score_gpt":0.4038432643230325,"score_spread":0.3582463399462499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389390311","genre_codex":"empirical","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5417963,0.00002631625,0.005446727,0.000055818375,0.000024139283,0.45256144,0.000018680405,0.000055284985,0.000015288893],"genre_scores_gemma":[0.1124428,0.000005124961,0.013012249,0.000037122354,0.00032544314,0.8739876,0.000022777482,0.00007077268,0.0000961206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851984,0.000031738797,0.0003511098,0.0005287497,0.00011091595,0.00045767124],"domain_scores_gemma":[0.9993794,0.000029343282,0.00009295894,0.00033575774,0.00008963974,0.000072899355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026588494,0.00025640373,0.00024352483,0.00012364931,0.00012489861,0.00008834272,0.00014524812,0.00013206774,0.0000039152],"category_scores_gemma":[0.000103612736,0.00022976777,0.000051928568,0.00020644229,0.000080397025,0.00000871598,0.00011991661,0.000106149564,0.0000012824672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000715721,0.000050490315,0.0090672765,0.00163084,0.00003741436,0.000012195662,0.00019073597,0.013798764,0.9726997,0.000029739447,0.00017944684,0.0015876706],"study_design_scores_gemma":[0.009775594,0.0023368315,0.01786485,0.0017756218,0.000043762615,0.00011641538,0.00030864176,0.041813638,0.897756,0.0006223728,0.026297787,0.0012884898],"about_ca_topic_score_codex":0.000022983673,"about_ca_topic_score_gemma":0.00007317642,"teacher_disagreement_score":0.4293535,"about_ca_system_score_codex":0.000026344029,"about_ca_system_score_gemma":0.00013173919,"threshold_uncertainty_score":0.93696576},"labels":[],"label_agreement":null},{"id":"W4389398607","doi":"10.1038/s41467-023-43041-4","title":"Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Common Fund; National Institute on Drug Abuse; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Medical Research Council; Versus Arthritis; Diabetes UK; Department of Health and Social Care; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; NIH Office of the Director; Cancer Research UK; Academy of Medical Sciences; National Human Genome Research Institute; Wellcome Trust; National Cancer Institute; British Heart Foundation; National Institutes of Health; Wellcome","keywords":"Germline; Somatic cell; Genetics; Genome; Germline mutation; Biology; Pathogenicity; Saturation (graph theory); Computational biology; Mutation; Gene; Microbiology","score_opus":0.010009059650892623,"score_gpt":0.3103266341989091,"score_spread":0.3003175745480165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389398607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893912,0.0046896613,0.0048631094,0.000527712,0.000081005484,0.00014435315,0.000055680885,0.000019553836,0.00022770096],"genre_scores_gemma":[0.99323094,0.0010396079,0.0052292775,0.000020133513,0.000054268676,0.000008479206,0.00038641976,0.0000072513294,0.000023628696],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995697,0.000036984053,0.00018053199,0.00008633143,0.00006285528,0.00006358272],"domain_scores_gemma":[0.99923974,0.000041183946,0.00008949247,0.00051072496,0.00010205738,0.000016775206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018965085,0.00005467399,0.00008349211,0.00005315332,0.000054555647,0.000004882723,0.00017332676,0.00016258429,0.0000013861019],"category_scores_gemma":[0.00020531287,0.0000563847,0.00003189584,0.00015270115,0.000043097887,0.0000032946587,0.00015196198,0.00013685176,5.021152e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003006512,0.000015452135,0.0013652929,0.000037979687,0.000018847424,4.4414186e-8,0.00021435368,0.0003035596,0.9967809,0.00066562736,0.00007210723,0.00052288413],"study_design_scores_gemma":[0.0004598384,0.000106948486,0.7085294,0.000049740254,0.000079925325,0.000007976325,0.00038787708,0.010379346,0.27359805,0.0005321257,0.0056557287,0.00021299663],"about_ca_topic_score_codex":0.0000058784485,"about_ca_topic_score_gemma":0.000049578448,"teacher_disagreement_score":0.7231828,"about_ca_system_score_codex":0.0000034017596,"about_ca_system_score_gemma":0.000016739463,"threshold_uncertainty_score":0.22993013},"labels":[],"label_agreement":null},{"id":"W4389451094","doi":"10.1212/wnl.80.7_supplement.s13.002","title":"Autosomal-Dominant Parkinsonism Associated with a Newly Described Mutation in DNAJC13: Clinical, Imaging and Pathological Description (S13.002)","year":2013,"lang":"en","type":"article","venue":"Neurology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Sport Centre Pacific; University of Saskatchewan; University of British Columbia","funders":"","keywords":"Parkinsonism; Asymptomatic; Pathological; Dopaminergic; Levodopa; Medicine; Asymptomatic carrier; Parkinson's disease; Internal medicine; Family history; Neurological examination; Disease; Gastroenterology; Pediatrics; Pathology; Psychology; Surgery; Dopamine","score_opus":0.012984277182414149,"score_gpt":0.2758889103209903,"score_spread":0.26290463313857615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389451094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99132013,0.00028644365,0.0074257297,0.00047453618,0.00013983621,0.00024584495,0.000002348055,0.00002194891,0.00008317649],"genre_scores_gemma":[0.99797815,0.00012775125,0.00079230004,0.0008977956,0.00006630963,0.000054310476,0.000036213834,0.000020048925,0.000027144117],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99873847,0.00019137464,0.0002846934,0.00042271946,0.000066865556,0.00029587597],"domain_scores_gemma":[0.99958134,0.000050338702,0.00007699818,0.00016502962,0.000051382707,0.00007494301],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002337163,0.00015209883,0.00019491625,0.000053671807,0.000044303477,0.000030755153,0.00008114412,0.0001978984,0.000010070192],"category_scores_gemma":[0.00022881747,0.00013097061,0.000037733527,0.00007416852,0.00012523332,0.000008491649,0.00006327017,0.00020252903,0.00000528032],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034164582,0.00021288589,0.46407577,0.000011730734,0.000032588192,0.00021830325,0.00016643634,0.00082500384,0.5150265,0.000025535226,0.0004198302,0.018643742],"study_design_scores_gemma":[0.0020942276,0.0012930739,0.98074996,0.000010269331,0.000020509964,0.0002098488,0.000029128829,0.008263997,0.0057349177,0.0001363008,0.0012410238,0.00021672936],"about_ca_topic_score_codex":0.00007158379,"about_ca_topic_score_gemma":0.00015482427,"teacher_disagreement_score":0.5166742,"about_ca_system_score_codex":0.0000061597907,"about_ca_system_score_gemma":0.000023441069,"threshold_uncertainty_score":0.53408265},"labels":[],"label_agreement":null},{"id":"W4389484646","doi":"10.1016/j.isci.2023.108693","title":"Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein","year":2023,"lang":"en","type":"article","venue":"iScience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; University of Alberta; JDRF; National Institute of Diabetes and Digestive and Kidney Diseases; Stanford Diabetes Research Center; Wellcome Trust; Juvenile Diabetes Research Foundation United States of America","keywords":"CRISPR; Genome editing; Ribonucleoprotein; Cas9; Biology; Human genome; Gene; Guide RNA; Computational biology; Electroporation; RNA; DNA; Genetics; Genome; Cell biology","score_opus":0.008611692295288435,"score_gpt":0.2760805612757267,"score_spread":0.2674688689804383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389484646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99665856,0.00014907235,0.0020799795,0.00007234513,0.00011596035,0.00015609073,0.000008551204,0.000033552285,0.0007258642],"genre_scores_gemma":[0.99655396,0.000019362778,0.0026450434,0.00008746832,0.00017492483,0.000023028446,0.000027646962,0.00001627123,0.00045228898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900705,0.00001449109,0.00013516864,0.000353549,0.00015898321,0.00033075907],"domain_scores_gemma":[0.99962604,0.0000067785854,0.00003135737,0.00025020415,0.000026657539,0.00005895245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023359859,0.00011251868,0.000094261,0.00007380651,0.00008974311,0.00002684846,0.00020853757,0.00005702237,0.0000065252257],"category_scores_gemma":[0.00002487002,0.00010309293,0.000025974507,0.00032807153,0.000082829465,0.000004915877,0.00012724106,0.00007854957,0.000017675296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000051006327,0.000012152845,0.0013560012,0.000014568123,0.000002263063,0.000021599755,0.00010206693,0.004971588,0.99202794,0.000004243097,0.00043371116,0.0010487462],"study_design_scores_gemma":[0.0003312631,0.000099904544,0.018567441,0.00001951919,0.0000022308402,0.0000090028925,0.00009834618,0.0008028431,0.97773576,0.0000080354275,0.002162324,0.00016334448],"about_ca_topic_score_codex":0.00006429741,"about_ca_topic_score_gemma":0.000104026454,"teacher_disagreement_score":0.017211441,"about_ca_system_score_codex":0.000014240617,"about_ca_system_score_gemma":0.000032591783,"threshold_uncertainty_score":0.42040074},"labels":[],"label_agreement":null},{"id":"W4389486522","doi":"10.1089/hum.2023.114","title":"Multidimensional Response Surface Methodology for the Development of a Gene Editing Protocol for p67 <sup>phox</sup> -Deficient Chronic Granulomatous Disease","year":2023,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Wellcome Trust; Great Ormond Street Hospital for Children; National Institute for Health and Care Research; University College London; LifeArc","keywords":"Chronic granulomatous disease; Genetic enhancement; Gene; Disease; Genome editing; Protocol (science); Biology; Computational biology; Medicine; Immunology; Genetics; Pathology; CRISPR","score_opus":0.07826308621544252,"score_gpt":0.40503624679963723,"score_spread":0.3267731605841947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389486522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88782144,0.0005278019,0.082486756,0.000096232354,0.00008000844,0.028890563,0.00005800559,0.000036469784,0.0000027310396],"genre_scores_gemma":[0.70962733,0.000050297305,0.11879429,0.00017383705,0.0009729577,0.16892947,0.0004734884,0.00018155592,0.0007967577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858046,0.00012592023,0.00037572204,0.0003793512,0.00015312964,0.00038540823],"domain_scores_gemma":[0.99905837,0.00024183016,0.00010576658,0.00038519283,0.00012893035,0.00007990782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013430142,0.00021033264,0.00020178691,0.00005455778,0.00031489067,0.000010781383,0.00021977103,0.00008801844,0.000016092847],"category_scores_gemma":[0.00010304338,0.00016448469,0.00016999905,0.00009819574,0.000068985915,0.0000018924206,0.000071338814,0.000051778617,0.0000026278472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018139324,0.00005924668,0.00004655605,0.00008019823,0.00009829862,0.0000010261822,0.00056629174,0.046114948,0.9479195,0.00002342087,0.0006306825,0.0026459186],"study_design_scores_gemma":[0.0029351898,0.0004757785,0.0023081368,0.000019536288,0.000015074386,0.0000035775429,0.00013355412,0.006090172,0.9369689,0.000042621217,0.0507986,0.00020884188],"about_ca_topic_score_codex":0.0000023696289,"about_ca_topic_score_gemma":0.0000067778315,"teacher_disagreement_score":0.17819409,"about_ca_system_score_codex":0.00002376332,"about_ca_system_score_gemma":0.00023693027,"threshold_uncertainty_score":0.6707491},"labels":[],"label_agreement":null},{"id":"W4389569968","doi":"10.1101/2023.12.10.570953","title":"Highly efficient transgenic mouse production using piggyBac and its application to rapid phenotyping at the founder generation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Kanazawa University; Kindai University","keywords":"Transgene; Microinjection; Biology; Transposable element; Genetically modified mouse; Phenotype; First generation; Fourth generation; Genetics; Genetically modified organism; Genome; Computational biology; Cell biology; Gene; Third generation; Computer science; Population; Medicine","score_opus":0.02058368063948912,"score_gpt":0.2598149044445046,"score_spread":0.2392312238050155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389569968","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90694916,0.0018955143,0.08884119,0.00029568517,0.0007982177,0.0010780526,0.000045361852,0.00009621242,5.938412e-7],"genre_scores_gemma":[0.9968702,0.00040072898,0.001138903,0.000085418826,0.001093595,0.0002640451,0.000004116647,0.00011593057,0.000027014145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981186,0.00006817405,0.00031517254,0.0009587973,0.00020633814,0.00033294669],"domain_scores_gemma":[0.9987299,0.000008869945,0.00012670252,0.00079221674,0.00021567436,0.00012662602],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045607932,0.00034075658,0.00020886149,0.00010866797,0.00026983762,0.00008507147,0.0002124198,0.00029326652,0.0000029707455],"category_scores_gemma":[0.00008715438,0.00033171984,0.00008231384,0.0002333955,0.00003735602,0.0000046939335,0.00033567264,0.00020391762,0.000017908398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017430359,0.000019432795,0.00006688285,0.00010786743,0.00006301642,3.1192042e-7,0.000017817407,0.10191387,0.897677,0.000017788258,0.000088529814,0.000010040613],"study_design_scores_gemma":[0.000156341,0.000027406762,0.0020531036,0.000041581483,0.00006899342,3.517948e-8,0.0000034964673,0.019440994,0.9760263,2.0386378e-7,0.0017843699,0.0003972009],"about_ca_topic_score_codex":0.00001735881,"about_ca_topic_score_gemma":0.000016390739,"teacher_disagreement_score":0.08992107,"about_ca_system_score_codex":0.0001302807,"about_ca_system_score_gemma":0.00011385261,"threshold_uncertainty_score":0.9999135},"labels":[],"label_agreement":null},{"id":"W4389730198","doi":"10.1007/978-3-031-46150-7_25","title":"Genome Editing in Biotech Regulations Worldwide","year":2023,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung; European Commission","keywords":"Legislation; Legislature; De facto; Product (mathematics); Genome; Political science; Biotechnology; Biology; International trade; Business; Law; Genetics; Gene","score_opus":0.01207860077979504,"score_gpt":0.2693067714449207,"score_spread":0.25722817066512565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389730198","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001442658,0.0015648283,0.009304093,0.00039415128,0.00069042697,0.0003996429,0.00006999474,0.00013055188,0.98600364],"genre_scores_gemma":[0.023098521,0.00046940643,0.0009643559,0.00005769777,0.00093785673,0.000012068717,0.0006015839,0.00010051796,0.973758],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991557,0.0000032253633,0.00022934805,0.00032911022,0.00009256816,0.00019006472],"domain_scores_gemma":[0.99955744,0.000008832742,0.000042291173,0.00031765187,0.000027211623,0.000046594418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009520626,0.00018944866,0.00015216818,0.00015106266,0.0000270422,0.000013732261,0.00012547802,0.00033540613,0.0001402797],"category_scores_gemma":[0.000023514494,0.0002076487,0.00009061018,0.000037087724,0.000024561534,6.8747863e-7,0.00012446605,0.00016320562,0.000086626846],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035257635,0.000038459308,0.00023535997,0.00029511808,0.0003924365,0.00011343537,0.00013498607,0.01865901,0.8993096,0.045596108,0.015725467,0.0194648],"study_design_scores_gemma":[0.00034980028,0.00007435291,0.001942265,0.00014255056,0.000033530934,0.00001529755,0.00003050884,0.00021219793,0.018827733,0.0029918917,0.97458184,0.00079802336],"about_ca_topic_score_codex":0.0000095618725,"about_ca_topic_score_gemma":0.0003262335,"teacher_disagreement_score":0.9588564,"about_ca_system_score_codex":0.000016259917,"about_ca_system_score_gemma":0.00002885553,"threshold_uncertainty_score":0.8467668},"labels":[],"label_agreement":null},{"id":"W4389794524","doi":"10.1038/s41467-023-43602-7","title":"Essential transcription factors for induced neuron differentiation","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Human Genome Research Institute; National Cancer Institute; U.S. Department of Health and Human Services; Advanced Research Projects Agency; National Institutes of Health; York University; New York Genome Center","keywords":"Biology; Transcription factor; Induced pluripotent stem cell; Neurite; Cellular differentiation; Cell biology; CRISPR; Chromatin; Computational biology; Regulation of gene expression; Gene; Embryonic stem cell; Genetics; In vitro","score_opus":0.0221343988238909,"score_gpt":0.3397924210671199,"score_spread":0.317658022243229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389794524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895774,0.00047398394,0.008502618,0.00066146324,0.00035791713,0.00023224867,0.000037169586,0.000058783175,0.00009842697],"genre_scores_gemma":[0.99702084,0.0002938427,0.0004288768,0.000044154276,0.00008790642,0.00005237003,0.00193345,0.00001653801,0.000122048594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995912,0.000023769904,0.00009583615,0.00012661352,0.00005421085,0.00010839743],"domain_scores_gemma":[0.9993115,0.000028380598,0.000024568244,0.0005552958,0.000052737814,0.000027527722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005610983,0.00007384024,0.00005458508,0.000052347965,0.00012595156,0.000016245027,0.00027790546,0.00018641425,0.000002119659],"category_scores_gemma":[0.00008248953,0.000075223565,0.000069820686,0.0001248712,0.000014251206,0.0000027251895,0.000063136664,0.00014993535,0.0000027064987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000062600952,0.00001958048,0.00061123486,0.00000698049,0.000015587128,1.9508e-8,0.0000748564,0.000067853485,0.99684024,0.00039553148,0.0014336337,0.00052823126],"study_design_scores_gemma":[0.0005883077,0.00012274501,0.1587187,0.00000912396,0.00005372263,0.0000011210384,0.00018338102,0.0037410688,0.76241255,0.00013464304,0.07377737,0.0002572375],"about_ca_topic_score_codex":0.0000029573707,"about_ca_topic_score_gemma":0.000097293,"teacher_disagreement_score":0.23442766,"about_ca_system_score_codex":0.0000055066807,"about_ca_system_score_gemma":0.000012809324,"threshold_uncertainty_score":0.3067528},"labels":[],"label_agreement":null},{"id":"W4389834824","doi":"10.7860/jcdr/2023/68275.18809","title":"A Scoping Review on the Ethical Issues in the Use of CRISPR-Cas9 in the Creation of Human Disease Models","year":2023,"lang":"en","type":"review","venue":"JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Cas9; Disease; Computer science; Pace; Genome editing; Engineering ethics; Data science; Medicine; Biology; Genetics; Engineering; Gene; Pathology; Geography","score_opus":0.5571806117843385,"score_gpt":0.6441158101017248,"score_spread":0.08693519831738628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389834824","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0025630032,0.9936261,0.000059893708,0.002717025,0.000040938252,0.00095114147,0.0000106175285,5.4027277e-7,0.00003074755],"genre_scores_gemma":[0.007311023,0.9920973,0.000017675882,0.0002344967,0.00024472285,0.00005398035,0.000008750814,0.000012207037,0.00001984094],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.9946193,0.002789955,0.0015855103,0.00018194695,0.00064784166,0.00017542952],"domain_scores_gemma":[0.979766,0.019191457,0.0003493892,0.00041689933,0.00020783993,0.00006840786],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.012985304,0.0001339128,0.00087926426,0.000111874884,0.000045514225,0.000034482036,0.000527983,0.0002399283,0.0000051510433],"category_scores_gemma":[0.040006146,0.000057348596,0.00036049573,0.00031238009,0.0002796765,0.0000045905517,0.00012839105,0.0014749996,9.200934e-7],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006357217,0.0027253546,0.0028904192,0.33063418,0.0006959834,0.0007097847,0.0011449929,0.0019249319,0.000038252707,0.008258671,0.04754879,0.6027929],"study_design_scores_gemma":[0.0009396713,0.0025059911,0.004256395,0.84068954,0.0006630149,0.000042940264,0.00024361083,0.00017497035,0.000027452366,0.0034679396,0.1466461,0.0003424035],"about_ca_topic_score_codex":0.000029552302,"about_ca_topic_score_gemma":0.000035710218,"teacher_disagreement_score":0.6024505,"about_ca_system_score_codex":0.000004569958,"about_ca_system_score_gemma":0.00027690202,"threshold_uncertainty_score":0.9680803},"labels":[],"label_agreement":null},{"id":"W4389938563","doi":"10.3389/fgeed.2023.1265103","title":"Diversity of transgene integration and gene-editing events in wheat (Triticum aestivum L.) transgenic plants generated using Agrobacterium-mediated transformation","year":2023,"lang":"en","type":"article","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Saskatchewan Wheat Development Commission; Alberta Wheat Commission; Western Grains Research Foundation","keywords":"Biology; Transformation (genetics); Transgene; Genome editing; Population; Genetics; Agrobacterium; Gene; Genetically modified crops; Transformation efficiency; CRISPR; Epigenetics; Computational biology","score_opus":0.011895977776303848,"score_gpt":0.2486014207065623,"score_spread":0.23670544293025844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389938563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9038094,0.00043514097,0.094747566,0.000026326976,0.0006286931,0.00024046651,0.0000813978,0.000018806206,0.000012179643],"genre_scores_gemma":[0.9965285,0.0004298048,0.002147994,0.000011179931,0.00021958663,0.000009961117,0.0006259244,0.000021498601,0.0000055231676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875414,0.00006462141,0.00041039774,0.00028518873,0.00014979177,0.0003358721],"domain_scores_gemma":[0.9997094,0.000011820445,0.00007298118,0.00010323617,0.000039895982,0.00006264845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038060755,0.00017573882,0.00023902942,0.00031536832,0.00012249665,0.0000057120133,0.00011174088,0.00017186094,0.000002400408],"category_scores_gemma":[0.000042334297,0.0002069902,0.000053360713,0.0003482076,0.00003624097,0.000023731296,0.000059852562,0.00013449746,4.1705104e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048697737,0.000021577425,0.039187383,0.00009315502,0.00002768055,0.000004535266,0.0023687242,0.016023422,0.9410536,4.6251472e-7,0.0000146160455,0.0011561258],"study_design_scores_gemma":[0.003207923,0.0001736404,0.31008375,0.0002516123,0.00005151207,0.000019161425,0.0042391815,0.09828385,0.58298224,0.000039750546,0.00010178229,0.00056556414],"about_ca_topic_score_codex":0.00006329788,"about_ca_topic_score_gemma":0.00010995996,"teacher_disagreement_score":0.35807136,"about_ca_system_score_codex":0.00004979616,"about_ca_system_score_gemma":0.000030421543,"threshold_uncertainty_score":0.8440815},"labels":[],"label_agreement":null},{"id":"W4390106146","doi":"10.3390/cells13010031","title":"Successful Correction by Prime Editing of a Mutation in the RYR1 Gene Responsible for a Myopathy","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; RYR-1 Foundation","keywords":"RYR1; Mutation; Point mutation; Gene; Genetics; Myopathy; Genome editing; Biology; Ryanodine receptor; Gene mutation; CRISPR; Receptor","score_opus":0.006347292387806518,"score_gpt":0.286491673056758,"score_spread":0.2801443806689515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390106146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97674733,0.00023573624,0.022257946,0.00006370935,0.0003595713,0.00019415443,0.00001708877,0.00000823514,0.00011622925],"genre_scores_gemma":[0.9990498,0.00004306534,0.0002685734,0.000027642904,0.00013010629,0.00003638208,0.00011997524,0.000008718835,0.00031576265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99960923,0.000022240645,0.00010583179,0.0001093279,0.000050460196,0.00010290802],"domain_scores_gemma":[0.99979204,0.000036080994,0.00003177376,0.000103177845,0.000026081607,0.00001083409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026380917,0.000047453104,0.00005107773,0.00003601972,0.000021997519,0.000006798764,0.00006664838,0.000046849007,0.000002039799],"category_scores_gemma":[0.00006432048,0.000041849784,0.00003056789,0.00013173118,0.000010769518,0.000001317091,0.000015303813,0.000028149248,0.0000022253473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023288852,0.000010664395,0.0001532133,0.000012914734,0.000003483319,8.239873e-7,0.00019323899,0.0013711507,0.98959106,0.0000014975195,0.0069418815,0.0016967889],"study_design_scores_gemma":[0.00020198894,0.00010185875,0.00063926814,0.0000071719587,0.000004752089,0.0000029642101,0.00047013868,0.0028933843,0.9927307,0.000016766524,0.0028856858,0.000045358527],"about_ca_topic_score_codex":0.0000135437695,"about_ca_topic_score_gemma":0.000012908687,"teacher_disagreement_score":0.022302445,"about_ca_system_score_codex":0.000004052421,"about_ca_system_score_gemma":0.000018793997,"threshold_uncertainty_score":0.17065845},"labels":[],"label_agreement":null},{"id":"W4390166548","doi":"10.1101/2023.12.23.573214","title":"Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; University of California, Los Angeles; National Institutes of Health","keywords":"Crosstalk; Genomics; Mechanism (biology); Computational biology; Biology; Genetics; Computer science; Genome; Engineering; Gene; Physics; Electronic engineering","score_opus":0.012047271350952522,"score_gpt":0.23542345160074815,"score_spread":0.22337618024979564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390166548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94827455,0.0041465526,0.04391146,0.000012162643,0.0006897397,0.0004579158,0.0024676216,0.000037666574,0.000002316884],"genre_scores_gemma":[0.9915308,0.0015791622,0.006443748,0.000018353005,0.00022988612,0.000051467738,0.000010053108,0.00012648682,0.000010043242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977165,0.00007443548,0.0007620131,0.0006759582,0.00034253273,0.00042856377],"domain_scores_gemma":[0.9979398,0.000022119888,0.0004918116,0.00092204637,0.0004951717,0.0001290237],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040083777,0.0004266161,0.00066523906,0.00020217474,0.00004806046,0.00001861518,0.0004936212,0.00061734224,0.000025106308],"category_scores_gemma":[0.000072954615,0.0005004428,0.0003317357,0.00017029625,0.000118747936,0.0000049492833,0.00039253265,0.00023624727,0.0000022188117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006286551,0.00010138208,0.0026296994,0.0010345257,0.0003129917,0.000008122143,0.000018957853,0.0017392007,0.99385035,0.00018337894,0.000056854824,0.0000016467505],"study_design_scores_gemma":[0.0005551843,0.00011919418,0.058121137,0.00019193093,0.00013514292,3.9215664e-8,0.000009368999,0.00041548922,0.9395991,0.000009656658,0.00044146532,0.00040227012],"about_ca_topic_score_codex":0.00014426539,"about_ca_topic_score_gemma":0.000022681039,"teacher_disagreement_score":0.055491436,"about_ca_system_score_codex":0.000044013806,"about_ca_system_score_gemma":0.00045528484,"threshold_uncertainty_score":0.9997447},"labels":[],"label_agreement":null},{"id":"W4390348141","doi":"10.1002/cpz1.965","title":"Production of CRISPR‐Cas9 Transgenic Cell Lines for Knocksideways Studies","year":2023,"lang":"en","type":"article","venue":"Current Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; University of Washington; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Context (archaeology); Synthetic biology; Computational biology; Green fluorescent protein; Transgene; Genome editing; Cas9; Biology; Computer science; Gene; Genetics","score_opus":0.08593432879648592,"score_gpt":0.45444643934458995,"score_spread":0.368512110548104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390348141","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75724465,0.012123907,0.0531047,0.00045957364,0.003047751,0.17348166,0.00013005087,0.00024283554,0.00016484727],"genre_scores_gemma":[0.7708696,0.0012968424,0.0015671855,0.000013762982,0.0016202445,0.22267607,0.00018845487,0.00007560175,0.0016922391],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992012,0.000014917393,0.00023516944,0.00026734165,0.000092422146,0.0001889853],"domain_scores_gemma":[0.9994848,0.00001155676,0.00005837523,0.00023907248,0.00017350723,0.00003269982],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020401852,0.00012385215,0.0001560454,0.000053309926,0.000044996552,0.00000649788,0.00010984192,0.000057625643,0.0000023224256],"category_scores_gemma":[0.0001224375,0.00011323569,0.00011419806,0.00013622081,0.000034919034,0.0000026612952,0.00004184528,0.000047829726,0.0000047424774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006879215,0.00007817797,0.00028639598,0.0016310215,0.000037802827,1.1561801e-7,0.00018274949,0.001014706,0.96737534,0.000015537837,0.015193248,0.014116089],"study_design_scores_gemma":[0.0004043424,0.00023747492,0.00021965805,0.00008258122,0.000016331178,6.310383e-7,0.00009237039,0.000058403533,0.86673754,0.00009375549,0.1319405,0.000116400864],"about_ca_topic_score_codex":2.9680382e-7,"about_ca_topic_score_gemma":0.0000024925469,"teacher_disagreement_score":0.116747245,"about_ca_system_score_codex":0.0000052988353,"about_ca_system_score_gemma":0.00003614044,"threshold_uncertainty_score":0.46176177},"labels":[],"label_agreement":null},{"id":"W4390374444","doi":"10.1016/j.celrep.2023.113615","title":"Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Terry Fox Research Institute; Fondation du cancer du sein du Québec; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Faculty of Medicine, McGill University; McGill University; Chicago Community Trust","keywords":"Embryonic stem cell; Phosphorylation; Cell biology; Posttranslational modification; Stem cell; Biology; Genetics; Biochemistry; Gene; Enzyme","score_opus":0.00896999736838067,"score_gpt":0.2642976396369447,"score_spread":0.255327642268564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390374444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981603,0.00025949755,0.0003899876,0.000013791123,0.000076730554,0.000099435914,0.0000111854615,0.0000074074865,0.0009816597],"genre_scores_gemma":[0.99839544,0.00007061796,0.000019986943,0.0000036408578,0.000029516134,0.000004087675,0.000048345537,0.000011221321,0.0014171199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994843,0.000011145982,0.00017895001,0.00012652458,0.00010792418,0.00009117967],"domain_scores_gemma":[0.9995816,0.00001807219,0.00009454842,0.00024373534,0.000038899674,0.000023144563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014713507,0.000069869275,0.00008010122,0.000029759565,0.000016920387,0.0000030650021,0.000045091267,0.000055024655,0.000029472043],"category_scores_gemma":[0.0000068892837,0.000050716724,0.00011323877,0.00009126375,0.000015788608,9.247284e-7,0.000013349957,0.000034821776,0.0000028279137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015912276,0.000021369238,0.0046510105,0.000018209796,0.00002265934,0.0000033684578,0.000048590075,0.03768127,0.9555185,0.000004718379,0.0016887296,0.00032567157],"study_design_scores_gemma":[0.00008729441,0.00010950012,0.01474997,0.0000057528932,0.000008434272,0.0000040056348,0.00002438942,0.00060064817,0.9839037,0.000011986985,0.00043985824,0.000054427124],"about_ca_topic_score_codex":0.0000054827324,"about_ca_topic_score_gemma":0.0000014116154,"teacher_disagreement_score":0.037080623,"about_ca_system_score_codex":0.0000030456108,"about_ca_system_score_gemma":0.00004569938,"threshold_uncertainty_score":0.2068168},"labels":[],"label_agreement":null},{"id":"W4390401714","doi":"10.1016/j.csbj.2023.12.036","title":"Combining Off‐flow, a Nextflow‐coded program, and whole genome sequencing reveals unintended genetic variation in CRISPR/Cas-edited iPSCs","year":2023,"lang":"en","type":"article","venue":"Computational and Structural Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Hospital for Sick Children; McLaughlin Centre, University of Toronto; University of Toronto; Canada Foundation for Innovation; Sick Kids Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Autism Speaks","keywords":"CRISPR; Biology; Sanger sequencing; Genetics; Genome editing; Locus (genetics); Computational biology; Genome; Induced pluripotent stem cell; Genomics; Human genome; DNA sequencing; Gene; Embryonic stem cell","score_opus":0.010066671104853759,"score_gpt":0.28034658453640626,"score_spread":0.2702799134315525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390401714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9780782,0.0013349303,0.018376557,0.001783365,0.00016626944,0.00017223696,0.000020736128,0.000062181316,0.000005549701],"genre_scores_gemma":[0.9796678,0.00043780642,0.019503418,0.00008459356,0.00011996883,0.000008826076,0.00013976464,0.000015882295,0.000021969017],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99890727,0.00004488618,0.00033008997,0.00030236426,0.000119949065,0.0002954565],"domain_scores_gemma":[0.9996092,0.000023214956,0.00009586323,0.00009905163,0.00008739307,0.00008529374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017952723,0.00017287442,0.00018698511,0.0002759142,0.00020656329,0.00006775918,0.00012182825,0.00026301324,0.0000039277343],"category_scores_gemma":[0.00008911155,0.00016338014,0.000038424016,0.00029776397,0.00015067052,0.000011050945,0.0001313255,0.0003161309,0.0000015678756],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060091756,0.000011685602,0.0028207013,0.00004285312,0.00009971846,0.00008487316,0.00051001535,0.108514674,0.83384705,0.00034831814,0.000109227345,0.053550787],"study_design_scores_gemma":[0.0022194867,0.0006393133,0.46679,0.000073559844,0.000039750594,0.0028026518,0.0004763549,0.49617636,0.005210617,0.023808327,0.0012303204,0.00053326925],"about_ca_topic_score_codex":0.000005702449,"about_ca_topic_score_gemma":0.000009406258,"teacher_disagreement_score":0.8286364,"about_ca_system_score_codex":0.0000393725,"about_ca_system_score_gemma":0.000053336,"threshold_uncertainty_score":0.66624486},"labels":[],"label_agreement":null},{"id":"W4390534652","doi":"10.1007/s13237-023-00462-2","title":"A birds-eye-view on CRISPR-Cas system in agriculture","year":2024,"lang":"en","type":"article","venue":"The Nucleus","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"CRISPR; Genome editing; Agriculture; Translational research; Biotechnology; Biology; Computer science; Genetics; Ecology; Gene","score_opus":0.0061054903503350655,"score_gpt":0.2781050213438199,"score_spread":0.27199953099348484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390534652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96505886,0.018319188,0.0019445051,0.0010833903,0.0010699816,0.00040407956,0.000033729364,0.0001609416,0.0119253015],"genre_scores_gemma":[0.99838877,0.00023639042,0.000055817778,0.0001316815,0.00031242994,0.000018869452,0.000009719681,0.000022456043,0.00082384754],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99940753,0.000025289251,0.00011371242,0.00020522483,0.000080366066,0.00016785723],"domain_scores_gemma":[0.99969155,0.000009193355,0.000010209921,0.00024406015,0.0000116548235,0.00003331228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001249397,0.00011482781,0.00008861403,0.000026036229,0.00003276977,0.00003953864,0.00015558625,0.00008309482,0.000008973355],"category_scores_gemma":[0.00001213014,0.00007006307,0.00006513108,0.00012304318,0.000016165464,0.0000011375251,0.00005074808,0.00011845982,0.00011170291],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050656025,0.00006039766,0.00017210048,0.00052311155,0.00011277596,0.00010481384,0.0007102052,0.0035619114,0.9401705,0.0038501061,0.030422587,0.020260835],"study_design_scores_gemma":[0.00032075364,0.00022670861,0.0039496245,0.0004279811,0.000040952407,0.0000902568,0.0005291888,0.0014329166,0.24132504,0.0000451013,0.7512655,0.00034595293],"about_ca_topic_score_codex":0.000025312738,"about_ca_topic_score_gemma":0.000028998327,"teacher_disagreement_score":0.72084296,"about_ca_system_score_codex":0.000021967191,"about_ca_system_score_gemma":0.000013030374,"threshold_uncertainty_score":0.2857089},"labels":[],"label_agreement":null},{"id":"W4390618247","doi":"10.1093/nar/gkad1247","title":"Intein-based thermoregulated meganucleases for containment of genetic material","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Intein; Biology; Plasmid; Homing endonuclease; Escherichia coli; Endonuclease; Synthetic biology; Mutagenesis; DNA; Genetics; Computational biology; Gene; Mutation; RNA splicing","score_opus":0.02108437209951899,"score_gpt":0.3628113965056464,"score_spread":0.34172702440612746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390618247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98618543,0.0013195857,0.011284961,0.00015246084,0.00020246823,0.00042756918,0.00008768614,0.00002715757,0.00031266664],"genre_scores_gemma":[0.99743295,0.000047831712,0.0017520463,0.000022176331,0.00023790459,0.00006660527,0.00006887436,0.00004745974,0.000324182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988927,0.000053182346,0.00019875588,0.00029993418,0.00024006034,0.00031531818],"domain_scores_gemma":[0.9994241,0.000045060377,0.0000139762,0.00030303132,0.00014042252,0.00007343205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035841452,0.00011283573,0.000124799,0.000108551125,0.000051627576,0.000046630284,0.00021643913,0.000114598384,0.00016943376],"category_scores_gemma":[0.00008428546,0.000101369405,0.00009768569,0.00013252904,0.00013386464,0.0000016760569,0.000088868925,0.000083590356,0.000009030471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023203884,0.00003676948,0.000096676136,0.00019905779,0.000058886584,0.000004970946,0.000045022458,0.00037957355,0.9854215,0.00015364593,0.0024678963,0.010904006],"study_design_scores_gemma":[0.00039812608,0.0007430158,0.001808732,0.00006682158,0.000014588226,0.000004355003,0.000079630576,0.0075000133,0.9532548,0.00013118635,0.035870306,0.0001284253],"about_ca_topic_score_codex":0.000019233117,"about_ca_topic_score_gemma":0.000004767123,"teacher_disagreement_score":0.03340241,"about_ca_system_score_codex":0.000025447196,"about_ca_system_score_gemma":0.00010806896,"threshold_uncertainty_score":0.41337246},"labels":[],"label_agreement":null},{"id":"W4390660365","doi":"10.21203/rs.3.rs-3717633/v1","title":"Structure and engineering of Brevibacillus laterosporus Cas9","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Core Research for Evolutional Science and Technology; Japan Agency for Medical Research and Development","keywords":"Computer science; Biology","score_opus":0.015958029200626514,"score_gpt":0.3672311794056583,"score_spread":0.3512731502050318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390660365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9706699,0.027944835,0.00028667453,0.00006441628,0.00025414492,0.0003129629,0.00030167244,0.000018718238,0.00014663592],"genre_scores_gemma":[0.9971672,0.0014229232,0.0005913326,0.0000033657163,0.00029887608,0.00001927049,0.00014371789,0.000048120284,0.000305149],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871147,0.000033820117,0.00019654883,0.00045672635,0.0002819306,0.00031948],"domain_scores_gemma":[0.9992356,0.000018903573,0.000023889497,0.00046322218,0.00015091861,0.00010749963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028589493,0.0001973297,0.00022050456,0.00015942739,0.00002711805,0.00005069662,0.00019290794,0.00036794847,0.000020519561],"category_scores_gemma":[0.0001049419,0.00018733456,0.000088080364,0.000110794645,0.00006492352,7.476189e-7,0.0015249158,0.0007114642,0.0000028536258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033628767,0.000017651053,0.0012668999,0.008327453,0.00020539055,0.000043189124,0.0002981474,0.008728561,0.974698,0.00021408644,0.0012371241,0.0049298718],"study_design_scores_gemma":[0.00046255367,0.0004942521,0.015698424,0.0020072996,0.000065408305,0.00008768521,0.00015709965,0.0041994397,0.95256346,0.0012881352,0.022156173,0.00082005595],"about_ca_topic_score_codex":0.00005187277,"about_ca_topic_score_gemma":0.000018030152,"teacher_disagreement_score":0.026521912,"about_ca_system_score_codex":0.000020016898,"about_ca_system_score_gemma":0.00009908178,"threshold_uncertainty_score":0.7639282},"labels":[],"label_agreement":null},{"id":"W4390660864","doi":"10.1101/2024.01.05.574245","title":"Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Pharmacogenomics; Medicine; Cancer; Computational biology; Oncology; Pharmacology; Internal medicine; Biology","score_opus":0.014104237296220054,"score_gpt":0.3083584077102055,"score_spread":0.29425417041398544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390660864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96785676,0.023907935,0.0042983866,0.00015188492,0.002486887,0.00053749373,0.00065619,0.00009465571,0.000009789467],"genre_scores_gemma":[0.9815059,0.0101763,0.006883045,0.00024322137,0.0008049101,0.00017123681,0.0000028363986,0.00018177254,0.00003078231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971999,0.00012120318,0.00090272137,0.0010551729,0.0002533822,0.0004676446],"domain_scores_gemma":[0.99821204,0.000041868225,0.0002711385,0.0010454959,0.00023986207,0.00018956992],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004771205,0.0006020596,0.00078741426,0.00013850743,0.000047730016,0.000113282265,0.00058906135,0.0006236199,0.000024741174],"category_scores_gemma":[0.00011858629,0.0005737063,0.0005790641,0.0001546364,0.0001915033,0.0000050618564,0.0009757272,0.0006143912,0.000012463717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084072206,0.00010739302,0.011161076,0.00034947656,0.0013332724,0.000013800187,0.0000057828292,0.0027171683,0.98372936,0.000026544032,0.00045548426,0.000016589862],"study_design_scores_gemma":[0.0010080248,0.00008124317,0.05081705,0.00021546586,0.00037339272,1.20669865e-8,0.000002995317,0.00084073114,0.9425365,0.0000021761366,0.0032690405,0.0008533754],"about_ca_topic_score_codex":0.000024986462,"about_ca_topic_score_gemma":0.0000023119385,"teacher_disagreement_score":0.04119285,"about_ca_system_score_codex":0.000050446448,"about_ca_system_score_gemma":0.0006308708,"threshold_uncertainty_score":0.99967146},"labels":[],"label_agreement":null},{"id":"W4390685733","doi":"10.20944/preprints202401.0591.v1","title":"History, Development and Characteristics of CRISPR-Cas System","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"CRISPR; Cas9; Biology; Genome editing; DNA; Computational biology; Genetic enhancement; Gene; Somatic cell; Palindrome; Genetics","score_opus":0.04971436745339349,"score_gpt":0.32753194688932896,"score_spread":0.2778175794359355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390685733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98937404,0.004538878,0.0018041118,0.000026129308,0.0012235391,0.00026934443,0.00002777403,0.000050827817,0.0026853303],"genre_scores_gemma":[0.9973189,0.0002637213,0.0006564724,0.000016097982,0.00022388715,0.0000677395,0.00009693301,0.000051646468,0.0013045757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844176,0.00002913101,0.0004780797,0.00068831217,0.00015525427,0.00020747761],"domain_scores_gemma":[0.9989626,0.000007426069,0.00014892366,0.0006885209,0.00009067937,0.00010185164],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002895164,0.0002926072,0.00035167809,0.00008494868,0.000022293427,0.000007983029,0.00025544362,0.00033888474,0.00003418142],"category_scores_gemma":[0.000054374428,0.00031572048,0.000106774605,0.000025945012,0.00006074604,8.4695563e-7,0.0020819448,0.0003260339,0.00006846579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010177759,0.00011810948,0.12288979,0.011406078,0.00087476725,0.000052216103,0.002670177,0.00017705673,0.8550835,0.0005385776,0.0006786223,0.0054093325],"study_design_scores_gemma":[0.00015394257,0.000023303124,0.13427435,0.0004863406,0.00010893272,0.000029468825,0.00010261372,0.00013862527,0.7945253,0.000024557901,0.06968101,0.000451539],"about_ca_topic_score_codex":0.000025306897,"about_ca_topic_score_gemma":0.0000048252787,"teacher_disagreement_score":0.06900239,"about_ca_system_score_codex":0.00013258975,"about_ca_system_score_gemma":0.00023879141,"threshold_uncertainty_score":0.9999295},"labels":[],"label_agreement":null},{"id":"W4390731618","doi":"10.1016/j.scr.2024.103308","title":"Generation of a patient-specific iPSC cell line with cardiac arrhythmias and dilated cardiomyopathy (CBRCULi016-A), an isogenic control (CBRCULi016-A-1), and a paternal control (CBRCULi017-A)","year":2024,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Canadian Institutes of Health Research; Association Française contre les Myopathies","keywords":"Dilated cardiomyopathy; Biology; Cardiomyopathy; Internal medicine; Control line; Line (geometry); Cardiology; Heart failure; Medicine","score_opus":0.02261196776991389,"score_gpt":0.29780005961783024,"score_spread":0.27518809184791637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390731618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9527297,0.04015721,0.0056611556,0.000045111807,0.00017136158,0.0007271038,0.00020021206,0.000026758755,0.000281363],"genre_scores_gemma":[0.9961106,0.0027664895,0.00013600505,0.000017804996,0.0004890232,0.00007791586,0.00011255464,0.0000650632,0.00022453553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99755967,0.0003062203,0.00036983108,0.000744295,0.0004930978,0.00052690547],"domain_scores_gemma":[0.99886197,0.000053666274,0.00005532656,0.00046753394,0.0002783406,0.00028313664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006949957,0.00029228214,0.00037583243,0.00019563256,0.00014643224,0.00016234057,0.00014128919,0.00020728007,0.000012415604],"category_scores_gemma":[0.0000062087097,0.0002462888,0.00010925384,0.0002313366,0.0001942054,0.00001970079,0.00009848416,0.00032995688,0.0000060289685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036352786,0.000053784323,0.0011917063,0.0002469319,0.00015384721,0.000063666586,0.0005283175,0.0020270757,0.98530126,0.000017411605,0.00025546082,0.009796986],"study_design_scores_gemma":[0.003809757,0.00410977,0.0014380398,0.00012264424,0.00015084897,0.000099206416,0.0006664525,0.02355627,0.9465317,0.000012865621,0.01883285,0.0006695568],"about_ca_topic_score_codex":0.000060021914,"about_ca_topic_score_gemma":0.000015393462,"teacher_disagreement_score":0.043380886,"about_ca_system_score_codex":0.000031120646,"about_ca_system_score_gemma":0.00012848582,"threshold_uncertainty_score":0.9999989},"labels":[],"label_agreement":null},{"id":"W4390750892","doi":"10.1038/s41587-023-02085-z","title":"In vivo human T cell engineering with enveloped delivery vehicles","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":230,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Common Fund; Lawrence Livermore National Laboratory; National Institute of General Medical Sciences; National Human Genome Research Institute; U.S. Department of Health and Human Services; National Institutes of Health; Houston Advanced Research Center; U.S. Department of Energy; Gilead Sciences; Natural Sciences and Engineering Research Council of Canada; Jane Coffin Childs Memorial Fund for Medical Research; Emerson Collective; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute","keywords":"Genome editing; Cas9; CRISPR; Biology; Gene delivery; Genome engineering; Cell biology; Chimeric antigen receptor; Bystander effect; Antigen-presenting cell; T cell; Computational biology; Genetic enhancement; Gene; Immunology; Genetics; Immune system","score_opus":0.0020865383835286444,"score_gpt":0.2383922722913049,"score_spread":0.23630573390777626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390750892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.983709,0.011266644,0.003629885,0.00051459385,0.00024500245,0.000114779905,0.0000085037655,0.00013292786,0.00037867582],"genre_scores_gemma":[0.9966015,0.00026051776,0.0022094452,0.00008804027,0.00012744842,0.000013287101,0.000011488053,0.00003259948,0.000655672],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999234,0.0000054553734,0.00011048493,0.0003498754,0.00006336909,0.00023677303],"domain_scores_gemma":[0.9996989,0.0000071857617,0.000010986382,0.00023961073,0.000014415668,0.000028927983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006000396,0.00015322535,0.000110134584,0.00019554971,0.000020597952,0.000016446336,0.00016952703,0.00084742333,0.00001453895],"category_scores_gemma":[0.000011708334,0.00013763539,0.00003450019,0.00023066739,0.00003660719,0.0000031358347,0.000080363956,0.00052597746,0.000005888874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008538803,0.000012570776,0.000092741684,0.000052523934,0.000017641556,0.00006026665,0.000012987957,0.00040065442,0.9968742,0.0007931384,0.0011585683,0.0005161802],"study_design_scores_gemma":[0.0001795693,0.00011791502,0.00015611184,0.000029287059,0.000006775953,0.000037536727,0.000014271554,0.0004759224,0.862084,0.00001554469,0.13671724,0.00016586541],"about_ca_topic_score_codex":0.000008361879,"about_ca_topic_score_gemma":0.0000391035,"teacher_disagreement_score":0.13555868,"about_ca_system_score_codex":0.00001662874,"about_ca_system_score_gemma":0.000028137341,"threshold_uncertainty_score":0.65361047},"labels":[],"label_agreement":null},{"id":"W4390796822","doi":"10.1080/21645698.2023.2293510","title":"Risk-appropriate regulations for gene-editing technologies","year":2024,"lang":"en","type":"article","venue":"GM crops & food","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Scope (computer science); Food security; Emerging technologies; Agriculture; Genome editing; Business; Production (economics); Risk analysis (engineering); Biotechnology; Agricultural productivity; Biodiversity; Environmental resource management; CRISPR; Biology; Computer science; Gene; Ecology; Economics","score_opus":0.007938464863213006,"score_gpt":0.28008683418456537,"score_spread":0.2721483693213524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390796822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7190776,0.00884908,0.2700094,0.0003507387,0.0005785716,0.00029760352,0.00016505955,0.00030195987,0.00036997962],"genre_scores_gemma":[0.9857117,0.00015273641,0.013199058,0.000010669142,0.00039560214,0.00007906272,0.00008701589,0.000031415268,0.00033276592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929893,0.000007261885,0.00013604277,0.00028819148,0.000058402828,0.00021115456],"domain_scores_gemma":[0.9996427,0.000013668078,0.000024873149,0.00025492796,0.000039458428,0.000024321796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010723516,0.00011552551,0.00008087783,0.00005075594,0.00009777467,0.000052879368,0.00012021455,0.0001348526,0.000003955233],"category_scores_gemma":[0.000118275726,0.00010943795,0.00009525269,0.00009761756,0.00003620884,0.000002586093,0.00007408328,0.00008211644,0.0000070052465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019763102,0.000025603455,0.0005435934,0.00014640053,0.00024063849,0.000002791406,0.00016104327,0.0029328677,0.85223055,0.0012932471,0.0037750548,0.13862844],"study_design_scores_gemma":[0.00024652528,0.00031242103,0.0007779509,0.000026978714,0.000058796715,0.000019805642,0.00019614221,0.0033920067,0.87036484,0.001955394,0.122410886,0.00023822587],"about_ca_topic_score_codex":0.000004481427,"about_ca_topic_score_gemma":0.000022261818,"teacher_disagreement_score":0.26663408,"about_ca_system_score_codex":0.0000082017195,"about_ca_system_score_gemma":0.000025243025,"threshold_uncertainty_score":0.446275},"labels":[],"label_agreement":null},{"id":"W4390824361","doi":"10.1002/pld3.563","title":"Creating saponin‐free yellow pea seeds by <i>CRISPR/Cas9</i>‐enabled mutagenesis on β‐amyrin synthase","year":2024,"lang":"en","type":"article","venue":"Plant Direct","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada); Global Institute for Water Security; University of Saskatchewan; University of Calgary","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; RES’EAU-WaterNET; Alberta Innovates","keywords":"CRISPR; Mutagenesis; Cas9; Biology; Saponin; ATP synthase; Genetics; Computational biology; Mutation; Gene; Medicine","score_opus":0.005736655756264831,"score_gpt":0.25657986498748986,"score_spread":0.25084320923122505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390824361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9185469,0.016850216,0.0042533856,0.00029960138,0.0012548673,0.00041944583,0.0014530501,0.00037825483,0.056544244],"genre_scores_gemma":[0.99138445,0.0007250105,0.00041124696,0.00015718567,0.00044975293,0.00004486606,0.00050602,0.00007305604,0.006248411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860305,0.000045191806,0.00021819184,0.00054242456,0.00018666951,0.0004045043],"domain_scores_gemma":[0.9992577,0.00009162803,0.000028253118,0.00046701496,0.00002124805,0.00013417128],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021942916,0.00028381567,0.00021983351,0.000082240986,0.0000970744,0.00009373331,0.00024162028,0.00015077385,0.000067108514],"category_scores_gemma":[0.00014103545,0.00026484637,0.00013767235,0.00014238938,0.000029025927,0.000004206022,0.00010319522,0.0001372771,0.0000552147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007298469,0.00005744633,0.00019748003,0.00012991135,0.0001565407,0.00012104479,0.000101048994,0.0007733762,0.9072463,0.00002460809,0.0878848,0.0032344542],"study_design_scores_gemma":[0.00025551897,0.00016501939,0.00010200971,0.0001245968,0.00005941127,0.00005406344,0.000047893423,0.0018936251,0.8027065,0.0000068542895,0.19424072,0.0003438215],"about_ca_topic_score_codex":0.000078631514,"about_ca_topic_score_gemma":0.00003229328,"teacher_disagreement_score":0.10635592,"about_ca_system_score_codex":0.000024724375,"about_ca_system_score_gemma":0.000042903215,"threshold_uncertainty_score":0.9999804},"labels":[],"label_agreement":null},{"id":"W4390858353","doi":"10.1093/ismejo/wrae005","title":"<i>Escherichia coli</i> CRISPR arrays from early life fecal samples preferentially target prophages","year":2024,"lang":"en","type":"article","venue":"The ISME Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Det Sundhedsvidenskabelige Fakultet, Københavns Universitet; Natural Sciences and Engineering Research Council of Canada; Compute Canada; Canadian Institutes of Health Research; Faculty of Health and Medical Sciences, University of Western Australia; Alliance de recherche numérique du Canada; Canada First Research Excellence Fund; Novo Nordisk Fonden; Fonds de recherche du Québec – Nature et technologies; Danish Agency for Science and Higher Education; Copenhagen Graduate School for Nanoscience and Nanotechnology; Novo Nordisk","keywords":"Biology; Prophage; Escherichia coli; CRISPR; Feces; Microbiology; Lysogenic cycle; Genetics; Bacteriophage; Gene","score_opus":0.01205726318715176,"score_gpt":0.27264390833571894,"score_spread":0.26058664514856716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390858353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8385343,0.009082405,0.15022123,0.00081482437,0.00083588285,0.000110300156,0.000042437587,0.000031574506,0.0003270633],"genre_scores_gemma":[0.9929468,0.00059649564,0.003255686,0.00027996945,0.0023240994,0.000008477168,0.000026004813,0.0000403328,0.0005221348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990024,0.00007117884,0.00023563573,0.00022112753,0.00019714687,0.00027253694],"domain_scores_gemma":[0.99949765,0.000025425861,0.00004327835,0.00023421117,0.00004842977,0.00015099181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022094652,0.00017857306,0.00014202895,0.000028745624,0.00014792065,0.00025811887,0.0003120924,0.00010911361,0.00016069274],"category_scores_gemma":[0.00005139735,0.00012100599,0.00014765715,0.00007053251,0.000050108538,0.000007032693,0.000088360684,0.000365515,0.000031598123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004726827,0.00002551916,0.00020539883,0.00001868483,0.00024207808,0.0000097649845,0.00032670563,0.0013306873,0.98094904,0.000047529855,0.015466765,0.0013305745],"study_design_scores_gemma":[0.00057481084,0.0003976967,0.015878892,0.000096380914,0.00017770618,0.000066615336,0.00020677522,0.001033635,0.78676397,0.0014904804,0.19284812,0.00046494283],"about_ca_topic_score_codex":0.000029893587,"about_ca_topic_score_gemma":0.000009588566,"teacher_disagreement_score":0.19418508,"about_ca_system_score_codex":0.000010504116,"about_ca_system_score_gemma":0.00014653787,"threshold_uncertainty_score":0.4934481},"labels":[],"label_agreement":null},{"id":"W4390949709","doi":"10.54254/2754-1169/71/20241532","title":"Exploring Game Theory in the Realm of Genetically Modified Organisms: A Multidimensional Review","year":2024,"lang":"en","type":"review","venue":"Advances in Economics Management and Political Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Misinformation; Genetically modified organism; Context (archaeology); Agriculture; Order (exchange); Business; Realm; Game theory; Agricultural biotechnology; Public economics; Economics; Political science; Microeconomics","score_opus":0.05120316870952644,"score_gpt":0.36694394788799495,"score_spread":0.3157407791784685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390949709","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036468034,0.99376786,0.00019689955,0.00006770785,0.00012709449,0.0003622108,0.0000093646195,0.0000028026798,0.0051013553],"genre_scores_gemma":[0.0033044955,0.9956898,0.00063992117,0.00014815378,0.00005787753,0.00009522234,0.000011662641,0.000010704892,0.000042125517],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99871475,0.00007763924,0.00044048807,0.0003984456,0.00007186944,0.00029678896],"domain_scores_gemma":[0.9996066,0.00009504706,0.000054957836,0.00019374945,0.0000060487505,0.000043606182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075979676,0.00018896456,0.00042002954,0.0001035615,0.00002123827,0.000019176103,0.000310935,0.000052138454,0.0000028835561],"category_scores_gemma":[0.000036979316,0.00012527667,0.000092258764,0.00015926667,0.00025029096,0.000011329328,0.00021402842,0.000106584164,0.00000251969],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000027539338,0.00002511139,0.0000074829054,0.010253517,0.00002802424,0.0000053716394,0.000023337334,0.00015849431,0.0000010957832,0.43178207,0.000011389635,0.55770135],"study_design_scores_gemma":[0.00012075532,0.00011123498,0.000032799173,0.008103757,0.00023339827,0.00001764582,0.0001706084,0.00013379595,0.00001787315,0.012360186,0.97836876,0.00032920818],"about_ca_topic_score_codex":0.0000037621126,"about_ca_topic_score_gemma":0.00001450997,"teacher_disagreement_score":0.9783574,"about_ca_system_score_codex":0.00001622973,"about_ca_system_score_gemma":0.00003422121,"threshold_uncertainty_score":0.51086336},"labels":[],"label_agreement":null},{"id":"W4390966652","doi":"10.1016/b978-0-323-91808-4.00006-7","title":"CRISPR: the Janus god of modern science","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"CRISPR; Genome editing; Risk analysis (engineering); Biotechnology; Computer science; Engineering ethics; Nanotechnology; Computational biology; Engineering; Biology; Business; Genetics; Materials science","score_opus":0.008494309755079149,"score_gpt":0.276085787328529,"score_spread":0.26759147757344987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390966652","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00045856903,0.013379173,0.00020616983,0.000047786332,0.00043307504,0.00022793644,0.000033464457,0.000013743775,0.9852001],"genre_scores_gemma":[0.0950411,0.00026006426,0.0001373357,0.00007626381,0.00032448058,0.000012507429,0.000010901837,0.000056505563,0.9040808],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988571,0.000004116164,0.00024664652,0.0004172088,0.00025545168,0.00021947795],"domain_scores_gemma":[0.9990775,0.0000078939165,0.00006874545,0.0006860704,0.00009504812,0.000064755244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022047303,0.00024432864,0.0002023498,0.00007247933,0.00006650765,0.000031918058,0.00047333294,0.0001798665,0.000023259354],"category_scores_gemma":[0.000014665428,0.00018035911,0.00018558426,0.000015913494,0.00038835627,9.001412e-7,0.00031752785,0.0002179791,0.000028000522],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009744813,0.0000039358238,0.0000015851908,0.00013550083,0.0001050242,0.000006694557,0.00014629363,0.00006826031,0.11851334,0.0053821234,0.00019534244,0.87543213],"study_design_scores_gemma":[0.000071035975,0.00007264834,0.0000076404685,0.00012590979,0.00008662099,0.000023731574,0.000005664408,0.000079633806,0.07877788,0.006402547,0.9141091,0.00023756431],"about_ca_topic_score_codex":3.150078e-7,"about_ca_topic_score_gemma":0.00000789417,"teacher_disagreement_score":0.9139138,"about_ca_system_score_codex":0.000015204656,"about_ca_system_score_gemma":0.00015092934,"threshold_uncertainty_score":0.7354831},"labels":[],"label_agreement":null},{"id":"W4390987406","doi":"10.5376/ijmz.2024.14.0002","title":"Applications of Mouse Gene Editing Technology in the Treatment of Hereditary Blindness","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Zoology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genome editing; CRISPR; Blindness; Cas9; Genetic enhancement; Disease; Gene; Biology; Hereditary Diseases; Computational biology; Bioinformatics; Genetics; Medicine; Optometry; Pathology","score_opus":0.005100832555610999,"score_gpt":0.30298775938014094,"score_spread":0.29788692682452994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390987406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9083361,0.007845805,0.0824553,0.0008324545,0.00035694148,0.000084997555,0.000017206417,0.0000024923957,0.00006867573],"genre_scores_gemma":[0.99764585,0.00057136477,0.0013956913,0.0000298688,0.00029267932,0.000014140508,0.000018332099,0.000008750583,0.0000232917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993291,0.000028414024,0.00033171885,0.00009655608,0.00013500689,0.00007919779],"domain_scores_gemma":[0.99956584,0.000023370441,0.00010269514,0.00012628657,0.00016716914,0.000014625237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000131328,0.00007151915,0.00012427518,0.00024944957,0.000006126429,0.0000051931042,0.00030452048,0.0000907586,0.00000545374],"category_scores_gemma":[0.00003001687,0.000054682503,0.00010482871,0.00011751611,0.00006633551,0.0000026184434,0.000026671527,0.000072571085,6.430773e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037344435,0.0002125297,0.0008267044,0.000012219685,0.0002549536,0.000149223,0.00014079068,0.0019690124,0.9746015,0.0007383531,0.00006072983,0.020996643],"study_design_scores_gemma":[0.00042534934,0.0005440495,0.00024496444,0.000021271726,0.000031196614,0.0006277887,0.0002335873,0.00012869721,0.99008846,0.0006033887,0.00700055,0.000050704166],"about_ca_topic_score_codex":0.000008277492,"about_ca_topic_score_gemma":0.000007256317,"teacher_disagreement_score":0.08930975,"about_ca_system_score_codex":0.000017374947,"about_ca_system_score_gemma":0.00005602889,"threshold_uncertainty_score":0.22298877},"labels":[],"label_agreement":null},{"id":"W4391050640","doi":"10.1101/2024.01.18.24301006","title":"Identification of a novel mosaic <i>MTOR</i> variant in purified neuronal DNA from depth electrodes in a patient with focal cortical dysplasia","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Children's Hospital Research Institute; Azrieli Foundation; Health Canada; Alberta Children's Hospital Foundation; Government of Canada; Children's Hospital Foundation; Canadian Bee Research Fund; Fondation Brain Canada; University of Calgary","keywords":"Cortical dysplasia; Electroencephalography; Insula; Somatic cell; Stereoelectroencephalography; Epilepsy; Biology; Pathology; Neuroscience; Ictal; Anatomy; Molecular biology; Medicine; Genetics; Gene","score_opus":0.00790058089197346,"score_gpt":0.2563010532010099,"score_spread":0.24840047230903642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391050640","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98433787,0.00075748283,0.014139242,0.00006208268,0.00023451811,0.00030649843,0.00009980819,0.000011568111,0.000050946797],"genre_scores_gemma":[0.9987808,0.00007389982,0.00063655264,0.000025170692,0.000080338075,0.00010025909,0.00024907035,0.000038487877,0.000015439678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836636,0.000050680537,0.00050852005,0.0006286432,0.00020240259,0.00024337339],"domain_scores_gemma":[0.99937415,0.000022214677,0.00009532045,0.00041083927,0.000038741717,0.00005872131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016254913,0.00023686039,0.00027215944,0.00011183223,0.000010092014,0.00002541664,0.00020114906,0.00024804985,0.00000376964],"category_scores_gemma":[0.000067089,0.00022169302,0.000072064475,0.00013641467,0.000047631256,0.0000014649298,0.00027608094,0.0004684621,0.0000018360179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016463255,0.00020747262,0.0052841813,0.00011675705,0.0000570683,0.000065462336,0.00015909199,0.006532525,0.9869104,0.000052837655,0.000025043273,0.0004245534],"study_design_scores_gemma":[0.0007672987,0.00029167894,0.08628029,0.00022293483,0.00007087819,0.000042908207,0.00004030736,0.010773922,0.9008007,0.00019490258,0.0001458443,0.00036832664],"about_ca_topic_score_codex":0.0001226663,"about_ca_topic_score_gemma":0.0007933063,"teacher_disagreement_score":0.08610967,"about_ca_system_score_codex":0.000029181461,"about_ca_system_score_gemma":0.0001558856,"threshold_uncertainty_score":0.90403783},"labels":[],"label_agreement":null},{"id":"W4391059514","doi":"10.1016/b978-0-443-18444-4.00024-7","title":"Regulatory outlook of CRISPR-edited plants in Canada","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"CRISPR; Biology; Genetics; Gene","score_opus":0.005914315914256033,"score_gpt":0.23563229190945303,"score_spread":0.229717975995197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391059514","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006887408,0.010661474,0.000008118339,0.000017074633,0.00082239124,0.00025486475,0.00018682977,0.000009993798,0.9811518],"genre_scores_gemma":[0.114932306,0.0002569975,0.000048129976,0.000080960526,0.00031982243,0.000011616036,0.00011751192,0.00008252076,0.88415015],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988279,0.0000063239518,0.00038104333,0.00037026402,0.00019986836,0.00021462292],"domain_scores_gemma":[0.9993575,0.000008715743,0.00007906461,0.00044167007,0.000034943554,0.00007808754],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000808054,0.000283545,0.0003339602,0.0000949075,0.000011514531,0.000006088069,0.0001873163,0.00025609444,0.0000367861],"category_scores_gemma":[0.0000068437203,0.00029368032,0.00010983628,0.000007834468,0.000039851988,5.3172107e-7,0.000121740595,0.00023693759,0.0000078310395],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001028761,0.000015633881,0.00023666222,0.0013776516,0.0006770151,0.00033710885,0.00020096444,0.00038330763,0.055953518,0.0014313177,0.008902181,0.9303818],"study_design_scores_gemma":[0.00019005025,0.000041777264,0.00016044479,0.00040524668,0.000042426855,0.00001635254,0.000016051248,0.000018134095,0.03176735,0.00038235955,0.96660286,0.00035695365],"about_ca_topic_score_codex":0.0024372442,"about_ca_topic_score_gemma":0.29320002,"teacher_disagreement_score":0.95770067,"about_ca_system_score_codex":0.000087656284,"about_ca_system_score_gemma":0.0006112651,"threshold_uncertainty_score":0.99995154},"labels":[],"label_agreement":null},{"id":"W4391116233","doi":"10.1016/j.foodchem.2024.138557","title":"Highly sensitive detection of aflatoxin B1 byCRISPR/Cas12a-assisted single nanoparticle counting","year":2024,"lang":"en","type":"article","venue":"Food Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Detection limit; Amplicon; Aptamer; Magnetic nanoparticles; Chromatography; Nanoparticle; Chemistry; Nanotechnology; Materials science; Biology; Molecular biology; Polymerase chain reaction; Gene","score_opus":0.007209567648096225,"score_gpt":0.24607995485786383,"score_spread":0.2388703872097676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391116233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933952,0.0015462695,0.0036712356,0.000037441,0.00018320556,0.00006065225,0.000029046025,0.000056598758,0.0010203506],"genre_scores_gemma":[0.9991023,0.0000184377,0.00022553284,0.000015003135,0.0002404187,0.000008316175,0.00003763199,0.000031215754,0.00032115864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991377,0.000010427105,0.00021074813,0.00030515026,0.000121738536,0.0002142416],"domain_scores_gemma":[0.9995868,0.000015268322,0.000040912288,0.00022871088,0.00006719149,0.00006110158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088949535,0.00014679879,0.0001262673,0.000019618874,0.00003797877,0.000030642506,0.000076877805,0.00014223233,0.0000068847166],"category_scores_gemma":[0.00005105894,0.00015834082,0.00009899336,0.00013832159,0.00004500193,0.000004035234,0.000060810547,0.00009696833,0.000005448477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021713458,0.000033603657,0.00002296399,0.00019158893,0.00008000261,0.000006195368,0.000050785897,0.00014611107,0.99688995,0.0000033711344,0.00011431373,0.0024394218],"study_design_scores_gemma":[0.00018166397,0.00014758187,0.00012142867,0.00006015752,0.00003697313,0.0000613015,0.000120172794,0.00063794194,0.9937426,0.000010312137,0.004704942,0.00017495858],"about_ca_topic_score_codex":0.000005939305,"about_ca_topic_score_gemma":0.000008528601,"teacher_disagreement_score":0.0057070847,"about_ca_system_score_codex":0.000024300798,"about_ca_system_score_gemma":0.000034023393,"threshold_uncertainty_score":0.6456951},"labels":[],"label_agreement":null},{"id":"W4391123054","doi":"10.1016/j.celrep.2024.113684","title":"Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer","year":2024,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research; Horizon 2020 Framework Programme; Terry Fox Research Institute; Canada Research Chairs; Chugai Pharmaceutical; European Commission; Princess Margaret Cancer Foundation; Pfizer","keywords":"Mimicry; Dependency (UML); Exonuclease; Biology; Cancer; Retrotransposon; Molecular mimicry; Virology; Computational biology; Genetics; Cell biology; Genome; Transposable element; DNA; Computer science; Gene; Ecology; Artificial intelligence","score_opus":0.005692620234086908,"score_gpt":0.2815429532031782,"score_spread":0.2758503329690913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391123054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9732279,0.022710085,0.0011081395,0.00022761428,0.00050084165,0.0001577558,0.000010615737,0.000013634073,0.0020434214],"genre_scores_gemma":[0.9946141,0.0008417004,0.00007301876,0.00023351258,0.00014944286,0.000040625597,0.000028432403,0.000023179682,0.00399598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915564,0.000012173151,0.00020801225,0.00032286323,0.00010600013,0.00019531112],"domain_scores_gemma":[0.9995904,0.0000037904576,0.000028974278,0.0003125635,0.000014750889,0.00004954194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014336879,0.00011149068,0.00007164755,0.00002316117,0.00002758601,0.000030259787,0.0000763275,0.00007161356,0.00010434615],"category_scores_gemma":[0.00000824451,0.000088444765,0.00006588415,0.00006128372,0.000018073659,0.000001536972,0.00006958765,0.000093878596,0.000004629056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000070208544,0.000027700466,0.0022859108,0.000049328894,0.000020116493,0.00021039216,0.00011668939,0.00017684682,0.93441635,0.0000023664425,0.0581205,0.0045667957],"study_design_scores_gemma":[0.000072641924,0.00004112925,0.0005127383,0.000022310825,0.00001531847,0.00006628991,0.000037299716,0.00015685313,0.7666319,0.000024702029,0.23229763,0.00012119691],"about_ca_topic_score_codex":0.00012141542,"about_ca_topic_score_gemma":0.00008084017,"teacher_disagreement_score":0.17417713,"about_ca_system_score_codex":0.00002205133,"about_ca_system_score_gemma":0.00006759285,"threshold_uncertainty_score":0.3606673},"labels":[],"label_agreement":null},{"id":"W4391124521","doi":"10.1016/j.crmeth.2023.100693","title":"A mobile CRISPRi collection enables genetic interaction studies for the essential genes of Escherichia coli","year":2024,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario; Canada Foundation for Innovation; Ontario Research Foundation","keywords":"Gene knockdown; CRISPR; CRISPR interference; Gene; Biology; Plasmid; Genetic screen; Phenotype; Genetics; Cas9; Computational biology; Escherichia coli; RNA interference; RNA","score_opus":0.02095942574722171,"score_gpt":0.40779823368204776,"score_spread":0.38683880793482606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391124521","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2796052,0.08747855,0.630061,0.00001548802,0.0022010163,0.00043147366,0.0000022847332,0.000020436724,0.00018459353],"genre_scores_gemma":[0.87897354,0.0072030732,0.11046116,0.000017190501,0.0004944833,0.00038387108,0.000013030657,0.000039630882,0.0024139897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910986,0.00006752757,0.0003202726,0.000290863,0.0000728595,0.00013862847],"domain_scores_gemma":[0.9993625,0.0001244037,0.00009210826,0.00027154243,0.00012255443,0.000026875914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000469073,0.00012523528,0.00015675124,0.00004509017,0.00008115351,0.000028091794,0.000061010556,0.000080102465,0.000010223923],"category_scores_gemma":[0.00013941062,0.00009496704,0.00014686234,0.0001301773,0.000052258543,0.0000029235232,0.000061370105,0.000059192247,3.1452205e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002339665,0.000020693577,0.000032060812,0.0002683017,0.0001597104,0.0000054555326,0.00025484836,0.008282844,0.9679786,0.0000031724674,0.0020451376,0.020925775],"study_design_scores_gemma":[0.000059812704,0.00016535165,0.00006979285,0.000019951423,0.00012705963,0.000040315117,0.0005565377,0.0043230406,0.84819126,0.00008449616,0.14626938,0.00009301466],"about_ca_topic_score_codex":0.000016578175,"about_ca_topic_score_gemma":0.0000067776245,"teacher_disagreement_score":0.5993684,"about_ca_system_score_codex":0.000015340516,"about_ca_system_score_gemma":0.000068621244,"threshold_uncertainty_score":0.38726434},"labels":[],"label_agreement":null},{"id":"W4391132414","doi":"10.33137/juls.v16i1.42386","title":"Virus-Like Particles as a CRISPR-Cas9 Delivery Tool","year":2024,"lang":"en","type":"article","venue":"Journal of Undergraduate Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Virology; Virus; Biology; Genetics; Gene","score_opus":0.015463092979918618,"score_gpt":0.317827465132835,"score_spread":0.3023643721529164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391132414","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96860975,0.014415559,0.011124547,0.0042033396,0.0010781173,0.000051440078,0.0000033017382,0.000014371653,0.0004995534],"genre_scores_gemma":[0.9947404,0.002470361,0.0016307337,0.00042164308,0.00045987178,0.0000012805733,8.063202e-7,0.000010601477,0.0002642557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989114,0.000035423964,0.0003116967,0.00019666694,0.00031559655,0.00022922763],"domain_scores_gemma":[0.99957556,0.00003601564,0.00007349442,0.00011076241,0.00007601968,0.00012814159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005000744,0.00011674167,0.000128589,0.00010811044,0.00009817614,0.00012996541,0.00026153098,0.00005265173,0.000015445088],"category_scores_gemma":[0.000138032,0.000088602224,0.00014551876,0.000235897,0.00014295307,0.000021694075,0.00006264673,0.00011200051,0.000025126672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005332186,0.00005669739,0.00069436367,0.000050353377,0.00015120207,0.00008657819,0.00013791729,0.0054144203,0.9520924,0.0013733467,0.0313926,0.008496772],"study_design_scores_gemma":[0.00066218135,0.0022518723,0.0012712731,0.0002519734,0.00015221845,0.0010037046,0.0007944428,0.0066254064,0.7416015,0.012017843,0.23273812,0.00062945485],"about_ca_topic_score_codex":0.000012922915,"about_ca_topic_score_gemma":0.000013303561,"teacher_disagreement_score":0.21049093,"about_ca_system_score_codex":0.000010466115,"about_ca_system_score_gemma":0.0003137625,"threshold_uncertainty_score":0.36130938},"labels":[],"label_agreement":null},{"id":"W4391161230","doi":"10.1101/2024.01.22.575834","title":"Treatment of a genetic liver disease in mice through transient prime editor expression","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"Universität Zürich; Eidgenössische Technische Hochschule Zürich","keywords":"Genome editing; In vivo; Prime (order theory); Gene; Messenger RNA; Ex vivo; Vector (molecular biology); Locus (genetics); Molecular biology; Biology; Computational biology; Genome; Genetics; Recombinant DNA; Mathematics","score_opus":0.007546426309993541,"score_gpt":0.24450750936612495,"score_spread":0.2369610830561314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391161230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9632985,0.029490551,0.0038422972,0.00005033456,0.0022692583,0.000710855,0.00027983068,0.000053975993,0.000004397375],"genre_scores_gemma":[0.9899809,0.0031584536,0.0045212433,0.000016336679,0.0019670592,0.0002384844,0.0000018820446,0.00010544577,0.000010203736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979956,0.000058509497,0.00045552084,0.00090381806,0.00022064112,0.00036589967],"domain_scores_gemma":[0.99873704,0.000012206138,0.000117394295,0.0008395993,0.00011017982,0.00018360093],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000074675096,0.0004706976,0.0003929231,0.00012030615,0.000028056467,0.000038342972,0.00026365404,0.00038672562,0.0000115112525],"category_scores_gemma":[0.000032067663,0.00046394643,0.00022885685,0.0001580349,0.000066329805,0.000003496852,0.000272547,0.00020368728,0.000011517399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008807704,0.00027812264,0.0013677367,0.00060936046,0.00008791277,0.00007527082,0.000040240124,0.0016176973,0.9955389,0.0000070610363,0.0002834764,0.0000061517544],"study_design_scores_gemma":[0.0005357142,0.00018314886,0.031430576,0.0004430442,0.00014390348,2.0170535e-8,0.0000020256307,0.00067114737,0.9550514,0.000001401629,0.011037003,0.00050057337],"about_ca_topic_score_codex":0.00007608341,"about_ca_topic_score_gemma":0.000005541626,"teacher_disagreement_score":0.04048745,"about_ca_system_score_codex":0.00010750683,"about_ca_system_score_gemma":0.00038219203,"threshold_uncertainty_score":0.99978125},"labels":[],"label_agreement":null},{"id":"W4391174448","doi":"10.1038/s41556-023-01342-2","title":"C-to-G editing generates double-strand breaks causing deletion, transversion and translocation","year":2024,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China; Science and Technology Commission of Shanghai Municipality; Natural Science Foundation of Shanghai","keywords":"Biology; Chromosomal translocation; DNA damage; DNA; DNA repair; Transversion; Double strand; Genetics; AP site; Non-homologous end joining; Cell biology; Computational biology; Gene; Mutation","score_opus":0.004335888238074236,"score_gpt":0.2923280547196429,"score_spread":0.28799216648156867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391174448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9094679,0.027268888,0.061180405,0.0006186083,0.0008146024,0.00016806369,0.000022040076,0.000039363993,0.00042014872],"genre_scores_gemma":[0.9970768,0.0006977693,0.0010474755,0.00018419772,0.0006475995,0.000007930181,0.00021984501,0.000018298615,0.00010006582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992751,0.000018366285,0.00012454807,0.00035382577,0.000040863975,0.00018730195],"domain_scores_gemma":[0.99976623,0.000011218915,0.000011192494,0.00010237141,0.000039799652,0.00006919036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117724936,0.00013256959,0.00009686697,0.00006893083,0.0000631663,0.000028956738,0.000051099792,0.00041366325,0.000010324883],"category_scores_gemma":[0.0000064571464,0.00012215642,0.000041850428,0.00010156975,0.000030013074,0.0000030140354,0.000016700904,0.00019977518,0.0000031162438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033303,0.0000061761475,0.00008149337,0.00005542492,0.000016318067,0.0000028269649,0.0001327667,0.0006032872,0.989915,0.000059392874,0.0005247615,0.0085692555],"study_design_scores_gemma":[0.0003737915,0.00010819379,0.00013103249,0.000026279818,0.000021214297,0.00002823575,0.000037858932,0.00085253705,0.92742336,0.000024683372,0.07081626,0.00015653961],"about_ca_topic_score_codex":0.000012297477,"about_ca_topic_score_gemma":0.00003827249,"teacher_disagreement_score":0.08760894,"about_ca_system_score_codex":0.000007610652,"about_ca_system_score_gemma":0.000023354221,"threshold_uncertainty_score":0.4981394},"labels":[],"label_agreement":null},{"id":"W4391211052","doi":"10.7554/elife.84756.sa0","title":"Editor's evaluation: A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Resistance (ecology); Computational biology; Computer science; Biology; Genetics; Evolutionary biology; Ecology","score_opus":0.05523674635478362,"score_gpt":0.4305805819077313,"score_spread":0.3753438355529477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391211052","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034862047,0.0597268,0.9009691,0.021558892,0.008498611,0.00543492,0.0025401418,0.000047273457,0.0008756685],"genre_scores_gemma":[0.0792671,0.010799634,0.5191369,0.005769793,0.07330053,0.018604321,0.18002152,0.0006681413,0.11243204],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99833125,0.00022066414,0.00047231454,0.00030148917,0.0005211883,0.00015311096],"domain_scores_gemma":[0.9981474,0.0006595156,0.00019389181,0.0003099226,0.000671136,0.00001812333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017600603,0.00017644766,0.00021032947,0.000060579685,0.00012590819,0.000018795514,0.00027824604,0.00016224469,0.000014599729],"category_scores_gemma":[0.00097347767,0.00012353412,0.00013653027,0.0003281932,0.0000479027,0.0000041405506,0.00004595835,0.00014479995,8.262844e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000180685,0.0000258446,0.000030421592,0.0007472237,0.00008382194,1.4167756e-7,0.00024173356,0.12427386,0.00012682732,0.000064338186,0.8714074,0.0029803333],"study_design_scores_gemma":[0.0010538416,0.00016472892,0.0077920277,0.0012808449,0.00063639507,0.000008678349,0.001057762,0.1690175,0.0003251719,0.002021642,0.8161618,0.00047961713],"about_ca_topic_score_codex":0.000054051397,"about_ca_topic_score_gemma":0.000548116,"teacher_disagreement_score":0.38183215,"about_ca_system_score_codex":0.000032848395,"about_ca_system_score_gemma":0.00038554275,"threshold_uncertainty_score":0.50375754},"labels":[],"label_agreement":null},{"id":"W4391316951","doi":"10.1038/s41587-023-02091-1","title":"An optimized toolkit for prime editing","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Prime (order theory); Translation (biology); Computer science; Genome editing; Computational biology; Biology; Genetics; Mathematics; CRISPR; Combinatorics","score_opus":0.0034760682017544483,"score_gpt":0.3100163378307407,"score_spread":0.30654026962898623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391316951","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2017561,0.032215204,0.7552932,0.0046649734,0.003681641,0.00075810665,0.00011206422,0.0008251699,0.0006935605],"genre_scores_gemma":[0.96570534,0.00015531229,0.032369256,0.00016948847,0.0010310514,0.000044339125,0.00015663153,0.00003885787,0.00032971916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991812,0.0000077429395,0.00011647083,0.0004027131,0.00005145074,0.00024038219],"domain_scores_gemma":[0.99956894,0.000012426976,0.000015734267,0.0003317366,0.000032740387,0.000038450373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012626489,0.00013101286,0.000111267094,0.00009263498,0.00004206138,0.000030191162,0.00021645581,0.0011930348,0.000009810953],"category_scores_gemma":[0.00010791163,0.0001234616,0.00007859757,0.000108549466,0.00004425074,0.0000028232887,0.000055005043,0.0003345001,0.000004830389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002409776,0.000013473704,0.000007089057,0.000031789004,0.000040706982,0.000003995207,0.0000080233385,0.0001594048,0.96999127,0.0028046742,0.003036759,0.023878733],"study_design_scores_gemma":[0.00019637903,0.00020045921,0.000014954926,0.000011239327,0.000014118295,0.000027824279,0.000020046169,0.0027923337,0.7139201,0.000157191,0.282522,0.00012331965],"about_ca_topic_score_codex":0.0000011027125,"about_ca_topic_score_gemma":0.00000346284,"teacher_disagreement_score":0.7639492,"about_ca_system_score_codex":0.000009541539,"about_ca_system_score_gemma":0.000032892738,"threshold_uncertainty_score":0.9201777},"labels":[],"label_agreement":null},{"id":"W4391317512","doi":"10.1007/978-3-031-30023-3_9","title":"Genomics, Other “OMIC” Technologies, Precision Medicine, and Additional Biotechnology-Related Techniques","year":2024,"lang":"en","type":"book-chapter","venue":"Pharmaceutical biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biotechnology; Precision medicine; Computational biology; Genomics; Biology; Data science; Engineering; Computer science; Genetics; Genome; Gene","score_opus":0.019641726709367053,"score_gpt":0.3262943696754064,"score_spread":0.3066526429660394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391317512","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016463377,0.35863456,0.015007449,0.13333713,0.003874343,0.0059175645,0.01010128,0.013426145,0.4580552],"genre_scores_gemma":[0.049222823,0.3269145,0.028672438,0.0046969242,0.0031568725,0.00090568454,0.007480703,0.002225908,0.5767242],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972272,0.000012594483,0.00067166996,0.0013352715,0.00020132039,0.0005519815],"domain_scores_gemma":[0.99876,0.000067589,0.0001535946,0.00084194535,0.00006401547,0.000112886635],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022629667,0.00072970183,0.00061947457,0.0007562335,0.0000948326,0.000024093937,0.0006391404,0.0047874902,0.0012198032],"category_scores_gemma":[0.00018760304,0.00067405077,0.00017065505,0.000130144,0.0019213189,0.0000042699876,0.0010689227,0.0016656207,0.0002016601],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078606,0.000034572484,0.000002242477,0.0001723906,0.00056979695,0.00006696199,0.000010623826,0.0000027589192,0.49564856,0.22472407,0.07926152,0.1994279],"study_design_scores_gemma":[0.00023445321,0.00026822687,4.897332e-7,0.00019215596,0.00012946613,0.00027768212,0.000014348355,0.00009935684,0.28611094,0.029947372,0.6822496,0.00047594297],"about_ca_topic_score_codex":0.0000036879173,"about_ca_topic_score_gemma":0.0000073832825,"teacher_disagreement_score":0.60298806,"about_ca_system_score_codex":0.00007888817,"about_ca_system_score_gemma":0.000067067966,"threshold_uncertainty_score":0.9996932},"labels":[],"label_agreement":null},{"id":"W4391328002","doi":"10.20944/preprints202401.1948.v1","title":"CRISPR/CAS Genome Editing Technology: Implications And Challenges","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Genome; Computer science; Biology; Genetics; Gene","score_opus":0.07024387818540614,"score_gpt":0.3698412558213853,"score_spread":0.29959737763597916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391328002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9332077,0.05280018,0.0012722244,0.006426558,0.0005857998,0.0004651545,0.00006804583,0.00021235233,0.0049619866],"genre_scores_gemma":[0.98130506,0.016635465,0.00050933077,0.000044374727,0.00072281045,0.0002494388,0.00008739008,0.00006711162,0.00037904162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981707,0.000021747004,0.00029713177,0.0010943171,0.00009532765,0.00032077893],"domain_scores_gemma":[0.99858034,0.0000095304495,0.00008442476,0.0011314217,0.00008997699,0.00010432947],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025186109,0.00032225897,0.0002557205,0.00017339691,0.000075181786,0.000023668548,0.00040127774,0.00060390204,0.000030468376],"category_scores_gemma":[0.00013255158,0.00035720278,0.00011446446,0.0000836275,0.00010416765,0.0000015503352,0.0039059895,0.00062601746,0.00013079413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010035557,0.0000619147,0.03257851,0.0011710457,0.00040340176,0.000011286069,0.00046352707,0.0006858689,0.9553559,0.0015692578,0.000111843336,0.007577444],"study_design_scores_gemma":[0.0003015806,0.000068669775,0.23723851,0.00027155818,0.0002270411,0.0001461762,0.00054504996,0.00011524917,0.61947495,0.013621829,0.12689519,0.0010941747],"about_ca_topic_score_codex":0.000009878814,"about_ca_topic_score_gemma":0.000017961975,"teacher_disagreement_score":0.3358809,"about_ca_system_score_codex":0.00002806196,"about_ca_system_score_gemma":0.00006814517,"threshold_uncertainty_score":0.999888},"labels":[],"label_agreement":null},{"id":"W4391328137","doi":"10.20944/preprints202401.1947.v1","title":"Gene Editing, Indiscriminate Degradation And Recyclic Catalytic Events In Crispr Cas Technology","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"CRISPR; Genome editing; Degradation (telecommunications); Gene; Computational biology; Genetics; Computer science; Biology; Telecommunications","score_opus":0.0376166491740584,"score_gpt":0.3564176421740309,"score_spread":0.3188009929999725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391328137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99412453,0.0030601502,0.00041793237,0.00042989803,0.0007629397,0.00043766643,0.000027915796,0.000064316184,0.00067465595],"genre_scores_gemma":[0.9969916,0.0010013239,0.00030077554,0.00002928181,0.00025927814,0.00016525337,0.00027871117,0.000060641643,0.0009131657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980063,0.000039931958,0.0004113296,0.0010506875,0.00014180712,0.0003499774],"domain_scores_gemma":[0.998945,0.0000081667995,0.00011262373,0.0007973082,0.00005212467,0.00008477147],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003438792,0.00034112151,0.00029427707,0.00034244714,0.000039190443,0.000012437401,0.00033805927,0.0006652506,0.000019068088],"category_scores_gemma":[0.00021358622,0.0003817942,0.00008746472,0.00015540844,0.00006842876,0.0000028642155,0.0026524917,0.00074651506,0.00009916334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003448569,0.000105464416,0.45956865,0.0008260716,0.00020097532,0.000052054485,0.00056355394,0.0007980843,0.5321601,0.00006657863,0.00013256464,0.0054914383],"study_design_scores_gemma":[0.0002938164,0.000032759184,0.117301136,0.00023468395,0.000080871396,0.00006471764,0.00010515808,0.0002250269,0.877758,0.0021536874,0.0013316963,0.000418389],"about_ca_topic_score_codex":0.00021275014,"about_ca_topic_score_gemma":0.00019400047,"teacher_disagreement_score":0.34559795,"about_ca_system_score_codex":0.000068589456,"about_ca_system_score_gemma":0.00008799383,"threshold_uncertainty_score":0.9998634},"labels":[],"label_agreement":null},{"id":"W4391347872","doi":"10.1038/s41598-024-51735-y","title":"A scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research; Clinical and Translational Science Institute, University of Minnesota; Ontario Research Foundation; University of Minnesota; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Scalability; Computational biology; Cas9; Genetic screen; Genome; Genome editing; DNA damage; Biology; Computer science; Gene; DNA; Genetics; Phenotype","score_opus":0.012275805898486411,"score_gpt":0.2895897856619811,"score_spread":0.2773139797634947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391347872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9616558,0.0016544714,0.032236554,0.000037608905,0.0030607355,0.0003793174,0.00001856737,0.000043202876,0.00091375987],"genre_scores_gemma":[0.9936029,0.0000065233908,0.0047203084,0.000010819398,0.00018277332,0.000034829747,0.00015352576,0.00003597738,0.0012523499],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99806327,0.000007730711,0.00048901787,0.0007875093,0.00027649078,0.00037598383],"domain_scores_gemma":[0.9988732,0.000022868622,0.000088989465,0.00074304413,0.0001516954,0.00012025794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006609575,0.00018119348,0.00019752089,0.00013147101,0.00011797231,0.00015141332,0.00015831194,0.00012192014,0.000021058322],"category_scores_gemma":[0.000121056066,0.00017218245,0.00019202664,0.0003006874,0.00015949667,0.000004650185,0.00013124541,0.00007838938,0.0000045369306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010061993,0.000040470863,0.00011643785,0.00019693044,0.000039906034,0.000029255125,0.000093218936,0.0033810732,0.9854052,0.000030743817,0.009318256,0.0013384145],"study_design_scores_gemma":[0.00012458644,0.000061244165,0.00015576917,0.00009635629,0.00004099646,0.00015084252,0.00006479531,0.00940536,0.94961286,0.00026513924,0.03981782,0.0002042357],"about_ca_topic_score_codex":0.000011875417,"about_ca_topic_score_gemma":0.000006671038,"teacher_disagreement_score":0.035792377,"about_ca_system_score_codex":0.000023856204,"about_ca_system_score_gemma":0.00015116936,"threshold_uncertainty_score":0.7021397},"labels":[],"label_agreement":null},{"id":"W4391406569","doi":"10.1016/j.crmeth.2024.100698","title":"One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics","year":2024,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary; Alberta Children's Hospital Research Institute","keywords":"Sanger sequencing; Computational biology; Computer science; genomic DNA; DNA sequencing; Biology; Genetics; Gene","score_opus":0.017330566006710596,"score_gpt":0.3754103371465477,"score_spread":0.35807977113983713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391406569","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41416946,0.116581105,0.4679818,0.000018492174,0.0006971303,0.00032630304,0.000011931584,0.000014945607,0.00019884293],"genre_scores_gemma":[0.7860261,0.0069267997,0.2063089,0.000020637082,0.00048759996,0.000018921597,0.000025858302,0.000033776247,0.00015142027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873143,0.00008498592,0.00045616247,0.00045867052,0.00009151641,0.00017723432],"domain_scores_gemma":[0.9990688,0.00042870638,0.000097924734,0.00024778888,0.000066189066,0.00009061234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00124639,0.00013987516,0.00022785335,0.00005073488,0.000041068855,0.00003083861,0.000050670904,0.0002196791,0.0000049601545],"category_scores_gemma":[0.00094209117,0.00012874416,0.00010046072,0.000055288165,0.0000744722,0.0000013649363,0.00010802468,0.0001213435,7.102707e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023364943,0.000052160503,0.00050234224,0.0005889309,0.000080710684,0.000034473254,0.00013050955,0.0029303662,0.86643416,0.0000061333835,0.00044758493,0.12876928],"study_design_scores_gemma":[0.0003323666,0.0006049429,0.0113771865,0.00015424083,0.0002954694,0.00013133556,0.000116684234,0.006377356,0.8994597,0.0003079025,0.080469154,0.00037363148],"about_ca_topic_score_codex":0.0000036348115,"about_ca_topic_score_gemma":0.0000012786883,"teacher_disagreement_score":0.37185663,"about_ca_system_score_codex":0.0000047152234,"about_ca_system_score_gemma":0.000042235566,"threshold_uncertainty_score":0.52500343},"labels":[],"label_agreement":null},{"id":"W4391424462","doi":"10.1016/j.pestbp.2024.105810","title":"CRISPR/Cas9-mediated ebony knockout causes melanin pigmentation and prevents moth Eclosion in Ectropis grisescens","year":2024,"lang":"en","type":"article","venue":"Pesticide Biochemistry and Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"Biology; Mutant; CRISPR; PEST analysis; Genetics; Melanin; Gene; Botany","score_opus":0.005770000535236108,"score_gpt":0.2873862494533473,"score_spread":0.28161624891811116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391424462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937776,0.0052241883,0.0005646876,0.00008745434,0.00011437292,0.00011290189,0.000035119425,0.000024746989,0.00005894038],"genre_scores_gemma":[0.99775565,0.0013307427,0.00020195832,0.00007830331,0.00017396592,0.000024341321,0.00028856963,0.000019534884,0.00012690826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990485,0.000032686898,0.00018583542,0.0004424993,0.00005686481,0.0002336606],"domain_scores_gemma":[0.9996838,0.000045401415,0.000027951743,0.00014392754,0.000014235306,0.00008469819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006620688,0.0001878464,0.00016013453,0.00004172824,0.000041376028,0.000022382326,0.000063122716,0.00017817359,0.000013219734],"category_scores_gemma":[0.000064747386,0.00018122494,0.000033122014,0.00007326908,0.00007838602,0.0000046462783,0.00008457411,0.00012515513,0.000003880343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049411516,0.000026760816,0.002349894,0.00020551264,0.000028634244,0.000009029564,0.00007710843,0.00006583594,0.99603564,0.000010893957,0.00023554594,0.00090574566],"study_design_scores_gemma":[0.0003633363,0.00015942038,0.03320917,0.0000839903,0.000032926466,0.000049265847,0.00006951627,0.0011693955,0.96364677,0.00018637476,0.0007966829,0.00023316481],"about_ca_topic_score_codex":0.00003883923,"about_ca_topic_score_gemma":0.0000121559215,"teacher_disagreement_score":0.032388873,"about_ca_system_score_codex":0.000014197583,"about_ca_system_score_gemma":0.00003191522,"threshold_uncertainty_score":0.73901385},"labels":[],"label_agreement":null},{"id":"W4391542739","doi":"10.1101/gad.350740.123","title":"DNA damage remodels the MITF interactome to increase melanoma genomic instability","year":2024,"lang":"en","type":"article","venue":"Genes & Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Medical Research Council; Medical Research Council Canada; Fonds de Recherche du Québec - Santé; Marie Curie; Ludwig Institute for Cancer Research; Cancer Research Society; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Microphthalmia-associated transcription factor; Biology; Genome instability; DNA damage; DNA repair; Transcription factor; Genetics; Cell biology; Rad50; Cancer research; DNA; DNA-binding protein; Gene","score_opus":0.008415406925139004,"score_gpt":0.2776999010261688,"score_spread":0.26928449410102984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391542739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857691,0.002687082,0.009832049,0.00034800265,0.00040235894,0.00024730808,0.000010563661,0.000035136858,0.0006683784],"genre_scores_gemma":[0.9946468,0.00009850625,0.00400737,0.00035817394,0.00016016774,0.00006030004,0.000060452778,0.000028137567,0.0005801283],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989682,0.000030693445,0.00023457856,0.00039236233,0.00011564246,0.00025854592],"domain_scores_gemma":[0.9994322,0.000015617701,0.000014933002,0.00039091715,0.00003577072,0.00011054053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027720846,0.00017695581,0.000107273,0.00005183924,0.00008135471,0.000067685,0.00026607414,0.00006657352,0.000041584168],"category_scores_gemma":[0.00002586917,0.0001356937,0.000056930603,0.00011120577,0.000022956901,0.000003291433,0.00032516706,0.00007786632,0.00009727934],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042403084,0.000022151617,0.0007058552,0.000055167566,0.00009498691,0.000011212163,0.0008422661,0.00067821855,0.92533594,0.000033639044,0.0012461279,0.07093204],"study_design_scores_gemma":[0.000100433994,0.000054648917,0.024253435,0.000031053754,0.000012827991,0.000021348938,0.00009988913,0.00024677496,0.4770936,0.000028483375,0.4978033,0.0002541929],"about_ca_topic_score_codex":0.000021266475,"about_ca_topic_score_gemma":0.000101855876,"teacher_disagreement_score":0.49655718,"about_ca_system_score_codex":0.00005601337,"about_ca_system_score_gemma":0.00017735231,"threshold_uncertainty_score":0.5533428},"labels":[],"label_agreement":null},{"id":"W4391575341","doi":"10.1038/s41587-023-02106-x","title":"Efficient prime editing in two-cell mouse embryos using PEmbryo","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Rutgers Cancer Institute of New Jersey; National Institute of Biomedical Imaging and Bioengineering; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Searle Scholars Program; National Institute of Diabetes and Digestive and Kidney Diseases; Princeton University; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Indel; Biology; Embryo; Genetics; Computational biology; Genome; Genome editing; Phenotype; Prime (order theory); DNA; Cell biology; Molecular biology; Gene","score_opus":0.0037861849797879996,"score_gpt":0.29336834988515437,"score_spread":0.28958216490536637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391575341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9727597,0.013937695,0.01145225,0.00031618332,0.0008284018,0.00016763266,0.000011849325,0.00013769606,0.00038856614],"genre_scores_gemma":[0.9960576,0.00007476368,0.0030203238,0.00007592399,0.00038985268,0.000007278436,0.000021716745,0.00003891088,0.00031357587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885225,0.00001746097,0.00018826588,0.00049094635,0.00009660013,0.00035445378],"domain_scores_gemma":[0.99956185,0.000010513728,0.000025922385,0.0003390379,0.000023119399,0.00003958493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015711019,0.00018359572,0.0001448924,0.00024758885,0.000035743527,0.000023373797,0.00021070553,0.0008582549,0.0000089921505],"category_scores_gemma":[0.00006891357,0.00018241587,0.000071949944,0.00030668956,0.000060435126,0.0000012791802,0.00017350516,0.00076545344,0.000011834162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007784321,0.00002882431,0.0000673736,0.00004276316,0.0000129243745,0.000028966619,0.00001793129,0.0070272763,0.99056226,0.00030825267,0.00019234257,0.0017032942],"study_design_scores_gemma":[0.00029329723,0.000051909323,0.000039595365,0.000034163186,0.000010813553,0.00005672314,0.000058493017,0.030528082,0.95654213,0.000017618026,0.0121725965,0.00019459346],"about_ca_topic_score_codex":0.000015165637,"about_ca_topic_score_gemma":0.000025953697,"teacher_disagreement_score":0.034020152,"about_ca_system_score_codex":0.00003853979,"about_ca_system_score_gemma":0.000056523124,"threshold_uncertainty_score":0.7438703},"labels":[],"label_agreement":null},{"id":"W4391643076","doi":"10.1016/j.jip.2024.108072","title":"Development of a rapid visual detection technology for BmNPV based on CRISPR/Cas13a system","year":2024,"lang":"en","type":"article","venue":"Journal of Invertebrate Pathology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Jiangsu Provincial Key Research and Development Program","keywords":"Biology; CRISPR; Computational biology; Genetics; Gene","score_opus":0.008548099914673249,"score_gpt":0.2923345012934704,"score_spread":0.2837864013787971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391643076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5049376,0.0011436901,0.4928554,0.000097974626,0.0007663648,0.00011964092,0.000005400699,0.00001585202,0.000058051635],"genre_scores_gemma":[0.98612934,0.000029958199,0.013533339,0.00006200633,0.00017525976,0.000017590031,0.0000063041016,0.000024015377,0.000022175262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901634,0.000036641333,0.00048203277,0.00018540397,0.00009930314,0.00018025594],"domain_scores_gemma":[0.9994863,0.00002195217,0.00014821127,0.00012956023,0.00016488179,0.000049059847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043595585,0.00013681852,0.00024347361,0.00035786803,0.00003951286,0.0000102461645,0.00012602968,0.00023145173,0.0000056309655],"category_scores_gemma":[0.000079911995,0.00011711038,0.00013209428,0.00015240085,0.000043419463,0.0000033496506,0.000028667442,0.00013989283,0.0000038364333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001475546,0.000042211424,0.00005194489,0.00024879095,0.00006732422,0.000042710184,0.000052360723,0.0007123937,0.96433294,0.000093373,0.0002146682,0.033993714],"study_design_scores_gemma":[0.00057302054,0.0015376867,0.000078185476,0.00013189057,0.000039094128,0.0004110741,0.00022188244,0.023662698,0.9655277,0.00002416155,0.0076718996,0.00012071738],"about_ca_topic_score_codex":2.9440994e-7,"about_ca_topic_score_gemma":0.0000061347846,"teacher_disagreement_score":0.48119175,"about_ca_system_score_codex":0.000038805334,"about_ca_system_score_gemma":0.00018081229,"threshold_uncertainty_score":0.47756228},"labels":[],"label_agreement":null},{"id":"W4391650317","doi":"10.1177/09636625241227091","title":"Gene editing in animals: What does the public want to know and what information do stakeholder organizations provide?","year":2024,"lang":"en","type":"article","venue":"Public Understanding of Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Government of Canada; Ontario Genomics; Ontario Genomics Institute; Genome Canada","keywords":"Stakeholder; Public relations; Public engagement; Internet privacy; Psychology; Political science; Computer science","score_opus":0.027256239789286853,"score_gpt":0.2803478450636607,"score_spread":0.2530916052743738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391650317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82386804,0.0065590045,0.1490122,0.018847935,0.0010737011,0.00041162138,0.0000086044565,0.000037399637,0.00018153153],"genre_scores_gemma":[0.99805033,0.0012333746,0.0005205027,0.00009538115,0.00006544662,0.000009484726,0.0000070044252,0.000007327509,0.000011131572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990742,0.000013417728,0.00019329369,0.00022240556,0.0002349152,0.0002617269],"domain_scores_gemma":[0.99954873,0.000026144222,0.000034433095,0.0001702974,0.0001319487,0.00008841446],"candidate_categories":["scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.0008022786,0.000087047934,0.00006842853,0.0002826798,0.00020297237,0.0026756227,0.00023543791,0.00003842984,0.000007691663],"category_scores_gemma":[0.0004106691,0.000059665697,0.000013707773,0.0012227305,0.00030821288,0.0004959807,0.00018762099,0.0000650567,0.0000011441842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010565891,0.000046160243,0.0030932825,0.0003033082,0.00004447608,0.0000031905713,0.01957755,0.0010540484,0.83607876,0.052385677,0.00085830357,0.08654467],"study_design_scores_gemma":[0.0007465232,0.0003991147,0.002828265,0.0009779132,0.000033270717,0.00011951171,0.38914433,0.016542627,0.5038509,0.0040713614,0.08036019,0.00092600274],"about_ca_topic_score_codex":0.0000042930915,"about_ca_topic_score_gemma":0.00005748783,"teacher_disagreement_score":0.36956677,"about_ca_system_score_codex":0.000081235885,"about_ca_system_score_gemma":0.00022801348,"threshold_uncertainty_score":0.9983597},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"qualitative","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":["scholarly_communication"],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"split"},{"id":"W4391751836","doi":"10.1016/j.scr.2024.103344","title":"Generation and characterization of a human iPSC line and gene-corrected isogenic line derived from a patient with a CELF2 gene mutation","year":2024,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Toronto; Hotchkiss Brain Institute; Ontario Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Azrieli Foundation; Canada Research Chairs","keywords":"Biology; Induced pluripotent stem cell; CRISPR; Missense mutation; Germ layer; Gene; Genome editing; Genetics; Karyotype; Cas9; Mutation; Cell culture; Embryonic stem cell; Chromosome","score_opus":0.027536780753652984,"score_gpt":0.32369373237069476,"score_spread":0.2961569516170418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391751836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870744,0.0028535987,0.0096308375,0.00002699644,0.000048197988,0.0002827077,0.000049014907,0.00001174802,0.000022494583],"genre_scores_gemma":[0.99778414,0.00058671244,0.00044042946,0.000007303941,0.00016079095,0.000034943332,0.000785315,0.000024525181,0.00017586269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999104,0.00007088355,0.00017102419,0.00032297743,0.00017599411,0.00015509823],"domain_scores_gemma":[0.99959093,0.000015676133,0.0000281057,0.00015270751,0.00014948654,0.00006309731],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014800034,0.0001017304,0.000100390804,0.000099632685,0.00006858576,0.000051390787,0.00004374572,0.00008657968,0.000007853647],"category_scores_gemma":[0.0000050557196,0.00009056646,0.000018429306,0.00014471468,0.000046592584,0.0000055377504,0.000069093316,0.00009201932,0.0000011166802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048001984,0.000024208683,0.00012682089,0.00007444386,0.000030465355,0.000009188353,0.00051438616,0.00011193318,0.9857414,0.0000014834479,0.000008979873,0.013308739],"study_design_scores_gemma":[0.00029741062,0.0007675722,0.0017511752,0.000031257026,0.000016730806,0.000011713554,0.00008945074,0.012922205,0.98387265,0.0000035642913,0.00013911157,0.00009716616],"about_ca_topic_score_codex":0.000060376646,"about_ca_topic_score_gemma":0.00006877964,"teacher_disagreement_score":0.013211573,"about_ca_system_score_codex":0.000011669211,"about_ca_system_score_gemma":0.00005006052,"threshold_uncertainty_score":0.3693193},"labels":[],"label_agreement":null},{"id":"W4391810436","doi":"10.3390/siuj5010006","title":"“Pass the Genetic Scalpel”: A Comprehensive Review of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) in Urological Cancers","year":2024,"lang":"en","type":"review","venue":"Société Internationale d’Urologie Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; PTEN; Prostate cancer; Medicine; Bladder cancer; Cancer research; Cancer; Oncology; Bioinformatics; Internal medicine; Biology; PI3K/AKT/mTOR pathway; Gene; Apoptosis; Genetics","score_opus":0.05026840380366124,"score_gpt":0.414021065872569,"score_spread":0.3637526620689078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391810436","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016287724,0.9945301,0.00088286685,0.0006203115,0.0013228939,0.00071432546,0.00007585816,0.0000151391205,0.00020975196],"genre_scores_gemma":[0.0053479173,0.99251604,0.00027027781,0.0005934021,0.0006318924,0.00011398413,0.00015215094,0.000055213968,0.0003191146],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99678206,0.0004418971,0.0013307432,0.000614629,0.000416057,0.00041461413],"domain_scores_gemma":[0.998437,0.00015743557,0.0004796138,0.0005478535,0.000272392,0.00010570642],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006752689,0.0005284012,0.0012574957,0.00020338653,0.00006141608,0.00006751958,0.0011107514,0.0005028237,0.00007416531],"category_scores_gemma":[0.00040697935,0.0003543846,0.0011514606,0.00023557534,0.00020397981,0.0000066864286,0.00049760134,0.0012799357,0.0000083881105],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020818674,0.00017881954,0.00034639056,0.043872666,0.0041178036,0.0005603891,0.00020935781,0.0015506347,0.0007689935,0.000058043643,0.046070434,0.9020583],"study_design_scores_gemma":[0.00040173047,0.00044002818,0.0005022188,0.021285985,0.001109458,0.0019587297,0.00010531036,0.00020551344,0.000053312695,0.000121252844,0.97328615,0.00053029],"about_ca_topic_score_codex":0.000011221178,"about_ca_topic_score_gemma":0.000017009063,"teacher_disagreement_score":0.92721575,"about_ca_system_score_codex":0.0002568094,"about_ca_system_score_gemma":0.0005252612,"threshold_uncertainty_score":0.9998908},"labels":[],"label_agreement":null},{"id":"W4391970295","doi":"10.1038/s41421-023-00624-1","title":"Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes","year":2024,"lang":"en","type":"article","venue":"Cell Discovery","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Chinese Academy of Agricultural Sciences; China Postdoctoral Science Foundation; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Endogeny; Genome editing; Computational biology; DNA sequencing; DNA; Base (topology); Biology; Genome; Genomics; Base pair; genomic DNA; Computer science; Genetics; Gene","score_opus":0.015382852989433664,"score_gpt":0.2512635982122209,"score_spread":0.2358807452227872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391970295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9411408,0.0021745262,0.05454896,0.000023680675,0.00059528224,0.00014347295,0.00003981042,0.0000284395,0.001305081],"genre_scores_gemma":[0.99897885,0.00013080506,0.00018891224,0.000017488006,0.00028524463,0.000013998511,0.00011753797,0.000024933674,0.00024223853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916035,0.000032867953,0.0002331884,0.00026025766,0.0001334846,0.00017985907],"domain_scores_gemma":[0.99957544,0.00008990101,0.00008293288,0.00018841085,0.000028892788,0.000034430876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014611353,0.00015278236,0.00012154786,0.000035467918,0.00010416425,0.000089684545,0.00013911708,0.000078743615,0.0000041129706],"category_scores_gemma":[0.000102901846,0.000107485605,0.00012342878,0.00007792089,0.00005372383,0.000030650855,0.00010140104,0.00015404038,0.0000010699694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000039936162,0.000012381972,0.0038494759,0.00011232739,0.000037238267,0.0000028903507,0.0004159389,0.08427502,0.9100359,0.00007826723,0.00002184937,0.0011546899],"study_design_scores_gemma":[0.00010797906,0.000118286436,0.0004082755,0.00003177275,0.00004709318,0.0000051834645,0.001965213,0.043537084,0.9531156,0.00036356872,0.00015346853,0.00014649298],"about_ca_topic_score_codex":0.00003948161,"about_ca_topic_score_gemma":0.0000131303605,"teacher_disagreement_score":0.057838093,"about_ca_system_score_codex":0.0000138077,"about_ca_system_score_gemma":0.00006143154,"threshold_uncertainty_score":0.43831357},"labels":[],"label_agreement":null},{"id":"W4392058892","doi":"10.12688/gatesopenres.15323.1","title":"Taking stock: Is gene drive research delivering on its principles?","year":2024,"lang":"en","type":"preprint","venue":"Gates Open Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; McMaster University","funders":"McMaster University; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Accountability; Transparency (behavior); Gene drive; Political science; Engineering ethics; Public relations; Biotechnology; Engineering; Gene; Biology; Law; Genetics","score_opus":0.2693152094924604,"score_gpt":0.520938433301307,"score_spread":0.25162322380884655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392058892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93924373,0.010548614,0.00021090775,0.001233202,0.0005984124,0.0030561646,0.00022110662,0.000047150654,0.044840686],"genre_scores_gemma":[0.98108155,0.0025678254,0.0011903794,0.000069490896,0.0009398644,0.00073441956,0.00024821077,0.0001674266,0.013000825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9947235,0.00043662454,0.00043278967,0.0017841784,0.0013053908,0.0013174929],"domain_scores_gemma":[0.9968954,0.0001362591,0.00007270146,0.0016203419,0.00096914964,0.00030618202],"candidate_categories":["metaepi_narrow","open_science","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004510673,0.000408404,0.0003824056,0.0005356321,0.00042688282,0.001013639,0.00269329,0.00064790895,0.00030687614],"category_scores_gemma":[0.0006878955,0.00040686215,0.00017519192,0.00047494122,0.00018116622,0.0000048055563,0.022068657,0.0031821027,0.0005883809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039288876,0.00020512924,0.00044603035,0.0014722103,0.0006326441,0.0002679135,0.0012906304,0.015843743,0.93683356,0.0014641539,0.022760497,0.01839062],"study_design_scores_gemma":[0.00036014052,0.0005244526,0.0011431343,0.000960533,0.000018248087,0.000016774891,0.00021720615,0.006006305,0.9242806,0.00090807985,0.06495982,0.0006047548],"about_ca_topic_score_codex":0.0006139183,"about_ca_topic_score_gemma":0.00014428544,"teacher_disagreement_score":0.042199317,"about_ca_system_score_codex":0.0002021279,"about_ca_system_score_gemma":0.0007132131,"threshold_uncertainty_score":0.99983835},"labels":[],"label_agreement":null},{"id":"W4392159460","doi":"10.1038/s41525-024-00397-w","title":"DNA and RNA base editors can correct the majority of pathogenic single nucleotide variants","year":2024,"lang":"en","type":"article","venue":"npj Genomic Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Israel Science Foundation; National Institutes of Health; Foundation Fighting Blindness","keywords":"Genetics; RNA; DNA; Nucleotide; Base (topology); Biology; Computational biology; Base pair; Gene; Mathematics","score_opus":0.007698780476835962,"score_gpt":0.25232815451697493,"score_spread":0.24462937404013896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392159460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841278,0.008267161,0.0017247391,0.0008436319,0.0040906477,0.00014524948,0.00003377053,0.000015085538,0.0007518816],"genre_scores_gemma":[0.9946848,0.00042427602,0.000098646364,0.00012843948,0.0042807404,0.0000047678013,0.000028949671,0.000021491835,0.00032785616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927866,0.000029393934,0.00019199225,0.00024168889,0.0000981731,0.00016006026],"domain_scores_gemma":[0.999559,0.000041247953,0.000029969684,0.00026645852,0.000025812878,0.00007750733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029186363,0.00012311482,0.00014595313,0.000036735546,0.000037632355,0.000008413551,0.00011763397,0.00006816625,0.00004864863],"category_scores_gemma":[0.00008885394,0.00008512116,0.00004069493,0.00007348223,0.000115570154,0.0000011949415,0.000069096284,0.00009097158,0.0000026542355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012314155,0.00000902875,0.00012741756,0.00005632291,0.000044209166,0.000008255452,0.0002638715,0.000023726645,0.9816801,0.000013184821,0.0108816605,0.0068799295],"study_design_scores_gemma":[0.0012039555,0.0010494614,0.009311307,0.00025472222,0.0003020784,0.00017122732,0.00078269036,0.0017442167,0.82102543,0.00019896588,0.16352683,0.00042911016],"about_ca_topic_score_codex":0.0000795864,"about_ca_topic_score_gemma":0.00004241515,"teacher_disagreement_score":0.16065463,"about_ca_system_score_codex":0.0000136783265,"about_ca_system_score_gemma":0.000049679027,"threshold_uncertainty_score":0.34711403},"labels":[],"label_agreement":null},{"id":"W4392165316","doi":"10.1002/dta.3664","title":"Gene doping detection in the era of genomics","year":2024,"lang":"en","type":"review","venue":"Drug Testing and Analysis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Shanghai University of Sport; Shanghai Jiao Tong University; World Anti-Doping Agency","keywords":"Genomics; Computational biology; Gene; Biology; Computer science; Genetics; Genome","score_opus":0.01794789504540043,"score_gpt":0.315297370631001,"score_spread":0.29734947558560054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392165316","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00620403,0.9925495,0.0010585748,0.000004973763,0.0000319804,0.0000761135,0.000013131942,0.000005650348,0.00005606398],"genre_scores_gemma":[0.025438033,0.9735455,0.000771801,0.000006261406,0.00012159236,0.000014079785,0.00006152861,0.0000148772815,0.000026335107],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992959,0.000047170928,0.00026473415,0.00023716055,0.00005386337,0.00010118002],"domain_scores_gemma":[0.9996346,0.000051731156,0.00007723761,0.0002023218,0.000017466413,0.000016595244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028637212,0.00014529967,0.0004060287,0.00013358143,0.000028249468,0.000025248923,0.00010961675,0.0000832527,4.789326e-7],"category_scores_gemma":[0.00008391405,0.000100667385,0.00023701387,0.00066099694,0.00001770657,5.8647845e-7,0.000056485173,0.00018604613,6.229399e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[4.211482e-7,0.0000060035472,0.0000418212,0.0019264932,0.00040887436,0.000002649284,0.00006292204,0.00041550657,0.00096275145,6.958647e-7,0.000007903724,0.99616396],"study_design_scores_gemma":[0.0006276527,0.00028240308,0.0008529841,0.012678946,0.07382703,0.00037948682,0.0007607577,0.02751843,0.014304982,0.00016055652,0.8656615,0.0029452497],"about_ca_topic_score_codex":0.000068468646,"about_ca_topic_score_gemma":0.000063290216,"teacher_disagreement_score":0.9932187,"about_ca_system_score_codex":0.000007845092,"about_ca_system_score_gemma":0.000033098677,"threshold_uncertainty_score":0.41050968},"labels":[],"label_agreement":null},{"id":"W4392374358","doi":"10.1101/2024.03.01.582837","title":"Nonlinear transcriptional responses to gradual modulation of transcription factor dosage","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Human Genome Research Institute; Science for Life Laboratory; Knut och Alice Wallenbergs Stiftelse; Canadian Institutes of Health Research; European Commission","keywords":"Transcription factor; Modulation (music); Transcription (linguistics); Biology; Genetics; Physics; Gene","score_opus":0.014901895845027427,"score_gpt":0.26605621357866344,"score_spread":0.251154317733636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392374358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97274154,0.0020445779,0.022125496,0.00017266312,0.0011123742,0.0004845779,0.0012250702,0.00009012823,0.0000035964679],"genre_scores_gemma":[0.9920106,0.0001927642,0.0068992143,0.0000572703,0.00062527024,0.00008115872,0.000005806606,0.000106311476,0.000021592925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980846,0.000066352986,0.0004721843,0.00076280936,0.00030603952,0.00030799533],"domain_scores_gemma":[0.9988237,0.000011571257,0.00009417955,0.0006512512,0.00024100677,0.00017829383],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023673235,0.00040016352,0.00033042816,0.00025559118,0.00004586246,0.00006332633,0.0002763586,0.00046332425,0.000020207699],"category_scores_gemma":[0.000076071425,0.00044907053,0.00024158046,0.00022734753,0.00005065893,0.000005160945,0.00016571519,0.00034361068,0.00001724496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012804955,0.00006876153,0.00032268272,0.00042835096,0.00012790982,0.000005408468,0.000023803805,0.0015301802,0.99717194,0.00008193476,0.000103838785,0.0000071248446],"study_design_scores_gemma":[0.0002746536,0.0001671102,0.05010269,0.00021960743,0.00008213036,3.3132512e-8,0.0000025478614,0.0011431195,0.9427919,0.0000033489723,0.0047212816,0.0004916259],"about_ca_topic_score_codex":0.000020029234,"about_ca_topic_score_gemma":0.0000047157,"teacher_disagreement_score":0.054380104,"about_ca_system_score_codex":0.00006102856,"about_ca_system_score_gemma":0.00028297576,"threshold_uncertainty_score":0.9997961},"labels":[],"label_agreement":null},{"id":"W4392391188","doi":"10.1016/j.omtm.2024.101227","title":"Manufacturing DNA in E. coli yields higher-fidelity DNA than in vitro enzymatic synthesis","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; Blutip (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNA; Fidelity; Enzyme; DNA replication; Replication (statistics); Computational biology; Chemistry; Biology; Biochemistry; Computer science; Virology","score_opus":0.0434665003881973,"score_gpt":0.41848856131846546,"score_spread":0.37502206093026813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392391188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8764484,0.0049063745,0.1168956,0.0003912677,0.0006513772,0.00037713686,0.0000034610557,0.00004625403,0.00028011948],"genre_scores_gemma":[0.82485265,0.0008485766,0.1733166,0.00045745514,0.00010144095,0.00017331429,0.000022966173,0.00006053423,0.00016644524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966323,0.0007300101,0.0010853423,0.0008131411,0.00023006012,0.00050914567],"domain_scores_gemma":[0.99886346,0.00038191208,0.00006739762,0.0005117033,0.000022312823,0.00015324526],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0032452964,0.00035902497,0.0005092701,0.00016839393,0.000039141956,0.00006455763,0.00034969603,0.0003909938,0.000054472603],"category_scores_gemma":[0.00026649365,0.00033807347,0.0002468124,0.00021936347,0.000058824637,0.000006074593,0.0001686581,0.00040085238,0.000017769591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015054508,0.00013676574,0.00032399088,0.0000834012,0.0001621055,0.00008559017,0.0001364953,0.0001753674,0.71965843,0.00002721894,0.000035733185,0.27902436],"study_design_scores_gemma":[0.00046081978,0.000064909545,0.026507623,0.00012737085,0.000012723635,0.0000046251753,0.000024647148,0.00023244704,0.93498695,0.0004075062,0.036764607,0.00040574942],"about_ca_topic_score_codex":0.000022506669,"about_ca_topic_score_gemma":0.000022577262,"teacher_disagreement_score":0.2786186,"about_ca_system_score_codex":0.000077285134,"about_ca_system_score_gemma":0.00018265608,"threshold_uncertainty_score":0.99990714},"labels":[],"label_agreement":null},{"id":"W4392470276","doi":"10.54254/2753-8818/32/20240779","title":"Unveiling the evolutionary significance: Atavism’s transition from ancestral traits to a fundamental biological phenomenon","year":2024,"lang":"en","type":"article","venue":"Theoretical and Natural Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Phenomenon; Transition (genetics); Adaptation (eye); Epistemology; Biology; Philosophy; Gene; Genetics; Neuroscience","score_opus":0.006657902040069742,"score_gpt":0.2855998730665112,"score_spread":0.27894197102644147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392470276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893121,0.0037849091,0.0052491883,0.0010235123,0.00021514522,0.00012771247,0.000033258933,0.00002209106,0.00023206051],"genre_scores_gemma":[0.9986383,0.00009718213,0.0006894357,0.0002725849,0.0002491231,0.0000092054825,0.000017260809,0.000004347648,0.000022568845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915504,0.000020717252,0.00009197605,0.0003583875,0.00014008161,0.00023382125],"domain_scores_gemma":[0.9997591,0.000034541972,0.000005666693,0.00007953753,0.000017260034,0.000103897495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020182392,0.00009697993,0.00006459809,0.000022002243,0.00014810693,0.00006784763,0.00017260651,0.000044289234,0.000049402282],"category_scores_gemma":[0.000029829558,0.000057393336,0.000033572658,0.00020242928,0.0008694898,0.000007801978,0.000065539534,0.00011326686,0.000008666628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052328247,0.000009585489,0.000025901543,0.000004754118,0.0000057345824,0.000002540012,0.00021695693,0.00009052999,0.9691975,0.02111272,0.000051637213,0.009229798],"study_design_scores_gemma":[0.0010185199,0.0023823425,0.16091497,0.0002766497,0.00009276103,0.00016711437,0.0020612872,0.051878087,0.6918064,0.06484131,0.02288081,0.0016797702],"about_ca_topic_score_codex":0.000006937186,"about_ca_topic_score_gemma":0.0000012853404,"teacher_disagreement_score":0.27739114,"about_ca_system_score_codex":0.000015031756,"about_ca_system_score_gemma":0.000044476703,"threshold_uncertainty_score":0.32036713},"labels":[],"label_agreement":null},{"id":"W4392578137","doi":"10.1101/2024.03.07.583774","title":"Efficient and multiplexed somatic genome editing with Cas12a mice","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Stanford Cancer Institute; Tobacco-Related Disease Research Program; National Institutes of Health; National Science Foundation","keywords":"Trans-activating crRNA; Biology; Somatic cell; Genome editing; CRISPR; Genome; Computational biology; Genetics; Gene","score_opus":0.005482187515996429,"score_gpt":0.22220152961787226,"score_spread":0.21671934210187582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392578137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890602,0.0061843432,0.0032971343,0.00007753077,0.00060107914,0.000496782,0.00013464688,0.0001354455,0.000012807108],"genre_scores_gemma":[0.9910066,0.00015931184,0.0076376707,0.000055180168,0.00086719706,0.00011447729,0.000001330639,0.00014982562,0.000008423463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979986,0.000037368667,0.0003276408,0.0009638245,0.00021344807,0.0004590987],"domain_scores_gemma":[0.9987668,0.000016049966,0.0001285167,0.00071785226,0.00015819282,0.00021262195],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002581344,0.0004964584,0.00034894008,0.00015027447,0.000093516646,0.0001611946,0.00024855885,0.00037834642,0.0000056810204],"category_scores_gemma":[0.00007908748,0.00048138254,0.00008943501,0.00017585381,0.000090975926,0.0000015659837,0.0007485426,0.0004583358,0.000016635704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015861973,0.000032915537,0.00041133235,0.00083779177,0.00017190936,0.000042640862,0.00001872529,0.006284412,0.99212915,0.000016246586,0.000037082704,0.000001926775],"study_design_scores_gemma":[0.0007255382,0.00015897806,0.017598335,0.0007102343,0.00029179975,4.88802e-7,0.00002151474,0.010282197,0.96559435,8.4602266e-7,0.0033698294,0.0012459051],"about_ca_topic_score_codex":0.000025374798,"about_ca_topic_score_gemma":0.0000062003764,"teacher_disagreement_score":0.02653482,"about_ca_system_score_codex":0.000051740804,"about_ca_system_score_gemma":0.00019403822,"threshold_uncertainty_score":0.9997638},"labels":[],"label_agreement":null},{"id":"W4392689980","doi":"10.1158/1940-6207.c.6543832","title":"Data from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Genetics; Biology; Gene","score_opus":0.019881902511572284,"score_gpt":0.26854216410522846,"score_spread":0.24866026159365617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392689980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9406477,0.0041957498,0.039104767,0.00025124126,0.0021353033,0.001646495,0.0099293385,0.00013422332,0.0019551695],"genre_scores_gemma":[0.96799797,0.00085496105,0.00503154,0.00025583335,0.0005231815,0.00017267924,0.024171634,0.00019038416,0.00080184435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.993784,0.0004121604,0.0013676237,0.0025037413,0.0006514924,0.0012809928],"domain_scores_gemma":[0.99566364,0.00018865647,0.00032729976,0.002910297,0.00016833421,0.0007417577],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008213022,0.001159122,0.0012674654,0.0004715598,0.00014523137,0.00016882973,0.0021394633,0.0018666056,0.00058086525],"category_scores_gemma":[0.00021642049,0.0011986913,0.00049196207,0.00033492572,0.00023823167,0.000025343126,0.0010917506,0.0007745491,0.00006690433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012920068,0.00009781274,0.00026502545,0.00017344762,0.0007069403,0.00038844772,0.00046934144,0.017476082,0.9719255,0.000021585274,0.0067832232,0.0015633971],"study_design_scores_gemma":[0.017066587,0.0031172363,0.24309412,0.0014213236,0.0025696415,0.00012885296,0.0003002154,0.050547827,0.51389664,0.0020489562,0.15553966,0.010268926],"about_ca_topic_score_codex":0.053490933,"about_ca_topic_score_gemma":0.5765552,"teacher_disagreement_score":0.52306426,"about_ca_system_score_codex":0.0002025751,"about_ca_system_score_gemma":0.00076634274,"threshold_uncertainty_score":0.99942917},"labels":[],"label_agreement":null},{"id":"W4392721932","doi":"10.1158/1940-6207.c.6543832.v1","title":"Data from Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a &lt;i&gt;BRCA1&lt;/i&gt;/&lt;i&gt;2&lt;/i&gt; French Canadian Founder Mutation","year":2023,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Allele; Genetics; Biology; Molecular biology; Internal medicine; Medicine; Gene","score_opus":0.019881902511572284,"score_gpt":0.26854216410522846,"score_spread":0.24866026159365617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392721932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9406477,0.0041957498,0.039104767,0.00025124126,0.0021353033,0.001646495,0.0099293385,0.00013422332,0.0019551695],"genre_scores_gemma":[0.96799797,0.00085496105,0.00503154,0.00025583335,0.0005231815,0.00017267924,0.024171634,0.00019038416,0.00080184435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.993784,0.0004121604,0.0013676237,0.0025037413,0.0006514924,0.0012809928],"domain_scores_gemma":[0.99566364,0.00018865647,0.00032729976,0.002910297,0.00016833421,0.0007417577],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008213022,0.001159122,0.0012674654,0.0004715598,0.00014523137,0.00016882973,0.0021394633,0.0018666056,0.00058086525],"category_scores_gemma":[0.00021642049,0.0011986913,0.00049196207,0.00033492572,0.00023823167,0.000025343126,0.0010917506,0.0007745491,0.00006690433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012920068,0.00009781274,0.00026502545,0.00017344762,0.0007069403,0.00038844772,0.00046934144,0.017476082,0.9719255,0.000021585274,0.0067832232,0.0015633971],"study_design_scores_gemma":[0.017066587,0.0031172363,0.24309412,0.0014213236,0.0025696415,0.00012885296,0.0003002154,0.050547827,0.51389664,0.0020489562,0.15553966,0.010268926],"about_ca_topic_score_codex":0.053490933,"about_ca_topic_score_gemma":0.5765552,"teacher_disagreement_score":0.52306426,"about_ca_system_score_codex":0.0002025751,"about_ca_system_score_gemma":0.00076634274,"threshold_uncertainty_score":0.99942917},"labels":[],"label_agreement":null},{"id":"W4392746654","doi":"10.7554/elife.95151","title":"Un1Cas12f1 and Cas9 gene drive in HSV1: viruses that ‘infect’ viruses","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"CRISPR; Cas9; Gene; Biology; Genome editing; Gene drive; Genetics; Computational biology; Virology; Function (biology)","score_opus":0.020572653711078404,"score_gpt":0.32967650092171596,"score_spread":0.30910384721063755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392746654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97212565,0.025417851,0.0005778923,0.000074491,0.0007505671,0.00024739542,0.000121294834,0.00004272478,0.0006421173],"genre_scores_gemma":[0.9941335,0.0039265426,0.00050410366,0.00050373864,0.00054519536,0.00004111075,0.00007429159,0.00006579262,0.00020575874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986377,0.00002533514,0.000240759,0.0006557592,0.00015674254,0.00028373848],"domain_scores_gemma":[0.9993438,0.00001725148,0.00005072872,0.0004509057,0.000034317723,0.00010297877],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015449384,0.0003335599,0.00027885207,0.00011993535,0.000028789384,0.00007578448,0.00017749255,0.00040595746,0.000019798124],"category_scores_gemma":[0.000060397924,0.00033557822,0.00011163625,0.00006360369,0.000058678364,0.0000014050029,0.0011795019,0.00040097212,0.000026711026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050553037,0.00006535707,0.013257917,0.0005943819,0.00028136172,0.0001379973,0.00052454637,0.004062356,0.9720725,0.00007265164,0.005289668,0.0035907545],"study_design_scores_gemma":[0.0003115696,0.00006718253,0.007859701,0.00017820025,0.000058201193,0.000034190427,0.00007216841,0.00021995572,0.952114,0.00022223957,0.03830547,0.00055712473],"about_ca_topic_score_codex":0.0002087825,"about_ca_topic_score_gemma":0.00043782574,"teacher_disagreement_score":0.0330158,"about_ca_system_score_codex":0.000023348815,"about_ca_system_score_gemma":0.000103237595,"threshold_uncertainty_score":0.99990964},"labels":[],"label_agreement":null},{"id":"W4392746665","doi":"10.7554/elife.95151.1","title":"Un1Cas12f1 and Cas9 gene drive in HSV1: viruses that ‘infect’ viruses","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"CRISPR; Cas9; Gene; Biology; Genome editing; Gene drive; Virology; Computational biology; Genetics; Function (biology); Phenotype","score_opus":0.020572653711078404,"score_gpt":0.32967650092171596,"score_spread":0.30910384721063755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392746665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97212565,0.025417851,0.0005778923,0.000074491,0.0007505671,0.00024739542,0.000121294834,0.00004272478,0.0006421173],"genre_scores_gemma":[0.9941335,0.0039265426,0.00050410366,0.00050373864,0.00054519536,0.00004111075,0.00007429159,0.00006579262,0.00020575874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986377,0.00002533514,0.000240759,0.0006557592,0.00015674254,0.00028373848],"domain_scores_gemma":[0.9993438,0.00001725148,0.00005072872,0.0004509057,0.000034317723,0.00010297877],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015449384,0.0003335599,0.00027885207,0.00011993535,0.000028789384,0.00007578448,0.00017749255,0.00040595746,0.000019798124],"category_scores_gemma":[0.000060397924,0.00033557822,0.00011163625,0.00006360369,0.000058678364,0.0000014050029,0.0011795019,0.00040097212,0.000026711026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050553037,0.00006535707,0.013257917,0.0005943819,0.00028136172,0.0001379973,0.00052454637,0.004062356,0.9720725,0.00007265164,0.005289668,0.0035907545],"study_design_scores_gemma":[0.0003115696,0.00006718253,0.007859701,0.00017820025,0.000058201193,0.000034190427,0.00007216841,0.00021995572,0.952114,0.00022223957,0.03830547,0.00055712473],"about_ca_topic_score_codex":0.0002087825,"about_ca_topic_score_gemma":0.00043782574,"teacher_disagreement_score":0.0330158,"about_ca_system_score_codex":0.000023348815,"about_ca_system_score_gemma":0.000103237595,"threshold_uncertainty_score":0.99990964},"labels":[],"label_agreement":null},{"id":"W4392753286","doi":"10.21203/rs.3.rs-4000095/v1","title":"Capsule coffee-inspired customizable production of nucleic acid medicine using a rapid on-site microfluidic assembly (ROMA) technology","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Biotech (Canada)","funders":"","keywords":"Nucleic acid; Microfluidics; Production (economics); Capsule; Nanotechnology; Chemistry; Biology; Materials science; Biochemistry; Botany","score_opus":0.03372506290603896,"score_gpt":0.38849969965077713,"score_spread":0.3547746367447382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392753286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.944536,0.0512009,0.0004623994,0.0010532355,0.0009429583,0.0009690101,0.00007596364,0.00007701315,0.00068253116],"genre_scores_gemma":[0.9930494,0.004520831,0.0005200054,0.000013534918,0.000818399,0.000097447824,0.00023473453,0.000104239014,0.0006414445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971547,0.00016508416,0.0004448932,0.0010275561,0.0005876332,0.00062013016],"domain_scores_gemma":[0.99800575,0.000017500604,0.000101778925,0.0012113196,0.0005368869,0.00012679552],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010970547,0.00035106682,0.00048510171,0.00092269015,0.00012687968,0.00003292524,0.00045749353,0.0007408891,0.000046401252],"category_scores_gemma":[0.00051269436,0.00033034498,0.00016139683,0.00065767195,0.00037057546,0.0000023044772,0.0013276158,0.0011395701,0.00003445329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007982386,0.00007549076,0.000056421246,0.0017066785,0.00013688703,0.000022137396,0.00012208351,0.001116039,0.98311627,0.000049898248,0.0117056,0.0018126564],"study_design_scores_gemma":[0.00039867367,0.00072256016,0.00009954234,0.0016536951,0.00005591005,0.000036958932,0.00024695962,0.00060164905,0.9869622,0.0003055993,0.008629575,0.00028666074],"about_ca_topic_score_codex":0.00014513338,"about_ca_topic_score_gemma":0.000015382897,"teacher_disagreement_score":0.048513375,"about_ca_system_score_codex":0.0001300702,"about_ca_system_score_gemma":0.0003930758,"threshold_uncertainty_score":0.9999149},"labels":[],"label_agreement":null},{"id":"W4392831327","doi":"10.5376/mpb.2024.15.0003","title":"Breeding 4.0 The Breeding Revolution of Genetic Information Integration and Editing","year":2024,"lang":"en","type":"article","venue":"Molecular Plant Breeding","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Genome editing; Animal breeding; Selective breeding; Pig breeding; Genetics; Genome; Gene","score_opus":0.00681603034750707,"score_gpt":0.23629663042411353,"score_spread":0.22948060007660645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392831327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69249684,0.0035570692,0.30234945,0.00021508304,0.0005076724,0.00018065496,0.000028134487,0.00003961511,0.0006254851],"genre_scores_gemma":[0.99747837,0.00023264968,0.0017183403,0.00005728584,0.00036586047,0.000012677843,0.000100156765,0.000017807022,0.000016861926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990923,0.000019461879,0.0003031157,0.00019656341,0.0001870567,0.00020152869],"domain_scores_gemma":[0.9996676,0.000023329589,0.00006712298,0.00013626464,0.000060468086,0.000045209563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033194575,0.00015041532,0.0001116222,0.00011979631,0.000095166026,0.000106019696,0.00011775082,0.00010659023,0.000003135315],"category_scores_gemma":[0.000120477474,0.00012544307,0.000066449,0.00016236937,0.000048863596,0.000025647701,0.00010114596,0.00013943302,0.000002175921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000884693,0.0000027833069,0.00036913028,0.00011561818,0.00003807684,0.000003821105,0.00032723907,0.00087768503,0.9785731,0.0006722567,0.0006351351,0.01837634],"study_design_scores_gemma":[0.00037816944,0.00045005622,0.003478342,0.00072210573,0.00013208833,0.00055357715,0.0013654613,0.09365541,0.8876906,0.00021971624,0.010916815,0.0004376809],"about_ca_topic_score_codex":0.000034642737,"about_ca_topic_score_gemma":0.000007657295,"teacher_disagreement_score":0.30498153,"about_ca_system_score_codex":0.000018115523,"about_ca_system_score_gemma":0.000022337228,"threshold_uncertainty_score":0.51154196},"labels":[],"label_agreement":null},{"id":"W4392923527","doi":"10.1101/2024.03.17.585235","title":"CROPseq-multi: a universal solution for multiplexed perturbation in high-content pooled CRISPR screens","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Broad Institute; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Decoding methods; Multiplexing; Computer science; Computational biology; Biology; Algorithm; Genetics; Telecommunications; Gene","score_opus":0.018234167293527566,"score_gpt":0.2553809113003262,"score_spread":0.23714674400679864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392923527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86510545,0.0034921959,0.12763086,0.00027641602,0.0014951109,0.0013681648,0.00047059887,0.00015810877,0.0000030811539],"genre_scores_gemma":[0.9759664,0.00018519151,0.022772022,0.00009560922,0.0004993283,0.00027548333,0.000010921689,0.00013886574,0.00005617078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977528,0.00006076965,0.00045424933,0.0010358116,0.00017840414,0.00051797956],"domain_scores_gemma":[0.99863863,0.000019243344,0.00014316755,0.0007145257,0.00032856542,0.00015586252],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034365355,0.00048932555,0.00038763322,0.0002615603,0.0000790358,0.00010293187,0.0003194059,0.0006816834,0.000005810689],"category_scores_gemma":[0.00023262523,0.00055327866,0.0002250237,0.00019695672,0.000060221548,0.0000070698293,0.00048653196,0.00043845348,0.0000103763505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011110863,0.000091645394,0.0006741616,0.00033760854,0.00015691409,0.0000127407475,0.000012117658,0.001706881,0.9962303,0.00024035427,0.00041825685,0.00000793111],"study_design_scores_gemma":[0.0021119616,0.00016671841,0.036632802,0.00039827803,0.00020605914,3.9442284e-8,0.000013474602,0.0341019,0.92176026,0.0000046941577,0.0036097327,0.0009940864],"about_ca_topic_score_codex":0.0002325438,"about_ca_topic_score_gemma":0.000091368696,"teacher_disagreement_score":0.11086095,"about_ca_system_score_codex":0.00020837547,"about_ca_system_score_gemma":0.00031673547,"threshold_uncertainty_score":0.99969184},"labels":[],"label_agreement":null},{"id":"W4392956976","doi":"10.1007/978-1-0716-3746-3_8","title":"Generation of Knockout Mouse Trophoblast Stem Cells by CRISPR/Cas9","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Alberta Children's Hospital","funders":"","keywords":"Placentation; Trophoblast; CRISPR; Biology; Genome editing; Cas9; Placenta; Stem cell; Cell biology; Gene knockout; Genetics; Gene; Fetus; Pregnancy","score_opus":0.02077154445257113,"score_gpt":0.40430729924948083,"score_spread":0.3835357547969097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392956976","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20358957,0.009105475,0.78656846,0.000037019894,0.0003911745,0.00013374024,0.00003492064,0.000016697744,0.0001229668],"genre_scores_gemma":[0.56099045,0.00085141364,0.43630227,0.00018566802,0.00021731562,0.00006754126,0.00016580104,0.00008538363,0.0011341486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984969,0.00035949892,0.00034424264,0.00047287336,0.000059999362,0.00026646873],"domain_scores_gemma":[0.99949014,0.000031536096,0.00004058273,0.00034694868,0.000037127353,0.000053657317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049757055,0.00019407253,0.00023872069,0.00012044348,0.000017537142,0.000015541122,0.00018175018,0.0002793125,0.000018126451],"category_scores_gemma":[0.000036405072,0.00018976926,0.00011876328,0.00016958186,0.00007301151,0.0000019548743,0.00010073282,0.00014169226,0.0000044396616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011977145,0.000026017155,0.000036206504,0.0000459171,0.00004584436,0.000006142106,0.0000379987,0.0009466832,0.9797754,0.0002169355,0.00082558667,0.018025242],"study_design_scores_gemma":[0.00018930016,0.00021770564,0.000004883918,0.000010899969,0.000016293076,0.000008666619,0.000024225388,0.0026137242,0.9688061,0.00006343492,0.027859682,0.00018511013],"about_ca_topic_score_codex":0.000019403662,"about_ca_topic_score_gemma":0.0000073369138,"teacher_disagreement_score":0.3574009,"about_ca_system_score_codex":0.000017771341,"about_ca_system_score_gemma":0.000040056668,"threshold_uncertainty_score":0.7738565},"labels":[],"label_agreement":null},{"id":"W4392966922","doi":"10.3389/fpls.2024.1346364","title":"Efficient induction and rapid identification of haploid grains in tetraploid wheat by editing genes TtMTL and pyramiding anthocyanin markers","year":2024,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Chinese Academy of Agricultural Sciences; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Institute of Crop Sciences, Chinese Academy of Agricultural Sciences; Chinese Academy of Sciences","keywords":"Biology; Ploidy; Endosperm; Doubled haploidy; Embryo; Mutant; Genetics; Chromosome; Gene; Embryo rescue","score_opus":0.004784470061726084,"score_gpt":0.24383740410141624,"score_spread":0.23905293403969016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392966922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97342616,0.0098888315,0.015739867,0.000045950415,0.00073315034,0.00010117732,0.000027040403,0.000007816084,0.000030023108],"genre_scores_gemma":[0.99778247,0.0010388618,0.0010866055,0.0000060814937,0.000042164782,0.0000057629777,0.00001584184,0.0000063180505,0.000015882775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991879,0.000012914794,0.00017021065,0.00033218245,0.0001239819,0.00017283304],"domain_scores_gemma":[0.99982643,0.000008026391,0.000029249813,0.00008776324,0.000014226609,0.000034290715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006138975,0.00008070688,0.00008714295,0.00024560586,0.00004845361,0.000048042184,0.00008665834,0.000053016825,4.2945646e-7],"category_scores_gemma":[0.00006457566,0.000081775615,0.000012158219,0.00031083619,0.00021807887,0.000010663798,0.000049459537,0.00006822227,9.089662e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009568638,0.000008667845,0.008731291,0.000057340025,0.0000032206876,0.0000016861709,0.0001718983,0.0010402413,0.9807791,0.000015725902,0.00037583453,0.008805402],"study_design_scores_gemma":[0.0002129903,0.00006517168,0.019332714,0.00014255666,0.000007711922,0.000032949913,0.0013763738,0.120437,0.85717815,0.000032886604,0.000998139,0.00018335185],"about_ca_topic_score_codex":0.000018829849,"about_ca_topic_score_gemma":0.000009271285,"teacher_disagreement_score":0.123600975,"about_ca_system_score_codex":0.000023597666,"about_ca_system_score_gemma":0.000029195333,"threshold_uncertainty_score":0.3334713},"labels":[],"label_agreement":null},{"id":"W4392968913","doi":"10.1093/nar/gkae174","title":"Expanding the flexibility of base editing for high-throughput genetic screens in bacteria","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"H2020 European Research Council; National Institutes of Health; National Institute of General Medical Sciences; Bayerisches Staatsministerium für Wissenschaft und Kunst","keywords":"Biology; CRISPR; Cas9; Genome editing; Computational biology; Genetic screen; Bacterial genome size; Synthetic biology; Genetics; Flexibility (engineering); Genome; Gene; Phenotype","score_opus":0.044699163737893385,"score_gpt":0.40025003111034824,"score_spread":0.35555086737245484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392968913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98364735,0.0013523941,0.013741462,0.00034229615,0.00022220715,0.00039285768,0.000043900982,0.000013498565,0.00024405176],"genre_scores_gemma":[0.9946642,0.00012107294,0.004300207,0.000016041444,0.00057901477,0.00007000455,0.000031210948,0.000031393178,0.0001868767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998659,0.00009712768,0.00024549416,0.00037487532,0.0002261953,0.00039726586],"domain_scores_gemma":[0.99928176,0.00013232304,0.000015881911,0.0004134306,0.00010394652,0.000052673135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001306715,0.00010553702,0.00012499122,0.00009960937,0.000086921624,0.000050552204,0.0002662885,0.00011162021,0.000051174742],"category_scores_gemma":[0.00034995956,0.000083580046,0.00007267684,0.00026132422,0.00014785619,0.0000044571416,0.00020303701,0.00020815698,0.0000054853435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005423271,0.000027178241,0.0011780907,0.0002233476,0.000026977366,0.0000044782537,0.00022667821,0.0005053719,0.9838706,0.00022307997,0.0014833488,0.012176616],"study_design_scores_gemma":[0.0005586217,0.00046126277,0.020230953,0.00016465381,0.00001283914,0.000010566127,0.0007858625,0.0066867443,0.958637,0.0008983827,0.011349071,0.00020403975],"about_ca_topic_score_codex":0.00008173306,"about_ca_topic_score_gemma":0.000060923114,"teacher_disagreement_score":0.025233597,"about_ca_system_score_codex":0.000031621654,"about_ca_system_score_gemma":0.00008176554,"threshold_uncertainty_score":0.34082952},"labels":[],"label_agreement":null},{"id":"W4393038518","doi":"10.1007/978-981-99-9338-3_2","title":"Navigating the Path from Lab to Market: Regulatory Challenges and Opportunities for Genome Editing Technologies for Agriculture","year":2024,"lang":"en","type":"book-chapter","venue":"Interdisciplinary biotechnological advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Campbell Scientific (Canada)","funders":"","keywords":"Path (computing); Genome editing; Agriculture; Genome; Business; Computational biology; Biotechnology; Computer science; Biology; Gene; Genetics; Computer network; Ecology","score_opus":0.020419536274637873,"score_gpt":0.2987922666261658,"score_spread":0.27837273035152793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393038518","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009896094,0.88047653,0.017944708,0.061381787,0.0014097844,0.0036420587,0.003019352,0.0011961018,0.021033559],"genre_scores_gemma":[0.5984494,0.20546249,0.04423926,0.0007758291,0.007520273,0.0041727256,0.0020642972,0.0006611046,0.13665465],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984196,0.0000055852365,0.00032725348,0.00081783975,0.00011571834,0.00031400216],"domain_scores_gemma":[0.9992381,0.000095301795,0.00012300658,0.00042089293,0.00007389848,0.00004882083],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016718141,0.00044861625,0.00036635494,0.000044697365,0.00021150288,0.00005069443,0.00048772036,0.00096094067,0.00000505769],"category_scores_gemma":[0.00006937727,0.00028378036,0.0001988947,0.000021197415,0.0003106393,0.0000070245906,0.0016053814,0.00053002645,0.0000016102344],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016060552,0.000023068778,6.78292e-7,0.0006469754,0.0003410208,0.000029935773,0.00030522523,0.00007522574,0.06994474,0.027598701,0.0028515414,0.8980223],"study_design_scores_gemma":[0.00016528033,0.0011151213,0.000013570046,0.0010469866,0.00009956464,0.000033871907,0.006955643,0.00007621661,0.021988712,0.1333532,0.8344908,0.0006610172],"about_ca_topic_score_codex":2.675539e-7,"about_ca_topic_score_gemma":0.000017673392,"teacher_disagreement_score":0.8973613,"about_ca_system_score_codex":0.000024739296,"about_ca_system_score_gemma":0.000010989003,"threshold_uncertainty_score":0.99996144},"labels":[],"label_agreement":null},{"id":"W4393116991","doi":"10.1111/bph.16337","title":"Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review","year":2024,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Nemzeti Kutatási Fejlesztési és Innovációs Hivatal; National Research, Development and Innovation Office; Semmelweis Egyetem; Hellenic Academic Libraries Link; U.S. Department of Veterans Affairs","keywords":"Medicine; Authorization; Drug; Pharmacology; Marketing authorization; Drug approval; Drug discovery; Bioinformatics; Biology","score_opus":0.011610309498520472,"score_gpt":0.3568857964543222,"score_spread":0.34527548695580174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393116991","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000097356584,0.99728656,0.00005346918,0.0012946944,0.00049781014,0.0005949744,0.000039489052,0.0000013717747,0.0001342583],"genre_scores_gemma":[0.000280077,0.99791324,0.000021313019,0.0008693773,0.00044913622,0.00007525276,0.000012238916,0.000028241177,0.00035114048],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984259,0.00034981928,0.000665463,0.00020484495,0.00011590784,0.0002380739],"domain_scores_gemma":[0.99945474,0.00012481255,0.00023062715,0.00011290938,0.000039851955,0.00003705774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018245248,0.0001983868,0.0007330448,0.00004548933,0.00004116809,0.000044320706,0.0005062582,0.00015461195,0.00002615356],"category_scores_gemma":[0.00010080931,0.00010960594,0.00029128575,0.00019727036,0.00017517815,0.0000026534049,0.0002025169,0.0009184314,0.0000034935113],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032487016,0.00006210335,5.105905e-7,0.007406636,0.00040426472,0.00010504466,0.00007143882,0.000009570872,0.0011410249,0.000018030443,0.27692938,0.7138195],"study_design_scores_gemma":[0.00094187615,0.00003112221,0.0000025707736,0.006477927,0.0007060256,0.00327746,0.000038169226,0.000011226573,0.000033499233,0.000010708939,0.98834366,0.00012574012],"about_ca_topic_score_codex":0.00005225273,"about_ca_topic_score_gemma":0.000055564364,"teacher_disagreement_score":0.7136938,"about_ca_system_score_codex":0.000021837763,"about_ca_system_score_gemma":0.00014465293,"threshold_uncertainty_score":0.44696006},"labels":[],"label_agreement":null},{"id":"W4393152183","doi":"10.1002/dvg.23589","title":"An oocyte‐specific Cas9‐expressing mouse for germline <scp>CRISPR</scp>/Cas9‐mediated genome editing","year":2024,"lang":"en","type":"article","venue":"genesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Cancer Institute; National Human Genome Research Institute; National Institutes of Health; University of British Columbia","keywords":"Cas9; Genome editing; Transgene; CRISPR; Biology; Genetics; Germline; Genetically modified mouse; Locus (genetics); Genome; Gene","score_opus":0.01142988674058267,"score_gpt":0.2918454769676439,"score_spread":0.28041559022706125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393152183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8426837,0.019729884,0.13582554,0.00004834705,0.0007926538,0.00031696825,0.00025287116,0.0001667061,0.0001833525],"genre_scores_gemma":[0.98529595,0.0008955541,0.0075991163,0.00011758086,0.0036490168,0.00011798855,0.00097645493,0.00015139744,0.0011969662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99820083,0.000034930585,0.000339788,0.0006928245,0.00016533253,0.00056631543],"domain_scores_gemma":[0.9990679,0.00007197679,0.00005070361,0.0005053554,0.00010352543,0.00020055813],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026731926,0.00030401847,0.00022988986,0.00012354502,0.00016085834,0.0001699853,0.0002663945,0.00023892638,0.00001883525],"category_scores_gemma":[0.000106862535,0.0003159293,0.00018067042,0.0001772638,0.00004630211,0.000012300058,0.000087705135,0.0001113349,0.00002806655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011703361,0.00003058056,0.00008294626,0.00012394224,0.00006904199,0.000016134376,0.00021894816,0.0029312903,0.9879914,0.00001032194,0.0044365022,0.0040771686],"study_design_scores_gemma":[0.000322526,0.00015043392,0.00058334647,0.000025141255,0.00004685109,0.000031298998,0.00032572064,0.0049378057,0.72244686,0.000012312036,0.27093107,0.00018662371],"about_ca_topic_score_codex":0.000015523961,"about_ca_topic_score_gemma":0.00001234871,"teacher_disagreement_score":0.26649457,"about_ca_system_score_codex":0.00003170768,"about_ca_system_score_gemma":0.00006359129,"threshold_uncertainty_score":0.99992925},"labels":[],"label_agreement":null},{"id":"W4393152568","doi":"10.62051/dpgwbz03","title":"Mitigating the Off-target Effects in CRISPR/Cas9-mediated Genetic Editing with Bioinformatic Technologies","year":2024,"lang":"en","type":"article","venue":"Transactions on Materials Biotechnology and Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Biology; Computer science; Genetics; Gene","score_opus":0.004733174749347196,"score_gpt":0.24946992341773014,"score_spread":0.24473674866838294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393152568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93253016,0.004393979,0.05912561,0.0030664913,0.00033741433,0.00027743034,0.000017567323,0.00020620105,0.000045126213],"genre_scores_gemma":[0.99461836,0.0011430349,0.004024909,0.00009616272,0.00003350202,0.0000616025,0.0000036699566,0.00000988103,0.00000888508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912363,0.00003121517,0.00019867565,0.00029186902,0.00009155598,0.00026307537],"domain_scores_gemma":[0.99970055,0.00006786102,0.000032353728,0.00016607107,0.000009666627,0.000023485489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002842671,0.00015195496,0.000135876,0.00022464583,0.00021954332,0.00007019175,0.00020126996,0.00023294201,0.000009616404],"category_scores_gemma":[0.00007421327,0.00009628225,0.000021343605,0.00041561914,0.00060131133,0.00001152802,0.000016194386,0.00016693467,0.000006462989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003802483,0.00003669101,0.00025055153,0.00036517507,0.000075219155,0.000019699874,0.00030783005,0.0042901756,0.9558361,0.0004209218,0.00008943971,0.03827014],"study_design_scores_gemma":[0.00018176548,0.00046541684,0.00045313852,0.00016563128,0.000017318049,0.00006355467,0.0012992661,0.0024690249,0.9930554,0.00019167601,0.0014679156,0.00016986001],"about_ca_topic_score_codex":0.000018409846,"about_ca_topic_score_gemma":0.000031682812,"teacher_disagreement_score":0.062088173,"about_ca_system_score_codex":0.000005824928,"about_ca_system_score_gemma":0.000045602505,"threshold_uncertainty_score":0.39262763},"labels":[],"label_agreement":null},{"id":"W4393162098","doi":"10.1002/ange.202404069","title":"A Sensitive Technique Unravels the Kinetics of Activation and <i>Trans</i> ‐Cleavage of CRISPR‐Cas Systems","year":2024,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Trans-activating crRNA; Kinetics; CRISPR; Chemistry; Ribonucleoprotein; Cleavage (geology); Activator (genetics); Ternary complex; RNA; Dissociation constant; Reaction rate constant; Biophysics; Stereochemistry; Enzyme; Biochemistry; Genome editing; Biology; Gene","score_opus":0.008347912256804828,"score_gpt":0.2714212092813662,"score_spread":0.2630732970245614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393162098","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07301581,0.0042575495,0.9199809,0.0001780684,0.0000989839,0.00035190114,0.0000724554,0.000020134845,0.0020242392],"genre_scores_gemma":[0.9990844,0.00036925176,0.00025381375,0.000021149877,0.00008747343,0.000016552132,0.000027332837,0.000016446642,0.00012358565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951065,0.000012331989,0.00015206232,0.0001527137,0.000077380624,0.00009483618],"domain_scores_gemma":[0.99969554,0.000026913654,0.00003269647,0.00016876501,0.000052364376,0.00002375063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010440505,0.00009670646,0.00011287004,0.000026612932,0.000013200367,0.000011464426,0.00005880743,0.00009471699,0.0000011709056],"category_scores_gemma":[0.000021526514,0.00007455805,0.000046248726,0.00008826299,0.000071508344,0.0000024281198,0.000034013883,0.000063971114,2.0486007e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012527242,0.000010026164,0.000026667696,0.00025403535,0.00004374651,0.0000014099721,0.0002324139,0.00005743847,0.9984292,0.000051701096,0.00063678704,0.00024405587],"study_design_scores_gemma":[0.000090704794,0.00007751597,0.00015455291,0.000117769705,0.000032011518,0.000023113816,0.00020150609,0.00003734933,0.99341846,0.000016139475,0.0057498356,0.00008104132],"about_ca_topic_score_codex":0.000019373767,"about_ca_topic_score_gemma":0.000002021275,"teacher_disagreement_score":0.9260686,"about_ca_system_score_codex":0.0000055757414,"about_ca_system_score_gemma":0.000013803441,"threshold_uncertainty_score":0.3040389},"labels":[],"label_agreement":null},{"id":"W4393162104","doi":"10.1002/anie.202404069","title":"A Sensitive Technique Unravels the Kinetics of Activation and <i>Trans</i> ‐Cleavage of CRISPR‐Cas Systems","year":2024,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Trans-activating crRNA; CRISPR; Kinetics; Ribonucleoprotein; Chemistry; Cleavage (geology); Activator (genetics); Ternary complex; RNA; Biophysics; Stereochemistry; Enzyme; Biochemistry; Biology; Genome editing; Gene; Physics","score_opus":0.0075866048177791745,"score_gpt":0.28112782428829314,"score_spread":0.27354121947051396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393162104","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008054284,0.000413415,0.9892718,0.0002998198,0.00032952658,0.0001500247,0.000118674245,0.000010368681,0.0013520796],"genre_scores_gemma":[0.99876344,0.00024597897,0.0002201734,0.000027001026,0.0004164082,0.000023205037,0.00019619522,0.0000110429355,0.00009657594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995136,0.000010314329,0.00015831913,0.00013201275,0.00012627311,0.000059433856],"domain_scores_gemma":[0.9997009,0.00003229812,0.00004532114,0.00008866632,0.00011633789,0.00001646081],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000970998,0.00007596369,0.00007156046,0.00004165189,0.000011498839,0.000015658525,0.00006297801,0.00007562946,0.0000036290953],"category_scores_gemma":[0.000036472124,0.00006277958,0.000041666095,0.0000561047,0.000057357483,0.000006786187,0.000027128022,0.000059218695,2.9160717e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018533074,0.000014373925,0.000020800506,0.000091049915,0.000054905508,9.653805e-7,0.00013473608,0.00012633686,0.99714667,0.00020464431,0.0019170097,0.00026997383],"study_design_scores_gemma":[0.00009906034,0.00005707497,0.0003082032,0.00014205063,0.00001909929,0.0000264327,0.00014271958,0.00020120201,0.9930325,0.00006395253,0.0058455,0.00006221162],"about_ca_topic_score_codex":0.00001854044,"about_ca_topic_score_gemma":0.000001977885,"teacher_disagreement_score":0.9907091,"about_ca_system_score_codex":0.000012145255,"about_ca_system_score_gemma":0.000011894868,"threshold_uncertainty_score":0.2560077},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"methods","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"agree"},{"id":"W4393170951","doi":"10.1007/978-1-0716-3798-2_4","title":"Combining a Base Deaminase Mutator with Phage-Assisted Evolution","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mutagenesis; Biology; Genetics; Gene; Genome; Bacteriophage; Function (biology); Mutation; Directed evolution; Computational biology; Mutant; Escherichia coli","score_opus":0.011433148240831333,"score_gpt":0.40229655459531977,"score_spread":0.3908634063544884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393170951","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15151745,0.005628906,0.84199286,0.00006430766,0.0002404732,0.00014903497,0.000007626957,0.0000383022,0.00036101346],"genre_scores_gemma":[0.56407356,0.000026039266,0.43552804,0.00008793452,0.000049605027,0.000049685666,0.000060029724,0.00003462966,0.000090491325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984862,0.00037477267,0.00022258279,0.0005270993,0.000058792903,0.00033053366],"domain_scores_gemma":[0.9994856,0.000050280792,0.000027600669,0.00032768075,0.00003459179,0.00007422522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061666174,0.00020660146,0.00019817389,0.0001660287,0.000032666994,0.00002385003,0.00014589034,0.00020944457,0.000013526273],"category_scores_gemma":[0.00014955715,0.00018423486,0.00008173088,0.0003052483,0.00009814384,0.0000024438052,0.000086956396,0.00018126446,0.00000480847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041843025,0.000031893625,0.00059805985,0.000047939167,0.000059212874,0.00012479516,0.000035065048,0.00047555869,0.97886527,0.0012206525,0.000030675295,0.018469015],"study_design_scores_gemma":[0.0006797738,0.00054169237,0.0010122797,0.00007774998,0.000045162702,0.00021900084,0.000079030266,0.0042572697,0.98479384,0.0007881152,0.0071391305,0.0003669317],"about_ca_topic_score_codex":0.000028050215,"about_ca_topic_score_gemma":0.000022633318,"teacher_disagreement_score":0.41255608,"about_ca_system_score_codex":0.000036828413,"about_ca_system_score_gemma":0.0000864213,"threshold_uncertainty_score":0.75128794},"labels":[],"label_agreement":null},{"id":"W4393200594","doi":"10.7554/elife.92819.2","title":"Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Endogeny; Induced pluripotent stem cell; HEK 293 cells; Computational biology; Cytokinesis; Biology; Protein engineering; Cell culture; Cell biology; Cell; Genetics; Cell division; Gene; Embryonic stem cell; Biochemistry; Enzyme","score_opus":0.05572595536639268,"score_gpt":0.3890586864800756,"score_spread":0.3333327311136829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393200594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9272409,0.06565443,0.0047619944,0.000115655595,0.0010933275,0.0006850925,0.00009428128,0.000051541097,0.00030278665],"genre_scores_gemma":[0.9932902,0.00070365344,0.004168929,0.00013540247,0.0011153201,0.00011024823,0.00018072706,0.00008598631,0.0002095724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985132,0.000022465794,0.00034552833,0.0006209381,0.00012812101,0.00036972712],"domain_scores_gemma":[0.9993613,0.00001969835,0.000073703995,0.00039031287,0.00009870772,0.000056273588],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029087975,0.0003110343,0.00033706252,0.0001271646,0.00007716623,0.000054496402,0.00021839664,0.00017284893,0.000002998634],"category_scores_gemma":[0.00008784071,0.00033756607,0.00019043226,0.000051146046,0.000045108747,0.0000012288546,0.00108571,0.00030051632,0.000004564156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025490235,0.000040239498,0.0012134395,0.0016617245,0.00046222247,0.00007879118,0.0017144476,0.03448467,0.95570725,0.00009631373,0.0014020557,0.003113345],"study_design_scores_gemma":[0.0014717405,0.00021122396,0.0005383798,0.0024256804,0.00057296397,0.00015036605,0.0032876553,0.027797516,0.93129635,0.0025414869,0.027276998,0.0024296618],"about_ca_topic_score_codex":0.00008855796,"about_ca_topic_score_gemma":0.00008435556,"teacher_disagreement_score":0.06604926,"about_ca_system_score_codex":0.000074641095,"about_ca_system_score_gemma":0.00009732064,"threshold_uncertainty_score":0.9999076},"labels":[],"label_agreement":null},{"id":"W4393374568","doi":"10.1093/hmg/ddae045","title":"Base editing correction of <i>OCRL</i> in Lowe syndrome: ABE-mediated functional rescue in patient-derived fibroblasts","year":2024,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; National Institutes of Health; Research to Prevent Blindness; Children's Health Research Institute; International Retinal Research Foundation","keywords":"Point mutation; Biology; Mutation; Genetic disorder; Gene; Genetic enhancement; Molecular biology; Genetics","score_opus":0.0061620189452451825,"score_gpt":0.24816062895037727,"score_spread":0.2419986100051321,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393374568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898122,0.0023751264,0.0067745163,0.00001832754,0.0005465955,0.0002098523,0.000018900468,0.000022366878,0.00022212724],"genre_scores_gemma":[0.99896747,0.0000829597,0.0004302724,0.000048720038,0.000088041976,0.000027650642,0.0002613481,0.000048638874,0.000044891647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986063,0.000058968635,0.00041952732,0.00042277176,0.00020224878,0.00029014074],"domain_scores_gemma":[0.9995424,0.000016893937,0.00004258122,0.00027512107,0.000054433473,0.00006854859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001342385,0.00020083571,0.00017783366,0.0002256893,0.000027596014,0.000024328023,0.00010580857,0.00017892983,0.000032752414],"category_scores_gemma":[0.00006436286,0.00023600672,0.00009443819,0.0002972453,0.000052482024,0.000004230199,0.000098191544,0.00019257302,0.0000070611522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018624261,0.000053251217,0.0005838349,0.00008347653,0.000024600498,0.00016987609,0.00009472838,0.05169865,0.94581753,0.000009661565,0.00035194078,0.0010937947],"study_design_scores_gemma":[0.0006495075,0.00047766606,0.015480827,0.0003172065,0.000018855942,0.00011185184,0.00013044599,0.011202172,0.97004396,0.000046399706,0.0011805578,0.00034056167],"about_ca_topic_score_codex":0.000028247523,"about_ca_topic_score_gemma":0.00015606786,"teacher_disagreement_score":0.04049648,"about_ca_system_score_codex":0.000033425797,"about_ca_system_score_gemma":0.00006325579,"threshold_uncertainty_score":0.96240747},"labels":[],"label_agreement":null},{"id":"W4393503396","doi":"10.5281/zenodo.10214517","title":"A mobile CRISPRi collection enables genetic interaction studies for the essential genes of Escherichia coli","year":2023,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Escherichia coli; Gene; Mobile genetic elements; Genetics; Biology; Computational biology; Genome","score_opus":0.026816562700319076,"score_gpt":0.3212765046213879,"score_spread":0.29445994192106884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393503396","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014216919,0.012051606,0.024389526,0.00017570145,0.0023075573,0.0035546452,0.9427321,0.0003066702,0.0002652736],"genre_scores_gemma":[0.008544645,0.022041626,0.00032294056,0.000045374825,0.0010118777,0.000004574613,0.9659342,0.0011476092,0.00094716356],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988321,0.00011485245,0.00027993438,0.00036343478,0.00018054561,0.00022914115],"domain_scores_gemma":[0.9987746,0.000035869816,0.00015314337,0.00045147483,0.0005366075,0.00004832691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026911686,0.00017740115,0.00018756781,0.00012741139,0.0008278851,0.00014290477,0.00055576867,0.00013223462,0.00017968638],"category_scores_gemma":[0.00047455067,0.00016073255,0.00010274611,0.0002722183,0.00011900373,0.000005445525,0.0007217591,0.0001455773,0.00023031833],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093034374,0.000045857407,1.07639835e-7,0.00029803056,0.00026569123,0.0000010271078,0.00010346862,0.002334367,0.056494612,0.0000024596993,0.9364412,0.0039201365],"study_design_scores_gemma":[0.00028129824,0.0005224302,0.0000220632,0.000037260445,0.000103464736,0.000015689391,0.00059867365,0.0003325319,0.019327372,0.000007345564,0.9785951,0.00015677839],"about_ca_topic_score_codex":0.000048257505,"about_ca_topic_score_gemma":0.000008475882,"teacher_disagreement_score":0.042153884,"about_ca_system_score_codex":0.000043425985,"about_ca_system_score_gemma":0.0000091673255,"threshold_uncertainty_score":0.6554484},"labels":[],"label_agreement":null},{"id":"W4393645725","doi":"10.5281/zenodo.4721071","title":"Datasets for Eirew et al Accurate determination of CRISPR-mediated gene fitness in transplantable tumours","year":2021,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Computational biology; Biology; Gene; Genetics","score_opus":0.02134980922006902,"score_gpt":0.308593319571865,"score_spread":0.28724351035179596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393645725","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013016216,0.00033229752,0.016170999,0.00016527636,0.000105105915,0.00040881624,0.981407,0.000028181254,0.000080687096],"genre_scores_gemma":[0.005122694,0.0014056572,0.00025834134,0.00017204067,0.000055008037,3.3907844e-7,0.99255735,0.00039695285,0.00003161038],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986164,0.00015982207,0.00031202513,0.0004479873,0.00018746514,0.00027630906],"domain_scores_gemma":[0.99906266,0.000021104492,0.000117829964,0.0004801655,0.0002359679,0.00008227286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045633662,0.0001852624,0.00021697146,0.00016310596,0.00019248741,0.00012474346,0.0006095633,0.00014723885,0.0004670105],"category_scores_gemma":[0.00040459452,0.00021448909,0.000061063714,0.00021449623,0.0000523026,0.000011975139,0.00039480146,0.00018621972,0.000056882374],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008227746,0.00008776928,5.898916e-7,0.00025659942,0.000023266513,0.000012887006,0.000028683904,0.00017630243,0.063504964,0.0000016987433,0.9337107,0.002114287],"study_design_scores_gemma":[0.000663573,0.00017416685,0.00007297526,0.00007395117,0.000027650858,0.000054410943,0.000039529838,0.00024267424,0.038011737,0.000002219394,0.96042806,0.00020902907],"about_ca_topic_score_codex":0.00003718818,"about_ca_topic_score_gemma":0.00002285707,"teacher_disagreement_score":0.02671741,"about_ca_system_score_codex":0.000029357334,"about_ca_system_score_gemma":0.000015916205,"threshold_uncertainty_score":0.87466115},"labels":[],"label_agreement":null},{"id":"W4393795544","doi":"10.5281/zenodo.10214516","title":"A mobile CRISPRi collection enables genetic interaction studies for the essential genes of Escherichia coli","year":2023,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Escherichia coli; Mobile genetic elements; Gene; Biology; Genetics; Computational biology; Genome","score_opus":0.026816562700319076,"score_gpt":0.3212765046213879,"score_spread":0.29445994192106884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393795544","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014216919,0.012051606,0.024389526,0.00017570145,0.0023075573,0.0035546452,0.9427321,0.0003066702,0.0002652736],"genre_scores_gemma":[0.008544645,0.022041626,0.00032294056,0.000045374825,0.0010118777,0.000004574613,0.9659342,0.0011476092,0.00094716356],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988321,0.00011485245,0.00027993438,0.00036343478,0.00018054561,0.00022914115],"domain_scores_gemma":[0.9987746,0.000035869816,0.00015314337,0.00045147483,0.0005366075,0.00004832691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026911686,0.00017740115,0.00018756781,0.00012741139,0.0008278851,0.00014290477,0.00055576867,0.00013223462,0.00017968638],"category_scores_gemma":[0.00047455067,0.00016073255,0.00010274611,0.0002722183,0.00011900373,0.000005445525,0.0007217591,0.0001455773,0.00023031833],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093034374,0.000045857407,1.07639835e-7,0.00029803056,0.00026569123,0.0000010271078,0.00010346862,0.002334367,0.056494612,0.0000024596993,0.9364412,0.0039201365],"study_design_scores_gemma":[0.00028129824,0.0005224302,0.0000220632,0.000037260445,0.000103464736,0.000015689391,0.00059867365,0.0003325319,0.019327372,0.000007345564,0.9785951,0.00015677839],"about_ca_topic_score_codex":0.000048257505,"about_ca_topic_score_gemma":0.000008475882,"teacher_disagreement_score":0.042153884,"about_ca_system_score_codex":0.000043425985,"about_ca_system_score_gemma":0.0000091673255,"threshold_uncertainty_score":0.6554484},"labels":[],"label_agreement":null},{"id":"W4394063266","doi":"10.1101/2024.04.06.588385","title":"Nuclear release of eIF1 globally increases stringency of start-codon selection to preserve mitotic arrest physiology","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Mitosis; Selection (genetic algorithm); Biology; Cell biology; Computer science","score_opus":0.006909975439108112,"score_gpt":0.23876393196186813,"score_spread":0.23185395652276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394063266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99533576,0.0024676272,0.0006050193,0.000040170467,0.00066326436,0.0005160473,0.00028486707,0.000075539465,0.000011690232],"genre_scores_gemma":[0.99645674,0.00035868326,0.0025243023,0.000034878616,0.00046324817,0.000045577875,0.0000022408362,0.00010844616,0.000005865111],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978885,0.00008751684,0.00055549404,0.0008381121,0.000248691,0.00038170273],"domain_scores_gemma":[0.99823624,0.000018373446,0.00023263742,0.0008995744,0.00040084808,0.00021232659],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023321497,0.00041718196,0.0004933019,0.00018854796,0.000040161423,0.00003433687,0.00050289335,0.0004733796,0.000023030261],"category_scores_gemma":[0.00029959888,0.00046994435,0.00021322927,0.00033974837,0.00007509872,0.000004420997,0.0009508501,0.00030282963,0.000011738442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013656054,0.00014519994,0.001347765,0.0011141724,0.00025962346,0.0000049943665,0.0000061233027,0.0046815053,0.99149394,0.00011768573,0.00068904646,0.0000034122559],"study_design_scores_gemma":[0.00024277618,0.0003604908,0.03871592,0.0004151526,0.00016602922,3.471262e-8,0.0000040413147,0.0004727473,0.9569623,0.000004712519,0.0021977313,0.00045804738],"about_ca_topic_score_codex":0.00024300264,"about_ca_topic_score_gemma":0.000029272036,"teacher_disagreement_score":0.037368156,"about_ca_system_score_codex":0.000060659302,"about_ca_system_score_gemma":0.0003527955,"threshold_uncertainty_score":0.99977523},"labels":[],"label_agreement":null},{"id":"W4394071394","doi":"10.6084/m9.figshare.13272894.v2","title":"GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Western University","funders":"","keywords":"Autophagy; Phosphatidylinositol; BECN1; Regulator; Cell biology; Kinase; Chemistry; Biology; Biochemistry; Gene","score_opus":0.016051535628714145,"score_gpt":0.2956068468907967,"score_spread":0.27955531126208255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394071394","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029647324,0.0082917735,0.0000039520473,0.0000478679,0.00006751324,0.0002917385,0.99094605,0.000006412324,0.000048214803],"genre_scores_gemma":[0.0049467064,0.000104012055,0.00010969595,0.0003368208,0.00026350093,0.00010676568,0.9939837,0.000024606226,0.00012421102],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99886435,0.000056939203,0.00028459614,0.00041003636,0.00016234373,0.00022172915],"domain_scores_gemma":[0.9988743,0.00008490938,0.00019020561,0.0006254324,0.00014695237,0.000078174846],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000595105,0.0002847227,0.00038747548,0.000033202174,0.00007774637,0.000043045726,0.00030187244,0.0002876068,0.0094220955],"category_scores_gemma":[0.0005538471,0.00023326633,0.00015844326,0.000089067435,0.00004608367,0.0000022907543,0.00041525246,0.00018894381,0.000020503081],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006098977,0.000015188927,0.0000010427217,0.0003571358,0.00013517324,0.000011963858,0.000060932514,0.000028162765,0.0015228293,0.0000012641163,0.9972885,0.00051680184],"study_design_scores_gemma":[0.0010002955,0.00009018503,0.000202307,0.000621403,0.00006309769,0.000019684934,0.00006217169,0.0001324627,0.087234885,0.0000059015338,0.9103107,0.00025690324],"about_ca_topic_score_codex":0.00003860936,"about_ca_topic_score_gemma":0.000047233993,"teacher_disagreement_score":0.08697781,"about_ca_system_score_codex":0.000009833517,"about_ca_system_score_gemma":0.00011869493,"threshold_uncertainty_score":0.99148345},"labels":[],"label_agreement":null},{"id":"W4394082753","doi":"10.6084/m9.figshare.20418213","title":"Additional file 3 of Target residence of Cas9-sgRNA influences DNA double-strand break repair pathway choices in CRISPR/Cas9 genome editing","year":2022,"lang":"en","type":"dataset","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"CRISPR; Genome editing; Subgenomic mRNA; Cas9; Genetics; Biology; DNA; Computational biology; Gene","score_opus":0.01595037167352723,"score_gpt":0.3055467474937591,"score_spread":0.28959637582023184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394082753","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0041510444,0.00060521526,0.0000021490425,0.000006576365,0.00010465159,0.00031616725,0.99432385,0.0000010003487,0.00048934645],"genre_scores_gemma":[0.0005408225,0.00009458485,0.0018400985,0.000014153044,0.00024475838,0.0002060333,0.99658155,0.000017656357,0.0004603394],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982246,0.000059177804,0.0006007061,0.0005596862,0.00029362921,0.00026217097],"domain_scores_gemma":[0.99877584,0.0001618648,0.00038884053,0.00051925494,0.00008307961,0.000071138915],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027245228,0.00025916233,0.00041436686,0.00012423554,0.00006220555,0.00003250058,0.00078969286,0.00024061372,0.61882395],"category_scores_gemma":[0.00027921077,0.00027804342,0.00013859554,0.00017141982,0.00010079479,0.000013061521,0.0005417549,0.0002544779,0.000011651739],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009017634,0.0000620123,0.000014630893,0.00012277975,0.000061281724,0.00003172675,0.000034755467,0.0009448779,0.006621995,7.572592e-8,0.9917533,0.00026237915],"study_design_scores_gemma":[0.0004064653,0.0001809037,0.0005160799,0.00021525832,0.000022319373,0.00002369223,0.00014818546,0.000008164936,0.018996978,0.0000020766379,0.9792092,0.00027071306],"about_ca_topic_score_codex":0.0004270002,"about_ca_topic_score_gemma":0.0010625557,"teacher_disagreement_score":0.6188123,"about_ca_system_score_codex":0.000019521021,"about_ca_system_score_gemma":0.00034296323,"threshold_uncertainty_score":0.99996716},"labels":[],"label_agreement":null},{"id":"W4394140573","doi":"10.6084/m9.figshare.13272894","title":"GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Western University","funders":"","keywords":"Phosphatidylinositol; Autophagy; BECN1; Regulator; Negative regulator; Kinase; Chemistry; Cell biology; Biology; Biochemistry; Signal transduction; Gene","score_opus":0.016051535628714145,"score_gpt":0.2956068468907967,"score_spread":0.27955531126208255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394140573","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029647324,0.0082917735,0.0000039520473,0.0000478679,0.00006751324,0.0002917385,0.99094605,0.000006412324,0.000048214803],"genre_scores_gemma":[0.0049467064,0.000104012055,0.00010969595,0.0003368208,0.00026350093,0.00010676568,0.9939837,0.000024606226,0.00012421102],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99886435,0.000056939203,0.00028459614,0.00041003636,0.00016234373,0.00022172915],"domain_scores_gemma":[0.9988743,0.00008490938,0.00019020561,0.0006254324,0.00014695237,0.000078174846],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000595105,0.0002847227,0.00038747548,0.000033202174,0.00007774637,0.000043045726,0.00030187244,0.0002876068,0.0094220955],"category_scores_gemma":[0.0005538471,0.00023326633,0.00015844326,0.000089067435,0.00004608367,0.0000022907543,0.00041525246,0.00018894381,0.000020503081],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006098977,0.000015188927,0.0000010427217,0.0003571358,0.00013517324,0.000011963858,0.000060932514,0.000028162765,0.0015228293,0.0000012641163,0.9972885,0.00051680184],"study_design_scores_gemma":[0.0010002955,0.00009018503,0.000202307,0.000621403,0.00006309769,0.000019684934,0.00006217169,0.0001324627,0.087234885,0.0000059015338,0.9103107,0.00025690324],"about_ca_topic_score_codex":0.00003860936,"about_ca_topic_score_gemma":0.000047233993,"teacher_disagreement_score":0.08697781,"about_ca_system_score_codex":0.000009833517,"about_ca_system_score_gemma":0.00011869493,"threshold_uncertainty_score":0.99148345},"labels":[],"label_agreement":null},{"id":"W4394171187","doi":"10.6084/m9.figshare.20375863","title":"Additional file 3 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; X-inactivation; Genetics; Biology; Chromosome; X chromosome; Gene","score_opus":0.008913032850297686,"score_gpt":0.25116643877061984,"score_spread":0.24225340592032216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394171187","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000068048874,0.0006147858,0.0000032514306,0.000010270956,0.000031392305,0.00021463717,0.99904746,0.0000033243962,0.000006814935],"genre_scores_gemma":[0.00015095698,0.000048103047,0.00015423197,0.000049048445,0.00017476347,0.0007594207,0.99861616,0.000015169413,0.000032134503],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99921674,0.000026933987,0.00018925613,0.0002831181,0.00015841298,0.0001255715],"domain_scores_gemma":[0.9992353,0.0001493208,0.00017049837,0.0002785541,0.00010844681,0.000057891495],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000121633275,0.00015909265,0.00020638044,0.000076534474,0.000029720806,0.0000063680563,0.00015675882,0.00017744579,0.98260903],"category_scores_gemma":[0.0011348503,0.00018588231,0.00004923378,0.000087456974,0.000008151017,0.0000011907432,0.00024114568,0.00008784337,0.000030290545],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001359817,0.000020478863,2.5903825e-7,0.00011000842,0.000040560542,0.0000013187085,0.000003512964,0.000067482615,0.006577724,1.7720119e-8,0.9926105,0.0005545164],"study_design_scores_gemma":[0.00010923444,0.00024969017,0.0010707623,0.00045359644,0.000017315338,0.0000030175431,0.000008013121,0.000008082659,0.016257932,0.0000023030047,0.9816491,0.00017097557],"about_ca_topic_score_codex":0.000024777646,"about_ca_topic_score_gemma":0.00008989515,"teacher_disagreement_score":0.98257875,"about_ca_system_score_codex":0.000014983632,"about_ca_system_score_gemma":0.000065960776,"threshold_uncertainty_score":0.75800604},"labels":[],"label_agreement":null},{"id":"W4394184698","doi":"10.6084/m9.figshare.19663872","title":"Additional file 2 of Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data","year":2022,"lang":"en","type":"dataset","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Enhancer; Gene; Set (abstract data type); Interpretation (philosophy); Computational biology; Genome; Genetics; Biology; Computer science; Gene expression; Programming language","score_opus":0.031023110497174235,"score_gpt":0.3197890896540921,"score_spread":0.2887659791569179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394184698","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005204278,0.00033552956,0.00058378547,0.0000026263904,0.0001607394,0.00036528282,0.99795884,4.3798505e-7,0.00007234102],"genre_scores_gemma":[0.00017923098,0.00008224392,0.010956528,0.00002807772,0.00011217329,0.00013676549,0.9878514,0.000024159131,0.00062946684],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984041,0.000060802216,0.00045462925,0.0006241834,0.00027516636,0.00018110707],"domain_scores_gemma":[0.9980072,0.00011155516,0.00043194214,0.001276134,0.00011021998,0.00006299364],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010501461,0.00024572172,0.00036328819,0.00006725592,0.000045330584,0.000019477282,0.0012603414,0.00019111815,0.6917666],"category_scores_gemma":[0.00014583809,0.00028118936,0.00008148735,0.000065816486,0.00007091106,0.000009095414,0.0019588692,0.00015564184,0.000024060932],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069920185,0.00005697746,3.471719e-7,0.000052255087,0.0002386886,0.0000032973564,0.0000115226985,0.00054592587,0.088102065,6.4722645e-9,0.9090723,0.0018467316],"study_design_scores_gemma":[0.00023799704,0.00017929116,0.00012881758,0.000042686454,0.000055567773,0.000005758628,0.000052822947,0.00011341474,0.10334439,0.0000011189691,0.8955986,0.00023952588],"about_ca_topic_score_codex":0.000025446961,"about_ca_topic_score_gemma":0.000023951288,"teacher_disagreement_score":0.69174254,"about_ca_system_score_codex":0.000031713684,"about_ca_system_score_gemma":0.00030885157,"threshold_uncertainty_score":0.999964},"labels":[],"label_agreement":null},{"id":"W4394199787","doi":"10.6084/m9.figshare.21069666","title":"Additional file 4 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Mutation; Genetics; Germline; Germline mutation; Transcriptome; Immune dysregulation; Biology; Immune system; Computational biology; Cancer research; Gene; Gene expression","score_opus":0.0064836906366235,"score_gpt":0.2160776578671163,"score_spread":0.2095939672304928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394199787","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004649806,0.00008501721,0.000005529048,0.000002139551,0.000016874968,0.00017518799,0.9950529,0.0000035698592,0.000008976276],"genre_scores_gemma":[0.0037895192,0.000011187022,0.000030792384,0.000004925646,0.00004318502,0.0004537691,0.99554884,0.000014794361,0.00010296537],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992954,0.00002754908,0.00023729313,0.00020657467,0.00013196765,0.00010119209],"domain_scores_gemma":[0.9995107,0.000035614525,0.00022450041,0.00014598825,0.00006050806,0.000022708338],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002304891,0.00012421765,0.00014661884,0.00010807344,0.000029050894,0.000005222505,0.000057753477,0.00013754351,0.80574507],"category_scores_gemma":[0.00011099629,0.0001380481,0.000026100808,0.00012049951,0.000009120984,0.000006221143,0.000045178003,0.00007481137,0.0000027642545],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014709555,0.00005513764,2.5619767e-7,0.00040540486,0.000012471723,0.000001306464,0.00002957514,0.00039460178,0.11780559,9.339895e-9,0.88084155,0.00030700307],"study_design_scores_gemma":[0.00037944352,0.0005544619,0.008470849,0.0006059013,0.0000103689745,0.000016887352,0.00002761727,0.00012330935,0.01679727,5.156001e-7,0.97283703,0.00017635204],"about_ca_topic_score_codex":0.000003985517,"about_ca_topic_score_gemma":0.00002970312,"teacher_disagreement_score":0.8057423,"about_ca_system_score_codex":0.000052896583,"about_ca_system_score_gemma":0.00003688243,"threshold_uncertainty_score":0.56294376},"labels":[],"label_agreement":null},{"id":"W4394264527","doi":"10.6084/m9.figshare.20375875","title":"Additional file 7 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; X-inactivation; Genetics; Chromosome; Biology; X chromosome; Computer science; Gene","score_opus":0.00893412398097382,"score_gpt":0.25138133690811504,"score_spread":0.24244721292714122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394264527","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000068036876,0.0006166158,0.0000032651767,0.0000103079365,0.000031137068,0.00021473633,0.9990458,0.000003328797,0.000006787505],"genre_scores_gemma":[0.000152626,0.000048192607,0.00015437258,0.000049135597,0.00017320081,0.0007589134,0.99861705,0.000015172433,0.00003132572],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992165,0.000026945916,0.00018931663,0.0002832061,0.00015841449,0.0001256032],"domain_scores_gemma":[0.9992362,0.00014931963,0.00017051309,0.00027865756,0.00010739116,0.00005790537],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000121779185,0.00015912826,0.00020646106,0.00007656968,0.000029736508,0.000006371664,0.00015682731,0.00017746359,0.9821032],"category_scores_gemma":[0.0011133663,0.00018593535,0.000049240993,0.00008747347,0.000008153549,0.0000011910413,0.00024126007,0.00008785754,0.00002958578],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013540075,0.000020507241,2.5873905e-7,0.00011021574,0.000040599705,0.0000013241289,0.0000035218154,0.00006753025,0.006549925,1.8300424e-8,0.9926343,0.0005582376],"study_design_scores_gemma":[0.0001087741,0.00025088424,0.0010714063,0.00045904092,0.000017442972,0.0000030464155,0.000008034566,0.000008105624,0.01612729,0.000002323751,0.9817726,0.00017105904],"about_ca_topic_score_codex":0.000024794825,"about_ca_topic_score_gemma":0.00009057851,"teacher_disagreement_score":0.9820736,"about_ca_system_score_codex":0.0000149353755,"about_ca_system_score_gemma":0.00006581904,"threshold_uncertainty_score":0.75822234},"labels":[],"label_agreement":null},{"id":"W4394265409","doi":"10.6084/m9.figshare.21069672","title":"Additional file 6 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Germline; Transcriptome; Mutation; Germline mutation; Genetics; Biology; Computational biology; Gene; Gene expression","score_opus":0.006436337047733269,"score_gpt":0.21583716698797464,"score_spread":0.20940082994024137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394265409","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0046421066,0.000085155385,0.000005525437,0.0000021510834,0.000016876967,0.00017536436,0.9950602,0.0000035697258,0.000009061894],"genre_scores_gemma":[0.0037598491,0.000011172034,0.000030782136,0.0000049281916,0.00004319056,0.0004542009,0.99557686,0.000014796285,0.000104200095],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99929535,0.00002757026,0.00023729107,0.00020660077,0.00013197491,0.000101198864],"domain_scores_gemma":[0.9995103,0.000035580237,0.00022449587,0.00014596718,0.000060945513,0.00002271138],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000023059692,0.00012422955,0.00014663929,0.0001080678,0.000029047715,0.0000052227033,0.000057739,0.0001375433,0.80457443],"category_scores_gemma":[0.00011138784,0.00013805571,0.000026102181,0.000120539065,0.0000091215,0.0000062216054,0.000045181765,0.00007482393,0.000002753354],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014566192,0.000055341006,2.547597e-7,0.00040533347,0.000012466797,0.0000013053392,0.000029624156,0.00039380539,0.11828426,9.410235e-9,0.88036484,0.00030708138],"study_design_scores_gemma":[0.0003788101,0.00054716226,0.008526301,0.0006050205,0.000010355505,0.000016850083,0.00002762205,0.00012171243,0.016778756,5.1472904e-7,0.9728108,0.00017610512],"about_ca_topic_score_codex":0.0000040528603,"about_ca_topic_score_gemma":0.000030244604,"teacher_disagreement_score":0.8045717,"about_ca_system_score_codex":0.000052847794,"about_ca_system_score_gemma":0.000036923753,"threshold_uncertainty_score":0.5629748},"labels":[],"label_agreement":null},{"id":"W4394312124","doi":"10.6084/m9.figshare.20375860","title":"Additional file 2 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; X-inactivation; Genetics; Biology; Chromosome; X chromosome; Gene","score_opus":0.008752272366880162,"score_gpt":0.25100384885334204,"score_spread":0.24225157648646187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394312124","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006715415,0.000620707,0.0000031696873,0.000010264876,0.0000312766,0.00021424536,0.9990429,0.0000033269275,0.0000069183116],"genre_scores_gemma":[0.00014723084,0.000048636633,0.00015281494,0.000049099086,0.00017531613,0.0007593574,0.99862075,0.000015154792,0.00003166458],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99921685,0.000026949694,0.00018925598,0.00028303737,0.00015834652,0.00012553786],"domain_scores_gemma":[0.999237,0.00014859873,0.0001706933,0.00027844994,0.00010734516,0.000057888334],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000012107244,0.00015906687,0.00020640738,0.00007651206,0.000029725188,0.0000063686275,0.0001567701,0.00017746075,0.98270506],"category_scores_gemma":[0.0011225208,0.00018587036,0.00004922793,0.000087424494,0.000008150374,0.0000011906434,0.0002412765,0.00008784142,0.00002969112],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013460279,0.000020490013,2.512458e-7,0.000109239765,0.000040608484,0.0000013374744,0.000003516937,0.00006778848,0.0063568447,1.8119723e-8,0.9928251,0.00056132517],"study_design_scores_gemma":[0.00010875369,0.0002505764,0.0010630467,0.00045026536,0.000017439394,0.0000030565561,0.000007989581,0.000008037754,0.015884662,0.0000023184386,0.9820329,0.0001709842],"about_ca_topic_score_codex":0.000024746603,"about_ca_topic_score_gemma":0.00008981802,"teacher_disagreement_score":0.9826754,"about_ca_system_score_codex":0.000014932533,"about_ca_system_score_gemma":0.00006565661,"threshold_uncertainty_score":0.75795734},"labels":[],"label_agreement":null},{"id":"W4394422576","doi":"10.6084/m9.figshare.20375869","title":"Additional file 5 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; Genetics; X-inactivation; Biology; Chromosome; X chromosome; Gene","score_opus":0.008918984947860087,"score_gpt":0.2513230868127082,"score_spread":0.24240410186484812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394422576","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000680566,0.00061616296,0.00000326103,0.00001030444,0.000031131793,0.00021475914,0.9990462,0.0000033287015,0.0000067872447],"genre_scores_gemma":[0.0001531437,0.000048109112,0.00015440771,0.00004913579,0.0001731832,0.0007595689,0.998616,0.000015170694,0.00003132072],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99921656,0.000026951846,0.00018931362,0.00028317832,0.00015841248,0.0001255819],"domain_scores_gemma":[0.99923617,0.00014941268,0.00017051864,0.00027864566,0.00010737587,0.000057900044],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000012178134,0.00015911763,0.00020645883,0.000076564764,0.000029735858,0.0000063685916,0.00015681126,0.00017746777,0.98233396],"category_scores_gemma":[0.0011242751,0.00018591841,0.00004924352,0.00008747285,0.000008152418,0.0000011909036,0.00024124268,0.00008785046,0.000029528044],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013542715,0.000020507641,2.5896665e-7,0.00010932852,0.000040596515,0.0000013240644,0.0000035175524,0.00006743337,0.0065349666,1.8345558e-8,0.99265313,0.0005553982],"study_design_scores_gemma":[0.00010878978,0.00025054527,0.0010922367,0.0004549915,0.000017445542,0.0000030475162,0.0000080409645,0.000008056796,0.016067607,0.00000231367,0.9818159,0.00017106129],"about_ca_topic_score_codex":0.000024780566,"about_ca_topic_score_gemma":0.000090540525,"teacher_disagreement_score":0.98230445,"about_ca_system_score_codex":0.000014932971,"about_ca_system_score_gemma":0.000065799344,"threshold_uncertainty_score":0.75815326},"labels":[],"label_agreement":null},{"id":"W4394433960","doi":"10.6084/m9.figshare.21069669","title":"Additional file 5 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Transcriptome; Germline; Germline mutation; Mutation; Genetics; Biology; Immune system; Computational biology; Gene; Gene expression","score_opus":0.006439455628283173,"score_gpt":0.21587763223623707,"score_spread":0.20943817660795389,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394433960","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0046689394,0.00008492381,0.0000055139094,0.0000021494136,0.000016875047,0.00017514724,0.9950339,0.0000035699268,0.000008962367],"genre_scores_gemma":[0.0037574628,0.000011186359,0.00003079079,0.0000049282926,0.00004318915,0.00045374152,0.99558026,0.000014796083,0.00010363147],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99929535,0.000027569215,0.00023728653,0.00020659757,0.00013197443,0.00010118989],"domain_scores_gemma":[0.99951035,0.000035575424,0.00022449197,0.00014596577,0.000060934104,0.000022710394],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000023058978,0.00012422832,0.00014664068,0.00010806967,0.000029052055,0.000005220504,0.000057734633,0.0001375493,0.8057083],"category_scores_gemma":[0.00011138352,0.00013805032,0.000026103866,0.00012053324,0.000009121022,0.0000062211343,0.00004517999,0.000074819,0.0000027481217],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014495995,0.000055083947,2.5516516e-7,0.00040508222,0.000012458826,0.0000013050519,0.000029530682,0.00039842972,0.11835158,9.334506e-9,0.8802942,0.00030709823],"study_design_scores_gemma":[0.0003799339,0.00054904184,0.008606888,0.0006073817,0.0000103910015,0.00001691938,0.000027679378,0.00012277528,0.016939335,5.1415304e-7,0.97256243,0.00017669208],"about_ca_topic_score_codex":0.000004016908,"about_ca_topic_score_gemma":0.00002979569,"teacher_disagreement_score":0.80570555,"about_ca_system_score_codex":0.00005290662,"about_ca_system_score_gemma":0.000036918398,"threshold_uncertainty_score":0.5629529},"labels":[],"label_agreement":null},{"id":"W4394448787","doi":"10.6084/m9.figshare.20375866","title":"Additional file 4 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; Genetics; X-inactivation; Biology; Chromosome; X chromosome; Gene","score_opus":0.00898681131451526,"score_gpt":0.2515722404250875,"score_spread":0.24258542911057226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394448787","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000677544,0.00061687746,0.0000032705764,0.0000102534705,0.000031130992,0.00021480834,0.9990458,0.000003328565,0.0000067984147],"genre_scores_gemma":[0.00015455717,0.000048113747,0.00015442133,0.00004910906,0.00017317108,0.0007596432,0.9986147,0.000015169293,0.000031105617],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992166,0.000026930713,0.00018931928,0.0002831446,0.00015840375,0.00012558482],"domain_scores_gemma":[0.9992367,0.00014958906,0.00017052561,0.00027869188,0.000106570085,0.00005789445],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000012172424,0.00015910297,0.00020642582,0.00007656764,0.000029734581,0.0000063712123,0.00015686623,0.00017745976,0.9823383],"category_scores_gemma":[0.0011200833,0.0001859152,0.00004923733,0.00008744657,0.00000815238,0.0000011909053,0.0002412313,0.00008784083,0.000029714201],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000137414545,0.000020505791,2.597966e-7,0.00010929775,0.000040595485,0.0000013240973,0.000003519238,0.000066661945,0.0064898557,1.8336083e-8,0.9926996,0.0005545831],"study_design_scores_gemma":[0.0001088661,0.00025373153,0.0010758691,0.0004547493,0.000017442217,0.0000030476785,0.000008038359,0.000008111353,0.01595666,0.0000023255125,0.9819401,0.00017106463],"about_ca_topic_score_codex":0.000024572708,"about_ca_topic_score_gemma":0.00009023855,"teacher_disagreement_score":0.9823086,"about_ca_system_score_codex":0.0000149299285,"about_ca_system_score_gemma":0.00006573052,"threshold_uncertainty_score":0.75814015},"labels":[],"label_agreement":null},{"id":"W4394465416","doi":"10.6084/m9.figshare.21069663","title":"Additional file 3 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Germline; Transcriptome; Mutation; Germline mutation; Genetics; Biology; Computational biology; Gene; Gene expression","score_opus":0.006434924328956417,"score_gpt":0.2157439486364499,"score_spread":0.20930902430749349,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394465416","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0046684435,0.00008474684,0.000005498785,0.0000021429057,0.000017006512,0.0001750544,0.9950345,0.0000035656224,0.000008996408],"genre_scores_gemma":[0.003707821,0.00001118557,0.000030759587,0.000004920363,0.000043558168,0.00045368035,0.99562716,0.0000147956125,0.00010614181],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99929553,0.0000275522,0.00023721941,0.00020655667,0.00013197481,0.0001011821],"domain_scores_gemma":[0.9995099,0.00003555501,0.0002244669,0.00014592096,0.00006149991,0.000022707249],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000023032866,0.00012421016,0.00014658882,0.000108029846,0.00002903836,0.0000052200953,0.000057716647,0.00013753343,0.80802655],"category_scores_gemma":[0.00011235999,0.00013802535,0.000026099055,0.00012051287,0.0000091195625,0.000006220354,0.000045163066,0.000074813375,0.000002814159],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014540904,0.00005497279,2.5504912e-7,0.00040713712,0.00001243968,0.000001299209,0.000029473804,0.0003984167,0.11890125,9.0313295e-9,0.8797429,0.00030642567],"study_design_scores_gemma":[0.00037707624,0.000541121,0.008354638,0.00059881294,0.000010202316,0.000016575177,0.000027278778,0.000121752746,0.016933601,5.0616853e-7,0.9728438,0.00017461677],"about_ca_topic_score_codex":0.0000040164673,"about_ca_topic_score_gemma":0.000029597824,"teacher_disagreement_score":0.8080237,"about_ca_system_score_codex":0.000053073767,"about_ca_system_score_gemma":0.000037002752,"threshold_uncertainty_score":0.562851},"labels":[],"label_agreement":null},{"id":"W4394469684","doi":"10.6084/m9.figshare.20418216","title":"Additional file 4 of Target residence of Cas9-sgRNA influences DNA double-strand break repair pathway choices in CRISPR/Cas9 genome editing","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"CRISPR; Genome editing; Cas9; Subgenomic mRNA; Genetics; Computational biology; Biology; DNA; Double strand; DNA repair; Gene","score_opus":0.014709956979259552,"score_gpt":0.2766760468734021,"score_spread":0.26196608989414255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394469684","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009189872,0.0013772981,1.8581393e-7,0.000003367465,0.000060123213,0.00021301268,0.9981095,0.000011102407,0.00013347565],"genre_scores_gemma":[0.00016362735,0.000040567986,0.00015933943,0.000028906956,0.00039249193,0.00065323466,0.9984059,0.00002360085,0.00013233819],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983176,0.000045108296,0.0005284922,0.0004902187,0.0003362671,0.0002823146],"domain_scores_gemma":[0.99870527,0.00022905809,0.00038700484,0.0004809261,0.00012487215,0.00007288405],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007510788,0.00028075883,0.00036298676,0.00014368432,0.00005635293,0.0000150127225,0.0004929731,0.00029351906,0.9547238],"category_scores_gemma":[0.001146358,0.00030889458,0.00019703197,0.00018771403,0.000026843998,0.0000088862,0.00032317668,0.0003023094,0.000026506592],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003444412,0.0000361236,0.0000024193353,0.00080585433,0.00004423599,0.000031787833,0.000013870792,0.0010130614,0.00130659,4.4864944e-8,0.99668384,0.000027724967],"study_design_scores_gemma":[0.0002559364,0.0001345433,0.00066155713,0.0012511313,0.000010869978,0.000021112048,0.000047378442,0.000010916428,0.0064141825,0.0000014831754,0.99090624,0.000284648],"about_ca_topic_score_codex":0.00009868756,"about_ca_topic_score_gemma":0.0003172595,"teacher_disagreement_score":0.95469725,"about_ca_system_score_codex":0.000021061127,"about_ca_system_score_gemma":0.0002757554,"threshold_uncertainty_score":0.99993634},"labels":[],"label_agreement":null},{"id":"W4394540992","doi":"10.6084/m9.figshare.21069660","title":"Additional file 2 of Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Transcriptome; Germline; Genetics; Mutation; Biology; Germline mutation; Immune dysregulation; Immune system; Computational biology; Gene; Gene expression","score_opus":0.006328162909259181,"score_gpt":0.21560500609587083,"score_spread":0.20927684318661163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394540992","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0046117906,0.0000855124,0.000005370245,0.0000021418548,0.000016949156,0.0001747674,0.9950908,0.0000035683686,0.000009123998],"genre_scores_gemma":[0.0036231033,0.000011302019,0.000030498766,0.000004925499,0.000043690052,0.00045368235,0.9957133,0.000014783544,0.00010470414],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99929565,0.000027567163,0.00023721924,0.00020650179,0.00013192324,0.000101156846],"domain_scores_gemma":[0.9995104,0.00003539482,0.00022470581,0.00014587007,0.000060917788,0.000022706086],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002293394,0.0001241914,0.00014660665,0.00010800037,0.000029042347,0.000005220532,0.000057720514,0.00013754424,0.8088393],"category_scores_gemma":[0.00011122147,0.00013801709,0.000026096166,0.00012047119,0.000009118893,0.0000062198683,0.000045185887,0.00007481183,0.0000027622548],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014427719,0.000055092973,2.483119e-7,0.0004051667,0.000012474275,0.0000013186293,0.000029554367,0.00040076926,0.115807176,9.236345e-9,0.8828335,0.00031044945],"study_design_scores_gemma":[0.000373927,0.0005405909,0.00826342,0.0005921766,0.00001022652,0.000016703041,0.000027087965,0.00012060545,0.01649911,5.0715215e-7,0.97338176,0.00017387926],"about_ca_topic_score_codex":0.00000401178,"about_ca_topic_score_gemma":0.000029574172,"teacher_disagreement_score":0.8088366,"about_ca_system_score_codex":0.000052905176,"about_ca_system_score_gemma":0.0000368438,"threshold_uncertainty_score":0.56281734},"labels":[],"label_agreement":null},{"id":"W4394551710","doi":"10.6084/m9.figshare.20375872","title":"Additional file 6 of Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Epigenetics; Genetics; X-inactivation; Chromosome; Biology; X chromosome; Gene","score_opus":0.008914804891470658,"score_gpt":0.2512775525324561,"score_spread":0.24236274764098545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394551710","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006763275,0.00061794755,0.000003268252,0.000010312724,0.000031134656,0.0002150385,0.9990445,0.0000033284,0.000006867998],"genre_scores_gemma":[0.00015324891,0.00004804309,0.00015436152,0.000049134836,0.00017318974,0.00076039624,0.99861497,0.000015170955,0.000031505373],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99921656,0.000026952943,0.0001893175,0.00028318304,0.0001584131,0.00012559384],"domain_scores_gemma":[0.9992361,0.00014943448,0.00017052193,0.00027864872,0.00010739753,0.00005790278],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00001217854,0.00015911934,0.00020645671,0.000076563345,0.000029731087,0.0000063714724,0.000156824,0.00017745947,0.9821988],"category_scores_gemma":[0.001124322,0.0001859262,0.000049240112,0.00008747739,0.000008152876,0.0000011910005,0.00024125287,0.00008785668,0.000029588411],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013604833,0.000020597827,2.5836692e-7,0.0001093345,0.00004059959,0.0000013235683,0.000003527353,0.00006655241,0.006525902,1.8494104e-8,0.99266326,0.0005550263],"study_design_scores_gemma":[0.000108837914,0.00025053043,0.0010851464,0.00045473702,0.000017444647,0.0000030451283,0.000008052203,0.0000080108985,0.015962236,0.00000232486,0.9819286,0.00017106986],"about_ca_topic_score_codex":0.000025018777,"about_ca_topic_score_gemma":0.00009200589,"teacher_disagreement_score":0.9821692,"about_ca_system_score_codex":0.000014915144,"about_ca_system_score_gemma":0.00006580959,"threshold_uncertainty_score":0.758185},"labels":[],"label_agreement":null},{"id":"W4394692702","doi":"10.7554/elife.91288.2","title":"Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Haematopoiesis; Progenitor cell; Stem cell; Progenitor; Cell biology; Computer science; Computational biology; Biology","score_opus":0.009580305750498674,"score_gpt":0.2943217909685183,"score_spread":0.2847414852180196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394692702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991602,0.006226176,0.00027078798,0.000030354156,0.00085191405,0.00034690477,0.000076663244,0.000030558687,0.0005646624],"genre_scores_gemma":[0.99737704,0.000114733186,0.00080854417,0.000022455051,0.0010483832,0.000049871076,0.00006170577,0.00005820868,0.00045907497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878377,0.000028554427,0.00029431877,0.00049967883,0.00018669423,0.00020696632],"domain_scores_gemma":[0.99932784,0.00001206898,0.00008383664,0.0004280108,0.00005682688,0.00009141657],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018105653,0.00025983652,0.00028120185,0.00004428682,0.00004656253,0.0000529846,0.00016626802,0.00027911508,0.0000103788925],"category_scores_gemma":[0.000017493316,0.00025445296,0.00013571695,0.000036504323,0.000058863672,6.189747e-7,0.0006360967,0.00030500605,0.00001029762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019959443,0.000059059672,0.00046977992,0.0019537555,0.00019259848,0.000011713776,0.0004520638,0.0031241744,0.987995,0.000032318472,0.004767102,0.0009224658],"study_design_scores_gemma":[0.00014291037,0.00018767225,0.00007427852,0.00030582614,0.000049573326,0.000007046622,0.00006189672,0.00043610003,0.9956754,0.00004967048,0.0027722693,0.0002373514],"about_ca_topic_score_codex":0.00000668543,"about_ca_topic_score_gemma":0.0000024387168,"teacher_disagreement_score":0.007680396,"about_ca_system_score_codex":0.00001032137,"about_ca_system_score_gemma":0.000068909736,"threshold_uncertainty_score":0.99999076},"labels":[],"label_agreement":null},{"id":"W4394692856","doi":"10.1101/2024.04.09.588775","title":"Harnessing RNA-based DNA repair pathways for targeted gene editing","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Computational biology; Gene; DNA; Genome editing; RNA; Biology; Genetics; CRISPR","score_opus":0.010559703233025443,"score_gpt":0.2426542924709404,"score_spread":0.23209458923791496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394692856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9292489,0.009404194,0.054621197,0.00015450582,0.0039589982,0.0010294007,0.0008582689,0.00070800283,0.000016492198],"genre_scores_gemma":[0.9648867,0.0000843673,0.030842198,0.00019399337,0.0032170776,0.00045300616,0.000012465765,0.00029827878,0.000011892433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969495,0.000057650363,0.00058731064,0.0014144066,0.00026739587,0.00072374725],"domain_scores_gemma":[0.9978507,0.00003129969,0.00022946166,0.0012436509,0.00038705676,0.000257791],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006011147,0.00068211945,0.00049414113,0.00020564086,0.00017934946,0.00021007565,0.0004442788,0.0008027352,0.000011038126],"category_scores_gemma":[0.00033246275,0.00077385333,0.0005111661,0.00023484095,0.00007781249,0.00000502878,0.00060239364,0.00054228335,0.0000158082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031076812,0.00004938983,0.00013412196,0.0010603291,0.00020544649,0.000026913405,0.0000044577105,0.0021131514,0.99471295,0.00007110367,0.001583677,0.0000074095346],"study_design_scores_gemma":[0.0004753719,0.000091761955,0.0008430327,0.00039592647,0.0001815725,3.219335e-8,0.0000031524573,0.0061944253,0.97930306,0.0000053542776,0.011663063,0.00084323896],"about_ca_topic_score_codex":0.0000090676285,"about_ca_topic_score_gemma":0.000001926792,"teacher_disagreement_score":0.03563778,"about_ca_system_score_codex":0.00010849384,"about_ca_system_score_gemma":0.00068719755,"threshold_uncertainty_score":0.99947125},"labels":[],"label_agreement":null},{"id":"W4394724484","doi":"10.1016/j.healun.2024.02.022","title":"CRISPR-Cas Genome Editing in Ex Vivo Human Lungs","year":2024,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"CRISPR; Ex vivo; Genome editing; Biology; Genome; Genetics; Human genome; Computational biology; Gene; In vivo","score_opus":0.005910863519720297,"score_gpt":0.3040681316903437,"score_spread":0.2981572681706234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394724484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981109,0.0066860686,0.011560511,0.0003193587,0.00015548772,0.000048744223,0.0000039562706,0.0000033384651,0.00011348731],"genre_scores_gemma":[0.99799013,0.0014056937,0.00014595034,0.000040839856,0.000351544,5.6591335e-7,0.0000069460407,0.0000080455775,0.000050265055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995952,0.000027174918,0.00016556434,0.000057457077,0.00006863518,0.00008596514],"domain_scores_gemma":[0.9998787,0.000015887566,0.000019896124,0.000042580083,0.000017146493,0.00002575549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000332001,0.000057648358,0.000067311164,0.000052542953,0.000037381607,0.000020507123,0.000043316777,0.00003644493,0.000008776793],"category_scores_gemma":[0.0000032272224,0.000042180087,0.00003292527,0.00004312148,0.000015977612,0.000006449063,0.000004602474,0.00010322567,5.557388e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000334096,0.000005096141,0.00080162607,0.000115630966,0.000020611385,0.000011495196,0.0010956454,0.00064658513,0.9968316,0.000020569742,0.00027474627,0.00014299818],"study_design_scores_gemma":[0.0012990222,0.000595724,0.11388459,0.0005507711,0.0003489574,0.0027132267,0.00087886583,0.0024004078,0.8617815,0.00023009708,0.014981787,0.00033507578],"about_ca_topic_score_codex":0.00001194911,"about_ca_topic_score_gemma":0.00003196283,"teacher_disagreement_score":0.1350501,"about_ca_system_score_codex":0.000005725494,"about_ca_system_score_gemma":0.000012912266,"threshold_uncertainty_score":0.1720054},"labels":[],"label_agreement":null},{"id":"W4394727560","doi":"10.1016/j.cell.2024.03.020","title":"Chromatin context-dependent regulation and epigenetic manipulation of prime editing","year":2024,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Human Genome Research Institute; Natural Sciences and Engineering Research Council of Canada; Washington Research Foundation; Damon Runyon Cancer Research Foundation","keywords":"Chromatin; Biology; Genome editing; Context (archaeology); Prime (order theory); Computational biology; Epigenetics; Genetics; RNA editing; Histone; CRISPR; DNA; RNA; Gene","score_opus":0.0070185877673852965,"score_gpt":0.25743437806212555,"score_spread":0.25041579029474026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394727560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9404769,0.009909652,0.04837337,0.000026333504,0.00019334648,0.000101798905,0.0000039119495,0.000014025873,0.0009006431],"genre_scores_gemma":[0.9986439,0.00009045455,0.0005730902,0.0000061921633,0.00017795559,0.0000033669355,0.000030540727,0.000011647599,0.00046286217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99960375,0.000009079776,0.000116862124,0.00014184011,0.00005748305,0.00007096719],"domain_scores_gemma":[0.99983275,0.0000064458595,0.00001953427,0.00010240792,0.000016687332,0.00002215348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000077322526,0.000058687783,0.00005773741,0.000024381705,0.0000148554345,0.000012621448,0.00002860731,0.0000520888,0.00001611135],"category_scores_gemma":[0.000009269617,0.00006003749,0.000027233738,0.000027642074,0.000014257201,0.0000017102266,0.00002732577,0.00002626323,0.000003370559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000023803284,0.0000052495393,0.00017585332,0.00010571025,0.000010117821,5.7221337e-7,0.0000710444,0.0008455188,0.98843235,0.000036298337,0.00009427676,0.010220615],"study_design_scores_gemma":[0.00010779535,0.000055997218,0.0050791968,0.000029022916,0.000015470307,0.000004711927,0.00004815132,0.005633103,0.986408,0.00007080403,0.0024834648,0.00006431307],"about_ca_topic_score_codex":0.00000686213,"about_ca_topic_score_gemma":0.0000053324975,"teacher_disagreement_score":0.058166973,"about_ca_system_score_codex":0.0000045056054,"about_ca_system_score_gemma":0.000012475218,"threshold_uncertainty_score":0.24482578},"labels":[],"label_agreement":null},{"id":"W4394772365","doi":"10.5376/jmr.2024.14.0002","title":"The Impact of Releasing&lt;i&gt; Aedes aegypti&lt;/i&gt; Mosquitoes Edited by CRISPR in The Wild on Local Ecosystems","year":2024,"lang":"en","type":"article","venue":"Journal of Mosquito Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Aedes aegypti; Dengue fever; Biology; Vector (molecular biology); Ecology; Aedes; CRISPR; Ecosystem; Larva; Virology; Gene; Genetics","score_opus":0.020147101425239032,"score_gpt":0.38341911352921654,"score_spread":0.3632720121039775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394772365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96791536,0.026717357,0.001601488,0.0015198683,0.0007749966,0.00030509368,0.000029968684,0.0000067816486,0.0011291022],"genre_scores_gemma":[0.99446523,0.003756288,0.000029876313,0.00001787996,0.0012692406,0.000012577052,0.000009189679,0.000036067147,0.0004036477],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.997092,0.00047624207,0.00061204104,0.00026351603,0.0010007701,0.0005553976],"domain_scores_gemma":[0.9984248,0.000498028,0.00010906774,0.0004902782,0.00034586355,0.00013192155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035515272,0.0001979273,0.00026305288,0.00023828499,0.00016608094,0.00020131422,0.0008321413,0.00019097455,0.0000138237],"category_scores_gemma":[0.00054282387,0.0001071815,0.00029970202,0.00050766254,0.00021572375,0.000012274336,0.00013046742,0.00072860625,0.000007191135],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026619105,0.00011439732,0.00009711455,0.000070394366,0.00015252107,0.00004676917,0.00026130182,0.00439959,0.77398473,0.00015222229,0.21171822,0.008736524],"study_design_scores_gemma":[0.0017810378,0.008360446,0.006521136,0.0012312316,0.00007517216,0.0006892248,0.002119228,0.021104855,0.3216587,0.0005453644,0.6353303,0.0005832593],"about_ca_topic_score_codex":0.000057744946,"about_ca_topic_score_gemma":0.00011801766,"teacher_disagreement_score":0.45232606,"about_ca_system_score_codex":0.00013264826,"about_ca_system_score_gemma":0.00033036608,"threshold_uncertainty_score":0.43707347},"labels":[],"label_agreement":null},{"id":"W4394772432","doi":"10.5376/ijmms.2024.14.0006","title":"Application and Prospects of Gene Editing Technology in the Treatment of Neurological Disorders","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Medical Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genome editing; Medicine; Neuroscience; Intensive care medicine; Gene; Biology; CRISPR","score_opus":0.003356072463516372,"score_gpt":0.30137060177232733,"score_spread":0.29801452930881095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394772432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95887774,0.0024340516,0.035806213,0.0026582745,0.00013685555,0.00004737551,9.3932124e-7,0.0000011681022,0.000037381327],"genre_scores_gemma":[0.9987281,0.00046127065,0.00069480157,0.000036976107,0.00007254019,0.0000028343795,7.2702585e-7,0.000001877885,8.550789e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992766,0.000011360717,0.00017410779,0.000094618,0.00038037368,0.0000629569],"domain_scores_gemma":[0.9997836,0.000016766497,0.000048961127,0.000056967485,0.000065977416,0.00002778043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003132456,0.00003857308,0.00005983479,0.00010467782,0.000007792453,0.000007748182,0.00028690146,0.000039850336,0.0000015761541],"category_scores_gemma":[0.0001953325,0.000024186416,0.000031075946,0.00015530974,0.00024120737,0.0000031809343,0.000027391017,0.000054309843,7.694255e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000132648875,0.00009257749,0.0041632284,0.000005999072,0.000015714937,0.000040819705,0.00010607344,0.0003138672,0.9330625,0.0012991069,0.0000047935077,0.06088208],"study_design_scores_gemma":[0.00063197984,0.0016981303,0.015130474,0.00007191378,0.000017664357,0.00056685746,0.00013710964,0.008288129,0.9666574,0.0024618555,0.00425688,0.0000816297],"about_ca_topic_score_codex":0.0000029742857,"about_ca_topic_score_gemma":0.0000025738007,"teacher_disagreement_score":0.06080045,"about_ca_system_score_codex":0.000007299537,"about_ca_system_score_gemma":0.0000654555,"threshold_uncertainty_score":0.09862935},"labels":[],"label_agreement":null},{"id":"W4394790116","doi":"10.1101/2024.04.10.588881","title":"Seed sequences mediate off-target activity in the CRISPR-interference (CRISPRi) system","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Roche (Canada)","funders":"Genentech","keywords":"CRISPR; CRISPR interference; Interference (communication); Computational biology; Computer science; Chemistry; Biology; Genetics; Genome editing; Computer network; Gene","score_opus":0.010160127732626771,"score_gpt":0.2547905742150947,"score_spread":0.24463044648246793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394790116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98228323,0.008584535,0.0055316505,0.0003395827,0.0020109774,0.00076574343,0.00024740258,0.00017524866,0.00006162242],"genre_scores_gemma":[0.9972579,0.00057943194,0.0008780253,0.000103925755,0.0007630322,0.00030246022,0.0000012960949,0.00010537642,0.000008576406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971505,0.00023067884,0.00047467175,0.0011666709,0.00035984645,0.0006176583],"domain_scores_gemma":[0.99806184,0.000042964348,0.00018132087,0.0013893049,0.0001708846,0.00015371693],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009347238,0.00062374317,0.0004927127,0.00019108053,0.00008826696,0.0002518298,0.0010259768,0.0006291132,0.000007153965],"category_scores_gemma":[0.00013573932,0.00053070625,0.0002198623,0.00034918915,0.000112742346,0.00000769795,0.00087884953,0.0010109314,0.00004259032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038049453,0.000057816418,0.0019348137,0.0010334078,0.00014102047,0.000097938064,0.00003489799,0.0008298169,0.9952888,0.00015532554,0.0003830586,0.0000050658614],"study_design_scores_gemma":[0.00031828583,0.000113486385,0.025276015,0.0007214051,0.00012086797,2.4189958e-7,0.000044402535,0.0032894106,0.9655846,0.000005403023,0.0036049474,0.00092095],"about_ca_topic_score_codex":0.00009792963,"about_ca_topic_score_gemma":0.000026298372,"teacher_disagreement_score":0.029704204,"about_ca_system_score_codex":0.0001337971,"about_ca_system_score_gemma":0.0004413332,"threshold_uncertainty_score":0.99971443},"labels":[],"label_agreement":null},{"id":"W4394861821","doi":"10.5376/ijmms.2024.14.0007","title":"The Development and Clinical Transformation of Gene Therapy in Cardiovascular Diseases","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Medical Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genetic enhancement; Medicine; Disease; Clinical trial; Intensive care medicine; Bioinformatics; Gene; Pathology; Biology; Genetics","score_opus":0.009694112682554297,"score_gpt":0.3487197172244746,"score_spread":0.33902560454192027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394861821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92606175,0.016572688,0.056314208,0.0005236475,0.00044482385,0.00003323248,7.8398614e-7,0.0000011206879,0.00004773029],"genre_scores_gemma":[0.99699855,0.002235292,0.00063032034,0.000041931846,0.0000869219,9.856006e-7,0.0000010052354,0.0000026430569,0.0000023621283],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877435,0.00002712501,0.0003203214,0.00008770656,0.00071648986,0.000074006755],"domain_scores_gemma":[0.99968183,0.000027996532,0.00003122907,0.000060061386,0.00011949788,0.00007936592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013853185,0.000041480722,0.00007503103,0.00005933954,0.000018431192,0.000028788585,0.00031091436,0.00003189804,0.0000022100276],"category_scores_gemma":[0.00029421732,0.000026429152,0.00009155085,0.00008236395,0.00019019353,0.0000072763382,0.00003199344,0.00007787707,2.0377716e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059720216,0.000055981058,0.0019643584,0.000009577597,0.00027924025,0.00009386035,0.00023918004,0.0006602712,0.13188085,0.00030034786,0.000022699453,0.8644339],"study_design_scores_gemma":[0.0014298302,0.00038542016,0.067379214,0.00025016235,0.000032851232,0.00039063251,0.00018773266,0.0040768916,0.8624518,0.00026221797,0.06296946,0.0001837905],"about_ca_topic_score_codex":0.0000018054901,"about_ca_topic_score_gemma":0.0000025786505,"teacher_disagreement_score":0.8642501,"about_ca_system_score_codex":0.000012429434,"about_ca_system_score_gemma":0.00033150282,"threshold_uncertainty_score":0.10777496},"labels":[],"label_agreement":null},{"id":"W4394932258","doi":"10.20944/preprints202401.1948.v2","title":"CRISPR/CAS Genome Editing Technology: Implications And Challenges","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Computer science; Genome; Biology; Data science; Genetics; Gene","score_opus":0.07024387818540614,"score_gpt":0.3698412558213853,"score_spread":0.29959737763597916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394932258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9332077,0.05280018,0.0012722244,0.006426558,0.0005857998,0.0004651545,0.00006804583,0.00021235233,0.0049619866],"genre_scores_gemma":[0.98130506,0.016635465,0.00050933077,0.000044374727,0.00072281045,0.0002494388,0.00008739008,0.00006711162,0.00037904162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981707,0.000021747004,0.00029713177,0.0010943171,0.00009532765,0.00032077893],"domain_scores_gemma":[0.99858034,0.0000095304495,0.00008442476,0.0011314217,0.00008997699,0.00010432947],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025186109,0.00032225897,0.0002557205,0.00017339691,0.000075181786,0.000023668548,0.00040127774,0.00060390204,0.000030468376],"category_scores_gemma":[0.00013255158,0.00035720278,0.00011446446,0.0000836275,0.00010416765,0.0000015503352,0.0039059895,0.00062601746,0.00013079413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010035557,0.0000619147,0.03257851,0.0011710457,0.00040340176,0.000011286069,0.00046352707,0.0006858689,0.9553559,0.0015692578,0.000111843336,0.007577444],"study_design_scores_gemma":[0.0003015806,0.000068669775,0.23723851,0.00027155818,0.0002270411,0.0001461762,0.00054504996,0.00011524917,0.61947495,0.013621829,0.12689519,0.0010941747],"about_ca_topic_score_codex":0.000009878814,"about_ca_topic_score_gemma":0.000017961975,"teacher_disagreement_score":0.3358809,"about_ca_system_score_codex":0.00002806196,"about_ca_system_score_gemma":0.00006814517,"threshold_uncertainty_score":0.999888},"labels":[],"label_agreement":null},{"id":"W4395037406","doi":"10.1101/2024.04.20.590404","title":"A scalable CRISPR-Cas9 gene editing system facilitates CRISPR screens in the malaria parasite <i>Plasmodium berghei</i>","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"Xiamen University; Umeå Universitet; Vetenskapsrådet; Japan Society for the Promotion of Science; Cancerfonden; Massachusetts Institute of Technology","keywords":"CRISPR; Plasmodium berghei; Genome editing; Biology; Malaria; Cas9; Computational biology; Parasite hosting; Gene; Subgenomic mRNA; Genetics; Virology; Computer science; World Wide Web; Immunology","score_opus":0.008758645378082595,"score_gpt":0.24223029645840094,"score_spread":0.23347165108031834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395037406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9725892,0.0132228695,0.00857175,0.0005286987,0.002491009,0.0012890125,0.0009110021,0.00029404013,0.000102411206],"genre_scores_gemma":[0.9941488,0.0003063083,0.0031625475,0.0002159108,0.0015149702,0.00043715737,0.0000071498775,0.00018366391,0.000023513712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99598473,0.00022298115,0.0008103342,0.0015280838,0.00048253604,0.0009713046],"domain_scores_gemma":[0.9974829,0.000056907535,0.0002114332,0.0017418246,0.0002817819,0.00022517926],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012713753,0.0008445813,0.0006382599,0.0002518721,0.00018251702,0.00038136265,0.0009719134,0.00085509475,0.0000088212355],"category_scores_gemma":[0.00015689523,0.00077959517,0.0003191246,0.0004891845,0.00011962296,0.000010648925,0.0010380611,0.0011574321,0.00008112144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041719293,0.00008569842,0.0036281757,0.0015383798,0.0002634614,0.00019727284,0.000044732806,0.0027181685,0.9879501,0.00035223123,0.0031774594,0.0000025984543],"study_design_scores_gemma":[0.0006745167,0.00013006068,0.02038552,0.0009893299,0.0003046038,0.0000011136643,0.000109172004,0.0035128088,0.9586726,0.000004265946,0.013822439,0.0013936086],"about_ca_topic_score_codex":0.00026859093,"about_ca_topic_score_gemma":0.00003074814,"teacher_disagreement_score":0.02927754,"about_ca_system_score_codex":0.0001452423,"about_ca_system_score_gemma":0.00031349502,"threshold_uncertainty_score":0.9994655},"labels":[],"label_agreement":null},{"id":"W4395074133","doi":"10.2174/9789815223798124010004","title":"Genome Editing Against Bacterial Plant Pathogens","year":2024,"lang":"en","type":"book-chapter","venue":"BENTHAM SCIENCE PUBLISHERS eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Genome; Computational biology; Bacterial genome size; Genetics; Evolutionary biology; Gene","score_opus":0.010023725757511625,"score_gpt":0.24177654881323174,"score_spread":0.23175282305572012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395074133","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013887443,0.00069163827,0.00016810748,0.0000604554,0.0041970033,0.0003583659,0.00036101477,0.000087013075,0.98018897],"genre_scores_gemma":[0.19906725,0.00007079419,0.0007216626,0.00028671362,0.0075917193,0.000055691886,0.0015507529,0.00027026454,0.7903851],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974262,0.000005441608,0.00036755946,0.0010373896,0.00053838786,0.0006250274],"domain_scores_gemma":[0.9988022,0.0000069616967,0.00011982147,0.0006347802,0.00013567417,0.00030059137],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004782863,0.00043458206,0.00026711822,0.00029251125,0.00019308813,0.0009325791,0.0007873033,0.00036428464,0.00008862667],"category_scores_gemma":[0.000054875505,0.0004315416,0.00021318033,0.00004486075,0.00043754737,0.000018347106,0.0005957306,0.0003282605,0.000046974095],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017775395,0.000009171981,0.0000065737295,0.00009591123,0.00009827211,0.000071080474,0.000188169,0.00013153086,0.9833155,0.0035128368,0.0061651394,0.0063880356],"study_design_scores_gemma":[0.00018572548,0.000110989444,0.00003889315,0.00010676943,0.00005200565,0.000046573736,0.00007190304,0.0000599832,0.02123688,0.00039755862,0.97701454,0.00067815976],"about_ca_topic_score_codex":0.000003482815,"about_ca_topic_score_gemma":0.0000189918,"teacher_disagreement_score":0.9708494,"about_ca_system_score_codex":0.000079669524,"about_ca_system_score_gemma":0.00040330473,"threshold_uncertainty_score":0.9998136},"labels":[],"label_agreement":null},{"id":"W4395074959","doi":"10.1038/s41588-024-01726-6","title":"Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification","year":2024,"lang":"en","type":"article","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Health and Medical Research Council; State Government of Victoria; National Organization for Rare Disorders; National Institute of Environmental Health Sciences; American Cancer Society; National Institute of General Medical Sciences; Medical Research Council; American Heart Association; U.S. Department of Health and Human Services","keywords":"Biology; Computational biology; Genome editing; Phenotype; Genetics; Bayes' theorem; Cas9; Gene; CRISPR; Computer science; Bayesian probability; Artificial intelligence","score_opus":0.010012102327567163,"score_gpt":0.29328591061632714,"score_spread":0.28327380828876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395074959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81150126,0.042058755,0.14463834,0.00014350376,0.0012349222,0.00023179186,0.000016699214,0.000058517395,0.000116194475],"genre_scores_gemma":[0.9928853,0.0004393236,0.005259429,0.0001032013,0.001055912,0.000016873255,0.00008442242,0.00004965923,0.00010587216],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9988256,0.000031376807,0.0002576443,0.0004901408,0.00013794177,0.00025726407],"domain_scores_gemma":[0.99948543,0.00001773115,0.000028692582,0.00032686323,0.000052986452,0.0000882886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003218717,0.00021518911,0.00015680828,0.0000758197,0.00007775974,0.00009698471,0.00010890817,0.0003684952,0.000004874455],"category_scores_gemma":[0.000111897265,0.00019517512,0.00008003348,0.000102699334,0.000025415446,0.0000037129448,0.00009858281,0.00035731375,0.00000688339],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017132923,0.000011412401,0.00053832564,0.00031826846,0.0000667295,0.000010660324,0.00007324492,0.009397308,0.9644092,0.00015630454,0.00021535147,0.024786102],"study_design_scores_gemma":[0.00043403878,0.0002923103,0.00296097,0.00008464051,0.00016093066,0.00008848954,0.00005137805,0.5233646,0.4649168,0.00025274314,0.00686998,0.000523126],"about_ca_topic_score_codex":0.000003862508,"about_ca_topic_score_gemma":0.000007524403,"teacher_disagreement_score":0.5139673,"about_ca_system_score_codex":0.0000142664085,"about_ca_system_score_gemma":0.000030928124,"threshold_uncertainty_score":0.79590106},"labels":[],"label_agreement":null},{"id":"W4395082447","doi":"10.7554/elife.92819.3","title":"Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de recherche du Québec – Nature et technologies; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Endogeny; Induced pluripotent stem cell; HEK 293 cells; Biology; Computational biology; Cytokinesis; Live cell imaging; Cell biology; Protein engineering; Cell culture; Cell; Genetics; Cell division; Gene; Embryonic stem cell; Biochemistry; Enzyme","score_opus":0.04514793003609745,"score_gpt":0.3819789212909155,"score_spread":0.336830991254818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395082447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9480009,0.039077412,0.011954482,0.000088274785,0.0003693935,0.00024162073,0.000016096912,0.000038227412,0.00021356536],"genre_scores_gemma":[0.99676585,0.0002580873,0.0021560488,0.00011227328,0.00047066176,0.000025557967,0.00003003126,0.000031785778,0.00014969896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999252,0.000010695116,0.00016303296,0.00026543037,0.000070040325,0.00023878817],"domain_scores_gemma":[0.99974895,0.000019258678,0.000015773338,0.00014293725,0.000039008366,0.000034070243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001760189,0.0001211641,0.00012280612,0.00006530919,0.0000661327,0.00003129951,0.00008137139,0.00004036908,0.0000032879893],"category_scores_gemma":[0.000048887207,0.0001241001,0.00007084108,0.000061748055,0.000026316477,0.0000030838153,0.000079598525,0.00006174776,0.0000034851528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000067078086,0.0000104258925,0.00095256406,0.00014818869,0.000071257295,0.000027930535,0.0006202441,0.0023869195,0.99220616,0.000097087424,0.0005305734,0.002941966],"study_design_scores_gemma":[0.0006627257,0.00013888783,0.00055886246,0.00034401144,0.000084684754,0.00010817169,0.0018672474,0.01953702,0.9207108,0.00017011593,0.055218972,0.00059847],"about_ca_topic_score_codex":0.000027369235,"about_ca_topic_score_gemma":0.00003509725,"teacher_disagreement_score":0.0714953,"about_ca_system_score_codex":0.00002891272,"about_ca_system_score_gemma":0.000030063618,"threshold_uncertainty_score":0.5060655},"labels":[],"label_agreement":null},{"id":"W4395098342","doi":"10.5376/rgg.2024.15.0002","title":"Development of CRISPR-Cas9 Multiple Editing System for Genetic Improvement of Rice","year":2024,"lang":"en","type":"article","venue":"Rice Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Biology; Cas9; Biotechnology; Computer science; Computational biology; Genetics; Gene","score_opus":0.008572562073447771,"score_gpt":0.2623255049025626,"score_spread":0.25375294282911487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395098342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80036634,0.010692285,0.18813817,0.000009999943,0.00035610885,0.00029815198,0.00007261544,0.000010534295,0.000055765282],"genre_scores_gemma":[0.9131743,0.00046602893,0.08591702,0.000010604421,0.00027770523,0.000033368444,0.00003645018,0.000037183887,0.000047354442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884725,0.0000070646915,0.00047678428,0.00033086425,0.000102819664,0.0002352116],"domain_scores_gemma":[0.9994753,0.000029493514,0.000093582006,0.00022559747,0.00010180842,0.00007418883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019483514,0.00017452592,0.00020011493,0.000066932866,0.0000579213,0.000021909422,0.00013091833,0.00010816912,8.98662e-7],"category_scores_gemma":[0.000018802584,0.00017887796,0.000081491096,0.00007356037,0.000034537494,0.0000016327937,0.0001256561,0.00004677581,7.816998e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017459175,0.00002048565,0.00013516117,0.0017159082,0.00011114969,7.6311943e-7,0.00037374906,0.0010843453,0.97756904,0.000025154593,0.00007605944,0.018870745],"study_design_scores_gemma":[0.00037578624,0.00020113161,0.001516263,0.000063527754,0.00007182203,0.0000103583625,0.0005958178,0.01021964,0.9644805,0.000012086943,0.022250444,0.0002026013],"about_ca_topic_score_codex":0.0000075324474,"about_ca_topic_score_gemma":0.000010903317,"teacher_disagreement_score":0.112807915,"about_ca_system_score_codex":0.000025893629,"about_ca_system_score_gemma":0.00011078421,"threshold_uncertainty_score":0.72944313},"labels":[],"label_agreement":null},{"id":"W4395464376","doi":"10.1093/nar/gkae281","title":"Systematic interrogation of CRISPR antimicrobials in <i>Klebsiella pneumoniae</i> reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"H2020 European Research Council; Pfizer Foundation; Joint Programming Initiative on Antimicrobial Resistance; Agence Nationale de la Recherche; Pfizer","keywords":"CRISPR; Biology; Klebsiella pneumoniae; Antimicrobial; Computational biology; Nuclease; Guide RNA; Microbiology; Genome editing; Cas9; DNA; Genetics; Gene; Escherichia coli","score_opus":0.015781241023754188,"score_gpt":0.35180002324841636,"score_spread":0.3360187822246622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395464376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966032,0.001315907,0.0007038794,0.00016616248,0.00012497575,0.00052553415,0.000053856063,0.000021862443,0.00048461743],"genre_scores_gemma":[0.99867576,0.00040452456,0.000312065,0.000033608852,0.00009318644,0.000016935173,0.000013960033,0.000042060623,0.00040789298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811757,0.0002594955,0.00043070308,0.00047958773,0.00031129573,0.00040133673],"domain_scores_gemma":[0.99925685,0.000093832714,0.000052089057,0.00037148563,0.0001387295,0.00008698451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015850841,0.00018464884,0.000322547,0.000285533,0.000067606416,0.00012228158,0.00024964532,0.0002160081,0.000013549306],"category_scores_gemma":[0.00024754263,0.00017729524,0.00008264566,0.00028668006,0.00013218327,0.00001653478,0.00028541114,0.0003549483,0.00000901328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003507092,0.000036988764,0.00040845491,0.004939072,0.000054508797,0.00002260426,0.00051185937,0.0002101959,0.9920768,0.000052724663,0.0010012401,0.0006504817],"study_design_scores_gemma":[0.00036896358,0.00020810461,0.0049431804,0.003408679,0.000026479407,0.0001198464,0.0005573385,0.00050285674,0.9893646,0.000038252078,0.00021754086,0.00024412828],"about_ca_topic_score_codex":0.00013923015,"about_ca_topic_score_gemma":0.00011236625,"teacher_disagreement_score":0.004534725,"about_ca_system_score_codex":0.000075962416,"about_ca_system_score_gemma":0.00012990889,"threshold_uncertainty_score":0.72298896},"labels":[],"label_agreement":null},{"id":"W4395465087","doi":"10.1007/s11105-024-01459-0","title":"Development of a Csy4-Processing TRV-Based CRISPR/Cas9 Genome Editing System in Nicotiana benthamiana","year":2024,"lang":"en","type":"article","venue":"Plant Molecular Biology Reporter","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; National Natural Science Foundation of China","keywords":"Nicotiana benthamiana; CRISPR; Biology; Genome editing; Cas9; Computational biology; Genome; Guide RNA; Genetics; Gene","score_opus":0.008568074725878604,"score_gpt":0.28413063221200097,"score_spread":0.27556255748612235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395465087","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7885171,0.005342613,0.20488843,0.000036589536,0.0003438992,0.00020311428,0.000032822725,0.00004745679,0.0005879328],"genre_scores_gemma":[0.9921229,0.00000983928,0.0071386853,0.000055668785,0.00012402593,0.00003721017,0.00045118897,0.00003577247,0.000024693194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828386,0.00004078645,0.00064713927,0.00055080216,0.000115331306,0.00036207886],"domain_scores_gemma":[0.9994688,0.000010327214,0.00011683517,0.0002875484,0.000043856347,0.00007263306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037814793,0.0002332182,0.00028112254,0.00019170319,0.0000388405,0.000022918295,0.00015395648,0.00023433146,0.000007783003],"category_scores_gemma":[0.000033536297,0.00022138422,0.000109889275,0.00015463795,0.00004929557,0.000003091586,0.000076920296,0.00012623881,0.0000036003607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001487572,0.000026171198,0.0020235965,0.00037891135,0.00008376377,0.00032673747,0.00012816707,0.00045480882,0.9939949,0.000052467458,0.000036160876,0.0024794645],"study_design_scores_gemma":[0.00044651222,0.0001172473,0.0025384098,0.0004435034,0.000058768594,0.00048304707,0.00027501286,0.0062630987,0.9668657,0.000011262698,0.022003038,0.000494396],"about_ca_topic_score_codex":0.000012005087,"about_ca_topic_score_gemma":0.00004639122,"teacher_disagreement_score":0.20360579,"about_ca_system_score_codex":0.000041838084,"about_ca_system_score_gemma":0.00021377507,"threshold_uncertainty_score":0.9027787},"labels":[],"label_agreement":null},{"id":"W4396241746","doi":"10.1038/s41592-024-02256-z","title":"Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput","year":2024,"lang":"en","type":"article","venue":"Nature Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; National Cancer Institute; National Science Foundation; National Institutes of Health; National Human Genome Research Institute; University of California, San Diego; Michael Smith Health Research BC; National Center for Research Resources; National Institute of General Medical Sciences; Stem Cell Network","keywords":"Phosphoproteomics; Phosphorylation; NFAT; Biology; Computational biology; Function (biology); Phenotype; Regulation of gene expression; Signal transduction; Cell biology; Protein phosphorylation; Gene; Transcription factor; Genetics; Protein kinase A","score_opus":0.01906636675796761,"score_gpt":0.3943247207630588,"score_spread":0.37525835400509117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396241746","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10666695,0.0052607707,0.8824121,0.0013014885,0.003691376,0.00024394372,0.00017173793,0.00003900324,0.00021263902],"genre_scores_gemma":[0.78241485,0.00004784372,0.2131208,0.0003565416,0.0028611636,0.000033417953,0.00085317483,0.000024341118,0.0002878542],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988936,0.0001190975,0.00020214681,0.00042192242,0.00019089508,0.00017229281],"domain_scores_gemma":[0.9994316,0.00010331065,0.00001975672,0.00023548299,0.00013811523,0.000071752664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006911089,0.00013962288,0.000113736394,0.00011655657,0.00004013312,0.000040182127,0.000095403055,0.0003322269,0.00005843078],"category_scores_gemma":[0.00024765066,0.00013812263,0.00007500565,0.0003746547,0.000014003446,0.00000826582,0.000032878248,0.00031136084,0.000015498728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001062977,0.00006647356,0.002760744,0.00007951396,0.00005891653,0.000003886325,0.00011121478,0.018843725,0.9407597,0.0017848264,0.00739601,0.028028682],"study_design_scores_gemma":[0.000617815,0.0001420396,0.22030282,0.000060141203,0.0000628988,0.000013144307,0.000046590547,0.016319074,0.39486483,0.0007445946,0.36623526,0.0005907906],"about_ca_topic_score_codex":0.000033272263,"about_ca_topic_score_gemma":0.00003553999,"teacher_disagreement_score":0.6757479,"about_ca_system_score_codex":0.000031257066,"about_ca_system_score_gemma":0.00008465901,"threshold_uncertainty_score":0.56324774},"labels":[],"label_agreement":null},{"id":"W4396495846","doi":"10.1021/acs.analchem.3c05776","title":"Detection of sgRNA via SHERLOCK as Potential CRISPR Related Gene Doping Control Strategy","year":2024,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Sporthochschule Köln; Manfred Donike Institut für Dopinganalytik; World Anti-Doping Agency","keywords":"CRISPR; Subgenomic mRNA; Recombinase Polymerase Amplification; Nucleic acid; Computational biology; Chemistry; Genome editing; Guide RNA; Polymerase chain reaction; Gene; Biology; Biochemistry","score_opus":0.003576248903292293,"score_gpt":0.2693188970110328,"score_spread":0.2657426481077405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396495846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8824359,0.0037656052,0.11037389,0.00007744573,0.0002299757,0.00008941828,0.000013710156,0.000051703002,0.0029623401],"genre_scores_gemma":[0.9983175,0.00008954467,0.00004809447,0.000021598722,0.00039481642,0.000005184192,0.000042171094,0.00002577967,0.0010553586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989974,0.000011909257,0.00028724826,0.00033832743,0.00014069544,0.00022441994],"domain_scores_gemma":[0.999556,0.000011924688,0.0000303066,0.00023711339,0.000058980095,0.00010565606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009821998,0.00015810627,0.0001652225,0.000024397343,0.000030581214,0.000029482486,0.00011382671,0.00024622056,0.000107650296],"category_scores_gemma":[0.000046235647,0.00015923339,0.00017617231,0.00012545474,0.000059423804,0.000003557086,0.000038661536,0.00017675522,0.000015712483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003365375,0.000021267497,0.00002521366,0.0001354306,0.00017903665,0.000032912943,0.000005509827,0.0026053844,0.99524975,0.000009106514,0.00010374751,0.0015990165],"study_design_scores_gemma":[0.00032086886,0.00008444562,0.00009883881,0.000024599,0.00011792974,0.00014337909,0.00002118053,0.03932209,0.95841855,0.00009666805,0.0011779467,0.00017347636],"about_ca_topic_score_codex":0.000018656128,"about_ca_topic_score_gemma":0.0000010231939,"teacher_disagreement_score":0.11588154,"about_ca_system_score_codex":0.000016954571,"about_ca_system_score_gemma":0.00005162435,"threshold_uncertainty_score":0.6493349},"labels":[],"label_agreement":null},{"id":"W4396616763","doi":"10.3390/cimb46050255","title":"Recent Therapeutic Gene Editing Applications to Genetic Disorders","year":2024,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"Health Canada; Government of Canada","keywords":"Genome editing; CRISPR; Cas9; Computational biology; Genetic enhancement; Transcription activator-like effector nuclease; Biology; Computer science; Bioinformatics; Gene; Genetics","score_opus":0.02543826433593848,"score_gpt":0.4410707447389453,"score_spread":0.4156324804030068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396616763","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000018283346,0.918728,0.07858038,0.00008417268,0.0011566959,0.0012408674,0.00006915008,0.00003569221,0.00008679008],"genre_scores_gemma":[0.00006592095,0.99438226,0.002210219,0.00005567559,0.00089250656,0.0012497741,0.0009573349,0.00012041932,0.00006588441],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975542,0.00015912771,0.0006156248,0.001031002,0.00010264792,0.00053743896],"domain_scores_gemma":[0.9989721,0.000014693154,0.00009426186,0.00074503047,0.000042043113,0.0001318372],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016639284,0.00056550227,0.000778899,0.0003065191,0.00003898324,0.000035554058,0.00056977145,0.00043547113,0.000016950224],"category_scores_gemma":[0.000048601254,0.00051788474,0.00033371022,0.0004854419,0.00007100749,0.0000010441107,0.00040363194,0.00039575403,0.00013640456],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000016945936,0.000046648245,0.0000072592516,0.0016484723,0.00010649517,0.0000033788024,0.00001908319,0.000077545024,0.0015870435,0.00015084568,0.0003601046,0.9959914],"study_design_scores_gemma":[0.000083215986,0.00009901381,0.0000017205622,0.000801945,0.00026564178,0.00001747507,0.000006672366,0.000011285221,0.00052035396,0.0003281009,0.9973626,0.0005019406],"about_ca_topic_score_codex":0.000003964391,"about_ca_topic_score_gemma":0.000018066119,"teacher_disagreement_score":0.99700254,"about_ca_system_score_codex":0.00005620599,"about_ca_system_score_gemma":0.00011187837,"threshold_uncertainty_score":0.99972725},"labels":[],"label_agreement":null},{"id":"W4396620965","doi":"10.14814/phy2.15977","title":"Disruption of the c‐terminal serine protease domain of <i>Fam111a</i> does not alter calcium homeostasis in mice","year":2024,"lang":"en","type":"article","venue":"Physiological Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Frameshift mutation; Serine protease; Calcium metabolism; Homeostasis; Proteases; Serine; Biology; Mutant; Endocrinology; Internal medicine; Mutation; Chemistry; Calcium; Protease; Molecular biology; Cell biology; Genetics; Gene; Biochemistry; Medicine; Phosphorylation; Enzyme","score_opus":0.012091852719882317,"score_gpt":0.308433630763488,"score_spread":0.2963417780436057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396620965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984072,0.00041894804,0.0006272599,0.000090014284,0.00017088008,0.00019519065,0.00001843477,0.0000069175885,0.0000651916],"genre_scores_gemma":[0.99947315,0.000054183427,0.00021607602,0.00003615765,0.00009085069,0.000030064823,0.000017934944,0.000007991452,0.0000735961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991661,0.000034753935,0.00030463832,0.0002569101,0.0001027021,0.00013491767],"domain_scores_gemma":[0.9996219,0.000010873164,0.000070974296,0.00023911694,0.000025895444,0.000031234642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014845112,0.000103151375,0.00015128736,0.000020487394,0.000012855176,0.0000051544653,0.00007928652,0.00007454888,0.00001180724],"category_scores_gemma":[0.00007293528,0.000056035104,0.00011975239,0.00009300175,0.00007530709,0.0000025424185,0.00012031782,0.00008175236,4.238099e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039998395,0.000050102823,0.00074414327,0.00012982507,0.000012400436,0.0000529838,0.000028686703,0.00029828932,0.9973387,0.000018075978,0.000054544424,0.0012322656],"study_design_scores_gemma":[0.00006847376,0.000114471746,0.034387305,0.00006207247,0.000009719591,0.00006318033,0.000020818214,0.00007250664,0.96393156,0.0003943386,0.00078930164,0.00008626244],"about_ca_topic_score_codex":0.000029188617,"about_ca_topic_score_gemma":0.0000073316664,"teacher_disagreement_score":0.033643164,"about_ca_system_score_codex":0.000007196858,"about_ca_system_score_gemma":0.000025332876,"threshold_uncertainty_score":0.22850452},"labels":[],"label_agreement":null},{"id":"W4396697101","doi":"10.1002/anie.202407862","title":"Inside Cover: A Sensitive Technique Unravels the Kinetics of Activation and <i>Trans</i> ‐Cleavage of CRISPR‐Cas Systems (Angew. Chem. Int. Ed. 22/2024)","year":2024,"lang":"en","type":"paratext","venue":"Angewandte Chemie International Edition","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Kinetics; Chemistry; Ribonucleoprotein; Nucleic acid; CRISPR; Cleavage (geology); Reaction rate constant; Dissociation constant; INT; RNA; Stereochemistry; Biophysics; Biochemistry; Materials science; Biology; Physics; Computer science","score_opus":0.007496362484837817,"score_gpt":0.2824248628758148,"score_spread":0.274928500390977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396697101","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015531121,0.005170696,0.9455503,0.00047289094,0.0043373685,0.0008600259,0.0026391463,0.000021522645,0.0393949],"genre_scores_gemma":[0.98255223,0.0054089585,0.00016262798,0.00010859562,0.0020299659,0.00010698635,0.0031194254,0.00005847125,0.006452711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986523,0.00002882492,0.00044995532,0.00038292914,0.0003319727,0.00015402208],"domain_scores_gemma":[0.99900305,0.00006428978,0.00026845335,0.00025854455,0.00036041412,0.000045242316],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016670156,0.0002908706,0.00029996684,0.0001249866,0.000024994652,0.00004061999,0.00019529504,0.00043439114,0.000068386726],"category_scores_gemma":[0.000078520396,0.00025729404,0.00013656385,0.000112934926,0.00014255483,0.00001125737,0.00013183449,0.00030305865,0.000013221337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048561164,0.000032722302,0.0000023229484,0.00039816886,0.00019959183,0.000001872332,0.00012465839,0.00019909606,0.7408223,0.000019675941,0.25804862,0.00010238736],"study_design_scores_gemma":[0.00023238102,0.00010756803,0.000026749402,0.0005998737,0.00008646075,0.00004295942,0.0001740578,0.000041147076,0.8755777,0.000028693736,0.12287629,0.00020616005],"about_ca_topic_score_codex":0.0000778912,"about_ca_topic_score_gemma":0.000003296965,"teacher_disagreement_score":0.9809992,"about_ca_system_score_codex":0.00006075187,"about_ca_system_score_gemma":0.000061065606,"threshold_uncertainty_score":0.9999879},"labels":[],"label_agreement":null},{"id":"W4396705467","doi":"10.1002/ange.202407862","title":"Innentitelbild: A Sensitive Technique Unravels the Kinetics of Activation and <i>Trans</i> ‐Cleavage of CRISPR‐Cas Systems (Angew. Chem. 22/2024)","year":2024,"lang":"de","type":"article","venue":"Angewandte Chemie","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Kinetics; Chemistry; Nucleic acid; CRISPR; Ribonucleoprotein; Cleavage (geology); Reaction rate constant; Dissociation constant; RNA; Biophysics; Dissociation (chemistry); Stereochemistry; Receptor–ligand kinetics; Biochemistry; Biology; Physical chemistry; Physics","score_opus":0.007949954743111304,"score_gpt":0.26894915748469145,"score_spread":0.26099920274158017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396705467","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06799501,0.10805265,0.8136451,0.00091797416,0.0017008781,0.0020267519,0.0009442064,0.00007421402,0.0046431837],"genre_scores_gemma":[0.9932343,0.005123262,0.0002881057,0.000049049468,0.000490826,0.000042742104,0.00014766998,0.0000613334,0.0005627342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984602,0.00004567563,0.0004961044,0.00046830467,0.000230989,0.0002987334],"domain_scores_gemma":[0.9990575,0.000084943844,0.00013793002,0.00046664124,0.0001696799,0.00008333206],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028807105,0.00033810083,0.00038358805,0.00009875811,0.00004151955,0.00005837468,0.00017975389,0.00037972123,0.000011056366],"category_scores_gemma":[0.00006561564,0.00028694648,0.00016455892,0.0003305209,0.0002569811,0.000010146417,0.00013717399,0.00026476028,0.0000021036371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047956728,0.000061016934,0.00005901587,0.0018297194,0.00036016476,0.000010132084,0.0007497109,0.00006499772,0.9920522,0.000068651476,0.0042095645,0.0004868892],"study_design_scores_gemma":[0.0002817619,0.00020494038,0.00009764173,0.00071988284,0.00030151548,0.000035901634,0.0005182966,0.00011401349,0.9589178,0.000022617864,0.03850622,0.00027940798],"about_ca_topic_score_codex":0.00007487737,"about_ca_topic_score_gemma":0.000003954067,"teacher_disagreement_score":0.92523926,"about_ca_system_score_codex":0.00003065685,"about_ca_system_score_gemma":0.000060511702,"threshold_uncertainty_score":0.9999583},"labels":[],"label_agreement":null},{"id":"W4396747363","doi":"10.1089/hum.2023.223","title":"CRISPR-Cas Genome Editing in <i>Ex Vivo</i> Human Lungs to Rewire the Translational Path of Genome-Targeting Therapeutics","year":2024,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Toronto General Hospital; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; University Health Network Foundation; Canadian Society of Transplantation; Hospital for Sick Children; University of Toronto","keywords":"Genome editing; Ex vivo; Genome; CRISPR; Biology; Computational biology; Genetics; Gene; In vivo","score_opus":0.016617002378730938,"score_gpt":0.31676334598167866,"score_spread":0.30014634360294773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396747363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9720466,0.01817402,0.008155142,0.00032950522,0.0001585087,0.0003622399,0.000041142095,0.00003203148,0.0007007858],"genre_scores_gemma":[0.9970789,0.0005441138,0.00052362774,0.00042208223,0.0009349298,0.00003058741,0.00012053908,0.00006409605,0.00028111014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986551,0.00005579952,0.00039300267,0.0003778977,0.0001961017,0.00032213543],"domain_scores_gemma":[0.99949944,0.000017784843,0.000048173133,0.00032341084,0.000055262422,0.00005592994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042567975,0.0002223224,0.00018379546,0.000094727395,0.00013671564,0.000048634818,0.00029835463,0.00010910287,0.00011653716],"category_scores_gemma":[0.000004254107,0.00018555748,0.00013489168,0.00018862309,0.000053489985,0.000005226137,0.000047999736,0.00016305267,0.0000045951183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018523453,0.000031798856,0.0002964746,0.000031082815,0.00008169732,0.0000050444287,0.0026139745,0.0029844034,0.9922166,0.00014128358,0.00013571754,0.0014434321],"study_design_scores_gemma":[0.00083539,0.00051282055,0.013048664,0.00006312597,0.00003653092,0.000019146231,0.00049510424,0.00049750856,0.8511198,0.0004810111,0.13232179,0.0005691118],"about_ca_topic_score_codex":0.000020588066,"about_ca_topic_score_gemma":0.00004685304,"teacher_disagreement_score":0.14109677,"about_ca_system_score_codex":0.000019123183,"about_ca_system_score_gemma":0.0000385431,"threshold_uncertainty_score":0.75668144},"labels":[],"label_agreement":null},{"id":"W4396748464","doi":"10.1039/d4bm00286e","title":"Non-viral vector-based genome editing for cancer immunotherapy","year":2024,"lang":"en","type":"article","venue":"Biomaterials Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Cancer immunotherapy; Immunotherapy; Genome; Viral vector; Computational biology; Vector (molecular biology); Genome editing; Cancer; Virology; Biology; Computer science; Recombinant DNA; Genetics; Gene","score_opus":0.009325946847151493,"score_gpt":0.32607592156674853,"score_spread":0.31674997471959704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396748464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96902406,0.0017655278,0.026466034,0.00012342453,0.0022660454,0.00019565911,0.000066075954,0.000057810234,0.00003534634],"genre_scores_gemma":[0.9967715,0.000040575695,0.0019651572,0.00007645169,0.00095718284,0.00008770435,0.000020573383,0.000026220985,0.000054625016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916977,0.000004590381,0.00013022682,0.0003234262,0.00010214444,0.00026982612],"domain_scores_gemma":[0.99971277,0.000005306186,0.000020247475,0.00017147494,0.0000444128,0.000045787165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000319925,0.00010268644,0.00008292192,0.000057540754,0.000085714884,0.00015879632,0.0002188334,0.000046591125,0.00001968311],"category_scores_gemma":[0.000017546254,0.00009083088,0.000049973427,0.00012214395,0.00011764695,0.0000057921757,0.000037071626,0.000009120864,0.000003999531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013007007,0.000004846329,0.000021766537,0.00004604288,0.0000068223085,6.7743827e-7,0.000026539348,0.0002462769,0.99844486,0.000020788704,0.00011444361,0.0010539603],"study_design_scores_gemma":[0.00013640392,0.00008984806,0.001188922,0.000023581788,0.0000041956882,0.0000021665032,0.0000075512703,0.0014190585,0.9684376,0.0000104597675,0.028556364,0.00012382623],"about_ca_topic_score_codex":0.00002279761,"about_ca_topic_score_gemma":0.0000034006875,"teacher_disagreement_score":0.030007206,"about_ca_system_score_codex":0.000022091666,"about_ca_system_score_gemma":0.00017483342,"threshold_uncertainty_score":0.37039757},"labels":[],"label_agreement":null},{"id":"W4396783453","doi":"10.2139/ssrn.4821731","title":"Swi4-Dependent Swi4 Transcription Couples Cell Size to Cell Cycle Commitment","year":2024,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hospital for Sick Children","funders":"","keywords":"Transcription (linguistics); Transcription factor; Cell biology; Biology; Genetics; Gene","score_opus":0.004591209566928329,"score_gpt":0.25902209701649076,"score_spread":0.25443088744956244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396783453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87712514,0.07215459,0.04553225,0.00079887797,0.0019234209,0.0006038033,0.00006706525,0.000053361142,0.0017414889],"genre_scores_gemma":[0.97344995,0.019641792,0.00040972393,0.00013028218,0.0010214162,0.000044700715,0.00006463683,0.00009756731,0.0051399306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688345,0.000056581994,0.00044211283,0.0006137047,0.00033171056,0.0016724631],"domain_scores_gemma":[0.99912524,0.000011989181,0.000107753534,0.00046462787,0.00008324502,0.00020715492],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007755604,0.00043770444,0.00030786166,0.00010173862,0.00010846909,0.00013721877,0.00049855903,0.00038264567,0.00003296643],"category_scores_gemma":[0.000015712028,0.0004363675,0.00036124338,0.000072292685,0.000020211042,0.000002214714,0.00039852023,0.002504435,0.0000643993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011335149,0.00018367943,0.000044243454,0.00024953956,0.0003167874,0.000014662861,0.00024492605,0.037290957,0.95398194,0.0002767455,0.001289586,0.0059935595],"study_design_scores_gemma":[0.0019447175,0.0020008453,0.00022076494,0.00024487797,0.00062481663,0.00040176345,0.0017519133,0.0009702424,0.91386807,0.03602161,0.04015307,0.0017972993],"about_ca_topic_score_codex":0.00006808395,"about_ca_topic_score_gemma":0.00056899386,"teacher_disagreement_score":0.0963248,"about_ca_system_score_codex":0.00048156123,"about_ca_system_score_gemma":0.0012814301,"threshold_uncertainty_score":0.9998088},"labels":[],"label_agreement":null},{"id":"W4396816546","doi":"10.1016/b978-0-443-21625-1.00027-0","title":"Genome editing as a promising tool to dissect the stress biology","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Agriculture and Agri-Food Canada","funders":"","keywords":"Biology; Computational biology; Genome editing; Genome; Genetics; Evolutionary biology; Gene","score_opus":0.007271865742487896,"score_gpt":0.27805082408577864,"score_spread":0.27077895834329074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396816546","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00853677,0.006767821,0.00017439178,0.00021465309,0.00092224224,0.0008266671,0.00013626786,0.00005088316,0.9823703],"genre_scores_gemma":[0.037016615,0.00010376941,0.00021108439,0.00026816977,0.0028685092,0.00008259512,0.00015908365,0.0001413131,0.9591489],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986034,0.0000123429845,0.00031274607,0.0006018117,0.000122012876,0.00034770672],"domain_scores_gemma":[0.99917394,0.000015618158,0.00006743615,0.0005920617,0.000054757325,0.00009616301],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017393027,0.00039195406,0.0002787223,0.00007237519,0.00009922775,0.00007421853,0.00035297713,0.00033135124,0.000056216057],"category_scores_gemma":[0.00003644826,0.00030017903,0.0002217811,0.000013926412,0.000058087524,8.292238e-7,0.0003777879,0.0003340719,0.0001384428],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030688956,0.000006590019,0.000006543339,0.00024780168,0.0004264078,0.000039851435,0.00038283807,0.000093655835,0.2555234,0.0027770107,0.00016605562,0.74029917],"study_design_scores_gemma":[0.000085585685,0.00016016306,0.000013405094,0.00022596316,0.00009173105,0.000043115517,0.000020607933,0.000005428786,0.010713844,0.0017354047,0.98649865,0.0004061176],"about_ca_topic_score_codex":9.121993e-7,"about_ca_topic_score_gemma":0.000026214837,"teacher_disagreement_score":0.9863326,"about_ca_system_score_codex":0.000033417444,"about_ca_system_score_gemma":0.00007181266,"threshold_uncertainty_score":0.99994504},"labels":[],"label_agreement":null},{"id":"W4396863440","doi":"10.1002/iub.2826","title":"Delivery of <scp>AKT1</scp> phospho‐forms to human cells reveals differential substrate selectivity","year":2024,"lang":"en","type":"article","venue":"IUBMB Life","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Phosphorylation; AKT1; HEK 293 cells; Biology; Kinase; Cell biology; Serine; Protein kinase B; Biochemistry; Gene","score_opus":0.007759281473004205,"score_gpt":0.2724062684388722,"score_spread":0.264646986965868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396863440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99169326,0.0012377572,0.0056061326,0.000018801897,0.00035077336,0.00016766641,0.000051134204,0.0000370027,0.0008374856],"genre_scores_gemma":[0.997992,0.000093568364,0.00016001984,0.000075362586,0.0003097521,0.00001702393,0.000041839103,0.00003381573,0.0012766683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989574,0.000019036195,0.00023823134,0.00034799022,0.00014259396,0.00029475646],"domain_scores_gemma":[0.999456,0.000022662829,0.000032106364,0.00026916707,0.00005457746,0.00016551933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012007063,0.0001796826,0.00019079229,0.00006033621,0.0000447151,0.000040519833,0.00016628674,0.0001368925,0.000021622976],"category_scores_gemma":[0.000040167728,0.00016896627,0.00012548211,0.00014456997,0.000029147297,0.0000039386405,0.00009736063,0.0001102194,0.000025769923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000068800337,0.00003516142,0.00066345173,0.000103188984,0.0000774031,0.0000041074973,0.00009847285,0.0003507284,0.9917837,0.000086485954,0.0063036736,0.00048676174],"study_design_scores_gemma":[0.00016266062,0.00019492442,0.010198209,0.000036924564,0.000030815132,0.000003622594,0.000038523474,0.00012566042,0.98134935,0.00004963109,0.0077112243,0.00009843031],"about_ca_topic_score_codex":0.00003825995,"about_ca_topic_score_gemma":0.00003383128,"teacher_disagreement_score":0.010434311,"about_ca_system_score_codex":0.000013230848,"about_ca_system_score_gemma":0.000058931106,"threshold_uncertainty_score":0.68902445},"labels":[],"label_agreement":null},{"id":"W4396916259","doi":"10.1007/s42994-024-00165-5","title":"C-terminal frameshift mutations generate viable knockout mutants with developmental defects for three essential protein kinases","year":2024,"lang":"en","type":"article","venue":"aBIOTECH","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; Huazhong Agricultural University; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Frameshift mutation; Mutant; Kinase; Genetics; Mutation; Terminal (telecommunication); Biology; Cell biology; Gene; Computer science","score_opus":0.006876329444440451,"score_gpt":0.27705575012836436,"score_spread":0.2701794206839239,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396916259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8235709,0.0006978064,0.17490229,0.0000464416,0.000115109324,0.0004353935,0.000049865896,0.000046421075,0.00013575025],"genre_scores_gemma":[0.98396736,0.000010469246,0.014805053,0.000025779187,0.00022563589,0.00015826854,0.0001705102,0.000039365957,0.0005975619],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918354,0.0000071223126,0.00012696072,0.000338513,0.00009206863,0.00025179837],"domain_scores_gemma":[0.9997405,0.000009364093,0.000017860806,0.00013664506,0.000038230493,0.00005743047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006140009,0.00016151194,0.00009803798,0.000048421345,0.00009895857,0.00007583434,0.000101706144,0.00013384584,0.000018852128],"category_scores_gemma":[0.000020626761,0.00014308815,0.00005675285,0.000099283054,0.000042751424,0.000005146111,0.000045180816,0.000083456005,0.000013365547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040062565,0.000025677484,0.000083586405,0.00010382257,0.00006767797,0.000032341803,0.000033304266,0.00046110395,0.99117106,0.00010018542,0.0003255226,0.007555673],"study_design_scores_gemma":[0.00028800708,0.0002456087,0.00025886623,0.00007454806,0.0000342176,0.00009793854,0.000030054623,0.0013606534,0.9879889,0.00011236177,0.009272446,0.00023640321],"about_ca_topic_score_codex":0.00001536249,"about_ca_topic_score_gemma":0.0001625456,"teacher_disagreement_score":0.16039644,"about_ca_system_score_codex":0.000016166372,"about_ca_system_score_gemma":0.0001844392,"threshold_uncertainty_score":0.5834966},"labels":[],"label_agreement":null},{"id":"W4396922010","doi":"10.1016/j.chom.2024.04.016","title":"Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans","year":2024,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Horizon 2020; Vilnius University; H. Lundbeck A/S; Horizon 2020 Framework Programme; Novo Nordisk Fonden; Novo Nordisk; Institut Pasteur; Lundbeckfonden; Eidgenössische Technische Hochschule Zürich; Agence Nationale de la Recherche; European Regional Development Fund; European Commission; Deutsche Forschungsgemeinschaft; Infrastructures en Biologie Santé et Agronomie; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Lietuvos Mokslo Taryba; Oxford Nanopore Technologies; Villum Fonden; University of Otago","keywords":"Plasmid; CRISPR; Biology; Horizontal gene transfer; Genetics; Gene; Ribonucleoprotein; Cas9; Klebsiella pneumoniae; Computational biology; RNA; Escherichia coli; Genome","score_opus":0.0055357405660833425,"score_gpt":0.2683810761212437,"score_spread":0.2628453355551603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396922010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9060046,0.051934943,0.033450875,0.00021875436,0.0020575689,0.00043260952,0.00008748171,0.000077349425,0.005735782],"genre_scores_gemma":[0.99355835,0.00094031595,0.0001005188,0.00009524003,0.00014758875,0.0000123460395,0.00009079113,0.000054496853,0.0050003314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989217,0.000023728317,0.00022135102,0.0004249962,0.000067763955,0.00034047465],"domain_scores_gemma":[0.9995845,0.000014283881,0.00002283034,0.00025392778,0.000033590462,0.00009088392],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036096,0.00021925589,0.00017742072,0.00007728392,0.000029734585,0.000081813276,0.00017310928,0.00018237524,0.00005110721],"category_scores_gemma":[0.000008899162,0.00022922778,0.00008095425,0.00013963615,0.00004615389,0.000004606376,0.000068680216,0.00016251988,0.000053944674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019279081,0.000022256007,0.00016221938,0.00020435189,0.000032645647,0.000024557778,0.00054424367,0.00043054367,0.9713806,0.0000054991897,0.026919903,0.00025389917],"study_design_scores_gemma":[0.00022976256,0.000088424786,0.00004761718,0.000095402786,0.00001612578,0.00001880242,0.0001940887,0.00077823404,0.6311408,7.1346494e-7,0.36719134,0.00019867464],"about_ca_topic_score_codex":0.00007752492,"about_ca_topic_score_gemma":0.000052459607,"teacher_disagreement_score":0.34027144,"about_ca_system_score_codex":0.00004090797,"about_ca_system_score_gemma":0.000041356223,"threshold_uncertainty_score":0.9347638},"labels":[],"label_agreement":null},{"id":"W4396982853","doi":"10.2139/ssrn.4831314","title":"Enzyme-Free Crispr/Cas12a Microrna Assay by Amplified Single Particle Analysis","year":2024,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; microRNA; Computational biology; Molecular biology; Genetics; Chemistry; Biology; Gene","score_opus":0.0068195358636413345,"score_gpt":0.27512108177211486,"score_spread":0.26830154590847355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396982853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6294226,0.12019682,0.24711624,0.0013008418,0.0008663099,0.00024206353,0.00014322968,0.000067069916,0.0006448118],"genre_scores_gemma":[0.98826104,0.005811717,0.00029801155,0.00009815732,0.0007679464,0.00001824589,0.0002116926,0.00008297587,0.004450196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964496,0.00010819128,0.00049349776,0.0006866562,0.0002847095,0.00197736],"domain_scores_gemma":[0.9986759,0.000017705659,0.00017024306,0.0008459328,0.00011091805,0.00017932357],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0011727568,0.0004219778,0.00042141875,0.00015213317,0.00010921346,0.00021780156,0.00074561173,0.0004394344,0.00003267621],"category_scores_gemma":[0.00011883176,0.000415592,0.00065503205,0.0002785761,0.000049410657,0.0000028236452,0.0008585583,0.0025474855,0.00002511489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007306047,0.00014852836,0.0003419333,0.00006391592,0.0059978324,0.0000127052135,0.000088934576,0.0058765155,0.9661306,0.00080512336,0.015157003,0.005303808],"study_design_scores_gemma":[0.0009939574,0.00063720933,0.00009638965,0.00006903252,0.0032774846,0.00033988804,0.0005346542,0.00195022,0.9062912,0.045474313,0.03901125,0.0013244279],"about_ca_topic_score_codex":0.000076516575,"about_ca_topic_score_gemma":0.00085370813,"teacher_disagreement_score":0.35883844,"about_ca_system_score_codex":0.00034056496,"about_ca_system_score_gemma":0.00090146274,"threshold_uncertainty_score":0.9998296},"labels":[],"label_agreement":null},{"id":"W4397042453","doi":"10.1016/j.molmed.2024.04.014","title":"CRISPR/Cas9 screening: unraveling cancer immunotherapy’s ‘Rosetta Stone’","year":2024,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Immunotherapy; Cas9; Computational biology; Genome editing; Cancer; Cancer immunotherapy; Biology; Gene; Genetics","score_opus":0.035829342111564896,"score_gpt":0.4307978710365217,"score_spread":0.39496852892495676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4397042453","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000026656022,0.9847749,0.013197101,0.0002074791,0.0008592117,0.00025980436,0.000043506785,0.00007131455,0.0005600692],"genre_scores_gemma":[0.00024266125,0.99472153,0.00081474066,0.00021156057,0.00084563444,0.00017442089,0.0006586373,0.00031850947,0.0020122859],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99721545,0.00011205118,0.0008169006,0.00094343896,0.00034847818,0.00056368805],"domain_scores_gemma":[0.9987779,0.00001809777,0.0001547766,0.0008601159,0.0000458452,0.00014321905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038881923,0.0007723292,0.0013872491,0.000681774,0.00003280828,0.000027198386,0.00051722664,0.00056706107,0.00012485124],"category_scores_gemma":[0.000052356005,0.0006190507,0.000489191,0.0007960225,0.00012657601,0.0000022140482,0.0001951823,0.0006907622,0.000010106041],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011171669,0.000022377022,0.0000023249768,0.0023363077,0.0004395262,0.00017726215,0.000076488235,0.00015467283,0.00635861,0.000025929428,0.0042796712,0.98611563],"study_design_scores_gemma":[0.0005347477,0.00015987424,0.000008033522,0.0087639475,0.00078802713,0.000084173145,0.000026258285,0.000066203545,0.0008344527,0.00000980858,0.98810357,0.00062092894],"about_ca_topic_score_codex":0.0001360865,"about_ca_topic_score_gemma":0.00005501481,"teacher_disagreement_score":0.98549473,"about_ca_system_score_codex":0.00006638332,"about_ca_system_score_gemma":0.00011854974,"threshold_uncertainty_score":0.9996261},"labels":[],"label_agreement":null},{"id":"W4398143392","doi":"10.3390/genes15050646","title":"Simultaneous Detection of Common Founder Mutations Using a Cost-Effective Deep Sequencing Panel","year":2024,"lang":"en","type":"article","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Health, State of Israel; Israel Science Foundation; Foundation Fighting Blindness","keywords":"Genetics; DNA sequencing; Biology; Amplicon; Mutation; Mendelian inheritance; Deep sequencing; Founder effect; Sanger sequencing; Gene; Genotype; Polymerase chain reaction; Genome; Haplotype","score_opus":0.021415304265424512,"score_gpt":0.3249126198553258,"score_spread":0.30349731558990134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398143392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6976917,0.0036935557,0.29811874,0.000004027199,0.00019818114,0.00021898371,0.0000064741957,0.000018220951,0.00005012204],"genre_scores_gemma":[0.9987386,0.000064049986,0.00094155554,0.000011453288,0.00013687396,0.00003318334,0.00002092207,0.000018872286,0.000034491957],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952424,0.00002102803,0.00011370193,0.00016688467,0.000057309964,0.00011685891],"domain_scores_gemma":[0.9997502,0.000040577223,0.000019107783,0.00011840694,0.000043889555,0.00002781831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057993373,0.00008733082,0.00008088326,0.000046564175,0.000045974553,0.000017578976,0.000044045006,0.000071114184,0.0000037834704],"category_scores_gemma":[0.00003025145,0.00008874914,0.00005803763,0.000094632305,0.00002817002,0.0000023819323,0.00002794688,0.00004478695,0.0000024331864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006157706,0.0000051266743,0.000047497284,0.00004910524,0.00004020936,0.0000057660295,0.00012127294,0.14105089,0.7993365,0.000005129791,8.725311e-7,0.059331454],"study_design_scores_gemma":[0.00007988496,0.00007311536,0.00011781156,0.000020759931,0.00003971164,0.00006292208,0.00019250979,0.15835157,0.8394531,0.000055843942,0.0014543639,0.00009838714],"about_ca_topic_score_codex":0.00005949651,"about_ca_topic_score_gemma":0.00015793953,"teacher_disagreement_score":0.3010469,"about_ca_system_score_codex":0.000033199613,"about_ca_system_score_gemma":0.000029420436,"threshold_uncertainty_score":0.3619085},"labels":[],"label_agreement":null},{"id":"W4398193896","doi":"10.1016/j.jcyt.2024.03.047","title":"THERAPEUTIC GENOME EDITING FOR SEVERE MONOGENIC SKIN DISORDERS","year":2024,"lang":"en","type":"article","venue":"Cytotherapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Genome editing; Genetics; Biology; Medicine; Computational biology; Genome; Gene","score_opus":0.006766900999812881,"score_gpt":0.29335801324197525,"score_spread":0.2865911122421624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398193896","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40892228,0.055619687,0.53160745,0.0007042209,0.0011007717,0.00069914514,0.00007057315,0.00013441373,0.0011414569],"genre_scores_gemma":[0.9951066,0.0012044604,0.0011021899,0.0002543031,0.0010182676,0.000083646715,0.00006519004,0.000062726125,0.0011026625],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99934053,0.000009214795,0.00010963823,0.0002696559,0.000053161646,0.00021777634],"domain_scores_gemma":[0.999738,0.000013793303,0.000012415665,0.00018196911,0.00001477927,0.00003904995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000085198095,0.00013005831,0.00008431605,0.000035123656,0.000050570827,0.000040761868,0.00011219311,0.00008567279,0.000040555213],"category_scores_gemma":[0.0000048529837,0.00012337232,0.00013486647,0.00006290888,0.000020660382,0.0000023052576,0.0000146568145,0.000050213177,0.000009731681],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003291246,0.000018495844,0.00012178471,0.00006660071,0.0001809517,7.3737004e-7,0.00021377616,0.0013236871,0.9154842,0.00022816555,0.0009831911,0.08134548],"study_design_scores_gemma":[0.00061414216,0.00030632538,0.00092176924,0.000019240983,0.000026366475,0.000017337974,0.00011710881,0.002431989,0.14243397,0.0010034264,0.85173887,0.00036947272],"about_ca_topic_score_codex":0.0000027654805,"about_ca_topic_score_gemma":0.000013324395,"teacher_disagreement_score":0.85075563,"about_ca_system_score_codex":0.000010569675,"about_ca_system_score_gemma":0.000027228067,"threshold_uncertainty_score":0.5030977},"labels":[],"label_agreement":null},{"id":"W4399087850","doi":"10.1038/s41587-024-02266-4","title":"Enhancing prime editing in hematopoietic stem and progenitor cells by modulating nucleotide metabolism","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Harvard Stem Cell Institute; Broad Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American-Italian Cancer Foundation; St. Jude Children's Research Hospital; Fred Hutchinson Cancer Research Center; Doris Duke Charitable Foundation; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Progenitor cell; Haematopoiesis; Stem cell; Nucleotide; Cell biology; Prime (order theory); Biology; Metabolism; Progenitor; Biochemistry; Gene","score_opus":0.0021585488030811586,"score_gpt":0.24446539052301913,"score_spread":0.24230684171993797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399087850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9467737,0.04569368,0.00591726,0.0005629834,0.00065724534,0.00020336267,0.000013322337,0.0001277848,0.000050675062],"genre_scores_gemma":[0.9965664,0.00032320438,0.0025558008,0.000055020755,0.00028748775,0.000016950677,0.000013758835,0.00003834454,0.00014301558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888563,0.00001821666,0.00021854711,0.00048441836,0.000084234496,0.00030894706],"domain_scores_gemma":[0.99966705,0.000015842697,0.000031134314,0.00022523593,0.000017226888,0.000043514654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016475456,0.00018234564,0.00017953721,0.0001338513,0.000038013462,0.000034432796,0.00013733462,0.00093223614,0.000003240249],"category_scores_gemma":[0.00003616026,0.00017996324,0.000045339544,0.00020003981,0.00005551889,0.000004613992,0.00015242897,0.000599389,0.0000037827324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034395127,0.000009135695,0.00005183288,0.000083342464,0.000023069488,0.000011240854,0.00004903961,0.000021192862,0.9917579,0.00030598586,0.00028208038,0.0074017197],"study_design_scores_gemma":[0.00013977289,0.000035857218,0.000046644473,0.0000656275,0.000013289301,0.000043556534,0.0001288981,0.0007512096,0.97239417,0.000051331826,0.026156045,0.00017357939],"about_ca_topic_score_codex":0.000006141641,"about_ca_topic_score_gemma":0.000016620566,"teacher_disagreement_score":0.04979273,"about_ca_system_score_codex":0.000014444701,"about_ca_system_score_gemma":0.00002280384,"threshold_uncertainty_score":0.73386884},"labels":[],"label_agreement":null},{"id":"W4399097662","doi":"10.1111/pbi.14375","title":"Multiplex‐genome‐editing based rapid directional improvement of complex traits in rice","year":2024,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Fujian Academy of Agricultural Sciences; South China Agricultural University; Natural Science Foundation of Fujian Province; Directorate for Biological Sciences; Chinese Academy of Agricultural Sciences; China Agricultural University","keywords":"Biology; Germplasm; Genome; Oryza sativa; Computational biology; Genetics; Gene; Biotechnology; Agronomy","score_opus":0.01065031471531729,"score_gpt":0.2593219450988699,"score_spread":0.2486716303835526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399097662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9210312,0.0066416585,0.06990576,0.0012307604,0.0005580075,0.00016327524,0.000186552,0.000057299872,0.00022551272],"genre_scores_gemma":[0.99613845,0.0004493637,0.0030417214,0.000048730606,0.00021363435,0.0000061944024,0.00006565328,0.00001417751,0.000022086317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999154,0.000015195274,0.0002938725,0.0002057997,0.000100452104,0.00023072145],"domain_scores_gemma":[0.99976355,0.000021232947,0.000055608434,0.000091771406,0.000025602445,0.000042234937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024763943,0.000121461635,0.00013960563,0.00026009703,0.000043478172,0.000015902968,0.0001521713,0.00022417524,0.00004125342],"category_scores_gemma":[0.000050896444,0.000113824426,0.00007604291,0.0001533573,0.00005844904,0.0000027085155,0.000044754845,0.0003155096,0.0000021529033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002443972,0.000037150166,0.000144477,0.000044998927,0.000048555008,0.000030289926,0.000017848708,0.000977256,0.97860456,0.00002696532,0.00022382541,0.019819638],"study_design_scores_gemma":[0.00056834,0.00032093955,0.005126717,0.00006779873,0.000015243203,0.000471991,0.00009094231,0.0065677934,0.9399109,0.000030375519,0.04666734,0.00016163182],"about_ca_topic_score_codex":0.0000071530617,"about_ca_topic_score_gemma":0.00002593881,"teacher_disagreement_score":0.07510726,"about_ca_system_score_codex":0.000024387047,"about_ca_system_score_gemma":0.00005750388,"threshold_uncertainty_score":0.46416253},"labels":[],"label_agreement":null},{"id":"W4399158777","doi":"10.1186/s12967-024-05235-2","title":"CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy","year":2024,"lang":"en","type":"review","venue":"Journal of Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universidade de Macau; Basic and Applied Basic Research Foundation of Guangdong Province; University of Toronto","keywords":"CRISPR; Computational biology; Precision medicine; Genome editing; Cancer; Drug discovery; Genetic enhancement; Guide RNA; Bioinformatics; Medicine; Biology; Gene; Genetics","score_opus":0.04372693328924527,"score_gpt":0.40459617100268513,"score_spread":0.36086923771343987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399158777","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000107039865,0.889514,0.108926736,0.00039321822,0.0006108679,0.00033259767,0.0001010503,0.0000056551144,0.000008776305],"genre_scores_gemma":[0.0032893857,0.9875763,0.0051472895,0.000039028935,0.0037143568,0.00003641203,0.00011349732,0.000055191147,0.000028516124],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986611,0.000040294963,0.00067298615,0.00023795986,0.00022995322,0.00015770126],"domain_scores_gemma":[0.99923885,0.00010043989,0.0002720045,0.00009124509,0.00017430959,0.00012313775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047250345,0.00027727935,0.00076173095,0.00018026542,0.000055318655,0.000019802123,0.00009750922,0.0001985091,0.0000070654582],"category_scores_gemma":[0.000053763375,0.00019042988,0.00021537708,0.00008761303,0.000053996057,0.000004630653,0.000010272,0.00021867038,1.0294021e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016351206,0.00001858189,0.00003167919,0.017939944,0.0010328743,0.000021621985,0.00012861055,0.00051980105,0.006290932,0.000017618484,0.0025030235,0.9713318],"study_design_scores_gemma":[0.0020969068,0.00058380445,0.00004915953,0.019114109,0.0020361284,0.00041756177,0.000057028636,0.000954092,0.002601649,0.000017592532,0.97175074,0.00032121403],"about_ca_topic_score_codex":0.0000050477706,"about_ca_topic_score_gemma":0.0000035948437,"teacher_disagreement_score":0.97101057,"about_ca_system_score_codex":0.000015143137,"about_ca_system_score_gemma":0.00015806146,"threshold_uncertainty_score":0.77655053},"labels":[],"label_agreement":null},{"id":"W4399285409","doi":"10.7554/elife.91288.3","title":"Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Terry Fox Research Institute; Cancer Research Society","keywords":"Genome editing; Progenitor cell; Stem cell; Biology; Haematopoiesis; Computational biology; CRISPR; Cord blood; Primary cell; Genetics; Cell; Gene","score_opus":0.007287696831792061,"score_gpt":0.28505152797940037,"score_spread":0.27776383114760833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399285409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994757,0.0037026177,0.000661124,0.000023510263,0.00029413015,0.00012501373,0.000013613791,0.000022827877,0.0004001404],"genre_scores_gemma":[0.99863166,0.00004469459,0.0004409365,0.000019712395,0.00047117192,0.000012389258,0.000011073667,0.00002298702,0.00034538383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993916,0.000013748623,0.00014054353,0.0002162514,0.00010307015,0.00013474232],"domain_scores_gemma":[0.9997319,0.00001176642,0.000018445182,0.00015927624,0.000022812974,0.00005581497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110124,0.00010281918,0.00010422516,0.000022950908,0.00004002899,0.00003068491,0.000062903775,0.0000668057,0.000011290173],"category_scores_gemma":[0.00000982212,0.00009511568,0.000051272622,0.000043911106,0.000034659315,0.0000015242333,0.00004890765,0.00006439269,0.000007890493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006117438,0.000017861923,0.00042147315,0.00020643637,0.000034843197,0.0000048096576,0.00018987364,0.0002548134,0.9957338,0.00003675163,0.0021073492,0.0009858866],"study_design_scores_gemma":[0.00010676698,0.0002036372,0.00012536575,0.00007306116,0.000012405197,0.000008256107,0.000058147467,0.0005053086,0.98981404,0.0000057117677,0.008989619,0.0000976705],"about_ca_topic_score_codex":0.0000021121707,"about_ca_topic_score_gemma":0.0000010387755,"teacher_disagreement_score":0.0068822694,"about_ca_system_score_codex":0.0000040593422,"about_ca_system_score_gemma":0.000021699634,"threshold_uncertainty_score":0.3878705},"labels":[],"label_agreement":null},{"id":"W4399418835","doi":"10.1038/s41598-024-62996-y","title":"An efficient low cost means of biophysical gene transfection in primary cells","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Princess Margaret Cancer Centre; University of Toronto; University Health Network; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Vanderbilt University","keywords":"Transfection; Gene; Primary cell; Computational biology; Primary (astronomy); Biology; Bioinformatics; Cell biology; Genetics","score_opus":0.003953363634698659,"score_gpt":0.25728853246322003,"score_spread":0.25333516882852136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399418835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747792,0.00030880555,0.021198194,0.000008666689,0.0032958926,0.00018096536,0.000004905178,0.000017085331,0.00020629817],"genre_scores_gemma":[0.9992654,0.000012279357,0.00031628922,0.0000044825288,0.0000811165,0.000011051661,0.00010352764,0.000012834545,0.00019305536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893516,0.000017476246,0.00024436458,0.0004782908,0.00016667362,0.00015800679],"domain_scores_gemma":[0.9995021,0.0000036924348,0.000023257913,0.00037927387,0.000035015797,0.00005663561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040522846,0.000087684,0.000097624594,0.00009765025,0.000029087241,0.000047780148,0.00006098902,0.00006268065,0.00001016351],"category_scores_gemma":[0.0000065148033,0.00008352659,0.00007482773,0.0002536268,0.00007957317,0.0000030299593,0.000017764087,0.00005430816,0.0000027084877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000056609274,0.00008859033,0.000097396914,0.00006708766,0.000006328063,0.000048024205,0.00009489361,0.039129358,0.9578691,0.000004545741,0.00025384614,0.0023351307],"study_design_scores_gemma":[0.0000574661,0.000047508736,0.0008788977,0.000029691057,0.000008182832,0.000039267416,0.000013663527,0.0077474792,0.9878167,0.000020013746,0.0032467789,0.00009433983],"about_ca_topic_score_codex":0.0000093985855,"about_ca_topic_score_gemma":0.000012684201,"teacher_disagreement_score":0.03138188,"about_ca_system_score_codex":0.00001807858,"about_ca_system_score_gemma":0.00007874913,"threshold_uncertainty_score":0.34061155},"labels":[],"label_agreement":null},{"id":"W4399427909","doi":"10.1038/s41467-024-49198-w","title":"Protein translation rate determines neocortical neuron fate","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Russian Science Foundation; Fritz Thyssen Stiftung; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft","keywords":"Translation (biology); Neuron; Neocortex; Neuroscience; Computer science; Biology; Biochemistry","score_opus":0.01537101672041536,"score_gpt":0.33812976943759915,"score_spread":0.3227587527171838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399427909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83989155,0.09697233,0.04325237,0.01142835,0.0007443436,0.001058007,0.00005845151,0.00029671917,0.0062978733],"genre_scores_gemma":[0.9948707,0.0004660854,0.00396521,0.00010389652,0.00010690075,0.000053825835,0.00013855145,0.000018816354,0.00027601453],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995304,0.00004681734,0.00011403483,0.00015678635,0.00004743129,0.00010456714],"domain_scores_gemma":[0.999238,0.000025201245,0.0000102831045,0.0006595861,0.000031254593,0.00003568601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008555192,0.00008427856,0.000053073632,0.000035590743,0.00006449913,0.000040923635,0.00028108832,0.00016418057,0.0000053916365],"category_scores_gemma":[0.00004709947,0.00008009594,0.000056011686,0.00010925348,0.000039429688,0.000003710863,0.00007806671,0.00029107445,0.000010995654],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006444887,0.000016621345,0.00005869089,0.000019707622,0.000017030452,0.0000012327866,0.00003468865,0.000070324364,0.9818844,0.0010993346,0.0005712721,0.016220259],"study_design_scores_gemma":[0.000185307,0.00009119607,0.0036713604,0.000052416337,0.000040622963,0.000017397435,0.000015873042,0.019066557,0.25415,0.00021541303,0.7222388,0.00025504208],"about_ca_topic_score_codex":0.0000020291357,"about_ca_topic_score_gemma":0.00006992003,"teacher_disagreement_score":0.7277344,"about_ca_system_score_codex":0.000004644959,"about_ca_system_score_gemma":0.000026400257,"threshold_uncertainty_score":0.32662174},"labels":[],"label_agreement":null},{"id":"W4399427988","doi":"10.1016/j.talanta.2024.126379","title":"CRISPR-Hg: Rapid and visual detection of Hg2+ based on PCR coupled with CRISPR/Cas12a","year":2024,"lang":"en","type":"article","venue":"Talanta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Education and Child Care","funders":"Agriculture Research System of China; Jilin Province Development and Reform Commission","keywords":"Chemistry; CRISPR; Computational biology; Biochemistry; Gene","score_opus":0.004990033603576034,"score_gpt":0.2724432883616216,"score_spread":0.2674532547580456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399427988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9677846,0.0013522144,0.030084867,0.000042351567,0.00011406312,0.00011514439,0.000013342142,0.000028375513,0.00046503788],"genre_scores_gemma":[0.99943346,0.00013927273,0.00007754263,0.000050990515,0.00010849435,0.000008276719,0.000033626795,0.000023904313,0.00012446105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994016,0.000012965312,0.000108576125,0.00024350172,0.00009826448,0.00013507588],"domain_scores_gemma":[0.9997524,0.000016422178,0.00001882755,0.00013833732,0.000024329342,0.00004968446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007715787,0.00012330995,0.00010727841,0.00005987894,0.000026833863,0.000019865964,0.00004329282,0.000076983204,0.000019148329],"category_scores_gemma":[0.0000132385085,0.000102707985,0.00003782832,0.00007897507,0.00003787909,0.00000209387,0.000022824963,0.00007098366,0.0000037600093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015924372,0.000028108838,0.00028614097,0.00012439475,0.000037974543,0.000011008446,0.000026115591,0.00049366185,0.99350023,0.00000782249,0.00017310787,0.005152176],"study_design_scores_gemma":[0.00043188012,0.0009950377,0.002346135,0.00006566111,0.00004031057,0.0000344895,0.00004748212,0.0405153,0.95134485,0.0000035100234,0.0040153167,0.00016000352],"about_ca_topic_score_codex":0.000020483818,"about_ca_topic_score_gemma":0.00002405119,"teacher_disagreement_score":0.042155374,"about_ca_system_score_codex":0.0000060188327,"about_ca_system_score_gemma":0.000027128182,"threshold_uncertainty_score":0.418831},"labels":[],"label_agreement":null},{"id":"W4399504457","doi":"10.1158/1538-8514.synthleth24-b025","title":"Abstract B025: A genome-wide CRISPR screen identifies synthetic lethality of double-stranded RNA with BRCA1 loss","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"RNA silencing; Biology; Interferon; RNA; Programmed cell death; CRISPR; Cell biology; RNA interference; Molecular biology; Genetics; Gene; Apoptosis","score_opus":0.01680530824172085,"score_gpt":0.31105312946064945,"score_spread":0.2942478212189286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399504457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89458895,0.025482012,0.07800917,0.00042067547,0.0002235062,0.00031860932,0.000091721806,0.000049896084,0.0008154307],"genre_scores_gemma":[0.99759984,0.0013726527,0.00031264886,0.00022507586,0.0001021985,0.000040811374,0.00005337738,0.00007494641,0.00021846092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985731,0.000027789458,0.00030674852,0.00047291417,0.00027952043,0.00033987706],"domain_scores_gemma":[0.9991978,0.000017330673,0.000062613195,0.0005295708,0.00010942055,0.00008330455],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001804734,0.00028414867,0.0002497009,0.00007434063,0.000047669273,0.000070760565,0.0002746725,0.00016241454,0.000056538847],"category_scores_gemma":[0.000004435285,0.00025209156,0.00017667659,0.00017718575,0.00015873004,0.0000066087323,0.000060359238,0.00017966735,0.0000049308933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002094992,0.0000461109,0.00042167614,0.00030861347,0.00073029415,0.00006178933,0.00018589925,0.0046559838,0.9895017,0.00008777276,0.000029407924,0.0037612324],"study_design_scores_gemma":[0.0007204234,0.00013214507,0.0033496793,0.00013824108,0.00022285985,0.000019422023,0.00006567714,0.00011185547,0.97980475,0.00011384232,0.014963438,0.00035766046],"about_ca_topic_score_codex":0.00013253572,"about_ca_topic_score_gemma":0.00010935879,"teacher_disagreement_score":0.103010856,"about_ca_system_score_codex":0.000029559877,"about_ca_system_score_gemma":0.0001459071,"threshold_uncertainty_score":0.99999315},"labels":[],"label_agreement":null},{"id":"W4399504527","doi":"10.1158/1538-8514.synthleth24-pr014","title":"Abstract PR014: Combinatorial genetic screens to map synthetic lethal interactions and identify new cancer drug targets in <i>KRAS</i> mutant cancers","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Computational biology; Cas9; Biology; Gene; Synthetic lethality; Genetics; Precision medicine; Personalized medicine; KRAS; Drug discovery; Genetic screen; Mutant; Mutation; Bioinformatics","score_opus":0.011146393027114728,"score_gpt":0.32737120774996303,"score_spread":0.3162248147228483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399504527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91931295,0.060848042,0.013466005,0.0021910793,0.0033297043,0.0005423056,0.00010205252,0.00005297858,0.00015487985],"genre_scores_gemma":[0.995402,0.0024594592,0.00045050934,0.0006962895,0.00048591255,0.00013036474,0.000018629024,0.000085951695,0.00027088297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984122,0.00003602947,0.0003028057,0.0005999604,0.00021366386,0.00043537654],"domain_scores_gemma":[0.9993735,0.000017752543,0.000038587426,0.00032298794,0.000050380146,0.00019679846],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000103752296,0.00030619834,0.00022257463,0.00012968127,0.000057275618,0.000114830844,0.00020742396,0.00012190464,0.0000726045],"category_scores_gemma":[0.00000811058,0.00032341052,0.00010504804,0.0002070594,0.0000537012,0.0000085409365,0.00010569942,0.0002660613,0.000009627252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006739421,0.000029035302,0.00039659845,0.00011817708,0.00024994533,0.000083781546,0.00062100583,0.012492874,0.9650127,0.000061029827,0.0010527986,0.019814637],"study_design_scores_gemma":[0.0009299931,0.00011775263,0.0049041123,0.00045168266,0.00020178298,0.00003521961,0.00019623114,0.0016538813,0.76679957,0.00032775174,0.22358336,0.0007986755],"about_ca_topic_score_codex":0.002046675,"about_ca_topic_score_gemma":0.0022205296,"teacher_disagreement_score":0.22253056,"about_ca_system_score_codex":0.00016952465,"about_ca_system_score_gemma":0.00034252275,"threshold_uncertainty_score":0.9999218},"labels":[],"label_agreement":null},{"id":"W4399504696","doi":"10.1158/1538-8514.synthleth24-ia020","title":"Abstract IA020: Functional studies of genetic variation using precision genome editing","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biology; Genome editing; Genome; Computational biology; Genetics; Indel; Gene; Precision medicine; Genotype; Single-nucleotide polymorphism","score_opus":0.03605868568233169,"score_gpt":0.3466691388137472,"score_spread":0.31061045313141555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399504696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68813646,0.0705432,0.24034387,0.000058315778,0.00071412855,0.00011836935,0.0000212174,0.000018465367,0.00004598582],"genre_scores_gemma":[0.9945715,0.0016872754,0.0030248936,0.00010119748,0.0005002682,0.000015355703,0.000022443764,0.00003964396,0.0000373999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909973,0.000019857807,0.00024850856,0.00027365203,0.00018690393,0.00017136212],"domain_scores_gemma":[0.9995916,0.000013992594,0.00005336081,0.00019358477,0.00011654929,0.00003089405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012454175,0.00014898436,0.0001302363,0.00006376293,0.00004400335,0.000023954315,0.000086087704,0.000097282005,0.000024156043],"category_scores_gemma":[0.000012764695,0.0001459762,0.00010182046,0.00012674977,0.000040663454,0.000003865497,0.000053764332,0.00008277216,0.000001687459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014939498,0.000012286937,0.00011733762,0.00011363708,0.0003511789,0.000005084742,0.00015780293,0.068793364,0.9220783,0.00002751822,0.000019083196,0.008309456],"study_design_scores_gemma":[0.0003928179,0.00015250538,0.017391948,0.00021047481,0.00031086133,0.00002586169,0.00016391477,0.01569808,0.9500707,0.0004291196,0.0147443535,0.00040940495],"about_ca_topic_score_codex":0.000012422004,"about_ca_topic_score_gemma":0.0000047397957,"teacher_disagreement_score":0.30643508,"about_ca_system_score_codex":0.000042009124,"about_ca_system_score_gemma":0.00008219209,"threshold_uncertainty_score":0.5952737},"labels":[],"label_agreement":null},{"id":"W4399505200","doi":"10.1158/1538-8514.synthleth24-b012","title":"Abstract B012: Predicting targetable paralog synthetic lethalities and functional redundancies in cancer genomes","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Concordia University","funders":"","keywords":"Synthetic lethality; Biology; Breast cancer; Cancer; Genome; Gene; Cancer cell; Genetics; Context (archaeology); Computational biology; Triple-negative breast cancer; Gene duplication; CRISPR; Cancer research; DNA repair","score_opus":0.019180244438083548,"score_gpt":0.3024860092635994,"score_spread":0.2833057648255159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399505200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7411842,0.25449073,0.0029262505,0.00040562588,0.00046353476,0.0001285671,0.000046722966,0.000031526848,0.00032286285],"genre_scores_gemma":[0.9892583,0.009392525,0.00017389125,0.00030851763,0.0002137202,0.000106587504,0.000025300604,0.000044974622,0.0004762032],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900305,0.000020662304,0.0001880375,0.0003534407,0.00013603336,0.0002987803],"domain_scores_gemma":[0.99971133,0.000015556625,0.000023833963,0.00016790944,0.000031582204,0.00004979116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012719588,0.00018814916,0.000140645,0.00006888495,0.00005209594,0.00006961398,0.000076348595,0.00011717439,0.000060324495],"category_scores_gemma":[0.000005674477,0.00018593813,0.00006407019,0.00010709081,0.00007911694,0.0000068434815,0.00004966677,0.000152483,0.0000017095706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032035092,0.000021188604,0.00648297,0.0002220078,0.00023450707,0.000020669795,0.0003648072,0.019094257,0.9590091,0.00016275414,0.000112872054,0.0142427925],"study_design_scores_gemma":[0.000614682,0.00012471991,0.025729492,0.0003655003,0.00016908589,0.000041924213,0.00044211978,0.006536844,0.8051897,0.00069360976,0.15931292,0.0007793692],"about_ca_topic_score_codex":0.00017718326,"about_ca_topic_score_gemma":0.00015742071,"teacher_disagreement_score":0.24807411,"about_ca_system_score_codex":0.000043191358,"about_ca_system_score_gemma":0.0001243031,"threshold_uncertainty_score":0.7582337},"labels":[],"label_agreement":null},{"id":"W4399533105","doi":"10.3390/ph17060763","title":"Emerging Perspectives on Prime Editor Delivery to the Brain","year":2024,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal; Université Laval","funders":"","keywords":"Nanomedicine; CRISPR; Prime (order theory); Cas9; Genome editing; Computer science; Medicine; Engineering ethics; Computational biology; Neuroscience; Nanotechnology; Bioinformatics; Psychology; Biology; Engineering","score_opus":0.014658199219230091,"score_gpt":0.38779951272899765,"score_spread":0.37314131350976754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399533105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7572251,0.060741764,0.08648632,0.071309984,0.013619937,0.0013578421,0.00009686656,0.00033224633,0.008829951],"genre_scores_gemma":[0.9910012,0.0003227582,0.00020124918,0.0015171242,0.0059846146,0.000029930963,0.000006047194,0.000024356441,0.0009127138],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992645,0.000030085506,0.000092132366,0.00028487752,0.00011776448,0.00021063561],"domain_scores_gemma":[0.9996267,0.00005101002,0.000005517602,0.00019453063,0.000026094029,0.00009612857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020753959,0.00010980677,0.000062896404,0.00003679638,0.00005527819,0.00004745958,0.00014603416,0.000042071984,0.0000767134],"category_scores_gemma":[0.00009913162,0.0000803892,0.00007003936,0.00010130162,0.000024581866,0.0000017492288,0.00008077334,0.00012013463,0.00016296838],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003656598,0.000028324841,0.000016160671,0.00002121039,0.00008447245,0.000005956637,0.00070742273,0.0010768307,0.8113902,0.0003659964,0.16343506,0.022831805],"study_design_scores_gemma":[0.000067225046,0.00005666051,0.000054109783,0.0000148714,0.000013171755,0.0000040324735,0.00022779708,0.0011831252,0.28987607,0.000008928093,0.7083974,0.00009658248],"about_ca_topic_score_codex":0.0000016191059,"about_ca_topic_score_gemma":0.0000011235519,"teacher_disagreement_score":0.54496235,"about_ca_system_score_codex":0.000013757688,"about_ca_system_score_gemma":0.000023685618,"threshold_uncertainty_score":0.32781765},"labels":[],"label_agreement":null},{"id":"W4399555205","doi":"10.1016/j.omtn.2024.102248","title":"Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Minicircle; Cytosine; CRISPR; Cytosine deaminase; DNA; Gene delivery; Biology; Enhancer; Computational biology; Reporter gene; Cas9; Thymine; Plasmid; Gene; Genetic enhancement; Genetics","score_opus":0.019423394366986008,"score_gpt":0.311431732164499,"score_spread":0.292008337797513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399555205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9470504,0.01239557,0.039526735,0.000033174932,0.0005433784,0.00037241788,0.00003515229,0.000011555908,0.000031598374],"genre_scores_gemma":[0.9978683,0.00014834333,0.0014143019,0.000026409207,0.00040586138,0.000024717221,0.000049106045,0.000046799447,0.000016151156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988986,0.0000549222,0.00029017212,0.00031655273,0.0002842599,0.00015548876],"domain_scores_gemma":[0.99934876,0.000017467244,0.000083167106,0.00029849674,0.00021140542,0.00004073282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005771129,0.00015405974,0.00018679033,0.00009153412,0.000029541206,0.000022570268,0.000077796976,0.00008501092,0.0000059541658],"category_scores_gemma":[0.000045220644,0.00014956675,0.00009942672,0.00008822877,0.000038708018,0.0000057698344,0.000032126376,0.000041451098,2.147532e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007952006,0.00003188639,0.00009772458,0.000097470474,0.00017385939,0.00000445266,0.00004993755,0.00618938,0.98361725,0.000008821097,0.00017264429,0.009477077],"study_design_scores_gemma":[0.000641859,0.00021235124,0.000159873,0.00011412217,0.00012490936,0.000029003175,0.00005898588,0.062155794,0.93434924,0.000019635892,0.0019896885,0.00014452264],"about_ca_topic_score_codex":0.000018938936,"about_ca_topic_score_gemma":5.697461e-7,"teacher_disagreement_score":0.055966415,"about_ca_system_score_codex":0.000023372224,"about_ca_system_score_gemma":0.00007881457,"threshold_uncertainty_score":0.6099155},"labels":[],"label_agreement":null},{"id":"W4399602980","doi":"10.32920/26015170","title":"Control of GSK3β nuclear localization by amino acid signaling requires GATOR1 but is mTORC1-independent","year":2024,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Dalhousie University; Toronto Metropolitan University","funders":"","keywords":"mTORC1; Amino acid; Cytosol; Lysosome; Cell biology; Biology; Biochemistry; Nuclear localization sequence; Nuclear export signal; Cytoplasm; Cell growth; Signal transduction; Cell nucleus; Enzyme; PI3K/AKT/mTOR pathway","score_opus":0.006001885117882452,"score_gpt":0.2642211160578483,"score_spread":0.25821923093996585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399602980","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3183734,0.017890502,0.6582992,0.00026996539,0.0011825849,0.0007549749,0.0006515475,0.0001225446,0.0024552913],"genre_scores_gemma":[0.9975245,0.00031647048,0.00038621033,0.00028231344,0.0002814627,0.00001918807,0.00025710237,0.000073555915,0.0008592242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984695,0.000031244363,0.00042637557,0.00058964733,0.00024350153,0.00023974448],"domain_scores_gemma":[0.999184,0.000007381864,0.0001137268,0.00048718276,0.000112585716,0.00009511324],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015320799,0.00030359975,0.00031055885,0.000063966545,0.00003234208,0.00005365013,0.000269557,0.00051896396,0.00019414733],"category_scores_gemma":[0.00003132425,0.00030076798,0.00021629698,0.000048060414,0.0000501952,0.0000013699765,0.0005011794,0.00024753218,0.000019753392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036244193,0.000030704723,0.000066970744,0.0003964843,0.00024044006,0.0000032356595,0.000087902794,0.007099497,0.97989756,0.00017092541,0.011435648,0.00053441216],"study_design_scores_gemma":[0.00035749262,0.00011334197,0.000008218661,0.00012378195,0.00012543258,0.000005479774,0.00010244054,0.008709944,0.97378254,0.00031759727,0.015995305,0.00035844318],"about_ca_topic_score_codex":0.000092769114,"about_ca_topic_score_gemma":0.0000065484714,"teacher_disagreement_score":0.67915106,"about_ca_system_score_codex":0.000026708334,"about_ca_system_score_gemma":0.00007602246,"threshold_uncertainty_score":0.99994445},"labels":[],"label_agreement":null},{"id":"W4399624100","doi":"10.32920/26015170.v1","title":"Control of GSK3β nuclear localization by amino acid signaling requires GATOR1 but is mTORC1-independent","year":2024,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Dalhousie University; Toronto Metropolitan University","funders":"","keywords":"mTORC1; Amino acid; Cytosol; Lysosome; Cell biology; Biology; Cytoplasm; Biochemistry; Nuclear localization sequence; Nuclear export signal; Cell growth; Nuclear transport; Signal transduction; Cell nucleus; Enzyme; Protein kinase B","score_opus":0.006001885117882452,"score_gpt":0.2642211160578483,"score_spread":0.25821923093996585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399624100","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3183734,0.017890502,0.6582992,0.00026996539,0.0011825849,0.0007549749,0.0006515475,0.0001225446,0.0024552913],"genre_scores_gemma":[0.9975245,0.00031647048,0.00038621033,0.00028231344,0.0002814627,0.00001918807,0.00025710237,0.000073555915,0.0008592242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984695,0.000031244363,0.00042637557,0.00058964733,0.00024350153,0.00023974448],"domain_scores_gemma":[0.999184,0.000007381864,0.0001137268,0.00048718276,0.000112585716,0.00009511324],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015320799,0.00030359975,0.00031055885,0.000063966545,0.00003234208,0.00005365013,0.000269557,0.00051896396,0.00019414733],"category_scores_gemma":[0.00003132425,0.00030076798,0.00021629698,0.000048060414,0.0000501952,0.0000013699765,0.0005011794,0.00024753218,0.000019753392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036244193,0.000030704723,0.000066970744,0.0003964843,0.00024044006,0.0000032356595,0.000087902794,0.007099497,0.97989756,0.00017092541,0.011435648,0.00053441216],"study_design_scores_gemma":[0.00035749262,0.00011334197,0.000008218661,0.00012378195,0.00012543258,0.000005479774,0.00010244054,0.008709944,0.97378254,0.00031759727,0.015995305,0.00035844318],"about_ca_topic_score_codex":0.000092769114,"about_ca_topic_score_gemma":0.0000065484714,"teacher_disagreement_score":0.67915106,"about_ca_system_score_codex":0.000026708334,"about_ca_system_score_gemma":0.00007602246,"threshold_uncertainty_score":0.99994445},"labels":[],"label_agreement":null},{"id":"W4399630629","doi":"10.1128/aem.00699-24","title":"A CRISPR-Cas-associated transposon system for genome editing in <i>Burkholderia cepacia</i> complex species","year":2024,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cystic Fibrosis Canada; University of Manitoba; Research Manitoba","keywords":"Transposase; Biology; CRISPR; Burkholderia cepacia complex; Genome editing; Genetics; Computational biology; Genome; Burkholderia cenocepacia; Transposable element; Insertional mutagenesis; Forward genetics; Transposon mutagenesis; Burkholderia; Cas9; Gene; Bacteria","score_opus":0.006589535812835965,"score_gpt":0.21901209948554365,"score_spread":0.21242256367270768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399630629","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99147093,0.0019704264,0.0049883346,0.00005212638,0.00020000925,0.00034421711,0.0005150775,0.000030349878,0.0004285354],"genre_scores_gemma":[0.9975065,0.0001815137,0.00026298777,0.00007216785,0.00018808868,0.00005898346,0.0016116184,0.000029178562,0.000088963156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912167,0.000013489059,0.0001918338,0.00036722753,0.00002060927,0.00028519836],"domain_scores_gemma":[0.9998228,0.000015405549,0.000021653193,0.000098833676,0.0000015426083,0.000039747185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009618871,0.00017130024,0.00018351655,0.000040890016,0.00005489662,0.00001801087,0.00007343116,0.00016406701,0.00001525936],"category_scores_gemma":[0.0000017548614,0.0001734638,0.000057715763,0.000034132772,0.00008360298,0.0000019302895,0.00004806379,0.00007614934,0.000005662303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020888436,0.000022927097,0.0002685235,0.000090292255,0.000042346426,0.0000032850696,0.00016835198,0.00009658883,0.99871796,0.00010193444,0.00015957336,0.00030732932],"study_design_scores_gemma":[0.0013247869,0.00023273734,0.010576854,0.00004715124,0.000052574484,0.00009459917,0.001796785,0.00028859152,0.8920629,0.000024752293,0.09302894,0.00046931583],"about_ca_topic_score_codex":0.0000057986495,"about_ca_topic_score_gemma":0.000022500388,"teacher_disagreement_score":0.10665505,"about_ca_system_score_codex":0.000047125246,"about_ca_system_score_gemma":0.000005871413,"threshold_uncertainty_score":0.7073649},"labels":[],"label_agreement":null},{"id":"W4399708274","doi":"10.1016/j.heliyon.2024.e32964","title":"Development and validation of a ddPCR assay to detect and quantify tobacco DNA in smoke and smokeless tobacco and tobacco-free products","year":2024,"lang":"en","type":"article","venue":"Heliyon","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Universiteit Gent","keywords":"Smokeless tobacco; Tobacco control; Tobacco smoke; Biotechnology; Enforcement; Medicine; Environmental health; Tobacco use; Biology; Population; Public health","score_opus":0.01895996092659571,"score_gpt":0.29303149122975697,"score_spread":0.2740715303031613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399708274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9822853,0.016564714,0.00056073366,0.000205201,0.000087133594,0.0002257085,0.000009635414,0.000011513838,0.000050016406],"genre_scores_gemma":[0.9937384,0.0019258964,0.0041536745,0.00003089346,0.000053050073,0.00002040663,0.000014609393,0.000017710057,0.00004534641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991277,0.000022702241,0.00019987594,0.0003971955,0.000087064225,0.00016545075],"domain_scores_gemma":[0.999667,0.00001974357,0.000021247572,0.0001881295,0.000033496617,0.00007040325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028605506,0.00014479007,0.00015111048,0.000100280704,0.000029006596,0.000054097167,0.0000558226,0.00010045258,0.0000015484469],"category_scores_gemma":[0.000118461394,0.00014091727,0.000011113582,0.00011950476,0.000030696792,0.0000075129246,0.00018966786,0.00006368169,4.4989824e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004717962,0.00001203098,0.028211713,0.0006060335,0.000033806205,0.000006803285,0.0005929504,0.000025363795,0.86099744,0.00006795674,0.000053087762,0.10934564],"study_design_scores_gemma":[0.00033356546,0.00011629737,0.1071775,0.00025933547,0.000014520929,0.000024209176,0.00014151374,0.000016766848,0.88511574,0.000020423924,0.006576334,0.00020379556],"about_ca_topic_score_codex":0.000021682119,"about_ca_topic_score_gemma":0.00023463284,"teacher_disagreement_score":0.10914184,"about_ca_system_score_codex":0.000009934124,"about_ca_system_score_gemma":0.00003827427,"threshold_uncertainty_score":0.57464397},"labels":[],"label_agreement":null},{"id":"W4399708326","doi":"10.1101/2024.06.13.598956","title":"Heterogeneity in establishment of polyethylene glycol-mediated plasmid transformations for five forest pathogenic <i>Phytophthora</i> species","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of British Columbia","funders":"","keywords":"Transformation (genetics); CRISPR; Biology; Plasmid; Phytophthora; Phytophthora sojae; Phytophthora cactorum; Gene; Genetics; Genome editing; Microbiology; Botany","score_opus":0.00893125389799042,"score_gpt":0.2458934859843532,"score_spread":0.23696223208636277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399708326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98182225,0.005463142,0.007850784,0.0001065002,0.0008300907,0.001152802,0.0027006385,0.00006200918,0.000011768092],"genre_scores_gemma":[0.9945932,0.0010140389,0.003401431,0.00005037293,0.00029448816,0.0005144212,0.000019603918,0.00010400932,0.0000084313515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782735,0.00004729561,0.0006804914,0.00074028736,0.00022350812,0.000481089],"domain_scores_gemma":[0.9986478,0.000040482704,0.00017673675,0.0007454941,0.00023580308,0.00015365802],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037021804,0.00046951656,0.0004966913,0.00025763805,0.00005156531,0.000073059105,0.00038826655,0.0005386601,0.0000058942355],"category_scores_gemma":[0.00012396954,0.0005228761,0.00030179266,0.00030679425,0.00008221329,0.000007817802,0.00033046908,0.00036157775,0.0000052816576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076835575,0.00010798464,0.0015665338,0.001033291,0.0001531285,0.000007729273,0.00001943679,0.0037323206,0.99294233,0.000086410924,0.00027156447,0.0000024501699],"study_design_scores_gemma":[0.00068338483,0.00016724097,0.018411271,0.00028807038,0.000106947315,4.7346443e-8,0.000010830113,0.001048865,0.9742891,0.0000064412466,0.0044291904,0.0005585725],"about_ca_topic_score_codex":0.000022661688,"about_ca_topic_score_gemma":0.00008905985,"teacher_disagreement_score":0.018653175,"about_ca_system_score_codex":0.000092129594,"about_ca_system_score_gemma":0.00038984203,"threshold_uncertainty_score":0.9997223},"labels":[],"label_agreement":null},{"id":"W4399718438","doi":"","title":"A Rigorous Framework to Classify the Post-Duplication Fate of Paralogous Genes (extended version)","year":2024,"lang":"en","type":"article","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Gene duplication; Computational biology; Gene; Biology; Computer science; Genetics; Evolutionary biology","score_opus":0.006265830479286927,"score_gpt":0.2571961255543375,"score_spread":0.2509302950750506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399718438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5668033,0.0048755403,0.4150152,0.009290542,0.00018719796,0.0002821546,0.00003598302,0.00006758026,0.003442556],"genre_scores_gemma":[0.98393273,0.00042355445,0.01373236,0.00012852927,0.00003056462,0.00002980307,0.00011072479,0.000019902976,0.0015918332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988445,0.00037156534,0.0001877507,0.00030038873,0.00013536806,0.0001603961],"domain_scores_gemma":[0.99843,0.00020038342,0.00004695133,0.0008145081,0.0004378315,0.000070321636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008346626,0.00011327935,0.00009450648,0.00005145166,0.000106977015,0.00006822134,0.00038951822,0.00010262962,0.000031223855],"category_scores_gemma":[0.00040321008,0.00009458751,0.00008962571,0.00023352698,0.000072321745,0.000004964691,0.00018785273,0.000113253554,0.000032526033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002564481,0.00011497711,0.00047262153,0.00007197064,0.00007886807,0.0000019550046,0.0022989125,0.00043547392,0.87029105,0.022686945,0.0015768735,0.10194473],"study_design_scores_gemma":[0.0001428278,0.0000032325547,0.0076400097,0.00026815434,0.00003119677,0.000016014017,0.00013705652,0.004001169,0.8970909,0.00068574346,0.089783885,0.00019980023],"about_ca_topic_score_codex":0.0001031985,"about_ca_topic_score_gemma":0.00014918188,"teacher_disagreement_score":0.4171295,"about_ca_system_score_codex":0.0000139599215,"about_ca_system_score_gemma":0.0000598812,"threshold_uncertainty_score":0.38571665},"labels":[],"label_agreement":null},{"id":"W4399722310","doi":"10.1038/s41598-024-63943-7","title":"In vitro evolution and whole genome analysis to study chemotherapy drug resistance in haploid human cells","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"U.S. National Library of Medicine; University of California, San Diego; National Institutes of Health; National Institute of General Medical Sciences; Medicines for Malaria Venture; Bill and Melinda Gates Foundation","keywords":"Ploidy; Drug resistance; Genome; In vitro; Drug; Biology; Resistance (ecology); Genetics; Computational biology; Gene; Pharmacology; Ecology","score_opus":0.004307476424224555,"score_gpt":0.2757346658130704,"score_spread":0.2714271893888458,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399722310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960121,0.0019377952,0.0010551747,0.000098914374,0.0005544011,0.00024614134,0.0000025247664,0.000010302684,0.000082671075],"genre_scores_gemma":[0.995152,0.000005452105,0.00035210175,0.000013917708,0.000037175774,0.000022593747,0.000033726465,0.0000109357625,0.0043720803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874353,0.000022009683,0.00026230715,0.0006560091,0.00013995473,0.00017619281],"domain_scores_gemma":[0.99949175,0.0000027833867,0.000025844829,0.0004021233,0.000023287084,0.00005419702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074564974,0.000095272415,0.00012714208,0.00033145995,0.000052840016,0.00010477345,0.000064843356,0.000034474215,0.000009196767],"category_scores_gemma":[0.000009822726,0.000097689845,0.00004599606,0.00082873367,0.00003083253,0.000005085315,0.000050663606,0.000053571814,0.0000021905855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008065202,0.000048605103,0.0016765333,0.000011687732,0.00003650405,0.000096492164,0.00074660266,0.00067785784,0.99612385,0.0000017911764,0.0004858946,0.00008610509],"study_design_scores_gemma":[0.0002196699,0.00003734898,0.04323182,0.000016684908,0.00005441784,0.000008500667,0.00035002883,0.00020423136,0.9161343,0.0004892338,0.038962454,0.00029134084],"about_ca_topic_score_codex":0.00004642589,"about_ca_topic_score_gemma":0.0011001788,"teacher_disagreement_score":0.07998959,"about_ca_system_score_codex":0.000032871085,"about_ca_system_score_gemma":0.000025145211,"threshold_uncertainty_score":0.39836764},"labels":[],"label_agreement":null},{"id":"W4399778949","doi":"10.1016/j.bbrep.2024.101750","title":"Proof of ssDNA degraded from dsDNA for ET recombination","year":2024,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Henan Agricultural University; National Natural Science Foundation of China","keywords":"Nuclease; DNA; Chemistry; Fluorescence; Recombination; Nucleotide; Molecular biology; Electrophoresis; Gel electrophoresis; Double stranded; Biochemistry; Biophysics; Biology; Gene","score_opus":0.00828111073907067,"score_gpt":0.2967364974095882,"score_spread":0.2884553866705175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399778949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830888,0.0029435316,0.013048077,0.00009490731,0.00024391516,0.0001565021,0.0000664094,0.000018367758,0.00033948725],"genre_scores_gemma":[0.9972516,0.00009079142,0.0013819473,0.000016967422,0.00019162268,0.000027079142,0.0005479883,0.000016576214,0.00047544832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992999,0.000005161549,0.00019585171,0.00032724036,0.00007017097,0.000101691025],"domain_scores_gemma":[0.9996319,0.000013732486,0.000056684577,0.00020220074,0.000054273154,0.000041212003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009381894,0.000116462215,0.00010827658,0.000014401454,0.00002159352,0.000024027535,0.000040884475,0.00011445687,0.0000031352622],"category_scores_gemma":[0.000038303755,0.00011133456,0.00008099454,0.000055833716,0.000035829064,0.0000033321808,0.000038065435,0.00004471168,1.7153667e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013102688,0.000032030603,0.00010387407,0.00018784868,0.00005118143,0.0000055313158,0.00002402889,0.000010372255,0.9929421,0.000049325492,0.0006002955,0.0059803096],"study_design_scores_gemma":[0.00010116039,0.00006777122,0.00018821457,0.00005856301,0.000030488563,0.000023458771,0.000020750804,0.00023887596,0.9922235,0.0013864554,0.005524855,0.00013588305],"about_ca_topic_score_codex":0.0000085359125,"about_ca_topic_score_gemma":8.322523e-7,"teacher_disagreement_score":0.014162776,"about_ca_system_score_codex":0.000005433317,"about_ca_system_score_gemma":0.000054765722,"threshold_uncertainty_score":0.45400918},"labels":[],"label_agreement":null},{"id":"W4399830464","doi":"10.1093/ismejo/wrae108","title":"Conditions for the spread of CRISPR-Cas immune systems into bacterial populations","year":2024,"lang":"en","type":"article","venue":"The ISME Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Natural Environment Research Council; Sight Research UK","keywords":"CRISPR; Biology; Population; Immune system; Horizontal gene transfer; Acquired immune system; Bacteria; Microbiology; Genetics; Gene; Genome","score_opus":0.01682747672909287,"score_gpt":0.34670723989606955,"score_spread":0.3298797631669767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399830464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4837047,0.026387535,0.48140165,0.0026026925,0.005179674,0.00041881125,0.00010339919,0.000016110427,0.00018542708],"genre_scores_gemma":[0.99800515,0.00020776622,0.00019901329,0.0000144147225,0.001162676,0.000018324294,0.000027328133,0.000013729882,0.00035157704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952453,0.000025419853,0.00020590071,0.00006898005,0.00007060647,0.00010457407],"domain_scores_gemma":[0.9996538,0.00004326638,0.000043657958,0.00017684985,0.000056746176,0.000025637366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026512766,0.000068655136,0.000075617936,0.000024349925,0.00018183743,0.00007266094,0.00015969852,0.00004449405,0.00002644762],"category_scores_gemma":[0.000040240746,0.000039184903,0.000119174285,0.00004584079,0.000041327366,0.0000030577141,0.000030512112,0.00009471217,0.00000246112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021907364,0.000011599191,0.000026578546,0.00004231934,0.00016191813,8.420087e-7,0.0003085103,0.0099172555,0.97746354,0.0013844827,0.009802549,0.00085852045],"study_design_scores_gemma":[0.0012033008,0.0006232004,0.009291859,0.00032111703,0.0006389913,0.0012289169,0.0020854757,0.026495697,0.5899588,0.0044221017,0.3632571,0.00047343358],"about_ca_topic_score_codex":0.000028744058,"about_ca_topic_score_gemma":0.000011701108,"teacher_disagreement_score":0.51430047,"about_ca_system_score_codex":0.000009048886,"about_ca_system_score_gemma":0.000042997588,"threshold_uncertainty_score":0.1597914},"labels":[],"label_agreement":null},{"id":"W4400026451","doi":"10.1016/j.ymthe.2024.06.033","title":"An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"New Jersey Commission on Cancer Research; AstraZeneca; Rutgers, The State University of New Jersey; U.S. Department of Defense","keywords":"CRISPR; Genome editing; Cas9; Biology; Transcription activator-like effector nuclease; Zinc finger nuclease; Computational biology; Gene knockout; Nuclease; Point mutation; Palindrome; Gene; Genetics; Guide RNA; Gene targeting; Mutation","score_opus":0.012880630262780187,"score_gpt":0.2888587681942645,"score_spread":0.2759781379314843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400026451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.66873723,0.0059800255,0.32412472,0.000045911074,0.00031727154,0.00059111184,0.00015888498,0.000040833278,0.0000039922356],"genre_scores_gemma":[0.985802,0.0004994287,0.01089252,0.00028823648,0.00085206894,0.00015042677,0.0013449516,0.000092662034,0.00007773148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988532,0.000019611332,0.00020861143,0.000513126,0.0000927561,0.00031266944],"domain_scores_gemma":[0.99944603,0.00006124401,0.000032087122,0.00026571573,0.000081705926,0.00011318955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001673549,0.00023499204,0.00015681621,0.0000623497,0.000100312296,0.000087844615,0.0001128767,0.00018103227,0.0000044177295],"category_scores_gemma":[0.00006105149,0.00023247633,0.00012175677,0.00006201188,0.000028259286,0.0000065041077,0.000021200834,0.000061001294,0.0000016637734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007053799,0.000029687304,0.000012210349,0.00004097318,0.00009555798,0.000009929739,0.00010031123,0.018255983,0.9558368,0.000011928155,0.00016607504,0.025370028],"study_design_scores_gemma":[0.0007742652,0.00043761657,0.0000042312695,0.000006755306,0.000021770507,0.000009933477,0.000027570515,0.2207894,0.74879116,0.000017941604,0.028902361,0.00021701763],"about_ca_topic_score_codex":0.000010317827,"about_ca_topic_score_gemma":0.00002306468,"teacher_disagreement_score":0.31706473,"about_ca_system_score_codex":0.000015152408,"about_ca_system_score_gemma":0.000041201434,"threshold_uncertainty_score":0.948011},"labels":[],"label_agreement":null},{"id":"W4400059810","doi":"10.3389/fgeed.2024.1399051","title":"Advancing crop disease resistance through genome editing: a promising approach for enhancing agricultural production","year":2024,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Genome editing; CRISPR; Biotechnology; Agriculture; Biology; Cas9; Disease; Transcription activator-like effector nuclease; Plant disease resistance; Food security; Genetics; Gene; Medicine; Ecology","score_opus":0.011220639106687203,"score_gpt":0.2971227110978861,"score_spread":0.28590207199119894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400059810","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007432741,0.83090025,0.16229841,0.00002919548,0.0045854533,0.0016872663,0.00012068787,0.00006348646,0.00024090898],"genre_scores_gemma":[0.00041825327,0.8599551,0.11069469,0.000017259563,0.022935815,0.0010892897,0.0027452635,0.00024772703,0.0018966317],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99637294,0.0000810541,0.0009426488,0.0014558358,0.00025202025,0.0008954966],"domain_scores_gemma":[0.9988413,0.000017626076,0.00036681138,0.0005030356,0.000110861576,0.00016035362],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006223105,0.0007140919,0.0010849816,0.00019730287,0.00022721883,0.00013969014,0.00039127274,0.00036071666,0.0000015454692],"category_scores_gemma":[0.0005666654,0.0006477289,0.00053812185,0.00044325282,0.00006622001,0.000024694174,0.00020892655,0.0005244848,0.0000021183694],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030577794,0.0005820984,0.00007028283,0.5577032,0.003268337,0.00017318,0.0051784115,0.034270406,0.04962985,0.000103693856,0.08595474,0.26276004],"study_design_scores_gemma":[0.00019483878,0.000041525927,0.0000081466615,0.0054698177,0.0006933464,0.00002299272,0.00084378675,0.00011646607,0.0003317025,0.000048763108,0.99132776,0.00090083695],"about_ca_topic_score_codex":0.0000018726165,"about_ca_topic_score_gemma":0.000012394709,"teacher_disagreement_score":0.90537304,"about_ca_system_score_codex":0.00034071217,"about_ca_system_score_gemma":0.00023407082,"threshold_uncertainty_score":0.9995974},"labels":[],"label_agreement":null},{"id":"W4400102166","doi":"10.1016/j.jare.2024.06.021","title":"Developing a multi-modular assembled prime editing (mPE) system improved precise multi-base insertion efficiency in dicots","year":2024,"lang":"en","type":"article","venue":"Journal of Advanced Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Chinese Academy of Agricultural Sciences; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Nicotiana benthamiana; Guide RNA; Computational biology; Modular design; Transformation (genetics); Arabidopsis; Genome editing; Cas9; Biology; Amplicon; Transformation efficiency; Computer science; CRISPR; Agrobacterium; Gene; Genetics; Operating system","score_opus":0.03714369264113712,"score_gpt":0.414327786422013,"score_spread":0.3771840937808759,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400102166","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75090194,0.005845281,0.24247171,0.000056779107,0.000446395,0.00024356588,0.0000018394492,0.000012703677,0.000019779665],"genre_scores_gemma":[0.9732597,0.00034064043,0.025901372,0.00000493478,0.00033703883,0.000017953584,0.0000043341333,0.00003231064,0.00010174982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827635,0.00013932712,0.00050619396,0.0002891165,0.00036474393,0.00042424176],"domain_scores_gemma":[0.99916303,0.00006269674,0.00008316045,0.00019303283,0.00037883272,0.00011921615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016924794,0.0001408083,0.00020687035,0.00038091102,0.000080081896,0.00007052997,0.00024326015,0.0001278236,0.0000012312435],"category_scores_gemma":[0.00064783084,0.0001228687,0.000099408506,0.00042921587,0.000028455437,0.00002013069,0.00012079578,0.00052063394,0.000003333508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008314014,0.000066603905,0.00023262354,0.0002833469,0.000026619979,0.00006989376,0.00013192442,0.011401612,0.97695196,0.000008723765,0.000015083349,0.010728498],"study_design_scores_gemma":[0.0014675597,0.0003436896,0.0029854744,0.0011443704,0.000008522703,0.000108007145,0.00073344086,0.06275686,0.9290401,0.0000052504515,0.0012348724,0.0001718978],"about_ca_topic_score_codex":0.00001019496,"about_ca_topic_score_gemma":0.00003171747,"teacher_disagreement_score":0.22235772,"about_ca_system_score_codex":0.0002174133,"about_ca_system_score_gemma":0.00033110872,"threshold_uncertainty_score":0.50104403},"labels":[],"label_agreement":null},{"id":"W4400139313","doi":"10.5376/ijh.2024.14.0016","title":"Developing Citrus Germplasm Resistant to Asian Citrus Psyllid Using CRISPR/Cas9 Gene Editing Technology: Recent Advances and Challenges","year":2024,"lang":"en","type":"article","venue":"International Journal of Horticulture","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Germplasm; Cas9; Biology; Biotechnology; Sustainability; Gene; Genetics; Agronomy; Ecology","score_opus":0.017936032506291007,"score_gpt":0.34115954655701236,"score_spread":0.32322351405072136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400139313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7560782,0.19712228,0.030347394,0.013777508,0.002175714,0.00012125101,0.000023663593,0.0000283667,0.00032561625],"genre_scores_gemma":[0.9227136,0.041088384,0.0343342,0.00013769386,0.001652856,0.000004190968,0.000005439324,0.00002477564,0.00003885388],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999046,0.000013079284,0.00032012476,0.00021535563,0.00023889795,0.00016649088],"domain_scores_gemma":[0.99941456,0.000009273988,0.00008724394,0.00007097529,0.00033727588,0.00008067867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014198161,0.00014188015,0.00014042453,0.00018015354,0.00004468483,0.00008059977,0.00020692521,0.00011880804,0.0000058476503],"category_scores_gemma":[0.00017257905,0.000115900024,0.000059496695,0.00011219867,0.000028642035,0.000015976078,0.00010158216,0.00016690872,0.0000012081991],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008269835,0.000018100649,0.0001274311,0.000072984105,0.0003405235,0.00026830105,0.00042202568,0.00095769303,0.86162794,0.00042992833,0.00034869442,0.13530368],"study_design_scores_gemma":[0.00028131533,0.00021433752,0.00077056006,0.0005216802,0.000049464954,0.0025551706,0.0017545804,0.00015397776,0.44423288,0.00049245346,0.548703,0.00027057985],"about_ca_topic_score_codex":8.605479e-7,"about_ca_topic_score_gemma":0.000018529996,"teacher_disagreement_score":0.5483543,"about_ca_system_score_codex":0.000064365275,"about_ca_system_score_gemma":0.00007141443,"threshold_uncertainty_score":0.4726266},"labels":[],"label_agreement":null},{"id":"W4400279651","doi":"10.1038/s41586-024-07642-3","title":"An anti-CRISPR that pulls apart a CRISPR–Cas complex","year":2024,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Beijing Municipal Science and Technology Commission; National Natural Science Foundation of China","keywords":"CRISPR; Computational biology; Steric effects; Chemistry; Function (biology); Biology; Biochemistry; Genetics; Stereochemistry; Gene","score_opus":0.010940273643457878,"score_gpt":0.3448317198697604,"score_spread":0.3338914462263025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400279651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91451675,0.041907255,0.0325618,0.0017692114,0.0025565757,0.00043231633,0.0001783236,0.00029297918,0.0057847663],"genre_scores_gemma":[0.99634784,0.00027000118,0.0009191905,0.00093336764,0.0006798233,0.00000913271,0.00027402877,0.000041431646,0.0005251876],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99903345,0.000021236352,0.00010942972,0.00041454015,0.00015164647,0.00026968677],"domain_scores_gemma":[0.9994395,0.000008049738,0.000013967753,0.00039379968,0.000039022478,0.00010569963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103374165,0.00018242911,0.00013221856,0.000054505486,0.00005301545,0.00009123375,0.00021823322,0.0007942302,0.000085063715],"category_scores_gemma":[0.000019351211,0.0001655161,0.00010268338,0.00011422209,0.000030955784,0.0000053632693,0.00005824395,0.0006908595,0.000034490593],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013208601,0.000035151163,0.0007190543,0.00007526073,0.00006301519,0.000036402114,0.000085125765,0.00026030836,0.93274385,0.0002681858,0.062527366,0.0031731015],"study_design_scores_gemma":[0.00015036661,0.000101745645,0.0065477076,0.000024204715,0.00002616189,0.00006527935,0.000056905807,0.001288696,0.49361676,0.000057445228,0.4978167,0.00024800716],"about_ca_topic_score_codex":0.000007063445,"about_ca_topic_score_gemma":0.000019445375,"teacher_disagreement_score":0.43912706,"about_ca_system_score_codex":0.000010192236,"about_ca_system_score_gemma":0.000034078734,"threshold_uncertainty_score":0.67495507},"labels":[],"label_agreement":null},{"id":"W4400286327","doi":"10.1121/10.0027680","title":"Focused ultrasound-guided delivery of gene editing protein in human induced pluripotent stem cells","year":2024,"lang":"en","type":"article","venue":"The Journal of the Acoustical Society of America","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Induced pluripotent stem cell; Stem cell; Gene delivery; Genome editing; Gene; Human Induced Pluripotent Stem Cells; Cell biology; Computational biology; Ultrasound; Biology; Embryonic stem cell; Genetics; Genetic enhancement; CRISPR; Medicine","score_opus":0.011698533366285492,"score_gpt":0.268639245037062,"score_spread":0.2569407116707765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400286327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9435825,0.0009464091,0.05482102,0.00031815853,0.00016053759,0.00013934886,0.0000070510564,0.0000033432489,0.000021644992],"genre_scores_gemma":[0.9931435,0.00017271175,0.006280905,0.000082932456,0.00026199888,0.000001507781,5.9415225e-7,0.000016174195,0.000039685627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896634,0.00007694956,0.00044415626,0.00009442194,0.00024819648,0.00016992635],"domain_scores_gemma":[0.9993883,0.0000770563,0.00018723262,0.00020882211,0.00009590123,0.00004269483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041520587,0.00011086623,0.00021320369,0.000018091094,0.000044988617,0.000009624665,0.00034776272,0.000081075,0.0000068726904],"category_scores_gemma":[0.000039641473,0.00006707395,0.000295913,0.00015417977,0.00015475371,0.0000037751718,0.000094816845,0.00027043695,3.506787e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019805564,0.00003865652,0.00002644287,0.00007462793,0.00011401183,9.4444226e-7,0.00027461193,0.010002152,0.9858742,8.243354e-7,0.0015166807,0.0020570676],"study_design_scores_gemma":[0.00024208498,0.00026375186,0.00018332353,0.00014907669,0.000086563035,0.000035402765,0.0008883067,0.0058010085,0.9919939,0.000038396094,0.00024159912,0.000076589626],"about_ca_topic_score_codex":0.00003999063,"about_ca_topic_score_gemma":0.0000010020213,"teacher_disagreement_score":0.049561005,"about_ca_system_score_codex":0.000027179669,"about_ca_system_score_gemma":0.00007330541,"threshold_uncertainty_score":0.2735196},"labels":[],"label_agreement":null},{"id":"W4400303479","doi":"10.1038/s42003-024-06422-z","title":"Structure and engineering of Brevibacillus laterosporus Cas9","year":2024,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Bio-oriented Technology Research Advancement Institution; Japan Society for the Promotion of Science; Cabinet Office, Government of Japan; Core Research for Evolutional Science and Technology; Japan Agency for Medical Research and Development","keywords":"Biology; Microbiology","score_opus":0.009475952932286622,"score_gpt":0.3242820316779139,"score_spread":0.31480607874562727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400303479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93319523,0.05894241,0.007049683,0.00024248403,0.00015530217,0.00008671744,0.0000776326,0.000027938657,0.00022260251],"genre_scores_gemma":[0.99389,0.0017986358,0.004084765,0.00001621597,0.00003351632,0.000005009389,0.00011459386,0.000009553392,0.000047729573],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996649,0.000014918398,0.000110336936,0.00011502346,0.000013533655,0.00008127106],"domain_scores_gemma":[0.99942636,0.000020183064,0.000012352297,0.0004975434,0.000020116442,0.00002345491],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004902873,0.00006682734,0.00007804858,0.000038489514,0.000027916318,0.000009866897,0.000186282,0.00008761707,0.000007145349],"category_scores_gemma":[0.000024885774,0.00006208791,0.000025284076,0.00006033855,0.00009501578,0.000001212273,0.00019819195,0.00007038296,0.0000011309628],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000019957129,0.000004568573,0.0015136985,0.00004721273,0.000040498864,2.8739228e-7,0.000073794836,0.00009134456,0.9874516,0.003117866,0.00008281268,0.0075743226],"study_design_scores_gemma":[0.00035728415,0.0002916964,0.014923848,0.000106802894,0.00006847972,0.0001791044,0.000060922153,0.010333335,0.4606613,0.0007093948,0.5118438,0.00046404413],"about_ca_topic_score_codex":0.000008973622,"about_ca_topic_score_gemma":0.000013022199,"teacher_disagreement_score":0.5267903,"about_ca_system_score_codex":0.0000032004525,"about_ca_system_score_gemma":0.000016597518,"threshold_uncertainty_score":0.25318715},"labels":[],"label_agreement":null},{"id":"W4400358597","doi":"10.1007/978-1-0716-4031-9_14","title":"CRISPR-Cas9 Technology in Plant Genomics Research: A Review and Tutorial for Implementation with Considerations for Orchid Genetic Studies","year":2024,"lang":"en","type":"review","venue":"Springer protocols handbooks/Springer protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Genomics; Computational biology; Biology; Computer science; Biotechnology; Genetics; Genome; Gene","score_opus":0.20903192246670224,"score_gpt":0.5247844328368378,"score_spread":0.31575251037013563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400358597","genre_codex":"review","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000071830214,0.52916646,0.001307271,0.0000795153,0.000074249874,0.46910036,0.000210566,0.00004673957,0.000007673339],"genre_scores_gemma":[0.000003549306,0.37658784,0.010910807,0.00003081309,0.0005177746,0.6116742,0.0000508822,0.00015055687,0.00007358633],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99560326,0.00018783122,0.0013975996,0.0015410165,0.00029838333,0.00097192003],"domain_scores_gemma":[0.997896,0.00021197242,0.0003626986,0.00092954707,0.00044712808,0.00015263555],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015924338,0.0008577114,0.0018800092,0.00063580606,0.00025750312,0.00023545293,0.0004211109,0.00053930085,0.000007811547],"category_scores_gemma":[0.00041549848,0.0007049397,0.00031687066,0.00035527837,0.00026356927,0.000014066053,0.0005450544,0.0006150315,0.0000059373174],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006765954,0.00030534904,0.00007769843,0.6928266,0.0028653522,0.00008311521,0.00062929257,0.0000318945,0.006776057,0.0031760242,0.010864399,0.2816876],"study_design_scores_gemma":[0.0018699775,0.0016143634,0.0000021024707,0.042187545,0.00068343955,0.00008608437,0.000050994455,0.000007910301,0.0061846767,0.0010406451,0.94546217,0.0008101115],"about_ca_topic_score_codex":0.000007426744,"about_ca_topic_score_gemma":0.00017081751,"teacher_disagreement_score":0.93459773,"about_ca_system_score_codex":0.00022310967,"about_ca_system_score_gemma":0.0010881317,"threshold_uncertainty_score":0.99954015},"labels":[],"label_agreement":null},{"id":"W4400477573","doi":"10.1101/2024.07.04.602122","title":"Heli-SMACC: Helicase-targeting SMAll Molecule Compound Collection","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"","keywords":"Helicase; Chemistry; Biochemistry","score_opus":0.009646918847960899,"score_gpt":0.24458818718492206,"score_spread":0.23494126833696116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400477573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9757202,0.011566493,0.009033031,0.00017082004,0.0022813121,0.00066273287,0.00017528067,0.00032336262,0.000066713226],"genre_scores_gemma":[0.9920085,0.00070758775,0.0052502723,0.00017007669,0.0013676115,0.00019928976,0.000005394853,0.00022733865,0.00006390573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99722975,0.000080347854,0.0005302091,0.0012834234,0.00025253923,0.00062370923],"domain_scores_gemma":[0.9982144,0.000018764193,0.00017313453,0.0010130988,0.00031422306,0.00026636384],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041328013,0.00064875593,0.00043944013,0.00021974745,0.00016650006,0.00026451357,0.00045507555,0.0007230522,0.000027373397],"category_scores_gemma":[0.00015452936,0.0007517839,0.00027894188,0.00036290343,0.00007302286,0.0000034678162,0.0010795092,0.0007651885,0.00007054641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028779017,0.00006149737,0.00028079125,0.0004687354,0.00021983046,0.000059720198,0.000007811483,0.00081695156,0.99460834,0.00003947961,0.0034062206,0.0000018416929],"study_design_scores_gemma":[0.00032902084,0.00010255442,0.0009078618,0.0002486543,0.00014306822,1.788702e-7,0.000005521668,0.0017822831,0.9810269,0.0000031764755,0.014548029,0.00090277934],"about_ca_topic_score_codex":0.000058638492,"about_ca_topic_score_gemma":0.000012321784,"teacher_disagreement_score":0.016288267,"about_ca_system_score_codex":0.00013570247,"about_ca_system_score_gemma":0.00044266885,"threshold_uncertainty_score":0.9994933},"labels":[],"label_agreement":null},{"id":"W4400477690","doi":"10.1101/2024.07.06.602340","title":"Structural impact of synonymous mutations in six SARS-CoV-2 Variants of Concern","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Genetics; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Biology; Silent mutation; Mutation; Sars virus; Computational biology; Gene; Medicine; Disease; Missense mutation","score_opus":0.015058642529833645,"score_gpt":0.29891329465621574,"score_spread":0.2838546521263821,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400477690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954889,0.0026044447,0.0004914341,0.000012005668,0.00048504636,0.00031795993,0.0005590937,0.000028603305,0.000012512606],"genre_scores_gemma":[0.9985521,0.000101310434,0.0010704156,0.000009314093,0.00015665012,0.000030597766,0.0000023051716,0.0000753274,0.0000019997506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984229,0.000046155026,0.0005246017,0.00054473977,0.00016333179,0.00029822235],"domain_scores_gemma":[0.9987936,0.000016035043,0.00020812928,0.00070191454,0.00021627879,0.00006402907],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018399522,0.0003475891,0.00044446415,0.00020316576,0.000018692825,0.0000294969,0.0002960647,0.00041009835,0.000009093666],"category_scores_gemma":[0.00011471692,0.00035730324,0.00023668718,0.00026598523,0.00010187112,0.0000035218477,0.00041428852,0.00033791427,0.0000038427806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029139432,0.000030068139,0.0047688955,0.00040453012,0.00022199322,0.000015411933,0.000014986364,0.003976257,0.99041617,0.00005404489,0.00006611448,0.000002382705],"study_design_scores_gemma":[0.000303706,0.00010421696,0.12563379,0.00023228824,0.00007295552,5.9208254e-8,0.0000024732678,0.0014210865,0.87185895,0.000005385862,0.000040959818,0.00032414004],"about_ca_topic_score_codex":0.00027266511,"about_ca_topic_score_gemma":0.000018703446,"teacher_disagreement_score":0.12086489,"about_ca_system_score_codex":0.00007273016,"about_ca_system_score_gemma":0.0005387431,"threshold_uncertainty_score":0.9998879},"labels":[],"label_agreement":null},{"id":"W4400489705","doi":"10.2139/ssrn.4784002","title":"Exploring DNA Analysis Methods and Genetic Research Applications in Low and Middle-Income Nations: A Study of Sri Lanka","year":2024,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Health and Long Term Care","funders":"","keywords":"Sri lanka; Low and middle income countries; Socioeconomics; Development economics; Economic growth; Geography; Developing country; Economics; Tanzania","score_opus":0.04814261107569804,"score_gpt":0.4139573236939704,"score_spread":0.36581471261827236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400489705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95058763,0.022065954,0.027095934,0.000026800355,0.000019346533,0.00016744496,0.0000014264058,0.0000043746636,0.000031060023],"genre_scores_gemma":[0.9854657,0.013224969,0.001125503,0.0000011879512,0.0000691313,0.00006217074,0.0000030365745,0.000010068117,0.000038235517],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988079,0.00013018354,0.00021608961,0.00022504428,0.00012240614,0.0004983841],"domain_scores_gemma":[0.99966186,0.00006781182,0.000022771692,0.00014570482,0.00005598222,0.000045887053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001328697,0.000081770224,0.00013076777,0.0005549429,0.00007946064,0.0000377416,0.00009776131,0.0000395849,0.0000013812538],"category_scores_gemma":[0.00005429666,0.00007593239,0.00004074883,0.0007751396,0.000030280866,0.000006328405,0.00006604918,0.00043806387,2.4797336e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020502592,0.0014223561,0.1978911,0.0014956363,0.009983192,0.00004726108,0.028521951,0.020723455,0.51336765,0.013701568,0.000003710788,0.21263708],"study_design_scores_gemma":[0.0071578054,0.009605849,0.4761709,0.0012244335,0.003303175,0.0014450217,0.27257612,0.032856617,0.14409831,0.04500746,0.0038746267,0.0026796523],"about_ca_topic_score_codex":0.00004734751,"about_ca_topic_score_gemma":0.0014688991,"teacher_disagreement_score":0.36926934,"about_ca_system_score_codex":0.00005549732,"about_ca_system_score_gemma":0.0001815809,"threshold_uncertainty_score":0.30964327},"labels":[],"label_agreement":null},{"id":"W4400513145","doi":"10.21203/rs.3.rs-4559920/v1","title":"The Retrotransposon-Derived Capsid Genes PNMA1 and PNMA4 Maintain Reproductive Capacity","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Irving Medical Center, Columbia University; National Institute of Food and Agriculture; National Institutes of Health; Buck Institute for Research on Aging; Echo Foundation; Wellcome Trust; Montana State University; M.J. Murdock Charitable Trust; U.S. Department of Agriculture","keywords":"Retrotransposon; Biology; Gene; Capsid; Genome; Offspring; Genetics; Mutant; Domestication","score_opus":0.03267467060534194,"score_gpt":0.3797483501532213,"score_spread":0.3470736795478793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400513145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94500375,0.049779486,0.00083602755,0.0018627819,0.0005130674,0.0010100651,0.00019126137,0.000043812677,0.0007597357],"genre_scores_gemma":[0.98639274,0.010482473,0.0005075542,0.000013472267,0.0011584465,0.00026091302,0.00012014528,0.00007362267,0.0009906375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971387,0.0003142187,0.00026046042,0.001142568,0.0004862701,0.0006578142],"domain_scores_gemma":[0.99813205,0.00007750624,0.000037417736,0.001228366,0.00035449857,0.0001701688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017318284,0.0003074235,0.00024162346,0.00011094737,0.00034033295,0.00021931232,0.00043489577,0.00041542685,0.000010139326],"category_scores_gemma":[0.0004015596,0.00024013247,0.00016079487,0.00016033313,0.0004472018,0.0000016564828,0.001496034,0.0013668827,0.000015087534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024301617,0.000055068806,0.0010520119,0.0021890737,0.00051716284,0.000063092186,0.0009354656,0.0010754484,0.97387934,0.0017250091,0.0045385836,0.013726728],"study_design_scores_gemma":[0.0003960355,0.0005623185,0.0069388053,0.00059743674,0.000070630624,0.00006565682,0.0016902443,0.00062274636,0.9032334,0.016390668,0.06858274,0.0008493229],"about_ca_topic_score_codex":0.00023481724,"about_ca_topic_score_gemma":0.00029322103,"teacher_disagreement_score":0.07064594,"about_ca_system_score_codex":0.00006846025,"about_ca_system_score_gemma":0.00023213951,"threshold_uncertainty_score":0.9792318},"labels":[],"label_agreement":null},{"id":"W4400513381","doi":"10.1101/2024.07.09.602704","title":"Deletion of HindIIR and HindIIIR improves DNA transfer via electroporation to <i>Haemophilus influenzae</i> Rd","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Electroporation; Haemophilus influenzae; Microbiology; Gene transfer; DNA; Chemistry; Genetics; Biology; Gene; Antibiotics","score_opus":0.004952978167408481,"score_gpt":0.23014769337660818,"score_spread":0.2251947152091997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400513381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97435987,0.003805727,0.020412205,0.00015493065,0.0004231442,0.000628655,0.00012784355,0.00008193732,0.0000056832173],"genre_scores_gemma":[0.99687105,0.0004050093,0.0019012336,0.0001638995,0.00042796566,0.00010744147,0.0000038665703,0.000114264934,0.0000052424057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980614,0.0000419896,0.0004658005,0.0008438022,0.00021816391,0.00036884553],"domain_scores_gemma":[0.9988126,0.0000079806,0.0000851156,0.0006695127,0.00022774792,0.00019703663],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002737179,0.0004459861,0.00037985394,0.0002042107,0.00005567777,0.00008295848,0.00024410902,0.0005381991,0.000004270856],"category_scores_gemma":[0.000049748633,0.00048986584,0.00013097955,0.00023451528,0.00006236798,0.0000064253372,0.00033239747,0.0003801179,0.000008675292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053952088,0.000035233534,0.00018214811,0.0005174402,0.00013363778,0.000005832461,0.000018330516,0.0002242825,0.9984787,0.00009818282,0.00021834693,0.00003390864],"study_design_scores_gemma":[0.00026347546,0.00025214758,0.007917966,0.00011948026,0.00012085505,8.753729e-8,0.0000019558495,0.0002474809,0.98685503,0.000012036942,0.0036911853,0.00051830884],"about_ca_topic_score_codex":0.000030569758,"about_ca_topic_score_gemma":0.000009113846,"teacher_disagreement_score":0.022511203,"about_ca_system_score_codex":0.000055656452,"about_ca_system_score_gemma":0.00021129935,"threshold_uncertainty_score":0.9997553},"labels":[],"label_agreement":null},{"id":"W4400526195","doi":"10.17975/sfj-2024-007","title":"CRISPR technology for Parkinson’s disease: Recent advancements and ongoing challenges","year":2024,"lang":"en","type":"article","venue":"STEM Fellowship Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Parkinson's disease; Disease; Computational biology; Biology; Computer science; Medicine; Genetics; Gene; Pathology","score_opus":0.01952117277488391,"score_gpt":0.32370279614734077,"score_spread":0.30418162337245686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400526195","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2556435,0.6549782,0.079976305,0.006264382,0.0019908072,0.00045005244,0.000034218123,0.00007959691,0.00058294245],"genre_scores_gemma":[0.9275375,0.06952335,0.0015550203,0.000060875696,0.0005967989,0.000039913833,0.00000915895,0.000037500442,0.0006399114],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991794,0.000016014548,0.00017552057,0.00027494517,0.00009202131,0.00026209894],"domain_scores_gemma":[0.99961394,0.000014178369,0.000030033967,0.00014743784,0.000054629087,0.00013980962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021233773,0.00013711749,0.000108602864,0.00009850298,0.000097935685,0.00006451651,0.00010930184,0.00008812286,0.000008484724],"category_scores_gemma":[0.00003394083,0.00012550356,0.00006329715,0.00006112364,0.000032304193,0.000005366403,0.000058312085,0.00013298162,0.000002655991],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019694852,0.000058785125,0.0019928133,0.0006677052,0.0003039416,0.00007973924,0.0002537126,0.00034286932,0.11972816,0.0010922962,0.0043434356,0.8709396],"study_design_scores_gemma":[0.00036998632,0.00021287779,0.00052605884,0.00016355538,0.000044773325,0.00013600811,0.00041410097,0.0003522671,0.024378806,0.0007936253,0.97240806,0.0001998873],"about_ca_topic_score_codex":1.4566146e-7,"about_ca_topic_score_gemma":0.0000038123349,"teacher_disagreement_score":0.9680646,"about_ca_system_score_codex":0.000021182974,"about_ca_system_score_gemma":0.000058441037,"threshold_uncertainty_score":0.51178867},"labels":[],"label_agreement":null},{"id":"W4400590870","doi":"10.1093/nar/gkae604","title":"Conformational dynamics of CasX (Cas12e) in mediating DNA cleavage revealed by single-molecule FRET","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Ministry of Agriculture - Saskatchewan; Beijing Frontier Research Center for Biological Structure, Tsinghua University","keywords":"Biology; Cas9; CRISPR; Cleavage (geology); DNA; Förster resonance energy transfer; Genome editing; Computational biology; Effector; Biophysics; Genome; Nuclease; Genetics; Cell biology; Gene; Fluorescence","score_opus":0.018065483836988038,"score_gpt":0.35017030292495793,"score_spread":0.3321048190879699,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400590870","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98847884,0.0013371747,0.0025129756,0.00029890222,0.00009833976,0.00017915656,0.00012018073,0.000016872555,0.00695755],"genre_scores_gemma":[0.99841386,0.00012913113,0.0004694195,0.000023520657,0.00009437279,0.000014182282,0.0002941913,0.000028413428,0.00053291954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865746,0.00007084663,0.0002950693,0.0002471569,0.00038759958,0.0003418613],"domain_scores_gemma":[0.99950975,0.00006358969,0.000022359027,0.00023178714,0.000096111326,0.00007638137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074760313,0.00010623311,0.0001269768,0.00015666164,0.00004254759,0.000039565133,0.00021827752,0.00015651736,0.000046924855],"category_scores_gemma":[0.00021906117,0.00010959554,0.00005265265,0.0003098044,0.00010723905,0.0000073359806,0.00015982157,0.00027954622,0.000016288657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026441548,0.000035831792,0.000989173,0.00017907251,0.000025260264,0.000013253452,0.00024865137,0.000090071095,0.98694634,0.0003785026,0.006318731,0.004748647],"study_design_scores_gemma":[0.0006563246,0.00048380572,0.0019036498,0.00015688775,0.000007990766,0.00003138307,0.00073876884,0.044086736,0.93763095,0.00025115837,0.013742002,0.000310333],"about_ca_topic_score_codex":0.000042009735,"about_ca_topic_score_gemma":0.00006748156,"teacher_disagreement_score":0.049315404,"about_ca_system_score_codex":0.00006659475,"about_ca_system_score_gemma":0.00009235366,"threshold_uncertainty_score":0.44691762},"labels":[],"label_agreement":null},{"id":"W4400613718","doi":"10.1186/s44316-024-00007-w","title":"Inexpensive and colorimetric RNA detection at ambient temperature with a cell-free protein synthesis platform","year":2024,"lang":"en","type":"article","venue":"Biotechnology for Sustainable Materials","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"RNA; lac operon; Gene expression; Complementation; In vitro; Translation (biology); Cell; Transcription (linguistics); Gene; Chemistry; Computational biology; Messenger RNA; Molecular biology; Cell biology; Biology; Biochemistry","score_opus":0.0033073576860506286,"score_gpt":0.22079938869469337,"score_spread":0.21749203100864276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400613718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951711,0.001770311,0.0016095064,0.00022512164,0.00011517307,0.00092194666,0.00004145322,0.00010307625,0.000042281434],"genre_scores_gemma":[0.99688554,0.00012193386,0.00065140263,0.000016678969,0.00009231296,0.000569498,0.000025215722,0.00004248819,0.001594903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990065,0.00001083046,0.00015354184,0.00040969264,0.000061866696,0.00035754291],"domain_scores_gemma":[0.99951327,0.00001668929,0.000038812846,0.00031521497,0.00007463056,0.00004139711],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015456698,0.00019088385,0.00018133437,0.00021899946,0.00013659195,0.000085055115,0.00013529371,0.00048288298,0.000010496298],"category_scores_gemma":[0.00017771387,0.00016083021,0.00003441374,0.00021697558,0.000084271036,0.000007274871,0.00023895479,0.00006843082,0.0000019911365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026567988,0.000012979344,0.0000017383196,0.0005935352,0.00005170519,0.000031884407,0.000022179864,0.000010753844,0.9974726,0.000488872,0.00048670126,0.00056139124],"study_design_scores_gemma":[0.00035546182,0.0007617485,0.000016064663,0.000032592605,0.00004258633,0.000068289686,0.00040432965,0.0000114775585,0.97661704,0.0002091095,0.021270905,0.00021042478],"about_ca_topic_score_codex":0.0000360838,"about_ca_topic_score_gemma":0.000018424022,"teacher_disagreement_score":0.020855568,"about_ca_system_score_codex":0.000064702916,"about_ca_system_score_gemma":0.000046607092,"threshold_uncertainty_score":0.65584654},"labels":[],"label_agreement":null},{"id":"W4400656656","doi":"10.21203/rs.3.rs-4622751/v1","title":"Discovery of the Widespread Site-Specific Single-Stranded Nuclease Family Ssn","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada","keywords":"Nuclease; Homing endonuclease; DNA; SUPERFAMILY; Biology; Computational biology; Cleavage (geology); Gene; Restriction enzyme; Genetics; Genome; Cell biology","score_opus":0.04179977711291938,"score_gpt":0.3684182810797963,"score_spread":0.3266185039668769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400656656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97991633,0.014199923,0.0006245593,0.00026088036,0.0006895643,0.0006416283,0.0004581333,0.00002247266,0.0031864871],"genre_scores_gemma":[0.99582523,0.0012118036,0.0001276617,0.000016047414,0.00045934087,0.000049516817,0.00016327646,0.000069442736,0.0020777052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781394,0.00016951817,0.00030496065,0.00064798363,0.0006194963,0.00044410484],"domain_scores_gemma":[0.99834806,0.00006398106,0.00005032024,0.0012255628,0.00022299486,0.00008910808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050679874,0.00025540774,0.00024329186,0.00012404464,0.000081357524,0.00015565877,0.0006122622,0.00037142326,0.000016789714],"category_scores_gemma":[0.00017890596,0.00019612849,0.00036892257,0.00021258701,0.00023476244,0.0000018181083,0.0022938896,0.0009479023,0.000026338004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000091847745,0.000089750305,0.0002060767,0.0010358255,0.00007350023,0.0000121002795,0.000158737,0.0015313372,0.98457056,0.000107449094,0.01046216,0.0016606448],"study_design_scores_gemma":[0.00039289298,0.00029718122,0.0038685333,0.0014886258,0.000039873525,0.0000072826474,0.000444298,0.0002488248,0.9493893,0.0013129415,0.042077772,0.00043247372],"about_ca_topic_score_codex":0.00007320973,"about_ca_topic_score_gemma":0.000060955303,"teacher_disagreement_score":0.035181273,"about_ca_system_score_codex":0.000054298624,"about_ca_system_score_gemma":0.0002399267,"threshold_uncertainty_score":0.7997888},"labels":[],"label_agreement":null},{"id":"W4400663968","doi":"10.1016/j.mocell.2024.100092","title":"Unlocking biological mechanisms with integrative functional genomics approaches","year":2024,"lang":"en","type":"review","venue":"Molecules and Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Research Foundation of Korea; Korea University; National Research Foundation","keywords":"CRISPR; Functional genomics; Computational biology; Genomics; Epigenetics; Biology; Chromatin; Personalized medicine; Genome editing; Epigenomics; Precision medicine; Cas9; Gene; Genetics; Genome; Gene expression; DNA methylation","score_opus":0.039900635886927924,"score_gpt":0.28251333260852785,"score_spread":0.2426126967215999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400663968","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007800779,0.90004796,0.099054724,0.000005883401,0.00013115315,0.00023562455,0.000045937824,0.000016115799,0.0003846195],"genre_scores_gemma":[0.0003932837,0.99505055,0.0034002815,0.000024674142,0.00017752737,0.00006182886,0.00032477156,0.000054930886,0.000512146],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989458,0.00003458451,0.00019866697,0.00054238614,0.000073382915,0.00020520712],"domain_scores_gemma":[0.99966025,0.000009952814,0.00005546689,0.00018420907,0.000017126475,0.00007296159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007495749,0.00038796113,0.00047269498,0.00005507819,0.00004805866,0.000058478476,0.000109731336,0.00030061163,0.000008285216],"category_scores_gemma":[0.000003928536,0.00023506407,0.00018715754,0.00007822836,0.000063384694,9.5100506e-7,0.0001531327,0.00021683218,0.000011852589],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045680852,0.00008479469,7.3857655e-7,0.0068339272,0.0013812026,0.00007341085,0.00012874899,0.00026978372,0.0166703,0.005365608,0.0016133889,0.9675324],"study_design_scores_gemma":[0.00009544938,0.00028516146,4.849777e-7,0.0009286264,0.00045612227,0.000122030855,0.00012336376,0.0000835528,0.0053981887,0.00015186434,0.99187356,0.00048160474],"about_ca_topic_score_codex":0.0000017123139,"about_ca_topic_score_gemma":0.0000034716302,"teacher_disagreement_score":0.9902602,"about_ca_system_score_codex":0.000016157685,"about_ca_system_score_gemma":0.00007794926,"threshold_uncertainty_score":0.95856345},"labels":[],"label_agreement":null},{"id":"W4400748592","doi":"10.1016/j.cbpa.2024.111703","title":"Knock down to level up: Reframing RNAi for invertebrate ecophysiology","year":2024,"lang":"en","type":"review","venue":"Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Francis Xavier University; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RNA interference; Biology; Gene knockdown; Computational biology; Model organism; Gene; Ecology; Bioinformatics; Genetics; RNA","score_opus":0.05493338284927025,"score_gpt":0.3931960001948545,"score_spread":0.33826261734558427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400748592","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015345742,0.9759507,0.0037967707,0.0000489002,0.001513105,0.0017251109,0.0013544654,0.00006971604,0.00019544916],"genre_scores_gemma":[0.051594418,0.92711675,0.0019193157,0.0007658411,0.002259462,0.0034713056,0.009121577,0.00029691137,0.0034544116],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99503744,0.00040556563,0.0009808408,0.0024705245,0.00012078899,0.000984873],"domain_scores_gemma":[0.9977526,0.000178839,0.00036717742,0.0010233534,0.00031409136,0.00036394925],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00018888472,0.0016066539,0.003017077,0.00020196804,0.00023104968,0.00005538124,0.0007643945,0.0012466251,0.000036773985],"category_scores_gemma":[0.00017622483,0.0012828484,0.0010239606,0.00037926337,0.0006323764,0.000009310776,0.0007831923,0.00084721524,0.00011624374],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023796075,0.000097679855,1.9673081e-7,0.0046368064,0.0017869397,0.0000059067793,0.0002769256,0.000066215485,0.95185345,0.000656304,0.021151463,0.019230155],"study_design_scores_gemma":[0.00045784024,0.00092684047,0.0000046321506,0.0018227595,0.00077603187,0.00005481931,0.00019984366,0.00013963957,0.23955923,0.000688557,0.7539387,0.0014311416],"about_ca_topic_score_codex":0.000011300387,"about_ca_topic_score_gemma":0.000013117949,"teacher_disagreement_score":0.7327872,"about_ca_system_score_codex":0.00008248449,"about_ca_system_score_gemma":0.00038137738,"threshold_uncertainty_score":0.9996681},"labels":[],"label_agreement":null},{"id":"W4400869843","doi":"10.1038/s41587-024-02324-x","title":"Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"NIH Office of the Director; National Cancer Institute; National Center of Competence in Research Quantum Science and Technology; National Heart, Lung, and Blood Institute; Dana-Farber Cancer Institute; National Human Genome Research Institute; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Massachusetts General Hospital; Natural Sciences and Engineering Research Council of Canada; Friedreich's Ataxia Research Alliance; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Molecular Biology Organization; National Science Foundation","keywords":"Genome editing; DNA polymerase; Polymerase; DNA; Endonuclease; Computational biology; Biology; Genome; Genetics; Computer science; Gene","score_opus":0.004968588236900854,"score_gpt":0.28583238423750895,"score_spread":0.2808637960006081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400869843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90067184,0.09467657,0.003078427,0.000578918,0.00037801583,0.0001703486,0.000029884646,0.00024699248,0.0001690003],"genre_scores_gemma":[0.99338865,0.0009136156,0.0046101008,0.00011972952,0.00076812564,0.0000104126275,0.00004652224,0.00004507918,0.00009774605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988337,0.000014857583,0.00018103926,0.00049818645,0.00008088004,0.00039134367],"domain_scores_gemma":[0.9996224,0.000018867684,0.000031330608,0.00024295697,0.000026787844,0.00005763348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011342814,0.00019741211,0.00015726117,0.00015681228,0.000112804904,0.000078735204,0.00014520282,0.0008629177,0.000010343812],"category_scores_gemma":[0.00010397661,0.00019406748,0.00006286166,0.00020426167,0.00012729083,0.000006236039,0.0002030814,0.00043153984,0.0000025411593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006828999,0.000011969506,0.00016341973,0.00009922188,0.000053825202,0.000031600135,0.000012126396,0.00003436216,0.97737604,0.00082974456,0.00012238973,0.021258468],"study_design_scores_gemma":[0.00015097455,0.00012420409,0.00010726239,0.00006826417,0.000035961617,0.0003315678,0.00015578327,0.000880513,0.86417586,0.00007541283,0.13365716,0.00023706887],"about_ca_topic_score_codex":0.00001688679,"about_ca_topic_score_gemma":0.000011910491,"teacher_disagreement_score":0.13353477,"about_ca_system_score_codex":0.000014201344,"about_ca_system_score_gemma":0.00003674071,"threshold_uncertainty_score":0.7913843},"labels":[],"label_agreement":null},{"id":"W4400880468","doi":"10.1021/cen-10222-scicon6","title":"Breaking up the CRISPR conga line","year":2024,"lang":"en","type":"article","venue":"C&EN Global Enterprise","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Line (geometry); Biology; Genetics; Mathematics; Gene","score_opus":0.005288698552441454,"score_gpt":0.319119888483628,"score_spread":0.3138311899311865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400880468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7112808,0.032246884,0.23467,0.0025678766,0.0053498205,0.0004520199,0.0001828403,0.00021953702,0.013030167],"genre_scores_gemma":[0.99776757,0.00023266528,0.00015327356,0.00032705744,0.0004878414,0.000012737731,0.000034038603,0.000016913482,0.0009679207],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992412,0.000025807198,0.00014138989,0.00027241244,0.00009927903,0.00021994735],"domain_scores_gemma":[0.999583,0.000013627456,0.00001379832,0.00030011692,0.000026189173,0.00006328214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012231644,0.00014117072,0.000085538195,0.000013602776,0.000049029746,0.00008237805,0.00022739537,0.000087637076,0.000035701014],"category_scores_gemma":[0.000045212702,0.00010457087,0.00011264044,0.000096979966,0.000041241823,0.0000027020774,0.00015962045,0.000094312236,0.00004835259],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036980162,0.00019921525,0.008296539,0.00057214603,0.0011240111,0.0002802828,0.0014953166,0.007892923,0.51167566,0.007937208,0.24592486,0.21423204],"study_design_scores_gemma":[0.00048052438,0.00019159597,0.0021546911,0.00013058333,0.000094280964,0.00024154715,0.00027074895,0.0054712133,0.076176606,0.0002785514,0.914094,0.00041567083],"about_ca_topic_score_codex":0.000022452597,"about_ca_topic_score_gemma":0.000022541615,"teacher_disagreement_score":0.66816914,"about_ca_system_score_codex":0.000023752465,"about_ca_system_score_gemma":0.00003873408,"threshold_uncertainty_score":0.42642763},"labels":[],"label_agreement":null},{"id":"W4400917567","doi":"10.21203/rs.3.rs-4656362/v1","title":"A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"CRISPR; Pseudomonas putida; Genome editing; Plasmid; Cas9; Biology; Computer science; Computational biology; Genetics; DNA; Gene","score_opus":0.03873205869155865,"score_gpt":0.3836691876549729,"score_spread":0.3449371289634142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400917567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8273483,0.07806583,0.06583921,0.0020713273,0.0039841137,0.010425078,0.0037734418,0.0003699441,0.008122784],"genre_scores_gemma":[0.99294424,0.0001584606,0.0021228902,0.000028558752,0.0017134715,0.0013038629,0.001064464,0.00014651235,0.00051751273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99611104,0.00028804294,0.0005734517,0.001308675,0.0006287537,0.0010900175],"domain_scores_gemma":[0.99805933,0.00018567672,0.00009155809,0.00083758275,0.00059032685,0.00023555111],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001678044,0.0004828179,0.0005033105,0.00055451435,0.00017539026,0.00033038258,0.0005561488,0.00066599227,0.000020737883],"category_scores_gemma":[0.00040695412,0.00049582345,0.00035406667,0.00036481718,0.00011424253,0.0000047464214,0.0010827208,0.0012523523,0.000034141878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006193519,0.00039503712,0.0006741651,0.029356021,0.0004525073,0.00035021745,0.0010446848,0.07925781,0.87389195,0.0005225452,0.0071478602,0.00628784],"study_design_scores_gemma":[0.0024846625,0.0018418543,0.000316265,0.0065566096,0.00009577364,0.00006444731,0.0031754128,0.04816023,0.8540548,0.0006882495,0.08090964,0.0016520371],"about_ca_topic_score_codex":0.00010972224,"about_ca_topic_score_gemma":0.00011653235,"teacher_disagreement_score":0.165596,"about_ca_system_score_codex":0.00036193946,"about_ca_system_score_gemma":0.0005781881,"threshold_uncertainty_score":0.99974936},"labels":[],"label_agreement":null},{"id":"W4400940900","doi":"10.1101/2024.07.23.604809","title":"Mechanism-guided engineering of a minimal biological particle for genome editing","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; Parker Institute for Cancer Immunotherapy; Alexander von Humboldt-Stiftung","keywords":"Genome editing; Genome; Mechanism (biology); Computational biology; Genome engineering; Biology; Computer science; Evolutionary biology; Genetics; Philosophy; Gene; Epistemology","score_opus":0.01514862146696396,"score_gpt":0.2546073210796872,"score_spread":0.23945869961272323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400940900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95710665,0.002905366,0.037940532,0.000060246362,0.0009703196,0.0005578263,0.00033562173,0.00012088059,0.0000025686056],"genre_scores_gemma":[0.9822098,0.00013189533,0.016051693,0.000032566677,0.0011968003,0.00025780752,0.0000022104152,0.00011283712,0.000004404827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808615,0.000022889246,0.0004981179,0.0007650679,0.00014584987,0.00048191837],"domain_scores_gemma":[0.99885,0.000025592346,0.00014194743,0.00061338546,0.0002127988,0.0001562885],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004150797,0.0003995214,0.00040839973,0.00009268088,0.000041899537,0.000055727527,0.00033756415,0.0005067688,0.000008520056],"category_scores_gemma":[0.00028363054,0.00042098126,0.00025777964,0.00014814179,0.00004327372,0.0000026369987,0.00065842766,0.00028023,0.0000062475915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018571178,0.00003534197,0.0001393969,0.000602661,0.00016447504,0.000006646377,0.0000057602674,0.0014411733,0.9967496,0.00074875116,0.000086544715,0.0000010979868],"study_design_scores_gemma":[0.00028468526,0.00015618227,0.0016183748,0.00014668805,0.00008655611,5.548465e-8,0.0000034743018,0.004416474,0.9905444,0.00000707435,0.0022841801,0.00045187425],"about_ca_topic_score_codex":0.0000045542806,"about_ca_topic_score_gemma":3.943899e-7,"teacher_disagreement_score":0.025103148,"about_ca_system_score_codex":0.00003982757,"about_ca_system_score_gemma":0.000148765,"threshold_uncertainty_score":0.9998242},"labels":[],"label_agreement":null},{"id":"W4401036995","doi":"10.5376/ijmz.2024.14.0008","title":"Application of CRISPR Technology in Endangered Species Conservation","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Zoology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Endangered species; CRISPR; Genome editing; Adaptability; Biology; Biodiversity; Ecology; Gene; Genetics","score_opus":0.0050653548304538925,"score_gpt":0.29653620766079364,"score_spread":0.29147085283033974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401036995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6637328,0.0030754963,0.33042285,0.0021013648,0.0004428353,0.000047410933,0.0000055171486,0.000004650062,0.00016703291],"genre_scores_gemma":[0.9975022,0.00023267748,0.001992942,0.00008709002,0.00011738826,0.0000042753168,0.000016109845,0.000009845445,0.000037447226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932367,0.000021624563,0.00032999556,0.00011416508,0.00012920125,0.000081328646],"domain_scores_gemma":[0.9995534,0.000015024828,0.00009609035,0.00009578397,0.0002215233,0.00001821337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015640816,0.000069226146,0.000114872026,0.00035962038,0.000004342962,0.000008520279,0.00022750141,0.00011181696,0.0000107296955],"category_scores_gemma":[0.0001090902,0.00006931105,0.000071413684,0.00012250514,0.00005798297,0.0000044581125,0.000050085422,0.00010547342,0.0000020273196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046087447,0.00002831044,0.007032445,0.000012377943,0.00009835352,0.000069662216,0.000036737685,0.0011668153,0.98091155,0.0036884593,0.00015462618,0.006754581],"study_design_scores_gemma":[0.00034276524,0.00016104862,0.010539218,0.000040673916,0.000014561661,0.00026625267,0.00006367161,0.00089053414,0.97202,0.002152304,0.013433618,0.000075391756],"about_ca_topic_score_codex":0.0000102362865,"about_ca_topic_score_gemma":0.000017078688,"teacher_disagreement_score":0.33376938,"about_ca_system_score_codex":0.000023874854,"about_ca_system_score_gemma":0.000060314054,"threshold_uncertainty_score":0.28264225},"labels":[],"label_agreement":null},{"id":"W4401052048","doi":"10.1007/978-3-031-63917-3_6","title":"What’s Next for Gene Editing in Agrifood?","year":2024,"lang":"en","type":"book-chapter","venue":"SpringerBriefs in environmental science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Sustainability; Climate change; Stakeholder; Writ; Corporate governance; Political science; Biology; Ecology; Economics; Public relations; Management","score_opus":0.009003717699865155,"score_gpt":0.25635639380964903,"score_spread":0.24735267610978387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401052048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7129191,0.09581552,0.0029152252,0.00064981746,0.015282594,0.00410535,0.00026573392,0.00010884864,0.16793782],"genre_scores_gemma":[0.9200657,0.006334886,0.0017323793,0.00014441182,0.0010047815,0.000075522556,0.00008757533,0.00010480595,0.07044995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829644,0.0000024314934,0.00027852808,0.0007750699,0.00024512756,0.00040238796],"domain_scores_gemma":[0.9995314,0.000009020251,0.000050911243,0.00031954874,0.000003898733,0.0000852119],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000348789,0.00025632017,0.00017720251,0.0001486442,0.000048934755,0.00012710365,0.00035806114,0.00019993442,0.00003469933],"category_scores_gemma":[0.000016563588,0.0002844988,0.000091324146,0.000046512687,0.0003072535,0.000023710989,0.0003954456,0.00021065956,0.00002716578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015500762,0.000027427981,0.00018202937,0.00007795084,0.000014158017,0.000026378773,0.00014012083,0.0017107326,0.9774435,0.001650909,0.00007166177,0.018639628],"study_design_scores_gemma":[0.0007652743,0.00034115257,0.002861663,0.0007866917,0.00003372843,0.000047675072,0.00038949098,0.001053265,0.52642846,0.0028483958,0.46309784,0.0013463402],"about_ca_topic_score_codex":0.0000072602825,"about_ca_topic_score_gemma":0.000060343264,"teacher_disagreement_score":0.4630262,"about_ca_system_score_codex":0.00016444159,"about_ca_system_score_gemma":0.0000407739,"threshold_uncertainty_score":0.9999607},"labels":[],"label_agreement":null},{"id":"W4401052082","doi":"10.1007/978-3-031-63917-3_3","title":"How Are Gene Editing Technologies Regulated in the Agrifood System?","year":2024,"lang":"en","type":"book-chapter","venue":"SpringerBriefs in environmental science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Genome editing; Computational biology; Gene; Biology; Computer science; Genetics; CRISPR","score_opus":0.005106407936934585,"score_gpt":0.21002956750132623,"score_spread":0.20492315956439164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401052082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7374511,0.056699503,0.0009441266,0.0032700486,0.0034840584,0.0030522326,0.00028632226,0.00043783867,0.1943748],"genre_scores_gemma":[0.98845524,0.00041515726,0.00021254664,0.000020130576,0.00021825853,0.000025244519,0.000016847967,0.00003322249,0.010603371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983491,0.000006595927,0.0002147688,0.0006943515,0.00037341463,0.00036180724],"domain_scores_gemma":[0.99932724,0.000007347244,0.000085102,0.0005445927,0.0000040302325,0.000031678148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039982068,0.00027272967,0.00018118112,0.00015888303,0.000077162695,0.000102531485,0.000715507,0.00026813793,0.0000032846133],"category_scores_gemma":[0.000024547131,0.00022382074,0.000070699076,0.000101757345,0.0005537923,0.000007456508,0.00053064065,0.00036131756,0.000012732858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010264042,0.00003450329,0.0009317656,0.00020881605,0.000029957322,0.0002617092,0.00019489652,0.0011356033,0.9846468,0.005144413,0.00014298999,0.0072582997],"study_design_scores_gemma":[0.000660118,0.00031504914,0.012251336,0.0017800684,0.000070496484,0.00042179783,0.005540524,0.0007173196,0.76850706,0.0014452214,0.20647207,0.001818962],"about_ca_topic_score_codex":0.0000058198207,"about_ca_topic_score_gemma":0.000029012628,"teacher_disagreement_score":0.25100416,"about_ca_system_score_codex":0.00017814206,"about_ca_system_score_gemma":0.000020476135,"threshold_uncertainty_score":0.9127145},"labels":[],"label_agreement":null},{"id":"W4401052174","doi":"10.1007/978-3-031-63917-3","title":"International Regulation of Gene Editing Technologies in Crops","year":2024,"lang":"en","type":"book","venue":"SpringerBriefs in environmental science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Saskatchewan Wheat Development Commission; Genome Prairie; National Academies of Sciences, Engineering, and Medicine; Alberta Wheat Commission; Canadian Food Inspection Agency; Philippine Rice Research Institute; Genome Canada; European Food Safety Authority; Western Grains Research Foundation; World Health Organization; European Commission; Ministry of Agriculture - Saskatchewan; Agriculture and Agri-Food Canada; National Science Foundation","keywords":"Genome editing; Biology; Gene; Biotechnology; Computer science; Genetics; CRISPR","score_opus":0.003973186604753075,"score_gpt":0.24175746081085644,"score_spread":0.23778427420610337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401052174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7595933,0.00933145,0.002238307,0.00026169486,0.0030596927,0.000807883,0.00013770109,0.000086298445,0.22448367],"genre_scores_gemma":[0.9838278,0.0005164881,0.0016585448,0.000005967196,0.00014444586,0.000010990795,0.000045127712,0.000019906358,0.01377071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998872,0.0000038224102,0.00024493603,0.00042998404,0.00026597132,0.00018331407],"domain_scores_gemma":[0.9996732,0.0000043251252,0.0000643588,0.0002355008,0.0000042950414,0.000018320243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025167206,0.00013499426,0.00011530269,0.00022474094,0.000017030725,0.000015949481,0.00039159734,0.0001611228,0.00002076305],"category_scores_gemma":[0.00003719296,0.00014892415,0.00003997136,0.00009505061,0.00042576672,0.000006469923,0.00040582503,0.00016735912,0.0000067258534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000046725268,0.000017608661,0.0021449795,0.000026705166,0.000005643352,0.0000060502252,0.00005248923,0.002121041,0.9863627,0.00011603039,0.00010760369,0.009034489],"study_design_scores_gemma":[0.0001966036,0.00005777653,0.021336956,0.00023799694,0.0000063159982,0.000014087888,0.00012222693,0.0007377259,0.92194504,0.00057387934,0.054478858,0.00029253002],"about_ca_topic_score_codex":0.0000070139013,"about_ca_topic_score_gemma":0.000017909664,"teacher_disagreement_score":0.22423452,"about_ca_system_score_codex":0.00021052643,"about_ca_system_score_gemma":0.00005276806,"threshold_uncertainty_score":0.6072951},"labels":[],"label_agreement":null},{"id":"W4401053391","doi":"10.1007/978-3-031-63917-3_1","title":"Introduction: Why Study the Governance of Gene Edited Agrifoods?","year":2024,"lang":"en","type":"book-chapter","venue":"SpringerBriefs in environmental science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Pace; Corporate governance; Politics; Supply chain; Political science; Business; Economics; Geography; Management; Marketing","score_opus":0.004911163994338647,"score_gpt":0.23086930512305318,"score_spread":0.22595814112871454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401053391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7750504,0.034527738,0.0009669723,0.0018742973,0.008690753,0.0031152961,0.00028692838,0.00006616725,0.17542146],"genre_scores_gemma":[0.9471943,0.0009756043,0.00018517386,0.000052851043,0.0013349168,0.000017193846,0.000013771093,0.000039035604,0.050187185],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984594,0.000005837002,0.00026225153,0.00062937196,0.00042865425,0.0002145005],"domain_scores_gemma":[0.99926186,0.0000054975694,0.00008769414,0.00059056043,0.000006812728,0.000047594516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033853512,0.00021430409,0.0001569141,0.000046231173,0.00006094149,0.000023481325,0.0005021808,0.00009649841,0.00010781145],"category_scores_gemma":[0.000015499607,0.00017652864,0.00007104043,0.00007253444,0.0006057866,0.0000052439764,0.00040946537,0.00022052987,0.00002352509],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003426416,0.00014449983,0.0005925169,0.000039693874,0.00009309037,0.000021469834,0.0003842112,0.0025689208,0.98803735,0.0024779632,0.001561625,0.0040443866],"study_design_scores_gemma":[0.00035825666,0.0005584467,0.01546347,0.00006846334,0.00007386894,0.00004158774,0.00023617956,0.00008102089,0.32391474,0.000317824,0.65826803,0.0006180985],"about_ca_topic_score_codex":0.000012815106,"about_ca_topic_score_gemma":0.000031003914,"teacher_disagreement_score":0.66412264,"about_ca_system_score_codex":0.000086602304,"about_ca_system_score_gemma":0.000030361767,"threshold_uncertainty_score":0.7198629},"labels":[],"label_agreement":null},{"id":"W4401053682","doi":"10.1007/978-3-031-63917-3_2","title":"What Is Gene Editing?","year":2024,"lang":"en","type":"book-chapter","venue":"SpringerBriefs in environmental science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Computer science; Computational biology; Biology; Genetics","score_opus":0.004828649772721672,"score_gpt":0.24348471423580914,"score_spread":0.23865606446308746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401053682","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23310079,0.10643176,0.00086220674,0.00083322317,0.013424105,0.0014795068,0.00026833295,0.00013158098,0.6434685],"genre_scores_gemma":[0.56784606,0.0129998205,0.0007608395,0.00049574475,0.0012237347,0.000020070445,0.00005938176,0.00012361362,0.41647074],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981935,0.0000020697544,0.0002268717,0.00083747087,0.00038234965,0.00035771637],"domain_scores_gemma":[0.9993548,0.000003334997,0.000048039365,0.00047174533,0.0000040713057,0.00011801462],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022173114,0.00028151236,0.00015681966,0.00011307305,0.00006336369,0.00011260508,0.00041863657,0.00020078778,0.00023096196],"category_scores_gemma":[0.000005231331,0.0003048419,0.0000979183,0.000040092367,0.0005194723,0.000013442256,0.0006252052,0.00023884569,0.0002092032],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008987225,0.000026777732,0.00023305276,0.000055078966,0.00003266699,0.00006787283,0.00021820524,0.0003598215,0.98091465,0.0015077735,0.0005995251,0.015975568],"study_design_scores_gemma":[0.00014978327,0.00009738741,0.00063198444,0.00022206195,0.000020864978,0.00004300797,0.000058994196,0.00010943337,0.46119964,0.0011344813,0.5357445,0.00058787595],"about_ca_topic_score_codex":0.000004257568,"about_ca_topic_score_gemma":0.000008321566,"teacher_disagreement_score":0.535145,"about_ca_system_score_codex":0.00012537191,"about_ca_system_score_gemma":0.000037097172,"threshold_uncertainty_score":0.9999404},"labels":[],"label_agreement":null},{"id":"W4401053693","doi":"10.1007/978-3-031-63917-3_4","title":"Novel Genomic Techniques and Applications on the Horizon","year":2024,"lang":"en","type":"book-chapter","venue":"SpringerBriefs in environmental science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"CRISPR; Genome editing; Pipeline (software); Computer science; Cas9; Emerging technologies; Sustainability; Biology; Gene; Operating system; Genetics; Ecology; Artificial intelligence","score_opus":0.005702088016728166,"score_gpt":0.2360382414832685,"score_spread":0.23033615346654032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401053693","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08884343,0.013288261,0.0037727377,0.0004681734,0.0003922068,0.002240375,0.00018019057,0.00008086896,0.8907338],"genre_scores_gemma":[0.92136824,0.004049785,0.0010390811,0.0001415311,0.0005150778,0.00014638413,0.000020556558,0.000073774354,0.07264558],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99912363,0.0000012956325,0.00011392421,0.00046031576,0.00014549388,0.0001553408],"domain_scores_gemma":[0.9995916,0.0000067890346,0.00002697216,0.00032819377,0.0000016231678,0.000044804237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001650863,0.00015841718,0.00007554261,0.000058286772,0.00007615298,0.00003207211,0.00026077783,0.000097132615,0.000018648208],"category_scores_gemma":[0.0000025122838,0.0001308315,0.000032902844,0.000023850103,0.00049524143,0.0000019453898,0.00035015531,0.00017164221,0.000026113901],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003283695,0.000011537522,0.000022596487,0.000011416217,0.00000666565,0.000002292044,0.0000145205495,0.000039307623,0.95320004,0.025609603,0.000024305018,0.021054443],"study_design_scores_gemma":[0.00006347881,0.00016042638,0.0006447494,0.00006861648,0.000012191404,0.000034590565,0.00001577857,0.00002886681,0.22049019,0.001388093,0.7767695,0.00032349312],"about_ca_topic_score_codex":0.0000037273903,"about_ca_topic_score_gemma":0.0000052755963,"teacher_disagreement_score":0.8325248,"about_ca_system_score_codex":0.00006808521,"about_ca_system_score_gemma":0.000016890546,"threshold_uncertainty_score":0.53351533},"labels":[],"label_agreement":null},{"id":"W4401063257","doi":"10.60087/jklst.v3.n4.p11","title":"Precision Gene Editing Strategies with CRISPR-Cas9 for Advancing Cancer Immunotherapy and Alzheimer's Disease","year":2024,"lang":"en","type":"article","venue":"Journal of Knowledge Learning and Science Technology ISSN 2959-6386 (online)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"CRISPR; Genome editing; Disease; Immunotherapy; Computational biology; Cancer; Cancer immunotherapy; Gene; Medicine; Biology; Genetics; Internal medicine","score_opus":0.008782334917357972,"score_gpt":0.35047128729639077,"score_spread":0.3416889523790328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401063257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8401612,0.11947453,0.039132636,0.0007291364,0.0003140858,0.000111040266,0.000007955146,0.000050191393,0.00001924905],"genre_scores_gemma":[0.9845312,0.004855041,0.010026316,0.000016862046,0.0004369194,0.000008559256,0.0000036132749,0.000031769345,0.0000897034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989284,0.000018330413,0.00026438324,0.00033935838,0.00013331424,0.00031620622],"domain_scores_gemma":[0.99931514,0.00004645763,0.000110808796,0.00012103298,0.0002766445,0.00012989943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004914461,0.00017302703,0.00020499989,0.00041425985,0.000228009,0.000113258524,0.00020851733,0.00011314423,0.0000022320007],"category_scores_gemma":[0.00020460236,0.00013211116,0.000051568863,0.00040504,0.0004138464,0.000038807757,0.000092462564,0.00033805278,1.8093802e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001404911,0.00006037504,0.0060543455,0.00009588958,0.00012035198,0.000024141991,0.00041682177,0.003899638,0.74417704,0.00011475818,0.00013107773,0.24476509],"study_design_scores_gemma":[0.0045275656,0.007347143,0.015910454,0.0034353475,0.0008307009,0.0020356434,0.0192427,0.10421925,0.5320941,0.0021489605,0.30626813,0.0019399739],"about_ca_topic_score_codex":0.0000025333445,"about_ca_topic_score_gemma":0.000022585056,"teacher_disagreement_score":0.30613706,"about_ca_system_score_codex":0.00001985962,"about_ca_system_score_gemma":0.000375918,"threshold_uncertainty_score":0.53873366},"labels":[],"label_agreement":null},{"id":"W4401074160","doi":"10.1021/cen-10223-buscon1","title":"Agilent to acquire BioVectra for nearly $1 billion","year":2024,"lang":"en","type":"article","venue":"C&EN Global Enterprise","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Oligonucleotide; CRISPR; Business; Guide RNA; Genome editing; Biology; Gene; Genetics","score_opus":0.004656947133591036,"score_gpt":0.32372046561131146,"score_spread":0.3190635184777204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401074160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64276993,0.0060686846,0.3467502,0.0008085163,0.0015093616,0.00053160515,0.00025162695,0.00009583673,0.0012142416],"genre_scores_gemma":[0.9965718,0.0001153553,0.0018450727,0.0003218783,0.00042910717,0.0000551248,0.0000696022,0.00002136244,0.00057070423],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999194,0.000009834434,0.00012937162,0.00034209277,0.000078767305,0.0002459087],"domain_scores_gemma":[0.9996104,0.0000074129935,0.000008970665,0.0002226744,0.000028741202,0.000121749355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007991728,0.00013921966,0.00009176903,0.000028667919,0.000029095296,0.00006650191,0.00015008592,0.00009467593,0.000013459346],"category_scores_gemma":[0.000036826645,0.00012907013,0.00013011353,0.00011014974,0.000013414542,0.0000029457924,0.000089134985,0.0000338771,0.000048725302],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025854187,0.00009616176,0.000741873,0.00025029533,0.0002115869,0.000026091893,0.00029718704,0.002917743,0.79877424,0.000662816,0.08262532,0.11313811],"study_design_scores_gemma":[0.00040266066,0.00066668773,0.0012530953,0.00011764425,0.000047493704,0.000036483565,0.000065675944,0.0022973348,0.14555217,0.00017055607,0.8490122,0.00037803012],"about_ca_topic_score_codex":0.00001202718,"about_ca_topic_score_gemma":0.000009920188,"teacher_disagreement_score":0.76638687,"about_ca_system_score_codex":0.000040497445,"about_ca_system_score_gemma":0.000035475743,"threshold_uncertainty_score":0.52633274},"labels":[],"label_agreement":null},{"id":"W4401212766","doi":"10.1089/cmb.2023.0331","title":"A Rigorous Framework to Classify the Postduplication Fate of Paralogous Genes","year":2024,"lang":"en","type":"article","venue":"Journal of Computational Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Agence Nationale de la Recherche","keywords":"Biology; Gene; Computational biology; Genetics; Computer science; Evolutionary biology","score_opus":0.009343085250732642,"score_gpt":0.3580712821803014,"score_spread":0.34872819692956875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401212766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5174068,0.0051525724,0.47543052,0.0015507326,0.00034489777,0.00005773609,0.000010508398,0.0000034897123,0.000042697102],"genre_scores_gemma":[0.9868655,0.0001417715,0.012335606,0.00023869403,0.00037182635,0.0000028411846,0.000016078766,0.000007450678,0.000020213502],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994377,0.000036591515,0.000268429,0.000097222604,0.000072343544,0.0000877142],"domain_scores_gemma":[0.9995454,0.00010041425,0.00007751909,0.000086150736,0.00015300873,0.000037512462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001801518,0.000068471665,0.00010686985,0.000063852065,0.000023303466,0.000011489237,0.00014787423,0.00008396443,0.000007381384],"category_scores_gemma":[0.00006749229,0.000045913945,0.00008664648,0.00009934603,0.000042709853,0.000001825751,0.000034549,0.00009601715,0.0000052811083],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014796709,0.00005265434,0.0015047119,0.00004528752,0.00032320077,0.000008408855,0.00028008025,0.27456155,0.6431144,0.0123821525,0.0027292722,0.0648503],"study_design_scores_gemma":[0.0012059418,0.006341253,0.09381924,0.00036828665,0.00027585472,0.00253633,0.0003386319,0.022262743,0.32612693,0.15398702,0.39183947,0.0008982983],"about_ca_topic_score_codex":0.0000020187379,"about_ca_topic_score_gemma":0.0000011621947,"teacher_disagreement_score":0.46945867,"about_ca_system_score_codex":0.00000779313,"about_ca_system_score_gemma":0.00007286251,"threshold_uncertainty_score":0.18723163},"labels":[],"label_agreement":null},{"id":"W4401240302","doi":"10.1016/j.aca.2024.343048","title":"Dual amplification dynamic DNA network system for CRISPR/Cas12a based p53 gene detection","year":2024,"lang":"en","type":"article","venue":"Analytica Chimica Acta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; CRISPR; DNA; Dual (grammatical number); Gene; Computational biology; Biochemistry","score_opus":0.007246379563744832,"score_gpt":0.2811548866325908,"score_spread":0.27390850706884595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401240302","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4233025,0.0005629896,0.5722966,0.0007970181,0.001325169,0.0007420372,0.00011098366,0.00025806463,0.0006046141],"genre_scores_gemma":[0.9964504,0.000044892866,0.0021390014,0.000074731586,0.00065266393,0.00006924154,0.000339677,0.000051432224,0.00017792915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988337,0.000023985554,0.0002503636,0.00046862272,0.00010832757,0.00031500633],"domain_scores_gemma":[0.99937564,0.000038945007,0.000039890398,0.00039457076,0.00006172915,0.000089240384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019090419,0.00018915108,0.00015775276,0.0000748102,0.00010160662,0.00008180253,0.0001265588,0.0001627187,0.0000076790975],"category_scores_gemma":[0.000042085627,0.00018874898,0.00018011987,0.00018804293,0.000026742468,0.0000045949937,0.000034437802,0.00009024752,0.000012276253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004526385,0.000015966056,0.000012535,0.00015622204,0.000110082074,0.0000016331435,0.000010019228,0.00073333655,0.9964469,0.000099781275,0.0012603719,0.0011078932],"study_design_scores_gemma":[0.00028382533,0.00017240782,0.0005661421,0.000058397593,0.00020021871,0.00003144124,0.000031112733,0.33786127,0.639306,0.000050683775,0.021140972,0.00029751362],"about_ca_topic_score_codex":0.000003093168,"about_ca_topic_score_gemma":0.000031873602,"teacher_disagreement_score":0.57314795,"about_ca_system_score_codex":0.000054579737,"about_ca_system_score_gemma":0.000059479862,"threshold_uncertainty_score":0.76969594},"labels":[],"label_agreement":null},{"id":"W4401276537","doi":"10.5376/mpb.2024.15.0009","title":"Precision Editing: Revolutionary Applications of Genome Editing Technology in Tree Breeding","year":2024,"lang":"en","type":"article","venue":"Molecular Plant Breeding","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Genome editing; Genome; Tree (set theory); Computational biology; Evolutionary biology; Genetics; Gene","score_opus":0.007137282447151604,"score_gpt":0.25597165097577007,"score_spread":0.24883436852861845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401276537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5222493,0.02412656,0.44838387,0.00064044463,0.00064573606,0.000621575,0.00013946583,0.00015712046,0.003035966],"genre_scores_gemma":[0.99534565,0.00020602571,0.0034910084,0.000017590339,0.00058313226,0.00007213005,0.00019048099,0.00003567485,0.000058276273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987218,0.000014437397,0.0003558598,0.00043017155,0.00017799727,0.00029977912],"domain_scores_gemma":[0.9995859,0.000022108485,0.00005653353,0.00023366927,0.000049764556,0.00005196801],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029147233,0.00016902096,0.00017639503,0.00042605313,0.000049898365,0.000017257535,0.00023433761,0.00020912131,0.000006873461],"category_scores_gemma":[0.00008826667,0.00018748669,0.000086594846,0.00050233543,0.000051426632,0.0000072955777,0.0001846554,0.00019998802,0.0000047414032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000069755415,0.00001817726,0.0006595602,0.00011265574,0.000029729827,0.000030985706,0.00004476304,0.0017640023,0.98895526,0.0008661455,0.0002941522,0.0072176084],"study_design_scores_gemma":[0.00054554985,0.00036282145,0.0013316143,0.0007350895,0.00006233823,0.0005050566,0.000649276,0.014719401,0.94287556,0.0013374351,0.036300767,0.00057506637],"about_ca_topic_score_codex":0.000009862653,"about_ca_topic_score_gemma":0.0000104772225,"teacher_disagreement_score":0.4730964,"about_ca_system_score_codex":0.00003859528,"about_ca_system_score_gemma":0.00003687038,"threshold_uncertainty_score":0.76454854},"labels":[],"label_agreement":null},{"id":"W4401304889","doi":"10.1016/j.bios.2024.116631","title":"Hydrophilic/hydrophobic modified microchip for detecting multiple gene doping candidates using CRISPR-Cas12a and RPA","year":2024,"lang":"en","type":"article","venue":"Biosensors and Bioelectronics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Natural Science Foundation of Hubei Province; China Postdoctoral Science Foundation; World Anti-Doping Agency; National Natural Science Foundation of China","keywords":"CRISPR; Context (archaeology); Software portability; Multiplexing; Nanotechnology; Multiplex; Computational biology; Cas9; Microfluidics; Lab-on-a-chip; Plasmid; Computer science; Gene; Materials science; Bioinformatics; Biology; Genetics; Telecommunications","score_opus":0.012231751002854351,"score_gpt":0.29095229796462385,"score_spread":0.2787205469617695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401304889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9574431,0.028169328,0.013806208,0.00006664501,0.00015517206,0.00026904378,0.000041449006,0.000038313272,0.000010693519],"genre_scores_gemma":[0.99458194,0.0019734171,0.0028914197,0.00005103843,0.00031651664,0.000012559614,0.00004262187,0.00004933691,0.00008118132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876136,0.00001726624,0.00020231302,0.00050727115,0.000063704276,0.00044811805],"domain_scores_gemma":[0.99963796,0.00003675247,0.000032625954,0.00016669692,0.000031416293,0.00009452162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001390178,0.0002367866,0.00017642825,0.00008552502,0.00018332603,0.00011114082,0.000071201684,0.00016952837,9.319217e-7],"category_scores_gemma":[0.000037061815,0.0002224215,0.000079820595,0.00010144805,0.00005909211,0.0000054663474,0.000075412725,0.00011396927,5.547126e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004793047,0.000008258545,0.0001478633,0.00013433142,0.000063884916,0.000003389918,0.000058874084,0.00043938842,0.99582005,0.000027708991,0.00003491973,0.0032134214],"study_design_scores_gemma":[0.00040027665,0.0002709888,0.000051147614,0.000039915427,0.00005572556,0.00013131181,0.00003929041,0.13464496,0.8595925,0.000066505614,0.004403189,0.0003041747],"about_ca_topic_score_codex":0.00005664069,"about_ca_topic_score_gemma":0.00007531858,"teacher_disagreement_score":0.1362275,"about_ca_system_score_codex":0.000027185759,"about_ca_system_score_gemma":0.000056581965,"threshold_uncertainty_score":0.9070085},"labels":[],"label_agreement":null},{"id":"W4401345763","doi":"10.1186/s12943-024-02048-1","title":"BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance","year":2024,"lang":"en","type":"letter","venue":"Molecular Cancer","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Health and Medical Research Council; National Cancer Institute; Medical Research Council; Clovis Oncology; QIMR Berghofer Medical Research Institute","keywords":"Biology; PARP inhibitor; Exon skipping; Exon; Genetics; splice; Splice site mutation; Mutation; Cancer research; Poly ADP ribose polymerase; Molecular biology; Alternative splicing; DNA; Gene; Polymerase","score_opus":0.005198736292683934,"score_gpt":0.2665901694575058,"score_spread":0.2613914331648219,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401345763","genre_codex":"review","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14955711,0.47267988,0.028405292,0.32983935,0.0049206777,0.0019622175,0.0023643556,0.00029087835,0.00998023],"genre_scores_gemma":[0.20521279,0.01229413,0.0062516136,0.69911015,0.019903729,0.0016062252,0.006951107,0.0011463655,0.047523875],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982101,0.000039335377,0.00028020312,0.0008396488,0.00021632123,0.00041441803],"domain_scores_gemma":[0.9992552,0.000012418237,0.0000782421,0.00049068604,0.00008010014,0.00008335983],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006962317,0.00040536327,0.00028511765,0.00010961049,0.00008047954,0.00008068235,0.00017115862,0.00061447435,0.00005204649],"category_scores_gemma":[0.0000208091,0.00044564003,0.00017310203,0.0001330839,0.00009736477,0.000004280931,0.00018485212,0.0007930686,0.00002197949],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000102144795,0.000005117449,0.000024890545,0.00060391,0.00025231004,0.00039856846,0.00013069142,0.00017739725,0.25108376,0.000008572701,0.7460265,0.0012780585],"study_design_scores_gemma":[0.000234972,0.00003147972,0.00007757291,0.00026810006,0.00014480464,0.00002477931,0.000019743811,0.000040214993,0.09245892,0.0000695058,0.90611887,0.0005110338],"about_ca_topic_score_codex":0.000037528094,"about_ca_topic_score_gemma":0.00020117688,"teacher_disagreement_score":0.46038574,"about_ca_system_score_codex":0.000055978016,"about_ca_system_score_gemma":0.00019368874,"threshold_uncertainty_score":0.99979955},"labels":[],"label_agreement":null},{"id":"W4401441591","doi":"10.1007/s12355-024-01475-0","title":"Cutting-Edge Genome Editing in Sugarcane and Sugar Crops: A Comprehensive Overview","year":2024,"lang":"en","type":"article","venue":"Sugar Tech","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Campbell Scientific (Canada)","funders":"","keywords":"Context (archaeology); Genome editing; Biotechnology; Sustainability; Agriculture; Sugar; Setaria; Biology; Agronomy; Genome; Ecology; Gene","score_opus":0.012487484107610117,"score_gpt":0.30682189010539473,"score_spread":0.2943344059977846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401441591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93463385,0.06252396,0.0012043859,0.00021400112,0.00029737139,0.00019504523,0.000024760051,0.00006075108,0.00084590033],"genre_scores_gemma":[0.9964353,0.0018193219,0.00070948986,0.000105731975,0.00052521145,0.000018525807,0.00005555744,0.000037147474,0.00029373763],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99904126,0.00002119299,0.00019055209,0.0003780814,0.00008825703,0.00028068578],"domain_scores_gemma":[0.99964887,0.00001933375,0.000018209697,0.00021470684,0.00003472326,0.00006417255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012264967,0.00016474903,0.00015739865,0.000088728455,0.00003955106,0.00004871027,0.00010957481,0.00011868707,0.00002292391],"category_scores_gemma":[0.00003735767,0.00016698317,0.000053313444,0.00016113944,0.000047080375,0.0000033407848,0.00015049923,0.00015538745,0.000012912113],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013537839,0.00002544453,0.0027417878,0.000610905,0.00006323409,0.000097179334,0.00034272097,0.00019260623,0.9810691,0.00026824442,0.00089000055,0.013685275],"study_design_scores_gemma":[0.0011444885,0.0004459645,0.04394664,0.0006382976,0.00007116408,0.00034892574,0.00096173934,0.0023811532,0.2078111,0.0004912951,0.7406523,0.0011068833],"about_ca_topic_score_codex":0.000052658295,"about_ca_topic_score_gemma":0.00007433826,"teacher_disagreement_score":0.773258,"about_ca_system_score_codex":0.000017931852,"about_ca_system_score_gemma":0.000035926132,"threshold_uncertainty_score":0.6809376},"labels":[],"label_agreement":null},{"id":"W4401443737","doi":"10.1007/s00253-024-13266-4","title":"CHO cell engineering via targeted integration of circular miR-21 decoy using CRISPR/RMCE hybrid system","year":2024,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Clinical Research Institute","funders":"Pasteur Institute of Iran","keywords":"Chinese hamster ovary cell; Expression cassette; CRISPR; Biology; Cell growth; Recombinant DNA; Cas9; Cell biology; Cell culture; Molecular biology; Gene; Genetics; Vector (molecular biology)","score_opus":0.0033847002976476258,"score_gpt":0.21567389312630605,"score_spread":0.21228919282865844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401443737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.651842,0.008090051,0.339335,0.000041139498,0.00027762193,0.00023583017,0.000034532957,0.000103326405,0.00004053702],"genre_scores_gemma":[0.9941758,0.00022707456,0.0052617546,0.000026540365,0.00007314083,0.000022091206,0.00016248667,0.00003232741,0.000018789435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888164,0.00001536196,0.00029044968,0.0004823202,0.000024920178,0.000305308],"domain_scores_gemma":[0.99958545,0.0000149797615,0.00005361429,0.0002785819,0.000027840246,0.000039535098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013727658,0.0002358304,0.0002668731,0.0001926637,0.000047930265,0.000011273377,0.00015837472,0.00059409277,0.0000052845644],"category_scores_gemma":[0.000010254373,0.00022717283,0.00007223445,0.00015506796,0.00013565023,0.0000029223581,0.00013015624,0.00023495936,0.0000060412226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017828457,0.000014863683,0.000013922052,0.00024290459,0.000073122836,0.0000085777065,0.0000180817,0.0004341632,0.99622566,0.00060413714,0.000089595545,0.0022571485],"study_design_scores_gemma":[0.00023219251,0.00008583864,0.00001896428,0.00004008006,0.000052080966,0.00037673925,0.000071878225,0.0040972233,0.98686796,0.000017423528,0.007911394,0.00022819516],"about_ca_topic_score_codex":0.0000134066895,"about_ca_topic_score_gemma":0.000003224316,"teacher_disagreement_score":0.34233382,"about_ca_system_score_codex":0.000022432843,"about_ca_system_score_gemma":0.000030820545,"threshold_uncertainty_score":0.9263839},"labels":[],"label_agreement":null},{"id":"W4401700582","doi":"10.1080/15265161.2024.2361895","title":"When Gene Editing Should Be Mandatory","year":2024,"lang":"en","type":"letter","venue":"The American Journal of Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto; Western University","funders":"","keywords":"Genome editing; Gene; Computer science; Biology; Genetics; CRISPR","score_opus":0.038926180988255774,"score_gpt":0.35164820488391707,"score_spread":0.3127220238956613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401700582","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012016539,0.008294842,0.0067443247,0.970393,0.00209248,0.000100036836,0.000089151545,0.000015500073,0.0002541242],"genre_scores_gemma":[0.035632856,0.003949711,0.0044676736,0.9100306,0.043812603,0.0000062475137,0.00013318147,0.00021641907,0.0017506815],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99844843,0.00013537145,0.0004385772,0.000229574,0.00043994817,0.00030812318],"domain_scores_gemma":[0.9987484,0.000077122044,0.0004837259,0.0004417911,0.00018243515,0.000066501],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008188811,0.00027473643,0.00038397493,0.000105469284,0.000066906476,0.000067027606,0.0006367904,0.00035349227,0.00001535872],"category_scores_gemma":[0.00010671936,0.00019093697,0.00032969582,0.00010245836,0.0006826242,0.0000022178203,0.0001830712,0.002842058,0.0000076234937],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025768448,0.0000056043323,0.000009747262,0.00006675645,0.00033395973,0.00016427628,0.00023553155,0.0001024463,0.01820497,0.0000050670765,0.9776618,0.0031840724],"study_design_scores_gemma":[0.00009507596,0.00050329656,0.000008373987,0.00010047772,0.0002131831,0.00061618886,0.000272375,0.000019279549,0.028894573,0.00015267047,0.96888965,0.00023485874],"about_ca_topic_score_codex":0.0000263319,"about_ca_topic_score_gemma":0.000005720243,"teacher_disagreement_score":0.060362376,"about_ca_system_score_codex":0.000025694491,"about_ca_system_score_gemma":0.00020739043,"threshold_uncertainty_score":0.99945843},"labels":[],"label_agreement":null},{"id":"W4401715907","doi":"10.1093/nar/gkae682","title":"A CRISPR-dCas13 RNA-editing tool to study alternative splicing","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Regional Development Fund; Laboratoire d'Excellence EpiGenMed; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Institut National Du Cancer; National Institute for Health and Care Research; Ligue Contre le Cancer; Ministerio de Ciencia e Innovación; Centre National de la Recherche Scientifique; Université Paris-Saclay; Queen's University; Queen's University Belfast; State Key Laboratory of Molecular Biology; New York State Department of Health; Sleep Research Society Foundation","keywords":"Biology; RNA splicing; Alternative splicing; Computational biology; CRISPR; Genome editing; Gene; RNA; Intron; Genetics; Context (archaeology); Gene isoform","score_opus":0.03600648179812218,"score_gpt":0.4160998458692274,"score_spread":0.3800933640711052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401715907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98286176,0.00063190144,0.012250235,0.00033581906,0.00033668813,0.00053898594,0.000010769647,0.000051242685,0.0029825969],"genre_scores_gemma":[0.9961988,0.000045909317,0.0011323085,0.000068064095,0.0011960346,0.00009568324,0.000009042395,0.000058461137,0.0011957522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980375,0.00010042718,0.00021226375,0.00059235253,0.000508405,0.00054901495],"domain_scores_gemma":[0.9991987,0.000047310972,0.000010354979,0.0004310595,0.00016238331,0.00015020082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010710232,0.00016084807,0.00013526308,0.00021089615,0.00016758496,0.00018318048,0.00036359555,0.00008652616,0.000108219836],"category_scores_gemma":[0.00031747582,0.00015321845,0.00007071198,0.00043167602,0.00004184228,0.0000062500203,0.0004972849,0.0003738911,0.0002057285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005388032,0.00011091263,0.0011906748,0.00006951779,0.00016293157,0.00014871574,0.0023438537,0.00072876655,0.9066185,0.00017538224,0.0073665604,0.0810303],"study_design_scores_gemma":[0.0007829551,0.0022260484,0.007476998,0.00016867784,0.000030574556,0.000048694106,0.005408969,0.0068814913,0.8823019,0.0002324343,0.093836166,0.0006050639],"about_ca_topic_score_codex":0.000091408445,"about_ca_topic_score_gemma":0.000024509112,"teacher_disagreement_score":0.086469606,"about_ca_system_score_codex":0.000049986716,"about_ca_system_score_gemma":0.000058337762,"threshold_uncertainty_score":0.6248067},"labels":[],"label_agreement":null},{"id":"W4401855593","doi":"10.1093/genetics/iyae139","title":"In vivo dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1","year":2024,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université Laval; Université de Montréal; Centre Hospitalier Universitaire de Sherbrooke; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Fondation du Grand défi Pierre Lavoie; Banting Research Foundation","keywords":"Biology; CRISPR; Genetics; Tyrosinemia; Gene; In vivo; Genome editing; Tyrosine","score_opus":0.007066912793950162,"score_gpt":0.26715506384527277,"score_spread":0.2600881510513226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401855593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828243,0.013773192,0.0023397508,0.000057395253,0.00069099566,0.00017534748,0.00003275157,0.000018103274,0.00008814201],"genre_scores_gemma":[0.99765867,0.00055219163,0.00040598703,0.000027770142,0.00036787806,0.000011235921,0.000020783065,0.000042079922,0.00091339194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991353,0.000029791856,0.00019792742,0.00028399617,0.00014309527,0.00020989143],"domain_scores_gemma":[0.9994888,0.000012422634,0.00003422029,0.00036240602,0.000064661406,0.000037525093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010544809,0.00016540065,0.00012768107,0.000060668208,0.000046792637,0.000032659565,0.00015585005,0.00011427073,0.0000157463],"category_scores_gemma":[0.000024301593,0.00012461655,0.000058371057,0.00028316185,0.00006049408,0.000005344077,0.00010056654,0.00011505264,0.0000024680487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023462217,0.000022185946,0.0022939893,0.00012396033,0.00003117263,0.0000066823686,0.00018425794,0.011099054,0.9841258,0.000013838581,0.0013635567,0.0007120747],"study_design_scores_gemma":[0.00015687809,0.00010354119,0.0035194133,0.000053360054,0.000026043632,0.000049635455,0.00014476327,0.0009301013,0.98972523,0.000016596347,0.0051120506,0.00016241151],"about_ca_topic_score_codex":0.000056972865,"about_ca_topic_score_gemma":0.0005269971,"teacher_disagreement_score":0.01483436,"about_ca_system_score_codex":0.000014522575,"about_ca_system_score_gemma":0.00006736436,"threshold_uncertainty_score":0.50817156},"labels":[],"label_agreement":null},{"id":"W4401856760","doi":"10.1101/2024.08.23.609401","title":"Dna2 nuclease resolves RNA:DNA hybrids at double-strand breaks","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Nuclease; DNA; Double strand; RNA; Genetics; Biology; Hybrid; Computational biology; DNA damage; Gene; Botany","score_opus":0.00861887958371637,"score_gpt":0.24410884748450906,"score_spread":0.23548996790079268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401856760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851819,0.010348887,0.00089322595,0.0002003038,0.0018933447,0.00057585735,0.0004593444,0.00027447342,0.00017263168],"genre_scores_gemma":[0.9957572,0.0008221221,0.0012606923,0.00014827508,0.001452239,0.00012971272,0.0000051298493,0.00027050448,0.0001541051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99690086,0.000049282335,0.00054012035,0.0014652524,0.00033889175,0.0007055715],"domain_scores_gemma":[0.99755,0.000013699923,0.0001546211,0.0016588812,0.0002014609,0.00042134852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034257298,0.0007557234,0.0005043504,0.00018431214,0.0001498643,0.00023523648,0.00062029995,0.0007610344,0.00006797629],"category_scores_gemma":[0.000053999007,0.000825694,0.00035418983,0.00021493829,0.000141393,0.0000052806613,0.0015793308,0.0006822322,0.00014957781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013915641,0.00006070792,0.00029284757,0.0005916242,0.00028886384,0.00010024809,0.0000075982366,0.00040891016,0.99353886,0.00010401902,0.0044614994,0.000005657924],"study_design_scores_gemma":[0.00079561054,0.00008174497,0.0034199166,0.00027959136,0.00019830052,1.9515974e-7,0.0000021110295,0.00020805311,0.935883,0.0000027690442,0.058168188,0.00096055405],"about_ca_topic_score_codex":0.000037588878,"about_ca_topic_score_gemma":0.000010908369,"teacher_disagreement_score":0.0576559,"about_ca_system_score_codex":0.00012825435,"about_ca_system_score_gemma":0.0003398794,"threshold_uncertainty_score":0.9994194},"labels":[],"label_agreement":null},{"id":"W4401868077","doi":"10.1021/jacs.4c02354","title":"RNA-Activated CRISPR/Cas12a Nanorobots Operating in Living Cells","year":2024,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Trans-activating crRNA; CRISPR; RNA; Chemistry; Nanorobotics; Cleavage (geology); Ribonucleoprotein; Cas9; Guide RNA; Nucleic acid; Computational biology; Cell biology; Gene; Biology; Biochemistry; Nanotechnology","score_opus":0.006099311789054297,"score_gpt":0.28669742580803015,"score_spread":0.28059811401897583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401868077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960168,0.0010287078,0.0022103863,0.00037575775,0.00024679804,0.0000407056,0.000001983939,0.000006292952,0.00007253917],"genre_scores_gemma":[0.9960839,0.0002918134,0.0028367967,0.00031212592,0.00037077675,0.0000014736194,6.3065346e-7,0.000020629937,0.00008184938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992202,0.000031441552,0.00026647074,0.0001452214,0.00014321804,0.00019342975],"domain_scores_gemma":[0.9996072,0.00004731223,0.00010476295,0.00014153706,0.000041419375,0.00005775398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022076663,0.00011584201,0.00018069414,0.000014273312,0.000031523607,0.000040563085,0.00024619154,0.000056264027,0.000008015988],"category_scores_gemma":[0.000089198715,0.000081097176,0.00031861334,0.00023327419,0.0000862588,0.000005216637,0.00013407678,0.00031553995,0.0000010616602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000041616318,0.000020639183,0.00036745827,0.000018785175,0.000060429564,0.0000030519145,0.00020043613,0.0016011804,0.99255484,8.0062205e-7,0.003730823,0.0014373653],"study_design_scores_gemma":[0.00008515763,0.00005173777,0.00071072625,0.000121305355,0.0000174511,0.00004429724,0.00028787117,0.0009679049,0.9951379,0.0000051464135,0.002462961,0.00010758817],"about_ca_topic_score_codex":0.00001785303,"about_ca_topic_score_gemma":9.134759e-7,"teacher_disagreement_score":0.0025829843,"about_ca_system_score_codex":0.00005349156,"about_ca_system_score_gemma":0.0000688891,"threshold_uncertainty_score":0.3307047},"labels":[],"label_agreement":null},{"id":"W4401905192","doi":"10.1007/978-1-0716-4108-8_7","title":"CRISPR-Mediated Library Screening of Gene-Knockout Cell Lines for Investigating Antiviral Innate Immunity","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Innate immune system; Biology; Functional genomics; Computational biology; Genome editing; Gene; Forward genetics; Immunity; Intrinsic immunity; Immune system; Genetics; Genomics; Genome","score_opus":0.02105414676460726,"score_gpt":0.4040182548027716,"score_spread":0.38296410803816433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401905192","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.22822253,0.0074649476,0.7634659,0.00007192534,0.00024684364,0.00021268766,0.00005417403,0.00003466927,0.00022633793],"genre_scores_gemma":[0.27452734,0.00016152581,0.7245831,0.0001452346,0.000103909435,0.00004313625,0.0003111355,0.000052437037,0.000072171664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998323,0.00041837976,0.00043642087,0.00043271424,0.000049462236,0.00034000608],"domain_scores_gemma":[0.9993283,0.00018267747,0.00007108103,0.0003240521,0.000038023412,0.000055876197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007442005,0.0002248996,0.00030182407,0.00019739989,0.00003455043,0.000020984715,0.00027332536,0.00030972908,0.000005470709],"category_scores_gemma":[0.00048477226,0.0002225723,0.00016603316,0.0003030319,0.00012839983,0.0000059759795,0.00019762044,0.00021477975,8.189144e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022842938,0.000019573134,0.001348235,0.00016626844,0.000050566836,0.000005550478,0.00007689626,0.0005126042,0.9848942,0.00015363368,0.000058047128,0.0126915425],"study_design_scores_gemma":[0.00034136898,0.00021682057,0.0002774694,0.00005143957,0.000022784709,0.0000057471875,0.000052560365,0.006669507,0.985903,0.000748412,0.0054756,0.0002352643],"about_ca_topic_score_codex":0.00001958636,"about_ca_topic_score_gemma":0.0000030648748,"teacher_disagreement_score":0.04630483,"about_ca_system_score_codex":0.0000050662143,"about_ca_system_score_gemma":0.000076600154,"threshold_uncertainty_score":0.9076235},"labels":[],"label_agreement":null},{"id":"W4401905203","doi":"10.1007/978-1-0716-4108-8_6","title":"CRISPR-Mediated Viral Gene Knockout to Investigate Viral Evasion of Antiviral Innate Immunity","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Biology; Innate immune system; Gene; Acquired immune system; Genome editing; Immune system; Herpes simplex virus; Virology; Evasion (ethics); Computational biology; Virus; Genetics","score_opus":0.01541367251747511,"score_gpt":0.41249665348794856,"score_spread":0.39708298097047345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401905203","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49173537,0.002459484,0.5049272,0.0000929501,0.00036837434,0.00017825623,0.00002861791,0.00002518304,0.00018452408],"genre_scores_gemma":[0.69744664,0.00015284697,0.30174333,0.00028158276,0.00007899046,0.00003504839,0.00015180722,0.000045310484,0.000064469816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977062,0.0007220535,0.00047873115,0.0005648649,0.000090996604,0.0004371498],"domain_scores_gemma":[0.9992129,0.00006537488,0.000051083964,0.0005078312,0.000056844114,0.00010592772],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011195106,0.0002820497,0.0003670367,0.00030859848,0.000030813208,0.000017846512,0.00034361382,0.00035231924,0.000010877831],"category_scores_gemma":[0.00059210573,0.00027378454,0.00015924306,0.00039451744,0.00015286992,0.000004120602,0.00038453555,0.00029037346,0.000010972394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052443902,0.000030908242,0.0005738993,0.00005428825,0.00006330672,0.000022889979,0.000099851975,0.0004421516,0.98329693,0.0003314911,0.000051793544,0.014980055],"study_design_scores_gemma":[0.0003158348,0.0004626876,0.0008624852,0.000039590635,0.000022492019,0.000014249637,0.000020115374,0.0013351421,0.98860836,0.0011354468,0.006886011,0.0002976081],"about_ca_topic_score_codex":0.0000876961,"about_ca_topic_score_gemma":0.00001608077,"teacher_disagreement_score":0.20571125,"about_ca_system_score_codex":0.000025040325,"about_ca_system_score_gemma":0.00008041956,"threshold_uncertainty_score":0.99997145},"labels":[],"label_agreement":null},{"id":"W4401905253","doi":"10.1007/978-1-0716-4108-8_8","title":"CRISPR-Mediated Construction of Gene-Knockout Mice for Investigating Antiviral Innate Immunity","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Innate immune system; Biology; Gene knockout; Genome editing; Gene; Cas9; Immune system; Computational biology; Knockout mouse; Gene targeting; Immunity; Acquired immune system; Function (biology); Genetics","score_opus":0.01750498023665204,"score_gpt":0.41634626980106043,"score_spread":0.3988412895644084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401905253","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30955613,0.0025468704,0.68713313,0.00004592187,0.0003656343,0.00017568213,0.00003488467,0.00001768905,0.00012405963],"genre_scores_gemma":[0.28567004,0.00010112848,0.7138355,0.000075647404,0.00006565732,0.00004137986,0.00016510904,0.000028236549,0.000017333645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985821,0.00037190926,0.00036955604,0.0003668755,0.000042274987,0.00026726784],"domain_scores_gemma":[0.9994637,0.00012569375,0.000062417486,0.0002474106,0.00006150919,0.00003927622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088301185,0.0001739286,0.0002472134,0.00015726907,0.000029040295,0.00001070828,0.00016964535,0.00027371573,0.0000032301461],"category_scores_gemma":[0.0007533915,0.00017744378,0.00012305804,0.00023756851,0.00022845762,0.0000027213623,0.00008599928,0.0001691249,8.2889653e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018057743,0.000011888014,0.0006311716,0.000101550344,0.00006312465,0.0000023860978,0.0000804893,0.00015634962,0.9833299,0.0008566512,0.00001611408,0.014732306],"study_design_scores_gemma":[0.00029991977,0.00018310515,0.00018609836,0.00003398838,0.000023403589,0.000018916871,0.000088075714,0.0028208578,0.99090654,0.0019634098,0.0032918148,0.00018387508],"about_ca_topic_score_codex":0.000033762983,"about_ca_topic_score_gemma":0.000009044291,"teacher_disagreement_score":0.026702352,"about_ca_system_score_codex":0.000013552185,"about_ca_system_score_gemma":0.00007311696,"threshold_uncertainty_score":0.7235948},"labels":[],"label_agreement":null},{"id":"W4401983837","doi":"10.1101/2024.08.29.610263","title":"CRISPR/dCas-mediated counter-silencing – Reprogramming dCas proteins into antagonists of xenogeneic silencers","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Reprogramming; CRISPR; Gene silencing; Biology; Genetics; Argonaute; Computational biology; RNA interference; RNA; Gene","score_opus":0.007321891411488617,"score_gpt":0.25855986824310045,"score_spread":0.25123797683161186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401983837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97722197,0.013366682,0.0063579725,0.00008519266,0.001432629,0.0010499672,0.0002520327,0.00021999747,0.000013546869],"genre_scores_gemma":[0.9896043,0.0009765882,0.008052762,0.00006347736,0.00074251794,0.00031399712,0.000006202007,0.00023068664,0.000009499616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962741,0.00009125689,0.0008671346,0.0015814422,0.0004643669,0.0007217096],"domain_scores_gemma":[0.99709827,0.000026074633,0.0003820485,0.0017189882,0.00047833615,0.00029628002],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00068889395,0.00076749903,0.0006755865,0.00029345794,0.00012476546,0.00017328758,0.0007063654,0.000850885,0.000019790356],"category_scores_gemma":[0.00030687725,0.00084673875,0.00034319828,0.00046143399,0.00020330194,0.0000084499125,0.001213205,0.0007611919,0.00003374898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042459804,0.0000788343,0.0009102564,0.0018537762,0.00031975957,0.000062488005,0.000045345165,0.0006005041,0.99579597,0.000032698506,0.00023530351,0.000022616385],"study_design_scores_gemma":[0.00032469525,0.00019614186,0.0017615338,0.00085002393,0.00017582595,1.8089598e-7,0.000026101627,0.0007231649,0.9901922,0.000003847034,0.0048619523,0.0008843783],"about_ca_topic_score_codex":0.00023032517,"about_ca_topic_score_gemma":0.000019238109,"teacher_disagreement_score":0.012390094,"about_ca_system_score_codex":0.00017643253,"about_ca_system_score_gemma":0.00076947757,"threshold_uncertainty_score":0.99939835},"labels":[],"label_agreement":null},{"id":"W4401998861","doi":"10.1128/mbio.01798-24","title":"High-throughput transposon mutagenesis in the family Enterobacteriaceae reveals core essential genes and rapid turnover of essentiality","year":2024,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Directorate for Biological Sciences; Marsden Fund; Bayerisches Staatsministerium für Wissenschaft und Kunst; Australian Research Council; Wellcome Trust; King Abdullah University of Science and Technology; Royal Society Te Apārangi; Ministry of Business, Innovation and Employment; UK Research and Innovation","keywords":"Transposon mutagenesis; Transposable element; Mutagenesis; Enterobacteriaceae; Gene; Genetics; Sleeping Beauty transposon system; Biology; Computational biology; DNA Transposable Elements; Mutation; Genome; Escherichia coli","score_opus":0.010266885617355873,"score_gpt":0.2815235994174145,"score_spread":0.2712567138000586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401998861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98621273,0.009607801,0.0034262312,0.00010697673,0.0003870064,0.00014162267,0.00006470957,0.000009497001,0.000043431035],"genre_scores_gemma":[0.99821806,0.0011188026,0.00024512658,0.000055204346,0.00019930728,0.000010749521,0.000078825426,0.000015306412,0.000058622656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992467,0.000042412023,0.00020702841,0.0002625749,0.000091770366,0.0001495154],"domain_scores_gemma":[0.99969333,0.00001464759,0.000022735472,0.00022786578,0.000017030115,0.000024411114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019540312,0.00012663826,0.00014225724,0.000032950946,0.000022086027,0.000031292533,0.00012354643,0.00009809605,0.000019045785],"category_scores_gemma":[0.000006756916,0.00009893761,0.00007279439,0.000089572124,0.00006169412,0.0000037581199,0.000036918926,0.000057941088,0.0000013008608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032440006,0.000027759444,0.0017232695,0.00015966609,0.000043408523,0.0000082954075,0.00025896012,0.000049543454,0.9945941,0.00008591371,0.00042054566,0.0025960957],"study_design_scores_gemma":[0.00047755297,0.0001447524,0.10374069,0.000076378084,0.000072719915,0.000023036564,0.00016000024,0.000070553644,0.8844734,0.000096088894,0.010450114,0.00021473787],"about_ca_topic_score_codex":0.00010805225,"about_ca_topic_score_gemma":0.000065795466,"teacher_disagreement_score":0.110120736,"about_ca_system_score_codex":0.000004437374,"about_ca_system_score_gemma":0.000016806165,"threshold_uncertainty_score":0.40345585},"labels":[],"label_agreement":null},{"id":"W4402072935","doi":"10.5376/lgg.2024.15.0020","title":"CRISPR/Cas9 Genome Editing in Legumes: Opportunities for Functional Genomics and Breeding","year":2024,"lang":"en","type":"article","venue":"Legume Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Genomics; Functional genomics; Biology; Genome; Computational biology; Genetics; Gene","score_opus":0.02847308651354584,"score_gpt":0.2777563198513749,"score_spread":0.24928323333782904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402072935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93099344,0.029409135,0.03764219,0.0004874097,0.0006851851,0.0003135553,0.00014296798,0.000025473719,0.0003006509],"genre_scores_gemma":[0.98462576,0.007413237,0.0051293294,0.0002493629,0.0015682192,0.00004847885,0.00018843751,0.00008049343,0.0006966979],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99868506,0.000014170341,0.00032494252,0.0005101873,0.000084678155,0.0003809384],"domain_scores_gemma":[0.99955684,0.000035819856,0.000038532566,0.00018616392,0.000049309805,0.0001333404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002888801,0.00025395807,0.00020241168,0.00013888122,0.00011618576,0.00017618085,0.000103444,0.0001856087,0.000006354721],"category_scores_gemma":[0.000020969193,0.00028458604,0.000072309966,0.00006260447,0.00008887957,0.000008376273,0.00017162322,0.00013197547,0.0000012395769],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053626372,0.00002938054,0.0015071078,0.00047936014,0.00016429431,0.00002457994,0.00079739105,0.005376485,0.95338833,0.0012450482,0.0012514483,0.03568295],"study_design_scores_gemma":[0.0015328291,0.00066607195,0.007843222,0.000101182806,0.0001611792,0.0003274543,0.0034911076,0.044157866,0.062253363,0.0014376363,0.876741,0.0012870929],"about_ca_topic_score_codex":0.000008361437,"about_ca_topic_score_gemma":0.000043840762,"teacher_disagreement_score":0.891135,"about_ca_system_score_codex":0.000036914404,"about_ca_system_score_gemma":0.00009798217,"threshold_uncertainty_score":0.9999606},"labels":[],"label_agreement":null},{"id":"W4402126059","doi":"10.70099/bj/2024.09.01.33","title":"10.70099/BJ/2024.09.01.33","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Orange (colour); Subgenomic mRNA; Gene; Biology; Chemistry; Computational biology; Genetics; Food science","score_opus":0.0030496090254003975,"score_gpt":0.21658286416876646,"score_spread":0.21353325514336607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402126059","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02091047,0.0005185302,0.00007967703,0.0001422007,0.000012753381,0.00015178474,0.000026021857,0.000048257145,0.9781103],"genre_scores_gemma":[0.006735608,0.0000049808814,0.0002876516,0.00007079855,0.0002554034,0.000013944421,0.00004648176,0.000028168824,0.992557],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932504,0.000011297527,0.00011534602,0.00023879576,0.00008094131,0.00022859122],"domain_scores_gemma":[0.99954903,0.000004568858,0.000010085546,0.00030098791,0.00001960141,0.00011571898],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00005928855,0.0001267049,0.00009788268,0.00002726478,0.000034521978,0.000018806157,0.00014748558,0.00008434684,0.80781746],"category_scores_gemma":[0.000016374563,0.00013165695,0.000060904284,0.0000785994,0.000015446485,0.0000013895689,0.00004658641,0.000050670118,0.5493864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101016456,0.0000485385,0.0000020509615,0.000013530481,0.00004938093,0.000008546597,0.0000145648355,0.0024536168,0.11950956,8.320095e-7,0.3018291,0.5759693],"study_design_scores_gemma":[0.00017242358,0.00016273286,0.000071977076,0.0000057538605,0.000010798276,0.000014553674,8.8826323e-7,0.00011864148,0.028258095,0.0000014823892,0.9710075,0.00017510328],"about_ca_topic_score_codex":0.0000077768345,"about_ca_topic_score_gemma":3.4865764e-7,"teacher_disagreement_score":0.6691785,"about_ca_system_score_codex":0.0000071237323,"about_ca_system_score_gemma":0.000018327804,"threshold_uncertainty_score":0.5368815},"labels":[],"label_agreement":null},{"id":"W4402168894","doi":"10.3390/ijms25179493","title":"An Inducible Luminescent System to Explore Parkinson’s Disease-Associated Genes","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Health Canada; Montreal Neurological Institute and Hospital","funders":"","keywords":"Biology; Induced pluripotent stem cell; Gene; HEK 293 cells; Cell biology; Genetics; Molecular biology; Embryonic stem cell","score_opus":0.019818980792798355,"score_gpt":0.33627933176549707,"score_spread":0.3164603509726987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402168894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9682975,0.004070375,0.025481977,0.0004819454,0.0014973459,0.000049228587,0.000007815183,0.000012341034,0.000101500365],"genre_scores_gemma":[0.9982452,0.00010782941,0.0011230344,0.00012929311,0.0003474257,0.0000038988655,0.0000073912724,0.000010433769,0.000025509042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894804,0.00003228926,0.00021683899,0.00020662976,0.00046460715,0.00013158939],"domain_scores_gemma":[0.99948,0.000006154553,0.000052861848,0.000098341465,0.00020252817,0.00016008601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003555419,0.00009059359,0.00007966013,0.00017265667,0.00003478873,0.00016515602,0.0005168216,0.00003508091,0.000005718159],"category_scores_gemma":[0.000054289627,0.00007655641,0.00009562638,0.00014498703,0.000036207697,0.000013859287,0.000058641555,0.000053616965,0.000004366764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039392155,0.00006593868,0.0031782975,0.000017919343,0.00014216933,0.0003932521,0.00021128413,0.028047469,0.9586184,0.0002986506,0.00058633985,0.008400879],"study_design_scores_gemma":[0.00048293272,0.0010398742,0.013142409,0.0006824927,0.00007741048,0.000420181,0.001555012,0.011775326,0.9114457,0.00011153262,0.05876015,0.0005069805],"about_ca_topic_score_codex":0.0000050434905,"about_ca_topic_score_gemma":0.0000033876458,"teacher_disagreement_score":0.058173813,"about_ca_system_score_codex":0.000039608556,"about_ca_system_score_gemma":0.00015203282,"threshold_uncertainty_score":0.312188},"labels":[],"label_agreement":null},{"id":"W4402256848","doi":"10.1089/aid.2024.17445.rfs2023","title":"Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for <i>AIDS Research and Human Retroviruses</i>","year":2024,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Human immunodeficiency virus (HIV); Virology; Gerontology; Environmental ethics; Medicine; Family medicine; Philosophy","score_opus":0.07902020392702941,"score_gpt":0.4389486429120389,"score_spread":0.3599284389850095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402256848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98204917,0.014778503,0.0004929167,0.00039948957,0.00019207985,0.0009406027,0.00020856115,0.00004793278,0.0008907564],"genre_scores_gemma":[0.988827,0.0021368642,0.00052191044,0.00010098332,0.0012671102,0.0002881387,0.000121688514,0.00006800543,0.0066682966],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966423,0.00021978213,0.0003583183,0.00093283434,0.00079894776,0.0010477977],"domain_scores_gemma":[0.9982848,0.00036278306,0.00003132316,0.00061455794,0.00045390474,0.0002526083],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.004195199,0.00027712557,0.00026440635,0.00021435905,0.0014883142,0.000722115,0.00048524773,0.00028633454,0.000026574306],"category_scores_gemma":[0.00028368062,0.00020884794,0.00015522342,0.0004895883,0.0011951413,0.00002449836,0.0005612928,0.000856599,0.000011224858],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002666488,0.00018412183,0.034616146,0.0008240079,0.00043017915,0.00001616229,0.0010777452,0.000011497777,0.7440235,0.011680514,0.20249061,0.004378847],"study_design_scores_gemma":[0.001187318,0.01255619,0.013901129,0.00026253937,0.000049545997,0.000022590575,0.001959358,0.00003136913,0.14200824,0.0071656853,0.82021743,0.00063862285],"about_ca_topic_score_codex":0.0003476985,"about_ca_topic_score_gemma":0.00034155312,"teacher_disagreement_score":0.6177268,"about_ca_system_score_codex":0.00005319626,"about_ca_system_score_gemma":0.00016484383,"threshold_uncertainty_score":0.9998116},"labels":[],"label_agreement":null},{"id":"W4402285197","doi":"10.1016/j.ymthe.2024.08.021","title":"Hybrid non-viral and viral delivery strategy achieves potent gene editing in growing livers with reduced viral dosage","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Connaught Fund; Canada Research Chairs; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada; J.P. Bickell Foundation","keywords":"Virology; Gene delivery; Biology; Gene; Viral vector; Computational biology; Genetic enhancement; Genetics; Recombinant DNA","score_opus":0.004462531484139635,"score_gpt":0.24249050881578732,"score_spread":0.23802797733164768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402285197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812469,0.008344334,0.00979455,0.00008678873,0.00014571966,0.00020014313,0.000011330625,0.0000309486,0.0001392913],"genre_scores_gemma":[0.9976288,0.0007270203,0.0010264239,0.00017499976,0.00022211688,0.000021644924,0.00007086081,0.00005490044,0.00007323664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988142,0.000041227337,0.00018216188,0.00047696158,0.0001439586,0.00034147207],"domain_scores_gemma":[0.99965644,0.000006127292,0.000024305698,0.00021339707,0.000020592779,0.00007912885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013199137,0.00025150162,0.0001666234,0.00009414436,0.0000554675,0.00009762936,0.00012872931,0.00009194385,0.000005099866],"category_scores_gemma":[0.000004399521,0.00023082174,0.000083865154,0.00007165979,0.00005640648,0.000016073875,0.0000608974,0.00017931478,0.0000030280294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008518268,0.000023473647,0.00013733121,0.000023612405,0.00009756982,0.00028887074,0.0000953708,0.0045401566,0.9755061,0.000026286485,0.000026144153,0.01914988],"study_design_scores_gemma":[0.0008974079,0.00059721596,0.00145952,0.00006422514,0.000018544897,0.00008973566,0.0000945957,0.0031950371,0.99247336,0.000054634227,0.0007243329,0.00033137025],"about_ca_topic_score_codex":0.000054869346,"about_ca_topic_score_gemma":0.000005425548,"teacher_disagreement_score":0.01881851,"about_ca_system_score_codex":0.000020395397,"about_ca_system_score_gemma":0.0000516187,"threshold_uncertainty_score":0.94126374},"labels":[],"label_agreement":null},{"id":"W4402387545","doi":"","title":"Deciphering genome transplantation mechanisms as a step towards understanding basic principles of life","year":2024,"lang":"en","type":"article","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Computer science; Transplantation; Genome; Computational biology; Cognitive science; Biology; Psychology; Medicine; Genetics; Gene","score_opus":0.017354285128038032,"score_gpt":0.2534257877542382,"score_spread":0.23607150262620016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402387545","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2131331,0.0014334058,0.7743083,0.00037788678,0.00007234551,0.00010093976,0.000015883466,0.00004033559,0.010517795],"genre_scores_gemma":[0.9776168,0.00075844035,0.020357994,0.000021349786,0.000015766382,0.000011493896,0.000117722644,0.000024215336,0.0010762264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989496,0.00026496395,0.00021614056,0.00027237015,0.00014569963,0.00015126362],"domain_scores_gemma":[0.9992708,0.00008101383,0.000048797443,0.00036800368,0.00015101206,0.000080349215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009681528,0.00011410399,0.00010720985,0.00006437364,0.0000724479,0.000068306406,0.00021279317,0.00008015253,0.000041435662],"category_scores_gemma":[0.00016425292,0.00012154375,0.0000831804,0.0001533733,0.000043368454,0.000007862625,0.00008043381,0.0000752517,0.0000052026794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016782089,0.000050113256,0.00010249462,0.00024282649,0.00007634295,0.0000035265464,0.0021065746,0.0006684615,0.8917583,0.098735176,0.000019372605,0.006220006],"study_design_scores_gemma":[0.0003496128,0.0000023943217,0.0012038011,0.00043474627,0.000038990624,0.000020223644,0.00035078436,0.010088875,0.97880036,0.0009934906,0.0074838884,0.00023284947],"about_ca_topic_score_codex":0.00008637681,"about_ca_topic_score_gemma":0.00027048806,"teacher_disagreement_score":0.7644837,"about_ca_system_score_codex":0.000029293311,"about_ca_system_score_gemma":0.000116683004,"threshold_uncertainty_score":0.49564105},"labels":[],"label_agreement":null},{"id":"W4402405488","doi":"10.1371/journal.pone.0306158","title":"Heterogeneity in establishment of polyethylene glycol-mediated plasmid transformations for five forest pathogenic Phytophthora species","year":2024,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Genome Canada","keywords":"CRISPR; Transformation (genetics); Biology; Plasmid; Phytophthora sojae; Phytophthora; Genome editing; Phytophthora cactorum; Genetics; Gene; Microbiology; Botany","score_opus":0.02028578234815007,"score_gpt":0.26872860818937455,"score_spread":0.24844282584122448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402405488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99006724,0.0026014028,0.0061631245,0.00011998071,0.00006366782,0.0004036428,0.00040807005,0.000016881619,0.00015601414],"genre_scores_gemma":[0.9964981,0.0005737435,0.0021891806,0.000020130847,0.00009444366,0.00012421947,0.0003448893,0.000019074043,0.00013622978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992698,0.000012006065,0.00023064946,0.00019045702,0.00011305562,0.00018407237],"domain_scores_gemma":[0.9997023,0.00003101112,0.00002139817,0.00015494997,0.000045199635,0.00004516604],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009914875,0.00011050277,0.00015530433,0.00008001489,0.000020221456,0.000017156888,0.00009213822,0.000086438646,0.0000107280675],"category_scores_gemma":[0.000047608777,0.000113334434,0.00008606127,0.00012485072,0.000026137384,0.0000056698377,0.000024917375,0.000058350608,0.0000026501134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048976315,0.0002325834,0.0009815202,0.00037327016,0.00012029529,0.0000016062677,0.00014469448,0.0007424144,0.9969897,0.000042169446,0.000090179645,0.00023256807],"study_design_scores_gemma":[0.00040851365,0.000263546,0.0047704377,0.00011622669,0.00005329611,0.0000016478159,0.00007659028,0.0033614654,0.9897626,0.000042955933,0.0010059333,0.00013676309],"about_ca_topic_score_codex":0.0000062858503,"about_ca_topic_score_gemma":0.00019108885,"teacher_disagreement_score":0.0072270986,"about_ca_system_score_codex":0.0000171193,"about_ca_system_score_gemma":0.000043122607,"threshold_uncertainty_score":0.4621644},"labels":[],"label_agreement":null},{"id":"W4402423858","doi":"10.1101/2024.09.09.612071","title":"Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Computational biology; Cancer research; Computer science; Biology; Chemistry; Genetics; Gene","score_opus":0.007976149504463261,"score_gpt":0.23801469363125724,"score_spread":0.23003854412679398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402423858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97625446,0.016776374,0.004623091,0.000102126694,0.0011484782,0.00058233767,0.00038482397,0.00011562304,0.000012666486],"genre_scores_gemma":[0.9918777,0.0012870145,0.0058447574,0.00010351085,0.0005105212,0.00016033348,0.0000014924495,0.00017226573,0.00004240399],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971397,0.00006277925,0.0005993634,0.0013343192,0.00026254606,0.0006013188],"domain_scores_gemma":[0.998355,0.000033253928,0.00012643912,0.0010939986,0.0001734353,0.00021788813],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038746424,0.000649365,0.0005202604,0.00026538104,0.000080442136,0.00029935487,0.00042191436,0.00064122916,0.000022994529],"category_scores_gemma":[0.00010141106,0.00073630654,0.00016675958,0.00023687466,0.00017308614,0.0000073597002,0.0011822301,0.0006893823,0.000023016297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025455523,0.00006135551,0.0017859873,0.00068973587,0.00012467003,0.00003429936,0.000022025963,0.0010827774,0.99562746,0.00005044785,0.00048614532,0.0000096505],"study_design_scores_gemma":[0.0004777534,0.00007664011,0.03516836,0.0003634422,0.00009959856,9.498543e-8,0.000011314251,0.00062926725,0.96011204,0.000009634982,0.002207157,0.0008446874],"about_ca_topic_score_codex":0.00030235932,"about_ca_topic_score_gemma":0.00006140454,"teacher_disagreement_score":0.0355154,"about_ca_system_score_codex":0.000077566554,"about_ca_system_score_gemma":0.0002740445,"threshold_uncertainty_score":0.9995088},"labels":[],"label_agreement":null},{"id":"W4402449104","doi":"10.1038/s41467-024-51457-9","title":"RNA-mediated double-strand break repair by end-joining mechanisms","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Science Foundation; National Institutes of Health; U.S. Department of Health and Human Services; Howard Hughes Medical Institute; Southeast Center for Mathematics and Biology","keywords":"Non-homologous end joining; Homologous recombination; Biology; RNA; DNA; DNA repair; Genetics; DNA repair protein XRCC4; Cell biology; Gene; Computational biology; Nucleotide excision repair","score_opus":0.00919595404971189,"score_gpt":0.3151911108364129,"score_spread":0.305995156786701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402449104","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09451276,0.68820816,0.119516276,0.016759118,0.0033082983,0.0016247513,0.0011984095,0.0020443508,0.07282786],"genre_scores_gemma":[0.9887343,0.002079263,0.006912163,0.00027474263,0.00007773516,0.000038210215,0.0011544711,0.000030780375,0.0006983105],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932057,0.000028871116,0.00015689805,0.00023158398,0.00009653891,0.00016552389],"domain_scores_gemma":[0.99879444,0.0000460194,0.000019616185,0.0010231098,0.00004894429,0.00006789801],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016039476,0.00012675773,0.00008917248,0.00004658347,0.000113869304,0.000043432352,0.00044866788,0.00031157513,0.000026400538],"category_scores_gemma":[0.0000383854,0.00012592097,0.000101301026,0.00016454079,0.000044233762,0.000004049267,0.00019529794,0.00048100136,0.000018086539],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014358776,0.000037717924,0.00003401572,0.000025297953,0.00011904263,0.0000019240413,0.00008712589,0.000047844114,0.9378907,0.004583893,0.055601865,0.0015562124],"study_design_scores_gemma":[0.0003330941,0.000053094307,0.00010696442,0.000036177327,0.000041104955,0.000022004428,0.00006176292,0.001880468,0.19190603,0.000100520716,0.8052422,0.00021659188],"about_ca_topic_score_codex":0.000011958012,"about_ca_topic_score_gemma":0.00009864712,"teacher_disagreement_score":0.89422154,"about_ca_system_score_codex":0.000013109681,"about_ca_system_score_gemma":0.00004925312,"threshold_uncertainty_score":0.5134908},"labels":[],"label_agreement":null},{"id":"W4402506209","doi":"10.31219/osf.io/2xq5e","title":"African biodiversity genomics in the era of the Kunming-Montreal Global Biodiversity Framework: Ethical, Legal, and Social Perspectives","year":2024,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Convention on Biological Diversity; Biodiversity; Food security; Data sharing; Interoperability; Capacity building; Context (archaeology); Environmental resource management; Sustainability; Political science; Business; Environmental planning; Public relations; Geography; Medicine; Ecology; Biology","score_opus":0.009331219108691434,"score_gpt":0.2765871079851196,"score_spread":0.26725588887642815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402506209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876753,0.002421881,0.00061211176,0.007233194,0.00022827477,0.0002563572,0.0005993472,0.000011289231,0.0009622398],"genre_scores_gemma":[0.9985893,0.0003996799,0.0004965717,0.0003633115,0.000103711645,0.0000033876154,0.000026709042,0.0000032831938,0.000014093451],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.9989849,0.000089213165,0.0001458989,0.0004314847,0.00015730307,0.00019125537],"domain_scores_gemma":[0.99951285,0.000019783914,0.00005920345,0.0003279196,0.000051336487,0.000028930599],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023663735,0.0002028667,0.0001954036,0.00002173438,0.00012963125,0.00006786232,0.00047768245,0.00067228585,0.000007642215],"category_scores_gemma":[0.000043969045,0.00014084573,0.00019523285,0.000102399135,0.00032930067,9.575821e-7,0.0019069865,0.001171769,0.000002353874],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028527987,0.003097326,0.184148,0.0064578005,0.007267308,0.00032327746,0.35913,0.011441934,0.10178682,0.05256782,0.23408799,0.036838945],"study_design_scores_gemma":[0.0029879743,0.00080117286,0.6759579,0.00049361,0.0020985715,0.000126444,0.18126091,0.0010599114,0.043191697,0.022627115,0.065292574,0.004102128],"about_ca_topic_score_codex":0.0016085134,"about_ca_topic_score_gemma":0.0009291263,"teacher_disagreement_score":0.4918099,"about_ca_system_score_codex":0.000056640776,"about_ca_system_score_gemma":0.00014331375,"threshold_uncertainty_score":0.57435226},"labels":[],"label_agreement":null},{"id":"W4402551741","doi":"10.1158/1538-7445.pancreatic24-a010","title":"Abstract A010: A patient first approach using CRISPR-directed gene editing as an augmentative therapy for the treatment of pancreatic ductile adenocarcinoma","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Genetic enhancement; Genome editing; Medicine; Adenocarcinoma; Pancreatic cancer; Gene; Internal medicine; Cancer; Biology; Genetics","score_opus":0.07510771090053593,"score_gpt":0.4341230013169925,"score_spread":0.3590152904164566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402551741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95542985,0.040779255,0.0024939494,0.00006998184,0.00019906688,0.00085701374,0.00008349606,0.000016599959,0.000070805356],"genre_scores_gemma":[0.99370277,0.0038215364,0.0009238841,0.000009005765,0.00067736325,0.00066947663,0.000066662345,0.00003860786,0.00009072071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890894,0.000051467785,0.00016620061,0.00035645647,0.00020639993,0.00031053156],"domain_scores_gemma":[0.99937856,0.00010070763,0.00002703275,0.00027513955,0.00015094398,0.00006761349],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002299295,0.00013470075,0.00013151829,0.00006513856,0.00017728294,0.000050671686,0.00013243902,0.00006535069,0.000042434865],"category_scores_gemma":[0.00002961178,0.000094431125,0.000090605936,0.00016688679,0.00009379769,0.0000053486506,0.000026810541,0.00008127453,9.079165e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029408003,0.00022046355,0.00038431157,0.00018604346,0.00041675346,0.0000053224376,0.0038547763,0.0051618465,0.9544806,0.000013904275,0.0005081328,0.03447375],"study_design_scores_gemma":[0.0004912068,0.0012542993,0.0015146199,0.000050195245,0.000036102723,0.000008844757,0.0019077081,0.008857433,0.97966206,0.000024269033,0.0060689845,0.00012426781],"about_ca_topic_score_codex":0.00086676306,"about_ca_topic_score_gemma":0.000048943835,"teacher_disagreement_score":0.03827291,"about_ca_system_score_codex":0.00010104629,"about_ca_system_score_gemma":0.00016710968,"threshold_uncertainty_score":0.38507897},"labels":[],"label_agreement":null},{"id":"W4402564281","doi":"10.1016/j.xpro.2024.103307","title":"A protocol for the detection of precision genome editing in human cells using One-pot DTECT","year":2024,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"University of Calgary; Cumming School of Medicine, University of Calgary; Calgary Foundation; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Arnie Charbonneau Cancer Institute, University of Calgary","keywords":"Protocol (science); Human genome; Computational biology; Computer science; Genome; Biology; Genetics; Gene; Medicine","score_opus":0.040454709153634805,"score_gpt":0.3990694394366358,"score_spread":0.358614730283001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402564281","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.024065752,0.000032360695,0.15544386,0.000010180993,0.000052069314,0.82029444,0.00001693003,0.000018786233,0.000065609944],"genre_scores_gemma":[0.2555525,3.1284387e-7,0.0015193867,0.0000040941545,0.00028962604,0.74257,0.0000031199156,0.000022686287,0.00003827869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920917,0.000027533299,0.0002536312,0.00023303826,0.000101378675,0.00017528195],"domain_scores_gemma":[0.99964845,0.000023635652,0.000048423004,0.00021420336,0.0000438618,0.000021412969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039599137,0.00010763188,0.000104469145,0.000057567362,0.00006254118,0.000034361896,0.00012485047,0.000085267195,0.000009297859],"category_scores_gemma":[0.00003248401,0.000085621155,0.000077667144,0.000110964334,0.000024441222,0.000003925462,0.000059956834,0.00008822515,5.60859e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069856666,0.000024541987,0.0000133249905,0.00047735398,0.000015662883,4.5957765e-7,0.00006599129,0.002196618,0.99204785,0.0000069895664,0.000011674609,0.005069651],"study_design_scores_gemma":[0.0005218232,0.0004242766,0.00016843884,0.00024511476,0.0000067742194,0.0000019943234,0.000031446536,0.00491483,0.96031064,0.00009794863,0.03317912,0.00009762301],"about_ca_topic_score_codex":0.00001896415,"about_ca_topic_score_gemma":0.00003785971,"teacher_disagreement_score":0.23148675,"about_ca_system_score_codex":0.000023904393,"about_ca_system_score_gemma":0.000041598825,"threshold_uncertainty_score":0.34915292},"labels":[],"label_agreement":null},{"id":"W4402566027","doi":"10.1080/10408347.2024.2400267","title":"CRISPR-Driven Biosensors: A New Frontier in Rapid and Accurate Disease Detection","year":2024,"lang":"en","type":"review","venue":"Critical Reviews in Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"CRISPR; Frontier; Computational biology; Computer science; Nanotechnology; Biology; Materials science; Genetics; Geography; Gene","score_opus":0.039050927271326134,"score_gpt":0.41242564201470494,"score_spread":0.3733747147433788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402566027","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000028817367,0.9972856,0.0014962177,0.000105102044,0.00013924888,0.00039765026,0.00003096434,0.000015818143,0.0005005514],"genre_scores_gemma":[0.0009750587,0.9971724,0.00025515576,0.00005412149,0.0005342308,0.000092017246,0.00008971061,0.000065832006,0.00076144416],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973014,0.00010595162,0.0009747475,0.00097578135,0.00014952516,0.00049260363],"domain_scores_gemma":[0.9987622,0.00008091757,0.00005445615,0.0005427047,0.000026082398,0.0005336741],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003096568,0.00056996755,0.0013943838,0.000104122715,0.000021383195,0.00008237459,0.0002490246,0.0005512458,0.00007735099],"category_scores_gemma":[0.0024344893,0.0004792868,0.0005136056,0.000361688,0.00015827757,0.000005538646,0.00023817261,0.0007392368,0.000049970306],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003184432,0.000121644814,0.000012127757,0.076556794,0.000100168036,0.00023131854,0.000012114297,0.000007594078,0.00058808754,0.000065164226,0.004694886,0.9175783],"study_design_scores_gemma":[0.00015295942,0.0000241823,0.0000049566393,0.011170733,0.00072278565,0.000036845107,0.0000064021438,0.0008817207,0.00017432756,0.0000951207,0.98618746,0.0005424965],"about_ca_topic_score_codex":0.000004748399,"about_ca_topic_score_gemma":0.000007594078,"teacher_disagreement_score":0.9814926,"about_ca_system_score_codex":0.00008056305,"about_ca_system_score_gemma":0.00018303219,"threshold_uncertainty_score":0.9997659},"labels":[],"label_agreement":null},{"id":"W4402586491","doi":"10.1038/s41467-024-52490-4","title":"Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; Damon Runyon Cancer Research Foundation; National Human Genome Research Institute; University of California, San Francisco; U.S. Department of Health and Human Services; National Science Foundation","keywords":"CRISPR; Biology; Enhancer; Computational biology; Gene; Regulation of gene expression; Promoter; Genetics; Chromatin; Gene expression","score_opus":0.027139420704156057,"score_gpt":0.3341607808195428,"score_spread":0.3070213601153868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402586491","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.22232987,0.58433235,0.16561164,0.0030439561,0.0028826348,0.0019286093,0.00033298854,0.0003802784,0.019157695],"genre_scores_gemma":[0.9356665,0.001006487,0.06117043,0.00013244445,0.00017301727,0.00003258669,0.0005655943,0.000039049137,0.001213912],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99931747,0.000025030218,0.00017175805,0.00023458924,0.00007880107,0.00017236384],"domain_scores_gemma":[0.99869066,0.000054103915,0.000028825209,0.0010773528,0.000098095166,0.00005096858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014099001,0.00012205737,0.00007912318,0.000054948967,0.00012811605,0.00004940379,0.0004811511,0.00022779997,0.000010728076],"category_scores_gemma":[0.000030007912,0.00012907595,0.00008775131,0.00013165716,0.000037925318,0.0000039998163,0.00020058139,0.00029433597,0.000010627571],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014752932,0.00008080837,0.00024611593,0.0000422,0.000028286575,3.8121135e-7,0.000052403244,0.0001306216,0.9478657,0.00030265743,0.047898255,0.0033378087],"study_design_scores_gemma":[0.00021353885,0.00007115219,0.00038668537,0.000019387511,0.00001857686,0.0000019412857,0.000054732565,0.0014990657,0.21051933,0.00001752642,0.7870566,0.00014145255],"about_ca_topic_score_codex":0.0000013667027,"about_ca_topic_score_gemma":0.000020961197,"teacher_disagreement_score":0.73915833,"about_ca_system_score_codex":0.00001546539,"about_ca_system_score_gemma":0.000030041596,"threshold_uncertainty_score":0.52635646},"labels":[],"label_agreement":null},{"id":"W4402645288","doi":"10.1002/advs.202405628","title":"Efficient Rescue of Retinal Degeneration in <i>Pde6a</i> Mice by Engineered Base Editing and Prime Editing","year":2024,"lang":"en","type":"article","venue":"Advanced Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; School of Medicine, Stanford University; National Institutes of Health; Children's Health Research Institute; International Retinal Research Foundation; U.S. Department of Veterans Affairs","keywords":"Prime (order theory); Retinal degeneration; Base (topology); Degeneration (medical); Retinal; Computer science; Medicine; Ophthalmology; Mathematics; Combinatorics","score_opus":0.003244076701889193,"score_gpt":0.26360569256171124,"score_spread":0.26036161585982204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402645288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.947075,0.0028488287,0.049529657,0.000055310382,0.0002717858,0.00007871478,0.000008169165,0.000011666041,0.000120840356],"genre_scores_gemma":[0.99316067,0.00003687754,0.0065989946,0.000016924236,0.00012790311,0.0000056948716,0.000010509459,0.000008056654,0.000034368608],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919724,0.000009275616,0.00015582664,0.00031384671,0.00013851243,0.00018526532],"domain_scores_gemma":[0.9997672,0.000015226268,0.000019277026,0.000105986015,0.000043267646,0.000049057897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036878153,0.000080165446,0.00006863489,0.00006352211,0.000045374454,0.000023345598,0.00009403901,0.000033124186,9.1341997e-7],"category_scores_gemma":[0.00019836712,0.000081109974,0.000016115946,0.00026666842,0.000096645,0.0000069324615,0.000059134894,0.00006788029,3.722314e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003418721,0.000006142453,0.00006204089,0.000026651289,8.5205477e-7,0.0000013659718,0.00007272708,0.04223179,0.9548184,0.00006859537,0.000025929165,0.0026820456],"study_design_scores_gemma":[0.000113432536,0.000049294027,0.00016668063,0.00006978879,0.000002438259,0.00000780996,0.00010080607,0.06539524,0.9337196,0.0000066734215,0.00028983303,0.00007843903],"about_ca_topic_score_codex":0.000005816617,"about_ca_topic_score_gemma":0.000008950138,"teacher_disagreement_score":0.046085645,"about_ca_system_score_codex":0.000014969553,"about_ca_system_score_gemma":0.000044691278,"threshold_uncertainty_score":0.33075687},"labels":[],"label_agreement":null},{"id":"W4402684959","doi":"10.1002/em.22633","title":"Genotoxicity evaluation of gene therapies: A report from the International Workshop on Genotoxicity Testing ( <scp>IWGT</scp> ) 2022","year":2024,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Genotoxicity; Computational biology; Bioinformatics; Biology; Genetics; Medicine","score_opus":0.029540281357313763,"score_gpt":0.31856571658424004,"score_spread":0.28902543522692625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402684959","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13420682,0.8632347,0.0011333113,0.000013720152,0.00028034396,0.0006436051,0.00030928807,0.000012099496,0.00016614037],"genre_scores_gemma":[0.039753333,0.9569995,0.00069859845,0.000114015056,0.0004004527,0.00023157898,0.0014665725,0.00010365545,0.00023229163],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.997735,0.00016650754,0.0005014258,0.00076953205,0.0006049623,0.00022253185],"domain_scores_gemma":[0.9989441,0.000105427105,0.00024495783,0.00060830894,0.00002035602,0.00007686207],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059283915,0.00044547458,0.00047403265,0.000065375934,0.00008250158,0.000047058256,0.00036658088,0.00028653644,0.000031501662],"category_scores_gemma":[0.00020523103,0.0003366133,0.00035137407,0.00009684788,0.00010301061,0.0000033562546,0.00032897672,0.00021864762,0.000016289083],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004732642,0.00009842266,0.00005871143,0.000292408,0.0012000758,0.00007492289,0.00014635379,0.00033821972,0.5138845,0.0000019243485,0.0003919634,0.48350775],"study_design_scores_gemma":[0.0005263509,0.00016916958,0.0008284483,0.0013411433,0.004145776,0.00029864276,0.00036727844,0.00054075685,0.19297773,0.0000656845,0.7981773,0.00056174636],"about_ca_topic_score_codex":0.000020473472,"about_ca_topic_score_gemma":0.0000046990126,"teacher_disagreement_score":0.79778534,"about_ca_system_score_codex":0.00008335454,"about_ca_system_score_gemma":0.000084101994,"threshold_uncertainty_score":0.99990857},"labels":[],"label_agreement":null},{"id":"W4402693981","doi":"10.1101/2024.09.16.613289","title":"Proof of concept study deploying CRISPR inhibition and activation opens new avenues for systematic biological exploration in zebrafish","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Zebrafish; CRISPR; Key (lock); Computational biology; Biology; Computer science; Nanotechnology; Genetics; Ecology; Materials science; Gene","score_opus":0.02500979893719426,"score_gpt":0.2839450075390673,"score_spread":0.2589352086018731,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402693981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96082866,0.001513991,0.03457753,0.000054073444,0.00021672649,0.0027201958,0.000050246075,0.000037885806,7.037135e-7],"genre_scores_gemma":[0.99787694,0.000039715585,0.001215487,0.000019044886,0.00023495483,0.00055484904,0.0000026624389,0.000054437012,0.0000019348622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998514,0.0000897912,0.00049322506,0.0005866547,0.00012193311,0.00019441261],"domain_scores_gemma":[0.99918085,0.000031478918,0.00020097168,0.00036453936,0.00015190018,0.00007026321],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004034923,0.0002707838,0.00041371933,0.000143524,0.00003517148,0.0000753502,0.00011646487,0.0003107197,0.0000011165736],"category_scores_gemma":[0.0003221042,0.00026939847,0.00006997983,0.00014600731,0.000033757264,0.000011018988,0.00028101762,0.00020033952,4.1844052e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003944674,0.00010893239,0.0008312415,0.004993979,0.00009096562,0.0000031054183,0.00011338033,0.0009052893,0.9927813,0.00005035292,0.00007855196,0.0000034694824],"study_design_scores_gemma":[0.0005772324,0.0003060383,0.0040059634,0.0029182646,0.000074497024,2.0642455e-8,0.00007675382,0.00060971983,0.99108005,0.000017145576,0.000025778823,0.00030851853],"about_ca_topic_score_codex":0.000021912014,"about_ca_topic_score_gemma":0.000008367949,"teacher_disagreement_score":0.037048265,"about_ca_system_score_codex":0.000043521813,"about_ca_system_score_gemma":0.00014271177,"threshold_uncertainty_score":0.9999758},"labels":[],"label_agreement":null},{"id":"W4402755342","doi":"10.1093/nar/gkae819","title":"Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada); Université Laval; Feldan (Canada)","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Environmental Health Sciences; Québec Consortium for Drug Discovery; Roy J. Carver Charitable Trust; National Institutes of Health; National Human Genome Research Institute; Cystic Fibrosis Foundation","keywords":"Biology; Peptide; Ribonucleoprotein; Cell biology; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; Airway; Molecular biology; RNA; Biochemistry; Genetics; Gene; Medicine","score_opus":0.013921295872888128,"score_gpt":0.32152322719089793,"score_spread":0.3076019313180098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402755342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99085,0.00050408003,0.0050346586,0.0007172136,0.0014947844,0.0006763399,0.000064841166,0.000045076387,0.0006130509],"genre_scores_gemma":[0.99543357,0.00011824838,0.00040641124,0.00006607975,0.0017715642,0.0000920771,0.000075024414,0.0000544893,0.0019825245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980407,0.00018783654,0.00024537355,0.00052031555,0.0004607742,0.0005449966],"domain_scores_gemma":[0.9991766,0.000085488085,0.000015614603,0.00043202803,0.00013560455,0.00015465282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008823307,0.00018102137,0.00013410064,0.0002296806,0.00013746631,0.00012786823,0.00039017352,0.0001734439,0.00025471477],"category_scores_gemma":[0.00018012813,0.00014617371,0.00009360752,0.00054637005,0.000106259184,0.000007684347,0.00023453293,0.0004440809,0.0005830864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000104547325,0.000043195516,0.00009142321,0.000055691387,0.000029716002,0.000029608549,0.00043828963,0.0017006297,0.9496367,0.00001853812,0.03724012,0.010611568],"study_design_scores_gemma":[0.00046747137,0.00046767757,0.0013293851,0.00008417151,0.000011969999,0.000009305429,0.0005545693,0.009650843,0.8115498,0.000045021254,0.17555808,0.00027170806],"about_ca_topic_score_codex":0.00029446953,"about_ca_topic_score_gemma":0.00028303964,"teacher_disagreement_score":0.13831794,"about_ca_system_score_codex":0.00007707614,"about_ca_system_score_gemma":0.00010615423,"threshold_uncertainty_score":0.749459},"labels":[],"label_agreement":null},{"id":"W4402828852","doi":"10.1016/j.tim.2024.09.005","title":"The double play of a phage HTH regulator","year":2024,"lang":"en","type":"article","venue":"Trends in Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences; Fonds de recherche du Québec – Nature et technologies; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Regulator; Genetics; Computational biology; Virology; Gene","score_opus":0.0073823069357353615,"score_gpt":0.308271651693814,"score_spread":0.3008893447580786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402828852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98155314,0.014859395,0.0004899115,0.00021836223,0.00055424194,0.000059267328,0.00003098687,0.00001655477,0.0022181468],"genre_scores_gemma":[0.99640065,0.00018087355,0.00016987353,0.000018994022,0.00008969547,0.000008923676,0.00007260482,0.000012322964,0.003046073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994266,0.000019677362,0.0001613034,0.00019402031,0.000015971202,0.00018244192],"domain_scores_gemma":[0.99972355,0.000016727043,0.000016602673,0.00021588444,0.00001020341,0.000016999209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013784121,0.000088179084,0.000096081174,0.00006601703,0.000021642532,0.000008550465,0.00014555008,0.00010580585,0.000035432186],"category_scores_gemma":[0.000005668994,0.00006307749,0.0000623556,0.00012959474,0.00008818528,8.562805e-7,0.0000643519,0.00007525984,0.0000063017874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038284325,0.000010027643,0.00013440844,0.000010757117,0.000031027834,0.0000032308285,0.00005882574,0.00012751819,0.98470604,0.000377444,0.004742911,0.009759499],"study_design_scores_gemma":[0.00039873397,0.00012063247,0.0009884896,0.000015362031,0.00000898704,0.000057456717,0.000025949901,0.00006695339,0.7270757,0.00003320327,0.27110335,0.00010518053],"about_ca_topic_score_codex":0.00000988008,"about_ca_topic_score_gemma":0.0001021878,"teacher_disagreement_score":0.26636043,"about_ca_system_score_codex":0.0000071383615,"about_ca_system_score_gemma":0.000018506516,"threshold_uncertainty_score":0.25722253},"labels":[],"label_agreement":null},{"id":"W4402838870","doi":"10.1139/bcb-2024-0176","title":"Canada's contributions to RNA research: past, present, and future perspectives","year":2024,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"University of Toronto; York University; Université de Sherbrooke; Institut National de la Recherche Scientifique; Simon Fraser University; University of Manitoba; McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Viewpoints; RNA; Transformative learning; Humanity; Biology; Environmental ethics; Political science; Sociology; Genetics; Law","score_opus":0.01785299924838241,"score_gpt":0.3778754569816775,"score_spread":0.3600224577332951,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402838870","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00032919593,0.9959483,0.000027613843,0.00070575805,0.00020515798,0.0002969693,0.0009792028,0.000011022643,0.0014967631],"genre_scores_gemma":[0.0025784173,0.98973906,0.00004682183,0.000027457347,0.0045697824,0.00009164083,0.0004901132,0.000031894804,0.002424833],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99839634,0.00008407325,0.00023208663,0.00078258954,0.00008126189,0.0004236447],"domain_scores_gemma":[0.9991998,0.000036909325,0.00004013629,0.00035228228,0.00011076607,0.00026010524],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019293788,0.00034002372,0.0004800239,0.000060982813,0.00011797024,0.000038681046,0.00019896506,0.00057453965,0.0000115550665],"category_scores_gemma":[0.00003324018,0.0002807342,0.000103371254,0.0001564865,0.0001495351,7.898117e-7,0.0003880873,0.000397329,0.0000038612843],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036920355,0.000078349774,0.0000041803423,0.014444515,0.0005928958,0.000049235452,0.00011474887,0.00000114398,0.11081062,0.0003255217,0.29213926,0.5814026],"study_design_scores_gemma":[0.00008094977,0.000086380525,8.847743e-7,0.00024680624,0.00013906701,0.000046645102,0.00021928725,8.020394e-7,0.013708091,0.000011069013,0.98515874,0.00030128003],"about_ca_topic_score_codex":0.0020871144,"about_ca_topic_score_gemma":0.0007130073,"teacher_disagreement_score":0.69301945,"about_ca_system_score_codex":0.000059427784,"about_ca_system_score_gemma":0.0006552733,"threshold_uncertainty_score":0.9999645},"labels":[],"label_agreement":null},{"id":"W4402936306","doi":"10.1101/2024.09.27.615316","title":"Expanding the CRISPR toolbox by engineering Cas12a orthologs of metagenomic discovery","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; Foundation for Innovative Research Groups of the National Natural Science Foundation of China; National Natural Science Foundation of China","keywords":"Toolbox; CRISPR; Metagenomics; Computational biology; Biology; Computer science; Data science; Genetics; Gene; Programming language","score_opus":0.00652634112356114,"score_gpt":0.24100362974267642,"score_spread":0.23447728861911526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402936306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95876765,0.020166846,0.018492779,0.00010055711,0.0014970826,0.00043986234,0.00042519404,0.00009792233,0.000012109911],"genre_scores_gemma":[0.997089,0.0007550429,0.0012458573,0.00005806953,0.00051718875,0.00012754991,0.0000023042005,0.0001650179,0.00003995332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99784935,0.000051765954,0.0005306185,0.00085214886,0.00023109136,0.00048501368],"domain_scores_gemma":[0.9982947,0.0000346199,0.00018381525,0.0012535756,0.000113480965,0.00011980246],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046412458,0.00054577616,0.00047031912,0.00013657665,0.000072877716,0.00017839705,0.00061669113,0.00046754413,0.000008814933],"category_scores_gemma":[0.00014719565,0.0004796356,0.0003051687,0.00021945934,0.00009203096,0.000008040048,0.000882876,0.0006348604,0.00001149382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013739388,0.000027437662,0.00033054323,0.00043852342,0.00032404237,0.000014413423,0.00001141953,0.002423345,0.99522275,0.000095804775,0.0010960317,0.000001953983],"study_design_scores_gemma":[0.0001781582,0.00005248901,0.0025547417,0.00017957822,0.0002147449,1.0785288e-7,0.000007816445,0.00030477621,0.98901576,0.0000010963023,0.0069268597,0.00056388706],"about_ca_topic_score_codex":0.000033936187,"about_ca_topic_score_gemma":0.0000019302756,"teacher_disagreement_score":0.03832137,"about_ca_system_score_codex":0.00006505976,"about_ca_system_score_gemma":0.00021478758,"threshold_uncertainty_score":0.9997655},"labels":[],"label_agreement":null},{"id":"W4402944539","doi":"10.1101/2024.09.27.24314122","title":"Consensus guidelines for eligibility assessment of pathogenic variants to antisense oligonucleotide treatments","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"Medical Research Council","keywords":"Oligonucleotide; Computational biology; Biology; Genetics; Gene","score_opus":0.04373895124442535,"score_gpt":0.43119193882228507,"score_spread":0.38745298757785973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402944539","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98389214,0.0018612545,0.010762733,0.0003810749,0.0010656475,0.0009106685,0.000873216,0.000028538687,0.00022474144],"genre_scores_gemma":[0.96483785,0.00028038694,0.033767343,0.00009684223,0.00030542273,0.000136495,0.0001911668,0.000060319748,0.00032419263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815404,0.000041461848,0.00059317873,0.0007770265,0.00015798461,0.00027628796],"domain_scores_gemma":[0.9985289,0.000025265672,0.000105984065,0.0008502744,0.0003600944,0.00012946488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043150014,0.00032621197,0.00041336502,0.00008350763,0.00002760941,0.000023122864,0.00023129136,0.00024882948,0.000007642978],"category_scores_gemma":[0.0002801297,0.00030609558,0.00031382445,0.000071574905,0.000041414813,3.516485e-7,0.0006676293,0.00012782466,0.000004871913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004486971,0.00008216962,0.0042274124,0.0005358026,0.00042060667,0.000014133882,0.000029563822,0.007009823,0.98198915,0.00003677515,0.0027398637,0.002869841],"study_design_scores_gemma":[0.0013104721,0.0010125033,0.08091964,0.00054823066,0.00082664646,0.000042660104,0.00006783384,0.0091515295,0.8943354,0.0017051721,0.008946364,0.0011335807],"about_ca_topic_score_codex":0.00003499642,"about_ca_topic_score_gemma":0.000028302387,"teacher_disagreement_score":0.08765377,"about_ca_system_score_codex":0.000029456978,"about_ca_system_score_gemma":0.00023027913,"threshold_uncertainty_score":0.99993914},"labels":[],"label_agreement":null},{"id":"W4402944912","doi":"10.1016/j.xpro.2024.103352","title":"Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs","year":2024,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Scottish Rite Charitable Foundation of Canada; Simons Foundation Autism Research Initiative; Simons Foundation","keywords":"CRISPR; Protocol (science); Biology; Computer science; Neuroscience; Computational biology; Genetics; Medicine; Gene","score_opus":0.06528307347822136,"score_gpt":0.4165182546242564,"score_spread":0.351235181146035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402944912","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.081271246,0.00009560524,0.08086294,0.00044435152,0.00011401622,0.837001,0.000095749085,0.00003418766,0.00008089347],"genre_scores_gemma":[0.2622546,6.3701594e-7,0.00044946172,0.00006237915,0.0004892162,0.736648,0.000027655036,0.000021633632,0.000046382305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913764,0.00004972555,0.00022900783,0.0002925003,0.00012433306,0.00016677652],"domain_scores_gemma":[0.9994315,0.00008283458,0.000037635673,0.0003512823,0.000057798206,0.00003895087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002651392,0.00012802222,0.000100175435,0.000017493097,0.00016227637,0.000072786934,0.00015419786,0.00008295756,0.00001967484],"category_scores_gemma":[0.00009961286,0.00007629046,0.000065705775,0.00007553952,0.000107485335,0.0000023330063,0.00008961159,0.00012607432,9.806088e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006336072,0.00004920889,0.00012200813,0.00012882144,0.00004875721,9.876038e-7,0.00023063093,0.00090720964,0.99062806,0.00034304944,0.0059075863,0.0015703314],"study_design_scores_gemma":[0.0008491909,0.0006036898,0.0020133173,0.00009443667,0.000037775102,0.0000043258833,0.00009614393,0.027674707,0.8035679,0.000082551545,0.16481714,0.00015883452],"about_ca_topic_score_codex":0.000022022426,"about_ca_topic_score_gemma":0.000025345722,"teacher_disagreement_score":0.18706016,"about_ca_system_score_codex":0.0000065262175,"about_ca_system_score_gemma":0.000053349257,"threshold_uncertainty_score":0.31110346},"labels":[],"label_agreement":null},{"id":"W4402969161","doi":"10.1016/j.omtn.2024.102349","title":"Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Domaine d’Intérêt Majeur Logiciels et Systèmes Complexes; Sorbonne Université; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; AFM-Téléthon; Association Française contre les Myopathies; Agence Nationale de la Recherche; Fondation Voir et Entendre; Foundation Fighting Blindness","keywords":"Cas9; CRISPR; Genome editing; Computational biology; Guide RNA; Computer science; RNA; Base (topology); Retina; Genome; Biology; Genetics; Gene; Neuroscience","score_opus":0.01028850280644513,"score_gpt":0.2708784636405886,"score_spread":0.2605899608341435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402969161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857402,0.008918841,0.0035680193,0.0002639884,0.0002488432,0.00038720667,0.000037324433,0.000023629702,0.00081195513],"genre_scores_gemma":[0.9964682,0.0006056208,0.0014994517,0.00022253272,0.00091415236,0.00004451619,0.000050762057,0.000043647597,0.0001511374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891114,0.00009250219,0.00025225832,0.00033070057,0.00017058878,0.00024282614],"domain_scores_gemma":[0.999528,0.0000231161,0.000036041532,0.00032768972,0.000040584604,0.000044556993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037314583,0.00018930573,0.00017147751,0.000066748384,0.000048534792,0.000049959654,0.00022279033,0.00010885717,0.000038114205],"category_scores_gemma":[0.000046004596,0.00013609942,0.00008375312,0.00016197105,0.000082438986,0.0000049277764,0.000075032855,0.00011358041,0.0000024540084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058013262,0.00002599604,0.00003820885,0.00007695538,0.00005321881,0.000076416334,0.0002627447,0.00014449579,0.99386346,0.00002491661,0.001224807,0.0041507585],"study_design_scores_gemma":[0.00049371686,0.0004031897,0.00063828623,0.00009374092,0.000017566666,0.000041103747,0.00036244583,0.0007078258,0.78988236,0.000027635948,0.2070817,0.0002504065],"about_ca_topic_score_codex":0.000057064215,"about_ca_topic_score_gemma":0.000016446902,"teacher_disagreement_score":0.20585689,"about_ca_system_score_codex":0.000012611776,"about_ca_system_score_gemma":0.000046011148,"threshold_uncertainty_score":0.5549973},"labels":[],"label_agreement":null},{"id":"W4402970108","doi":"10.1146/annurev-pharmtox-031524-021631","title":"Genetically Enriched Clinical Trials for Precision Development of Noncancer Therapeutics: A Scoping Review","year":2024,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Drug development; Clinical trial; MEDLINE; Cochrane Library; Population; Disease; Intensive care medicine; Meta-analysis; Drug; Pharmacology; Internal medicine; Biology; Environmental health","score_opus":0.1570616094300459,"score_gpt":0.5753460924345787,"score_spread":0.4182844830045328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402970108","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000010846409,0.99229103,0.0018079042,0.00026734784,0.0007778534,0.00469451,0.00009859312,0.000006481382,0.000045458342],"genre_scores_gemma":[0.000013318219,0.9952845,0.001306267,0.0018320838,0.00043660452,0.00092746754,0.0000873828,0.000041939096,0.000070438684],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99466336,0.001525,0.0028792825,0.0005266941,0.000117551266,0.0002880944],"domain_scores_gemma":[0.9971826,0.0012323837,0.00095846993,0.0003221222,0.0002326506,0.00007175551],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008258858,0.00039626897,0.0034330757,0.0000623225,0.000051522202,0.000003875312,0.0004621349,0.0004571876,0.00006465623],"category_scores_gemma":[0.0008870874,0.00023631929,0.00087511085,0.00014995804,0.0002580917,0.0000024372873,0.00033197086,0.00031703984,0.000005655535],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038432572,0.000047128204,1.2602699e-7,0.32171774,0.0008043628,6.440946e-7,0.00001777788,2.1108457e-7,0.000549435,0.000016869359,0.0038076676,0.6729996],"study_design_scores_gemma":[0.00028103622,0.0005069558,7.213823e-7,0.18516292,0.0065240907,0.00002495205,0.0000036682607,0.000001985984,0.0005451823,0.000013653821,0.8067397,0.00019513274],"about_ca_topic_score_codex":2.0994365e-7,"about_ca_topic_score_gemma":0.0000022135164,"teacher_disagreement_score":0.802932,"about_ca_system_score_codex":0.000013073276,"about_ca_system_score_gemma":0.000935464,"threshold_uncertainty_score":0.96368206},"labels":[],"label_agreement":null},{"id":"W4402992229","doi":"10.1038/s41598-024-72418-8","title":"Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; SickKids Foundation; University of Manitoba; Toronto Centre for Phenogenomics; Hospital for Sick Children","funders":"NIH Office of the Director; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences; European Regional Development Fund; Medical Research Council; PHENOMIN; Common Fund; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale; European Molecular Biology Laboratory; Akademie Věd České Republiky; Centre National de la Recherche Scientifique; Ministerstvo Školství, Mládeže a Tělovýchovy; National Human Genome Research Institute; Wellcome Trust; Agence Nationale de la Recherche; Genome Canada; National Institutes of Health; Ontario Genomics; Univerzita Karlova v Praze","keywords":"Genetically engineered; Genome editing; Gene; Genome; Genetically modified organism; Computational biology; Biology; Genetics","score_opus":0.010979396851233874,"score_gpt":0.31415786343819785,"score_spread":0.30317846658696396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402992229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98108125,0.0034930268,0.013009341,0.000025364945,0.0020866522,0.00018058073,0.000011473505,0.00001888876,0.00009344228],"genre_scores_gemma":[0.9969107,0.0000345238,0.0013733697,0.000004638609,0.00072788226,0.000010006311,0.0000798785,0.000029376872,0.00082962686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984294,0.00002411499,0.0004994016,0.0004906939,0.00030765779,0.00024873306],"domain_scores_gemma":[0.9990303,0.000018585431,0.00011975463,0.00061487174,0.00012478685,0.00009173482],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044008132,0.00017629439,0.00016970151,0.00009822163,0.00007945372,0.00011956389,0.00018246628,0.00008072958,0.00006804475],"category_scores_gemma":[0.000121218465,0.00012636339,0.00021438362,0.00021919284,0.0001067141,0.0000056575877,0.000108795815,0.000070443115,0.0000013996948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005869732,0.000026764306,0.00037065413,0.00003691264,0.00008764445,0.000014368201,0.00013725835,0.05019671,0.9470484,0.000013531057,0.001142371,0.0009195002],"study_design_scores_gemma":[0.000060512168,0.00009687633,0.0003449406,0.00003599265,0.000020372216,0.000034626908,0.000033293272,0.005450128,0.9927988,0.00002140211,0.0009766239,0.00012639764],"about_ca_topic_score_codex":0.000039165065,"about_ca_topic_score_gemma":0.000005281488,"teacher_disagreement_score":0.04575042,"about_ca_system_score_codex":0.000012899016,"about_ca_system_score_gemma":0.00019291246,"threshold_uncertainty_score":0.5152949},"labels":[],"label_agreement":null},{"id":"W4403113711","doi":"10.1080/17460794.2024.2403253","title":"Potential use of <i>CRISPR/Cas13</i> system for vaccine development against various RNA-viral infections","year":2024,"lang":"en","type":"article","venue":"Future Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Virology; Biology; Computational biology; Genetics; Gene","score_opus":0.004270226493919845,"score_gpt":0.24760726958438323,"score_spread":0.2433370430904634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403113711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.66120183,0.00297568,0.33219838,0.00018607383,0.0029048785,0.0002969582,0.00006121112,0.000066004424,0.00010897461],"genre_scores_gemma":[0.9947563,0.00014835993,0.003237018,0.00011788187,0.0011914329,0.000059977585,0.00018701202,0.000033199733,0.00026884765],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99912447,0.000024198907,0.00025708502,0.00029857716,0.00005992084,0.00023575078],"domain_scores_gemma":[0.9996281,0.000016102134,0.000036369034,0.00021043551,0.00005461926,0.00005434065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092907874,0.00015846352,0.00017650593,0.00008612655,0.00006417786,0.000020244444,0.00009273557,0.00023480818,0.000005401572],"category_scores_gemma":[0.000016658048,0.00014681857,0.000114325645,0.00007771743,0.000017577368,0.0000039423107,0.000069080765,0.00009800544,0.0000058675582],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009142809,0.000049821858,0.00016126112,0.0002578165,0.00022962879,0.000015003482,0.00009274075,0.005227167,0.9789184,0.00042753672,0.0046412544,0.009887965],"study_design_scores_gemma":[0.0005352334,0.00037504165,0.0014060098,0.000024252322,0.00007509658,0.000095092495,0.000042801596,0.0014102526,0.33456308,0.000008294017,0.6612488,0.0002160867],"about_ca_topic_score_codex":0.0000072458106,"about_ca_topic_score_gemma":0.00003408959,"teacher_disagreement_score":0.6566075,"about_ca_system_score_codex":0.000018602483,"about_ca_system_score_gemma":0.000072800955,"threshold_uncertainty_score":0.59870875},"labels":[],"label_agreement":null},{"id":"W4403136517","doi":"10.3390/cells13191653","title":"Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Canadian Institutes of Health Research; China Postdoctoral Science Foundation; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"CRISPR; Gene; Computational biology; Biology; Small hairpin RNA; Genetics; Bioinformatics; RNA","score_opus":0.017422862517098917,"score_gpt":0.35484250826563296,"score_spread":0.33741964574853406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403136517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59241635,0.005486094,0.40181422,0.0000077749355,0.00009155241,0.00014556981,0.0000058812752,0.000013197285,0.000019379855],"genre_scores_gemma":[0.9948675,0.000047358168,0.0049002846,0.000016231988,0.000056028246,0.000007608225,0.00001348333,0.000026131383,0.00006537037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917644,0.000033927063,0.00026082492,0.00025424178,0.00011368922,0.00016085482],"domain_scores_gemma":[0.999658,0.00001682054,0.000031707707,0.00017324336,0.000044460816,0.00007576151],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013937913,0.0001309622,0.00022271655,0.00009868314,0.0000443168,0.000049388298,0.0000908677,0.00007986729,0.0000043824953],"category_scores_gemma":[0.000018029605,0.0001289858,0.00008646736,0.00011200266,0.000028021856,0.0000025456786,0.00006407391,0.00006791435,0.0000026421885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007212601,0.000010802409,0.00012243896,0.0028437418,0.000037062848,0.0000013664146,0.00011032266,0.28251958,0.71422255,0.000006174696,0.000044145854,0.00007463379],"study_design_scores_gemma":[0.00009143312,0.000041617677,0.000025358046,0.0004618293,0.00006672022,0.0000017510037,0.00011214242,0.41458413,0.58448577,0.0000045912916,0.000028179193,0.000096497795],"about_ca_topic_score_codex":0.000019854571,"about_ca_topic_score_gemma":0.0000066338125,"teacher_disagreement_score":0.4024512,"about_ca_system_score_codex":0.000005678485,"about_ca_system_score_gemma":0.000032983386,"threshold_uncertainty_score":0.5259889},"labels":[],"label_agreement":null},{"id":"W4403235061","doi":"10.1111/febs.17295","title":"Biochemical plasticity of the <i>Escherichia coli</i><scp>CRISPR</scp> Cascade revealed by <i>in vitro</i> reconstitution of Cascade activities from purified Cas proteins","year":2024,"lang":"en","type":"article","venue":"FEBS Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"U.S. National Library of Medicine; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Toronto","keywords":"Trans-activating crRNA; CRISPR; Effector; Nuclease; Biology; DNA; RNA; Escherichia coli; Cell biology; Molecular biology; Cas9; Chemistry; Biochemistry; Gene","score_opus":0.006581065891873058,"score_gpt":0.2504167453560889,"score_spread":0.24383567946421583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403235061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848567,0.005460195,0.008464387,0.000075643584,0.00047182236,0.00019665217,0.00020479645,0.000008295525,0.00026150228],"genre_scores_gemma":[0.9982798,0.0004054955,0.00075040804,0.000040432464,0.00027262367,0.000012951471,0.000023438606,0.000020373256,0.00019448689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998842,0.000078037105,0.00040059275,0.00023148001,0.00019778796,0.00025008054],"domain_scores_gemma":[0.99950594,0.00006994082,0.00012597744,0.00017279715,0.000042681255,0.0000826368],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001841206,0.00017454609,0.00023979838,0.00005353395,0.00005647394,0.000032713262,0.00022122292,0.00021654536,0.0000071756576],"category_scores_gemma":[0.0002095389,0.0001392078,0.00016715826,0.00016421622,0.00014363017,0.000009755151,0.00007545843,0.00042775224,9.589126e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049360824,0.000049205806,0.0003733571,0.000069846166,0.00008051264,0.000008845391,0.00018729978,0.000255535,0.9935515,0.000008440769,0.0051465333,0.00021957375],"study_design_scores_gemma":[0.00039093467,0.000068597576,0.001449725,0.00016724471,0.000047891772,0.000081730555,0.00015566166,0.00028364232,0.99012214,0.000044676595,0.007111631,0.000076113916],"about_ca_topic_score_codex":0.0001120835,"about_ca_topic_score_gemma":0.000030754145,"teacher_disagreement_score":0.013423084,"about_ca_system_score_codex":0.000040789713,"about_ca_system_score_gemma":0.00018916737,"threshold_uncertainty_score":0.56767297},"labels":[],"label_agreement":null},{"id":"W4403342765","doi":"10.1016/b978-0-443-19041-4.00021-2","title":"CRISPR/Cas9-based genetic engineering for translational research in neurological disorders","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"CRISPR; Translational research; Computational biology; Biology; Computer science; Medicine; Genetics; Biotechnology; Gene","score_opus":0.022322769571078628,"score_gpt":0.3256891397171052,"score_spread":0.3033663701460266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403342765","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0069905594,0.03184866,0.012506568,0.0011404199,0.0016091795,0.004061798,0.00036063546,0.0001529924,0.9413292],"genre_scores_gemma":[0.24969386,0.0005288864,0.0056575146,0.0002476583,0.001651438,0.00068181474,0.0004261026,0.00044746543,0.74066526],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99842215,0.000015857517,0.00033262526,0.00056693994,0.000244289,0.00041811753],"domain_scores_gemma":[0.9994034,0.00008047515,0.00002657361,0.00033888218,0.00005741079,0.00009321223],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028996877,0.00032722487,0.00025754437,0.00033539644,0.00004437705,0.000034763492,0.0002347573,0.00047088374,0.000024038995],"category_scores_gemma":[0.000024063518,0.0003384267,0.00024914535,0.000031874646,0.000076344324,8.9317217e-7,0.00006951607,0.00050475664,0.000015530284],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020941466,0.000040458628,0.00011021595,0.0011681722,0.00017297962,0.000053604283,0.00010545799,0.02300567,0.011418784,0.0050857756,0.00034586573,0.9582836],"study_design_scores_gemma":[0.0004190241,0.0002923646,0.000141052,0.0001513261,0.000036968984,0.0000077094455,0.0000022819022,0.00471499,0.0009333655,0.0041525043,0.9887348,0.000413623],"about_ca_topic_score_codex":3.4274748e-7,"about_ca_topic_score_gemma":0.000040100174,"teacher_disagreement_score":0.9883889,"about_ca_system_score_codex":0.000012984713,"about_ca_system_score_gemma":0.00010288731,"threshold_uncertainty_score":0.9999068},"labels":[],"label_agreement":null},{"id":"W4403356562","doi":"10.1101/2024.10.09.617463","title":"Tunable, proteolytic dosage control of CRISPR-Cas systems enables precise gene therapy for dosage sensitive disorders","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"CRISPR; Gene dosage; Haploinsufficiency; Gene; Gene expression; Genetic enhancement; Gene delivery; Cleavage (geology); Biology; RNA; Cell biology; Computational biology; Genetics","score_opus":0.006617792886842119,"score_gpt":0.24190918634561215,"score_spread":0.23529139345877004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403356562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68315107,0.0362316,0.2701142,0.00014741284,0.002095685,0.005906987,0.0021375518,0.00019600765,0.000019507203],"genre_scores_gemma":[0.9936855,0.0018617312,0.0020749862,0.000045156525,0.00074115844,0.0013147583,0.0000051468605,0.0002351567,0.000036433656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971255,0.00011303056,0.000621389,0.0012047291,0.00028864396,0.00064669666],"domain_scores_gemma":[0.997757,0.00005942172,0.0003167085,0.0012098466,0.0004537314,0.00020327333],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000607649,0.00071632495,0.00076893123,0.00020739458,0.00009458189,0.0001496058,0.000434316,0.000716662,0.0000050070935],"category_scores_gemma":[0.00016075886,0.00071866525,0.00038687402,0.00022109899,0.0001260624,0.000006783674,0.0002910816,0.0004136798,0.0000065519725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021848193,0.00010883371,0.00020853803,0.00162365,0.0007089101,0.000013349972,0.000019507585,0.005054258,0.9916044,0.00009169297,0.0003361002,0.000012309725],"study_design_scores_gemma":[0.0013919221,0.0002970015,0.0017257547,0.00044083688,0.00022630132,8.650072e-8,0.000014284728,0.0038854647,0.9872142,0.0000049315254,0.004000022,0.0007992027],"about_ca_topic_score_codex":0.000080966536,"about_ca_topic_score_gemma":0.000005287651,"teacher_disagreement_score":0.31053442,"about_ca_system_score_codex":0.00007971182,"about_ca_system_score_gemma":0.00045647894,"threshold_uncertainty_score":0.99952644},"labels":[],"label_agreement":null},{"id":"W4403489647","doi":"10.51731/cjht.2024.999","title":"CRISPR Technologies for In Vivo and Ex Vivo Gene Editing","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Ex vivo; Genome editing; Biology; In vivo; Gene; Genetics; Computational biology","score_opus":0.011123602297740065,"score_gpt":0.3030946579556271,"score_spread":0.29197105565788706,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403489647","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41733214,0.5333783,0.02854811,0.018867295,0.0010644859,0.00042717357,0.00009386587,0.00018040036,0.000108208114],"genre_scores_gemma":[0.99377894,0.0027104842,0.0033355942,0.000060968083,0.00004274619,0.000011845087,0.0000018677906,0.000018439738,0.00003913129],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990306,0.000010018647,0.00034671655,0.00018226352,0.00005142501,0.00037899354],"domain_scores_gemma":[0.99965876,0.000022842929,0.00007351582,0.00015280914,0.000052261326,0.0000397793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040489665,0.00012087693,0.0002024181,0.00045908935,0.00007636072,0.00004482562,0.00020808697,0.00021020416,0.000002197222],"category_scores_gemma":[0.00042084395,0.000111969275,0.000050331244,0.00016847298,0.00011742581,0.0000069782627,0.000036229612,0.00021229303,2.8014637e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021457965,0.000013996346,0.0039386754,0.00079991465,0.00009892147,0.00016934738,0.00035161723,0.00030754315,0.20670733,0.0014284496,0.026174562,0.7599882],"study_design_scores_gemma":[0.00033325874,0.0005244375,0.000373102,0.00033598684,0.000010701053,0.00038210195,0.0047980705,0.00017479967,0.50983167,0.0023308126,0.4806806,0.00022443598],"about_ca_topic_score_codex":0.0002510226,"about_ca_topic_score_gemma":0.0018858234,"teacher_disagreement_score":0.7597638,"about_ca_system_score_codex":0.00006572525,"about_ca_system_score_gemma":0.0004930068,"threshold_uncertainty_score":0.45659745},"labels":[],"label_agreement":null},{"id":"W4403507865","doi":"10.1016/j.tibtech.2024.09.019","title":"Gene editing technology: shaping international standards for health and food safety assurance","year":2024,"lang":"en","type":"review","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Ste. Anne's Hospital","funders":"","keywords":"CRISPR; Genome editing; Food safety; Ethical issues; Engineering ethics; Cas9; Biosafety; Ethical standards; Gene technology; Emerging technologies; Biotechnology; Business; Risk analysis (engineering); Biology; Engineering; Computer science; Gene; Genetics; Food science","score_opus":0.027495024809346926,"score_gpt":0.4024244054351957,"score_spread":0.3749293806258488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403507865","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002531797,0.98802096,0.008098924,0.0017158559,0.0007394571,0.00027041158,0.0009089217,0.00011483399,0.000105323554],"genre_scores_gemma":[0.0004848576,0.99324775,0.0049659233,0.000042977143,0.00032297417,0.00015615665,0.0005816386,0.00007142534,0.00012631295],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99814427,0.000020133426,0.0005667298,0.0007468557,0.00010716162,0.00041487455],"domain_scores_gemma":[0.99937063,0.000016807708,0.00015739787,0.0003676723,0.000036328187,0.000051144776],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003524689,0.00036707133,0.00080595224,0.0010187573,0.000054746844,0.000023181748,0.00038153786,0.0011740753,0.0000043503155],"category_scores_gemma":[0.00013776204,0.00034874456,0.00017371685,0.0004952926,0.00013391866,0.000002227166,0.0003543191,0.0004841202,0.0000011406731],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000066239463,0.0000110211995,0.0000036352965,0.0022572472,0.00016946839,0.0000027364158,0.000008528691,0.0000040874106,0.00012165744,0.00048575382,0.0012586679,0.99567056],"study_design_scores_gemma":[0.00027977748,0.0003390217,8.639829e-7,0.0021083269,0.000060796425,0.00013246549,0.000021417838,0.00004686865,0.0007022193,0.00010987521,0.99591714,0.00028122406],"about_ca_topic_score_codex":0.0000016728961,"about_ca_topic_score_gemma":0.00006958176,"teacher_disagreement_score":0.99538934,"about_ca_system_score_codex":0.000121746736,"about_ca_system_score_gemma":0.00021615975,"threshold_uncertainty_score":0.99989647},"labels":[],"label_agreement":null},{"id":"W4403548299","doi":"10.1016/j.lfs.2024.123120","title":"CRISPR innovations in tissue engineering and gene editing","year":2024,"lang":"en","type":"review","venue":"Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"CRISPR; Genome editing; Computational biology; Gene; Biology; Computer science; Genetics","score_opus":0.026039234260030596,"score_gpt":0.3789683852541938,"score_spread":0.3529291509941632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403548299","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022263863,0.9978957,0.0010010961,0.000033207896,0.00048029717,0.00013083774,0.000013036012,0.000014806611,0.00020834523],"genre_scores_gemma":[0.00054515805,0.996887,0.0016928212,0.000021302218,0.0006402169,0.000032739845,0.000028420176,0.000018776056,0.00013353117],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99906945,0.000010911637,0.00025706613,0.00036848782,0.00009311846,0.00020097921],"domain_scores_gemma":[0.99976707,0.0000142114395,0.00003685454,0.000118388176,0.000012847241,0.000050605406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025982579,0.00017730756,0.00028191772,0.00020383294,0.000041876265,0.00005245941,0.00016873807,0.00013106261,0.0000041147186],"category_scores_gemma":[0.00015171841,0.00014875132,0.000043796434,0.0005197285,0.000054056865,0.000003043745,0.00014147293,0.0001364079,0.000008897055],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[7.951345e-7,0.000027010161,0.000055883826,0.014380009,0.00011136106,0.000028468789,0.00014563093,0.001606755,0.0072816876,0.0007476296,0.005758251,0.9698565],"study_design_scores_gemma":[0.000024053177,0.00003069278,0.0000056863105,0.001039925,0.000042626274,0.000025572801,0.00001867602,0.00020853928,0.00054983946,0.0000073180167,0.9978633,0.00018375204],"about_ca_topic_score_codex":0.0000077137165,"about_ca_topic_score_gemma":0.000008030084,"teacher_disagreement_score":0.99210507,"about_ca_system_score_codex":0.000007062591,"about_ca_system_score_gemma":0.000112608344,"threshold_uncertainty_score":0.6065903},"labels":[],"label_agreement":null},{"id":"W4403548360","doi":"10.1039/d4cc04534c","title":"CRISPR/Cas12a assay for amol level microRNA by combining enzyme-free amplification and single particle analysis","year":2024,"lang":"en","type":"article","venue":"Chemical Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Outstanding Youth Science and Technology Talents Program of Sichuan; Fundamental Research Funds for the Central Universities; Sichuan Province Science and Technology Support Program; Chengdu Science and Technology Bureau; National Natural Science Foundation of China","keywords":"CRISPR; Chemistry; Molecular biology; Computational biology; Biology; Biochemistry; Gene","score_opus":0.03950702468401947,"score_gpt":0.33686791601437077,"score_spread":0.2973608913303513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403548360","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.39739838,0.023073165,0.57420874,0.0038679505,0.00006721656,0.0003390592,0.00040342537,0.000094857256,0.00054722],"genre_scores_gemma":[0.9878722,0.0002504154,0.010515366,0.000088148394,0.00003543173,0.00009217002,0.0008514359,0.000020312602,0.00027455445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993081,0.000027322661,0.0001980167,0.00025099207,0.000055725224,0.00015985596],"domain_scores_gemma":[0.9987139,0.00012647745,0.000028155038,0.0009966625,0.00005874141,0.000076037744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017291305,0.000106035266,0.00012009081,0.000033579603,0.00009797281,0.000075111835,0.00040148574,0.0000954718,0.0000041346343],"category_scores_gemma":[0.00018934307,0.000113799426,0.00009552656,0.0002086384,0.00009887555,0.0000052688256,0.00025516673,0.00009529274,0.0000025983427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000053738536,0.00005423721,0.0001517374,0.000021695163,0.00015555395,5.9784995e-8,0.00007742141,0.000018121844,0.9897178,0.00043123576,0.0074762176,0.001890565],"study_design_scores_gemma":[0.00019981216,0.000029620154,0.00012893208,0.0000109167095,0.00021242478,0.000002803628,0.00006706036,0.009607929,0.93349785,0.00022370393,0.055869415,0.00014951263],"about_ca_topic_score_codex":0.000013159731,"about_ca_topic_score_gemma":0.000019282714,"teacher_disagreement_score":0.5904738,"about_ca_system_score_codex":0.00001699126,"about_ca_system_score_gemma":0.000016061033,"threshold_uncertainty_score":0.46406057},"labels":[],"label_agreement":null},{"id":"W4403565223","doi":"10.1016/j.xpro.2024.103404","title":"Protocol for CRISPR-based endogenous protein tagging in mammalian cells","year":2024,"lang":"en","type":"article","venue":"STAR Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto; GlaxoSmithKline","keywords":"CRISPR; Endogeny; Protocol (science); Computational biology; Computer science; Biology; Genetics; Gene; Biochemistry; Medicine","score_opus":0.03500666988375374,"score_gpt":0.37305969258603267,"score_spread":0.33805302270227894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403565223","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017022552,0.000023991015,0.026428817,0.00012662746,0.00004224936,0.97107625,0.00005014446,0.00006960578,0.00048008634],"genre_scores_gemma":[0.03591928,8.6070294e-8,0.007869643,0.00007347794,0.00021297498,0.95546895,0.000024599958,0.00006185739,0.00036915133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986755,0.00003685515,0.00028654374,0.0004614668,0.00012537543,0.00041424588],"domain_scores_gemma":[0.9995064,0.000012229261,0.000033001274,0.00032822238,0.00004324417,0.000076861295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002744384,0.00021833005,0.0001550044,0.000096373566,0.00004804277,0.000083461244,0.00019109984,0.00013474812,0.000045108045],"category_scores_gemma":[0.000031932694,0.0002076159,0.00011585522,0.00013255852,0.00002817992,0.0000043555847,0.00004677919,0.000119950186,0.000012478002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020084286,0.000073029776,0.000028188544,0.0014761053,0.000014265736,0.000020565194,0.000043265598,0.0007960565,0.9927747,0.00008681448,0.0012782855,0.0032078736],"study_design_scores_gemma":[0.00091351493,0.00041061532,0.0000114839895,0.00022757477,0.000002735204,0.0000028152115,0.000010068615,0.0010296638,0.6288468,0.000067435525,0.36830065,0.00017662813],"about_ca_topic_score_codex":0.0000180223,"about_ca_topic_score_gemma":0.000031383075,"teacher_disagreement_score":0.36702237,"about_ca_system_score_codex":0.00003370125,"about_ca_system_score_gemma":0.00019620435,"threshold_uncertainty_score":0.8466331},"labels":[],"label_agreement":null},{"id":"W4403571478","doi":"10.1101/2024.10.18.619117","title":"Packaged delivery of CRISPR-Cas9 ribonucleoproteins accelerates genome editing","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Science Foundation","keywords":"CRISPR; Ribonucleoprotein; Genome editing; Cas9; Computational biology; Computer science; Biology; Genetics; Gene; RNA","score_opus":0.009419738037540516,"score_gpt":0.24253707083601536,"score_spread":0.23311733279847485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403571478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98319274,0.010818818,0.0033829683,0.00009497137,0.0013017195,0.0005456532,0.00046981953,0.00015631517,0.000036997877],"genre_scores_gemma":[0.9933257,0.0008592003,0.0037249692,0.00006783388,0.0016820295,0.00011927981,0.000003709376,0.00020225218,0.000015009469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99737364,0.00006779897,0.0006278349,0.0010638692,0.00029996238,0.0005669215],"domain_scores_gemma":[0.997837,0.000017540631,0.00026096514,0.0012170424,0.00045395654,0.00021346213],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041954935,0.0006055804,0.00053999544,0.0002168672,0.000092329814,0.00015846755,0.00058068195,0.00069905305,0.00003408969],"category_scores_gemma":[0.00015675233,0.00067458395,0.00029986503,0.00027141743,0.00011977412,0.000006821484,0.0013358814,0.0007216467,0.000040575465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019610805,0.00005533141,0.0005835605,0.0009197043,0.00028322492,0.000031684383,0.000009792354,0.00055033,0.99703497,0.000059228645,0.00044755786,0.0000050222434],"study_design_scores_gemma":[0.0002534259,0.0000964412,0.0076809647,0.00031389302,0.00014829957,5.4750757e-8,0.000008328067,0.0002769192,0.98501176,0.000003895889,0.005534079,0.0006719276],"about_ca_topic_score_codex":0.000048593585,"about_ca_topic_score_gemma":0.0000047203453,"teacher_disagreement_score":0.012023182,"about_ca_system_score_codex":0.000064405875,"about_ca_system_score_gemma":0.00035156898,"threshold_uncertainty_score":0.99957055},"labels":[],"label_agreement":null},{"id":"W4403680322","doi":"10.1038/s41586-024-08088-3","title":"Nuclear release of eIF1 restricts start-codon selection during mitosis","year":2024,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Mitosis; Selection (genetic algorithm); Biology; Cell biology; Evolutionary biology; Computer science","score_opus":0.002775954753797847,"score_gpt":0.2563029136368851,"score_spread":0.2535269588830873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403680322","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99290293,0.005924086,0.00018663003,0.00011921953,0.00027284725,0.00006144217,0.000009985907,0.00003421387,0.0004886557],"genre_scores_gemma":[0.9984257,0.0003567392,0.00040639084,0.00004029032,0.00027963865,0.0000021591443,0.000018861207,0.000022995624,0.0004472318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949914,0.000010115901,0.00009148836,0.00019311013,0.00008891291,0.00011720611],"domain_scores_gemma":[0.99978244,0.000004657735,0.0000143395555,0.00012751069,0.00003333974,0.00003772079],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003835579,0.00008181955,0.00006512747,0.000053692882,0.000027900978,0.000014671477,0.00006647838,0.0005007568,0.00001764599],"category_scores_gemma":[0.000042300064,0.000080047925,0.00006258124,0.00014824203,0.000010803061,0.0000022566205,0.000031825817,0.0003674212,0.0000040068303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033341563,0.000011012123,0.00025481835,0.00011955102,0.000032502492,0.000004285096,0.000031063635,0.00038997422,0.9931424,0.000056523582,0.004892555,0.0010319205],"study_design_scores_gemma":[0.00013056918,0.00008673976,0.003801895,0.00004427942,0.00001996863,0.000017143124,0.000020453064,0.00043954578,0.93040836,0.000013169275,0.0649138,0.00010408477],"about_ca_topic_score_codex":0.00000606448,"about_ca_topic_score_gemma":0.000008500894,"teacher_disagreement_score":0.062734105,"about_ca_system_score_codex":0.000010351337,"about_ca_system_score_gemma":0.000020422582,"threshold_uncertainty_score":0.3862295},"labels":[],"label_agreement":null},{"id":"W4403718841","doi":"10.1126/science.adi6884","title":"Impact of CRISPR in cancer drug discovery","year":2024,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"CRISPR; Identification (biology); Computational biology; Drug discovery; Massively parallel; Gene; Cancer drugs; Cancer; Drug; Biology; Massive parallel sequencing; Genetics; Computer science; Bioinformatics; Genome; Pharmacology","score_opus":0.006698729458096745,"score_gpt":0.37633583446382607,"score_spread":0.3696371050057293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403718841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99340504,0.004092555,0.0019496694,0.000028440405,0.0001850498,0.000030672363,0.000008623107,0.000003500865,0.000296428],"genre_scores_gemma":[0.99936926,0.00018834625,0.00007628193,0.000006606533,0.000042316962,0.0000035336734,0.0000010916945,0.000003575509,0.0003090041],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995722,0.000002969006,0.00006258913,0.00016191498,0.0000765948,0.0001237438],"domain_scores_gemma":[0.99983853,0.0000030791018,0.0000060914617,0.00011281638,0.000014530119,0.000024962841],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012723639,0.000042515072,0.0000404024,0.00005606501,0.000011053323,0.000024398541,0.00012396036,0.00001368657,0.000008770135],"category_scores_gemma":[0.000020168369,0.00003344179,0.000035364865,0.00025394314,0.00008989227,0.000006189743,0.000049990547,0.0000297016,0.0000012620642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000026461616,0.0000067654087,0.011207388,0.000012736904,0.0000029763487,0.0000010933395,0.0000797505,0.0032827016,0.9830086,0.000026217062,0.00019129764,0.0021777789],"study_design_scores_gemma":[0.000058185244,0.000051036004,0.15843885,0.00004042809,0.0000023506047,0.0000026102118,0.000029182227,0.001510644,0.838798,0.00004547657,0.00094317034,0.00008009485],"about_ca_topic_score_codex":0.0001528068,"about_ca_topic_score_gemma":0.00006806246,"teacher_disagreement_score":0.14723146,"about_ca_system_score_codex":0.000018082883,"about_ca_system_score_gemma":0.0001910901,"threshold_uncertainty_score":0.13637166},"labels":[],"label_agreement":null},{"id":"W4403776172","doi":"10.1051/medsci/2024109","title":"La correction de mutations pathogènes par <i>Prime editing</i>","year":2024,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"Molecular biology; Biology","score_opus":0.01866141328463652,"score_gpt":0.3551094712074164,"score_spread":0.33644805792277993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403776172","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019318548,0.9713702,0.012150278,0.00028790173,0.0054673627,0.00029441694,0.0000767514,0.000053243646,0.00836797],"genre_scores_gemma":[0.049970403,0.9388362,0.0025973534,0.00011917665,0.003960282,0.00012071144,0.00018716276,0.000072513096,0.00413621],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976979,0.00021235905,0.0004873384,0.0008064846,0.00025351762,0.0005424215],"domain_scores_gemma":[0.9992435,0.000147736,0.00014920534,0.0002611241,0.00005942733,0.00013900617],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000992891,0.00045802875,0.00049913686,0.00015949746,0.00035307807,0.00021542338,0.00042852713,0.00047635546,0.00006788744],"category_scores_gemma":[0.0003261782,0.0003960118,0.0003828014,0.0006165495,0.000613192,0.00000816005,0.00017696062,0.0003797429,0.00016470865],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000058490177,0.0002528454,0.0010120659,0.0059168846,0.0003072475,0.000084287734,0.0003931919,0.004138434,0.013245205,0.0010651188,0.054346994,0.9192319],"study_design_scores_gemma":[0.00013141015,0.00030469807,0.000104002596,0.0026190823,0.0005916223,0.00047466246,0.0002623961,0.0012704473,0.003930414,0.00019021606,0.9896322,0.00048888766],"about_ca_topic_score_codex":0.000046054753,"about_ca_topic_score_gemma":0.000041289437,"teacher_disagreement_score":0.93528515,"about_ca_system_score_codex":0.000053359756,"about_ca_system_score_gemma":0.0005708791,"threshold_uncertainty_score":0.9998492},"labels":[],"label_agreement":null},{"id":"W4403983361","doi":"10.1016/b978-0-443-23826-0.00006-4","title":"Epigenetic manipulation and gene regulation using the CRISPR/Cas system for neurodegenerative diseases","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trent University","funders":"","keywords":"CRISPR; Epigenetics; Computational biology; Biology; Gene; Genetics","score_opus":0.016212907661256593,"score_gpt":0.28283023960024134,"score_spread":0.26661733193898474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403983361","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04537781,0.2354433,0.1755393,0.00040605877,0.007819017,0.012821107,0.0019149883,0.0004199809,0.5202584],"genre_scores_gemma":[0.40347105,0.00031381627,0.0013061861,0.00007856901,0.002190464,0.00012774476,0.00041964147,0.00023127538,0.59186125],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989014,0.000016884236,0.00028068887,0.00049640145,0.00012701572,0.00017760275],"domain_scores_gemma":[0.9993517,0.000018226761,0.00009990345,0.00037772962,0.000085423366,0.000067063906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000090829984,0.00031670168,0.00022633487,0.00005812962,0.00014932753,0.00007155154,0.00010457536,0.00021232005,0.0000031909233],"category_scores_gemma":[0.000009322731,0.00025877528,0.00015832346,0.000009268301,0.00006424154,0.0000017426042,0.00010470456,0.00009989186,0.0000026213459],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016626311,0.000013033582,0.00003963585,0.0023160474,0.00085259526,0.000021903354,0.00041979202,0.011536011,0.4297895,0.01394879,0.00028395728,0.54061246],"study_design_scores_gemma":[0.00084187876,0.000436347,0.0004330536,0.00087324076,0.0023257008,0.0002286341,0.00008583399,0.023907296,0.23702082,0.005863996,0.72632736,0.0016558422],"about_ca_topic_score_codex":5.3006625e-7,"about_ca_topic_score_gemma":0.000010454984,"teacher_disagreement_score":0.7260434,"about_ca_system_score_codex":0.00003527807,"about_ca_system_score_gemma":0.000043840348,"threshold_uncertainty_score":0.99998647},"labels":[],"label_agreement":null},{"id":"W4404021236","doi":"10.1128/jvi.00832-24","title":"A temperature-sensitive and less immunogenic Sendai virus for efficient gene editing","year":2024,"lang":"en","type":"article","venue":"Journal of Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; European Molecular Biology Organization","keywords":"Genome editing; Biology; Sendai virus; Transduction (biophysics); CRISPR; Gene delivery; Viral vector; Stem cell; Genetic enhancement; Cas9; Hematopoietic stem cell; Computational biology; Haematopoiesis; Virology; Gene; Genetics","score_opus":0.005608549423934808,"score_gpt":0.2836328603440772,"score_spread":0.2780243109201424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404021236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9675732,0.011667046,0.019631477,0.00025011395,0.0007666854,0.00006652255,0.000019982888,0.0000040773903,0.000020862359],"genre_scores_gemma":[0.9970697,0.00041322265,0.0012327933,0.000116526186,0.0010963042,0.0000026655737,0.0000071717063,0.00001650346,0.000045111767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994315,0.000023464636,0.00020222444,0.00013613053,0.00005419027,0.00015251644],"domain_scores_gemma":[0.9997253,0.000031732365,0.000051331066,0.00007195238,0.000071793234,0.000047937017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024389173,0.00009316599,0.00014466823,0.00006314756,0.000038381666,0.00002253473,0.00005486471,0.00011586858,0.0000019206523],"category_scores_gemma":[0.000052738545,0.000079128804,0.000103111146,0.000036463196,0.000039303948,0.000001699686,0.000038026752,0.00012726126,6.5105115e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009104709,0.000013260942,0.000011342813,0.000024682777,0.00011562647,0.000029918918,0.00008837254,0.0019858752,0.9948336,0.000028191842,0.00043664445,0.0023414744],"study_design_scores_gemma":[0.00047665156,0.00058880314,0.00061306235,0.00002569035,0.000065789805,0.0013654713,0.00011843553,0.0018445335,0.98320544,0.000027271963,0.011567711,0.00010114151],"about_ca_topic_score_codex":0.0000015046837,"about_ca_topic_score_gemma":0.0000032603718,"teacher_disagreement_score":0.029496469,"about_ca_system_score_codex":0.000008981345,"about_ca_system_score_gemma":0.00004022585,"threshold_uncertainty_score":0.32267788},"labels":[],"label_agreement":null},{"id":"W4404044890","doi":"10.1177/09636625241287392","title":"Sociotechnical imaginaries of gene editing in food and agriculture: A comparative content analysis of mass media in the United States, New Zealand, Japan, the Netherlands, and Canada","year":2024,"lang":"en","type":"article","venue":"Public Understanding of Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University","funders":"Division of Social and Economic Sciences; National Science Foundation","keywords":"Sociotechnical system; Legitimacy; Narrative; Sociology; Agriculture; Civil society; Public relations; Political science; Political economy; Politics; Economics; Law; Biology; Ecology","score_opus":0.048799362416089245,"score_gpt":0.28788765434738717,"score_spread":0.23908829193129794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404044890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98822033,0.0016085319,0.007913547,0.0020952635,0.000032305135,0.0000758462,0.000026000504,0.0000015603082,0.00002661875],"genre_scores_gemma":[0.9996412,0.00016803805,0.0001284958,0.00002417469,0.000011694585,0.0000016863576,0.000019381223,0.0000016772844,0.000003688794],"study_design_codex":"bench_or_experimental","study_design_gemma":"qualitative","domain_scores_codex":[0.99935216,0.000026261543,0.00016707432,0.00014047348,0.00018473304,0.00012931296],"domain_scores_gemma":[0.9996844,0.00011177027,0.000047476395,0.00008367991,0.000039830084,0.000032826167],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005487733,0.00006112892,0.00013104474,0.00015191597,0.000040947987,0.00003642894,0.00015676685,0.000025894653,6.0732464e-7],"category_scores_gemma":[0.000076099874,0.0000353737,0.000018065282,0.0009648331,0.00060914,0.000007836,0.00004051435,0.00007558308,1.9371946e-9],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044284352,0.00005031608,0.09192382,0.00011644953,0.00048629162,0.000003977833,0.03976287,0.0084446715,0.8448832,0.012089999,0.0018897151,0.0003044193],"study_design_scores_gemma":[0.0020624346,0.000729837,0.25341055,0.00028172196,0.00043851385,0.00004048778,0.38775957,0.065848164,0.28238618,0.0043693776,0.0020131154,0.00066004426],"about_ca_topic_score_codex":0.02725651,"about_ca_topic_score_gemma":0.21007955,"teacher_disagreement_score":0.562497,"about_ca_system_score_codex":0.000034638397,"about_ca_system_score_gemma":0.00017565908,"threshold_uncertainty_score":0.97922105},"labels":[{"model":"gemma","categories":["sts"],"domain":null,"study_design":"qualitative","genre":"empirical","about_ca_system":false,"about_ca_topic":true,"confidence":"low"},{"model":"gpt","categories":["sts"],"domain":null,"study_design":"qualitative","genre":"empirical","about_ca_system":false,"about_ca_topic":true,"confidence":"high"}],"label_agreement":"agree"},{"id":"W4404104873","doi":"10.1183/13993003.congress-2024.oa4550","title":"How can gene editing of human pluripotent stem cells help understand the effect of genetics on respiratory diseases?","year":2024,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Induced pluripotent stem cell; Human Induced Pluripotent Stem Cells; Stem cell; Genome editing; Computational biology; Biology; Genetics; Gene; Computer science; CRISPR; Embryonic stem cell","score_opus":0.010186072692351236,"score_gpt":0.2674102541867096,"score_spread":0.2572241814943584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404104873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98968476,0.006128826,0.0033122578,0.00009884052,0.00028351523,0.00021377535,0.000058511338,0.000014147079,0.00020534312],"genre_scores_gemma":[0.99909365,0.00007264547,0.00003083281,0.00003620998,0.0003234696,0.0000071553663,0.0000117576565,0.000025233086,0.00039903546],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992243,0.00005276594,0.0001680031,0.0002296747,0.00016470031,0.00016057413],"domain_scores_gemma":[0.9995068,0.000036277168,0.000041886444,0.00032962277,0.000028750152,0.000056706893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014898948,0.00014560072,0.00014517653,0.000040546485,0.00004271601,0.000027190608,0.00014366067,0.00007228854,0.000004833363],"category_scores_gemma":[0.0000086266955,0.00009846469,0.00012599996,0.00007002372,0.00007153428,0.0000010327595,0.000068493224,0.00006947807,5.0245035e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015730486,0.000009887084,0.00029537998,0.00022926484,0.000079589845,0.0000036006704,0.000041518622,0.0016615855,0.99441266,0.0000648034,0.0008049324,0.0023810684],"study_design_scores_gemma":[0.00021973885,0.000892067,0.00032334455,0.000047615147,0.00006322893,0.0000013144863,0.00017320787,0.00022670528,0.9957464,0.000008056904,0.002196864,0.00010147967],"about_ca_topic_score_codex":0.00000577578,"about_ca_topic_score_gemma":0.000014246101,"teacher_disagreement_score":0.009408877,"about_ca_system_score_codex":0.000015062398,"about_ca_system_score_gemma":0.000027242462,"threshold_uncertainty_score":0.40152735},"labels":[],"label_agreement":null},{"id":"W4404107291","doi":"10.1016/j.xgen.2024.100693","title":"Seed sequences mediate off-target activity in the CRISPR-interference system","year":2024,"lang":"en","type":"article","venue":"Cell Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Roche (Canada)","funders":"Genentech","keywords":"CRISPR; Interference (communication); RNA interference; Computational biology; Biology; Chemistry; Cell biology; Computer science; Genetics; Telecommunications; RNA; Gene","score_opus":0.008048707273655628,"score_gpt":0.2594907858729802,"score_spread":0.25144207859932455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404107291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.972741,0.006770441,0.016884875,0.00010070867,0.0005296798,0.00015697148,0.000019260548,0.000023795252,0.0027732847],"genre_scores_gemma":[0.9986897,0.00043294154,0.0003498967,0.00004587618,0.00022206813,0.000018625273,0.000017518918,0.000016102102,0.00020727642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993287,0.000041038795,0.00012162901,0.0002532708,0.00006435847,0.00019102883],"domain_scores_gemma":[0.9996679,0.00002287699,0.000018367777,0.0002440306,0.0000131193365,0.000033698478],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024093637,0.0001198877,0.00009372593,0.000033343786,0.000029585352,0.000057248908,0.00024726946,0.000084890555,0.000004029196],"category_scores_gemma":[0.000008880121,0.000092656745,0.00005762934,0.00007805262,0.000028504875,0.0000026003581,0.00006130405,0.00012027683,0.000022784445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000145571385,0.00001361078,0.00034410827,0.00015798392,0.000015045074,0.000020429141,0.000511012,0.002389264,0.9948884,0.000048499907,0.0003383496,0.0012587073],"study_design_scores_gemma":[0.00017484062,0.00010988568,0.0014680615,0.000043659893,0.0000213186,0.00004114774,0.0010472477,0.014926146,0.9501451,0.000045545105,0.0317142,0.00026279603],"about_ca_topic_score_codex":0.000020596955,"about_ca_topic_score_gemma":0.000031839132,"teacher_disagreement_score":0.044743285,"about_ca_system_score_codex":0.000030780382,"about_ca_system_score_gemma":0.00006528515,"threshold_uncertainty_score":0.37784323},"labels":[],"label_agreement":null},{"id":"W4404109930","doi":"10.21203/rs.3.rs-5325410/v1","title":"Streamlined Protoplast Transfection System for In-vivo Validation and Transgene-free Genome Editing in Banana","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Optech (Canada)","funders":"","keywords":"Protoplast; Transgene; Genome editing; Transfection; In vivo; Genome; Biology; Computational biology; Cell biology; Gene; Biotechnology; Genetics","score_opus":0.02331804422986986,"score_gpt":0.36958679922345483,"score_spread":0.34626875499358495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404109930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846031,0.0026838854,0.008089297,0.0001611177,0.0002720046,0.0034679945,0.00040046114,0.000029427816,0.00029272254],"genre_scores_gemma":[0.99673814,0.00030014646,0.0003018408,0.0000013355505,0.0005862076,0.0016414964,0.00028508983,0.000048733997,0.000096999516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833727,0.00010939878,0.00030827645,0.0006186068,0.00023851453,0.00038793345],"domain_scores_gemma":[0.9994037,0.000038659135,0.000022119433,0.00034393786,0.00011799679,0.00007354476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010190343,0.00019239311,0.00021480842,0.00037198944,0.00004966834,0.0000804391,0.0001793024,0.00036395653,0.000003887981],"category_scores_gemma":[0.0001103249,0.00020491853,0.00008950919,0.0001881606,0.000031632677,0.000002556524,0.0002199359,0.00048400744,7.4664814e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002639481,0.000089488196,0.0018177092,0.02419505,0.00009168296,0.00002219715,0.0007861496,0.025190787,0.94205743,0.00014511171,0.00018189682,0.0051585394],"study_design_scores_gemma":[0.0023938294,0.00075832003,0.0033192204,0.0028257219,0.000032379423,0.000019901885,0.0018430206,0.012211405,0.97229415,0.0006523495,0.0030169985,0.00063272595],"about_ca_topic_score_codex":0.00014590866,"about_ca_topic_score_gemma":0.0010842561,"teacher_disagreement_score":0.03023669,"about_ca_system_score_codex":0.00011608392,"about_ca_system_score_gemma":0.00014027016,"threshold_uncertainty_score":0.8356335},"labels":[],"label_agreement":null},{"id":"W4404215117","doi":"10.1111/cpr.13771","title":"Predicting tumour resistance to paclitaxel and carboplatin utilising genome‐wide screening in haploid human embryonic stem cells","year":2024,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Azrieli Foundation; Israel Science Foundation","keywords":"Carboplatin; Paclitaxel; Embryonic stem cell; Ploidy; Biology; Genome; Stem cell; Computational biology; Cancer research; Genetics; Gene; Cancer; Chemotherapy; Cisplatin","score_opus":0.009343702285761214,"score_gpt":0.2615367105273459,"score_spread":0.2521930082415847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404215117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9713538,0.00476294,0.022893269,0.00008820951,0.00009424437,0.00029676282,0.0000066456632,0.00003349935,0.00047062148],"genre_scores_gemma":[0.99735135,0.000054057164,0.0010384226,0.000050649593,0.00019688439,0.000027850208,0.000029499552,0.000030533876,0.0012207775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907,0.00003347503,0.00021322857,0.0003757291,0.00009448317,0.00021309532],"domain_scores_gemma":[0.99971956,0.000014795297,0.000024241803,0.0001452758,0.000025565856,0.000070585884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002607737,0.00013528724,0.000104492115,0.00008938301,0.00008573444,0.00010340259,0.000061905,0.00008574062,0.000002232423],"category_scores_gemma":[0.0000145671365,0.00014986806,0.000028374692,0.00011742847,0.0000122009,0.000008627972,0.00005869659,0.0001189824,0.000002427335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014735278,0.000006843758,0.004476196,0.00013996437,0.000006687247,0.0000055710243,0.00051330845,0.004552285,0.98966396,0.00001156216,0.000084585634,0.00052430044],"study_design_scores_gemma":[0.00024192894,0.0000916974,0.0066477377,0.00014546503,0.000012682331,0.0000034589775,0.00030625486,0.007284665,0.9828001,0.000017480483,0.0022250665,0.00022344901],"about_ca_topic_score_codex":0.000008814197,"about_ca_topic_score_gemma":0.00018669917,"teacher_disagreement_score":0.025997518,"about_ca_system_score_codex":0.00001912956,"about_ca_system_score_gemma":0.000028367342,"threshold_uncertainty_score":0.61114424},"labels":[],"label_agreement":null},{"id":"W4404367132","doi":"10.1016/j.bbalip.2024.159577","title":"Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality","year":2024,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Liver injury; Lipid accumulation; Locus (genetics); Knockout mouse; Biology; Internal medicine; Endocrinology; Medicine; Gene; Genetics","score_opus":0.012250015399040779,"score_gpt":0.30649928120772774,"score_spread":0.29424926580868693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404367132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974364,0.0012324685,0.00018795647,0.00015385641,0.00009499719,0.00036671347,0.00020807143,0.000016755119,0.00030280484],"genre_scores_gemma":[0.99846,0.00039566078,0.0007182097,0.00007034045,0.00010132579,0.000022904313,0.00019665279,0.000023192397,0.00001169522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979869,0.00021098403,0.0006493206,0.0007136232,0.00011252161,0.00032662903],"domain_scores_gemma":[0.9992383,0.000051088464,0.0001474735,0.00036657287,0.00009031061,0.00010623863],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040078073,0.00031725725,0.00042295826,0.00015895642,0.000022606993,0.000019757852,0.00020714426,0.00036455377,0.0000021344265],"category_scores_gemma":[0.000185908,0.0003122168,0.00010922033,0.0003661355,0.0003054988,0.000012809282,0.00023762694,0.00022986105,9.281513e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028650768,0.00013908344,0.0011588192,0.00029231474,0.000057648038,0.000004683945,0.00010869722,0.000023110812,0.99665767,0.00019638521,0.000044244804,0.0010308638],"study_design_scores_gemma":[0.00085685076,0.0005551889,0.022834724,0.00018644215,0.000045059805,0.0000071374902,0.000044312743,0.0005532985,0.9743342,0.00016184854,0.000118724165,0.00030221717],"about_ca_topic_score_codex":0.0010924492,"about_ca_topic_score_gemma":0.00014901377,"teacher_disagreement_score":0.022323444,"about_ca_system_score_codex":0.000021125375,"about_ca_system_score_gemma":0.00013865509,"threshold_uncertainty_score":0.999933},"labels":[],"label_agreement":null},{"id":"W4404423815","doi":"10.1016/j.celrep.2024.114967","title":"Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase","year":2024,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Mitacs; National Institute of Allergy and Infectious Diseases; Cystic Fibrosis Canada; University of Manitoba; Foundation for the National Institutes of Health; Cystic Fibrosis Foundation; National Institutes of Health; National Science Foundation","keywords":"Hydrolase; Transfer RNA; Chemistry; Computational biology; Biology; Biochemistry; Enzyme; Gene; RNA","score_opus":0.005431683548207717,"score_gpt":0.26146691800513105,"score_spread":0.25603523445692333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404423815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99073535,0.00074431195,0.0059059504,0.000018074177,0.00093989394,0.00014185536,0.000010632935,0.000028553946,0.0014753494],"genre_scores_gemma":[0.9971671,0.000042819564,0.000928187,0.000021746811,0.00051932025,0.000010489512,0.00024926008,0.000030502177,0.0010305875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989941,0.000023282782,0.0003237504,0.00035302935,0.0001460118,0.00015979625],"domain_scores_gemma":[0.9994453,0.000010183528,0.00006717788,0.00033066177,0.000049287144,0.00009739809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018701323,0.00014170365,0.0001317292,0.000048602287,0.00002391763,0.00003839419,0.00006577745,0.00011766184,0.00009981907],"category_scores_gemma":[0.000041959753,0.00014152464,0.00010202211,0.00005629472,0.000029308369,0.0000063147436,0.00004398063,0.000058927177,0.0000049628675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037572812,0.00003996926,0.0001259632,0.00006257319,0.00002764038,0.0001328147,0.0000691959,0.0011886222,0.995531,0.0000067632545,0.002043057,0.00073481473],"study_design_scores_gemma":[0.0001570868,0.00020443402,0.00022273939,0.000021529786,0.00003837732,0.00008063278,0.00002619458,0.00019432826,0.9740262,0.000038935355,0.02482914,0.00016039467],"about_ca_topic_score_codex":0.000009896801,"about_ca_topic_score_gemma":0.000010194638,"teacher_disagreement_score":0.022786083,"about_ca_system_score_codex":0.000013323858,"about_ca_system_score_gemma":0.00015266775,"threshold_uncertainty_score":0.5771207},"labels":[],"label_agreement":null},{"id":"W4404427765","doi":"10.5376/gab.2024.15.0013","title":"Advancements in Gene Editing Technologies for Mosquito Research","year":2024,"lang":"en","type":"article","venue":"Genomics and Applied Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genome editing; Biology; Computational biology; Computer science; Gene; Genetics; CRISPR","score_opus":0.019793859326030137,"score_gpt":0.379463701319589,"score_spread":0.3596698419935589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404427765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705898,0.0094795935,0.018477462,0.0002647493,0.00025408244,0.0003925537,0.000042149044,0.000034234537,0.00046538733],"genre_scores_gemma":[0.9930725,0.0014355277,0.004864155,0.000025254476,0.00028069422,0.00016269762,0.00008825724,0.000016513779,0.00005439868],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991791,0.0000069405055,0.000130728,0.00036046543,0.00002546132,0.00029725832],"domain_scores_gemma":[0.99979514,0.000024481331,0.000010020276,0.00013328384,0.000016870523,0.000020220214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031219012,0.000090010166,0.00009712685,0.000095855445,0.000055900833,0.000022170449,0.00010776045,0.00015369456,0.0000011200608],"category_scores_gemma":[0.000024005709,0.0000850409,0.000020987034,0.00008353546,0.000079277015,8.9967733e-7,0.00017095587,0.00010166469,0.0000021007543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018650137,0.000006512542,0.00009462041,0.000034135526,0.000013625733,6.0485195e-7,0.00002975786,0.0001387762,0.9343088,0.0035609028,0.00019445145,0.061599128],"study_design_scores_gemma":[0.00034905455,0.00016881044,0.00010266742,0.000010635097,0.0000043785562,0.0000063947505,0.00042310767,0.00068851275,0.7673406,0.0065314695,0.22421499,0.00015937659],"about_ca_topic_score_codex":0.00000299658,"about_ca_topic_score_gemma":0.000012177931,"teacher_disagreement_score":0.22402054,"about_ca_system_score_codex":0.000015547908,"about_ca_system_score_gemma":0.000019776558,"threshold_uncertainty_score":0.34678674},"labels":[],"label_agreement":null},{"id":"W4404428029","doi":"10.5376/gab.2024.15.0012","title":"CRISPR-Cas9 Mediated Gene Editing in Tilapia: Enhancing Growth Rates and Disease Resistance","year":2024,"lang":"en","type":"article","venue":"Genomics and Applied Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Biology; Gene; Genetics; Disease; Medicine; Internal medicine","score_opus":0.004067579905827407,"score_gpt":0.26148917244004194,"score_spread":0.25742159253421454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404428029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9726602,0.020497397,0.005708615,0.00045765148,0.00017808659,0.0001472993,0.00005248534,0.000020110694,0.00027815453],"genre_scores_gemma":[0.99555683,0.002727496,0.00086981524,0.00015929097,0.0004295114,0.000027949358,0.00013840137,0.00002175964,0.000068960384],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991049,0.000013627554,0.00018558768,0.00042333867,0.000025623398,0.00024693343],"domain_scores_gemma":[0.9997067,0.00003080843,0.000021876667,0.0001098511,0.000012923729,0.00011786779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016285713,0.00014993643,0.00014508882,0.000059940736,0.000048090773,0.000033744338,0.00006348462,0.00011839234,0.0000035102773],"category_scores_gemma":[0.000041578518,0.00014343053,0.000022446695,0.000068264795,0.000071316485,0.0000018493902,0.00010957735,0.00009668489,0.0000025929987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004001034,0.000005195263,0.0006097287,0.00008380446,0.000021110052,0.000007363437,0.0000828437,0.000023736344,0.9961061,0.0016436559,0.00017083596,0.0012055994],"study_design_scores_gemma":[0.0010866628,0.00009943772,0.007478722,0.00007584102,0.000058446713,0.000023918938,0.00034219638,0.0013959968,0.9169431,0.006109531,0.0655737,0.00081248826],"about_ca_topic_score_codex":0.0000055017986,"about_ca_topic_score_gemma":0.00009201569,"teacher_disagreement_score":0.07916305,"about_ca_system_score_codex":0.000010843463,"about_ca_system_score_gemma":0.000042051164,"threshold_uncertainty_score":0.58489275},"labels":[],"label_agreement":null},{"id":"W4404509302","doi":"10.54254/2753-8818/58/20241351","title":"Current trends and ethical considerations in gene therapy","year":2024,"lang":"en","type":"article","venue":"Theoretical and Natural Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Current (fluid); Engineering ethics; Genetic enhancement; Psychology; Computational biology; Gene; Biology; Genetics; Engineering","score_opus":0.006673560900842339,"score_gpt":0.3357007997233134,"score_spread":0.3290272388224711,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404509302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9725201,0.024643289,0.0004166191,0.001957391,0.00016333823,0.00003175983,0.000002336528,0.000009299505,0.00025586996],"genre_scores_gemma":[0.9981619,0.0013734294,0.00024928982,0.00013916119,0.000056210163,0.000002588227,0.0000021145484,0.0000026525097,0.000012632671],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949694,0.000013595537,0.00006478164,0.00021596973,0.00007691799,0.00013180927],"domain_scores_gemma":[0.9998353,0.000028207054,0.0000028852699,0.000058701164,0.000012984866,0.000061918116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024023296,0.000057849273,0.000047472473,0.000051691044,0.00005125958,0.00005569233,0.000041386127,0.000049384435,0.000018713816],"category_scores_gemma":[0.00006197623,0.00004008476,0.000012578785,0.00014504166,0.000765865,0.000002398095,0.00005488647,0.00017015147,6.5354914e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009710077,0.0000065233194,0.00017998213,0.000006148592,0.000002196531,0.000003427913,0.00009046665,0.0000056767585,0.56186295,0.3524973,0.000049203045,0.08528641],"study_design_scores_gemma":[0.000764509,0.0004004285,0.069913454,0.00008634162,0.000012778659,0.0002703007,0.000038217593,0.01990919,0.8042439,0.09524685,0.008547635,0.0005663655],"about_ca_topic_score_codex":0.0000014682298,"about_ca_topic_score_gemma":0.000002278221,"teacher_disagreement_score":0.25725046,"about_ca_system_score_codex":0.0000032060216,"about_ca_system_score_gemma":0.000030312314,"threshold_uncertainty_score":0.28218615},"labels":[],"label_agreement":null},{"id":"W4404520265","doi":"10.1101/2024.11.18.24317509","title":"Implementing a consultation service for translating genomic research findings into the clinic: lessons from the SickKids Genome Board","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Service (business); Editorial board; Genome; Business; Library science; Genetics; Computer science; Biology; Marketing; Gene","score_opus":0.06123233675458654,"score_gpt":0.4242295247058759,"score_spread":0.3629971879512893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404520265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9755963,0.006478521,0.0067630387,0.0091983555,0.00043826044,0.0010429885,0.00024159551,0.00002745313,0.00021346967],"genre_scores_gemma":[0.9948264,0.00035667658,0.002144661,0.00028069728,0.0010636601,0.00041783103,0.0005719931,0.00007697131,0.00026110906],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979701,0.00015728586,0.00045045424,0.0006846466,0.00022483141,0.000512675],"domain_scores_gemma":[0.99855316,0.00043853436,0.00007873433,0.0006649462,0.00020923854,0.000055380224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026181731,0.00024868458,0.00020738924,0.000049192273,0.00043337862,0.00019118849,0.00073729816,0.00025751156,0.000025883968],"category_scores_gemma":[0.0002815667,0.0001749109,0.00020147253,0.00015223637,0.000081164064,0.0000014544131,0.001201604,0.00076470163,0.000025893658],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055599594,0.000013471216,0.0009978948,0.0003433234,0.00035285138,0.0000015955096,0.014010301,0.0011664769,0.9761375,0.00009128184,0.0006623751,0.0061672977],"study_design_scores_gemma":[0.0029841044,0.00043236822,0.036020447,0.0008665675,0.0011779246,0.000011035605,0.02184452,0.024013143,0.26054397,0.024322331,0.6255535,0.0022301],"about_ca_topic_score_codex":0.00060541235,"about_ca_topic_score_gemma":0.00224255,"teacher_disagreement_score":0.7155936,"about_ca_system_score_codex":0.00003434511,"about_ca_system_score_gemma":0.00021047716,"threshold_uncertainty_score":0.713266},"labels":[],"label_agreement":null},{"id":"W4404636723","doi":"10.1002/ejhf.3516","title":"State of the Art and Perspectives of Gene Therapy in Heart Failure. A Scientific Statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial &amp; Pericardial Diseases","year":2024,"lang":"en","type":"review","venue":"European Journal of Heart Failure","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Surgical Specialties (Canada)","funders":"H2020 European Research Council; Instituto de Salud Carlos III; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; National Institutes of Health; Deutsche Krebshilfe; Norges Forskningsråd; Ministero della Salute; Innovative Medicines Initiative; Hartstichting; Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares; National Institute for Health and Care Research; Bundesministerium für Bildung und Forschung; King's College London; Fondation Leducq; Deutsches Zentrum für Herz-Kreislaufforschung; European Commission; British Heart Foundation; Dutch Cardiovascular Alliance; Deutsche Forschungsgemeinschaft; UK Research and Innovation; Foundation for Cardiovascular Research","keywords":"Heart failure; Medicine; Genetic enhancement; Disease; Modalities; CRISPR; Gene delivery; Genome editing; Bioinformatics; Heart disease; Intensive care medicine; Gene; Cardiology; Internal medicine; Genetics; Biology","score_opus":0.01962384967265613,"score_gpt":0.25667675883705215,"score_spread":0.23705290916439603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404636723","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15245682,0.8416444,0.000060223734,0.0037149098,0.00068067113,0.0012148395,0.00019893155,0.0000037908871,0.000025375602],"genre_scores_gemma":[0.620682,0.37782976,0.0004610939,0.00011693318,0.00063906034,0.000017336308,0.000012527858,0.00011387131,0.00012741958],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954543,0.001977293,0.00090542395,0.000383598,0.0010163169,0.000263075],"domain_scores_gemma":[0.99795735,0.0001506628,0.00067340705,0.0008607735,0.00029860524,0.000059204012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004044024,0.0003717002,0.0010785583,0.00008341285,0.0001906744,0.0000985807,0.00051917054,0.00008798319,0.0000027548904],"category_scores_gemma":[0.0002678455,0.00016557453,0.0016221583,0.0003594747,0.00052119733,0.000009228322,0.00027374885,0.0006518512,9.452496e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044605574,0.002325735,0.016278664,0.015053591,0.05069271,0.00004443727,0.054906145,0.07806119,0.23676164,0.00044111355,0.38904384,0.15193038],"study_design_scores_gemma":[0.0009213268,0.00022726247,0.0026376664,0.0017508953,0.0007710727,0.000048281887,0.0006121635,0.000007222881,0.0010962562,0.0000118759945,0.9917349,0.0001810347],"about_ca_topic_score_codex":0.000010494049,"about_ca_topic_score_gemma":0.000049476195,"teacher_disagreement_score":0.6026911,"about_ca_system_score_codex":0.00014100659,"about_ca_system_score_gemma":0.00044186076,"threshold_uncertainty_score":0.67519337},"labels":[],"label_agreement":null},{"id":"W4404660300","doi":"10.1111/gtc.13184","title":"Generation of Monosomy 21q Human <scp>iPS</scp> Cells by <scp>CRISPR</scp> /Cas9‐Mediated Interstitial Megabase Deletion","year":2024,"lang":"en","type":"article","venue":"Genes to Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences; Institute of Genetics; Japan Agency for Medical Research and Development; Support for Pioneering Research Initiated by the Next Generation","keywords":"Biology; Monosomy; Genetics; Chromosome 21; Transcriptome; Cas9; CRISPR; Gene; Induced pluripotent stem cell; Ploidy; X-inactivation; Chromosome; Molecular biology; Cell biology; Embryonic stem cell; Gene expression; X chromosome; Karyotype","score_opus":0.01322786187091963,"score_gpt":0.28291148267688426,"score_spread":0.26968362080596464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404660300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9316188,0.0057534003,0.060112897,0.000029263652,0.0011833222,0.00037617856,0.00022539294,0.00006389927,0.0006368139],"genre_scores_gemma":[0.99265856,0.0006143545,0.0013191121,0.00016182532,0.0009797598,0.00005378863,0.00094036275,0.000080895705,0.0031913517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981861,0.00006183954,0.00044588395,0.0006295481,0.0002325929,0.00044400097],"domain_scores_gemma":[0.9991315,0.000056124805,0.00007299218,0.00040799755,0.00011394575,0.00021742808],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001951871,0.0003301312,0.00025557893,0.00015124226,0.000082769526,0.00008706646,0.00025298138,0.00026649504,0.00002135201],"category_scores_gemma":[0.000060261245,0.00035247393,0.00017461968,0.00022163852,0.0000531801,0.000011398362,0.00014959913,0.00013974553,0.00010490035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000025954732,0.000048903246,0.000029740184,0.00010295969,0.000070989765,0.000009023378,0.00026139643,0.0039271316,0.89617103,0.000011277657,0.09811417,0.00125079],"study_design_scores_gemma":[0.00023525255,0.0003165235,0.000024880394,0.000029143677,0.000049815935,0.000005716505,0.00014739129,0.0019609134,0.80760074,0.0000052281243,0.1895441,0.00008031257],"about_ca_topic_score_codex":0.000058304522,"about_ca_topic_score_gemma":0.00004345419,"teacher_disagreement_score":0.09142993,"about_ca_system_score_codex":0.000035414778,"about_ca_system_score_gemma":0.00006114421,"threshold_uncertainty_score":0.9998927},"labels":[],"label_agreement":null},{"id":"W4404685525","doi":"10.20944/preprints202411.1633.v1","title":"The Advancement and Applications of Prime Editing","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; China Scholarship Council","keywords":"CRISPR; Genome editing; Computer science; Transcription activator-like effector nuclease; Computational biology; Cas9; Double strand; Transversion; Biology; Prime (order theory); Genetics; Gene; Mutation; DNA repair; Mathematics","score_opus":0.02677954820073139,"score_gpt":0.3597308381265885,"score_spread":0.3329512899258571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404685525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9468247,0.019146107,0.025621073,0.00064877945,0.0007791003,0.0011418775,0.00005505567,0.00005158605,0.005731664],"genre_scores_gemma":[0.9952216,0.0025362184,0.00025737876,0.000013532893,0.00046492077,0.00027734568,0.00003779158,0.0000229817,0.0011682301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990822,0.000016653476,0.00024024182,0.00041899385,0.00009889353,0.0001430189],"domain_scores_gemma":[0.99914986,0.000014788386,0.00008508493,0.0006485351,0.00005833459,0.000043401273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025387472,0.00014266006,0.00011965208,0.000024383775,0.00005564576,0.000011493552,0.0002286254,0.0001248837,0.000010204861],"category_scores_gemma":[0.00005190648,0.000121916964,0.00007297471,0.000035983507,0.00007208967,5.455773e-7,0.0019633505,0.0002178029,0.000019985908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024923922,0.00005584544,0.022252513,0.00081206555,0.00036279668,0.0000011729289,0.00026142737,0.0026333935,0.93000734,0.0016541694,0.00011314746,0.04182121],"study_design_scores_gemma":[0.00009731046,0.000017318427,0.008900202,0.00009138027,0.000057483154,0.0000044973035,0.00011127657,0.00015486205,0.818823,0.0013561123,0.17019959,0.00018699611],"about_ca_topic_score_codex":0.00001124951,"about_ca_topic_score_gemma":0.000008012293,"teacher_disagreement_score":0.17008644,"about_ca_system_score_codex":0.000010647471,"about_ca_system_score_gemma":0.000048371192,"threshold_uncertainty_score":0.49716297},"labels":[],"label_agreement":null},{"id":"W4404704552","doi":"10.21203/rs.3.rs-4619764/v1","title":"Molecular engineering and dynamic activation mechanism of a PAM-flexible compact CRISPR-Cas9","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cas9; CRISPR; Nuclease; DNA; Biology; Gene; Computational biology; Genetics","score_opus":0.019675581632187578,"score_gpt":0.3899424369165639,"score_spread":0.3702668552843763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404704552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500623,0.006986141,0.041291416,0.00023754683,0.0001852776,0.0006563938,0.0000980053,0.0000508017,0.00043212442],"genre_scores_gemma":[0.99811816,0.0007201352,0.00061596616,0.0000066566263,0.00008980816,0.000046330708,0.0001802245,0.000070567985,0.0001521286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836814,0.00006501148,0.00023678866,0.0005425614,0.0004055905,0.00038191976],"domain_scores_gemma":[0.9990749,0.000034003166,0.00003996543,0.00052557344,0.00020094682,0.00012464098],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048608976,0.00024417453,0.00025358883,0.0003160546,0.000038737868,0.00006934401,0.00022140547,0.0003579516,0.000010992062],"category_scores_gemma":[0.0001610374,0.00025524426,0.00012856527,0.00018197883,0.000049458085,0.0000020397017,0.00094010803,0.00072595873,0.00000424709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028297447,0.000028681054,0.000022869304,0.0024629822,0.00013274407,0.000011233628,0.000102009915,0.01771172,0.9773913,0.0011285621,0.00017533051,0.0008042417],"study_design_scores_gemma":[0.00019334264,0.00023238806,0.00045654917,0.000797384,0.000025330295,0.000009756655,0.00012339295,0.036646508,0.95819163,0.00208271,0.0009543417,0.00028667503],"about_ca_topic_score_codex":0.00007769592,"about_ca_topic_score_gemma":0.0000060433363,"teacher_disagreement_score":0.048055887,"about_ca_system_score_codex":0.00005265325,"about_ca_system_score_gemma":0.00014581147,"threshold_uncertainty_score":0.99999},"labels":[],"label_agreement":null},{"id":"W4404727663","doi":"10.1016/j.omtn.2024.102401","title":"Precise template-free correction restores gene function in Tay-Sachs disease while reframing is ineffective","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Sickkids Research Institute; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Frameshift mutation; Cognitive reframing; Gene; Genetics; Function (biology); Mutation; Biology; Psychology","score_opus":0.006467463506991458,"score_gpt":0.2634768283711169,"score_spread":0.25700936486412546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404727663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9258121,0.014324811,0.057802957,0.00014574939,0.0010875403,0.00038036966,0.00002487531,0.00009058389,0.0003309596],"genre_scores_gemma":[0.99761325,0.0007504104,0.00037998584,0.0002396077,0.00024335191,0.00009654833,0.000113372575,0.000087288405,0.00047620203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985889,0.00008029721,0.00022955541,0.0006005662,0.00019973611,0.00030091126],"domain_scores_gemma":[0.99917835,0.0000163151,0.00003236499,0.00060606323,0.00004784752,0.00011905611],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019489447,0.00026768417,0.00016628293,0.00015849438,0.00006944453,0.000076972916,0.00020775328,0.00018813131,0.000057617857],"category_scores_gemma":[0.00005707903,0.00026924524,0.00015151738,0.00028737128,0.000044114513,0.000012846755,0.00009691283,0.00020739502,0.000022431781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005635466,0.000068927475,0.001598648,0.000040781364,0.00012383545,0.00006560189,0.00024553193,0.0022054715,0.9614172,0.000021504575,0.0030383002,0.03061064],"study_design_scores_gemma":[0.0012753838,0.00080184994,0.017361829,0.00014008342,0.000056173652,0.00002638748,0.00006892228,0.006044223,0.89431113,0.0004314059,0.07889795,0.00058463874],"about_ca_topic_score_codex":0.000046578505,"about_ca_topic_score_gemma":0.000017510856,"teacher_disagreement_score":0.07585965,"about_ca_system_score_codex":0.00006117203,"about_ca_system_score_gemma":0.000055218024,"threshold_uncertainty_score":0.999976},"labels":[],"label_agreement":null},{"id":"W4404865467","doi":"10.1039/d4md00735b","title":"Toward target 2035: EUbOPEN - a public–private partnership to enable &amp; unlock biology in the open","year":2024,"lang":"en","type":"editorial","venue":"RSC Medicinal Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Princess Margaret Cancer Centre; Montreal Neurological Institute and Hospital; Structural Genomics Consortium; University of Toronto","funders":"European Commission; European Federation of Pharmaceutical Industries and Associations; Diamond Light Source; Innovative Medicines Initiative; McGill University","keywords":"General partnership; Open data; Public–private partnership; Biology; Business; Political science; Computer science; World Wide Web; Law","score_opus":0.03290511780366147,"score_gpt":0.36479351641657504,"score_spread":0.3318883986129136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404865467","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015724154,0.036872726,0.0065137763,0.015597537,0.7232637,0.0048846547,0.0014750785,0.00023704345,0.19543135],"genre_scores_gemma":[0.10896173,0.0010603053,0.0012417694,0.0011824289,0.85435057,0.000840551,0.009276266,0.00023332315,0.022853075],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99704146,0.00009532014,0.00053360284,0.0010698506,0.00047963922,0.0007801334],"domain_scores_gemma":[0.9982887,0.0001362072,0.00010620285,0.001054848,0.00012626615,0.0002878144],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013457289,0.00054221554,0.0005846399,0.000071081995,0.00006787399,0.0002254048,0.0025298584,0.001165818,0.00026376417],"category_scores_gemma":[0.0016134023,0.0004177489,0.0001512134,0.00033883084,0.000109336564,0.000005628978,0.0012004691,0.0011468305,0.00008475807],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000080773396,0.000042175387,0.000032562304,0.00046724317,0.00009450172,0.00004370148,0.0002216342,0.00003349805,0.059081774,0.000020240383,0.9396365,0.00024539168],"study_design_scores_gemma":[0.00052008487,0.0001257722,0.0000030480098,0.00021021858,0.00005530665,0.00002811379,0.00019011824,0.000007759377,0.03453737,0.0003213619,0.96352345,0.0004774215],"about_ca_topic_score_codex":0.00015392831,"about_ca_topic_score_gemma":0.00007431992,"teacher_disagreement_score":0.17257828,"about_ca_system_score_codex":0.00008390291,"about_ca_system_score_gemma":0.0006604696,"threshold_uncertainty_score":0.99982744},"labels":[],"label_agreement":null},{"id":"W4404868962","doi":"10.5376/bm.2024.15.0022","title":"CRISPR-based Gene Editing in &lt;i&gt;Bt&lt;/i&gt; for Improved Insecticidal Properties","year":2024,"lang":"en","type":"article","venue":"Bioscience Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Gene; Biology; Genetics; Biotechnology; Computational biology","score_opus":0.027128343760702393,"score_gpt":0.365624510192174,"score_spread":0.3384961664314716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404868962","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20366478,0.00519472,0.7887458,0.0003404385,0.0014478633,0.0003759975,0.000019992563,0.000054935077,0.00015545991],"genre_scores_gemma":[0.7440646,0.000051611165,0.2546999,0.00017365563,0.0005018504,0.00012868115,0.000013009794,0.00003199953,0.00033466253],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984511,0.00009896042,0.00027645988,0.0005997986,0.00011681152,0.00045686433],"domain_scores_gemma":[0.9994464,0.000064869484,0.000035072288,0.00029161142,0.000068894245,0.00009317837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014230654,0.00020151227,0.00017623327,0.00014979373,0.000099816236,0.000102221304,0.00027883885,0.0001479396,0.000006147009],"category_scores_gemma":[0.0007234752,0.00017462109,0.00011696961,0.00032715214,0.000112731774,0.000009748048,0.00009861357,0.000093676594,0.0000018133948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020183401,0.000022969045,0.000026578862,0.000086016,0.000007482197,0.000001633356,0.000067754205,0.0005734881,0.9765051,0.00008222755,0.00018256641,0.022424022],"study_design_scores_gemma":[0.0002317866,0.00021157238,0.00038128972,0.000039503768,0.0000125425895,0.000007051533,0.000025506068,0.05669258,0.88101697,0.00004289184,0.06111794,0.00022036336],"about_ca_topic_score_codex":0.000008449488,"about_ca_topic_score_gemma":0.00003736784,"teacher_disagreement_score":0.54039985,"about_ca_system_score_codex":0.000035161094,"about_ca_system_score_gemma":0.00019349103,"threshold_uncertainty_score":0.7120842},"labels":[],"label_agreement":null},{"id":"W4404926332","doi":"10.1007/978-1-0716-4160-6_7","title":"Rapid Generation of Recombinant Poxviruses Using CRISPR/Cas9 Gene Editing","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Genome editing; Recombinant DNA; Biology; Cas9; Virology; Computational biology; Subgenomic mRNA; Gene; Genetics","score_opus":0.04961032831552845,"score_gpt":0.455908375968573,"score_spread":0.4062980476530445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404926332","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20825392,0.013250774,0.7769043,0.000038204325,0.001320441,0.000115553055,0.0000064077335,0.000014675124,0.000095741125],"genre_scores_gemma":[0.24358185,0.00052473595,0.7552472,0.00009664171,0.0003810344,0.000018834622,0.00007080407,0.000043097672,0.00003585163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998438,0.00039446287,0.00038409224,0.0004454565,0.000057649326,0.00028036037],"domain_scores_gemma":[0.9995156,0.000037141966,0.000054621723,0.0003016639,0.000048390764,0.000042601998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009080906,0.0001814189,0.00024092845,0.0001780884,0.000027907872,0.000015896218,0.00015069469,0.00024441554,0.000019616089],"category_scores_gemma":[0.0002610529,0.00017944444,0.00012409483,0.00021610697,0.00007146794,0.00000297244,0.00011979889,0.00013652096,0.0000012277986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007692362,0.000018454022,0.0002479996,0.000043009448,0.000046988003,0.000014065295,0.000037884492,0.0017641805,0.96831065,0.0003606937,0.000056479792,0.029091923],"study_design_scores_gemma":[0.0001730263,0.00015435432,0.000034346194,0.000029378063,0.000025138754,0.000045171048,0.000024241761,0.017356679,0.9727017,0.00038139138,0.008896279,0.00017825824],"about_ca_topic_score_codex":0.00003320187,"about_ca_topic_score_gemma":0.000006923748,"teacher_disagreement_score":0.03532792,"about_ca_system_score_codex":0.000020496129,"about_ca_system_score_gemma":0.000057359684,"threshold_uncertainty_score":0.7317532},"labels":[],"label_agreement":null},{"id":"W4404940657","doi":"10.1038/s41571-024-00966-z","title":"Synthetic lethal strategies for the development of cancer therapeutics","year":2024,"lang":"en","type":"review","venue":"Nature Reviews Clinical Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Telesta Therapeutics (Canada)","funders":"","keywords":"Synthetic lethality; CRISPR; Medicine; Computational biology; Epigenetics; Drug discovery; Bioinformatics; DNA repair; Biology; Genetics; DNA; Gene","score_opus":0.15958765689535367,"score_gpt":0.5725352650957538,"score_spread":0.4129476082004001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404940657","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000003209929,0.9928209,0.0031163536,0.000119828415,0.0021334894,0.001514783,0.000042483054,0.000008781993,0.00024013747],"genre_scores_gemma":[0.000032920027,0.9936628,0.0037649756,0.00019197754,0.0011474632,0.00075220765,0.00006984577,0.000059684637,0.00031813956],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970336,0.00026820725,0.0017808947,0.0005448999,0.00010808176,0.00026429238],"domain_scores_gemma":[0.99812925,0.000647129,0.0005263576,0.0005466334,0.0000902684,0.000060375387],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0019691868,0.0004023265,0.0020542399,0.000040998435,0.000049645834,0.00001620349,0.00057016924,0.0018683689,0.000013584824],"category_scores_gemma":[0.00029564538,0.00021034447,0.0013128782,0.00013524268,0.00014790692,0.0000011556382,0.00017040287,0.001139734,0.000014045434],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010071219,0.00004633551,4.9148724e-7,0.010536035,0.0007075755,7.814794e-7,0.00001842613,0.0000021548644,0.00001765606,0.00012698282,0.0023287262,0.98620474],"study_design_scores_gemma":[0.00011773163,0.00021561934,0.0000015690164,0.0031902115,0.0029544532,0.000009766292,0.0000150900905,0.000006112459,0.000024739524,0.000027997246,0.9932065,0.00023022252],"about_ca_topic_score_codex":9.044335e-7,"about_ca_topic_score_gemma":0.0000886082,"teacher_disagreement_score":0.99087775,"about_ca_system_score_codex":0.000042552216,"about_ca_system_score_gemma":0.0018936375,"threshold_uncertainty_score":0.99942744},"labels":[],"label_agreement":null},{"id":"W4405007703","doi":"10.1101/2024.12.04.626608","title":"BEVA2.0: Modular Assembly of Golden Gate-Compatible Vectors with Expanded Utility for Genetic Engineering","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Golden gate; Modular design; Computer science; Engineering; Programming language; Structural engineering","score_opus":0.008642005971342836,"score_gpt":0.24003976942897182,"score_spread":0.23139776345762897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405007703","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94536144,0.0041612093,0.048515607,0.000023370161,0.00067205506,0.00087483815,0.00025735225,0.00013076676,0.0000033488698],"genre_scores_gemma":[0.9784908,0.00015393912,0.020386228,0.000014622356,0.00043341852,0.00030831646,0.0000034356055,0.00020166884,0.0000075695552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975865,0.00003224074,0.00052603194,0.0010433405,0.0002713859,0.0005405362],"domain_scores_gemma":[0.9980356,0.000026732823,0.00018505807,0.0012035655,0.00034268908,0.0002063466],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025708406,0.00058611576,0.000590468,0.00019086213,0.000049761933,0.000084730396,0.00045863978,0.00050819834,0.000006990338],"category_scores_gemma":[0.00010229549,0.00061987014,0.00024849534,0.0002474839,0.00006409395,0.000004753532,0.00044539906,0.00037271023,0.000004654841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004892703,0.00006210439,0.0020390963,0.0017109042,0.00038155852,0.000009492505,0.000008375273,0.018211802,0.9773946,0.000028024491,0.00010075678,0.0000043955115],"study_design_scores_gemma":[0.00049814774,0.00022344508,0.03893325,0.00040315415,0.00023505172,7.0584555e-8,0.0000033822002,0.013914264,0.9436562,0.0000016597905,0.0014163317,0.0007150639],"about_ca_topic_score_codex":0.000033682212,"about_ca_topic_score_gemma":0.0000065437634,"teacher_disagreement_score":0.036894154,"about_ca_system_score_codex":0.0000589804,"about_ca_system_score_gemma":0.00036550622,"threshold_uncertainty_score":0.99962527},"labels":[],"label_agreement":null},{"id":"W4405095423","doi":"10.1101/2024.12.04.24318434","title":"Integrating Whole Genome and Transcriptome Sequencing to Characterize the Genetic Architecture of Isoform Variation and its Implications for Health and Disease","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Genome; Transcriptome; Computational biology; Biology; Genetics; Genetic architecture; Variation (astronomy); Disease; Genetic variation; Whole genome sequencing; Gene; Medicine; Gene expression; Phenotype","score_opus":0.015685353750148193,"score_gpt":0.29929305446441806,"score_spread":0.2836077007142699,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405095423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.931984,0.01219944,0.049879413,0.004627804,0.00007454797,0.0006823291,0.0005396567,0.00000910467,0.0000036730685],"genre_scores_gemma":[0.9961552,0.0006737852,0.0023742025,0.00029201343,0.00013014697,0.00016631829,0.00015116339,0.000024572813,0.000032599986],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99923277,0.000020424586,0.00021184118,0.00034748833,0.000043079304,0.00014441345],"domain_scores_gemma":[0.9994989,0.000016664406,0.000058627687,0.00020708027,0.000047554426,0.00017115547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016499907,0.00015252233,0.0001580456,0.000051458956,0.00006741928,0.00003922177,0.00008932538,0.00007406193,4.323612e-7],"category_scores_gemma":[0.00009727716,0.000119693315,0.000038418824,0.000049045288,0.000023783883,0.0000011239807,0.00018869531,0.0001309469,1.025013e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019516872,0.0000054562033,0.00046289738,0.0009118128,0.000041883362,1.6014147e-7,0.0022948189,0.00039000434,0.991315,0.00009052048,0.00000873559,0.004459205],"study_design_scores_gemma":[0.000707819,0.0008739604,0.9518906,0.0008249532,0.00033222273,0.00005807476,0.0004200505,0.008474699,0.018332632,0.00677884,0.010325676,0.0009804867],"about_ca_topic_score_codex":0.000011238271,"about_ca_topic_score_gemma":0.000018300927,"teacher_disagreement_score":0.97298235,"about_ca_system_score_codex":0.000012014791,"about_ca_system_score_gemma":0.00013779268,"threshold_uncertainty_score":0.4880952},"labels":[],"label_agreement":null},{"id":"W4405135055","doi":"10.1101/2024.12.03.626739","title":"Fusions of catalytically inactive RusA to FokI nuclease coupled with PNA enable programable site-specific double-stranded DNA breaks","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kootenay Association for Science & Technology","funders":"","keywords":"Nuclease; FokI; DNA; Double stranded; Molecular biology; Biology; Chemistry; Genetics; Gene; Allele","score_opus":0.00812116121220246,"score_gpt":0.23962503878184122,"score_spread":0.23150387756963875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405135055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992108,0.0015082279,0.0039183614,0.00012375622,0.00040576558,0.001347163,0.00033902406,0.00014872993,0.00010097935],"genre_scores_gemma":[0.99349505,0.00022545332,0.005375116,0.00005682978,0.00033907537,0.00027567748,0.000006583964,0.00018462398,0.000041620857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972513,0.000030581155,0.00049977115,0.0012066168,0.00037537626,0.0006363786],"domain_scores_gemma":[0.9975013,0.000018173234,0.0001609436,0.0013641468,0.000518011,0.0004374123],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003006367,0.0006167096,0.00058587646,0.00020917015,0.0001344892,0.00015603626,0.00050084566,0.00052536384,0.000036152975],"category_scores_gemma":[0.000041013074,0.0006012508,0.00019603613,0.00046745356,0.00012927389,0.000005979867,0.0013871216,0.00055078795,0.000040880255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004883812,0.00019551312,0.0002449035,0.00054424215,0.00027894537,0.000050990326,0.00003192086,0.0016406461,0.9958556,0.00019308129,0.00047031944,0.0000054461716],"study_design_scores_gemma":[0.0012132993,0.00038421052,0.0019440266,0.0004972036,0.0002352748,1.7694282e-7,0.000012505155,0.00043997983,0.98460585,0.0000036076099,0.0097895535,0.00087433634],"about_ca_topic_score_codex":0.00013754399,"about_ca_topic_score_gemma":0.000038622133,"teacher_disagreement_score":0.011249784,"about_ca_system_score_codex":0.00010285693,"about_ca_system_score_gemma":0.00051030965,"threshold_uncertainty_score":0.99964386},"labels":[],"label_agreement":null},{"id":"W4405156650","doi":"10.1101/2024.12.08.627374","title":"Degron-modified Cas12a enhances single-cell CRISPR screening","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"CRISPR; Degron; Computational biology; Biology; Genetics; Gene","score_opus":0.013681483378568404,"score_gpt":0.2531450093007321,"score_spread":0.2394635259221637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405156650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9321789,0.017469712,0.04673559,0.000117114905,0.0022501335,0.00056167855,0.0002081579,0.00031483022,0.00016384896],"genre_scores_gemma":[0.9884146,0.00052863825,0.0092819305,0.00013004981,0.0011743535,0.00014570169,0.00000292117,0.00024712164,0.00007471577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99682707,0.00007254451,0.00055923825,0.0014590353,0.0003417372,0.00074039184],"domain_scores_gemma":[0.9978597,0.000024846815,0.00019803365,0.0013635401,0.00025100049,0.00030288563],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036665745,0.0007623283,0.00050869054,0.000214468,0.0001262303,0.00029002517,0.00064798223,0.0008407122,0.000022707156],"category_scores_gemma":[0.00011446328,0.0008465957,0.00031262176,0.00026414555,0.000104123996,0.0000062525082,0.0012344541,0.0008196011,0.00006802879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002744974,0.0000844419,0.00015076184,0.0006034248,0.00016648363,0.000048090595,0.00000829325,0.0013989432,0.9962411,0.00006407416,0.0011953562,0.000011596039],"study_design_scores_gemma":[0.00031835723,0.00012043659,0.0009952472,0.00031812867,0.00016091701,7.2855954e-8,0.0000056474078,0.0006975021,0.9854884,0.000003980657,0.010898157,0.0009931212],"about_ca_topic_score_codex":0.000041467134,"about_ca_topic_score_gemma":0.0000070844712,"teacher_disagreement_score":0.05623563,"about_ca_system_score_codex":0.000077479934,"about_ca_system_score_gemma":0.0003044469,"threshold_uncertainty_score":0.99939847},"labels":[],"label_agreement":null},{"id":"W4405181965","doi":"10.1158/1538-8514.cancerchem24-ia003","title":"Abstract IA003: Synthetic lethality: Pathways to therapeutic discovery","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Synthetic lethality; Computational biology; Cancer; Context (archaeology); Drug discovery; Genome; Chromatin; Biology; CRISPR; DNA repair; Bioinformatics; DNA; Genetics; Gene","score_opus":0.02024564830007196,"score_gpt":0.3161788515262899,"score_spread":0.2959332032262179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405181965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.645938,0.055937923,0.29220238,0.0023066194,0.0014302855,0.00063799793,0.00011630354,0.00014618713,0.0012843403],"genre_scores_gemma":[0.9950315,0.0009195415,0.0003442858,0.0027156668,0.0003309576,0.00014512266,0.000031145588,0.000108773325,0.000373043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984294,0.00003760653,0.00026007116,0.0005789094,0.00025898305,0.0004349851],"domain_scores_gemma":[0.9991868,0.000017345215,0.00002705262,0.0005988279,0.00004920313,0.00012078694],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000195361,0.0003073886,0.00019258718,0.00008560653,0.00005938065,0.00018452696,0.00028714907,0.00016533936,0.000041870557],"category_scores_gemma":[0.000009320044,0.00028905508,0.0002062284,0.00021683308,0.00005112729,0.0000075592457,0.00009875464,0.00018188526,0.000041147454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034002136,0.000030624848,0.00006236281,0.00009190976,0.00030411725,0.000042666812,0.00020024057,0.00267,0.94168067,0.0010409851,0.00014837174,0.05369404],"study_design_scores_gemma":[0.00018589532,0.0001494895,0.0010123538,0.00013145861,0.00012212942,0.000025591362,0.000063774045,0.00045005462,0.82571876,0.0006711504,0.17093258,0.00053675304],"about_ca_topic_score_codex":0.0000321991,"about_ca_topic_score_gemma":0.000022979684,"teacher_disagreement_score":0.3490935,"about_ca_system_score_codex":0.000050094768,"about_ca_system_score_gemma":0.00015406852,"threshold_uncertainty_score":0.99995613},"labels":[],"label_agreement":null},{"id":"W4405221792","doi":"10.1093/nar/gkae1170","title":"Degradation and stable maintenance of adeno-associated virus inverted terminal repeats in <i>E. coli</i>","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Universität Bielefeld; Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst","keywords":"Biology; Adeno-associated virus; Long terminal repeat; Inverted repeat; Terminal (telecommunication); Degradation (telecommunications); Genetics; Virology; Genome; Gene; Recombinant DNA; Vector (molecular biology)","score_opus":0.023078043959939027,"score_gpt":0.3442567874671836,"score_spread":0.32117874350724457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405221792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996271,0.0020771723,0.0005060337,0.000105912666,0.00004719156,0.00014166324,0.000021619791,0.000011235074,0.00081817753],"genre_scores_gemma":[0.99749225,0.00088110863,0.00017853531,0.000017965192,0.000031578762,0.000014736363,0.000036174304,0.000017258237,0.001330391],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905723,0.00006886608,0.00015974703,0.00025161487,0.00020116147,0.0002613721],"domain_scores_gemma":[0.99965036,0.000027961576,0.0000129458695,0.00016541804,0.00009075781,0.000052543746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057140476,0.00007420945,0.00009920199,0.00012488257,0.00003528303,0.000029921213,0.00010579343,0.000110992114,0.000018039862],"category_scores_gemma":[0.00018270813,0.000072205024,0.000024273504,0.00030855002,0.00008892431,0.0000055830083,0.000103264734,0.0001796756,0.0000041816375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049123904,0.000034183824,0.0023618776,0.00008850758,0.000019526582,0.00001997659,0.00013536004,0.00003095015,0.98713213,0.00007458833,0.0033041842,0.006749598],"study_design_scores_gemma":[0.0009636557,0.00061155733,0.049555928,0.00039358332,0.000013339031,0.000032179174,0.0004515152,0.015521012,0.9045851,0.00033641318,0.02724801,0.0002876598],"about_ca_topic_score_codex":0.00016616276,"about_ca_topic_score_gemma":0.00021509765,"teacher_disagreement_score":0.08254697,"about_ca_system_score_codex":0.00003424798,"about_ca_system_score_gemma":0.00007593049,"threshold_uncertainty_score":0.29444352},"labels":[],"label_agreement":null},{"id":"W4405267611","doi":"10.1016/b978-0-323-95488-4.00155-8","title":"The Role of Biotransformation in Developmental Toxicity","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of Toronto","funders":"","keywords":"Biotransformation; Toxicity; Chemistry; Biochemistry; Organic chemistry","score_opus":0.005856957207308474,"score_gpt":0.23741451037553218,"score_spread":0.2315575531682237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405267611","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036404217,0.007661334,0.00001851973,0.000012273841,0.00011837663,0.00018850918,0.000019547124,0.0000060484717,0.98833495],"genre_scores_gemma":[0.19168785,0.00094280596,0.00018112929,0.000023522687,0.00012943547,0.000018746297,0.00005493878,0.00004378299,0.8069178],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994079,0.0000037016703,0.00024046737,0.00014692542,0.000089198526,0.00011183939],"domain_scores_gemma":[0.999784,0.0000057029074,0.000035202345,0.00013331066,0.00001888542,0.000022883269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010648753,0.00014107073,0.00011564255,0.00004064993,0.000024335357,0.0000114756485,0.00011651163,0.00016689877,0.0000070750707],"category_scores_gemma":[0.0000036736533,0.000111957306,0.000082584505,0.0000065504823,0.00004365121,6.0322355e-7,0.0000560712,0.00012269043,0.000012168082],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010386306,0.0000020327484,0.0000062398954,0.000050730298,0.000046326964,0.0000010018398,0.00011295793,0.000007921931,0.06873791,0.0016702804,0.000014934517,0.9293393],"study_design_scores_gemma":[0.0000594614,0.000026237869,0.0000141643395,0.00008875257,0.0000119443785,0.0000059981694,0.000025020727,0.000015005794,0.15978336,0.0020943321,0.8377572,0.0001185379],"about_ca_topic_score_codex":4.1025936e-7,"about_ca_topic_score_gemma":0.000099594174,"teacher_disagreement_score":0.92922074,"about_ca_system_score_codex":0.000018599483,"about_ca_system_score_gemma":0.000051657003,"threshold_uncertainty_score":0.45654863},"labels":[],"label_agreement":null},{"id":"W4405323257","doi":"10.1038/s44318-024-00337-5","title":"qTAG: an adaptable plasmid scaffold for CRISPR-based endogenous tagging","year":2024,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Institute of Cancer Research; Ministère de l’Éducation, Gouvernement de l’Ontario; Krembil Foundation; Canada Foundation for Innovation; Government of Ontario; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada","keywords":"Biology; CRISPR; Selectable marker; Computational biology; Plasmid; Context (archaeology); Protein tag; Cas9; Gene; Genetics; Fusion protein","score_opus":0.026767936381872994,"score_gpt":0.3166031963117604,"score_spread":0.28983525992988746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405323257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.639953,0.020564511,0.33317164,0.001526544,0.0020501628,0.00038312282,0.000051435447,0.00007992137,0.0022196404],"genre_scores_gemma":[0.9958985,0.000118730866,0.0019149344,0.00031781025,0.0012904897,0.000016409622,0.000020048583,0.000040785868,0.00038228926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992087,0.000029318951,0.00016491627,0.00017872358,0.00011443556,0.00030390316],"domain_scores_gemma":[0.99957144,0.000029367597,0.000028620689,0.00021951452,0.00004793648,0.00010314616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004163471,0.00013168372,0.00009618491,0.00004637861,0.00022180325,0.00015523653,0.00023677903,0.000056367015,0.000041119798],"category_scores_gemma":[0.00003016476,0.000095294185,0.00013332197,0.000059840517,0.000026820382,0.000005499785,0.000029751625,0.00014354054,0.000006901416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007029803,0.00003013754,0.000021293152,0.0000453625,0.00010408305,0.000023481205,0.00013618621,0.024145959,0.9623612,0.00019735139,0.007707933,0.0051567135],"study_design_scores_gemma":[0.0004486453,0.00040267757,0.000027393951,0.000050543393,0.000081009624,0.00070876064,0.00016381252,0.022756089,0.73368806,0.0003268073,0.24112879,0.00021741251],"about_ca_topic_score_codex":0.000004962433,"about_ca_topic_score_gemma":0.0000084767225,"teacher_disagreement_score":0.35594547,"about_ca_system_score_codex":0.000016141408,"about_ca_system_score_gemma":0.0001203225,"threshold_uncertainty_score":0.3885984},"labels":[],"label_agreement":null},{"id":"W4405419739","doi":"10.1038/s41587-024-02512-9","title":"CRISPR-StAR enables high-resolution genetic screening in complex in vivo models","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Terry Fox Research Institute; Krembil Foundation; Staatssekretariat für Bildung, Forschung und Innovation; Österreichischen Akademie der Wissenschaften; Canada Research Chairs","keywords":"CRISPR; Computational biology; Biology; Cas9; Genome; Bottleneck; Guide RNA; Genome editing; Genetics; Gene; Computer science","score_opus":0.008567904010227318,"score_gpt":0.2794367990180069,"score_spread":0.27086889500777955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405419739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87872624,0.03506639,0.08350933,0.0016163329,0.00036206463,0.00029137972,0.00004127815,0.0001592344,0.00022776687],"genre_scores_gemma":[0.9838769,0.0009791084,0.014682161,0.00012715408,0.0001262558,0.00002251626,0.00005151064,0.000032906417,0.00010151888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987249,0.000026593605,0.00023709034,0.0005264426,0.00009839406,0.0003866113],"domain_scores_gemma":[0.99957955,0.000011993481,0.000020447316,0.00033285233,0.000020158412,0.000034980818],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00012832659,0.00019296614,0.00018196461,0.00039627656,0.000026507527,0.000021013066,0.00024275917,0.0013106882,0.00002152528],"category_scores_gemma":[0.00004173563,0.00019953102,0.000054535747,0.00040976008,0.000071691575,0.000005088201,0.00015405029,0.0006480089,0.000003879296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035415575,0.00003170409,0.00024156665,0.00006617789,0.000026781481,0.000075511256,0.000030237696,0.03216009,0.95462614,0.0038946478,0.0019996024,0.0068121483],"study_design_scores_gemma":[0.0008533583,0.00023327798,0.004521827,0.00013544083,0.00001939431,0.00009617183,0.00011723506,0.16037132,0.7262236,0.0026257234,0.10420836,0.00059434236],"about_ca_topic_score_codex":0.00012769151,"about_ca_topic_score_gemma":0.0005487095,"teacher_disagreement_score":0.22840255,"about_ca_system_score_codex":0.000028274286,"about_ca_system_score_gemma":0.000034704677,"threshold_uncertainty_score":0.9999858},"labels":[],"label_agreement":null},{"id":"W4405467931","doi":"10.1038/s41573-024-01086-0","title":"Chemical engineering of CRISPR–Cas systems for therapeutic application","year":2024,"lang":"en","type":"review","venue":"Nature Reviews Drug Discovery","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"CRISPR; Cas9; Computational biology; Genome editing; Guide RNA; Biology; Computer science; Genetics; Gene","score_opus":0.013537187346259564,"score_gpt":0.3650077368407667,"score_spread":0.3514705494945071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405467931","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000025839272,0.95004654,0.04700217,0.000008557151,0.0007386515,0.0019893076,0.00016190844,0.000019069066,0.000031240295],"genre_scores_gemma":[0.00032379056,0.99619573,0.00029941954,0.000016472968,0.0009519254,0.00097554654,0.0007713534,0.00011442637,0.0003513209],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99823326,0.000039916227,0.0007556812,0.000584668,0.000135423,0.00025103166],"domain_scores_gemma":[0.9989597,0.000045680208,0.00024305297,0.0006477528,0.000047519676,0.00005626414],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003631507,0.0004950393,0.0014083972,0.000094262905,0.000015611186,0.000050646893,0.00036714287,0.00071666535,7.053406e-7],"category_scores_gemma":[0.00007889293,0.00036474995,0.0010308764,0.0002059188,0.000020516525,0.000005029476,0.00010377968,0.0004866708,0.000009495556],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012958691,0.00007388829,7.3205797e-7,0.33954906,0.0007261564,0.0000013180402,0.00002320595,0.00016004931,0.010107014,0.0014139306,0.017042037,0.63088965],"study_design_scores_gemma":[0.00006208361,0.000015609163,7.8005236e-8,0.0077520343,0.0011677368,0.000020419959,0.0000026278583,0.000108503526,0.0022434855,0.000005755086,0.9882692,0.0003524392],"about_ca_topic_score_codex":0.000001930713,"about_ca_topic_score_gemma":5.0730114e-7,"teacher_disagreement_score":0.97122717,"about_ca_system_score_codex":0.000045141736,"about_ca_system_score_gemma":0.000097945194,"threshold_uncertainty_score":0.99988043},"labels":[],"label_agreement":null},{"id":"W4405498081","doi":"10.7554/elife.100555","title":"Nonlinear transcriptional responses to gradual modulation of transcription factor dosage","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Human Genome Research Institute; Science for Life Laboratory; Knut och Alice Wallenbergs Stiftelse; Canadian Institutes of Health Research; European Commission","keywords":"Biology; Gene; Gene dosage; Chromatin; Gene expression; Genetics; Transcription factor; Computational biology; Regulation of gene expression; Histone; Enhancer","score_opus":0.02189587342405884,"score_gpt":0.32583086811861905,"score_spread":0.3039349946945602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405498081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96508944,0.002134756,0.030442735,0.00026271518,0.0008959182,0.00028188797,0.000777229,0.00003087326,0.00008444694],"genre_scores_gemma":[0.99444836,0.00021325695,0.0034208505,0.00006906216,0.0006108538,0.000032622163,0.00056809554,0.00004034864,0.0005965424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883467,0.000035130255,0.00031035216,0.00041138823,0.00025255446,0.00015592089],"domain_scores_gemma":[0.9994768,0.0000067967567,0.000039422914,0.0002999956,0.000091924994,0.00008508415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012240106,0.00021198973,0.00019436004,0.00012490053,0.000020392781,0.000022946091,0.000148195,0.0002723679,0.00002484039],"category_scores_gemma":[0.00003884571,0.0002230301,0.0002061022,0.00006841049,0.000023255752,0.0000012446427,0.000113759816,0.00021252094,0.000013270215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013897764,0.000035159283,0.000078607845,0.00021296562,0.00007263866,0.0000015316745,0.0002960253,0.007955719,0.98941493,0.000033503602,0.0004453876,0.0013145427],"study_design_scores_gemma":[0.00030595332,0.00027062034,0.01563018,0.00017645983,0.00006808509,0.0000063208427,0.0000394503,0.0036574164,0.9601993,0.00015842904,0.019065568,0.0004222072],"about_ca_topic_score_codex":0.000022235137,"about_ca_topic_score_gemma":0.00002481218,"teacher_disagreement_score":0.029358929,"about_ca_system_score_codex":0.000019748994,"about_ca_system_score_gemma":0.00011151143,"threshold_uncertainty_score":0.90949035},"labels":[],"label_agreement":null},{"id":"W4405523790","doi":"10.1371/journal.pone.0315923","title":"GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens","year":2024,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Western University","funders":"Cancer Research Society","keywords":"CRISPR; Computational biology; Workflow; Function (biology); Biology; Gene; Genetics; Computer science; Database","score_opus":0.01436666124320494,"score_gpt":0.27284710280686364,"score_spread":0.2584804415636587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405523790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9646149,0.0018533416,0.03230579,0.0002866668,0.00015612868,0.00036052818,0.00003078037,0.000022511425,0.00036930022],"genre_scores_gemma":[0.99665415,0.00015255284,0.0020624916,0.000071647824,0.0002785544,0.000051877592,0.000055929166,0.000022970966,0.0006498162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908966,0.000026677639,0.00024315815,0.00029329944,0.00015718676,0.00019002178],"domain_scores_gemma":[0.99959844,0.00001621257,0.000020682137,0.0002573694,0.00004239756,0.000064923515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001542145,0.00012551378,0.00024170312,0.000080055295,0.000015353484,0.00002613177,0.000089944675,0.00009215329,0.000028703422],"category_scores_gemma":[0.0000655163,0.000119651544,0.00009096893,0.00017249046,0.000021560169,0.0000036339845,0.00006660124,0.00007858364,0.000021605862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041193224,0.0002694298,0.002551731,0.00011221974,0.000273287,0.000006451623,0.000035991892,0.00069893297,0.994675,0.0001044294,0.00023749964,0.00062308443],"study_design_scores_gemma":[0.0014285933,0.0002556891,0.005598935,0.00018895467,0.00015983013,0.0000015619522,0.0000141680075,0.0013104674,0.98958063,0.00013113528,0.0011152424,0.00021481744],"about_ca_topic_score_codex":0.000032622553,"about_ca_topic_score_gemma":0.000080089965,"teacher_disagreement_score":0.032039203,"about_ca_system_score_codex":0.00001456704,"about_ca_system_score_gemma":0.000036291534,"threshold_uncertainty_score":0.48792484},"labels":[],"label_agreement":null},{"id":"W4405573668","doi":"10.3390/app142411893","title":"Can Digital Activism Change Sustainable Supply Chain Practices in the Agricultural Bioeconomy? Evidence from #Buttergate","year":2024,"lang":"en","type":"article","venue":"Applied Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"Social Sciences and Humanities Research Council of Canada","keywords":"Supply chain; Business; Agriculture; Political science; Marketing; Geography","score_opus":0.024297458555672346,"score_gpt":0.30710476057589897,"score_spread":0.28280730202022664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405573668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99095654,0.0028147106,0.00018918935,0.0035730996,0.00010769438,0.00025102406,0.000012063046,0.000016388916,0.002079313],"genre_scores_gemma":[0.99896264,0.00015347592,0.00008675054,0.00017907105,0.0002970278,0.00010202407,0.000021985416,0.0000052205974,0.00019179066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999112,0.000015850479,0.000101441925,0.00036935465,0.00012637029,0.00027498195],"domain_scores_gemma":[0.9996902,0.00008398615,0.000041341937,0.00014126534,0.000011364583,0.00003188642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032863513,0.000111538335,0.00007162034,0.000042292257,0.00009784772,0.00043472918,0.00036018708,0.000047310874,0.00000870736],"category_scores_gemma":[0.000049664555,0.000069336325,0.000030576437,0.0002442336,0.00010959547,0.00003668173,0.00009673534,0.000085788844,0.000009146209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033372187,0.00007039143,0.0072389687,0.000114368246,0.00006204221,0.000056624736,0.011175396,0.00053765404,0.9515809,0.0034814302,0.0027449285,0.022903943],"study_design_scores_gemma":[0.0006791579,0.00085313723,0.13312809,0.0003343084,0.00008361004,0.000103045975,0.10286484,0.00291443,0.62874347,0.003549634,0.12486073,0.0018855821],"about_ca_topic_score_codex":0.00034132996,"about_ca_topic_score_gemma":0.0002179357,"teacher_disagreement_score":0.32283744,"about_ca_system_score_codex":0.0000135397795,"about_ca_system_score_gemma":0.00005232447,"threshold_uncertainty_score":0.41921034},"labels":[],"label_agreement":null},{"id":"W4405580638","doi":"10.1038/s41587-024-02516-5","title":"NIS-Seq enables cell-type-agnostic optical perturbation screening","year":2024,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Infection and Immunity; Leibniz-Gemeinschaft; Deutsche Forschungsgemeinschaft; Rheinische Friedrich-Wilhelms-Universität Bonn; Melanoma Research Alliance","keywords":"Biology; Computational biology; RNA; Subgenomic mRNA; Guide RNA; Single-cell analysis; Genomic library; Cell; Cell biology; Genome; Genetics; DNA; Gene; Genome editing; Base sequence","score_opus":0.003974672727147771,"score_gpt":0.2726240223347687,"score_spread":0.2686493496076209,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405580638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6377084,0.12481593,0.22122146,0.006668367,0.003145487,0.0004718699,0.00003028781,0.0008049196,0.005133262],"genre_scores_gemma":[0.9912908,0.0007960296,0.0057654884,0.00017698883,0.00036153503,0.000008222514,0.000093553674,0.00003404775,0.0014733474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990467,0.000009591495,0.00013655766,0.00043273086,0.00009830335,0.00027610923],"domain_scores_gemma":[0.9995553,0.000029739234,0.000015629128,0.00030997006,0.000040779345,0.000048622023],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00009266352,0.0001668091,0.0001163091,0.00013240932,0.000051259973,0.00003435509,0.00019727716,0.0013897456,0.000024702118],"category_scores_gemma":[0.00021057557,0.0001542378,0.00006731706,0.00023794196,0.00007414566,0.0000030221695,0.00012207477,0.00059153687,0.0000295901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001665915,0.000015617794,0.000042235333,0.000051438994,0.00003247377,0.000023960996,0.00001032123,0.00027766507,0.98058045,0.0030357954,0.0040213065,0.01189206],"study_design_scores_gemma":[0.000117428775,0.00017957193,0.00011823975,0.000025628666,0.00002352047,0.00006603803,0.000024350928,0.0010842909,0.81637293,0.00023594487,0.18157476,0.00017727856],"about_ca_topic_score_codex":0.0000020034945,"about_ca_topic_score_gemma":0.000004277147,"teacher_disagreement_score":0.35358238,"about_ca_system_score_codex":0.0000120330105,"about_ca_system_score_gemma":0.00004065258,"threshold_uncertainty_score":0.99990666},"labels":[],"label_agreement":null},{"id":"W4405751773","doi":"10.1016/j.jval.2024.10.2046","title":"HTA221 Market Access Challenges for Gene Therapies in Inherited Blood Disorders: A Retrospective Evaluation of HTA Outcomes for Sickle Cell Disease and Thalassemia","year":2024,"lang":"en","type":"article","venue":"Value in Health","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"EVERSANA (Canada)","funders":"","keywords":"Medicine; Thalassemia; Disease; Intensive care medicine; Pediatrics; Internal medicine","score_opus":0.03847742794805487,"score_gpt":0.3742099856130437,"score_spread":0.33573255766498883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405751773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92368877,0.072920546,0.001110647,0.0009589444,0.000113316935,0.0010749218,0.0000899958,0.000008104073,0.000034766545],"genre_scores_gemma":[0.9890173,0.009904046,0.00062993704,0.000024124434,0.0000541474,0.00028472548,0.0000379062,0.000022153814,0.000025655418],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99912673,0.000076542354,0.00022285913,0.0002939809,0.000103745,0.00017616389],"domain_scores_gemma":[0.9996385,0.0000781112,0.000042163065,0.00014889297,0.000045788463,0.000046564786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008075393,0.0001098793,0.00016813683,0.00008816254,0.000019284003,0.000015711348,0.000075844655,0.00006151013,0.00000258568],"category_scores_gemma":[0.00012805643,0.00010411951,0.00005042773,0.00007959529,0.000019014708,0.000005985012,0.00003435948,0.00004598539,3.817968e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00173791,0.0022086531,0.61202043,0.026874093,0.0008989061,0.00000599038,0.011298615,0.04744881,0.1902418,0.0017580149,0.0012028292,0.10430398],"study_design_scores_gemma":[0.004394964,0.00096102536,0.8599905,0.00042899564,0.00011927845,0.0000015778031,0.00065117877,0.09979017,0.023748133,0.008093495,0.0014019553,0.00041874716],"about_ca_topic_score_codex":0.00011323812,"about_ca_topic_score_gemma":0.00024779883,"teacher_disagreement_score":0.24797007,"about_ca_system_score_codex":0.00003256196,"about_ca_system_score_gemma":0.00014018605,"threshold_uncertainty_score":0.42458704},"labels":[],"label_agreement":null},{"id":"W4405803075","doi":"10.1158/1078-0432.ccr-24-2729","title":"Challenges to Innovation Arising from Current Companion Diagnostic Regulations and Suggestions for Improvements","year":2024,"lang":"en","type":"editorial","venue":"Clinical Cancer Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Astellas Pharma; Regeneron Pharmaceuticals; International Association for the Study of Lung Cancer; Eisai; Daiichi Sankyo Europe; Sanofi; Genentech; Celgene; Bristol-Myers Squibb; AstraZeneca; Amgen; Pfizer","keywords":"Flexibility (engineering); Companion diagnostic; Risk analysis (engineering); Diagnostic test; Quality (philosophy); Consistency (knowledge bases); Medicine; Clinical trial; Diagnostic accuracy; Unintended consequences; Medical physics; Precision medicine; New product development; Business; Computer science; Marketing; Pathology; Cancer","score_opus":0.16174615951432111,"score_gpt":0.5629987054769863,"score_spread":0.40125254596266513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405803075","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.059017666,0.08180154,0.014424274,0.0028473332,0.8367985,0.002292787,0.0026812898,0.00004793338,0.00008869331],"genre_scores_gemma":[0.07935294,0.043010958,0.0008167832,0.000029239109,0.8711003,0.00131707,0.003772455,0.00010898785,0.0004912504],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99802226,0.00009131111,0.0004652007,0.00074593304,0.00038046364,0.00029485134],"domain_scores_gemma":[0.99706286,0.001667924,0.000052103616,0.00034803603,0.00074891426,0.000120186916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012654118,0.00016278135,0.00023319059,0.00015917665,0.00011385217,0.00008394229,0.0001832687,0.00046119254,0.000006591552],"category_scores_gemma":[0.007163021,0.00016436861,0.00006865031,0.00020130898,0.00007902918,0.0000026020018,0.00031544958,0.0007075822,0.00000674224],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051638453,0.000054998174,0.00009190793,0.00025842068,0.00008063596,4.275537e-7,0.000040964926,0.00007677646,0.003183891,0.00007512724,0.84570104,0.15038419],"study_design_scores_gemma":[0.00040292798,0.00031130324,0.0022599355,0.00049475767,0.000048074773,6.8843825e-8,0.000024648902,0.00016137052,0.0010383769,0.0008962682,0.994168,0.00019427437],"about_ca_topic_score_codex":0.000103127386,"about_ca_topic_score_gemma":0.00035631756,"teacher_disagreement_score":0.1501899,"about_ca_system_score_codex":0.00005679873,"about_ca_system_score_gemma":0.00033341325,"threshold_uncertainty_score":0.85753226},"labels":[],"label_agreement":null},{"id":"W4405851924","doi":"10.5376/gab.2024.15.0020","title":"Genome Editing and Rice Improvement: The Role of CRISPR/Cas9 in Developing Superior Yield Traits","year":2024,"lang":"en","type":"article","venue":"Genomics and Applied Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Genome editing; Yield (engineering); Biology; Genetics; Biotechnology; Computational biology; Gene","score_opus":0.005594737904058873,"score_gpt":0.24943515636508132,"score_spread":0.24384041846102245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405851924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98658794,0.009741649,0.0028724333,0.0001533695,0.00006723029,0.0001471007,0.0000207202,0.000005718795,0.00040382615],"genre_scores_gemma":[0.9977083,0.001320459,0.00060877827,0.00010559403,0.00019201082,0.000020811814,0.000019083012,0.00001265493,0.0000122695255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936634,0.0000062346257,0.00017287483,0.0002517411,0.000020177597,0.00018265625],"domain_scores_gemma":[0.9998412,0.00002224632,0.00002099676,0.00008028334,0.000008958839,0.000026293634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015210349,0.000107518805,0.00012100532,0.000038588787,0.00004003308,0.000019014238,0.0000790398,0.00010265283,0.0000022016313],"category_scores_gemma":[0.000007872158,0.00008457548,0.000020925143,0.00005356558,0.000064662134,0.0000012026201,0.0001271013,0.00007855807,5.332086e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008359491,0.0000031680781,0.0001458026,0.000039298633,0.000021891794,3.8884323e-7,0.00020484868,0.000028976983,0.9786855,0.00264623,0.0000029266564,0.018212592],"study_design_scores_gemma":[0.0002721436,0.00014709501,0.010750003,0.000018784827,0.000021108588,0.000025062807,0.0010068932,0.00028959484,0.92624706,0.0013022317,0.059661828,0.00025821294],"about_ca_topic_score_codex":0.000016009719,"about_ca_topic_score_gemma":0.000027504675,"teacher_disagreement_score":0.0596589,"about_ca_system_score_codex":0.0000070554916,"about_ca_system_score_gemma":0.000027376154,"threshold_uncertainty_score":0.34488878},"labels":[],"label_agreement":null},{"id":"W4405868773","doi":"10.1101/2024.12.27.630546","title":"Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Genentech","keywords":"CRISPR; Electronic circuit; Dynamic range; Genome editing; Computational biology; Gene; Perturbation (astronomy); Genetics; Biology; Physics; Computer science; Quantum mechanics; Optics","score_opus":0.008698597850455753,"score_gpt":0.2516028252856609,"score_spread":0.24290422743520515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405868773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9394984,0.00946935,0.045844495,0.00027865675,0.0024773302,0.0013186951,0.0008256228,0.0002636405,0.000023813493],"genre_scores_gemma":[0.9924094,0.00075807265,0.0045547457,0.00015975226,0.0011776274,0.00058817345,0.000018205881,0.0002606072,0.0000734153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99709255,0.000038487502,0.0005119847,0.0014547152,0.0002642125,0.0006380385],"domain_scores_gemma":[0.99789304,0.00002956807,0.00016963793,0.0012717347,0.0003917574,0.00024424944],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038741058,0.0006522687,0.00048366617,0.00018120126,0.000106646636,0.00017214585,0.0005184799,0.0009482275,0.000017637474],"category_scores_gemma":[0.00023928602,0.00073284254,0.00032170254,0.00022535074,0.000064585256,0.0000061163187,0.00034984358,0.0005446341,0.000032043237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000249382,0.00006013347,0.00008264439,0.0007917358,0.00023219225,0.000009892887,0.000007572245,0.00040054915,0.9973625,0.000098547935,0.0009175054,0.000011810271],"study_design_scores_gemma":[0.00055288704,0.00009663475,0.001951605,0.00019464218,0.00021959913,1.1687711e-7,0.0000022402082,0.0009264582,0.98891234,0.000018171784,0.006248286,0.0008770229],"about_ca_topic_score_codex":0.000015868656,"about_ca_topic_score_gemma":0.0000030363628,"teacher_disagreement_score":0.052911002,"about_ca_system_score_codex":0.00014794192,"about_ca_system_score_gemma":0.0003855764,"threshold_uncertainty_score":0.99951226},"labels":[],"label_agreement":null},{"id":"W4405878015","doi":"10.1186/s12934-024-02634-4","title":"A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440","year":2024,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; National Key Research and Development Program of China; University of Waterloo","keywords":"CRISPR; Pseudomonas putida; Genome editing; Cas9; Plasmid; Biology; Computational biology; Genome; Genetics; Bacteria; Gene","score_opus":0.009507286096945108,"score_gpt":0.2525495378837771,"score_spread":0.24304225178683198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405878015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8938133,0.011602251,0.08880701,0.00014744989,0.0030145934,0.00085659773,0.0006422375,0.00014166214,0.0009748949],"genre_scores_gemma":[0.9963178,0.00003087508,0.0017710112,0.000046931997,0.00089357496,0.00006075105,0.00036636807,0.00006212341,0.00045057252],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857134,0.000038251706,0.0003266421,0.00052157685,0.000094839124,0.0004473264],"domain_scores_gemma":[0.9995117,0.000053415468,0.000047454956,0.00022489186,0.00008462596,0.0000778774],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001439822,0.00029415503,0.00024822654,0.00010741757,0.000103027465,0.00018464346,0.00016590174,0.00019534516,0.00001711642],"category_scores_gemma":[0.000033891036,0.00029804689,0.00015935472,0.00015616688,0.000052620937,0.00001172256,0.000060032966,0.00014721524,0.0000122664405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006398404,0.00003733655,0.00011695459,0.00070840726,0.00003068271,0.000019102792,0.00039283227,0.0016806329,0.9952759,0.000027519409,0.0012990622,0.0003475941],"study_design_scores_gemma":[0.0004883793,0.00020858299,0.000028573559,0.00011359958,0.00002324796,0.000016947315,0.00035007406,0.0004982232,0.86217916,0.0000050809053,0.13579647,0.0002916851],"about_ca_topic_score_codex":0.00003528962,"about_ca_topic_score_gemma":0.000056121367,"teacher_disagreement_score":0.1344974,"about_ca_system_score_codex":0.000095820076,"about_ca_system_score_gemma":0.00010914592,"threshold_uncertainty_score":0.9999472},"labels":[],"label_agreement":null},{"id":"W4405896537","doi":"10.1073/pnas.2413519121","title":"Mechanism-guided engineering of a minimal biological particle for genome editing","year":2024,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Lawrence Livermore National Laboratory; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Parker Institute for Cancer Immunotherapy; Alexander von Humboldt-Stiftung; National Cancer Institute; National Institutes of Health; National Heart, Lung, and Blood Institute; European Molecular Biology Organization","keywords":"Genome editing; Cas9; Ribonucleoprotein; Genome; Computational biology; CRISPR; Capsid; Genome engineering; Guide RNA; Biology; Cell biology; Computer science; Gene; RNA; Genetics","score_opus":0.03871776268091414,"score_gpt":0.33416747863295904,"score_spread":0.2954497159520449,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405896537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99848354,0.0004943546,0.0004049344,0.00031959085,0.000029054318,0.00010227961,0.000018520608,0.000005803077,0.00014193844],"genre_scores_gemma":[0.9949474,0.000020854643,0.0048178392,0.00002143458,0.00015394826,0.000010952033,3.003537e-7,0.000003342016,0.000023952021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993798,0.0000010762084,0.00018473901,0.00014352943,0.0001912419,0.000099621866],"domain_scores_gemma":[0.99980366,0.000028990193,0.00006030382,0.0000049909777,0.000085631975,0.000016407073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052948575,0.00005252864,0.00007461444,0.000037131253,0.000030218122,0.000007926563,0.00022902957,0.00005543633,0.0000022593797],"category_scores_gemma":[0.00032312347,0.000036625454,0.000069223126,0.000173273,0.00010537586,0.0000073843967,0.00007349983,0.000036883168,1.0482219e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000037841085,0.0000063993093,0.00015330342,0.00008349985,0.000011998943,1.6393658e-9,0.000034154084,0.0006391113,0.9821178,0.016815826,0.000063373984,0.00007075555],"study_design_scores_gemma":[0.00005933745,0.00007822041,0.0020548326,0.00003599948,0.0000060542643,0.0000043279624,0.00005054616,0.009919127,0.9851128,0.002259663,0.00037711055,0.000041970572],"about_ca_topic_score_codex":4.0816602e-7,"about_ca_topic_score_gemma":6.9859833e-9,"teacher_disagreement_score":0.014556163,"about_ca_system_score_codex":0.0000045248107,"about_ca_system_score_gemma":0.000012309969,"threshold_uncertainty_score":0.14935428},"labels":[],"label_agreement":null},{"id":"W4405909880","doi":"10.1371/journal.pone.0316331","title":"Evidence for gene essentiality in Leishmania using CRISPR","year":2024,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Leishmania; Biology; Gene; Genetics; Computational biology; Computer science; Parasite hosting","score_opus":0.10353362353883681,"score_gpt":0.362520938153302,"score_spread":0.25898731461446517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405909880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93308866,0.009149848,0.05731311,0.00009534244,0.00009606248,0.00019479604,0.0000115257535,0.00001771283,0.000032924167],"genre_scores_gemma":[0.9879847,0.0003648159,0.011058856,0.000034711025,0.00033141748,0.00002742228,0.000018630548,0.000020084912,0.00015935539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993655,0.000011756818,0.0001294903,0.00025020176,0.00008120394,0.00016186407],"domain_scores_gemma":[0.9997326,0.000019209912,0.000010393949,0.00017278382,0.000031850697,0.000033160904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014525498,0.000081693695,0.00009637249,0.000035670153,0.00002082786,0.000031929587,0.00008205179,0.00006734242,0.000011473779],"category_scores_gemma":[0.0000926804,0.000088607856,0.00004639334,0.00007254718,0.000014399227,0.000003603588,0.00004727536,0.000049936913,0.0000035764633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018321816,0.00007074864,0.0007941923,0.00025754797,0.000054021577,0.0000029649639,0.000026654503,0.00025456052,0.99811757,0.000018812965,0.00006636144,0.0003182256],"study_design_scores_gemma":[0.00011573558,0.000053050386,0.00086075655,0.0002572923,0.000052272968,0.0000023630525,0.0000096778585,0.008865918,0.9892739,0.000053752028,0.00033746325,0.00011778991],"about_ca_topic_score_codex":0.000027873182,"about_ca_topic_score_gemma":0.000031053587,"teacher_disagreement_score":0.05489603,"about_ca_system_score_codex":0.000015567688,"about_ca_system_score_gemma":0.000038404407,"threshold_uncertainty_score":0.36133233},"labels":[],"label_agreement":null},{"id":"W4405910570","doi":"10.1093/bioadv/vbae184","title":"Predicting CRISPR-Cas9 off-target effects in human primary cells using bidirectional LSTM with BERT embedding","year":2024,"lang":"en","type":"article","venue":"Bioinformatics Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; National Research Council Canada; McGill University","funders":"National Research Council Canada","keywords":"CRISPR; Embedding; Primary (astronomy); Computer science; Computational biology; Biology; Artificial intelligence; Genetics; Gene; Physics","score_opus":0.004768933118316525,"score_gpt":0.2879238221660577,"score_spread":0.2831548890477412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405910570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85684264,0.013832256,0.12482222,0.000012244741,0.00066270493,0.00027322827,0.000022931057,0.000085202024,0.003446573],"genre_scores_gemma":[0.9284951,0.00043013445,0.07025481,0.00006840391,0.0003490994,0.000027484259,0.000093391594,0.000045694716,0.00023586904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990521,0.000012766456,0.00028746715,0.00020174251,0.00016958942,0.00027634396],"domain_scores_gemma":[0.9996699,0.000032158794,0.00005353951,0.00015545382,0.0000293112,0.0000596441],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014979175,0.00018872932,0.00015903226,0.00012673798,0.0000896742,0.0000679433,0.000103575185,0.00008477353,0.0000052013993],"category_scores_gemma":[0.000018232498,0.00016599211,0.000054502256,0.00017520775,0.00003960133,0.00003495581,0.00006817904,0.00012635384,0.0000028448337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005055763,0.000063576284,0.007573706,0.002587584,0.0001410722,0.00003208904,0.0006760165,0.2601697,0.7004493,0.000090602436,0.00036387178,0.027801892],"study_design_scores_gemma":[0.0006927984,0.000448217,0.0016143122,0.00085061806,0.000053024654,0.000102511905,0.00036406994,0.4145714,0.54290307,0.000080297934,0.037652373,0.00066732714],"about_ca_topic_score_codex":0.000008518764,"about_ca_topic_score_gemma":0.000018363395,"teacher_disagreement_score":0.15754627,"about_ca_system_score_codex":0.000042081614,"about_ca_system_score_gemma":0.000060921873,"threshold_uncertainty_score":0.67689615},"labels":[],"label_agreement":null},{"id":"W4405979343","doi":"10.1101/2024.12.20.629823","title":"Stress-driven emergence of heritable non-genetic drug resistance","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Toronto","funders":"School of Medicine, Stanford University; Universidade de Macau; Crohn's and Colitis Foundation; Damon Runyon Cancer Research Foundation; National Institutes of Health; National Science Foundation","keywords":"Resistance (ecology); Drug; Genetics; Stress (linguistics); Drug resistance; Biology; Evolutionary biology; Pharmacology; Ecology; Philosophy","score_opus":0.005455332361668216,"score_gpt":0.23579154352010037,"score_spread":0.23033621115843217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405979343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9752718,0.016371844,0.0053890673,0.000096027594,0.0016147372,0.0005964222,0.00048676156,0.000099137294,0.00007420016],"genre_scores_gemma":[0.9878144,0.0012346372,0.009994906,0.000027272035,0.00049454265,0.00013970364,0.0000015879679,0.00015239572,0.00014052769],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997594,0.00004586143,0.0005608083,0.0010223067,0.00029034348,0.00048669038],"domain_scores_gemma":[0.99788105,0.000011131054,0.00020827755,0.0014177745,0.00029457643,0.00018715634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001972631,0.00051107624,0.00045847634,0.00013382846,0.00006022025,0.00006511305,0.0006406292,0.00040837197,0.0000369055],"category_scores_gemma":[0.00006934616,0.0005751364,0.00022354686,0.0002888585,0.00010466406,0.0000035411163,0.0009331981,0.00044466034,0.00002583295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021208592,0.00005688615,0.0016725383,0.001530016,0.00018834337,0.000023419127,0.000011925281,0.003086116,0.98977214,0.000038489987,0.0035974777,0.0000014646945],"study_design_scores_gemma":[0.00019565225,0.000035019195,0.009525026,0.0006000453,0.000117327094,1.520037e-8,0.0000067786236,0.00050632714,0.9817941,0.00000448054,0.006547824,0.0006673666],"about_ca_topic_score_codex":0.000034208962,"about_ca_topic_score_gemma":0.00002841927,"teacher_disagreement_score":0.015137208,"about_ca_system_score_codex":0.000031940133,"about_ca_system_score_gemma":0.00037287362,"threshold_uncertainty_score":0.99967},"labels":[],"label_agreement":null},{"id":"W4406076710","doi":"10.1093/aobpla/plae074","title":"Taming the wild: domesticating untapped northern fruit tree and shrub resources in the era of high-throughput technologies","year":2024,"lang":"en","type":"review","venue":"AoB Plants","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Grain Research Centre","funders":"","keywords":"Biology; Shrub; Tree (set theory); Agroforestry; Ecology","score_opus":0.013768531793417834,"score_gpt":0.3140237918779349,"score_spread":0.30025526008451703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406076710","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022979638,0.9762525,0.00007094902,0.000104833736,0.00007478789,0.00030644768,0.00006176413,0.000021050964,0.00012805879],"genre_scores_gemma":[0.10277877,0.89680165,0.00013607054,0.000015952526,0.00008469302,0.000052211497,0.0000668714,0.000026669433,0.000037143822],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99898046,0.000055965636,0.00031773755,0.00032887192,0.000115689894,0.00020124343],"domain_scores_gemma":[0.99928695,0.0001233347,0.00010485304,0.00046304555,0.000009453483,0.000012375047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022393293,0.00024556814,0.00042858385,0.00005250831,0.000049672148,0.000034608744,0.00046124545,0.0002416255,7.379114e-7],"category_scores_gemma":[0.000087676715,0.00013022352,0.00009059717,0.00014822169,0.00010845795,0.0000014492765,0.00024563796,0.00037007165,0.0000034465163],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029837547,0.000009528752,0.000056287423,0.0017427871,0.00009617866,0.000010815188,0.00043748808,0.000010531933,0.00014024093,0.000020664835,0.000163595,0.9973089],"study_design_scores_gemma":[0.00016547854,0.00011658915,0.00019698423,0.006139512,0.00043787956,0.0001868379,0.0018217379,0.000028561228,0.00051328127,0.00014179619,0.9898414,0.00040996936],"about_ca_topic_score_codex":0.00009811507,"about_ca_topic_score_gemma":0.00033170683,"teacher_disagreement_score":0.99689895,"about_ca_system_score_codex":0.000008309313,"about_ca_system_score_gemma":0.0000349292,"threshold_uncertainty_score":0.5310361},"labels":[],"label_agreement":null},{"id":"W4406143805","doi":"10.1073/pnas.2419712122","title":"The single-stranded DNA–binding factor SUB1/PC4 alleviates replication stress at telomeres and is a vulnerability of ALT cancer cells","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Alliance de recherche numérique du Canada; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Telomere; Telomerase; Cell biology; Chromatin; DNA damage; Biology; Homologous recombination; Cancer cell; Chemistry; DNA; Genetics; Cancer; Gene","score_opus":0.026254691078262102,"score_gpt":0.34634654361655653,"score_spread":0.3200918525382944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406143805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99729794,0.0008258507,0.0000041214385,0.0012846634,0.000015756093,0.00012606393,0.000046340283,0.00000212073,0.00039713198],"genre_scores_gemma":[0.99917,0.0003804164,0.0001353889,0.000042784406,0.00002101537,0.000009326312,3.2760835e-7,0.0000020263667,0.0002387219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922913,0.000004536218,0.0002090852,0.00021296687,0.0002538901,0.0000903617],"domain_scores_gemma":[0.99958175,0.00005865844,0.00017404958,0.000018889774,0.00015117537,0.000015487021],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041416782,0.000065065404,0.000085645355,0.000036262132,0.00015396399,0.000013227767,0.00030735918,0.00006128125,0.0000034097852],"category_scores_gemma":[0.00022447959,0.000040562885,0.00004172094,0.00017875672,0.00040264495,0.000009001524,0.00012363108,0.000049331855,3.685884e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014687937,0.0000129532555,0.012475732,0.00007585701,0.00001861271,2.5654187e-10,0.00008027488,0.00005507428,0.98575956,0.00023867594,0.0002300907,0.0010384636],"study_design_scores_gemma":[0.000088186694,0.00002294595,0.0449369,0.000046099933,0.00000816453,3.1345286e-7,0.000092343354,0.00020253134,0.95346624,0.00071620214,0.00038051364,0.0000395686],"about_ca_topic_score_codex":0.0000073200686,"about_ca_topic_score_gemma":0.0000015038609,"teacher_disagreement_score":0.032461166,"about_ca_system_score_codex":0.000013895213,"about_ca_system_score_gemma":0.000020686215,"threshold_uncertainty_score":0.16541065},"labels":[],"label_agreement":null},{"id":"W4406205497","doi":"10.1016/j.ymthe.2025.01.013","title":"Focused ultrasound and microbubble-mediated delivery of CRISPR-Cas9 ribonucleoprotein to human induced pluripotent stem cells","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Canadian Institutes of Health Research; Concordia University; Canadian Aeronautics and Space Institute; Canada Research Chairs; Burroughs Wellcome Fund","keywords":"Ribonucleoprotein; CRISPR; Induced pluripotent stem cell; Cell biology; Stem cell; Human Induced Pluripotent Stem Cells; Genome editing; Cas9; Biology; Embryonic stem cell; RNA; Genetics; Gene","score_opus":0.008247263032740254,"score_gpt":0.2668046783325718,"score_spread":0.25855741529983156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406205497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98230696,0.0029447058,0.013960085,0.00008399087,0.000091047434,0.00046846305,0.00001753695,0.00001810149,0.0001091009],"genre_scores_gemma":[0.99812806,0.0002583685,0.00084144145,0.00048793596,0.000024057936,0.00003088464,0.000023181452,0.00003135725,0.00017473081],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989631,0.0000511324,0.00025649977,0.00037387508,0.00011089486,0.00024447608],"domain_scores_gemma":[0.9993542,0.000013014049,0.000049358045,0.00040493236,0.00008817995,0.00009031836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011111027,0.00021076605,0.00021439111,0.00011160229,0.00005644168,0.00002584739,0.00018598187,0.00015768709,0.000008312138],"category_scores_gemma":[0.000009419012,0.00021582746,0.00009189998,0.0001695286,0.00003763847,0.0000021876172,0.00008094672,0.00008749142,0.0000032871949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000795427,0.00005645798,0.0002626762,0.000030183463,0.00012827003,0.0000055272694,0.000079159065,0.00017338162,0.99342126,0.000027314616,0.00017599335,0.0055602347],"study_design_scores_gemma":[0.0010702192,0.0003417204,0.0011754285,0.000033727,0.000015749129,0.000002789435,0.000059538026,0.000015068524,0.9915834,0.000025151876,0.005466709,0.00021051314],"about_ca_topic_score_codex":0.00007748153,"about_ca_topic_score_gemma":0.000021363803,"teacher_disagreement_score":0.015821073,"about_ca_system_score_codex":0.0000130702365,"about_ca_system_score_gemma":0.00003774198,"threshold_uncertainty_score":0.88011885},"labels":[],"label_agreement":null},{"id":"W4406236145","doi":"10.1101/2025.01.09.632232","title":"A comparative evaluation of CRISPR-Cas9 allele editing systems in <i>Candida auris</i> : challenging research in a challenging bug","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Novelis (Canada)","funders":"National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences; National Institutes of Health; Vlaamse regering; Joint Programming Initiative on Antimicrobial Resistance; KU Leuven; Fonds Wetenschappelijk Onderzoek","keywords":"CRISPR; Candida auris; Genome editing; Biology; Allele; Genetics; Computational biology; Antifungal; Microbiology; Gene","score_opus":0.05155324144152844,"score_gpt":0.3598425800863589,"score_spread":0.30828933864483044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406236145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.967046,0.025989816,0.00396418,0.000104654224,0.00086358114,0.0017223475,0.000100121295,0.00004628544,0.00016296843],"genre_scores_gemma":[0.99745864,0.0009468948,0.00037065588,0.000010682212,0.0004979825,0.00065094815,0.0000030737147,0.00005655278,0.000004565772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99590427,0.0006148557,0.00086272164,0.001086834,0.00078070554,0.0007506427],"domain_scores_gemma":[0.997614,0.00008863305,0.00026101916,0.0009752334,0.0009365214,0.000124547],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004462259,0.0004639025,0.0007499974,0.0008897145,0.00009707296,0.000074186755,0.0005217114,0.0006146644,0.0000054375514],"category_scores_gemma":[0.00030116332,0.00056782016,0.00012169783,0.00071796105,0.00008635143,0.000011915259,0.00066843274,0.0009976776,0.0000030731862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009563506,0.0002881567,0.005567565,0.0022742029,0.0002394973,0.000027499906,0.00028406634,0.22469056,0.7660079,0.00024136617,0.00026893264,0.000014644519],"study_design_scores_gemma":[0.0030244219,0.00021871924,0.036019966,0.005476141,0.00014114118,1.0172326e-7,0.000727539,0.15114434,0.7996403,0.000007414501,0.0022307988,0.001369143],"about_ca_topic_score_codex":0.00040884575,"about_ca_topic_score_gemma":0.00008733375,"teacher_disagreement_score":0.07354621,"about_ca_system_score_codex":0.00034001266,"about_ca_system_score_gemma":0.0007337734,"threshold_uncertainty_score":0.9996773},"labels":[],"label_agreement":null},{"id":"W4406311016","doi":"10.1093/g3journal/jkaf006","title":"A new <i>Drosophila melanogaster</i> research resource: CRISPR-induced mutations for clonal analysis of fourth chromosome genes","year":2025,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Human Genome Research Institute; National Institutes of Health; Ministry of Education, Culture, Sports, Science and Technology; National Science Foundation","keywords":"Biology; Drosophila melanogaster; Genetics; CRISPR; Gene; Drosophila (subgenus); Chromosome; Mutation; Computational biology; Evolutionary biology","score_opus":0.030391263412456224,"score_gpt":0.371660135405819,"score_spread":0.34126887199336275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406311016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46940193,0.38529363,0.14143011,0.0005812255,0.00049563544,0.001251161,0.000408916,0.000044361797,0.00109303],"genre_scores_gemma":[0.9397505,0.022788605,0.031575684,0.0002145929,0.0008701357,0.00019115038,0.0010052532,0.0000985631,0.003505526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975166,0.00010892208,0.0006210796,0.00072976906,0.0003791112,0.0006445329],"domain_scores_gemma":[0.99816465,0.00011202569,0.00012674394,0.0009416342,0.00045455643,0.0002003634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047955962,0.00032256293,0.00049586827,0.00072769064,0.00022359207,0.000057610596,0.0005915369,0.0002896099,0.000032674423],"category_scores_gemma":[0.00003055862,0.0003508169,0.00043341736,0.0014025022,0.00011189004,0.0000038405956,0.0003245013,0.00014318836,0.000004113324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089718844,0.000061542014,0.0029478362,0.000100177866,0.0014153352,0.0000017876188,0.00018479394,0.031373322,0.77004856,0.00015993205,0.0013505659,0.19226643],"study_design_scores_gemma":[0.0010333918,0.00048470558,0.0023933027,0.000022157623,0.0010096377,0.000005424111,0.00034254213,0.0039076325,0.6601368,0.00033707972,0.3299158,0.00041149856],"about_ca_topic_score_codex":0.000030382726,"about_ca_topic_score_gemma":0.00016254924,"teacher_disagreement_score":0.47034854,"about_ca_system_score_codex":0.00003961955,"about_ca_system_score_gemma":0.00042124063,"threshold_uncertainty_score":0.9998944},"labels":[],"label_agreement":null},{"id":"W4406503685","doi":"10.1016/s0765-2046(97)80013-5","title":"10.1016/s0765-2046(97)80013-5","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genetic enhancement; Medicine; Haemophilia B; Haemophilia A; Haemophilia; Biology; Gene; Genetics; Pediatrics","score_opus":0.003674340181600414,"score_gpt":0.20757386330305147,"score_spread":0.20389952312145104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406503685","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0044458006,0.000424668,0.0000538151,0.00008801891,0.0000026949788,0.00011609808,0.00001223841,0.000029574907,0.9948271],"genre_scores_gemma":[0.0021197218,0.0000023267305,0.00031282287,0.00004423937,0.0002546135,0.0000147835035,0.000047864756,0.000025704183,0.9971779],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932736,0.000011899574,0.000115637165,0.00023539692,0.00007990398,0.00022977433],"domain_scores_gemma":[0.99954176,0.000004414013,0.000010606229,0.0003013927,0.000024357163,0.00011746735],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00005974903,0.00012685102,0.00009661569,0.000026725816,0.00003709499,0.000017995577,0.00015422859,0.000083212,0.9615691],"category_scores_gemma":[0.000015813657,0.00013162242,0.00005910214,0.00007192995,0.000016154272,0.000001425956,0.00004392536,0.000051126346,0.9458821],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081754944,0.00004045231,4.2038855e-7,0.000009520722,0.000035932353,0.0000035494907,0.00000946024,0.0017466722,0.05276791,3.079372e-7,0.22735675,0.7179473],"study_design_scores_gemma":[0.00018228806,0.00016616612,0.000024285948,0.0000055427217,0.000009395414,0.000009860423,7.334626e-7,0.00010645336,0.03146233,0.000001392942,0.9678557,0.00017583476],"about_ca_topic_score_codex":0.0000063530965,"about_ca_topic_score_gemma":3.1067492e-7,"teacher_disagreement_score":0.74049896,"about_ca_system_score_codex":0.0000064800165,"about_ca_system_score_gemma":0.000015535657,"threshold_uncertainty_score":0.53674066},"labels":[],"label_agreement":null},{"id":"W4406519862","doi":"10.1016/s0765-2046(98)80087-7","title":"10.1016/s0765-2046(98)80087-7","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Alliance; Agriculture; Biology; Genetics; Political science; Ecology","score_opus":0.003450724958796996,"score_gpt":0.2080499342284277,"score_spread":0.2045992092696307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406519862","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0059644654,0.00034904317,0.000046304096,0.00009127732,0.0000026294856,0.000109003435,0.0000117551845,0.000029113808,0.9933964],"genre_scores_gemma":[0.0029265261,0.0000019672607,0.00031268783,0.000042685064,0.00025383788,0.000013694754,0.00004530648,0.00002518923,0.9963781],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993457,0.000011532591,0.00011217455,0.00022983362,0.00007863296,0.00022208675],"domain_scores_gemma":[0.9995544,0.000004203055,0.000010304492,0.00029414266,0.000023296634,0.00011366679],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00005783765,0.00012311839,0.00009771106,0.000026114252,0.00003587206,0.000017006498,0.0001505935,0.00008146806,0.96322566],"category_scores_gemma":[0.00001524133,0.00012790173,0.000058210553,0.00007071008,0.000015953377,0.0000013469804,0.000042738422,0.000050000657,0.9190394],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082022314,0.00004235967,4.515191e-7,0.000010188209,0.0000400957,0.0000039631163,0.000010531594,0.0017911241,0.063462846,3.4235157e-7,0.49588197,0.43867412],"study_design_scores_gemma":[0.00016953536,0.0001531831,0.000047175385,0.0000054684165,0.000009433416,0.000009586936,6.814592e-7,0.00010084108,0.029932456,0.0000013758481,0.969399,0.0001713027],"about_ca_topic_score_codex":0.000006984098,"about_ca_topic_score_gemma":3.191041e-7,"teacher_disagreement_score":0.473517,"about_ca_system_score_codex":0.0000063955395,"about_ca_system_score_gemma":0.000015755339,"threshold_uncertainty_score":0.5215681},"labels":[],"label_agreement":null},{"id":"W4406520755","doi":"10.1016/s0765-2046(97)89616-5","title":"10.1016/s0765-2046(97)89616-5","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Identification (biology); Computational biology; Gene; Cancer; Genetics; Biology; Ecology","score_opus":0.00364810016220818,"score_gpt":0.20754440760438045,"score_spread":0.20389630744217227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406520755","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0043689013,0.00039235814,0.000050805436,0.00008402416,0.0000026042205,0.0001257086,0.000012605647,0.000029982944,0.994933],"genre_scores_gemma":[0.0028509637,0.0000019708352,0.00023360587,0.000043953092,0.00026033033,0.000016147358,0.00004422755,0.000025674215,0.99652314],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993308,0.000011908165,0.00011549211,0.0002347428,0.000080183134,0.00022682745],"domain_scores_gemma":[0.99954265,0.000004407296,0.00001060751,0.00030167674,0.00002418876,0.00011645501],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00005840802,0.00012665623,0.00009612418,0.000026514062,0.000036989626,0.000017619412,0.00015369708,0.00008338853,0.96054995],"category_scores_gemma":[0.000016147507,0.00013143543,0.000059543247,0.00006923358,0.00001586611,0.0000014057479,0.00004326462,0.000051220126,0.94435513],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007135259,0.00003527634,3.573593e-7,0.000008451974,0.00003155508,0.000003156016,0.000008444418,0.0015792012,0.046494145,2.0657828e-7,0.18689877,0.7648691],"study_design_scores_gemma":[0.00018714565,0.00016831783,0.000019246785,0.000005632809,0.000009508528,0.000010012603,7.418396e-7,0.0001137915,0.03379094,0.0000010831133,0.9655182,0.00017537887],"about_ca_topic_score_codex":0.000005661357,"about_ca_topic_score_gemma":2.7892074e-7,"teacher_disagreement_score":0.7786194,"about_ca_system_score_codex":0.000006579045,"about_ca_system_score_gemma":0.000015904476,"threshold_uncertainty_score":0.53597814},"labels":[],"label_agreement":null},{"id":"W4406559961","doi":"10.1016/j.omtn.2025.102457","title":"Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group","year":2025,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Instituto de Salud Carlos III; Junta de Andalucía; Novo Nordisk Fonden; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja; European Research Council; Ministerio de Ciencia, Innovación y Universidades; Alexion Pharmaceuticals; Javna Agencija za Raziskovalno Dejavnost RS; Centre National de la Recherche Scientifique; Ministerio de Ciencia e Innovación; Novo Nordisk; H. Lundbeck A/S; Ikerbasque, Basque Foundation for Science; Lundbeckfonden; European Cooperation in Science and Technology; Innovationsfonden; Consejería de Salud y Consumo, Junta de Andalucía; Eusko Jaurlaritza","keywords":"Genome editing; Computational biology; Computer science; Gene delivery; Genome; Genetic enhancement; Biology; Action (physics); Gene; Genetics","score_opus":0.035202050850889934,"score_gpt":0.3437855952266771,"score_spread":0.30858354437578717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406559961","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027711652,0.953536,0.04072954,0.000047356003,0.0014069588,0.0036833573,0.00022664662,0.000050764404,0.000042298157],"genre_scores_gemma":[0.00018434804,0.9921805,0.0011924081,0.0009796929,0.0010886608,0.0013531181,0.0027680006,0.00015962654,0.000093609204],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99731696,0.00028787376,0.000726434,0.00091978523,0.00025647398,0.00049246807],"domain_scores_gemma":[0.9980706,0.00014346252,0.0003881923,0.0011428202,0.00015485415,0.000100097444],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025064638,0.0007353673,0.0012986144,0.000067902525,0.00021630764,0.0000947067,0.00075504807,0.00043394856,0.000009419012],"category_scores_gemma":[0.00006877185,0.0005838086,0.0009783437,0.00026616972,0.0000639856,0.0000049863547,0.0001928015,0.00034007442,0.000008039129],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043816322,0.0000361386,0.0000014725324,0.008171296,0.00092217437,0.000012321264,0.000012627813,0.0001956059,0.023892308,0.000011620481,0.0022234945,0.9644771],"study_design_scores_gemma":[0.0005838367,0.00012041448,0.0000023010873,0.013919512,0.00061213033,0.000032745498,0.00002751217,0.000040279785,0.0035341405,0.0000054793963,0.9805755,0.00054615736],"about_ca_topic_score_codex":0.000022290273,"about_ca_topic_score_gemma":0.0000034873453,"teacher_disagreement_score":0.978352,"about_ca_system_score_codex":0.00007867556,"about_ca_system_score_gemma":0.00013587362,"threshold_uncertainty_score":0.9996613},"labels":[],"label_agreement":null},{"id":"W4406599369","doi":"10.1101/2025.01.19.633652","title":"Gene syntax defines supercoiling-mediated transcriptional feedback","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; University of British Columbia Hospital","funders":"National Science Foundation Graduate Research Fellowship Program; Air Force Research Laboratory; Army Research Office; National Science Foundation; Canadian Institutes of Health Research; Novo Nordisk Fonden; Novo Nordisk; National Institute of General Medical Sciences; Institute for Collaborative Biotechnologies; Multidisciplinary University Research Initiative; Stem Cell Network; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Michael Smith Health Research BC; National Cancer Institute; National Institutes of Health","keywords":"DNA supercoil; Gene regulatory network; Chromatin; Biology; Gene; Computational biology; Regulation of gene expression; Enhancer; Transcription (linguistics); Gene expression; Genetics","score_opus":0.00880781966998766,"score_gpt":0.23579982578330574,"score_spread":0.22699200611331807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406599369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975187,0.008745823,0.012049375,0.00022256146,0.0018257102,0.00051188277,0.0012197748,0.00019679111,0.00004105994],"genre_scores_gemma":[0.98989904,0.0016305144,0.006987764,0.00029953424,0.0008436377,0.00017048788,0.00001638127,0.000098304445,0.000054359545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99750626,0.000068200585,0.000504263,0.0010865318,0.0002792091,0.0005555588],"domain_scores_gemma":[0.9981875,0.000025874286,0.000110280205,0.0010868765,0.00036000527,0.000229469],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002803094,0.0006144959,0.00046260536,0.00019139945,0.000118381045,0.000100464,0.0005699555,0.0008306484,0.000036547157],"category_scores_gemma":[0.0001895681,0.0007091263,0.0002838271,0.00025609764,0.0000971683,0.0000059097747,0.00038434064,0.0004947643,0.000034940524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035448513,0.00008066029,0.0019147425,0.00028866171,0.00022689371,0.000015986978,0.000004074724,0.00108148,0.9956319,0.00008695579,0.00063100253,0.0000022373154],"study_design_scores_gemma":[0.00057124725,0.000055401862,0.02656062,0.00019710389,0.00013325312,7.098364e-8,0.0000027018364,0.00024045559,0.95198864,0.0000011386245,0.019410733,0.0008386163],"about_ca_topic_score_codex":0.00003112295,"about_ca_topic_score_gemma":0.000008361954,"teacher_disagreement_score":0.0436432,"about_ca_system_score_codex":0.00007152199,"about_ca_system_score_gemma":0.00059604645,"threshold_uncertainty_score":0.999536},"labels":[],"label_agreement":null},{"id":"W4406608472","doi":"10.1590/1984-3143-ar2024-0037","title":"Swine clones: potential application for animal production and animal models","year":2025,"lang":"en","type":"review","venue":"Animal Reproduction","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal","funders":"Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Somatic cell nuclear transfer; Cloning (programming); Biology; Homologous recombination; Genetically modified organism; Somatic cell; Genetics; Recombinant DNA; Genome editing; Limiting; Molecular cloning; Gene; Computational biology; Biotechnology; CRISPR; Computer science; Blastocyst; Gene expression; Embryogenesis","score_opus":0.018246858927409387,"score_gpt":0.3444736834534987,"score_spread":0.3262268245260893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406608472","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018973314,0.97501373,0.020500734,0.00013409213,0.00045010037,0.0018410455,0.000043047068,0.000057313406,0.00006262547],"genre_scores_gemma":[0.020328576,0.9730266,0.0013129271,0.0000085699885,0.003262401,0.0005880238,0.0006935539,0.00006606834,0.00071330153],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99761575,0.00004155242,0.0004921196,0.0014489937,0.00012816861,0.00027339876],"domain_scores_gemma":[0.99892443,0.000008673346,0.00020456646,0.0006326616,0.00017020623,0.000059472535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036377038,0.0003825178,0.00057730096,0.00013695129,0.00014262568,0.000038287264,0.00013609111,0.0003787033,0.0000015993826],"category_scores_gemma":[0.00023924721,0.0003872238,0.0002522518,0.00019919807,0.00005066643,0.000014664273,0.000117866,0.00016049827,0.0000025640857],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005224355,0.00012785017,0.0000039359834,0.015514037,0.000258515,0.0000010610321,0.000025797459,0.00037268252,0.13131556,0.00036752518,0.0027639815,0.84872663],"study_design_scores_gemma":[0.0002470714,0.0010551983,0.000037047794,0.0010567657,0.0009747545,0.00022090983,0.000030639156,0.0005700113,0.013849252,0.00011164072,0.98113626,0.0007104396],"about_ca_topic_score_codex":0.000011978315,"about_ca_topic_score_gemma":0.0000056973895,"teacher_disagreement_score":0.9783723,"about_ca_system_score_codex":0.000034844365,"about_ca_system_score_gemma":0.0001387039,"threshold_uncertainty_score":0.99985796},"labels":[],"label_agreement":null},{"id":"W4406708239","doi":"10.1021/acs.analchem.4c05304","title":"Quantitative Analysis of Phosphorothioate Isomers in CRISPR sgRNA at Single-Residue Resolution Using Endonuclease Digestion Coupled with Liquid Chromatography Cyclic Ion Mobility Mass Spectrometry (LC/cIMS)","year":2025,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nexen (Canada)","funders":"","keywords":"Chemistry; Chromatography; Mass spectrometry; Endonuclease; Ion-mobility spectrometry; Residue (chemistry); Liquid chromatography–mass spectrometry; Ion; Resolution (logic); Analytical Chemistry (journal); Enzyme; Biochemistry; Organic chemistry","score_opus":0.009661670881032541,"score_gpt":0.29163154922946277,"score_spread":0.28196987834843024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406708239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96559745,0.00087967335,0.032725386,0.000047373236,0.000022616348,0.0001374088,0.000026306638,0.000016900392,0.00054687675],"genre_scores_gemma":[0.9981771,0.00010769638,0.0014267733,0.000025561067,0.000022089045,0.000009408044,0.00014932067,0.000018046594,0.0000639934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984008,0.00003899296,0.0004460552,0.000561274,0.00021756518,0.0003353141],"domain_scores_gemma":[0.9991442,0.000055037992,0.00012652444,0.0004558975,0.000112917696,0.00010544559],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021873794,0.0002459839,0.00043001794,0.00025494135,0.000059924496,0.000017446455,0.00015708488,0.00022184908,0.000042697604],"category_scores_gemma":[0.00017232246,0.0002478316,0.00024841633,0.0016176242,0.00020921984,0.000007997317,0.00008509498,0.00016543346,6.268226e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090355746,0.00018658036,0.014591292,0.00013508828,0.0006793855,0.000008059196,0.000020304575,0.028759679,0.9546581,0.000031927782,0.000015099442,0.000010942212],"study_design_scores_gemma":[0.00057972525,0.00021640085,0.013820435,0.000078342906,0.00073642266,0.000002867125,0.0001413111,0.08795479,0.8961935,0.000015398256,0.000023225495,0.00023757044],"about_ca_topic_score_codex":0.00022783445,"about_ca_topic_score_gemma":0.000115264374,"teacher_disagreement_score":0.05919511,"about_ca_system_score_codex":0.00015023393,"about_ca_system_score_gemma":0.00006489576,"threshold_uncertainty_score":0.9999974},"labels":[],"label_agreement":null},{"id":"W4406795004","doi":"10.1073/pnas.2425178122","title":"Evidence that ARK2N is not a core factor in transcription-coupled DNA repair","year":2025,"lang":"en","type":"letter","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Aard- en Levenswetenschappen, Nederlandse Organisatie voor Wetenschappelijk Onderzoek; European Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Core (optical fiber); DNA; Transcription factor; DNA repair; Computational biology; Genetics; Biology; Computer science; Gene; Telecommunications","score_opus":0.07138522085816855,"score_gpt":0.3442540818680248,"score_spread":0.27286886100985625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406795004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7396587,0.0024593307,0.000022229138,0.2557835,0.00014766527,0.00060362933,0.00015735006,0.000019938654,0.0011476325],"genre_scores_gemma":[0.9469259,0.00046419358,0.00047496564,0.05064514,0.0003211586,0.000022220664,0.0000017513153,0.000007330598,0.0011373529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982765,0.0000044867993,0.0003141544,0.000411338,0.0008096292,0.00018392087],"domain_scores_gemma":[0.9994618,0.00005893369,0.0002788391,0.000019361489,0.00016405538,0.000016989794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046821116,0.00016373218,0.00020530589,0.00017750023,0.000061326165,0.000016380656,0.00082285434,0.00040632996,0.000015090561],"category_scores_gemma":[0.0004489736,0.00012438673,0.00019166093,0.00036050903,0.00030755103,0.000016625487,0.000112434005,0.0004039033,3.7158154e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016609914,0.0000109918465,0.002275553,0.00038647602,0.000029542029,3.085761e-8,0.000098533405,0.000043725573,0.88954824,0.00007725824,0.10741169,0.00010134944],"study_design_scores_gemma":[0.00017552853,0.00006306617,0.021684768,0.00087629055,0.00002750271,0.0000063461725,0.000044382305,0.0007940718,0.94756013,0.00088881893,0.02765402,0.0002250856],"about_ca_topic_score_codex":0.000009041287,"about_ca_topic_score_gemma":2.914703e-7,"teacher_disagreement_score":0.20726717,"about_ca_system_score_codex":0.000023717788,"about_ca_system_score_gemma":0.00007400682,"threshold_uncertainty_score":0.50723433},"labels":[],"label_agreement":null},{"id":"W4406904432","doi":"10.1101/2025.01.26.633040","title":"A highly efficient CRISPR-Cas9-based gene editing system in oat ( <i>Avena sativa</i> )","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Avena; CRISPR; Genome editing; Gene; Cas9; Biology; Computational biology; Genetics; Biotechnology; Agronomy","score_opus":0.006299060536411113,"score_gpt":0.23312470605029978,"score_spread":0.22682564551388867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406904432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9309242,0.0042616967,0.06021323,0.00011714374,0.002620013,0.0010571447,0.00047587432,0.00026155432,0.00006916346],"genre_scores_gemma":[0.99249303,0.00007630059,0.0058815377,0.00016662624,0.00096254214,0.00029628453,0.0000044475473,0.000108867265,0.000010337711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966727,0.00014368813,0.00073766086,0.0013375944,0.00035576167,0.0007526061],"domain_scores_gemma":[0.9976877,0.000039147213,0.0002788645,0.0014604606,0.0003073595,0.0002264862],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062845903,0.00070484006,0.0006341065,0.00035144048,0.00011713274,0.00012029516,0.0006243189,0.0007701255,0.0000050015287],"category_scores_gemma":[0.00019369442,0.00081084965,0.00025426236,0.00044170374,0.00007251262,0.000003591938,0.00062546507,0.0006259519,0.000014059387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004239212,0.000119894314,0.0018691701,0.0012377109,0.00009969514,0.00006135438,0.0000087278795,0.042291094,0.95381904,0.000085109205,0.0003622284,0.0000035713786],"study_design_scores_gemma":[0.00089291064,0.00005846309,0.0050856937,0.001063493,0.00008547586,4.699712e-8,0.000011164566,0.010149824,0.97713333,1.4223181e-7,0.0047135297,0.0008059442],"about_ca_topic_score_codex":0.000080692414,"about_ca_topic_score_gemma":0.000008890186,"teacher_disagreement_score":0.06156888,"about_ca_system_score_codex":0.00028632281,"about_ca_system_score_gemma":0.00067743514,"threshold_uncertainty_score":0.99943423},"labels":[],"label_agreement":null},{"id":"W4406993196","doi":"10.1186/s13073-025-01428-6","title":"Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone","year":2025,"lang":"en","type":"article","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases","keywords":"CRISPR; Klebsiella pneumoniae; Biology; Drug resistance; Computational biology; Gene; clone (Java method); Human genetics; Antimicrobial; Multi drug resistant; Antibiotic resistance; Antimicrobial drug; Genetics; Microbiology; Escherichia coli; Bacteria","score_opus":0.00516529554435117,"score_gpt":0.2874739684190762,"score_spread":0.282308672874725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406993196","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89828485,0.0661703,0.032591175,0.0012737302,0.0003960055,0.00081784074,0.00006995362,0.000023424629,0.00037270592],"genre_scores_gemma":[0.9933688,0.0042436253,0.0009725655,0.00011786986,0.00014444253,0.000033367683,0.000058196132,0.000025079189,0.0010360621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981381,0.00008782813,0.0006768498,0.0005538443,0.00017322037,0.00037009857],"domain_scores_gemma":[0.9991076,0.000024531751,0.00015310541,0.0004818481,0.00014023687,0.00009269282],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050014583,0.00028411616,0.0005412983,0.00024495565,0.000056406545,0.000021332477,0.00034435684,0.00014199404,0.000004824878],"category_scores_gemma":[0.0001300155,0.0002559492,0.0000506856,0.00039118496,0.00020230794,0.000006033924,0.00022961223,0.00014970289,0.0000011816932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002128701,0.00006917269,0.0067530526,0.0009347638,0.0000758415,0.00003337944,0.00022378596,0.00027641177,0.99017596,0.00005863676,0.00087801344,0.00030813826],"study_design_scores_gemma":[0.0070858933,0.0005045364,0.07541301,0.0024115306,0.00020748637,0.000065875465,0.001302711,0.00069864356,0.8460817,0.000035394263,0.06522553,0.00096770463],"about_ca_topic_score_codex":0.00047033746,"about_ca_topic_score_gemma":0.0006476624,"teacher_disagreement_score":0.14409424,"about_ca_system_score_codex":0.00004309373,"about_ca_system_score_gemma":0.000088885536,"threshold_uncertainty_score":0.9999893},"labels":[],"label_agreement":null},{"id":"W4406995463","doi":"10.1038/s41467-025-56282-2","title":"Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"Australian Government; National Health and Medical Research Council; Austin Medical Research Foundation","keywords":"CRISPR; Genome editing; Genome engineering; Biology; Computational biology; Gene knockout; Gene knockin; Gene; Recombineering; Synthetic biology; mCherry; Reporter gene; Gene targeting; Cell biology; Molecular biology; Genome; Genetics; Green fluorescent protein; Gene expression","score_opus":0.004075225082337047,"score_gpt":0.28241781021783346,"score_spread":0.2783425851354964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406995463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6437689,0.19316113,0.14252014,0.007824762,0.00039262755,0.00088694674,0.000045849716,0.00013045607,0.011269158],"genre_scores_gemma":[0.98782843,0.00064230844,0.010885045,0.00032696992,0.000026070667,0.00002332119,0.00010100974,0.00002008459,0.00014673079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992478,0.000052697535,0.00018121858,0.00020451128,0.00008109939,0.00023268463],"domain_scores_gemma":[0.9987364,0.00012418663,0.000037653183,0.000999237,0.00006456138,0.000038006794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015073018,0.00014770922,0.00012690232,0.00005802113,0.0001517176,0.00004128263,0.00065596576,0.00016119912,0.000002016064],"category_scores_gemma":[0.00013845414,0.00012579255,0.000049145052,0.00032640298,0.000042931773,0.000004719324,0.00007131372,0.0005818489,5.6288684e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021404972,0.00007778208,0.0145328175,0.000029507675,0.0001269133,0.0000018535025,0.00015993355,0.041556474,0.9355317,0.0003873879,0.0049451496,0.0026290964],"study_design_scores_gemma":[0.001616946,0.00011890854,0.07593722,0.00048840384,0.00011219059,0.000067584406,0.0010416684,0.015112953,0.5404791,0.000015955105,0.36425886,0.0007501761],"about_ca_topic_score_codex":0.0000305587,"about_ca_topic_score_gemma":0.00036070982,"teacher_disagreement_score":0.39505252,"about_ca_system_score_codex":0.000020520285,"about_ca_system_score_gemma":0.00005045007,"threshold_uncertainty_score":0.5129671},"labels":[],"label_agreement":null},{"id":"W4407083815","doi":"10.1021/acssynbio.4c00569","title":"Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells","year":2025,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Global Health Research","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of Allergy and Infectious Diseases; National Institute on Aging; Consejo Nacional de Ciencia y Tecnología; American Association of Immunologists; National Science Foundation Graduate Research Fellowship Program; National Institute of General Medical Sciences; Dunn Foundation; American Heart Association; Fulbright Program","keywords":"Biology; DNA methylation; Methyltransferase; Epigenetics; DNA methyltransferase; Methylation; Gene silencing; Genetics; Epigenome; Epigenomics; Computational biology; Gene; Gene expression","score_opus":0.00598384813080284,"score_gpt":0.2676104696603606,"score_spread":0.2616266215295578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407083815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9155106,0.0005136182,0.08352957,0.000064646585,0.000033040167,0.00022285941,0.000048916525,0.000009828476,0.00006691072],"genre_scores_gemma":[0.9985355,0.00015418894,0.00086378225,0.00009556019,0.000025770976,0.000036730264,0.00023029737,0.0000170643,0.000041073446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990324,0.000115939314,0.00026951332,0.0003534827,0.00005011681,0.00017856238],"domain_scores_gemma":[0.99961615,0.00007798276,0.00004887185,0.00017706504,0.000043607033,0.00003632082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018033253,0.00019395498,0.00027719856,0.00013950621,0.00007891689,0.000012994105,0.000085397915,0.00015392524,0.000005533347],"category_scores_gemma":[0.000015800604,0.00017521477,0.0000308095,0.00009006018,0.000199049,0.000005751223,0.000028862012,0.000074724136,5.120772e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008021448,0.00007215542,0.003243185,0.00018488673,0.000025234078,0.0000015440927,0.000082849816,0.000090492686,0.9954626,0.000071870905,0.0000012705124,0.00068369944],"study_design_scores_gemma":[0.0007057257,0.0003712783,0.012705902,0.00005406496,0.000053068557,0.000002912919,0.00003874065,0.000032776396,0.98576677,0.000037260084,0.0000545213,0.00017695653],"about_ca_topic_score_codex":0.000041999756,"about_ca_topic_score_gemma":0.00008887872,"teacher_disagreement_score":0.08302493,"about_ca_system_score_codex":0.00000938735,"about_ca_system_score_gemma":0.00006357038,"threshold_uncertainty_score":0.7145051},"labels":[],"label_agreement":null},{"id":"W4407086288","doi":"10.1080/07366205.2025.2457889","title":"CRISPR screens in neurological research: exploring the functional basis of aging and disease","year":2025,"lang":"en","type":"article","venue":"BioTechniques","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"CRISPR; Disease; Biology; Neuroscience; Computational biology; Genetics; Medicine; Gene; Pathology","score_opus":0.06961229021355922,"score_gpt":0.3687851723747715,"score_spread":0.2991728821612123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407086288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97138786,0.0018897171,0.024444982,0.001797922,0.000043768643,0.00015173903,0.000004815327,0.000019498471,0.00025969514],"genre_scores_gemma":[0.9981614,0.0008087866,0.00075175153,0.00013029801,0.000041441926,0.000043303196,0.0000040620243,0.000004548075,0.00005441604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947804,0.000058333342,0.000099331395,0.000167905,0.000074552714,0.00012183413],"domain_scores_gemma":[0.99971265,0.00003632811,0.00000945063,0.00017389265,0.00003328263,0.00003440562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033952392,0.00005668741,0.000057469795,0.00008629269,0.000045237168,0.000008882371,0.00008658676,0.00004853433,0.0000021478697],"category_scores_gemma":[0.00020523168,0.00004326886,0.000026672671,0.00013099576,0.000095672054,0.00000195989,0.00016183667,0.00012248234,1.1413743e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021515007,0.000092196045,0.09275546,0.000129816,0.000030130306,0.000010172381,0.00006383763,0.00022829816,0.8626406,0.004696376,0.0055836774,0.033554252],"study_design_scores_gemma":[0.00010597043,0.0000824808,0.3287043,0.000047630434,0.000006007066,0.0000013054859,0.00005055378,0.00022015595,0.65812385,0.00076506304,0.011819635,0.00007303681],"about_ca_topic_score_codex":0.000030713414,"about_ca_topic_score_gemma":0.000013838737,"teacher_disagreement_score":0.23594885,"about_ca_system_score_codex":0.0000027904412,"about_ca_system_score_gemma":0.000026061145,"threshold_uncertainty_score":0.17644529},"labels":[],"label_agreement":null},{"id":"W4407107404","doi":"10.3390/genes16020185","title":"Integrating Machine Learning-Based Approaches into the Design of ASO Therapies","year":2025,"lang":"en","type":"review","venue":"Genes","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canadian Institutes of Health Research; Muscular Dystrophy Canada; University of Alberta; Alberta Innovates - Health Solutions; Women and Children's Health Research Institute; Children's Health Research Institute; Alberta Innovates; Heart and Stroke Foundation of Canada; U.S. Department of Defense","keywords":"Generalizability theory; Computer science; Machine learning; Clinical trial; Medicine; Exon skipping; Risk analysis (engineering); Artificial intelligence; Bioinformatics; Biology; RNA","score_opus":0.03778373683802093,"score_gpt":0.32309823573999313,"score_spread":0.2853144989019722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407107404","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000008235661,0.86953753,0.12994753,0.000015916261,0.00008654253,0.00030753328,0.000006887559,0.00001124307,0.000078554694],"genre_scores_gemma":[0.00043033762,0.99389076,0.0047374265,0.000014315149,0.00012423216,0.000107939275,0.00017258443,0.000032065305,0.00049035595],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989836,0.00021720005,0.00029245947,0.0002739408,0.000084934385,0.00014781907],"domain_scores_gemma":[0.9993269,0.00011728681,0.00013670331,0.0003633545,0.000034542398,0.000021228081],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031873054,0.00028110278,0.00050062255,0.000064040905,0.000078403966,0.000019440331,0.00034704973,0.00020331575,0.000007059595],"category_scores_gemma":[0.00012158371,0.00017221167,0.0002780956,0.00013782055,0.00006515926,6.3699173e-7,0.00010084599,0.00017739987,0.0000013626948],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005190993,0.000013443781,0.000008926303,0.004096527,0.00017813938,3.4795056e-7,0.00008417031,0.0053574136,0.0006733453,0.000015698466,0.00006301501,0.9895038],"study_design_scores_gemma":[0.00008254346,0.000107245214,9.664054e-7,0.0012781835,0.00023082999,0.000002877165,0.00007937514,0.0010612286,0.00567997,0.000010311289,0.9912383,0.00022814905],"about_ca_topic_score_codex":0.000019851645,"about_ca_topic_score_gemma":0.000017655191,"teacher_disagreement_score":0.9911753,"about_ca_system_score_codex":0.0000076170068,"about_ca_system_score_gemma":0.00018420634,"threshold_uncertainty_score":0.7022588},"labels":[],"label_agreement":null},{"id":"W4407394575","doi":"10.1126/scitranslmed.adk3920","title":"In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene","year":2025,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Transgene; Carcinogenesis; Biology; DNA repair; Gene; Genome editing; Gene targeting; Somatic cell; Cell biology; Genetically modified mouse; Genetic enhancement; In vivo; Cancer research; Genetics; Genome","score_opus":0.008489328931612767,"score_gpt":0.3171436070033842,"score_spread":0.3086542780717714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407394575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.923414,0.0007300139,0.074966796,0.00032087442,0.00015553937,0.00012712358,0.000014562955,0.0000030880888,0.0002680288],"genre_scores_gemma":[0.9952059,0.00006707815,0.0045487676,0.00006024612,0.000057715708,0.000005480848,0.00003743291,0.0000036228541,0.000013805594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909616,0.000016209968,0.000279349,0.00022134931,0.00026589472,0.00012103981],"domain_scores_gemma":[0.9996754,0.00001030222,0.000036684436,0.00013771701,0.00010852395,0.00003140451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026894844,0.000076801596,0.00012695546,0.00013286182,0.000030952993,0.0000017211205,0.000101740465,0.00004112683,0.0000353539],"category_scores_gemma":[0.000028690403,0.00006897361,0.0000287324,0.00039796895,0.00034738955,0.000014369193,0.0000072112425,0.000036011214,1.006703e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053409076,0.00003644679,0.00033420237,0.000029025741,0.0000044571957,7.073016e-7,0.00044464643,0.004750489,0.9937099,0.0002862861,0.000014202329,0.0003362245],"study_design_scores_gemma":[0.0007667646,0.00014502568,0.008338215,0.000059084432,0.00001032606,0.0000023755974,0.00009385234,0.0020365557,0.9880016,0.00039117615,0.0000971961,0.00005784308],"about_ca_topic_score_codex":0.0000665547,"about_ca_topic_score_gemma":0.00003646386,"teacher_disagreement_score":0.07179188,"about_ca_system_score_codex":0.0000061050164,"about_ca_system_score_gemma":0.00015049223,"threshold_uncertainty_score":0.2812662},"labels":[],"label_agreement":null},{"id":"W4407395709","doi":"10.1101/2025.02.10.25321921","title":"Screening rare genetic diagnoses for amenability to bespoke antisense oligonucleotide therapy development: a retrospective cohort study","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"Bespoke; Medical diagnosis; Cohort; Retrospective cohort study; Oligonucleotide; Medicine; Internal medicine; Genetics; Business; Biology; Pathology; DNA","score_opus":0.015567258530522252,"score_gpt":0.32376303885869373,"score_spread":0.30819578032817146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407395709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9458338,0.001191231,0.048500773,0.000055412587,0.0004740651,0.0036778522,0.000116846815,0.000056209017,0.00009383532],"genre_scores_gemma":[0.9815886,0.0003050154,0.015662735,0.0001442638,0.00027594122,0.0014194903,0.00013111204,0.000057553716,0.00041528777],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9974421,0.00009152574,0.0004903584,0.0012914175,0.00024604666,0.00043854341],"domain_scores_gemma":[0.99843496,0.000048655525,0.00010603226,0.0010087825,0.00024981864,0.00015177035],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052836485,0.00047681236,0.0005550959,0.00013713122,0.00015163909,0.000067592766,0.00047428728,0.00025328994,0.000012748882],"category_scores_gemma":[0.00036971818,0.0004931375,0.0002028024,0.00014673418,0.000039179446,0.0000017450373,0.00072812865,0.00023613275,0.000002402024],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016105572,0.00022600613,0.97303766,0.000111208625,0.0005074116,0.000009211949,0.0005454266,0.0034815015,0.014297742,0.0000014453796,0.00034401048,0.0072773295],"study_design_scores_gemma":[0.0006187994,0.00029954113,0.8767833,0.00008259891,0.00005848509,0.0000017604874,0.00010946409,0.000078455,0.11449681,0.000022382472,0.0069595156,0.0004888484],"about_ca_topic_score_codex":0.00006317643,"about_ca_topic_score_gemma":0.00019125502,"teacher_disagreement_score":0.100199066,"about_ca_system_score_codex":0.000063272455,"about_ca_system_score_gemma":0.0001862918,"threshold_uncertainty_score":0.99975204},"labels":[],"label_agreement":null},{"id":"W4407396825","doi":"10.1038/s41467-025-56734-9","title":"EXPERT expands prime editing efficiency and range of large fragment edits","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Institute of Hydrobiology; Foundation for Innovative Research Groups of the National Natural Science Foundation of China; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Fragment (logic); Computer science; Upstream (networking); Prime (order theory); Range (aeronautics); Knowledge base; Base (topology); Downstream (manufacturing); Computational biology; Indel; Genome editing; Biology; Artificial intelligence; Genetics; Programming language; Genome; Mathematics; Combinatorics; Engineering; Telecommunications","score_opus":0.005999410287394852,"score_gpt":0.3362557704391661,"score_spread":0.33025636015177123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407396825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5550389,0.3519008,0.06889672,0.0050739874,0.0012777612,0.00068360067,0.000104388215,0.000066323446,0.01695753],"genre_scores_gemma":[0.9952391,0.0016975984,0.0025715476,0.00019504651,0.00008663832,0.000019905361,0.00005170697,0.000005463293,0.00013304135],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99959695,0.000022535578,0.000118837415,0.000111664995,0.00005286545,0.00009713717],"domain_scores_gemma":[0.99920726,0.000026957958,0.000029649622,0.00064810365,0.00006545507,0.000022560926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012081903,0.000065548265,0.000075956785,0.000039645915,0.00008950964,0.0000065865866,0.0002871906,0.00014924754,0.0000026580879],"category_scores_gemma":[0.00010500101,0.000064751664,0.000031261032,0.00009390618,0.000043989054,0.000001559431,0.00031216038,0.00016423865,2.8443705e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030435634,0.00051486143,0.01939449,0.000099073724,0.00016527293,4.8059957e-7,0.00097453577,0.000084104875,0.9343368,0.008381946,0.025219208,0.010798779],"study_design_scores_gemma":[0.0013213493,0.00010834642,0.026578303,0.00014436728,0.000043548753,0.000004346606,0.0007225151,0.0017452015,0.4338927,0.0000630976,0.53509283,0.0002833984],"about_ca_topic_score_codex":0.0000033097876,"about_ca_topic_score_gemma":0.000028820963,"teacher_disagreement_score":0.5098736,"about_ca_system_score_codex":0.000005092894,"about_ca_system_score_gemma":0.000023529272,"threshold_uncertainty_score":0.26404962},"labels":[],"label_agreement":null},{"id":"W4407557225","doi":"10.5376/bm.2024.15.0031","title":"Application of CRISPR/Cas9 in Wheat Genetic Improvement","year":2024,"lang":"en","type":"article","venue":"Bioscience Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Biology; Genetics; Genome editing; Computational biology; Gene","score_opus":0.011850764539833011,"score_gpt":0.4076862057434908,"score_spread":0.39583544120365777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407557225","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16977145,0.0026254442,0.8269681,0.00006427961,0.00024456962,0.00012354943,0.0000029943662,0.000009588484,0.0001900516],"genre_scores_gemma":[0.8568387,0.00014858742,0.14276312,0.000033713077,0.000056586192,0.000029152687,0.000002823162,0.000008017124,0.000119280274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925876,0.00003467689,0.00017173163,0.00029767194,0.00008484737,0.0001523224],"domain_scores_gemma":[0.9996794,0.000014961268,0.000017198077,0.00023177471,0.000019523019,0.00003715898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004920924,0.00007837244,0.00007954651,0.00007845965,0.000014885838,0.000014765297,0.00015331522,0.000056768447,0.0000048291763],"category_scores_gemma":[0.000048295788,0.000071411196,0.00004100452,0.00026289272,0.000055834254,0.000002270111,0.00006895422,0.00004157413,0.0000021161036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000018555717,0.000010041992,0.00031717576,0.000032199463,0.0000021128778,4.3878464e-7,0.000029941952,0.00027996465,0.8001297,0.00009073264,0.000032305994,0.19907351],"study_design_scores_gemma":[0.000056798035,0.0001091837,0.0071711624,0.000012263401,0.0000046550504,0.00000366795,0.000038029866,0.011066681,0.96630293,0.00011831807,0.015029242,0.00008708493],"about_ca_topic_score_codex":0.000032934764,"about_ca_topic_score_gemma":0.000009870822,"teacher_disagreement_score":0.6870673,"about_ca_system_score_codex":0.000012267535,"about_ca_system_score_gemma":0.00004486298,"threshold_uncertainty_score":0.2912064},"labels":[],"label_agreement":null},{"id":"W4407605602","doi":"10.1101/2025.02.12.637884","title":"A functional map of phosphoprotein phosphatase regulation identifies an evolutionary conserved reductase for the catalytic metal ions","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Phosphatase; Conserved sequence; Phosphoprotein; Biology; Activator (genetics); Cell biology; Kinase; Function (biology); Allosteric regulation; Biochemistry; Serine; Derepression; Intracellular; Phosphorylation; Enzyme; Gene; Peptide sequence; Gene expression; Psychological repression","score_opus":0.012734620064815357,"score_gpt":0.25155757504592774,"score_spread":0.2388229549811124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407605602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8364867,0.0422467,0.10608502,0.0007544376,0.0038498994,0.0033117272,0.007114577,0.0001468456,0.000004121697],"genre_scores_gemma":[0.99458486,0.00013489618,0.0040872507,0.0000495806,0.00038227582,0.0005563173,0.000068766545,0.000043885553,0.000092178525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835825,0.00005426484,0.0004425063,0.0006645155,0.00020916775,0.00027131004],"domain_scores_gemma":[0.997949,0.00004975683,0.00023461207,0.0011617063,0.0005049503,0.00009996777],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040932375,0.0003312988,0.00028831032,0.00010255953,0.00018795038,0.0000501316,0.00037000596,0.0003306461,0.000028160619],"category_scores_gemma":[0.00020983357,0.0003214264,0.00022799874,0.00014857478,0.0001651152,0.000011087271,0.00030664058,0.00020567531,0.0000035682212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016569208,0.000115293995,0.00019983057,0.00043030802,0.00036570313,0.0000014952878,0.000004788514,0.0048436075,0.9889386,0.00051286747,0.0044179726,0.0000037858404],"study_design_scores_gemma":[0.00048606517,0.00006607697,0.015632898,0.00011663763,0.00029835978,4.1926207e-8,0.000009274724,0.0021940405,0.9757507,0.000012120566,0.0050942707,0.0003395064],"about_ca_topic_score_codex":0.00009781831,"about_ca_topic_score_gemma":0.000009245016,"teacher_disagreement_score":0.15809818,"about_ca_system_score_codex":0.000054050608,"about_ca_system_score_gemma":0.0006103459,"threshold_uncertainty_score":0.99992377},"labels":[],"label_agreement":null},{"id":"W4407633387","doi":"10.1007/s00299-025-03450-9","title":"Prime editing via precise sequence insertion restores function of the recessive rc allele in rice","year":2025,"lang":"en","type":"article","venue":"Plant Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Vietnam Academy of Science and Technology","keywords":"Biology; Allele; Genetics; Loss function; Sequence (biology); Plant biochemistry; Function (biology); Gene; Phenotype","score_opus":0.006459401865590555,"score_gpt":0.25033453151036505,"score_spread":0.2438751296447745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407633387","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99272597,0.0007011859,0.0038029265,0.000029885883,0.00044554187,0.00013991554,0.0000031690706,0.0000063636467,0.0021450333],"genre_scores_gemma":[0.9991002,0.000070216425,0.000099798875,0.000018678791,0.0000664015,0.000012479442,0.00005403964,0.0000050231374,0.0005731646],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937326,0.000023961542,0.00022934124,0.00018763213,0.000084094594,0.000101691665],"domain_scores_gemma":[0.99958044,0.000009979162,0.00012641221,0.00023142755,0.000036129688,0.000015581687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015737479,0.00007036039,0.00007536801,0.000033170745,0.000028899742,0.000005065456,0.000060151546,0.00007532894,0.0000033304996],"category_scores_gemma":[0.000100871315,0.000057900364,0.00003313972,0.00009776533,0.00001695219,0.0000025626482,0.00005656834,0.00006841186,2.737553e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028750226,0.000023045466,0.013928101,0.000045881236,0.000007278701,0.0000111210775,0.000029126084,0.0015831601,0.982745,0.0000016038093,0.00068546017,0.0009114816],"study_design_scores_gemma":[0.00008474431,0.000028491186,0.04182907,0.00005599426,0.000012078114,0.00002527034,0.000025617828,0.0002817564,0.95246583,0.000059951104,0.0050695073,0.00006169882],"about_ca_topic_score_codex":0.000085336294,"about_ca_topic_score_gemma":0.00010903428,"teacher_disagreement_score":0.030279169,"about_ca_system_score_codex":0.000014780773,"about_ca_system_score_gemma":0.000050952563,"threshold_uncertainty_score":0.23611084},"labels":[],"label_agreement":null},{"id":"W4407679695","doi":"10.1089/hum.2024.170","title":"Minimally Humanized <i>Ezh2</i> Exon-18 Mouse Cell Lines Validate Preclinical CRISPR/Cas9 Approach to Treat Weaver Syndrome","year":2025,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"CRISPR; Humanized mouse; Exon; Cas9; Gene knockin; Genome editing; Biology; Cancer research; Medicine; Genetics; Gene","score_opus":0.031303325612194385,"score_gpt":0.3465706260901964,"score_spread":0.315267300478002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407679695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812298,0.002651698,0.008731747,0.000072107876,0.00018074688,0.00057326775,0.000027414915,0.00007682332,0.0064564194],"genre_scores_gemma":[0.9713146,0.0007516653,0.0046231784,0.00098673,0.00031971253,0.00013088092,0.00020941133,0.00008206206,0.021581756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807143,0.00008572486,0.000459425,0.0007642227,0.00016825576,0.00045094173],"domain_scores_gemma":[0.9987962,0.000019483874,0.00006604648,0.0008663506,0.00009410912,0.00015775766],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024302218,0.00038836998,0.0003938389,0.00012042105,0.00016572348,0.00007603945,0.0004951628,0.0002492476,0.000085277556],"category_scores_gemma":[0.000016902643,0.00037079214,0.00023432725,0.00015861378,0.000062074134,0.000004693616,0.00017120963,0.00015131258,0.000032798867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021405327,0.00035763884,0.0002165439,0.000049149206,0.00009149463,0.000007415413,0.00012793628,0.0005385014,0.9881379,0.000023308716,0.009467209,0.0007688345],"study_design_scores_gemma":[0.0022977216,0.00065009604,0.0011739199,0.000013745361,0.00004035716,0.000017950644,0.00004520182,0.00005339229,0.9665137,0.00004217412,0.028706616,0.0004451593],"about_ca_topic_score_codex":0.00001737797,"about_ca_topic_score_gemma":0.000007612969,"teacher_disagreement_score":0.021624248,"about_ca_system_score_codex":0.000019707088,"about_ca_system_score_gemma":0.000056288874,"threshold_uncertainty_score":0.9998744},"labels":[],"label_agreement":null},{"id":"W4407711433","doi":"10.3390/ijms26041723","title":"Risk Prediction of RNA Off-Targets of CRISPR Base Editors in Tissue-Specific Transcriptomes Using Language Models","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Co-creation place formation support program; Institute of Genetics; Japan Science and Technology Agency","keywords":"Transcriptome; RNA; CRISPR; Computational biology; Computer science; Pipeline (software); RNA-Seq; Biology; Gene; Gene expression; Bioinformatics; Genetics","score_opus":0.010288584500660083,"score_gpt":0.3130991266301186,"score_spread":0.3028105421294585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407711433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73930603,0.0070317225,0.25234288,0.000055653363,0.0010327878,0.000035928424,0.000020498155,0.0000010554323,0.00017339973],"genre_scores_gemma":[0.99359584,0.0006654876,0.0055261464,0.000014928122,0.00018273269,5.960473e-7,0.000002698139,0.0000039229835,0.000007669131],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904263,0.00003797359,0.00038014702,0.00011853531,0.00033298874,0.00008773735],"domain_scores_gemma":[0.999483,0.00001338501,0.00018642149,0.00007784343,0.00021387158,0.000025489237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039869384,0.00007133432,0.00012372337,0.00028750964,0.00001587117,0.000012292897,0.0003243361,0.000049956787,0.000006984708],"category_scores_gemma":[0.00006012078,0.00006552923,0.000088194014,0.00015470768,0.00009262896,0.00001580563,0.000034603578,0.00007120351,6.899377e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034003548,0.000042878066,0.0009795387,0.000007856698,0.00004374186,0.0000093401795,0.00014888408,0.11183104,0.88309205,0.000055352095,0.00009905592,0.0036562432],"study_design_scores_gemma":[0.00040266186,0.00013128722,0.0011679329,0.000082991406,0.000013979636,0.000012278723,0.00029524177,0.008170293,0.9888551,0.00029054648,0.0005284336,0.00004924278],"about_ca_topic_score_codex":0.00003314704,"about_ca_topic_score_gemma":0.000005537686,"teacher_disagreement_score":0.25428975,"about_ca_system_score_codex":0.000015787778,"about_ca_system_score_gemma":0.00009049423,"threshold_uncertainty_score":0.26722047},"labels":[],"label_agreement":null},{"id":"W4407876100","doi":"10.1186/s13073-025-01436-6","title":"Correction: Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone","year":2025,"lang":"en","type":"erratum","venue":"Genome Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Klebsiella pneumoniae; Computational biology; Biology; clone (Java method); Gene; Drug resistance; Human genetics; Antimicrobial; Genetics; Microbiology; Escherichia coli","score_opus":0.005427191960173876,"score_gpt":0.27961353031249203,"score_spread":0.27418633835231815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407876100","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.064588726,0.7865657,0.0653311,0.0037459193,0.06140806,0.005873283,0.0013166757,0.00017543379,0.010995082],"genre_scores_gemma":[0.65212893,0.08567933,0.0013043907,0.000328542,0.004411599,0.00023007924,0.0023914028,0.00022248308,0.25330326],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967251,0.00016129426,0.0011551309,0.0010479585,0.00035472962,0.0005557926],"domain_scores_gemma":[0.99823076,0.00003822841,0.00044853354,0.00082070945,0.00030746878,0.00015430893],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006166332,0.0006399946,0.0012131301,0.00046042685,0.000091272515,0.000041430732,0.0005963486,0.0005832675,0.000015804068],"category_scores_gemma":[0.0002662848,0.00060193567,0.000116034054,0.0005362478,0.0002849575,0.0000071769673,0.00039086453,0.00062521297,0.0000018591419],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049848674,0.00016450173,0.0010769118,0.0056487652,0.00033393854,0.00015791834,0.00042826036,0.0003922918,0.5917425,0.000012126207,0.39885175,0.0006925576],"study_design_scores_gemma":[0.0038311458,0.00060953863,0.0078839855,0.007480174,0.00040045884,0.00014947655,0.0007730787,0.0006562838,0.046430305,0.0000061331743,0.9303745,0.001404903],"about_ca_topic_score_codex":0.0009957106,"about_ca_topic_score_gemma":0.0019048705,"teacher_disagreement_score":0.70088637,"about_ca_system_score_codex":0.000112230715,"about_ca_system_score_gemma":0.0003376796,"threshold_uncertainty_score":0.9996432},"labels":[],"label_agreement":null},{"id":"W4407910138","doi":"10.3390/ijms26052005","title":"Insight into crRNA Processing in Streptococcus mutans P42S and Application of SmutCas9 in Genome Editing","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Streptococcus mutans; Trans-activating crRNA; Genome editing; Biology; Computational biology; Genome; Genetics; Gene; Bacteria","score_opus":0.004276712657993702,"score_gpt":0.31327122501853305,"score_spread":0.3089945123605394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407910138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92131346,0.0027534538,0.07508667,0.00024982254,0.00009869675,0.00005398866,8.224533e-7,8.889644e-7,0.0004421805],"genre_scores_gemma":[0.99769545,0.0000981691,0.0020949212,0.000054660126,0.000045993867,0.0000029063547,0.00000154288,0.0000025016557,0.000003881234],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993162,0.000017238277,0.00029081333,0.00012225525,0.0001790636,0.00007442228],"domain_scores_gemma":[0.9996385,0.0000073976244,0.00012447877,0.000045281296,0.00016518054,0.000019156758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031458944,0.000056311408,0.000086397886,0.00026200287,0.000015874142,0.000026721724,0.00024559427,0.000037551275,9.098901e-7],"category_scores_gemma":[0.00009655315,0.00005278757,0.000025341777,0.00021328876,0.00008870172,0.000012704275,0.00006562703,0.000064189335,5.975782e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013154304,0.000029453113,0.019870022,0.000015868409,0.000010404768,0.000011842813,0.00026500667,0.013124938,0.9428581,0.000174338,0.0000012509213,0.023625642],"study_design_scores_gemma":[0.0011024276,0.00020839093,0.088399574,0.00030357536,0.000012440347,0.00005493903,0.0009004204,0.009088214,0.89620733,0.0016230694,0.0019230279,0.00017657946],"about_ca_topic_score_codex":0.000024056013,"about_ca_topic_score_gemma":0.000058018835,"teacher_disagreement_score":0.076381944,"about_ca_system_score_codex":0.000018864595,"about_ca_system_score_gemma":0.00010242627,"threshold_uncertainty_score":0.21526147},"labels":[],"label_agreement":null},{"id":"W4407953551","doi":"10.1016/j.tibtech.2025.01.001","title":"Recombinant DNA: unlocking untapped microbial potential for innovation in crop agriculture","year":2025,"lang":"en","type":"review","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Biotechnology; Recombinant DNA; Agriculture; Crop; Business; Agroforestry; Biology; Agronomy; Gene; Ecology; Genetics","score_opus":0.01342164092035992,"score_gpt":0.3381860608133961,"score_spread":0.32476441989303617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407953551","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00081363495,0.99405867,0.003220448,0.00021936686,0.0009144095,0.00053248386,0.00007482018,0.000046702866,0.000119468736],"genre_scores_gemma":[0.0010741432,0.9938598,0.0011450171,0.00002720809,0.00015771721,0.00019972172,0.0019966136,0.00003899993,0.0015007382],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981734,0.00003798586,0.00071174296,0.0006305956,0.000047172307,0.00039907466],"domain_scores_gemma":[0.999377,0.000012832187,0.00018019746,0.00037748652,0.000037745383,0.000014754201],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001451087,0.00037198415,0.0007930847,0.0013149496,0.000035057303,0.000014537914,0.00036966536,0.0019760095,0.0000062704044],"category_scores_gemma":[0.00008745556,0.00033720754,0.00020028002,0.0016311898,0.00005288385,0.000001709146,0.00021045883,0.0004384277,0.000001528965],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001744322,0.000069044545,0.0000026299085,0.0019718015,0.000055209224,0.000009275235,0.0000059322715,0.000065799846,0.025839118,0.0004729299,0.0019213295,0.9695695],"study_design_scores_gemma":[0.0007092223,0.000129605,0.000012166518,0.0018522897,0.00008465581,0.000035215195,0.00000970092,0.000015136631,0.013996201,0.000054801458,0.9826828,0.00041817658],"about_ca_topic_score_codex":0.000015761862,"about_ca_topic_score_gemma":0.00023331963,"teacher_disagreement_score":0.9807615,"about_ca_system_score_codex":0.000071353534,"about_ca_system_score_gemma":0.00009081021,"threshold_uncertainty_score":0.999908},"labels":[],"label_agreement":null},{"id":"W4407974813","doi":"10.1016/j.jtct.2025.01.754","title":"Unlocking Gene Therapy for Sickle Cell Disease: Addressing the Resource Gap for Patients","year":2025,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Disease; Genetic enhancement; Medicine; Resource (disambiguation); Intensive care medicine; Gene; Internal medicine; Genetics; Computer science; Biology","score_opus":0.01805442768508194,"score_gpt":0.29424402617808726,"score_spread":0.27618959849300534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407974813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75905275,0.009644257,0.23003809,0.00017298818,0.00010927347,0.0007408849,0.00006827018,0.00001343444,0.00016005085],"genre_scores_gemma":[0.9941267,0.0036491214,0.0004556369,0.0004943681,0.00009751258,0.00012129459,0.00060814,0.000019279856,0.0004279559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994563,0.000023991917,0.000120426696,0.00020063434,0.000055311462,0.00014336687],"domain_scores_gemma":[0.9997238,0.00003511081,0.000029168048,0.00013719004,0.00003947359,0.000035244084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099442965,0.00011419461,0.00007567456,0.000024416053,0.0001836636,0.00003246299,0.00008571993,0.000051834122,0.0000026568478],"category_scores_gemma":[0.0000031616355,0.00008824787,0.00007417853,0.00003920007,0.000026273106,0.0000024876178,0.000004246597,0.00003058357,1.6060085e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014862391,0.000103446866,0.001400391,0.00015767434,0.00006650812,4.1241583e-7,0.0004261653,0.00068162754,0.9615642,0.0001255212,0.00048199177,0.033505812],"study_design_scores_gemma":[0.0034246822,0.00016489963,0.0020481336,0.000022485494,0.00003002904,2.7940504e-7,0.000054943168,0.000543041,0.9135989,0.00013943498,0.07982837,0.00014481752],"about_ca_topic_score_codex":0.000001714303,"about_ca_topic_score_gemma":0.0000013157918,"teacher_disagreement_score":0.23507394,"about_ca_system_score_codex":0.0000030710173,"about_ca_system_score_gemma":0.0000203557,"threshold_uncertainty_score":0.35986438},"labels":[],"label_agreement":null},{"id":"W4407987365","doi":"10.1002/cpz1.70109","title":"Engineering Base Changes and Epitope‐Tagged Alleles in Mice Using Cas9 RNA‐Guided Nuclease","year":2025,"lang":"en","type":"article","venue":"Current Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Toronto Centre for Phenogenomics","funders":"National Institutes of Health; Ontario Genomics; Genome Canada","keywords":"Nuclease; Epitope; Cas9; RNA; Allele; CRISPR; Biology; Molecular biology; Computational biology; Genetics; Chemistry; DNA; Gene; Antibody","score_opus":0.030973853152653247,"score_gpt":0.37983318373737623,"score_spread":0.34885933058472296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407987365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96756124,0.0026600058,0.010716767,0.00011666194,0.00020831423,0.01860205,0.00001548188,0.00003262896,0.000086850036],"genre_scores_gemma":[0.9792706,0.00022395002,0.003062558,0.00008890464,0.00026967694,0.016914766,0.000031080617,0.000040572282,0.00009789295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992081,0.000023547513,0.00017831245,0.000298319,0.00006114153,0.00023061113],"domain_scores_gemma":[0.99966633,0.000010171389,0.000030868538,0.00019584082,0.000031635773,0.000065176064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014873016,0.00016042926,0.00014757212,0.00010874574,0.000034965506,0.00003437308,0.00011372771,0.00007773933,0.0000068181703],"category_scores_gemma":[0.00009747796,0.00017071722,0.000033384404,0.00012539102,0.000020207981,0.000003817747,0.0001283814,0.000104698884,0.000001078146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038328926,0.000055327582,0.0010597514,0.000446126,0.000016794771,0.0000044862227,0.000051476734,0.002031921,0.974895,0.000061995495,0.0004421043,0.020896703],"study_design_scores_gemma":[0.0017917127,0.00008711667,0.002453048,0.00081527414,0.000021690732,0.000011917205,0.000050027822,0.02047607,0.86699384,0.00002006933,0.10683826,0.00044097603],"about_ca_topic_score_codex":0.000014526072,"about_ca_topic_score_gemma":0.000027838496,"teacher_disagreement_score":0.107901156,"about_ca_system_score_codex":0.000019734063,"about_ca_system_score_gemma":0.000042989628,"threshold_uncertainty_score":0.6961646},"labels":[],"label_agreement":null},{"id":"W4408023952","doi":"10.1128/spectrum.03012-24","title":"Novel application of ribonucleoprotein-mediated CRISPR-Cas9 gene editing in plant pathogenic oomycete species","year":2025,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Natural Resources Canada; Canadian Forest Service; University of British Columbia","funders":"Natural Resources Canada; FPInnovations; Natural Sciences and Engineering Research Council of Canada; Canadian Food Inspection Agency; Genome Canada","keywords":"CRISPR; Oomycete; Biology; Cas9; Genome editing; Genetics; Phytophthora cactorum; Gene; Phytophthora; Pythium ultimum; Rhizoctonia solani; Botany","score_opus":0.004090178168757901,"score_gpt":0.2340967288520549,"score_spread":0.230006550683297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408023952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9376823,0.0014540445,0.059070088,0.00034306324,0.0002808526,0.00034250348,0.00030982602,0.000021617077,0.0004957342],"genre_scores_gemma":[0.9969092,0.000105059094,0.0017842163,0.00012199245,0.00015914947,0.000031070518,0.000679582,0.000015286072,0.00019445192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989244,0.000025138132,0.00033942165,0.00037176476,0.000028724307,0.00031056488],"domain_scores_gemma":[0.99952614,0.000018362542,0.00008692482,0.00031270715,0.000027817978,0.000028052993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016435148,0.00016899178,0.00022940342,0.00013719025,0.00003550889,0.0000057829584,0.00019991193,0.00022028507,0.000012596227],"category_scores_gemma":[0.00005370688,0.00017625678,0.00007644867,0.00019058549,0.000090004396,0.0000018686504,0.00013057716,0.00012777708,0.0000069758826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040365067,0.000051119572,0.0050528776,0.00003129616,0.000039383554,0.0000019814954,0.000025554109,0.00020928777,0.99389267,0.00015546655,0.00023629465,0.000263693],"study_design_scores_gemma":[0.0006594194,0.000078647754,0.013956377,0.000020474321,0.000013549808,0.00003452195,0.00005366047,0.00020186971,0.97136635,0.000037767222,0.0134231,0.00015426762],"about_ca_topic_score_codex":0.00007955821,"about_ca_topic_score_gemma":0.00039370055,"teacher_disagreement_score":0.059226923,"about_ca_system_score_codex":0.00002569832,"about_ca_system_score_gemma":0.000043991437,"threshold_uncertainty_score":0.7187543},"labels":[],"label_agreement":null},{"id":"W4408050011","doi":"10.1016/j.rpth.2025.102710","title":"Development of a novel gene editing lexicon for hemophilia: methodology and results","year":2025,"lang":"en","type":"article","venue":"Research and Practice in Thrombosis and Haemostasis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Hemophilia Society","funders":"Regeneron Pharmaceuticals","keywords":"Lexicon; Computer science; Computational biology; Natural language processing; Artificial intelligence; Biology","score_opus":0.2585965175060801,"score_gpt":0.5192134525889633,"score_spread":0.26061693508288325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408050011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9618625,0.0068100467,0.02546132,0.0042639957,0.00007201455,0.00046706235,0.00005883093,0.000004489573,0.0009997485],"genre_scores_gemma":[0.7046653,0.0075593176,0.28742102,0.00009761239,0.00007210121,0.00005858042,0.00003691395,0.0000115431885,0.00007759861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998941,0.000107229316,0.00029047136,0.00032058643,0.000097144104,0.0002435923],"domain_scores_gemma":[0.9985055,0.0010915644,0.000054797354,0.00013113275,0.00015818448,0.000058829635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003157743,0.00009213772,0.00018466484,0.00012652633,0.00012901358,0.000029664825,0.000060204322,0.000117495125,7.717607e-7],"category_scores_gemma":[0.0032727544,0.00008962942,0.000016003996,0.00013845498,0.00013110014,0.000009282527,0.00019083929,0.00012244539,5.4128343e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00094302226,0.00016324705,0.00038400086,0.0003252611,0.00016836307,9.338986e-7,0.0012191217,0.000016464388,0.86994547,0.0012128638,0.0005280838,0.12509319],"study_design_scores_gemma":[0.0034656483,0.00051473745,0.005909843,0.0001432033,0.00004188991,0.000023628105,0.004257548,0.00031501398,0.9003655,0.00054863485,0.08421077,0.00020361638],"about_ca_topic_score_codex":0.000056352546,"about_ca_topic_score_gemma":0.00012126761,"teacher_disagreement_score":0.2619597,"about_ca_system_score_codex":0.0000087124745,"about_ca_system_score_gemma":0.000103895436,"threshold_uncertainty_score":0.3918029},"labels":[],"label_agreement":null},{"id":"W4408129732","doi":"10.1016/j.molp.2025.03.002","title":"SuperDecode: An integrated toolkit for analyzing mutations induced by genome editing","year":2025,"lang":"en","type":"article","venue":"Molecular Plant","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Major Science and Technology Projects of China","keywords":"Biology; Genome editing; Computational biology; Genome; Genetics; Mutation; Gene","score_opus":0.006852138082357719,"score_gpt":0.28598186889533095,"score_spread":0.2791297308129732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408129732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.61718327,0.00047316044,0.38163155,0.00008173669,0.00011700579,0.00017399009,0.0001806061,0.000020250549,0.00013839011],"genre_scores_gemma":[0.99244076,0.000015179953,0.0036373222,0.00022114502,0.00007499501,0.000060295974,0.003370836,0.00002170881,0.00015777512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918896,0.000024730178,0.00018543801,0.0003030524,0.00006045433,0.0002373471],"domain_scores_gemma":[0.99959666,0.000011748207,0.000026617867,0.00023300963,0.00006797866,0.00006401119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001221354,0.00014320906,0.0001235662,0.00007183768,0.00008769199,0.00004480167,0.0001524149,0.00011509678,0.0000062860195],"category_scores_gemma":[0.00009651325,0.00015105799,0.00007081556,0.00011998027,0.000015427013,0.000003422424,0.00004090365,0.00007728091,0.0000013378976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014699523,0.000026801794,0.000085332395,0.000018740679,0.000069879934,0.000002910298,0.00003273671,0.0014681601,0.996291,0.00010839805,0.00049891265,0.0013824707],"study_design_scores_gemma":[0.0004967423,0.00014980792,0.00030511056,0.00002009769,0.00005629543,0.0000066495268,0.00016467646,0.0035725534,0.9647424,0.000054559852,0.030198853,0.00023225539],"about_ca_topic_score_codex":0.00002246589,"about_ca_topic_score_gemma":0.00003075847,"teacher_disagreement_score":0.37799424,"about_ca_system_score_codex":0.00001590792,"about_ca_system_score_gemma":0.000055437085,"threshold_uncertainty_score":0.6159966},"labels":[],"label_agreement":null},{"id":"W4408142346","doi":"10.1093/nar/gkaf105","title":"Packaged delivery of CRISPR–Cas9 ribonucleoproteins accelerates genome editing","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Emerson Collective; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; CRISPR; Genome editing; Ribonucleoprotein; Cas9; Genetics; Computational biology; Guide RNA; Genome; Gene; RNA","score_opus":0.024923208584006637,"score_gpt":0.36536552270463507,"score_spread":0.3404423141206284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408142346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98452586,0.0018271314,0.0039176936,0.00026714688,0.00013069762,0.00028474018,0.000023084332,0.000021670403,0.009001963],"genre_scores_gemma":[0.99661344,0.00038445566,0.0012068317,0.00005385559,0.00028255596,0.000030991145,0.000037394693,0.000028015413,0.0013624595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844134,0.00010603605,0.0002700984,0.00037882433,0.00031690797,0.00048677437],"domain_scores_gemma":[0.9989088,0.00004305714,0.00003415629,0.0005106826,0.00041501594,0.00008829656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070791575,0.00014505896,0.00018375702,0.00020852777,0.00017620756,0.000049683087,0.00042574498,0.0001875322,0.00009117259],"category_scores_gemma":[0.0003273714,0.00014758985,0.00009529497,0.00040954872,0.00018695535,0.000006092824,0.00044041165,0.00031685038,0.000023134973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050573442,0.00005042179,0.0025344898,0.00010647793,0.00006195015,0.0000046746914,0.00007477834,0.00011689179,0.9887233,0.000175154,0.0028060519,0.0052952855],"study_design_scores_gemma":[0.00046414338,0.00022130422,0.01350966,0.00005123536,0.000010169132,0.000003271904,0.00051952415,0.00029414598,0.9491011,0.00016026493,0.035510525,0.00015467044],"about_ca_topic_score_codex":0.000066567816,"about_ca_topic_score_gemma":0.00002223604,"teacher_disagreement_score":0.039622165,"about_ca_system_score_codex":0.00002822053,"about_ca_system_score_gemma":0.00012223792,"threshold_uncertainty_score":0.6018539},"labels":[],"label_agreement":null},{"id":"W4408184346","doi":"10.26685/urncst.680","title":"Zinc Finger Nucleases (ZFNs) and Gene Therapy Applications","year":2025,"lang":"en","type":"article","venue":"Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Zinc finger nuclease; Genome editing; Biology; Gene; DNA; Computational biology; Non-homologous end joining; Genetics; Nuclease; DNA repair; Gene targeting; Zinc finger; Genome","score_opus":0.02801996828005731,"score_gpt":0.4362655855191194,"score_spread":0.4082456172390621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408184346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95757425,0.021556666,0.00041664144,0.019851614,0.00009568938,0.00019044569,0.0000014200292,0.000012187044,0.0003011142],"genre_scores_gemma":[0.9458512,0.053065263,0.0006279254,0.000151927,0.00007864093,0.000008626541,0.0000010701663,0.0000043617915,0.0002109653],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99865115,0.000057814035,0.00026533136,0.00040346026,0.00022246724,0.0003998022],"domain_scores_gemma":[0.99929965,0.000106575426,0.000036963895,0.00017337153,0.00024354974,0.00013989904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017777265,0.00010178905,0.00014766354,0.00039382317,0.0004982438,0.00011870439,0.00029268433,0.00018340851,0.000002105142],"category_scores_gemma":[0.00041461937,0.00007557922,0.000027635717,0.00091157237,0.0017993506,0.000014900578,0.0003501598,0.00075312867,0.0000012719021],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009551097,0.00017712235,0.045054987,0.000023141267,0.00006320423,0.000021398491,0.000012927375,0.0000051052057,0.23814788,0.007499275,0.0011591425,0.7077403],"study_design_scores_gemma":[0.00835716,0.0033072787,0.15845914,0.00039394014,0.00005442509,0.0015236838,0.0014666189,0.0045990446,0.16310748,0.38207167,0.27539244,0.0012671043],"about_ca_topic_score_codex":0.0000099989675,"about_ca_topic_score_gemma":0.000026576063,"teacher_disagreement_score":0.7064732,"about_ca_system_score_codex":0.000020163969,"about_ca_system_score_gemma":0.00018829618,"threshold_uncertainty_score":0.66297823},"labels":[],"label_agreement":null},{"id":"W4408213337","doi":"10.1021/acs.nanolett.5c00285","title":"A Semiconducting Polymer NanoCRISPR for Near-Infrared Photoactivatable Gene Editing and Cancer Gene Therapy","year":2025,"lang":"en","type":"article","venue":"Nano Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"Fundamental Research Funds for the Central Universities; Science and Technology Commission of Shanghai Municipality; Donghua University; Fundo para o Desenvolvimento das Ciências e da Tecnologia; Universidade de Macau; National Natural Science Foundation of China; Natural Science Foundation of Xiamen City","keywords":"Gene; Genetic enhancement; Polymer; Infrared; Cancer; Cancer research; Biology; Genetics; Nanotechnology; Medicine; Computational biology; Chemistry; Materials science; Physics; Optics; Organic chemistry","score_opus":0.008912498019303645,"score_gpt":0.2924127555946608,"score_spread":0.28350025757535713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408213337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9765491,0.01102692,0.010696325,0.00082157715,0.0005044378,0.00025930902,0.00003647613,0.000020722557,0.00008512106],"genre_scores_gemma":[0.9874176,0.00063218013,0.004400959,0.0054062954,0.00067481893,0.00018859979,0.00006841782,0.0000422406,0.0011688845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999143,0.00001333319,0.0001509762,0.0003347829,0.000059848662,0.00029806487],"domain_scores_gemma":[0.9996586,0.00001837904,0.0000433056,0.00020150657,0.000034464396,0.000043748296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008818256,0.00015834876,0.00013877348,0.000040367584,0.00015038495,0.000049069637,0.00010141226,0.000091777205,0.0000097125785],"category_scores_gemma":[0.00002645413,0.000160153,0.000064337386,0.0000874967,0.000040837116,0.000005580697,0.00005424802,0.000055057793,3.213198e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037898226,0.0000101652795,0.00080139283,0.000025663621,0.000089751804,6.7128707e-7,0.000064579384,0.00014755591,0.98698837,0.0000024147341,0.0063082166,0.0055233496],"study_design_scores_gemma":[0.00080651476,0.000028151795,0.000144149,0.000021807211,0.000016668972,0.0000051663146,0.000046319255,0.00013131222,0.95507437,0.000004429937,0.043561198,0.00015992665],"about_ca_topic_score_codex":0.00008260816,"about_ca_topic_score_gemma":0.0000043211435,"teacher_disagreement_score":0.03725298,"about_ca_system_score_codex":0.000016055805,"about_ca_system_score_gemma":0.000047038186,"threshold_uncertainty_score":0.653085},"labels":[],"label_agreement":null},{"id":"W4408293704","doi":"10.1038/s41467-025-57514-1","title":"Discovery of the widespread site-specific single-stranded nuclease family Ssn","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina; Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Ministère de la Santé et des Services sociaux; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada; Ministère de la Santé; Government of Canada","keywords":"Nuclease; Computational biology; Genetics; Biology; DNA","score_opus":0.011729848296249032,"score_gpt":0.29649574012389696,"score_spread":0.28476589182764794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408293704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93645245,0.038789082,0.00459285,0.0024347554,0.00051549665,0.00031603244,0.00010280382,0.000023890634,0.016772654],"genre_scores_gemma":[0.99688256,0.0008981516,0.0011755668,0.00028282462,0.00002486804,0.000009129756,0.000067832945,0.000008821122,0.0006502581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953204,0.00004464579,0.00014469202,0.00012462391,0.000063649924,0.000090325964],"domain_scores_gemma":[0.99821895,0.0000475101,0.00003932386,0.0016104938,0.000068339046,0.000015397514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006608761,0.00008257434,0.00008053063,0.000028442806,0.00010104044,0.000019267547,0.00070821034,0.00016664587,0.0000014617872],"category_scores_gemma":[0.00009042208,0.00006696795,0.000099124154,0.0001646611,0.00011491496,0.0000024956637,0.00033009096,0.00025556737,0.0000012079274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014195806,0.000074226,0.0010547698,0.000008942478,0.000024794464,5.7475777e-8,0.00003203548,0.000091858965,0.988501,0.0019097571,0.0074076494,0.00088072097],"study_design_scores_gemma":[0.00040256945,0.000030719253,0.03310901,0.00007215708,0.000039807444,0.0000015976818,0.00012731677,0.000085782485,0.6212569,0.00015795667,0.3445745,0.00014170795],"about_ca_topic_score_codex":0.0000070844662,"about_ca_topic_score_gemma":0.00015238045,"teacher_disagreement_score":0.36724412,"about_ca_system_score_codex":0.0000102491485,"about_ca_system_score_gemma":0.00003758013,"threshold_uncertainty_score":0.27308738},"labels":[],"label_agreement":null},{"id":"W4408327252","doi":"10.1016/j.bios.2025.117364","title":"dPAFS: A nuclease-dead PfAgo-mediated fluorescence sensing platform for genotyping genome-edited rice","year":2025,"lang":"en","type":"article","venue":"Biosensors and Bioelectronics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences","keywords":"Genotyping; Nuclease; Computational biology; Biology; Chemistry; Genetics; DNA; Gene; Genotype","score_opus":0.006908363733145473,"score_gpt":0.2649352742221585,"score_spread":0.25802691048901305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408327252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97031194,0.0064899977,0.021834912,0.0003060154,0.00023656909,0.00047273585,0.00006082843,0.00006641462,0.000220568],"genre_scores_gemma":[0.9928407,0.0016002022,0.004367721,0.00035015293,0.00024047545,0.0000081142025,0.00018437336,0.000034907975,0.00037337118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870086,0.000014026654,0.00023809394,0.000442899,0.000083264415,0.0005208378],"domain_scores_gemma":[0.9994581,0.000038804406,0.000056654444,0.0002520927,0.0001018154,0.00009253756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015365804,0.00023507187,0.00019454454,0.000104831226,0.00018634024,0.000052498093,0.00012206653,0.00022437637,0.0000019556987],"category_scores_gemma":[0.00012158901,0.00023022124,0.0000922799,0.00021303476,0.00006916279,0.00000448467,0.00008231503,0.00012128848,0.0000026088933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012303054,0.000021216676,0.000049243405,0.00008572487,0.00008473673,0.0000020527605,0.000039930026,0.000051431394,0.99100024,0.00023510438,0.00046401136,0.007843311],"study_design_scores_gemma":[0.0020035007,0.00075227366,0.0017659585,0.000080741986,0.00014273482,0.0000494186,0.00026272412,0.023471167,0.78365874,0.00023565424,0.186736,0.0008411018],"about_ca_topic_score_codex":0.000016248126,"about_ca_topic_score_gemma":0.00003319768,"teacher_disagreement_score":0.20734149,"about_ca_system_score_codex":0.000038018297,"about_ca_system_score_gemma":0.00010220301,"threshold_uncertainty_score":0.93881494},"labels":[],"label_agreement":null},{"id":"W4408399205","doi":"10.1101/2025.03.11.642632","title":"Targeting dCas9-SunTag to a susceptibility gene promoter is sufficient for CRISPR interference","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"CRISPR; Genetics; Gene; Biology; Interference (communication); RNA interference; Computational biology; Computer science; Computer network; RNA","score_opus":0.01147900070208788,"score_gpt":0.27666548156116744,"score_spread":0.26518648085907953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408399205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7482923,0.0010883164,0.2464423,0.00025386616,0.0012408353,0.0016787228,0.00088853925,0.000106745814,0.000008332851],"genre_scores_gemma":[0.9761513,0.00010972964,0.021884678,0.00053714425,0.0006248357,0.00054944993,0.000004935178,0.000087512795,0.00005041946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967878,0.00006394939,0.0006161388,0.0016090821,0.00021085278,0.0007121838],"domain_scores_gemma":[0.99743146,0.000025788902,0.00017052867,0.0014646287,0.00062570453,0.00028190535],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00061092264,0.00062150456,0.00050767814,0.00017757122,0.00013630641,0.00014439883,0.000716866,0.0005826372,0.00002343962],"category_scores_gemma":[0.00040074915,0.0006884979,0.0002734684,0.0002399572,0.000058341127,0.0000049923096,0.0010680072,0.00038284177,0.000015728987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000860958,0.00012406614,0.0012605743,0.0005796565,0.00012492012,0.0000031739316,0.000037642618,0.0010581447,0.99427783,0.00001653614,0.0024255912,0.000005746299],"study_design_scores_gemma":[0.0003742499,0.00022355455,0.0031484633,0.00021359009,0.00008357282,1.48863615e-8,0.000007829767,0.0012001924,0.97814906,9.215584e-7,0.015834484,0.0007640435],"about_ca_topic_score_codex":0.000029139506,"about_ca_topic_score_gemma":0.0000067134597,"teacher_disagreement_score":0.22785896,"about_ca_system_score_codex":0.00013249366,"about_ca_system_score_gemma":0.00045128705,"threshold_uncertainty_score":0.9995566},"labels":[],"label_agreement":null},{"id":"W4408417098","doi":"10.54254/2753-8818/2025.21435","title":"Advancements in CRISPR Technologies and Treatment of Genetic Disorders","year":2025,"lang":"en","type":"article","venue":"Theoretical and Natural Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Computational biology; Computer science; Data science; Genetics; Gene","score_opus":0.0019417537721882893,"score_gpt":0.28257107617936433,"score_spread":0.28062932240717603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408417098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990985,0.00735628,0.00097143615,0.0002223957,0.00004177617,0.000078431156,9.65266e-7,0.0000053363633,0.0003384027],"genre_scores_gemma":[0.9959412,0.0032027706,0.00080736715,0.000012614726,0.0000031191057,0.0000047266935,5.342707e-7,0.0000013152463,0.000026358706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99958223,0.000004877529,0.00007313729,0.00017137814,0.000045488927,0.00012290584],"domain_scores_gemma":[0.99986756,0.00000992388,0.0000081745475,0.000086740685,0.000010775708,0.000016851478],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048701688,0.000058234134,0.000066525565,0.000052436895,0.0000293975,0.0000062161766,0.00007295938,0.000029718949,0.0000012252467],"category_scores_gemma":[0.000048814032,0.0000415894,0.0000099356075,0.00015045352,0.0009257761,0.0000020596078,0.00007963757,0.000022363647,7.51512e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005793254,0.000051047336,0.032019176,0.000018695991,0.0000066995412,6.622659e-7,0.000050198003,0.000029987978,0.50241137,0.049688805,0.000003485429,0.41566193],"study_design_scores_gemma":[0.0008786396,0.0005795728,0.21193515,0.000036877133,0.0000126006125,0.000003980828,0.00033999095,0.0014557041,0.75563884,0.027463589,0.001475639,0.00017941487],"about_ca_topic_score_codex":0.000006648495,"about_ca_topic_score_gemma":0.000013016261,"teacher_disagreement_score":0.41548252,"about_ca_system_score_codex":0.0000056339786,"about_ca_system_score_gemma":0.000015683565,"threshold_uncertainty_score":0.34110606},"labels":[],"label_agreement":null},{"id":"W4408486376","doi":"10.1101/2025.03.12.642913","title":"Engineering Conjugative Plasmids for Inducible Horizontal DNA Transfer","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Plasmid; Horizontal gene transfer; Biology; Gene; Biotechnology; CRISPR; Antimicrobial; Computational biology; Gene transfer; Genetics; Biochemical engineering; Microbiology; Genome; Engineering","score_opus":0.008417646701036974,"score_gpt":0.2432479778711372,"score_spread":0.23483033117010021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408486376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8423956,0.0015153002,0.15160348,0.00007330926,0.0019033146,0.0011636958,0.0011427265,0.00017346525,0.000029109273],"genre_scores_gemma":[0.9913442,0.00022191244,0.0069239135,0.000085809785,0.0007429,0.0005323045,0.0000056731346,0.00011148625,0.000031784544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997806,0.000028665187,0.00041030938,0.0010272976,0.00017352532,0.0005541867],"domain_scores_gemma":[0.998553,0.000037392856,0.00006582512,0.00087368774,0.0002793405,0.00019076475],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028659296,0.0005779233,0.00046923012,0.00018397003,0.00009283321,0.00008878284,0.0004566116,0.00076664786,0.000011274321],"category_scores_gemma":[0.00017415704,0.00068830035,0.0002755777,0.000187753,0.000053401287,0.0000063380894,0.00028558998,0.00042964923,0.00000569546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053914922,0.000052059848,0.00020962363,0.00050428277,0.0003006055,0.000003911365,0.000007760495,0.0020565337,0.9959316,0.00039339243,0.0004830663,0.0000032102082],"study_design_scores_gemma":[0.0007347167,0.0001322554,0.0017150928,0.00023576297,0.00011829754,1.7306276e-8,0.0000031899278,0.0010609176,0.9722942,8.427172e-7,0.022974214,0.0007304923],"about_ca_topic_score_codex":0.000011125717,"about_ca_topic_score_gemma":0.0000032116336,"teacher_disagreement_score":0.14894862,"about_ca_system_score_codex":0.000085837164,"about_ca_system_score_gemma":0.00043726581,"threshold_uncertainty_score":0.99955684},"labels":[],"label_agreement":null},{"id":"W4408534952","doi":"10.1079/ab.2025.0024","title":"Managing regulatory issues arising from new diagnostic technologies: High throughput sequencing as a case study","year":2025,"lang":"en","type":"article","venue":"CABI Agriculture and Bioscience","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Government of Canada; Canadian Food Inspection Agency","funders":"","keywords":"Throughput; DNA sequencing; Computational biology; Computer science; Biology; Genetics; Telecommunications; Gene","score_opus":0.005844315635480461,"score_gpt":0.2783570485248283,"score_spread":0.27251273288934785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408534952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868603,0.0075689238,0.004291675,0.0006030298,0.00022043378,0.00023518788,0.000004004987,0.00006962221,0.00014682442],"genre_scores_gemma":[0.9973231,0.0004715307,0.001128097,0.0001557461,0.00011188953,0.0000097819775,0.000006607114,0.000005003294,0.00078825623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900424,0.000016727961,0.0001454869,0.0005146894,0.00010233466,0.0002165366],"domain_scores_gemma":[0.99955505,0.000032827877,0.000035476776,0.0002876096,0.00003663225,0.000052396845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000878828,0.0001705155,0.00013912395,0.000045757453,0.00019346365,0.00009037688,0.00019219308,0.00012603987,0.0000021209803],"category_scores_gemma":[0.00018923711,0.00012214099,0.000032056574,0.00029758137,0.00009122519,0.0000098526125,0.0002328054,0.000104306986,0.0000013998701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000051771535,0.00004774493,0.0070645893,0.000024644902,0.000049591654,0.0004672089,0.0009709952,0.00033414722,0.96823347,0.00015628405,0.002562352,0.020083785],"study_design_scores_gemma":[0.0007838234,0.00045398888,0.021556187,0.00023024551,0.00015354808,0.00066373515,0.0493342,0.00013533991,0.916491,0.002326396,0.007156128,0.000715451],"about_ca_topic_score_codex":0.0019422226,"about_ca_topic_score_gemma":0.00033111213,"teacher_disagreement_score":0.05174252,"about_ca_system_score_codex":0.00002341253,"about_ca_system_score_gemma":0.00005619114,"threshold_uncertainty_score":0.4980765},"labels":[],"label_agreement":null},{"id":"W4408644416","doi":"10.1007/978-1-0716-4358-7_2","title":"Accelerated Laboratory Evolution of Conjugative Plasmids for CRISPR Delivery in Bacteria","year":2025,"lang":"en","type":"book-chapter","venue":"Springer protocols handbooks/Springer protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"CRISPR; Plasmid; Bacteria; Biology; Computational biology; Genetics; Microbiology; DNA; Gene","score_opus":0.02210713138760932,"score_gpt":0.331061220958909,"score_spread":0.30895408957129966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408644416","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020078784,0.0005653948,0.019825704,0.000033368062,0.00028954356,0.95263636,0.0008474743,0.00016087561,0.023633411],"genre_scores_gemma":[0.004608294,0.000031045423,0.006105922,0.00007019802,0.0004744693,0.95567226,0.00014160448,0.00024929066,0.032646928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99598,0.00007989987,0.0014384246,0.0013477961,0.00040510375,0.0007487336],"domain_scores_gemma":[0.9970076,0.000072985735,0.00069362816,0.0011996133,0.000843225,0.00018296513],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006940473,0.0009894806,0.0011734507,0.0005175489,0.00010753234,0.00010365041,0.00076801336,0.0011980097,0.00011118078],"category_scores_gemma":[0.0001659366,0.0010981476,0.00042739772,0.00013801917,0.00023155552,0.000025267504,0.0005050155,0.00057801115,0.000013928136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036738373,0.00032324356,0.0014092634,0.0066069807,0.0006827052,0.000017952425,0.00017187813,0.0004404043,0.97092277,0.008468703,0.0024935578,0.00478869],"study_design_scores_gemma":[0.0038263595,0.0009460096,0.0005225499,0.0049960148,0.000060712846,0.0000023129421,0.0000129219325,0.00011092434,0.65128535,0.0006131323,0.33660203,0.0010216624],"about_ca_topic_score_codex":0.000023081904,"about_ca_topic_score_gemma":0.00007495439,"teacher_disagreement_score":0.33410847,"about_ca_system_score_codex":0.00029647272,"about_ca_system_score_gemma":0.0011534864,"threshold_uncertainty_score":0.9991469},"labels":[],"label_agreement":null},{"id":"W4408687580","doi":"10.3390/ijms26072835","title":"Universal Prime Editing Therapeutic Strategy for RyR1-Related Myopathies: A Protective Mutation Rescues Leaky RyR1 Channel","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"RYR-1 Foundation","keywords":"RYR1; Mutation; Genome editing; Biology; Genetics; Gene; Computational biology; Intracellular; CRISPR; Ryanodine receptor","score_opus":0.011348942605905134,"score_gpt":0.3251203174544666,"score_spread":0.3137713748485615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408687580","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.470203,0.0022654906,0.52490383,0.0008657316,0.0009166526,0.00021027237,0.0000072114626,0.0000075821135,0.0006202008],"genre_scores_gemma":[0.99847484,0.00004513013,0.0011156544,0.00010834606,0.00014939955,0.0000067090177,0.000005735746,0.0000061839955,0.00008799773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999161,0.000037322377,0.00024734615,0.00016759966,0.00025533733,0.0001314145],"domain_scores_gemma":[0.9992838,0.000021633956,0.0001650846,0.00006028097,0.0004390093,0.000030191406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004294582,0.0000930703,0.00009496413,0.00018349673,0.00007518785,0.00006750665,0.0003667934,0.00006624777,0.000002994634],"category_scores_gemma":[0.0001480823,0.000083399704,0.00010922825,0.00013332137,0.00010316311,0.00001719034,0.000046110345,0.000088080524,3.969506e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014428332,0.000061767954,0.00008481671,0.000015051059,0.0003733695,0.000038302598,0.00032517748,0.05910919,0.91562486,0.0022447123,0.00006503359,0.021913411],"study_design_scores_gemma":[0.0011737604,0.00093889725,0.00086195755,0.00015446897,0.00004883111,0.00013527849,0.0021750983,0.0091233,0.9774759,0.006701428,0.0010341887,0.00017693677],"about_ca_topic_score_codex":0.000008490994,"about_ca_topic_score_gemma":0.0000048668508,"teacher_disagreement_score":0.52827185,"about_ca_system_score_codex":0.000030583247,"about_ca_system_score_gemma":0.00020396187,"threshold_uncertainty_score":0.34009412},"labels":[],"label_agreement":null},{"id":"W4408721834","doi":"10.1016/j.ymthe.2025.03.013","title":"Try before you buy: Empirical comparison of base editing approaches","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Ögonfonden; National Eye Institute; University of Southern California; Research to Prevent Blindness; Knights Templar Eye Foundation","keywords":"Base (topology); Computer science; Computational biology; Biology; Mathematics","score_opus":0.029320653860558505,"score_gpt":0.35198218851222235,"score_spread":0.32266153465166386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408721834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89294124,0.005106136,0.10002905,0.0003246116,0.00015164078,0.00014962452,0.0000063003004,0.000016590018,0.0012748075],"genre_scores_gemma":[0.99720556,0.000038777293,0.0020480512,0.00025821294,0.00010457504,0.000018657516,0.000065703935,0.000020339377,0.00024011113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991615,0.000039090286,0.00022907906,0.00026776397,0.00011117991,0.00019138804],"domain_scores_gemma":[0.9995157,0.000006114414,0.00004796332,0.00034774016,0.00003865618,0.000043801243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011708713,0.00014990401,0.00019533712,0.00005622486,0.00003958719,0.000011969697,0.0001765085,0.00013919448,0.000009344995],"category_scores_gemma":[0.000031313073,0.0001434727,0.00013258679,0.00013094142,0.00005292882,0.0000013525147,0.00006022816,0.00009644069,0.0000014095389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006672092,0.00017257275,0.017801698,0.000047006688,0.00016006979,0.0000033274416,0.00024712822,0.0021755768,0.94091266,0.00019721217,0.0011088776,0.037107132],"study_design_scores_gemma":[0.00059692725,0.00019009064,0.0022901422,0.000018975721,0.000014679367,0.000001979434,0.00021852509,0.0015817845,0.9780561,0.00010607863,0.016797988,0.00012675507],"about_ca_topic_score_codex":0.0000051978586,"about_ca_topic_score_gemma":0.0000040485243,"teacher_disagreement_score":0.10426433,"about_ca_system_score_codex":0.000007184611,"about_ca_system_score_gemma":0.000038338603,"threshold_uncertainty_score":0.5850647},"labels":[],"label_agreement":null},{"id":"W4408766124","doi":"10.1007/s12032-025-02692-7","title":"Retraction Note: Molecular and therapeutic effect of CRISPR in treating cancer","year":2025,"lang":"en","type":"article","venue":"Medical Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Hematology; CRISPR; Medicine; Internal medicine; Cancer; Computational biology; Biology; Oncology; Genetics; Gene","score_opus":0.003961528702442092,"score_gpt":0.3733236946983364,"score_spread":0.3693621659958943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408766124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9757582,0.004901541,0.016847331,0.0007041692,0.00028447533,0.00010820287,9.4778045e-7,0.000004611011,0.0013904985],"genre_scores_gemma":[0.99903715,0.00039970703,0.0001387849,0.0002713611,0.000049770282,0.000026544165,0.0000036927165,0.0000052133696,0.00006775974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994235,0.00008478165,0.00015128989,0.00015038312,0.000075374424,0.00011467015],"domain_scores_gemma":[0.9997632,0.00007292716,0.00002572871,0.00008578189,0.000014203425,0.00003814146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002961132,0.00006992381,0.0001658996,0.000047371217,0.000011288322,0.0000016111147,0.000056413868,0.00029738614,0.00002287982],"category_scores_gemma":[0.0002332033,0.00005968184,0.000028042212,0.000080839454,0.000057779882,5.574523e-7,0.000038538168,0.00014556047,2.6567562e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010812379,0.000033271437,0.014159916,0.00008287422,0.00003124157,0.000012758644,0.000034608132,0.00014921748,0.6152841,0.00005134646,0.00011518479,0.3699374],"study_design_scores_gemma":[0.0017197909,0.0008672031,0.017431274,0.00008536265,0.00004847991,0.000013282039,0.000023364772,0.0016603614,0.9531079,0.000047627258,0.024893427,0.000101963786],"about_ca_topic_score_codex":0.00009623471,"about_ca_topic_score_gemma":0.00016174783,"teacher_disagreement_score":0.36983544,"about_ca_system_score_codex":0.000022113367,"about_ca_system_score_gemma":0.00009003261,"threshold_uncertainty_score":0.24337547},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"agree"},{"id":"W4408779184","doi":"10.1016/j.tips.2025.02.009","title":"CRISPR/Cas technologies for cancer drug discovery and treatment","year":2025,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"CRISPR; Drug discovery; Cancer; Drug; Computational biology; Medicine; Psychology; Bioinformatics; Biology; Pharmacology; Genetics; Internal medicine; Gene","score_opus":0.05677666338263857,"score_gpt":0.4768608938977405,"score_spread":0.4200842305151019,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408779184","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005254899,0.9979643,0.00016201266,0.00017911357,0.0002819064,0.0003433968,0.00010195375,0.000029250543,0.00041254758],"genre_scores_gemma":[0.0020240971,0.9947261,0.00036415187,0.000025380157,0.00009229701,0.00079818285,0.000033210872,0.000006703268,0.0019298727],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987342,0.000037286798,0.00023744705,0.00060169067,0.000071435585,0.0003179729],"domain_scores_gemma":[0.999691,0.00010022217,0.00006385955,0.00010281411,0.000009602679,0.00003249863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016730544,0.0002802471,0.0005441756,0.0001856909,0.00009455462,0.000049736234,0.00031955098,0.00019733454,0.000015152871],"category_scores_gemma":[0.00003794561,0.00017262378,0.00017898381,0.00038487196,0.0002645649,0.0000045267743,0.00018594206,0.00009035777,3.029594e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000064112783,0.000043310298,0.000036118763,0.0003807173,0.000043760578,0.0000021532671,0.000006939783,0.000042077896,0.00016200381,0.000040850664,0.00093644625,0.9982992],"study_design_scores_gemma":[0.00027446696,0.0002546115,0.00002492831,0.0004300789,0.00024747165,0.0000035135276,0.00003695228,0.000030755964,0.0028339094,0.000049063703,0.99553883,0.00027539107],"about_ca_topic_score_codex":0.000021307707,"about_ca_topic_score_gemma":0.000108589615,"teacher_disagreement_score":0.9980238,"about_ca_system_score_codex":0.000048915514,"about_ca_system_score_gemma":0.00009848919,"threshold_uncertainty_score":0.7039394},"labels":[],"label_agreement":null},{"id":"W4408836821","doi":"10.1021/acssynbio.4c00786","title":"Ultra-efficient Integration of Gene Libraries onto Yeast Cytosolic Plasmids","year":2025,"lang":"en","type":"letter","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; Hewitt Foundation; National Eye Institute","keywords":"Plasmid; Yeast; Gene; Biology; Cytosol; Synthetic biology; Genetics; Computational biology; Biochemistry; Enzyme","score_opus":0.00881893792826454,"score_gpt":0.27308576782636446,"score_spread":0.2642668298980999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408836821","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32506344,0.02573566,0.33291364,0.25880882,0.011036313,0.0033988599,0.004363822,0.00037753666,0.038301926],"genre_scores_gemma":[0.93514174,0.000742064,0.0029285732,0.050653894,0.002436897,0.00012898816,0.0039814804,0.00010333657,0.0038830144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984391,0.00009994305,0.00041844032,0.000565055,0.000100279794,0.0003772034],"domain_scores_gemma":[0.99901795,0.00005677331,0.00014661052,0.0006523891,0.00008783354,0.00003843517],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010576126,0.00035670286,0.00043830855,0.0001514937,0.000045700668,0.000017479288,0.0004297728,0.0012584163,0.000037144517],"category_scores_gemma":[0.00015082752,0.00032276267,0.00018031546,0.00010755187,0.00025299785,0.0000013831465,0.000103767175,0.0004433407,0.000009975889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028315359,0.00003364415,0.000032323067,0.00011572672,0.00014383499,0.000004350645,0.00006187235,0.0002067642,0.900038,0.00021415885,0.09655639,0.0025645867],"study_design_scores_gemma":[0.00014341027,0.00015570443,0.000029864837,0.000061067716,0.000056078163,0.0000207964,0.000019393225,0.000046866637,0.66606677,0.00007318166,0.33309367,0.0002331734],"about_ca_topic_score_codex":0.00004281388,"about_ca_topic_score_gemma":0.000012085412,"teacher_disagreement_score":0.61007833,"about_ca_system_score_codex":0.000018098539,"about_ca_system_score_gemma":0.00015627574,"threshold_uncertainty_score":0.99992245},"labels":[],"label_agreement":null},{"id":"W4409025649","doi":"10.1093/nar/gkaf235","title":"Efficient DNA- and virus-free engineering of cellular transcriptomic states using dCas9 ribonucleoprotein (dRNP) complexes","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Helmholtz Zentrum München; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; California Department of Fish and Game","keywords":"Biology; Ribonucleoprotein; Cas9; CRISPR; Gene; DNA; Computational biology; Transcriptome; Genome editing; Transcription (linguistics); Genetics; Promoter; Cell biology; RNA; Gene expression","score_opus":0.018149121155371588,"score_gpt":0.3258885689605468,"score_spread":0.3077394478051752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409025649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96998584,0.0026027374,0.026727665,0.000065687105,0.00008026297,0.00027884508,0.000040276896,0.000017079457,0.00020157584],"genre_scores_gemma":[0.9970846,0.0001267727,0.0025475703,0.000013177133,0.00005905715,0.000011167401,0.000015255957,0.000030119681,0.00011227834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866897,0.000056900342,0.00024747598,0.0003447441,0.00026313058,0.00041876928],"domain_scores_gemma":[0.99925,0.00003230693,0.000022184839,0.00047657415,0.00013099036,0.00008796114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005136847,0.00015793109,0.00019972058,0.000221222,0.00010931152,0.000034935005,0.00029014322,0.00013041335,0.00002120939],"category_scores_gemma":[0.000115359646,0.00016425212,0.0000676905,0.0002787908,0.00017344214,0.0000023230352,0.00029769042,0.00020636391,0.0000016898326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000565905,0.00004170269,0.0002661932,0.00018233342,0.00004964691,0.0000029761852,0.00014187241,0.010214042,0.9880254,0.00020839156,0.00018212252,0.00062870915],"study_design_scores_gemma":[0.00058454875,0.00012682527,0.0013265078,0.00008101375,0.000013315349,0.0000033158597,0.00016028249,0.06018883,0.9339389,0.00008167296,0.0033478565,0.00014690512],"about_ca_topic_score_codex":0.00011973291,"about_ca_topic_score_gemma":0.000019154022,"teacher_disagreement_score":0.054086495,"about_ca_system_score_codex":0.000027769074,"about_ca_system_score_gemma":0.000058617487,"threshold_uncertainty_score":0.6698007},"labels":[],"label_agreement":null},{"id":"W4409031076","doi":"10.3389/fgeed.2025.1565297","title":"Cas9 endonuclease: a molecular tool for in vitro cloning and CRISPR edit detection","year":2025,"lang":"en","type":"article","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; University of Calgary; University of Saskatchewan; Saskatchewan Research Council (Canada)","funders":"Saskatchewan Wheat Development Commission; Genome Prairie; Agriculture and Agri-Food Canada; Western Grains Research Foundation; Genome Canada; Alberta Wheat Commission; Ministry of Agriculture - Saskatchewan","keywords":"CRISPR; Endonuclease; Computational biology; Cloning (programming); Cas9; Biology; Genetics; Genome editing; Molecular biology; DNA; Computer science; Gene; Programming language","score_opus":0.0025306707461909407,"score_gpt":0.246183124449879,"score_spread":0.24365245370368807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409031076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5827184,0.004050795,0.41140985,0.00005471439,0.0013326164,0.00026755378,0.0000117952695,0.000010925741,0.00014338852],"genre_scores_gemma":[0.9813061,0.00007779396,0.017800728,0.000080924256,0.00052692095,0.00008235944,0.00003897068,0.000019306339,0.00006690889],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991256,0.000020461064,0.00020986909,0.0003109885,0.00005374989,0.0002793081],"domain_scores_gemma":[0.9997605,0.000013716901,0.000033906206,0.00013565029,0.000025990146,0.000030222847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022971953,0.00012529279,0.0001499518,0.00016828818,0.000051446114,0.000024900795,0.00008091044,0.00012111056,7.7972857e-7],"category_scores_gemma":[0.00019606607,0.00015510542,0.000045579956,0.00013490615,0.00002421124,0.00000461161,0.0000677987,0.00011205829,1.4781054e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069454465,0.0000110175915,0.001377421,0.000079561665,0.000021405327,0.000006898035,0.00007349016,0.001287382,0.9814824,0.0000069123084,0.00032001373,0.015264055],"study_design_scores_gemma":[0.0011672518,0.00006516744,0.002610896,0.000045948895,0.000019922483,0.0000066071934,0.0005362807,0.0055734487,0.96550816,0.00016203031,0.024060316,0.00024399628],"about_ca_topic_score_codex":0.000016617283,"about_ca_topic_score_gemma":0.0000131331935,"teacher_disagreement_score":0.39858773,"about_ca_system_score_codex":0.00004348735,"about_ca_system_score_gemma":0.000023019738,"threshold_uncertainty_score":0.6325015},"labels":[],"label_agreement":null},{"id":"W4409076180","doi":"10.3389/fgeed.2025.1553590","title":"CRISPR-dependent base editing as a therapeutic strategy for rare monogenic disorders","year":2025,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Sick Kids Foundation; Canadian Institutes of Health Research; Institute of Human Development, Child and Youth Health; Hospital for Sick Children; Canada Excellence Research Chairs, Government of Canada; McGill University","keywords":"CRISPR; Genome editing; Computational biology; Computer science; Genetics; Biology; Gene","score_opus":0.015216024991836408,"score_gpt":0.32851389105980844,"score_spread":0.31329786606797205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409076180","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000016510296,0.886306,0.10812711,0.000019048824,0.0034715794,0.0012399346,0.0001939156,0.000029872148,0.0005960645],"genre_scores_gemma":[0.00065875996,0.9894388,0.0033551748,0.00005504538,0.003642367,0.00068537676,0.0010771077,0.00012994865,0.00095743296],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99731266,0.0001033956,0.0007543584,0.0009112146,0.00018258055,0.0007357952],"domain_scores_gemma":[0.9989719,0.000068519184,0.00026658832,0.0005207825,0.00005918082,0.00011302617],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043336436,0.00061086396,0.001048968,0.00032386574,0.00014257597,0.00007498099,0.00053919724,0.00056651107,0.000015793614],"category_scores_gemma":[0.00024176188,0.0006453346,0.0005985613,0.00025820584,0.000045786637,0.0000064578026,0.000189203,0.000408826,0.0000036257206],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016203569,0.000044652246,0.000046244524,0.011197691,0.00040678965,0.000009090917,0.0000638566,0.0013914446,0.00013203752,0.000015394877,0.0032612614,0.9834153],"study_design_scores_gemma":[0.0005625609,0.00016117434,0.000004796937,0.002253574,0.00044090144,0.0000135225455,0.000808772,0.00022964999,0.00018032562,0.0002102359,0.9943791,0.0007554097],"about_ca_topic_score_codex":0.0000133221865,"about_ca_topic_score_gemma":0.000029290357,"teacher_disagreement_score":0.99111784,"about_ca_system_score_codex":0.00011974416,"about_ca_system_score_gemma":0.000379769,"threshold_uncertainty_score":0.9995998},"labels":[],"label_agreement":null},{"id":"W4409119362","doi":"10.1093/hmg/ddaf040","title":"CRISPR-Cas9-driven antigen conversion of clinically relevant blood group systems","year":2025,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec; Héma-Québec","funders":"Centre Hospitalier Universitaire de Québec; Mitacs; Université Laval","keywords":"Biology; CRISPR; Antigen; Genetics; Cas9; Computational biology; Gene","score_opus":0.008114980771581173,"score_gpt":0.31185200580254785,"score_spread":0.30373702503096667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409119362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9162171,0.007167194,0.07442516,0.00002266153,0.0003486522,0.000343796,0.000016971193,0.000023837152,0.0014346453],"genre_scores_gemma":[0.99521977,0.0011082623,0.002983106,0.000121295234,0.00009233971,0.000014878858,0.00010493728,0.00004009088,0.00031532254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982484,0.00008775979,0.0006624309,0.0004773949,0.0002119549,0.00031205502],"domain_scores_gemma":[0.998809,0.000016038663,0.00015366268,0.00076041376,0.00016234069,0.00009858787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022782876,0.00024322022,0.0003064886,0.00010848674,0.0000810617,0.000028505252,0.00038469787,0.0002690184,0.000011236612],"category_scores_gemma":[0.000060045903,0.00026575546,0.0002001408,0.00014290713,0.00011755266,0.000001689039,0.00026258503,0.00013545928,0.0000055374458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002657467,0.000116556155,0.007926636,0.00017734776,0.00020935878,0.000018067845,0.000026092155,0.0034172542,0.9866973,0.00056913437,0.0006652528,0.00015039631],"study_design_scores_gemma":[0.0017013553,0.0009150707,0.011493229,0.00015354488,0.00025695993,0.000022251848,0.00011141561,0.0013743853,0.96114767,0.0001068372,0.022233764,0.0004835171],"about_ca_topic_score_codex":0.00001904575,"about_ca_topic_score_gemma":0.000004623893,"teacher_disagreement_score":0.079002686,"about_ca_system_score_codex":0.000009719381,"about_ca_system_score_gemma":0.00006138409,"threshold_uncertainty_score":0.99997944},"labels":[],"label_agreement":null},{"id":"W4409119410","doi":"10.1139/cjm-2024-0241","title":"Engineering conjugative plasmids for inducible horizontal DNA transfer","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Defense Advanced Research Projects Agency","keywords":"Plasmid; Horizontal gene transfer; Biology; Biotechnology; CRISPR; Gene; Genetics; Bacteria; Antimicrobial; Homologous recombination; Computational biology; Microbiology; Genome","score_opus":0.005066897192157252,"score_gpt":0.2399115372920677,"score_spread":0.23484464009991046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409119410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9477379,0.0016982794,0.04884515,0.00024589355,0.0009906045,0.00012787181,0.00010278148,0.0000023711427,0.00024919183],"genre_scores_gemma":[0.9985011,0.000024599127,0.0008745191,0.00016671486,0.00016146858,0.0000044404405,0.000034489,0.0000115639405,0.00022109339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940246,0.00001261348,0.00020629002,0.00012423517,0.00001111592,0.00024326259],"domain_scores_gemma":[0.99962777,0.0000196039,0.000023333161,0.00009219525,0.00010597933,0.0001311207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013265506,0.000104330386,0.00016119287,0.00015948927,0.000042681415,0.000010228272,0.0001542158,0.00015951574,0.000017560118],"category_scores_gemma":[0.000081397506,0.00010519618,0.00010634694,0.00006357591,0.00004875269,0.0000021444705,0.000007513377,0.00010540803,0.000001154739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028299733,0.000004041528,0.00025544927,0.000016620796,0.00011076691,0.0000047461917,0.00004877397,0.00049038185,0.9938787,0.00029921005,0.004353872,0.00050909066],"study_design_scores_gemma":[0.000651097,0.0002637387,0.00024761737,0.000029463868,0.000025297559,0.000116213254,0.00006373048,0.000017120246,0.7804134,0.000022485443,0.21804437,0.000105498904],"about_ca_topic_score_codex":0.00006601567,"about_ca_topic_score_gemma":0.0020140815,"teacher_disagreement_score":0.2136905,"about_ca_system_score_codex":0.000036232923,"about_ca_system_score_gemma":0.00055123173,"threshold_uncertainty_score":0.42897758},"labels":[],"label_agreement":null},{"id":"W4409162311","doi":"10.1101/2025.04.03.646803","title":"<i>BRCA1</i> is a molecular correlate of cell proliferation in human brain development and in Group 3 and 4 medulloblastoma","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Waterloo; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"Medulloblastoma; Cell growth; Group (periodic table); Human brain; Brain Cell; Brain development; Neuroscience; Psychology; Biology; Cell biology; Cancer research; Physics; Genetics; Quantum mechanics","score_opus":0.004609448887694834,"score_gpt":0.22667258836627516,"score_spread":0.22206313947858033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409162311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993784,0.0025143381,0.0030613178,0.000046852212,0.00009414248,0.0004473363,0.000027768841,0.000013955762,0.000010269694],"genre_scores_gemma":[0.99568975,0.00018661232,0.0038317034,0.00013100635,0.000025757605,0.0000958049,0.0000013799485,0.000029728522,0.000008246175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855477,0.00005240234,0.00042731428,0.0006072649,0.0001191225,0.00023915168],"domain_scores_gemma":[0.9993713,0.0000102530785,0.00011939112,0.00035868832,0.000063031235,0.000077356395],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003166728,0.00028936483,0.0003083798,0.00022782126,0.00002999338,0.000031635496,0.00014247607,0.00038912115,0.0000015383748],"category_scores_gemma":[0.00003810618,0.00034994676,0.00003512994,0.00017112175,0.00004953244,0.000004179584,0.00036921914,0.00025968454,2.765651e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025361973,0.00006435313,0.0133107,0.00054114347,0.000029265699,0.000010753724,0.000042205153,0.00023341752,0.9856744,0.000035702684,0.000026816011,0.000005890832],"study_design_scores_gemma":[0.0007011161,0.0000497642,0.06774516,0.0003137925,0.00001540291,2.1284604e-8,0.000004320708,0.00033400598,0.92981654,0.000001378707,0.000698659,0.0003198498],"about_ca_topic_score_codex":0.000023278784,"about_ca_topic_score_gemma":0.000041467414,"teacher_disagreement_score":0.055857856,"about_ca_system_score_codex":0.00003843867,"about_ca_system_score_gemma":0.00017233258,"threshold_uncertainty_score":0.9998953},"labels":[],"label_agreement":null},{"id":"W4409230667","doi":"10.1002/pld3.70070","title":"Establishing an Immune System Conferring DNA and RNA Virus Resistance in Plants Using CRISPR/Cas12a Multiplex Gene Editing","year":2025,"lang":"en","type":"article","venue":"Plant Direct","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Central Public Research Institutes Basic Funds for Research and Development; China Agricultural University; Institute of Genetics; Shandong Agricultural University; National Natural Science Foundation of China","keywords":"Nicotiana benthamiana; CRISPR; Biology; Guide RNA; Gene; Genome editing; Virus; Virology; RNA; Transgene; Multiplex; Genetics; Molecular biology","score_opus":0.011932949064443789,"score_gpt":0.2785862030514162,"score_spread":0.26665325398697237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409230667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873488,0.006915643,0.0031389168,0.000009389817,0.0004603814,0.00016123691,0.00013290401,0.000041813186,0.001790903],"genre_scores_gemma":[0.9977461,0.000196419,0.0016076273,0.000022199665,0.00021376814,0.000010952591,0.00011859718,0.000021029957,0.000063294676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988376,0.000057638226,0.0002893754,0.0003997997,0.00009383346,0.00032173583],"domain_scores_gemma":[0.99955595,0.000045302982,0.00006196795,0.000246794,0.00002511346,0.00006490229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003174244,0.00018611648,0.00024374088,0.000115665585,0.000110201654,0.00008179745,0.00014223107,0.00012170321,0.000001089137],"category_scores_gemma":[0.000106000254,0.00020266356,0.000034288627,0.000091444526,0.00002305945,0.00001255252,0.00010529231,0.000115444614,3.6474395e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007343543,0.000016172153,0.0022521948,0.00015778432,0.000031768446,0.000043162137,0.00015364037,0.0011951525,0.995454,0.000028978227,0.000043726614,0.0005499857],"study_design_scores_gemma":[0.0005799215,0.000019058127,0.0055189617,0.0004712491,0.000019108411,0.000030139641,0.00039738626,0.012157133,0.9786296,0.0000042088477,0.0019237318,0.00024951843],"about_ca_topic_score_codex":0.00046980928,"about_ca_topic_score_gemma":0.0012642314,"teacher_disagreement_score":0.016824415,"about_ca_system_score_codex":0.000038638096,"about_ca_system_score_gemma":0.000037498226,"threshold_uncertainty_score":0.826438},"labels":[],"label_agreement":null},{"id":"W4409256306","doi":"10.1007/978-1-0716-4378-5_20","title":"A Protocol for High-efficiency Transformation and Genome Editing in Elite Wheat Cultivars","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Elite; Transformation (genetics); Protocol (science); Cultivar; Biology; Genome; Computer science; Horticulture; Genetics; Political science; Gene; Medicine","score_opus":0.013457261853983426,"score_gpt":0.4391677847487099,"score_spread":0.42571052289472644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409256306","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023759468,0.0002145085,0.9580768,0.000115856936,0.00007471253,0.01739602,0.000006573008,0.000008165504,0.0003479399],"genre_scores_gemma":[0.049700815,0.000031566782,0.86592615,0.0004304583,0.00008223828,0.0836705,0.00007350321,0.000027276365,0.000057486715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988762,0.0001994792,0.00030526015,0.00032839147,0.000026994081,0.00026364045],"domain_scores_gemma":[0.99971294,0.000037496455,0.000033615444,0.00015977131,0.000030445644,0.000025756823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074317766,0.00014037028,0.00018587912,0.00017124397,0.000029190225,0.000010176589,0.00010969967,0.00020042455,0.0000020494404],"category_scores_gemma":[0.00020586631,0.00013750145,0.000043852575,0.0001759482,0.000050509712,0.0000023725204,0.000054482134,0.00009581582,1.4468793e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049986986,0.000027608801,0.0004065247,0.00010277766,0.000009620397,8.6189914e-7,0.00007918788,0.0006942288,0.97643876,0.0017240533,0.000002851809,0.020463554],"study_design_scores_gemma":[0.0027660942,0.00024281756,0.0030548954,0.000072753115,0.000010193242,0.00000551,0.00010768464,0.0024232108,0.9619691,0.0039527733,0.025132595,0.00026239446],"about_ca_topic_score_codex":0.000019284576,"about_ca_topic_score_gemma":0.000019759013,"teacher_disagreement_score":0.09215059,"about_ca_system_score_codex":0.000018494677,"about_ca_system_score_gemma":0.00003062753,"threshold_uncertainty_score":0.56071466},"labels":[],"label_agreement":null},{"id":"W4409289706","doi":"10.1101/2025.04.09.648054","title":"RAPID-DASH: Fast and Efficient Assembly of Guide RNA Arrays for Multiplexed CRISPR-Cas9 Applications","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Genome British Columbia","funders":"National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC","keywords":"CRISPR; Guide RNA; Computer science; Multiplexing; Computational biology; Dash; Scalability; Cas9; RNA; Biology; Genetics; Telecommunications; Operating system","score_opus":0.009924925676264415,"score_gpt":0.2689512308597322,"score_spread":0.2590263051834678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409289706","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3032352,0.007692848,0.6845135,0.00011579158,0.0006803336,0.0023562578,0.0012364596,0.000109392786,0.00006019589],"genre_scores_gemma":[0.9605515,0.0007139979,0.037352838,0.00007114052,0.00037499712,0.00082768546,0.000005006165,0.00007074,0.000032116972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980001,0.000038280596,0.0005374051,0.0008818141,0.00016104162,0.0003813725],"domain_scores_gemma":[0.9980005,0.00004910786,0.0002461595,0.0010771542,0.00046567016,0.00016138495],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003547084,0.0004238634,0.00044822032,0.00016537093,0.00010812967,0.000053015574,0.00040021827,0.000476359,0.0000034775674],"category_scores_gemma":[0.00018356666,0.00048225877,0.00019277201,0.00018247786,0.00009379877,0.0000026313014,0.00045077057,0.00021602752,0.0000014893828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028936729,0.00009763314,0.00017101952,0.0007405336,0.00016013267,7.045297e-7,0.0000062298827,0.0038052045,0.9942423,0.00017889912,0.0005219452,0.000046452373],"study_design_scores_gemma":[0.00062186806,0.00006892448,0.002396992,0.00014911054,0.00013117421,1.5152457e-8,0.000006803751,0.0035506745,0.9568319,6.614065e-7,0.035777017,0.00046486812],"about_ca_topic_score_codex":0.000017989443,"about_ca_topic_score_gemma":0.0000028569161,"teacher_disagreement_score":0.65731627,"about_ca_system_score_codex":0.000041542247,"about_ca_system_score_gemma":0.0003127789,"threshold_uncertainty_score":0.9997629},"labels":[],"label_agreement":null},{"id":"W4409316759","doi":"10.1016/j.ijbiomac.2025.142999","title":"Emerging wound-healing injectable polydeoxyribonucleotide: potential as a prohibited doping method and its simple detection via CRISPR/Cas12a system","year":2025,"lang":"en","type":"article","venue":"International Journal of Biological Macromolecules","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Korea Institute of Science and Technology; World Anti-Doping Agency","keywords":"CRISPR; Wound healing; Simple (philosophy); Chemistry; Biology; Gene; Genetics; Biochemistry","score_opus":0.007462944081010629,"score_gpt":0.3269126758046505,"score_spread":0.3194497317236399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409316759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.57728344,0.0015184064,0.42036766,0.00017596722,0.00043681051,0.00008409768,0.0000059140584,0.000013072718,0.00011463201],"genre_scores_gemma":[0.99640393,0.00020972402,0.0028158538,0.00018609114,0.00032292632,0.000005451234,0.000014694168,0.0000119977285,0.000029322346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987756,0.00010792503,0.00046516093,0.00025598216,0.00018441367,0.00021093324],"domain_scores_gemma":[0.9992517,0.00003459852,0.00019906323,0.000086606284,0.00034907908,0.000078901605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003716678,0.000167818,0.00021314918,0.00018543554,0.00009188014,0.00007958139,0.00025178533,0.00015982943,0.000009170342],"category_scores_gemma":[0.00024951817,0.00014211178,0.00013717217,0.00011640705,0.000029278382,0.000011388404,0.0001849604,0.00018567304,0.0000016807238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022146928,0.000029917177,0.00038295722,0.000030432382,0.00021031845,0.00006517642,0.000020736936,0.0014807244,0.98277676,0.00025999092,0.00001708947,0.014504442],"study_design_scores_gemma":[0.00081200385,0.00039569233,0.0021516029,0.00014630157,0.000048177782,0.0013787753,0.00025840316,0.007725003,0.9846026,0.00056173577,0.0017078577,0.00021189317],"about_ca_topic_score_codex":0.000031904106,"about_ca_topic_score_gemma":0.0000054263123,"teacher_disagreement_score":0.4191205,"about_ca_system_score_codex":0.000047185673,"about_ca_system_score_gemma":0.000041698117,"threshold_uncertainty_score":0.57951504},"labels":[],"label_agreement":null},{"id":"W4409365773","doi":"10.2147/dnnd.s495536","title":"Gene Editing for Duchenne Muscular Dystrophy: From Experimental Models to Emerging Therapies","year":2025,"lang":"en","type":"review","venue":"Degenerative Neurological and Neuromuscular Disease","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"","keywords":"Duchenne muscular dystrophy; Genome editing; Muscular dystrophy; Medicine; Computer science; Computational biology; Gene; Biology; CRISPR; Genetics; Internal medicine","score_opus":0.031093457627698287,"score_gpt":0.33194634593768285,"score_spread":0.3008528883099846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409365773","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030466331,0.95100415,0.015816119,0.00011235062,0.0004049305,0.0013520196,0.0007932438,0.00004161737,0.000009259749],"genre_scores_gemma":[0.008572847,0.984258,0.0021366256,0.000981334,0.0013524129,0.001290347,0.0011865052,0.00009910712,0.00012284677],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973239,0.00024500286,0.00043118477,0.0013740688,0.0001763767,0.00044950697],"domain_scores_gemma":[0.9988356,0.0000788827,0.00009301048,0.0005073123,0.000070033806,0.0004151129],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009120735,0.00068430975,0.0009029832,0.00010571076,0.00022063481,0.00008742312,0.00031891064,0.00024447715,0.00001306336],"category_scores_gemma":[0.00016987039,0.00055905135,0.00069246173,0.0001362036,0.00006941044,0.000007746588,0.00040004653,0.0002049202,0.0000023182986],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011897152,0.0012420996,0.00004288654,0.009894799,0.002507398,0.00064388814,0.00034043944,0.017275346,0.1235574,0.0009713546,0.0044753347,0.83785933],"study_design_scores_gemma":[0.0007901982,0.0009881951,0.00005400549,0.00071968953,0.0011339547,0.000011791034,0.000020824902,0.0017022821,0.007285572,0.00016187668,0.98585427,0.0012773159],"about_ca_topic_score_codex":0.0000044562157,"about_ca_topic_score_gemma":0.0000014791337,"teacher_disagreement_score":0.981379,"about_ca_system_score_codex":0.000009026277,"about_ca_system_score_gemma":0.000074749085,"threshold_uncertainty_score":0.9996861},"labels":[],"label_agreement":null},{"id":"W4409423211","doi":"10.1016/j.gendis.2025.101636","title":"A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo","year":2025,"lang":"en","type":"article","venue":"Genes & Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Fluorophore; DNA; CRISPR; Computational biology; Cas9; Computer science; Molecular biology; Biology; Genetics; Fluorescence; Physics; Gene","score_opus":0.011324345342999271,"score_gpt":0.3336307270506432,"score_spread":0.322306381707644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409423211","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2773976,0.016506415,0.7055816,0.000028439441,0.00019328453,0.00021477944,0.000059097125,0.0000078372605,0.000010942438],"genre_scores_gemma":[0.9877078,0.00027562276,0.011573543,0.00007729979,0.0001612488,0.000063417996,0.00001855979,0.000015198995,0.000107340464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945974,0.000015378784,0.00013947327,0.00018643995,0.000055659086,0.0001432772],"domain_scores_gemma":[0.99956584,0.00004134706,0.000038219012,0.00024553324,0.00007545035,0.000033614127],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000068037865,0.00010391636,0.00011071505,0.000035784873,0.00008492733,0.000011603753,0.00011512591,0.000055099816,0.0000023604318],"category_scores_gemma":[0.00007672856,0.00008340712,0.00012701427,0.00010271226,0.000028176757,0.0000013043043,0.000061666426,0.00002087236,1.8278679e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007926922,0.000033398912,0.00019515,0.00006372857,0.000103617196,1.7410129e-7,0.000012161317,0.0031288934,0.96484,0.000021438731,0.00004276022,0.031479426],"study_design_scores_gemma":[0.00043312475,0.000056337587,0.0018518113,0.000015213476,0.00022314339,0.0000052350465,0.00007733272,0.009558973,0.97858375,0.000039877596,0.009058345,0.00009684105],"about_ca_topic_score_codex":0.000065192195,"about_ca_topic_score_gemma":0.0000414863,"teacher_disagreement_score":0.71031016,"about_ca_system_score_codex":0.0000088005345,"about_ca_system_score_gemma":0.00006370481,"threshold_uncertainty_score":0.34012434},"labels":[],"label_agreement":null},{"id":"W4409505626","doi":"10.1038/s41568-025-00818-7","title":"CRISPR-StAR to transform in vivo functional genomic screening","year":2025,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Star (game theory); CRISPR; In vivo; Computational biology; Biology; Genetics; Physics; Gene; Astrophysics","score_opus":0.018881072614750867,"score_gpt":0.3834130253945681,"score_spread":0.36453195277981726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409505626","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000024302703,0.9923361,0.004182006,0.000069293565,0.0007510325,0.0014249076,0.00018893219,0.000012168817,0.0010331549],"genre_scores_gemma":[0.00000721818,0.99445176,0.0010938791,0.000551064,0.00081012957,0.0007319492,0.00020010203,0.000055662982,0.0020982097],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99807143,0.00007204621,0.0006374335,0.0006936797,0.0001485815,0.0003767993],"domain_scores_gemma":[0.99924177,0.000025595624,0.000106233485,0.00045681678,0.00005489915,0.00011470521],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030756718,0.0005073971,0.001300605,0.0002132595,0.00004240101,0.000023586126,0.00033738752,0.00087487756,0.00017371449],"category_scores_gemma":[0.00010027433,0.0004318651,0.0006338857,0.00045588694,0.000014869484,0.0000028479285,0.00009869195,0.0007778785,0.000014911412],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010455943,0.00001093334,0.0000027797087,0.013889055,0.000083743515,0.0000023585133,0.000007402686,0.000083694125,0.00024649673,0.000011969411,0.02256374,0.9630874],"study_design_scores_gemma":[0.0001443488,0.000025868656,0.000009588842,0.013377249,0.00025422263,0.000008045883,0.0000019218287,0.000001993092,0.00021416131,0.0000025602492,0.98553675,0.00042326143],"about_ca_topic_score_codex":0.00001980368,"about_ca_topic_score_gemma":0.00028595372,"teacher_disagreement_score":0.96297306,"about_ca_system_score_codex":0.00011848342,"about_ca_system_score_gemma":0.00034238526,"threshold_uncertainty_score":0.9998133},"labels":[],"label_agreement":null},{"id":"W4409514461","doi":"10.1152/ajpheart.00122.2025","title":"Mlc2v-Cre induces germline recombination in a sex-biased manner","year":2025,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Institute of Circulatory and Respiratory Health; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Canadian Institutes of Health Research; Government of Ontario; University of Ottawa Heart Institute Foundation; Heart and Stroke Foundation of Canada","keywords":"Germline; Biology; Transgene; Offspring; Gene isoform; Allele; Genetics; Genetically modified mouse; Molecular biology; Gene; Cell biology","score_opus":0.0061964621446358534,"score_gpt":0.277049170628303,"score_spread":0.2708527084836671,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409514461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983022,0.0010042823,0.000037476468,0.00022770863,0.00027503318,0.00008112903,0.000002654221,0.0000058436485,0.00006366749],"genre_scores_gemma":[0.99863344,0.0002077372,0.00019705677,0.00067093235,0.00019805887,0.000006919424,0.000016417782,0.000013573093,0.000055851884],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99882114,0.00015441868,0.0003852922,0.00032047165,0.000063194595,0.00025548835],"domain_scores_gemma":[0.9993915,0.000042476175,0.00018094917,0.00022642566,0.000090214184,0.00006845366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022991614,0.00017864772,0.00045043818,0.00019428963,0.00005072038,0.0000065051063,0.00015193579,0.00012477071,0.000012260781],"category_scores_gemma":[0.0000489766,0.00016616077,0.0001199656,0.00019938401,0.00027371713,0.000008550983,0.00006718425,0.0002421041,0.000001643406],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010037195,0.000079323996,0.0017009239,0.00002318104,0.00007851196,3.2750924e-7,0.00006365804,0.0006037662,0.9953797,0.00006164357,0.00032354993,0.0015850762],"study_design_scores_gemma":[0.0010062376,0.0007006494,0.9237534,0.000044555258,0.00002967728,0.000038234306,0.0003671472,0.00014723893,0.06915992,0.000989056,0.0035515046,0.000212422],"about_ca_topic_score_codex":0.000017112636,"about_ca_topic_score_gemma":0.0000059742392,"teacher_disagreement_score":0.92621976,"about_ca_system_score_codex":0.000018552051,"about_ca_system_score_gemma":0.00009103833,"threshold_uncertainty_score":0.67758393},"labels":[],"label_agreement":null},{"id":"W4409640727","doi":"10.1039/d4cb00230j","title":"Monitoring SARS-CoV-2 Nsp13 helicase binding activity using expanded genetic code techniques","year":2025,"lang":"en","type":"article","venue":"RSC Chemical Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Helicase; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Biology; Genetics; Virology; Computational biology; Medicine; Gene; Internal medicine; RNA","score_opus":0.0238766038000971,"score_gpt":0.3859151778626162,"score_spread":0.3620385740625191,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409640727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9680613,0.0008290866,0.03026477,0.000057335183,0.00024475303,0.00016369393,0.00001863234,0.00007149615,0.0002888769],"genre_scores_gemma":[0.98971593,0.00021240127,0.009541743,0.0000845425,0.00031841113,0.00003202916,0.000023309929,0.000023264967,0.000048374084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877125,0.000039626233,0.00022753264,0.000507076,0.00005422002,0.0004003043],"domain_scores_gemma":[0.99944466,0.000027714792,0.000052948082,0.00037247405,0.000048326965,0.000053883552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000094998664,0.00023275997,0.00024723023,0.00008486311,0.00007065087,0.0000185802,0.00023176815,0.00038749838,0.0000035400426],"category_scores_gemma":[0.00009987959,0.00023728299,0.00011477974,0.00015895814,0.00010375454,0.0000028420006,0.00025553466,0.00017642541,0.0000039304873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004364451,0.00003926236,0.003257542,0.000028135995,0.000047236754,0.0000033175309,0.000007541541,0.00000794811,0.9823053,0.000009857684,0.00008367307,0.014166578],"study_design_scores_gemma":[0.00027902517,0.000053893116,0.00024123998,0.000042359763,0.000026568383,0.000026446713,0.000009829629,0.00021561155,0.99437857,0.00006814913,0.00441897,0.00023933938],"about_ca_topic_score_codex":0.000033429,"about_ca_topic_score_gemma":0.0000035068808,"teacher_disagreement_score":0.021654569,"about_ca_system_score_codex":0.000050513445,"about_ca_system_score_gemma":0.00005226658,"threshold_uncertainty_score":0.96761197},"labels":[],"label_agreement":null},{"id":"W4409672564","doi":"10.1016/b978-0-443-29068-8.00133-1","title":"Studying the genetics of behavior in the genomics era","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Genomics; Genetics; Biology; Computational biology; Evolutionary biology; Genome; Gene","score_opus":0.012524502634483372,"score_gpt":0.27840966408049594,"score_spread":0.2658851614460126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409672564","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018368931,0.01655182,0.0000963815,0.000064620115,0.00036617278,0.0011630172,0.000055862285,0.0000069280673,0.9633263],"genre_scores_gemma":[0.15049888,0.0021632938,0.0005673852,0.00049835467,0.0005254768,0.00014699422,0.000071255425,0.00008501641,0.84544337],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99905384,0.000026709435,0.00033877217,0.00026071921,0.00014715483,0.00017279468],"domain_scores_gemma":[0.9990934,0.00002904928,0.00009820406,0.0007103746,0.00004787517,0.000021076072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025100078,0.00023864284,0.00022542263,0.000053713356,0.00005261606,0.000017957911,0.0005171473,0.00022417528,0.000008056877],"category_scores_gemma":[0.000012107015,0.00016333247,0.00016984153,0.00001266122,0.00009069769,3.635185e-7,0.00019693423,0.0003028191,0.0000020549405],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013803307,0.00001695389,0.00010217335,0.00007225038,0.000095426934,0.000008118096,0.00037133266,0.00008960635,0.013628344,0.00046280836,0.00019929468,0.9849399],"study_design_scores_gemma":[0.00021937815,0.00010894563,0.00055605255,0.00007654316,0.00018569204,0.000012082964,0.000078352765,0.0000129729115,0.0074124453,0.00022212605,0.99086547,0.00024991023],"about_ca_topic_score_codex":7.993918e-7,"about_ca_topic_score_gemma":0.00006144691,"teacher_disagreement_score":0.9906662,"about_ca_system_score_codex":0.000015129539,"about_ca_system_score_gemma":0.000104284874,"threshold_uncertainty_score":0.6660505},"labels":[],"label_agreement":null},{"id":"W4409712505","doi":"10.1101/2025.04.16.649101","title":"Improved CRISPR/Cas9 Off-target Prediction with DNABERT and Epigenetic Features","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; University of Tokyo","keywords":"CRISPR; Epigenetics; Computational biology; Computer science; Cas9; Genetics; Biology; Gene","score_opus":0.0040253486039113495,"score_gpt":0.22356942607297536,"score_spread":0.21954407746906401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409712505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9165641,0.027315088,0.05199379,0.0002669974,0.0013810195,0.0013855258,0.0007790948,0.00025446582,0.000059929094],"genre_scores_gemma":[0.9866587,0.0020226317,0.010212281,0.00016151826,0.00053860113,0.00021362891,0.000004907379,0.00009414977,0.00009359836],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978207,0.00005900256,0.00033877074,0.001108751,0.00019206284,0.00048072686],"domain_scores_gemma":[0.9982789,0.000015732774,0.00015257097,0.0010592267,0.0002734619,0.00022009952],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022088616,0.0005751185,0.00041226603,0.00015608221,0.00012872442,0.00013672629,0.00032164544,0.00066939497,0.000007809599],"category_scores_gemma":[0.00009336493,0.00057296635,0.0001069524,0.00017769304,0.000106584266,0.000006761988,0.00048356544,0.00047739036,0.0000015600053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009304176,0.00006147776,0.0051801917,0.0004625993,0.00030737527,0.000010146338,0.000008159808,0.00081981666,0.9920201,0.000024081817,0.000993209,0.000019839603],"study_design_scores_gemma":[0.00071303046,0.00024541878,0.07222354,0.00025068177,0.00018913281,1.336539e-7,0.000004320394,0.00090630515,0.90782005,0.0000011778608,0.016939081,0.00070711016],"about_ca_topic_score_codex":0.000037221227,"about_ca_topic_score_gemma":0.000011951701,"teacher_disagreement_score":0.084199995,"about_ca_system_score_codex":0.00004897189,"about_ca_system_score_gemma":0.00036573605,"threshold_uncertainty_score":0.9996722},"labels":[],"label_agreement":null},{"id":"W4409727666","doi":"10.1101/2025.04.16.649183","title":"ChromeCRISPR - A High Efficacy Hybrid Machine Learning Model for CRISPR/Cas On-Target Predictions","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Alliance de recherche numérique du Canada","keywords":"CRISPR; Computer science; Artificial intelligence; Computational biology; Machine learning; Biology; Genetics","score_opus":0.009870080416592963,"score_gpt":0.261146004161246,"score_spread":0.251275923744653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409727666","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19795395,0.0026368306,0.7913339,0.00028763883,0.0015273304,0.0015873729,0.0042490163,0.00039743862,0.000026479198],"genre_scores_gemma":[0.9807848,0.0006408554,0.01658725,0.00021946161,0.00081208727,0.00056430645,0.000031510874,0.00016283298,0.00019693219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99708927,0.000059469952,0.0005449257,0.0013529543,0.0002666548,0.00068670185],"domain_scores_gemma":[0.9977689,0.00008310393,0.00022124888,0.0012991836,0.00036097653,0.00026659734],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000358701,0.0007245629,0.0005726914,0.00026755204,0.00029531252,0.00012200267,0.0005910507,0.0005609796,0.000016725946],"category_scores_gemma":[0.000661312,0.00082981266,0.00036168168,0.00019025081,0.00007218706,0.000006605761,0.00055587053,0.0008155211,0.0000107443375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000140398,0.00037576712,0.0007205078,0.0006142744,0.00044587444,0.000011024498,0.000011205337,0.31889868,0.6743612,0.00019229304,0.0042223134,0.0000064214446],"study_design_scores_gemma":[0.0012561751,0.00029864672,0.002196431,0.00025529772,0.00021284523,4.6916536e-8,0.0000012103411,0.24756835,0.7288798,0.000005527663,0.018408304,0.00091736653],"about_ca_topic_score_codex":0.000026840366,"about_ca_topic_score_gemma":0.0000030214856,"teacher_disagreement_score":0.78283083,"about_ca_system_score_codex":0.00012548637,"about_ca_system_score_gemma":0.00052089774,"threshold_uncertainty_score":0.9994153},"labels":[],"label_agreement":null},{"id":"W4409813986","doi":"10.1093/nar/gkaf346","title":"The N=1 Collaborative: advancing customized nucleic acid therapies through collaboration and data sharing","year":2025,"lang":"en","type":"review","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Leids Universitair Medisch Centrum","keywords":"Biology; Therapeutic modalities; Data sharing; Personalized medicine; Engineering ethics; Modalities; Genome editing; Oligonucleotide; Biotechnology; Computational biology; Knowledge management; Bioinformatics; CRISPR; Computer science; Medicine; Gene; Genetics; Engineering; Alternative medicine; Internal medicine","score_opus":0.0539214523154553,"score_gpt":0.4600599526880875,"score_spread":0.4061385003726322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409813986","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010618139,0.9951596,0.00071921595,0.00019521573,0.000247259,0.0012404379,0.00020720228,0.0000296851,0.0020951487],"genre_scores_gemma":[0.0002977233,0.99530953,0.0016523853,0.000022079616,0.0003628116,0.00018854278,0.0005130367,0.00008058362,0.0015733127],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967504,0.00046875328,0.0005124269,0.0011457178,0.00045274608,0.0006699498],"domain_scores_gemma":[0.9969052,0.000320282,0.00012379586,0.002127562,0.0004220794,0.000101101854],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022196982,0.00040288593,0.0007276027,0.00013863182,0.0007957537,0.00048726593,0.0018073075,0.0004334468,0.000017350781],"category_scores_gemma":[0.001292547,0.0002939064,0.0000991595,0.0010352816,0.00031285756,0.000023988789,0.0025282337,0.0006531608,0.000015621406],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111405825,0.000037611273,0.000012442259,0.0053453837,0.0005180281,0.000007681373,0.0003908821,0.000008944788,0.0043882965,0.00055038364,0.020438973,0.96818995],"study_design_scores_gemma":[0.00039073557,0.000088642955,0.0000027183937,0.0015061016,0.00009517894,0.000007912343,0.0009966516,0.00011294981,0.0004795812,0.00008166748,0.99594694,0.00029090978],"about_ca_topic_score_codex":0.00001236773,"about_ca_topic_score_gemma":0.00010126265,"teacher_disagreement_score":0.975508,"about_ca_system_score_codex":0.00008134373,"about_ca_system_score_gemma":0.00083415955,"threshold_uncertainty_score":0.9999513},"labels":[],"label_agreement":null},{"id":"W4409825247","doi":"10.3389/fgene.2025.1566291","title":"Emerging and evolving values in the changing landscape of genomics","year":2025,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre","funders":"","keywords":"Genomics; Sustainability; Accountability; Mainstreaming; Scarcity; Health care; Corporate governance; Equity (law); Context (archaeology); Engineering ethics; Political science; Mainstream; Business; Public relations; Biology; Engineering; Law; Economics; Genetics; Ecology","score_opus":0.003255465886409003,"score_gpt":0.25317980139891144,"score_spread":0.24992433551250243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409825247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92400354,0.028638188,0.046235133,0.000076887496,0.00027880073,0.00012510894,0.0000025397255,0.000002583552,0.0006372147],"genre_scores_gemma":[0.9876555,0.0022258726,0.009902569,0.000072193085,0.00004615462,0.000007471775,0.000006966783,0.000008148884,0.000075078045],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994261,0.000027628668,0.00016482799,0.00015358308,0.000053022544,0.00017479072],"domain_scores_gemma":[0.99975336,0.000009621094,0.000024805497,0.00018386205,0.000015698193,0.000012637464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002481867,0.00008372876,0.00011001763,0.00017217374,0.000025591262,0.000011065907,0.00014621526,0.00006696364,8.834196e-7],"category_scores_gemma":[0.000033368764,0.00007739151,0.000025131772,0.00020156494,0.000033479286,0.0000012654265,0.000086319626,0.0000662763,5.808542e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044614848,0.0000632388,0.8103104,0.00022502644,0.00007758643,0.0000056372965,0.005858109,0.026604276,0.109007165,0.00009603071,0.0050847474,0.04262314],"study_design_scores_gemma":[0.0034078236,0.00032699807,0.4124373,0.00038406486,0.00012525686,0.000018896098,0.03744645,0.17541605,0.32946447,0.0028952102,0.03706397,0.0010135123],"about_ca_topic_score_codex":0.0000039862202,"about_ca_topic_score_gemma":0.000015595739,"teacher_disagreement_score":0.39787313,"about_ca_system_score_codex":0.000007986374,"about_ca_system_score_gemma":0.0000229137,"threshold_uncertainty_score":0.31559342},"labels":[],"label_agreement":null},{"id":"W4409911744","doi":"10.1016/j.ymeth.2025.04.018","title":"CRISPR revolution: Unleashing precision pathogen detection to safeguard public health and food safety","year":2025,"lang":"en","type":"review","venue":"Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"FPInnovations","funders":"","keywords":"Safeguard; CRISPR; Food safety; Pathogen; Public health; Foodborne pathogen; Virology; Business; Biology; Environmental health; Internet privacy; Microbiology; Medicine; Computer science; Gene; Genetics; International trade","score_opus":0.05354551946490936,"score_gpt":0.451449348742867,"score_spread":0.39790382927795764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409911744","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000018105524,0.52337515,0.47564542,0.00005493451,0.00031116122,0.00041661324,0.00003349361,0.000017446308,0.00014398772],"genre_scores_gemma":[0.000011111047,0.88041216,0.11851263,0.00010286365,0.00030030592,0.00009314992,0.00014780373,0.000039856386,0.00038012743],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99735355,0.0008823543,0.000566607,0.0006979199,0.00012403993,0.00037553447],"domain_scores_gemma":[0.9988093,0.000118022544,0.00014305663,0.00057304755,0.00007030265,0.00028627057],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020103408,0.00035511263,0.00084021006,0.0002139621,0.0001659219,0.00005375269,0.00022377899,0.00038834588,0.000005342059],"category_scores_gemma":[0.0010905858,0.0003334709,0.0002587075,0.00038635088,0.000018856332,0.0000035448936,0.00034555685,0.0002455193,0.0000028242068],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005599244,0.000010449528,8.417063e-7,0.004105379,0.00006447773,2.5074993e-7,0.00003073459,0.000008248817,0.0004145488,0.000017462855,0.00025285204,0.9950892],"study_design_scores_gemma":[0.000100176396,0.00033932537,0.000011561061,0.0014810006,0.000076123964,0.000031171243,0.000022777534,0.000013406974,0.00030948716,0.000020468526,0.99730074,0.00029373082],"about_ca_topic_score_codex":0.0000055376786,"about_ca_topic_score_gemma":0.000019873578,"teacher_disagreement_score":0.9970479,"about_ca_system_score_codex":0.00010181586,"about_ca_system_score_gemma":0.0003674123,"threshold_uncertainty_score":0.9999117},"labels":[],"label_agreement":null},{"id":"W4409963753","doi":"10.1021/acs.analchem.5c00256","title":"Accelerating Cleavage Activity of CRISPR-Cas13 System on a Microfluidic Chip for Rapid Detection of RNA","year":2025,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"York University; Trường Đại học Bách Khoa Hà Nội; New York University Abu Dhabi","keywords":"Chemistry; Microfluidic chip; CRISPR; Chip; RNA; Cleavage (geology); Microfluidics; Nanotechnology; Biochemistry; Gene; Telecommunications","score_opus":0.011809755268179208,"score_gpt":0.29770713338866817,"score_spread":0.28589737812048893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409963753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9366046,0.0005603217,0.058205914,0.00002832741,0.00005700247,0.0001253778,0.00002153184,0.00001157517,0.0043853237],"genre_scores_gemma":[0.9994353,0.0000403683,0.00013047043,0.000016235199,0.00009262467,0.000014015614,0.000013296045,0.000011395189,0.00024629704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927044,0.000011326228,0.000237202,0.00024543144,0.00007829029,0.00015731355],"domain_scores_gemma":[0.99950206,0.000041178817,0.00006919059,0.00027336762,0.00007161412,0.000042604926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001304568,0.00012412346,0.00021075408,0.000026959735,0.00003540795,0.000007191159,0.00011425874,0.00016340349,0.000004308504],"category_scores_gemma":[0.00014906656,0.0001261141,0.00015953903,0.00010296316,0.000043375137,0.0000016280446,0.000046083933,0.00008547396,3.565857e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014084304,0.00004877119,0.00005974601,0.0007728163,0.000085101936,3.76427e-7,0.000005217582,0.000044946537,0.9948454,0.000030528205,0.00030614343,0.0036601073],"study_design_scores_gemma":[0.0004008171,0.00010185825,0.0003395198,0.00008576682,0.0000628341,0.000002048592,0.000057992074,0.0024486177,0.9958227,0.000005449955,0.0005758408,0.000096541604],"about_ca_topic_score_codex":0.000007784748,"about_ca_topic_score_gemma":7.404466e-7,"teacher_disagreement_score":0.06283067,"about_ca_system_score_codex":0.00002096581,"about_ca_system_score_gemma":0.00003917823,"threshold_uncertainty_score":0.5142784},"labels":[],"label_agreement":null},{"id":"W4409980955","doi":"10.1016/j.jcyt.2025.03.180","title":"GENOME EDITING WITH THE DNA-PK INHIBITOR AZD7648 INDUCES A LOW FREQUENCY OF COPY NUMBER VARIATIONS IN HEMATOPOIETIC STEM AND PROGENITORS CELLS","year":2025,"lang":"en","type":"article","venue":"Cytotherapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Terry Fox Research Institute; Institute for Research in Immunology and Cancer","funders":"","keywords":"Genome editing; Haematopoiesis; Biology; Stem cell; Progenitor cell; Genome; DNA; Genetics; Computational biology; Cell biology; Gene","score_opus":0.004062521117845436,"score_gpt":0.2505574513865805,"score_spread":0.24649493026873504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409980955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944126,0.000726751,0.004117482,0.00015168925,0.00008741517,0.0002422124,0.0000076021383,0.0000068450445,0.00024741114],"genre_scores_gemma":[0.99896455,0.00010501068,0.000572595,0.00006755922,0.00012057669,0.00004381909,0.000005210609,0.000014111254,0.00010654983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994445,0.000026363896,0.00015434815,0.0001756221,0.00006516105,0.00013399313],"domain_scores_gemma":[0.9996988,0.00001743593,0.000048060196,0.00017435267,0.000038150178,0.00002318604],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010089399,0.00010694612,0.00011686184,0.000037790043,0.000043001273,0.000017355433,0.00009320948,0.00007779352,0.000008269506],"category_scores_gemma":[0.000003931579,0.00007936803,0.000026864229,0.00015853191,0.000057015233,0.0000029775697,0.00002237921,0.000067155124,7.6374357e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013720404,0.000033996275,0.009217481,0.0000516801,0.000046779078,0.000001032904,0.00058253424,0.00009257113,0.9894339,0.00009582825,0.000041894444,0.00038862188],"study_design_scores_gemma":[0.0005379347,0.0000699941,0.005425997,0.000054186126,0.0000115138655,0.000005290673,0.0004368685,0.000020918733,0.992533,0.000052387742,0.00074146944,0.00011038226],"about_ca_topic_score_codex":0.000016361919,"about_ca_topic_score_gemma":0.00003682709,"teacher_disagreement_score":0.0045519755,"about_ca_system_score_codex":0.000009096614,"about_ca_system_score_gemma":0.000055244836,"threshold_uncertainty_score":0.32365343},"labels":[],"label_agreement":null},{"id":"W4410080838","doi":"10.1093/g3journal/jkaf097","title":"Mutant alleles of the <i>Caenorhabditis elegans rde-1</i> gene identified through chemical mutagenesis of an snRNA misprocessing reporter","year":2025,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Centers for Disease Control and Prevention; National Institutes of Health; University of Minnesota","keywords":"Biology; Mutant; Mutagenesis; Genetics; Allele; Gene; Mutation; Molecular biology","score_opus":0.006724694451250879,"score_gpt":0.28389713738927524,"score_spread":0.27717244293802434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410080838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8316621,0.15544894,0.011386518,0.000059454116,0.0005139658,0.000308819,0.00007146071,0.0000173295,0.00053140015],"genre_scores_gemma":[0.97896147,0.011830468,0.00799658,0.00015550652,0.0002382981,0.000032049793,0.000091302376,0.000057943125,0.0006363613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977305,0.00006570203,0.000838583,0.00062638865,0.0003115842,0.0004272716],"domain_scores_gemma":[0.99804646,0.000018964365,0.00032138612,0.0012575346,0.00027090008,0.000084776875],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020039128,0.0003456861,0.00041603288,0.000073493895,0.000110544366,0.000032773696,0.0007223787,0.00027392642,0.00002594529],"category_scores_gemma":[0.000017902685,0.0003073508,0.00028014288,0.00036093986,0.00025611633,0.000007730142,0.0003677419,0.00009751532,9.2048754e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003681744,0.00009909287,0.0021213903,0.00015644325,0.00020073325,0.000004903255,0.00025360487,0.0022148148,0.8994682,0.000022376456,0.00012992627,0.09529169],"study_design_scores_gemma":[0.00043875247,0.00009260861,0.0016268039,0.00003941093,0.00017030604,0.000049557344,0.00028528634,0.00020613782,0.9731026,0.00014729648,0.023541752,0.0002994405],"about_ca_topic_score_codex":0.000035957793,"about_ca_topic_score_gemma":0.00004946535,"teacher_disagreement_score":0.14729938,"about_ca_system_score_codex":0.000021364714,"about_ca_system_score_gemma":0.00023315637,"threshold_uncertainty_score":0.99993783},"labels":[],"label_agreement":null},{"id":"W4410166878","doi":"10.1007/s10460-025-10734-z","title":"Constructing counter imaginaries: a comparative analysis of social movement organizations’ framing of agricultural gene editing in the United States and European Union","year":2025,"lang":"en","type":"article","venue":"Agriculture and Human Values","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Framing (construction); European union; Social movement; Agriculture; Environmental sociology; Sociology; Political science; Political economy; Social science; Economics; Politics; International trade; Law; Geography","score_opus":0.005150220988886585,"score_gpt":0.2708344307711887,"score_spread":0.2656842097823021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410166878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980565,0.00034217382,0.00092440564,0.00009563527,0.000013216951,0.00006915546,0.000018743203,0.0000029458956,0.00047726143],"genre_scores_gemma":[0.9992021,0.000044779557,0.00012334614,0.000050121576,0.000042405205,0.0000016089525,0.00049919204,0.0000016832012,0.000034806864],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99952847,0.000082698374,0.00016097467,0.00010920935,0.000052479518,0.00006618338],"domain_scores_gemma":[0.99972963,0.000016608827,0.00006769417,0.000044696182,0.0001331728,0.000008217636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014718945,0.000076469034,0.00013356966,0.000068085756,0.00010215017,0.000023393395,0.00005376902,0.000027009066,0.0000014760967],"category_scores_gemma":[0.000010991911,0.00004684479,0.00002353768,0.00039922755,0.000088062676,0.0000036727884,0.00004774722,0.000046423625,1.7126414e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000049783403,0.00006091211,0.09552227,0.00009066451,0.0008003589,7.991263e-7,0.025783375,0.002308498,0.8702255,0.004057754,0.0009542185,0.00019069541],"study_design_scores_gemma":[0.0003056234,0.00005619687,0.82178396,0.000035068944,0.00034952475,0.0000015910628,0.06435783,0.00014108188,0.11247486,0.0000577566,0.0003275762,0.000108948225],"about_ca_topic_score_codex":0.00010837427,"about_ca_topic_score_gemma":0.00019116586,"teacher_disagreement_score":0.75775063,"about_ca_system_score_codex":0.00000446518,"about_ca_system_score_gemma":0.0000034297675,"threshold_uncertainty_score":0.1910275},"labels":[],"label_agreement":null},{"id":"W4410202499","doi":"10.7202/1117873ar","title":"Human Genome Editing and Sickle Cell Disease in Canada: Urgent and Unresolved Ethical Considerations","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"NOSM University; Lakehead University","funders":"Social Sciences and Humanities Research Council of Canada","keywords":"Disease; Genome; MEDLINE; Human genome; Medicine; Biology; Political science; Genetics; Gene; Law","score_opus":0.015250605933463016,"score_gpt":0.2917916374935215,"score_spread":0.2765410315600585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410202499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98555684,0.0065580797,0.0004888394,0.0069063953,0.00019804602,0.000063317486,0.000032313037,7.7153703e-7,0.00019538942],"genre_scores_gemma":[0.9983324,0.0001069995,0.00019840105,0.0012235645,0.00008759589,8.310424e-7,0.000005619493,0.000005313493,0.00003930604],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99946713,0.00003281553,0.00019616372,0.000097681856,0.000055526765,0.00015064931],"domain_scores_gemma":[0.9993251,0.000026906562,0.000038994935,0.00007503179,0.0000774277,0.0004565661],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021686827,0.000069928086,0.00009513148,0.00008411108,0.00010104429,0.00002678965,0.000044798417,0.00010971478,0.000009715086],"category_scores_gemma":[0.00026312968,0.00007499203,0.000018700137,0.000043210835,0.00011252982,0.0000016737011,0.000017990813,0.00035874904,4.414571e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007031188,0.000050706727,0.38638118,0.00090721616,0.0003117425,0.0017956141,0.0024781402,0.019018576,0.5484665,0.01958536,0.019385045,0.0015495613],"study_design_scores_gemma":[0.004404972,0.00046758616,0.800875,0.00065526704,0.00031153858,0.00021357436,0.0053965705,0.0018369242,0.09089013,0.0060979296,0.08742746,0.0014230139],"about_ca_topic_score_codex":0.31867504,"about_ca_topic_score_gemma":0.9743291,"teacher_disagreement_score":0.6556541,"about_ca_system_score_codex":0.00006430524,"about_ca_system_score_gemma":0.004557133,"threshold_uncertainty_score":0.80841583},"labels":[],"label_agreement":null},{"id":"W4410212252","doi":"10.1186/s13059-025-03586-7","title":"Predicting adenine base editing efficiencies in different cellular contexts by deep learning","year":2025,"lang":"en","type":"article","venue":"Genome biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Functional Genomics Center Zurich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Staatssekretariat für Bildung, Forschung und Innovation; Université de Genève; National Institutes of Health; National Science Foundation","keywords":"Biology; Genome editing; Computational biology; Guide RNA; In vivo; Base (topology); RNA editing; CRISPR; Computer science; Genetics; Messenger RNA; Gene","score_opus":0.0035405308282623242,"score_gpt":0.25686770034147605,"score_spread":0.2533271695132137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410212252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95423543,0.009399654,0.03536955,0.00007325277,0.0003465516,0.00012907272,0.00001002353,0.00002449679,0.000411956],"genre_scores_gemma":[0.99876684,0.000102055594,0.00012367746,0.000106029256,0.00031324543,0.000024704072,0.00017412953,0.000013094891,0.00037622385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989063,0.00006997187,0.00024958994,0.00036781968,0.00004187799,0.0003644439],"domain_scores_gemma":[0.99966913,0.000033713713,0.000048459107,0.00016738725,0.00003342595,0.000047897985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017265444,0.00016970531,0.00019355601,0.000088529545,0.00007775504,0.000012215866,0.00016466809,0.00017222766,0.000019827425],"category_scores_gemma":[0.00021892741,0.00015820096,0.00005667323,0.00010719576,0.000062245716,0.0000013871324,0.0001609161,0.00017122334,0.0000031389902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014235719,0.000024200686,0.06391327,0.000020374528,0.000020766434,0.0000018444496,0.00007770298,0.0014894714,0.9323579,0.000020584037,0.00005420521,0.0020054213],"study_design_scores_gemma":[0.001550568,0.0005090235,0.037356198,0.00004717735,0.000029989558,0.000006818769,0.0007510622,0.005271993,0.9104308,0.000046224948,0.043527663,0.000472474],"about_ca_topic_score_codex":0.000021022217,"about_ca_topic_score_gemma":0.000034574612,"teacher_disagreement_score":0.044531398,"about_ca_system_score_codex":0.000023244773,"about_ca_system_score_gemma":0.000016919681,"threshold_uncertainty_score":0.6451248},"labels":[],"label_agreement":null},{"id":"W4410221777","doi":"10.1016/j.jbc.2025.110222","title":"Phosphorylation of SNX17 impedes activation of Retriever-mediated sorting","year":2025,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Max-Planck-Gesellschaft; Deutsche Forschungsgemeinschaft","keywords":"Phosphorylation; Labrador Retriever; Cell biology; Chemistry; Sorting; Biochemistry; Biology; Computer science; Medicine; Pathology","score_opus":0.010028358648138867,"score_gpt":0.2886276122638028,"score_spread":0.2785992536156639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410221777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99183154,0.0007741092,0.0066289078,0.000041118423,0.000046390454,0.00003045984,0.000004241464,0.0000023569992,0.00064088043],"genre_scores_gemma":[0.9989809,0.0002391688,0.0006040837,0.000016651395,0.00007710804,5.787365e-7,0.000020168414,0.0000032248188,0.000058128488],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928576,0.0000129655555,0.0004439134,0.00008954396,0.0000822522,0.000085571286],"domain_scores_gemma":[0.9992792,0.00004418386,0.00036040225,0.000096960466,0.00018950974,0.000029741492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021662776,0.000076643024,0.00018195792,0.000022583194,0.00001402496,0.0000029775524,0.00011620284,0.00018486366,0.000020670734],"category_scores_gemma":[0.00079979916,0.000060462917,0.00011022241,0.00011297851,0.000050337807,0.0000025228048,0.000041192903,0.000100370205,9.478027e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013858968,0.000036947607,0.009561869,0.00005950278,0.000047007547,4.4702526e-7,0.0000084214935,0.00022125144,0.9886195,0.000004909227,0.00012450932,0.0011770454],"study_design_scores_gemma":[0.00031390486,0.00012143961,0.010023654,0.00006118701,0.000012221902,0.000004494012,0.00008092088,0.000047977454,0.9886899,0.000065270324,0.0005253682,0.000053689077],"about_ca_topic_score_codex":0.0000013815459,"about_ca_topic_score_gemma":8.507717e-8,"teacher_disagreement_score":0.007149352,"about_ca_system_score_codex":0.000011112483,"about_ca_system_score_gemma":0.000054754648,"threshold_uncertainty_score":0.24656062},"labels":[],"label_agreement":null},{"id":"W4410222487","doi":"10.1002/9781394280049.ch1","title":"Mitigating Heat Stress Response in CRISPR/Cas‐Mediated Edited Crops by Altering the Expression Pattern of Noncoding DNA","year":2025,"lang":"en","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"CRISPR; Heat stress; Biology; Expression (computer science); Computational biology; DNA; Genetics; Computer science; Gene; Programming language","score_opus":0.004442672250198799,"score_gpt":0.27934524695950536,"score_spread":0.27490257470930657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410222487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7249111,0.021667156,0.15793326,0.00089004845,0.0031760014,0.0025046282,0.0021091255,0.00030990018,0.08649876],"genre_scores_gemma":[0.94852424,0.0006412874,0.0005053447,0.00019169283,0.00044899347,0.000053332824,0.0004950061,0.00025602189,0.04888406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987419,0.000117951255,0.00033226897,0.00038452251,0.00015047131,0.00027285216],"domain_scores_gemma":[0.99929845,0.0000819311,0.00008856303,0.0004496264,0.00003102851,0.000050371484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022269001,0.00027420148,0.00026974166,0.00013781717,0.000031972777,0.000019497887,0.0002848913,0.00033924024,0.00015862989],"category_scores_gemma":[0.00014600944,0.00021684483,0.0000841167,0.00012427411,0.000048466805,0.000001435387,0.00022474189,0.0001899893,0.0000020899781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006634564,0.000023457074,0.0006043996,0.00014729229,0.000032171127,0.0000036856295,0.000077773126,0.00018889546,0.9322743,2.3946862e-7,0.066108406,0.00047305546],"study_design_scores_gemma":[0.00050145685,0.00007342601,0.0005095038,0.0009843181,0.000014810994,0.0000018088334,0.00026487294,0.00040506717,0.9580496,5.442487e-7,0.038920794,0.0002737855],"about_ca_topic_score_codex":0.00061283674,"about_ca_topic_score_gemma":0.0002626908,"teacher_disagreement_score":0.22361314,"about_ca_system_score_codex":0.000016422424,"about_ca_system_score_gemma":0.00005022346,"threshold_uncertainty_score":0.88426757},"labels":[],"label_agreement":null},{"id":"W4410340818","doi":"10.1038/s42003-025-08187-5","title":"Comparative analysis of multiple DNA double-strand break repair pathways in CRISPR-mediated endogenous tagging","year":2025,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; Institute of Genetics; Japan Science and Technology Agency; Princess Takamatsu Cancer Research Fund; Senri Life Science Foundation; Ministry of Education, Culture, Sports, Science and Technology; Astellas Pharma; Inamori Foundation; University of Tokyo; Japan Society for the Promotion of Science London; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Kato Memorial Bioscience Foundation; Uehara Memorial Foundation; Sumitomo Foundation; Kanae Foundation for the Promotion of Medical Science; Naito Foundation","keywords":"CRISPR; Amplicon; Computational biology; Biology; DNA repair; Homology directed repair; Genome editing; Cas9; DNA; Genetics; Homologous recombination; Gene; Nucleotide excision repair; Polymerase chain reaction","score_opus":0.04573109575936216,"score_gpt":0.3633269513669531,"score_spread":0.3175958556075909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410340818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9748087,0.00835824,0.008767176,0.00020419205,0.000075608885,0.00033598757,0.0001591968,0.000042383304,0.0072485176],"genre_scores_gemma":[0.99614775,0.0008701581,0.0017285652,0.00007117104,0.00000787196,0.000055648285,0.0010863496,0.0000049791374,0.000027516608],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909043,0.00012176925,0.00035546385,0.00022801664,0.000028687833,0.00017561675],"domain_scores_gemma":[0.99850273,0.00015303299,0.00007550918,0.0011468971,0.000091111724,0.00003072507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019336016,0.00011941335,0.0003264057,0.0003148073,0.00007056476,0.000004574865,0.0004725243,0.00014385828,0.0000073526694],"category_scores_gemma":[0.000072850286,0.00012326639,0.00014445708,0.0006811657,0.00017842941,0.0000019867055,0.0002697718,0.00011482231,0.0000015428102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078135934,0.00016990512,0.05909324,0.000016204503,0.0007738022,4.6492988e-7,0.00042478874,0.0024680248,0.9354248,0.001110417,0.000104611936,0.0003355953],"study_design_scores_gemma":[0.004657118,0.00031734523,0.10476638,0.00006623485,0.00085830933,0.000007369468,0.0017815751,0.05139756,0.7725272,0.00016991334,0.06278545,0.0006655156],"about_ca_topic_score_codex":0.00022504028,"about_ca_topic_score_gemma":0.0025494392,"teacher_disagreement_score":0.16289757,"about_ca_system_score_codex":0.000017173663,"about_ca_system_score_gemma":0.000061348546,"threshold_uncertainty_score":0.50266576},"labels":[],"label_agreement":null},{"id":"W4410396192","doi":"10.1056/nejmoa2504747","title":"Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease","year":2025,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; NIH Office of the Director; National Cancer Institute; National Institutes of Health; Children's Hospital of Philadelphia","keywords":"Genome editing; In vivo; Gene; Rare disease; Disease; Medicine; Genetics; Biology; Computational biology; Bioinformatics; Pathology; CRISPR","score_opus":0.005243302509100938,"score_gpt":0.267842131142233,"score_spread":0.26259882863313205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410396192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9684057,0.010324862,0.017936964,0.0020105676,0.00070620753,0.00011054871,0.0000045956735,0.000003364673,0.000497157],"genre_scores_gemma":[0.9944055,0.00073036057,0.0012880564,0.00042576878,0.002762483,0.000002316166,0.0000048834677,0.000011303518,0.00036931445],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99912673,0.000032660777,0.00036944868,0.00014607195,0.00015431813,0.00017075233],"domain_scores_gemma":[0.9994345,0.00002190841,0.00006772384,0.0001604275,0.000073168296,0.00024231608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015368486,0.00012042535,0.00020270843,0.00017986645,0.000021773869,0.0000072824623,0.00011492828,0.00004283036,0.000046414625],"category_scores_gemma":[0.00019219462,0.00009423471,0.000048246377,0.00015775868,0.000020637677,0.000002197329,0.00003774488,0.00010328621,7.930565e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000740304,0.000056635457,0.013260903,0.000052002502,0.00003911482,0.000290436,0.00056103396,0.007807361,0.6826545,0.000015916581,0.044138882,0.2503829],"study_design_scores_gemma":[0.035879515,0.0021969932,0.042050775,0.0010751864,0.00013606311,0.00032152233,0.0005600387,0.00016292674,0.24314411,0.00029417858,0.673776,0.00040273112],"about_ca_topic_score_codex":0.000013523891,"about_ca_topic_score_gemma":0.00002339401,"teacher_disagreement_score":0.62963706,"about_ca_system_score_codex":0.00001948681,"about_ca_system_score_gemma":0.00007493196,"threshold_uncertainty_score":0.384278},"labels":[],"label_agreement":null},{"id":"W4410398599","doi":"10.1101/2025.05.10.652755","title":"Orthogonal resistance mechanisms of classical- and induced-proximity inhibitors","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Harvard University; National Science Foundation","keywords":"Resistance (ecology); Computer science; Biology; Ecology","score_opus":0.008565311814640283,"score_gpt":0.24244469479771105,"score_spread":0.23387938298307076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410398599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9718498,0.002395223,0.023986712,0.0001347345,0.0007993476,0.00044334334,0.00027752452,0.000063901934,0.000049442413],"genre_scores_gemma":[0.9902751,0.00030169715,0.008973279,0.00007194371,0.00023605673,0.00006453038,9.332742e-7,0.0000451678,0.0000312893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981697,0.00006047731,0.00042785297,0.0008048699,0.0002180527,0.0003190073],"domain_scores_gemma":[0.9985116,0.000018953566,0.00020660643,0.0008552143,0.00025162546,0.00015597614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031134597,0.00039049084,0.0004105168,0.00012767132,0.00006639394,0.000040145842,0.00030451524,0.0006486761,0.000003983909],"category_scores_gemma":[0.000165037,0.0004382172,0.00013155758,0.00018299186,0.00009200776,0.000004823499,0.0006833532,0.00040364405,0.0000010948684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035688194,0.00004897887,0.00072180596,0.00050160004,0.0001059861,0.000004489561,0.0000026004632,0.000040095387,0.9962554,0.0020553702,0.00022405271,0.0000039452348],"study_design_scores_gemma":[0.00030258976,0.000055497683,0.012834914,0.00029476912,0.00006854003,9.715785e-9,0.0000020023297,0.000054247368,0.9825571,0.000020122707,0.0033763251,0.00043387414],"about_ca_topic_score_codex":0.00000705906,"about_ca_topic_score_gemma":0.000009747911,"teacher_disagreement_score":0.018425332,"about_ca_system_score_codex":0.000033551227,"about_ca_system_score_gemma":0.00036790382,"threshold_uncertainty_score":0.99980694},"labels":[],"label_agreement":null},{"id":"W4410419059","doi":"10.1093/nar/gkaf382","title":"CRISPR-BEasy: a free web-based service for designing sgRNA tiling libraries for CRISPR-dependent base editing screens","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"CRISPR; Genome editing; Ensembl; Guide RNA; Biology; Computational biology; Subgenomic mRNA; Computer science; Cas9; Web application; World Wide Web; Genetics; Gene; Genomics; Genome","score_opus":0.039347491876035534,"score_gpt":0.3724884196380504,"score_spread":0.33314092776201487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410419059","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.117040716,0.002065805,0.8729804,0.0032272579,0.00044610768,0.0018100073,0.00027311608,0.000120834404,0.0020357354],"genre_scores_gemma":[0.9274807,0.000043766217,0.06878025,0.0007647225,0.0009356388,0.0005727013,0.00019218268,0.00010354839,0.0011265129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99756026,0.00010746021,0.00035436367,0.00069029065,0.00038714477,0.0009004568],"domain_scores_gemma":[0.99794924,0.00037593232,0.00004974028,0.0007749176,0.000675414,0.00017474782],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014461045,0.00025665952,0.00025566574,0.0002689163,0.0005484033,0.00020775704,0.00075191,0.00028242005,0.000030085044],"category_scores_gemma":[0.0016530092,0.00027318153,0.00017360278,0.00038702146,0.00009769393,0.00001516701,0.00043999852,0.00031701918,0.0000059961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056226144,0.000089831905,0.0010412982,0.00079973787,0.00011945217,0.000004865626,0.00010960655,0.0025410645,0.9535089,0.0005396033,0.035107266,0.0055760955],"study_design_scores_gemma":[0.0027767504,0.000377467,0.0002483104,0.00018305036,0.000041729603,0.0000024705323,0.0009741893,0.047056183,0.89301103,0.0007097625,0.054301605,0.0003174411],"about_ca_topic_score_codex":0.000047617545,"about_ca_topic_score_gemma":0.00010830749,"teacher_disagreement_score":0.81043994,"about_ca_system_score_codex":0.00004866756,"about_ca_system_score_gemma":0.00048516627,"threshold_uncertainty_score":0.99997205},"labels":[],"label_agreement":null},{"id":"W4410430731","doi":"10.1038/s41587-025-02676-y","title":"Author Correction: Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A","year":2025,"lang":"en","type":"erratum","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"","keywords":"Fusion; Base (topology); Computer science; Computational biology; Biology; Linguistics; Philosophy; Mathematics","score_opus":0.005774211474567483,"score_gpt":0.3029117542339779,"score_spread":0.29713754275941046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410430731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9027336,0.02666032,0.008946717,0.0013899194,0.056142315,0.0012183214,0.0002592551,0.00015004183,0.0024994942],"genre_scores_gemma":[0.9786187,0.00035781055,0.0025042181,0.00017943997,0.0015714528,0.000024221566,0.00050312077,0.00006874265,0.016172305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986029,0.000028568329,0.00034342697,0.00060287234,0.00012663669,0.00029558464],"domain_scores_gemma":[0.99932855,0.000012358703,0.00013114029,0.0004209478,0.000057234793,0.000049761155],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00019601047,0.0002753579,0.00037262464,0.00059709774,0.00006681949,0.000008968884,0.00022614643,0.0037993488,0.0000054986363],"category_scores_gemma":[0.00027564986,0.00029189567,0.00006644104,0.00030596918,0.00007508811,7.840297e-7,0.0004051835,0.0014161431,4.561881e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004818773,0.00006998663,0.00015893727,0.0003014333,0.000048495614,0.000025098343,0.000038513288,0.0011931849,0.834916,0.0000841779,0.15798567,0.0051302984],"study_design_scores_gemma":[0.0006169409,0.0003984978,0.000535537,0.0011341231,0.00005824301,0.00013592605,0.00018247975,0.004259252,0.6166347,0.000018962663,0.3754638,0.00056152197],"about_ca_topic_score_codex":0.00006259763,"about_ca_topic_score_gemma":0.00021654183,"teacher_disagreement_score":0.21828131,"about_ca_system_score_codex":0.00003949994,"about_ca_system_score_gemma":0.000095236035,"threshold_uncertainty_score":0.9999533},"labels":[],"label_agreement":null},{"id":"W4410440523","doi":"10.3390/ijms26104779","title":"Advances in Genome Editing Through Haploid Induction Systems","year":2025,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Global Institute for Water Security; National Research Council Canada; Agriculture and Agri-Food Canada; University of Saskatchewan","funders":"National Research Council Canada","keywords":"Genome editing; CRISPR; Biology; Timeline; Transformative learning; Genome; Ploidy; Computational biology; Emerging technologies; Computer science; Gene; Genetics; Geography","score_opus":0.017934176203380076,"score_gpt":0.3810353939751544,"score_spread":0.36310121777177434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410440523","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001513296,0.9816253,0.013331973,0.00003416242,0.0032926472,0.00010693154,0.00000957931,0.0000024320777,0.0014456265],"genre_scores_gemma":[0.002686928,0.99552685,0.0007357432,0.0000225843,0.0009498542,0.000008096613,0.000015459726,0.000009586007,0.000044899887],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985477,0.000071008435,0.0005855241,0.0002283764,0.00042079316,0.00014663003],"domain_scores_gemma":[0.9992172,0.000023258724,0.0004317954,0.000096384516,0.00020115823,0.000030201512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044789532,0.00017008223,0.00038516207,0.0003151969,0.000032743596,0.00010468871,0.0007689344,0.000117665884,0.0000030576928],"category_scores_gemma":[0.00016429441,0.00014218764,0.00022756177,0.00018347501,0.00009390084,0.00002386426,0.00010892614,0.00018621483,0.0000011532054],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012506882,0.00008366874,0.000015061112,0.00240773,0.00028454157,0.00017696216,0.00013055257,0.0213776,0.003033357,0.0014608019,0.00010555545,0.9709117],"study_design_scores_gemma":[0.0001129115,0.000091506845,0.0000012986027,0.004033819,0.000046291025,0.0002618877,0.0001174049,0.000013402112,0.00034744534,0.000059476046,0.99476606,0.00014851478],"about_ca_topic_score_codex":0.0000067916258,"about_ca_topic_score_gemma":0.0000039928905,"teacher_disagreement_score":0.9946605,"about_ca_system_score_codex":0.00004936851,"about_ca_system_score_gemma":0.0003117692,"threshold_uncertainty_score":0.5798244},"labels":[],"label_agreement":null},{"id":"W4410452916","doi":"10.5376/tgmb.2024.14.0026","title":"CRISPR/Cas9-Mediated Trait Improvement in Kiwifruit: Current Progress and Future Directions","year":2024,"lang":"en","type":"article","venue":"Tree Genetics and Molecular Breeding","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Trait; Genome editing; Biology; Cas9; Current (fluid); Computational biology; Biotechnology; Genetics; Computer science; Engineering; Gene; Programming language","score_opus":0.00754966324367078,"score_gpt":0.2897549199508866,"score_spread":0.2822052567072158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410452916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8419018,0.15342487,0.003010176,0.0005220502,0.000578522,0.00029578333,0.000029848019,0.000037755304,0.00019919238],"genre_scores_gemma":[0.9850501,0.013462295,0.0007960348,0.00005491803,0.0004459577,0.000057620946,0.000055348617,0.00004513197,0.000032593452],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988187,0.000016095044,0.00022320224,0.00049275113,0.00013213778,0.00031710876],"domain_scores_gemma":[0.99962854,0.000007731824,0.00002292731,0.00016977216,0.00003220119,0.00013882334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013099091,0.00022921659,0.00015299219,0.00013948823,0.0000580186,0.00010624333,0.00008553098,0.00012634372,0.000004683895],"category_scores_gemma":[0.000010223745,0.00022893256,0.00006006335,0.00017938224,0.000065277374,0.0000041306403,0.00013023282,0.00016250154,9.440048e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011489301,0.00003596344,0.0010446077,0.00015967459,0.00005456604,0.000024597788,0.00023923976,0.000027964548,0.5425375,0.00016530095,0.00017621045,0.4555229],"study_design_scores_gemma":[0.0018409208,0.0011776303,0.027864946,0.0003018794,0.00019341569,0.00016027429,0.000561741,0.010674863,0.2636982,0.00026388824,0.69200927,0.001252953],"about_ca_topic_score_codex":0.000008015427,"about_ca_topic_score_gemma":0.000057073205,"teacher_disagreement_score":0.6918331,"about_ca_system_score_codex":0.0000143642355,"about_ca_system_score_gemma":0.00003465131,"threshold_uncertainty_score":0.93355995},"labels":[],"label_agreement":null},{"id":"W4410461307","doi":"10.1016/j.celrep.2025.115726","title":"Machine-guided cell-fate engineering","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Army Research Office; Intelligence Advanced Research Projects Activity; Office of the Director of National Intelligence","keywords":"Cell fate determination; Computer science; Computational biology; Cell biology; Biology; Transcription factor; Genetics; Gene","score_opus":0.0041956543395438575,"score_gpt":0.2550729750604013,"score_spread":0.25087732072085744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410461307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8206783,0.009179622,0.082663424,0.00008868661,0.0016240408,0.00028915075,0.0000039585993,0.000097694385,0.08537515],"genre_scores_gemma":[0.98747283,0.00013581345,0.0012120964,0.000101962505,0.00008861949,0.000013051487,0.00004175528,0.000020100166,0.010913762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919903,0.000005986278,0.00023188902,0.0002905237,0.00006879388,0.00020376017],"domain_scores_gemma":[0.9994471,0.000004894578,0.000043324268,0.0004132467,0.00003252858,0.00005889316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010777569,0.00013723946,0.00010776022,0.000050836446,0.000033140146,0.000017823959,0.000078025856,0.000095711905,0.000018173148],"category_scores_gemma":[0.000035026067,0.00014372346,0.00007983723,0.00008542756,0.000009843148,0.0000012104542,0.000089020694,0.000073377356,0.0000045541483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000030257431,0.000023877954,0.0016544687,0.00007866647,0.000014762285,0.0000760185,0.0000107224205,0.009523557,0.9806196,0.00001118469,0.0075449906,0.00043913224],"study_design_scores_gemma":[0.00012596142,0.0000167602,0.0006533712,0.000009890822,0.000014219336,0.00003843719,0.0000054618918,0.00067690987,0.80943465,0.000015191623,0.18887529,0.00013387117],"about_ca_topic_score_codex":0.000009652014,"about_ca_topic_score_gemma":0.0000015515304,"teacher_disagreement_score":0.18133031,"about_ca_system_score_codex":0.000009719382,"about_ca_system_score_gemma":0.000042192725,"threshold_uncertainty_score":0.5860873},"labels":[],"label_agreement":null},{"id":"W4410467963","doi":"10.1101/2025.05.16.654562","title":"Heterobifunctional Protein Binders Enable Cell Type-Specific Killing Through In-cell Enrichment","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Helmholtz-Zentrum Berlin für Materialien und Energie; Bundesministerium für Bildung und Forschung; European Synchrotron Radiation Facility","keywords":"Cell; Cell biology; Chemistry; Computational biology; Biology; Biochemistry","score_opus":0.010344416883162424,"score_gpt":0.23239276190106553,"score_spread":0.2220483450179031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410467963","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95150983,0.010168248,0.03444941,0.00008149611,0.0020997678,0.0011798313,0.00010421894,0.00011028207,0.00029694027],"genre_scores_gemma":[0.9890393,0.0011332706,0.008760331,0.000117949516,0.00045348232,0.00021179658,0.0000042022193,0.000078286896,0.00020140232],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975559,0.00006699763,0.00047210325,0.0010913544,0.00024993694,0.0005636741],"domain_scores_gemma":[0.9985113,0.000013019216,0.00016117378,0.0009783938,0.0002170058,0.000119121],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002662272,0.0005247607,0.00037075355,0.00017790416,0.00009142422,0.00009245058,0.00042257438,0.0006174021,0.0000372108],"category_scores_gemma":[0.000024425088,0.00061008777,0.00015784655,0.00033902805,0.00005182197,0.00000802909,0.00049764774,0.0005652499,0.000028327153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004863166,0.00016658695,0.00077890354,0.0004568432,0.00004866447,0.000011869423,0.00000820182,0.008107271,0.9895403,0.00004688122,0.0007845724,0.000001303712],"study_design_scores_gemma":[0.0005282519,0.00008075733,0.0008278457,0.00021195567,0.000026207616,1.0755133e-8,0.000006750178,0.00018812965,0.94630486,0.000003245126,0.051201608,0.00062040583],"about_ca_topic_score_codex":0.000031483178,"about_ca_topic_score_gemma":0.0000027422404,"teacher_disagreement_score":0.050417036,"about_ca_system_score_codex":0.00015841587,"about_ca_system_score_gemma":0.00043057,"threshold_uncertainty_score":0.99963504},"labels":[],"label_agreement":null},{"id":"W4410487421","doi":"10.1016/j.ibmb.2025.104329","title":"Silkworm mutagenesis using a ribonucleoprotein-based CRISPR/Cas12a system","year":2025,"lang":"en","type":"article","venue":"Insect Biochemistry and Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Agriculture Research System of China; Natural Science Foundation of Chongqing; Ministry of Agriculture and Rural Affairs of the People's Republic of China; National Natural Science Foundation of China","keywords":"CRISPR; Genome editing; Trans-activating crRNA; Cas9; Biology; Ribonucleoprotein; Computational biology; Genetics; Gene; Mutagenesis; Genome; Genome engineering; Mutant; RNA","score_opus":0.006675855022093764,"score_gpt":0.30596345159722793,"score_spread":0.29928759657513415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410487421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84811544,0.0047694407,0.14567053,0.00009765444,0.00017800218,0.00021203006,0.000033422333,0.000051974876,0.0008715255],"genre_scores_gemma":[0.99584395,0.000037480826,0.0032874753,0.00042475353,0.00010907987,0.000040919367,0.000110447814,0.000029659277,0.0001162659],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998509,0.00006214496,0.00029308954,0.00066380866,0.00007128455,0.0004006847],"domain_scores_gemma":[0.99917257,0.00001606025,0.000072505376,0.00053516653,0.00008616751,0.00011754775],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016291023,0.00032286753,0.00027390043,0.00009458462,0.00013692338,0.000032479085,0.00022136171,0.00045755238,0.000006893828],"category_scores_gemma":[0.00008964065,0.00033579228,0.0001459538,0.0001926228,0.00016758704,0.0000018171484,0.0001672531,0.00013305116,0.0000016509308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007753253,0.000032225576,0.0008662588,0.00026833478,0.00010312972,0.000020788966,0.0000069640387,0.00026133156,0.9967643,0.00021067553,0.00006882437,0.0013196366],"study_design_scores_gemma":[0.0006862037,0.00010865405,0.0001479425,0.0000820984,0.00006965665,0.000056708028,0.00005392303,0.0015185985,0.9936409,0.000050597613,0.00324399,0.00034071298],"about_ca_topic_score_codex":0.00006958003,"about_ca_topic_score_gemma":0.000005544382,"teacher_disagreement_score":0.1477285,"about_ca_system_score_codex":0.000038670543,"about_ca_system_score_gemma":0.00016172121,"threshold_uncertainty_score":0.9999094},"labels":[],"label_agreement":null},{"id":"W4410510202","doi":"10.1016/j.talanta.2025.128367","title":"Dual nuclease-amplified sensitive biosensor for enrofloxacin detection using a DNase I-assisted CRISPR/Cas12a (CRISPR-DNase I) system","year":2025,"lang":"en","type":"article","venue":"Talanta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Natural Science Foundation of Zhejiang Province; Taishan Scholar Foundation of Shandong Province","keywords":"CRISPR; Chemistry; Nuclease; Biosensor; Deoxyribonuclease I; DNA; Aptamer; Nucleic acid; Detection limit; Rolling circle replication; Molecular biology; Biochemistry; Polymerase; Chromatography; Gene; Biology","score_opus":0.014020154617169475,"score_gpt":0.3073558709916091,"score_spread":0.2933357163744396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410510202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90691435,0.00025057344,0.091019966,0.000042399715,0.0005483457,0.0005221411,0.00018934695,0.00008062675,0.00043224555],"genre_scores_gemma":[0.99804795,0.000017430684,0.00080257776,0.00011937978,0.00030750845,0.00003576024,0.00014576109,0.000044029275,0.00047959373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864674,0.000057366837,0.0003070418,0.00050609524,0.00010600694,0.000376724],"domain_scores_gemma":[0.9992396,0.000036757814,0.000079646954,0.00039937056,0.00013666127,0.00010791673],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015496052,0.00026706856,0.00025885087,0.00013369661,0.00019051365,0.000049088372,0.00009289373,0.00022252851,0.0000030365454],"category_scores_gemma":[0.00009604787,0.00028059015,0.00017515756,0.00017819287,0.00004580998,0.0000048677484,0.0000910248,0.000101338606,0.000007769019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003063819,0.00004464187,0.000060227318,0.00021536135,0.00012648507,0.00002874584,0.000046401372,0.00027645665,0.996506,0.000070239,0.0005656941,0.0017533748],"study_design_scores_gemma":[0.0012133997,0.00013815211,0.0009363528,0.00010184027,0.00014944114,0.00016487419,0.0008495278,0.007064493,0.98386717,0.0000039071456,0.005192713,0.00031813528],"about_ca_topic_score_codex":0.00009650727,"about_ca_topic_score_gemma":0.000101200945,"teacher_disagreement_score":0.0911336,"about_ca_system_score_codex":0.00007255743,"about_ca_system_score_gemma":0.00006676843,"threshold_uncertainty_score":0.99996465},"labels":[],"label_agreement":null},{"id":"W4410521520","doi":"10.1038/s41551-025-01399-4","title":"Treatment of a metabolic liver disease in mice with a transient prime editing approach","year":2025,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Universität Zürich; Novartis Stiftung für Medizinisch-Biologische Forschung; Eidgenössische Technische Hochschule Zürich; Staatssekretariat für Bildung, Forschung und Innovation; Novartis Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institutes of Health; National Science Foundation","keywords":"Genome editing; RNA editing; RNA; Messenger RNA; Locus (genetics); In vivo; Molecular biology; Computational biology; Chemistry; Biology; Gene; Genetics; Biochemistry; Genome","score_opus":0.002291410172772034,"score_gpt":0.23847322326632184,"score_spread":0.2361818130935498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410521520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73884314,0.043070167,0.21672921,0.0001783279,0.00034586867,0.00046545785,0.0000332085,0.000037682225,0.0002969361],"genre_scores_gemma":[0.99319047,0.00023408762,0.0062561207,0.000018577115,0.00012863406,0.00003766949,0.000060375416,0.0000131707775,0.000060880684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992594,0.000008132075,0.00015943295,0.00024387095,0.00012848304,0.00020065562],"domain_scores_gemma":[0.99969447,0.00001099259,0.000018160365,0.0001518171,0.000022720516,0.00010184542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050177267,0.0001512595,0.00018107209,0.00014046639,0.000010863435,0.000005008377,0.0000921973,0.0001801043,0.000002108144],"category_scores_gemma":[0.00004185528,0.00012084267,0.00006439268,0.00027657833,0.000032214826,0.0000019971533,0.000019980995,0.0001255354,2.0648596e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042824584,0.0012516206,0.0035480997,0.0008807142,0.0005103023,0.000088758105,0.0004958597,0.044154022,0.92576647,0.0011440181,0.0001482722,0.021583615],"study_design_scores_gemma":[0.007045858,0.00083280925,0.0960248,0.0005122127,0.0003628947,0.00003860946,0.00012977743,0.19165148,0.4774779,0.0000058022238,0.22496706,0.0009507911],"about_ca_topic_score_codex":0.000014393145,"about_ca_topic_score_gemma":0.0000035329351,"teacher_disagreement_score":0.44828856,"about_ca_system_score_codex":0.000016064954,"about_ca_system_score_gemma":0.000060625225,"threshold_uncertainty_score":0.49278212},"labels":[],"label_agreement":null},{"id":"W4410551268","doi":"10.1089/crispr.2025.0051","title":"Summitting CRISPR for Human Heritable Genome Editing","year":2025,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"CRISPR; Genome editing; Biology; Genome; Computational biology; Genetics; Human genome; Evolutionary biology; Gene","score_opus":0.00982039644892763,"score_gpt":0.3416341780640494,"score_spread":0.33181378161512176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410551268","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45101327,0.008185041,0.53208506,0.0020350155,0.0014566721,0.0003888181,0.000015939217,0.00003371896,0.0047864635],"genre_scores_gemma":[0.99286795,0.000118908916,0.0018543033,0.00043837816,0.002052794,0.000021094482,0.000015593587,0.000026680058,0.0026042892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902415,0.00003882737,0.00028486273,0.00018376023,0.00009573063,0.00037267775],"domain_scores_gemma":[0.99944055,0.00002852396,0.00008180421,0.00025651098,0.00012783671,0.00006475985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006929651,0.00014410655,0.00013787005,0.00005114292,0.00064605015,0.000113570735,0.0003376585,0.00008432927,0.00002525008],"category_scores_gemma":[0.00014890915,0.00011379247,0.00015232751,0.00008421806,0.000042434596,0.000004506952,0.00010798491,0.00022296725,0.0000026383605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028307493,0.00002616596,0.0006832024,0.000051525058,0.0001276928,0.000002790814,0.00013369063,0.0014349896,0.97782224,0.00048952125,0.016525099,0.0026747817],"study_design_scores_gemma":[0.0013405215,0.00024335059,0.0024597542,0.00008989289,0.0001352905,0.0001246233,0.0018349353,0.00047699822,0.56550336,0.0024185092,0.42500532,0.0003674453],"about_ca_topic_score_codex":0.0000072110997,"about_ca_topic_score_gemma":0.000013155893,"teacher_disagreement_score":0.5418547,"about_ca_system_score_codex":0.000020228797,"about_ca_system_score_gemma":0.00004974719,"threshold_uncertainty_score":0.4968961},"labels":[],"label_agreement":null},{"id":"W4410551380","doi":"10.1089/crispr.2025.0058","title":"A Reset for Bioethics: A Statement from the Global Observatory for Genome Editing","year":2025,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Society of Canada; Royal Ottawa Mental Health Centre; Dalhousie University","funders":"","keywords":"Statement (logic); Reset (finance); Bioethics; Observatory; Genome editing; Genome; Computer science; Computational biology; Biology; Epistemology; Philosophy; Astronomy; Genetics; Physics; Business","score_opus":0.03617393876455207,"score_gpt":0.394480909245157,"score_spread":0.35830697048060495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410551380","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14154348,0.010377492,0.8309329,0.014515882,0.0013035379,0.0006354962,0.00051501015,0.000011618562,0.00016458008],"genre_scores_gemma":[0.9811339,0.000764959,0.009335619,0.003978364,0.004070775,0.00015778115,0.000141264,0.000029689041,0.00038766928],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99916595,0.00005249307,0.00025543637,0.00015864968,0.00010187026,0.00026557155],"domain_scores_gemma":[0.99934655,0.00011145083,0.00008174359,0.00026665133,0.00014705402,0.000046552028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009245065,0.00011538751,0.000100811856,0.000010360392,0.00039660375,0.00008817959,0.0003997253,0.00007751723,0.0000072415855],"category_scores_gemma":[0.00027395514,0.00007050835,0.00014577716,0.000056682635,0.0000794798,0.0000027021347,0.00010433713,0.00015563644,8.811535e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015318805,0.0001768771,0.007624658,0.00024498778,0.0023042317,0.0000071052054,0.0017688005,0.00736962,0.47837558,0.009500544,0.47104785,0.020047871],"study_design_scores_gemma":[0.0016950009,0.0002619997,0.0042668255,0.00007166576,0.00018249718,0.00001806805,0.0023539031,0.0010006264,0.0515271,0.017597174,0.9208056,0.00021953783],"about_ca_topic_score_codex":0.000027220969,"about_ca_topic_score_gemma":0.000090099515,"teacher_disagreement_score":0.83959043,"about_ca_system_score_codex":0.000038805956,"about_ca_system_score_gemma":0.00013028985,"threshold_uncertainty_score":0.30503953},"labels":[],"label_agreement":null},{"id":"W4410606269","doi":"10.1016/j.jcyt.2025.05.007","title":"International Call for a 10-Year Moratorium on Heritable Human Genome Editing","year":2025,"lang":"en","type":"editorial","venue":"Cytotherapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Society for Cellular Therapy","funders":"","keywords":"Genome editing; Biology; Genome; Genetics; Gene","score_opus":0.006191552544957316,"score_gpt":0.31685718930271434,"score_spread":0.31066563675775705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410606269","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012263631,0.0014609313,0.014175664,0.00017651329,0.96822286,0.00073380093,0.0015886725,0.00007293357,0.012342274],"genre_scores_gemma":[0.001205836,0.0004126388,0.0010643005,0.0001173768,0.9557307,0.000185236,0.0038620597,0.00009709723,0.037324786],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99885213,0.0000137008365,0.00021507783,0.00045689425,0.00020705248,0.00025515724],"domain_scores_gemma":[0.9992982,0.00003560985,0.000077179735,0.00032924142,0.00020824956,0.000051524035],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014369667,0.00025195323,0.00021932127,0.00006983963,0.00008243701,0.000060968363,0.00035409143,0.0005437161,0.00009110218],"category_scores_gemma":[0.00012928808,0.00027273744,0.0001527035,0.000042516498,0.000022173252,0.0000016711468,0.00005234138,0.00018577567,0.000006745587],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000861172,0.000030491712,0.0000028783268,0.000052376487,0.00013574332,0.000001007799,0.000015046883,0.00015884453,0.14552605,0.000023206207,0.8537081,0.00026013408],"study_design_scores_gemma":[0.0008765815,0.00029686117,0.0000061546652,0.000043987224,0.000013544545,2.382359e-7,0.000010919803,0.000017384908,0.021977667,0.000020508684,0.97649467,0.00024148032],"about_ca_topic_score_codex":0.000008395984,"about_ca_topic_score_gemma":0.000009233468,"teacher_disagreement_score":0.12354839,"about_ca_system_score_codex":0.000051261282,"about_ca_system_score_gemma":0.00011609488,"threshold_uncertainty_score":0.99997246},"labels":[],"label_agreement":null},{"id":"W4410746274","doi":"10.1111/pbi.70146","title":"A highly efficient <scp>CRISPR</scp> ‐Cas9‐based gene‐editing system in oat ( <i>Avena sativa L.</i> )","year":2025,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Prairie Oat Growers Association; Agriculture Funding Consortium; McGill University","keywords":"Avena; Biology; CRISPR; Genome editing; Gene; Cas9; Genetics; Computational biology; Botany","score_opus":0.004644845137102465,"score_gpt":0.23620674617597165,"score_spread":0.23156190103886917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410746274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8891722,0.004471502,0.1038121,0.0006101609,0.0009056259,0.00020376679,0.000053492113,0.00009425586,0.0006769227],"genre_scores_gemma":[0.9968214,0.00023475624,0.0023797662,0.00016706386,0.00021452983,0.0000151934255,0.000043032825,0.000022722388,0.00010153921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983811,0.000062221145,0.00045758972,0.00039071622,0.00015231353,0.0005560822],"domain_scores_gemma":[0.9993256,0.000056259898,0.00014252284,0.0003345405,0.000054446922,0.000086668515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004043877,0.00025488622,0.0002883182,0.00044010975,0.00015675643,0.00004357395,0.00038450482,0.0005599647,0.0000017036797],"category_scores_gemma":[0.0002231516,0.00024192495,0.00011621434,0.00033951903,0.00008683152,0.0000026100042,0.00014163945,0.00060421845,0.000008212622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024309755,0.00007950128,0.0023105424,0.00009593807,0.000085717395,0.00023251864,0.00004635862,0.013911669,0.97834224,0.00045038213,0.0024402584,0.0019805653],"study_design_scores_gemma":[0.0011067142,0.00012756682,0.0006200328,0.00023816721,0.00003151693,0.0007873911,0.00060291635,0.008821139,0.9550653,0.000018010618,0.032464843,0.00011638239],"about_ca_topic_score_codex":0.000013138485,"about_ca_topic_score_gemma":0.000024893245,"teacher_disagreement_score":0.10764922,"about_ca_system_score_codex":0.00009102227,"about_ca_system_score_gemma":0.0001334103,"threshold_uncertainty_score":0.98654133},"labels":[],"label_agreement":null},{"id":"W4410823796","doi":"10.1128/mbio.00382-25","title":"CRISPR/dCas-mediated counter-silencing: reprogramming dCas proteins into antagonists of xenogeneic silencers","year":2025,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Jürgen Manchot Stiftung","keywords":"Biology; Gene silencing; Nucleoid; Genetics; RNA interference; CRISPR; CRISPR interference; Promoter; Computational biology; RNA; Gene; Cas9; Cell biology; Gene expression; Escherichia coli","score_opus":0.0049135115125682055,"score_gpt":0.3058854869972209,"score_spread":0.3009719754846527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410823796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97904015,0.0031063177,0.016201736,0.00013520553,0.0003014098,0.000357891,0.000015954713,0.000035265766,0.0008060577],"genre_scores_gemma":[0.9968051,0.00019676606,0.0022686608,0.00010569643,0.00008877717,0.00004728838,0.00007822841,0.000020199388,0.00038933463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988549,0.000026249936,0.00030610632,0.0004040662,0.00013071658,0.00027795846],"domain_scores_gemma":[0.9992607,0.000012639777,0.00007413757,0.0004804603,0.00010520867,0.00006683238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018928915,0.00018006934,0.00019437808,0.000082635444,0.00007265893,0.000023503655,0.00022804254,0.00016431665,0.000016787078],"category_scores_gemma":[0.00012974761,0.0001845392,0.00010449201,0.0002147478,0.00009284031,0.0000030615881,0.00013143336,0.00009669319,0.000006609541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041964697,0.000051521067,0.0028064905,0.00016143372,0.000069512644,0.0000053213143,0.00018130871,0.00014812841,0.9895309,0.000036396723,0.0007613453,0.006205652],"study_design_scores_gemma":[0.00037877267,0.00019158737,0.001532377,0.000079303274,0.000027437114,0.000005720153,0.0002809567,0.00021977742,0.9729018,0.000040481278,0.02415507,0.00018667043],"about_ca_topic_score_codex":0.0002130339,"about_ca_topic_score_gemma":0.000092275404,"teacher_disagreement_score":0.023393722,"about_ca_system_score_codex":0.00003179754,"about_ca_system_score_gemma":0.00011817458,"threshold_uncertainty_score":0.75252897},"labels":[],"label_agreement":null},{"id":"W4410849711","doi":"10.1016/j.jacl.2025.04.096","title":"Long-term monitoring of LPL gene replacement therapy: A lexicon of lessons for gene editing or oligonucleotide-based lipid lowering treatments","year":2025,"lang":"en","type":"article","venue":"Journal of clinical lipidology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Chicoutimi","funders":"","keywords":"Medicine; Lexicon; Oligonucleotide; Genetic enhancement; Term (time); Gene; Computational biology; Bioinformatics; Genetics; Natural language processing; Biology; Computer science","score_opus":0.07044214352769199,"score_gpt":0.4555174260628346,"score_spread":0.38507528253514256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410849711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94120073,0.0011771129,0.053413182,0.00031242953,0.0036414545,0.00020287366,0.000015413487,0.000004177089,0.000032627806],"genre_scores_gemma":[0.98390585,0.001279335,0.011359557,0.000078215475,0.003206246,0.000010986268,0.0000097795755,0.000022133197,0.00012790006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977995,0.00009279382,0.0014913804,0.0002464471,0.00012639895,0.00024346095],"domain_scores_gemma":[0.9981779,0.00035692568,0.0007952274,0.00030481996,0.00027540975,0.00008970411],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009896132,0.00017481926,0.0006821181,0.00011644382,0.00003761804,0.000007071213,0.00024896426,0.00023802088,0.000012615711],"category_scores_gemma":[0.0007995406,0.00014161893,0.00044566308,0.00008654498,0.00009217585,0.000004873188,0.00007164331,0.00015974106,2.0933881e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0048517687,0.0005654533,0.16267458,0.00017084938,0.0008978899,0.0000043581827,0.000029364193,0.0024152007,0.7978441,0.000012155132,0.00026645808,0.030267838],"study_design_scores_gemma":[0.0052845674,0.0034762663,0.06192976,0.00019747809,0.00013342945,0.000016892536,0.00002896513,0.000081953585,0.9273257,0.00001811802,0.0013916475,0.000115211435],"about_ca_topic_score_codex":0.0000026515154,"about_ca_topic_score_gemma":0.0000035876074,"teacher_disagreement_score":0.12948163,"about_ca_system_score_codex":0.000018363091,"about_ca_system_score_gemma":0.00027946575,"threshold_uncertainty_score":0.5775053},"labels":[],"label_agreement":null},{"id":"W4410869056","doi":"10.3390/v17060770","title":"The Spread of Endogenous Retroviruses in Populations Infected by Exogenous Viruses","year":2025,"lang":"en","type":"article","venue":"Viruses","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Population; Fixation (population genetics); Virulence; Genome; Endogenous retrovirus; Genetics; DNA; Gene","score_opus":0.025561142890215598,"score_gpt":0.32123517188165596,"score_spread":0.29567402899144035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410869056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868761,0.010004583,0.0016203511,0.00003054326,0.00020949928,0.00018948344,0.000060757007,0.000020363006,0.0009883533],"genre_scores_gemma":[0.9986376,0.0007650615,0.00014881018,0.0002558707,0.00003622801,0.000026672706,0.00002057617,0.000014713239,0.00009444941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991951,0.000043541226,0.00028163125,0.00018825856,0.00008133245,0.00021013596],"domain_scores_gemma":[0.9994693,0.000053075386,0.000054724245,0.00035122992,0.00004440461,0.000027275099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108399494,0.00012704021,0.00013630294,0.000071512055,0.000095726115,0.000019645186,0.00019630129,0.00009337543,0.000006906843],"category_scores_gemma":[0.00018556158,0.00010542237,0.000056712004,0.00022766329,0.0000744128,0.0000034193063,0.000085244144,0.000070383874,0.0000032781106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038427235,0.0000568154,0.058512546,0.0000142138515,0.000033866465,9.204608e-7,0.000031069478,0.00031722995,0.9373332,0.0002739975,0.0016604257,0.0017272681],"study_design_scores_gemma":[0.0002908407,0.00008614813,0.017070571,0.00002103832,0.00001774654,0.0000027418507,0.00005204533,0.000015139284,0.93012,0.00010701136,0.052099958,0.000116777024],"about_ca_topic_score_codex":0.00045156674,"about_ca_topic_score_gemma":0.0006968844,"teacher_disagreement_score":0.050439533,"about_ca_system_score_codex":0.000013447379,"about_ca_system_score_gemma":0.000061269115,"threshold_uncertainty_score":0.42989996},"labels":[],"label_agreement":null},{"id":"W4410901332","doi":"10.1038/s41551-025-01407-7","title":"Efficient and multiplexed somatic genome editing with Cas12a mice","year":2025,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Tobacco-Related Disease Research Program; National Cancer Institute; National Science Foundation; U.S. Department of Health and Human Services; National Institutes of Health; Canadian Institutes of Health Research; American Cancer Society","keywords":"Somatic cell; Genome; Computational biology; Biology; Multiplexing; Genome editing; Genetics; Computer science; Gene; Telecommunications","score_opus":0.0012808542422866507,"score_gpt":0.23416170018128132,"score_spread":0.23288084593899466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410901332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89449024,0.004804016,0.0994854,0.0002698892,0.00047631166,0.00019468782,0.000011730642,0.00007016093,0.00019755933],"genre_scores_gemma":[0.98921776,0.00002811204,0.010267383,0.00010172757,0.00024272563,0.000014295576,0.0000382385,0.000019655696,0.00007008952],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9991757,0.000006044519,0.00014659125,0.00027695077,0.00013843727,0.00025622424],"domain_scores_gemma":[0.99965113,0.000024018573,0.000019666944,0.00016117757,0.00003165931,0.000112370086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010643024,0.00016498653,0.00013890916,0.00011693015,0.000043690365,0.000019087076,0.00010758124,0.00027787735,0.0000033863264],"category_scores_gemma":[0.00015621769,0.00014046712,0.00003234385,0.000209365,0.000043653756,0.000001078812,0.000087063156,0.0002725556,8.9869525e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015197607,0.000025689686,0.00011955406,0.00020431203,0.00007299914,0.000011038013,0.000046295103,0.017975735,0.9802678,0.000057734884,0.00010265717,0.001100966],"study_design_scores_gemma":[0.0051877224,0.00053948164,0.02986081,0.00085317466,0.00020852302,0.00028549513,0.00039563532,0.44679594,0.3156566,0.000011236075,0.19867444,0.0015309539],"about_ca_topic_score_codex":0.0000037893224,"about_ca_topic_score_gemma":0.000002693828,"teacher_disagreement_score":0.6646112,"about_ca_system_score_codex":0.000015945017,"about_ca_system_score_gemma":0.000028797347,"threshold_uncertainty_score":0.57280827},"labels":[],"label_agreement":null},{"id":"W4410994202","doi":"10.1016/j.xcrm.2025.102157","title":"Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells","year":2025,"lang":"en","type":"article","venue":"Cell Reports Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"HORIZON EUROPE European Research Council; European Research Council; HORIZON EUROPE Framework Programme; H2020 European Research Council; Associazione Italiana per la Ricerca sul Cancro; Fondazione Telethon; Deutscher Akademischer Austauschdienst; Princess Margaret Cancer Foundation; Boehringer Ingelheim Fonds; New York Stem Cell Foundation","keywords":"CRISPR; Haematopoiesis; Stem cell; Genome editing; Senescence; Inflammation; Biology; Gene; Genetic enhancement; Cell biology; Immunology; Genetics","score_opus":0.006597038632800289,"score_gpt":0.26059121539882385,"score_spread":0.25399417676602354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410994202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901025,0.002838947,0.005291979,0.00031880362,0.0004440409,0.00021654995,0.000002366608,0.000013040133,0.0007717341],"genre_scores_gemma":[0.9987962,0.0004960204,0.00015440771,0.000052171352,0.00009515557,0.000009336575,0.000026340023,0.000009071656,0.0003612556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988561,0.00002915844,0.000528139,0.00029224748,0.00012894892,0.00016535183],"domain_scores_gemma":[0.9993001,0.00003006998,0.00024285568,0.00025496125,0.00011074993,0.00006124948],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032242172,0.0001395535,0.0002488168,0.000113905364,0.000025169078,0.0000032530313,0.000060728933,0.00010942781,0.000008704701],"category_scores_gemma":[0.0001353356,0.00012629955,0.000027434402,0.00017076958,0.00023596958,0.000003616805,0.000056773817,0.000085713174,3.6377043e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012484267,0.000012055582,0.011702767,0.00027955804,0.000011411727,0.00013638216,0.00022266273,0.00030735903,0.9867059,0.0000071876852,0.00023899914,0.0003632297],"study_design_scores_gemma":[0.00042161695,0.000056673554,0.0024802051,0.0003474145,0.000027181552,0.000072964714,0.0019950755,0.00019515952,0.9934616,0.00004062977,0.0008002362,0.00010124747],"about_ca_topic_score_codex":0.000054003034,"about_ca_topic_score_gemma":0.00003114226,"teacher_disagreement_score":0.0092225615,"about_ca_system_score_codex":0.000012956298,"about_ca_system_score_gemma":0.00006844835,"threshold_uncertainty_score":0.5150346},"labels":[],"label_agreement":null},{"id":"W4411006213","doi":"10.3389/fgeed.2025.1568072","title":"Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective","year":2025,"lang":"en","type":"review","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Genome editing; Perspective (graphical); Food security; Genome; Agriculture; Data science; Biology; Biotechnology; Engineering ethics; Computer science; Genetics; Gene; Engineering; Ecology","score_opus":0.04233057939127572,"score_gpt":0.33687630733980484,"score_spread":0.2945457279485291,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411006213","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016325037,0.99295276,0.0031415166,0.000071896844,0.0019254563,0.00066783366,0.00017279712,0.00001315769,0.000891335],"genre_scores_gemma":[0.00013432314,0.98487455,0.012500597,0.000030198473,0.0017037475,0.00023610027,0.00033442563,0.00004496961,0.00014111614],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977076,0.000053049393,0.0005456177,0.0009138259,0.0001822346,0.00059766363],"domain_scores_gemma":[0.9992701,0.0000516895,0.00019683325,0.0002444588,0.00013706172,0.00009989154],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007547032,0.0004062324,0.00083697774,0.0004106531,0.00014734665,0.00006283332,0.0004000759,0.0003073998,0.0000030746014],"category_scores_gemma":[0.00040110692,0.0004438947,0.0001341792,0.00020775564,0.00019807201,0.000012479819,0.00038511705,0.0002941857,2.9769916e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006709195,0.000024924977,0.00001513225,0.0030465291,0.0001332976,0.000010736927,0.0016120846,0.000029300289,0.00019338138,0.000049892282,0.00021397465,0.994664],"study_design_scores_gemma":[0.0003748744,0.00004786815,0.00010971375,0.002548742,0.00008903494,0.0000060424463,0.010051291,0.00004148649,0.000055139073,0.00013165845,0.9860014,0.00054276414],"about_ca_topic_score_codex":0.000009583571,"about_ca_topic_score_gemma":0.000024372295,"teacher_disagreement_score":0.99412125,"about_ca_system_score_codex":0.0003743521,"about_ca_system_score_gemma":0.0007580302,"threshold_uncertainty_score":0.9998013},"labels":[],"label_agreement":null},{"id":"W4411216162","doi":"10.1039/9781839169779-00444","title":"Negotiating the Regulatory Pathway","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Negotiation; Political science; Law","score_opus":0.005484961423305014,"score_gpt":0.24211528066821975,"score_spread":0.23663031924491473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411216162","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011028256,0.006484746,0.005939039,0.000095593954,0.00042126552,0.00015722582,0.00001605375,0.000022601062,0.98675317],"genre_scores_gemma":[0.01221515,0.00032249614,0.00024716492,0.0002860976,0.00047307898,0.0000070598985,0.00008445953,0.000031356456,0.98633313],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993667,0.0000051051165,0.00015426039,0.0002508179,0.00009134471,0.00013175748],"domain_scores_gemma":[0.9993747,0.000012203929,0.000042429456,0.0005001322,0.00004024,0.00003030551],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008064644,0.0001876612,0.00011696426,0.000024701974,0.00006057734,0.000021617836,0.00018780127,0.0002551399,0.00008666126],"category_scores_gemma":[0.000016915528,0.00013792161,0.000116110765,0.0000084835765,0.000037845864,3.499647e-7,0.00015119216,0.00014414113,0.000014228454],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034069657,0.000019223944,0.000040585775,0.00022629835,0.0007280968,0.000013373278,0.000068300615,0.0038725138,0.09225911,0.46350896,0.35142827,0.08780119],"study_design_scores_gemma":[0.0000757917,0.000028010774,0.000025861364,0.000032706306,0.000023432909,0.000004866073,0.000010531973,0.00009119494,0.012983602,0.0003463582,0.98617977,0.00019785522],"about_ca_topic_score_codex":0.0000037663747,"about_ca_topic_score_gemma":0.000010234868,"teacher_disagreement_score":0.6347515,"about_ca_system_score_codex":0.0000075215353,"about_ca_system_score_gemma":0.000072300776,"threshold_uncertainty_score":0.562428},"labels":[],"label_agreement":null},{"id":"W4411235406","doi":"10.3390/ijms26125647","title":"In Vitro Correction of Point Mutations in the DYSF Gene Using Prime Editing","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Jain Foundation","keywords":"Point mutation; Gene; Dysferlin; Genetics; Genome editing; Mutation; Biology; Molecular biology; Computational biology; CRISPR","score_opus":0.008111263396811886,"score_gpt":0.33130669539349183,"score_spread":0.32319543199667994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411235406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9325989,0.00047634335,0.06537203,0.00042335608,0.0008166996,0.00003393508,0.0000011278008,4.4785284e-7,0.0002771654],"genre_scores_gemma":[0.99679476,0.000021705873,0.0029585585,0.00013594115,0.000077362994,8.379449e-7,0.000001440215,0.0000016358495,0.000007732627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993781,0.000038605733,0.00023840903,0.0000727421,0.00020651415,0.00006564411],"domain_scores_gemma":[0.99970526,0.000020061698,0.0001049476,0.00004522392,0.00011566903,0.00000887202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051077636,0.000041346426,0.00005891291,0.00020485772,0.000017623885,0.000020180632,0.00028010487,0.000024490593,0.0000017119199],"category_scores_gemma":[0.00015450917,0.000033126675,0.000046577272,0.000186515,0.00005604002,0.000009353676,0.000033066608,0.000064149135,7.804514e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014045796,0.000024640058,0.0005875901,0.0000013173325,0.000012393554,0.000012886113,0.0001129887,0.0471802,0.95045,0.000038955342,0.000014272412,0.0015506885],"study_design_scores_gemma":[0.0002097581,0.00003906073,0.0016864121,0.000037051745,0.0000051597644,0.00007201487,0.0004744508,0.0065921396,0.99052554,0.00020756503,0.00012010887,0.00003070882],"about_ca_topic_score_codex":0.00003408189,"about_ca_topic_score_gemma":0.000011657675,"teacher_disagreement_score":0.06419589,"about_ca_system_score_codex":0.000018999077,"about_ca_system_score_gemma":0.00009727958,"threshold_uncertainty_score":0.13508666},"labels":[],"label_agreement":null},{"id":"W4411239203","doi":"10.1093/toxsci/kfaf083","title":"Chemical-induced heart defects using a transgenic zebrafish model","year":2025,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; RIKEN","keywords":"Zebrafish; Transgene; Genetically modified mouse; Cell biology; Chemistry; Biology; Computational biology; Biochemistry; Gene","score_opus":0.038489036686924896,"score_gpt":0.3639345363610139,"score_spread":0.32544549967408903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411239203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97407836,0.00023583355,0.02301871,0.00021747327,0.00008628489,0.0001123632,0.000001550921,0.000023466182,0.0022259892],"genre_scores_gemma":[0.99517256,0.000008754943,0.0039586793,0.0007121938,0.000039428163,0.0000099388535,0.0000015578305,0.0000034016862,0.00009346282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991167,0.000021751935,0.00012710353,0.00034499346,0.000105801715,0.0002836343],"domain_scores_gemma":[0.9997596,0.00001672505,0.00001525974,0.00012326949,0.000018325192,0.000066819586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020325894,0.000106958585,0.00011876859,0.000033059787,0.000120303666,0.000031594947,0.00023445711,0.0001411216,0.000018522296],"category_scores_gemma":[0.00008545774,0.000084986415,0.00008597907,0.00023559203,0.00013809135,0.0000029349094,0.00008521003,0.00007112912,0.000001912324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007358255,0.000032059237,0.00025765665,0.0000049085966,0.0000050538397,3.0624727e-7,0.000006872552,0.008482349,0.99045634,0.00021062,0.000130099,0.00040636002],"study_design_scores_gemma":[0.0001661702,0.00011936264,0.00041373385,0.000008372478,0.000010392078,0.000003360126,0.000018975226,0.026810544,0.9713995,0.00047615933,0.00044164882,0.00013179543],"about_ca_topic_score_codex":0.0000035618532,"about_ca_topic_score_gemma":0.000004444869,"teacher_disagreement_score":0.021094255,"about_ca_system_score_codex":0.000012562781,"about_ca_system_score_gemma":0.00008819945,"threshold_uncertainty_score":0.34656453},"labels":[],"label_agreement":null},{"id":"W4411293183","doi":"10.1101/2025.06.12.659409","title":"Planetary-scale metagenomic search reveals new patterns of CRISPR targeting","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"CRISPR; Metagenomics; Scale (ratio); Computational biology; Biology; Computer science; Evolutionary biology; Geography; Genetics; Cartography; Gene","score_opus":0.009871112128427641,"score_gpt":0.25639087054136295,"score_spread":0.2465197584129353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411293183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9305244,0.006752797,0.060310118,0.000081984756,0.00086296507,0.0005761108,0.0007923988,0.0000751734,0.000024029088],"genre_scores_gemma":[0.9877469,0.00094337604,0.010287858,0.00009549816,0.0006927488,0.000033717657,0.000009114323,0.00008083618,0.000109937806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99749064,0.00010627837,0.0006412536,0.00094824494,0.0002658644,0.00054772256],"domain_scores_gemma":[0.9980358,0.000027058424,0.00022032455,0.001237314,0.00022651193,0.00025299488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050242885,0.0005085234,0.0006046287,0.00019788761,0.00006923496,0.000058544887,0.0006926995,0.000582146,0.00005356409],"category_scores_gemma":[0.00009762247,0.0005824139,0.00024774027,0.00016667525,0.000044629523,0.000004752639,0.0008046655,0.000502156,0.0000111186855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031477142,0.000042523578,0.015551792,0.0007378582,0.00026193942,0.000007697883,0.000011243852,0.0029279427,0.97899437,0.000022458673,0.0014052308,0.0000054480342],"study_design_scores_gemma":[0.00038894019,0.00006433365,0.033998426,0.0002678148,0.00014179689,1.9839748e-8,0.0000060450157,0.00019909513,0.95891684,9.783853e-7,0.005449325,0.0005664027],"about_ca_topic_score_codex":0.00024889887,"about_ca_topic_score_gemma":0.000009131191,"teacher_disagreement_score":0.057222493,"about_ca_system_score_codex":0.000049598693,"about_ca_system_score_gemma":0.000533584,"threshold_uncertainty_score":0.99966276},"labels":[],"label_agreement":null},{"id":"W4411293843","doi":"10.1016/b978-0-443-22300-6.00055-3","title":"The path towards precision medicine: Next generation biotherapeutics and delivery strategies across the blood–brain barrier for the treatment of neurodegenerative diseases","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; University of Ottawa","funders":"","keywords":"Blood–brain barrier; Medicine; Neuroscience; Internal medicine; Psychology; Central nervous system","score_opus":0.0208347925852975,"score_gpt":0.3096408415595196,"score_spread":0.2888060489742221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411293843","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.056764465,0.83983105,0.009256354,0.0038850997,0.0032449074,0.009385865,0.00261838,0.00006103591,0.07495281],"genre_scores_gemma":[0.08567256,0.10157555,0.00029138016,0.0008750254,0.0026162595,0.0005117469,0.00031364616,0.00012394357,0.8080199],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99903643,0.00004097211,0.00028661414,0.00031811305,0.00014265068,0.00017519161],"domain_scores_gemma":[0.99898344,0.00021869846,0.00011876245,0.00050954235,0.0001293245,0.000040233423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015638262,0.0003027168,0.00023330987,0.000016621641,0.00037692327,0.000083533545,0.00020816957,0.00015909514,0.000003537888],"category_scores_gemma":[0.000032874854,0.00014096529,0.00016398165,0.000010188057,0.0003387852,0.000002478063,0.000065289074,0.000074908596,1.2739652e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006225513,0.000010041677,0.0000023717353,0.000032716554,0.0003858437,6.257225e-7,0.0005729847,0.00010631057,0.045538306,0.000818902,0.0003469168,0.95212275],"study_design_scores_gemma":[0.00056334777,0.00087414426,0.000042746327,0.00006383287,0.0004786081,0.0000037145876,0.0002579531,0.0007077906,0.028152943,0.00044286068,0.96821785,0.00019419815],"about_ca_topic_score_codex":0.0000025116256,"about_ca_topic_score_gemma":0.000099788595,"teacher_disagreement_score":0.96787095,"about_ca_system_score_codex":0.000011087429,"about_ca_system_score_gemma":0.00014057236,"threshold_uncertainty_score":0.5748398},"labels":[],"label_agreement":null},{"id":"W4411294081","doi":"10.1016/b978-0-443-22300-6.00044-9","title":"Harnessing CRISPR/Cas systems for tailored therapeutic interventions in molecular medicine: Advancements in precision medicine and enhanced patient care","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"CRISPR; Psychological intervention; Precision medicine; Medicine; Intensive care medicine; Biology; Nursing; Pathology; Genetics","score_opus":0.015558865842280608,"score_gpt":0.33094793771840936,"score_spread":0.31538907187612875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411294081","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0042282133,0.50875807,0.10118677,0.00018723533,0.0023060753,0.0059891623,0.000086361906,0.000038821137,0.37721932],"genre_scores_gemma":[0.79091513,0.0053686067,0.0007587905,0.0003013294,0.0003272015,0.00081312604,0.00062830077,0.00015529527,0.2007322],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983764,0.00003299012,0.0006548409,0.00053634646,0.00016530928,0.00023405437],"domain_scores_gemma":[0.99926835,0.00003411381,0.00016066617,0.00035571848,0.000121192534,0.000059947968],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016339771,0.0003452116,0.0005085213,0.00026612042,0.000040564035,0.000012975403,0.00014468496,0.00026922266,0.000007772165],"category_scores_gemma":[0.000062501116,0.00031248407,0.00011592708,0.000024890447,0.00008779842,0.0000025215109,0.000113400834,0.00017907949,3.9990056e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008508106,0.000011440566,0.00001597997,0.001501193,0.000089560184,0.000008953048,0.00089193427,0.00028767614,0.047270127,0.00025999176,0.000040333245,0.94953775],"study_design_scores_gemma":[0.00882483,0.0038195325,0.00020331377,0.050190374,0.0006671017,0.000020580494,0.0024816217,0.00067595317,0.06976508,0.0029979215,0.85848695,0.0018667385],"about_ca_topic_score_codex":0.0000049375903,"about_ca_topic_score_gemma":0.00009539019,"teacher_disagreement_score":0.947671,"about_ca_system_score_codex":0.00006970208,"about_ca_system_score_gemma":0.00004499516,"threshold_uncertainty_score":0.9999327},"labels":[],"label_agreement":null},{"id":"W4411310156","doi":"10.1007/978-1-0716-4615-1_24","title":"Screening for Host Proteins with Pro- and Antiviral Activity via High-Throughput CRISPR","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Host (biology); Throughput; Computational biology; High-throughput screening; Host factors; Biology; Computer science; Virology; Genetics; Gene; Virus; Operating system","score_opus":0.01343768750624507,"score_gpt":0.41480077567765333,"score_spread":0.40136308817140826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411310156","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15181704,0.0007045087,0.8464059,0.00019318811,0.00008650629,0.0006415203,0.00001047192,0.000014408219,0.0001264524],"genre_scores_gemma":[0.38517776,0.0000274369,0.6143577,0.00013136976,0.00003126851,0.00016403497,0.00001962833,0.00001802572,0.000072793206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865776,0.0002455267,0.00017147769,0.0005503281,0.00003751124,0.0003373833],"domain_scores_gemma":[0.9995062,0.000049250564,0.00004953124,0.00031346406,0.00004572708,0.00003583867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005204902,0.00021279015,0.00027461143,0.000107186126,0.000059815662,0.000015515961,0.00013926717,0.00023984343,0.0000012491395],"category_scores_gemma":[0.00016584685,0.0001915156,0.000056662022,0.00016399047,0.00013451527,0.0000030644235,0.00015646056,0.00013955138,1.3083923e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017823331,0.000033548484,0.002145471,0.00005806728,0.000069759626,0.0000032856537,0.000014384312,0.000097097596,0.95236313,0.0005839247,0.000010900254,0.044442195],"study_design_scores_gemma":[0.0010102002,0.00052474806,0.0032500855,0.000029746758,0.000028702463,0.000007741955,0.000016091342,0.00080316357,0.98978597,0.0007967945,0.003511374,0.00023539111],"about_ca_topic_score_codex":0.00006153657,"about_ca_topic_score_gemma":0.000044620672,"teacher_disagreement_score":0.23336071,"about_ca_system_score_codex":0.000010382798,"about_ca_system_score_gemma":0.000042996107,"threshold_uncertainty_score":0.78097796},"labels":[],"label_agreement":null},{"id":"W4411310160","doi":"10.1007/978-1-0716-4615-1_22","title":"The Application of Base-Editing Technology to Investigate Virus–Host Interactions and Antiviral Therapeutic Strategies","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Host (biology); Base (topology); Virology; Virus; Biology; Computer science; Genetics; Mathematics","score_opus":0.011551322993819987,"score_gpt":0.43241751570709475,"score_spread":0.42086619271327474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411310160","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14810544,0.001647694,0.8489627,0.00066020526,0.00011304589,0.00017083957,0.0000035394742,0.000009535587,0.00032695945],"genre_scores_gemma":[0.8133756,0.00010919564,0.18616015,0.00020835575,0.000019598905,0.00008024757,0.000007576196,0.00000927622,0.000029987534],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913424,0.00019087466,0.00022043935,0.00025806724,0.00002273931,0.00017361363],"domain_scores_gemma":[0.99953496,0.00007086395,0.00004825248,0.00028296688,0.00004338747,0.000019543471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004411653,0.00010800042,0.0001385261,0.00015248476,0.00005486899,0.000012158172,0.00016993177,0.00012407586,5.263074e-7],"category_scores_gemma":[0.00023286772,0.0000904041,0.000032104414,0.0003020949,0.00018968778,0.0000018657672,0.00015429949,0.0001201237,3.7104553e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011500536,0.000008984637,0.0016959126,0.000010360945,0.000027821738,3.199e-7,0.000019606512,0.00014052952,0.9392819,0.013744192,0.0000054588972,0.04505346],"study_design_scores_gemma":[0.00012693975,0.00008014974,0.001038151,0.000012670052,0.000011281827,0.0000029263158,0.0002636524,0.0006772015,0.97878337,0.007429638,0.011493385,0.00008063199],"about_ca_topic_score_codex":0.000031388343,"about_ca_topic_score_gemma":0.00012276592,"teacher_disagreement_score":0.66527015,"about_ca_system_score_codex":0.000007461532,"about_ca_system_score_gemma":0.000035920853,"threshold_uncertainty_score":0.3686572},"labels":[],"label_agreement":null},{"id":"W4411310226","doi":"10.1007/978-1-0716-4615-1_10","title":"CRISPR-Mediated Viral Gene Knock-In for Studying Viral–Host Interactions","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"CRISPR; Host (biology); Biology; Genome editing; Virology; Gene; Genetics; Computational biology","score_opus":0.016863255704768453,"score_gpt":0.4523472176038174,"score_spread":0.435483961899049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411310226","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14474124,0.001722902,0.8518935,0.00019063613,0.0005693801,0.00041684147,0.000018729068,0.000016284846,0.0004305118],"genre_scores_gemma":[0.39565912,0.00015122278,0.60252446,0.00068809727,0.00009197398,0.00034859474,0.00018052447,0.00003695491,0.00031902804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982273,0.00036926242,0.0004149188,0.000537628,0.000036915746,0.00041396983],"domain_scores_gemma":[0.9993321,0.00013995777,0.000053039697,0.0003770424,0.000053913456,0.000043986267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071808486,0.0002201342,0.00030517796,0.00030305938,0.00004552791,0.000014030424,0.0002540592,0.00024676727,0.000008637874],"category_scores_gemma":[0.0006319995,0.00023474074,0.00013294697,0.00025274107,0.00006184194,0.0000026644605,0.00018559869,0.00020589701,0.0000018820465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006991503,0.00007075593,0.0032159265,0.000023149965,0.00005691916,0.000005395468,0.000035601028,0.0006191875,0.9886701,0.0004965632,0.000076963675,0.0066595124],"study_design_scores_gemma":[0.0011846797,0.00019058734,0.002106403,0.000024305342,0.000022904958,0.0000057097977,0.0000793582,0.0017737506,0.9677733,0.0012447805,0.025329225,0.0002649748],"about_ca_topic_score_codex":0.00004681836,"about_ca_topic_score_gemma":0.00011144483,"teacher_disagreement_score":0.25091788,"about_ca_system_score_codex":0.00004270835,"about_ca_system_score_gemma":0.000060699796,"threshold_uncertainty_score":0.95724493},"labels":[],"label_agreement":null},{"id":"W4411326375","doi":"10.3389/fpls.2025.1623554","title":"Editorial: Evolution of crop genomes and epigenomes, volume II","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"Natural Science Foundation of Chongqing; Vetenskapsrådet","keywords":"Genome; Crop; Biology; Computational biology; Evolutionary biology; Computer science; Genetics; Ecology; Gene","score_opus":0.0021347953338171884,"score_gpt":0.23664127275097593,"score_spread":0.23450647741715874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411326375","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012659964,0.012916201,0.00829708,0.000011164581,0.97671556,0.00014478198,0.0004310759,0.0000069001276,0.00021122354],"genre_scores_gemma":[0.004709959,0.0039055005,0.0036508974,0.000003623974,0.9851471,0.000015340896,0.00029215738,0.000016286935,0.0022591413],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984515,0.00001771305,0.00026360963,0.0005340882,0.00042095874,0.00031216416],"domain_scores_gemma":[0.9993743,0.000013124181,0.00009746134,0.00031260535,0.00013444701,0.000068067326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005350041,0.00018697392,0.00028090933,0.00029640668,0.00011027827,0.000024486451,0.00046704718,0.0004321013,0.0000012125398],"category_scores_gemma":[0.0003964536,0.00019555177,0.000042153766,0.000284148,0.00034341044,0.00000595403,0.00032772342,0.00022155172,2.6518921e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030029716,0.000013258639,0.00082777435,0.000078343546,0.000012873145,7.6607745e-7,0.00004323787,0.00021112536,0.011829443,0.0000055622486,0.98642486,0.00052269315],"study_design_scores_gemma":[0.00022102088,0.000117506854,0.00022638575,0.00006897524,0.000016015434,6.8725626e-7,0.00004059935,0.00027756684,0.002736375,0.000053418007,0.996039,0.00020246113],"about_ca_topic_score_codex":0.00007477494,"about_ca_topic_score_gemma":0.00002402453,"teacher_disagreement_score":0.009614096,"about_ca_system_score_codex":0.00010153411,"about_ca_system_score_gemma":0.0008328725,"threshold_uncertainty_score":0.79743695},"labels":[],"label_agreement":null},{"id":"W4411363845","doi":"10.47854/chfbwy91","title":"Transgenre","year":2025,"lang":"en","type":"article","venue":"Anthropen","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Psychology","score_opus":0.005563277654524265,"score_gpt":0.34367969609815696,"score_spread":0.3381164184436327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411363845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8085821,0.004094754,0.09288288,0.0010627934,0.00059502805,0.00025208457,0.000008816741,0.000033119053,0.092488386],"genre_scores_gemma":[0.99427646,0.00019968845,0.00037591465,0.00024948965,0.000052225274,0.0000063133843,0.000014703008,0.0000054804254,0.004819735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997068,0.000005811847,0.000056737746,0.0001176571,0.000024546765,0.00008841345],"domain_scores_gemma":[0.9998091,0.0000017160608,0.000004885943,0.00015427762,0.000013092118,0.000016914451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000033370616,0.00004976109,0.000046200017,0.000014706832,0.000033782668,0.000008928081,0.000093572264,0.000038650123,0.000054534223],"category_scores_gemma":[0.000007955023,0.00004724452,0.000031129846,0.00004725923,0.000024996165,5.908269e-7,0.000033215296,0.000023753148,0.000014338122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023281544,0.000029783107,0.002129421,0.000023135191,0.000059629223,0.0000029034911,0.00003653957,0.00020931319,0.9430705,0.0005852451,0.0272405,0.02658979],"study_design_scores_gemma":[0.00021630414,0.000040129526,0.003735047,0.000009041786,0.0000081677135,0.0000022245633,0.000055763747,0.000027475417,0.6772262,0.00003755055,0.31856257,0.00007953278],"about_ca_topic_score_codex":0.000013534004,"about_ca_topic_score_gemma":0.000022236027,"teacher_disagreement_score":0.29132208,"about_ca_system_score_codex":0.0000018156306,"about_ca_system_score_gemma":0.000019204153,"threshold_uncertainty_score":0.19265758},"labels":[],"label_agreement":null},{"id":"W4411407051","doi":"10.1139/cjm-2025-0022","title":"When DNA writing is free: open tools and strategies to accelerate the bioeconomy","year":2025,"lang":"en","type":"review","venue":"Canadian Journal of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Positive Living Society of British Columbia; Global Institute for Water Security; University of Saskatchewan","funders":"","keywords":"Synthetic biology; Biotechnology; Biology; Computational biology","score_opus":0.029364410046694864,"score_gpt":0.32968626442788246,"score_spread":0.3003218543811876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411407051","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003246578,0.9966728,0.0002653505,0.0006711187,0.0003373314,0.0003680188,0.0005071283,0.0000010513663,0.00085253094],"genre_scores_gemma":[0.00042269664,0.9965185,0.00062728307,0.0012323087,0.00037094366,0.000017542381,0.000097202275,0.000027589354,0.0006859221],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99884236,0.00009111222,0.0004905279,0.0002490478,0.000014021762,0.00031295294],"domain_scores_gemma":[0.9991011,0.00005049405,0.00018757427,0.00034644664,0.00009011033,0.00022428093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033137284,0.00024579174,0.0006687142,0.00016305315,0.00010986275,0.00029862885,0.0011921548,0.00028772664,0.00006822866],"category_scores_gemma":[0.000088552704,0.00018123929,0.00016454731,0.00007289548,0.000085814085,0.0000071436452,0.000263436,0.0002524747,0.000004267501],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012678368,0.0000072389976,0.000025980911,0.0024999748,0.0008796141,0.000059497343,0.00032344073,0.000020444482,0.008619053,0.00023382703,0.22172347,0.7655948],"study_design_scores_gemma":[0.00013445389,0.00010022078,0.0000045121064,0.0011760971,0.00012388093,0.00050258136,0.00012845956,6.6231124e-8,0.00059356465,0.000035831454,0.9970095,0.00019082906],"about_ca_topic_score_codex":0.00030370787,"about_ca_topic_score_gemma":0.006327406,"teacher_disagreement_score":0.775286,"about_ca_system_score_codex":0.000037775964,"about_ca_system_score_gemma":0.002410003,"threshold_uncertainty_score":0.7390724},"labels":[],"label_agreement":null},{"id":"W4411466886","doi":"10.1021/acssynbio.5c00232","title":"The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology","year":2025,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; National Institute of Genetics; Core Research for Evolutional Science and Technology; University of Manchester; Royal Society","keywords":"Synthetic biology; Biology; Engineering ethics; Engineering; Computational biology","score_opus":0.00834408828808776,"score_gpt":0.3089090238552781,"score_spread":0.30056493556719033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411466886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81613404,0.0075545884,0.16013423,0.0037940128,0.002940088,0.0007007639,0.00014077059,0.00013221186,0.008469301],"genre_scores_gemma":[0.9959939,0.0006671459,0.0016587853,0.0005693399,0.00029189631,0.00012598721,0.00006569348,0.00003074476,0.0005965016],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99722147,0.00020432087,0.0005834962,0.0009350955,0.000066271015,0.0009893614],"domain_scores_gemma":[0.9983009,0.0002553796,0.00010121504,0.0010122363,0.00015805374,0.00017217759],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005028993,0.000469814,0.00046542345,0.00013412564,0.0002879689,0.000052201518,0.00091221556,0.00093470205,0.000050028717],"category_scores_gemma":[0.0007342877,0.0003694444,0.00018273383,0.00033102575,0.00035196202,0.0000028527027,0.0006287402,0.00041577674,0.00006708043],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014345588,0.000072545066,0.018653205,0.0000377232,0.0004922765,0.0000025196798,0.00008331676,0.00062508404,0.7747619,0.11354959,0.00087953603,0.09069883],"study_design_scores_gemma":[0.001499624,0.0012827425,0.0060407766,0.00019020654,0.00024444878,0.00007124274,0.00041976979,0.0013841983,0.30555508,0.01098912,0.67070436,0.001618419],"about_ca_topic_score_codex":0.00012154848,"about_ca_topic_score_gemma":0.00017873029,"teacher_disagreement_score":0.66982484,"about_ca_system_score_codex":0.000052220963,"about_ca_system_score_gemma":0.00015975635,"threshold_uncertainty_score":0.9998757},"labels":[],"label_agreement":null},{"id":"W4411550317","doi":"10.1007/978-1-0716-4654-0_14","title":"CRISPR-Cas9-Guided Genetic Manipulation of Patient-Derived Brain Tumor Cells","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Juravinski Cancer Centre; University of Toronto; McMaster University; McMaster University Medical Centre; Discovery Centre","funders":"","keywords":"CRISPR; Genome editing; Cas9; Computational biology; Biology; Neuroscience; Genetics; Computer science; Gene","score_opus":0.013307841767172233,"score_gpt":0.40410455782177723,"score_spread":0.390796716054605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411550317","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.356044,0.0012183136,0.6418806,0.00006921123,0.00025278298,0.00020441406,0.000005733438,0.000008566786,0.00031640305],"genre_scores_gemma":[0.41152102,0.000049344184,0.58768827,0.00055413577,0.000026195177,0.000039169463,0.00004173323,0.000022999158,0.000057106183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981589,0.0005297389,0.0005020803,0.00044957647,0.00005762613,0.00030211534],"domain_scores_gemma":[0.9992373,0.000064996755,0.000105274834,0.0004760877,0.00007225759,0.000044059594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039799232,0.00020608908,0.0002999831,0.00020206797,0.000025245892,0.0000067553106,0.00022610751,0.00021937292,0.00001725508],"category_scores_gemma":[0.00035920317,0.0002178161,0.00012612402,0.00025493623,0.0000916682,0.0000013772167,0.00018525888,0.00011524783,0.0000014638098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028767638,0.00003814564,0.0013737116,0.000043271637,0.00004349487,0.000007181338,0.00003479427,0.0035070297,0.9851877,0.00034605266,0.00015305037,0.009236804],"study_design_scores_gemma":[0.0004827673,0.00017731261,0.001575245,0.000020412639,0.00001978099,0.000008828962,0.00004258922,0.0007723938,0.990721,0.0013707145,0.00461766,0.00019130817],"about_ca_topic_score_codex":0.000041835687,"about_ca_topic_score_gemma":0.000012315539,"teacher_disagreement_score":0.055477034,"about_ca_system_score_codex":0.00001853828,"about_ca_system_score_gemma":0.000056088687,"threshold_uncertainty_score":0.8882283},"labels":[],"label_agreement":null},{"id":"W4411582013","doi":"10.1016/j.jcyt.2025.06.010","title":"Advancing gene-editing platforms to improve the viability of rare-disease therapeutics: key insights from a 2024 Scientific Exchange hosted by ARM, ISCT, and Danaher","year":2025,"lang":"en","type":"article","venue":"Cytotherapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Society for Cellular Therapy","funders":"National Institute of Allergy and Infectious Diseases; U.S. Food and Drug Administration; National Institutes of Health; Institut des Sciences du Cerveau de Toulouse; CSL Behring; National Brain Tumor Society","keywords":"Genome editing; Key (lock); Computational biology; Rare disease; Gene; Disease; Medicine; Biology; Computer science; CRISPR; Genetics; Pathology; Operating system","score_opus":0.005161849209960979,"score_gpt":0.2685198984983852,"score_spread":0.2633580492884242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411582013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9703459,0.013408308,0.014864412,0.00025688298,0.00044696798,0.0004147214,0.000118769225,0.000013171886,0.00013083682],"genre_scores_gemma":[0.9973335,0.00022468036,0.0005078566,0.0007217536,0.00015096273,0.000049772603,0.00005803197,0.000022145163,0.0009312501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903136,0.000021719794,0.00020533352,0.00042172166,0.000112708825,0.00020713097],"domain_scores_gemma":[0.99926627,0.000032875585,0.000049378526,0.00049209653,0.00006956675,0.00008981847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014762027,0.00016607568,0.00015099075,0.00005135454,0.000110327404,0.00005298693,0.00019188886,0.00007478147,0.000023909526],"category_scores_gemma":[0.000034769215,0.00012206019,0.000064111344,0.00016296678,0.000108501474,0.0000063623465,0.000089896166,0.000076324875,0.0000011782216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009407635,0.000040313036,0.001226377,0.00003616064,0.00007987966,5.911585e-7,0.0005603474,0.00006635132,0.98424715,0.000011837954,0.00091977697,0.012717121],"study_design_scores_gemma":[0.00064164976,0.00011549907,0.0031658572,0.00003723263,0.00003235447,3.882757e-7,0.00028098037,0.00077037676,0.92275673,0.00040619448,0.07161329,0.00017943974],"about_ca_topic_score_codex":0.000028405677,"about_ca_topic_score_gemma":0.00007280377,"teacher_disagreement_score":0.070693515,"about_ca_system_score_codex":0.000016529726,"about_ca_system_score_gemma":0.00005448663,"threshold_uncertainty_score":0.497747},"labels":[],"label_agreement":null},{"id":"W4411642213","doi":"10.1146/annurev-virology-092623-111016","title":"CRISPR-Cas in the Cheese Industry","year":2025,"lang":"en","type":"review","venue":"Annual Review of Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Biology; Streptococcus thermophilus; Cas9; Dairy industry; Genome editing; Function (biology); Computational biology; Bacteria; Biotechnology; Microbiology; Genetics; Gene; Lactic acid; Food science","score_opus":0.013542237007199294,"score_gpt":0.4108074305440037,"score_spread":0.3972651935368044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411642213","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000014739695,0.9970872,0.000063510015,0.00017694922,0.00015502745,0.0006286402,0.00008404146,0.0000036088695,0.0017863284],"genre_scores_gemma":[0.000055784505,0.9977655,0.000041633095,0.0013153326,0.00016313906,0.00015612529,0.00019656261,0.000019512961,0.00028642832],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998216,0.00034762145,0.00069079205,0.0003682386,0.00011121241,0.00026616876],"domain_scores_gemma":[0.99892086,0.00007769455,0.00019841296,0.0007141084,0.000054398566,0.000034527853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006789146,0.00031337916,0.0012255294,0.00009465665,0.000018522016,0.0000037909192,0.0006741009,0.00079518824,0.0000351977],"category_scores_gemma":[0.0005118938,0.00021156187,0.00042605685,0.00030570812,0.000080688136,0.0000014765351,0.00020615142,0.0006401751,0.000011210338],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004227534,0.00006880822,0.0000068332274,0.14225478,0.00010905152,0.000015852755,0.000035450736,0.0000017337074,0.000032354772,0.00011363511,0.018483993,0.83887327],"study_design_scores_gemma":[0.000072826646,0.00011699562,0.000037284502,0.024071151,0.0002882574,0.00005419491,0.000018187997,1.2613621e-7,0.000022608465,0.000007720248,0.97514653,0.00016411388],"about_ca_topic_score_codex":0.000009975237,"about_ca_topic_score_gemma":0.000012200596,"teacher_disagreement_score":0.95666254,"about_ca_system_score_codex":0.000010134591,"about_ca_system_score_gemma":0.00022610306,"threshold_uncertainty_score":0.8627243},"labels":[],"label_agreement":null},{"id":"W4411758006","doi":"10.1101/2025.06.26.661544","title":"Interpreting Attention Mechanisms in Genomic Transformer Models: A Framework for Biological Insights","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Ontario Genomics","keywords":"Computational biology; Transformer; Computer science; Biology; Engineering","score_opus":0.014152144995371537,"score_gpt":0.26305168555103137,"score_spread":0.24889954055565983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411758006","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4294878,0.0016401439,0.56751305,0.000039287715,0.0005304366,0.0006282914,0.00010277855,0.000050025774,0.000008205529],"genre_scores_gemma":[0.94293684,0.0006807773,0.055451985,0.00015696036,0.00021667534,0.0004890513,0.0000037164702,0.00005928107,0.000004691721],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978893,0.0000649092,0.00050199445,0.0009696665,0.00011246613,0.00046166088],"domain_scores_gemma":[0.99893934,0.000038026814,0.00013100843,0.00064029684,0.00014371019,0.00010761324],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032429566,0.00045497264,0.00042760264,0.000208676,0.00007248841,0.00006701884,0.00042965214,0.0010429284,0.000004558851],"category_scores_gemma":[0.00013568516,0.0004808917,0.0002551022,0.00016848571,0.00004328259,0.000006325661,0.00024291285,0.00047003996,0.0000023868076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008057549,0.000065892025,0.00025653312,0.00026223037,0.00009873293,0.000003153218,0.000015589443,0.0032804084,0.9914457,0.004460771,0.00002066499,0.000009720723],"study_design_scores_gemma":[0.0009438681,0.00023469323,0.0050159106,0.0011627629,0.000101283345,2.7092707e-8,0.00001883116,0.015293204,0.9729906,0.0010029052,0.0019695268,0.0012664252],"about_ca_topic_score_codex":0.000011897523,"about_ca_topic_score_gemma":0.000005049062,"teacher_disagreement_score":0.5134491,"about_ca_system_score_codex":0.00009666295,"about_ca_system_score_gemma":0.00018293437,"threshold_uncertainty_score":0.99976426},"labels":[],"label_agreement":null},{"id":"W4411891439","doi":"10.1038/s41467-025-61003-w","title":"Genetically encoded affinity reagents are a toolkit for visualizing and manipulating endogenous protein function in vivo","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; Yale University; National Institutes of Health; National Human Genome Research Institute","keywords":"Computational biology; Function (biology); Endogeny; In vivo; Computer science; Biology; Protein function; Cell biology; Chemistry; Genetics; Biochemistry; Gene","score_opus":0.027893638337364784,"score_gpt":0.34279091677769574,"score_spread":0.31489727844033094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411891439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94487524,0.014218107,0.036124792,0.0006242474,0.00013471305,0.00116816,0.000036507237,0.000037778114,0.0027804275],"genre_scores_gemma":[0.9866708,0.00022195194,0.012521568,0.00017016633,0.00003159825,0.00018030999,0.00005693487,0.000012121527,0.00013456037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993826,0.000048198617,0.000179639,0.0001991847,0.000047445636,0.00014293697],"domain_scores_gemma":[0.99921304,0.000044703866,0.000044868455,0.0005945072,0.00007386183,0.0000289928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016791787,0.00009964853,0.0001009442,0.00006635086,0.0001462925,0.00002496411,0.00024443166,0.0002242335,0.0000017247638],"category_scores_gemma":[0.00026340372,0.0001104937,0.000038970218,0.00012728412,0.000031112402,0.0000029918524,0.00022876648,0.00021323713,2.6044088e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044975954,0.000074334646,0.0059472537,0.00005759228,0.000036267367,3.1243061e-7,0.00004612113,0.00016747811,0.98836887,0.0025206637,0.00020383007,0.0025323078],"study_design_scores_gemma":[0.0033688943,0.00043166569,0.09155958,0.00047745576,0.00017183973,0.000020384303,0.0007949682,0.01347371,0.7740955,0.0020931917,0.112598866,0.0009139637],"about_ca_topic_score_codex":0.0000119030265,"about_ca_topic_score_gemma":0.0006404354,"teacher_disagreement_score":0.21427338,"about_ca_system_score_codex":0.000016953049,"about_ca_system_score_gemma":0.000033367443,"threshold_uncertainty_score":0.4505802},"labels":[],"label_agreement":null},{"id":"W4411913554","doi":"10.1101/2025.06.30.662330","title":"Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screens","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institute for Advanced Research; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Canada Foundation for Innovation","keywords":"CRISPR; Computational biology; Cas9; Biology; Genome; Genome editing; Genetics; Gene","score_opus":0.013819111797739295,"score_gpt":0.2908466418938314,"score_spread":0.2770275300960921,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411913554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9401142,0.0022548512,0.0555672,0.000027111437,0.00038268848,0.0003701187,0.0012236018,0.00003531151,0.000024924417],"genre_scores_gemma":[0.98728967,0.0004432811,0.011910298,0.00006990563,0.00011967319,0.00008375502,0.000013861857,0.000052120053,0.00001744201],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99757916,0.00012117916,0.0007533887,0.00097631285,0.00019478152,0.00037515795],"domain_scores_gemma":[0.9979066,0.0000688789,0.00031699636,0.0012691234,0.00030697027,0.00013142792],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002125081,0.0004571845,0.0007279437,0.00078610826,0.0000653171,0.00005303045,0.00052620686,0.00034238928,0.00005430231],"category_scores_gemma":[0.0001233371,0.0005582796,0.00036550887,0.0008276441,0.00009008505,0.0000054734182,0.00054240355,0.0004427778,0.00000474953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002866146,0.00011373025,0.030351881,0.00010481853,0.0014648015,0.00001075228,0.000019868477,0.02756586,0.940232,0.000027279088,0.000079427366,9.128711e-7],"study_design_scores_gemma":[0.000256379,0.00005013569,0.39899427,0.00012455383,0.00080478814,1.7232508e-9,0.000013695566,0.0020998358,0.5960637,0.0000011873138,0.0011372804,0.00045419417],"about_ca_topic_score_codex":0.00069300923,"about_ca_topic_score_gemma":0.00040850186,"teacher_disagreement_score":0.3686424,"about_ca_system_score_codex":0.00008930686,"about_ca_system_score_gemma":0.00022381096,"threshold_uncertainty_score":0.9996869},"labels":[],"label_agreement":null},{"id":"W4411947913","doi":"10.3389/fgene.2025.1611003","title":"Statistic tells: the regulatory pendulum of permit trajectories in China’s genetic governance (2021-2024)","year":2025,"lang":"en","type":"article","venue":"Frontiers in Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"China; Multinational corporation; Interim; Business; Human rights; Beijing; Corporate governance; Enforcement; License; Sovereignty; Genetic resources; Promulgation; Public administration; International trade; Political science; Law; Finance; Biotechnology; Biology; Politics","score_opus":0.0026549453550474464,"score_gpt":0.24237175859145527,"score_spread":0.2397168132364078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411947913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89571315,0.04329648,0.05677652,0.00012870561,0.0021390496,0.00039951497,0.000058114107,0.000005990702,0.0014824971],"genre_scores_gemma":[0.98056453,0.003927833,0.013265028,0.00004451731,0.00009539367,0.00002862151,0.000015741542,0.00002304236,0.0020353033],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987364,0.000066070366,0.00039871834,0.000339561,0.00015847522,0.00030076527],"domain_scores_gemma":[0.99930346,0.00001599831,0.000075806805,0.00053352444,0.000035885038,0.000035317924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017368444,0.00019192981,0.00023972419,0.00008737319,0.000034506033,0.000014099001,0.0003666548,0.0001425325,0.000020477344],"category_scores_gemma":[0.00009113402,0.00017954678,0.00006616689,0.00031139975,0.00015966874,0.0000021532135,0.00011545613,0.00016622862,7.68277e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020713679,0.00025969782,0.67680156,0.0004949356,0.00022018781,0.000030661547,0.0013010901,0.08824519,0.079677835,0.00054212665,0.05475578,0.09746381],"study_design_scores_gemma":[0.0007458403,0.00012233316,0.91834384,0.00009127678,0.00003672108,0.000004093025,0.00050392863,0.00403487,0.05491811,0.0007099441,0.020195832,0.00029318786],"about_ca_topic_score_codex":0.00006451998,"about_ca_topic_score_gemma":0.00029635447,"teacher_disagreement_score":0.24154231,"about_ca_system_score_codex":0.000047080684,"about_ca_system_score_gemma":0.00014858365,"threshold_uncertainty_score":0.7321705},"labels":[],"label_agreement":null},{"id":"W4412056932","doi":"10.1016/j.cell.2026.04.031","title":"Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects","year":2025,"lang":"en","type":"preprint","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; Novo Nordisk Fonden; Chan Zuckerberg Initiative; Alex's Lemonade Stand Foundation for Childhood Cancer; U.S. Department of Veterans Affairs","keywords":"PTEN; Phenotype; Biology; Computational biology; LMNA; Genetics; Subcellular localization; Genetic variants; Interactome; Genetic heterogeneity; Gene; Signal transduction; PI3K/AKT/mTOR pathway","score_opus":0.0077592525965326335,"score_gpt":0.2627125969144212,"score_spread":0.2549533443178886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412056932","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2647057,0.06397141,0.6591424,0.00046266685,0.004329255,0.0020758538,0.0004454893,0.00017383145,0.004693418],"genre_scores_gemma":[0.95000887,0.0010135352,0.04288433,0.00056658423,0.0008324072,0.00017573465,0.0014005194,0.00008657957,0.0030314573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983686,0.00007709049,0.0002776628,0.0007876378,0.0001546343,0.00033436835],"domain_scores_gemma":[0.99864036,0.00005260911,0.000091924994,0.0009258018,0.00010536157,0.000183918],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015374292,0.0003812612,0.00029983357,0.000083275736,0.00007503387,0.00004140462,0.0002890191,0.00030068614,0.000029712703],"category_scores_gemma":[0.00006859369,0.00040536164,0.0002620457,0.00006264485,0.00004257806,0.000001107503,0.0005803658,0.00029913263,0.000030371111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011764943,0.00014235209,0.00008584744,0.0017965954,0.00008277691,0.000072246774,0.00001984484,0.019956328,0.96561414,0.00003742336,0.0112362495,0.00083853037],"study_design_scores_gemma":[0.0017817521,0.00007510578,0.0030686404,0.0009753304,0.00030910972,0.0000031594677,0.000012294235,0.011365427,0.9290762,0.00035025665,0.051748678,0.0012340546],"about_ca_topic_score_codex":0.0000068922664,"about_ca_topic_score_gemma":0.0000012957127,"teacher_disagreement_score":0.68530315,"about_ca_system_score_codex":0.000031351858,"about_ca_system_score_gemma":0.0002532199,"threshold_uncertainty_score":0.99983984},"labels":[],"label_agreement":null},{"id":"W4412124950","doi":"10.1126/sciadv.adv7234","title":"High-throughput multiplexed gene and cell doping analysis through CRISPR-Cas12a system integrated with blood direct PCR","year":2025,"lang":"en","type":"article","venue":"Science Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry; Korea Institute of Science and Technology; Ministry of Agriculture, Food and Rural Affairs; National Research Foundation of Korea; Ministry of Oceans and Fisheries; Yonsei University; World Anti-Doping Agency; National Research Foundation","keywords":"CRISPR; Throughput; Gene; Computational biology; Polymerase chain reaction; Biology; Computer science; Genetics","score_opus":0.0041064200230830974,"score_gpt":0.27175387903518505,"score_spread":0.26764745901210196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412124950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89438504,0.008630406,0.09525561,0.000041515857,0.00021242785,0.00016632488,0.000016546232,0.000045123536,0.0012469772],"genre_scores_gemma":[0.97154677,0.0003610813,0.027703665,0.00005032244,0.0000386663,0.00001871932,0.000017642331,0.000007918533,0.00025523006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870414,0.000020527865,0.0001817377,0.0006151049,0.00016970672,0.0003087721],"domain_scores_gemma":[0.99939406,0.000017986436,0.000060842212,0.00034788586,0.00012051355,0.000058713427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018373584,0.00017730994,0.00022997879,0.00013017337,0.00022739629,0.0000740713,0.0002510945,0.000051214705,0.0000019939716],"category_scores_gemma":[0.000040681956,0.00013716907,0.000048867405,0.001270808,0.0003037544,0.000026102096,0.00010830398,0.00006347282,8.1047943e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025330954,0.000024368852,0.004646269,0.00007387641,0.00011096816,0.000004550326,0.000082607905,0.017497221,0.9763442,0.00007415822,0.000011591346,0.0011048124],"study_design_scores_gemma":[0.00042054118,0.00010578627,0.0018310603,0.00004580014,0.00021545532,0.000005511497,0.00060054584,0.0007330687,0.9940805,0.000009655124,0.0017585164,0.00019356051],"about_ca_topic_score_codex":0.00011999562,"about_ca_topic_score_gemma":0.00014832304,"teacher_disagreement_score":0.07716169,"about_ca_system_score_codex":0.000019096708,"about_ca_system_score_gemma":0.0000948928,"threshold_uncertainty_score":0.55935925},"labels":[],"label_agreement":null},{"id":"W4412196453","doi":"10.1016/j.copbio.2025.103334","title":"Synergizing gene editing and cellular agriculture for a sustainable and healthy food future","year":2025,"lang":"en","type":"review","venue":"Current Opinion in Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Ste. Anne's Hospital","funders":"","keywords":"Agriculture; Sustainable agriculture; Biotechnology; Business; Biology; Ecology","score_opus":0.016847195656952356,"score_gpt":0.34147351870571446,"score_spread":0.3246263230487621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412196453","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000075658696,0.9918155,0.0051399283,0.00019941243,0.0017588781,0.00092973385,0.000043228538,0.000030685118,0.0000069970965],"genre_scores_gemma":[0.000077169214,0.99709237,0.0005438156,0.000007702508,0.0013618288,0.000280528,0.0005678776,0.000025328274,0.000043363598],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99849826,0.00003514401,0.0003644775,0.0006317359,0.000049078346,0.0004212912],"domain_scores_gemma":[0.9994793,0.0000269374,0.00012945481,0.0002600985,0.00004821067,0.000055988206],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015529584,0.00034202376,0.00064055773,0.00026829678,0.00009378471,0.000026580015,0.00017797024,0.001103687,4.5004765e-7],"category_scores_gemma":[0.00010438904,0.00030289954,0.00011350277,0.00025590797,0.00005999342,0.0000028316042,0.00033245995,0.00039957353,1.6995226e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011721953,0.00004815982,0.0000073500814,0.087813236,0.000084597545,0.000001275858,0.000018628994,0.0000065282516,0.00053392886,0.0041793864,0.0040743533,0.90322083],"study_design_scores_gemma":[0.000318394,0.00023260085,0.0000010168881,0.002591462,0.000049612598,0.000026416837,0.00013464293,0.00000843328,0.00091433525,0.000060817074,0.9953853,0.00027695307],"about_ca_topic_score_codex":0.0000018008346,"about_ca_topic_score_gemma":0.000002715144,"teacher_disagreement_score":0.99131095,"about_ca_system_score_codex":0.000029477435,"about_ca_system_score_gemma":0.00010267391,"threshold_uncertainty_score":0.9999423},"labels":[],"label_agreement":null},{"id":"W4412273284","doi":"","title":"To Regulate or Not: Regulatory Challenges of Genome Editing Crops in the EU","year":2018,"lang":"en","type":"article","venue":"Research at the University of Copenhagen (University of Copenhagen)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for International Governance Innovation","funders":"","keywords":"Genome; Genome editing; Computational biology; Biology; Genetics; Gene","score_opus":0.03728902727654465,"score_gpt":0.3100716664515311,"score_spread":0.27278263917498646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412273284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95654064,0.003037365,0.0010009585,0.0014889077,0.0000482008,0.0006087388,0.000044088036,0.0000073520537,0.03722375],"genre_scores_gemma":[0.9362607,0.00042837657,0.0004831492,0.000031701682,0.00007047422,1.6362114e-7,0.000012531642,0.000013479382,0.06269944],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981859,0.00039738536,0.0001611005,0.00035883475,0.00050632266,0.00039045585],"domain_scores_gemma":[0.9984771,0.0001202976,0.000117073985,0.0007828116,0.00039139602,0.000111335816],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0017396174,0.00014144446,0.00026737805,0.00014727621,0.00040016422,0.000008434215,0.0013565657,0.0001321646,0.014688746],"category_scores_gemma":[0.00010759257,0.00012719638,0.00012236251,0.0004713882,0.00074424176,0.00002019344,0.00089634623,0.0001734053,0.0014334985],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026250032,0.00013932365,0.000010532131,0.00022575395,0.0001982275,0.00007733604,0.012633652,0.00074863754,0.6085446,0.0002792976,0.37051943,0.003998189],"study_design_scores_gemma":[0.0012432495,0.0012306113,0.05984509,0.00011529739,0.000050825813,0.000015447253,0.026876152,0.00014149748,0.14004758,0.0000047960193,0.7701727,0.0002567204],"about_ca_topic_score_codex":0.00034952819,"about_ca_topic_score_gemma":0.0029149111,"teacher_disagreement_score":0.46849704,"about_ca_system_score_codex":0.000058603542,"about_ca_system_score_gemma":0.00016258424,"threshold_uncertainty_score":0.999344},"labels":[],"label_agreement":null},{"id":"W4412374365","doi":"10.1111/pbi.70256","title":"Development of novel transgene‐free high‐oleic peanuts through <scp>CRISPR</scp>‐Cas9‐mediated gene editing of two <i>AhFAD2</i> homologues","year":2025,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Henan Provincial Science and Technology Research Project; National Key Research and Development Program of China","keywords":"Biology; CRISPR; Transgene; Gene; Genome editing; Cas9; Genetics; Computational biology; Biotechnology","score_opus":0.01045596938011358,"score_gpt":0.2657030051005313,"score_spread":0.25524703572041774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412374365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7884528,0.0042343056,0.20603624,0.00024217519,0.00052895694,0.00012254482,0.00018569258,0.00003563748,0.00016166068],"genre_scores_gemma":[0.9227433,0.0017947955,0.074870974,0.000097291064,0.00018364628,0.000009389416,0.00020756436,0.000025068432,0.00006797635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982203,0.000030008216,0.00075690664,0.00034029112,0.00019059832,0.00046188914],"domain_scores_gemma":[0.99904835,0.000056915822,0.00029795957,0.00040548938,0.00012798919,0.00006330845],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034092768,0.00027509476,0.00042030128,0.00025843302,0.00013268359,0.00001189641,0.00064313837,0.00052799634,0.0000041656613],"category_scores_gemma":[0.00025059876,0.0002630362,0.0001280671,0.00028441177,0.0002062836,0.0000067964893,0.00023034133,0.00043846923,0.0000013111146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020188056,0.00013423407,0.0004238303,0.0000698182,0.00029713914,0.000016730677,0.00019752105,0.00044722017,0.99528974,0.00028917013,0.001158935,0.0016554864],"study_design_scores_gemma":[0.0018113146,0.0001453752,0.00046312486,0.00011148966,0.00006521727,0.00038311977,0.00035667926,0.000107085834,0.98110247,0.00015289798,0.015187323,0.00011392346],"about_ca_topic_score_codex":0.000015811687,"about_ca_topic_score_gemma":0.000057924808,"teacher_disagreement_score":0.1342905,"about_ca_system_score_codex":0.000025195237,"about_ca_system_score_gemma":0.00021184846,"threshold_uncertainty_score":0.9999822},"labels":[],"label_agreement":null},{"id":"W4412402430","doi":"10.1101/2025.07.12.25331452","title":"RAPID: Evaluation of Cas12a Protospacer Nicking and Chimeric Reporters for PAM-free RNA and DNA diagnostics","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Sinai Health System; Université Laval; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Advanced Research Projects Agency; Ministry of Colleges and Universities; University of Toronto; Canadian Institutes of Health Research; Defense Advanced Research Projects Agency; Canada Research Chairs; U.S. Department of Defense","keywords":"DNA; Biology; RNA; Computational biology; Molecular biology; Genetics; Gene","score_opus":0.023481793731878142,"score_gpt":0.33737258151320015,"score_spread":0.313890787781322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412402430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97666824,0.011746118,0.009343343,0.00011191813,0.00032012732,0.0015159112,0.00006633386,0.0000087115495,0.00021927054],"genre_scores_gemma":[0.994803,0.0021773882,0.002231305,0.00002276936,0.00013506346,0.00043942087,0.0001019356,0.000019876197,0.00006921681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989715,0.000041128547,0.0002757016,0.0004135049,0.00015574305,0.0001424026],"domain_scores_gemma":[0.9990581,0.00004134122,0.00016160804,0.00051039475,0.00018115206,0.000047358088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006339948,0.000181141,0.0002280721,0.00005876654,0.000032980566,0.000018210138,0.000118422795,0.00020104765,0.00000296045],"category_scores_gemma":[0.0010185337,0.0001838345,0.000066607114,0.000037482532,0.0000513717,0.0000012843537,0.00038466955,0.00009934328,4.1175213e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000126064,0.00010293281,0.044484958,0.0033508413,0.0007697998,0.0000061911064,0.00073795696,0.0031230885,0.85419166,0.00004131747,0.0019093564,0.091155834],"study_design_scores_gemma":[0.0020443834,0.0003168911,0.067029275,0.00050989445,0.00088519644,0.000026574993,0.00012300165,0.010142508,0.9101157,0.0008473146,0.0073005417,0.0006587096],"about_ca_topic_score_codex":0.000015697551,"about_ca_topic_score_gemma":0.000018008324,"teacher_disagreement_score":0.09049713,"about_ca_system_score_codex":0.000009525446,"about_ca_system_score_gemma":0.000110814166,"threshold_uncertainty_score":0.74965537},"labels":[],"label_agreement":null},{"id":"W4412448701","doi":"10.1038/s41587-025-02744-3","title":"Platform solutions for commercial challenges to expanding patient access and making gene editing sustainable","year":2025,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Society for Cellular Therapy","funders":"","keywords":"Genome editing; Business; Gene; Computational biology; Computer science; Biology; Genetics; CRISPR","score_opus":0.013660983885755233,"score_gpt":0.34097467997356623,"score_spread":0.327313696087811,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412448701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7672154,0.032813538,0.1799999,0.015473246,0.0013145251,0.0013046622,0.000045619552,0.0001748316,0.0016582954],"genre_scores_gemma":[0.99569565,0.00042167574,0.0030709212,0.00042285904,0.0001873723,0.0000843774,0.000020169215,0.000013443093,0.00008352907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909055,0.000005271076,0.0001278742,0.00032465238,0.00004263293,0.00040900512],"domain_scores_gemma":[0.9996393,0.000018060908,0.000030614916,0.00021504446,0.000066950655,0.000030077874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119480144,0.00012551015,0.0001280273,0.00018910761,0.00021741168,0.000027084801,0.00019105358,0.00072032836,9.569749e-7],"category_scores_gemma":[0.00023966953,0.00013081796,0.000037670838,0.00013601348,0.000038613143,0.000004609991,0.00056534226,0.00022224463,2.1201991e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016175663,0.00006924785,0.00029426298,0.00036028004,0.0001592215,0.000008608209,0.00021089714,0.00048028742,0.6842044,0.08391361,0.007571295,0.22256611],"study_design_scores_gemma":[0.0004365157,0.00025075176,0.00070614397,0.00004019176,0.00002420498,0.000014466706,0.0008617733,0.00013948754,0.76455534,0.0012615736,0.23148938,0.0002202062],"about_ca_topic_score_codex":0.0000034436325,"about_ca_topic_score_gemma":0.000052112027,"teacher_disagreement_score":0.22848028,"about_ca_system_score_codex":0.000026176584,"about_ca_system_score_gemma":0.0000277638,"threshold_uncertainty_score":0.5555832},"labels":[],"label_agreement":null},{"id":"W4412509146","doi":"10.1007/s00344-025-11784-7","title":"Precise A·T-to-G·C Base Editing in Banana","year":2025,"lang":"en","type":"article","venue":"Journal of Plant Growth Regulation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Natural Science Foundation of China","keywords":"Plant physiology; Base (topology); Biology; Botany; Mathematics","score_opus":0.005015571444041749,"score_gpt":0.26464414282364446,"score_spread":0.2596285713796027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412509146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.940523,0.00034695983,0.05770936,0.000366171,0.00043792892,0.0000810683,0.000006244061,0.0000025274119,0.00052670925],"genre_scores_gemma":[0.99778885,0.000032524335,0.0016295988,0.000051306502,0.00028767026,0.0000012755102,0.000015058398,0.000004520797,0.00018920188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994734,0.000013611914,0.00024910047,0.000087145,0.00008417973,0.00009255236],"domain_scores_gemma":[0.9997326,0.000011108058,0.00007063522,0.000077003424,0.00006974792,0.000038883594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025645513,0.00005868935,0.000090299196,0.00017271124,0.000016350405,0.000011157473,0.00008245023,0.000054407526,0.000004934581],"category_scores_gemma":[0.00013708493,0.000055401077,0.000040541367,0.0001268038,0.0000051768307,0.0000040741365,0.000025214022,0.000058834954,5.394407e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018065724,0.000041688243,0.027255695,0.000046251527,0.000034332585,0.000014725432,0.00008168096,0.020020701,0.9361448,0.00028713857,0.011133429,0.0047588767],"study_design_scores_gemma":[0.001319703,0.00025872563,0.19830552,0.00035949252,0.00003198474,0.00008154865,0.00011296418,0.0061427257,0.77935445,0.000794174,0.013032411,0.0002063167],"about_ca_topic_score_codex":0.0000040380883,"about_ca_topic_score_gemma":0.000023652214,"teacher_disagreement_score":0.17104982,"about_ca_system_score_codex":0.000018372102,"about_ca_system_score_gemma":0.00002895797,"threshold_uncertainty_score":0.22591904},"labels":[],"label_agreement":null},{"id":"W4412556021","doi":"10.1016/j.jconrel.2025.114053","title":"Lung tissue-optimized gene editing in human cystic fibrosis models following topical application of lipid nanoparticles","year":2025,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"FPInnovations; University of British Columbia","funders":"Stiftung Charité; Mitacs; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; Boehringer Ingelheim","keywords":"Genome editing; Cystic fibrosis; Genetic enhancement; CRISPR; Gene delivery; Lung; Gene; Gene mutation; Computational biology; Mutation; Biology; Medicine; Genetics; Internal medicine","score_opus":0.0038098985041067524,"score_gpt":0.2830619458256083,"score_spread":0.27925204732150155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412556021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7662507,0.0026043362,0.23059136,0.00011679109,0.00013576768,0.00016976905,0.0000011869006,0.0000027276008,0.00012735055],"genre_scores_gemma":[0.9960448,0.000056280103,0.0035294483,0.00003221371,0.00023757396,0.000013619543,0.0000034973846,0.000008269285,0.000074277275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989874,0.00005628167,0.0005839888,0.000113819624,0.00011949114,0.00013904693],"domain_scores_gemma":[0.9994869,0.000046739213,0.00018636812,0.00013765905,0.000088237175,0.00005409137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003129753,0.00009641251,0.00036507656,0.00010497278,0.000033182343,0.000012051824,0.000120555036,0.00008773059,0.0000027931953],"category_scores_gemma":[0.00019586286,0.00008593394,0.0001892325,0.00009236685,0.000015748505,0.00000654562,0.00003227257,0.00009836685,1.355978e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051429163,0.000056463825,0.000346658,0.000029891708,0.00008995229,0.0000052393357,0.000024028765,0.09908598,0.8981873,0.000074042604,0.00006747198,0.0015186701],"study_design_scores_gemma":[0.015546865,0.00024657202,0.0005670053,0.00014658802,0.000200974,0.000010125953,0.00006785015,0.08994592,0.8924559,0.00031683364,0.0003567332,0.00013865855],"about_ca_topic_score_codex":0.0000072161433,"about_ca_topic_score_gemma":0.0000047536623,"teacher_disagreement_score":0.2297941,"about_ca_system_score_codex":0.000018850935,"about_ca_system_score_gemma":0.00004993886,"threshold_uncertainty_score":0.35042846},"labels":[],"label_agreement":null},{"id":"W4412583883","doi":"10.1101/2025.07.22.666069","title":"A novel, high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways <i>ex vivo</i> and <i>in vivo</i>","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Cancer Council Victoria; National Health and Medical Research Council; Genentech","keywords":"In vivo; Ex vivo; CRISPR; Computational biology; Resistance (ecology); Cancer; Biology; Genetics; Gene; Ecology","score_opus":0.012675058764039017,"score_gpt":0.23944141928172383,"score_spread":0.2267663605176848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412583883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94171953,0.0034135368,0.0526691,0.0001433918,0.00043035325,0.0007732238,0.00078304776,0.000055526627,0.000012276042],"genre_scores_gemma":[0.98402405,0.0017763254,0.013318752,0.00023618614,0.0002719285,0.00028714706,0.0000015620043,0.00005262568,0.00003144689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981314,0.000018706709,0.00036462522,0.000924433,0.00015314897,0.00040768523],"domain_scores_gemma":[0.9989086,0.00004509307,0.00017458045,0.0005299754,0.00022326506,0.000118478696],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030978557,0.00042484252,0.00040796993,0.00015008026,0.0001250439,0.00010374683,0.00020378955,0.0005050427,0.000002764735],"category_scores_gemma":[0.00014252092,0.0004943277,0.000070297334,0.00016549745,0.00006967196,0.00001477957,0.00040692106,0.00030475308,1.8204877e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009343664,0.00003231873,0.0011984764,0.0008778907,0.00007689137,0.0000025974616,0.000017247168,0.00016745913,0.99691457,0.00020088097,0.0004121296,0.0000061183],"study_design_scores_gemma":[0.00077200134,0.000026097698,0.017939202,0.0005666344,0.000049042723,3.061312e-8,0.000011655484,0.00024261302,0.97212845,0.00000898468,0.0077028694,0.0005524292],"about_ca_topic_score_codex":0.00017356311,"about_ca_topic_score_gemma":0.0002749662,"teacher_disagreement_score":0.042304486,"about_ca_system_score_codex":0.000090456415,"about_ca_system_score_gemma":0.0003084383,"threshold_uncertainty_score":0.99975085},"labels":[],"label_agreement":null},{"id":"W4412697393","doi":"10.1007/978-1-0716-4730-1_10","title":"Creation of DMD Muscle Cell Model Using CRISPR-Cas9 Genome Editing to Test the Efficacy of Antisense-Mediated Exon Skipping","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"","keywords":"CRISPR; Genome editing; Exon skipping; Exon; Cas9; Computational biology; Biology; Genetics; Gene; Alternative splicing","score_opus":0.016620390728349314,"score_gpt":0.4091283688312372,"score_spread":0.3925079781028879,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412697393","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4146411,0.0006840942,0.58409894,0.000039359573,0.000086163534,0.00017909682,0.000010740829,0.000004584457,0.00025592404],"genre_scores_gemma":[0.6603095,0.000045481833,0.33942875,0.000106155334,0.000037048405,0.000009829008,0.000026934247,0.000015398076,0.000020908223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859315,0.0002788103,0.00045372033,0.00034660878,0.00006109718,0.00026663978],"domain_scores_gemma":[0.99910927,0.00021121312,0.00012457147,0.0004139258,0.0001044657,0.000036584242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080637523,0.00016615778,0.00028540211,0.00018461814,0.000039373717,0.000005766886,0.00024241091,0.00020310708,0.0000029424275],"category_scores_gemma":[0.0012455947,0.00015106269,0.00010379246,0.00037116493,0.000082084895,0.0000016956027,0.00020524059,0.000121365556,3.1884238e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016143093,0.000059612747,0.00058496563,0.000047112375,0.00002073751,0.00000123084,0.000094737945,0.08785853,0.9088075,0.000048992704,0.000004213045,0.0024562406],"study_design_scores_gemma":[0.0004234276,0.0001279131,0.0014138178,0.00003760483,0.000033335044,0.0000020178018,0.00009255964,0.026989026,0.9702021,0.00014587383,0.00040232643,0.00013001132],"about_ca_topic_score_codex":0.000045856796,"about_ca_topic_score_gemma":0.000008414597,"teacher_disagreement_score":0.24566838,"about_ca_system_score_codex":0.000018740631,"about_ca_system_score_gemma":0.00006684022,"threshold_uncertainty_score":0.6160158},"labels":[],"label_agreement":null},{"id":"W4412702538","doi":"10.1101/2025.07.18.665591","title":"Genomic response to sex-separated gene pools","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Vetenskapsrådet; University of Toronto","keywords":"Gene; Genetics; Biology; Computational biology","score_opus":0.008045805745601329,"score_gpt":0.2596893917449613,"score_spread":0.25164358599936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412702538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98061216,0.0021761246,0.014473569,0.00019515138,0.0010232403,0.0007864626,0.0005513148,0.00015930674,0.000022657106],"genre_scores_gemma":[0.9903292,0.00025694934,0.0077178315,0.0005251393,0.00056039274,0.00023783503,0.0000028443815,0.00011217153,0.00025764908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99727446,0.00015757814,0.0004861892,0.0012512428,0.00021202516,0.00061852235],"domain_scores_gemma":[0.9974495,0.000027738706,0.00013167295,0.0017563862,0.00028999103,0.0003446812],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005992767,0.0006049051,0.00049037137,0.00027443602,0.00010964805,0.00012968789,0.0007213505,0.0007074645,0.000021219188],"category_scores_gemma":[0.00026858915,0.0007261289,0.00019587805,0.00033197482,0.00004708835,0.0000031071802,0.0010598281,0.00041277613,0.00007030866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027121042,0.000046522768,0.00091596815,0.0001003122,0.00019060652,0.000020772177,0.000006407167,0.0055851866,0.99104875,0.000010157065,0.0018012226,0.0000028963475],"study_design_scores_gemma":[0.00038950183,0.00010692596,0.03044852,0.000099531826,0.000069596565,3.1131115e-8,0.0000013461242,0.00020726022,0.91266954,3.270493e-7,0.055260684,0.00074676453],"about_ca_topic_score_codex":0.00002107715,"about_ca_topic_score_gemma":0.0000023070452,"teacher_disagreement_score":0.07837923,"about_ca_system_score_codex":0.00013605677,"about_ca_system_score_gemma":0.0007808636,"threshold_uncertainty_score":0.999519},"labels":[],"label_agreement":null},{"id":"W4412731360","doi":"10.21203/rs.3.rs-7160959/v1","title":"Proteus Project - CRISPR-Based Programmable Therapeutics for Targeted Apoptosis in Cancer Cells","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CRISPR; Apoptosis; Cancer research; Targeted therapy; Cancer; Puma; Proteus; Computational biology; Chemistry; Biology; Genetics; Gene","score_opus":0.06661838882193488,"score_gpt":0.4699540165440875,"score_spread":0.40333562772215265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412731360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6710367,0.0702327,0.16198687,0.0045427918,0.0034414232,0.07875985,0.006528695,0.0004266103,0.0030443647],"genre_scores_gemma":[0.9390009,0.0035045657,0.021595376,0.00018059602,0.00096364843,0.028756332,0.0017544575,0.00016771117,0.0040764003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974598,0.00018520404,0.00031190718,0.00078361767,0.00037064633,0.00088876893],"domain_scores_gemma":[0.99860346,0.00005957892,0.000057223107,0.00069357717,0.0005123482,0.0000738124],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00088546344,0.00030220347,0.00031034433,0.00028612194,0.00010998013,0.000097859185,0.00048428253,0.00056409487,0.000011784152],"category_scores_gemma":[0.00010439475,0.0002980551,0.00020414226,0.00038299692,0.000072935545,0.0000016885194,0.0004756167,0.0006915922,0.0000012897142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010248179,0.0007542154,0.002668013,0.013474496,0.00046132374,0.0000051485044,0.00031935904,0.11753847,0.8194269,0.000044657932,0.018274676,0.026007907],"study_design_scores_gemma":[0.000740165,0.00040030992,0.00015608835,0.0005525741,0.000025248804,1.2207957e-7,0.00008291874,0.0057360022,0.88159114,0.0001089909,0.11026593,0.00034048993],"about_ca_topic_score_codex":0.00077197485,"about_ca_topic_score_gemma":0.00047291443,"teacher_disagreement_score":0.2679642,"about_ca_system_score_codex":0.00012584815,"about_ca_system_score_gemma":0.0016199903,"threshold_uncertainty_score":0.99994713},"labels":[],"label_agreement":null},{"id":"W4412755841","doi":"10.1007/978-3-031-72230-1_60","title":"Mutation Specific Treatments for Inherited Retinal Diseases","year":2025,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto","funders":"","keywords":"Retinal; Mutation; Genetics; Medicine; Biology; Ophthalmology; Gene","score_opus":0.030387323079962697,"score_gpt":0.4624902530301113,"score_spread":0.43210292995014865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412755841","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021684225,0.99768895,0.0008463422,0.000012894948,0.00039128703,0.0005645599,0.000055482888,0.0000073540396,0.0002162993],"genre_scores_gemma":[0.00086531223,0.9962366,0.00044109696,0.000041135158,0.000337879,0.0003571168,0.0015937095,0.000015104392,0.00011202808],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99904245,0.00004218601,0.0002985387,0.00041164472,0.000027720007,0.0001774669],"domain_scores_gemma":[0.9996589,0.00006599965,0.00007578933,0.00014153346,0.000013690721,0.000044076143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004081706,0.00024998537,0.0005753676,0.00010766741,0.00003204368,0.0000031809493,0.000088785666,0.000169276,0.000008590433],"category_scores_gemma":[0.00004497077,0.00018629144,0.000082895196,0.000090034584,0.00013207505,0.0000028644706,0.000052679232,0.000054960965,4.4661166e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059296373,0.00006472224,0.000054553126,0.0016046882,0.000060678274,0.000004012364,0.000033688357,0.0000012715548,0.0021575934,0.000116929565,0.00022773365,0.9956148],"study_design_scores_gemma":[0.00077616255,0.0009345101,0.0000093803765,0.0017766327,0.000107458225,0.000019492356,0.00013635748,0.0000019903637,0.0008626542,0.00006030467,0.9951293,0.00018574306],"about_ca_topic_score_codex":0.0000032529529,"about_ca_topic_score_gemma":0.0000029971118,"teacher_disagreement_score":0.9954291,"about_ca_system_score_codex":0.000022745739,"about_ca_system_score_gemma":0.00002620722,"threshold_uncertainty_score":0.75967443},"labels":[],"label_agreement":null},{"id":"W4412755890","doi":"10.1007/978-3-031-72230-1_58","title":"The Genetic Basis of IRDS and the Role of Genetic Testing","year":2025,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto","funders":"","keywords":"Basis (linear algebra); Genetic testing; Computational biology; Genetics; Biology; Mathematics","score_opus":0.014374384263138145,"score_gpt":0.39515958470287993,"score_spread":0.3807852004397418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412755890","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015392342,0.99732983,0.00009066541,0.00001655377,0.00013392435,0.00030762027,0.000006190771,0.0000018349134,0.00057416974],"genre_scores_gemma":[0.031086259,0.9681671,0.0005147319,0.000020464888,0.00010588583,0.00007137191,0.000010244599,0.0000091610445,0.000014755598],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99897873,0.000110478424,0.0004678936,0.00024875978,0.000042243926,0.00015191469],"domain_scores_gemma":[0.99917614,0.0003871412,0.0001660833,0.00022384805,0.000022672692,0.000024118866],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016707196,0.0001928218,0.0006274113,0.000053269836,0.000043227574,0.000002097116,0.00018619395,0.00012733562,0.0000016985367],"category_scores_gemma":[0.00021394569,0.00009683277,0.000060118753,0.00012315645,0.00086358585,0.0000011986585,0.00018372826,0.00009028354,5.5182603e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022978813,0.000010523743,0.00038254977,0.0008272403,0.000039804,3.7682852e-7,0.000057067413,0.0000034453963,0.0048734373,0.00018456166,0.0000044802523,0.9935935],"study_design_scores_gemma":[0.0013921259,0.0010663099,0.00013064838,0.0033303506,0.00025127412,0.00007796435,0.0011741158,0.00005873075,0.012951398,0.0005828332,0.97870123,0.00028299782],"about_ca_topic_score_codex":0.000038076218,"about_ca_topic_score_gemma":0.000014647371,"teacher_disagreement_score":0.9933105,"about_ca_system_score_codex":0.000004772883,"about_ca_system_score_gemma":0.000032385018,"threshold_uncertainty_score":0.3948726},"labels":[],"label_agreement":null},{"id":"W4412775058","doi":"10.3389/fgeed.2025.1632120","title":"Editorial: Gene editing to achieve Zero Hunger","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Ministry of Science and Technology, Pakistan","keywords":"Zero (linguistics); Computer science; Biology; Computational biology; Genetics; Linguistics; Philosophy","score_opus":0.0029303586912080262,"score_gpt":0.25822065359788554,"score_spread":0.25529029490667754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412775058","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019608856,0.0028299645,0.07837327,0.00008396804,0.91655976,0.00045625417,0.00037350142,0.000054402874,0.0010727912],"genre_scores_gemma":[0.00039957828,0.00041720166,0.016812196,0.0000786538,0.97750455,0.00015026076,0.00225035,0.00014549575,0.002241741],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961501,0.000088304325,0.00077616115,0.0012420294,0.00074377144,0.0009996841],"domain_scores_gemma":[0.9983642,0.00008814633,0.00022593848,0.0007662273,0.0003169353,0.00023855885],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008705496,0.00066731294,0.00073747436,0.00046098104,0.00015614583,0.00012148333,0.00084331405,0.0017031675,0.000008986245],"category_scores_gemma":[0.0021728477,0.00081500364,0.00024268733,0.00039502673,0.0000528832,0.000008015899,0.00063136715,0.0011458123,0.00001158654],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006896592,0.00002558709,0.00007603807,0.0001652212,0.00012340181,0.00000940893,0.000117225965,0.0024762931,0.014993062,7.5394536e-7,0.97992027,0.0020237807],"study_design_scores_gemma":[0.00057191215,0.00017533367,0.000019191832,0.00019086304,0.00005949985,9.077801e-7,0.00015624941,0.000045052962,0.0041734134,0.000047701087,0.99387795,0.0006819163],"about_ca_topic_score_codex":0.000042825846,"about_ca_topic_score_gemma":0.000028291854,"teacher_disagreement_score":0.06156107,"about_ca_system_score_codex":0.00022621868,"about_ca_system_score_gemma":0.00038836207,"threshold_uncertainty_score":0.99959284},"labels":[],"label_agreement":null},{"id":"W4412812796","doi":"10.1101/2025.07.30.667643","title":"Split Cas12a protospacer engineering enables ultra-specific, PAM-free detection","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université Laval","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Engineering","score_opus":0.006587115196253427,"score_gpt":0.22324975306413747,"score_spread":0.21666263786788403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412812796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8530953,0.009742527,0.12968317,0.0001691437,0.0034374353,0.0026388094,0.0005583147,0.0005872939,0.000088031215],"genre_scores_gemma":[0.9903297,0.00096808304,0.0066226614,0.00005207094,0.0011304808,0.0007001669,0.0000020898256,0.00014204955,0.00005272496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99731547,0.000051343693,0.00048562113,0.0012024267,0.0002818797,0.00066324364],"domain_scores_gemma":[0.9972341,0.00002279044,0.00017017138,0.0020455697,0.0003011205,0.00022623061],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034030815,0.0006980398,0.00046622418,0.00024160047,0.00012360157,0.00016926712,0.00071348523,0.00085972925,0.000019877905],"category_scores_gemma":[0.00023779125,0.0008171392,0.00024825466,0.00030597625,0.000058844722,0.00000858601,0.00058204116,0.0006522912,0.000014264673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034854023,0.00005166319,0.00030227957,0.0005579761,0.00017336725,0.000017227929,0.000005213923,0.0033752206,0.9947601,0.00008517411,0.0006232068,0.000013723202],"study_design_scores_gemma":[0.0004610824,0.00006092777,0.005897939,0.0002504688,0.00006451687,8.726899e-8,0.0000023431055,0.0003395106,0.9234261,9.4368943e-7,0.06869346,0.0008026082],"about_ca_topic_score_codex":0.00003563864,"about_ca_topic_score_gemma":0.000007082337,"teacher_disagreement_score":0.1372344,"about_ca_system_score_codex":0.00013367117,"about_ca_system_score_gemma":0.00024412789,"threshold_uncertainty_score":0.999428},"labels":[],"label_agreement":null},{"id":"W4412818268","doi":"10.21769/bioprotoc.5422","title":"Assembly and Mutagenesis of Human Coronavirus OC43 Genomes in Yeast via Transformation-Associated Recombination","year":2025,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Coronavirus; Recombination; Mutagenesis; Transformation (genetics); Genetics; Biology; Genome; Yeast; Virology; Mutation; Gene; Computational biology; Coronavirus disease 2019 (COVID-19)","score_opus":0.012636732479658727,"score_gpt":0.3519078569624783,"score_spread":0.33927112448281954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412818268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8395976,0.000053634103,0.003507558,0.000065911685,0.000052796284,0.15451911,0.000020360729,0.000020651794,0.0021624125],"genre_scores_gemma":[0.877555,0.0000035797561,0.00009264437,0.000018238916,0.000012224473,0.12213058,0.000033982546,0.000007820466,0.00014591769],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999417,0.000027964692,0.00023662686,0.00014766456,0.000059270496,0.00011143801],"domain_scores_gemma":[0.9997638,0.0000047943895,0.000051178373,0.000115609066,0.00004244309,0.000022216538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013978091,0.00009315174,0.00011287911,0.00008230437,0.000035188186,0.000010185579,0.0000732631,0.00011085652,0.000010805707],"category_scores_gemma":[0.000014018931,0.00009774061,0.00003494824,0.00011737536,0.000023198725,0.0000038520798,0.000026324029,0.000035955316,7.7518126e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042313673,0.00007367241,0.009186116,0.00014472524,0.00002581133,4.5539124e-7,0.00007725568,0.000053428917,0.964143,0.00009550628,0.00005172573,0.026106002],"study_design_scores_gemma":[0.0021961408,0.00022482821,0.1439936,0.00005025976,0.0000107250935,9.719846e-7,0.00005663304,0.0003595929,0.8436324,0.00011490226,0.009206787,0.00015314865],"about_ca_topic_score_codex":0.000052657935,"about_ca_topic_score_gemma":0.0001507465,"teacher_disagreement_score":0.13480748,"about_ca_system_score_codex":0.000018880253,"about_ca_system_score_gemma":0.00002612633,"threshold_uncertainty_score":0.39857462},"labels":[],"label_agreement":null},{"id":"W4412840119","doi":"10.21203/rs.3.rs-7151933/v1","title":"Escherichia coli proteins uL29 and ACP stabilize the Tn7-encoded TnsD and its DNA binding","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Transposase; Biology; Transposable element; Genetics; Ribosomal protein; Escherichia coli; DNA; Binding site; DNA-binding protein; Gene; Computational biology; Mutant; Transcription factor; Ribosome; RNA","score_opus":0.03350345148560661,"score_gpt":0.39155128203193873,"score_spread":0.3580478305463321,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412840119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861087,0.009717146,0.0005530234,0.00067795784,0.00012853842,0.0016797087,0.0001709209,0.000022307588,0.00094167225],"genre_scores_gemma":[0.9928479,0.0039095846,0.00036591128,0.000025789097,0.00022040389,0.00038826978,0.00009471093,0.000030312178,0.0021170836],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979743,0.00025615148,0.0002185022,0.00068293145,0.00036521108,0.00050292263],"domain_scores_gemma":[0.99884963,0.00009797062,0.000043581847,0.0006086272,0.00024837576,0.00015182431],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010398942,0.00025800904,0.00023789635,0.00012039862,0.00027728648,0.00016533275,0.0003746687,0.0003894936,0.000019665471],"category_scores_gemma":[0.0005744161,0.0002056825,0.00007590808,0.00019022274,0.0001507267,0.0000028348502,0.0020309375,0.0008385288,0.000003238951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009606417,0.000056486126,0.0008823446,0.0023432719,0.00015345794,0.000008450945,0.00056108105,0.00024924683,0.992209,0.0002638966,0.0010571338,0.0021195307],"study_design_scores_gemma":[0.00095029967,0.00053046196,0.005502022,0.0010340031,0.000055610468,0.0000103923485,0.0016050731,0.0033683376,0.9488788,0.00040146985,0.036915876,0.0007476075],"about_ca_topic_score_codex":0.00005324281,"about_ca_topic_score_gemma":0.00010145127,"teacher_disagreement_score":0.04333019,"about_ca_system_score_codex":0.00003504227,"about_ca_system_score_gemma":0.00030675204,"threshold_uncertainty_score":0.8387489},"labels":[],"label_agreement":null},{"id":"W4412851588","doi":"10.1016/j.ajt.2025.07.310","title":"Donor-Derived Transmissions 2023: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)","year":2025,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Optech (Canada)","funders":"","keywords":"Medicine; Advisory committee; Transmission (telecommunications); Post-hoc analysis; Disease; Internal medicine; Telecommunications; Public administration; Engineering; Political science","score_opus":0.004387601830649485,"score_gpt":0.2784871786122059,"score_spread":0.2740995767815564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412851588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7895682,0.0023064874,0.20723724,0.000607669,0.00008429848,0.00007295396,0.0000440926,0.0000025598818,0.00007650234],"genre_scores_gemma":[0.99352366,0.004960212,0.0012488086,0.00011417472,0.000019384383,0.0000024969486,0.000038579507,0.000007798736,0.000084897314],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99914926,0.000092805785,0.0003652599,0.00012413008,0.0001543024,0.00011421233],"domain_scores_gemma":[0.99942666,0.000033633532,0.00017327839,0.00018259599,0.00008945845,0.0000943816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012540676,0.00011253848,0.00023935783,0.0001782747,0.000061752326,0.000007631422,0.00021919538,0.000035713987,0.000016268432],"category_scores_gemma":[0.000011492451,0.00008311573,0.00037580926,0.0005444374,0.00010283601,0.0000055743894,0.0000061613373,0.00010602008,1.4219066e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011243362,0.000121357436,0.0062363753,0.00011689819,0.001215423,0.0000069985317,0.0007160451,0.038918577,0.8742798,0.000013293961,0.00016811436,0.07708279],"study_design_scores_gemma":[0.0019099577,0.0006177313,0.6416921,0.00040947364,0.006390584,0.000018843479,0.0009404676,0.0021668016,0.33663994,0.00005266392,0.008832306,0.00032910838],"about_ca_topic_score_codex":0.000011066216,"about_ca_topic_score_gemma":0.000019619585,"teacher_disagreement_score":0.6354557,"about_ca_system_score_codex":0.000010048745,"about_ca_system_score_gemma":0.000120175624,"threshold_uncertainty_score":0.33893612},"labels":[],"label_agreement":null},{"id":"W4412918610","doi":"10.3390/plants14152290","title":"RNA-Seq Identification of Peanut Callus-Specific Promoters and Evaluation of Base-Editing Efficiency.","year":2025,"lang":"en","type":"article","venue":"PubMed","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Henan Provincial Science and Technology Research Project; National Key Research and Development Program of China","keywords":"Biology; Promoter; Callus; Gene; Guide RNA; RNA; Arachis hypogaea; Cauliflower mosaic virus; Genetics; Genome editing; CRISPR; Gene expression; Computational biology; Database; Genetically modified crops; Transgene; Botany","score_opus":0.015963051969612653,"score_gpt":0.28194093672530424,"score_spread":0.26597788475569156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412918610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98319125,0.0016920689,0.013774164,0.00006336334,0.00015514146,0.0003739153,0.000006597416,0.0000042597653,0.0007392532],"genre_scores_gemma":[0.9995383,0.000064952175,0.000110251145,0.0000059343693,0.0000381911,0.00011211142,0.000021733244,0.000004392307,0.000104133884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993641,0.00003087725,0.00021207774,0.00016057909,0.00013257089,0.00009981929],"domain_scores_gemma":[0.99961114,0.000008143844,0.000072053655,0.00016060493,0.00012655336,0.000021527918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007526425,0.0000552661,0.00007309524,0.000055632056,0.000018981927,0.0000069748467,0.00006427445,0.00004417575,0.0000017337155],"category_scores_gemma":[0.0001458054,0.000057235873,0.000027671562,0.00008813453,0.000039981827,0.000001978384,0.000033739438,0.000025407719,1.1456488e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013101183,0.00003571849,0.0013197667,0.00009407097,0.000025887775,9.639814e-8,0.000077832345,0.0017981066,0.8286612,0.00006496997,0.00016693611,0.16774233],"study_design_scores_gemma":[0.00033533043,0.000012822325,0.1333272,0.000010810141,0.00003312635,7.6615817e-7,0.000072739276,0.002946992,0.862835,0.000043047454,0.00032986604,0.000052317504],"about_ca_topic_score_codex":0.0000048463144,"about_ca_topic_score_gemma":0.0000037799553,"teacher_disagreement_score":0.16769001,"about_ca_system_score_codex":0.000010471279,"about_ca_system_score_gemma":0.000019624269,"threshold_uncertainty_score":0.2334011},"labels":[],"label_agreement":null},{"id":"W4412940614","doi":"10.1038/s41467-025-62408-3","title":"Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de recherche du Québec – Nature et technologies; Wallonie-Bruxelles International; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Streptococcus thermophilus; CRISPR; Context (archaeology); Biology; Computational biology; Genetics; Bacteria; Gene","score_opus":0.010005984730262941,"score_gpt":0.31620879640186594,"score_spread":0.306202811671603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412940614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5755414,0.3584378,0.029730638,0.002315302,0.00071935647,0.0012391555,0.0008331162,0.00009569155,0.031087566],"genre_scores_gemma":[0.99644125,0.0006092587,0.0018089642,0.00009422079,0.000021299373,0.000032049425,0.00044944638,0.00001068709,0.0005328538],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99936587,0.000063649866,0.00022281423,0.00015589042,0.000072223156,0.00011952742],"domain_scores_gemma":[0.9986566,0.000053564898,0.0000685375,0.0011170568,0.000079930884,0.000024350631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012875351,0.000099393306,0.0001128528,0.000043513443,0.00011842815,0.000013640006,0.0005627232,0.00011685141,0.0000046903438],"category_scores_gemma":[0.000044395612,0.00010481038,0.000051928342,0.00012979194,0.00005669539,0.0000022091374,0.00024280741,0.00023207691,4.6227356e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032438256,0.0001275141,0.005608968,0.00010781168,0.00026128607,4.6834657e-7,0.00020407379,0.000670776,0.93285656,0.007970034,0.05062622,0.0015338463],"study_design_scores_gemma":[0.0010452345,0.00004679356,0.0033277085,0.00022720084,0.00009340019,0.0000022304018,0.0010454284,0.0012527854,0.24362129,0.00015455789,0.74882615,0.0003572462],"about_ca_topic_score_codex":0.00002299293,"about_ca_topic_score_gemma":0.00013218726,"teacher_disagreement_score":0.6981999,"about_ca_system_score_codex":0.000014829583,"about_ca_system_score_gemma":0.00003192483,"threshold_uncertainty_score":0.4274043},"labels":[],"label_agreement":null},{"id":"W4412988177","doi":"10.1016/j.talanta.2025.128680","title":"A rapid and highly sensitive CRISPR assay utilizing Cas12a orthologs for the detection of Novel Duck Reovirus","year":2025,"lang":"en","type":"article","venue":"Talanta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China; Innovative Research Group Project of the National Natural Science Foundation of China","keywords":"Chemistry; CRISPR; Computational biology; Gene; Biochemistry","score_opus":0.012623167797632914,"score_gpt":0.292339052055619,"score_spread":0.2797158842579861,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412988177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87729186,0.0023512344,0.11919414,0.00013847361,0.00021079925,0.00024152658,0.00003776078,0.000010122993,0.00052405585],"genre_scores_gemma":[0.99892807,0.00036231187,0.00023980638,0.00008561205,0.00005730728,0.0000146575285,0.000012121665,0.0000078480425,0.00029229204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999567,0.000013240775,0.00010941702,0.00016373681,0.00003523317,0.00011141793],"domain_scores_gemma":[0.9996854,0.000058845482,0.00003126692,0.00016134887,0.000046552163,0.000016590422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001677419,0.0000796173,0.0000901112,0.000028568853,0.0000617154,0.000007898295,0.000049228587,0.000072997864,5.662371e-7],"category_scores_gemma":[0.00008830226,0.00006314877,0.000045271652,0.00005281951,0.00004591671,0.000001284742,0.000055157645,0.00004599709,2.0369701e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006869656,0.000012206885,0.00015084125,0.000032493997,0.000051596395,6.082909e-7,0.00006553171,0.000043122764,0.98835516,0.00006632317,0.0001247767,0.011028671],"study_design_scores_gemma":[0.00046538044,0.00009148127,0.004932782,0.000015230595,0.00005011501,0.000025579084,0.00029120612,0.0011653047,0.9824917,0.000008159153,0.0103882775,0.00007480855],"about_ca_topic_score_codex":0.000045160014,"about_ca_topic_score_gemma":0.000097968434,"teacher_disagreement_score":0.12163616,"about_ca_system_score_codex":0.0000042547554,"about_ca_system_score_gemma":0.000017143819,"threshold_uncertainty_score":0.25751323},"labels":[],"label_agreement":null},{"id":"W4413008913","doi":"10.1101/2025.08.04.665369","title":"A platform for the systematic interrogation of genetic interactions in human cells: 26 gene by genome-wide double knockout screens as a proof of concept","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; Université du Québec à Montréal; McGill University; Jewish General Hospital; Montreal Clinical Research Institute; Université de Montréal; Hospital for Sick Children; University of British Columbia; Institute for Research in Immunology and Cancer","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Interrogation; Genome; Human genome; Computational biology; Proof of concept; Gene; Biology; Genetics; Physics; Computer science; Political science","score_opus":0.013459606733913655,"score_gpt":0.27219671496740716,"score_spread":0.2587371082334935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413008913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8945762,0.0063825115,0.09522653,0.00003238165,0.00042426237,0.0028626753,0.0004528552,0.0000309185,0.000011692915],"genre_scores_gemma":[0.99709857,0.00009682487,0.0018670901,0.000029615,0.00009297901,0.0007092552,0.00000528384,0.00005620757,0.000044180437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981716,0.000043469943,0.0008478765,0.0005018531,0.00016162306,0.00027356675],"domain_scores_gemma":[0.99814457,0.000073589996,0.00048248126,0.00089592824,0.0003384158,0.00006499842],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003184521,0.00033233463,0.00053212163,0.00017369159,0.000064193286,0.000033917837,0.00049996615,0.0002485571,0.000008107376],"category_scores_gemma":[0.00008417045,0.000311103,0.00020635246,0.0001928144,0.00008914306,0.0000061498286,0.0003160775,0.00023961945,6.682635e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055710803,0.000100222394,0.00021390713,0.005286173,0.00027761274,8.063717e-7,0.00005552673,0.007591929,0.9862928,0.00003280649,0.000091168906,0.0000013759461],"study_design_scores_gemma":[0.0007324752,0.00012019815,0.0010522794,0.0014969787,0.00019491978,2.7853073e-8,0.00005142699,0.0012387034,0.9944109,0.0000012751826,0.00042861735,0.0002722387],"about_ca_topic_score_codex":0.00014180387,"about_ca_topic_score_gemma":0.000053704876,"teacher_disagreement_score":0.102522396,"about_ca_system_score_codex":0.00009515368,"about_ca_system_score_gemma":0.00031125458,"threshold_uncertainty_score":0.9999341},"labels":[],"label_agreement":null},{"id":"W4413051598","doi":"10.1016/j.omtn.2025.102636","title":"Off-target effects in CRISPR-Cas genome editing for human therapeutics: Progress and challenges","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"HORIZON EUROPE Framework Programme; Consejería de Salud y Consumo, Junta de Andalucía; Junta de Andalucía; Novo Nordisk Fonden; Danmarks Frie Forskningsfond; Novo Nordisk; Deutsche Forschungsgemeinschaft; European Cooperation in Science and Technology; HORIZON EUROPE European Institute of Innovation and Technology; European Commission; Fundación Mutua Madrileña","keywords":"CRISPR; Genome editing; Computational biology; Biology; Human genome; Genome; Computer science; Genetics; Gene","score_opus":0.011703093945564196,"score_gpt":0.3065583232516798,"score_spread":0.29485522930611563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413051598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7840586,0.18141697,0.032147873,0.0008359233,0.00019090906,0.00087195006,0.000007120103,0.000038760463,0.000431906],"genre_scores_gemma":[0.99114126,0.00491255,0.0028811197,0.0005648855,0.00014898887,0.00019759573,0.000039841038,0.000055374152,0.00005838996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880517,0.00005657087,0.00021778504,0.00046192523,0.00009420978,0.00036434183],"domain_scores_gemma":[0.99949026,0.000017985225,0.00004392777,0.00034530342,0.000050195624,0.00005229851],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021945941,0.00025175288,0.00023572994,0.000108101274,0.00009220908,0.00003919043,0.00020486106,0.00019772908,0.0000030556325],"category_scores_gemma":[0.000017001083,0.00025383916,0.00010134697,0.00008958321,0.00008021856,0.000004180637,0.00008476578,0.00010709456,7.16638e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007947668,0.00009314081,0.0014927002,0.00022312086,0.00020066659,0.00001041136,0.00031020635,0.00008636469,0.91469043,0.0011534861,0.00001724845,0.08164274],"study_design_scores_gemma":[0.00325856,0.0007989142,0.019332474,0.00009460526,0.000040207768,0.000008098254,0.00025112592,0.00039635063,0.8536994,0.0022401724,0.1193798,0.00050032855],"about_ca_topic_score_codex":0.0000036018885,"about_ca_topic_score_gemma":0.000008925785,"teacher_disagreement_score":0.20708267,"about_ca_system_score_codex":0.000017102002,"about_ca_system_score_gemma":0.00002156089,"threshold_uncertainty_score":0.99999136},"labels":[],"label_agreement":null},{"id":"W4413094648","doi":"10.1016/j.pharma.2025.08.001","title":"Computational genome engineering through AI-CRISPR-precision medicine integration in modern therapeutics","year":2025,"lang":"en","type":"review","venue":"Annales Pharmaceutiques Françaises","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"CRISPR; Precision medicine; Genome editing; Clinical trial; Computer science; Personalized medicine; Drug discovery; Pharmaceutical industry; Data science; Computational biology; Artificial intelligence; Biotechnology; Medicine; Bioinformatics; Biology; Gene","score_opus":0.05191800638319747,"score_gpt":0.4375679497937097,"score_spread":0.38564994341051223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413094648","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000642244,0.8545457,0.14411733,0.00008007452,0.00025764434,0.0004990042,0.00005369043,0.000045451416,0.00033686825],"genre_scores_gemma":[0.004779589,0.9914892,0.001353913,0.00045946613,0.00039780277,0.00010942393,0.001179196,0.00006804454,0.00016340787],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99810106,0.000096969656,0.0006915773,0.0005647265,0.00021690274,0.00032879002],"domain_scores_gemma":[0.9992444,0.00012200178,0.00012411142,0.00032209585,0.00012152308,0.00006585309],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022901369,0.00054711057,0.000856906,0.00027387257,0.00006052742,0.000030892505,0.00037610027,0.00038612037,0.000023412651],"category_scores_gemma":[0.000065880595,0.0004808244,0.000272639,0.00031466113,0.00007318292,0.000013279134,0.00013957133,0.0004675239,0.0000060205907],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000275309,0.00006537714,0.000009514941,0.004870766,0.00021884985,0.000011352924,0.00037988063,0.015246281,0.0016828708,0.00007207156,0.00065030647,0.9767652],"study_design_scores_gemma":[0.00035517244,0.00008202876,0.000014835748,0.0051939907,0.00025280225,0.000020630296,0.000020211497,0.0037486926,0.0011829248,0.000110051806,0.98854446,0.00047416694],"about_ca_topic_score_codex":0.000016977261,"about_ca_topic_score_gemma":0.000016001528,"teacher_disagreement_score":0.9878942,"about_ca_system_score_codex":0.000040935025,"about_ca_system_score_gemma":0.00016074334,"threshold_uncertainty_score":0.9997643},"labels":[],"label_agreement":null},{"id":"W4413113454","doi":"10.1093/nar/gkaf746","title":"Unlocking genetic potential: harnessing phage for targeted mutagenesis in phage-assisted evolution.","year":2025,"lang":"en","type":"article","venue":"PubMed","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Cancer Research Society","keywords":"Biology; Mutagenesis; Genetics; Computational biology; Bacteriophage; Phage display; DNA Transposable Elements; Mutation; Genome; Gene; Transposable element; Escherichia coli","score_opus":0.0074949438208770066,"score_gpt":0.2602399774859234,"score_spread":0.2527450336650464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413113454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6781925,0.0077135204,0.3121324,0.00012776424,0.000598039,0.00085024926,0.000017564304,0.00004204541,0.00032594538],"genre_scores_gemma":[0.9948556,0.00005414076,0.0025657655,0.000102197526,0.0001456548,0.0010873566,0.00005884202,0.000029193889,0.0011012917],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99872506,0.00003666999,0.00028356997,0.00040480078,0.00008620837,0.0004637078],"domain_scores_gemma":[0.9995341,0.000015002977,0.00004999683,0.0002732142,0.000060052786,0.00006765374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020698803,0.0001745516,0.0001729812,0.00016672029,0.00009306275,0.00004312767,0.00017943067,0.00014744439,0.0000040772716],"category_scores_gemma":[0.00013038641,0.0001954091,0.000116151146,0.00027518795,0.00003238739,0.000004303627,0.00008168887,0.00006479898,8.837425e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013680525,0.00014816508,0.007671286,0.00022763923,0.00016939068,0.000016668877,0.000032210493,0.017697627,0.7004289,0.00006187997,0.0013357569,0.2720737],"study_design_scores_gemma":[0.0017632594,0.000022313045,0.6716994,0.000025169626,0.00007638273,0.000010019732,0.00006286325,0.0033565215,0.3154792,0.0001378038,0.0070334906,0.00033359713],"about_ca_topic_score_codex":0.000025817371,"about_ca_topic_score_gemma":0.000040624236,"teacher_disagreement_score":0.6640281,"about_ca_system_score_codex":0.000057871963,"about_ca_system_score_gemma":0.00005349446,"threshold_uncertainty_score":0.7968552},"labels":[],"label_agreement":null},{"id":"W4413113830","doi":"10.1111/mec.70079","title":"Coexistence in Sympatry With Gene Flow Before Speciation Has Completed","year":2025,"lang":"en","type":"article","venue":"Molecular Ecology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of Guelph; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Sympatry; Biology; Genetic algorithm; Gene flow; Evolutionary biology; Genetics; Gene; Computational biology; Sympatric speciation; Genetic variation","score_opus":0.005502504347966612,"score_gpt":0.25469979034911305,"score_spread":0.24919728600114643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413113830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9328741,0.0003827045,0.06484503,0.00046370333,0.0001602531,0.00021536283,0.000007347412,0.000015037264,0.0010364669],"genre_scores_gemma":[0.99519515,0.000015481572,0.0038274375,0.00051631354,0.000040279956,0.000035961675,0.00014076929,0.000014770654,0.00021385841],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916536,0.000039793198,0.00017118765,0.0003113786,0.000062280014,0.00024998627],"domain_scores_gemma":[0.99959856,0.000006825432,0.000032084048,0.00027652865,0.00004965232,0.000036321748],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008131162,0.00013468535,0.00015816429,0.000094075,0.000043554846,0.000015152776,0.00014243694,0.00015022684,0.000015348287],"category_scores_gemma":[0.000037042937,0.00013624068,0.00004132197,0.00017849987,0.00006683205,0.000001551918,0.00007618374,0.00009148774,0.000005905172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014161138,0.00014273544,0.08818284,0.00006330837,0.0001448891,0.00014311579,0.0001304832,0.039051,0.8671198,0.0005287133,0.0007800917,0.0035714053],"study_design_scores_gemma":[0.002951353,0.0009591107,0.44153112,0.000051977426,0.00006240587,0.000076903096,0.00010872712,0.012115249,0.52478933,0.00040272102,0.016429096,0.00052198564],"about_ca_topic_score_codex":0.000015052619,"about_ca_topic_score_gemma":0.0009459833,"teacher_disagreement_score":0.35334828,"about_ca_system_score_codex":0.000033359527,"about_ca_system_score_gemma":0.00008508474,"threshold_uncertainty_score":0.55557334},"labels":[],"label_agreement":null},{"id":"W4413117376","doi":"10.1126/sciadv.adu2906","title":"Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs","year":2025,"lang":"en","type":"article","venue":"Science Advances","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"CRISPR; Pentose phosphate pathway; Carcinogenesis; Biology; Vulnerability (computing); Somatic cell; Cancer research; Genetics; Computer science; Gene; Biochemistry; Glycolysis; Computer security; Enzyme","score_opus":0.0050774099507278955,"score_gpt":0.3293650329372392,"score_spread":0.32428762298651126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413117376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98347366,0.0039276197,0.01217475,0.000054766322,0.00012865447,0.00012378891,0.000004512589,0.000008690867,0.00010358665],"genre_scores_gemma":[0.99804443,0.00022073218,0.0014816193,0.000031118958,0.00001539758,0.00002336546,0.0000062246936,0.0000029503922,0.00017417817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990246,0.00002388916,0.00018477777,0.00042636116,0.00011881493,0.00022153383],"domain_scores_gemma":[0.99960905,0.000014994892,0.00003678908,0.00024371229,0.000043313492,0.000052120267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004372352,0.000100286416,0.00013883591,0.00018373638,0.00011067459,0.00003678814,0.00016449715,0.00003062887,0.0000042846873],"category_scores_gemma":[0.00015638222,0.00009161567,0.000043679647,0.00090182293,0.00020094389,0.000021095922,0.0000871541,0.00004141814,9.018612e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015721585,0.000033585336,0.10691247,0.000044913362,0.000014610458,0.0000011611935,0.00009497188,0.006053159,0.8544116,0.00001885983,0.0000016458621,0.032397304],"study_design_scores_gemma":[0.00022477457,0.000034435867,0.30027208,0.000018789262,0.000029644802,0.0000010875553,0.00019437239,0.0028098894,0.6957949,0.00019028969,0.00030266633,0.00012707424],"about_ca_topic_score_codex":0.00004234311,"about_ca_topic_score_gemma":0.00030993097,"teacher_disagreement_score":0.1933596,"about_ca_system_score_codex":0.000026150394,"about_ca_system_score_gemma":0.00006538528,"threshold_uncertainty_score":0.37359786},"labels":[],"label_agreement":null},{"id":"W4413148317","doi":"10.1101/2025.08.11.669692","title":"Compound Delivery of eVLPs Enhances Prime Editing for Targeted Genome Engineering and High-Throughput Screening","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Throughput; Prime (order theory); High-throughput screening; Computer science; Computational biology; Genome; Biology; Genetics; Mathematics; Gene; Operating system","score_opus":0.0069535478639793325,"score_gpt":0.23158986190203776,"score_spread":0.22463631403805842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413148317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8136898,0.0077007045,0.17672747,0.000027842492,0.0007193272,0.00057113986,0.00048685746,0.00007458593,0.0000022229303],"genre_scores_gemma":[0.9411278,0.00054820057,0.057309017,0.000033686174,0.0007719699,0.00012266927,0.0000075589396,0.000072227485,0.0000068704235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980354,0.00002979415,0.00050728087,0.0008142956,0.00016758672,0.0004456761],"domain_scores_gemma":[0.99859846,0.000045946083,0.0002530271,0.0006306204,0.00034383402,0.00012811134],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033729672,0.00046450848,0.00053133734,0.00017165998,0.00009633077,0.00006681282,0.00034268718,0.00046008689,0.0000033889592],"category_scores_gemma":[0.00017255642,0.0005613166,0.00015022635,0.00015368914,0.00007132212,0.000009276801,0.0005721903,0.00027975417,4.6954779e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030512214,0.000026372016,0.00029522023,0.0008722922,0.0002713674,0.0000025347401,0.000006963157,0.0051437723,0.9932462,0.000054259737,0.000041921783,0.000008558436],"study_design_scores_gemma":[0.0005005639,0.00008438819,0.008744124,0.00037179596,0.00012279385,2.8952872e-8,0.000004738751,0.0028535686,0.98269933,7.0027835e-7,0.004088539,0.00052944885],"about_ca_topic_score_codex":0.00003660933,"about_ca_topic_score_gemma":0.000002224901,"teacher_disagreement_score":0.12743795,"about_ca_system_score_codex":0.000037156613,"about_ca_system_score_gemma":0.00019132883,"threshold_uncertainty_score":0.99968386},"labels":[],"label_agreement":null},{"id":"W4413327930","doi":"10.1016/j.lwt.2025.118361","title":"Sensitive and visual detection for Atlantic salmon in processed foods using PCR-CRISPR/Cas12a system","year":2025,"lang":"en","type":"article","venue":"LWT","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Tianjin Science and Technology Program; Tianjin Normal University; McGill University","keywords":"CRISPR; Fishery; Computational biology; Biology; Computer science; Genetics; Gene","score_opus":0.006664097715005281,"score_gpt":0.3085424933126722,"score_spread":0.30187839559766694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413327930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8100205,0.00027338997,0.18929398,0.000012936577,0.000106119536,0.00019339386,0.0000018353577,0.000010580307,0.000087241184],"genre_scores_gemma":[0.9992596,0.00001534784,0.00055369653,0.000021705351,0.000076378594,0.000017176195,0.000011011003,0.000009829218,0.000035263976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952316,0.000013155679,0.000107581836,0.00019384526,0.000030741245,0.0001315158],"domain_scores_gemma":[0.9998519,0.000011112984,0.000019911035,0.00006122778,0.000035252287,0.000020638014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000049551447,0.000083784296,0.00009783303,0.00005468801,0.000039184382,0.000017709182,0.00002370719,0.00008778723,1.251624e-7],"category_scores_gemma":[0.000029444946,0.000087782304,0.000025230238,0.00008440633,0.00001212447,0.0000021559686,0.000027489663,0.0000358646,1.7958266e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006416148,0.000010023339,0.0008458825,0.0003249337,0.000018579272,0.0000018975311,0.000034649664,0.00036649773,0.9963208,0.000022274411,0.0000066444377,0.0019836952],"study_design_scores_gemma":[0.00046514627,0.0000999781,0.0026694196,0.000088158624,0.000022308868,0.00001680842,0.00040019167,0.030501029,0.9652817,0.0000064525266,0.00034752864,0.000101275975],"about_ca_topic_score_codex":0.00004771287,"about_ca_topic_score_gemma":0.000120951634,"teacher_disagreement_score":0.18923907,"about_ca_system_score_codex":0.000018245815,"about_ca_system_score_gemma":0.000009726278,"threshold_uncertainty_score":0.35796583},"labels":[],"label_agreement":null},{"id":"W4413337922","doi":"10.1038/s41564-025-02089-2","title":"Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions","year":2025,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; Wellcome Trust; Wellcome","keywords":"Helicase; Biology; Human immunodeficiency virus (HIV); Loop (graph theory); Genetics; Virology; Computational biology; Gene; RNA; Combinatorics; Mathematics","score_opus":0.0032336525411813077,"score_gpt":0.277015732215058,"score_spread":0.2737820796738767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413337922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92516303,0.01413973,0.057719927,0.001274008,0.00067736185,0.00025792848,0.000060729053,0.0000460665,0.0006612241],"genre_scores_gemma":[0.9915902,0.00022190622,0.0026330058,0.000935315,0.00011778928,0.000023894847,0.0009938098,0.000013841095,0.0034702537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990707,0.00005398664,0.0002024658,0.00041126888,0.000019592808,0.00024200686],"domain_scores_gemma":[0.9994552,0.000026711963,0.0000365325,0.00035896196,0.0000811778,0.000041373783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010279152,0.00018950677,0.00017764427,0.00010748549,0.00007663197,0.000014026816,0.00021257799,0.0006442975,0.000016271708],"category_scores_gemma":[0.00013707922,0.00017499311,0.0001015223,0.0001398972,0.000085848296,0.0000018510656,0.0001192115,0.00034288588,0.000034479322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045459063,0.000024316567,0.00014424055,0.000016755715,0.00005590018,0.0000023666055,0.0000710026,0.00006500442,0.98389417,0.0005695178,0.013249528,0.0018617357],"study_design_scores_gemma":[0.0005819182,0.0001176286,0.00056133216,0.000014573767,0.000032851876,0.000056644192,0.00014949954,0.00006730333,0.78163517,0.0005310931,0.216,0.0002519964],"about_ca_topic_score_codex":0.000020216645,"about_ca_topic_score_gemma":0.00011714491,"teacher_disagreement_score":0.20275047,"about_ca_system_score_codex":0.0000318442,"about_ca_system_score_gemma":0.000062417865,"threshold_uncertainty_score":0.7136012},"labels":[],"label_agreement":null},{"id":"W4413340965","doi":"10.1101/2025.08.14.670372","title":"Temporal control of sgRNA library activation unlocks large-scale <i>in vivo</i> CRISPR screens","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"CRISPR; Subgenomic mRNA; Scale (ratio); Computer science; Biology; Computational biology; Geography; Genetics; Cartography","score_opus":0.004976866334111699,"score_gpt":0.23039542795419168,"score_spread":0.22541856162007998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413340965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8585396,0.0026088282,0.13489881,0.00025126885,0.0007682286,0.0010680035,0.0015649085,0.00014593959,0.00015443449],"genre_scores_gemma":[0.99502075,0.00031522923,0.0038348562,0.00027661506,0.00032944267,0.000095649324,0.0000045302877,0.00007497079,0.000047953516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978792,0.00009083594,0.000576556,0.00078675826,0.00021043331,0.00045623144],"domain_scores_gemma":[0.9984174,0.000023809465,0.0002547972,0.0010079418,0.00015990053,0.00013618958],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002834068,0.00044427917,0.0005210489,0.00024529928,0.00005117006,0.000046862693,0.00046414518,0.00057878526,0.000028085962],"category_scores_gemma":[0.0000835991,0.00051592564,0.00019902985,0.00031290812,0.000058281017,0.000013543714,0.0004504718,0.0004352119,0.0000018784832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009991902,0.00015757924,0.03401134,0.00038967928,0.0001164237,0.000005645315,0.000006157102,0.0023544652,0.9614013,0.00006905579,0.0013865114,0.0000019323513],"study_design_scores_gemma":[0.0010428048,0.00006699397,0.018287512,0.00036351182,0.000054642293,9.916143e-9,0.000006366057,0.0014139251,0.960907,0.000001334558,0.017369866,0.0004860777],"about_ca_topic_score_codex":0.000052960204,"about_ca_topic_score_gemma":0.000010478631,"teacher_disagreement_score":0.13648118,"about_ca_system_score_codex":0.000036299953,"about_ca_system_score_gemma":0.0004463762,"threshold_uncertainty_score":0.9997292},"labels":[],"label_agreement":null},{"id":"W4413376873","doi":"10.1101/2025.08.13.670096","title":"PAM adenine methylation and flanking sequence regulate SaCas9 activity in bacteria","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Methylation; Sequence (biology); Genetics; Biology; Gene","score_opus":0.011705146417153344,"score_gpt":0.2673943966714492,"score_spread":0.25568925025429584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413376873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99055165,0.0015521827,0.0068477723,0.000083304614,0.00044350902,0.00035348372,0.00010281387,0.000056266308,0.000009007408],"genre_scores_gemma":[0.9944723,0.00070438534,0.0044307173,0.000037967202,0.0002285425,0.00006768634,0.0000017688171,0.00004128142,0.000015299063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983255,0.00009170941,0.00029411842,0.0008157118,0.00013354442,0.0003394108],"domain_scores_gemma":[0.9989167,0.000019218352,0.00014422217,0.000704879,0.00011306151,0.000101906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036913765,0.00037149846,0.00034460198,0.00017428986,0.000057100027,0.00008337901,0.00023157566,0.00053712574,0.0000066577963],"category_scores_gemma":[0.00012286894,0.00043775342,0.000070819515,0.00020407,0.000055157296,0.000008989344,0.00050294277,0.00038808855,0.0000016023223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032482392,0.000025303083,0.0038211546,0.00025318383,0.000053423388,0.000009820757,0.000005749716,0.0006603804,0.995063,0.000025982594,0.000021495402,0.000027987337],"study_design_scores_gemma":[0.00030947686,0.000035100154,0.13086101,0.00025472435,0.000037025133,3.0872304e-8,8.356925e-7,0.001168352,0.86551505,0.0000018837804,0.0013920277,0.0004244598],"about_ca_topic_score_codex":0.000056617755,"about_ca_topic_score_gemma":0.000016690501,"teacher_disagreement_score":0.12954797,"about_ca_system_score_codex":0.000072954346,"about_ca_system_score_gemma":0.00020650683,"threshold_uncertainty_score":0.9998074},"labels":[],"label_agreement":null},{"id":"W4413412762","doi":"10.1139/gen-2025-0008","title":"The current regulatory status of biotechnologically bred crops in Canada and beyond","year":2025,"lang":"en","type":"review","venue":"Genome","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Université Laval; Lethbridge College","funders":"","keywords":"Biotechnology; Biology; Context (archaeology); Food security; Genetically modified organism; Genetically modified crops; Agriculture; Apprehension; Pace; Trait; Toolbox; Crop; Natural resource economics; Transgene; Agronomy; Gene; Ecology; Computer science; Genetics; Economics","score_opus":0.007300552992651201,"score_gpt":0.2800289826617627,"score_spread":0.2727284296691115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413412762","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011249931,0.998237,0.000052675307,0.0000088678335,0.00014600389,0.00022771615,0.00009198664,0.0000027852564,0.00010796044],"genre_scores_gemma":[0.0013074955,0.99840945,0.000054232107,0.000006651174,0.00002682885,0.000022782555,0.00006584143,0.000009947,0.00009674175],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99911916,0.000026546524,0.00029691443,0.00023578314,0.00007047174,0.00025111914],"domain_scores_gemma":[0.99948406,0.000023427192,0.00007925598,0.0003485818,0.000020082296,0.0000446147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008112063,0.00016454868,0.00037259358,0.000046263525,0.000026974429,0.000007019826,0.00019964133,0.00013151407,0.0000014866068],"category_scores_gemma":[0.00004972279,0.00011680979,0.00006683676,0.00011800229,0.00005147048,3.093559e-7,0.00020032104,0.00017039175,2.0246861e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000019667739,0.0000042866827,0.000018973538,0.0020746195,0.000030846844,0.0000014825334,0.00000287652,0.000011522877,0.0003753432,0.000021665128,0.00006475997,0.99739164],"study_design_scores_gemma":[0.000060632592,0.00002064883,0.00066509796,0.00035194014,0.00003478259,0.0000025760523,0.00000837791,6.650599e-7,0.00009708305,0.000012706599,0.99862087,0.00012463289],"about_ca_topic_score_codex":0.015607131,"about_ca_topic_score_gemma":0.22136556,"teacher_disagreement_score":0.9985561,"about_ca_system_score_codex":0.000072117495,"about_ca_system_score_gemma":0.0012380097,"threshold_uncertainty_score":0.990948},"labels":[],"label_agreement":null},{"id":"W4413438201","doi":"10.1016/b978-0-443-33351-4.00003-9","title":"The evolution and integration of omics technologies in clinical bioinformatics and precision medicine","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Durham College","funders":"","keywords":"Omics; Precision medicine; Computational biology; Bioinformatics; Biology; Data science; Computer science; Genetics","score_opus":0.010337495760350496,"score_gpt":0.30261957475679474,"score_spread":0.29228207899644426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413438201","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011626616,0.06395226,0.0087427655,0.00042337526,0.00070372,0.001345056,0.00003626138,0.00004430137,0.91312563],"genre_scores_gemma":[0.257394,0.07436444,0.0067532053,0.0000810853,0.00029080937,0.000043318727,0.00012479824,0.000058980233,0.6608894],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992811,0.00000958864,0.0004330575,0.00014093277,0.00006348924,0.00007182478],"domain_scores_gemma":[0.9995351,0.00006046376,0.00011460543,0.00023057414,0.000045071873,0.000014190532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035906414,0.00012409184,0.00019436986,0.00007130595,0.000028900644,0.000006488063,0.00008916717,0.0002656175,3.0120597e-7],"category_scores_gemma":[0.00020062007,0.00008430791,0.000029945808,0.000009031446,0.0002523591,0.0000010549495,0.00014361375,0.00016978405,1.4565076e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023950603,0.0000015056855,0.00004606927,0.000048168433,0.000016943159,1.6419752e-7,0.000026712942,0.0000013582912,0.0014952967,0.0017480276,0.000050431197,0.9965414],"study_design_scores_gemma":[0.0020844457,0.002098094,0.0020398255,0.0030005174,0.00024023125,0.000030849897,0.0010160658,0.0031923677,0.01020525,0.0337135,0.94163686,0.0007420149],"about_ca_topic_score_codex":6.4649294e-7,"about_ca_topic_score_gemma":0.00006206859,"teacher_disagreement_score":0.99579936,"about_ca_system_score_codex":0.000010882058,"about_ca_system_score_gemma":0.00003398046,"threshold_uncertainty_score":0.34379768},"labels":[],"label_agreement":null},{"id":"W4413473455","doi":"10.1038/s41467-025-63164-0","title":"Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Tornado Spectral Systems (Canada)","funders":"Common Fund; National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; Irving Medical Center, Columbia University; U.S. Department of Health and Human Services; National Institutes of Health; National Human Genome Research Institute; St. Jude Children's Research Hospital","keywords":"Gene; Computational biology; Biology; Genetics","score_opus":0.010305493899901763,"score_gpt":0.3370663779249291,"score_spread":0.32676088402502734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413473455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875083,0.0069068214,0.0047386116,0.00014790641,0.00021031284,0.00027252774,0.000039703704,0.000012158483,0.00016364657],"genre_scores_gemma":[0.9874293,0.00014211817,0.011967254,0.000045711964,0.000020519868,0.000014655519,0.00030775354,0.000009144441,0.00006351176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996067,0.000013519867,0.00015865812,0.00010284676,0.00003105542,0.000087179695],"domain_scores_gemma":[0.9992387,0.000018560891,0.000028575374,0.0005990156,0.000100318524,0.0000148013905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000061444305,0.00006998639,0.00008489715,0.00008387044,0.000035988938,0.000004478271,0.00029345913,0.00018750486,0.0000017104766],"category_scores_gemma":[0.000082788,0.0000777292,0.000033990596,0.00017881281,0.000016260152,0.0000015507261,0.00010078576,0.00015483893,1.0717393e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006089615,0.000018549263,0.00043408768,0.00002264675,0.000018380499,3.8568423e-8,0.000019482055,0.0045748325,0.9935405,0.00063771923,0.0005947378,0.00013293196],"study_design_scores_gemma":[0.00027009053,0.000026968624,0.008047771,0.00001698599,0.00001106033,6.319135e-7,0.000009046502,0.0020771567,0.9784802,0.00005110426,0.010935722,0.00007322216],"about_ca_topic_score_codex":0.0000113576225,"about_ca_topic_score_gemma":0.00019715661,"teacher_disagreement_score":0.015060263,"about_ca_system_score_codex":0.000013326518,"about_ca_system_score_gemma":0.00003042948,"threshold_uncertainty_score":0.3169705},"labels":[],"label_agreement":null},{"id":"W4413516968","doi":"10.64628/aam.dmntjq7jd","title":"A year after the first CRISPR babies, stricter regulations are now in place","year":2019,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"CRISPR; Business; Internet privacy; Computer science; Genetics; Biology","score_opus":0.003480368783718787,"score_gpt":0.23537572654426886,"score_spread":0.23189535776055006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413516968","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944373,0.00033569292,0.0011184876,0.0011530427,0.00010223793,0.00015947154,0.0000068301574,0.0000084864905,0.002678488],"genre_scores_gemma":[0.9937637,0.000053413638,0.00023500761,0.00023881509,0.00007277483,0.000014759724,0.000010513037,0.000010919521,0.0056000846],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999568,0.000007698151,0.00008780982,0.00015240633,0.000055323715,0.00012875762],"domain_scores_gemma":[0.9996587,0.000008380927,0.0000140176135,0.00028055158,0.000017725964,0.000020597843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004700176,0.00007387949,0.000056529232,0.000022707285,0.000017093951,0.000015400108,0.00009129389,0.00006327739,0.00018147263],"category_scores_gemma":[0.0000100374,0.000053720087,0.000035328794,0.000067257395,0.000012482004,0.0000015682207,0.00005996742,0.000052960175,0.00006824835],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022001637,0.000105352934,0.88505685,0.00006982319,0.000079074045,0.000005310052,0.00048404725,0.015565974,0.041392162,0.00019853652,0.05629076,0.00053207553],"study_design_scores_gemma":[0.0005360686,0.000059706847,0.618311,0.000020700125,0.000009645232,0.000005341067,0.00032155492,0.0009857881,0.019079104,0.000019587278,0.36043268,0.00021884996],"about_ca_topic_score_codex":0.00001561502,"about_ca_topic_score_gemma":0.000995695,"teacher_disagreement_score":0.3041419,"about_ca_system_score_codex":0.0000070201695,"about_ca_system_score_gemma":0.000011122116,"threshold_uncertainty_score":0.21906415},"labels":[],"label_agreement":null},{"id":"W4413567530","doi":"10.64628/aam.yyr9qsa6p","title":"Meet the Canadian writers and researchers who deserve to win the Nobel Prize","year":2020,"lang":"en","type":"preprint","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Political science; Media studies; Sociology","score_opus":0.04438411764226231,"score_gpt":0.3461746658379614,"score_spread":0.3017905481956991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413567530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76631737,0.0066774655,0.008211302,0.1740816,0.0006691946,0.003050278,0.00023776815,0.00004490102,0.040710147],"genre_scores_gemma":[0.99442035,0.00015520476,0.00074907293,0.0028012542,0.00024770573,0.000065850574,0.000038506227,0.00003026998,0.0014917726],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99896914,0.000062968276,0.00012783331,0.0003962608,0.0001420274,0.00030179363],"domain_scores_gemma":[0.9990103,0.00002618013,0.000018548442,0.00057105755,0.0000543594,0.00031953386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031877845,0.00017938022,0.00012339102,0.000033414348,0.00015008992,0.00014596201,0.0005332132,0.00019901761,0.000020160127],"category_scores_gemma":[0.00019121103,0.000111485344,0.000068877154,0.00007483421,0.00008375695,6.912096e-7,0.0008305888,0.0003112195,0.0000062139343],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002570218,0.000043358097,0.008256714,0.00065279374,0.0015360487,0.000058310572,0.0067598154,0.022802122,0.3386024,0.004600969,0.60287994,0.013550492],"study_design_scores_gemma":[0.00078454823,0.00048073588,0.03333135,0.00016608865,0.00012923278,0.00003908215,0.0022044734,0.0057292497,0.12947847,0.0013250717,0.8247232,0.001608497],"about_ca_topic_score_codex":0.033741683,"about_ca_topic_score_gemma":0.33237115,"teacher_disagreement_score":0.29862946,"about_ca_system_score_codex":0.00003185402,"about_ca_system_score_gemma":0.00028407757,"threshold_uncertainty_score":0.9726927},"labels":[],"label_agreement":null},{"id":"W4413615921","doi":"10.1101/2025.08.21.671542","title":"Systematic Evaluation of Somatic Contamination in Germline Genomes","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Germline; Somatic cell; Contamination; Biology; Genome; Genetics; Germline mutation; Computational biology; Mutation; Ecology; Gene","score_opus":0.010730577468917606,"score_gpt":0.2745766710921844,"score_spread":0.26384609362326683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413615921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9789107,0.011572019,0.0075176302,0.000022668546,0.0004744387,0.0013887638,0.00006862143,0.000028274217,0.00001691915],"genre_scores_gemma":[0.9979783,0.00033270198,0.0011867208,0.000018614599,0.00010323336,0.0003383771,0.0000021483465,0.000030896543,0.000008982895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980597,0.00021004307,0.00068617304,0.00047604987,0.00034941293,0.00021860798],"domain_scores_gemma":[0.9982108,0.00003024035,0.00032083763,0.00081847963,0.0005662118,0.000053425192],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014326634,0.00028640067,0.00049412757,0.00027012173,0.000024183046,0.000027979599,0.0002808614,0.00036804986,0.000007688935],"category_scores_gemma":[0.0004995653,0.00031723204,0.00011405354,0.00021854907,0.0000312562,0.000004003646,0.00021981746,0.0001766255,0.0000025989996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010148344,0.00009068681,0.00259721,0.016210373,0.00017861999,0.0000018034375,0.000015587253,0.006893478,0.9739108,0.00006800401,0.000018753297,0.0000045265333],"study_design_scores_gemma":[0.0009387669,0.000053411422,0.05312592,0.0057062833,0.00042477428,1.3187292e-8,0.000010738992,0.020320743,0.91887814,0.0000036505112,0.000051713498,0.00048583982],"about_ca_topic_score_codex":0.000013682082,"about_ca_topic_score_gemma":0.00000967208,"teacher_disagreement_score":0.055032667,"about_ca_system_score_codex":0.00012247825,"about_ca_system_score_gemma":0.00045323605,"threshold_uncertainty_score":0.999928},"labels":[],"label_agreement":null},{"id":"W4413682268","doi":"10.12688/gatesopenres.16383.1","title":"A Culturally Grounded Method for Dialogue Between Indigenous Peoples and Researchers on Emerging Technologies: Lessons from the Gene Drive Context","year":2025,"lang":"en","type":"preprint","venue":"Gates Open Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nortel (Canada); Manitoba Health","funders":"Bill and Melinda Gates Foundation","keywords":"Indigenous; Context (archaeology); Grounded theory; Gene drive; Sociology; Qualitative research; Engineering ethics; Political science; Engineering; Social science; Geography; Gene; Biology; Archaeology; Genetics","score_opus":0.12979577916307777,"score_gpt":0.48846552019285877,"score_spread":0.358669741029781,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413682268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8787259,0.027952954,0.04704459,0.02686622,0.00036458566,0.012536867,0.0049568033,0.00012940276,0.001422707],"genre_scores_gemma":[0.9666531,0.009241647,0.017542625,0.000115340365,0.00036890237,0.002108373,0.0023522726,0.00006178476,0.001555949],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971715,0.0004679398,0.00030695286,0.0009544018,0.00036563555,0.0007335226],"domain_scores_gemma":[0.99681854,0.0015662209,0.000076846634,0.0010506941,0.00038944077,0.000098282224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002446309,0.00031887568,0.00043809932,0.00014722701,0.00059737527,0.0005315708,0.0023056436,0.0006021202,0.000005355522],"category_scores_gemma":[0.0020911011,0.00023827242,0.00013041598,0.00021162473,0.00026818676,0.000005097497,0.006035258,0.0011312689,0.0000030849938],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015211217,0.00026795242,0.0072194086,0.0014070089,0.0042997403,0.000029160874,0.024733627,0.0018962013,0.32950333,0.002746934,0.022003008,0.6043725],"study_design_scores_gemma":[0.0029743863,0.0013303382,0.012647787,0.0012952457,0.00021247173,0.000005706761,0.06012434,0.0007701872,0.8406739,0.022315543,0.056150485,0.0014995578],"about_ca_topic_score_codex":0.005821729,"about_ca_topic_score_gemma":0.0035826147,"teacher_disagreement_score":0.60287297,"about_ca_system_score_codex":0.00007794621,"about_ca_system_score_gemma":0.00055138237,"threshold_uncertainty_score":0.9716467},"labels":[],"label_agreement":null},{"id":"W4413799537","doi":"10.1101/2025.08.27.672191","title":"De novo engineered guide RNA-directed transposition with TnpB-family proteins reveals features of naturally evolved systems","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institutes of Health; National Science Foundation","keywords":"Transposition (logic); Computational biology; RNA; Biology; Genetics; Computer science; Gene; Artificial intelligence","score_opus":0.0048779152482186245,"score_gpt":0.22657481438372828,"score_spread":0.22169689913550966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413799537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9420975,0.0123485355,0.042360563,0.00005261596,0.0006243835,0.0014951982,0.0006913064,0.0002575607,0.000072370145],"genre_scores_gemma":[0.9815507,0.0004105808,0.017176282,0.000064477084,0.00031395475,0.00029728722,0.000008828383,0.00009077699,0.00008709342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99780387,0.000103105674,0.00053986383,0.00078250957,0.00029119468,0.00047948238],"domain_scores_gemma":[0.9978547,0.000021051024,0.00024676506,0.0010344894,0.00067464396,0.00016832621],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003310119,0.0005598157,0.000580477,0.00020736364,0.000066683475,0.000082839026,0.00049100356,0.0007606047,0.0000025545291],"category_scores_gemma":[0.0001113051,0.00056036364,0.0001756333,0.0003235632,0.000064684304,0.0000068485892,0.00013665721,0.0004907846,8.531302e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001286433,0.00006229196,0.0006027936,0.001321977,0.0003902153,0.000019930902,0.000010619196,0.0075019756,0.98945934,0.000063489955,0.00043631255,0.000002406049],"study_design_scores_gemma":[0.00071347086,0.00015191699,0.061570615,0.0012075274,0.00020902346,1.7172903e-7,0.0000051772927,0.00043510424,0.9336,3.3604834e-7,0.0014481965,0.00065847434],"about_ca_topic_score_codex":0.000117002724,"about_ca_topic_score_gemma":0.0000076099636,"teacher_disagreement_score":0.06096782,"about_ca_system_score_codex":0.00009572566,"about_ca_system_score_gemma":0.00063564524,"threshold_uncertainty_score":0.9996848},"labels":[],"label_agreement":null},{"id":"W4413817845","doi":"10.1073/pnas.2506257122","title":"TIGER: A tdTomato in vivo genome-editing reporter mouse for investigating precision-editor delivery approaches","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Eye Institute; Howard Hughes Medical Institute; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Human Genome Research Institute; School of Medicine, University of California, Irvine; Knights Templar Eye Foundation; University of California, Irvine; Research to Prevent Blindness; Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Genome editing; Biology; Reporter gene; In vivo; Cell biology; Green fluorescent protein; Transgene; Ex vivo; Genome; Gene delivery; Computational biology; Genetics; Gene; Transfection; Gene expression","score_opus":0.032584135786030345,"score_gpt":0.3158580566978753,"score_spread":0.28327392091184495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413817845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977637,0.00021337082,0.00006761634,0.00045310188,0.00005344887,0.00021261969,0.000010714576,0.000004326519,0.0012211101],"genre_scores_gemma":[0.99337256,0.000013333219,0.005935606,0.000099034914,0.00031130732,0.000033287295,4.3848777e-7,0.0000036689205,0.00023076226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906427,0.0000027782194,0.00030547063,0.00022575186,0.00028192173,0.0001198131],"domain_scores_gemma":[0.9996198,0.00004227529,0.00018396489,0.000010408454,0.00012500353,0.00001855309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008753775,0.000072446805,0.00009874517,0.000105521045,0.00008007898,0.000014835213,0.00034245104,0.00008487679,0.0000011346168],"category_scores_gemma":[0.0008566903,0.000056213867,0.000057784455,0.00027372618,0.00019514076,0.000015015043,0.0001322419,0.000057608115,4.5684686e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000058917085,0.000013905953,0.0062140333,0.00008602407,0.000010528024,1.2164371e-9,0.0000653831,0.0011914982,0.98998964,0.00073015294,0.0014727005,0.00022022355],"study_design_scores_gemma":[0.00014113686,0.000024372299,0.006505836,0.0000730646,0.00000556742,0.0000014938482,0.00022540957,0.0059122224,0.98361605,0.0022065763,0.0012249021,0.000063370906],"about_ca_topic_score_codex":0.0000018772012,"about_ca_topic_score_gemma":2.0819566e-7,"teacher_disagreement_score":0.00637361,"about_ca_system_score_codex":0.000012384283,"about_ca_system_score_gemma":0.000037636695,"threshold_uncertainty_score":0.22923349},"labels":[],"label_agreement":null},{"id":"W4413842505","doi":"10.1101/2025.08.30.672031","title":"ATAC-seq of Low-Input and Cryopreserved Primordial Germ Cells Reveals Functional Enhancers","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Naito Science and Engineering Foundation; Research Organization of Information and Systems","keywords":"Germ; Cryopreservation; Enhancer; Cell biology; RNA-Seq; Biology; Chemistry; Computational biology; Biochemistry; Transcriptome; Embryo; Gene; Transcription factor; Gene expression","score_opus":0.0076846302739431655,"score_gpt":0.2374428027936707,"score_spread":0.22975817251972752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413842505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98199314,0.0036021713,0.012000689,0.000047321733,0.0013499114,0.0004972852,0.00042409572,0.000053936856,0.000031422784],"genre_scores_gemma":[0.9950293,0.0009961955,0.00305607,0.00009107807,0.0005985516,0.00009151591,0.0000033765305,0.00005531591,0.00007862458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794966,0.00006703641,0.0004887532,0.00087578635,0.00023886611,0.00037989637],"domain_scores_gemma":[0.9982391,0.000030289304,0.00024008771,0.0009998804,0.00031780178,0.00017284218],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003296346,0.00043663895,0.00047246442,0.00014475,0.000069282585,0.00005262118,0.00035514144,0.0005866433,0.000027716751],"category_scores_gemma":[0.00012288925,0.0005031174,0.00017749632,0.00016678643,0.00011919197,0.0000061362043,0.0007655956,0.00034032913,0.0000036272593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060945953,0.000057331777,0.0019748253,0.0008433167,0.00019454131,0.000003842293,0.0000037282175,0.0010470971,0.99476343,0.00004167702,0.0010060277,0.0000032557316],"study_design_scores_gemma":[0.0004743904,0.000057738325,0.03358003,0.00026394127,0.00008249789,1.4444822e-8,0.0000015344393,0.00015451692,0.9622101,0.0000017451596,0.0027154034,0.00045807796],"about_ca_topic_score_codex":0.000023336226,"about_ca_topic_score_gemma":0.000003131571,"teacher_disagreement_score":0.032553304,"about_ca_system_score_codex":0.000048869875,"about_ca_system_score_gemma":0.00045205356,"threshold_uncertainty_score":0.99974203},"labels":[],"label_agreement":null},{"id":"W4413843105","doi":"10.1101/2025.08.25.672084","title":"Parasitism-mediated horizontal transfer of a functional cytochrome P450 gene entails transposon colonization in newly gained introns","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Akademie Věd České Republiky","keywords":"Transposable element; Horizontal gene transfer; Intron; Genetics; Biology; Gene; Colonization; Mutant; Genome; Microbiology","score_opus":0.006515236589134188,"score_gpt":0.23040883038017987,"score_spread":0.22389359379104568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413843105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88868326,0.0013022368,0.10805133,0.00007582099,0.00040367513,0.0006415175,0.0007829301,0.000053146694,0.0000060672983],"genre_scores_gemma":[0.99742997,0.0005094001,0.0014481683,0.00005634101,0.00026827937,0.000186195,0.00003723878,0.00005736578,0.0000070341243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979723,0.00008663904,0.0005745106,0.00073879823,0.00023416051,0.0003935534],"domain_scores_gemma":[0.9989579,0.000024675488,0.000094227624,0.0005611399,0.00023050724,0.0001315968],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023240644,0.00042475303,0.00047390087,0.00026472774,0.000047081805,0.000030605934,0.00027820322,0.0006592797,0.000028556315],"category_scores_gemma":[0.00007451933,0.00051926536,0.00017740382,0.00037880987,0.0000774053,0.0000076009505,0.00009887405,0.0003631013,0.0000032265918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015543315,0.00014569768,0.0033598414,0.0002631383,0.00016112882,0.000012804553,0.000013590903,0.0061378563,0.98962516,0.00006319945,0.000059336846,0.0000028301304],"study_design_scores_gemma":[0.0013698268,0.00016049367,0.15399966,0.00018526085,0.000093265226,4.6668454e-8,0.0000033809717,0.0007860405,0.84235495,6.3763446e-7,0.00059125293,0.000455174],"about_ca_topic_score_codex":0.000060084774,"about_ca_topic_score_gemma":0.00004517827,"teacher_disagreement_score":0.15063982,"about_ca_system_score_codex":0.00011341932,"about_ca_system_score_gemma":0.0005962466,"threshold_uncertainty_score":0.9997259},"labels":[],"label_agreement":null},{"id":"W4413924841","doi":"10.1093/brain/awaf264","title":"Variant-specific deep phenotyping as a tool to develop precision therapies","year":2025,"lang":"en","type":"article","venue":"Brain","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Precision medicine; MEDLINE; Medicine; Psychology; Computational biology; Biology; Pathology","score_opus":0.006604869967809203,"score_gpt":0.2852224083103362,"score_spread":0.278617538342527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413924841","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24655549,0.0030545478,0.7404733,0.0014461048,0.0002753244,0.00026811782,0.0000034446136,0.000032568692,0.007891147],"genre_scores_gemma":[0.96768224,0.0001341577,0.020723058,0.0022163156,0.00023740808,0.000049621736,0.00003378504,0.000026672813,0.00889673],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993525,0.00002140464,0.00013436523,0.00025448258,0.000064224645,0.0001730108],"domain_scores_gemma":[0.99961317,0.00002399273,0.000013238502,0.00025347105,0.00005966597,0.0000364589],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015760722,0.000106335814,0.00008538024,0.000054633387,0.000057545378,0.00003288759,0.000148442,0.00007930187,0.00006547824],"category_scores_gemma":[0.00022197017,0.00010487606,0.00003180656,0.00021345,0.000010929399,0.0000015196895,0.00011171682,0.00004613347,0.000061133054],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006828505,0.00001943406,0.000042515876,0.000012666204,0.000042729393,0.0000034256543,0.0002973579,0.00061033823,0.68143874,0.0016304718,0.017473234,0.29836082],"study_design_scores_gemma":[0.00028554263,0.000050193557,0.002585054,0.000030482564,0.0000036695621,0.000006896245,0.00010164066,0.00013151472,0.14539199,0.00041138072,0.85082775,0.00017391599],"about_ca_topic_score_codex":0.0000038430635,"about_ca_topic_score_gemma":0.000013741701,"teacher_disagreement_score":0.8333545,"about_ca_system_score_codex":0.000010531028,"about_ca_system_score_gemma":0.00005049854,"threshold_uncertainty_score":0.42767218},"labels":[],"label_agreement":null},{"id":"W4413969484","doi":"10.1016/j.cjca.2025.08.340","title":"Gene Replacement Therapy in Patients With Cardiac Disease: Challenges in Trial Design and Management of Adverse Events","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Sarnoff Cardiovascular Research Foundation; Bristol-Myers Squibb","keywords":"Medicine; Adverse effect; Intensive care medicine; Genetic enhancement; Internal medicine; Gene; Genetics","score_opus":0.011122179228361983,"score_gpt":0.25103672846583397,"score_spread":0.239914549237472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413969484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98707414,0.010070684,0.002107474,0.00007335057,0.00021886753,0.00032574587,0.0000061698215,3.7310326e-7,0.00012321712],"genre_scores_gemma":[0.99471205,0.004856804,0.0003392786,0.000010222467,0.000044490116,0.000010206432,0.0000050803956,0.0000052410055,0.00001661147],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99941427,0.00008966564,0.00019397761,0.00011665739,0.00004835804,0.00013705897],"domain_scores_gemma":[0.99968135,0.0000073249585,0.000047772555,0.000126276,0.000042075375,0.00009517994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025775997,0.00007512892,0.00020368096,0.00014834022,0.000009612608,8.327821e-7,0.00007289425,0.000049279264,6.1170584e-7],"category_scores_gemma":[0.000011323898,0.000066664936,0.000045149543,0.00005139627,0.000027894352,0.0000018908357,0.000011882863,0.000048414317,4.3484455e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0345282,0.000038300277,0.8573524,0.0001417141,0.0012000342,0.00008291333,0.00012939042,0.07469807,0.00070146244,0.000117297335,0.00038109146,0.030629173],"study_design_scores_gemma":[0.019367313,0.001269747,0.97160167,0.00009298045,0.00003923325,0.0000014158799,0.000085506996,0.0000057143598,0.00074585486,0.000036220536,0.006650902,0.000103445],"about_ca_topic_score_codex":0.000024844707,"about_ca_topic_score_gemma":0.00009196885,"teacher_disagreement_score":0.11424931,"about_ca_system_score_codex":0.000030409086,"about_ca_system_score_gemma":0.0001654759,"threshold_uncertainty_score":0.27185172},"labels":[],"label_agreement":null},{"id":"W4413980850","doi":"10.1073/pnas.2426094122","title":"A general genome editing strategy using CRISPR lipid nanoparticle spherical nucleic acids","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Institute for Nanotechnology","funders":"Air Force Office of Scientific Research; Division of Materials Research; Division of Electrical, Communications and Cyber Systems; Northwestern University; International Institute for Nanotechnology, Northwestern University; Air Force Research Laboratory; National Science Foundation","keywords":"CRISPR; Genome editing; Nucleic acid; Computational biology; Gene delivery; Guide RNA; Genome; DNA; Transfection; Genome engineering; Chemistry; Biology; Gene; Genetics","score_opus":0.023797713591605037,"score_gpt":0.33400066807545975,"score_spread":0.3102029544838547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413980850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99728656,0.00027214197,0.00012132904,0.00035813823,0.000032545733,0.00007383105,0.0000043563023,0.0000046375553,0.0018464813],"genre_scores_gemma":[0.995351,0.00001537228,0.0041300766,0.00014980207,0.00021519087,0.0000030593578,1.589344e-7,0.0000035504086,0.00013176483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913657,0.0000037996037,0.00021336545,0.00019475372,0.00030129458,0.00015019994],"domain_scores_gemma":[0.9997271,0.000009008539,0.000104588806,0.0000092326645,0.00012530157,0.000024789422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038846023,0.00007458619,0.00009160888,0.000045177632,0.000120138146,0.000020186575,0.0003766683,0.00006978606,0.0000061893093],"category_scores_gemma":[0.0001570389,0.00005793525,0.000059534108,0.00036889984,0.00026304752,0.000013756856,0.0001567352,0.00007172406,2.5131172e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000058977926,0.00001547251,0.002706114,0.000026186723,0.0000116421,2.5823899e-9,0.000018740708,0.0047755735,0.9902412,0.0018956275,0.00013199457,0.00017152651],"study_design_scores_gemma":[0.00011350458,0.00003786181,0.019553147,0.000024052866,0.000010097835,0.0000038629128,0.00010848858,0.006264924,0.97209936,0.0012325578,0.00049038633,0.000061740655],"about_ca_topic_score_codex":0.00000364914,"about_ca_topic_score_gemma":5.9935346e-8,"teacher_disagreement_score":0.018141847,"about_ca_system_score_codex":0.000013245257,"about_ca_system_score_gemma":0.00003772013,"threshold_uncertainty_score":0.2362531},"labels":[],"label_agreement":null},{"id":"W4413981845","doi":"10.1186/s44149-025-00188-5","title":"Rapid detection of Chinese sacbrood virus via CRISPR-Cas13a-based lateral flow strips","year":2025,"lang":"en","type":"article","venue":"Animal Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China","keywords":"CRISPR; Virology; Biology; Genetics; Gene","score_opus":0.004015239488263331,"score_gpt":0.26878396672044746,"score_spread":0.26476872723218414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413981845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9720595,0.003972031,0.023410909,0.000025266187,0.00014499138,0.0001173459,0.00010499551,0.000024676732,0.00014031467],"genre_scores_gemma":[0.99934167,0.00007527444,0.00020223581,0.00010312099,0.00010426664,0.000016505175,0.0000881724,0.000013310049,0.000055435572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934405,0.000029135344,0.00016637608,0.0002238825,0.00007840761,0.0001581211],"domain_scores_gemma":[0.99962336,0.000013536772,0.00003204502,0.00021582675,0.00005168383,0.00006357449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000034726465,0.00014119915,0.00013353948,0.000060735485,0.00005249165,0.000012556767,0.00010189305,0.00007552861,0.000031272855],"category_scores_gemma":[0.000067113106,0.00013272508,0.00013474766,0.00012423642,0.000033450986,0.0000031512236,0.00004405132,0.00005202831,0.0000030650135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003550263,0.0001047765,0.009079747,0.00007780669,0.000053183092,0.000002330818,0.000007444542,0.00070046575,0.9829254,0.0000024684261,0.00019188854,0.0064994246],"study_design_scores_gemma":[0.00057777006,0.00033587054,0.23623699,0.000016121803,0.000053118572,0.0000011666565,0.0000074858285,0.0042160708,0.7565963,0.000034852983,0.0017794161,0.00014478157],"about_ca_topic_score_codex":0.000029794699,"about_ca_topic_score_gemma":0.000041226078,"teacher_disagreement_score":0.22715725,"about_ca_system_score_codex":0.000007636064,"about_ca_system_score_gemma":0.00004277395,"threshold_uncertainty_score":0.5412372},"labels":[],"label_agreement":null},{"id":"W4414028926","doi":"10.1101/2025.09.02.671676","title":"High-fidelity CRISPR genome editing of single-nucleotide mutation with near-complementary guide RNA via enhanced target binding kinetics","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kootenay Association for Science & Technology","funders":"National Research Foundation of Korea; National Research Foundation","keywords":"CRISPR; Genome editing; Nucleotide; Computational biology; RNA; Genetics; Mutation; Kinetics; RNA editing; Guide RNA; Biology; Gene; Physics","score_opus":0.007753330244718029,"score_gpt":0.24548862772154817,"score_spread":0.23773529747683014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414028926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77866673,0.00070259563,0.21847966,0.000060265415,0.00088695745,0.00056612137,0.00052774826,0.00008638852,0.000023532211],"genre_scores_gemma":[0.91558284,0.00009212536,0.08328181,0.000099959165,0.0007315307,0.00007217385,0.0000291796,0.0001003577,0.000010015268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969807,0.00009300317,0.0009190069,0.0010444099,0.00037105085,0.0005917925],"domain_scores_gemma":[0.9974826,0.00003209406,0.00056337845,0.0011075576,0.0006333329,0.00018103138],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041769457,0.0006155351,0.00061357534,0.00019103107,0.00014183622,0.000102731414,0.0005292214,0.00040119365,0.000026317708],"category_scores_gemma":[0.00013343774,0.0006949427,0.00016722192,0.00033002277,0.0001397574,0.0000124290555,0.00059571554,0.00039935388,0.000004070568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049498696,0.000113792696,0.0005705626,0.00055453926,0.00028082426,0.000013551146,0.000015244999,0.012555451,0.9856966,0.0000122087795,0.00012320967,0.000014518843],"study_design_scores_gemma":[0.00064467185,0.00025133073,0.005731187,0.00032852884,0.00016762943,5.0949193e-8,0.000013895056,0.0005433274,0.9892379,0.0000018857364,0.002423979,0.0006556082],"about_ca_topic_score_codex":0.00015323317,"about_ca_topic_score_gemma":0.000016046135,"teacher_disagreement_score":0.13691613,"about_ca_system_score_codex":0.00016175056,"about_ca_system_score_gemma":0.00030825267,"threshold_uncertainty_score":0.99955016},"labels":[],"label_agreement":null},{"id":"W4414043422","doi":"10.1101/2025.09.02.673780","title":"BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Montreal General Hospital; Vancouver Foundation; McGill University; McGill University Health Centre","funders":"","keywords":"Wnt signaling pathway; Druggability; Cancer; Drug resistance; Combination therapy; Gene; Drug; Rational design; Colorectal cancer","score_opus":0.010298111478509687,"score_gpt":0.2679164827224003,"score_spread":0.25761837124389064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414043422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8713002,0.0029060873,0.122306734,0.00019083719,0.00090198696,0.0015090022,0.00079106085,0.00008560118,0.0000084661],"genre_scores_gemma":[0.9886985,0.0006539729,0.008208683,0.00014973883,0.00056229444,0.001584058,0.0000130263,0.00007143433,0.000058330777],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831724,0.000024982219,0.00035627212,0.00072785123,0.00021456262,0.00035906606],"domain_scores_gemma":[0.9987526,0.000031109343,0.0001978622,0.00062216975,0.00030013153,0.000096120675],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022224004,0.00041121372,0.00030532668,0.000121273486,0.00016112284,0.0001240493,0.0003273514,0.00044388988,0.000011894677],"category_scores_gemma":[0.00014183384,0.00043355185,0.00017113781,0.00011560618,0.00004326339,0.000013588325,0.00036863988,0.00024156664,0.000001253981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008270186,0.00006391568,0.0016826971,0.00044844206,0.00017727017,8.003937e-7,0.000011113902,0.0029909608,0.99384433,0.00016487199,0.00052560825,0.0000072577454],"study_design_scores_gemma":[0.00075595843,0.00006566342,0.0152169885,0.00043167188,0.000052331372,6.6604233e-9,0.0000029983555,0.0013548433,0.9713376,0.000008951547,0.010260961,0.00051202194],"about_ca_topic_score_codex":0.000030637777,"about_ca_topic_score_gemma":0.0000060666907,"teacher_disagreement_score":0.11739823,"about_ca_system_score_codex":0.00011098355,"about_ca_system_score_gemma":0.00047233843,"threshold_uncertainty_score":0.99981165},"labels":[],"label_agreement":null},{"id":"W4414048656","doi":"10.1021/acssynbio.5c00412","title":"Genetic Entanglement Enables Ultrastable Biocontainment in the Mammalian Gut","year":2025,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Stalemate; Stepping stone; Plasmid; Reverse genetics; Zebrafish; Caenorhabditis elegans","score_opus":0.0056073508518355636,"score_gpt":0.29605801251499664,"score_spread":0.2904506616631611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414048656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9775204,0.0042104195,0.011534847,0.0016033036,0.00034638544,0.00049912685,0.000019820885,0.00001411774,0.0042515956],"genre_scores_gemma":[0.99759483,0.00031097786,0.0005760789,0.00080031995,0.0000790338,0.00012817043,0.000034479785,0.000011161389,0.00046496402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880916,0.00011888492,0.0002610806,0.0003619153,0.00006280624,0.00038613947],"domain_scores_gemma":[0.9994028,0.000040298757,0.000034445962,0.00046999045,0.000021126989,0.000031313455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002893347,0.00017364185,0.000151206,0.000078834026,0.00006494239,0.0000191887,0.00037320328,0.00014655846,0.000042519332],"category_scores_gemma":[0.000053155316,0.0001305142,0.000060130056,0.000136636,0.000094300674,0.0000012161701,0.00010897222,0.000094317875,0.00001074882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003543535,0.00012743793,0.015429505,0.000034823497,0.0000597965,0.000007191929,0.00017295078,0.00025478215,0.96664274,0.0020935,0.0014347809,0.013707074],"study_design_scores_gemma":[0.001168989,0.00049839704,0.042717922,0.000051846462,0.00006319982,0.000052146395,0.0013695791,0.00007696209,0.51844513,0.0016127679,0.43348202,0.00046104533],"about_ca_topic_score_codex":0.000117881675,"about_ca_topic_score_gemma":0.00018980945,"teacher_disagreement_score":0.4481976,"about_ca_system_score_codex":0.000024786745,"about_ca_system_score_gemma":0.00004563977,"threshold_uncertainty_score":0.5322215},"labels":[],"label_agreement":null},{"id":"W4414053788","doi":"10.1021/acsomega.5c01294","title":"Application of Gene Editing Technology Based on Targeted Delivery Materials in TNBC","year":2025,"lang":"en","type":"review","venue":"ACS Omega","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Science Foundation of Sichuan Province","keywords":"Genome editing; CRISPR; Cas9; RNA interference; Gene delivery; Genetic enhancement; Viral vector; Gene","score_opus":0.006817038113877607,"score_gpt":0.29891800322811724,"score_spread":0.2921009651142396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414053788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020410467,0.9933345,0.0036821724,0.000013669146,0.00019693513,0.00047579873,0.000115233874,0.000017896182,0.00012279066],"genre_scores_gemma":[0.037427958,0.95980847,0.0011592527,0.000030442377,0.00019851091,0.00024667496,0.0010412604,0.00003365376,0.00005377943],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99899787,0.000031616666,0.00039743257,0.00033195567,0.000069181064,0.0001719695],"domain_scores_gemma":[0.99933225,0.000023167036,0.00014728602,0.00043759285,0.000040986157,0.00001869759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013554274,0.00020947492,0.00055538426,0.00032145216,0.000014693258,0.0000056055605,0.00024116262,0.0004627402,0.0000018682738],"category_scores_gemma":[0.00010221994,0.00020686834,0.000091825066,0.0003093469,0.00002460541,7.867104e-7,0.00007198145,0.00010629723,0.0000036402803],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014929904,0.00007344461,0.000019750734,0.00951872,0.00007141042,0.000005502443,0.0000035901567,0.00047792876,0.2061162,0.0000433622,0.0002668997,0.78338826],"study_design_scores_gemma":[0.00027581185,0.00010262254,0.000013768464,0.0025933154,0.000107948596,0.0000037326354,0.000006171037,0.000038608912,0.3833303,0.0000116957735,0.6132194,0.00029663087],"about_ca_topic_score_codex":0.000008864249,"about_ca_topic_score_gemma":0.000004245203,"teacher_disagreement_score":0.78309166,"about_ca_system_score_codex":0.000021592308,"about_ca_system_score_gemma":0.00010032971,"threshold_uncertainty_score":0.8435846},"labels":[],"label_agreement":null},{"id":"W4414090851","doi":"10.1016/j.tplants.2025.08.011","title":"Hybrid AI in synthetic biology: next era in agriculture","year":2025,"lang":"en","type":"review","venue":"Trends in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Synthetic biology; Trait; Automation; Agriculture; Key (lock); Plant biology","score_opus":0.0166434324834271,"score_gpt":0.35080426894567796,"score_spread":0.33416083646225087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414090851","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00096192234,0.9969106,0.00005750831,0.000029878971,0.00032589227,0.00015134786,0.00011470677,0.000007962509,0.00144019],"genre_scores_gemma":[0.010355489,0.98863643,0.00014322836,0.000041288327,0.000050839197,0.00005465395,0.0003252566,0.000008630366,0.00038420362],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983478,0.00005344088,0.00037920373,0.0006857216,0.00010124729,0.0004325763],"domain_scores_gemma":[0.99950475,0.000032513883,0.000058040332,0.00034019543,0.000012252914,0.0000522676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038516455,0.0002738655,0.00056446844,0.0007677298,0.000026889842,0.000030748193,0.0006352307,0.00020885564,0.0000079737765],"category_scores_gemma":[0.00009633848,0.00021199665,0.00009897811,0.0011345993,0.00013014121,0.000004661827,0.00020789125,0.000367816,0.000004008846],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000044146423,0.000057720055,0.00011142267,0.0010117986,0.0000071276786,0.00005155723,0.000024300043,0.00019189477,0.0029347914,0.00010160826,0.0006507418,0.9948526],"study_design_scores_gemma":[0.00027362377,0.00007095191,0.00052680983,0.0063969423,0.000032192744,0.0001321151,0.0000132570285,0.00011994124,0.0016144847,0.0000328866,0.99016446,0.0006223217],"about_ca_topic_score_codex":0.000041743184,"about_ca_topic_score_gemma":0.00028492245,"teacher_disagreement_score":0.99423033,"about_ca_system_score_codex":0.00006222145,"about_ca_system_score_gemma":0.00022808828,"threshold_uncertainty_score":0.86449724},"labels":[],"label_agreement":null},{"id":"W4414158242","doi":"10.1101/2025.09.08.674725","title":"Optimized CRISPR/Cas9 Electroporation and Single Cell Cloning Protocol for Generating Pure Cellular Models in Human Immortalized Myoblasts","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Courtois Foundation; Muscular Dystrophy Canada","keywords":"Electroporation; Cell sorting; Sanger sequencing; Transfection; C2C12; Genome editing; Cell culture; Myocyte; Cloning (programming); HEK 293 cells","score_opus":0.01318728626969423,"score_gpt":0.27721816930309545,"score_spread":0.2640308830334012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414158242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.55891556,0.0008221187,0.3934034,0.000040153613,0.00020615167,0.04635354,0.00011382842,0.00011806455,0.000027147169],"genre_scores_gemma":[0.8825712,0.00003345954,0.050301705,0.00006441107,0.00041668976,0.06645014,0.000011647702,0.0001248541,0.000025861496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99735785,0.000099369376,0.00067140785,0.0011264881,0.00018200563,0.0005628665],"domain_scores_gemma":[0.9985205,0.000016986034,0.00030790607,0.0007284766,0.00028958026,0.00013653215],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004620665,0.0005811161,0.0005359254,0.00022290202,0.00017870727,0.00020440834,0.00029904643,0.0006808052,0.0000045273255],"category_scores_gemma":[0.00007694618,0.0006834874,0.0001562005,0.0001934695,0.00004905535,0.000015498657,0.00036829652,0.00040254535,3.5860472e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009509543,0.00011449013,0.00013429856,0.00081725756,0.000055009095,0.00000623447,0.000010948663,0.044740576,0.95377886,0.000084827414,0.00016037247,0.000002002947],"study_design_scores_gemma":[0.0023146456,0.00018189625,0.00011078095,0.00023516858,0.000057940342,1.9583622e-8,0.000004242088,0.038443502,0.9570234,0.0000070080637,0.00095626316,0.00066516496],"about_ca_topic_score_codex":0.00002634061,"about_ca_topic_score_gemma":0.000009925772,"teacher_disagreement_score":0.3431017,"about_ca_system_score_codex":0.00009960937,"about_ca_system_score_gemma":0.00030832118,"threshold_uncertainty_score":0.9995616},"labels":[],"label_agreement":null},{"id":"W4414167871","doi":"10.1016/j.celrep.2025.116288","title":"Evolution of a melanoma that escapes allogeneic rejection","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; King Abdulaziz University; University College London; Horizon 2020 Framework Programme; UK Research and Innovation; Wellcome Trust; Francis Crick Institute; European Research Council; Cancer Research UK; Ministry of Education – Kingdom of Saudi Arabi; Prince Sattam bin Abdulaziz University","keywords":"Major histocompatibility complex; Melanoma; Downregulation and upregulation; Immune system; MHC class I; Transplantation; Retinoic acid; Cancer","score_opus":0.004316161528041072,"score_gpt":0.24706293183796205,"score_spread":0.24274677030992098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414167871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9579201,0.0037219687,0.027968714,0.00001262287,0.0003797052,0.00008810926,7.609946e-7,0.000010702398,0.009897351],"genre_scores_gemma":[0.99704826,0.00008745877,0.00034508033,0.000011595341,0.000044782166,0.000007651268,0.000016920005,0.0000063159578,0.0024319233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995094,0.000009574389,0.00015194753,0.00018195553,0.000055531058,0.00009162149],"domain_scores_gemma":[0.9996304,0.0000030373235,0.00006335075,0.00024707857,0.000036240595,0.000019908817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009078702,0.00006749048,0.00007642286,0.00004553942,0.000022281321,0.00000408274,0.000036572834,0.00008259242,0.0000074642135],"category_scores_gemma":[0.000024568479,0.0000686007,0.000059596798,0.000067051245,0.000016260205,0.0000010162564,0.000037349506,0.000028024368,6.343848e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008772333,0.000021338945,0.021373946,0.0000404937,0.000015855738,0.0000069829343,0.000009314354,0.0010992001,0.9756722,0.000016173628,0.0009255841,0.00081017456],"study_design_scores_gemma":[0.00007838663,0.000045043354,0.019370247,0.000012363124,0.000018502242,0.00003117399,0.000036267524,0.00006379969,0.96395445,0.00009648202,0.01622794,0.000065334745],"about_ca_topic_score_codex":0.000025693413,"about_ca_topic_score_gemma":0.000016600336,"teacher_disagreement_score":0.039128207,"about_ca_system_score_codex":0.000013524063,"about_ca_system_score_gemma":0.000050508683,"threshold_uncertainty_score":0.27974552},"labels":[],"label_agreement":null},{"id":"W4414203479","doi":"10.3390/cimb47090756","title":"Checkpoint-Dependent Sensitivities to Nucleoside Analogues Uncover Specific Patterns of Genomic Instability","year":2025,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; University College London; Toronto Metropolitan University","keywords":"Nucleoside; Nucleoside analogue; DNA replication; DNA; Genome instability; Mutagenesis; Thymidine; Mutant","score_opus":0.02041089845792492,"score_gpt":0.3874967529016425,"score_spread":0.36708585444371755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414203479","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0126076415,0.96885675,0.016244017,0.000014530947,0.0009014518,0.0007773547,0.00047974839,0.000015042436,0.000103448205],"genre_scores_gemma":[0.008765749,0.9891698,0.0005470703,0.000024851743,0.00019337347,0.00008362803,0.0010883431,0.00005066882,0.00007655581],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99727523,0.00033515805,0.0008874193,0.00092630775,0.000114951836,0.0004609348],"domain_scores_gemma":[0.99866843,0.000049358914,0.00018772017,0.0009217263,0.00007779568,0.00009497527],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033986117,0.0005615735,0.0014168267,0.00037308116,0.000023260138,0.000017124863,0.00048870605,0.0004636346,0.000022984908],"category_scores_gemma":[0.00013045827,0.0005478861,0.00048491312,0.00019435107,0.00009318839,0.0000021479711,0.0006644224,0.00032220306,0.000015216545],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049236838,0.0002995486,0.0010020789,0.019107623,0.00031585008,0.000037094625,0.0001882834,0.000346611,0.088051714,0.00040396777,0.00032518202,0.8898728],"study_design_scores_gemma":[0.00023620203,0.00018120342,0.00017445225,0.003039002,0.00012375513,0.000012678455,0.000041671537,0.0000017597375,0.020534888,0.00007541242,0.97496754,0.00061141077],"about_ca_topic_score_codex":0.000055351415,"about_ca_topic_score_gemma":0.00010048389,"teacher_disagreement_score":0.9746424,"about_ca_system_score_codex":0.00008593188,"about_ca_system_score_gemma":0.0001665475,"threshold_uncertainty_score":0.99969727},"labels":[],"label_agreement":null},{"id":"W4414258298","doi":"10.1101/2025.09.11.675687","title":"A Mammalian Genomic Signature Shaped by Single Nucleotide Variants Regulates Transcriptome Integrity and Diversity","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Transcriptome; Gene; Alternative splicing; RNA splicing; splice; Intron; Genomics; Single-nucleotide polymorphism; Genetic association","score_opus":0.008164486782803036,"score_gpt":0.2193794490813949,"score_spread":0.21121496229859185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414258298","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98672533,0.00633133,0.0045929886,0.0001680653,0.00075940794,0.0004516502,0.0008499336,0.000104859675,0.000016427224],"genre_scores_gemma":[0.99662095,0.0005535356,0.0022217673,0.00019474696,0.00026321897,0.000025359277,0.0000049208215,0.000059175964,0.000056327375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979186,0.00007800127,0.00031621955,0.0010510623,0.00018127385,0.00045482424],"domain_scores_gemma":[0.99866825,0.000014428732,0.00012779524,0.00078599865,0.00017562586,0.0002278843],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027142157,0.0005253805,0.00042669423,0.000120794735,0.00020090298,0.00012010938,0.0005198208,0.0008770835,0.000017811333],"category_scores_gemma":[0.000065868706,0.0006082014,0.00015308686,0.0001540566,0.000110385154,0.000008257996,0.0011689828,0.00075359864,0.0000032737653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005074774,0.00008105658,0.0030552123,0.00030373878,0.00018301059,0.000011028544,0.000015643105,0.000033731383,0.9951425,0.000022914732,0.0010960861,0.000004286785],"study_design_scores_gemma":[0.0007776346,0.00011616178,0.073382005,0.00023323436,0.00022304752,5.7762033e-8,0.0000073989736,0.00034293212,0.914424,0.000004565025,0.009485257,0.0010037004],"about_ca_topic_score_codex":0.00008491309,"about_ca_topic_score_gemma":0.0000096288395,"teacher_disagreement_score":0.08071853,"about_ca_system_score_codex":0.00008209616,"about_ca_system_score_gemma":0.00016834239,"threshold_uncertainty_score":0.99963695},"labels":[],"label_agreement":null},{"id":"W4414258336","doi":"10.1101/2025.09.11.675438","title":"Choosing the Best Route: Comparative Optimization of Wheat Transformation Methods for Improving Yield by Targeting <i>TaARE1-D</i> with CRISPR/Cas9","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Transformation (genetics); Yield (engineering); Callus; Regulator; Mutant; Grain yield","score_opus":0.012854598774557215,"score_gpt":0.2951838524195236,"score_spread":0.2823292536449664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414258336","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.042542383,0.0037980787,0.95159435,0.00012320014,0.00036044963,0.0011557285,0.0003574949,0.00004580816,0.000022507385],"genre_scores_gemma":[0.83302754,0.00023002135,0.16614953,0.00008011687,0.00017200418,0.00026914038,0.000012305297,0.00005168596,0.0000076861215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828506,0.00010668761,0.00052181835,0.00058533036,0.000152762,0.0003483362],"domain_scores_gemma":[0.99839914,0.00008716751,0.00032377578,0.0005889423,0.00052027556,0.0000806718],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006499493,0.00041876067,0.00043527022,0.00009124435,0.0001949079,0.000098390956,0.00036598198,0.00037976072,0.000003107706],"category_scores_gemma":[0.00014807524,0.00036181198,0.0001462079,0.00021752593,0.00007804964,0.000016428157,0.00015365239,0.00032103382,2.6191216e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079757505,0.000047394424,0.00011034671,0.0006387812,0.00014121736,1.8512911e-7,0.000057465066,0.076857075,0.92179734,0.00002862501,0.00021091894,0.000030904313],"study_design_scores_gemma":[0.00042528097,0.00014126163,0.00006811598,0.0002851163,0.00021858161,1.8399573e-8,0.000057606405,0.03634531,0.95911527,3.093332e-7,0.002935165,0.0004079755],"about_ca_topic_score_codex":0.000055135428,"about_ca_topic_score_gemma":0.0000040750556,"teacher_disagreement_score":0.79048514,"about_ca_system_score_codex":0.00005901643,"about_ca_system_score_gemma":0.00028091492,"threshold_uncertainty_score":0.9998834},"labels":[],"label_agreement":null},{"id":"W4414259389","doi":"10.1101/2025.09.13.672380","title":"In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Excitatory postsynaptic potential; Electroporation; Inhibitory postsynaptic potential; Neurotransmission; Cortical neurons; Cortex (anatomy); Premovement neuronal activity; Cerebral cortex; Cellular neuroscience","score_opus":0.013084221011700009,"score_gpt":0.2557896102739999,"score_spread":0.24270538926229987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414259389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9183425,0.00073939265,0.079288095,0.000032164357,0.0009193204,0.000497056,0.00013715636,0.000035841535,0.000008508203],"genre_scores_gemma":[0.9852459,0.00006679874,0.013609465,0.00010620006,0.0008417537,0.000053875505,0.0000022163256,0.00006382572,0.00000998857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767464,0.00014679396,0.0006774943,0.00079783023,0.00025791017,0.0004453309],"domain_scores_gemma":[0.9985541,0.000022037519,0.00029492276,0.0006416433,0.0003373569,0.00014995132],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000383314,0.0003848447,0.00040894438,0.0002608649,0.00006818519,0.000049328006,0.00027336332,0.00043362135,0.0000071353625],"category_scores_gemma":[0.00023610466,0.0005044998,0.00012451045,0.00033824702,0.00005278228,0.0000125039405,0.00029630662,0.00039448234,0.0000015920559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049380065,0.00009640901,0.0010367741,0.0002716188,0.000030664676,0.00001264571,0.0000123853215,0.02308152,0.97521573,0.000021776856,0.00017015696,9.089358e-7],"study_design_scores_gemma":[0.00035652757,0.0001411245,0.0018972071,0.00019194452,0.000058466674,4.0912724e-8,0.000006385029,0.00525649,0.9912547,7.184475e-7,0.00043240844,0.00040401434],"about_ca_topic_score_codex":0.000048205296,"about_ca_topic_score_gemma":0.00001177696,"teacher_disagreement_score":0.066903405,"about_ca_system_score_codex":0.00016657343,"about_ca_system_score_gemma":0.00045239515,"threshold_uncertainty_score":0.99974066},"labels":[],"label_agreement":null},{"id":"W4414316140","doi":"10.5376/cmb.2024.14.0027","title":"Off-Target Effects in Genome Editing: A Systematic Review of Prediction and Mitigation Strategies","year":2024,"lang":"en","type":"review","venue":"Computational Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genome; Genomics; Human genome; Context (archaeology); Identification (biology)","score_opus":0.006641624782293781,"score_gpt":0.3396840854121475,"score_spread":0.3330424606298537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414316140","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003525823,0.9250456,0.07358937,0.000011100417,0.00016090176,0.0010093974,0.0000939306,0.00001099762,0.00004342014],"genre_scores_gemma":[0.0017226301,0.99370635,0.0015894974,0.000047513888,0.00009768154,0.00022065113,0.0025745912,0.00003333666,0.000007763485],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9984912,0.00021968165,0.0006606372,0.00039168462,0.00008909923,0.00014766054],"domain_scores_gemma":[0.9994594,0.00005418756,0.00020126843,0.00017444813,0.00007111184,0.000039606624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025519112,0.00026886366,0.000959056,0.00016473616,0.000013887991,0.00001419723,0.00012086941,0.00025867176,0.0000015143127],"category_scores_gemma":[0.00016906936,0.00023249218,0.00020173955,0.00016817999,0.00006150025,0.000002469516,0.0000945161,0.00013973401,0.000003000918],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000011038019,0.000013943688,0.000001389645,0.99405324,0.00022172429,0.000008812764,0.0000103668435,0.00033598195,0.0006635667,0.0020193236,0.000030176643,0.0026403686],"study_design_scores_gemma":[0.00044168785,0.00065502507,0.000025574042,0.9541787,0.0029946198,0.0003796958,0.000029705341,0.0013524499,0.00013772477,0.014906244,0.024074368,0.00082419516],"about_ca_topic_score_codex":0.000001096927,"about_ca_topic_score_gemma":6.001874e-7,"teacher_disagreement_score":0.07199987,"about_ca_system_score_codex":0.000020970801,"about_ca_system_score_gemma":0.00015175469,"threshold_uncertainty_score":0.9480756},"labels":[],"label_agreement":null},{"id":"W4414348199","doi":"10.1073/pnas.2504318122","title":"The potential impacts of human genetics on virus emergence","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Agence Nationale de la Recherche; American Lung Association; National Institute of Neurological Disorders and Stroke","keywords":"Virus; Human genetics; Identification (biology); Genotype; Disease; Mutation; Viral evolution; Genomics; Human evolutionary genetics","score_opus":0.015771377819066942,"score_gpt":0.3486850183705426,"score_spread":0.33291364055147565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414348199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963727,0.0007077799,0.000011956739,0.00051882945,0.000032847976,0.00007296267,0.0000062058807,0.0000014885177,0.0022752245],"genre_scores_gemma":[0.99933285,0.00024632743,0.00016263472,0.00007080974,0.00004403307,0.0000024245878,1.1838998e-7,0.0000018152163,0.00013901107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992557,0.0000029821088,0.00018901179,0.00011936975,0.00034167292,0.000091253845],"domain_scores_gemma":[0.99969065,0.0000139618605,0.00013239775,0.000011379285,0.00013819305,0.000013421583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004523376,0.00005447644,0.000060575312,0.00004381121,0.00014406237,0.000007711343,0.00052863394,0.00005090486,0.0000020233326],"category_scores_gemma":[0.00016666457,0.000033251956,0.000056504614,0.00022409012,0.00035750627,0.0000035134242,0.0001240385,0.00005539195,1.168213e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008244495,0.00001339972,0.0011828202,0.000019292134,0.000012662024,6.192427e-10,0.000014603825,0.0006267762,0.99179184,0.0052785184,0.00076029985,0.00029155158],"study_design_scores_gemma":[0.00006336626,0.000066705245,0.057342235,0.000026058879,0.0000064851406,5.48453e-7,0.00005036297,0.00023838914,0.93783146,0.0040269657,0.00031543063,0.000031991018],"about_ca_topic_score_codex":0.0000031571517,"about_ca_topic_score_gemma":2.528123e-7,"teacher_disagreement_score":0.056159418,"about_ca_system_score_codex":0.000003733794,"about_ca_system_score_gemma":0.000021886612,"threshold_uncertainty_score":0.13559754},"labels":[],"label_agreement":null},{"id":"W4414358323","doi":"10.1038/s41551-025-01512-7","title":"Spatial profiling of gene editing by in situ sequencing in mice and macaques","year":2025,"lang":"en","type":"article","venue":"Nature Biomedical Engineering","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Science Foundation; National Institutes of Health; Helmut Horten Stiftung; National Institute of Allergy and Infectious Diseases; Universität Zürich; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Leverage (statistics); Genome editing; Guide RNA; RNA editing; In situ; Ex vivo; RNA; Gene","score_opus":0.0019350967698730202,"score_gpt":0.25245446978459546,"score_spread":0.25051937301472244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414358323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94422096,0.006736594,0.048357308,0.00008060574,0.0003446729,0.00011512431,0.000008664763,0.000014526092,0.00012152678],"genre_scores_gemma":[0.9924351,0.000098318356,0.007224001,0.000041423486,0.000115648494,0.000008110467,0.00005306348,0.0000111178015,0.000013235301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924123,0.000008945367,0.00023118872,0.00022086473,0.00009735464,0.00020042993],"domain_scores_gemma":[0.9998094,0.00002195838,0.000022230948,0.00008300862,0.000017493383,0.00004593389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017577337,0.000116023926,0.00015355044,0.00016117559,0.000008790759,0.000006168684,0.000089746434,0.0003331126,9.3436626e-7],"category_scores_gemma":[0.00023109833,0.00012232416,0.000024136923,0.00020908448,0.00002703833,0.0000029561375,0.00006031066,0.00031209923,6.9634446e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008187379,0.000009107971,0.0010587637,0.00014306523,0.000010394211,0.0000049305163,0.000030441126,0.0009454711,0.99602914,0.000027675664,0.000057320616,0.0016754945],"study_design_scores_gemma":[0.00044438944,0.000029844263,0.0014842434,0.00016256787,0.000004785374,0.000004920408,0.000050690014,0.0134769725,0.9829655,0.000006511081,0.0012553205,0.00011421222],"about_ca_topic_score_codex":0.0000486976,"about_ca_topic_score_gemma":0.00003080241,"teacher_disagreement_score":0.048214104,"about_ca_system_score_codex":0.000039129067,"about_ca_system_score_gemma":0.000045290457,"threshold_uncertainty_score":0.49882343},"labels":[],"label_agreement":null},{"id":"W4414394499","doi":"10.21203/rs.3.rs-7614961/v1","title":"Activation mechanism and molecular engineering of Staphylococcus aureus Cas9","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Core Research for Evolutional Science and Technology; Jichi Medical University; Japan Agency for Medical Research and Development","keywords":"Nuclease; Cas9; DNA; Gene; CRISPR; Mechanism (biology); Genome; Genome engineering","score_opus":0.016217757720688612,"score_gpt":0.36951083261628365,"score_spread":0.353293074895595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414394499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91968113,0.0031351252,0.07575551,0.00010786001,0.00012704374,0.0006440456,0.000107854576,0.000020133426,0.0004213085],"genre_scores_gemma":[0.99722224,0.00058066443,0.0016858061,0.000009640699,0.00010021412,0.00008400274,0.00013215982,0.00002406018,0.00016118112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986898,0.000065159395,0.00019616928,0.0004305683,0.00031680518,0.00030150262],"domain_scores_gemma":[0.9990392,0.000035115438,0.00003978937,0.00051921717,0.0002808756,0.000085835454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040730118,0.0001864663,0.00020291869,0.00025662026,0.00003872751,0.000029412791,0.00022251614,0.00035779667,0.0000065409026],"category_scores_gemma":[0.0002653584,0.00020553375,0.00008767171,0.00014136806,0.00003771717,0.0000015370089,0.0009196283,0.00045614215,5.316648e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022490733,0.000024196946,0.00008401248,0.0013621084,0.0000908712,0.0000046795667,0.00007250111,0.009254846,0.9868936,0.0011531399,0.00017406714,0.00086352124],"study_design_scores_gemma":[0.00019544023,0.00013187574,0.00065484014,0.00038918096,0.000011962891,8.059411e-7,0.000078201294,0.0024886788,0.99360234,0.00065185764,0.0016067504,0.00018804826],"about_ca_topic_score_codex":0.000075336415,"about_ca_topic_score_gemma":0.0000066163384,"teacher_disagreement_score":0.07754114,"about_ca_system_score_codex":0.000029620918,"about_ca_system_score_gemma":0.00016511513,"threshold_uncertainty_score":0.83814234},"labels":[],"label_agreement":null},{"id":"W4414397593","doi":"10.3389/fgeed.2025.1697828","title":"Editorial: Insights in genome editing in human health and disease 2023/2024","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Mental Health; U.S. Army Medical Research Acquisition Activity; National Institutes of Health","keywords":"Genome editing; Pseudogene; Genome; Human genome; Homologous recombination; Gene; Indel; Zinc finger nuclease","score_opus":0.0035252377901791913,"score_gpt":0.2707680832999367,"score_spread":0.26724284550975747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414397593","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0034215178,0.03132037,0.0012676005,0.000094221425,0.9626911,0.00056234666,0.0002449689,0.000022653421,0.00037516726],"genre_scores_gemma":[0.0039391653,0.0024860804,0.0009157294,0.00006387292,0.98891366,0.00012990544,0.0026082166,0.00009287516,0.00085049245],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962688,0.000158749,0.0009999707,0.0011885869,0.00049530057,0.00088857167],"domain_scores_gemma":[0.998695,0.00007403158,0.00026863438,0.000486843,0.000093636256,0.00038181248],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00081311376,0.0005730111,0.00081440975,0.00082101265,0.00013380307,0.00009673438,0.0004537194,0.0009448198,0.0000057068273],"category_scores_gemma":[0.0014572621,0.00070376176,0.00011609509,0.00044943395,0.00008883022,0.000014442376,0.0004495003,0.0013623319,0.0000010264474],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049992017,0.000052102736,0.0016513619,0.0008217905,0.000039577902,0.000037331203,0.0004442888,0.0011904825,0.0012462034,0.000003420792,0.9939562,0.0005072493],"study_design_scores_gemma":[0.0012193259,0.00011958793,0.0005748896,0.000638746,0.000018328388,4.2755096e-7,0.0007778406,0.0001396094,0.000040313855,0.00020286393,0.9956638,0.00060426595],"about_ca_topic_score_codex":0.00023325464,"about_ca_topic_score_gemma":0.000565204,"teacher_disagreement_score":0.028834289,"about_ca_system_score_codex":0.0003921062,"about_ca_system_score_gemma":0.0008824702,"threshold_uncertainty_score":0.99954134},"labels":[],"label_agreement":null},{"id":"W4414410029","doi":"10.1128/msphere.00453-25","title":"CRISPR adaptation in <i>Streptococcus thermophilus</i> benefits from phage environmental DNA","year":2025,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Hamilton Health Sciences","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Context (archaeology); Bacteria; DNA; Genome; Acquired immune system; Immune system; Adaptation (eye); Cas9","score_opus":0.004797674833868477,"score_gpt":0.24646866418302701,"score_spread":0.24167098934915854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414410029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98817736,0.004509836,0.003930335,0.000068644746,0.0001393637,0.00015260483,0.00004826729,0.000011953403,0.002961613],"genre_scores_gemma":[0.99845463,0.00018142565,0.00032660077,0.00017197404,0.000081202415,0.000028565146,0.00016625265,0.000013194422,0.0005761327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993897,0.000016355085,0.00013584718,0.000251693,0.000060079663,0.00014630253],"domain_scores_gemma":[0.999721,0.000007792652,0.000020191244,0.0002177623,0.000004407329,0.000028842775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000034048102,0.0001153367,0.000087910405,0.000016991073,0.000026351821,0.000012345666,0.00010808248,0.000101329046,0.000119105236],"category_scores_gemma":[0.000008789619,0.00012258875,0.000045650075,0.00005182556,0.000017868104,0.000002368416,0.0000615854,0.000062387226,0.000015766775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032803542,0.000066641805,0.011634515,0.000009407392,0.00003386648,0.0000043216282,0.0001166385,0.0068931575,0.9383555,0.000033613233,0.0011508615,0.041668683],"study_design_scores_gemma":[0.0011617776,0.000069728754,0.13255662,0.000044583277,0.000021402802,9.4269507e-7,0.0005445807,0.0014090153,0.838246,0.00016160368,0.025511071,0.000272673],"about_ca_topic_score_codex":0.000058120597,"about_ca_topic_score_gemma":0.00025048622,"teacher_disagreement_score":0.1209221,"about_ca_system_score_codex":0.000016599719,"about_ca_system_score_gemma":0.000016232432,"threshold_uncertainty_score":0.49990243},"labels":[],"label_agreement":null},{"id":"W4414516612","doi":"10.1016/j.xgen.2025.101011","title":"Repeats mimic pathogen-associated patterns across a vast evolutionary landscape","year":2025,"lang":"en","type":"article","venue":"Cell Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"H2020 Marie Skłodowska-Curie Actions; National Institute on Aging; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Canadian Institutes of Health Research; Mark Foundation For Cancer Research; Natural Sciences and Engineering Research Council of Canada; Edward P. Evans Foundation; National Institute of General Medical Sciences; National Cancer Institute; National Sleep Foundation; Fondation de l'Avenir pour la Recherche Médicale Appliquée; Pershing Square Sohn Cancer Research Alliance","keywords":"Mimicry; Mechanism (biology); Innate immune system; Transcription (linguistics); DNA; Transcription factor; Pattern recognition receptor","score_opus":0.004061720629675371,"score_gpt":0.2601489315061326,"score_spread":0.25608721087645725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414516612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98703206,0.0023342082,0.008097372,0.0000320497,0.00031435187,0.00008368183,0.00011843464,0.000019579813,0.001968244],"genre_scores_gemma":[0.99653393,0.00043843518,0.00037563647,0.00016656774,0.000110677975,0.000012786627,0.00036846922,0.000019174315,0.00197434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992756,0.00001622649,0.00014985313,0.00026237912,0.000047230496,0.00024869238],"domain_scores_gemma":[0.99958426,0.000007941125,0.000035514266,0.00028875173,0.000037752245,0.00004576859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008754364,0.00011676962,0.00009175359,0.000023863824,0.000082094884,0.000019461993,0.00014668926,0.00014331241,0.000017457789],"category_scores_gemma":[0.000021204703,0.0001357067,0.00008629092,0.000066322325,0.000017273158,0.0000011479656,0.00013916468,0.00007091898,0.000012614566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026667309,0.00006500691,0.02147383,0.000038547827,0.000057114044,0.0000062655245,0.00012628308,0.0022677053,0.97018236,0.000010007538,0.0044585164,0.0012876926],"study_design_scores_gemma":[0.0022388396,0.00022654602,0.13713157,0.000060821927,0.00009235684,0.000028922523,0.00090224936,0.0032499204,0.7530226,0.00011166455,0.1021104,0.0008241106],"about_ca_topic_score_codex":0.000008704,"about_ca_topic_score_gemma":0.000029353001,"teacher_disagreement_score":0.21715978,"about_ca_system_score_codex":0.000023104967,"about_ca_system_score_gemma":0.000060245766,"threshold_uncertainty_score":0.5533958},"labels":[],"label_agreement":null},{"id":"W4414527373","doi":"10.1101/2025.09.25.678665","title":"Sensitive, direct detection of non-coding off-target base editor unwinding and editing in primary cells","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wu Tsai Neurosciences Institute, Stanford University; National Institutes of Health; Canadian Institutes of Health Research; Bristol-Myers Squibb","keywords":"Base (topology); Knowledge base; Base pair; DNA; Epigenetics; Deep sequencing; Nucleotide","score_opus":0.0038729589530624286,"score_gpt":0.21605238924247397,"score_spread":0.21217943028941155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414527373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96963346,0.0014201312,0.024209931,0.000017149176,0.003888514,0.0004793703,0.0002576033,0.000049388625,0.00004446518],"genre_scores_gemma":[0.99278855,0.0005398699,0.0042925174,0.000038422215,0.0022320119,0.000046360383,0.0000015900766,0.000053846372,0.0000068031254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814343,0.00007360969,0.00045494645,0.0007756841,0.0001767582,0.0003755501],"domain_scores_gemma":[0.9989139,0.000047093123,0.00022626208,0.0005142046,0.00018783948,0.000110700224],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053448754,0.00038832545,0.00047435786,0.0002949095,0.00006998161,0.000044375996,0.00017561251,0.0005065953,0.0000016494545],"category_scores_gemma":[0.00016636601,0.00047596928,0.000110800465,0.00024527143,0.00006167521,0.000008781582,0.00049020816,0.000407292,8.9121625e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002886498,0.00003526643,0.0021209538,0.0007516682,0.00006923027,0.0000104322635,0.000010083605,0.0013324496,0.9955091,9.623828e-7,0.00011449599,0.000016497015],"study_design_scores_gemma":[0.00038608714,0.000045824523,0.017753592,0.0005776583,0.000049106216,2.0510097e-8,0.000007770801,0.0017653251,0.977911,1.3824811e-7,0.0011076404,0.00039584277],"about_ca_topic_score_codex":0.00003121717,"about_ca_topic_score_gemma":0.0000055666032,"teacher_disagreement_score":0.023155132,"about_ca_system_score_codex":0.00009628461,"about_ca_system_score_gemma":0.00021462393,"threshold_uncertainty_score":0.9997692},"labels":[],"label_agreement":null},{"id":"W4414532073","doi":"10.21203/rs.3.rs-7194258/v1","title":"Activating a patient-relevant mutation of a genetically defined heart disease in a humanized pig model","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Optech (Canada)","funders":"","keywords":"Somatic cell; Somatic cell nuclear transfer; Mutation; Transgene; Genetically modified organism; Humanized mouse; Cardiomyopathy; Animal model; Disease; Genetically engineered","score_opus":0.02836824762873488,"score_gpt":0.3960758196490974,"score_spread":0.3677075720203625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414532073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9765503,0.002168498,0.01945531,0.00020026074,0.000055067536,0.0010004113,0.0001713615,0.000014289299,0.00038450534],"genre_scores_gemma":[0.9941532,0.00018511093,0.004882661,0.000025220046,0.000050575352,0.0002671308,0.00025430112,0.000027016846,0.00015477097],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9979356,0.00019850032,0.00041178777,0.00057114806,0.0004683087,0.0004146362],"domain_scores_gemma":[0.9987495,0.0000753159,0.00006189775,0.00059200445,0.00038673574,0.00013457981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043153827,0.00020577807,0.00027410578,0.00030773337,0.000054541535,0.00003087773,0.00024413974,0.00024453286,0.000012597871],"category_scores_gemma":[0.0009473872,0.0002198081,0.00013953236,0.00021057512,0.00006999425,0.0000019368292,0.000888083,0.0005008784,0.0000018439167],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000638296,0.00043636412,0.0024185122,0.0032709886,0.00008498952,0.000023540606,0.0007536828,0.5044454,0.47750804,0.00024332467,0.0005342685,0.009642614],"study_design_scores_gemma":[0.0031806706,0.001080815,0.027404407,0.0041325227,0.000060927883,0.000003575825,0.000604191,0.70623416,0.24956006,0.0053709596,0.0011696733,0.001198044],"about_ca_topic_score_codex":0.000099480516,"about_ca_topic_score_gemma":0.00005615147,"teacher_disagreement_score":0.22794798,"about_ca_system_score_codex":0.00006191761,"about_ca_system_score_gemma":0.00070254237,"threshold_uncertainty_score":0.89635146},"labels":[],"label_agreement":null},{"id":"W4414560878","doi":"10.1016/b978-0-443-43920-9.00008-7","title":"CRISPR-edited plants for herbicide resistance: Methods and applications","year":2025,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Acetolactate synthase; CRISPR; Genome editing; Weed; Herbicide resistance; Crop","score_opus":0.010485455964422926,"score_gpt":0.3374651274048758,"score_spread":0.32697967144045287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414560878","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000070448696,0.017886806,0.06581922,0.000042633474,0.00020629934,0.0009906802,0.00023146102,0.000026871521,0.91478896],"genre_scores_gemma":[0.0001004361,0.0007804304,0.027572664,0.00020833066,0.00057415443,0.00032278054,0.00026240054,0.000054899818,0.9701239],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989874,0.00001320194,0.0002613239,0.00047360256,0.00007129301,0.00019322797],"domain_scores_gemma":[0.99926496,0.000048296133,0.00008059034,0.00045472875,0.00007350879,0.000077894794],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017589606,0.00027433562,0.00028241237,0.000070013695,0.000087614346,0.000021896501,0.00015709561,0.00029593942,0.000007800258],"category_scores_gemma":[0.000024289133,0.00028891096,0.00012638979,0.0000070488854,0.000061005507,6.7610006e-7,0.00010258067,0.00013876382,0.0000018018619],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040072213,0.0000036371237,0.0000011653983,0.00032924133,0.00015303776,9.276755e-7,0.000016569715,0.0000027448118,0.016200658,0.0021545647,0.003191108,0.9779063],"study_design_scores_gemma":[0.00024294191,0.000028667555,0.0000063305597,0.00012851697,0.00009482,0.0000037933828,0.0000053668673,0.000007182413,0.020130811,0.003212809,0.97585684,0.0002819429],"about_ca_topic_score_codex":1.7934279e-7,"about_ca_topic_score_gemma":0.000027187367,"teacher_disagreement_score":0.97762436,"about_ca_system_score_codex":0.00001291772,"about_ca_system_score_gemma":0.00006368286,"threshold_uncertainty_score":0.9999563},"labels":[],"label_agreement":null},{"id":"W4414566467","doi":"10.1002/cctc.202500809","title":"Essential Logic and Facts Behind the Expansion of the Genetic Code: A Critical Assessment","year":2025,"lang":"en","type":"article","venue":"ChemCatChem","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"University of Manitoba; Research Manitoba","keywords":"Genetic code; Amino acid; Translation (biology); Flexibility (engineering); Stop codon; Codon usage bias","score_opus":0.007167880173574357,"score_gpt":0.3284700813521019,"score_spread":0.32130220117852754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414566467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98366463,0.001579406,0.012254217,0.001379346,0.00018933437,0.00013938312,0.0000065760055,0.000005492224,0.0007816322],"genre_scores_gemma":[0.9983656,0.00010817786,0.0009429301,0.00020695326,0.000063509186,0.00001438511,0.0000048420916,0.000007227136,0.00028639392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942404,0.000021231142,0.0001365867,0.00019081605,0.00009106843,0.00013626224],"domain_scores_gemma":[0.9995305,0.000030370918,0.000024064733,0.0003389481,0.000047094516,0.000029002504],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008452773,0.000097977776,0.0000919189,0.000010859856,0.00007474605,0.000015676025,0.00018155636,0.00008622944,0.000008193197],"category_scores_gemma":[0.00008122854,0.0000611658,0.00005657281,0.00005375126,0.00015686419,0.0000010746203,0.00021288896,0.000089526395,4.1480814e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007395097,0.00002489807,0.0017747147,0.00005719433,0.000024583576,4.5549316e-7,0.00007769736,0.00004941917,0.995193,0.00023879725,0.00081002805,0.0017418021],"study_design_scores_gemma":[0.00020281471,0.000027361064,0.03202411,0.000022581433,0.0000386643,0.0000062820427,0.00014697082,0.00020933837,0.9647546,0.0003317774,0.0021613834,0.00007413819],"about_ca_topic_score_codex":0.0000068584995,"about_ca_topic_score_gemma":0.000009244383,"teacher_disagreement_score":0.03043844,"about_ca_system_score_codex":0.000006444978,"about_ca_system_score_gemma":0.00007284231,"threshold_uncertainty_score":0.24942692},"labels":[],"label_agreement":null},{"id":"W4414587150","doi":"10.1101/2025.09.28.678669","title":"Directed evolution of a compact TranC11a system for efficient genome editing","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Genome editing; Zinc finger nuclease; Genome; Transposable element; Human genome; Directed evolution; DNA Transposable Elements","score_opus":0.0066085729112240555,"score_gpt":0.23666296567439493,"score_spread":0.23005439276317088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414587150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8108779,0.0050707916,0.17986923,0.000022092554,0.001586708,0.0011135645,0.0012363279,0.00019885023,0.000024481507],"genre_scores_gemma":[0.9958263,0.00003845393,0.0032737881,0.000008287388,0.00066343154,0.00012219812,0.000003711262,0.000057217,0.0000066058965],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981823,0.00005343943,0.0005081929,0.0006828328,0.00017850843,0.00039473947],"domain_scores_gemma":[0.9984441,0.000024757232,0.00027098478,0.00076698017,0.00037614323,0.00011707906],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037510117,0.00037893356,0.00048310895,0.00017954737,0.000085862936,0.000033571854,0.0003441881,0.00044741368,0.000001909486],"category_scores_gemma":[0.00011928849,0.0004331767,0.00025801445,0.00021856182,0.000050794435,0.0000018728251,0.00016823607,0.00020679057,0.0000010404497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004670316,0.00005998213,0.00043301127,0.0019297198,0.00018409047,0.000001347567,0.0000052318946,0.020257736,0.97687143,0.00012459532,0.00008520962,9.512959e-7],"study_design_scores_gemma":[0.0006733325,0.000086499545,0.016683191,0.00064583565,0.0001755046,2.058349e-8,0.000010195258,0.009460543,0.9693405,1.8837227e-7,0.002444223,0.00047995645],"about_ca_topic_score_codex":0.000030761043,"about_ca_topic_score_gemma":0.0000018280574,"teacher_disagreement_score":0.18494835,"about_ca_system_score_codex":0.0001890846,"about_ca_system_score_gemma":0.00036704956,"threshold_uncertainty_score":0.999812},"labels":[],"label_agreement":null},{"id":"W4414660595","doi":"10.1038/s41598-025-21748-2","title":"Correction: Miniaturized scalable arrayed CRISPR screening in primary cells enables discovery at the single donor resolution","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; McGill University","funders":"","keywords":"CRISPR; Scalability; Primary cell; Resolution (logic); Primary (astronomy)","score_opus":0.006124842569879226,"score_gpt":0.24439760988020975,"score_spread":0.23827276731033054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414660595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96383613,0.0021792725,0.016254878,0.0001950234,0.01142022,0.00034077748,0.000003437586,0.000024398627,0.005745858],"genre_scores_gemma":[0.8985877,0.00003545557,0.0011390287,0.00009214677,0.00012625485,0.000034049823,0.00017083055,0.000014434175,0.099800095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856037,0.000039153365,0.00034219518,0.0005941147,0.00017937619,0.00028479876],"domain_scores_gemma":[0.99911255,0.00002416643,0.00010003701,0.000665545,0.00006011984,0.000037597583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074851455,0.00013100932,0.00013144236,0.00009681404,0.00028417193,0.00018982742,0.000117790914,0.000097915756,0.000015366888],"category_scores_gemma":[0.00011424297,0.00010722034,0.00008926604,0.00037117605,0.00013828886,0.000012033586,0.00019191137,0.00009347028,0.000002614054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042628624,0.000038044996,0.0009919784,0.000018601995,0.000012979282,0.000013937905,0.00003502357,0.0037072569,0.91509026,0.000001019229,0.079207234,0.0008410261],"study_design_scores_gemma":[0.00017328169,0.00001957285,0.0030890298,0.00005538542,0.000013329982,0.000031482283,0.00007747487,0.00023950297,0.85210925,0.000046376485,0.14402664,0.00011866482],"about_ca_topic_score_codex":0.000041000192,"about_ca_topic_score_gemma":0.00023291628,"teacher_disagreement_score":0.09405424,"about_ca_system_score_codex":0.00005544458,"about_ca_system_score_gemma":0.00010797181,"threshold_uncertainty_score":0.43723187},"labels":[],"label_agreement":null},{"id":"W4414691509","doi":"10.1186/s13765-025-01046-1","title":"Application of the OsRPS5 promoter for CRISPR/Cas9-mediated genome editing in rice","year":2025,"lang":"en","type":"article","venue":"Applied Biological Chemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"National Research Foundation of Korea; Rural Development Administration; Seoul National University; National Research Foundation","keywords":"Promoter; Genome; Genome editing; Transgene; Gene; Reporter gene","score_opus":0.006412060559036623,"score_gpt":0.2650859206607422,"score_spread":0.25867386010170557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414691509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9636603,0.00032213467,0.032063987,0.00018204797,0.000051058953,0.00054195797,0.0000360033,0.000016803939,0.003125714],"genre_scores_gemma":[0.9986632,0.00002130798,0.00055208313,0.00013991173,0.00013778513,0.0002291334,0.00016142447,0.0000072550138,0.00008791463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922246,0.000007471043,0.00023017444,0.00030049993,0.000048918162,0.0001904546],"domain_scores_gemma":[0.99957746,0.000033431694,0.00006463163,0.00026387355,0.00003580253,0.000024802357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014339421,0.00012199218,0.00013724585,0.000011462847,0.00003502616,0.0000052445134,0.00025106248,0.00023813754,0.0000045310967],"category_scores_gemma":[0.00011573018,0.000087744425,0.00007066419,0.00014692801,0.00007025262,6.5229335e-7,0.00013390878,0.00010039537,8.341098e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032738928,0.000039273044,0.0012256472,0.00009125085,0.000013301125,7.403145e-8,0.00000753021,0.00010706867,0.99748796,0.00005452367,0.00007028024,0.00087033556],"study_design_scores_gemma":[0.00039305154,0.000016879723,0.010316844,0.000008457706,0.000007788696,9.032529e-7,0.00004802237,0.00016000537,0.97983354,0.00021076054,0.008900082,0.00010368267],"about_ca_topic_score_codex":0.0000033628485,"about_ca_topic_score_gemma":0.0000016431702,"teacher_disagreement_score":0.035002895,"about_ca_system_score_codex":0.000013956798,"about_ca_system_score_gemma":0.000025647334,"threshold_uncertainty_score":0.3578114},"labels":[],"label_agreement":null},{"id":"W4414870992","doi":"10.1101/cshperspect.a041700","title":"Telomerase RNA Shapes the Evolutionary Diversity of Telomerase Ribonucleoproteins (RNPs)","year":2025,"lang":"en","type":"article","venue":"Cold Spring Harbor Perspectives in Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences","keywords":"Telomerase; Telomerase RNA component; Telomere; Ribonucleoprotein; RNA; Biogenesis; Non-coding RNA; Telomerase reverse transcriptase; RNA-dependent RNA polymerase","score_opus":0.007491442138485449,"score_gpt":0.2956691074959487,"score_spread":0.28817766535746325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414870992","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835853,0.012498398,0.0022976873,0.0003425082,0.00016030844,0.00026671359,0.000021567637,0.000017597986,0.0008099113],"genre_scores_gemma":[0.99805146,0.0010968297,0.00056859176,0.000077033525,0.000085006526,0.000024652236,0.000001732784,0.000009441891,0.00008524353],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99908006,0.000066482484,0.00018779626,0.00036759645,0.000057911522,0.00024014605],"domain_scores_gemma":[0.99947906,0.000044666078,0.00005158064,0.00031124346,0.00007994326,0.000033520777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018427143,0.00014804861,0.00017826089,0.00012965834,0.00014390732,0.000005874447,0.0003389116,0.00014076792,0.00001836273],"category_scores_gemma":[0.0001987903,0.00012957705,0.0000939071,0.0002250001,0.00027486266,0.0000034706975,0.0005473179,0.00015633635,0.000002090332],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010202359,0.00014123533,0.053042408,0.000032070424,0.00011723478,0.000003803298,0.00026858517,0.00041371418,0.9165167,0.028866386,0.00016210381,0.0003336919],"study_design_scores_gemma":[0.0010785181,0.00023819508,0.6460669,0.00006329863,0.000041039017,0.000001280001,0.0010026259,0.00047205013,0.33930627,0.00039843709,0.010979038,0.0003523455],"about_ca_topic_score_codex":0.00026606835,"about_ca_topic_score_gemma":0.00007569645,"teacher_disagreement_score":0.5930245,"about_ca_system_score_codex":0.000059364596,"about_ca_system_score_gemma":0.00006336484,"threshold_uncertainty_score":0.5283998},"labels":[],"label_agreement":null},{"id":"W4414987850","doi":"10.21203/rs.3.rs-7576931/v1","title":"The SMARCA5–DMRT1 Pioneer Complex Establishes Epigenetic Priming to Direct Male Germline Development","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Chromatin; Enhancer; Epigenetics; Transcription factor; Germline; Priming (agriculture); Promoter; ChIA-PET; SMARCA4","score_opus":0.05098018274192405,"score_gpt":0.4155838032776899,"score_spread":0.36460362053576584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414987850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8633155,0.0327818,0.0529483,0.0043537356,0.0021561936,0.006748302,0.0004420394,0.00019482992,0.037059296],"genre_scores_gemma":[0.9640993,0.00200748,0.008583213,0.00010592634,0.0006658784,0.00082332816,0.00066538254,0.00007441022,0.022975104],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99688375,0.00023660573,0.0004362021,0.00085280323,0.00069446943,0.000896143],"domain_scores_gemma":[0.9978034,0.00018744545,0.00005041816,0.0011575662,0.0005456315,0.0002555197],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014737739,0.0003457977,0.00029962356,0.00022983356,0.00052950514,0.0002542399,0.0009511172,0.00031304458,0.000059591286],"category_scores_gemma":[0.00068458094,0.00028979473,0.00015174133,0.00030767318,0.00010809203,0.0000017817475,0.0031175436,0.00065128406,0.000033032145],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064528565,0.0005856397,0.008669179,0.005716302,0.0013442603,0.00009009705,0.0030250712,0.07942846,0.39841637,0.00026222112,0.14995684,0.35186028],"study_design_scores_gemma":[0.00024433495,0.00015415819,0.020568043,0.00049205206,0.000018560277,0.0000055930527,0.00028283722,0.00059810997,0.17722903,0.000048746773,0.79982716,0.00053136115],"about_ca_topic_score_codex":0.00008814352,"about_ca_topic_score_gemma":0.00036549423,"teacher_disagreement_score":0.64987034,"about_ca_system_score_codex":0.00012725536,"about_ca_system_score_gemma":0.0007225575,"threshold_uncertainty_score":0.9999554},"labels":[],"label_agreement":null},{"id":"W4415141910","doi":"10.1038/d41586-025-03307-x","title":"Faulty mitochondria cause deadly diseases: fixing them is about to get a lot easier","year":2025,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"World Federation of Science Journalists","funders":"","keywords":"DNA; Mitochondrial DNA; Mitochondrion; Mechanism (biology)","score_opus":0.004855509879196266,"score_gpt":0.3073637904597224,"score_spread":0.30250828058052615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415141910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737455,0.00902505,0.011049139,0.001828348,0.0010449365,0.00040012883,0.00019826322,0.000055288594,0.00265334],"genre_scores_gemma":[0.9885626,0.00007638501,0.0015040614,0.0045850445,0.0003115033,0.000029319099,0.00007507955,0.000021385764,0.0048346287],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99916464,0.000013161214,0.00011860318,0.00035055535,0.00010991175,0.00024310128],"domain_scores_gemma":[0.999394,0.000009768061,0.000018083052,0.00039663975,0.0000712921,0.000110189474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000034124674,0.00016215073,0.00012164798,0.000042278243,0.000060314145,0.000036201654,0.00021497768,0.0006046097,0.000040574905],"category_scores_gemma":[0.0001107895,0.00015064797,0.00009828725,0.00015790656,0.000015070053,0.0000020244256,0.00012270242,0.00040890506,0.000021876544],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018490902,0.000105450876,0.017216634,0.00015851023,0.0003189009,0.000023397768,0.00033506015,0.00097130006,0.5832535,0.00033855715,0.3912004,0.005893367],"study_design_scores_gemma":[0.00060774054,0.00005673188,0.026855862,0.00009117092,0.000080989266,0.000008149708,0.0000767016,0.00014332276,0.29045182,0.000090002824,0.68117684,0.00036066998],"about_ca_topic_score_codex":0.000007766945,"about_ca_topic_score_gemma":0.000020882375,"teacher_disagreement_score":0.2928017,"about_ca_system_score_codex":0.000016354918,"about_ca_system_score_gemma":0.000056424265,"threshold_uncertainty_score":0.61432457},"labels":[],"label_agreement":null},{"id":"W4415222194","doi":"10.1093/nar/gkaf990","title":"Codon specific readthrough as a mechanism of BRCA2 restoration in acquired PARP inhibitor and chemotherapy resistance","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Center for Individualized Medicine, Mayo Clinic; Fondation pour la Recherche Médicale; Glenn Foundation for Medical Research; Mayo Foundation for Medical Education and Research; National Cancer Institute; National Institutes of Health","keywords":"BRCA2 Protein; Stop codon; Open reading frame; PARP inhibitor; Gene; Mutation; Gene knockdown; Nonsense mutation; Polymerase","score_opus":0.019550043540314217,"score_gpt":0.35423285097866647,"score_spread":0.33468280743835227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415222194","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895729,0.0023847271,0.0024785555,0.00069576973,0.00007993734,0.0002942163,0.000005430207,0.000008896127,0.004479565],"genre_scores_gemma":[0.99438554,0.002053363,0.0012308691,0.000052081137,0.000077762226,0.000022677137,0.000013909831,0.000016764967,0.0021470492],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891376,0.00008752573,0.00021062423,0.00032260892,0.0002230933,0.00024236202],"domain_scores_gemma":[0.99943966,0.000027495804,0.000025419215,0.00034496593,0.00012073634,0.000041730487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057316636,0.00009752983,0.00013971698,0.00014553843,0.000057848174,0.000024196816,0.00015310518,0.00016091099,0.000018558989],"category_scores_gemma":[0.00010961291,0.0001031385,0.000028522392,0.0003309621,0.00012440264,0.0000051950124,0.00010297029,0.00011313823,0.0000033327922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000320045,0.00004456899,0.0005912844,0.00007143059,0.000014158425,0.00000337535,0.00023025057,0.0000087900435,0.9874191,0.0045726816,0.0038713163,0.002852994],"study_design_scores_gemma":[0.001004543,0.00022227885,0.006290657,0.000115749375,0.0000022404106,0.0000017571156,0.00036431348,0.00009551115,0.92408,0.0025270786,0.06517231,0.00012355729],"about_ca_topic_score_codex":0.00003621584,"about_ca_topic_score_gemma":0.00010136443,"teacher_disagreement_score":0.0633391,"about_ca_system_score_codex":0.000035347435,"about_ca_system_score_gemma":0.00007625272,"threshold_uncertainty_score":0.42058662},"labels":[],"label_agreement":null},{"id":"W4415222207","doi":"10.1101/2025.10.14.682350","title":"FlashRNA: An Efficient Model for Regulatory Genomics","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Vector Institute; Ontario Genomics","funders":"","keywords":"Inference; Genomics; Computational model; Computational complexity theory; Matching (statistics); Predictive modelling; Downstream (manufacturing)","score_opus":0.010261645319987493,"score_gpt":0.2540342647976596,"score_spread":0.24377261947767212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415222207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7245474,0.0017820661,0.27123487,0.00003676754,0.00089817593,0.00077339116,0.00060457626,0.00011269413,0.000010064806],"genre_scores_gemma":[0.96654767,0.00020455397,0.031905875,0.00017262598,0.00066593435,0.0003125901,0.000005304053,0.000117545,0.000067899],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997677,0.000037568698,0.0004365904,0.0011352977,0.00018013064,0.0005334076],"domain_scores_gemma":[0.99756676,0.000012993701,0.00016704519,0.0016570755,0.00035505957,0.00024105188],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041240858,0.00052443275,0.00040466743,0.00015187086,0.00013716676,0.00009230525,0.00062016264,0.0007300694,0.0000029359837],"category_scores_gemma":[0.000094235795,0.0006276484,0.00024534995,0.00011017381,0.00006926974,0.0000033924405,0.00055945455,0.00030552692,0.0000037718132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004022563,0.00007801193,0.000092825845,0.00027720866,0.000105542975,0.0000013729627,0.000006868643,0.25292394,0.74575627,0.00023415308,0.00048020645,0.000003359484],"study_design_scores_gemma":[0.0005432158,0.000073298295,0.0018996828,0.00009992289,0.00012839053,1.0161839e-8,0.000002061959,0.30835715,0.6811101,0.0000027184133,0.0069913054,0.0007921503],"about_ca_topic_score_codex":0.000005324717,"about_ca_topic_score_gemma":0.000003367854,"teacher_disagreement_score":0.2420003,"about_ca_system_score_codex":0.00012480751,"about_ca_system_score_gemma":0.00079356675,"threshold_uncertainty_score":0.99961746},"labels":[],"label_agreement":null},{"id":"W4415260891","doi":"10.1016/j.cell.2025.09.013","title":"Exploring Latin America one cell at a time","year":2025,"lang":"en","type":"article","venue":"Cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Institut National Du Cancer; Royal Society; Chan Zuckerberg Initiative; Wellcome Trust","keywords":"Latin Americans; Emerging technologies; The Internet; Development studies; Genomics","score_opus":0.016503830514931463,"score_gpt":0.24713116240110952,"score_spread":0.23062733188617807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415260891","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92780775,0.0013327728,0.007298071,0.000093966664,0.00014685627,0.00009100137,0.000004939677,0.000024891215,0.06319974],"genre_scores_gemma":[0.9625509,0.0002708874,0.0018992915,0.00016696361,0.00009242205,0.000020965592,0.000039362938,0.000014920266,0.034944315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995073,0.000008773438,0.00009146519,0.00019040333,0.00004399789,0.00015803934],"domain_scores_gemma":[0.99969506,0.0000069305142,0.000016975275,0.00022614872,0.000015396114,0.00003949108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000027789121,0.000086352295,0.00008099294,0.000027438153,0.00004210861,0.000008022374,0.00009116437,0.000059131024,0.000069502195],"category_scores_gemma":[0.0000076908145,0.00009578914,0.00004796049,0.00007254143,0.000017657158,0.0000010528328,0.000122050136,0.000059816637,0.00014470398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000098360015,0.00002763844,0.00008379849,0.000030181476,0.0000074383997,9.0753707e-7,0.000034670444,0.00048957655,0.9946046,0.0000016859939,0.0034404513,0.0012692348],"study_design_scores_gemma":[0.00019351469,0.000038948805,0.0005954294,0.0000070596975,0.000010033606,2.5358113e-7,0.000019610334,0.00019368727,0.8661941,0.0000053014646,0.1326484,0.00009361894],"about_ca_topic_score_codex":0.0000053206945,"about_ca_topic_score_gemma":0.0000016806492,"teacher_disagreement_score":0.12920794,"about_ca_system_score_codex":0.000011025556,"about_ca_system_score_gemma":0.000019371962,"threshold_uncertainty_score":0.39061677},"labels":[],"label_agreement":null},{"id":"W4415278771","doi":"10.3390/ijms262010107","title":"Surrogate Biomarkers in Gene Therapy for Orphan Diseases: Validation, Application, and Regulatory Aspects","year":2025,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Kazan Federal University; Ministry of Science and Higher Education of the Russian Federation","keywords":"Biomarker; Context (archaeology); Clinical trial; Surrogate endpoint; Biomarker discovery; Disease","score_opus":0.011505427959049427,"score_gpt":0.36063453912866034,"score_spread":0.34912911116961093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415278771","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031200435,0.9758155,0.02030052,0.00007083699,0.00034056013,0.00028126832,0.00003184463,0.000002236148,0.00003720449],"genre_scores_gemma":[0.012844244,0.985411,0.0014236097,0.00005086816,0.00015217085,0.000032634227,0.0000584176,0.000011143179,0.000015934549],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989133,0.000051804025,0.00041555837,0.00025456026,0.00025297224,0.000111844376],"domain_scores_gemma":[0.99928284,0.0000456432,0.00028286566,0.00011849572,0.00021827372,0.00005189793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043334533,0.00015186873,0.00029484692,0.00031700305,0.000032046453,0.00006127249,0.00050959067,0.00009073729,0.0000016522681],"category_scores_gemma":[0.00011985293,0.0001275986,0.00019645807,0.0001669054,0.00009318351,0.000007775689,0.000064278946,0.000054540138,2.1593584e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055285727,0.00009801064,0.00020517893,0.0007096996,0.0007922755,0.00002302757,0.000026908381,0.00073868333,0.010162502,0.0005427505,0.00027821455,0.98636746],"study_design_scores_gemma":[0.0021274162,0.00051740615,0.00036285567,0.00386449,0.00033575567,0.00031841293,0.00006158313,0.00013618935,0.041848272,0.0019320578,0.94773597,0.00075957685],"about_ca_topic_score_codex":0.0000027153299,"about_ca_topic_score_gemma":0.0000020154562,"teacher_disagreement_score":0.98560786,"about_ca_system_score_codex":0.000027047096,"about_ca_system_score_gemma":0.00042416836,"threshold_uncertainty_score":0.520332},"labels":[],"label_agreement":null},{"id":"W4415356690","doi":"10.1007/s40615-025-02702-4","title":"Sickle Cell Disease and Gene Therapy Among African Americans: A Dilemma and Challenge","year":2025,"lang":"en","type":"review","venue":"Journal of Racial and Ethnic Health Disparities","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Dilemma; Disease; Genetic enhancement; Acute chest syndrome; Epidemiology; African american; Genetic disorder; Heart disease","score_opus":0.03786158707140438,"score_gpt":0.3844685343957371,"score_spread":0.3466069473243327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415356690","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0042381035,0.99465823,0.0002625044,0.00033041355,0.00014821,0.00024407703,0.00006410309,0.0000036038382,0.000050740062],"genre_scores_gemma":[0.0065210843,0.9924998,0.00012625344,0.00017156656,0.00043818267,0.000019544725,0.000019453979,0.000021090598,0.00018297002],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99875855,0.00011943274,0.00050518446,0.00023425944,0.000117205615,0.00026536646],"domain_scores_gemma":[0.99907684,0.000060937266,0.0003169563,0.00013259807,0.00004833401,0.00036430414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028976516,0.000267374,0.00087380584,0.00010271553,0.00010246158,0.000035765945,0.00010049159,0.00014309332,0.0000023433465],"category_scores_gemma":[0.00005141956,0.00021079344,0.00015181402,0.000074075535,0.000168782,0.0000068855306,0.000088996436,0.00027059944,8.63871e-8],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056089528,0.00005013863,0.00007817584,0.0126976995,0.000105275336,0.000011254013,0.00029389182,0.0000021792773,0.000009491622,0.000015655185,0.00046238358,0.98621774],"study_design_scores_gemma":[0.0005158177,0.00067460665,0.0018963602,0.0032847389,0.00021641408,0.000042347216,0.00019689256,0.0000048826582,0.000010999463,0.0000677176,0.9927363,0.00035292993],"about_ca_topic_score_codex":0.00006231543,"about_ca_topic_score_gemma":0.000044998487,"teacher_disagreement_score":0.9922739,"about_ca_system_score_codex":0.00001476009,"about_ca_system_score_gemma":0.00040596764,"threshold_uncertainty_score":0.8595907},"labels":[],"label_agreement":null},{"id":"W4415364085","doi":"10.3389/fgeed.2025.1711767","title":"Editorial: Genome editing for climate change adaptation in agriculture: innovations, applications, and regulatory considerations","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Climate change; Adaptation (eye); Genome editing; Food security; Agriculture; Flooding (psychology); Agricultural productivity; Global warming; Transformative learning","score_opus":0.0070190968052204926,"score_gpt":0.26171452247989896,"score_spread":0.25469542567467846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415364085","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021267816,0.009940207,0.051727645,0.00012545704,0.9350926,0.001774209,0.00097411935,0.00003856113,0.00011451948],"genre_scores_gemma":[0.002023923,0.0017218847,0.017742604,0.000047560476,0.9693843,0.0020773453,0.0068660825,0.000056800927,0.00007949073],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99774337,0.000053096363,0.0007206978,0.00073456543,0.00027300007,0.00047524323],"domain_scores_gemma":[0.99882555,0.00013191796,0.00029737345,0.000306649,0.00037655476,0.00006194241],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007759853,0.00035571397,0.00041891207,0.0004067864,0.00021196979,0.00009401847,0.00017339544,0.00095899217,0.0000014316236],"category_scores_gemma":[0.00091100857,0.0004264867,0.00007399245,0.00033179708,0.0000571306,0.00002032974,0.00014471966,0.00049154845,4.4453944e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001978082,0.000030546427,0.0002660154,0.000573053,0.00004826034,0.0000010260217,0.00028659022,0.0011140038,0.004267823,0.000090700414,0.9918728,0.0014293904],"study_design_scores_gemma":[0.0007984079,0.000048989295,0.00038329166,0.00015425043,0.00004484285,9.459787e-7,0.0007649071,0.0003024186,0.00022095883,0.00028839483,0.9965734,0.0004191999],"about_ca_topic_score_codex":0.000024263616,"about_ca_topic_score_gemma":0.00011442219,"teacher_disagreement_score":0.034291703,"about_ca_system_score_codex":0.00015180824,"about_ca_system_score_gemma":0.00019336549,"threshold_uncertainty_score":0.9998187},"labels":[],"label_agreement":null},{"id":"W4415397430","doi":"10.1021/acsbiomedchemau.5c00174","title":"Manipulation of 7-Finger Zinc Finger Nuclease Increases the Efficiency of Genome Editing in Human Cells","year":2025,"lang":"en","type":"article","venue":"ACS Bio & Med Chem Au","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"Co-creation place formation support program; Foundation of Kinoshita Memorial Enterprise","keywords":"Zinc finger nuclease; Genome editing; Transcription activator-like effector nuclease; Zinc finger; Genome; Effector","score_opus":0.0070394267222787296,"score_gpt":0.27202335061606137,"score_spread":0.2649839238937826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415397430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973756,0.00055790896,0.0010092591,0.00005342141,0.00008406514,0.0001099116,0.000006370669,0.0000051238994,0.00079834217],"genre_scores_gemma":[0.9995257,0.000030142466,0.00010430426,0.00004239889,0.0001166937,0.000006398829,0.000033245135,0.0000096786935,0.0001314166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993163,0.000019469693,0.00025372402,0.00016834716,0.000084881394,0.00015732952],"domain_scores_gemma":[0.99957395,0.000022420167,0.00008025785,0.00025630265,0.00004439972,0.000022666653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018923564,0.0000972736,0.00012530161,0.00005793256,0.000040365514,0.000005246319,0.0001672223,0.000083268664,0.0000100778825],"category_scores_gemma":[0.00007834347,0.00008355124,0.000053446867,0.00014346033,0.00006077408,0.0000019528225,0.00009713346,0.00005822869,7.0139964e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000087125045,0.000056503064,0.0023407936,0.00006649649,0.000016142727,5.6760035e-7,0.0001303921,0.0009502764,0.9959961,0.000048886755,0.00008135631,0.0003037381],"study_design_scores_gemma":[0.00025069507,0.000037885453,0.01108646,0.00004183627,0.000020242576,5.755493e-7,0.000122051344,0.00015962904,0.98752576,0.000034624467,0.0006450411,0.00007517869],"about_ca_topic_score_codex":0.00017195569,"about_ca_topic_score_gemma":0.00006892087,"teacher_disagreement_score":0.008745667,"about_ca_system_score_codex":0.00001609461,"about_ca_system_score_gemma":0.000038271006,"threshold_uncertainty_score":0.34071207},"labels":[],"label_agreement":null},{"id":"W4415513543","doi":"10.5376/tgg.2025.16.0008","title":"CRISPR/Cas9-Mediated Editing of &lt;i&gt;TaGW2&lt;/i&gt; to Enhance Grain Size in Wheat","year":2025,"lang":"","type":"article","venue":"Triticeae Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Grain yield; Mutant; Crop; Wheat grain; Genome editing; Gene; Plant breeding; Crop yield","score_opus":0.004683808801042254,"score_gpt":0.28156654999857766,"score_spread":0.2768827411975354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415513543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90854543,0.07378231,0.011787687,0.0011741093,0.0013169331,0.0010597322,0.0003501976,0.000018413604,0.001965179],"genre_scores_gemma":[0.9656743,0.025249407,0.006525531,0.0006327016,0.00058192585,0.00005403547,0.000081560145,0.000092601425,0.0011079845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957289,0.0001460586,0.0014808798,0.0012293799,0.00028741854,0.001127347],"domain_scores_gemma":[0.99781036,0.00027098053,0.00021822716,0.0009345269,0.00034396275,0.0004219107],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007777614,0.00072119216,0.00092795194,0.00036254132,0.00016868858,0.00011054724,0.0005816203,0.000690745,0.00003122922],"category_scores_gemma":[0.0007571469,0.00091017206,0.0002336363,0.00070764293,0.00026538028,0.00000852856,0.00065794465,0.00035300813,0.00001021542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018582078,0.00022835612,0.0006084134,0.00064507395,0.00017408772,0.000016191332,0.0005944509,0.0027624194,0.97802216,0.00023796882,0.0009880873,0.015536982],"study_design_scores_gemma":[0.0028557181,0.0009601738,0.009195393,0.0005603788,0.00032706882,0.000021319016,0.0005302134,0.0041515636,0.7599901,0.00041027632,0.2196552,0.0013426192],"about_ca_topic_score_codex":0.000020632313,"about_ca_topic_score_gemma":0.0004851239,"teacher_disagreement_score":0.21866712,"about_ca_system_score_codex":0.000106059575,"about_ca_system_score_gemma":0.00043343782,"threshold_uncertainty_score":0.9993349},"labels":[],"label_agreement":null},{"id":"W4415524957","doi":"10.1371/journal.pcbi.1013606","title":"Similarity-based transfer learning with deep learning networks for accurate CRISPR-Cas9 off-target prediction","year":2025,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mila - Quebec Artificial Intelligence Institute; Université du Québec à Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Transfer of learning; Deep learning; Convolutional neural network; Artificial neural network; Source code; Metric (unit); Similarity (geometry); Multilayer perceptron; Field (mathematics)","score_opus":0.008433297848496543,"score_gpt":0.28867529766647587,"score_spread":0.2802419998179793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415524957","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.099633746,0.00073187303,0.89881796,0.00020118638,0.00011557853,0.000264724,0.0000162814,0.00005115209,0.00016749244],"genre_scores_gemma":[0.9852116,0.000036691472,0.0122441575,0.0003013182,0.0001515512,0.000092537586,0.0018494193,0.000021797627,0.000090896545],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99902856,0.000081488324,0.00020995173,0.00036278987,0.000060474616,0.0002567295],"domain_scores_gemma":[0.9995199,0.00013755204,0.00003395052,0.000088642126,0.0001741712,0.000045773904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013006049,0.00016910564,0.00016963459,0.000078702724,0.00018311439,0.00002003529,0.00009927309,0.00019082305,0.000011771468],"category_scores_gemma":[0.00008307729,0.00016102724,0.000076515564,0.000114883194,0.000058768004,0.0000035441508,0.000024821262,0.00020109782,0.0000010724164],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022875618,0.000043534892,0.010227257,0.000039326565,0.00014547224,6.0121323e-7,0.000020016456,0.971735,0.015023486,0.00039516113,0.000066970984,0.0020744312],"study_design_scores_gemma":[0.001271027,0.0007100706,0.0033454977,0.000026524222,0.000058251477,0.0000033269778,0.000031910527,0.96039534,0.015494122,0.0002668526,0.018199757,0.00019729577],"about_ca_topic_score_codex":0.0000016286743,"about_ca_topic_score_gemma":0.000006498015,"teacher_disagreement_score":0.8865738,"about_ca_system_score_codex":0.000014935821,"about_ca_system_score_gemma":0.000073102485,"threshold_uncertainty_score":0.65665007},"labels":[],"label_agreement":null},{"id":"W4415620365","doi":"10.1101/2025.10.24.684378","title":"A buffer-tuning strategy to profile domain-specific activity of chimeric I-TevI/CRISPR gene editors <i>in vitro</i>","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"MaRS; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nuclease; Cleavage (geology); Gene; Fusion gene; DNA; Fusion protein","score_opus":0.008007182207157928,"score_gpt":0.2469739556648612,"score_spread":0.23896677345770326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415620365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9289869,0.0056895236,0.057184573,0.000113773924,0.0047611347,0.002142475,0.0009688292,0.00009019351,0.000062615276],"genre_scores_gemma":[0.9769666,0.0019709172,0.017272107,0.00007682256,0.0030066054,0.00048372475,0.0000046667387,0.0001914099,0.000027149292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9934805,0.00033986286,0.0014342312,0.0025978545,0.00064443593,0.0015031355],"domain_scores_gemma":[0.995352,0.0000763296,0.00063414854,0.0026506942,0.00065059256,0.00063620484],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.000982871,0.0014551237,0.0016157734,0.0007261548,0.0001990251,0.0001638817,0.0013063313,0.0013960648,0.00004800852],"category_scores_gemma":[0.000121991914,0.0017920899,0.0005292099,0.0015600887,0.00022194255,0.00002499562,0.0013736015,0.0012288218,0.000025771265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000525736,0.0004873559,0.00053418917,0.0009506811,0.00033128881,0.000037654834,0.000027636122,0.0030422541,0.9933613,0.00004084579,0.0005721971,0.00008888504],"study_design_scores_gemma":[0.0011127517,0.00038691715,0.01042243,0.0005891797,0.00011061113,7.494396e-8,0.000017325508,0.00030384734,0.95535934,5.880781e-7,0.030196428,0.0015005143],"about_ca_topic_score_codex":0.00011353736,"about_ca_topic_score_gemma":0.000005722178,"teacher_disagreement_score":0.047979712,"about_ca_system_score_codex":0.00033116998,"about_ca_system_score_gemma":0.0013378755,"threshold_uncertainty_score":0.99990034},"labels":[],"label_agreement":null},{"id":"W4415652593","doi":"10.9734/acri/2025/v25i101589","title":"Harnessing CRISPR Genome Editing for Sustainable Agriculture, Livestock and Food Security","year":2025,"lang":"en","type":"article","venue":"Archives of Current Research International","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centennial College","funders":"","keywords":"Food security; CRISPR; Genome editing; Sustainability; Livestock; Agriculture; Transformative learning; Population","score_opus":0.020273417512879786,"score_gpt":0.38535705054447345,"score_spread":0.36508363303159364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415652593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7197718,0.015935088,0.24534425,0.00066216866,0.0006295555,0.0009911237,0.00013044028,0.000019423596,0.016516166],"genre_scores_gemma":[0.9974908,0.00033978652,0.00081921485,0.000007150866,0.00034263474,0.000058176898,0.00015075477,0.00000609754,0.0007853613],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992015,0.000033710694,0.00014604734,0.0002217758,0.00015295796,0.00024402478],"domain_scores_gemma":[0.9995025,0.00008780235,0.000030786057,0.0001032652,0.00022690865,0.00004874439],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002367898,0.000076484896,0.00007966669,0.00015639275,0.00010446016,0.00004551497,0.00021336901,0.000030903317,0.0000028436395],"category_scores_gemma":[0.0003352767,0.000071537994,0.000056343735,0.00006833908,0.00011079908,0.00000698553,0.00031079605,0.00012834638,1.7198327e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004021128,0.0005108052,0.00989138,0.0025906528,0.00054885366,0.0000025671097,0.0013391937,0.00087766815,0.75167286,0.17132305,0.010678479,0.050162397],"study_design_scores_gemma":[0.0018645787,0.0007833643,0.0227961,0.0004137964,0.000024643168,0.000008203744,0.0019469098,0.0037360853,0.34347397,0.04782742,0.5767914,0.00033351817],"about_ca_topic_score_codex":0.000006158533,"about_ca_topic_score_gemma":0.000006755753,"teacher_disagreement_score":0.56611294,"about_ca_system_score_codex":0.000009394961,"about_ca_system_score_gemma":0.00006533154,"threshold_uncertainty_score":0.2917235},"labels":[],"label_agreement":null},{"id":"W4415656346","doi":"10.1038/s41588-025-02368-y","title":"Cell-type- and locus-specific epigenetic editing of memory expression","year":2025,"lang":"en","type":"article","venue":"Nature Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Epigenetics; Epigenesis; Engram; Epigenetic regulation of neurogenesis; Regulator; Master regulator; Regulation of gene expression","score_opus":0.003453597764858766,"score_gpt":0.26723735004757154,"score_spread":0.2637837522827128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415656346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8883008,0.09958719,0.008412528,0.000048549908,0.0008110212,0.00015645676,0.0000075158437,0.0000121206995,0.0026638287],"genre_scores_gemma":[0.99032944,0.0037258803,0.0050365455,0.00009580181,0.00029423178,0.000004079179,0.00002847903,0.000020123472,0.00046542822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991229,0.000023288132,0.00021531989,0.00031890077,0.00012111267,0.00019844076],"domain_scores_gemma":[0.9993583,0.000020471174,0.00005541094,0.00036600733,0.0001427194,0.000057118385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010331617,0.00015993662,0.00015154511,0.000072793926,0.00005055733,0.000013125843,0.00016637368,0.00038477744,0.000009911789],"category_scores_gemma":[0.000060982013,0.00015971865,0.000044421464,0.0001741103,0.000061299565,0.0000011992422,0.00016944163,0.00021252352,0.0000011323415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023551233,0.000025145719,0.0022226581,0.00009944971,0.000015126485,0.0000012554234,0.00004261385,0.001257021,0.9842399,0.000014541658,0.006306884,0.0057518594],"study_design_scores_gemma":[0.00033680178,0.0000875133,0.0030718732,0.000043643366,0.00001774467,0.000002463858,0.000096062955,0.00008715525,0.9544852,0.00004947145,0.04158541,0.00013669826],"about_ca_topic_score_codex":8.1986036e-7,"about_ca_topic_score_gemma":0.0000017244491,"teacher_disagreement_score":0.10202864,"about_ca_system_score_codex":0.000005852329,"about_ca_system_score_gemma":0.000042628144,"threshold_uncertainty_score":0.6513137},"labels":[],"label_agreement":null},{"id":"W4415758224","doi":"10.1021/acssynbio.5c00843","title":"PHYCUT: Scalable Multiplex CRISPR/Cas9 Editing for Genome Engineering in the Diatom <i>Phaeodactylum tricornutum</i>","year":2025,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Synthetic biology; Genome engineering; Bioproduction; Genome editing; Glycosylation; Genome; Multiplex; Mycoplasma genitalium; Metabolic engineering","score_opus":0.007109945902991799,"score_gpt":0.29649040549583566,"score_spread":0.28938045959284386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415758224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84851813,0.004403517,0.14294083,0.0010881085,0.00090535963,0.0009617681,0.000066226516,0.00005292504,0.0010631141],"genre_scores_gemma":[0.99721265,0.00013939675,0.0012067559,0.00048557643,0.0003944592,0.00025223373,0.00009012986,0.000026715537,0.00019206508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859494,0.000060935563,0.00032103388,0.00044762998,0.000056436027,0.0005190114],"domain_scores_gemma":[0.9992122,0.00019711451,0.000053228083,0.0004450909,0.00005024504,0.000042119762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046541667,0.00023184833,0.0002513486,0.00012443046,0.00008911515,0.000025731824,0.00043003552,0.00025722297,0.0000068730324],"category_scores_gemma":[0.0004353329,0.00019165249,0.000106038715,0.00022275752,0.000067271394,0.0000034776247,0.00012799767,0.00016762839,0.0000045612796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005415261,0.00008938096,0.002324464,0.00010775925,0.00007592457,0.00000305515,0.00015465466,0.00229987,0.9874079,0.00075862807,0.0010020701,0.0057221223],"study_design_scores_gemma":[0.0033720494,0.00060394115,0.008520876,0.00009473979,0.000119135686,0.00006024218,0.00044408377,0.007944794,0.56642467,0.00063700596,0.41093734,0.0008411273],"about_ca_topic_score_codex":0.000030570558,"about_ca_topic_score_gemma":0.000029682471,"teacher_disagreement_score":0.42098325,"about_ca_system_score_codex":0.000021386271,"about_ca_system_score_gemma":0.000042569627,"threshold_uncertainty_score":0.78153616},"labels":[],"label_agreement":null},{"id":"W4415790496","doi":"10.1038/s41467-025-65182-4","title":"Unveiling the cut-and-repair cycle of designer nucleases in human stem and T cells via CLEAR-time dPCR","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"European Commission; AstraZeneca; University College London; Wellcome Trust; Wellcome; European Federation of Pharmaceutical Industries and Associations","keywords":"Genome editing; DNA; Digital polymerase chain reaction; DNA repair; Nuclease; CRISPR; Human genome; Mutation","score_opus":0.006202759564511129,"score_gpt":0.2977717713487883,"score_spread":0.2915690117842772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415790496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9749072,0.022278603,0.000528713,0.0005112204,0.000029242723,0.00017246162,0.000007555966,0.00001659863,0.0015483691],"genre_scores_gemma":[0.99769145,0.00065460923,0.0012922063,0.000115978895,0.000009223394,0.000007675618,0.000011450692,0.000006854054,0.00021052086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996185,0.000055275443,0.00012007214,0.00010363224,0.00003140595,0.000071164475],"domain_scores_gemma":[0.99926054,0.000056057124,0.000024299597,0.0006108404,0.000031552394,0.000016726224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012440779,0.00006229097,0.00007539941,0.00003395648,0.00009894884,0.000008493455,0.00024100237,0.00012020258,0.0000025081386],"category_scores_gemma":[0.000019408013,0.000052809613,0.000030094958,0.00009255268,0.00009298779,0.0000018264078,0.00024564887,0.00018355291,5.6938075e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010296108,0.000052562864,0.001964087,0.00002840034,0.000041571566,1.4674742e-7,0.00013003411,0.00032676564,0.9935894,0.0011011658,0.0009492815,0.0018062997],"study_design_scores_gemma":[0.00094046385,0.00016486786,0.046977263,0.00015034048,0.0001163974,0.0000071056315,0.0006219223,0.014903309,0.87082464,0.00044279065,0.06447674,0.0003741385],"about_ca_topic_score_codex":0.000018418668,"about_ca_topic_score_gemma":0.00012700951,"teacher_disagreement_score":0.12276473,"about_ca_system_score_codex":0.0000045001993,"about_ca_system_score_gemma":0.000013341832,"threshold_uncertainty_score":0.21535136},"labels":[],"label_agreement":null},{"id":"W4415794162","doi":"10.1161/circ.152.suppl_3.4364195","title":"Abstract 4364195: A transformative LDL cholesterol–lowering <i>in vivo</i> CRISPR gene editing medicine that functionally upregulates LDLR in mice and non-human primates","year":2025,"lang":"en","type":"article","venue":"Circulation","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"LDL receptor; Genome editing; Downregulation and upregulation; CRISPR; Familial hypercholesterolemia; Untranslated region; PCSK9; Cas9; Gene","score_opus":0.007069927089927009,"score_gpt":0.2847467637653683,"score_spread":0.2776768366754413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415794162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815902,0.0007838257,0.015813619,0.00018135752,0.00014799484,0.000212207,0.000004993049,0.000012489664,0.0012532946],"genre_scores_gemma":[0.99944943,0.00007572007,0.00011012876,0.000095719806,0.00012707069,0.000022972536,0.0000812982,0.0000127209205,0.000024912955],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991923,0.000011321451,0.00027011338,0.00025733892,0.000090545116,0.00017836649],"domain_scores_gemma":[0.9997595,0.000018165783,0.000049398477,0.000109041146,0.000031561707,0.00003235086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019806062,0.00014471004,0.000151651,0.0001310162,0.000056601184,0.000020567404,0.000062097504,0.00011174523,0.000008563773],"category_scores_gemma":[0.00002124044,0.00015228144,0.000030648465,0.000113999,0.000039479477,0.000017667146,0.000024924104,0.00009445184,4.85746e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015650441,0.000018010727,0.066293456,0.0001350939,0.000016740252,0.0000011660704,0.0003366173,0.007012729,0.9250524,0.000015665331,0.0000455514,0.0010569051],"study_design_scores_gemma":[0.0008266663,0.000018916324,0.6859178,0.00017880434,0.000012138242,0.000004173552,0.0002010334,0.0014489262,0.31105384,0.000067085726,0.00015327042,0.00011733851],"about_ca_topic_score_codex":0.00006467403,"about_ca_topic_score_gemma":0.00014304796,"teacher_disagreement_score":0.6196244,"about_ca_system_score_codex":0.000029428662,"about_ca_system_score_gemma":0.000015966529,"threshold_uncertainty_score":0.62098575},"labels":[],"label_agreement":null},{"id":"W4415826719","doi":"10.1016/j.talanta.2025.129072","title":"A reverse transcription-free CRISPR/Cas12a biosensor for ultrasensitive detection of SARS-CoV-2 variants","year":2025,"lang":"en","type":"article","venue":"Talanta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Dongguan Science and Technology Bureau; Guangdong Science and Technology Department","keywords":"Biosensor; Detection limit; DNA; Loop-mediated isothermal amplification; RNA; Mutant; Trans-activating crRNA; Fluorescence; Nucleic acid","score_opus":0.012504171390110634,"score_gpt":0.30083052210746924,"score_spread":0.2883263507173586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415826719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92014825,0.00023896429,0.078067586,0.000102887745,0.0002993003,0.0002807461,0.00018025577,0.000015759235,0.00066627015],"genre_scores_gemma":[0.99879164,0.00008213028,0.0004963171,0.00014089144,0.000073095885,0.000016624852,0.000052556003,0.000012176279,0.00033456468],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994078,0.000016151973,0.0001623178,0.00021605936,0.000051200368,0.00014643269],"domain_scores_gemma":[0.9995776,0.000016209491,0.000034526634,0.00027989454,0.00007375824,0.000018005716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008212031,0.00010753626,0.00012810108,0.000059128633,0.0000379023,0.0000065844265,0.000094446434,0.00010656731,0.0000014061302],"category_scores_gemma":[0.00009560834,0.00011245858,0.00010128441,0.00008618079,0.00003274384,0.0000022609056,0.000021866483,0.00004162103,0.0000014302988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016003329,0.00003095875,0.000034907906,0.0000708831,0.00006440934,0.0000012960518,0.00005021568,0.000022250513,0.9966373,0.000058022906,0.0018313742,0.0010383856],"study_design_scores_gemma":[0.0008605858,0.00013653167,0.0009963803,0.000029715933,0.000055914745,0.000012288251,0.00009136339,0.00018661306,0.99173594,0.00007494836,0.00570912,0.000110577515],"about_ca_topic_score_codex":0.000048831895,"about_ca_topic_score_gemma":0.00013125053,"teacher_disagreement_score":0.07864341,"about_ca_system_score_codex":0.000008318143,"about_ca_system_score_gemma":0.00002442681,"threshold_uncertainty_score":0.4585928},"labels":[],"label_agreement":null},{"id":"W4415900447","doi":"10.1016/j.jgg.2025.10.007","title":"Dual-target CRISPR-Cas12 diagnostics based on asymmetrically chemical-modified DNA probe","year":2025,"lang":"en","type":"article","venue":"Journal of genetics and genomics/Journal of Genetics and Genomics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; China Postdoctoral Science Foundation; National Natural Science Foundation of China; Canadian Anesthesiologists' Society","keywords":"Nucleic acid; Nucleic acid detection; Loop-mediated isothermal amplification; DNA; Nucleic acid quantitation; Genotyping; Molecular beacon","score_opus":0.006968832976051445,"score_gpt":0.2655626390729586,"score_spread":0.25859380609690713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415900447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90164816,0.037332468,0.058776133,0.0007327754,0.0008909771,0.00028173224,0.000051769897,0.00000399249,0.00028200066],"genre_scores_gemma":[0.9201714,0.034030274,0.043677013,0.0009382088,0.0009901435,0.0000029269884,0.000012578032,0.00007704785,0.00010045196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969823,0.00008260615,0.001605691,0.00041685667,0.00039369366,0.00051886064],"domain_scores_gemma":[0.99712104,0.0001777701,0.0009586043,0.00045753768,0.0008067956,0.000478234],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008772033,0.0005083239,0.00080609764,0.0005556165,0.0001490274,0.00017216132,0.00049604464,0.00041052286,0.0000064054875],"category_scores_gemma":[0.0003100684,0.00047544664,0.00035872258,0.00026186908,0.0001984731,0.000009756834,0.00025512965,0.000549086,9.2793914e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001177573,0.0005849719,0.0045111715,0.00026416735,0.00082941435,0.000126193,0.00029523444,0.051566847,0.90612346,0.00028232316,0.0040818984,0.03015673],"study_design_scores_gemma":[0.0082033975,0.0059627076,0.0163626,0.00034022698,0.0010464902,0.0010594316,0.000357101,0.015973896,0.77944785,0.0036993055,0.1660837,0.0014633213],"about_ca_topic_score_codex":0.0000021784626,"about_ca_topic_score_gemma":0.0000036769088,"teacher_disagreement_score":0.16200179,"about_ca_system_score_codex":0.00009658464,"about_ca_system_score_gemma":0.0006270936,"threshold_uncertainty_score":0.99976975},"labels":[],"label_agreement":null},{"id":"W4415928236","doi":"10.1101/2025.11.04.686611","title":"Large-scale discovery of neural enhancers for cis-regulation therapies","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Enhancer; Gene; Multiplex; CRISPR; Genetic enhancement; Gene targeting","score_opus":0.00678493764448056,"score_gpt":0.2528169648940894,"score_spread":0.24603202724960882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415928236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78157353,0.0032505945,0.21294089,0.00006149217,0.0008960784,0.0005648043,0.00066261156,0.00004207841,0.000007906795],"genre_scores_gemma":[0.99409306,0.00031376464,0.004859493,0.0000622033,0.00039140997,0.00017232336,0.000005024078,0.000049530234,0.000053209595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985715,0.000033395903,0.00035162183,0.00058896816,0.00013677723,0.00031774823],"domain_scores_gemma":[0.9987312,0.00002079952,0.00018545135,0.0007625051,0.00024222634,0.000057849735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022107402,0.00032173563,0.00033944298,0.0001040922,0.00006314069,0.000052935306,0.00030249153,0.0003829064,0.000005336621],"category_scores_gemma":[0.00006262934,0.00034874596,0.00022758922,0.00012249275,0.00005529741,0.0000076624665,0.00026574175,0.0001553971,6.663719e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007327528,0.00005059007,0.0008670062,0.0004541794,0.00014750364,3.15662e-7,0.000015712185,0.0021501381,0.9958432,0.00010494724,0.00028841934,0.0000047634417],"study_design_scores_gemma":[0.00045278273,0.0000830747,0.013557485,0.00013401087,0.00007791093,3.1408414e-9,0.000009134849,0.0017777071,0.978694,0.0000030511446,0.0048483233,0.0003624785],"about_ca_topic_score_codex":0.000007593759,"about_ca_topic_score_gemma":0.000006245327,"teacher_disagreement_score":0.21251948,"about_ca_system_score_codex":0.00003418211,"about_ca_system_score_gemma":0.00020721696,"threshold_uncertainty_score":0.99989647},"labels":[],"label_agreement":null},{"id":"W4415954927","doi":"10.1038/s41564-025-02180-8","title":"An updated evolutionary classification of CRISPR–Cas systems including rare variants","year":2025,"lang":"en","type":"review","venue":"Nature Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; U.S. National Library of Medicine; National Institute of General Medical Sciences; H. Lundbeck A/S; Novo Nordisk Fonden; Julius-Maximilians-Universität Würzburg; National Research University Higher School of Economics; NHLBI Division of Intramural Research; Novo Nordisk; European Regional Development Fund; Generalitat Valenciana; Technische Universiteit Delft; European Commission; California Institute for Quantitative Biosciences; Broad Institute; Innovative Genomics Institute; Agencia Estatal de Investigación; Villum Fonden; Gladstone Institutes; Deutsche Forschungsgemeinschaft; UK Research and Innovation; University of Washington; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Genome; Gene; Cleave; DNA; Replication (statistics); Phylogenetics; Genomics","score_opus":0.015034171820072235,"score_gpt":0.36070410292694016,"score_spread":0.34566993110686794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415954927","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000076968136,0.9923515,0.004725694,0.000009618863,0.0012312724,0.00053716596,0.00074808305,0.000025948872,0.00029375157],"genre_scores_gemma":[0.015814751,0.96520674,0.00049587374,0.00003175775,0.00037834176,0.000051149997,0.017618487,0.000045478027,0.00035744422],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981572,0.00026241312,0.0005861959,0.0006603023,0.00004743827,0.00028642238],"domain_scores_gemma":[0.99873185,0.00003362626,0.00029432564,0.000698256,0.00018654909,0.00005539078],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00019644103,0.00038772615,0.0009600856,0.00023674662,0.00006647889,0.000012344511,0.0005095343,0.0024148936,0.000015282916],"category_scores_gemma":[0.00007440153,0.00034903787,0.00025025496,0.00027138894,0.00006941694,0.000003020823,0.00017519682,0.00058385875,0.0000057436782],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076295706,0.00025543576,0.0000548964,0.020915022,0.001247881,0.00001642478,0.000037858816,0.00018243039,0.80377203,0.0014289479,0.050947398,0.121065386],"study_design_scores_gemma":[0.00017754642,0.00010744678,0.00004121437,0.0014797226,0.00030446384,0.00018166262,0.000018203005,0.000025140258,0.0028861954,0.0000050262233,0.9944274,0.00034600304],"about_ca_topic_score_codex":0.000008066991,"about_ca_topic_score_gemma":0.0000055831465,"teacher_disagreement_score":0.94347996,"about_ca_system_score_codex":0.00006010746,"about_ca_system_score_gemma":0.0003339864,"threshold_uncertainty_score":0.99989617},"labels":[],"label_agreement":null},{"id":"W4416102959","doi":"10.1038/s41587-025-02896-2","title":"A parts list of promoters and gRNA scaffolds for mammalian genome engineering and molecular recording","year":2025,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Human Genome Research Institute; Natural Sciences and Engineering Research Council of Canada; U.S. Department of Health and Human Services; National Institutes of Health; Washington Research Foundation; University of Washington; Damon Runyon Cancer Research Foundation","keywords":"Synthetic biology; Guide RNA; Genome engineering; Multiplex; Genome editing; Genome; Saturated mutagenesis; Mutagenesis; CRISPR; Complementary sequences","score_opus":0.0021467441332127294,"score_gpt":0.2490215944860873,"score_spread":0.24687485035287457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416102959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95548266,0.01101112,0.0316433,0.0013132233,0.00016439905,0.0002878114,0.000016672866,0.000032554628,0.000048259986],"genre_scores_gemma":[0.992271,0.00027962297,0.0072164815,0.00008102763,0.000028360837,0.000021423595,0.000016510003,0.0000146206075,0.00007092214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936813,0.000004940553,0.00012945352,0.0002892213,0.000030743795,0.00017748355],"domain_scores_gemma":[0.9996971,0.000009053114,0.00003085342,0.00020459622,0.000029157583,0.00002926395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088118904,0.00012433133,0.00015258923,0.00013439993,0.000026836116,0.000008526243,0.00009999669,0.00067614194,6.755094e-7],"category_scores_gemma":[0.000080200734,0.00013051374,0.00003832603,0.00010729533,0.000061045546,0.0000015980958,0.00011603685,0.00011576753,4.4190795e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020099185,0.0000073021297,0.00016334098,0.00013023474,0.000047802056,0.00000178216,0.0000070381307,0.000036765858,0.9921215,0.0017695643,0.000069205715,0.005625368],"study_design_scores_gemma":[0.0003592696,0.00015801087,0.00042047375,0.00003296513,0.000026622609,0.000018607683,0.00001635969,0.00046346025,0.9622845,0.00014447841,0.035943788,0.00013144097],"about_ca_topic_score_codex":0.0000036361987,"about_ca_topic_score_gemma":0.000005635359,"teacher_disagreement_score":0.036788374,"about_ca_system_score_codex":0.0000060993675,"about_ca_system_score_gemma":0.000014008928,"threshold_uncertainty_score":0.5322196},"labels":[],"label_agreement":null},{"id":"W4416118211","doi":"10.1016/j.ymthe.2025.11.010","title":"CD33 epitope editing unlocks UM171-expanded cord blood grafts for AML immunotherapy","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; University of Alberta; Institute for Research in Immunology and Cancer","funders":"Stem Cell Network","keywords":"CD33; Myeloid leukemia; Myeloid; Immunotherapy; Haematopoiesis; Epitope; Cord blood; Antigen","score_opus":0.006278468461614668,"score_gpt":0.30429686279496015,"score_spread":0.2980183943333455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416118211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72816426,0.014528008,0.2549081,0.00037709306,0.00060640986,0.00063733227,0.000019801677,0.00005556156,0.0007034244],"genre_scores_gemma":[0.9914242,0.0017418993,0.0035335363,0.0015311545,0.00031999865,0.00019688491,0.0001391723,0.000066482266,0.001046673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987041,0.000041481995,0.00027400954,0.00045864124,0.000121625,0.00040015767],"domain_scores_gemma":[0.9992144,0.000019273015,0.000061566716,0.00053625926,0.00010729369,0.000061174585],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001835879,0.00027466408,0.0002335591,0.000083834224,0.00012678544,0.0000514675,0.00030874833,0.00019626116,0.000018564207],"category_scores_gemma":[0.000038416416,0.00027761183,0.00024909005,0.00015220852,0.000047221878,0.0000029793407,0.000052281517,0.00010576773,0.0000029661514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021541926,0.00008463042,0.00032557553,0.000018943028,0.00031071037,0.0000047187204,0.000032583357,0.0002506678,0.9393098,0.0001877126,0.00086202234,0.058397263],"study_design_scores_gemma":[0.0025350244,0.00044335602,0.00038126376,0.000024646239,0.000025026036,0.000007691757,0.000033352513,0.00011345986,0.88001484,0.00039534073,0.11576098,0.00026500388],"about_ca_topic_score_codex":0.000013940004,"about_ca_topic_score_gemma":0.000007037526,"teacher_disagreement_score":0.26325995,"about_ca_system_score_codex":0.000011021893,"about_ca_system_score_gemma":0.000059085556,"threshold_uncertainty_score":0.99996763},"labels":[],"label_agreement":null},{"id":"W4416121707","doi":"10.1186/s12985-025-02990-6","title":"Discarded diversity: novel megaphages, auxiliary metabolic genes, and virally encoded CRISPR-Cas systems in landfills","year":2025,"lang":"en","type":"article","venue":"Virology Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canada Research Chairs; Joint Genome Institute; University of Waterloo; U.S. Department of Energy","keywords":"Key (lock); Virus; Contamination; Genome","score_opus":0.0064693215240316316,"score_gpt":0.2700541268051245,"score_spread":0.26358480528109285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416121707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92420554,0.039248753,0.03516434,0.00031123604,0.0006023086,0.00012576935,0.0000160941,0.000009207128,0.00031676868],"genre_scores_gemma":[0.99466366,0.0040907837,0.00043298016,0.00025376957,0.00017811859,0.0000067150727,0.000013159675,0.000011269764,0.00034952743],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99902785,0.00007650831,0.00025318933,0.00026118822,0.000089501285,0.0002917556],"domain_scores_gemma":[0.99961436,0.000017815297,0.000059134505,0.00018263806,0.000038192713,0.00008787302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033897447,0.00016339694,0.00025706174,0.00017859245,0.0001614398,0.000036805603,0.0001990239,0.000205676,0.0000074383365],"category_scores_gemma":[0.000041088548,0.00015005325,0.00007091714,0.00010353678,0.00006560242,0.0000064059054,0.00034419826,0.0002348745,0.0000015153123],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001396436,0.00007785609,0.070766725,0.000034896962,0.00026341912,0.000063041836,0.00013801553,0.002957713,0.9206607,0.00028150278,0.0011686797,0.003447808],"study_design_scores_gemma":[0.010134356,0.00058212434,0.6364999,0.00011685414,0.00047481954,0.002106168,0.00068128516,0.005128423,0.21887328,0.00050696195,0.1238264,0.0010694574],"about_ca_topic_score_codex":0.00007972961,"about_ca_topic_score_gemma":0.000094508076,"teacher_disagreement_score":0.7017874,"about_ca_system_score_codex":0.000013381207,"about_ca_system_score_gemma":0.00005559573,"threshold_uncertainty_score":0.61189944},"labels":[],"label_agreement":null},{"id":"W4416167091","doi":"10.1111/bioe.70051","title":"Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People","year":2025,"lang":"en","type":"article","venue":"Bioethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre","funders":"Canadian Institutes of Health Research","keywords":"Narrative; Identity (music); Narrative identity; Bioethics; Social identity theory; Affect (linguistics); Genome editing; Social identity approach","score_opus":0.050662970659818944,"score_gpt":0.3895599709626776,"score_spread":0.33889700030285863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416167091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986724,0.0019390741,0.00840687,0.001652426,0.00011155214,0.00019670214,0.000013412298,0.0000055545797,0.00095041434],"genre_scores_gemma":[0.9975028,0.0014860352,0.00032433198,0.00019237553,0.000040865707,0.0000180898,0.000011103936,0.0000058885066,0.00041847664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948776,0.000041874344,0.00012198663,0.0001692861,0.00007842815,0.00010069534],"domain_scores_gemma":[0.9996332,0.00004647108,0.000027518268,0.00021892042,0.00004854698,0.000025321026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012993626,0.00009972365,0.00011421481,0.000015965525,0.00007583834,0.000014531283,0.00008430708,0.00012390295,0.000005759272],"category_scores_gemma":[0.000060949416,0.00006891427,0.00006776111,0.000071825154,0.00014712526,0.000001110308,0.0000498014,0.00005726709,0.0000010076385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017900673,0.00043092656,0.0037571976,0.0001607537,0.00048820517,0.0000016105325,0.009766195,0.0011187831,0.90378237,0.07003082,0.0019708513,0.00831329],"study_design_scores_gemma":[0.0011879625,0.0014467087,0.029313112,0.000046202134,0.0001140459,0.000004043129,0.0038237465,0.0012850601,0.9473796,0.0017482509,0.013324042,0.0003272656],"about_ca_topic_score_codex":0.000043104705,"about_ca_topic_score_gemma":0.00047041543,"teacher_disagreement_score":0.068282574,"about_ca_system_score_codex":0.000008740239,"about_ca_system_score_gemma":0.000055487133,"threshold_uncertainty_score":0.28102422},"labels":[],"label_agreement":null},{"id":"W4416257247","doi":"10.1371/journal.pone.0335863","title":"Improved CRISPR/Cas9 off-target prediction with DNABERT and epigenetic features","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; University of Tokyo","keywords":"Interpretability; Leverage (statistics); Epigenetics; Deep learning; Epigenome; Genomics; Genome; Benchmark (surveying)","score_opus":0.0055633272442177,"score_gpt":0.22959177188442634,"score_spread":0.22402844464020863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416257247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9767645,0.008833391,0.01218629,0.0003576824,0.000059450784,0.00031041974,0.000023308408,0.000035246845,0.0014296988],"genre_scores_gemma":[0.9906262,0.0007443249,0.005433498,0.00015438654,0.00011386809,0.000042905845,0.000054929405,0.000017605682,0.0028122673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993688,0.000012635333,0.00010232565,0.00026714936,0.00007939573,0.00016969162],"domain_scores_gemma":[0.99963737,0.000007017574,0.000020378011,0.0002279618,0.000053941098,0.000053315856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000049311784,0.00012367667,0.00012345948,0.00004093913,0.000054043147,0.00002323085,0.00006888351,0.0001007247,0.0000071704617],"category_scores_gemma":[0.00003514674,0.00011171935,0.00002246809,0.00006805936,0.000036467536,0.000002183547,0.000055506345,0.00007847146,7.721446e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007731388,0.00014995412,0.0067023262,0.00010720391,0.0002464901,0.0000010642434,0.00003148702,0.00007068688,0.9902545,0.000014484128,0.00067883544,0.0016656455],"study_design_scores_gemma":[0.0005685837,0.00034422104,0.026106564,0.000069357164,0.000115325995,0.000003754592,0.00003214307,0.0008588613,0.9695057,0.000036213754,0.0022197382,0.00013951478],"about_ca_topic_score_codex":0.000011105453,"about_ca_topic_score_gemma":0.000030573476,"teacher_disagreement_score":0.020748787,"about_ca_system_score_codex":0.0000067613846,"about_ca_system_score_gemma":0.000030355508,"threshold_uncertainty_score":0.4555783},"labels":[],"label_agreement":null},{"id":"W4416334295","doi":"10.1038/s41576-025-00907-1","title":"Harnessing artificial intelligence to advance CRISPR-based genome editing technologies","year":2025,"lang":"en","type":"article","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; Vector Institute; Toronto Rehabilitation Institute; University of Toronto","funders":"","keywords":"Genome editing; Genome; Selection (genetic algorithm); Key (lock); Synthetic biology; Field (mathematics); Applications of artificial intelligence","score_opus":0.012451304499577945,"score_gpt":0.35599610300310075,"score_spread":0.3435447985035228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416334295","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009846099,0.22943026,0.75731057,0.0014229422,0.0007840958,0.00063749996,0.000012562945,0.00008765512,0.00046829274],"genre_scores_gemma":[0.8608339,0.011245955,0.12522025,0.0016852056,0.000575364,0.000092829476,0.000061437044,0.000048784717,0.00023628511],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985161,0.000041614923,0.00043767798,0.00051961484,0.00012827563,0.00035676008],"domain_scores_gemma":[0.9990612,0.000019439723,0.000084519816,0.0006473746,0.0001281431,0.000059322483],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030348933,0.0002637576,0.00029362415,0.00013664611,0.000107821754,0.000049603073,0.00044057966,0.00040906988,0.000007001304],"category_scores_gemma":[0.0006320805,0.00025304046,0.00013088356,0.0004927993,0.000053983196,0.0000024455844,0.00019369781,0.0003725833,0.000021046664],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014716211,0.000034024542,0.00016458373,0.00024676017,0.000018626624,0.0000025356928,0.000017134795,0.007620599,0.4326968,0.00046145517,0.0009509151,0.55777186],"study_design_scores_gemma":[0.000026460662,0.000043449225,0.00007760567,0.0001490656,0.000022936123,0.0000016275251,0.00006316363,0.0004245108,0.524641,0.00031464387,0.47403046,0.00020511546],"about_ca_topic_score_codex":5.485489e-7,"about_ca_topic_score_gemma":0.000018822695,"teacher_disagreement_score":0.8509878,"about_ca_system_score_codex":0.000027130658,"about_ca_system_score_gemma":0.00006434312,"threshold_uncertainty_score":0.9999922},"labels":[],"label_agreement":null},{"id":"W4416345602","doi":"10.1016/j.lfs.2025.124087","title":"CRISPR's impact on cancer: From fundamental models to clinical solutions","year":2025,"lang":"en","type":"article","venue":"Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Canadian Institute for Military and Veteran Health Research","keywords":"CRISPR; Genome engineering; Genome editing; Chimeric antigen receptor; Genome; Cancer; Synthetic biology; Prime (order theory)","score_opus":0.058796937365484664,"score_gpt":0.44928888073459833,"score_spread":0.39049194336911364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416345602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97052866,0.0018129075,0.023368558,0.0010834819,0.0007764545,0.00009980108,0.0000775477,0.000013383407,0.0022391826],"genre_scores_gemma":[0.9970752,0.0002579813,0.00079696876,0.0013457565,0.0002571614,0.0000141703995,0.000008017833,0.0000034183352,0.00024131479],"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","domain_scores_codex":[0.9992064,0.000021552883,0.00014596002,0.00031064136,0.00010361776,0.00021179947],"domain_scores_gemma":[0.9996569,0.00002423715,0.000017263208,0.00016534318,0.00001853645,0.0001176945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018551547,0.00008638741,0.00009535827,0.000043084572,0.00013779444,0.000029269642,0.00022419934,0.000045994566,0.000030088739],"category_scores_gemma":[0.000046654935,0.00006865008,0.00008408721,0.00017283724,0.0000924604,0.0000031435802,0.000107487176,0.000052920364,0.0000104382825],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019796712,0.00028938032,0.10051096,0.000011528313,0.00025504574,0.0000019372517,0.00025604948,0.58498955,0.14255963,0.0014643639,0.14189795,0.027565617],"study_design_scores_gemma":[0.0027311961,0.0038301304,0.48297146,0.00034239914,0.00017955166,0.0000032595528,0.0022039348,0.121359155,0.2557267,0.0062370887,0.12251846,0.0018966639],"about_ca_topic_score_codex":0.0004964268,"about_ca_topic_score_gemma":0.00015527583,"teacher_disagreement_score":0.4636304,"about_ca_system_score_codex":0.000012182345,"about_ca_system_score_gemma":0.0001758373,"threshold_uncertainty_score":0.2799469},"labels":[],"label_agreement":null},{"id":"W4416366282","doi":"10.1021/acssynbio.5c00537","title":"Effective Strategies for Translating CRISPR-dCas Systems to Diverse Microbes","year":2025,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Troubleshooting; Function (biology); Metagenomics; Synthetic biology; Range (aeronautics)","score_opus":0.008197246238464065,"score_gpt":0.3326908026795897,"score_spread":0.32449355644112565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416366282","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.469666,0.002899637,0.5234287,0.00035774155,0.0008700579,0.0009944382,0.00007919745,0.000036679965,0.0016675533],"genre_scores_gemma":[0.99767023,0.00003382411,0.0014374838,0.00016428778,0.00013238238,0.00024330389,0.000038263548,0.000016665985,0.00026356423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902016,0.00005619702,0.0001922006,0.0003922058,0.000027748547,0.00031148174],"domain_scores_gemma":[0.9995108,0.00007728222,0.000029543104,0.00026079555,0.000071640316,0.000049893424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017028538,0.00017741174,0.00021322699,0.000078851546,0.00009368863,0.000029892417,0.00018499486,0.00020527728,0.0000035057947],"category_scores_gemma":[0.00009837106,0.00016514151,0.0000879725,0.00008697289,0.00006360218,0.0000021289907,0.000074026844,0.00006255633,0.0000062864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006506429,0.000021490188,0.00025612072,0.00009879339,0.00010125364,5.841973e-7,0.00015110183,0.0015138473,0.9832519,0.0030312138,0.0008032392,0.010705365],"study_design_scores_gemma":[0.00089599576,0.000752683,0.00047596058,0.0001128394,0.00010859579,0.000017357754,0.002018478,0.00037866752,0.89647985,0.0010345227,0.097270966,0.0004540844],"about_ca_topic_score_codex":0.000060264127,"about_ca_topic_score_gemma":0.000048200054,"teacher_disagreement_score":0.5280042,"about_ca_system_score_codex":0.0000131032775,"about_ca_system_score_gemma":0.000050433904,"threshold_uncertainty_score":0.6734275},"labels":[],"label_agreement":null},{"id":"W4416470123","doi":"10.21956/gatesopenres.16671.r36085","title":"Referee report. For: Taking stock: Is gene drive research delivering on its principles? [version 1; peer review: 1 approved, 3 approved with reservations]","year":2024,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Action (physics); The Internet; Control (management)","score_opus":0.12743794500529593,"score_gpt":0.44449789723632777,"score_spread":0.31705995223103184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416470123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.847904,0.031593222,0.03185787,0.059283704,0.00037883464,0.0074146343,0.002150623,0.00019700541,0.019220103],"genre_scores_gemma":[0.7149246,0.0066159014,0.014236019,0.0001985013,0.00087512645,0.000970923,0.0057347147,0.00024629643,0.25619796],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955888,0.00018170095,0.00044035132,0.0008931289,0.00217994,0.00071610964],"domain_scores_gemma":[0.9933502,0.00015643456,0.000091099275,0.0009314447,0.0052966597,0.00017417154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0056957807,0.0002260994,0.00027308738,0.000300816,0.00030297475,0.00009187161,0.0005538819,0.0002080036,0.000053894044],"category_scores_gemma":[0.0035061166,0.0001904443,0.0001438682,0.0006435014,0.00015290522,0.000016840671,0.0004702471,0.00065019715,0.00003135532],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003484899,0.000091647904,0.00017663844,0.002416302,0.00019012776,0.000059020364,0.00027160393,0.00059576915,0.7109166,0.00019727527,0.28032994,0.004406586],"study_design_scores_gemma":[0.00026347526,0.00062647247,0.00043744763,0.0013985615,0.000013578583,0.00002696156,0.00012262861,0.0017196534,0.36656082,0.000015098549,0.62863564,0.00017968519],"about_ca_topic_score_codex":0.00013715643,"about_ca_topic_score_gemma":0.00010307538,"teacher_disagreement_score":0.34830567,"about_ca_system_score_codex":0.00013500897,"about_ca_system_score_gemma":0.00035515564,"threshold_uncertainty_score":0.7766093},"labels":[],"label_agreement":null},{"id":"W4416482738","doi":"10.21956/gatesopenres.16671.r36080","title":"Referee report. For: Taking stock: Is gene drive research delivering on its principles? [version 1; peer review: 1 approved with reservations]","year":2024,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Action (physics); The Internet; Control (management); Government (linguistics)","score_opus":0.13308861794167684,"score_gpt":0.45239144456230207,"score_spread":0.31930282662062526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416482738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8747747,0.02845442,0.01908079,0.054550353,0.0002972261,0.005243375,0.0016851267,0.0001458257,0.015768213],"genre_scores_gemma":[0.7685875,0.006114928,0.00929925,0.00014843272,0.00066754257,0.00060154265,0.004247966,0.00017501296,0.21015778],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99605584,0.00016077746,0.0003812737,0.0007556557,0.0020206766,0.0006257789],"domain_scores_gemma":[0.9937973,0.00016496507,0.00007339554,0.00080198084,0.0050114947,0.00015086577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0053374646,0.00018844294,0.00023149657,0.0002742376,0.0002738112,0.0000758582,0.00047190307,0.00017444459,0.000062170846],"category_scores_gemma":[0.0032344083,0.00015811983,0.00012235518,0.0005789122,0.00012820729,0.0000135151095,0.00039838837,0.0005567038,0.000030606992],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002721116,0.00007016685,0.00019679444,0.0019526139,0.00016130599,0.00006238504,0.0002408602,0.00053370517,0.68891776,0.00021201368,0.30422315,0.003157161],"study_design_scores_gemma":[0.00020373799,0.0005648058,0.00049097417,0.0014052559,0.000012474925,0.000023505925,0.00008847659,0.0011872165,0.3775814,0.0000132705545,0.6182839,0.00014494848],"about_ca_topic_score_codex":0.00009168964,"about_ca_topic_score_gemma":0.00008614364,"teacher_disagreement_score":0.3140608,"about_ca_system_score_codex":0.000118762415,"about_ca_system_score_gemma":0.00031910627,"threshold_uncertainty_score":0.644794},"labels":[],"label_agreement":null},{"id":"W4416489299","doi":"10.21956/gatesopenres.16671.r36087","title":"Referee report. For: Taking stock: Is gene drive research delivering on its principles? [version 1; peer review: 1 approved, 2 approved with reservations]","year":2024,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Action (physics); The Internet; Control (management)","score_opus":0.1259139585642942,"score_gpt":0.44437196091768555,"score_spread":0.3184580023533914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416489299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8468166,0.032135323,0.031431004,0.059769113,0.00038090008,0.007467247,0.0021573545,0.00019885272,0.019643605],"genre_scores_gemma":[0.71345836,0.0067859,0.014345938,0.00020183194,0.00089146604,0.0009862514,0.0059291953,0.0002499921,0.25715104],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99558985,0.00018179366,0.00044035108,0.0008929064,0.0021791419,0.00071594195],"domain_scores_gemma":[0.99339783,0.00015577454,0.00009119151,0.0009311516,0.005249868,0.00017416537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0056729303,0.00022606734,0.00027311855,0.00030073893,0.0003030138,0.00009187882,0.00055391673,0.00020801896,0.00005416035],"category_scores_gemma":[0.0034728497,0.0001904336,0.00014385323,0.00064329244,0.00015289469,0.000016839436,0.00047047017,0.0006501846,0.000030811843],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034810152,0.00009240948,0.00017332827,0.002420348,0.0001918145,0.000060222275,0.0002740013,0.0006028133,0.7034915,0.00020273613,0.28765404,0.004488666],"study_design_scores_gemma":[0.00026288573,0.00062943366,0.00043539115,0.0013918342,0.00001368577,0.000027310381,0.0001225115,0.0017140819,0.3630092,0.000015211615,0.63219845,0.00017998405],"about_ca_topic_score_codex":0.0001370061,"about_ca_topic_score_gemma":0.00010299801,"teacher_disagreement_score":0.3445444,"about_ca_system_score_codex":0.00013460616,"about_ca_system_score_gemma":0.00035372298,"threshold_uncertainty_score":0.7765657},"labels":[],"label_agreement":null},{"id":"W4416571445","doi":"10.1093/nar/gkaf1293","title":"CRISPR/Cas12a2 enables ultra-sensitive amplification-free RNA detection","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Korea Evaluation Institute of Industrial Technology; Korea Environmental Industry and Technology Institute; National Research Foundation of Korea; Korea Health Industry Development Institute; Ministry of Health and Welfare; Ministry of Science and ICT, South Korea; Ministry of Environment; Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries; Ministry of Agriculture, Food and Rural Affairs; Korea Research Institute of Bioscience and Biotechnology; Ministry of Trade, Industry and Energy; Ministry of Environment - Saskatchewan; National Research Foundation","keywords":"CRISPR; RNA; Trans-activating crRNA; Guide RNA; Cas9; Complementarity (molecular biology)","score_opus":0.020604599034485315,"score_gpt":0.360625925873777,"score_spread":0.3400213268392917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416571445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8215969,0.001205167,0.13514772,0.0013375625,0.00038292204,0.00056152075,0.00003262111,0.00007232397,0.039663266],"genre_scores_gemma":[0.9952258,0.00032756646,0.00063409307,0.000105583786,0.00018660843,0.000047750164,0.000029976194,0.000023671513,0.0034189583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858254,0.00011031209,0.0001790947,0.00042614882,0.00028329706,0.0004186241],"domain_scores_gemma":[0.99876195,0.000060111954,0.00002012542,0.00072551257,0.0003446633,0.00008763292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005558218,0.00013085965,0.00011494806,0.00019283322,0.00024979882,0.00006588178,0.00035788756,0.00018846139,0.000028993789],"category_scores_gemma":[0.00065993785,0.00013475474,0.00007083808,0.00040676558,0.00014150853,0.000004685785,0.00017205045,0.00027810317,0.00004568559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063112835,0.00003237757,0.00020593836,0.000030119087,0.000041038278,0.0000025653994,0.00006531278,0.000098849705,0.975283,0.0003128642,0.007857092,0.01600773],"study_design_scores_gemma":[0.00034183307,0.00011576098,0.004670272,0.000019553463,0.00000721382,0.000005625634,0.00041057268,0.0002020857,0.92842275,0.00040137026,0.06527772,0.00012522093],"about_ca_topic_score_codex":0.000075656535,"about_ca_topic_score_gemma":0.00007707528,"teacher_disagreement_score":0.1736289,"about_ca_system_score_codex":0.00004891857,"about_ca_system_score_gemma":0.000089838635,"threshold_uncertainty_score":0.5495139},"labels":[],"label_agreement":null},{"id":"W4416668786","doi":"10.3389/fgeed.2025.1740380","title":"Editorial: Social aspects of crop genome editing","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Genome Editing","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Multinational corporation; Public domain; Intellectual property; Discernment; Politics; Genome editing; Developing country; Promotion (chess)","score_opus":0.0033081315203943025,"score_gpt":0.25827760884079326,"score_spread":0.254969477320399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416668786","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00040953222,0.004127558,0.010164129,0.000031669926,0.9807915,0.00031653573,0.00058745657,0.000036845377,0.0035347692],"genre_scores_gemma":[0.0033354266,0.00039002224,0.00278365,0.000013685114,0.99050903,0.000052433967,0.0020484866,0.00011501651,0.00075222604],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965268,0.000088599845,0.0009196093,0.00091157685,0.00075389317,0.00079956476],"domain_scores_gemma":[0.9984626,0.00006809677,0.00048395785,0.00048149563,0.00040014638,0.000103656974],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007827486,0.00057070964,0.00088529056,0.00039331967,0.00016354748,0.00006310395,0.0007511402,0.0017734009,0.0000132834875],"category_scores_gemma":[0.0014289146,0.0007073069,0.00031974996,0.00034590313,0.00013438342,0.000008345521,0.00044749584,0.0010685755,0.0000022430181],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041122472,0.00003650249,0.000056497658,0.00050417165,0.00017571947,0.0000074521345,0.0002005653,0.0006516506,0.022583092,0.000005935628,0.9751172,0.0006200573],"study_design_scores_gemma":[0.00075788266,0.00010492181,0.000058748214,0.00014468103,0.000082590675,6.523094e-7,0.00035580044,0.000032997672,0.002958191,0.000099552875,0.9948681,0.0005359107],"about_ca_topic_score_codex":0.000042901003,"about_ca_topic_score_gemma":0.00002465288,"teacher_disagreement_score":0.019750835,"about_ca_system_score_codex":0.00019001955,"about_ca_system_score_gemma":0.0005780797,"threshold_uncertainty_score":0.9995378},"labels":[],"label_agreement":null},{"id":"W4416752618","doi":"10.1016/j.tibtech.2025.10.022","title":"Creating artificial miR2118a/b to boost yield and broad-spectrum resistance in soybean via CRISPR/Cas9-targeted mutation","year":2025,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Agricultural Science and Technology Innovation Program; Chinese Academy of Agricultural Sciences; Youth Innovation Promotion Association of the Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Mutant; Biogenesis; Soybean cyst nematode; Gene; Pseudomonas syringae; Crop; Mutation; Yield (engineering)","score_opus":0.007882762428897691,"score_gpt":0.2946512680960987,"score_spread":0.286768505667201,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416752618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9636125,0.0021603971,0.027619855,0.0046361857,0.00016730445,0.00015121684,0.000009686371,0.000059323138,0.0015835079],"genre_scores_gemma":[0.9958257,0.000064069456,0.0030710509,0.00015381107,0.00003492607,0.000028124055,0.000030049076,0.0000139626345,0.00077827874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988937,0.000018461526,0.00028193835,0.00043924584,0.000051985222,0.00031467594],"domain_scores_gemma":[0.9996142,0.000018975456,0.00003467959,0.00028631595,0.000012739931,0.000033101398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012824511,0.00015722318,0.00018299196,0.0005826644,0.000045638313,0.000014390162,0.00014423917,0.00039387762,0.000012711502],"category_scores_gemma":[0.0001304016,0.00018099035,0.000029377286,0.0006410294,0.0000659079,0.0000029377131,0.000115889896,0.00020370493,0.0000021873816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012050707,0.00004731298,0.001945837,0.000023095852,0.0000163402,0.000021940907,0.00013198394,0.00022198269,0.9613183,0.0020193618,0.00049306615,0.033640273],"study_design_scores_gemma":[0.00039874404,0.0001458092,0.018776296,0.0000578746,0.000008210915,0.000007999944,0.00016243463,0.00032006748,0.9723477,0.0011665735,0.006370751,0.00023756133],"about_ca_topic_score_codex":0.00012799312,"about_ca_topic_score_gemma":0.008456382,"teacher_disagreement_score":0.03340271,"about_ca_system_score_codex":0.000029340397,"about_ca_system_score_gemma":0.000016849775,"threshold_uncertainty_score":0.7380572},"labels":[],"label_agreement":null},{"id":"W4416782906","doi":"10.1038/s41598-025-26759-7","title":"A buffer-tuning strategy to profile domain-specific activity of chimeric I-TevI/CRISPR gene editors in vitro","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Government of Ontario","keywords":"Nuclease; Cleavage (geology); In vitro; Gene; Fusion gene; DNA; Fusion protein","score_opus":0.007056953204863131,"score_gpt":0.28364537459119393,"score_spread":0.2765884213863308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416782906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9733979,0.000594204,0.018738465,0.00004210981,0.0057451464,0.00035331873,0.0000060415837,0.000014422219,0.0011083772],"genre_scores_gemma":[0.9957126,0.000011922433,0.002798387,0.000010049068,0.00028884996,0.000041166484,0.000054543092,0.00001395075,0.0010685626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834967,0.00003575768,0.00037791693,0.0006951103,0.00022070429,0.0003208542],"domain_scores_gemma":[0.9989613,0.000009055503,0.00010750743,0.00073657377,0.00009636252,0.000089152265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006053607,0.00016137771,0.00021815328,0.00023354698,0.00008286634,0.00005719867,0.00015542695,0.000102319565,0.000017792145],"category_scores_gemma":[0.00004498932,0.00016440477,0.000089699824,0.00064185035,0.00008948515,0.000005833655,0.00014924289,0.0000975617,0.0000028880145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040352166,0.00006479752,0.00053486566,0.00003187535,0.000015443196,0.000027532658,0.00006135558,0.0009196502,0.98667425,0.000006714791,0.0065922188,0.0050309384],"study_design_scores_gemma":[0.00012232365,0.000052964024,0.0026645279,0.000027124568,0.000005290853,0.000016181348,0.00006706725,0.000047349895,0.9381224,0.00009512921,0.058634315,0.00014530557],"about_ca_topic_score_codex":0.000028566996,"about_ca_topic_score_gemma":0.000014480242,"teacher_disagreement_score":0.052042097,"about_ca_system_score_codex":0.00002926488,"about_ca_system_score_gemma":0.00016135357,"threshold_uncertainty_score":0.6704232},"labels":[],"label_agreement":null},{"id":"W4416940190","doi":"10.1016/j.xplc.2025.101632","title":"Development of dual base editors based on ssDNA-targeting SCP1.201 deaminases for the artificial evolution of novel herbicide-tolerant OsEPSPS variants","year":2025,"lang":"en","type":"article","venue":"Plant Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Major Science and Technology Projects in Anhui Province; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Dual (grammatical number); Base (topology); Development (topology); Artificial life; Biological evolution","score_opus":0.02508965424560237,"score_gpt":0.3076944208600255,"score_spread":0.28260476661442313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416940190","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2427247,0.001495328,0.7528781,0.0007048339,0.0007077917,0.00062704226,0.00047748574,0.00001794571,0.00036674127],"genre_scores_gemma":[0.9615262,0.00002404354,0.03788019,0.000027747892,0.0001060522,0.00006861027,0.00034234056,0.000007663713,0.000017136932],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933434,0.00002809755,0.00031187138,0.00012208054,0.00008484782,0.00011876113],"domain_scores_gemma":[0.998939,0.00025619444,0.00009222853,0.00059638644,0.00009588941,0.00002030865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031666615,0.00008978465,0.000107187625,0.0000589953,0.00019131071,0.0000067039123,0.00030757074,0.000061179024,0.0000023066],"category_scores_gemma":[0.00020944423,0.00007655256,0.00005677834,0.00009688962,0.00005811079,0.000001862999,0.000110140325,0.00006346617,3.6744552e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009520105,0.00035257454,0.00024916005,0.000065615655,0.00007567115,6.883031e-8,0.00013248649,0.013076405,0.981575,0.0013385264,0.0012442305,0.0017950224],"study_design_scores_gemma":[0.0006114651,0.00008202614,0.0055451845,0.00019072086,0.00007445108,0.0000010510348,0.0006195753,0.14443977,0.8278875,0.000033266526,0.020350136,0.0001648659],"about_ca_topic_score_codex":0.000034871227,"about_ca_topic_score_gemma":0.00014020732,"teacher_disagreement_score":0.7188015,"about_ca_system_score_codex":0.000019334431,"about_ca_system_score_gemma":0.00019337406,"threshold_uncertainty_score":0.31217226},"labels":[],"label_agreement":null},{"id":"W4416953451","doi":"","title":"Prophage induction and curing using CRISPR interference, a swiss knife army for prophage studies","year":2020,"lang":"en","type":"article","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Prophage; CRISPR; Curing (chemistry); Lysogen","score_opus":0.02848929896890863,"score_gpt":0.29624893467777963,"score_spread":0.267759635708871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416953451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69133484,0.003367713,0.30293584,0.0016284008,0.000064148066,0.00030043852,0.0000087710505,0.000033649983,0.0003261966],"genre_scores_gemma":[0.97683865,0.00029343323,0.022325365,0.00006321052,0.000051548766,0.00002308692,0.0000302353,0.000019883684,0.0003545796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990053,0.00023588004,0.00018202563,0.000341097,0.0000740228,0.00016165269],"domain_scores_gemma":[0.99907327,0.0000558,0.0000777284,0.00027827357,0.00042877218,0.00008618411],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054626964,0.00012973911,0.00013278496,0.000034006935,0.00014556419,0.00006241858,0.00016220435,0.00006670209,0.0000040630143],"category_scores_gemma":[0.0006201471,0.00013022136,0.000049249564,0.00010556966,0.00007901707,0.000010316862,0.00021950652,0.000085566426,0.0000011223647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026747519,0.000060550257,0.00049935374,0.00022685113,0.000067909205,0.0000011062144,0.0040131053,0.00011851505,0.97953975,0.00086909294,0.00019985466,0.01437715],"study_design_scores_gemma":[0.00044798618,0.0000038348458,0.00044399442,0.00016858472,0.00002785544,0.000009642134,0.00046518547,0.009011181,0.98608255,0.00012712748,0.0030255048,0.00018655778],"about_ca_topic_score_codex":0.000019117328,"about_ca_topic_score_gemma":0.000037436123,"teacher_disagreement_score":0.2855038,"about_ca_system_score_codex":0.0000120955965,"about_ca_system_score_gemma":0.00004052517,"threshold_uncertainty_score":0.5310273},"labels":[],"label_agreement":null},{"id":"W4416956232","doi":"10.1016/j.crmeth.2025.101248","title":"FAME-CRISPR improves CRISPR-Cas9 genome editing via HDAC inhibition and engineered virus-like particle delivery","year":2025,"lang":"en","type":"article","venue":"Cell Reports Methods","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Cumming School of Medicine, University of Calgary","keywords":"Genome editing; Histone deacetylase; CRISPR; Population; Transduction (biophysics); HDAC1; Gene; HDAC6; Selection (genetic algorithm); Histone","score_opus":0.007160042193896066,"score_gpt":0.312678263287829,"score_spread":0.30551822109393295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416956232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.53452903,0.0050524273,0.45876577,0.00003577176,0.0005737264,0.00017035358,0.0000032828764,0.00003740273,0.0008322367],"genre_scores_gemma":[0.9441451,0.00037907972,0.053786844,0.00020252712,0.0002472203,0.000038150138,0.0000516062,0.00003343993,0.0011160456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984759,0.00009034586,0.00044859943,0.00053918024,0.00010219399,0.00034379947],"domain_scores_gemma":[0.9991785,0.00004249584,0.000113456925,0.00044846535,0.00009443894,0.00012264325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073036854,0.00023016395,0.0002290048,0.00007151096,0.00010721671,0.000049596565,0.00006531088,0.00018429196,0.000014444363],"category_scores_gemma":[0.0001714675,0.00024340597,0.00010236297,0.0001484228,0.00005654393,0.0000092340715,0.0001749647,0.00014622281,0.0000014121218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013491348,0.000031342624,0.00024639335,0.00009062331,0.000036067722,0.00003680519,0.00006516006,0.00031966565,0.9814107,0.000004837423,0.00040955064,0.017335363],"study_design_scores_gemma":[0.00022348309,0.00007110868,0.0019672883,0.000017664648,0.000064157924,0.00006551947,0.000108807115,0.0013455751,0.95905244,0.0001106351,0.036736954,0.0002363691],"about_ca_topic_score_codex":0.000041057672,"about_ca_topic_score_gemma":0.000007387752,"teacher_disagreement_score":0.40961605,"about_ca_system_score_codex":0.000020285877,"about_ca_system_score_gemma":0.00004727897,"threshold_uncertainty_score":0.9925808},"labels":[],"label_agreement":null},{"id":"W4417004914","doi":"10.1182/blood-2025-1048","title":"Lipid nanoparticle-mediated epitope editing in human HSPCs enables resistance to CD45-directed CAR-T cell therapy","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"WSP (Canada)","funders":"","keywords":"Epitope; Electroporation; Haematopoiesis; Ex vivo; Stem cell; Genome editing; Progenitor cell","score_opus":0.004866321082779813,"score_gpt":0.25680457486220243,"score_spread":0.25193825377942264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417004914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99435556,0.0033407223,0.0001605803,0.00016230131,0.00019767834,0.00019400558,0.000008644219,0.000045122353,0.0015354019],"genre_scores_gemma":[0.99752945,0.00020706288,0.000511168,0.00020170952,0.00024709766,0.000045407513,0.000032705135,0.000018668934,0.001206751],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907094,0.000036308185,0.00021321012,0.0003082402,0.0000785101,0.00029276148],"domain_scores_gemma":[0.9995632,0.000014409307,0.000027673374,0.00028246467,0.000048919068,0.00006330852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256757,0.00013842274,0.0001390329,0.00007474512,0.0000612721,0.000025032168,0.00017359604,0.000096004085,0.000008897893],"category_scores_gemma":[0.00008132772,0.0001459174,0.000041385945,0.00027265673,0.000017914033,0.0000023267928,0.00007062758,0.0000761366,0.0000039691904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002160112,0.00013136202,0.0065182145,0.00002379826,0.0000196352,0.0000048470356,0.00008036104,0.00015383835,0.99082255,0.000012048565,0.0019083867,0.0003033296],"study_design_scores_gemma":[0.0012011045,0.00006698552,0.0072797355,0.000040698716,0.0000095116675,4.6511659e-7,0.000057071167,0.000017742115,0.9667122,0.000013305724,0.02445,0.00015122641],"about_ca_topic_score_codex":0.00004129303,"about_ca_topic_score_gemma":0.00037151598,"teacher_disagreement_score":0.024110425,"about_ca_system_score_codex":0.000009097874,"about_ca_system_score_gemma":0.00003599855,"threshold_uncertainty_score":0.5950339},"labels":[],"label_agreement":null},{"id":"W4417015463","doi":"10.5376/mgg.2025.16.0027","title":"CRISPRCas9-Mediated Knockout of Drought-Sensitive Genes Improves Maize Tolerance","year":2025,"lang":"","type":"article","venue":"Maize Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Drought tolerance; Genome editing; CRISPR; Gene; Genome; Gene knockout; Zea mays; Resilience (materials science); Drought stress","score_opus":0.004085958460592434,"score_gpt":0.25794752315575464,"score_spread":0.2538615646951622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417015463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.875386,0.104321174,0.01571399,0.00043358086,0.0012908864,0.00071429776,0.00039315748,0.000018103487,0.0017287788],"genre_scores_gemma":[0.93456376,0.056661606,0.0055819345,0.00044445798,0.00043392755,0.000023633347,0.00012566522,0.00008447427,0.0020805148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996716,0.000096690805,0.001059977,0.0010957062,0.00021278189,0.00081884064],"domain_scores_gemma":[0.9980408,0.00008975424,0.00030054033,0.0009477991,0.00036620093,0.0002549331],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031225375,0.0007218582,0.00082932337,0.00020244396,0.00021452291,0.000107285414,0.00043522628,0.00057356944,0.00001630173],"category_scores_gemma":[0.0000914092,0.0008247763,0.00028536955,0.0003376409,0.00044602397,0.000006173481,0.0007008663,0.00029296245,0.000007703514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028080304,0.00014508874,0.0013843349,0.0005534793,0.00052289973,0.000012830554,0.00032105861,0.0022968163,0.94579285,0.00018776016,0.0007306082,0.04777145],"study_design_scores_gemma":[0.0022902593,0.00055690936,0.008373787,0.00014665557,0.00041525555,0.000036021822,0.0007066177,0.010442927,0.83328456,0.00027576849,0.14246204,0.001009203],"about_ca_topic_score_codex":0.000038714414,"about_ca_topic_score_gemma":0.000069826005,"teacher_disagreement_score":0.14173143,"about_ca_system_score_codex":0.00005491346,"about_ca_system_score_gemma":0.0004107265,"threshold_uncertainty_score":0.9994203},"labels":[],"label_agreement":null},{"id":"W4417015486","doi":"10.5376/lgg.2025.16.0008","title":"CRISPR/Cas9-Mediated Knockout of Trypsin Inhibitor Genes in Soybean","year":2025,"lang":"","type":"article","venue":"Legume Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Trypsin inhibitor; Gene; Genome editing; Limiting; Transcriptome; Genome; Trypsin","score_opus":0.004905765057266734,"score_gpt":0.2700025401406441,"score_spread":0.26509677508337737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417015486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89103425,0.10223488,0.0036640097,0.0003529834,0.00096121046,0.00053065293,0.00017614593,0.000009708138,0.0010361894],"genre_scores_gemma":[0.96846336,0.027255893,0.0025843754,0.00023296083,0.0003343608,0.000019210327,0.00011242678,0.00006761004,0.00092977326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970268,0.00009257882,0.0011040268,0.00089126395,0.00017545285,0.00070985785],"domain_scores_gemma":[0.99860305,0.000055317338,0.00020635538,0.0007715009,0.00015881468,0.00020493714],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033414987,0.0005700581,0.0006841772,0.0003483384,0.000101436905,0.000074841075,0.00039634286,0.00069386413,0.000019588266],"category_scores_gemma":[0.00007502828,0.0006743283,0.00016979812,0.00041202886,0.000285669,0.0000052025107,0.0005320985,0.00030798896,0.0000054449183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019147625,0.00024005196,0.0139048,0.000572817,0.00025344588,0.0000117272175,0.0004448089,0.0027964523,0.93845356,0.00015175856,0.00063717057,0.042341933],"study_design_scores_gemma":[0.0028898746,0.00056204165,0.014444972,0.0002015081,0.00019825072,0.000015940233,0.00069696206,0.005833696,0.85288066,0.00032080486,0.12102806,0.0009272183],"about_ca_topic_score_codex":0.000050048526,"about_ca_topic_score_gemma":0.00027127602,"teacher_disagreement_score":0.120390885,"about_ca_system_score_codex":0.000061699575,"about_ca_system_score_gemma":0.00041546096,"threshold_uncertainty_score":0.9995708},"labels":[],"label_agreement":null},{"id":"W4417015502","doi":"10.5376/lgg.2025.16.0014","title":"CRISPR Activation System for Flowering Regulation in Mung Bean","year":2025,"lang":"","type":"article","venue":"Legume Genomics and Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Mung bean; Gene; Identification (biology); Genome editing; Multiplex; Crop","score_opus":0.005403062806473483,"score_gpt":0.2724163302519524,"score_spread":0.26701326744547893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417015502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67594,0.009947235,0.31113344,0.00025949546,0.00096892955,0.0009253977,0.000045318648,0.000014819685,0.00076538534],"genre_scores_gemma":[0.99070585,0.0018335097,0.006154889,0.00009284191,0.0003959373,0.000060315004,0.00012909516,0.0000530587,0.0005745184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807405,0.000038773967,0.0006294559,0.00068472966,0.0000940094,0.00047899177],"domain_scores_gemma":[0.99914676,0.00003704936,0.00012257445,0.0004796702,0.00011736005,0.00009660803],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033295952,0.00035918588,0.0003423246,0.00020916805,0.00018022885,0.000122063895,0.00019483386,0.00043571898,0.0000023476648],"category_scores_gemma":[0.00004034906,0.00045435,0.000120217985,0.00018974078,0.000057969897,0.000006907352,0.00020114584,0.00014782828,0.0000010144738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019722336,0.00005695214,0.0013632685,0.0010993464,0.00014369286,0.0000010874164,0.00036726624,0.041781615,0.90851694,0.0009401159,0.00021014099,0.045322366],"study_design_scores_gemma":[0.0021931804,0.00023177407,0.008796563,0.0003420835,0.00013734783,0.0000075449584,0.0008465863,0.110330224,0.8191504,0.00028826867,0.057017274,0.00065877393],"about_ca_topic_score_codex":0.000026656098,"about_ca_topic_score_gemma":0.000088019624,"teacher_disagreement_score":0.31476587,"about_ca_system_score_codex":0.0001544328,"about_ca_system_score_gemma":0.00015278584,"threshold_uncertainty_score":0.99979085},"labels":[],"label_agreement":null},{"id":"W4417117055","doi":"10.64898/2025.12.02.690677","title":"Improved cloning-free one-step CRISPR-Cas12a-assisted tagging of mammalian genes using PCR generated reagents (PCR tagging)","year":2025,"lang":"","type":"article","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Baden-Württemberg Stiftung","keywords":"Concatemer; Gene; DNA; Genome engineering; DNA sequencing; CRISPR; Genome","score_opus":0.013918392449643572,"score_gpt":0.2593937666927917,"score_spread":0.2454753742431481,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417117055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9122063,0.016277608,0.067076124,0.0002925133,0.0024641156,0.0011037968,0.00037215633,0.00016331559,0.000044059416],"genre_scores_gemma":[0.97118074,0.0013034429,0.025970777,0.0004195177,0.00071218243,0.0000705924,0.0000038742696,0.0002620671,0.000076789984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.993829,0.00029464083,0.0017953252,0.0019541504,0.00052923796,0.001597655],"domain_scores_gemma":[0.99453753,0.000050106177,0.00073255587,0.002988523,0.0011681792,0.00052311696],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00092371687,0.0012282651,0.0012356215,0.00063504634,0.00053236523,0.00028187246,0.0013504485,0.0011138031,0.00005796598],"category_scores_gemma":[0.0005877846,0.001529128,0.00051018695,0.0017105163,0.0003469273,0.00004628469,0.0010065419,0.0005856815,0.000007804266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002208447,0.00036665273,0.0028940346,0.001000518,0.0010005248,0.00004120008,0.000012991421,0.0013004965,0.9925294,0.00013999018,0.00041828165,0.00007507115],"study_design_scores_gemma":[0.0026973025,0.00024381846,0.009015746,0.00073749345,0.00077800546,2.5902753e-7,0.000023760014,0.01975933,0.95096,3.74986e-7,0.01442556,0.0013583428],"about_ca_topic_score_codex":0.0003129788,"about_ca_topic_score_gemma":0.00003769601,"teacher_disagreement_score":0.05897444,"about_ca_system_score_codex":0.00030679765,"about_ca_system_score_gemma":0.0011353169,"threshold_uncertainty_score":0.99871576},"labels":[],"label_agreement":null},{"id":"W4417132935","doi":"10.64898/2025.12.06.692781","title":"Conjugation Based CRISPR Antifungals (COBRA)","year":2025,"lang":"","type":"article","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Electroporation; Plasmid; Yeast; Cas9; Gene; Genome editing","score_opus":0.006274317567879451,"score_gpt":0.2517550132914194,"score_spread":0.24548069572353998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417132935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6492604,0.019615514,0.32392797,0.0012289694,0.0038796905,0.0013113747,0.00028522717,0.0002396664,0.00025117872],"genre_scores_gemma":[0.99477017,0.0006445588,0.0028492142,0.001006633,0.0004774171,0.000078477904,0.0000011725967,0.00011085304,0.00006150158],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99676687,0.00015432807,0.0007272875,0.0012012986,0.000302231,0.0008480126],"domain_scores_gemma":[0.9974845,0.000055671928,0.00021645757,0.0013709236,0.00057529326,0.00029712715],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005347319,0.000663303,0.0005140899,0.00031360175,0.00031006633,0.00023885746,0.00052958075,0.00069679815,0.000084348336],"category_scores_gemma":[0.0004127126,0.0008114807,0.00026529742,0.0008830905,0.00019105381,0.000018849823,0.00019174871,0.0003517022,0.00006736543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079143836,0.00017867913,0.008826785,0.00039604332,0.00022111842,0.000014569605,0.000002485496,0.0005112227,0.9869644,0.00081480446,0.0019786698,0.000012054597],"study_design_scores_gemma":[0.0012786019,0.00013396674,0.035096973,0.00027771766,0.00018647591,9.263889e-9,0.000004988853,0.0029665246,0.8966184,5.5674843e-7,0.0627062,0.0007295467],"about_ca_topic_score_codex":0.000016018153,"about_ca_topic_score_gemma":0.000002940522,"teacher_disagreement_score":0.34550974,"about_ca_system_score_codex":0.000113109585,"about_ca_system_score_gemma":0.00086924166,"threshold_uncertainty_score":0.9994336},"labels":[],"label_agreement":null},{"id":"W4417181862","doi":"10.3389/fpls.2025.1718810","title":"AI-driven advances in plant biotechnology: sharpening the edge of plant tissue culture and genome editing","year":2025,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Lethbridge; National Research Council Canada","funders":"","keywords":"Genome editing; CRISPR; Genome; Deep learning; Artificial neural network; Sharpening","score_opus":0.0030458397642028267,"score_gpt":0.2525321759695638,"score_spread":0.24948633620536095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417181862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85885984,0.048080117,0.087177284,0.0010508932,0.0022794884,0.00069216377,0.0006949628,0.00003405982,0.0011311768],"genre_scores_gemma":[0.9927376,0.0025727144,0.0044243983,0.00009741366,0.000047895355,0.000011450623,0.000048600235,0.0000041712447,0.000055748562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919724,0.000011878047,0.00016601747,0.00029157166,0.00009334936,0.00023995725],"domain_scores_gemma":[0.9997471,0.000008747147,0.00004251304,0.00016357016,0.000013457626,0.00002461688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002550675,0.00009652016,0.0001351491,0.00016666563,0.00007448161,0.00001682453,0.00035836393,0.000094843526,5.761552e-7],"category_scores_gemma":[0.00007273857,0.000073695344,0.000012825339,0.00032051356,0.00029452128,0.000010735373,0.00017149451,0.00014575812,1.4429446e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035718436,0.000017335824,0.025325628,0.00006805172,0.000009298053,0.000014439598,0.0004902381,0.0034973337,0.9645942,0.00045372377,0.0014368276,0.00405724],"study_design_scores_gemma":[0.0006032168,0.000146657,0.012960673,0.00029945778,0.000012453954,0.00006106996,0.0021854977,0.011730956,0.8114394,0.00027936176,0.15997507,0.00030620335],"about_ca_topic_score_codex":0.000011184421,"about_ca_topic_score_gemma":0.00007186017,"teacher_disagreement_score":0.15853825,"about_ca_system_score_codex":0.000016412576,"about_ca_system_score_gemma":0.000049536167,"threshold_uncertainty_score":0.3005209},"labels":[],"label_agreement":null},{"id":"W4417261578","doi":"10.1073/pnas.2536003123","title":"Anti-CRISPR-mediated continuous directed evolution of CRISPR-Cas9 in human cells","year":2025,"lang":"en","type":"preprint","venue":"Proceedings of the National Academy of Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Defense Sciences Office, DARPA; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institute of Environmental Health Sciences; Defense Advanced Research Projects Agency; National Science Foundation; National Cancer Institute; Damon Runyon Cancer Research Foundation","keywords":"Directed evolution; Directed Molecular Evolution; CRISPR; Cas9; Function (biology); Mutation; Adaptive evolution; Key (lock); Experimental evolution","score_opus":0.01535512309848799,"score_gpt":0.3249431946526954,"score_spread":0.3095880715542074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417261578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959868,0.0009834436,0.00004561768,0.00021535442,0.000075292024,0.00030009318,0.000106500556,0.000009447723,0.0022774204],"genre_scores_gemma":[0.9988024,0.0001473309,0.000723582,0.00002681138,0.00006611492,0.000013260169,0.0000034771306,0.000005097271,0.00021190595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983982,0.000010588392,0.0005130947,0.00037035448,0.00054404826,0.00016371187],"domain_scores_gemma":[0.99906707,0.000032825308,0.00047122547,0.000022256598,0.00038197212,0.000024644663],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007758928,0.00015562419,0.0003016504,0.00026947263,0.000055208908,0.0000109002,0.0008093005,0.00030693485,0.0000037945154],"category_scores_gemma":[0.0004151031,0.00012985188,0.00012380134,0.0004684489,0.00040665333,0.000007835842,0.0005334121,0.0002563804,1.4392916e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009302181,0.00005191186,0.0077072904,0.0002764737,0.000025694628,5.161226e-9,0.00005571466,0.002356794,0.988022,0.00083682756,0.0006148981,0.000043057906],"study_design_scores_gemma":[0.00019038227,0.000037371305,0.057683915,0.00028145956,0.000018897872,8.3427597e-7,0.00008100021,0.0009869422,0.93830293,0.0021242779,0.00017358235,0.00011840203],"about_ca_topic_score_codex":0.00005386323,"about_ca_topic_score_gemma":0.0000010388429,"teacher_disagreement_score":0.049976625,"about_ca_system_score_codex":0.000033597964,"about_ca_system_score_gemma":0.00009346808,"threshold_uncertainty_score":0.5295206},"labels":[],"label_agreement":null},{"id":"W4417278213","doi":"10.1038/s41467-025-67201-w","title":"Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"Genentech","keywords":"CRISPR; Cas9; Genome editing; Nuclease; Genome engineering; Context (archaeology); Synthetic biology; Systems biology; DNA","score_opus":0.009031890699239944,"score_gpt":0.32895486144259223,"score_spread":0.3199229707433523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417278213","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41350368,0.120111994,0.41985527,0.020038996,0.0020376523,0.0031814654,0.000561659,0.00029374822,0.020415535],"genre_scores_gemma":[0.987392,0.0013080173,0.008155626,0.0005681129,0.00006631158,0.00017315913,0.001027953,0.000020387586,0.0012884509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929297,0.000027644695,0.00017968715,0.00025644357,0.000066491564,0.00017673694],"domain_scores_gemma":[0.9983207,0.00007018259,0.00004191405,0.001337839,0.00018713449,0.000042216583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013393567,0.00013177238,0.00011883259,0.00006641541,0.00017445338,0.000023863015,0.00063580554,0.0003750272,0.000004593047],"category_scores_gemma":[0.0002784531,0.00014094415,0.00009583661,0.00017517603,0.00004693863,0.0000037624734,0.000112258625,0.00028943457,0.000002510302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011227324,0.00006580984,0.00020341483,0.000027892593,0.0000637811,8.187361e-8,0.000034622684,0.000089903515,0.98885596,0.0021557512,0.0054656216,0.0030259215],"study_design_scores_gemma":[0.00085278344,0.000054351163,0.0045894864,0.000031827072,0.00008431577,0.0000060933007,0.000053418324,0.0012907143,0.8182835,0.00069598155,0.1737769,0.00028063243],"about_ca_topic_score_codex":0.0000056091994,"about_ca_topic_score_gemma":0.00008321174,"teacher_disagreement_score":0.5738883,"about_ca_system_score_codex":0.00003173045,"about_ca_system_score_gemma":0.00006771062,"threshold_uncertainty_score":0.5747536},"labels":[],"label_agreement":null},{"id":"W4417415263","doi":"10.1093/infdis/jiaf609","title":"A Rapid Assay for Hepatitis C Virus RNA Detection Using Reverse-Transcription Loop-Mediated Isothermal Amplification–Coupled CRISPR-Cas12b–Based Strategy","year":2025,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Hepatitis C virus; Flaviviridae; RNA; Hepacivirus; Virus; Hepatitis C","score_opus":0.010428905422252645,"score_gpt":0.2861921519239494,"score_spread":0.27576324650169676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417415263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62454194,0.0019332488,0.37293553,0.00004463969,0.0002792401,0.00018781083,0.000039904848,0.000022561391,0.000015147573],"genre_scores_gemma":[0.99857694,0.00079309737,0.00012193956,0.00019762911,0.00022275432,0.000013535235,0.000023186229,0.000029552435,0.000021363521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915755,0.00011365564,0.00033012725,0.00011998861,0.00011419635,0.00016449056],"domain_scores_gemma":[0.9991958,0.00008111015,0.00019695026,0.0001812849,0.00027862648,0.000066197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031596923,0.0001424849,0.0001572172,0.0001186311,0.00016600099,0.000036748454,0.000118501725,0.00007710099,0.000012577677],"category_scores_gemma":[0.00022105758,0.00011718129,0.00018357519,0.00015902518,0.000047365185,0.000011502801,0.000010598802,0.00009944881,0.000001102205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037877174,0.00010542021,0.0015759433,0.00006038137,0.00015464793,0.0000011879374,0.000018246523,0.030906007,0.962299,0.0000051072557,0.00024157198,0.0042537525],"study_design_scores_gemma":[0.0041242717,0.0011883638,0.029891415,0.00014928024,0.0010953923,0.000076681965,0.00016598699,0.06975905,0.88954973,0.00024995822,0.0033285888,0.00042129686],"about_ca_topic_score_codex":0.00015723897,"about_ca_topic_score_gemma":0.00015778973,"teacher_disagreement_score":0.37403503,"about_ca_system_score_codex":0.00005326386,"about_ca_system_score_gemma":0.00016135027,"threshold_uncertainty_score":0.47785142},"labels":[],"label_agreement":null},{"id":"W4417461623","doi":"10.1093/synbio/ysaf020","title":"RAPID-DASH: fast and efficient assembly of guide RNA arrays for multiplexed CRISPR-Cas9 applications","year":2025,"lang":"en","type":"article","venue":"Synthetic Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Genome British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Scalability; Multiplexing; Guide RNA; RNA; Construct (python library)","score_opus":0.008336612209647445,"score_gpt":0.32496333898497387,"score_spread":0.31662672677532644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417461623","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11914903,0.0038793923,0.87349653,0.00034431234,0.00022558318,0.0006816197,0.00009262817,0.000019960855,0.0021109465],"genre_scores_gemma":[0.9893285,0.00022997471,0.009684568,0.00008382704,0.00006967836,0.00021350886,0.00005707693,0.000013570281,0.00031930057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991184,0.000029596895,0.00025935823,0.00034557228,0.000029730505,0.0002173269],"domain_scores_gemma":[0.9994062,0.00007357598,0.000058182675,0.00033493977,0.000082392195,0.00004468198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017683969,0.00013671996,0.00019708804,0.00007175442,0.00006174922,0.0000057780467,0.00014880554,0.00017391959,0.0000060232464],"category_scores_gemma":[0.0001235181,0.00012754457,0.00008295711,0.00007669421,0.0001399799,5.8118957e-7,0.000088191424,0.00004726892,0.0000013629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027997938,0.000045338442,0.00012333819,0.0000679041,0.000053851014,6.85275e-8,0.000022520371,0.00041591952,0.96399176,0.0018715158,0.00036569452,0.033014093],"study_design_scores_gemma":[0.00055871415,0.00015379804,0.00038863078,0.000019244027,0.000044425207,0.000004473575,0.0001031381,0.0022929416,0.8679446,0.00017660647,0.12816341,0.00015000664],"about_ca_topic_score_codex":0.000011902933,"about_ca_topic_score_gemma":0.000009195507,"teacher_disagreement_score":0.8701795,"about_ca_system_score_codex":0.000007057607,"about_ca_system_score_gemma":0.000042196032,"threshold_uncertainty_score":0.5201117},"labels":[],"label_agreement":null},{"id":"W4417478436","doi":"10.5376/mp.2025.16.0029","title":"Restoration of Cotton Disease Resistance by CRISPR-Mediated Disruption of Key Genes in Drug-Resistant Pathogens","year":2025,"lang":"","type":"article","venue":"Molecular Pathogens","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Gene; Key (lock); Disease; Plant disease resistance; Resistance (ecology); Genome; DNA Transposable Elements","score_opus":0.0035750159474936733,"score_gpt":0.2611427737027478,"score_spread":0.25756775775525415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417478436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8812679,0.0700569,0.045113623,0.000274951,0.00033703673,0.000745563,0.0017192455,0.000014445427,0.00047031522],"genre_scores_gemma":[0.99280727,0.004324334,0.00093735714,0.00007617108,0.000039419512,0.000065221146,0.0011251871,0.000061770166,0.0005632493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965304,0.0003601977,0.001239956,0.0008916176,0.0004306553,0.00054715655],"domain_scores_gemma":[0.99791574,0.00004610532,0.0003951533,0.0010730682,0.00035708147,0.00021285041],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049019087,0.0005040469,0.00062118913,0.0003198199,0.00007598412,0.000025696538,0.00036675791,0.00034990747,0.0000132958985],"category_scores_gemma":[0.00040825907,0.00060222397,0.00033917735,0.0007988354,0.00022473765,0.000010283264,0.00019125969,0.00019190412,0.0000023159291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077822135,0.0004053804,0.0034073119,0.0009450122,0.00012576878,0.000068312234,0.0002107989,0.002293366,0.98974895,0.00030380918,0.00070934196,0.0010036981],"study_design_scores_gemma":[0.0014457769,0.00015724501,0.00941079,0.0005475339,0.0002790159,0.0000010088158,0.00029157533,0.0008905165,0.9711496,0.00010979344,0.01513775,0.00057936565],"about_ca_topic_score_codex":0.000062191866,"about_ca_topic_score_gemma":0.00044465996,"teacher_disagreement_score":0.11153937,"about_ca_system_score_codex":0.00009561711,"about_ca_system_score_gemma":0.0003814715,"threshold_uncertainty_score":0.9996429},"labels":[],"label_agreement":null},{"id":"W49164610","doi":"10.1007/978-1-4614-6486-0_8","title":"Genomics, Other “Omic” Technologies, Personalized Medicine, and Additional Biotechnology-Related Techniques","year":2013,"lang":"en","type":"book-chapter","venue":"Pharmaceutical biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biotechnology; Drug development; Drug discovery; Personalized medicine; Computational biology; Pharmaceutical sciences; Function (biology); Emerging technologies; Biology; Drug; Bioinformatics; Computer science; Pharmacology; Genetics","score_opus":0.02125360957323118,"score_gpt":0.3125208855531937,"score_spread":0.2912672759799625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W49164610","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0037545913,0.26116288,0.02343889,0.18329553,0.0026804118,0.009589316,0.009515998,0.013434663,0.4931277],"genre_scores_gemma":[0.037387814,0.27794018,0.05354809,0.010267744,0.0027689312,0.0016392196,0.009044124,0.0021610218,0.6052429],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972449,0.000020681187,0.000658851,0.001229926,0.0002003676,0.00064529426],"domain_scores_gemma":[0.9986401,0.000062697574,0.00023117817,0.0008335341,0.00009249564,0.00013999017],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018304739,0.0007826348,0.00072883477,0.0005822814,0.00012373275,0.000020673653,0.00068101124,0.004760146,0.0047575384],"category_scores_gemma":[0.00021457228,0.0007432463,0.00017765377,0.00009913263,0.0031786964,0.000005455416,0.00075126474,0.001436045,0.00022137698],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007063287,0.000042663476,0.0000046832183,0.00010992158,0.00062078953,0.000029806313,0.000013261887,0.0000010861788,0.54850525,0.19863789,0.11499291,0.13697112],"study_design_scores_gemma":[0.0005223718,0.00025776261,0.0000012022077,0.00009673593,0.00011275716,0.0002605545,0.000027225882,0.00007200275,0.22739886,0.009411436,0.76123464,0.00060445035],"about_ca_topic_score_codex":0.000008422815,"about_ca_topic_score_gemma":0.0000052263713,"teacher_disagreement_score":0.6462417,"about_ca_system_score_codex":0.00007496047,"about_ca_system_score_gemma":0.00007744559,"threshold_uncertainty_score":0.9995341},"labels":[],"label_agreement":null},{"id":"W56051850","doi":"10.1007/978-1-4020-5799-1_18","title":"TAC–TICS: TRANSPOSON-BASED BIOLOGICAL PEST MANAGEMENT SYSTEMS","year":2007,"lang":"en","type":"book-chapter","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transposable element; Biology; Population; Transformation (genetics); Genetics; Gene; Insect; Computational biology; Mutant; Ecology; Medicine","score_opus":0.0207194570065571,"score_gpt":0.2782192219598917,"score_spread":0.2574997649533346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W56051850","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00048097235,0.0049040434,0.1688579,0.000033938137,0.00062605384,0.0005788973,0.00007216275,0.000078831545,0.8243672],"genre_scores_gemma":[0.18445781,0.0022882868,0.005030945,0.00048383317,0.0012568496,0.000046217592,0.0014352484,0.0001802532,0.80482054],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986818,0.0000071171385,0.00032298052,0.0005151924,0.0001696394,0.00030329317],"domain_scores_gemma":[0.9993059,0.000011500088,0.000057390593,0.0004559712,0.00004973546,0.00011948376],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014399788,0.00037814947,0.0002751535,0.000092638744,0.000039024184,0.00002447865,0.00023104665,0.0006009364,0.0002120284],"category_scores_gemma":[0.0000025299175,0.00033145657,0.0002138881,0.000015760963,0.000062597406,4.8498856e-7,0.00004644972,0.00015917321,0.000067061126],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015544301,0.0008083344,0.0008875048,0.007146251,0.006506018,0.0021660838,0.00012409264,0.058639374,0.15950646,0.57654154,0.08115645,0.10496344],"study_design_scores_gemma":[0.00050365296,0.00030180247,0.00006172203,0.00011437377,0.000093332375,0.000015886222,0.000017275363,0.0003034463,0.0071393885,0.00009010494,0.99067414,0.00068488903],"about_ca_topic_score_codex":0.0000060979146,"about_ca_topic_score_gemma":0.000012480545,"teacher_disagreement_score":0.9095177,"about_ca_system_score_codex":0.000020966889,"about_ca_system_score_gemma":0.000022075446,"threshold_uncertainty_score":0.99991375},"labels":[],"label_agreement":null},{"id":"W578808212","doi":"10.71781/29488","title":"Rôles de BRCA1 dans la régulation de la recombinaison homologue : implications pour le maintien de la stabilité du génome humain et la carcinogenèse","year":2007,"lang":"fr","type":"dissertation","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Institute of Cancer Research; Université de Montréal; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; Ludwig Institute for Cancer Research; University of Pennsylvania","keywords":"Political science; Biology; Philosophy","score_opus":0.010476008330866085,"score_gpt":0.35895220368760605,"score_spread":0.34847619535673996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W578808212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9403875,0.0008077626,0.031889517,0.00019220845,0.00008034516,0.00045884264,0.0001578982,0.0000046016125,0.026021348],"genre_scores_gemma":[0.97459596,0.00038671657,0.020003779,0.000031150543,0.00011206344,0.000098211414,0.0023820794,0.00007717616,0.0023128386],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975934,0.00082791597,0.0004090667,0.0005936386,0.00008666924,0.00048931467],"domain_scores_gemma":[0.99867845,0.00037403355,0.00017124173,0.0004871611,0.0001066942,0.00018239606],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021842232,0.000354301,0.0002957081,0.00010546191,0.00021203431,0.00024441053,0.0005363962,0.001005998,0.00008695311],"category_scores_gemma":[0.00028373807,0.000435994,0.00016621864,0.00014139988,0.00018900979,0.000014936387,0.00015019419,0.00039293815,0.00001259767],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101810256,0.00045199133,0.046537954,0.00011000308,0.00014877848,0.00004376569,0.0075852494,0.0067698644,0.9093849,0.0020849071,0.00022463132,0.026556112],"study_design_scores_gemma":[0.0010785598,0.00015170245,0.6057495,0.0001164644,0.00018051015,0.00042200525,0.005366108,0.0007086567,0.34350747,0.0013151824,0.040751863,0.00065200275],"about_ca_topic_score_codex":0.0019290642,"about_ca_topic_score_gemma":0.002209626,"teacher_disagreement_score":0.56587744,"about_ca_system_score_codex":0.00016939359,"about_ca_system_score_gemma":0.0011627402,"threshold_uncertainty_score":0.9998092},"labels":[],"label_agreement":null},{"id":"W616296877","doi":"10.1038/ncomms8391","title":"Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":301,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Partenariat Canadien Contre Le Cancer; National Institute of Allergy and Infectious Diseases; Deutsche Krebshilfe; Deutsches Krebsforschungszentrum","keywords":"CRISPR; Carcinogenesis; Somatic cell; PTEN; Biology; Medulloblastoma; Suppressor; Gene; Cas9; Computational biology; Cancer research; Tumor suppressor gene; Genetics; Apoptosis","score_opus":0.023951724509417682,"score_gpt":0.32619601337557086,"score_spread":0.3022442888661532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W616296877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7745253,0.043270983,0.16148806,0.011570874,0.00083009934,0.0010496625,0.00025711936,0.00028510552,0.006722796],"genre_scores_gemma":[0.988068,0.00035310193,0.009988342,0.00022196185,0.00012713819,0.000047601254,0.0009213453,0.000032901764,0.00023964286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990645,0.00010052901,0.00022194785,0.00022262459,0.00016035922,0.00023005555],"domain_scores_gemma":[0.998451,0.00008121573,0.000069806476,0.0010843389,0.00017392602,0.00013973143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025493695,0.00016305012,0.00013853033,0.00006627871,0.00013797803,0.000042938165,0.00065691664,0.00028068072,0.000007421764],"category_scores_gemma":[0.00040070945,0.00016636853,0.000073739626,0.00015007879,0.000059320304,0.000010285315,0.0002962249,0.00039943104,0.000026210417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040934,0.00019967767,0.00069504406,0.000043982418,0.00009052961,0.0000024213698,0.000831683,0.03695385,0.92824966,0.0007497255,0.03182624,0.00031628154],"study_design_scores_gemma":[0.0023465373,0.0002746777,0.0023580857,0.000116516196,0.00014566876,0.00006425427,0.002098913,0.3256791,0.36466572,0.00084729935,0.300299,0.001104264],"about_ca_topic_score_codex":0.000028228067,"about_ca_topic_score_gemma":0.00013970335,"teacher_disagreement_score":0.5635839,"about_ca_system_score_codex":0.000030181134,"about_ca_system_score_gemma":0.0000810198,"threshold_uncertainty_score":0.67843115},"labels":[],"label_agreement":null},{"id":"W631747042","doi":"","title":"Pratique de l'éthique appliquée dans les comités d'éthique en Europe et au Canada : le cas des plantes transgéniques","year":2009,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Humanities; Philosophy; Political science","score_opus":0.009485303961785376,"score_gpt":0.25668933932818505,"score_spread":0.24720403536639968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W631747042","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.33312976,0.0013700266,0.63587487,0.0040745432,0.00006789512,0.0003930651,0.0001493695,0.000090368674,0.02485013],"genre_scores_gemma":[0.96034443,0.0025513126,0.034173824,0.0003469521,0.00006174388,0.000083886756,0.00093946094,0.00006901725,0.001429347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99404424,0.0042543113,0.00042181424,0.0006626671,0.00019925415,0.00041769244],"domain_scores_gemma":[0.9972758,0.00042607324,0.00019015855,0.0011598178,0.00074436155,0.0002037607],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0033620042,0.00040755508,0.00032049604,0.00006296261,0.00024165874,0.00014055923,0.0008915254,0.0007165106,0.000008791221],"category_scores_gemma":[0.0009827954,0.0004556598,0.00014209018,0.00011526955,0.00015453284,0.000008092353,0.000450925,0.0010679328,9.845322e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008355765,0.0007013401,0.011332457,0.0009672367,0.00037040026,0.00006486592,0.030119024,0.009040505,0.8500193,0.07211795,0.0028114717,0.022371897],"study_design_scores_gemma":[0.0003255016,0.0000026335872,0.0141251795,0.0007845372,0.00003762826,0.00006741615,0.00025913873,0.0020020646,0.95585793,0.00090779114,0.02502036,0.0006098168],"about_ca_topic_score_codex":0.30390078,"about_ca_topic_score_gemma":0.8855745,"teacher_disagreement_score":0.6272147,"about_ca_system_score_codex":0.00019678529,"about_ca_system_score_gemma":0.0027483632,"threshold_uncertainty_score":0.99978954},"labels":[],"label_agreement":null},{"id":"W65673204","doi":"10.5840/jphil201010721","title":"Cohesion, Gene Flow, and the Nature of Species","year":2010,"lang":"en","type":"article","venue":"The Journal of Philosophy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cohesion (chemistry); Analytic philosophy; Gene flow; Contemporary philosophy; Philosophy; Epistemology; Biology; Gene; Genetics; Chemistry; Genetic variation","score_opus":0.004730510670059044,"score_gpt":0.24834166817204895,"score_spread":0.2436111575019899,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W65673204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99123263,0.004438134,0.0007861948,0.0023833597,0.0002990874,0.000050351755,0.0000041060175,9.4689545e-7,0.00080516556],"genre_scores_gemma":[0.9976861,0.00069724745,0.000588036,0.0001478642,0.00082730723,2.6725164e-7,8.3636615e-7,0.000006093836,0.0000462299],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996295,0.000028163477,0.00014902031,0.00003898811,0.00009695837,0.000057365665],"domain_scores_gemma":[0.99959576,0.00003197749,0.000096303025,0.00016549902,0.000084158106,0.000026322972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038443797,0.00005922165,0.00009773292,0.000017279526,0.00003790425,0.000005276854,0.00018384607,0.000070696966,0.000008595424],"category_scores_gemma":[0.00008057098,0.000028509796,0.00006127724,0.000031203177,0.00015682026,0.0000014591493,0.000050205344,0.00024998633,3.2497823e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016436868,0.000009965476,0.00013157792,0.000007701871,0.00004734338,7.8511863e-7,0.000112695714,0.00016935526,0.9975377,0.000881041,0.00067948684,0.00025799504],"study_design_scores_gemma":[0.0011094045,0.00017917716,0.0044150986,0.000014433928,0.000077500736,0.0003397758,0.000051730334,0.00009540339,0.9773168,0.00687123,0.00944979,0.00007966335],"about_ca_topic_score_codex":7.557331e-7,"about_ca_topic_score_gemma":0.0000019770696,"teacher_disagreement_score":0.02022089,"about_ca_system_score_codex":8.304988e-7,"about_ca_system_score_gemma":0.00001383715,"threshold_uncertainty_score":0.11625957},"labels":[],"label_agreement":null},{"id":"W6893656164","doi":"10.5281/zenodo.3686299","title":"Generation of Knockout Cell Lines Using CRISPR-Cas9 Technology","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cell culture; Cell; Genome; Set (abstract data type); Protocol (science)","score_opus":0.05297389630115775,"score_gpt":0.29405869083927016,"score_spread":0.2410847945381124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6893656164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82246745,0.0007738229,0.16987135,0.0006374105,0.00008910191,0.00026930196,0.000083236744,0.0001841531,0.0056241876],"genre_scores_gemma":[0.99712116,0.00008850007,0.0016414698,0.00007335333,0.00024471222,1.6291557e-8,0.00040701593,0.0003471088,0.00007665236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993045,0.000044206787,0.0001605005,0.00023983451,0.00009918629,0.00015179759],"domain_scores_gemma":[0.99942154,0.0000016233612,0.000053316213,0.00020737667,0.00024435393,0.00007176861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819455,0.00008444282,0.000087083026,0.0000752522,0.0002749443,0.000055167635,0.00031169588,0.00007900711,0.00042314833],"category_scores_gemma":[0.00018868063,0.00009438125,0.00003397552,0.00024228418,0.000056647612,0.000005361691,0.00042991142,0.00008336587,0.00012953125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000151489,0.000023993405,0.000005573675,0.00003917681,0.0000128383435,0.0000012939075,0.00012464478,0.0019370975,0.98059475,0.00007077826,0.00918454,0.007990177],"study_design_scores_gemma":[0.00021691405,0.00020426877,0.000024740872,0.000004610468,0.0000093064955,0.000017594351,0.000106538035,0.0043285177,0.6581186,0.000005430536,0.3368736,0.00008990676],"about_ca_topic_score_codex":0.0000023435234,"about_ca_topic_score_gemma":1.0154071e-7,"teacher_disagreement_score":0.32768905,"about_ca_system_score_codex":0.00001077068,"about_ca_system_score_gemma":0.0000033342696,"threshold_uncertainty_score":0.46331775},"labels":[],"label_agreement":null},{"id":"W6893756744","doi":"10.5281/zenodo.3686311","title":"CRISPR-mediated introduction of single nucleotide changes in iPSCs","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Induced pluripotent stem cell; Nucleotide; Genome; Human genome; Protocol (science); HEK 293 cells","score_opus":0.021280979939992613,"score_gpt":0.25251503184328883,"score_spread":0.2312340519032962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6893756744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95915383,0.0005508994,0.018041931,0.007863096,0.00022637357,0.00058894686,0.00018477578,0.00030404478,0.01308613],"genre_scores_gemma":[0.9978731,0.00012736917,0.00017999204,0.00012343274,0.0003851063,2.3249553e-8,0.00093684654,0.00031754503,0.000056550158],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992935,0.00006690151,0.00013600587,0.00023817105,0.00010765354,0.00015778473],"domain_scores_gemma":[0.9995717,0.0000032157154,0.00004154524,0.00017206847,0.00013453104,0.00007694498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014948295,0.00007496394,0.00008619477,0.00006723755,0.00011774611,0.000045099438,0.00025113998,0.0000474396,0.00077657157],"category_scores_gemma":[0.00041995486,0.00008577462,0.000022489858,0.00025077796,0.000048689875,0.0000053665744,0.0002989616,0.00008180416,0.0001842527],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052066116,0.000047584082,0.000012962483,0.000043535685,0.000012303697,0.0000016572419,0.00033550235,0.00031289455,0.95405173,0.000038778533,0.03458036,0.010510628],"study_design_scores_gemma":[0.00028220785,0.00035652492,0.00044370728,0.000005548369,0.000004018037,0.000008479775,0.00019092773,0.00023446842,0.23090062,0.000004354814,0.7674828,0.00008631361],"about_ca_topic_score_codex":0.0000040395503,"about_ca_topic_score_gemma":0.0000013160353,"teacher_disagreement_score":0.73290247,"about_ca_system_score_codex":0.000015970205,"about_ca_system_score_gemma":0.0000015005137,"threshold_uncertainty_score":0.85029143},"labels":[],"label_agreement":null},{"id":"W6901476529","doi":"10.60692/1d48g-0z589","title":"Effects of CRISPR/Cas9 dosage on TICAM1 and RBL gene mutation rate, embryonic development, hatchability and fry survival in channel catfish","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Catfish; Microinjection; Embryo; Dose; Embryogenesis; Mutation; Yolk sac; Gene","score_opus":0.009366630118803685,"score_gpt":0.2299317037660267,"score_spread":0.22056507364722303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901476529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760468,0.00002397627,0.023358548,0.0000094119705,0.00015138953,0.00026281492,0.000010092455,0.000012502496,0.00012443952],"genre_scores_gemma":[0.999656,0.0000014327835,0.0001891905,0.00003224297,0.000044912234,0.000027243936,0.000022966604,0.0000066844877,0.00001928889],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993253,0.000042731775,0.00027258828,0.00014364545,0.000079854675,0.00013587592],"domain_scores_gemma":[0.99964833,0.000008137464,0.00008423824,0.00013880503,0.0000725924,0.000047865968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002868575,0.0001185383,0.00014178241,0.00008904128,0.000042684096,0.000025399146,0.000046061185,0.000097917065,7.9093246e-7],"category_scores_gemma":[0.00003445227,0.000109278815,0.000016480091,0.00006812512,0.000038074453,0.0000144238675,0.0000474437,0.000037400394,0.0000071603],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001990533,0.000092666836,0.5070509,0.017918592,0.0006003026,0.000027837605,0.30247194,0.0016243713,0.1549151,0.00020181717,0.00022618253,0.012879775],"study_design_scores_gemma":[0.0010300588,0.00016223082,0.4441871,0.00009238175,0.00001019701,0.000011352887,0.0012822318,0.00093788235,0.55206436,8.2963544e-7,0.0000677363,0.00015363898],"about_ca_topic_score_codex":0.0000062531076,"about_ca_topic_score_gemma":0.000003896007,"teacher_disagreement_score":0.39714926,"about_ca_system_score_codex":0.00001780624,"about_ca_system_score_gemma":0.000022229053,"threshold_uncertainty_score":0.44562608},"labels":[],"label_agreement":null},{"id":"W6901874714","doi":"10.6084/m9.figshare.17084288.v1","title":"Additional file 2 of Revealing the composition of the eukaryotic microbiome of oyster spat by CRISPR-Cas Selective Amplicon Sequencing (CCSAS)","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Amplicon; Oyster; Gene; Composition (language); Ribosomal RNA; Table (database); DNA sequencing; Microbiome","score_opus":0.010418414458077011,"score_gpt":0.24779926598072055,"score_spread":0.23738085152264354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901874714","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009879558,0.00036009427,0.000055189477,0.000022969505,0.000019842882,0.00010255231,0.9892913,0.0000026252642,0.00026585278],"genre_scores_gemma":[0.5592023,0.000002253829,0.00020778952,0.000060961767,0.00004633028,0.000045259298,0.44026265,0.000010418716,0.00016199212],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994775,0.000037293034,0.00017204124,0.0001356271,0.000082509025,0.00009501975],"domain_scores_gemma":[0.9993404,0.000111810434,0.000121339406,0.00020939534,0.00020122803,0.000015803165],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019181518,0.00007918111,0.000104797364,0.000012462324,0.00003630678,0.0000048906354,0.00012481472,0.00006592788,0.18516824],"category_scores_gemma":[0.00025945905,0.000059924514,0.00009607523,0.00010989072,0.000016794442,0.0000022624822,0.00009572214,0.00006344071,0.000007338536],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002668509,0.00000772049,0.0000044659696,0.00007735324,0.000020055535,2.4496867e-7,0.000027589133,0.00015825225,0.48126268,3.141122e-7,0.5184052,0.00003345052],"study_design_scores_gemma":[0.00008198191,0.00003095671,0.0015927674,0.00082417816,0.000010681064,0.000022156572,0.000057345427,0.000092560345,0.96930736,0.0000038872577,0.027909053,0.0000670541],"about_ca_topic_score_codex":0.000005680538,"about_ca_topic_score_gemma":0.000008426316,"teacher_disagreement_score":0.5493228,"about_ca_system_score_codex":0.000014684115,"about_ca_system_score_gemma":0.00008000859,"threshold_uncertainty_score":0.8155766},"labels":[],"label_agreement":null},{"id":"W6902140898","doi":"10.6084/m9.figshare.26591594.v1","title":"Additional file 1 of A unique effector secreted by Pseudozyma flocculosa mediates its biocontrol activity","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Agriculture and Agri-Food Canada","funders":"","keywords":"Mutant; Wild type; Gene; Amplicon; Effector; Coding region; Sequence analysis","score_opus":0.005930216476705234,"score_gpt":0.2567451448318357,"score_spread":0.2508149283551305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902140898","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014519374,0.0009716365,0.000020726273,0.000018823632,0.000031472428,0.00015770635,0.99697953,0.00003326888,0.00033488774],"genre_scores_gemma":[0.13035564,0.0000052466244,0.000066447144,0.00002593805,0.00018247697,0.00064082775,0.86818236,0.0000202395,0.000520809],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994303,0.000022805456,0.00009033245,0.00022106047,0.000089574896,0.00014595005],"domain_scores_gemma":[0.9994722,0.00024892937,0.000026055119,0.00013413798,0.00005501963,0.00006368057],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000015702068,0.00012324384,0.000106278654,0.00003073822,0.00001925402,0.00001811314,0.00010112715,0.0001330609,0.8865103],"category_scores_gemma":[0.0009432942,0.00011775927,0.0000946318,0.00008737329,0.000005739483,0.0000036576898,0.00005816424,0.00008181786,0.0003806759],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006932942,0.000008624123,1.8837686e-7,0.00015372336,0.00003752742,0.000002505437,0.0000035628611,0.0000094856505,0.2437784,1.9738627e-7,0.7551338,0.0008650292],"study_design_scores_gemma":[0.00007359705,0.000066228145,0.0001241625,0.000439104,0.0000045503234,0.000004738683,0.0000015183527,0.001233596,0.3490786,8.8259605e-7,0.648871,0.000102043006],"about_ca_topic_score_codex":0.0000013401212,"about_ca_topic_score_gemma":0.0000033952444,"teacher_disagreement_score":0.8861296,"about_ca_system_score_codex":0.000007789803,"about_ca_system_score_gemma":0.00006953588,"threshold_uncertainty_score":0.48929453},"labels":[],"label_agreement":null},{"id":"W6902158488","doi":"10.6084/m9.figshare.19759826","title":"Additional file 1 of Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci","year":2022,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Electroporation; Simple (philosophy); Table (database); Allele; Base sequence","score_opus":0.01855370317165542,"score_gpt":0.25732006610777236,"score_spread":0.23876636293611694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902158488","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00498799,0.00009894287,0.00061612483,0.000022026781,2.0479823e-7,0.00022975968,0.99401736,0.0000021084932,0.000025477459],"genre_scores_gemma":[0.26444814,6.3940524e-7,0.00074589014,0.000026417709,0.00012662903,0.00075248844,0.7338691,0.0000055572477,0.00002515261],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994894,0.000035863482,0.00015824978,0.0001361551,0.00009532042,0.00008499299],"domain_scores_gemma":[0.99977726,0.000013512386,0.000075227894,0.000072499715,0.000053639396,0.0000078414205],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000053520955,0.0000553451,0.0000656369,0.000032193337,0.000044303855,0.0000047071476,0.00007638802,0.000029332386,0.5691895],"category_scores_gemma":[0.00024896557,0.000057242745,0.000032625725,0.00008992373,0.00000515004,0.000003656928,0.000028372118,0.00005241424,0.0000011389507],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000885329,0.000042884425,0.0000018052198,0.000020371072,0.0000041815606,4.33548e-8,0.000022654707,0.028741026,0.25994012,0.0000027371184,0.71119833,0.000016995367],"study_design_scores_gemma":[0.00015319168,0.00011287165,0.0002463799,1.3948977e-7,0.0000013369664,0.0000015520637,0.00016677646,0.01760724,0.036589287,0.0000103212415,0.94504744,0.00006344496],"about_ca_topic_score_codex":0.000002338266,"about_ca_topic_score_gemma":0.000012735062,"teacher_disagreement_score":0.56918836,"about_ca_system_score_codex":0.000017505605,"about_ca_system_score_gemma":0.000019308238,"threshold_uncertainty_score":0.43120432},"labels":[],"label_agreement":null},{"id":"W6908791922","doi":"10.3389/fendo.2022.870905.s001","title":"Image_1_Global, Regional, and National Burden of Low Bone Mineral Density From 1990 to 2019: Results From the Global Burden of Disease Study 2019.tif","year":2022,"lang":"en","type":"other","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Burden of disease; Disease burden; Incidence (geometry); Epidemiology; Estimation; Prevalence; Population; Disease; Osteoporosis","score_opus":0.012361533699593509,"score_gpt":0.28191775863735635,"score_spread":0.2695562249377628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6908791922","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030588215,0.008949673,0.00000510647,0.00023369341,0.00010089952,0.0006342916,0.95691127,0.000017046541,0.002559828],"genre_scores_gemma":[0.23513918,0.00018955884,0.0004545182,0.00028187782,0.0026542244,0.00013344614,0.73524743,0.0001989536,0.025700798],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986612,0.000053683638,0.00025838576,0.0004923164,0.00038517118,0.00014921321],"domain_scores_gemma":[0.99903554,0.000040659153,0.00017635606,0.000513337,0.00011419738,0.000119927114],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005152237,0.00023338759,0.00025710888,0.00003101108,0.000035059096,0.000017529479,0.00034189635,0.00012568755,0.00929015],"category_scores_gemma":[0.00047674257,0.00020832609,0.00010198378,0.000089121364,0.000019883271,0.0000019123584,0.00052836,0.00008993617,0.000028110602],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019987387,0.00005268844,0.00011940088,0.000031224874,0.00016383105,0.000010057658,0.00007509427,0.00061232195,0.0014535554,5.9263306e-7,0.99714476,0.00013659644],"study_design_scores_gemma":[0.0017757717,0.00022270822,0.01952949,0.00065231905,0.00011937584,0.0000037972134,0.0002560089,0.00011969392,0.00039966727,0.000030298017,0.9763623,0.00052860036],"about_ca_topic_score_codex":0.0029351767,"about_ca_topic_score_gemma":0.00036287354,"teacher_disagreement_score":0.2216638,"about_ca_system_score_codex":0.000025169646,"about_ca_system_score_gemma":0.00012666834,"threshold_uncertainty_score":0.9916155},"labels":[],"label_agreement":null},{"id":"W6911932387","doi":"10.5281/zenodo.15305507","title":"A guide to selecting high-performing antibodies for TMEM175 (UniProt ID: Q9BSA9) for use in western blot, immunoprecipitation, and immunofluorescence","year":2025,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Immunofluorescence; Antibody; Genome; Government (linguistics); Genomics; Protocol (science)","score_opus":0.013912568958506236,"score_gpt":0.2963289084354991,"score_spread":0.28241633947699285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6911932387","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7844666,0.00042821758,0.21245623,0.00032318186,0.00011656739,0.001366468,0.00012212452,0.000103382445,0.000617202],"genre_scores_gemma":[0.98282814,0.00019023946,0.013224022,0.00015256612,0.00009251303,0.0000020262164,0.0008607971,0.00043332102,0.002216381],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990526,0.000043861477,0.00021981294,0.00033690894,0.000074570504,0.00027223726],"domain_scores_gemma":[0.99931103,0.000031137526,0.000039225415,0.00023061612,0.0003380334,0.000049960076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041201667,0.00011719902,0.00011797447,0.00017374152,0.0006131651,0.00026951497,0.00028472545,0.000058441467,0.000021806636],"category_scores_gemma":[0.00074438914,0.00013323053,0.000027285427,0.00022259112,0.000037723872,0.000021049545,0.00040163164,0.00007261954,0.000013253275],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028309846,0.00005448221,0.00021983348,0.00023627795,0.0000690496,8.790001e-7,0.00081218214,0.0007922857,0.9060225,0.00042173357,0.014591653,0.076496035],"study_design_scores_gemma":[0.0014290622,0.00054894463,0.0049999994,0.00014715435,0.000022690263,0.000021022546,0.0005337007,0.0013735854,0.1588064,0.00005720322,0.831765,0.00029523714],"about_ca_topic_score_codex":0.00005111096,"about_ca_topic_score_gemma":0.00001010419,"teacher_disagreement_score":0.81717336,"about_ca_system_score_codex":0.000037152728,"about_ca_system_score_gemma":0.0000065074946,"threshold_uncertainty_score":0.5432983},"labels":[],"label_agreement":null},{"id":"W6912486164","doi":"10.5281/zenodo.3669098","title":"Generation of Knockout Cell Lines Using CRISPR-Cas9 Technology","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cell culture; Set (abstract data type); Genome; Cell; Protocol (science)","score_opus":0.05297389630115775,"score_gpt":0.29405869083927016,"score_spread":0.2410847945381124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6912486164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82246745,0.0007738229,0.16987135,0.0006374105,0.00008910191,0.00026930196,0.000083236744,0.0001841531,0.0056241876],"genre_scores_gemma":[0.99712116,0.00008850007,0.0016414698,0.00007335333,0.00024471222,1.6291557e-8,0.00040701593,0.0003471088,0.00007665236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993045,0.000044206787,0.0001605005,0.00023983451,0.00009918629,0.00015179759],"domain_scores_gemma":[0.99942154,0.0000016233612,0.000053316213,0.00020737667,0.00024435393,0.00007176861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819455,0.00008444282,0.000087083026,0.0000752522,0.0002749443,0.000055167635,0.00031169588,0.00007900711,0.00042314833],"category_scores_gemma":[0.00018868063,0.00009438125,0.00003397552,0.00024228418,0.000056647612,0.000005361691,0.00042991142,0.00008336587,0.00012953125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000151489,0.000023993405,0.000005573675,0.00003917681,0.0000128383435,0.0000012939075,0.00012464478,0.0019370975,0.98059475,0.00007077826,0.00918454,0.007990177],"study_design_scores_gemma":[0.00021691405,0.00020426877,0.000024740872,0.000004610468,0.0000093064955,0.000017594351,0.000106538035,0.0043285177,0.6581186,0.000005430536,0.3368736,0.00008990676],"about_ca_topic_score_codex":0.0000023435234,"about_ca_topic_score_gemma":1.0154071e-7,"teacher_disagreement_score":0.32768905,"about_ca_system_score_codex":0.00001077068,"about_ca_system_score_gemma":0.0000033342696,"threshold_uncertainty_score":0.46331775},"labels":[],"label_agreement":null},{"id":"W6920232445","doi":"10.60692/anytt-j2722","title":"Application of CRISPR/Cas9 Genome Editing Technology for the Improvement of Crops Cultivated in Tropical Climates: Recent Progress, Prospects, and Challenges","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada)","funders":"","keywords":"Genome editing; CRISPR; Population; Zinc finger nuclease; Genome; Food security; Transcription activator-like effector nuclease; Emerging technologies","score_opus":0.015653376067890096,"score_gpt":0.25579390583022854,"score_spread":0.24014052976233843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920232445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9022672,0.0006393946,0.095492944,0.00022341039,0.00008836195,0.00116212,0.00004554709,0.0000225733,0.000058442452],"genre_scores_gemma":[0.99901074,0.00004109465,0.0006287267,0.0000065169515,0.000073894895,0.00021728051,0.000014458984,0.0000055800683,0.0000016851205],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935555,0.0000060066427,0.0003512831,0.000103823026,0.0000645449,0.00011875878],"domain_scores_gemma":[0.9994331,0.0000023686218,0.0001733704,0.00018489675,0.00019108909,0.000015180571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013476814,0.00007956758,0.000116882846,0.000069306196,0.00003306355,0.0000086535365,0.000084096355,0.00009217591,4.781392e-7],"category_scores_gemma":[0.00002020563,0.000057410376,0.000019405607,0.00008198021,0.00007493929,0.0000063496304,0.00005366192,0.000027985747,9.641471e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091621693,0.000066463595,0.6437522,0.011016361,0.0004327247,5.3358394e-7,0.052309074,0.0005015796,0.16339347,0.003054042,0.000042007512,0.12451529],"study_design_scores_gemma":[0.0016531729,0.0007798214,0.13114521,0.00014039436,0.000030920546,0.000011456173,0.015028636,0.005757124,0.84125555,0.000005236657,0.004007442,0.00018504336],"about_ca_topic_score_codex":0.0000012845137,"about_ca_topic_score_gemma":0.0000010624077,"teacher_disagreement_score":0.6778621,"about_ca_system_score_codex":0.0000133666845,"about_ca_system_score_gemma":0.000009489514,"threshold_uncertainty_score":0.23411272},"labels":[],"label_agreement":null},{"id":"W6920480710","doi":"10.60692/k4azn-ng974","title":"Application of CRISPR/Cas9 Genome Editing Technology for the Improvement of Crops Cultivated in Tropical Climates: Recent Progress, Prospects, and Challenges","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada)","funders":"","keywords":"Genome editing; CRISPR; Population; Zinc finger nuclease; Genome; Food security; Transcription activator-like effector nuclease; Emerging technologies","score_opus":0.015653376067890096,"score_gpt":0.25579390583022854,"score_spread":0.24014052976233843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920480710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9022672,0.0006393946,0.095492944,0.00022341039,0.00008836195,0.00116212,0.00004554709,0.0000225733,0.000058442452],"genre_scores_gemma":[0.99901074,0.00004109465,0.0006287267,0.0000065169515,0.000073894895,0.00021728051,0.000014458984,0.0000055800683,0.0000016851205],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935555,0.0000060066427,0.0003512831,0.000103823026,0.0000645449,0.00011875878],"domain_scores_gemma":[0.9994331,0.0000023686218,0.0001733704,0.00018489675,0.00019108909,0.000015180571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013476814,0.00007956758,0.000116882846,0.000069306196,0.00003306355,0.0000086535365,0.000084096355,0.00009217591,4.781392e-7],"category_scores_gemma":[0.00002020563,0.000057410376,0.000019405607,0.00008198021,0.00007493929,0.0000063496304,0.00005366192,0.000027985747,9.641471e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091621693,0.000066463595,0.6437522,0.011016361,0.0004327247,5.3358394e-7,0.052309074,0.0005015796,0.16339347,0.003054042,0.000042007512,0.12451529],"study_design_scores_gemma":[0.0016531729,0.0007798214,0.13114521,0.00014039436,0.000030920546,0.000011456173,0.015028636,0.005757124,0.84125555,0.000005236657,0.004007442,0.00018504336],"about_ca_topic_score_codex":0.0000012845137,"about_ca_topic_score_gemma":0.0000010624077,"teacher_disagreement_score":0.6778621,"about_ca_system_score_codex":0.0000133666845,"about_ca_system_score_gemma":0.000009489514,"threshold_uncertainty_score":0.23411272},"labels":[],"label_agreement":null},{"id":"W6920607801","doi":"10.6084/m9.figshare.24076986.v1","title":"Additional file 1 of CRISPR/Cas9 mediated gene editing of transcription factor ACE1 for enhanced cellulase production in thermophilic fungus Rasamsonia emersonii","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Cellulase; Thermophile; Fungus; Mutant; Gene; Table (database); Transcription factor; Transcription (linguistics)","score_opus":0.020433610081273607,"score_gpt":0.27367519528208206,"score_spread":0.25324158520080847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920607801","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.042248722,0.00012210148,0.000050312115,0.000018313798,0.00007738517,0.0002750775,0.9571545,0.00001760824,0.0000359585],"genre_scores_gemma":[0.41591474,0.0000062388012,0.00014047009,0.0000047943336,0.00021246672,0.00042650852,0.5831233,0.000015215444,0.00015621418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992902,0.000014753036,0.00020543503,0.00022135193,0.00010148119,0.00016673034],"domain_scores_gemma":[0.999546,0.00008786988,0.00009157851,0.0001316132,0.000111284346,0.000031653257],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000028040282,0.000104381994,0.00012326153,0.00007466749,0.000022632497,0.0000033034075,0.00008024728,0.000106933796,0.34029987],"category_scores_gemma":[0.0013165736,0.00011314287,0.000083786595,0.00017281817,0.000007365544,0.0000046968403,0.000021046033,0.000050289076,0.000037094345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017129532,0.000013641071,6.8772226e-7,0.00013439992,0.000010471701,3.5485812e-7,0.000062941304,0.00028569938,0.58151925,3.2695205e-8,0.4171129,0.0008424904],"study_design_scores_gemma":[0.00024962868,0.00008982175,0.0015764164,0.00032786417,0.0000040484288,0.0000011301887,0.00008572234,0.0004568479,0.9453037,0.0000027312324,0.051795404,0.00010669073],"about_ca_topic_score_codex":0.000001660782,"about_ca_topic_score_gemma":0.000017696748,"teacher_disagreement_score":0.3740312,"about_ca_system_score_codex":0.000009279459,"about_ca_system_score_gemma":0.00004313266,"threshold_uncertainty_score":0.6603032},"labels":[],"label_agreement":null},{"id":"W6920689744","doi":"10.6084/m9.figshare.13250775","title":"Additional file 1 of A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Drosophila (subgenus); RNA; Drosophila melanogaster; Key (lock); Base sequence","score_opus":0.02921508852160704,"score_gpt":0.27915616420304196,"score_spread":0.24994107568143492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920689744","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027813148,0.00003588988,0.000110527224,0.00005943873,0.000008138476,0.00014487913,0.99889207,0.000007013336,0.0004639316],"genre_scores_gemma":[0.16882263,2.064066e-7,0.0009773225,0.00014817207,0.00013008143,0.00035687574,0.8295034,0.000011257937,0.00005004283],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995942,0.0000051967004,0.000109186934,0.00014392831,0.000057029672,0.000090467045],"domain_scores_gemma":[0.99972326,0.00007734497,0.000036598132,0.000081068516,0.000045729048,0.000035997145],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000068013815,0.00006690015,0.00006955377,0.000018359198,0.000012623625,0.000004928971,0.00006921482,0.00006538894,0.73427665],"category_scores_gemma":[0.00094802625,0.00007715178,0.000058250305,0.000055599998,0.0000026210753,0.0000019903573,0.000024358347,0.00003123704,0.000054915297],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002326246,0.000009844029,0.0000026013197,0.000086187116,0.000004599678,7.186748e-7,0.00000984555,0.0022425407,0.008368872,7.5247783e-7,0.98894906,0.00030173088],"study_design_scores_gemma":[0.000363619,0.00013837742,0.001794444,0.00022352216,0.0000026708506,5.5013146e-7,0.00001173641,0.011623543,0.056782804,0.0000070273,0.9289331,0.0001185986],"about_ca_topic_score_codex":6.489753e-7,"about_ca_topic_score_gemma":0.0000037907948,"teacher_disagreement_score":0.7342217,"about_ca_system_score_codex":0.0000053651365,"about_ca_system_score_gemma":0.00004456664,"threshold_uncertainty_score":0.31461585},"labels":[],"label_agreement":null},{"id":"W6920745739","doi":"10.6084/m9.figshare.14167687.v1","title":"Additional file 1 of STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Exon; Gene; Transfection; RNA splicing; Stop codon; Cell cycle; Plasmid; Cell culture","score_opus":0.0064956029972011,"score_gpt":0.2337810532830489,"score_spread":0.22728545028584782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920745739","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020093461,0.00166087,0.000004005351,0.000110062414,0.0000049255787,0.0004905209,0.9772382,0.0000025213178,0.00039544798],"genre_scores_gemma":[0.62442523,0.00003482799,0.00022483579,0.000151364,0.00004964726,0.0012376743,0.37297657,0.000014063871,0.0008857937],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948066,0.000036423404,0.00012570861,0.00015714591,0.00008868323,0.00011137077],"domain_scores_gemma":[0.99959457,0.00016267462,0.000043927037,0.00012953537,0.000045143144,0.000024137367],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000036184145,0.00009451671,0.00012441441,0.000009834836,0.00004336948,0.000022467317,0.00007120559,0.000068991554,0.1235897],"category_scores_gemma":[0.00016714154,0.000057180623,0.000044710774,0.00004206671,0.000022797061,0.0000027295866,0.000043481792,0.00005918604,0.0000035761475],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007630131,0.000034755703,8.120107e-7,0.0001137055,0.000012668541,0.0000037224252,0.00015458731,0.0000073051633,0.1604262,3.0797838e-7,0.8380136,0.001156075],"study_design_scores_gemma":[0.0020301256,0.00006637144,0.0002679121,0.00048490602,0.0000051347206,0.00000801743,0.0001578884,0.00035458987,0.8339366,0.00001018756,0.16257997,0.00009830463],"about_ca_topic_score_codex":0.0000031777897,"about_ca_topic_score_gemma":0.0000155412,"teacher_disagreement_score":0.6754336,"about_ca_system_score_codex":0.0000019547128,"about_ca_system_score_gemma":0.000044420583,"threshold_uncertainty_score":0.87721145},"labels":[],"label_agreement":null},{"id":"W6920749312","doi":"10.6084/m9.figshare.19759826.v1","title":"Additional file 1 of Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci","year":2022,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Electroporation; Simple (philosophy); Table (database); Allele; Base sequence","score_opus":0.01855370317165542,"score_gpt":0.25732006610777236,"score_spread":0.23876636293611694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920749312","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00498799,0.00009894287,0.00061612483,0.000022026781,2.0479823e-7,0.00022975968,0.99401736,0.0000021084932,0.000025477459],"genre_scores_gemma":[0.26444814,6.3940524e-7,0.00074589014,0.000026417709,0.00012662903,0.00075248844,0.7338691,0.0000055572477,0.00002515261],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994894,0.000035863482,0.00015824978,0.0001361551,0.00009532042,0.00008499299],"domain_scores_gemma":[0.99977726,0.000013512386,0.000075227894,0.000072499715,0.000053639396,0.0000078414205],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000053520955,0.0000553451,0.0000656369,0.000032193337,0.000044303855,0.0000047071476,0.00007638802,0.000029332386,0.5691895],"category_scores_gemma":[0.00024896557,0.000057242745,0.000032625725,0.00008992373,0.00000515004,0.000003656928,0.000028372118,0.00005241424,0.0000011389507],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000885329,0.000042884425,0.0000018052198,0.000020371072,0.0000041815606,4.33548e-8,0.000022654707,0.028741026,0.25994012,0.0000027371184,0.71119833,0.000016995367],"study_design_scores_gemma":[0.00015319168,0.00011287165,0.0002463799,1.3948977e-7,0.0000013369664,0.0000015520637,0.00016677646,0.01760724,0.036589287,0.0000103212415,0.94504744,0.00006344496],"about_ca_topic_score_codex":0.000002338266,"about_ca_topic_score_gemma":0.000012735062,"teacher_disagreement_score":0.56918836,"about_ca_system_score_codex":0.000017505605,"about_ca_system_score_gemma":0.000019308238,"threshold_uncertainty_score":0.43120432},"labels":[],"label_agreement":null},{"id":"W6920849579","doi":"10.6084/m9.figshare.24076986","title":"Additional file 1 of CRISPR/Cas9 mediated gene editing of transcription factor ACE1 for enhanced cellulase production in thermophilic fungus Rasamsonia emersonii","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Cellulase; Thermophile; Fungus; Mutant; Gene; Table (database); Transcription factor; Transcription (linguistics)","score_opus":0.020433610081273607,"score_gpt":0.27367519528208206,"score_spread":0.25324158520080847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920849579","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.042248722,0.00012210148,0.000050312115,0.000018313798,0.00007738517,0.0002750775,0.9571545,0.00001760824,0.0000359585],"genre_scores_gemma":[0.41591474,0.0000062388012,0.00014047009,0.0000047943336,0.00021246672,0.00042650852,0.5831233,0.000015215444,0.00015621418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992902,0.000014753036,0.00020543503,0.00022135193,0.00010148119,0.00016673034],"domain_scores_gemma":[0.999546,0.00008786988,0.00009157851,0.0001316132,0.000111284346,0.000031653257],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000028040282,0.000104381994,0.00012326153,0.00007466749,0.000022632497,0.0000033034075,0.00008024728,0.000106933796,0.34029987],"category_scores_gemma":[0.0013165736,0.00011314287,0.000083786595,0.00017281817,0.000007365544,0.0000046968403,0.000021046033,0.000050289076,0.000037094345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017129532,0.000013641071,6.8772226e-7,0.00013439992,0.000010471701,3.5485812e-7,0.000062941304,0.00028569938,0.58151925,3.2695205e-8,0.4171129,0.0008424904],"study_design_scores_gemma":[0.00024962868,0.00008982175,0.0015764164,0.00032786417,0.0000040484288,0.0000011301887,0.00008572234,0.0004568479,0.9453037,0.0000027312324,0.051795404,0.00010669073],"about_ca_topic_score_codex":0.000001660782,"about_ca_topic_score_gemma":0.000017696748,"teacher_disagreement_score":0.3740312,"about_ca_system_score_codex":0.000009279459,"about_ca_system_score_gemma":0.00004313266,"threshold_uncertainty_score":0.6603032},"labels":[],"label_agreement":null},{"id":"W6920881994","doi":"10.6084/m9.figshare.28975055","title":"Additional file 1 of Predicting adenine base editing efficiencies in different cellular contexts by deep learning","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"","keywords":"Deep learning; Base (topology); File format; Focus (optics); Key (lock)","score_opus":0.004653377892996529,"score_gpt":0.23025878211324435,"score_spread":0.22560540422024783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920881994","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009310883,0.00077456445,0.000120162775,0.000007914387,0.00003279143,0.000087374356,0.9886599,0.000014135155,0.0009922661],"genre_scores_gemma":[0.3748938,0.0000010301843,0.000075174816,0.000022564922,0.00012354628,0.00015162122,0.62418276,0.000007389347,0.0005421002],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994192,0.000018135732,0.00015671899,0.0001748006,0.000080406695,0.00015072475],"domain_scores_gemma":[0.9995911,0.00018556797,0.00005213661,0.00008916345,0.000054117067,0.00002791131],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000017886168,0.000096691045,0.000101177764,0.000042179698,0.00003776595,0.000009034687,0.00009358884,0.00007454235,0.5125082],"category_scores_gemma":[0.0029526697,0.000097473356,0.00004847254,0.000080378435,0.0000070650713,0.0000018592561,0.0000962374,0.00010542236,0.00001351986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003781521,0.000019856097,0.00009384311,0.00007629112,0.0000088249635,0.0000013980647,0.000019560312,0.0010400881,0.04962533,1.7761424e-7,0.9481953,0.00091556786],"study_design_scores_gemma":[0.00036351645,0.00009654711,0.0041574915,0.002169473,0.000005558838,0.0000017486798,0.00023791983,0.01046491,0.34455898,0.000001676665,0.6377562,0.00018593101],"about_ca_topic_score_codex":0.0000013449885,"about_ca_topic_score_gemma":0.000007666846,"teacher_disagreement_score":0.5124947,"about_ca_system_score_codex":0.000009248453,"about_ca_system_score_gemma":0.000021562584,"threshold_uncertainty_score":0.48793742},"labels":[],"label_agreement":null},{"id":"W6920889787","doi":"10.6084/m9.figshare.16614647","title":"Additional file 3 of Development of a Csy4-processed guide RNA delivery system with soybean-infecting virus ALSV for genome editing","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Sanger sequencing; Genome; Genome editing; RNA; Gene; DNA sequencing; Raw data; Genomics","score_opus":0.011987280997346453,"score_gpt":0.248599405021447,"score_spread":0.23661212402410056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920889787","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028309342,0.00027393072,0.00091648404,0.0000015304579,0.000016157772,0.000121373756,0.9948919,0.0000120434015,0.0009356661],"genre_scores_gemma":[0.121324524,7.1323893e-7,0.016050654,0.000015067163,0.0002362303,0.00045246317,0.8617104,0.000023613098,0.00018628512],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993386,0.00000665207,0.00022548951,0.00018785038,0.000099145494,0.00014220791],"domain_scores_gemma":[0.99922615,0.00010702327,0.00012968344,0.00011931886,0.000381254,0.000036566056],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000025006448,0.00009964512,0.00013108902,0.000022990807,0.00004988135,0.000008973236,0.000078013465,0.00006365521,0.19548455],"category_scores_gemma":[0.0006612927,0.00010079422,0.000055828255,0.00006863193,0.00000403084,0.0000031938303,0.00006732953,0.00003269801,0.000010570932],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000114258155,0.000024612122,0.0000019032356,0.0013802525,0.00010208015,0.0000045293023,0.00006789041,0.00068703055,0.32803044,5.235461e-7,0.66821027,0.0014790755],"study_design_scores_gemma":[0.0001707729,0.00004389344,0.0002210444,0.0014431457,0.0000063005086,0.000012324161,0.00021682677,0.00021190931,0.6393731,1.817364e-7,0.35818604,0.00011442159],"about_ca_topic_score_codex":0.0000010450045,"about_ca_topic_score_gemma":0.00002160326,"teacher_disagreement_score":0.31134272,"about_ca_system_score_codex":0.000015153757,"about_ca_system_score_gemma":0.0003131972,"threshold_uncertainty_score":0.8052509},"labels":[],"label_agreement":null},{"id":"W6920913615","doi":"10.6084/m9.figshare.12421364.v1","title":"Additional file 1 of MAUDE: inferring expression changes in sorting-based CRISPR screens","year":2020,"lang":"en","type":"article","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Expression (computer science); Gene expression; Key (lock); DNA","score_opus":0.02580801185670193,"score_gpt":0.3153792072701039,"score_spread":0.2895711954134019,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920913615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.52137876,0.0004901896,0.015498864,0.0015730859,0.00016008783,0.001726649,0.42651588,0.000011430714,0.032645058],"genre_scores_gemma":[0.9422066,0.000004707163,0.028327182,0.00022073842,0.00015772319,0.00010446195,0.028635286,0.00002063116,0.00032262554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995064,0.000012402965,0.000121509576,0.00018535522,0.00006545354,0.000108849286],"domain_scores_gemma":[0.9997352,0.000034875135,0.000047929065,0.000108218694,0.000022249282,0.00005152588],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003454851,0.00007236666,0.00009245592,0.000020820586,0.000016193182,0.000012029491,0.00015955193,0.00005758074,0.20412385],"category_scores_gemma":[0.00022797543,0.00007491802,0.000025754309,0.000058675654,0.000015771473,0.0000023086475,0.00014478658,0.00004645855,0.000019208695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005136686,0.00003361682,0.0001928739,0.000018706553,0.00000755786,0.000004492287,0.000077397504,0.0026568864,0.6498938,2.6037864e-7,0.33789942,0.009163586],"study_design_scores_gemma":[0.00020483347,0.000084202205,0.0009623382,0.00008432363,0.000002015472,6.123827e-7,0.00006453245,0.0010275723,0.68323874,7.31055e-7,0.3142444,0.00008570119],"about_ca_topic_score_codex":0.000006766438,"about_ca_topic_score_gemma":0.00010748814,"teacher_disagreement_score":0.4208279,"about_ca_system_score_codex":0.0000029959133,"about_ca_system_score_gemma":0.000043654658,"threshold_uncertainty_score":0.7966037},"labels":[],"label_agreement":null},{"id":"W6920985788","doi":"10.6084/m9.figshare.26591594","title":"Additional file 1 of A unique effector secreted by Pseudozyma flocculosa mediates its biocontrol activity","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Agriculture and Agri-Food Canada","funders":"","keywords":"Mutant; Wild type; Gene; Amplicon; Effector; Coding region; Sequence analysis","score_opus":0.005930216476705234,"score_gpt":0.2567451448318357,"score_spread":0.2508149283551305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920985788","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014519374,0.0009716365,0.000020726273,0.000018823632,0.000031472428,0.00015770635,0.99697953,0.00003326888,0.00033488774],"genre_scores_gemma":[0.13035564,0.0000052466244,0.000066447144,0.00002593805,0.00018247697,0.00064082775,0.86818236,0.0000202395,0.000520809],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994303,0.000022805456,0.00009033245,0.00022106047,0.000089574896,0.00014595005],"domain_scores_gemma":[0.9994722,0.00024892937,0.000026055119,0.00013413798,0.00005501963,0.00006368057],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000015702068,0.00012324384,0.000106278654,0.00003073822,0.00001925402,0.00001811314,0.00010112715,0.0001330609,0.8865103],"category_scores_gemma":[0.0009432942,0.00011775927,0.0000946318,0.00008737329,0.000005739483,0.0000036576898,0.00005816424,0.00008181786,0.0003806759],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006932942,0.000008624123,1.8837686e-7,0.00015372336,0.00003752742,0.000002505437,0.0000035628611,0.0000094856505,0.2437784,1.9738627e-7,0.7551338,0.0008650292],"study_design_scores_gemma":[0.00007359705,0.000066228145,0.0001241625,0.000439104,0.0000045503234,0.000004738683,0.0000015183527,0.001233596,0.3490786,8.8259605e-7,0.648871,0.000102043006],"about_ca_topic_score_codex":0.0000013401212,"about_ca_topic_score_gemma":0.0000033952444,"teacher_disagreement_score":0.8861296,"about_ca_system_score_codex":0.000007789803,"about_ca_system_score_gemma":0.00006953588,"threshold_uncertainty_score":0.48929453},"labels":[],"label_agreement":null},{"id":"W6920999636","doi":"10.6084/m9.figshare.17084309","title":"Additional file 6 of Revealing the composition of the eukaryotic microbiome of oyster spat by CRISPR-Cas Selective Amplicon Sequencing (CCSAS)","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Amplicon; 18S ribosomal RNA; Gene; Primer (cosmetics); Ribosomal RNA; DNA sequencing; Sequence analysis; Oligonucleotide","score_opus":0.010599809738456253,"score_gpt":0.24805160871174717,"score_spread":0.2374517989732909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920999636","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009962362,0.00035897575,0.000056975605,0.000023106955,0.000019779436,0.00010306786,0.9892088,0.0000026299206,0.00026427774],"genre_scores_gemma":[0.56720954,0.0000022192878,0.00020921366,0.00006081076,0.00004562363,0.000045176006,0.43225634,0.000010396411,0.0001606646],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994773,0.00003729752,0.000172097,0.0001356967,0.000082543615,0.000095061994],"domain_scores_gemma":[0.99933964,0.00011243724,0.000121218014,0.00020954439,0.00020132592,0.0000158071],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019294097,0.000079207144,0.00010482233,0.000012470651,0.000036313962,0.0000048928127,0.00012485748,0.00006592741,0.18079248],"category_scores_gemma":[0.00025987433,0.00005994246,0.00009609893,0.00010995699,0.000016799579,0.0000022631586,0.0000957128,0.00006345169,0.0000073132333],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002697638,0.000007762606,0.0000045930874,0.00007743633,0.000020055362,2.4248087e-7,0.00002767637,0.0001554092,0.48419973,3.206478e-7,0.515471,0.00003308314],"study_design_scores_gemma":[0.00008211847,0.000030978692,0.0016272061,0.0008330768,0.000010693813,0.000022093724,0.000057845005,0.00009233453,0.97061485,0.00000390147,0.026557744,0.0000671475],"about_ca_topic_score_codex":0.000005742808,"about_ca_topic_score_gemma":0.000008630902,"teacher_disagreement_score":0.55724716,"about_ca_system_score_codex":0.000014667072,"about_ca_system_score_gemma":0.0000801944,"threshold_uncertainty_score":0.81995636},"labels":[],"label_agreement":null},{"id":"W6921001050","doi":"10.6084/m9.figshare.28106316","title":"Additional file 1 of A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440","year":2024,"lang":"en","type":"article","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Pseudomonas putida; Genome editing; Genome; CRISPR; DNA","score_opus":0.018042692965373454,"score_gpt":0.2938508741025612,"score_spread":0.27580818113718775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6921001050","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05892677,0.0031154235,0.023520187,0.0002445613,0.0008894519,0.0025824418,0.8845396,0.000016425629,0.026165165],"genre_scores_gemma":[0.87965095,0.000005469603,0.045315385,0.000044740464,0.00072425406,0.00093193393,0.07083902,0.00006370428,0.0024245437],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989959,0.00002649565,0.00027599357,0.00037775983,0.00009905116,0.00022477478],"domain_scores_gemma":[0.9994287,0.00020836665,0.000057873287,0.00017331015,0.000076576835,0.000055167522],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013942177,0.00015139312,0.00018439381,0.00007667736,0.000044827226,0.000095680996,0.0002034443,0.0001039889,0.043222737],"category_scores_gemma":[0.00013701903,0.00015452564,0.00009413491,0.00012557156,0.000033457953,0.000010760702,0.00008242911,0.00007158447,0.000042955464],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014648694,0.0001358978,0.000011774085,0.00045327385,0.00013346618,0.000041393316,0.00024146913,0.0049675624,0.53594124,0.000019969839,0.43973988,0.018167587],"study_design_scores_gemma":[0.00037359685,0.00023157,0.000027896596,0.00050509727,0.000015299269,0.000022697868,0.00028339983,0.005153941,0.27444845,0.000004975199,0.7187495,0.0001835482],"about_ca_topic_score_codex":0.000007696609,"about_ca_topic_score_gemma":0.000031722157,"teacher_disagreement_score":0.8207242,"about_ca_system_score_codex":0.00003587896,"about_ca_system_score_gemma":0.00015439761,"threshold_uncertainty_score":0.9576519},"labels":[],"label_agreement":null},{"id":"W6925882703","doi":"10.18739/a2g15td1j","title":"Radium and radon in massive ice, groundwater, seawater, and sediments in the Northwest Territories, Canada, 2019","year":2024,"lang":"en","type":"dataset","venue":"California Digital Library","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Dalhousie University; Natural Resources Canada; Université du Québec à Rimouski","funders":"","keywords":"Radon; Radium; Permafrost; Isotopic signature; Arctic; Isotope; Radiometric dating; Radionuclide","score_opus":0.002736554993958067,"score_gpt":0.20398928873906913,"score_spread":0.20125273374511107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6925882703","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04012585,0.0053441417,0.0000013558504,0.00033117575,0.00029734196,0.000204618,0.9536442,0.000006002377,0.000045289158],"genre_scores_gemma":[0.026871474,0.0008721972,0.000008975642,0.0003521396,0.0003288514,0.00002614801,0.97135276,0.000030631207,0.00015682119],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989666,0.000021933323,0.00023248445,0.00039177953,0.000126188,0.00026102402],"domain_scores_gemma":[0.99960196,0.000019068228,0.000031318916,0.00025885843,0.000004622689,0.00008416911],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004045865,0.00027266244,0.00019363248,0.00007361686,0.000023596167,0.00027519412,0.00022028499,0.00019513146,0.000006696822],"category_scores_gemma":[0.000009248127,0.00020661361,0.00002830155,0.00008823326,0.00005696926,0.000018220313,0.00029708003,0.00023844764,0.000012997432],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025553403,0.000025989852,0.0046372605,0.00017249421,0.000025591135,0.00017174672,0.000010560851,0.0000058102055,0.00003561455,5.8886934e-7,0.99459547,0.0002932943],"study_design_scores_gemma":[0.0002695257,0.000059094033,0.0014092125,0.000069670255,0.000014533228,0.00004454965,0.000039687187,0.000007032496,0.00035446903,0.000018401457,0.9974585,0.0002552805],"about_ca_topic_score_codex":0.028152565,"about_ca_topic_score_gemma":0.080476455,"teacher_disagreement_score":0.05232389,"about_ca_system_score_codex":0.000018607041,"about_ca_system_score_gemma":0.0001705993,"threshold_uncertainty_score":0.97831905},"labels":[],"label_agreement":null},{"id":"W6929020252","doi":"10.3897/bdj.10.e76050.suppl20","title":"Supplementary material 20 from: Simon ADF, Adamczyk EM, Basman A, Chu JWF, Gartner HN, Fletcher K, Gibbs CJ, Gibbs DM, Gilmore SR, Harbo RM, Harris LH, Humphrey E, Lamb A, Lambert P, McDaniel N, Scott J, Starzomski BM (2022) Toward an atlas of Salish Sea biodiversity: the flora and fauna of Galiano Island, British Columbia, Canada. Part I. Marine zoology. Biodiversity Data Journal 10: e76050. https://doi.org/10.3897/BDJ.10.e76050","year":2022,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Gibbs phenomenon; Calculus (dental); Mixing (physics)","score_opus":0.017868073394765312,"score_gpt":0.228984721498491,"score_spread":0.21111664810372568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929020252","genre_codex":"empirical","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7213196,0.0018765712,0.000112582085,0.0012779615,0.0015742854,0.0023601318,0.22550528,0.00024735613,0.045726243],"genre_scores_gemma":[0.06851682,0.0056532724,0.00055062375,0.0006947242,0.0023858065,0.0000013721082,0.50987107,0.0028128645,0.40951347],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968254,0.00048354222,0.0005167213,0.00093143404,0.0006753914,0.0005675171],"domain_scores_gemma":[0.99776995,0.000014878067,0.00039576745,0.0011324473,0.000381665,0.00030526644],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00060264405,0.00037440378,0.00050997385,0.00013934317,0.0008761369,0.00048742685,0.0018707115,0.000279176,0.44943568],"category_scores_gemma":[0.00015428866,0.0004644117,0.00010360558,0.00026340623,0.00034299688,0.00004079253,0.0046664537,0.0005212995,0.00020756935],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029816257,0.0001184819,0.0021874015,0.0001498391,0.00047558697,0.00009647881,0.0001277552,0.000011740685,0.0034959128,5.473817e-7,0.99165696,0.0013811056],"study_design_scores_gemma":[0.001300512,0.00047369237,0.0026450302,0.000046908215,0.00020142621,0.000033628618,0.0008034363,0.000040734118,0.0013145809,0.0000020061882,0.99266803,0.00047001767],"about_ca_topic_score_codex":0.15766758,"about_ca_topic_score_gemma":0.10185723,"teacher_disagreement_score":0.65280277,"about_ca_system_score_codex":0.00012126261,"about_ca_system_score_gemma":0.000084144405,"threshold_uncertainty_score":0.9997808},"labels":[],"label_agreement":null},{"id":"W6929105543","doi":"10.3932/ethz-a-000165966","title":"Vancouver, B.C, Canada, The Sunken Gardens Queen Elizabeth Park = Little Mountain","year":2010,"lang":"en","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Queen (butterfly); Period (music); Key (lock)","score_opus":0.0026716316292199446,"score_gpt":0.2320153703804258,"score_spread":0.22934373875120587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929105543","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003912718,0.0027005293,0.0022895695,0.00023022418,0.0028165209,0.00038488852,0.00017086598,0.000058189624,0.9909579],"genre_scores_gemma":[0.0045689405,0.00036560607,0.0004754035,0.00042255945,0.0011188198,0.000018663759,0.0001404579,0.00025498294,0.9926346],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99906695,0.00002164692,0.0001350112,0.0003211392,0.00016174909,0.00029351795],"domain_scores_gemma":[0.9991758,0.000010330606,0.000054201984,0.00064537465,0.00002729617,0.00008698903],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000076215394,0.0002551142,0.00017262113,0.000023239794,0.00004208908,0.000017374061,0.00033346767,0.00036360015,0.0016289332],"category_scores_gemma":[0.000029050796,0.0001825377,0.00007311513,0.000028314831,0.000043559485,2.2026616e-7,0.00011031507,0.00022998595,0.000015249113],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002842308,0.00000625496,0.000067721856,0.000017763216,0.00006820014,0.0000026314756,0.000004762338,0.000028222954,0.0027234126,0.000017790351,0.9967976,0.00026280375],"study_design_scores_gemma":[0.0001303706,0.000021449121,0.0000648004,0.0000123724185,0.000024085506,0.0000027870838,0.000031078143,0.000011660028,0.008689297,0.000009702492,0.9907368,0.000265628],"about_ca_topic_score_codex":0.2867247,"about_ca_topic_score_gemma":0.9681885,"teacher_disagreement_score":0.68146384,"about_ca_system_score_codex":0.000018111936,"about_ca_system_score_gemma":0.00028531533,"threshold_uncertainty_score":0.99928373},"labels":[],"label_agreement":null},{"id":"W6929561173","doi":"10.5281/zenodo.10123374","title":"Fig. 45 in A revision of Scipopus Enderlein including the subgenera Scipopus s. str., Phaeopterina Frey and Parascipopus subgen. nov. (Diptera, Micropezidae, Taeniapterinae)","year":2023,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Spermatheca; Subgenus; Dorsum; Head (geology); Male genitalia","score_opus":0.02643658677045995,"score_gpt":0.2910430166156728,"score_spread":0.2646064298452128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929561173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8040612,0.025605012,0.0073149055,0.0008728618,0.0016205118,0.004219831,0.0018831755,0.0015748554,0.15284769],"genre_scores_gemma":[0.9673975,0.0064727957,0.0006187167,0.00005571636,0.0004478785,3.6227848e-7,0.0011123066,0.0057221744,0.018172536],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981375,0.00019225456,0.0003724148,0.0006280969,0.0002705016,0.00039925065],"domain_scores_gemma":[0.99893063,0.000010037203,0.00017307671,0.00066751166,0.00010215687,0.0001165577],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005698874,0.00029378152,0.00029368995,0.00032524116,0.00039780771,0.00019743985,0.0007948376,0.00021424041,0.0008017475],"category_scores_gemma":[0.00025358834,0.00027297356,0.000076097254,0.00039359357,0.00019301935,0.000010361895,0.0016203957,0.00026196003,0.00019469696],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002494093,0.00014670128,0.00014232687,0.00067672186,0.00024704836,0.000058775393,0.0009176649,0.00017802414,0.12891455,0.00020814504,0.30196008,0.5663006],"study_design_scores_gemma":[0.00048195326,0.0002861132,0.0002935317,0.00022316817,0.000020430125,0.00006973445,0.00008701992,0.000066443965,0.0065046777,0.0000037492498,0.99167705,0.00028615497],"about_ca_topic_score_codex":0.00022500366,"about_ca_topic_score_gemma":0.00005933426,"teacher_disagreement_score":0.68971694,"about_ca_system_score_codex":0.0000491871,"about_ca_system_score_gemma":0.0000073642386,"threshold_uncertainty_score":0.9999722},"labels":[],"label_agreement":null},{"id":"W6929898344","doi":"10.5061/dryad.21364/5","title":"Newick file - BOLD neighbour-joining tree (K2P) for all 27,269 COI sequences &gt;500 bp from spiders collected in Canada","year":2015,"lang":"en","type":"other","venue":"DRYAD","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Tree (set theory); Phylogenetic tree; Biodiversity; DNA barcoding; Taxonomy (biology)","score_opus":0.010961361054958964,"score_gpt":0.26089469717065417,"score_spread":0.2499333361156952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929898344","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.045398805,0.0566203,0.0053778747,0.0011870085,0.00828506,0.004632509,0.03938443,0.00032450666,0.8387895],"genre_scores_gemma":[0.09577516,0.0015591652,0.014908914,0.003180866,0.0044974284,0.0005508723,0.04344614,0.0017157148,0.8343657],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986362,0.000027497856,0.00026395483,0.0004882112,0.00016540577,0.00041876783],"domain_scores_gemma":[0.99929035,0.000039033628,0.00011983901,0.00035631933,0.000042548803,0.00015192105],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000069202724,0.00031248885,0.00037403876,0.000084118234,0.000022866634,0.000023323997,0.000267014,0.00032911162,0.00095208426],"category_scores_gemma":[0.00010994503,0.00033878107,0.00007294278,0.00011497986,0.00002932047,0.0000015627971,0.000062550476,0.00013173444,0.000007700345],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023584049,0.000010421053,0.00026635555,0.0000340026,0.000110079476,0.000013935164,0.00004357524,0.00027076338,0.008135018,0.0000017612562,0.9901651,0.0009253728],"study_design_scores_gemma":[0.00076885393,0.000091549206,0.0003336247,0.00010509333,0.00003719937,0.0000032405048,0.00015354059,0.0004286891,0.0035936462,0.000021371696,0.99401647,0.000446721],"about_ca_topic_score_codex":0.6216728,"about_ca_topic_score_gemma":0.9601276,"teacher_disagreement_score":0.33845475,"about_ca_system_score_codex":0.00012350404,"about_ca_system_score_gemma":0.0013033464,"threshold_uncertainty_score":0.9999612},"labels":[],"label_agreement":null},{"id":"W6930244462","doi":"10.5281/zenodo.10657445","title":"Assessment 1","year":2024,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Seedling; Context (archaeology); Latitude; Altitude (triangle); Maximum temperature; Pinus <genus>; Picea abies","score_opus":0.015585840029282531,"score_gpt":0.3060674450988687,"score_spread":0.29048160506958615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930244462","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011065457,0.00057338236,0.0016594315,0.000119579934,0.00034517358,0.0002511005,0.9847142,0.00015998901,0.012066484],"genre_scores_gemma":[0.0015469637,0.0006219478,0.00012047706,0.000076188844,0.00051437283,5.209346e-8,0.9955718,0.0009186776,0.0006295498],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987952,0.000083081184,0.00017527016,0.00046846026,0.00021864673,0.00025932773],"domain_scores_gemma":[0.99907583,0.000003272904,0.000043264776,0.0006076965,0.00015700546,0.000112951384],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002819382,0.0001804843,0.00012471591,0.00012996192,0.00046492947,0.00044747442,0.0007570165,0.00016719021,0.0043995087],"category_scores_gemma":[0.00012114322,0.00019230114,0.00007678435,0.00015742934,0.00005791944,0.0000029173916,0.0013959007,0.00031927598,0.010911893],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000064792107,0.00003477446,4.9328666e-8,0.0001473619,0.000066797445,0.000011151208,0.000009500146,0.000051971256,0.0070272842,0.000026591712,0.98744166,0.005176406],"study_design_scores_gemma":[0.00012801209,0.00019671807,0.000022390514,0.000035091798,0.00003484869,0.000082624145,0.000024617417,0.000026767257,0.0007053693,0.000013742963,0.99852026,0.00020954644],"about_ca_topic_score_codex":0.000005843871,"about_ca_topic_score_gemma":5.284259e-7,"teacher_disagreement_score":0.011436935,"about_ca_system_score_codex":0.000047312955,"about_ca_system_score_gemma":0.0000062600852,"threshold_uncertainty_score":0.9965106},"labels":[],"label_agreement":null},{"id":"W6930347949","doi":"10.5281/zenodo.12153334","title":"How to Watch inside Out 2 Online Website","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Casual; Wonder; Studio; Musical; Amateur; Adventure; Fell; Power (physics)","score_opus":0.020236898047048188,"score_gpt":0.28338433785053013,"score_spread":0.26314743980348193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930347949","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010434166,0.0028431187,0.021105228,0.0030047141,0.0007635901,0.00086686044,0.001868877,0.0012064828,0.96729773],"genre_scores_gemma":[0.01589053,0.00044581608,0.00085377065,0.00024131456,0.0014085534,7.562591e-8,0.0059188195,0.010114225,0.9651269],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988475,0.000054108128,0.00012101513,0.0005108631,0.00018484492,0.00028170395],"domain_scores_gemma":[0.9991642,0.0000015578806,0.00003807878,0.0005176811,0.00011186596,0.00016658212],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00012302547,0.00020198603,0.00014530803,0.0001594696,0.00015107493,0.00042511107,0.0005589961,0.00016944675,0.0030159603],"category_scores_gemma":[0.00017839333,0.00021110612,0.000066880944,0.00016405371,0.000041095824,0.0000026195057,0.0010870956,0.00019696914,0.007344057],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009803385,0.000027067306,2.2189305e-7,0.000105141815,0.00006930818,0.000009925578,0.00009566866,0.000017619708,0.04984828,0.000048176582,0.93660074,0.013168031],"study_design_scores_gemma":[0.00013809369,0.00016047145,0.000008525253,0.00007628852,0.000019971289,0.000032861764,0.00006809821,0.000015551866,0.0030446746,0.000012462383,0.9961831,0.00023992939],"about_ca_topic_score_codex":0.000006975999,"about_ca_topic_score_gemma":0.0000054761917,"teacher_disagreement_score":0.05958232,"about_ca_system_score_codex":0.000028637818,"about_ca_system_score_gemma":0.0000026486377,"threshold_uncertainty_score":0.9978954},"labels":[],"label_agreement":null},{"id":"W6930414128","doi":"10.5281/zenodo.12348340","title":"Ieee 323 pdf","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Service (business); Nuclear power; Technical standard; Class (philosophy); Download","score_opus":0.01443384549456368,"score_gpt":0.27142800888902374,"score_spread":0.2569941633944601,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930414128","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000097131866,0.0016628181,0.005550295,0.000083137,0.00036219053,0.00022235294,0.0002009666,0.00038370516,0.9914374],"genre_scores_gemma":[0.0065314206,0.0006662091,0.00021017504,0.000079206606,0.0011599412,5.084078e-8,0.0025490914,0.0091553945,0.97964853],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99900943,0.00005218269,0.00012216091,0.00042219204,0.00015412565,0.00023988131],"domain_scores_gemma":[0.99935037,0.0000013078252,0.000039398044,0.00043545227,0.00007182405,0.000101660735],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00014447719,0.00016800604,0.00011396096,0.0001542977,0.00017745415,0.00022909555,0.0005038021,0.00017601457,0.028951094],"category_scores_gemma":[0.00007224512,0.00018164651,0.00006761631,0.00014265481,0.00006221497,0.0000016326402,0.00049628166,0.00017875578,0.050138637],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000064846067,0.00001744365,6.7369506e-8,0.00011824655,0.00006902999,0.000007497842,0.000033560777,0.000016311453,0.027050052,0.00007275182,0.9640431,0.008565471],"study_design_scores_gemma":[0.00013446847,0.000105957806,0.0000030828057,0.000059563157,0.000019971834,0.000053503296,0.000025047757,0.000022976787,0.0045298194,0.000018735664,0.99482715,0.00019974647],"about_ca_topic_score_codex":0.0000071849463,"about_ca_topic_score_gemma":6.996585e-7,"teacher_disagreement_score":0.030784043,"about_ca_system_score_codex":0.000020605856,"about_ca_system_score_gemma":0.0000025096156,"threshold_uncertainty_score":0.9719366},"labels":[],"label_agreement":null},{"id":"W6930463236","doi":"10.5281/zenodo.11388829","title":"Oxyrrhexis carbonator subsp. texana","year":2024,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Basal (medicine); White (mutation); Taxonomy (biology); Tarsus (eyelids)","score_opus":0.01457225795386055,"score_gpt":0.27265939321226457,"score_spread":0.25808713525840404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930463236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5362644,0.0146407345,0.0996895,0.002297136,0.0015570628,0.0012515759,0.0011520669,0.0028358526,0.34031168],"genre_scores_gemma":[0.99582225,0.0002161766,0.00017324075,0.000060615046,0.00029576727,3.3109963e-8,0.000866838,0.000766911,0.0017981874],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991538,0.000051176496,0.00011607813,0.0003177597,0.00013832255,0.00022285969],"domain_scores_gemma":[0.99948657,0.0000041741127,0.000013127729,0.00028396436,0.00010974494,0.00010244144],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00021500853,0.00009936623,0.0000651721,0.00008768511,0.00035695834,0.00023924756,0.00035654218,0.00006165488,0.0016984795],"category_scores_gemma":[0.000121607256,0.00010440951,0.00005085366,0.00020562198,0.000051683757,0.000006148497,0.00040477456,0.000115945135,0.0013911022],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033536944,0.000049063736,0.000005276816,0.00014191153,0.000112425776,0.000028318324,0.0003594067,0.00028383656,0.5477388,0.0020949058,0.3285318,0.12062071],"study_design_scores_gemma":[0.000115621275,0.00011645997,0.00017971164,0.000015856554,0.000008906028,0.00007972286,0.000055464923,0.00052657665,0.025845764,0.00003933037,0.9728887,0.00012787452],"about_ca_topic_score_codex":0.0000051245042,"about_ca_topic_score_gemma":2.7995102e-7,"teacher_disagreement_score":0.6443569,"about_ca_system_score_codex":0.000026915935,"about_ca_system_score_gemma":0.0000034189989,"threshold_uncertainty_score":0.9993864},"labels":[],"label_agreement":null},{"id":"W6930703452","doi":"10.5281/zenodo.15753264","title":"Fig. 12 in A revision of Parapterogramma Papp and Pseudopterogramma Papp, with a review of the Parapterogramma genus group of the Pacific and Indomalayan regions (Diptera, Sphaeroceridae, Limosininae)","year":2025,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Paratype; Holotype; Aedeagus; Genus; Group (periodic table); Scale (ratio)","score_opus":0.010147451531139173,"score_gpt":0.24090492674605662,"score_spread":0.23075747521491746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930703452","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24926063,0.39117423,0.017453467,0.003049811,0.00075715926,0.018524222,0.0023785501,0.00056854496,0.31683338],"genre_scores_gemma":[0.9491675,0.04402532,0.00067697983,0.00008614835,0.000064770386,7.1412774e-7,0.00037950487,0.0011453026,0.0044537643],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998665,0.00023166326,0.00034464456,0.00035429263,0.00020631327,0.00019809495],"domain_scores_gemma":[0.99885774,0.00001039561,0.00028498282,0.0006602236,0.00012871381,0.000057962614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033327192,0.00020271046,0.00031353487,0.00010484327,0.0001332803,0.00004395361,0.00051598594,0.00013079506,0.00016541773],"category_scores_gemma":[0.00014177033,0.000141899,0.00008687472,0.00033681738,0.0003432094,0.000004599307,0.00069885,0.00017606157,0.00000230036],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049974734,0.00053987844,0.0029694291,0.021792047,0.00066470995,0.000012849436,0.0010070514,0.000024605853,0.013520796,0.0012288358,0.145006,0.81273407],"study_design_scores_gemma":[0.0006140728,0.00037091487,0.0024736233,0.005248616,0.00007043935,0.000048374943,0.00009294843,0.000010103487,0.0010248685,0.0000064343003,0.9898788,0.00016084625],"about_ca_topic_score_codex":0.00004939816,"about_ca_topic_score_gemma":0.000013333287,"teacher_disagreement_score":0.8448728,"about_ca_system_score_codex":0.000009077146,"about_ca_system_score_gemma":0.000007492561,"threshold_uncertainty_score":0.5786473},"labels":[],"label_agreement":null},{"id":"W6930866608","doi":"10.5281/zenodo.15457278","title":"DEVELOPMENT OF CLAY-POLYMER NANOCOMPOSITES (PNC) FOR INDUSTRIAL APPLICATION","year":2009,"lang":"en","type":"article","venue":"NPARC","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nanocomposite; Process (computing); Nanoparticle; Carbon nanotube; Manufacturing process","score_opus":0.013007374553525177,"score_gpt":0.2864236908799071,"score_spread":0.2734163163263819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930866608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86695105,0.00020673746,0.1304267,0.00009843462,0.000061264174,0.0002653673,0.0000060905727,0.000009290451,0.0019750423],"genre_scores_gemma":[0.9771393,0.000004991618,0.022446657,0.000049576985,0.00013720675,0.000025928979,0.00006213837,0.0000054641123,0.00012877164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99962044,0.0000030684316,0.00012574556,0.00011476484,0.000044557255,0.00009144497],"domain_scores_gemma":[0.99980116,0.0000034241434,0.000029193076,0.00010950326,0.000024216564,0.000032499458],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005124605,0.00005765301,0.00006286197,0.000016693673,0.00002489658,0.0000033772099,0.000069209316,0.00007363633,0.0000069905177],"category_scores_gemma":[0.000009920837,0.000057765796,0.000031438696,0.000029513341,0.000008182903,6.745429e-7,0.000012840588,0.000020569478,0.0000010120283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027873568,0.000021383516,0.000057393834,0.0000042449565,0.000009221595,2.083308e-8,0.00002970875,0.000019560495,0.921393,0.00012975137,0.0004372735,0.077870615],"study_design_scores_gemma":[0.00032635964,0.000073870244,0.000294146,0.0000039389406,0.0000053966005,7.3307365e-7,0.000007881744,0.000081003636,0.9619816,0.00006457875,0.037092727,0.000067769586],"about_ca_topic_score_codex":2.590971e-7,"about_ca_topic_score_gemma":7.3587285e-7,"teacher_disagreement_score":0.11018819,"about_ca_system_score_codex":0.0000040365826,"about_ca_system_score_gemma":0.000035748482,"threshold_uncertainty_score":0.23556207},"labels":[],"label_agreement":null},{"id":"W6930919915","doi":"10.5281/zenodo.154449","title":"JuliaLang/julia: 0.4.7 bugfix release","year":2016,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Perimeter Institute","funders":"","keywords":"Simple (philosophy); Process (computing); Production (economics); Work (physics); Component (thermodynamics); Set (abstract data type)","score_opus":0.01144114428952577,"score_gpt":0.26833383849009074,"score_spread":0.256892694200565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930919915","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019939063,0.0009792387,0.0126850195,0.00018033505,0.0002494544,0.00034083927,0.0005460479,0.0005160392,0.98430365],"genre_scores_gemma":[0.029326536,0.0018571198,0.00046276144,0.00016669022,0.0022410438,1.3041122e-7,0.005821219,0.013585907,0.94653857],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988456,0.00008484963,0.00014614145,0.0004408599,0.00018047041,0.00030211214],"domain_scores_gemma":[0.99909604,0.0000029323267,0.000076981676,0.0005600656,0.00011135281,0.00015261791],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000148841,0.00019623805,0.00014864892,0.00014146412,0.00029836808,0.00013441144,0.0006239401,0.00020537237,0.022290496],"category_scores_gemma":[0.00017064608,0.00018689234,0.00007208633,0.000094696916,0.0000852066,0.000002699415,0.00065681397,0.00013651085,0.008602736],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019452717,0.0000264878,6.294853e-7,0.00005538033,0.000056660378,0.000007009014,0.000024138897,0.0000050966432,0.030110156,0.00009970263,0.9402994,0.029295905],"study_design_scores_gemma":[0.00035079004,0.00010352872,0.000017033044,0.00005458246,0.00001537958,0.00003363727,0.000020075975,0.000005749237,0.0034972182,0.00001074362,0.995652,0.00023924214],"about_ca_topic_score_codex":0.000010691597,"about_ca_topic_score_gemma":0.0000010012405,"teacher_disagreement_score":0.055352636,"about_ca_system_score_codex":0.00002833395,"about_ca_system_score_gemma":0.000003913803,"threshold_uncertainty_score":0.9921692},"labels":[],"label_agreement":null},{"id":"W6931108450","doi":"10.5281/zenodo.4754353","title":"Data from: Reversal of the adipostat control of torpor during migration in hummingbirds","year":2021,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Toronto","funders":"","keywords":"Torpor; Evening; Energy expenditure; Hibernation (computing); Homeothermy; Metabolic rate; Facultative; Respirometry","score_opus":0.021147123141293394,"score_gpt":0.269517741141081,"score_spread":0.24837061799978763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931108450","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36424395,0.032384366,0.04238556,0.0011637858,0.0018609145,0.0046558506,0.037673015,0.00051686383,0.5151157],"genre_scores_gemma":[0.9639469,0.00075362634,0.00035709052,0.000027387387,0.0003232715,4.948006e-8,0.009383281,0.0024082072,0.022800205],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991773,0.000110344,0.00018248806,0.0002720006,0.00014475363,0.00011311361],"domain_scores_gemma":[0.9990379,0.0000043736695,0.00012402263,0.0007158385,0.00008851467,0.000029301564],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014830628,0.0000931486,0.00013521893,0.00006903298,0.00008250138,0.000027819942,0.0007104005,0.00010007914,0.0032918593],"category_scores_gemma":[0.00025237942,0.00008907385,0.000036295965,0.00013235195,0.000058192087,0.0000027749606,0.0007960151,0.0001005538,0.00002283083],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005693903,0.00006760689,0.00007307319,0.00023008011,0.00013404172,0.0000034656057,0.00015170517,0.0001358369,0.795111,0.000022153017,0.20110612,0.0029079863],"study_design_scores_gemma":[0.0005635868,0.000048345297,0.0017674366,0.00016606906,0.000025120866,0.0000064773567,0.00007456646,0.00012716555,0.041051637,0.0000022001059,0.9560564,0.0001109517],"about_ca_topic_score_codex":0.00010413848,"about_ca_topic_score_gemma":0.000042717566,"teacher_disagreement_score":0.75495034,"about_ca_system_score_codex":0.000014326016,"about_ca_system_score_gemma":0.0000060323496,"threshold_uncertainty_score":0.9976193},"labels":[],"label_agreement":null},{"id":"W6931700575","doi":"10.5281/zenodo.7893848","title":"OSeMOSYS/otoole: otoole v1.0.3","year":2023,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Documentation; Field (mathematics); Lock (firearm); Data file; Software","score_opus":0.016359004163771187,"score_gpt":0.272715518440275,"score_spread":0.2563565142765038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931700575","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00039668122,0.0011015744,0.008557312,0.00017276194,0.00046862345,0.00066580734,0.00078445004,0.0020588853,0.9857939],"genre_scores_gemma":[0.019397812,0.0024869146,0.000616004,0.00019855496,0.0022363965,3.3228395e-7,0.009575474,0.04215611,0.9233324],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99870133,0.00008199788,0.00016768287,0.00049121794,0.00021692783,0.00034085632],"domain_scores_gemma":[0.9990712,0.0000041541093,0.00007430763,0.0006036368,0.00011342947,0.00013329978],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00020994342,0.00021023197,0.00015761482,0.00018000863,0.00036868025,0.00020990372,0.00069533713,0.00022401976,0.008259747],"category_scores_gemma":[0.00024688718,0.00023566667,0.0000776393,0.00023496502,0.00007306393,0.000003162455,0.0008938321,0.00018836242,0.009421881],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011428688,0.000027047887,8.815142e-7,0.000066856344,0.00007353633,0.000008172388,0.000035914138,0.00004171016,0.013487109,0.00009349598,0.9610438,0.025110072],"study_design_scores_gemma":[0.0002651336,0.00012465744,0.000050903713,0.000054422795,0.000016136393,0.000035094396,0.000039406164,0.00003806204,0.003043838,0.000008010222,0.99606365,0.0002606856],"about_ca_topic_score_codex":0.00002229677,"about_ca_topic_score_gemma":0.0000042901897,"teacher_disagreement_score":0.062461507,"about_ca_system_score_codex":0.000031158714,"about_ca_system_score_gemma":0.00000397895,"threshold_uncertainty_score":0.9926468},"labels":[],"label_agreement":null},{"id":"W6931707147","doi":"10.5281/zenodo.5556811","title":"Pandarus libanicus Desbrochers des Loges 1881","year":2021,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Synonym (taxonomy); Taxonomy (biology); Ridiculous; Locus (genetics)","score_opus":0.021077832258688787,"score_gpt":0.2745194053167347,"score_spread":0.2534415730580459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931707147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8067308,0.004947524,0.092069924,0.00048947666,0.0002714682,0.00034158138,0.0001979619,0.0005374739,0.09441381],"genre_scores_gemma":[0.9949962,0.0005662263,0.0009438404,0.00009853007,0.00017086016,2.9570977e-8,0.0012133969,0.0005794823,0.0014314171],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991327,0.000088847446,0.00012044447,0.00029108181,0.00012216148,0.00024474668],"domain_scores_gemma":[0.9992688,0.0000041561448,0.000024587263,0.00028795318,0.00030250725,0.000112002665],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016827797,0.00009655988,0.0000759351,0.00003785427,0.0006334919,0.00021829033,0.00030428352,0.00006442887,0.0018960623],"category_scores_gemma":[0.00036991888,0.00010693443,0.0000485121,0.00017633256,0.000091961774,0.0000065474223,0.0005273612,0.000094363066,0.0005126379],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030290134,0.00006137587,0.00001238775,0.000044131884,0.000056308094,0.000023367762,0.0002606441,0.00027817857,0.86071116,0.0002072028,0.056336798,0.08197819],"study_design_scores_gemma":[0.00025513434,0.00011446513,0.0004795405,0.000009738575,0.000008761847,0.00013946294,0.00023885746,0.000040945062,0.1907411,0.00005460582,0.80779266,0.00012469906],"about_ca_topic_score_codex":0.0000030097397,"about_ca_topic_score_gemma":6.2651935e-7,"teacher_disagreement_score":0.7514559,"about_ca_system_score_codex":0.000026136158,"about_ca_system_score_gemma":0.0000054165534,"threshold_uncertainty_score":0.99901634},"labels":[],"label_agreement":null},{"id":"W6939120177","doi":"10.60692/amk7k-wpk32","title":"Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria","year":2021,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Malaria; Gene drive; Medical research; Anopheles; Control (management); Informed consent","score_opus":0.047755883972011415,"score_gpt":0.30820143674726075,"score_spread":0.26044555277524933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939120177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99470556,0.000034369034,0.0037876053,0.000036253958,0.000037968104,0.00034352043,0.000108219916,0.000008843828,0.0009376863],"genre_scores_gemma":[0.99846804,0.000002929444,0.0011391719,0.000029972518,0.000031685784,0.00007938538,0.00017356871,0.000008353812,0.00006689498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922085,0.000041878222,0.00028598524,0.000115079216,0.00015016609,0.00018604154],"domain_scores_gemma":[0.99946666,0.000007593618,0.00006268096,0.00017920433,0.0002228755,0.0000609893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005600871,0.00009730552,0.00013131251,0.00008396713,0.00008829145,0.000052664047,0.00010375102,0.00011164362,0.0000036252343],"category_scores_gemma":[0.000029375657,0.000092765265,0.000024331724,0.000104732215,0.000024045567,0.000014930231,0.00006733932,0.00009726775,0.0000023386908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010454998,0.00013212416,0.02511852,0.0026048701,0.0002438229,0.0000037947786,0.3163963,0.0007105993,0.6459539,0.00027357048,0.005724311,0.001792711],"study_design_scores_gemma":[0.0011950496,0.00025335222,0.004090199,0.00011079867,0.0000043815257,0.0000082205825,0.05301573,0.000942969,0.9386774,0.0000019821523,0.0015535493,0.00014639196],"about_ca_topic_score_codex":0.000004613541,"about_ca_topic_score_gemma":4.667135e-7,"teacher_disagreement_score":0.2927235,"about_ca_system_score_codex":0.00002848879,"about_ca_system_score_gemma":0.000024216466,"threshold_uncertainty_score":0.37828577},"labels":[],"label_agreement":null},{"id":"W6939208752","doi":"10.60692/y0vcn-etw36","title":"Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria","year":2021,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Malaria; Gene drive; Medical research; Anopheles; Control (management); Informed consent","score_opus":0.047755883972011415,"score_gpt":0.30820143674726075,"score_spread":0.26044555277524933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939208752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99470556,0.000034369034,0.0037876053,0.000036253958,0.000037968104,0.00034352043,0.000108219916,0.000008843828,0.0009376863],"genre_scores_gemma":[0.99846804,0.000002929444,0.0011391719,0.000029972518,0.000031685784,0.00007938538,0.00017356871,0.000008353812,0.00006689498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922085,0.000041878222,0.00028598524,0.000115079216,0.00015016609,0.00018604154],"domain_scores_gemma":[0.99946666,0.000007593618,0.00006268096,0.00017920433,0.0002228755,0.0000609893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005600871,0.00009730552,0.00013131251,0.00008396713,0.00008829145,0.000052664047,0.00010375102,0.00011164362,0.0000036252343],"category_scores_gemma":[0.000029375657,0.000092765265,0.000024331724,0.000104732215,0.000024045567,0.000014930231,0.00006733932,0.00009726775,0.0000023386908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010454998,0.00013212416,0.02511852,0.0026048701,0.0002438229,0.0000037947786,0.3163963,0.0007105993,0.6459539,0.00027357048,0.005724311,0.001792711],"study_design_scores_gemma":[0.0011950496,0.00025335222,0.004090199,0.00011079867,0.0000043815257,0.0000082205825,0.05301573,0.000942969,0.9386774,0.0000019821523,0.0015535493,0.00014639196],"about_ca_topic_score_codex":0.000004613541,"about_ca_topic_score_gemma":4.667135e-7,"teacher_disagreement_score":0.2927235,"about_ca_system_score_codex":0.00002848879,"about_ca_system_score_gemma":0.000024216466,"threshold_uncertainty_score":0.37828577},"labels":[],"label_agreement":null},{"id":"W6939275266","doi":"10.6084/m9.figshare.16614647.v1","title":"Additional file 3 of Development of a Csy4-processed guide RNA delivery system with soybean-infecting virus ALSV for genome editing","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Sanger sequencing; Genome; Genome editing; RNA; Gene; DNA sequencing; Raw data; Genomics","score_opus":0.011987280997346453,"score_gpt":0.248599405021447,"score_spread":0.23661212402410056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939275266","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028309342,0.00027393072,0.00091648404,0.0000015304579,0.000016157772,0.000121373756,0.9948919,0.0000120434015,0.0009356661],"genre_scores_gemma":[0.121324524,7.1323893e-7,0.016050654,0.000015067163,0.0002362303,0.00045246317,0.8617104,0.000023613098,0.00018628512],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993386,0.00000665207,0.00022548951,0.00018785038,0.000099145494,0.00014220791],"domain_scores_gemma":[0.99922615,0.00010702327,0.00012968344,0.00011931886,0.000381254,0.000036566056],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000025006448,0.00009964512,0.00013108902,0.000022990807,0.00004988135,0.000008973236,0.000078013465,0.00006365521,0.19548455],"category_scores_gemma":[0.0006612927,0.00010079422,0.000055828255,0.00006863193,0.00000403084,0.0000031938303,0.00006732953,0.00003269801,0.000010570932],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000114258155,0.000024612122,0.0000019032356,0.0013802525,0.00010208015,0.0000045293023,0.00006789041,0.00068703055,0.32803044,5.235461e-7,0.66821027,0.0014790755],"study_design_scores_gemma":[0.0001707729,0.00004389344,0.0002210444,0.0014431457,0.0000063005086,0.000012324161,0.00021682677,0.00021190931,0.6393731,1.817364e-7,0.35818604,0.00011442159],"about_ca_topic_score_codex":0.0000010450045,"about_ca_topic_score_gemma":0.00002160326,"teacher_disagreement_score":0.31134272,"about_ca_system_score_codex":0.000015153757,"about_ca_system_score_gemma":0.0003131972,"threshold_uncertainty_score":0.8052509},"labels":[],"label_agreement":null},{"id":"W6939449318","doi":"10.6084/m9.figshare.13250775.v1","title":"Additional file 1 of A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Drosophila (subgenus); RNA; Drosophila melanogaster; Key (lock); Base sequence","score_opus":0.02921508852160704,"score_gpt":0.27915616420304196,"score_spread":0.24994107568143492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939449318","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027813148,0.00003588988,0.000110527224,0.00005943873,0.000008138476,0.00014487913,0.99889207,0.000007013336,0.0004639316],"genre_scores_gemma":[0.16882263,2.064066e-7,0.0009773225,0.00014817207,0.00013008143,0.00035687574,0.8295034,0.000011257937,0.00005004283],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995942,0.0000051967004,0.000109186934,0.00014392831,0.000057029672,0.000090467045],"domain_scores_gemma":[0.99972326,0.00007734497,0.000036598132,0.000081068516,0.000045729048,0.000035997145],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000068013815,0.00006690015,0.00006955377,0.000018359198,0.000012623625,0.000004928971,0.00006921482,0.00006538894,0.73427665],"category_scores_gemma":[0.00094802625,0.00007715178,0.000058250305,0.000055599998,0.0000026210753,0.0000019903573,0.000024358347,0.00003123704,0.000054915297],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002326246,0.000009844029,0.0000026013197,0.000086187116,0.000004599678,7.186748e-7,0.00000984555,0.0022425407,0.008368872,7.5247783e-7,0.98894906,0.00030173088],"study_design_scores_gemma":[0.000363619,0.00013837742,0.001794444,0.00022352216,0.0000026708506,5.5013146e-7,0.00001173641,0.011623543,0.056782804,0.0000070273,0.9289331,0.0001185986],"about_ca_topic_score_codex":6.489753e-7,"about_ca_topic_score_gemma":0.0000037907948,"teacher_disagreement_score":0.7342217,"about_ca_system_score_codex":0.0000053651365,"about_ca_system_score_gemma":0.00004456664,"threshold_uncertainty_score":0.31461585},"labels":[],"label_agreement":null},{"id":"W6939630380","doi":"10.6084/m9.figshare.28106316.v1","title":"Additional file 1 of A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Pseudomonas putida; Genome editing; Genome; CRISPR; DNA","score_opus":0.016283185129113274,"score_gpt":0.26404371154053274,"score_spread":0.24776052641141946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939630380","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019995155,0.0011713174,0.00032356675,0.000020227468,0.00008290961,0.000280263,0.9967454,0.000032070257,0.0011442726],"genre_scores_gemma":[0.15149929,0.0000010061037,0.0016684085,0.000040481456,0.00051895337,0.0013325125,0.84460133,0.00003747281,0.00030053873],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99904567,0.000020066665,0.00024253035,0.0003336259,0.00011422698,0.00024389317],"domain_scores_gemma":[0.9993048,0.00030210693,0.000057052504,0.00016143669,0.000117718715,0.000056929723],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000038003975,0.00016496176,0.0001608756,0.000089625086,0.000040642302,0.00004412051,0.00012557092,0.00012780009,0.3781981],"category_scores_gemma":[0.0005919966,0.00017259762,0.00013492517,0.0001383289,0.000008774627,0.0000073778365,0.00004795018,0.00008521284,0.000102487196],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016943237,0.000024056812,7.319008e-7,0.0009708223,0.000029681787,0.000013024224,0.000028910046,0.0016662985,0.03229841,0.0000036216284,0.9643573,0.0005902098],"study_design_scores_gemma":[0.00024434368,0.00017674871,0.000045096007,0.0031925049,0.000007678102,0.000021274505,0.00009207951,0.0072503644,0.10510797,0.0000036735075,0.88365424,0.00020402698],"about_ca_topic_score_codex":0.000001729075,"about_ca_topic_score_gemma":0.000008957273,"teacher_disagreement_score":0.3780956,"about_ca_system_score_codex":0.000038916536,"about_ca_system_score_gemma":0.00012462193,"threshold_uncertainty_score":0.7038326},"labels":[],"label_agreement":null},{"id":"W6939671814","doi":"10.6084/m9.figshare.17084288","title":"Additional file 2 of Revealing the composition of the eukaryotic microbiome of oyster spat by CRISPR-Cas Selective Amplicon Sequencing (CCSAS)","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Amplicon; Oyster; Gene; Composition (language); Ribosomal RNA; Table (database); DNA sequencing; Microbiome","score_opus":0.010418414458077011,"score_gpt":0.24779926598072055,"score_spread":0.23738085152264354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939671814","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009879558,0.00036009427,0.000055189477,0.000022969505,0.000019842882,0.00010255231,0.9892913,0.0000026252642,0.00026585278],"genre_scores_gemma":[0.5592023,0.000002253829,0.00020778952,0.000060961767,0.00004633028,0.000045259298,0.44026265,0.000010418716,0.00016199212],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994775,0.000037293034,0.00017204124,0.0001356271,0.000082509025,0.00009501975],"domain_scores_gemma":[0.9993404,0.000111810434,0.000121339406,0.00020939534,0.00020122803,0.000015803165],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019181518,0.00007918111,0.000104797364,0.000012462324,0.00003630678,0.0000048906354,0.00012481472,0.00006592788,0.18516824],"category_scores_gemma":[0.00025945905,0.000059924514,0.00009607523,0.00010989072,0.000016794442,0.0000022624822,0.00009572214,0.00006344071,0.000007338536],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002668509,0.00000772049,0.0000044659696,0.00007735324,0.000020055535,2.4496867e-7,0.000027589133,0.00015825225,0.48126268,3.141122e-7,0.5184052,0.00003345052],"study_design_scores_gemma":[0.00008198191,0.00003095671,0.0015927674,0.00082417816,0.000010681064,0.000022156572,0.000057345427,0.000092560345,0.96930736,0.0000038872577,0.027909053,0.0000670541],"about_ca_topic_score_codex":0.000005680538,"about_ca_topic_score_gemma":0.000008426316,"teacher_disagreement_score":0.5493228,"about_ca_system_score_codex":0.000014684115,"about_ca_system_score_gemma":0.00008000859,"threshold_uncertainty_score":0.8155766},"labels":[],"label_agreement":null},{"id":"W6949683934","doi":"10.5281/zenodo.3686300","title":"Generation of Knockout Cell Lines Using CRISPR-Cas9 Technology","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cell culture; Cell; Genome; Set (abstract data type); Protocol (science)","score_opus":0.05297389630115775,"score_gpt":0.29405869083927016,"score_spread":0.2410847945381124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6949683934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82246745,0.0007738229,0.16987135,0.0006374105,0.00008910191,0.00026930196,0.000083236744,0.0001841531,0.0056241876],"genre_scores_gemma":[0.99712116,0.00008850007,0.0016414698,0.00007335333,0.00024471222,1.6291557e-8,0.00040701593,0.0003471088,0.00007665236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993045,0.000044206787,0.0001605005,0.00023983451,0.00009918629,0.00015179759],"domain_scores_gemma":[0.99942154,0.0000016233612,0.000053316213,0.00020737667,0.00024435393,0.00007176861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819455,0.00008444282,0.000087083026,0.0000752522,0.0002749443,0.000055167635,0.00031169588,0.00007900711,0.00042314833],"category_scores_gemma":[0.00018868063,0.00009438125,0.00003397552,0.00024228418,0.000056647612,0.000005361691,0.00042991142,0.00008336587,0.00012953125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000151489,0.000023993405,0.000005573675,0.00003917681,0.0000128383435,0.0000012939075,0.00012464478,0.0019370975,0.98059475,0.00007077826,0.00918454,0.007990177],"study_design_scores_gemma":[0.00021691405,0.00020426877,0.000024740872,0.000004610468,0.0000093064955,0.000017594351,0.000106538035,0.0043285177,0.6581186,0.000005430536,0.3368736,0.00008990676],"about_ca_topic_score_codex":0.0000023435234,"about_ca_topic_score_gemma":1.0154071e-7,"teacher_disagreement_score":0.32768905,"about_ca_system_score_codex":0.00001077068,"about_ca_system_score_gemma":0.0000033342696,"threshold_uncertainty_score":0.46331775},"labels":[],"label_agreement":null},{"id":"W6958132427","doi":"10.60692/hhtk6-1gq63","title":"Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria","year":2021,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Malaria; Gene drive; Medical research; Anopheles; Control (management); Informed consent","score_opus":0.047755883972011415,"score_gpt":0.30820143674726075,"score_spread":0.26044555277524933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958132427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99470556,0.000034369034,0.0037876053,0.000036253958,0.000037968104,0.00034352043,0.000108219916,0.000008843828,0.0009376863],"genre_scores_gemma":[0.99846804,0.000002929444,0.0011391719,0.000029972518,0.000031685784,0.00007938538,0.00017356871,0.000008353812,0.00006689498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922085,0.000041878222,0.00028598524,0.000115079216,0.00015016609,0.00018604154],"domain_scores_gemma":[0.99946666,0.000007593618,0.00006268096,0.00017920433,0.0002228755,0.0000609893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005600871,0.00009730552,0.00013131251,0.00008396713,0.00008829145,0.000052664047,0.00010375102,0.00011164362,0.0000036252343],"category_scores_gemma":[0.000029375657,0.000092765265,0.000024331724,0.000104732215,0.000024045567,0.000014930231,0.00006733932,0.00009726775,0.0000023386908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010454998,0.00013212416,0.02511852,0.0026048701,0.0002438229,0.0000037947786,0.3163963,0.0007105993,0.6459539,0.00027357048,0.005724311,0.001792711],"study_design_scores_gemma":[0.0011950496,0.00025335222,0.004090199,0.00011079867,0.0000043815257,0.0000082205825,0.05301573,0.000942969,0.9386774,0.0000019821523,0.0015535493,0.00014639196],"about_ca_topic_score_codex":0.000004613541,"about_ca_topic_score_gemma":4.667135e-7,"teacher_disagreement_score":0.2927235,"about_ca_system_score_codex":0.00002848879,"about_ca_system_score_gemma":0.000024216466,"threshold_uncertainty_score":0.37828577},"labels":[],"label_agreement":null},{"id":"W6958253994","doi":"10.6084/m9.figshare.14167687","title":"Additional file 1 of STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Exon; Gene; Transfection; RNA splicing; Stop codon; Cell cycle; Plasmid; Cell culture","score_opus":0.0064956029972011,"score_gpt":0.2337810532830489,"score_spread":0.22728545028584782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958253994","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020093461,0.00166087,0.000004005351,0.000110062414,0.0000049255787,0.0004905209,0.9772382,0.0000025213178,0.00039544798],"genre_scores_gemma":[0.62442523,0.00003482799,0.00022483579,0.000151364,0.00004964726,0.0012376743,0.37297657,0.000014063871,0.0008857937],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948066,0.000036423404,0.00012570861,0.00015714591,0.00008868323,0.00011137077],"domain_scores_gemma":[0.99959457,0.00016267462,0.000043927037,0.00012953537,0.000045143144,0.000024137367],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000036184145,0.00009451671,0.00012441441,0.000009834836,0.00004336948,0.000022467317,0.00007120559,0.000068991554,0.1235897],"category_scores_gemma":[0.00016714154,0.000057180623,0.000044710774,0.00004206671,0.000022797061,0.0000027295866,0.000043481792,0.00005918604,0.0000035761475],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007630131,0.000034755703,8.120107e-7,0.0001137055,0.000012668541,0.0000037224252,0.00015458731,0.0000073051633,0.1604262,3.0797838e-7,0.8380136,0.001156075],"study_design_scores_gemma":[0.0020301256,0.00006637144,0.0002679121,0.00048490602,0.0000051347206,0.00000801743,0.0001578884,0.00035458987,0.8339366,0.00001018756,0.16257997,0.00009830463],"about_ca_topic_score_codex":0.0000031777897,"about_ca_topic_score_gemma":0.0000155412,"teacher_disagreement_score":0.6754336,"about_ca_system_score_codex":0.0000019547128,"about_ca_system_score_gemma":0.000044420583,"threshold_uncertainty_score":0.87721145},"labels":[],"label_agreement":null},{"id":"W6958463450","doi":"10.6084/m9.figshare.28975055.v1","title":"Additional file 1 of Predicting adenine base editing efficiencies in different cellular contexts by deep learning","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"","keywords":"Deep learning; Base (topology); File format; Focus (optics); Key (lock)","score_opus":0.004653377892996529,"score_gpt":0.23025878211324435,"score_spread":0.22560540422024783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958463450","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009310883,0.00077456445,0.000120162775,0.000007914387,0.00003279143,0.000087374356,0.9886599,0.000014135155,0.0009922661],"genre_scores_gemma":[0.3748938,0.0000010301843,0.000075174816,0.000022564922,0.00012354628,0.00015162122,0.62418276,0.000007389347,0.0005421002],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994192,0.000018135732,0.00015671899,0.0001748006,0.000080406695,0.00015072475],"domain_scores_gemma":[0.9995911,0.00018556797,0.00005213661,0.00008916345,0.000054117067,0.00002791131],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000017886168,0.000096691045,0.000101177764,0.000042179698,0.00003776595,0.000009034687,0.00009358884,0.00007454235,0.5125082],"category_scores_gemma":[0.0029526697,0.000097473356,0.00004847254,0.000080378435,0.0000070650713,0.0000018592561,0.0000962374,0.00010542236,0.00001351986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003781521,0.000019856097,0.00009384311,0.00007629112,0.0000088249635,0.0000013980647,0.000019560312,0.0010400881,0.04962533,1.7761424e-7,0.9481953,0.00091556786],"study_design_scores_gemma":[0.00036351645,0.00009654711,0.0041574915,0.002169473,0.000005558838,0.0000017486798,0.00023791983,0.01046491,0.34455898,0.000001676665,0.6377562,0.00018593101],"about_ca_topic_score_codex":0.0000013449885,"about_ca_topic_score_gemma":0.000007666846,"teacher_disagreement_score":0.5124947,"about_ca_system_score_codex":0.000009248453,"about_ca_system_score_gemma":0.000021562584,"threshold_uncertainty_score":0.48793742},"labels":[],"label_agreement":null},{"id":"W6961548729","doi":"10.14288/1.0079601","title":"The Daily Canadian","year":2015,"lang":"en","type":"article","venue":"Open Collections","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Government (linguistics); Work (physics); Perspective (graphical); Variety (cybernetics)","score_opus":0.0143809865319501,"score_gpt":0.29720521072864176,"score_spread":0.2828242241966917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6961548729","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002339799,0.00050500454,0.0020348786,0.0007991373,0.0006144788,0.0002822426,0.000018010815,0.0000075349626,0.9933989],"genre_scores_gemma":[0.35824192,0.000073377196,0.0006273439,0.00023851884,0.00021753383,0.00009117896,0.000024745106,0.000015445461,0.64046997],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.999693,0.000011766696,0.00004909762,0.00008842008,0.000033095734,0.00012463494],"domain_scores_gemma":[0.9996249,0.0000040767113,0.000007066474,0.00017675397,0.000048174858,0.00013901065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010617319,0.00003994103,0.00002867548,0.000009255935,0.0008602019,0.00034373303,0.00019656426,0.00003071302,0.00001947529],"category_scores_gemma":[0.000059021433,0.000032153403,0.00001592952,0.00014400111,0.000016142096,0.0000011866086,0.00006329784,0.00003164548,0.000008714195],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000058719497,0.0000038263274,0.000041565752,2.2214628e-7,0.000013069491,5.1885877e-7,0.000018261459,0.00042405416,0.00088796084,0.000031675547,0.99803364,0.0005393409],"study_design_scores_gemma":[0.00015076618,0.000047116304,0.00009825519,7.621307e-7,0.0000032794985,0.000011391268,0.00017300296,0.00009616972,0.004289734,0.00010453285,0.994972,0.000052998235],"about_ca_topic_score_codex":0.108220994,"about_ca_topic_score_gemma":0.576279,"teacher_disagreement_score":0.46805796,"about_ca_system_score_codex":0.000021906702,"about_ca_system_score_gemma":0.0003370389,"threshold_uncertainty_score":0.8977174},"labels":[],"label_agreement":null},{"id":"W6968561963","doi":"10.5281/zenodo.3669099","title":"Generation of Knockout Cell Lines Using CRISPR-Cas9 Technology","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cell culture; Cell; Genome; Set (abstract data type); Protocol (science)","score_opus":0.05297389630115775,"score_gpt":0.29405869083927016,"score_spread":0.2410847945381124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6968561963","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82246745,0.0007738229,0.16987135,0.0006374105,0.00008910191,0.00026930196,0.000083236744,0.0001841531,0.0056241876],"genre_scores_gemma":[0.99712116,0.00008850007,0.0016414698,0.00007335333,0.00024471222,1.6291557e-8,0.00040701593,0.0003471088,0.00007665236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993045,0.000044206787,0.0001605005,0.00023983451,0.00009918629,0.00015179759],"domain_scores_gemma":[0.99942154,0.0000016233612,0.000053316213,0.00020737667,0.00024435393,0.00007176861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819455,0.00008444282,0.000087083026,0.0000752522,0.0002749443,0.000055167635,0.00031169588,0.00007900711,0.00042314833],"category_scores_gemma":[0.00018868063,0.00009438125,0.00003397552,0.00024228418,0.000056647612,0.000005361691,0.00042991142,0.00008336587,0.00012953125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000151489,0.000023993405,0.000005573675,0.00003917681,0.0000128383435,0.0000012939075,0.00012464478,0.0019370975,0.98059475,0.00007077826,0.00918454,0.007990177],"study_design_scores_gemma":[0.00021691405,0.00020426877,0.000024740872,0.000004610468,0.0000093064955,0.000017594351,0.000106538035,0.0043285177,0.6581186,0.000005430536,0.3368736,0.00008990676],"about_ca_topic_score_codex":0.0000023435234,"about_ca_topic_score_gemma":1.0154071e-7,"teacher_disagreement_score":0.32768905,"about_ca_system_score_codex":0.00001077068,"about_ca_system_score_gemma":0.0000033342696,"threshold_uncertainty_score":0.46331775},"labels":[],"label_agreement":null},{"id":"W6968933257","doi":"10.5281/zenodo.6646715","title":"Competition and coevolution drive the evolution and the diversification of CRISPR immunity","year":2022,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Genome; CRISPR; Bacteriophage; Gene; Locus (genetics); Sanger sequencing; Point mutation; Mutation","score_opus":0.010911360579708589,"score_gpt":0.23649478565163665,"score_spread":0.22558342507192805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6968933257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89179224,0.0019513979,0.09705482,0.0016491705,0.00010669409,0.0007098724,0.00020829876,0.000072503644,0.006455],"genre_scores_gemma":[0.99921614,0.00018462956,0.000036760874,0.000026198928,0.000026887892,1.1452017e-7,0.00037886034,0.000067069646,0.00006336039],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99934983,0.00026178698,0.00008552778,0.000118572025,0.0001084473,0.000075820266],"domain_scores_gemma":[0.99962467,0.0000112984,0.000048324233,0.0001834111,0.000111681096,0.000020591819],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0005058024,0.000044440425,0.0000441596,0.00003165218,0.001520682,0.000045258235,0.00020299753,0.000016763624,0.00015338125],"category_scores_gemma":[0.0001150239,0.000035601082,0.000017445374,0.000106264786,0.0002124989,0.0000050660988,0.00068136916,0.00009428032,0.000007378703],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010224544,0.00021491197,0.0002391071,0.00013730921,0.00019252629,0.0000010860216,0.006686677,0.0045742835,0.8148336,0.0929624,0.031194942,0.047940727],"study_design_scores_gemma":[0.0038481043,0.0010182963,0.06363302,0.00002093302,0.000108764725,0.00028952892,0.015733872,0.009288774,0.01842253,0.0015718532,0.88570184,0.0003625083],"about_ca_topic_score_codex":0.00003919408,"about_ca_topic_score_gemma":5.2577417e-7,"teacher_disagreement_score":0.85450685,"about_ca_system_score_codex":0.000027168358,"about_ca_system_score_gemma":0.0000017756024,"threshold_uncertainty_score":0.9997792},"labels":[],"label_agreement":null},{"id":"W6976573844","doi":"10.6084/m9.figshare.12421364","title":"Additional file 1 of MAUDE: inferring expression changes in sorting-based CRISPR screens","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"CRISPR; Expression (computer science); Gene expression; Key (lock); DNA","score_opus":0.0226341715666069,"score_gpt":0.278889269724807,"score_spread":0.2562550981582001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976573844","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004461535,0.00007759878,0.00005015183,0.000050544,0.000005353833,0.00006984495,0.99879134,0.000011730665,0.0004972898],"genre_scores_gemma":[0.16331144,8.644675e-7,0.00089060847,0.00026421953,0.00013746538,0.00020063466,0.8351398,0.00001449496,0.000040465377],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99952924,0.0000091714,0.00010508418,0.00016043041,0.000077122786,0.00011897768],"domain_scores_gemma":[0.99971026,0.0000537268,0.00004740716,0.00009907101,0.000035806195,0.000053710697],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000007994184,0.00007941917,0.000079494675,0.00002464295,0.000014392724,0.000004966185,0.00009230107,0.00007173648,0.8314873],"category_scores_gemma":[0.0012182037,0.00008456195,0.000038223854,0.00006603156,0.0000035249661,0.000001489803,0.00007707955,0.000058932586,0.000052254778],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008515411,0.000008613295,0.00001769939,0.00007767306,0.0000025023953,0.0000022145696,0.000012843709,0.0014467321,0.04665205,7.046898e-8,0.9514012,0.00036992115],"study_design_scores_gemma":[0.00016359835,0.000079476304,0.0021663045,0.00082298444,0.0000011596971,7.2966253e-7,0.000023269713,0.00223463,0.39977503,7.8539176e-7,0.59461015,0.00012185765],"about_ca_topic_score_codex":0.0000012722762,"about_ca_topic_score_gemma":0.000025649555,"teacher_disagreement_score":0.8314351,"about_ca_system_score_codex":0.0000032302592,"about_ca_system_score_gemma":0.00003471972,"threshold_uncertainty_score":0.34483364},"labels":[],"label_agreement":null},{"id":"W6976680224","doi":"10.60692/nhymh-y7037","title":"Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria","year":2021,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Malaria; Gene drive; Medical research; Anopheles; Control (management); Informed consent","score_opus":0.047755883972011415,"score_gpt":0.30820143674726075,"score_spread":0.26044555277524933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976680224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99470556,0.000034369034,0.0037876053,0.000036253958,0.000037968104,0.00034352043,0.000108219916,0.000008843828,0.0009376863],"genre_scores_gemma":[0.99846804,0.000002929444,0.0011391719,0.000029972518,0.000031685784,0.00007938538,0.00017356871,0.000008353812,0.00006689498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922085,0.000041878222,0.00028598524,0.000115079216,0.00015016609,0.00018604154],"domain_scores_gemma":[0.99946666,0.000007593618,0.00006268096,0.00017920433,0.0002228755,0.0000609893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005600871,0.00009730552,0.00013131251,0.00008396713,0.00008829145,0.000052664047,0.00010375102,0.00011164362,0.0000036252343],"category_scores_gemma":[0.000029375657,0.000092765265,0.000024331724,0.000104732215,0.000024045567,0.000014930231,0.00006733932,0.00009726775,0.0000023386908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010454998,0.00013212416,0.02511852,0.0026048701,0.0002438229,0.0000037947786,0.3163963,0.0007105993,0.6459539,0.00027357048,0.005724311,0.001792711],"study_design_scores_gemma":[0.0011950496,0.00025335222,0.004090199,0.00011079867,0.0000043815257,0.0000082205825,0.05301573,0.000942969,0.9386774,0.0000019821523,0.0015535493,0.00014639196],"about_ca_topic_score_codex":0.000004613541,"about_ca_topic_score_gemma":4.667135e-7,"teacher_disagreement_score":0.2927235,"about_ca_system_score_codex":0.00002848879,"about_ca_system_score_gemma":0.000024216466,"threshold_uncertainty_score":0.37828577},"labels":[],"label_agreement":null},{"id":"W6976724098","doi":"10.6084/m9.figshare.13250793.v1","title":"Additional file 7 of A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Drosophila (subgenus); RNA; Drosophila melanogaster; Key (lock); Base sequence","score_opus":0.02872874232592238,"score_gpt":0.2789533144687695,"score_spread":0.2502245721428471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976724098","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028050315,0.000036241745,0.00011181776,0.000059462505,0.000008154807,0.0001451327,0.9988864,0.0000070232372,0.000465254],"genre_scores_gemma":[0.17164491,2.0933408e-7,0.00096436625,0.00014799046,0.0001300083,0.0003490444,0.8267027,0.00001123286,0.000049518956],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995941,0.0000051941333,0.00010927434,0.00014391344,0.000057042038,0.000090484886],"domain_scores_gemma":[0.9997241,0.000076649965,0.000036607446,0.00008097802,0.00004564823,0.000036003465],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000006807157,0.00006690694,0.000069590635,0.000018362198,0.000012629802,0.000004942297,0.00006920365,0.00006539046,0.72298187],"category_scores_gemma":[0.0009281984,0.00007715586,0.00005825585,0.000055590514,0.000002622153,0.0000019924553,0.000024353094,0.00003123606,0.00005411597],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023326784,0.000009867565,0.000002605164,0.000087978995,0.000004606915,7.317272e-7,0.0000098865885,0.0022480472,0.008362733,7.755243e-7,0.98894054,0.00030890078],"study_design_scores_gemma":[0.00036941504,0.00013980421,0.0017962304,0.00022743254,0.0000026851121,5.5418985e-7,0.000011790079,0.0117538655,0.05786052,0.0000071636696,0.92771107,0.00011944535],"about_ca_topic_score_codex":6.56945e-7,"about_ca_topic_score_gemma":0.000003848609,"teacher_disagreement_score":0.72292775,"about_ca_system_score_codex":0.000005367797,"about_ca_system_score_gemma":0.00004448706,"threshold_uncertainty_score":0.31463248},"labels":[],"label_agreement":null},{"id":"W6976915841","doi":"10.60692/xg7jd-6j392","title":"Effects of CRISPR/Cas9 dosage on TICAM1 and RBL gene mutation rate, embryonic development, hatchability and fry survival in channel catfish","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Catfish; Microinjection; Embryo; Dose; Embryogenesis; Mutation; Yolk sac; Gene","score_opus":0.009366630118803685,"score_gpt":0.2299317037660267,"score_spread":0.22056507364722303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976915841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760468,0.00002397627,0.023358548,0.0000094119705,0.00015138953,0.00026281492,0.000010092455,0.000012502496,0.00012443952],"genre_scores_gemma":[0.999656,0.0000014327835,0.0001891905,0.00003224297,0.000044912234,0.000027243936,0.000022966604,0.0000066844877,0.00001928889],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993253,0.000042731775,0.00027258828,0.00014364545,0.000079854675,0.00013587592],"domain_scores_gemma":[0.99964833,0.000008137464,0.00008423824,0.00013880503,0.0000725924,0.000047865968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002868575,0.0001185383,0.00014178241,0.00008904128,0.000042684096,0.000025399146,0.000046061185,0.000097917065,7.9093246e-7],"category_scores_gemma":[0.00003445227,0.000109278815,0.000016480091,0.00006812512,0.000038074453,0.0000144238675,0.0000474437,0.000037400394,0.0000071603],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001990533,0.000092666836,0.5070509,0.017918592,0.0006003026,0.000027837605,0.30247194,0.0016243713,0.1549151,0.00020181717,0.00022618253,0.012879775],"study_design_scores_gemma":[0.0010300588,0.00016223082,0.4441871,0.00009238175,0.00001019701,0.000011352887,0.0012822318,0.00093788235,0.55206436,8.2963544e-7,0.0000677363,0.00015363898],"about_ca_topic_score_codex":0.0000062531076,"about_ca_topic_score_gemma":0.000003896007,"teacher_disagreement_score":0.39714926,"about_ca_system_score_codex":0.00001780624,"about_ca_system_score_gemma":0.000022229053,"threshold_uncertainty_score":0.44562608},"labels":[],"label_agreement":null},{"id":"W6977175607","doi":"10.6084/m9.figshare.13250793","title":"Additional file 7 of A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Drosophila (subgenus); RNA; Drosophila melanogaster; Key (lock); Base sequence","score_opus":0.02872874232592238,"score_gpt":0.2789533144687695,"score_spread":0.2502245721428471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6977175607","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028050315,0.000036241745,0.00011181776,0.000059462505,0.000008154807,0.0001451327,0.9988864,0.0000070232372,0.000465254],"genre_scores_gemma":[0.17164491,2.0933408e-7,0.00096436625,0.00014799046,0.0001300083,0.0003490444,0.8267027,0.00001123286,0.000049518956],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995941,0.0000051941333,0.00010927434,0.00014391344,0.000057042038,0.000090484886],"domain_scores_gemma":[0.9997241,0.000076649965,0.000036607446,0.00008097802,0.00004564823,0.000036003465],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000006807157,0.00006690694,0.000069590635,0.000018362198,0.000012629802,0.000004942297,0.00006920365,0.00006539046,0.72298187],"category_scores_gemma":[0.0009281984,0.00007715586,0.00005825585,0.000055590514,0.000002622153,0.0000019924553,0.000024353094,0.00003123606,0.00005411597],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023326784,0.000009867565,0.000002605164,0.000087978995,0.000004606915,7.317272e-7,0.0000098865885,0.0022480472,0.008362733,7.755243e-7,0.98894054,0.00030890078],"study_design_scores_gemma":[0.00036941504,0.00013980421,0.0017962304,0.00022743254,0.0000026851121,5.5418985e-7,0.000011790079,0.0117538655,0.05786052,0.0000071636696,0.92771107,0.00011944535],"about_ca_topic_score_codex":6.56945e-7,"about_ca_topic_score_gemma":0.000003848609,"teacher_disagreement_score":0.72292775,"about_ca_system_score_codex":0.000005367797,"about_ca_system_score_gemma":0.00004448706,"threshold_uncertainty_score":0.31463248},"labels":[],"label_agreement":null},{"id":"W6977292612","doi":"10.6084/m9.figshare.17084309.v1","title":"Additional file 6 of Revealing the composition of the eukaryotic microbiome of oyster spat by CRISPR-Cas Selective Amplicon Sequencing (CCSAS)","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Amplicon; 18S ribosomal RNA; Gene; Primer (cosmetics); Ribosomal RNA; DNA sequencing; Sequence analysis; Oligonucleotide","score_opus":0.010599809738456253,"score_gpt":0.24805160871174717,"score_spread":0.2374517989732909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6977292612","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009962362,0.00035897575,0.000056975605,0.000023106955,0.000019779436,0.00010306786,0.9892088,0.0000026299206,0.00026427774],"genre_scores_gemma":[0.56720954,0.0000022192878,0.00020921366,0.00006081076,0.00004562363,0.000045176006,0.43225634,0.000010396411,0.0001606646],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994773,0.00003729752,0.000172097,0.0001356967,0.000082543615,0.000095061994],"domain_scores_gemma":[0.99933964,0.00011243724,0.000121218014,0.00020954439,0.00020132592,0.0000158071],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000019294097,0.000079207144,0.00010482233,0.000012470651,0.000036313962,0.0000048928127,0.00012485748,0.00006592741,0.18079248],"category_scores_gemma":[0.00025987433,0.00005994246,0.00009609893,0.00010995699,0.000016799579,0.0000022631586,0.0000957128,0.00006345169,0.0000073132333],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002697638,0.000007762606,0.0000045930874,0.00007743633,0.000020055362,2.4248087e-7,0.00002767637,0.0001554092,0.48419973,3.206478e-7,0.515471,0.00003308314],"study_design_scores_gemma":[0.00008211847,0.000030978692,0.0016272061,0.0008330768,0.000010693813,0.000022093724,0.000057845005,0.00009233453,0.97061485,0.00000390147,0.026557744,0.0000671475],"about_ca_topic_score_codex":0.000005742808,"about_ca_topic_score_gemma":0.000008630902,"teacher_disagreement_score":0.55724716,"about_ca_system_score_codex":0.000014667072,"about_ca_system_score_gemma":0.0000801944,"threshold_uncertainty_score":0.81995636},"labels":[],"label_agreement":null},{"id":"W6980422390","doi":"","title":"Canada firm to develop UAE solar project","year":2012,"lang":"en","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"","score_opus":0.0068818429100498905,"score_gpt":0.26757588312981806,"score_spread":0.26069404021976816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6980422390","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002676666,0.004504218,0.017495597,0.00014009734,0.0010225038,0.0005699122,0.00014203737,0.000057842677,0.9758001],"genre_scores_gemma":[0.0043313205,0.00010259182,0.0060466765,0.00061401527,0.0008498596,0.000033562526,0.00020997568,0.00027765875,0.98753434],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992808,0.000007739023,0.00009710095,0.00023944613,0.000096054144,0.00027883303],"domain_scores_gemma":[0.99955237,0.0000018802411,0.000023310144,0.00029185292,0.000029587036,0.000101019425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000039645667,0.00019535399,0.00013295127,0.000045243127,0.000014832528,0.0000075607304,0.00015408914,0.00019228009,0.0005655938],"category_scores_gemma":[0.000029312987,0.00017977231,0.000024481817,0.00008910749,0.0000062309764,2.240169e-7,0.00010269294,0.000058250487,0.000032600947],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000020832772,0.0000050910444,0.00007326439,0.00002991351,0.00004479483,0.0000014828981,0.0000053092494,0.000005567881,0.0053475425,0.0000055306427,0.9925425,0.0019368966],"study_design_scores_gemma":[0.00006558055,0.000020499829,0.00011424412,0.00001600495,0.000010068914,0.0000053000504,0.000010360577,0.000001230919,0.025069684,1.4844201e-7,0.97441274,0.00027413646],"about_ca_topic_score_codex":0.27228522,"about_ca_topic_score_gemma":0.73841906,"teacher_disagreement_score":0.46613386,"about_ca_system_score_codex":0.000019291821,"about_ca_system_score_gemma":0.000694346,"threshold_uncertainty_score":0.7330902},"labels":[],"label_agreement":null},{"id":"W6981131708","doi":"","title":"Différence sur le plan des formes de motivation entre les étudiants de première génération et les autres à s'inscrire à un programme universitaire de deuxième ou troisième cycle","year":2018,"lang":"fr","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Population; Public investment; Cycle of poverty; Context (archaeology)","score_opus":0.012126861192064147,"score_gpt":0.23961747800032782,"score_spread":0.22749061680826366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6981131708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83022666,0.0022500409,0.122782715,0.0007543962,0.00010105456,0.0005039329,0.00007775607,0.00010354829,0.043199874],"genre_scores_gemma":[0.93460566,0.0013314569,0.010749014,0.000024897503,0.0003003141,0.00002575452,0.00037235365,0.0001212368,0.052469287],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998235,0.00012400019,0.0002480155,0.0005116533,0.00014163734,0.0007397175],"domain_scores_gemma":[0.99919647,0.000045230878,0.00014184142,0.00028909318,0.00011785217,0.00020949762],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018585437,0.00043406454,0.0002686867,0.00009713273,0.000264729,0.00008701152,0.00030645987,0.00074635836,0.00049869687],"category_scores_gemma":[0.00016354992,0.00045988374,0.00016001056,0.0001235018,0.00021007305,0.000024293267,0.0001260029,0.00017689292,0.000011321397],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019724146,0.0008225718,0.42550182,0.0011206233,0.0008460081,0.00004371002,0.0022998613,0.0046177544,0.28885838,0.0074833976,0.008950417,0.25925818],"study_design_scores_gemma":[0.0045689624,0.0017585844,0.1801423,0.0016284833,0.0005483696,0.0002105179,0.013369928,0.013694148,0.6112461,0.0015476445,0.16859177,0.002693166],"about_ca_topic_score_codex":0.0008457127,"about_ca_topic_score_gemma":0.0074384036,"teacher_disagreement_score":0.32238773,"about_ca_system_score_codex":0.0001677266,"about_ca_system_score_gemma":0.00043086917,"threshold_uncertainty_score":0.9997853},"labels":[],"label_agreement":null},{"id":"W6986233576","doi":"","title":"Optimisation des alliages thermoélectriques de type N à base de tellurure de bismuth pour des applications de génération d'énergie","year":2008,"lang":"fr","type":"other","venue":"PolyPublie (École Polytechnique de Montréal)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bismuth; Bismuth telluride; Thermoelectric effect; Seebeck coefficient; Semiconductor materials; Base (topology)","score_opus":0.009879505124446152,"score_gpt":0.25792038553932134,"score_spread":0.24804088041487518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6986233576","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11389074,0.025972554,0.8541665,0.00064749236,0.00004947784,0.0008838153,0.00007316006,0.00026715905,0.0040490995],"genre_scores_gemma":[0.50181085,0.03978294,0.42183435,0.0008121943,0.0010569845,0.0010950156,0.0003966762,0.0004630052,0.03274798],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99714506,0.00028868558,0.0004736243,0.0006770836,0.00019375826,0.0012218057],"domain_scores_gemma":[0.9981348,0.00008036976,0.0002585501,0.0008250201,0.00020765654,0.00049363694],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005868483,0.00067118235,0.0004165448,0.0003146083,0.00037402957,0.00014978962,0.0005484563,0.0013477368,0.00022466273],"category_scores_gemma":[0.00028430362,0.00076619745,0.00027240574,0.0003998351,0.0002803643,0.000022559905,0.00012932984,0.000520995,0.000020428237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107713175,0.00032754545,0.00984607,0.000273401,0.00023890186,0.000043740674,0.0008061231,0.05887961,0.8775997,0.0012276145,0.004679473,0.04597009],"study_design_scores_gemma":[0.000552703,0.00032257003,0.012213888,0.00026634938,0.000244031,0.0006187974,0.00021484043,0.06451393,0.87247574,0.0023530421,0.04511884,0.001105282],"about_ca_topic_score_codex":0.0042589824,"about_ca_topic_score_gemma":0.0038950548,"teacher_disagreement_score":0.43233216,"about_ca_system_score_codex":0.0011775419,"about_ca_system_score_gemma":0.0014324532,"threshold_uncertainty_score":0.99994874},"labels":[],"label_agreement":null},{"id":"W6986668440","doi":"","title":"The process of marital disillusion/dissolution, the shifting life course of contemporary women","year":2000,"lang":"en","type":"other","venue":"Library and Archives Canada (Government of Canada)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Life course approach; Process (computing); Course (navigation); Work (physics); Qualitative research","score_opus":0.001786488377300797,"score_gpt":0.17323724721390624,"score_spread":0.17145075883660543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6986668440","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07252317,0.023162339,0.00010800564,0.0015826558,0.0002824526,0.0004886542,0.0012794358,0.000008141539,0.90056515],"genre_scores_gemma":[0.9562432,0.0008020883,0.000030436519,0.00012611804,0.00008899622,0.000009032451,0.000023570592,0.00005424096,0.042622317],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99891424,0.000031350966,0.0002405914,0.0001508586,0.00049014966,0.00017282554],"domain_scores_gemma":[0.9994164,0.000052185616,0.00019767013,0.0002355442,6.4779766e-7,0.000097524375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001452925,0.00015297138,0.00019369971,0.000008322415,0.0000779131,0.0000057044635,0.00026077006,0.00004581086,0.000025408091],"category_scores_gemma":[0.000004520777,0.000101194346,0.000027324118,0.00003568892,0.00014823921,0.000003795015,0.00010343527,0.00007636607,4.5667972e-10],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005002594,0.00044893788,0.0651316,0.0063668983,0.005320712,0.0000635056,0.0023571954,0.0022436564,0.30725688,0.011964274,0.5362656,0.05757815],"study_design_scores_gemma":[0.0007949263,0.00028720207,0.016898165,0.00049476494,0.00006287312,0.0000068596546,0.009185569,0.00046992404,0.15399298,0.0002058774,0.81701857,0.0005822963],"about_ca_topic_score_codex":0.0007783114,"about_ca_topic_score_gemma":0.0062814364,"teacher_disagreement_score":0.88372004,"about_ca_system_score_codex":0.0000010178137,"about_ca_system_score_gemma":0.001212174,"threshold_uncertainty_score":0.41265854},"labels":[],"label_agreement":null},{"id":"W6994102814","doi":"","title":"","year":2022,"lang":"en","type":"other","venue":"Directory of Open access Books (OAPEN Foundation)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Consumption (sociology); Process (computing); Identification (biology); Work (physics)","score_opus":0.03681802450671344,"score_gpt":0.4184933633819219,"score_spread":0.38167533887520844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6994102814","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007767963,0.0016162901,0.0025610416,0.00010164156,0.0013077293,0.0027368686,0.000038489416,0.00012382655,0.9837462],"genre_scores_gemma":[0.053196702,0.0012833363,0.0018692232,0.0005340929,0.0007687462,0.0010865475,0.0060895383,0.0014382671,0.9337335],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996947,0.000189526,0.00070325483,0.0011905967,0.00051138125,0.0004582276],"domain_scores_gemma":[0.997353,0.00003433571,0.00078548933,0.0015365502,0.0001125445,0.0001780456],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00048426856,0.00064028276,0.000801899,0.0004226517,0.00022061789,0.0007433326,0.005265401,0.00019822973,0.029745111],"category_scores_gemma":[0.00014476627,0.0007433506,0.00025812638,0.00025592744,0.00018312414,0.000047146375,0.0058302074,0.00028009427,0.000043785043],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010791335,0.0010397749,0.040623855,0.001506814,0.003957427,0.000051923176,0.00024108207,0.0024497928,0.20650549,0.004900696,0.48315427,0.25448975],"study_design_scores_gemma":[0.001047243,0.00013478559,0.0051171877,0.00008246153,0.00008547008,0.000008770878,0.00005448844,0.000012310553,0.02386226,0.000053704905,0.96870595,0.00083534064],"about_ca_topic_score_codex":0.001822057,"about_ca_topic_score_gemma":0.0019970085,"teacher_disagreement_score":0.4855517,"about_ca_system_score_codex":0.0000704669,"about_ca_system_score_gemma":0.0003992726,"threshold_uncertainty_score":0.99950176},"labels":[],"label_agreement":null},{"id":"W6995667953","doi":"","title":"The Path From &lt;i&gt;Rodriguez&lt;/i&gt; to Bill C-14 and Beyond: Lessons About MAiD Law Reform in Canada","year":2021,"lang":"en","type":"article","venue":"eYLS (Yale Law School)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Law reform; Public law; Path (computing); Common law; Social reform; Path dependency","score_opus":0.0055660015222037075,"score_gpt":0.23602612346335616,"score_spread":0.23046012194115245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6995667953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9632435,0.014545307,0.00029825032,0.0032648311,0.0007012506,0.0002532387,0.0002970351,0.00002110778,0.017375512],"genre_scores_gemma":[0.9945288,0.0009537193,0.000770106,0.0018415913,0.00024364331,0.00003958344,0.000141684,0.000037463313,0.0014434371],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984798,0.00004938202,0.00028634002,0.0005065081,0.00021048068,0.00046752213],"domain_scores_gemma":[0.9989054,0.00003341656,0.000041429135,0.00065787416,0.00007728693,0.00028459358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016210652,0.00022876574,0.00021692405,0.000017013457,0.00018727143,0.00008477174,0.00025946822,0.00013130977,0.000040817813],"category_scores_gemma":[0.00006466067,0.00017620763,0.00006036232,0.0001282947,0.000059087313,0.000006789973,0.0002485364,0.00018027658,0.000013108114],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006917071,0.000052531177,0.0012151968,0.000032124048,0.000120534554,0.00013226806,0.00015167343,0.00065483566,0.9610917,0.023195604,0.008251276,0.005033081],"study_design_scores_gemma":[0.00059569546,0.000057332887,0.009675145,0.000041741005,0.000019126343,0.000016829714,0.00015752105,0.000064908825,0.14436601,0.00040765016,0.84422755,0.00037046292],"about_ca_topic_score_codex":0.21874516,"about_ca_topic_score_gemma":0.96919346,"teacher_disagreement_score":0.8359763,"about_ca_system_score_codex":0.00015761434,"about_ca_system_score_gemma":0.00037154372,"threshold_uncertainty_score":0.7864573},"labels":[],"label_agreement":null},{"id":"W6995902642","doi":"","title":"Podcast 32 Interview With Novelist Andre Rome","year":2013,"lang":"en","type":"other","venue":"Bulletin of Miscellaneous Information (Royal Gardens Kew)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Miracle; Quarter (Canadian coin); State (computer science); Creole language; Presentation (obstetrics)","score_opus":0.004505527663287615,"score_gpt":0.19967006783274066,"score_spread":0.19516454016945303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6995902642","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017359605,0.0014500078,0.000029443832,0.000064423824,0.00013478824,0.00029953953,0.00009744578,0.000043200096,0.99770755],"genre_scores_gemma":[0.0019064511,0.00045363232,0.0011930565,0.00017764476,0.00020132866,0.000018411796,0.00038332038,0.00012490276,0.9955413],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990755,0.000022242692,0.0003159855,0.00019420116,0.00017393612,0.00021817264],"domain_scores_gemma":[0.99923354,0.000007388125,0.00021342131,0.00036661193,0.00008847159,0.000090562564],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000076388926,0.0002890092,0.0002743781,0.000038606697,0.000023646246,0.000034265915,0.00022874633,0.0003023093,0.09710535],"category_scores_gemma":[0.000021196236,0.00025442702,0.00009782054,0.000005030376,0.000071654475,1.43228815e-8,0.00009142638,0.00012815428,0.0022045027],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022886295,0.000020140842,0.0000020042953,0.0004120024,0.00008019362,0.000004093293,0.000019346422,0.00020347949,0.000031439155,0.0000034838638,0.99711245,0.002088466],"study_design_scores_gemma":[0.00040576933,0.00025370688,0.000019248713,0.00024175599,0.000035621244,0.000105845065,0.00003814987,0.000010103217,0.0002461041,3.236892e-7,0.9983322,0.00031117242],"about_ca_topic_score_codex":0.0006611747,"about_ca_topic_score_gemma":0.00073790795,"teacher_disagreement_score":0.09490085,"about_ca_system_score_codex":0.000009761292,"about_ca_system_score_gemma":0.000019152361,"threshold_uncertainty_score":0.9999908},"labels":[],"label_agreement":null},{"id":"W7008779141","doi":"","title":"Crosscurrents: Spring 2011","year":2011,"lang":"en","type":"article","venue":"Sound Ideas (University of Puget Sound)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of Massachusetts Amherst; Massachusetts Cultural Council","keywords":"","score_opus":0.015917531254984952,"score_gpt":0.24755582808211476,"score_spread":0.2316382968271298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7008779141","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.931644,0.0006347252,0.06377154,0.00000968091,0.00020596359,0.00007160793,0.0000124499675,0.000022038883,0.0036279482],"genre_scores_gemma":[0.99632716,0.0000980037,0.0023846668,0.000014796663,0.00006650651,2.1480548e-7,0.000016297803,0.000013854031,0.0010785061],"study_design_codex":"observational","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99932176,0.000016508991,0.00009147704,0.00024891456,0.00010247108,0.0002188723],"domain_scores_gemma":[0.999459,0.000004332946,0.00005986935,0.00031401584,0.000071176015,0.0000915677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099221426,0.00012079309,0.0001274417,0.000057497717,0.00011455613,0.000008942819,0.0002693286,0.000106060936,0.0002753379],"category_scores_gemma":[0.0000149880525,0.00015580101,0.0001268588,0.000057620673,0.00013018839,0.000009571848,0.00016574062,0.00007522948,0.000070873626],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011294787,0.0012933303,0.5715179,0.0007510796,0.0017830081,0.00012784984,0.013229499,0.0012716022,0.10892109,0.28475124,0.012630211,0.0025937408],"study_design_scores_gemma":[0.0030463943,0.0006852256,0.17921984,0.00005680722,0.000218138,0.000039325932,0.005440507,0.00025838558,0.006787945,0.78159904,0.021323947,0.0013244365],"about_ca_topic_score_codex":0.00030480712,"about_ca_topic_score_gemma":0.00028202293,"teacher_disagreement_score":0.4968478,"about_ca_system_score_codex":0.000012787972,"about_ca_system_score_gemma":0.000026548885,"threshold_uncertainty_score":0.6353381},"labels":[],"label_agreement":null},{"id":"W7026905978","doi":"","title":"Balancing Biomedical Progress Against Reproductive Justice in the Case of Human Germline Genome Editing with CRISPR-Cas9","year":2021,"lang":"en","type":"dissertation","venue":"QSpace (Queen's University Library)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Bioethics; Economic Justice; Perspective (graphical); Genome editing; Germline; Premise; Human enhancement; Public policy; Reproductive technology; Social issues","score_opus":0.004322327026695866,"score_gpt":0.24107047166394335,"score_spread":0.2367481446372475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7026905978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952249,0.00037060172,0.00027874723,0.0017564556,0.00020135997,0.00033692594,0.00006700874,0.000026435528,0.0017375977],"genre_scores_gemma":[0.98878336,0.00025629438,0.0013658821,0.00004367262,0.00061904965,0.0000035506953,0.0033723107,0.000051228802,0.005504666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863005,0.0001163867,0.00019941319,0.00060141383,0.00017229006,0.00028042772],"domain_scores_gemma":[0.99909556,0.000024346564,0.00019110515,0.00051151554,0.0000960451,0.00008142212],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001030438,0.00026937903,0.00029405774,0.00019924666,0.00014019012,0.000031214357,0.00031477748,0.00027893975,0.000018930223],"category_scores_gemma":[0.00004425141,0.00024700275,0.00010038364,0.0004442063,0.00010743015,0.00002188837,0.00011751666,0.0003673572,5.634277e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006368881,0.0065690074,0.03378737,0.032809086,0.0064262217,0.19994263,0.09428223,0.009747656,0.4046842,0.00303129,0.18567742,0.01667402],"study_design_scores_gemma":[0.005414235,0.0027652718,0.033775765,0.002593796,0.002128932,0.0003405061,0.33036318,0.000105626794,0.5013373,0.000035316712,0.11742137,0.0037186702],"about_ca_topic_score_codex":0.0004877414,"about_ca_topic_score_gemma":0.0003104342,"teacher_disagreement_score":0.23608096,"about_ca_system_score_codex":0.000022532153,"about_ca_system_score_gemma":0.00018060736,"threshold_uncertainty_score":0.9999982},"labels":[],"label_agreement":null},{"id":"W7033202238","doi":"","title":"20 Poems By Alireza Roshan","year":2017,"lang":"en","type":"other","venue":"Bulletin of Miscellaneous Information (Royal Gardens Kew)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Poetry; Conversation; Reading (process); Painting; Persian","score_opus":0.004386639308324059,"score_gpt":0.21812003359210347,"score_spread":0.2137333942837794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7033202238","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000042121,0.0022405514,0.000008368164,0.000051093502,0.00027797674,0.00020419389,0.00030902418,0.000044994416,0.9968217],"genre_scores_gemma":[0.0010779895,0.0008700709,0.00033524493,0.000117174044,0.00028399867,0.000010918768,0.00091674435,0.00011672692,0.99627113],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99909514,0.000017854385,0.00026723545,0.00019915978,0.00018431405,0.0002362868],"domain_scores_gemma":[0.999014,0.0000070511214,0.000292034,0.00053407974,0.000056641904,0.00009618808],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00008916752,0.0002719173,0.00025028657,0.000027320604,0.000051257928,0.000038813545,0.00035426096,0.00044026872,0.04852562],"category_scores_gemma":[0.000054552493,0.00028360414,0.00013051085,0.0000017358071,0.000081328355,9.560206e-9,0.000105187726,0.00012060505,0.0013940255],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002081633,0.000015798589,0.0000017242464,0.00015826618,0.00006348141,0.0000027369676,0.000012670242,0.000100214784,0.0001840327,0.000001165308,0.997861,0.0015780729],"study_design_scores_gemma":[0.0003333782,0.000114036404,0.0000020159007,0.0000994279,0.000029004179,0.000027473603,0.000011945196,0.000006729171,0.0015177963,7.7756e-7,0.99754804,0.0003093511],"about_ca_topic_score_codex":0.0011820119,"about_ca_topic_score_gemma":0.000756123,"teacher_disagreement_score":0.047131594,"about_ca_system_score_codex":0.000008946023,"about_ca_system_score_gemma":0.000019555104,"threshold_uncertainty_score":0.9999616},"labels":[],"label_agreement":null},{"id":"W7033945098","doi":"","title":"A song to \"The beautiful Goddess\": Text, ritual, and devotion in the Â«Apirami AntatiÂ»","year":2010,"lang":"en","type":"other","venue":"Library and Archives Canada (Government of Canada)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nucleofection; Fusible alloy; Circumstantial evidence; Gestational period; Pretext; Hyporeflexia","score_opus":0.0019274387254593407,"score_gpt":0.17439282408978196,"score_spread":0.17246538536432263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7033945098","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10268461,0.008980082,0.0015465207,0.012047536,0.0007782396,0.0012761955,0.0007517169,0.00001608511,0.87191904],"genre_scores_gemma":[0.92407995,0.0006885228,0.00088881265,0.0021865466,0.00029740168,0.000029108445,0.000039576666,0.000104847015,0.071685255],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99903935,0.00003493549,0.00012886777,0.00020997244,0.00040911333,0.00017775032],"domain_scores_gemma":[0.9996082,0.000032763186,0.000054875054,0.00022128274,2.5195865e-7,0.000082628125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000015784344,0.00015939979,0.00013249111,0.000018372617,0.000056568944,0.000018893219,0.00020661154,0.0000605665,0.000018772225],"category_scores_gemma":[0.0000038864505,0.000114983544,0.00001584097,0.000040641025,0.000050608214,0.000003596536,0.00010377787,0.00014280216,2.7579556e-9],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006398284,0.00012903212,0.020699518,0.0011454107,0.00042819022,0.00014867676,0.0009893673,0.00042075355,0.43839413,0.015783314,0.39885873,0.12236306],"study_design_scores_gemma":[0.00022600885,0.00008760107,0.015568364,0.00008990529,0.000018552008,0.000012050867,0.00096470234,0.00012304529,0.025834963,0.00004149662,0.9567891,0.00024424266],"about_ca_topic_score_codex":0.0025151316,"about_ca_topic_score_gemma":0.24809411,"teacher_disagreement_score":0.82139534,"about_ca_system_score_codex":0.000001219276,"about_ca_system_score_gemma":0.0002755149,"threshold_uncertainty_score":0.7656262},"labels":[],"label_agreement":null},{"id":"W7033956460","doi":"","title":"Seismic evaluation of existing steel braced frames designed in accordance with the 1980 Canadian code requirements using nonlinear time history analysis","year":2013,"lang":"en","type":"other","venue":"PolyPublie (École Polytechnique de Montréal)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Nonlinear system; Code (set theory); Seismic analysis; Steel frame; Frame (networking)","score_opus":0.02263135780606627,"score_gpt":0.2867081812573709,"score_spread":0.2640768234513046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7033956460","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.39379624,0.026282338,0.55851203,0.00038567357,0.00020068014,0.004022887,0.00045125734,0.00017891962,0.01616997],"genre_scores_gemma":[0.85994905,0.00034221826,0.07260147,0.0007444587,0.0003300704,0.00062607176,0.0008259984,0.0006120105,0.06396863],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9982534,0.00016775275,0.0003357623,0.00044511782,0.00035791958,0.00044002585],"domain_scores_gemma":[0.9985792,0.000018432705,0.0003452782,0.0007805652,0.00014036034,0.0001361843],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006937739,0.00033576804,0.00040234646,0.0006527047,0.000051297797,0.00002688422,0.0003792298,0.0003980948,0.00011607785],"category_scores_gemma":[0.00009036701,0.00029896232,0.00012239102,0.00039997487,0.00008192827,0.0000073744027,0.000070869886,0.00022877264,0.000003271859],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000116665105,0.00017847787,0.017093511,0.00017713687,0.0020349585,0.000017480785,0.00040481656,0.5356921,0.39478162,0.00007904629,0.041892506,0.007531673],"study_design_scores_gemma":[0.0007250896,0.00012237263,0.004763593,0.0002058863,0.0009293812,0.000012202786,0.000095058145,0.9447605,0.015594558,0.0000060985785,0.032085117,0.0007001418],"about_ca_topic_score_codex":0.2133424,"about_ca_topic_score_gemma":0.34365723,"teacher_disagreement_score":0.48591056,"about_ca_system_score_codex":0.00061977183,"about_ca_system_score_gemma":0.00093921646,"threshold_uncertainty_score":0.99994624},"labels":[],"label_agreement":null},{"id":"W7036280516","doi":"","title":"Aviary Specialization Changes","year":2020,"lang":"en","type":"other","venue":"OSF Preprints (OSF Preprints)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Urbanization; Habitat; Metropolitan area; Population; Index (typography); Climate change; Population decline; Seasonality","score_opus":0.008813172654362935,"score_gpt":0.26755725882398007,"score_spread":0.25874408616961714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7036280516","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00013176698,0.000048824393,0.015867138,0.00019108763,0.0005537911,0.00055883406,0.000052578034,0.00012737741,0.9824686],"genre_scores_gemma":[0.0018814015,0.0018200884,0.0012855267,0.00025456652,0.0014845085,0.00009574461,0.00041826934,0.0003964307,0.99236345],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99753386,0.00012357878,0.00023603337,0.0016018149,0.0002122503,0.00029244833],"domain_scores_gemma":[0.9976849,0.000015676993,0.00015867017,0.0019369116,0.00003259811,0.00017123364],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00041856026,0.00035962526,0.00031780486,0.00010722439,0.0000433376,0.000043306747,0.0006256804,0.00052592927,0.33550933],"category_scores_gemma":[0.000461895,0.00043048096,0.00014123802,0.00010752335,0.00006553031,0.000002001193,0.00086258585,0.00022383784,0.27429402],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030567735,0.000055629007,0.0005492001,0.00017946049,0.00019747595,0.000012187025,0.00010468326,0.00020808741,0.05984267,0.00008743688,0.9283978,0.010334838],"study_design_scores_gemma":[0.00023974407,0.0000017106463,0.00030690868,0.000084092346,0.0000516338,0.000011431259,0.000016670552,0.00005704595,0.0498645,0.000051416482,0.9489168,0.00039804433],"about_ca_topic_score_codex":0.00006998508,"about_ca_topic_score_gemma":0.00022157689,"teacher_disagreement_score":0.06121531,"about_ca_system_score_codex":0.000029377694,"about_ca_system_score_gemma":0.00007196726,"threshold_uncertainty_score":0.9998147},"labels":[],"label_agreement":null},{"id":"W7037169837","doi":"","title":"The effects of a dietary or «in ovo» exposure to the pentabrominated diphenyl ether mixture, DE-71, on retinol and thyroid hormones in captive American kestrels («Falco sparverius»)","year":2010,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Wildlife Research Center; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Retinol; Reproduction; Thyroid hormones; Hormone; Thyroid; Diphenyl ether; In ovo","score_opus":0.004978828299782741,"score_gpt":0.2587351388296444,"score_spread":0.25375631052986164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7037169837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959507,0.0016887196,4.4254318e-7,0.000035572597,0.00033673097,0.0009021573,0.00015840646,0.000015073816,0.0009121735],"genre_scores_gemma":[0.9966574,0.0014587665,0.00020220863,0.00012226793,0.000047629255,0.00022977174,0.00018994765,0.00009935767,0.0009926801],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779147,0.00028992957,0.0004693951,0.00066499185,0.0002702419,0.00051394524],"domain_scores_gemma":[0.99858844,0.00029199812,0.00024480323,0.00063318573,0.00009953659,0.00014204055],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050028233,0.0005033183,0.00046467784,0.00014156025,0.00022100592,0.000034718123,0.00047476418,0.0004908113,0.000005613453],"category_scores_gemma":[0.0009675548,0.00034236428,0.0001426471,0.00033621097,0.00010434134,0.000008777547,0.00012258423,0.0009866148,0.0000041281014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011747638,0.00010276637,0.00032379178,0.00015271948,0.00010506471,0.000035695404,0.000081186576,0.00009902848,0.9509192,0.00013653767,0.00001152936,0.04685771],"study_design_scores_gemma":[0.0010732176,0.002354734,0.101730205,0.00042460323,0.00009940107,0.000019938529,0.0009327614,0.000013796869,0.8869299,0.00020235142,0.005533362,0.0006857083],"about_ca_topic_score_codex":0.00074930803,"about_ca_topic_score_gemma":0.02046097,"teacher_disagreement_score":0.10140641,"about_ca_system_score_codex":0.00006979397,"about_ca_system_score_gemma":0.000042634398,"threshold_uncertainty_score":0.99990284},"labels":[],"label_agreement":null},{"id":"W7037463963","doi":"","title":"Econometric analysis of compliance to social norms and socially desired behaviors","year":2024,"lang":"en","type":"other","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Social capital; Panel survey; Econometric analysis; Proxy (statistics)","score_opus":0.020378991971047318,"score_gpt":0.34454522022847595,"score_spread":0.32416622825742863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7037463963","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08720433,0.022258898,0.047694225,0.00037136584,0.0011042602,0.0011960564,0.0019907255,0.00019495038,0.8379852],"genre_scores_gemma":[0.29590702,0.00037625316,0.00455085,0.000102987025,0.00039580636,0.000025415355,0.0002734137,0.00030820703,0.69806004],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994049,0.0000052626388,0.00013655963,0.00027810957,0.00005730135,0.00011785568],"domain_scores_gemma":[0.9997592,0.000002086106,0.000040980307,0.00013339764,0.000016452574,0.000047893198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043645625,0.00013788344,0.00027845358,0.000445088,0.000010866612,0.000013095193,0.000092729475,0.00019152531,0.00026118546],"category_scores_gemma":[0.000006675161,0.0001353453,0.00013746473,0.00043677862,0.000028827648,2.803847e-7,0.000081766506,0.000039453014,0.000014294132],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056585744,0.00022570945,0.0066105365,0.0015824734,0.014618641,0.000013736658,0.00055015786,0.00054529426,0.16158402,0.001744269,0.77375305,0.038715556],"study_design_scores_gemma":[0.00091609685,0.0005737397,0.05502748,0.00020132477,0.008688738,0.00000521621,0.00032456822,0.0003925031,0.03171967,0.00011908987,0.8994785,0.0025530625],"about_ca_topic_score_codex":0.00007280054,"about_ca_topic_score_gemma":0.0007051802,"teacher_disagreement_score":0.20870268,"about_ca_system_score_codex":0.000006832138,"about_ca_system_score_gemma":0.000027469894,"threshold_uncertainty_score":0.55192214},"labels":[],"label_agreement":null},{"id":"W7039203935","doi":"","title":"L´origen de la multicel·lularitat en animals: una aproximació genòmica = The origin of multicellularity in animals: a genomic approach","year":2017,"lang":"ca","type":"dissertation","venue":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Directorate for Biological Sciences; Generalitat Valenciana; Joint Genome Institute; National Science Foundation; Canadian Institutes of Health Research; Comunidad de Madrid; Tula Foundation; European Regional Development Fund; Broad Institute; Gordon and Betty Moore Foundation; Ministerio de Economía y Competitividad; Generalitat de Catalunya","keywords":"Genome; Biological evolution; Gens","score_opus":0.01712052366443753,"score_gpt":0.30017071540954937,"score_spread":0.2830501917451118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7039203935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9528605,0.009619913,0.0057572727,0.0010070867,0.00082579517,0.001973106,0.00026804677,0.00008531724,0.027602963],"genre_scores_gemma":[0.98880297,0.0013874845,0.0071813185,0.000026361673,0.00071680197,0.00038471477,0.0010421018,0.00014966463,0.00030858698],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99418515,0.0012223691,0.0013418397,0.001425697,0.00071293383,0.001112033],"domain_scores_gemma":[0.996322,0.00031821203,0.0009762083,0.0014904927,0.0004766146,0.00041649895],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002202915,0.0009889082,0.0010051455,0.00043203737,0.0007656069,0.00034895467,0.0018157698,0.0020702512,0.000017935514],"category_scores_gemma":[0.0013931995,0.00093487086,0.0005703147,0.0003665265,0.00010700463,0.000039459133,0.00036984897,0.0015178886,0.0000045622187],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001364986,0.0014265664,0.002684293,0.0019953616,0.000854744,0.00019941275,0.007509031,0.0021417544,0.86796314,0.11137598,0.00007257991,0.0024121706],"study_design_scores_gemma":[0.00550901,0.0004148957,0.05789682,0.0009786693,0.00086722424,0.001250784,0.0058661504,0.015606832,0.17538756,0.00028933445,0.7332878,0.0026448993],"about_ca_topic_score_codex":0.0000343509,"about_ca_topic_score_gemma":0.00036225078,"teacher_disagreement_score":0.7332153,"about_ca_system_score_codex":0.00060635235,"about_ca_system_score_gemma":0.0014026968,"threshold_uncertainty_score":0.9993102},"labels":[],"label_agreement":null},{"id":"W7039710329","doi":"","title":"Mental health and work","year":2025,"lang":"et","type":"dissertation","venue":"DSpace repository (University of Tartu)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Work (physics); Mental health; Baseline (sea); Quarter (Canadian coin); Behavioral analysis","score_opus":0.003774744286008134,"score_gpt":0.23719059120650185,"score_spread":0.23341584692049372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7039710329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9662444,0.025067214,0.0010812625,0.000731881,0.0011236583,0.0003987891,0.000066848435,0.000018480689,0.0052674403],"genre_scores_gemma":[0.89254415,0.007998546,0.0017982012,0.00005456766,0.00011996332,5.328869e-7,0.0013399934,0.000026598675,0.09611742],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990613,0.00005394763,0.00013850369,0.0004096781,0.00013126028,0.00020529826],"domain_scores_gemma":[0.9992762,0.000009505379,0.00018827582,0.0002890368,0.00007215274,0.0001647918],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007031105,0.00021432214,0.00030861743,0.00007728532,0.00028483063,0.000015430833,0.00017064005,0.00028873215,0.00000917401],"category_scores_gemma":[0.000009315537,0.00030227064,0.00013922578,0.00011099198,0.00006513434,0.0000045608867,0.000112232636,0.00015103028,0.000001609522],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003364043,0.00065650797,0.0314601,0.007897117,0.0029249422,0.000114249684,0.03428665,0.00085792574,0.71864974,0.00017826578,0.16139002,0.03822044],"study_design_scores_gemma":[0.004998937,0.0026381637,0.04137372,0.004402117,0.00069925137,0.0000872273,0.10539263,0.00061291945,0.19939752,0.000015167776,0.63774,0.0026423517],"about_ca_topic_score_codex":0.000326229,"about_ca_topic_score_gemma":0.0002342541,"teacher_disagreement_score":0.5192522,"about_ca_system_score_codex":0.00004210233,"about_ca_system_score_gemma":0.00032331466,"threshold_uncertainty_score":0.99994296},"labels":[],"label_agreement":null},{"id":"W7071953628","doi":"","title":"Trade implications of gene-edited wheat under different regulatory scenarios","year":2022,"lang":"en","type":"dissertation","venue":"University Library (University of Saskatchewan)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Competitor analysis; Commodity; Sustainability; Climate change; Global climate; Food security; Key (lock); Protectionism","score_opus":0.005057268816388664,"score_gpt":0.1995157983708109,"score_spread":0.19445852955442225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7071953628","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99551797,0.00045956543,0.0009727394,0.0002551215,0.00020438925,0.00023142729,0.0005555308,0.000039000406,0.0017642757],"genre_scores_gemma":[0.9683007,0.0003835835,0.00077756855,0.000024155655,0.000051728155,1.4427653e-7,0.005755317,0.000035607354,0.024671199],"study_design_codex":"bench_or_experimental","study_design_gemma":"qualitative","domain_scores_codex":[0.99902,0.000055743916,0.00014121513,0.00040880247,0.00018158049,0.0001926497],"domain_scores_gemma":[0.9991254,0.000015958049,0.00020333944,0.000502827,0.000033729288,0.000118710916],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000028974624,0.00023436148,0.00032385212,0.00024803964,0.0001850628,0.0000052928667,0.0005921831,0.0003205415,0.0005650252],"category_scores_gemma":[0.0000019677504,0.00033830767,0.00030005677,0.00022930437,0.000099573364,0.000025171039,0.00017836834,0.00021001502,0.0000012275498],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014738417,0.00068394357,0.00806875,0.0008721071,0.0013629871,0.000041947842,0.022600276,0.004518298,0.94073176,0.00039427186,0.016399045,0.0028527891],"study_design_scores_gemma":[0.0028803477,0.00062993553,0.26931107,0.00015983389,0.0008452523,0.000013661987,0.4021503,0.000105590174,0.27398866,0.00016396752,0.048340425,0.0014109696],"about_ca_topic_score_codex":0.00015310157,"about_ca_topic_score_gemma":0.0006350216,"teacher_disagreement_score":0.6667431,"about_ca_system_score_codex":0.00004237771,"about_ca_system_score_gemma":0.00028619857,"threshold_uncertainty_score":0.9999069},"labels":[],"label_agreement":null},{"id":"W7084238284","doi":"","title":"Dual femtosecond pumping supercontinuum generation in a highly doped silica glass integrated waveguide","year":2024,"lang":"en","type":"article","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Supercontinuum; Femtosecond; Doping; Waveguide; Silica glass; Reflectivity; Sapphire","score_opus":0.008931982958122246,"score_gpt":0.24754123202921233,"score_spread":0.23860924907109007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7084238284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.935534,0.0018331651,0.054311343,0.0018523781,0.00017168165,0.00016712343,0.000019456293,0.00006589798,0.0060449764],"genre_scores_gemma":[0.9899991,0.00024123926,0.0042296373,0.00005505549,0.000064908134,0.000030306537,0.00057571067,0.000029628092,0.0047744038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832,0.00058809976,0.00029580112,0.00044247106,0.00011792396,0.00023572381],"domain_scores_gemma":[0.99896675,0.000090431844,0.000033597295,0.00053354277,0.00029755812,0.00007810688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013777764,0.00016166417,0.00013308854,0.000111226436,0.000078872916,0.00019066311,0.00021711692,0.0001314166,0.000053597374],"category_scores_gemma":[0.0003846355,0.00016728244,0.00007960519,0.00027500372,0.00005473439,0.000014613982,0.00014133623,0.00016672476,0.000017049277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000059907607,0.000054138636,0.0002720182,0.000028989252,0.000023935028,0.00000558373,0.000971056,0.00011365606,0.98392487,0.0021737644,0.0008576937,0.011568293],"study_design_scores_gemma":[0.00027888388,9.52384e-7,0.0010621047,0.00017199316,0.000009523968,0.000016154476,0.00008293867,0.037442334,0.9090412,0.000042014177,0.05165559,0.00019631188],"about_ca_topic_score_codex":0.00026728,"about_ca_topic_score_gemma":0.0046184785,"teacher_disagreement_score":0.074883685,"about_ca_system_score_codex":0.000039311315,"about_ca_system_score_gemma":0.00011027706,"threshold_uncertainty_score":0.682158},"labels":[],"label_agreement":null},{"id":"W7087114786","doi":"10.52398/gjsd.2025.v5.i3.pp109-129","title":"Mapping Hungarian secondary school students’ digital and AI literacy with a focus on language learning","year":2025,"lang":"en","type":"article","venue":"GiLE Journal of Skills Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Digital literacy; Lifelong learning; Literacy; Information literacy; Computer literacy; Digital learning; Focus group","score_opus":0.0015844243077330913,"score_gpt":0.2623075271765592,"score_spread":0.2607231028688261,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7087114786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98611337,0.0009996282,0.011806766,0.00010313113,0.00008332754,0.00006745472,0.0000015740017,0.0000045398347,0.00082019647],"genre_scores_gemma":[0.99534893,0.00007507274,0.0025364633,0.00018657856,0.00006826327,0.0000026881419,0.000006630018,0.000010171577,0.0017651808],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99935025,0.000012236726,0.00022847061,0.00012735055,0.0001446364,0.00013702888],"domain_scores_gemma":[0.9996784,0.000011664124,0.0000756619,0.00007602397,0.00007754527,0.0000807236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013442633,0.00011255975,0.0001288793,0.000113311726,0.000061871,0.00012028267,0.00011051966,0.000045757624,0.000010992379],"category_scores_gemma":[0.00005755585,0.00009183714,0.000030448806,0.000069821726,0.000013986779,0.000010920468,0.000084961306,0.00020457477,0.0000020539878],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032602172,0.00041814498,0.2500381,0.0002046152,0.0012011513,0.00022547945,0.006091375,0.0014423968,0.13269472,0.00002060084,0.0021851314,0.6051523],"study_design_scores_gemma":[0.00400474,0.0011721797,0.47277278,0.0015638176,0.000039149898,0.00034206558,0.002166657,0.000023298137,0.3422515,0.000046034278,0.17497312,0.00064464146],"about_ca_topic_score_codex":6.241073e-7,"about_ca_topic_score_gemma":0.0000010193058,"teacher_disagreement_score":0.6045076,"about_ca_system_score_codex":0.00002640954,"about_ca_system_score_gemma":0.00014117481,"threshold_uncertainty_score":0.37450096},"labels":[],"label_agreement":null},{"id":"W7087205972","doi":"","title":"Collaborative multicenter trials in Latin America: challenges and opportunities in orthopedic and trauma surgery","year":2013,"lang":"en","type":"article","venue":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Orthopedic surgery; Context (archaeology); Latin Americans; Exploratory research; Plan (archaeology); Action plan; Promotion (chess); Orthopedic Procedures","score_opus":0.039783421312152706,"score_gpt":0.28176244423833813,"score_spread":0.24197902292618542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7087205972","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979443,0.009001885,0.00031263314,0.00605129,0.00016369122,0.00047984236,0.000018969868,0.000027061156,0.0045016236],"genre_scores_gemma":[0.9886767,0.009875222,0.00085319026,0.00010488077,0.00013990996,0.00021363162,0.00006097256,0.000021056525,0.000054416258],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981897,0.00038961146,0.00054510974,0.0004033483,0.00015852661,0.00031371653],"domain_scores_gemma":[0.99912775,0.0002511251,0.00014767374,0.00018256053,0.0001144259,0.00017647522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007084102,0.00022588424,0.00044374613,0.0002658051,0.00007035333,0.00006418169,0.00009135572,0.00022571985,0.000008545209],"category_scores_gemma":[0.00067435,0.00021343012,0.000062253355,0.00013775878,0.000024660381,0.000030760526,0.000097628814,0.00017245664,7.5548706e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015186204,0.0020515407,0.037628822,0.0012416928,0.00074371905,0.00057071744,0.022169223,0.00062316516,0.16187753,0.16445237,0.0024465914,0.604676],"study_design_scores_gemma":[0.002417347,0.0001499636,0.25123397,0.00024170145,0.0000380394,0.00019935578,0.0052897767,0.0007216444,0.0053201895,0.00011441812,0.73355484,0.0007187668],"about_ca_topic_score_codex":0.00000281283,"about_ca_topic_score_gemma":0.00030815942,"teacher_disagreement_score":0.73110825,"about_ca_system_score_codex":0.000042410094,"about_ca_system_score_gemma":0.00011943511,"threshold_uncertainty_score":0.8703428},"labels":[],"label_agreement":null},{"id":"W7087259626","doi":"10.5281/zenodo.17314428","title":"Displacement Data for \"The East Zambales Fault: Kinematic Congruence with Plate Motion and Development of Volcano-Tectonic Elements in Central Luzon, Philippines\"","year":2025,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nuclear Safety Commission","funders":"","keywords":"Kinematics; Displacement (psychology); Congruence (geometry); Motion (physics); Development (topology)","score_opus":0.022127611391742682,"score_gpt":0.28323575954617863,"score_spread":0.26110814815443595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7087259626","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0068852073,0.001278422,0.07839187,0.00022193715,0.0001786832,0.002363381,0.91051435,0.000044858094,0.00012127525],"genre_scores_gemma":[0.017269943,0.00042373646,0.00081206945,0.00002223415,0.00004795988,6.0891387e-7,0.9811945,0.00014480464,0.00008415559],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988271,0.000052760737,0.00030403744,0.0003942313,0.00017555464,0.00024634105],"domain_scores_gemma":[0.9990622,0.0000109929115,0.00011892136,0.00060491904,0.00015006185,0.000052926738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035731244,0.0001598467,0.00015189528,0.00008921857,0.00032246567,0.0000938814,0.00077902793,0.00006825433,0.00015798507],"category_scores_gemma":[0.00021944504,0.00013431067,0.000015573152,0.00013181198,0.00008493481,0.00000784691,0.0010652652,0.000111952904,0.0000058226174],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025595343,0.00016691208,0.000012506574,0.0015850757,0.00030016006,0.0000027923695,0.00022654471,0.0012327438,0.00920674,0.000012970285,0.9534907,0.03350695],"study_design_scores_gemma":[0.0007280913,0.00013512323,0.00032807453,0.00014711595,0.000040002953,0.000010595149,0.00013605779,0.0009565518,0.0011461321,9.3819705e-7,0.9962203,0.0001509986],"about_ca_topic_score_codex":0.000015518677,"about_ca_topic_score_gemma":0.00003478223,"teacher_disagreement_score":0.077579804,"about_ca_system_score_codex":0.00004282634,"about_ca_system_score_gemma":0.00001901244,"threshold_uncertainty_score":0.547703},"labels":[],"label_agreement":null},{"id":"W7095617710","doi":"","title":"Simon Gravel Genome Quebec Innovation Centre","year":2014,"lang":"en","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"","score_opus":0.004729305771273956,"score_gpt":0.25055424558893963,"score_spread":0.24582493981766568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7095617710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7881729,0.00007272257,0.20368673,0.00018559369,0.000099714045,0.00006335651,0.0000019363927,0.000020388421,0.007696631],"genre_scores_gemma":[0.99209094,0.000009106003,0.001210519,0.00025515983,0.00019930134,0.0000019200702,0.000112733374,0.0000105456475,0.0061098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995794,0.000008127675,0.000100967685,0.00014404095,0.00004778208,0.00011963007],"domain_scores_gemma":[0.9997428,0.0000024547744,0.000017092512,0.00016579698,0.000046889007,0.000024942128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006864657,0.0000705685,0.00005025987,0.000030858642,0.00002202135,0.000011756028,0.00006352964,0.00005994113,0.000041642048],"category_scores_gemma":[0.000030421596,0.00006638277,0.00002148123,0.000083179606,0.000010704671,8.107356e-7,0.000032924396,0.000028192026,0.000021293541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004701331,0.000010780826,0.0008443731,0.000007677363,0.000009526241,1.5313684e-7,0.00001714035,0.00056157843,0.9894379,0.0020693617,0.0011449882,0.0058918507],"study_design_scores_gemma":[0.00033959447,0.00006504226,0.015737923,0.0000032188889,0.0000064751916,0.0000015624466,0.000065440465,0.00087699655,0.68974423,0.00013254973,0.29280505,0.00022190121],"about_ca_topic_score_codex":0.000104438666,"about_ca_topic_score_gemma":0.0006399965,"teacher_disagreement_score":0.2996936,"about_ca_system_score_codex":0.0000050135627,"about_ca_system_score_gemma":0.0000111854015,"threshold_uncertainty_score":0.27070108},"labels":[],"label_agreement":null},{"id":"W7102397162","doi":"10.6084/m9.figshare.30474248","title":"Additional file of Spatiotemporal control of genome engineering in cone photoreceptors","year":2025,"lang":"","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Genome engineering; Cone (formal languages); Genome; Control (management)","score_opus":0.005069937459426682,"score_gpt":0.23188593043269845,"score_spread":0.22681599297327176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7102397162","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005419379,0.0012545899,0.00007825955,0.0000074324726,0.00004575752,0.0002410117,0.9969011,0.0000046723612,0.00092525774],"genre_scores_gemma":[0.4325972,0.000007459286,0.00016867297,0.000015484173,0.000057618527,0.00020217813,0.56669563,0.000012111195,0.00024363675],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989439,0.000017834462,0.00045107838,0.00025728458,0.00010983531,0.00022006786],"domain_scores_gemma":[0.9991928,0.00023508859,0.00014252985,0.00023207495,0.0001463311,0.0000511808],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002590073,0.00019297692,0.0003099912,0.00014632473,0.000013255026,0.0000066174775,0.00018529018,0.00023326238,0.934748],"category_scores_gemma":[0.0015350248,0.00023897432,0.00014593742,0.00022227643,0.00001489368,0.0000034527643,0.000092510294,0.00012311539,0.000036049783],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040239796,0.000069727415,0.000020768204,0.00075301185,0.0001099022,0.0000021332723,0.000020475332,0.006637808,0.023844505,0.0000017614955,0.96777445,0.00072520366],"study_design_scores_gemma":[0.00097141904,0.00015478923,0.005320096,0.003493376,0.000013668723,0.0000014642432,0.000022154152,0.0057292418,0.07624319,0.000001565106,0.9077989,0.00025015202],"about_ca_topic_score_codex":0.0000056121244,"about_ca_topic_score_gemma":0.00000952934,"teacher_disagreement_score":0.93471193,"about_ca_system_score_codex":0.000024618943,"about_ca_system_score_gemma":0.00024052773,"threshold_uncertainty_score":0.974509},"labels":[],"label_agreement":null},{"id":"W7102405367","doi":"10.6084/m9.figshare.30474248.v1","title":"Additional file of Spatiotemporal control of genome engineering in cone photoreceptors","year":2025,"lang":"","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Genome engineering; Cone (formal languages); Genome; Control (management)","score_opus":0.005069937459426682,"score_gpt":0.23188593043269845,"score_spread":0.22681599297327176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7102405367","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005419379,0.0012545899,0.00007825955,0.0000074324726,0.00004575752,0.0002410117,0.9969011,0.0000046723612,0.00092525774],"genre_scores_gemma":[0.4325972,0.000007459286,0.00016867297,0.000015484173,0.000057618527,0.00020217813,0.56669563,0.000012111195,0.00024363675],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989439,0.000017834462,0.00045107838,0.00025728458,0.00010983531,0.00022006786],"domain_scores_gemma":[0.9991928,0.00023508859,0.00014252985,0.00023207495,0.0001463311,0.0000511808],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002590073,0.00019297692,0.0003099912,0.00014632473,0.000013255026,0.0000066174775,0.00018529018,0.00023326238,0.934748],"category_scores_gemma":[0.0015350248,0.00023897432,0.00014593742,0.00022227643,0.00001489368,0.0000034527643,0.000092510294,0.00012311539,0.000036049783],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040239796,0.000069727415,0.000020768204,0.00075301185,0.0001099022,0.0000021332723,0.000020475332,0.006637808,0.023844505,0.0000017614955,0.96777445,0.00072520366],"study_design_scores_gemma":[0.00097141904,0.00015478923,0.005320096,0.003493376,0.000013668723,0.0000014642432,0.000022154152,0.0057292418,0.07624319,0.000001565106,0.9077989,0.00025015202],"about_ca_topic_score_codex":0.0000056121244,"about_ca_topic_score_gemma":0.00000952934,"teacher_disagreement_score":0.93471193,"about_ca_system_score_codex":0.000024618943,"about_ca_system_score_gemma":0.00024052773,"threshold_uncertainty_score":0.974509},"labels":[],"label_agreement":null},{"id":"W7104249602","doi":"10.5281/zenodo.17538615","title":"Universal Mutation-Control Axis (UMX): Toward a Unified Theory of Viral Mutation, Replication Fidelity, and CRISPR–T-Cell Hybrid Defense Systems","year":2025,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Polymerase; Viral replication; Replication (statistics); Nuclease; Signalling; DNA; RNA; DNA replication; Computational model","score_opus":0.010625568585999917,"score_gpt":0.25249226397429814,"score_spread":0.24186669538829822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7104249602","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42013723,0.0011126912,0.5612929,0.00027527593,0.00011740268,0.0006766335,0.00023901266,0.00015071679,0.015998172],"genre_scores_gemma":[0.9982454,0.00008681778,0.00016129747,0.00004903165,0.00003688007,1.3174088e-7,0.00073471904,0.00015599673,0.00052971655],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990022,0.0001933344,0.00022107897,0.0003232014,0.000113896356,0.00014624672],"domain_scores_gemma":[0.9990517,0.00001949067,0.00007841235,0.00037234338,0.00041885482,0.000059199258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048731326,0.00009755862,0.000107320644,0.00012059328,0.00030114083,0.000108713226,0.00025236554,0.000052831634,0.00008802582],"category_scores_gemma":[0.0003756927,0.00010923009,0.000035100555,0.00015650604,0.00008786009,0.000011691015,0.00021980364,0.000076821605,0.000032211257],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081229355,0.00025540887,0.000060300834,0.0007901826,0.0003109577,0.00002220838,0.0015323157,0.010361541,0.8645622,0.0231615,0.03823898,0.059892118],"study_design_scores_gemma":[0.006198165,0.0013517158,0.004846708,0.00014429651,0.00025141746,0.00031158215,0.0043351273,0.01666797,0.39685425,0.002124176,0.5660992,0.00081538357],"about_ca_topic_score_codex":0.000020674892,"about_ca_topic_score_gemma":2.389209e-7,"teacher_disagreement_score":0.5781082,"about_ca_system_score_codex":0.000028578557,"about_ca_system_score_gemma":0.000008925878,"threshold_uncertainty_score":0.4454274},"labels":[],"label_agreement":null},{"id":"W7104274830","doi":"10.5281/zenodo.17538614","title":"Universal Mutation-Control Axis (UMX): Toward a Unified Theory of Viral Mutation, Replication Fidelity, and CRISPR–T-Cell Hybrid Defense Systems","year":2025,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Polymerase; Viral replication; Replication (statistics); Nuclease; Signalling; DNA; RNA; DNA replication; Computational model","score_opus":0.010625568585999917,"score_gpt":0.25249226397429814,"score_spread":0.24186669538829822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7104274830","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42013723,0.0011126912,0.5612929,0.00027527593,0.00011740268,0.0006766335,0.00023901266,0.00015071679,0.015998172],"genre_scores_gemma":[0.9982454,0.00008681778,0.00016129747,0.00004903165,0.00003688007,1.3174088e-7,0.00073471904,0.00015599673,0.00052971655],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990022,0.0001933344,0.00022107897,0.0003232014,0.000113896356,0.00014624672],"domain_scores_gemma":[0.9990517,0.00001949067,0.00007841235,0.00037234338,0.00041885482,0.000059199258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048731326,0.00009755862,0.000107320644,0.00012059328,0.00030114083,0.000108713226,0.00025236554,0.000052831634,0.00008802582],"category_scores_gemma":[0.0003756927,0.00010923009,0.000035100555,0.00015650604,0.00008786009,0.000011691015,0.00021980364,0.000076821605,0.000032211257],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081229355,0.00025540887,0.000060300834,0.0007901826,0.0003109577,0.00002220838,0.0015323157,0.010361541,0.8645622,0.0231615,0.03823898,0.059892118],"study_design_scores_gemma":[0.006198165,0.0013517158,0.004846708,0.00014429651,0.00025141746,0.00031158215,0.0043351273,0.01666797,0.39685425,0.002124176,0.5660992,0.00081538357],"about_ca_topic_score_codex":0.000020674892,"about_ca_topic_score_gemma":2.389209e-7,"teacher_disagreement_score":0.5781082,"about_ca_system_score_codex":0.000028578557,"about_ca_system_score_gemma":0.000008925878,"threshold_uncertainty_score":0.4454274},"labels":[],"label_agreement":null},{"id":"W7104581088","doi":"10.1525/elementa.2024.00080","title":"Engaging publics on gene editing of farm animals: Evidence from the online gray literature","year":2025,"lang":"en","type":"article","venue":"Elementa Science of the Anthropocene","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Publics; Gray (unit); Public engagement; License; Grey literature; Profiling (computer programming); Online discussion; Social media","score_opus":0.014468689808256862,"score_gpt":0.34751871485862307,"score_spread":0.3330500250503662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7104581088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912134,0.004453406,0.0014454232,0.0019628804,0.00054371404,0.00013887366,0.00007727747,0.0000048553065,0.00016019482],"genre_scores_gemma":[0.9971956,0.000633984,0.0016922058,0.00024364324,0.00018262885,0.0000027468207,0.00001327333,0.000005803827,0.00003011062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989377,0.00004287338,0.00023496004,0.00028359165,0.00029018405,0.00021064775],"domain_scores_gemma":[0.9990927,0.00005105753,0.000116871095,0.0005643807,0.00014806037,0.000026929254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060005375,0.00011214299,0.0001107085,0.00004546624,0.00024471915,0.000042017055,0.0009045018,0.0000376246,0.000012217384],"category_scores_gemma":[0.00051841355,0.00006800078,0.000072593946,0.0005838703,0.00049211615,0.000008280724,0.00040794455,0.000121477504,2.156857e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012668609,0.000037893173,0.008258752,0.000014319614,0.00001883418,2.0096117e-7,0.00012697108,0.0003905187,0.98616296,0.00012698995,0.00048700374,0.004362911],"study_design_scores_gemma":[0.00014555955,0.00008082135,0.018454302,0.00030012324,0.000016149608,9.119948e-7,0.0004987762,0.0003872125,0.9793379,0.000100910365,0.00061190344,0.00006543968],"about_ca_topic_score_codex":0.00007370876,"about_ca_topic_score_gemma":0.00003731556,"teacher_disagreement_score":0.0101955505,"about_ca_system_score_codex":0.000017425366,"about_ca_system_score_gemma":0.00010723136,"threshold_uncertainty_score":0.27729914},"labels":[],"label_agreement":null},{"id":"W7105514874","doi":"10.6084/m9.figshare.30595892","title":"Additional file 2 of Discarded diversity: novel megaphages, auxiliary metabolic genes, and virally encoded CRISPR-Cas systems in landfills","year":2025,"lang":"","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Production (economics); Key (lock); Work (physics); Automation","score_opus":0.010547463552549386,"score_gpt":0.25518805077048073,"score_spread":0.24464058721793136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7105514874","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00046634162,0.025849244,0.00006425757,0.000022683322,0.000111971225,0.0003606538,0.97169465,0.0000101300275,0.0014200716],"genre_scores_gemma":[0.15486535,0.00036328807,0.00026930284,0.000066276596,0.0001600502,0.00034516325,0.8422136,0.000023473782,0.0016935416],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984469,0.00005256011,0.00040973988,0.0005426474,0.00019931619,0.0003488591],"domain_scores_gemma":[0.99901307,0.00022786125,0.0001362283,0.00036578978,0.00014827872,0.00010879719],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000513409,0.00031687994,0.00044477565,0.00017591297,0.00011915109,0.000045749443,0.00030271366,0.00033910494,0.47300372],"category_scores_gemma":[0.0007688765,0.00034802043,0.00015623574,0.00026854992,0.000029307379,0.000011434991,0.0010084452,0.000173469,0.0000338267],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003504836,0.00009336272,0.00006549392,0.0007329685,0.00020698037,0.000012423108,0.00005486564,0.00053267967,0.0068625226,0.0000075892785,0.98905593,0.0023401221],"study_design_scores_gemma":[0.0009310394,0.000066552595,0.009401832,0.0028249905,0.000071292685,0.000015544256,0.00014772492,0.0022860894,0.019823363,0.0000054997963,0.96402055,0.00040550707],"about_ca_topic_score_codex":0.00006849419,"about_ca_topic_score_gemma":0.00009156826,"teacher_disagreement_score":0.4729699,"about_ca_system_score_codex":0.00002382072,"about_ca_system_score_gemma":0.00022900694,"threshold_uncertainty_score":0.9998972},"labels":[],"label_agreement":null},{"id":"W7105542270","doi":"10.6084/m9.figshare.30595892.v1","title":"Additional file 2 of Discarded diversity: novel megaphages, auxiliary metabolic genes, and virally encoded CRISPR-Cas systems in landfills","year":2025,"lang":"","type":"article","venue":"Figshare","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Production (economics); Key (lock); Work (physics); Automation","score_opus":0.010547463552549386,"score_gpt":0.25518805077048073,"score_spread":0.24464058721793136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7105542270","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00046634162,0.025849244,0.00006425757,0.000022683322,0.000111971225,0.0003606538,0.97169465,0.0000101300275,0.0014200716],"genre_scores_gemma":[0.15486535,0.00036328807,0.00026930284,0.000066276596,0.0001600502,0.00034516325,0.8422136,0.000023473782,0.0016935416],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984469,0.00005256011,0.00040973988,0.0005426474,0.00019931619,0.0003488591],"domain_scores_gemma":[0.99901307,0.00022786125,0.0001362283,0.00036578978,0.00014827872,0.00010879719],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000513409,0.00031687994,0.00044477565,0.00017591297,0.00011915109,0.000045749443,0.00030271366,0.00033910494,0.47300372],"category_scores_gemma":[0.0007688765,0.00034802043,0.00015623574,0.00026854992,0.000029307379,0.000011434991,0.0010084452,0.000173469,0.0000338267],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003504836,0.00009336272,0.00006549392,0.0007329685,0.00020698037,0.000012423108,0.00005486564,0.00053267967,0.0068625226,0.0000075892785,0.98905593,0.0023401221],"study_design_scores_gemma":[0.0009310394,0.000066552595,0.009401832,0.0028249905,0.000071292685,0.000015544256,0.00014772492,0.0022860894,0.019823363,0.0000054997963,0.96402055,0.00040550707],"about_ca_topic_score_codex":0.00006849419,"about_ca_topic_score_gemma":0.00009156826,"teacher_disagreement_score":0.4729699,"about_ca_system_score_codex":0.00002382072,"about_ca_system_score_gemma":0.00022900694,"threshold_uncertainty_score":0.9998972},"labels":[],"label_agreement":null},{"id":"W7106491637","doi":"10.5281/zenodo.17704991","title":"Conscience November 2025 Policy Brief - FDA Announces Plan to Alter Regulatory Regime for n-of-1 Gene Editing","year":2025,"lang":"","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Bespoke; Plan (archaeology); Conscience; Government regulation; Genome editing; Regulatory reform","score_opus":0.017749847964563154,"score_gpt":0.2951845464370402,"score_spread":0.27743469847247704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7106491637","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26217094,0.007968559,0.40714705,0.010985235,0.003341231,0.0058774506,0.006024994,0.0005623346,0.29592222],"genre_scores_gemma":[0.983964,0.00034966774,0.0025192283,0.00063029345,0.0010997411,4.333162e-7,0.0014581927,0.0007362572,0.009242141],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978386,0.0001225891,0.00045265138,0.0007281371,0.00027893498,0.000579054],"domain_scores_gemma":[0.9981447,0.000028348022,0.00013830574,0.0006825642,0.00078549556,0.0002205787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076270435,0.00024058454,0.00025883672,0.00032145585,0.0011056877,0.00034117163,0.0008871218,0.00015538078,0.00043640286],"category_scores_gemma":[0.0012404856,0.00028175715,0.00011601609,0.0007587501,0.00029364025,0.000020400066,0.001086828,0.00015698484,0.00012720763],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017879142,0.000110256966,0.000013738023,0.0004193065,0.00014126001,0.0000020136179,0.0005579902,0.00085697416,0.7072778,0.0030578782,0.2432076,0.044176403],"study_design_scores_gemma":[0.0004590844,0.00033998422,0.00020810979,0.00012075231,0.000027017393,0.000015324236,0.0002389593,0.0003339269,0.21081652,0.000048140482,0.78717726,0.00021490363],"about_ca_topic_score_codex":0.000023531742,"about_ca_topic_score_gemma":8.0928316e-7,"teacher_disagreement_score":0.7217931,"about_ca_system_score_codex":0.00009229068,"about_ca_system_score_gemma":0.000053307667,"threshold_uncertainty_score":0.99996346},"labels":[],"label_agreement":null},{"id":"W7106523902","doi":"10.5281/zenodo.17704990","title":"Conscience November 2025 Policy Brief - FDA Announces Plan to Alter Regulatory Regime for n-of-1 Gene Editing","year":2025,"lang":"","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Bespoke; Plan (archaeology); Conscience; Government regulation; Genome editing; Regulatory reform","score_opus":0.017749847964563154,"score_gpt":0.2951845464370402,"score_spread":0.27743469847247704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7106523902","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.26217094,0.007968559,0.40714705,0.010985235,0.003341231,0.0058774506,0.006024994,0.0005623346,0.29592222],"genre_scores_gemma":[0.983964,0.00034966774,0.0025192283,0.00063029345,0.0010997411,4.333162e-7,0.0014581927,0.0007362572,0.009242141],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978386,0.0001225891,0.00045265138,0.0007281371,0.00027893498,0.000579054],"domain_scores_gemma":[0.9981447,0.000028348022,0.00013830574,0.0006825642,0.00078549556,0.0002205787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076270435,0.00024058454,0.00025883672,0.00032145585,0.0011056877,0.00034117163,0.0008871218,0.00015538078,0.00043640286],"category_scores_gemma":[0.0012404856,0.00028175715,0.00011601609,0.0007587501,0.00029364025,0.000020400066,0.001086828,0.00015698484,0.00012720763],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017879142,0.000110256966,0.000013738023,0.0004193065,0.00014126001,0.0000020136179,0.0005579902,0.00085697416,0.7072778,0.0030578782,0.2432076,0.044176403],"study_design_scores_gemma":[0.0004590844,0.00033998422,0.00020810979,0.00012075231,0.000027017393,0.000015324236,0.0002389593,0.0003339269,0.21081652,0.000048140482,0.78717726,0.00021490363],"about_ca_topic_score_codex":0.000023531742,"about_ca_topic_score_gemma":8.0928316e-7,"teacher_disagreement_score":0.7217931,"about_ca_system_score_codex":0.00009229068,"about_ca_system_score_gemma":0.000053307667,"threshold_uncertainty_score":0.99996346},"labels":[],"label_agreement":null},{"id":"W7106819679","doi":"10.5281/zenodo.17721958","title":"CRISPR Genome Editing Accuracy: Framework 50 Achieves 80% Confidence Through Convergent Validation with CASGEVY Clinical Trial Correlation (93% Success Rate)","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"CRISPR; Probabilistic logic; Genome editing; Correlation; Concordance; Clinical trial; Fidelity; Redundancy (engineering)","score_opus":0.04837693192046138,"score_gpt":0.3619568168930636,"score_spread":0.3135798849726022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7106819679","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10358363,0.0011191384,0.8792605,0.00080048636,0.0029255517,0.0029629213,0.00077500613,0.0003275436,0.008245256],"genre_scores_gemma":[0.9735065,0.004640718,0.0033751247,0.00025030755,0.002946911,0.0000015058555,0.012787237,0.0012979207,0.0011937873],"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","domain_scores_codex":[0.99372715,0.0015238461,0.0014804633,0.0018207163,0.0006536379,0.0007942098],"domain_scores_gemma":[0.9954932,0.00022918101,0.00086688367,0.00148185,0.0015939785,0.00033496023],"candidate_categories":["metaepi_narrow","sts","scholarly_communication","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0024439304,0.0006730135,0.0006801989,0.00020640757,0.0021244704,0.0013950022,0.0018481923,0.0009232141,0.0039983983],"category_scores_gemma":[0.0046175397,0.0007319268,0.00029355352,0.00053189095,0.00045277536,0.00007232894,0.0034379119,0.0016855551,0.00078666024],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.11023666,0.0067233704,0.0009589114,0.009185752,0.009378189,0.00026119885,0.01661291,0.3572896,0.14394055,0.023869874,0.1274082,0.19413477],"study_design_scores_gemma":[0.010411575,0.0023879677,0.0014413701,0.00074299506,0.00042216067,0.0000900358,0.00084146747,0.0031060018,0.012783923,0.00036578678,0.9661302,0.001276507],"about_ca_topic_score_codex":0.00006082363,"about_ca_topic_score_gemma":0.000001674372,"teacher_disagreement_score":0.87588537,"about_ca_system_score_codex":0.00018443429,"about_ca_system_score_gemma":0.00009291962,"threshold_uncertainty_score":0.99999136},"labels":[],"label_agreement":null},{"id":"W7106824095","doi":"10.5281/zenodo.17721959","title":"CRISPR Accuracy Engineering via Framework 50 Computational Redundancy: Achieving High-Confidence Editing Fidelity Through Convergent Validation","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"CRISPR; Redundancy (engineering); Computational model; Computational complexity theory; Fidelity; Source code; In silico; Key (lock)","score_opus":0.0198054363562525,"score_gpt":0.30219675403809837,"score_spread":0.2823913176818459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7106824095","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018271036,0.0012520818,0.97370726,0.0008101724,0.0016775448,0.0009978634,0.0007262914,0.0003828821,0.0021748787],"genre_scores_gemma":[0.96075994,0.0014154263,0.023621893,0.00019799075,0.001505415,7.4904744e-7,0.01113579,0.0011412821,0.00022148853],"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954465,0.000433079,0.0010810037,0.0015331396,0.00069155043,0.00081473344],"domain_scores_gemma":[0.99654543,0.00014012624,0.00047731906,0.0011669265,0.0013940654,0.00027614174],"candidate_categories":["metaepi_narrow","sts","scholarly_communication","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011230652,0.0006418234,0.00051005627,0.00024523347,0.0020718363,0.0011481959,0.0017179131,0.00060489605,0.0029721833],"category_scores_gemma":[0.003632385,0.0008401676,0.00026042777,0.0005136182,0.00017982385,0.000065145425,0.004600791,0.0013153884,0.0004949455],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023452107,0.0003751929,0.000020566096,0.0026612196,0.0008953792,0.00001979763,0.0027150472,0.7984957,0.09849195,0.008128938,0.027329005,0.060632676],"study_design_scores_gemma":[0.0010461123,0.00039269644,0.0012675585,0.0016569094,0.00023998045,0.0001386244,0.00044973014,0.04506557,0.06248419,0.0027495788,0.8829326,0.0015764231],"about_ca_topic_score_codex":0.000077780045,"about_ca_topic_score_gemma":3.4228026e-7,"teacher_disagreement_score":0.95008534,"about_ca_system_score_codex":0.00029801295,"about_ca_system_score_gemma":0.000047968126,"threshold_uncertainty_score":0.9998887},"labels":[],"label_agreement":null},{"id":"W7108073414","doi":"10.5281/zenodo.17770862","title":"CRISPR-Accuracy Framework 50: Convergent Off-Target Suppression and On-Target Enhancement for 99.9% Genomic Precision","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"In silico; Redundancy (engineering); Computational model; CRISPR; Data validation; Biological data; Cross-validation","score_opus":0.018429710070654665,"score_gpt":0.30346259520471547,"score_spread":0.2850328851340608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7108073414","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.041535042,0.008855396,0.9252159,0.001073761,0.002147694,0.0043887133,0.0031232266,0.00026146253,0.013398782],"genre_scores_gemma":[0.9192584,0.024602003,0.029207977,0.0006250133,0.0014967015,0.000004405048,0.018400338,0.0028879798,0.0035171853],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.995622,0.00049552403,0.0008454075,0.0017424284,0.00046403395,0.00083064276],"domain_scores_gemma":[0.9969958,0.00011646856,0.00034411452,0.0014097812,0.000721408,0.00041242817],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011700364,0.0006630243,0.0005301168,0.00029107844,0.0019537974,0.00074328453,0.0013776212,0.00056837936,0.0046695606],"category_scores_gemma":[0.0017115783,0.0007384711,0.0002678842,0.00020204972,0.00018524223,0.000019324087,0.0053390344,0.0007715329,0.00045598866],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002421312,0.0009808935,0.000016854336,0.0024672996,0.0008755892,0.000009985248,0.0021745989,0.011836511,0.47860536,0.0010677788,0.23441984,0.265124],"study_design_scores_gemma":[0.0010009194,0.0010099004,0.00022581434,0.0005258162,0.00007620547,0.000017008248,0.00017597733,0.0029812895,0.12794784,0.0005205251,0.86488515,0.00063355325],"about_ca_topic_score_codex":0.000006401007,"about_ca_topic_score_gemma":1.5127691e-7,"teacher_disagreement_score":0.89600796,"about_ca_system_score_codex":0.00019913414,"about_ca_system_score_gemma":0.000033622422,"threshold_uncertainty_score":0.99950665},"labels":[],"label_agreement":null},{"id":"W7108080666","doi":"10.5281/zenodo.17772221","title":"CRISPR-Accuracy - Convergent Off-Target Suppression and On-Target Enhancement for 99.9% Genomic Precision","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"Redundancy (engineering); CRISPR; R package; Key (lock); Fidelity; Computational model","score_opus":0.019013656293165072,"score_gpt":0.29834237579067335,"score_spread":0.27932871949750826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7108080666","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13965462,0.016274165,0.7868507,0.0021099115,0.0041229213,0.010262299,0.007849682,0.0005120508,0.032363668],"genre_scores_gemma":[0.9358388,0.022394922,0.008826089,0.00047483912,0.001061129,0.0000043235996,0.022730486,0.0025284837,0.0061409282],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99601895,0.00035086682,0.00078516355,0.0016491286,0.00042492195,0.0007709972],"domain_scores_gemma":[0.99722934,0.0000735964,0.0003082334,0.0012363154,0.0007757925,0.00037672624],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009395942,0.00061333604,0.0005014361,0.0002903134,0.0018427562,0.0006567741,0.0012218141,0.00045619544,0.0042618713],"category_scores_gemma":[0.0011272922,0.00068011455,0.0002403607,0.00018846593,0.00017177447,0.000019010373,0.0049847607,0.0005401766,0.0003616916],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018219234,0.0006858094,0.000008679858,0.001773588,0.00057550607,0.000007503668,0.0011369408,0.007973009,0.51382023,0.00044327785,0.2730602,0.19869335],"study_design_scores_gemma":[0.0012169905,0.0010090637,0.00013949687,0.00026927178,0.00006523489,0.000017153137,0.00013107329,0.0052477294,0.20214786,0.00016119568,0.7890667,0.000528268],"about_ca_topic_score_codex":0.0000072497346,"about_ca_topic_score_gemma":2.0825799e-7,"teacher_disagreement_score":0.7961842,"about_ca_system_score_codex":0.00019085292,"about_ca_system_score_gemma":0.00003591607,"threshold_uncertainty_score":0.999565},"labels":[],"label_agreement":null},{"id":"W7108479836","doi":"10.5281/zenodo.17796387","title":"CRISPR-Accuracy - Convergent Off-Target Suppression and On-Target Enhancement for 99.9% Genomic Precision","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"Redundancy (engineering); CRISPR; R package; Key (lock); Fidelity; Computational model","score_opus":0.019013656293165072,"score_gpt":0.29834237579067335,"score_spread":0.27932871949750826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7108479836","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13965462,0.016274165,0.7868507,0.0021099115,0.0041229213,0.010262299,0.007849682,0.0005120508,0.032363668],"genre_scores_gemma":[0.9358388,0.022394922,0.008826089,0.00047483912,0.001061129,0.0000043235996,0.022730486,0.0025284837,0.0061409282],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99601895,0.00035086682,0.00078516355,0.0016491286,0.00042492195,0.0007709972],"domain_scores_gemma":[0.99722934,0.0000735964,0.0003082334,0.0012363154,0.0007757925,0.00037672624],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009395942,0.00061333604,0.0005014361,0.0002903134,0.0018427562,0.0006567741,0.0012218141,0.00045619544,0.0042618713],"category_scores_gemma":[0.0011272922,0.00068011455,0.0002403607,0.00018846593,0.00017177447,0.000019010373,0.0049847607,0.0005401766,0.0003616916],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018219234,0.0006858094,0.000008679858,0.001773588,0.00057550607,0.000007503668,0.0011369408,0.007973009,0.51382023,0.00044327785,0.2730602,0.19869335],"study_design_scores_gemma":[0.0012169905,0.0010090637,0.00013949687,0.00026927178,0.00006523489,0.000017153137,0.00013107329,0.0052477294,0.20214786,0.00016119568,0.7890667,0.000528268],"about_ca_topic_score_codex":0.0000072497346,"about_ca_topic_score_gemma":2.0825799e-7,"teacher_disagreement_score":0.7961842,"about_ca_system_score_codex":0.00019085292,"about_ca_system_score_gemma":0.00003591607,"threshold_uncertainty_score":0.999565},"labels":[],"label_agreement":null},{"id":"W7108490585","doi":"10.5281/zenodo.17797646","title":"CRISPR-Accuracy - Convergent Off-Target Suppression and On-Target Enhancement for 99.9% Genomic Precision","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"Redundancy (engineering); CRISPR; R package; Key (lock); Fidelity; Computational model","score_opus":0.019013656293165072,"score_gpt":0.29834237579067335,"score_spread":0.27932871949750826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7108490585","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13965462,0.016274165,0.7868507,0.0021099115,0.0041229213,0.010262299,0.007849682,0.0005120508,0.032363668],"genre_scores_gemma":[0.9358388,0.022394922,0.008826089,0.00047483912,0.001061129,0.0000043235996,0.022730486,0.0025284837,0.0061409282],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99601895,0.00035086682,0.00078516355,0.0016491286,0.00042492195,0.0007709972],"domain_scores_gemma":[0.99722934,0.0000735964,0.0003082334,0.0012363154,0.0007757925,0.00037672624],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009395942,0.00061333604,0.0005014361,0.0002903134,0.0018427562,0.0006567741,0.0012218141,0.00045619544,0.0042618713],"category_scores_gemma":[0.0011272922,0.00068011455,0.0002403607,0.00018846593,0.00017177447,0.000019010373,0.0049847607,0.0005401766,0.0003616916],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018219234,0.0006858094,0.000008679858,0.001773588,0.00057550607,0.000007503668,0.0011369408,0.007973009,0.51382023,0.00044327785,0.2730602,0.19869335],"study_design_scores_gemma":[0.0012169905,0.0010090637,0.00013949687,0.00026927178,0.00006523489,0.000017153137,0.00013107329,0.0052477294,0.20214786,0.00016119568,0.7890667,0.000528268],"about_ca_topic_score_codex":0.0000072497346,"about_ca_topic_score_gemma":2.0825799e-7,"teacher_disagreement_score":0.7961842,"about_ca_system_score_codex":0.00019085292,"about_ca_system_score_gemma":0.00003591607,"threshold_uncertainty_score":0.999565},"labels":[],"label_agreement":null},{"id":"W7108733851","doi":"10.5376/cmb.2025.15.0010","title":"Computational Prediction of Off-Target Effects in CRISPR Systems CRISPR","year":2025,"lang":"","type":"article","venue":"Computational Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CRISPR; Process (computing); Computational model; Field (mathematics); Key (lock); Genome editing","score_opus":0.0042569483841047575,"score_gpt":0.30875250444995767,"score_spread":0.30449555606585293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7108733851","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08873152,0.031491537,0.87603664,0.00023209806,0.0016360454,0.0007885076,0.00023440129,0.000019921981,0.00082930946],"genre_scores_gemma":[0.9877115,0.00013081972,0.010012782,0.00026230834,0.00012932466,0.00008338531,0.0015533126,0.00003741246,0.00007917731],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9968765,0.0004253426,0.0010868175,0.00087015756,0.00023626108,0.00050492695],"domain_scores_gemma":[0.99856806,0.00023573963,0.00024849194,0.00037468213,0.00046061917,0.00011241778],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037738399,0.00045460372,0.00066310196,0.00052723405,0.00008644989,0.00003321224,0.00036612005,0.000612954,0.000011409729],"category_scores_gemma":[0.00027460157,0.000539032,0.00025332143,0.0005484807,0.0002719102,0.000007677195,0.00026271012,0.00028926219,0.0000068014947],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013586186,0.0002884214,0.010079129,0.0006752679,0.00043532482,0.000017513063,0.000055637498,0.8935465,0.055234134,0.035510197,0.0006510985,0.0033708613],"study_design_scores_gemma":[0.00558165,0.0013208477,0.04247586,0.00073666114,0.00023101813,0.000062204796,0.00013597868,0.83282393,0.032201245,0.077230595,0.0063021434,0.0008978689],"about_ca_topic_score_codex":0.000044285458,"about_ca_topic_score_gemma":0.0000035152736,"teacher_disagreement_score":0.89897996,"about_ca_system_score_codex":0.000090469446,"about_ca_system_score_gemma":0.00050437934,"threshold_uncertainty_score":0.99970615},"labels":[],"label_agreement":null},{"id":"W7110306144","doi":"10.64898/2025.12.02.691602","title":"A guide RNA repeat checkpoint steers CRISPR-Cas9 catalysis","year":2025,"lang":"en","type":"article","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; McGill University","funders":"","keywords":"Cas9; RNA; Guide RNA; CRISPR; Mechanism (biology); RNA editing; Gene; Nucleic acid structure","score_opus":0.005145636168257194,"score_gpt":0.2476263566090828,"score_spread":0.2424807204408256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7110306144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94849455,0.0038134244,0.045401942,0.0003934358,0.000756499,0.00037612108,0.00004084257,0.00017699006,0.0005462103],"genre_scores_gemma":[0.9953235,0.0002778147,0.0033721102,0.0003517734,0.00022641606,0.000063524414,7.6485344e-7,0.00005523166,0.00032886196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982804,0.000039390965,0.0003953882,0.0006655449,0.00016936693,0.0004498914],"domain_scores_gemma":[0.9984513,0.000013255851,0.00008370989,0.0010703834,0.00021857781,0.00016275847],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000328435,0.000308664,0.00026463543,0.00015864044,0.00012458402,0.000071002796,0.00034540892,0.00022180779,0.00002368295],"category_scores_gemma":[0.0002435002,0.00033531288,0.00017253785,0.000467102,0.00006896334,0.000008092666,0.00018318684,0.00015131201,0.000029520264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001966233,0.000046535635,0.0014512558,0.00006133352,0.00015830988,0.000013023166,0.0000033348683,0.00014966699,0.9946573,0.000116708354,0.0033079048,0.000014964719],"study_design_scores_gemma":[0.00040931843,0.00004709562,0.009014828,0.000044363962,0.00008054305,2.6900027e-8,0.000007530491,0.00014242632,0.8864644,3.3201977e-7,0.10346131,0.00032782965],"about_ca_topic_score_codex":0.00006092939,"about_ca_topic_score_gemma":0.000008685328,"teacher_disagreement_score":0.108192906,"about_ca_system_score_codex":0.000069917165,"about_ca_system_score_gemma":0.00019690949,"threshold_uncertainty_score":0.9999099},"labels":[],"label_agreement":null},{"id":"W7110777174","doi":"10.5281/zenodo.17861141","title":"CRISPR Genome Editing Accuracy: Framework 50 Achieves 80% Confidence Through Convergent Validation with CASGEVY Clinical Trial Correlation (93% Success Rate)","year":2025,"lang":"","type":"preprint","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Society for the Study of Architecture in Canada","funders":"","keywords":"CRISPR; Probabilistic logic; Genome editing; Correlation; Concordance; Clinical trial; Fidelity; Redundancy (engineering)","score_opus":0.04837693192046138,"score_gpt":0.3619568168930636,"score_spread":0.3135798849726022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7110777174","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10358363,0.0011191384,0.8792605,0.00080048636,0.0029255517,0.0029629213,0.00077500613,0.0003275436,0.008245256],"genre_scores_gemma":[0.9735065,0.004640718,0.0033751247,0.00025030755,0.002946911,0.0000015058555,0.012787237,0.0012979207,0.0011937873],"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","domain_scores_codex":[0.99372715,0.0015238461,0.0014804633,0.0018207163,0.0006536379,0.0007942098],"domain_scores_gemma":[0.9954932,0.00022918101,0.00086688367,0.00148185,0.0015939785,0.00033496023],"candidate_categories":["metaepi_narrow","sts","scholarly_communication","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0024439304,0.0006730135,0.0006801989,0.00020640757,0.0021244704,0.0013950022,0.0018481923,0.0009232141,0.0039983983],"category_scores_gemma":[0.0046175397,0.0007319268,0.00029355352,0.00053189095,0.00045277536,0.00007232894,0.0034379119,0.0016855551,0.00078666024],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.11023666,0.0067233704,0.0009589114,0.009185752,0.009378189,0.00026119885,0.01661291,0.3572896,0.14394055,0.023869874,0.1274082,0.19413477],"study_design_scores_gemma":[0.010411575,0.0023879677,0.0014413701,0.00074299506,0.00042216067,0.0000900358,0.00084146747,0.0031060018,0.012783923,0.00036578678,0.9661302,0.001276507],"about_ca_topic_score_codex":0.00006082363,"about_ca_topic_score_gemma":0.000001674372,"teacher_disagreement_score":0.87588537,"about_ca_system_score_codex":0.00018443429,"about_ca_system_score_gemma":0.00009291962,"threshold_uncertainty_score":0.99999136},"labels":[],"label_agreement":null},{"id":"W7114797554","doi":"10.18609/cgti.2025.137","title":"A decade of innovation: perspectives from the Cell and Gene Therapy Insights Editorial Advisory Board","year":2025,"lang":"en","type":"article","venue":"Cell and Gene Therapy Insights","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services","funders":"","keywords":"Advisory committee; Snapshot (computer storage); Genetic enhancement; Heading (navigation); Cell therapy","score_opus":0.006957399436092769,"score_gpt":0.2524517953633861,"score_spread":0.2454943959272933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7114797554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.887355,0.10911246,0.0010308191,0.000104654704,0.0016399717,0.00021875779,0.000010506838,0.000011050612,0.0005167412],"genre_scores_gemma":[0.96261567,0.032366987,0.00035458192,0.00027418777,0.0039910404,0.000019874426,0.000045189685,0.000018827122,0.00031365393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990232,0.00005986526,0.000259519,0.0003802738,0.00012451681,0.00015261293],"domain_scores_gemma":[0.99932784,0.00004646503,0.00008078612,0.00033280422,0.00017171136,0.00004041683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007910951,0.00021908108,0.00020049365,0.000071589115,0.00014231929,0.000033287823,0.00016902559,0.00019670099,0.000008566409],"category_scores_gemma":[0.000010024162,0.00015330903,0.000051569732,0.00021732622,0.00012988532,0.000006244567,0.000068560694,0.00012564409,6.7135824e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024385481,0.000080284386,0.00023862292,0.00000964087,0.000088017994,7.486916e-7,0.0027713203,0.00003610811,0.9907299,0.000080888145,0.0027651442,0.0029554714],"study_design_scores_gemma":[0.0015761079,0.00023393599,0.0020787446,0.00000835901,0.000012777623,6.4126635e-7,0.0005069541,0.000020120115,0.8582882,0.00059823546,0.13651079,0.0001651255],"about_ca_topic_score_codex":0.00005002359,"about_ca_topic_score_gemma":0.000016161504,"teacher_disagreement_score":0.13374564,"about_ca_system_score_codex":0.000006747526,"about_ca_system_score_gemma":0.00007877974,"threshold_uncertainty_score":0.6251761},"labels":[],"label_agreement":null},{"id":"W7115816413","doi":"","title":"Environmental DNA and the context of CRISPR adaptation","year":2024,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Context (archaeology); DNA; Genome; Gene; Bacteria; Metagenomics; Cas9","score_opus":0.004735276626468005,"score_gpt":0.20645931056148675,"score_spread":0.20172403393501875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7115816413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6696832,0.016444562,0.0038394067,0.00013138808,0.0012101096,0.00087674,0.00017565925,0.000034314027,0.3076046],"genre_scores_gemma":[0.8018021,0.00055820995,0.000052121588,0.000018558525,0.0000547181,9.200897e-7,0.0002185708,0.00001921754,0.19727561],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99949354,0.000026574739,0.000099475496,0.00021391413,0.00007729415,0.00008917239],"domain_scores_gemma":[0.9997701,0.000009706354,0.000053862786,0.00012648411,0.000011129132,0.000028706836],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000038329315,0.00013856795,0.00013331157,0.000036366364,0.00003449971,0.000013247808,0.000111517336,0.00014354588,0.0011342565],"category_scores_gemma":[0.0000043218515,0.00012189359,0.00008590368,0.00004657315,0.00006839943,0.000002455214,0.00005314862,0.0000930461,0.0000059080453],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015559663,0.00005083287,0.00014106993,0.00058249244,0.00066915544,0.000024628196,0.0073118256,0.00027424644,0.24170673,0.001766099,0.0015926305,0.7443243],"study_design_scores_gemma":[0.002671129,0.00021876176,0.0009597423,0.00015473865,0.000557173,0.000010965407,0.05890421,0.00087764254,0.23477726,0.0000771686,0.7002888,0.00050242076],"about_ca_topic_score_codex":0.000035439927,"about_ca_topic_score_gemma":0.00028765286,"teacher_disagreement_score":0.7438219,"about_ca_system_score_codex":0.0000110925475,"about_ca_system_score_gemma":0.000020219328,"threshold_uncertainty_score":0.99977887},"labels":[],"label_agreement":null},{"id":"W7116671186","doi":"10.1093/nar/gkaf1358","title":"Casδ, an evolutionary transitional CRISPR system enables efficient genome editing across animals and plants","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China","keywords":"CRISPR; Genome editing; Indel; Genome; Nuclease; Homing endonuclease; INDEL Mutation; Effector; Palindrome; DNA","score_opus":0.019819092727498433,"score_gpt":0.36896502776085227,"score_spread":0.34914593503335384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116671186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99002194,0.002710084,0.0053691356,0.00012031485,0.00011425943,0.00021602528,0.00015670789,0.00002818251,0.0012633306],"genre_scores_gemma":[0.9984658,0.000092142705,0.0007058696,0.000024169818,0.00034657036,0.00003194024,0.000091124,0.000018579094,0.00022385511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847466,0.00010557262,0.00018596019,0.0004248326,0.0003058338,0.00050311454],"domain_scores_gemma":[0.99940336,0.000031407548,0.000015790389,0.00026035882,0.00016284839,0.00012621585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071611244,0.00012696827,0.00013050577,0.00009875587,0.00040722868,0.00006598838,0.00019538114,0.00015421763,0.000013827169],"category_scores_gemma":[0.000045290057,0.00012942124,0.00004031634,0.00014990984,0.00015322438,0.000004097202,0.00018229114,0.00019374173,0.0000074466398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012818357,0.0000664242,0.0015142206,0.00026366502,0.00005418114,0.00002681029,0.00042799185,0.0027481385,0.99194664,0.00061478966,0.00064168277,0.0015673031],"study_design_scores_gemma":[0.0047107507,0.0016571295,0.38972834,0.0007226978,0.000058304788,0.0006890065,0.035980638,0.070688486,0.4423109,0.00033320894,0.051578302,0.0015422308],"about_ca_topic_score_codex":0.00003304283,"about_ca_topic_score_gemma":0.000011285673,"teacher_disagreement_score":0.5496357,"about_ca_system_score_codex":0.00004999076,"about_ca_system_score_gemma":0.00008359577,"threshold_uncertainty_score":0.5277645},"labels":[],"label_agreement":null},{"id":"W7116745901","doi":"10.1002/sstr.202500674","title":"Cas12Fold Accurately Predicts Cas12 Nuclease Structures to Enable Structure‐based Genome‐editing Engineering","year":2025,"lang":"en","type":"article","venue":"Small Structures","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; National Science and Technology Major Project; Chinese Universities Scientific Fund; China Agricultural University","keywords":"Inference; Key (lock); Protein engineering; Rational design; Mutagenesis; Sequence (biology); Robustness (evolution)","score_opus":0.010450604609110735,"score_gpt":0.27591997459405937,"score_spread":0.26546936998494863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116745901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97235644,0.0012586785,0.023742877,0.00014611668,0.0010750736,0.0004860662,0.00020115866,0.000116396564,0.0006171718],"genre_scores_gemma":[0.9875405,0.000011422253,0.010414491,0.0007495075,0.00077672326,0.000024071465,0.00019345216,0.00006630125,0.00022354141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980603,0.000030258167,0.00036711304,0.0006895206,0.00019487127,0.00065792375],"domain_scores_gemma":[0.9988969,0.000027214228,0.00007123792,0.0006329911,0.00011752403,0.00025411314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000091420115,0.00045459214,0.00030301654,0.0002302871,0.00016612452,0.00011975646,0.00048457875,0.00028504088,0.00009414069],"category_scores_gemma":[0.00030005164,0.00044721976,0.000133142,0.0003112324,0.000049432518,0.0000068075706,0.00023286624,0.00025705426,0.0000029049581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068550486,0.000008117386,0.0005377804,0.00015517624,0.00010749398,0.000017803626,0.00009600251,0.22112158,0.77458125,0.000517666,0.0011461955,0.001642386],"study_design_scores_gemma":[0.0009655293,0.00016833558,0.021403512,0.000050077386,0.00008387735,0.000033508953,0.00014500362,0.0021221582,0.9195202,0.0005743758,0.054243572,0.00068983797],"about_ca_topic_score_codex":0.000081564474,"about_ca_topic_score_gemma":0.00015890917,"teacher_disagreement_score":0.21899942,"about_ca_system_score_codex":0.000050472598,"about_ca_system_score_gemma":0.00013101393,"threshold_uncertainty_score":0.99979794},"labels":[],"label_agreement":null},{"id":"W7116863797","doi":"10.64898/2025.12.19.695556","title":"Pooled CRISPRi screening reveals fungal-specific vulnerabilities across environments and genetic backgrounds","year":2025,"lang":"en","type":"article","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Guelph","funders":"Fonds de Recherche du Québec - Santé; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada","keywords":"Gene; Genomics; Psychological repression; Phenotype; Genetic screen; Gene regulatory network; Exploit; Genetic Fitness; Strain (injury)","score_opus":0.008102710338526957,"score_gpt":0.25016618614133135,"score_spread":0.24206347580280438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116863797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93599355,0.010552932,0.052665606,0.00009535325,0.0003325512,0.00025170256,0.000037574675,0.000049940438,0.00002080293],"genre_scores_gemma":[0.9921673,0.0010043072,0.0060414886,0.00026041185,0.00021211062,0.0000604738,4.5533707e-7,0.000056478777,0.00019697877],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819815,0.00006926111,0.00034703902,0.0006974111,0.00016140596,0.00052673207],"domain_scores_gemma":[0.9989548,0.000027279451,0.0000709543,0.00072863005,0.000060898183,0.00015746507],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027370718,0.00032616593,0.00026037917,0.00007628295,0.00020054923,0.00012592072,0.00024000289,0.00022885208,0.000013730309],"category_scores_gemma":[0.00007015828,0.00036617927,0.00007998771,0.00020651131,0.0001522216,0.000011850976,0.0002369253,0.00017291414,0.000009650151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028770437,0.00003489358,0.024356263,0.000052545984,0.00009390411,0.000012059537,0.000009232249,0.00014428646,0.9745137,0.00009602638,0.0006188027,0.00003948138],"study_design_scores_gemma":[0.0006631788,0.0000735012,0.36084944,0.00006430196,0.000035401783,1.240248e-7,0.000022416943,0.00010299013,0.59665275,0.0000014329617,0.041128736,0.0004057159],"about_ca_topic_score_codex":0.000009573729,"about_ca_topic_score_gemma":0.0000018023741,"teacher_disagreement_score":0.377861,"about_ca_system_score_codex":0.0000481759,"about_ca_system_score_gemma":0.00005091864,"threshold_uncertainty_score":0.999879},"labels":[],"label_agreement":null},{"id":"W7116888737","doi":"10.1093/nar/gkaf1402","title":"HyperdCas12a-based multiplexed genetic regulation in <i>Candida albicans</i>","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"CRISPR; Genetic screen; Candida albicans; Gene; Human genetics; Functional genomics; Phenotype; Genome editing; Forward genetics; Mutant","score_opus":0.01721103123689934,"score_gpt":0.3590179739754146,"score_spread":0.34180694273851525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116888737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98038894,0.0008597719,0.01180852,0.0005015279,0.00011634374,0.00038076943,0.000007482642,0.000021978265,0.005914678],"genre_scores_gemma":[0.995432,0.000057472254,0.0025133144,0.00013781567,0.00009026344,0.00006192511,0.000037993377,0.000023393224,0.0016458271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998556,0.00012124937,0.00021862757,0.00040086263,0.00026851293,0.00043475657],"domain_scores_gemma":[0.9992537,0.000045840115,0.000015823374,0.00048562462,0.00012437791,0.000074671356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043877575,0.00012700843,0.00012993753,0.0002706791,0.000091447495,0.000035522782,0.0002705935,0.00017706196,0.000062217696],"category_scores_gemma":[0.00020071673,0.00013366764,0.000057270703,0.00052116974,0.00011287553,0.000002521509,0.00012898709,0.00022753085,0.000019447974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010239899,0.000060377763,0.019914715,0.000039673923,0.000013670799,0.000007627743,0.000036857913,0.003674556,0.9633794,0.000048907317,0.0023912122,0.01033065],"study_design_scores_gemma":[0.0022267078,0.00023797301,0.32854146,0.00008578844,0.000008357364,0.000005453393,0.00016470421,0.014846332,0.5582219,0.00024241772,0.095116705,0.0003021918],"about_ca_topic_score_codex":0.00008874885,"about_ca_topic_score_gemma":0.00013602908,"teacher_disagreement_score":0.40515745,"about_ca_system_score_codex":0.000053938013,"about_ca_system_score_gemma":0.00016471227,"threshold_uncertainty_score":0.5450808},"labels":[],"label_agreement":null},{"id":"W7116888880","doi":"10.64229/e5whn229","title":"CRISPR-Cas9-Mediated Crop Genome Editing: From Basic Research to Breeding Applications","year":2025,"lang":"","type":"article","venue":"Plant Scientific Application","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"CRISPR; Food security; Genome editing; Genomics; Basic research; Translational research; Paradigm shift; Agriculture; Emerging technologies","score_opus":0.022588090685783314,"score_gpt":0.3494072830755334,"score_spread":0.3268191923897501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7116888880","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14871606,0.0044724396,0.8317691,0.002205526,0.0016379947,0.003407367,0.00336934,0.0000934436,0.0043286905],"genre_scores_gemma":[0.98523736,0.00020441861,0.0016596288,0.00016429131,0.0012690062,0.0013323874,0.007231909,0.000043416556,0.0028575973],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958078,0.000100509336,0.00069132284,0.0018708425,0.0006398118,0.0008896941],"domain_scores_gemma":[0.99720454,0.00016391948,0.00013544131,0.0014995321,0.0006282256,0.0003683224],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016734744,0.00035183446,0.00029559358,0.0005910962,0.0011357225,0.0005337715,0.001031848,0.00038098445,0.00006553775],"category_scores_gemma":[0.00024165116,0.00041388106,0.000117081705,0.0021660314,0.00032045002,0.000012729134,0.0006239973,0.00042633156,0.00064308336],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043744283,0.0001465169,0.00039546366,0.00009417374,0.000069748356,9.706683e-7,0.00026686856,0.0008622643,0.9663284,0.00057173753,0.018682385,0.012537762],"study_design_scores_gemma":[0.00031960302,0.000053686545,0.00145418,0.000070345035,0.00005666813,0.0000027437484,0.000478083,0.0063814186,0.20124155,0.00032524046,0.78925204,0.00036442807],"about_ca_topic_score_codex":0.00014043598,"about_ca_topic_score_gemma":0.00015712602,"teacher_disagreement_score":0.83652127,"about_ca_system_score_codex":0.00016216411,"about_ca_system_score_gemma":0.00031705675,"threshold_uncertainty_score":0.9998313},"labels":[],"label_agreement":null},{"id":"W7117248700","doi":"10.1080/10409238.2025.2577956","title":"CRISPR-Cas9 editing of agricultural crops and medicinal plants: toward a cornucopia of natural products","year":2025,"lang":"en","type":"article","venue":"Critical Reviews in Biochemistry and Molecular Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Nutraceutical; Agriculture; Human health; Adaptation (eye); Genome editing; Medicinal plants; Natural (archaeology); Metabolic engineering; Abiotic component; Plant metabolism","score_opus":0.008669551722037807,"score_gpt":0.35409814307072046,"score_spread":0.34542859134868265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117248700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8523057,0.14315978,0.0031738472,0.00057284394,0.00018949374,0.00020482134,0.00002175599,0.0000044298185,0.00036732055],"genre_scores_gemma":[0.9933659,0.0045443266,0.0017477314,0.00014740662,0.00007842099,0.000016849839,0.0000629806,0.000005868223,0.00003050708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881524,0.00006591326,0.00044452655,0.00039302956,0.000052547577,0.00022872601],"domain_scores_gemma":[0.99954176,0.000043363445,0.00006343244,0.00020281962,0.00009222315,0.000056425553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024800954,0.00018401473,0.0004062964,0.00004055815,0.000021917162,0.0000052825217,0.00012642595,0.00019731399,0.0000027379301],"category_scores_gemma":[0.0017502973,0.0001487723,0.000051904175,0.00011180403,0.00042129122,0.0000024689848,0.00015938049,0.00015392726,1.4974171e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002759153,0.00003059963,0.0008025784,0.0012452744,0.000022133097,0.0000030912963,0.00002253068,5.3180173e-7,0.9929769,0.00086621137,0.00020335751,0.0037991945],"study_design_scores_gemma":[0.00034169998,0.00012624059,0.0018601553,0.00047548674,0.00003525525,0.000049879596,0.00011428547,0.000008602304,0.9942715,0.00018572154,0.0023892967,0.00014187733],"about_ca_topic_score_codex":0.0000074627287,"about_ca_topic_score_gemma":0.0000017131039,"teacher_disagreement_score":0.1410602,"about_ca_system_score_codex":0.0000062284776,"about_ca_system_score_gemma":0.000036973972,"threshold_uncertainty_score":0.60667586},"labels":[],"label_agreement":null},{"id":"W7117252386","doi":"10.4103/genc.genc_36_25","title":"Enhancing Accuracy in the Diagnosis and Treatment of Genetic Disorders","year":2025,"lang":"en","type":"article","venue":"Genetic Clinics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Genome engineering; Genome editing; CRISPR; Cas9; Genome; Plasmid; Human genome; Zinc finger nuclease; Guide RNA; Gene","score_opus":0.01201849840735452,"score_gpt":0.3430496147153066,"score_spread":0.33103111630795207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117252386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9793634,0.0140015865,0.005845494,0.0002037641,0.000116075054,0.0002870011,0.0000056057484,0.000003542445,0.00017355714],"genre_scores_gemma":[0.9666528,0.03060923,0.0024051596,0.00011109908,0.000055454202,0.0000860243,0.0000070640995,0.000009184332,0.00006400185],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9991744,0.000045008346,0.00031634496,0.00023912585,0.0000625913,0.00016252595],"domain_scores_gemma":[0.9994089,0.0001557588,0.000047558864,0.00034600595,0.00001722532,0.000024535942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001044526,0.00012380217,0.00014689448,0.00004922421,0.000032028056,0.00001146989,0.00013446143,0.00008659992,0.0000056390277],"category_scores_gemma":[0.00012141294,0.00009844971,0.000068016765,0.000106623746,0.000053653614,7.90167e-7,0.000049254337,0.00003888179,9.809997e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048642374,0.00035111513,0.44820765,0.000087545246,0.000102992155,0.0000036111098,0.00077890296,0.0041684723,0.020802705,0.00004444859,0.0002108331,0.5251931],"study_design_scores_gemma":[0.0019599309,0.0011155532,0.84642035,0.0000659528,0.000127231,0.0000069998882,0.00068416423,0.00085406704,0.064936176,0.0006968461,0.082805745,0.00032699408],"about_ca_topic_score_codex":0.000045127985,"about_ca_topic_score_gemma":0.0004825242,"teacher_disagreement_score":0.5248661,"about_ca_system_score_codex":0.000006810508,"about_ca_system_score_gemma":0.00004500482,"threshold_uncertainty_score":0.40146628},"labels":[],"label_agreement":null},{"id":"W7117413438","doi":"10.1016/j.psj.2025.106344","title":"A rapid, visual, ultrasensitive and highly specific method for detecting adeno-associated virus 2020 based on the LAMP-CRISPR/Cas12a system","year":2025,"lang":"en","type":"article","venue":"Poultry Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"Natural Science Foundation of Hubei Province","keywords":"Porcine parvovirus; Parvovirus; Virus; Parvoviridae; Genome; Phylogenetic tree; Loop-mediated isothermal amplification; Subfamily","score_opus":0.009447393437335224,"score_gpt":0.3128106350092665,"score_spread":0.30336324157193123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117413438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59930694,0.0008650193,0.3965278,0.0009820163,0.00050811615,0.0006461502,0.00004959533,0.00005321665,0.001061171],"genre_scores_gemma":[0.99625057,0.000045154884,0.0030415247,0.00039454523,0.00008387647,0.000034027948,0.000008439558,0.000011216755,0.000130665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998774,0.00007874301,0.00016907383,0.00049096526,0.00016874347,0.00031850993],"domain_scores_gemma":[0.9991705,0.00031269641,0.00006049315,0.0002506645,0.00013622355,0.00006946529],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010580507,0.00015502726,0.00014021556,0.00007162256,0.000383853,0.00009116567,0.0002120143,0.00008416584,0.0000018535212],"category_scores_gemma":[0.0006956653,0.0001207544,0.00006315117,0.00042955962,0.00012409504,0.000004685857,0.000058881084,0.000102757294,0.0000017675264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052906697,0.000021905073,0.00027743,0.000027764434,0.000016018334,0.0000017952601,0.000050375776,0.00059302896,0.9938246,0.00017973573,0.00039455845,0.0045598852],"study_design_scores_gemma":[0.0004404092,0.00018981125,0.004024908,0.00008178483,0.000020931173,0.0000065178556,0.0011338774,0.036168303,0.9544484,0.000010276332,0.0032996286,0.00017513822],"about_ca_topic_score_codex":0.000020671338,"about_ca_topic_score_gemma":0.0000098552455,"teacher_disagreement_score":0.39694363,"about_ca_system_score_codex":0.00004335744,"about_ca_system_score_gemma":0.00009863271,"threshold_uncertainty_score":0.49242216},"labels":[],"label_agreement":null},{"id":"W7117579014","doi":"10.30683/1927-7229.2025.14.15","title":"Precision Reprogramming of Lung Cancer Biomarkers via CRISPR/Cas9: A Paradigm Shift in Personalized Immunotherapy","year":2025,"lang":"","type":"article","venue":"Journal of Analytical Oncology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Immunotherapy; Biomarker; Reprogramming; CRISPR; Epigenetics; Immune system; Immune checkpoint; Precision medicine; Cancer immunotherapy","score_opus":0.009511809304085822,"score_gpt":0.3849306752463554,"score_spread":0.3754188659422696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117579014","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.56856954,0.12438138,0.29435736,0.008829762,0.0020197555,0.00063468056,0.000017037839,0.0000059177646,0.001184605],"genre_scores_gemma":[0.9858888,0.0119094895,0.0015091231,0.00023102251,0.00024637644,0.000009385917,0.0000039060815,0.000027126083,0.00017479877],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965152,0.00031225677,0.0018680143,0.00044831564,0.00031148153,0.0005446972],"domain_scores_gemma":[0.9982245,0.00026367753,0.00070677605,0.00038954554,0.00022223074,0.00019326617],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0014812286,0.00034434133,0.0011857095,0.00055681664,0.00005340247,0.000028857523,0.0004656625,0.00066977745,0.00016202274],"category_scores_gemma":[0.00032203383,0.00031853523,0.00071085186,0.0006742048,0.00035674227,0.000012822595,0.00013638097,0.0005712776,6.2454376e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.026092011,0.004397024,0.11184989,0.0014082514,0.012561706,0.0007516056,0.0023793175,0.012038645,0.298291,0.0023158079,0.005108732,0.52280605],"study_design_scores_gemma":[0.045794737,0.017122125,0.10137458,0.005010119,0.0046595526,0.0008551702,0.0017725507,0.12547083,0.10124534,0.0049136714,0.5890697,0.002711582],"about_ca_topic_score_codex":0.00010646105,"about_ca_topic_score_gemma":0.00011213194,"teacher_disagreement_score":0.583961,"about_ca_system_score_codex":0.00035221849,"about_ca_system_score_gemma":0.0011638893,"threshold_uncertainty_score":0.9999267},"labels":[],"label_agreement":null},{"id":"W7125771455","doi":"10.5220/0014431700004933","title":"Advancements in CRISPR Technology for Studying Antibiotic Resistance Mechanisms in Bacteria","year":2025,"lang":"","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"CRISPR; Bacteria; Antibiotic resistance; Antibiotics","score_opus":0.006923867355795084,"score_gpt":0.3171705464653447,"score_spread":0.3102466791095496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7125771455","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38284332,0.013730889,0.5959426,0.0012652803,0.001320662,0.0020579975,0.000033667387,0.000031305502,0.002774224],"genre_scores_gemma":[0.9708754,0.0012726244,0.024849098,0.00016110008,0.000030474526,0.0000857466,0.000027234228,0.000030329475,0.002667998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977407,0.000034474877,0.00065426313,0.00081738236,0.000084726555,0.00066847727],"domain_scores_gemma":[0.9992445,0.000025145246,0.000073813804,0.00053608837,0.00007578915,0.0000446409],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003262217,0.00033311956,0.00041702928,0.0005251695,0.00006485662,0.000033281332,0.00035925186,0.00042570222,0.00001800956],"category_scores_gemma":[0.00013407957,0.00038959293,0.00008402374,0.00071235065,0.000055577733,0.0000059142417,0.0002654263,0.00018040657,0.000002323968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029086493,0.00030802275,0.0062042032,0.0005773045,0.00008267136,0.000010053057,0.000053379903,0.00065607176,0.97559476,0.0057370737,0.00023046981,0.0102551],"study_design_scores_gemma":[0.0038385612,0.00028761683,0.0042085797,0.0006316368,0.000037812504,0.0000014017874,0.0011040706,0.0008320415,0.9678107,0.003214664,0.017489167,0.0005437758],"about_ca_topic_score_codex":0.0000119657025,"about_ca_topic_score_gemma":0.0011450519,"teacher_disagreement_score":0.58803207,"about_ca_system_score_codex":0.00009420207,"about_ca_system_score_gemma":0.00012730462,"threshold_uncertainty_score":0.9998556},"labels":[],"label_agreement":null},{"id":"W7126480473","doi":"","title":"Heritable Human Genome Editing: The Public Engagement Imperative","year":2020,"lang":"en","type":"article","venue":"Bristol Research (University of Bristol)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Warrant; Genetic discrimination; Bioethics; Commission; Public engagement; Public policy; Human genome; Public health; Remedial education","score_opus":0.07197275678118441,"score_gpt":0.34273141710023247,"score_spread":0.27075866031904805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7126480473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9612824,0.0020961512,0.018567165,0.009504312,0.000076338765,0.00054585177,0.000060270286,0.00003501044,0.007832556],"genre_scores_gemma":[0.99793607,0.00014641738,0.0004575204,0.00007494718,0.00021253349,0.0000014150105,0.00006454967,0.00001603837,0.0010904861],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985952,0.00021199173,0.0001124322,0.00034085603,0.00036833002,0.00037122922],"domain_scores_gemma":[0.99909997,0.000025155938,0.000051039537,0.00033521547,0.00029490644,0.0001937246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066935143,0.000108439504,0.00014766773,0.000060780123,0.00062852824,0.000039173516,0.0006507941,0.00007920969,0.00014437917],"category_scores_gemma":[0.00018108283,0.000116846866,0.000098772536,0.00028901105,0.00033287655,0.00001074764,0.00056844327,0.0003128316,0.00002977334],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060774193,0.000089754285,0.0005441782,0.00008617615,0.00013804414,0.00004445188,0.0020148095,0.00018901829,0.945623,0.0007078106,0.048233755,0.0022682508],"study_design_scores_gemma":[0.0008211116,0.00072564103,0.0049677524,0.000012882132,0.000021531954,0.000010702622,0.016871328,0.00060639373,0.018403774,0.000049726397,0.95723456,0.0002745908],"about_ca_topic_score_codex":0.00015982351,"about_ca_topic_score_gemma":0.00016686582,"teacher_disagreement_score":0.9272192,"about_ca_system_score_codex":0.000044865687,"about_ca_system_score_gemma":0.000120851786,"threshold_uncertainty_score":0.48341945},"labels":[],"label_agreement":null},{"id":"W7131861923","doi":"10.5376/cge.2024.12.0028","title":"Gene Editing Approaches in Ovarian Cancer Current Research and Future Applications","year":2024,"lang":"","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genome editing; Ovarian cancer; Current (fluid); Gene; Genetic enhancement","score_opus":0.06142971170102045,"score_gpt":0.3939063531362535,"score_spread":0.33247664143523303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7131861923","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15718326,0.8299006,0.0076499837,0.0016873077,0.001959937,0.0009642288,0.00037322665,0.000016746748,0.00026470728],"genre_scores_gemma":[0.5265743,0.4656449,0.00086886866,0.00002594406,0.006069189,0.00052536174,0.00005957152,0.00008284091,0.00014902743],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963456,0.00010690898,0.00065498985,0.0014690375,0.00038620437,0.0010372899],"domain_scores_gemma":[0.99864787,0.00005015089,0.000070247974,0.00059812615,0.00020497818,0.00042864148],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062486046,0.00054872624,0.000412689,0.0003310079,0.00031348973,0.00038593897,0.00032729673,0.0005245996,0.00004282994],"category_scores_gemma":[0.000012240336,0.0005995693,0.000089439076,0.00072180654,0.00046684386,0.000008558252,0.00053656474,0.00082881475,0.0000030538768],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029470924,0.00013538456,0.014147702,0.0019322524,0.00021494577,0.000011595422,0.0012024244,0.0036701772,0.03070169,0.0007753295,0.0006547571,0.94652426],"study_design_scores_gemma":[0.0007245367,0.00025430683,0.011995293,0.0005040625,0.0001825634,0.000025557156,0.00087488117,0.016270764,0.07749131,0.0010678591,0.8895922,0.0010166886],"about_ca_topic_score_codex":0.000114819035,"about_ca_topic_score_gemma":0.00061944197,"teacher_disagreement_score":0.9455076,"about_ca_system_score_codex":0.00011458102,"about_ca_system_score_gemma":0.0005002684,"threshold_uncertainty_score":0.9996456},"labels":[],"label_agreement":null},{"id":"W7131883188","doi":"10.5376/cge.2025.13.0005","title":"The Role of CRISPR/Cas9 in Targeting HER2-Positive Breast Cancer: Current Research and Future Perspectives","year":2025,"lang":"","type":"article","venue":"Cancer Genetics and Epigenetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Current (fluid); Breast cancer; MEDLINE; Disease","score_opus":0.007851747785891748,"score_gpt":0.3599968696934852,"score_spread":0.35214512190759345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7131883188","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36418805,0.6323681,0.00028280003,0.0014823405,0.0006724075,0.00046394888,0.0002737167,0.0000035128783,0.0002650969],"genre_scores_gemma":[0.5273615,0.47169626,0.000102921746,0.000014896161,0.0006153917,0.000066100474,0.000008561739,0.000029093748,0.000105249244],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968742,0.00021290909,0.00069550995,0.00095445424,0.0003425828,0.00092032447],"domain_scores_gemma":[0.99814737,0.00011950042,0.00015757867,0.00053776446,0.0008211466,0.00021667038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00066279,0.00047149652,0.0004642754,0.00020580368,0.00051554374,0.0001514397,0.0004181248,0.00037512454,0.000013621952],"category_scores_gemma":[0.00004160511,0.00043225082,0.000102421334,0.0005936942,0.00096958847,0.0000057602497,0.00067065016,0.0006466666,3.4598264e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034876808,0.00029587795,0.12732086,0.00061149837,0.0004222801,0.0000033255096,0.004222919,0.00206911,0.069365494,0.0021655804,0.0006412212,0.7925331],"study_design_scores_gemma":[0.0017838343,0.00062146527,0.21784219,0.0009939086,0.00026563578,0.000012275795,0.031546857,0.0054186718,0.3051328,0.0025700838,0.43265876,0.0011535265],"about_ca_topic_score_codex":0.0003944719,"about_ca_topic_score_gemma":0.0009249487,"teacher_disagreement_score":0.7913796,"about_ca_system_score_codex":0.000120980716,"about_ca_system_score_gemma":0.00059196417,"threshold_uncertainty_score":0.9998129},"labels":[],"label_agreement":null},{"id":"W7132497936","doi":"","title":"Disentangled wasserstein autoencoder for T-cell receptor engineering","year":2023,"lang":"en","type":"article","venue":"NPARC","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autoencoder; Process (computing); Domain (mathematical analysis); Sequence (biology); Function (biology); Protein engineering; Baseline (sea)","score_opus":0.007328098056756645,"score_gpt":0.2677549627467119,"score_spread":0.26042686468995524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132497936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88736916,0.00020586973,0.10766854,0.00042567562,0.00078611926,0.00042270686,0.000054566794,0.00018434397,0.0028830054],"genre_scores_gemma":[0.98236245,0.000070535716,0.012736178,0.000046595484,0.0003556439,0.0000965694,0.0002132833,0.00004566089,0.0040731123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993817,0.0000046410864,0.00010325885,0.00020432366,0.00006463144,0.00024139759],"domain_scores_gemma":[0.99969846,0.000013341047,0.000014815186,0.00018574187,0.000023213217,0.000064436994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008204302,0.00010309066,0.00008212172,0.00004049602,0.000033443266,0.0000132870855,0.00010267093,0.0000715133,0.000036096026],"category_scores_gemma":[0.000042780357,0.00010745579,0.00008033123,0.00009877164,0.000007921351,0.0000013677897,0.000047394442,0.00003649539,0.000036772664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012753449,0.0000110593255,0.00010149284,0.000039264745,0.00001425336,6.7485723e-7,0.00002754936,0.0031353305,0.9755988,0.00005495637,0.02042016,0.0005837177],"study_design_scores_gemma":[0.00051902776,0.00010257942,0.00021561373,0.000008859038,0.000011086586,0.0000012919255,0.000055491157,0.025070028,0.85538596,0.000050724204,0.11838488,0.00019447906],"about_ca_topic_score_codex":6.02503e-7,"about_ca_topic_score_gemma":0.0000013348522,"teacher_disagreement_score":0.120212846,"about_ca_system_score_codex":0.000008051607,"about_ca_system_score_gemma":0.00001557368,"threshold_uncertainty_score":0.43819198},"labels":[],"label_agreement":null},{"id":"W7132962139","doi":"","title":"Exploring Cell-free Synthetic Biology Tools for De-centralized Diagnostics and Protein Manufacturing","year":2020,"lang":"","type":"dissertation","venue":"TSpace","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University of Toronto; Arizona State University","keywords":"Synthetic biology; Field (mathematics); Colistin; Work (physics); Food supply; Coronavirus disease 2019 (COVID-19); Food security; Tracking (education)","score_opus":0.042645183423001366,"score_gpt":0.3350982462717603,"score_spread":0.29245306284875894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132962139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9546178,0.008359107,0.033474468,0.00036679066,0.0005711537,0.0019983782,0.0000871635,0.000038073344,0.00048706957],"genre_scores_gemma":[0.97737384,0.010535297,0.008412582,0.00006058425,0.00051874545,0.0010793707,0.0008750199,0.00015275067,0.0009918079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99765867,0.00007241485,0.00043826777,0.0009303227,0.00011408181,0.00078623963],"domain_scores_gemma":[0.99863434,0.00018823177,0.00020285323,0.00057773397,0.00007711545,0.00031975406],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017479867,0.00061789394,0.00054959045,0.00007667281,0.0001836387,0.00014099792,0.00040579008,0.0005392022,0.000025477131],"category_scores_gemma":[0.0010469313,0.00071264966,0.00022544336,0.0000619334,0.00006541955,0.00001013536,0.00020147726,0.00030920494,0.0000042477627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042547323,0.00007125044,0.00003668728,0.0022430243,0.00017485897,0.000010544174,0.0026497128,0.0003055839,0.97815776,0.00015968837,0.00015842536,0.0156069705],"study_design_scores_gemma":[0.0015858483,0.000726104,0.00023855479,0.000256827,0.00023954509,0.000007918153,0.0028153406,0.0004558906,0.9544681,0.0000936529,0.038350828,0.00076141173],"about_ca_topic_score_codex":0.000034155342,"about_ca_topic_score_gemma":0.000021836317,"teacher_disagreement_score":0.038192403,"about_ca_system_score_codex":0.00004319876,"about_ca_system_score_gemma":0.00014793189,"threshold_uncertainty_score":0.99953246},"labels":[],"label_agreement":null},{"id":"W7132971283","doi":"","title":"Structural and Mechanistic Characterization of Type II-C Anti-CRISPR Proteins","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cas9; Cleave; CRISPR; DNA; Genome; Mutagenesis; Structural biology; Gene; Chemical biology; Synthetic biology","score_opus":0.010237990168982646,"score_gpt":0.32536200093202994,"score_spread":0.3151240107630473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132971283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955496,0.0007440163,0.0018968873,0.000039527822,0.0010291205,0.00057240616,0.000044504897,0.000021874122,0.00010202989],"genre_scores_gemma":[0.98845756,0.0016460932,0.00024770925,0.000009449583,0.00022317737,0.00001932517,0.0030333225,0.00008469415,0.006278694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986214,0.000033147524,0.0003574942,0.00051305164,0.00018297319,0.00029194538],"domain_scores_gemma":[0.9990785,0.000008083842,0.00024747828,0.00033887263,0.00023034119,0.00009673655],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000982006,0.00036731747,0.00038875686,0.00011114431,0.00014433824,0.000028183877,0.00015060381,0.00044784707,0.00006183449],"category_scores_gemma":[0.000112617156,0.00040264713,0.00008230341,0.00022701565,0.00004552698,0.0000034857787,0.00011998681,0.00016669028,0.00000610758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000901999,0.00001566877,0.00009489702,0.0006810134,0.00010450889,0.0000026035482,0.0016696843,0.0000931329,0.99525595,0.00006153576,0.000014790528,0.0019160097],"study_design_scores_gemma":[0.00039166654,0.00067775836,0.016601413,0.00021638804,0.00015994192,0.000009829411,0.0011540888,0.0024846245,0.97713745,0.000023021741,0.00065504963,0.0004888002],"about_ca_topic_score_codex":0.000058956208,"about_ca_topic_score_gemma":0.000028580478,"teacher_disagreement_score":0.018118538,"about_ca_system_score_codex":0.000011132978,"about_ca_system_score_gemma":0.000114264956,"threshold_uncertainty_score":0.9998425},"labels":[],"label_agreement":null},{"id":"W7133061292","doi":"","title":"Discovery and Characterization of Small-molecule CRISPR/Cas13 Inhibitors Using a High Throughput Platform","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Palindrome; DNA; Gene; Genome editing; RNA; In vitro; Cell; Fluorescence","score_opus":0.01642483763929631,"score_gpt":0.3272125192909326,"score_spread":0.3107876816516363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133061292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98212314,0.0011202294,0.014798536,0.000039244016,0.0012337298,0.0004908773,0.00007435515,0.000023601442,0.000096314194],"genre_scores_gemma":[0.98959976,0.002784536,0.0004963639,0.00002362669,0.00046387463,0.000022444045,0.0031281319,0.00015329762,0.003327967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997903,0.000034084558,0.0006058833,0.0007682797,0.00023973134,0.00044902836],"domain_scores_gemma":[0.99879193,0.000022827502,0.00043826213,0.00046872348,0.00016658405,0.00011165372],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015646325,0.0005590836,0.0005559508,0.00018031184,0.00013589852,0.00010202599,0.00018293994,0.000685801,0.000010954853],"category_scores_gemma":[0.00007334516,0.00063130737,0.00018893971,0.00030187445,0.00008977086,0.000017349534,0.00018216558,0.0002441988,0.0000037998077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000152219,0.00004988334,0.00021262515,0.0008241517,0.00018693635,0.000007784468,0.0023907418,0.00033850642,0.9947919,0.000035843885,0.000019629488,0.0009897295],"study_design_scores_gemma":[0.000595067,0.00031218113,0.005112689,0.0004821726,0.00024882748,0.000013584036,0.0033652415,0.0017917884,0.9871984,0.000012620903,0.00021670677,0.00065069017],"about_ca_topic_score_codex":0.00047311746,"about_ca_topic_score_gemma":0.00014248291,"teacher_disagreement_score":0.014302173,"about_ca_system_score_codex":0.00003627791,"about_ca_system_score_gemma":0.00019166055,"threshold_uncertainty_score":0.9996138},"labels":[],"label_agreement":null},{"id":"W7133075664","doi":"","title":"Microhomology-Mediated End Joining and mRNA Reframing as Therapeutic CRISPR/Cas9 Editing Strategies for c.1278insTATC Mutation of Tay-Sachs Disease","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"HEXA; Frameshift mutation; Gene duplication; Mutation; Disease; Indel; Messenger RNA; Cleavage (geology)","score_opus":0.013456062209541375,"score_gpt":0.36187111917877113,"score_spread":0.34841505696922975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133075664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96697545,0.0143329,0.01591663,0.00018411706,0.0011756616,0.00091631047,0.00015977725,0.000052307958,0.00028684823],"genre_scores_gemma":[0.98992515,0.0020888182,0.0012224542,0.00007683085,0.00047411045,0.00014588714,0.004404595,0.00016715379,0.0014950022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974023,0.00009555276,0.0007143268,0.00089498574,0.00025231868,0.0006404832],"domain_scores_gemma":[0.9982413,0.00025005892,0.000549093,0.00039384322,0.00033848034,0.00022719978],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040139817,0.000613706,0.0005902674,0.00023714548,0.00025467013,0.00011393912,0.00021499614,0.00060307473,0.00002759378],"category_scores_gemma":[0.0005089135,0.000708352,0.0002018195,0.00022642162,0.00016072375,0.000015714144,0.00007917109,0.00032646587,0.0000058864107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055730407,0.000077831646,0.00020862218,0.0022661877,0.0004714823,0.000036908772,0.011211623,0.0022603963,0.9702533,0.00012320004,0.00014336972,0.012389799],"study_design_scores_gemma":[0.0040666,0.0028066894,0.008514939,0.0015011593,0.0017728462,0.00007339431,0.23414218,0.013519976,0.72574365,0.0013435688,0.0041965167,0.0023184647],"about_ca_topic_score_codex":0.00022330154,"about_ca_topic_score_gemma":0.00017670632,"teacher_disagreement_score":0.24450961,"about_ca_system_score_codex":0.000031466207,"about_ca_system_score_gemma":0.0005511363,"threshold_uncertainty_score":0.99953675},"labels":[],"label_agreement":null},{"id":"W7135039367","doi":"10.5376/ijmms.2024.14.0022","title":"Prospects of Gene Editing Technologies in Sickle Cell Anemia","year":2024,"lang":"","type":"article","venue":"International Journal of Molecular Medical Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Genome editing; Sickle cell anemia; Gene; Cell; Disease; Mutation","score_opus":0.004175122651352425,"score_gpt":0.3049669018498713,"score_spread":0.30079177919851885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7135039367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8934751,0.030881206,0.067346945,0.003410707,0.0035693417,0.00011561133,0.000010117602,0.000011606803,0.0011793649],"genre_scores_gemma":[0.9953829,0.0011909,0.002926715,0.000055762972,0.00040039237,0.0000017351712,0.0000021492544,0.00001331591,0.000026098192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99670315,0.000027215729,0.00074517634,0.0003386397,0.0018659858,0.0003198271],"domain_scores_gemma":[0.99894494,0.00003677853,0.00020751751,0.00017575896,0.00047471016,0.0001602941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014676431,0.000164574,0.00021910934,0.00046159193,0.000024217703,0.00008596101,0.0015119833,0.0002139812,0.00004254186],"category_scores_gemma":[0.001529177,0.00014665273,0.00015761386,0.0005494581,0.000674537,0.00002391996,0.00035017572,0.00047520187,0.0000025556913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021578253,0.00009676033,0.0004354061,0.00007528847,0.000031740798,0.0011759382,0.000113087735,0.00153067,0.96629405,0.00022713201,0.00009498026,0.029903363],"study_design_scores_gemma":[0.0004224798,0.00024494287,0.00018670583,0.0006428992,0.000017241658,0.00051599095,0.00026642322,0.0037069793,0.9911906,0.0002393325,0.002430419,0.00013596046],"about_ca_topic_score_codex":0.000007110663,"about_ca_topic_score_gemma":0.0000031830089,"teacher_disagreement_score":0.101907834,"about_ca_system_score_codex":0.000106500105,"about_ca_system_score_gemma":0.0012156607,"threshold_uncertainty_score":0.5980325},"labels":[],"label_agreement":null},{"id":"W7139232359","doi":"","title":"Assessing a Novel Dual-Endonuclease System in Restoring CFTR Expression in Cystic Fibrosis Models","year":2025,"lang":"","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cystic fibrosis transmembrane conductance regulator; Cystic fibrosis; Chloride channel; Genetic enhancement; Mutation; Lung; Electroporation; Regulator","score_opus":0.013987885758920697,"score_gpt":0.28127537071042075,"score_spread":0.26728748495150007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7139232359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91916084,0.009248788,0.056219373,0.000023180046,0.00060479244,0.0005638133,0.00005055464,0.000025078136,0.01410356],"genre_scores_gemma":[0.9887313,0.001038233,0.00814063,0.000002392685,0.000055508885,0.000003394557,0.00023765024,0.000035795605,0.001755081],"study_design_codex":"bench_or_experimental","study_design_gemma":"qualitative","domain_scores_codex":[0.99795866,0.00010615627,0.00036801305,0.0008166148,0.0002868469,0.000463698],"domain_scores_gemma":[0.9987758,0.000049345716,0.0003153121,0.00058210536,0.00013764524,0.00013983717],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028469058,0.00043850284,0.0006519835,0.00021316714,0.00015130057,0.000043328764,0.00037601564,0.0007084941,0.00012870893],"category_scores_gemma":[0.00005500556,0.0006463864,0.00022844638,0.00017495695,0.00004011785,0.00008637561,0.00026457652,0.0002974814,0.0000010681952],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00094626565,0.00029342363,0.00052188226,0.0039994693,0.000104113205,0.000087069595,0.0101700425,0.110287905,0.8620089,0.00011427229,0.000042578602,0.011424027],"study_design_scores_gemma":[0.010640783,0.0006437863,0.17384204,0.028085193,0.00068675267,0.00002305122,0.37793064,0.29219958,0.11185046,0.0000101524665,0.0010670957,0.0030204486],"about_ca_topic_score_codex":0.046394505,"about_ca_topic_score_gemma":0.04839338,"teacher_disagreement_score":0.7501585,"about_ca_system_score_codex":0.00068829797,"about_ca_system_score_gemma":0.00033277788,"threshold_uncertainty_score":0.99959874},"labels":[],"label_agreement":null},{"id":"W7143697583","doi":"10.71465/ajbt2489","title":"Biotechnology for the Development of Smart Agricultural Practices","year":2023,"lang":"","type":"article","venue":"American Journal of Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Agriculture; Agricultural biotechnology; Food security; Environmental biotechnology; Genetic engineering; Agricultural productivity","score_opus":0.012646165250688854,"score_gpt":0.3126477118628928,"score_spread":0.30000154661220396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7143697583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9254073,0.0057803798,0.05084796,0.01652886,0.00096090196,0.00038264468,0.0000241054,0.000035214547,0.000032640135],"genre_scores_gemma":[0.9823091,0.0060335873,0.011206099,0.00005283107,0.00022462325,0.000018784265,0.000009439505,0.000033573207,0.00011193801],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769515,0.000059431495,0.0011156115,0.00034797128,0.00021259683,0.0005692378],"domain_scores_gemma":[0.9963119,0.00024506444,0.0025918745,0.00050829846,0.00026166558,0.00008118018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008809794,0.00031266452,0.0006320607,0.000418751,0.00017790534,0.000018432054,0.0010276982,0.0005475758,0.0000067772953],"category_scores_gemma":[0.00095934246,0.00021663566,0.00031462157,0.0011226337,0.001093343,0.00000788405,0.0003474269,0.000497464,0.000007070811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002113071,0.00006574671,0.000120043405,0.000050668084,0.00074374187,0.0000041579096,0.00024148947,0.00028938812,0.656234,0.00016175353,0.0007220019,0.34115565],"study_design_scores_gemma":[0.00053087034,0.0027844284,0.0011339283,0.000049836774,0.00016968968,0.0002521265,0.00773859,0.00014755588,0.82622975,0.00002739676,0.1606977,0.00023812482],"about_ca_topic_score_codex":0.000009141202,"about_ca_topic_score_gemma":0.000050117193,"teacher_disagreement_score":0.34091753,"about_ca_system_score_codex":0.00003384005,"about_ca_system_score_gemma":0.00036958436,"threshold_uncertainty_score":0.88341457},"labels":[],"label_agreement":null},{"id":"W7160623090","doi":"10.1109/becithcon69222.2025.11504111","title":"Designing a Dry-Lab Pipeline for Multiplex CRISPR µPAD Assays against Dengue and Chikungunya","year":2025,"lang":"","type":"article","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lockheed Martin (Canada)","funders":"","keywords":"Chikungunya; Dengue fever; Multiplex; Pipeline (software); CRISPR","score_opus":0.008422880579626327,"score_gpt":0.30626252990412955,"score_spread":0.29783964932450324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7160623090","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03237912,0.014474243,0.9450797,0.0004101266,0.0006874274,0.0010408112,0.000064827844,0.000043926095,0.0058198334],"genre_scores_gemma":[0.9446805,0.0023071605,0.04175718,0.00083065947,0.00046125575,0.000117514646,0.00016751322,0.000065825516,0.009612371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99742365,0.00006974283,0.0006397645,0.000983582,0.00013537238,0.0007478857],"domain_scores_gemma":[0.9987337,0.00013552661,0.00009735675,0.0005686279,0.00023868438,0.00022611335],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004951345,0.0005553715,0.00047479424,0.00016126283,0.00029487268,0.00013633523,0.0002908168,0.00052138837,0.000022830865],"category_scores_gemma":[0.00053645624,0.0005818355,0.00023691899,0.00021227157,0.00012229451,0.000006807656,0.0003372387,0.00023093476,0.0000030250728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001676733,0.00012455715,0.002483759,0.00056994235,0.0003315549,0.000005589001,0.00018776368,0.0022764201,0.92088675,0.00041681828,0.0051481803,0.06740099],"study_design_scores_gemma":[0.0034362765,0.00018076067,0.00057489873,0.0001786539,0.00022625538,0.0000055934543,0.0007237852,0.08608801,0.8059619,0.00009906893,0.10176133,0.000763431],"about_ca_topic_score_codex":0.000028104887,"about_ca_topic_score_gemma":0.00013483035,"teacher_disagreement_score":0.9123014,"about_ca_system_score_codex":0.000033527947,"about_ca_system_score_gemma":0.00018646083,"threshold_uncertainty_score":0.9996633},"labels":[],"label_agreement":null},{"id":"W7161970090","doi":"10.82308/27324","title":"CRISPR/Cas9 based gene editing in wheat and potato to enhance multiple disease resistance","year":2024,"lang":"en","type":"dissertation","venue":"","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Plant disease resistance; Plant tissue; Environmental factor; Fungi imperfecti","score_opus":0.0037024413370624894,"score_gpt":0.3008536015879738,"score_spread":0.2971511602509113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7161970090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9763163,0.013644257,0.0067996616,0.000304276,0.0007425677,0.0004420738,0.000084683576,0.000037090962,0.0016290942],"genre_scores_gemma":[0.9801299,0.00020681172,0.003163667,0.00019839322,0.00036195846,0.00011820908,0.0010396432,0.000065088054,0.014716352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876046,0.000015555715,0.00023273962,0.0006118375,0.00012432906,0.0002550985],"domain_scores_gemma":[0.99945307,0.000015427597,0.000027960696,0.00027824924,0.000049671067,0.00017563373],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000089705376,0.00025252797,0.00017806623,0.00010800913,0.000033979366,0.00004643493,0.000107331514,0.0001613852,0.000015852725],"category_scores_gemma":[0.00014618319,0.0002669472,0.00006411635,0.00011193293,0.000009717176,0.0000018609089,0.000037324346,0.00013393673,0.00000981226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035286948,0.000038097496,0.0007086567,0.0010793679,0.00003177274,0.00005783755,0.00023129361,0.0011876201,0.98615456,0.000014846916,0.0077962917,0.0023468072],"study_design_scores_gemma":[0.00024897864,0.000047857106,0.0064148894,0.0004387389,0.00004120135,8.889865e-7,0.0003073381,0.001096406,0.9704046,0.000028471326,0.020455798,0.0005148285],"about_ca_topic_score_codex":0.00003578505,"about_ca_topic_score_gemma":0.0043382575,"teacher_disagreement_score":0.015749935,"about_ca_system_score_codex":0.000018171238,"about_ca_system_score_gemma":0.000083561616,"threshold_uncertainty_score":0.99997824},"labels":[],"label_agreement":null},{"id":"W7165391491","doi":"10.70177/agriculturae.v2i6.2964","title":"CRISPR/CAS9-MEDIATED GENETIC ENGINEERING FOR DEVELOPING SALINITY-TOLERANT RICE VARIETIES FOR INDONESIAN COASTAL AGRICULTURE","year":2025,"lang":"","type":"article","venue":"Techno Agriculturae Studium of Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; University of Alberta","funders":"","keywords":"Agriculture; Salinity; Soil salinity; Biomass (ecology); Greenhouse; Crop; Sustainable agriculture; Crop yield","score_opus":0.01868435436924454,"score_gpt":0.36177383763295085,"score_spread":0.3430894832637063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7165391491","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.33368176,0.027593618,0.62046295,0.0042079147,0.0017075947,0.010300779,0.0011048608,0.00026172627,0.00067882077],"genre_scores_gemma":[0.97924644,0.002390585,0.014773766,0.000042436317,0.00060868886,0.0014014317,0.00046899775,0.00006860413,0.0009990246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952413,0.00010051475,0.0011323519,0.0012113581,0.0007566353,0.0015578709],"domain_scores_gemma":[0.995304,0.00064979325,0.00022124522,0.0006659681,0.0029667711,0.00019224772],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013447951,0.0007545058,0.0009284508,0.00053318456,0.0006819927,0.00015091345,0.0010835007,0.0010225076,0.0000030312792],"category_scores_gemma":[0.0014878493,0.00060971203,0.0004783981,0.0020812377,0.00032903705,0.000016812879,0.00087938417,0.00079010625,0.0000031528534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004050068,0.00034331577,0.00055714045,0.005405792,0.0011381602,0.000007407282,0.00040436533,0.001743257,0.9703403,0.0017256067,0.015706178,0.002223456],"study_design_scores_gemma":[0.003715168,0.0013894752,0.017258743,0.0007835937,0.0003249139,0.000028047489,0.0053439434,0.0016084019,0.8946564,0.00026779968,0.07331961,0.0013038667],"about_ca_topic_score_codex":0.00010749565,"about_ca_topic_score_gemma":0.00015972246,"teacher_disagreement_score":0.64556473,"about_ca_system_score_codex":0.00015623451,"about_ca_system_score_gemma":0.00052418903,"threshold_uncertainty_score":0.9996354},"labels":[],"label_agreement":null},{"id":"W800577","doi":"10.1042/bst20130164","title":"Programmable DNA cleavage <i>in vitro</i> by Cas9","year":2013,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Social Fund; Centre for Addiction and Mental Health","keywords":"Trans-activating crRNA; CRISPR; Cas9; Endonuclease; Genome editing; DNA; Biology; Computational biology; RNA; Cell biology; Genetics; Gene","score_opus":0.012423999199939827,"score_gpt":0.30866187101219766,"score_spread":0.29623787181225786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W800577","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006764346,0.9852577,0.013406723,0.000028323257,0.00013778236,0.0006717365,0.00021735691,0.000041804313,0.00017092034],"genre_scores_gemma":[0.00025407693,0.99429226,0.0021756405,0.00005182582,0.00016982648,0.00049068447,0.0010544235,0.00008474675,0.0014265351],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983015,0.000030887888,0.00043777245,0.0005976638,0.00014187279,0.00049031817],"domain_scores_gemma":[0.9993214,0.000018710572,0.00007376653,0.00039265363,0.000024882867,0.00016855933],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009315115,0.00042943214,0.0006321247,0.000022342621,0.0000701203,0.000042293468,0.0002680307,0.0008542324,0.000042295236],"category_scores_gemma":[0.000007314347,0.00040975402,0.0009924188,0.00023460087,0.000090493006,0.0000033714614,0.000023527351,0.0004377127,0.000031702657],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000064764567,0.00025311238,1.6711027e-7,0.0037293935,0.00031166812,0.0000012260447,0.00002820441,0.0000049126274,0.34672666,6.105287e-7,0.07025448,0.5786831],"study_design_scores_gemma":[0.00017671206,0.000026061056,5.749915e-8,0.00024009148,0.00016849535,0.000015529045,0.000019211022,0.0000150039405,0.14030863,0.0000010176096,0.8586396,0.0003895663],"about_ca_topic_score_codex":0.000038227667,"about_ca_topic_score_gemma":0.0000022377894,"teacher_disagreement_score":0.78838515,"about_ca_system_score_codex":0.00006697274,"about_ca_system_score_gemma":0.0000958982,"threshold_uncertainty_score":0.99983543},"labels":[],"label_agreement":null},{"id":"W817942150","doi":"10.1139/y05-042","title":"Decondensation of<i>Xenopus</i>sperm chromatin using<i>Saccharomyces cerevisiae</i>whole-cell extractsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chromatin; Biology; Xenopus; Micrococcal nuclease; Mutant; Saccharomyces cerevisiae; Sperm; Molecular biology; Cell biology; Genetics; Gene; Nucleosome","score_opus":0.0054548219396787076,"score_gpt":0.2407613423919789,"score_spread":0.23530652045230022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W817942150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99673307,0.0013668248,0.000015175865,0.00013929894,0.00034360323,0.00013276847,0.000036120593,8.791506e-7,0.0012322748],"genre_scores_gemma":[0.9985206,0.00015817716,0.00031032256,0.00016249782,0.0006622775,0.000002125465,0.000011958581,0.000012814887,0.00015920882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989062,0.00012559812,0.0005294421,0.00015988182,0.00006954973,0.00020932041],"domain_scores_gemma":[0.9991637,0.00003666309,0.00047133688,0.000093332375,0.00014906569,0.00008589941],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028544417,0.00013184843,0.00032001582,0.0001537983,0.00004952845,0.0000065203176,0.00016020794,0.0001835499,0.010756937],"category_scores_gemma":[0.00001572003,0.00011599625,0.000092041875,0.0001446089,0.00017169448,0.00001541688,0.00001868965,0.00019445822,9.902286e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009809559,0.00007603487,0.0010352219,0.00015400976,0.000045984503,0.0000023835523,0.00048966653,0.0010332084,0.99150795,0.000006183034,0.0054912404,0.00006003288],"study_design_scores_gemma":[0.0011426462,0.00032062308,0.0022294442,0.0000204061,0.00009642062,0.000019083338,0.00014756853,0.000117542535,0.9894072,0.00008917933,0.006307867,0.00010203059],"about_ca_topic_score_codex":0.0011098377,"about_ca_topic_score_gemma":0.0018177785,"teacher_disagreement_score":0.010755947,"about_ca_system_score_codex":0.000022863165,"about_ca_system_score_gemma":0.0003482746,"threshold_uncertainty_score":0.99014735},"labels":[],"label_agreement":null},{"id":"W853742876","doi":"","title":"Topical small molecule translational bypass therapy rescues Pax6 aniridia mutant phenotype","year":2013,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"PAX6; Aniridia; Phenotype; Mutant; Small molecule; Medicine; Genetics; Biology; Gene","score_opus":0.028109377732553245,"score_gpt":0.33430373108912204,"score_spread":0.3061943533565688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W853742876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99706346,0.00040027645,0.00028154097,0.0005249233,0.00017577008,0.00026125932,0.0000048859497,0.00001849057,0.0012694229],"genre_scores_gemma":[0.9969212,0.000021055319,0.0023758214,0.00030755813,0.00015927729,0.000051818963,0.00001929831,0.000015780008,0.00012822967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851197,0.00007545938,0.00021281184,0.00055577804,0.0002131385,0.00043084944],"domain_scores_gemma":[0.999278,0.000028687566,0.00005026283,0.00023435545,0.00018006795,0.00022861309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002240325,0.00019730344,0.00015293961,0.00006306263,0.0001800953,0.00005040455,0.00038359128,0.00013453726,0.00015963045],"category_scores_gemma":[0.00015589061,0.0001737382,0.000060507435,0.0002825689,0.0013563249,0.00001536064,0.00010066882,0.00013725249,0.00004098637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014472402,0.000046679204,0.007302521,0.0000030937256,0.00001591637,0.000009557427,0.0001575871,0.00010092392,0.9915775,0.00010353958,0.00005508256,0.0006131136],"study_design_scores_gemma":[0.00026825472,0.00050653866,0.10170156,0.0000061081832,0.0000037202435,0.00005564957,0.00005222833,0.00052817364,0.8951813,0.0012093689,0.0002766028,0.00021047794],"about_ca_topic_score_codex":0.00008201215,"about_ca_topic_score_gemma":0.000004280408,"teacher_disagreement_score":0.09639619,"about_ca_system_score_codex":0.000015138488,"about_ca_system_score_gemma":0.00021162136,"threshold_uncertainty_score":0.7084838},"labels":[],"label_agreement":null},{"id":"W865322094","doi":"","title":"Novel Hyperactive Transposons Enable Stable Transfection Of Isolated, Terminally Differentiated Cells Immediately After Isolation From A Biopsy","year":2011,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Transfection; Isolation (microbiology); Cell biology; Transposable element; Chemistry; Medicine; Biology; Cell culture; Genetics; Bioinformatics; Biochemistry; Gene","score_opus":0.022701758392916122,"score_gpt":0.2945196877441445,"score_spread":0.2718179293512284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W865322094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992501,0.00010167811,0.0064749457,0.000009851609,0.00027497803,0.00021887787,0.00008804963,0.000013191588,0.0003174181],"genre_scores_gemma":[0.99596256,0.000011116534,0.0038070586,0.000021536918,0.000047927784,0.000036742586,0.000040015606,0.000018591285,0.000054425494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985742,0.000056926605,0.00028118986,0.0005526124,0.00017169629,0.00036336295],"domain_scores_gemma":[0.9992986,0.000024382185,0.00010403609,0.00020034709,0.00021200419,0.00016063498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017830502,0.00021721744,0.00021492461,0.000121131794,0.000106205,0.000014696056,0.00023660918,0.00017731087,0.000117410564],"category_scores_gemma":[0.000053152064,0.00020799792,0.000075325814,0.00038680714,0.00093285926,0.000035863686,0.000051721807,0.00013958843,0.000006604628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002218704,0.00018328562,0.008756425,0.000010615112,0.000040410854,0.000012153762,0.001192492,0.000061126986,0.98945564,0.0000029345547,0.0000014448266,0.00006158861],"study_design_scores_gemma":[0.0003572677,0.00069224084,0.14016141,0.000023180643,0.000037455073,0.000041618285,0.00015924605,0.0007144661,0.85747784,0.00013458601,0.000006008298,0.00019467888],"about_ca_topic_score_codex":0.00059386867,"about_ca_topic_score_gemma":0.00001863944,"teacher_disagreement_score":0.13197781,"about_ca_system_score_codex":0.000023921095,"about_ca_system_score_gemma":0.00015239317,"threshold_uncertainty_score":0.84819084},"labels":[],"label_agreement":null},{"id":"W903110834","doi":"","title":"Hope and hype in sight: Sensationalism in choroideremia gene therapy","year":2012,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Alexandra Hospital; University of Alberta","funders":"","keywords":"Choroideremia; Sensationalism; Sight; Optometry; Ophthalmology; Medicine; Astronomy; Physics; Sociology; Media studies; Retinal","score_opus":0.02787708215855406,"score_gpt":0.3536665701449138,"score_spread":0.32578948798635976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W903110834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99780846,0.0014569697,0.000011863251,0.00013479928,0.00011665984,0.00013598205,0.000002015857,0.0000041544386,0.00032912],"genre_scores_gemma":[0.998613,0.000056690755,0.0009776821,0.00015855266,0.0000924079,0.000019166619,0.000008376766,0.000008915451,0.00006520308],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892074,0.00006809935,0.0001659876,0.00033518908,0.00012787395,0.0003820936],"domain_scores_gemma":[0.9996204,0.00002676097,0.000038105878,0.00012459244,0.000040632032,0.00014953502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005255446,0.00013261991,0.0001224126,0.00012306427,0.0000594426,0.00001561837,0.00014534948,0.00010179126,0.000014436745],"category_scores_gemma":[0.00017532124,0.00012460497,0.000016260019,0.00035319082,0.0008856588,0.000020044936,0.000109771674,0.00010872202,0.0000039300085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008107595,0.000030637275,0.1943541,0.000001771932,0.0000024386832,0.000007267056,0.0003793029,0.0000859489,0.8047888,0.00003161606,0.0000047183225,0.00030525477],"study_design_scores_gemma":[0.00019417041,0.000072778326,0.46613362,0.0000046298373,6.4567774e-7,0.00006866266,0.000052104664,0.000081681115,0.5330237,0.00018235913,0.00008894219,0.00009669676],"about_ca_topic_score_codex":0.00020737799,"about_ca_topic_score_gemma":0.0000356649,"teacher_disagreement_score":0.27177954,"about_ca_system_score_codex":0.000031928128,"about_ca_system_score_gemma":0.00011272562,"threshold_uncertainty_score":0.5081243},"labels":[],"label_agreement":null},{"id":"W928073071","doi":"","title":"病毒载体诱导转录后基因沉默系统的建立及烟草（Nicotiana benthamiana）rbcs基因功能的研究","year":2003,"lang":"zh","type":"article","venue":"分子植物育种","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Nicotiana benthamiana; Nicotiana; Biology; Virology; Genetics; Solanaceae; Virus","score_opus":0.006394604695645631,"score_gpt":0.2718789370558344,"score_spread":0.26548433236018876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W928073071","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2587439,0.09573759,0.0391763,0.0008440127,0.006070461,0.001142895,0.00021692256,0.00014576077,0.59792215],"genre_scores_gemma":[0.9873578,0.001567887,0.0011837408,0.00031957577,0.000654157,0.000017589238,0.000079247475,0.00009607487,0.008723916],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975761,0.00013973925,0.00044027503,0.0007731064,0.0002618137,0.00080895773],"domain_scores_gemma":[0.9984976,0.000020972344,0.00009967803,0.00095216034,0.00009425936,0.00033532293],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034976343,0.0004736926,0.0003425837,0.000089679386,0.00015634483,0.00008164818,0.00034449113,0.00046504685,0.000501033],"category_scores_gemma":[0.00018528578,0.00052762014,0.0003010874,0.00022464208,0.00011341745,0.000005523651,0.00012098122,0.00027842814,0.00031625348],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010092056,0.0011052578,0.019409355,0.0007280735,0.0014384695,0.00017459838,0.00084418413,0.005269858,0.8120727,0.02925838,0.087950125,0.04164806],"study_design_scores_gemma":[0.0017439085,0.00049848534,0.0054908074,0.00009111508,0.00020065434,0.0001308425,0.000449212,0.00016680358,0.29789862,0.0007329296,0.6912571,0.0013394791],"about_ca_topic_score_codex":0.000035146004,"about_ca_topic_score_gemma":0.000084409585,"teacher_disagreement_score":0.7286139,"about_ca_system_score_codex":0.000042222367,"about_ca_system_score_gemma":0.00017479084,"threshold_uncertainty_score":0.99971753},"labels":[],"label_agreement":null},{"id":"W93487","doi":"10.1007/978-94-007-2941-4_37","title":"Horizontal Gene Transfer and the Tree of Life","year":2012,"lang":"en","type":"book-chapter","venue":"Cellular origin and life in extreme habitats","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Tree of life (biology); Horizontal gene transfer; Tree (set theory); Gene transfer; Transfer (computing); Biology; Gene; Genetics; Mathematics; Computer science; Phylogenetic tree; Combinatorics; Parallel computing","score_opus":0.027167053347505812,"score_gpt":0.23971455102614783,"score_spread":0.212547497678642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W93487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46315753,0.46076694,0.008640254,0.0003732165,0.00092492305,0.0012235696,0.00012374368,0.000028521146,0.06476131],"genre_scores_gemma":[0.97583556,0.010805045,0.00030029003,0.00009713737,0.00063138333,0.000015978987,0.00009431789,0.000071099195,0.012149199],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99888676,0.00002777377,0.00036888197,0.0003377152,0.00014328389,0.00023557602],"domain_scores_gemma":[0.9993948,0.00003415099,0.00005294833,0.00031189815,0.000031298725,0.00017494732],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002589971,0.00031460883,0.0004364101,0.000072520656,0.000037123278,0.00001537665,0.00013744243,0.00033229464,0.00004298989],"category_scores_gemma":[0.00003025684,0.00024828652,0.00013250469,0.000020362282,0.00028882167,0.0000033855692,0.000072795934,0.000207262,0.0000035965568],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017748484,0.00020722166,0.0069060028,0.001419404,0.0012053326,0.00005682522,0.0019087461,0.000092707574,0.85599405,0.07696171,0.0032902644,0.050182916],"study_design_scores_gemma":[0.010913258,0.00062225043,0.0023926343,0.0003617984,0.00057487754,0.00006675315,0.00019876548,0.00031299551,0.09398068,0.0020210524,0.8864634,0.0020915568],"about_ca_topic_score_codex":0.000026669837,"about_ca_topic_score_gemma":0.00009168651,"teacher_disagreement_score":0.8831731,"about_ca_system_score_codex":0.0000068137692,"about_ca_system_score_gemma":0.000060833507,"threshold_uncertainty_score":0.99999696},"labels":[],"label_agreement":null},{"id":"W989483129","doi":"10.71781/26245","title":"Characterization of the AP endonuclease enzyme APN-1 from C. elegans","year":2007,"lang":"en","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Endonuclease; Enzyme; Biology; Computational biology; Genetics; Molecular biology; Biochemistry","score_opus":0.002829420474846456,"score_gpt":0.1905122173375434,"score_spread":0.18768279686269693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W989483129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98782456,0.0035464945,0.0009644484,0.000024322866,0.0007899816,0.0001885603,0.00014012876,0.000016071923,0.0065054293],"genre_scores_gemma":[0.981703,0.0002657853,0.00012325661,0.00004439153,0.0002459993,0.000005755052,0.001950121,0.000025124993,0.015636563],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900514,0.000031021897,0.00022321996,0.00030557165,0.00025796567,0.00017709419],"domain_scores_gemma":[0.99922174,0.000010380205,0.00020632618,0.0003537377,0.00011921738,0.000088587454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057221303,0.00020869775,0.00016699592,0.00007259613,0.00077646645,0.000011865449,0.00028133026,0.00032863877,0.000016362817],"category_scores_gemma":[0.000025023217,0.00020664038,0.00020035454,0.000105688894,0.00006216341,0.00000713343,0.000080178215,0.00015603422,0.0000040277137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024273818,0.0000425607,0.0012695979,0.000038065355,0.00012349128,0.000031776053,0.0015136852,0.00030178108,0.99484676,0.00014911493,0.00008871719,0.0013517191],"study_design_scores_gemma":[0.00033296144,0.000033012937,0.06624864,0.00006715883,0.00011775263,0.000031031912,0.0012854657,0.00009087335,0.90328103,0.0000103379025,0.028290832,0.0002109177],"about_ca_topic_score_codex":0.0028841703,"about_ca_topic_score_gemma":0.0021360272,"teacher_disagreement_score":0.091565736,"about_ca_system_score_codex":0.00026697217,"about_ca_system_score_gemma":0.00037745415,"threshold_uncertainty_score":0.84265506},"labels":[],"label_agreement":null},{"id":"W990711347","doi":"10.1016/b978-012677530-3/50236-1","title":"Mechanisms of Gene Exchange Between Bacteria","year":2002,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Transduction (biophysics); Horizontal gene transfer; DNA; Biology; Bacteria; Plasmid; Naked DNA; Gene; Transformation (genetics); Genome; Gene transfer; Genetics; Exogenous DNA; Bacterial conjugation; Cell biology; Biochemistry","score_opus":0.013589910706515086,"score_gpt":0.25116215548856663,"score_spread":0.23757224478205155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W990711347","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00060973514,0.002667563,0.0015597241,0.000010648152,0.00029578587,0.00032995275,0.00020414511,0.000020123007,0.99430233],"genre_scores_gemma":[0.01751803,0.00041726578,0.0022720506,0.00005531716,0.0006137401,0.000017247177,0.0002497136,0.00012403849,0.9787326],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99883705,0.000011046958,0.0003538536,0.0003968415,0.00016724033,0.00023398043],"domain_scores_gemma":[0.9990863,0.0000068829563,0.00015534672,0.00058308634,0.00006551259,0.0001028789],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010132377,0.00035070544,0.0004204566,0.00007654652,0.000029136512,0.00001015483,0.00024926828,0.00047847445,0.00030960797],"category_scores_gemma":[0.0000066855046,0.00036749468,0.00023697806,0.000006573144,0.000054154003,7.434314e-7,0.00010439702,0.00015121762,0.000034729826],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009913858,0.0000061282067,0.0000045134093,0.00018962495,0.0002618503,0.0000074509235,0.00004896326,0.0000021756666,0.31333777,0.00038910712,0.00025899275,0.6854835],"study_design_scores_gemma":[0.00020775528,0.00016765941,0.000046304613,0.00008672779,0.000112610665,0.000009639041,0.0000014419835,0.0000012659946,0.24310796,0.0008349077,0.75505316,0.00037057942],"about_ca_topic_score_codex":2.5845168e-7,"about_ca_topic_score_gemma":0.0000027039112,"teacher_disagreement_score":0.7547942,"about_ca_system_score_codex":0.000012440338,"about_ca_system_score_gemma":0.000024728293,"threshold_uncertainty_score":0.9998777},"labels":[],"label_agreement":null}]}